{"pmid": "4194633", "title": "Alterations of the cortical oxygen pressure in generalized seizures.", "content": "Alterations of the cortical oxygen pressure in generalized seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194633"} {"pmid": "4194632", "title": "Further results of stimulation experiments in kittens.", "content": "Further results of stimulation experiments in kittens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194632"} {"pmid": "4194634", "title": "Psychological findings in cases with 4-5 c-sec rhythm.", "content": "Psychological findings in cases with 4-5 c-sec rhythm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194634"} {"pmid": "4194635", "title": "Side to side comparison of acoustic evoked potentials in patients with unilateral intracerebral processes, especially with aphasia.", "content": "Side to side comparison of acoustic evoked potentials in patients with unilateral intracerebral processes, especially with aphasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194635"} {"pmid": "4194637", "title": "Fourier analysis of on- and off-effects of evoked potentials.", "content": "Fourier analysis of on- and off-effects of evoked potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194637"} {"pmid": "4194636", "title": "Human cortical evoked potentials in dichoptic stimulation.", "content": "Human cortical evoked potentials in dichoptic stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194636"} {"pmid": "4194638", "title": "Artefacts in the \"silent\" EEG.", "content": "Artefacts in the \"silent\" EEG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194638"} {"pmid": "4194639", "title": "The development of sleep spindles during the first 2 years of life.", "content": "The development of sleep spindles during the first 2 years of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194639"} {"pmid": "4194641", "title": "The value of the EEG recorded with open eyes for differential diagnosis of intracerebral processes: behaviour of physiological and pathological activity.", "content": "The value of the EEG recorded with open eyes for differential diagnosis of intracerebral processes: behaviour of physiological and pathological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194641"} {"pmid": "4194640", "title": "The reaction of alpha activity during exercise.", "content": "The reaction of alpha activity during exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194640"} {"pmid": "4194642", "title": "Experiments on cholinergic mechanisms for the control of tonic and phasic components of REM sleep.", "content": "Experiments on cholinergic mechanisms for the control of tonic and phasic components of REM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194642"} {"pmid": "4194643", "title": "EEG changes in Jakob-Creutzfeldt's disease under the influence of diazepam.", "content": "EEG changes in Jakob-Creutzfeldt's disease under the influence of diazepam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194643"} {"pmid": "4194645", "title": "Demonstration of technical novelties in the field of clinical electroencephalography.", "content": "Demonstration of technical novelties in the field of clinical electroencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194645"} {"pmid": "4194644", "title": "EEG changes with facial injuries.", "content": "EEG changes with facial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194644"} {"pmid": "4194646", "title": "A study of axon reflexes in some neurological disorders.", "content": "A study of axon reflexes in some neurological disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194646"} {"pmid": "4194647", "title": "Auditory evoked responses. The basis for a promising objective audiometric test.", "content": "Auditory evoked responses. The basis for a promising objective audiometric test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194647"} {"pmid": "4194648", "title": "The effect of diazepam (Valium) and nitrazepam (Mogadon) on picrotoxin induced seizures in rabbits.", "content": "The effect of diazepam (Valium) and nitrazepam (Mogadon) on picrotoxin induced seizures in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194648"} {"pmid": "4194649", "title": "The size of the ventricular system. A comparative study between echoencephalography and pneumoencephalography.", "content": "The size of the ventricular system. A comparative study between echoencephalography and pneumoencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194649"} {"pmid": "4194650", "title": "The epileptogenic effect of water-soluble contrast media. A search for less toxic substances.", "content": "The epileptogenic effect of water-soluble contrast media. A search for less toxic substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194650"} {"pmid": "4194651", "title": "Mitochondrial RNA from cultured animal cells. II. A comparison of the high molecular weight RNA from mouse and hamster cells.", "content": "Mitochondrial RNA from cultured animal cells. II. A comparison of the high molecular weight RNA from mouse and hamster cells. Discrete RNA fractions sedimenting slightly slower than 18s ribosomal RNA have been found in mitochondrial preparations from both hamster (BHK-21) and mouse (L-929) cells. This RNA could be separated into two components, present in approximately equimolar amounts, by prolonged zonal centrifugation or acrylamide gel electrophoresis. The hamster components had sedimentation constants averaging 16.8 and 13.4, and molecular weights (estimated by gel electrophoresis) averaging 0.74 and 0.42 x 10(6) daltons. Mixed labeling experiments showed that the mouse components sedimented and electrophoresed 3-6% more slowly than the corresponding hamster components. The RNA from both cell lines resembled mitochondrial ribosomal RNA from yeast and Neurospora in being GC poor, and in addition the larger and smaller components resembled each other in base composition. These results, taken with those of other recent studies, are compatible with the idea that our high molecular weight mitochondrial RNA is ribosomal; such RNA would then constitute a uniquely small size-class of ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194651"} {"pmid": "4194652", "title": "Osmium staining of endoplasmic reticulum and mitochondria in the rat adrenal cortex.", "content": "Osmium staining of endoplasmic reticulum and mitochondria in the rat adrenal cortex. The zona fasciculata of the rat adrenal cortex synthesizes and secretes glucocorticoids. As observed after aldehyde fixation, the cells in this zone contain an extensive endoplasmic reticulum (ER), a small Golgi apparatus, a moderate number of lipid droplets, and abundant mitochondria with tubulovesicular cristae. Numerous areas within the endoplasmic reticulum and mitochondrial cristae appear clear. In addition, a small percentage of mitochondria encompasses large, clear areas. After immersion of finely minced adrenal cortex in unbuffered 2% OsO(4) (40-48 hr at 40 degrees C), deposits of osmium are seen within the Golgi apparatus, the entirety of the ER, and occasionally within mitochondria. In some mitochondria, the deposits are within cristae; in others, within vacuoles; in still others, in both cristae and vacuoles. These localizations correspond best to the clear areas found in aldehyde-fixed tissue. Osmium is not deposited in lipid droplets, in bar-containing inclusions, in mitochondrial matrix inclusions, or in the peripheral, outer mitochondrial spaces. Addition of zinc-iodide to OsO(4) increases the amount of Golgi apparatus and mitochondrial staining. Adrenocorticotropin (ACTH) does not affect the localization of deposits; hypophysectomy decreases mitochondrial staining. This study (a) emphasizes the necessity for electron microscopic confirmation of osmium localization when this technique is used as a Golgi apparatus stain; and (b) suggests that the ER-staining pattern may be consistent in cells actively synthesizing steroids or steroid-like compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194652"} {"pmid": "4194654", "title": "Cytologic specificity of response to Moloney murine sarcoma virus as evident in a transplantable epithelioid neoplasm of the rat.", "content": "Cytologic specificity of response to Moloney murine sarcoma virus as evident in a transplantable epithelioid neoplasm of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194654"} {"pmid": "4194655", "title": "Transformation and virus production in normal rat thymus cells and those infected with Moloney leukemia virus.", "content": "Transformation and virus production in normal rat thymus cells and those infected with Moloney leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194655"} {"pmid": "4194657", "title": "Immunoferritin and immunofluorescent studies with Epstein-Barr virus and herpes simplex virus by use of human sera and hyperimmune rabbit sera.", "content": "Immunoferritin and immunofluorescent studies with Epstein-Barr virus and herpes simplex virus by use of human sera and hyperimmune rabbit sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194657"} {"pmid": "4194656", "title": "Characteristics of a new inbred strain of mice (PBA) with a high tumor incidence: preliminary report.", "content": "Characteristics of a new inbred strain of mice (PBA) with a high tumor incidence: preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194656"} {"pmid": "4194658", "title": "Studies on the antigenic activities of yeasts. V. Effect of alpha-mannosidase digestion on the immunochemical properties of the mannan of Saccharomyces cerevisiae.", "content": "Studies on the antigenic activities of yeasts. V. Effect of alpha-mannosidase digestion on the immunochemical properties of the mannan of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194658"} {"pmid": "4194659", "title": "Pituitary radiotherapy.", "content": "Pituitary radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194659"} {"pmid": "4194660", "title": "A theory of self-nonself discrimination.", "content": "A theory of self-nonself discrimination. 1) Induction of humoral antibody formation involves the obligatory recognition of two determinants on an antigen, one by the receptor antibody of the antigen-sensitive cell and the other by carrier antibody (associative interaction). 2) Paralysis of antibody formation involves the obligatory recognition of only one determinant by the receptor antibody of the antigen-sensitive cell; that is, a nonimmunogenic molecule (a hapten) can paralyze antigen-sensitive cells. 3) There is competition between paralysis and induction at the level of the antigen-sensitive cell. 4) The mechanisms of low- and high-zone paralysis, and maintenance of the unresponsive state, are identical. 5) High-zone paralysis occurs when both the carrier antibody and the receptor antibody are saturated, so that associated interactions cannot take place. 6) The mechanisms of paralysis and induction for the carrier-antigen-sensitive cell are identical to those for the humoral-antigen-sensitive cell. 7) The formation of carrier-antigen-sensitive cells is thymus-dependent, whereas humoral-antigen-sensitive cells are derived from bone marrow. Since carrier antibody is required for induction, all antigens are thymus-dependent. 8) The interaction of antigen with the receptor antibody on an antigen-sensitive cell results in a conformational change in an invariant region of the receptor and consequently paralyzes the cell. As the receptor is probably identical to the induced antibody, all antibody molecules are expected to be able to undergo a conformational change on binding a hapten. The obligatory associated recognition by way of carrier antibody (inductive signal) involves a conformational change in the carrier antibody, leading to a second signal to the antigen-sensitive cell. 9) The foregoing requirements provide an explanation for self-nonself discrimination. Tolerance to self-antigens involves a specific deletion in the activity of both the humoral- and the carrier-antigen-sensitive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194660"} {"pmid": "4194661", "title": "Neoplasia of the solitary kidney.", "content": "Neoplasia of the solitary kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194661"} {"pmid": "4194664", "title": "The antibody deficiency syndrome--clinical considerations.", "content": "The antibody deficiency syndrome--clinical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194664"} {"pmid": "4194662", "title": "The place of cryoprostatectomy.", "content": "The place of cryoprostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194662"} {"pmid": "4194663", "title": "The newer anti-allergic agents.", "content": "The newer anti-allergic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194663"} {"pmid": "4194667", "title": "The distribution of characters considered to be microforms of cleft lip and-or palate in a population of normal 18-21 year old subjects.", "content": "The distribution of characters considered to be microforms of cleft lip and-or palate in a population of normal 18-21 year old subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194667"} {"pmid": "4194668", "title": "An attempt to treat children with Pierre Robin syndrome orthopaedically.", "content": "An attempt to treat children with Pierre Robin syndrome orthopaedically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194668"} {"pmid": "4194669", "title": "Surgical treatment of palmar and plantar keratosis.", "content": "Surgical treatment of palmar and plantar keratosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194669"} {"pmid": "4194670", "title": "Pseudohermaphroditism.", "content": "Pseudohermaphroditism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194670"} {"pmid": "4194671", "title": "Hypospadias and a new method of its surgical treatment.", "content": "Hypospadias and a new method of its surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194671"} {"pmid": "4194672", "title": "One-stage operation for hypospadias.", "content": "One-stage operation for hypospadias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194672"} {"pmid": "4194673", "title": "Contribution to the re-hydration of freeze-dried grafts. I. Re-hydration of rib bone grafts (short report).", "content": "Contribution to the re-hydration of freeze-dried grafts. I. Re-hydration of rib bone grafts (short report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194673"} {"pmid": "4194674", "title": "The revascularization of a free skin autograft.", "content": "The revascularization of a free skin autograft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194674"} {"pmid": "4194675", "title": "Experiment with many-layered skin grafts.", "content": "Experiment with many-layered skin grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194675"} {"pmid": "4194676", "title": "The surgical treatment of skin damaged by radiation.", "content": "The surgical treatment of skin damaged by radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194676"} {"pmid": "4194677", "title": "The viability of cartilage transplants.", "content": "The viability of cartilage transplants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194677"} {"pmid": "4194679", "title": "A histochemical study on the histogenesis of the mixed tumours of the human salivary glands.", "content": "A histochemical study on the histogenesis of the mixed tumours of the human salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194679"} {"pmid": "4194684", "title": "Phage-like particles from a lysogenic Thermomonospora.", "content": "Phage-like particles from a lysogenic Thermomonospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194684"} {"pmid": "4194685", "title": "The action of visible radiation on the formation and properties of Saccharomyces ascospores.", "content": "The action of visible radiation on the formation and properties of Saccharomyces ascospores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194685"} {"pmid": "4194686", "title": "Enhancing effect of DEAE-Dextran on inclusion counts of an ovine Chlamydia (Bedsonia) in cell culture.", "content": "Enhancing effect of DEAE-Dextran on inclusion counts of an ovine Chlamydia (Bedsonia) in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194686"} {"pmid": "4194687", "title": "Starch-iodide as a stain for peroxidases.", "content": "Starch-iodide as a stain for peroxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194687"} {"pmid": "4194690", "title": "Combined treatment of parkinsonism with L-dopa and amantadine.", "content": "Combined treatment of parkinsonism with L-dopa and amantadine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194690"} {"pmid": "4194689", "title": "Electron microscopical and immunological observations on the serum-hepatitis (S.H.) antigen in primary biliary cirrhosis.", "content": "Electron microscopical and immunological observations on the serum-hepatitis (S.H.) antigen in primary biliary cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194689"} {"pmid": "4194691", "title": "Autologous transfusions in uraemic patients.", "content": "Autologous transfusions in uraemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194691"} {"pmid": "4194692", "title": "\"Free\" iron loss in atrophic gastritis, post-gastrectomy states, and adult coeliac disease.", "content": "\"Free\" iron loss in atrophic gastritis, post-gastrectomy states, and adult coeliac disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194692"} {"pmid": "4194693", "title": "Urinary steroid-excretion patterns after acute myocardial infarction.", "content": "Urinary steroid-excretion patterns after acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194693"} {"pmid": "4194694", "title": "Long-term hepatic support by intermittent multi-species liver perfusions.", "content": "Long-term hepatic support by intermittent multi-species liver perfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194694"} {"pmid": "4194695", "title": "Detection of thrombosis with iodine-125 fibrinogen. Data reassessed.", "content": "Detection of thrombosis with iodine-125 fibrinogen. Data reassessed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194695"} {"pmid": "4194696", "title": "Control of tuberculosis.", "content": "Control of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194696"} {"pmid": "4194697", "title": "Liver disease in ulcerative colitis.", "content": "Liver disease in ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194697"} {"pmid": "4194698", "title": "Direction for social science.", "content": "Direction for social science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194698"} {"pmid": "4194699", "title": "Screening for breast and gynaecological lesions.", "content": "Screening for breast and gynaecological lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194699"} {"pmid": "4194700", "title": "Cholera on the Caspian.", "content": "Cholera on the Caspian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194700"} {"pmid": "4194701", "title": "Design of skin flaps.", "content": "Design of skin flaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194701"} {"pmid": "4194702", "title": "Septic thrombophlebitis and venous cannulas.", "content": "Septic thrombophlebitis and venous cannulas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194702"} {"pmid": "4194703", "title": "Screening for breast cancer.", "content": "Screening for breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194703"} {"pmid": "4194705", "title": "Child care in Czechoslovakia.", "content": "Child care in Czechoslovakia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194705"} {"pmid": "4194704", "title": "Screening for breast and gynaecological lesions.", "content": "Screening for breast and gynaecological lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194704"} {"pmid": "4194706", "title": "Abortion analysis.", "content": "Abortion analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194706"} {"pmid": "4194707", "title": "\"Central\" venous pressure.", "content": "\"Central\" venous pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194707"} {"pmid": "4194708", "title": "Carrageenan and the human gut.", "content": "Carrageenan and the human gut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194708"} {"pmid": "4194709", "title": "Carrageenan: effects in animals.", "content": "Carrageenan: effects in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194709"} {"pmid": "4194710", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194710"} {"pmid": "4194711", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194711"} {"pmid": "4194712", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194712"} {"pmid": "4194713", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194713"} {"pmid": "4194714", "title": "Sterilisation.", "content": "Sterilisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194714"} {"pmid": "4194715", "title": "Burkitt lymphoma and malaria.", "content": "Burkitt lymphoma and malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194715"} {"pmid": "4194716", "title": "Hepatitis-Associated antigen.", "content": "Hepatitis-Associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194716"} {"pmid": "4194717", "title": "Streptokinase for pulmonary embolism.", "content": "Streptokinase for pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194717"} {"pmid": "4194718", "title": "Streptokinase for pulmonary embolism.", "content": "Streptokinase for pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194718"} {"pmid": "4194719", "title": "Intracranial venous thrombosis complicating oral contraception.", "content": "Intracranial venous thrombosis complicating oral contraception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194719"} {"pmid": "4194720", "title": "Prevention of venous thrombosis.", "content": "Prevention of venous thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194720"} {"pmid": "4194721", "title": "Animal sources of Escherichia coli in food.", "content": "Animal sources of Escherichia coli in food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194721"} {"pmid": "4194722", "title": "Spoons and dip-slides.", "content": "Spoons and dip-slides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194722"} {"pmid": "4194723", "title": "Swallowed neonatal endotracheal tube.", "content": "Swallowed neonatal endotracheal tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194723"} {"pmid": "4194724", "title": "Plasma-catecholamine estimations.", "content": "Plasma-catecholamine estimations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194724"} {"pmid": "4194725", "title": "Glucagon and the heart.", "content": "Glucagon and the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194725"} {"pmid": "4194726", "title": "Coxsackie myocarditis of the newborn.", "content": "Coxsackie myocarditis of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194726"} {"pmid": "4194727", "title": "Comparsion of antihypertensive agents.", "content": "Comparsion of antihypertensive agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194727"} {"pmid": "4194728", "title": "Dialysis circuit monitors.", "content": "Dialysis circuit monitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194728"} {"pmid": "4194730", "title": "Carbenicillin in renal failure.", "content": "Carbenicillin in renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194730"} {"pmid": "4194729", "title": "Serum-enzymes in dialysis patients.", "content": "Serum-enzymes in dialysis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194729"} {"pmid": "4194731", "title": "Carbenicillin in renal failure.", "content": "Carbenicillin in renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194731"} {"pmid": "4194732", "title": "48-hour kidney storage.", "content": "48-hour kidney storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194732"} {"pmid": "4194733", "title": "Sputum viscosity in cystic fibrosis.", "content": "Sputum viscosity in cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194733"} {"pmid": "4194735", "title": "Etiology of Crohn's disease.", "content": "Etiology of Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194735"} {"pmid": "4194734", "title": "Diabetes, diabetic angiopathy, and growth hormone.", "content": "Diabetes, diabetic angiopathy, and growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194734"} {"pmid": "4194736", "title": "Atypical reactions to bromsulphthalein (B.S.P.).", "content": "Atypical reactions to bromsulphthalein (B.S.P.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194736"} {"pmid": "4194738", "title": "Stereostethoscope.", "content": "Stereostethoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194738"} {"pmid": "4194737", "title": "Bedside diagnosis of the myasthenic syndrome.", "content": "Bedside diagnosis of the myasthenic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194737"} {"pmid": "4194739", "title": "Birth control and sex ratio.", "content": "Birth control and sex ratio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194739"} {"pmid": "4194740", "title": "Anticonvulsant drugs and chromosomes.", "content": "Anticonvulsant drugs and chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194740"} {"pmid": "4194741", "title": "Cytostatic drugs and inflammation.", "content": "Cytostatic drugs and inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194741"} {"pmid": "4194742", "title": "James Harkness Margerison, M.B. St. And.", "content": "James Harkness Margerison, M.B. St. And.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194742"} {"pmid": "4194743", "title": "John Marshall, M.C., T.D., M.B. Glasg., F.R.C.P.G., D.O.M.S.", "content": "John Marshall, M.C., T.D., M.B. Glasg., F.R.C.P.G., D.O.M.S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194743"} {"pmid": "4194753", "title": "Some considerations dealing with the role of the graft in the pathology of clinical transplantation.", "content": "Some considerations dealing with the role of the graft in the pathology of clinical transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194753"} {"pmid": "4194752", "title": "Genetical aspects in experimental induction of the cleft palate by cortisone in inbred strains of mice. A study of the segregation of the cleft palate and some of the genetically conditioned markers.", "content": "Genetical aspects in experimental induction of the cleft palate by cortisone in inbred strains of mice. A study of the segregation of the cleft palate and some of the genetically conditioned markers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194752"} {"pmid": "4194754", "title": "Epidemiologic studies on congenital malformations. Critical review and new conceptions.", "content": "Epidemiologic studies on congenital malformations. Critical review and new conceptions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194754"} {"pmid": "4194755", "title": "Contribution to the etiopathology of the cleft lip and palate.", "content": "Contribution to the etiopathology of the cleft lip and palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194755"} {"pmid": "4194756", "title": "Application of tube pedicle flap for covering defects of the conjunctival sac.", "content": "Application of tube pedicle flap for covering defects of the conjunctival sac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194756"} {"pmid": "4194757", "title": "Classification of scarred neck contractures and their surgical therapy by methods of local plastic operation.", "content": "Classification of scarred neck contractures and their surgical therapy by methods of local plastic operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194757"} {"pmid": "4194758", "title": "Treatment of hypospadias.", "content": "Treatment of hypospadias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194758"} {"pmid": "4194761", "title": "Proteinaceous cysts of the ciliary epithelium. II. Their occurrence in nonmyelomatous hypergammaglobulinemic conditions.", "content": "Proteinaceous cysts of the ciliary epithelium. II. Their occurrence in nonmyelomatous hypergammaglobulinemic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194761"} {"pmid": "4194762", "title": "Dendritic fields of the retinal ganglion cells in the cat.", "content": "Dendritic fields of the retinal ganglion cells in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194762"} {"pmid": "4194766", "title": "Continued studies on the axonal transport of nerve proteins to muscle.", "content": "Continued studies on the axonal transport of nerve proteins to muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194766"} {"pmid": "4194767", "title": "The effect of hydrocortisone on immunoglobulin metabolism.", "content": "The effect of hydrocortisone on immunoglobulin metabolism. The serum concentration of all subclasses of IgG (gamma(2)A, gamma(2)B, and gamma(1)) as well as IgA and IgM were reduced in normal and low pathogen mice receiving hydrocortisone acetate. Turnover studies using (131)I-labeled gamma(2)A subclass of IgG demonstrated that high dose corticosteroids cause a significantly shortened survival (increased catabolic rate) which contributes to the observed hypogammaglobulinemia. This increase in fractional catabolism is not due to excess loss in the urine or stool but reflects an increase in endogenous catabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194767"} {"pmid": "4194768", "title": "Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man.", "content": "Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man. To explore the relation between androgens and prostatic hypertrophy in man, the concentrations of testosterone, dihydrotestosterone, and androstenedione and the rate of conversion of testosterone to dihydrotestosterone have been measured in normal and hypertrophic prostate tissue. First, a double isotope derivative technique was adapted for the measurement of tissue androgen content in 15 normal and 10 hypertrophic prostates. Although there was no significant difference in the content of androstenedione and testosterone between the two types of tissue, the content of dihydrotestosterone was significantly greater in the hypertrophic tissue (0.60 +/-0.10 mug/100 g) than in the normal glands (0.13 +/-0.05 mug/100 g). Second, a regional study was performed in three normal prostates and four glands with early hypertrophy, and it was demonstrated that the dihydrotestosterone content was two and three fold greater in the periurethral area where prostatic hypertrophy usually commences than in the outer regions of the gland. Finally, the rate of conversion of testosterone to dihydrotestosterone has been measured under standardized conditions in tissue slices from 4 normal and 20 hypertrophic prostates. There was no significant difference in the rate of dihydrotestosterone formation between the two types of gland (6.0 +/-0.8 and 7.8 +/-0.5 mumumoles/15 mg of tissue per hr). While the mechanism by which dihydrotestosterone accumulation occurs remains unexplained, it is possible that the local accumulation of dihydrotestosterone may be involved in the pathogenesis of prostatic hypertrophy in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194768"} {"pmid": "4194769", "title": "Dihydrotestosterone in prostatic hypertrophy. II. The formation and content of dihydrotestosterone in the hypertrophic canine prostate and the effect of dihydrotestosterone on prostate growth in the dog.", "content": "Dihydrotestosterone in prostatic hypertrophy. II. The formation and content of dihydrotestosterone in the hypertrophic canine prostate and the effect of dihydrotestosterone on prostate growth in the dog. Three types of studies have been performed in immature, mature, and hypertrophic prostate glands of the dog. First, the concentrations of testosterone and dihydrotestosterone have been measured in the three types of gland. Dihydrotestosterone was the predominant hormone recovered in all prostates studied and was present in approximately five times higher concentration in the hypertrophic as compared to the other types of dog prostate. Second, pharmacological doses of dihydrotestosterone were administered to castrated dogs for 9 months and resulted in a distinct acceleration of prostatic growth as compared to testosterone treatment. Third, the rates of formation and degradation of dihydrotestosterone were measured in normal and hypertrophic tissue and were found to be essentially the same. These observations suggest that dihydrotestosterone accumulation may be causally linked to the development of canine prostatic hypertrophy. However, the mechanism by which dihydrotestosterone accumulates in the prostate remains to be determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194769"} {"pmid": "4194773", "title": "Immunoglobulin allotypic determinants on rabbit lymphocytes.", "content": "Immunoglobulin allotypic determinants on rabbit lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194773"} {"pmid": "4194772", "title": "Promising trends in neuroscience.", "content": "Promising trends in neuroscience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194772"} {"pmid": "4194776", "title": "Electromechanical correlations in the mammalian heart muscle.", "content": "Electromechanical correlations in the mammalian heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194776"} {"pmid": "4194787", "title": "Behaviour of mast cells in the skin of mice treated with benzpyrene.", "content": "Behaviour of mast cells in the skin of mice treated with benzpyrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194787"} {"pmid": "4194788", "title": "Biological variables associated with mothers of children affected with the G1-trisomy syndrome. (Down's syndrome).", "content": "Biological variables associated with mothers of children affected with the G1-trisomy syndrome. (Down's syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194788"} {"pmid": "4194789", "title": "Multiplication of fowlpox virus in chicken embryo fibroblastic cell cultures.", "content": "Multiplication of fowlpox virus in chicken embryo fibroblastic cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194789"} {"pmid": "4194796", "title": "Cross-reactions between human and animal plasma proteins. II. The influence of structural and functional factors.", "content": "Cross-reactions between human and animal plasma proteins. II. The influence of structural and functional factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194796"} {"pmid": "4194798", "title": "Observations on the immune globulin levels of neonatal calves and their relationship to disease.", "content": "Observations on the immune globulin levels of neonatal calves and their relationship to disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194798"} {"pmid": "4194797", "title": "Effects of Escherichia coli on germ-free and gnotobiotic pigs. II. Serum proteins and antibodies.", "content": "Effects of Escherichia coli on germ-free and gnotobiotic pigs. II. Serum proteins and antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194797"} {"pmid": "4194799", "title": "Hyaline arteriolosclerosis in wild animals.", "content": "Hyaline arteriolosclerosis in wild animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194799"} {"pmid": "4194800", "title": "Effect of histomoniasis on the serum proteins of the fowl.", "content": "Effect of histomoniasis on the serum proteins of the fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194800"} {"pmid": "4194801", "title": "Microprobe analysis of Protargol stain deposition in two protozoa.", "content": "Microprobe analysis of Protargol stain deposition in two protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194801"} {"pmid": "4194810", "title": "Elongated structures present in cells infected with influenza viruses.", "content": "Elongated structures present in cells infected with influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194810"} {"pmid": "4194813", "title": "A research standard for human serum immunoglobulins IgG, IgA and IgM.", "content": "A research standard for human serum immunoglobulins IgG, IgA and IgM. A pooled human serum, partly diluted, has been distributed into ampoules and freeze-dried in several batches. The freeze-dried material has been examined in an international collaborative assay and certain properties have also been estimated in individual laboratories.On the basis of these tests this material was considered to be suitable for use as a standard for the estimation of IgG, IgA and IgM for clinical purposes using the single-radial-diffusion or similar techniques. Greater uniformity of results than is obtained at present should be achieved if this material were in general use.Estimates of immunoglobulins from different laboratories using this material as a standard showed small but significant variability. This variability was probably related to the heterogeneity of immunoglobulins and of antisera, and it limits the precision of immunoglobulin estimations by techniques at present in use.Batches of this material have been distributed to various centres. 67/68 has been established as the British research standard for human serum immunoglobulins IgG, IgA and IgM for which the unit of potency is defined as the activity present in 0.8147 mg of dry powder. The average activity per ampoule of 67/86 is 100 units of IgG, IgA and IgM. The average activities of other related preparations have been estimated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194813"} {"pmid": "4194814", "title": "Lack of seasonal variation in protein-bound iodine.", "content": "Lack of seasonal variation in protein-bound iodine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194814"} {"pmid": "4194816", "title": "Iodine metabolism in autoimmune thyroiditis.", "content": "Iodine metabolism in autoimmune thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194816"} {"pmid": "4194818", "title": "Indications for prostatectomy.", "content": "Indications for prostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194818"} {"pmid": "4194820", "title": "Studies on cytophilic antibodies. A mouse serum \"antibody\" having an affinity for macrophages and fast alpha-globulin mobility.", "content": "Studies on cytophilic antibodies. A mouse serum \"antibody\" having an affinity for macrophages and fast alpha-globulin mobility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194820"} {"pmid": "4194821", "title": "Chemical linkage of polycyclic hydrocarbons to deoxyribonucleic acids and polynucleotides in aqueous solution and in a buffer-ethanol solvent system.", "content": "Chemical linkage of polycyclic hydrocarbons to deoxyribonucleic acids and polynucleotides in aqueous solution and in a buffer-ethanol solvent system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194821"} {"pmid": "4194826", "title": "Characteristics of antigenic determinants of intact cell surfaces.", "content": "Characteristics of antigenic determinants of intact cell surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194826"} {"pmid": "4194825", "title": "Volume changes accompanying the antibody-antigen reaction.", "content": "Volume changes accompanying the antibody-antigen reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194825"} {"pmid": "4194824", "title": "Ultraviolet absorbing dyes as histochemical reagents.", "content": "Ultraviolet absorbing dyes as histochemical reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194824"} {"pmid": "4194827", "title": "Juvenile rheumatoid arthritis--a serologic survey of 200 consecutive patients.", "content": "Juvenile rheumatoid arthritis--a serologic survey of 200 consecutive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194827"} {"pmid": "4194830", "title": "Spontaneous renal carcinoma in a New Zealand white rabbit.", "content": "Spontaneous renal carcinoma in a New Zealand white rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194830"} {"pmid": "4194828", "title": "Appearance and distribution of ectromelia virus inclusion bodies in experimentally infected mice.", "content": "Appearance and distribution of ectromelia virus inclusion bodies in experimentally infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194828"} {"pmid": "4194831", "title": "Two ways to protein.", "content": "Two ways to protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194831"} {"pmid": "4194832", "title": "Measles.", "content": "Measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194832"} {"pmid": "4194833", "title": "Familial metaphyseal dysplasia.", "content": "Familial metaphyseal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194833"} {"pmid": "4194834", "title": "Blood-groups and nasopharyngeal carcinoma.", "content": "Blood-groups and nasopharyngeal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194834"} {"pmid": "4194835", "title": "Prevention of venous thrombosis.", "content": "Prevention of venous thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194835"} {"pmid": "4194837", "title": "Drastic cures for obesity.", "content": "Drastic cures for obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194837"} {"pmid": "4194838", "title": "Side-effects of insulin contaminating commercial glucagon.", "content": "Side-effects of insulin contaminating commercial glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194838"} {"pmid": "4194839", "title": "Smoking, air pollution, bronchitis, and population mobility.", "content": "Smoking, air pollution, bronchitis, and population mobility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194839"} {"pmid": "4194840", "title": "Hydroxylysinuria.", "content": "Hydroxylysinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194840"} {"pmid": "4194841", "title": "Cryotherapy in head and neck cancer.", "content": "Cryotherapy in head and neck cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194841"} {"pmid": "4194842", "title": "Early diagnosis of lung cancer by cytology.", "content": "Early diagnosis of lung cancer by cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194842"} {"pmid": "4194843", "title": "Electrophoresis and immunodiffusion techniques on cellulose acetate membrane.", "content": "Electrophoresis and immunodiffusion techniques on cellulose acetate membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194843"} {"pmid": "4194857", "title": "Some morphological features of bluetongue virus.", "content": "Some morphological features of bluetongue virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194857"} {"pmid": "4194858", "title": "Diagnosis of hyperthyroidism. Statistical evaluation of laboratory and clinical criteria.", "content": "Diagnosis of hyperthyroidism. Statistical evaluation of laboratory and clinical criteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194858"} {"pmid": "4194859", "title": "Simple method for quantitive densitometry of polyacrylamide gels using fast green.", "content": "Simple method for quantitive densitometry of polyacrylamide gels using fast green.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194859"} {"pmid": "4194860", "title": "The genetically determined binding of alcian blue by a minor fraction of yeast cell walls.", "content": "The genetically determined binding of alcian blue by a minor fraction of yeast cell walls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194860"} {"pmid": "4194861", "title": "The dissociation in vitro of the alpha- and beta-lipoprotein components of human and rat very low density lipoproteins.", "content": "The dissociation in vitro of the alpha- and beta-lipoprotein components of human and rat very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194861"} {"pmid": "4194862", "title": "The wheezing patient. Problems in the differential diagnosis of allergic bronchial asthma.", "content": "The wheezing patient. Problems in the differential diagnosis of allergic bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194862"} {"pmid": "4194863", "title": "Selecting content in medical-surgical nursing for the associate degree nursing program.", "content": "Selecting content in medical-surgical nursing for the associate degree nursing program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194863"} {"pmid": "4194865", "title": "Selective gamma-g globulin deficiencies in patients with recurrent pyogenic infections.", "content": "Selective gamma-g globulin deficiencies in patients with recurrent pyogenic infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194865"} {"pmid": "4194867", "title": "Synthesis of immunoglobulin heavy and light chains by the free ribosomes of a mouse plasma cell tumor.", "content": "Synthesis of immunoglobulin heavy and light chains by the free ribosomes of a mouse plasma cell tumor. Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell-free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194867"} {"pmid": "4194869", "title": "Thyroidal iodine and proteins in autoimmune thyroiditis.", "content": "Thyroidal iodine and proteins in autoimmune thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194869"} {"pmid": "4194868", "title": "Implications of heavy chain disease protein sequences for multiple gene theories of immunoglobulin synthesis.", "content": "Implications of heavy chain disease protein sequences for multiple gene theories of immunoglobulin synthesis. The sequence of the amino-terminal 34 amino acids of gamma-heavy chain disease (gamma-HCD) protein Hi is homologous with the amino-terminal region of immunoglobulin heavy chains. gamma-heavy chain disease is smaller than a normal gamma-chain, but has the carboxy-terminal composition expected for gamma-chains and must, therefore, contain an internal deletion. Comparison of the Hi sequence with that of gamma-heavy chain disease Zu, which also has an internal deletion, indicates that the site of internal deletion is not a constant characteristic of gamma-heavy chain disease proteins. Heavy chains can be assigned to subgroups on the basis of variable region sequences. The variable regions of Hi and one other protein differ significantly from those determined for other heavy chains, and these two proteins are assigned to a new heavy chain variable region subgroup, V(HIV). It has been suggested that single immunoglobulin heavy chains are the products of two separate structural genes and that variable region genetic information is translocated and integrated into common region information. These multiple gene theories make no prediction as to whether DNA or RNA is translocated. gamma-heavy chain disease proteins provide unique information that indicates that if translocation is required for the production of immunoglobulin heavy chains, it is DNA, not RNA, that is translocated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194868"} {"pmid": "4194870", "title": "The serum proteins identified by means of the Laurell crossed electrophoresis.", "content": "The serum proteins identified by means of the Laurell crossed electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194870"} {"pmid": "4194871", "title": "Metabolism of bence jones proteins in non-myeloma patients with normal renal function.", "content": "Metabolism of bence jones proteins in non-myeloma patients with normal renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194871"} {"pmid": "4194878", "title": "Electron microscope studies of sperm incorporation into the golden hamster egg.", "content": "Electron microscope studies of sperm incorporation into the golden hamster egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194878"} {"pmid": "4194880", "title": "Immunoglobulin E-mediated respiratory responses of subhuman primates. Reproducibility and effect of certain pharmacologic agents.", "content": "Immunoglobulin E-mediated respiratory responses of subhuman primates. Reproducibility and effect of certain pharmacologic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194880"} {"pmid": "4194882", "title": "Pulmonary responses to inhaled particles. Role of vasoactive substances.", "content": "Pulmonary responses to inhaled particles. Role of vasoactive substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194882"} {"pmid": "4194879", "title": "Evaluation of laboratory methods for detecting acute TRIC agent infection.", "content": "Evaluation of laboratory methods for detecting acute TRIC agent infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194879"} {"pmid": "4194885", "title": "Metabolic activities of thyroid glands from tapazole treated rats.", "content": "Metabolic activities of thyroid glands from tapazole treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194885"} {"pmid": "4194884", "title": "Evaluation of the triiodothyronine suppression test in the treatment of Graves' disease.", "content": "Evaluation of the triiodothyronine suppression test in the treatment of Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194884"} {"pmid": "4194886", "title": "A whole-mount cholinesterase technique for demonstrating corneal nerves: observations in the albino rabbit.", "content": "A whole-mount cholinesterase technique for demonstrating corneal nerves: observations in the albino rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194886"} {"pmid": "4194887", "title": "Further experimental studies of dynamic propositions in psychoanalysis. On the function and meaning of regressive thinking.", "content": "Further experimental studies of dynamic propositions in psychoanalysis. On the function and meaning of regressive thinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194887"} {"pmid": "4194888", "title": "The development of the child's sense of his sexual identity.", "content": "The development of the child's sense of his sexual identity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194888"} {"pmid": "4194890", "title": "The extent of ischemic damage in the myocardium of the cat after permanent and temporary coronary occlusion.", "content": "The extent of ischemic damage in the myocardium of the cat after permanent and temporary coronary occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194890"} {"pmid": "4194889", "title": "Effect of water pressure irrigation on stainable material on the teeth.", "content": "Effect of water pressure irrigation on stainable material on the teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194889"} {"pmid": "4194891", "title": "Palliative esophagogastrostomy for inoperable carcinoma of the esophagogastric junction.", "content": "Palliative esophagogastrostomy for inoperable carcinoma of the esophagogastric junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194891"} {"pmid": "4194892", "title": "Plasma protein changes in mild thermal trauma.", "content": "Plasma protein changes in mild thermal trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194892"} {"pmid": "4194900", "title": "Pick's disease with compound intraneuronal inclusion bodies.", "content": "Pick's disease with compound intraneuronal inclusion bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194900"} {"pmid": "4194901", "title": "Benign fibro-osseous lesions of the mandible and maxilla. A review of 35 cases.", "content": "Benign fibro-osseous lesions of the mandible and maxilla. A review of 35 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194901"} {"pmid": "4194902", "title": "Mesonephroma ovarii (hypernephroid carcinoma). Light microscopic and ultrastructural study of a case.", "content": "Mesonephroma ovarii (hypernephroid carcinoma). Light microscopic and ultrastructural study of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194902"} {"pmid": "4194895", "title": "Adult-type Gaucher's disease: a secondary disorder of iron metabolism.", "content": "Adult-type Gaucher's disease: a secondary disorder of iron metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194895"} {"pmid": "4194907", "title": "A study of the late form (type Lundborg) of progressive myoclonic epilepsy.", "content": "A study of the late form (type Lundborg) of progressive myoclonic epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194907"} {"pmid": "4194910", "title": "Discharge of the terminally-ill patient.", "content": "Discharge of the terminally-ill patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194910"} {"pmid": "4194914", "title": "Astrocytes in formalin-fixed paraffin sections. A new modification of Cajal's technic and comparison with the hematoxylin and eosin method.", "content": "Astrocytes in formalin-fixed paraffin sections. A new modification of Cajal's technic and comparison with the hematoxylin and eosin method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194914"} {"pmid": "4194906", "title": "Guinea pig ovary and testis: demonstration of common gonad specific antigens in the ovary and testis.", "content": "Guinea pig ovary and testis: demonstration of common gonad specific antigens in the ovary and testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194906"} {"pmid": "4194917", "title": "Myocardial necrosis induced by isoproterenol in rats. Changes in serum protein, lipoprotein, lipids and glucose during active necrosis and repair in arteriosclerotic and nonarteriosclerotic animals.", "content": "Myocardial necrosis induced by isoproterenol in rats. Changes in serum protein, lipoprotein, lipids and glucose during active necrosis and repair in arteriosclerotic and nonarteriosclerotic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194917"} {"pmid": "4194908", "title": "The judgment of vowel quality.", "content": "The judgment of vowel quality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194908"} {"pmid": "4194912", "title": "Localization of Treponema pallidum immobilizing antibody in human immunoglobulins.", "content": "Localization of Treponema pallidum immobilizing antibody in human immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194912"} {"pmid": "4194926", "title": "The management of terminal carcinoma with oral potassium permanganate.", "content": "The management of terminal carcinoma with oral potassium permanganate. Oral potassium permanganate has been used in the management of terminal carcinoma in three patients. Symptomatic improvement occurred in all three, with elimination of oral foetor in one patient and diminished requirement of analgesics in the other two. The mental state of each patient was improved and normal activities were resumed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194926"} {"pmid": "4194925", "title": "Excretion of immunoglobulins in Burkitt's lymphoma.", "content": "Excretion of immunoglobulins in Burkitt's lymphoma. IgM was detected in the urines of 4 out of 17 patients with Burkitt's lymphoma. This IgM emerged from Sephadex G 200 column in two different peaks strongly suggesting sub-units of the intact molecule. IgM was not detected in any of the control urines. The total protein excreted in the urine of Burkitt's lymphoma patients is higher than in controls and may be due to renal involvement. Intact IgA and IgG as well as fragments of IgG were present in the urines of all Burkitt patients as well as in controls. Six of 16 Burkitt's lymphoma patients had reduced serum levels of IgG. Four of these also had reduced serum IgM. The low mean concentration of serum IgM confirms our previous studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194925"} {"pmid": "4194927", "title": "The effect of tumour growth on immune competence. A study of DMBA mammary carcinogenesis in the rat.", "content": "The effect of tumour growth on immune competence. A study of DMBA mammary carcinogenesis in the rat. Circulating antibody response to flagella antigen has been measured in three groups of Sprague-Dawley rats after feeding with 7.12.DMBA in an attempt to differentiate carcinogen and tumour growth as causative agents in the depression of immune response seen in these animals. DMBA fed female rats developing tumours had progressive depression of both primary and secondary response as compared to control animals, and 7S and 19S antibody fractions were equally affected. Removal of tumours did not result in recovery of response. Attempts to prevent tumour development by mammectomy after DMBA feeding were unsuccessful, but the similar number of tumours found in this group was associated with an equal degree of antibody depression to that seen in the first experiment. Male animals fed DMBA did not develop malignant tumours, and showed no depression of immune response. Results suggest that tumour development plays a part in the depression of circulating antibody response seen in these animals, but that it is not directly related to the number of tumours, and is not reversible by tumour excision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194927"} {"pmid": "4194928", "title": "A staining technique to demonstrate erythrocyte refractile bodies in cat blood.", "content": "A staining technique to demonstrate erythrocyte refractile bodies in cat blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194928"} {"pmid": "4194929", "title": "The effect of haemoglobin on the detection of immunoglobulins in calf sera.", "content": "The effect of haemoglobin on the detection of immunoglobulins in calf sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194929"} {"pmid": "4194930", "title": "Preparation and purification of horse antihuman lymphocyte globulin (ALG).", "content": "Preparation and purification of horse antihuman lymphocyte globulin (ALG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194930"} {"pmid": "4194933", "title": "Palliative treatment of dysphagia in advanced carcinoma of stomach.", "content": "Palliative treatment of dysphagia in advanced carcinoma of stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194933"} {"pmid": "4194934", "title": "Cardiac transplantation in man. 8. Survival and function.", "content": "Cardiac transplantation in man. 8. Survival and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194934"} {"pmid": "4194935", "title": "Controlled trial of cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood.", "content": "Controlled trial of cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194935"} {"pmid": "4194936", "title": "Ovulation stimulation. Problems of prediction of response to gonadotrophins.", "content": "Ovulation stimulation. Problems of prediction of response to gonadotrophins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194936"} {"pmid": "4194937", "title": "Coronary prognostic index for predicting survival after recovery from acute myocardial infarction.", "content": "Coronary prognostic index for predicting survival after recovery from acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194937"} {"pmid": "4194938", "title": "Hypercholesterolaemia in borderline hypothyroidism. Stage of premyxoedema.", "content": "Hypercholesterolaemia in borderline hypothyroidism. Stage of premyxoedema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194938"} {"pmid": "4194939", "title": "Iron therapy in patients on maintenance haemodialysis.", "content": "Iron therapy in patients on maintenance haemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194939"} {"pmid": "4194941", "title": "Further observations on Kveim test in Crohn's disease.", "content": "Further observations on Kveim test in Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194941"} {"pmid": "4194940", "title": "Hyperaluminaemia from aluminum resins in renal failure.", "content": "Hyperaluminaemia from aluminum resins in renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194940"} {"pmid": "4194943", "title": "Subacute sclerosing panencephalitis: a zoonosis following aberrant measles.", "content": "Subacute sclerosing panencephalitis: a zoonosis following aberrant measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194943"} {"pmid": "4194942", "title": "Further assessment of the venous-compression test in hyperparathyroidism.", "content": "Further assessment of the venous-compression test in hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194942"} {"pmid": "4194947", "title": "Immunosuppression in nephritis.", "content": "Immunosuppression in nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194947"} {"pmid": "4194944", "title": "Semiautomatic electrocardiographic monitoring.", "content": "Semiautomatic electrocardiographic monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194944"} {"pmid": "4194946", "title": "Laryngeal strombomicroscope.", "content": "Laryngeal strombomicroscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194946"} {"pmid": "4194945", "title": "Pneumatic intermittent-compression legging simulating calf-muscle pump.", "content": "Pneumatic intermittent-compression legging simulating calf-muscle pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194945"} {"pmid": "4194948", "title": "Treatment of infertility.", "content": "Treatment of infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194948"} {"pmid": "4194950", "title": "Epidemiology of gallstone disease.", "content": "Epidemiology of gallstone disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194950"} {"pmid": "4194949", "title": "Children in isolation units.", "content": "Children in isolation units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194949"} {"pmid": "4194951", "title": "Hopeful regulations.", "content": "Hopeful regulations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194951"} {"pmid": "4194952", "title": "Injuries to knee ligaments and hypermobility.", "content": "Injuries to knee ligaments and hypermobility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194952"} {"pmid": "4194953", "title": "Initiation of protein synthesis.", "content": "Initiation of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194953"} {"pmid": "4194954", "title": "Housewives' hands.", "content": "Housewives' hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194954"} {"pmid": "4194955", "title": "Drift from science.", "content": "Drift from science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194955"} {"pmid": "4194956", "title": "Revolution in community welfare.", "content": "Revolution in community welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194956"} {"pmid": "4194957", "title": "A group home project.", "content": "A group home project.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194957"} {"pmid": "4194958", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194958"} {"pmid": "4194959", "title": "Intermittent complete heart-block.", "content": "Intermittent complete heart-block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194959"} {"pmid": "4194960", "title": "\"Renpenning\" syndrome.", "content": "\"Renpenning\" syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194960"} {"pmid": "4194961", "title": "Effect of anticonvulsant drugs on insecticide residues.", "content": "Effect of anticonvulsant drugs on insecticide residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194961"} {"pmid": "4194962", "title": "Phenobarbitone in posthepatitic unconjugated hyperbilirubinaemia.", "content": "Phenobarbitone in posthepatitic unconjugated hyperbilirubinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194962"} {"pmid": "4194963", "title": "Portable heparin injector.", "content": "Portable heparin injector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194963"} {"pmid": "4194964", "title": "Beta-hydroxyisovaleric aciduria and beta-methylcrotonylglycinuria: a new inborn error of metabolism.", "content": "Beta-hydroxyisovaleric aciduria and beta-methylcrotonylglycinuria: a new inborn error of metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194964"} {"pmid": "4194965", "title": "Screening for phenylketonuria.", "content": "Screening for phenylketonuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194965"} {"pmid": "4194966", "title": "An unusual case of rabies.", "content": "An unusual case of rabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194966"} {"pmid": "4194967", "title": "Immunoglobulins in schizophrenic patients.", "content": "Immunoglobulins in schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194967"} {"pmid": "4194968", "title": "Lithium distribution in the brains of two manic patients.", "content": "Lithium distribution in the brains of two manic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194968"} {"pmid": "4194969", "title": "Congenital chromosome abnormalities and leukaemia.", "content": "Congenital chromosome abnormalities and leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194969"} {"pmid": "4194970", "title": "Great corn mystery.", "content": "Great corn mystery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194970"} {"pmid": "4194971", "title": "The E.E.G. in herpes-simplex encephalitis.", "content": "The E.E.G. in herpes-simplex encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194971"} {"pmid": "4194972", "title": "Treatment of primary polycythaemia.", "content": "Treatment of primary polycythaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194972"} {"pmid": "4194973", "title": "Early effect of humanae vitae?", "content": "Early effect of humanae vitae?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194973"} {"pmid": "4194974", "title": "Studies from the hair.", "content": "Studies from the hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194974"} {"pmid": "4194976", "title": "Smoking and frusemide diuresis.", "content": "Smoking and frusemide diuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194976"} {"pmid": "4194975", "title": "Tetanus: new treatment and prophylaxis.", "content": "Tetanus: new treatment and prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194975"} {"pmid": "4194977", "title": "Corticotrophin-induced growth-hormone release.", "content": "Corticotrophin-induced growth-hormone release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194977"} {"pmid": "4194978", "title": "Is lyonisation total in man?", "content": "Is lyonisation total in man?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194978"} {"pmid": "4194979", "title": "Multiply resistant staphylococci.", "content": "Multiply resistant staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194979"} {"pmid": "4194980", "title": "Accelerated nucleic-acid synthesis in uraemic lymphocytes.", "content": "Accelerated nucleic-acid synthesis in uraemic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194980"} {"pmid": "4194981", "title": "Transformation of xerodermapigmentosum cells by SV40.", "content": "Transformation of xerodermapigmentosum cells by SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194981"} {"pmid": "4194982", "title": "G.M.C. retention fee.", "content": "G.M.C. retention fee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194982"} {"pmid": "4194983", "title": "Hypocholesterolaemia in anaemia.", "content": "Hypocholesterolaemia in anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194983"} {"pmid": "4194985", "title": "The diagnosis and treatment of children with learning and developmental problems. A community service for medical group practice.", "content": "The diagnosis and treatment of children with learning and developmental problems. A community service for medical group practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194985"} {"pmid": "4194989", "title": "Albumin metabolism and gastrointestinal protein loss in children with nephrotic syndrome.", "content": "Albumin metabolism and gastrointestinal protein loss in children with nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194989"} {"pmid": "4194990", "title": "Atypical changes in thyroid follicular cells secondary to radioiodine.", "content": "Atypical changes in thyroid follicular cells secondary to radioiodine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194990"} {"pmid": "4194992", "title": "Experimental atherosclerosis in normal and subdiabetic rabbits. I. Short-term studies.", "content": "Experimental atherosclerosis in normal and subdiabetic rabbits. I. Short-term studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194992"} {"pmid": "4194993", "title": "Angiotoxic activity of 4'fluoro-10-methyl-1,2-benzanthracene in the rat.", "content": "Angiotoxic activity of 4'fluoro-10-methyl-1,2-benzanthracene in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194993"} {"pmid": "4194994", "title": "Lysosomal site of crystalline deposits in cystinosis as shown by ferritin uptake.", "content": "Lysosomal site of crystalline deposits in cystinosis as shown by ferritin uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194994"} {"pmid": "4194995", "title": "Spectrum of aging changes in temporal arteries. Its significance, in interpretation of biopsy of temporal artery.", "content": "Spectrum of aging changes in temporal arteries. Its significance, in interpretation of biopsy of temporal artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194995"} {"pmid": "4194996", "title": "Naturally occurring human antibodies to pepsin-digested IgA.", "content": "Naturally occurring human antibodies to pepsin-digested IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194996"} {"pmid": "4194997", "title": "Benign prostatic hypertrophy and uraemia. A review of 315 cases.", "content": "Benign prostatic hypertrophy and uraemia. A review of 315 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194997"} {"pmid": "4194998", "title": "Recurrence of hyperthyroidism shortly after return of normal suppressibility by triiodothyronine.", "content": "Recurrence of hyperthyroidism shortly after return of normal suppressibility by triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4194998"} {"pmid": "4195001", "title": "Argyrophilic cells of the dog pancreas following different silver stains.", "content": "Argyrophilic cells of the dog pancreas following different silver stains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195001"} {"pmid": "4195003", "title": "Detection and characterization of DNA in mixed (IgG-IgM) cryoglobulins.", "content": "Detection and characterization of DNA in mixed (IgG-IgM) cryoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195003"} {"pmid": "4195004", "title": "The measurement of serum immunoglobulin E levels in healthy adults and children and in children with allergic asthma.", "content": "The measurement of serum immunoglobulin E levels in healthy adults and children and in children with allergic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195004"} {"pmid": "4195005", "title": "A study on the detection of human reagins with rat peritoneal mast cells.", "content": "A study on the detection of human reagins with rat peritoneal mast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195005"} {"pmid": "4195007", "title": "Serum lipoproteins of rats bearing transplanted Morris hepatoma 7777.", "content": "Serum lipoproteins of rats bearing transplanted Morris hepatoma 7777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195007"} {"pmid": "4195006", "title": "The immune responses and lymphoid tissues of neonatally thymectomized, X-irradiated mice.", "content": "The immune responses and lymphoid tissues of neonatally thymectomized, X-irradiated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195006"} {"pmid": "4195008", "title": "Hematologic findings in certain small cetaceans.", "content": "Hematologic findings in certain small cetaceans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195008"} {"pmid": "4195009", "title": "Naturally occurring cutaneous streptothricosis in a white-tailed deer (Odocoileus virginianus).", "content": "Naturally occurring cutaneous streptothricosis in a white-tailed deer (Odocoileus virginianus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195009"} {"pmid": "4195010", "title": "Type A enterotoxemia in captive wild goats.", "content": "Type A enterotoxemia in captive wild goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195010"} {"pmid": "4195012", "title": "The disposition of proteinpolysaccharide in the epiphysial plate cartilage of the young rabbit.", "content": "The disposition of proteinpolysaccharide in the epiphysial plate cartilage of the young rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195012"} {"pmid": "4195011", "title": "Subacute sclerosing panencephalitis-like syndrome in the adult baboon (Papio sp.).", "content": "Subacute sclerosing panencephalitis-like syndrome in the adult baboon (Papio sp.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195011"} {"pmid": "4195013", "title": "A multiple-choice audio-visual discrimination apparatus with quick interchange display and response panels.", "content": "A multiple-choice audio-visual discrimination apparatus with quick interchange display and response panels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195013"} {"pmid": "4195014", "title": "Medullary tractotomy. A surgical procedure providing relief from severe pain due to cancer of head and neck.", "content": "Medullary tractotomy. A surgical procedure providing relief from severe pain due to cancer of head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195014"} {"pmid": "4195015", "title": "A comparative study of blood fibrinolytic activity in normal women, pregnant women and women on oral contraceptives.", "content": "A comparative study of blood fibrinolytic activity in normal women, pregnant women and women on oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195015"} {"pmid": "4195037", "title": "Gastric cytology.", "content": "Gastric cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195037"} {"pmid": "4195038", "title": "Assessing immunization procedures.", "content": "Assessing immunization procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195038"} {"pmid": "4195041", "title": "Endocrine profile of a new progestational steroid. 4,6-dichloro-17 alpha-hydroxy-pregna-4,6-diene-3,20-dione, acetate (Ro 7-2133).", "content": "Endocrine profile of a new progestational steroid. 4,6-dichloro-17 alpha-hydroxy-pregna-4,6-diene-3,20-dione, acetate (Ro 7-2133).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195041"} {"pmid": "4195044", "title": "Successes and failures in the search for antibiotics.", "content": "Successes and failures in the search for antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195044"} {"pmid": "4195046", "title": "Recent progress in pharmacogenetics.", "content": "Recent progress in pharmacogenetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195046"} {"pmid": "4195047", "title": "In vivo histamine levels with hypoxia and compound 48-80.", "content": "In vivo histamine levels with hypoxia and compound 48-80.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195047"} {"pmid": "4195048", "title": "Demonstration of the fenesrated membrane (membrana fenestrata) in the human arterial wall by stained tissue segment.", "content": "Demonstration of the fenesrated membrane (membrana fenestrata) in the human arterial wall by stained tissue segment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195048"} {"pmid": "4195040", "title": "Rapid method for separation of blood cells.", "content": "Rapid method for separation of blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195040"} {"pmid": "4195049", "title": "The basis of differential staining of ascospores and vegetative cells of yeasts.", "content": "The basis of differential staining of ascospores and vegetative cells of yeasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195049"} {"pmid": "4195052", "title": "Studies on the immunogenicity of antigen-antibody precipitates. II. The suppressive effect of anti-carrier and anti-hapten antibodies on the immunogenicity of dinitrophenylated human gamma G globulin.", "content": "Studies on the immunogenicity of antigen-antibody precipitates. II. The suppressive effect of anti-carrier and anti-hapten antibodies on the immunogenicity of dinitrophenylated human gamma G globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195052"} {"pmid": "4195053", "title": "Cytochemical detection of cytochrome oxidase activity in bacteria.", "content": "Cytochemical detection of cytochrome oxidase activity in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195053"} {"pmid": "4195054", "title": "Morphology and entry of enveloped and deenveloped equine abortion (herpes) virus.", "content": "Morphology and entry of enveloped and deenveloped equine abortion (herpes) virus. Selective removal of the envelope of equine abortion (herpes) virus was accomplished by utilizing the nonionic detergent Nonidet P-40 followed by sonic treatment. The deenveloped particles differ significantly in size and buoyant density from the enveloped form. The cellular entry of purified enveloped and purified deenveloped virus was examined by electron microscopy during critical time periods. Both forms appeared to enter cells by a viropexis mechanism in which particles were engulfed by pseudopodia which either surround the virus and fuse with the cell membrane or to other pseudopodia, forming fusion vacuoles containing from one to numerous viral particles. This mode of entry was noted extensively at 5 min postinoculation. Deenveloped particles were apparently infectious only for hamsters, with a large inoculum being required. Contamination by enveloped forms was not noted after exhaustive search by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195054"} {"pmid": "4195055", "title": "Physical and biological properties of dengue-2 virus and associated antigens.", "content": "Physical and biological properties of dengue-2 virus and associated antigens. Dengue virus suspensions from mouse brain and cell culture were fractionated into three components by rate zonal centrifugation in sucrose gradients. Infectious virus sedimented in a single zone and possessed hemagglutinating (HA) and complement fixing (CF) activity. Electron micrographs showed the virion to be a spherical particle 48 to 50 nm in diameter with 7-nm spherical structures on its surface. Buoyant density in CsCl of virions from mouse brain was estimated at 1.22 g/cm(3) and from cell culture at 1.24 g/cm(3). During centrifugation of virions in CsCl, an additional HA component appeared with a buoyant density of 1.18 g/cm(3). It was shown in electron micrographs to consist of virion fragments. A noninfectious component with HA and CF activity sedimented in sucrose more slowly than intact virus, had a buoyant density of 1.23 g/cm(3) in CsCl, and appeared as \"doughnut\" forms measuring 13.8 to 14 nm in diameter. A third component, with CF activity and no HA activity, sedimented very little in sucrose gradients. Particles of the same size and shape as the spherical subunits on the surface of the virion were observed in electron micrographs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195055"} {"pmid": "4195058", "title": "Treatment of Gilbert's syndrome with phenobarbitone.", "content": "Treatment of Gilbert's syndrome with phenobarbitone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195058"} {"pmid": "4195060", "title": "Cancer prevention.", "content": "Cancer prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195060"} {"pmid": "4195062", "title": "Excess male false-positives among infants with phenylketonuria.", "content": "Excess male false-positives among infants with phenylketonuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195062"} {"pmid": "4195059", "title": "Parathyroid hormone and experimental osteosclerosis.", "content": "Parathyroid hormone and experimental osteosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195059"} {"pmid": "4195061", "title": "ABC of endocrinology. VI. The thyroid gland.", "content": "ABC of endocrinology. VI. The thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195061"} {"pmid": "4195063", "title": "Availability of candidates for consultant posts in chemical pathology.", "content": "Availability of candidates for consultant posts in chemical pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195063"} {"pmid": "4195065", "title": "Prevention of leucocyte-antibody formation.", "content": "Prevention of leucocyte-antibody formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195065"} {"pmid": "4195066", "title": "Reed-Sternberg-like cells in lymphocytic lymphoma and chronic lymphocytic leukaemia.", "content": "Reed-Sternberg-like cells in lymphocytic lymphoma and chronic lymphocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195066"} {"pmid": "4195067", "title": "Cataract surgery and intraocular implants.", "content": "Cataract surgery and intraocular implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195067"} {"pmid": "4195068", "title": "Heterotopic ciliated epithelium--müllerian origin?", "content": "Heterotopic ciliated epithelium--müllerian origin?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195068"} {"pmid": "4195069", "title": "Effect of corticotropin on plasma-growth-hormone.", "content": "Effect of corticotropin on plasma-growth-hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195069"} {"pmid": "4195070", "title": "Growth hormone in acute myocardial infarction.", "content": "Growth hormone in acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195070"} {"pmid": "4195071", "title": "Cytogenic analysis of cord-blood lymphocytes.", "content": "Cytogenic analysis of cord-blood lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195071"} {"pmid": "4195072", "title": "Relationship of diabetic retinopathy to blood-sugar.", "content": "Relationship of diabetic retinopathy to blood-sugar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195072"} {"pmid": "4195073", "title": "The electrocardiogram in males with the 47,XYY karyotype.", "content": "The electrocardiogram in males with the 47,XYY karyotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195073"} {"pmid": "4195074", "title": "Orange soles.", "content": "Orange soles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195074"} {"pmid": "4195075", "title": "Orange soles.", "content": "Orange soles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195075"} {"pmid": "4195076", "title": "Myalgia and bird-keeping.", "content": "Myalgia and bird-keeping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195076"} {"pmid": "4195077", "title": "House-dust, mites, and asthma.", "content": "House-dust, mites, and asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195077"} {"pmid": "4195078", "title": "Repair of the perineum.", "content": "Repair of the perineum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195078"} {"pmid": "4195079", "title": "Frederick Cecil Wray Capps, F.R.C.S.", "content": "Frederick Cecil Wray Capps, F.R.C.S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195079"} {"pmid": "4195080", "title": "Kidney function after transplantation.", "content": "Kidney function after transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195080"} {"pmid": "4195081", "title": "Opening of the cardia.", "content": "Opening of the cardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195081"} {"pmid": "4195083", "title": "Remarks on the nomenclature of cardiac arrhythmias.", "content": "Remarks on the nomenclature of cardiac arrhythmias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195083"} {"pmid": "4195084", "title": "The electrocardiogram in complicated acute myocardial infarction.", "content": "The electrocardiogram in complicated acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195084"} {"pmid": "4195085", "title": "Primary and secondary male characteristics: the hairiness and large penis stereotypes.", "content": "Primary and secondary male characteristics: the hairiness and large penis stereotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195085"} {"pmid": "4195091", "title": "Whipple's disease: newer concepts of therapy.", "content": "Whipple's disease: newer concepts of therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195091"} {"pmid": "4195088", "title": "Pulmonary hyaline membranes in adults receiving oxygen therapy.", "content": "Pulmonary hyaline membranes in adults receiving oxygen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195088"} {"pmid": "4195092", "title": "Morphology of transmissible gastroenteritis virus of pigs. A possible member of coronaviruses. Brief report.", "content": "Morphology of transmissible gastroenteritis virus of pigs. A possible member of coronaviruses. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195092"} {"pmid": "4195093", "title": "Characteristics of transducing group A streptococcal bacteriophages A 5 and A 25.", "content": "Characteristics of transducing group A streptococcal bacteriophages A 5 and A 25.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195093"} {"pmid": "4195094", "title": "Comparative immunofluorescent studies on measles, canine distemper, and rinderpest viruses. Immunofluorescence of measles, distemper, and rinderpest viruses.", "content": "Comparative immunofluorescent studies on measles, canine distemper, and rinderpest viruses. Immunofluorescence of measles, distemper, and rinderpest viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195094"} {"pmid": "4195096", "title": "Ultrastructural organization of spheroplasts induced in Mycobacterium sp. smegmatis by lysozyme or glycine.", "content": "Ultrastructural organization of spheroplasts induced in Mycobacterium sp. smegmatis by lysozyme or glycine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195096"} {"pmid": "4195098", "title": "Compensatory hormonogenic hyperactivity of thyroid homo- and autografts, as well as of regenerates in situ, in the thyroidectomized guinea pig--comparative chemical and radiobiological study.", "content": "Compensatory hormonogenic hyperactivity of thyroid homo- and autografts, as well as of regenerates in situ, in the thyroidectomized guinea pig--comparative chemical and radiobiological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195098"} {"pmid": "4195115", "title": "Effects of adhesive drapes on contamination of operation wounds.", "content": "Effects of adhesive drapes on contamination of operation wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195115"} {"pmid": "4195117", "title": "The fist as an external cardiac pacemaker.", "content": "The fist as an external cardiac pacemaker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195117"} {"pmid": "4195116", "title": "Intracranial-pressure changes following head injury.", "content": "Intracranial-pressure changes following head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195116"} {"pmid": "4195118", "title": "Comparison of fenfluramine and metformin in treatment of obesity.", "content": "Comparison of fenfluramine and metformin in treatment of obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195118"} {"pmid": "4195119", "title": "Discriminant function based on steroid abnormalities in patients with lung cancer.", "content": "Discriminant function based on steroid abnormalities in patients with lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195119"} {"pmid": "4195120", "title": "Sleep-walking in twins.", "content": "Sleep-walking in twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195120"} {"pmid": "4195121", "title": "Treatment of chronic hepatic encephalopathy.", "content": "Treatment of chronic hepatic encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195121"} {"pmid": "4195122", "title": "Dystrophia myotonica: identification of heterozygotes.", "content": "Dystrophia myotonica: identification of heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195122"} {"pmid": "4195123", "title": "A new line on age pigment?", "content": "A new line on age pigment?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195123"} {"pmid": "4195124", "title": "Selection of housemen.", "content": "Selection of housemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195124"} {"pmid": "4195125", "title": "Finding the typhoid carrier.", "content": "Finding the typhoid carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195125"} {"pmid": "4195126", "title": "A living wage.", "content": "A living wage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195126"} {"pmid": "4195127", "title": "Reserpine in Raynaud's phenomenon.", "content": "Reserpine in Raynaud's phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195127"} {"pmid": "4195128", "title": "One year's experience in a drug-dependence clinic.", "content": "One year's experience in a drug-dependence clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195128"} {"pmid": "4195130", "title": "Continuity of clinical training.", "content": "Continuity of clinical training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195130"} {"pmid": "4195129", "title": "Appointment of provisionally registered house-officers by computer match.", "content": "Appointment of provisionally registered house-officers by computer match.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195129"} {"pmid": "4195131", "title": "Population policy.", "content": "Population policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195131"} {"pmid": "4195133", "title": "Immunological approach to ageing.", "content": "Immunological approach to ageing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195133"} {"pmid": "4195132", "title": "Sterilisation of women.", "content": "Sterilisation of women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195132"} {"pmid": "4195134", "title": "Ketamine.", "content": "Ketamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195134"} {"pmid": "4195136", "title": "Variants of alpha-fetoprotein.", "content": "Variants of alpha-fetoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195136"} {"pmid": "4195135", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195135"} {"pmid": "4195137", "title": "Absence of alpha-1-fetoprotein antigen or antibody in maternal sera.", "content": "Absence of alpha-1-fetoprotein antigen or antibody in maternal sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195137"} {"pmid": "4195138", "title": "Alpha 1-fetoprotein in Spain.", "content": "Alpha 1-fetoprotein in Spain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195138"} {"pmid": "4195139", "title": "Screening blood donors for Au antigen.", "content": "Screening blood donors for Au antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195139"} {"pmid": "4195140", "title": "Australia antigen and hepatitis.", "content": "Australia antigen and hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195140"} {"pmid": "4195141", "title": "Phenobarbitone in intrahepatic biliary atresia.", "content": "Phenobarbitone in intrahepatic biliary atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195141"} {"pmid": "4195143", "title": "Free-radical damage in retrolental fibroplasia.", "content": "Free-radical damage in retrolental fibroplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195143"} {"pmid": "4195142", "title": "Battered babies.", "content": "Battered babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195142"} {"pmid": "4195144", "title": "Headache and the eye.", "content": "Headache and the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195144"} {"pmid": "4195145", "title": "Psychogeriatric assessment unit.", "content": "Psychogeriatric assessment unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195145"} {"pmid": "4195146", "title": "L.A.T.S. and Graves' disease.", "content": "L.A.T.S. and Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195146"} {"pmid": "4195147", "title": "Blood activity of 125-I-fibrinogen in venous thrombosis.", "content": "Blood activity of 125-I-fibrinogen in venous thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195147"} {"pmid": "4195148", "title": "Catecholamine metabolisn in sympathetic-tumour cells.", "content": "Catecholamine metabolisn in sympathetic-tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195148"} {"pmid": "4195149", "title": "L-dopa in progressive supranuclear palsy.", "content": "L-dopa in progressive supranuclear palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195149"} {"pmid": "4195150", "title": "Effects of withdrawing dopa in Parkinson's disease.", "content": "Effects of withdrawing dopa in Parkinson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195150"} {"pmid": "4195151", "title": "An epidemic of dysentery in Nicaragua.", "content": "An epidemic of dysentery in Nicaragua.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195151"} {"pmid": "4195152", "title": "Role of artificial lighting in decreasing the age of menarche.", "content": "Role of artificial lighting in decreasing the age of menarche.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195152"} {"pmid": "4195153", "title": "Growth hormone and diabetic angiopathy.", "content": "Growth hormone and diabetic angiopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195153"} {"pmid": "4195154", "title": "Dialysis circuit monitors.", "content": "Dialysis circuit monitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195154"} {"pmid": "4195155", "title": "Death attributed to kidney failure in communities with endemic urinary schistosomiasis.", "content": "Death attributed to kidney failure in communities with endemic urinary schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195155"} {"pmid": "4195156", "title": "Systemic nocardiosis treated with trimethoprim and sulphamethoxazole.", "content": "Systemic nocardiosis treated with trimethoprim and sulphamethoxazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195156"} {"pmid": "4195157", "title": "Detection of bacteriuria.", "content": "Detection of bacteriuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195157"} {"pmid": "4195158", "title": "Mycoplasma and the urogenital tract.", "content": "Mycoplasma and the urogenital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195158"} {"pmid": "4195159", "title": "Junior hospital staff in training.", "content": "Junior hospital staff in training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195159"} {"pmid": "4195160", "title": "Against vagotomy.", "content": "Against vagotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195160"} {"pmid": "4195161", "title": "Direction for health service research.", "content": "Direction for health service research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195161"} {"pmid": "4195162", "title": "Familial metaphyseal dysplasia?", "content": "Familial metaphyseal dysplasia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195162"} {"pmid": "4195163", "title": "Digestion in the newborn.", "content": "Digestion in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195163"} {"pmid": "4195164", "title": "ABO blood groups and Huntington's choera.", "content": "ABO blood groups and Huntington's choera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195164"} {"pmid": "4195167", "title": "Molar absorbance coefficient of rhodopsin.", "content": "Molar absorbance coefficient of rhodopsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195167"} {"pmid": "4195168", "title": "Clinical value of liver function appraisal by means of 131-I-rose bengal. II. Comparison of the results of 131-I-rose bengal test with other biochemical tests.", "content": "Clinical value of liver function appraisal by means of 131-I-rose bengal. II. Comparison of the results of 131-I-rose bengal test with other biochemical tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195168"} {"pmid": "4195170", "title": "Biochemical abnormalities associated with turkey syndrome '65.", "content": "Biochemical abnormalities associated with turkey syndrome '65.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195170"} {"pmid": "4195171", "title": "Studies on the thyroid activity in the mouse. 2. The effects of stress and other changes in corticotrophin secretion.", "content": "Studies on the thyroid activity in the mouse. 2. The effects of stress and other changes in corticotrophin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195171"} {"pmid": "4195172", "title": "Immunologic and electron microscopic studies in Goodpasture's syndrome.", "content": "Immunologic and electron microscopic studies in Goodpasture's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195172"} {"pmid": "4195173", "title": "Development and organization of periodontal membrane and physiologic tooth movement.", "content": "Development and organization of periodontal membrane and physiologic tooth movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195173"} {"pmid": "4195176", "title": "Interaction of antibiotics with deoxyribonucleic acid. I. Sensitivity of the complexes to nucleolytic enzymes.", "content": "Interaction of antibiotics with deoxyribonucleic acid. I. Sensitivity of the complexes to nucleolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195176"} {"pmid": "4195180", "title": "The spoken word: delivering a lecture, reading a paper, and giving a demonstration at congresses and meetings.", "content": "The spoken word: delivering a lecture, reading a paper, and giving a demonstration at congresses and meetings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195180"} {"pmid": "4195188", "title": "A unopette for eosinophil counts.", "content": "A unopette for eosinophil counts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195188"} {"pmid": "4195189", "title": "A staining technic for differentiating yeast cells from squamous epithelial nuclei on clinical smears.", "content": "A staining technic for differentiating yeast cells from squamous epithelial nuclei on clinical smears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195189"} {"pmid": "4195192", "title": "Iodine and thyroxine metabolism in anephric patients receiving chronic peritoneal dialysis.", "content": "Iodine and thyroxine metabolism in anephric patients receiving chronic peritoneal dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195192"} {"pmid": "4195193", "title": "Specific demonstration of the human hypophyseal cells which produce adrenocorticotropic hormone.", "content": "Specific demonstration of the human hypophyseal cells which produce adrenocorticotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195193"} {"pmid": "4195195", "title": "Thyroglobulin and thyroid acid protease activity in thyroid disease.", "content": "Thyroglobulin and thyroid acid protease activity in thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195195"} {"pmid": "4195196", "title": "Thyroid function in euthyroid Jamaicans.", "content": "Thyroid function in euthyroid Jamaicans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195196"} {"pmid": "4195194", "title": "Studies on tryptophan metabolism in male subjects treated with female sex hormones.", "content": "Studies on tryptophan metabolism in male subjects treated with female sex hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195194"} {"pmid": "4195198", "title": "9alpha-halogenated progestagens in the maintenance of pregnancy.", "content": "9alpha-halogenated progestagens in the maintenance of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195198"} {"pmid": "4195197", "title": "Response to synthetic thyrotropin-releasing hormone in man.", "content": "Response to synthetic thyrotropin-releasing hormone in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195197"} {"pmid": "4195200", "title": "The effect of dose level of intravaginal progestagen on sperm transport, fertilization and lambing in the cyclic Merino ewe.", "content": "The effect of dose level of intravaginal progestagen on sperm transport, fertilization and lambing in the cyclic Merino ewe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195200"} {"pmid": "4195201", "title": "Severe myositis during recovery from influenza.", "content": "Severe myositis during recovery from influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195201"} {"pmid": "4195199", "title": "An electron-microscope study of bacteria in two cases of Whipple's disease.", "content": "An electron-microscope study of bacteria in two cases of Whipple's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195199"} {"pmid": "4195202", "title": "Effect of age on calcium absorption.", "content": "Effect of age on calcium absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195202"} {"pmid": "4195203", "title": "Failure of corticosteroid therapy to correct the hypercalcaemia of malignant disease.", "content": "Failure of corticosteroid therapy to correct the hypercalcaemia of malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195203"} {"pmid": "4195204", "title": "Presentation of cadaveric kidneys for transplantation.", "content": "Presentation of cadaveric kidneys for transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195204"} {"pmid": "4195205", "title": "Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin.", "content": "Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195205"} {"pmid": "4195206", "title": "Serum-insulin or plasma-insulin?", "content": "Serum-insulin or plasma-insulin?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195206"} {"pmid": "4195207", "title": "Gastric secretion in a healthy man, 1949-69.", "content": "Gastric secretion in a healthy man, 1949-69.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195207"} {"pmid": "4195185", "title": "Immunological studies with papain and mexicain. II.", "content": "Immunological studies with papain and mexicain. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195185"} {"pmid": "4195208", "title": "Rapid correction of acidosis and dehydration of cholera with oral electrolyte and glucose solution.", "content": "Rapid correction of acidosis and dehydration of cholera with oral electrolyte and glucose solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195208"} {"pmid": "4195209", "title": "A waste-trap-sterilising method.", "content": "A waste-trap-sterilising method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195209"} {"pmid": "4195210", "title": "How many people?", "content": "How many people?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195210"} {"pmid": "4195211", "title": "Recurrent bacteriuria.", "content": "Recurrent bacteriuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195211"} {"pmid": "4195212", "title": "At what temperature should you keep a baby?", "content": "At what temperature should you keep a baby?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195212"} {"pmid": "4195213", "title": "Adding drugs to intravenous infusions.", "content": "Adding drugs to intravenous infusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195213"} {"pmid": "4195214", "title": "Left ventricular hypertrophy and ischaemic heart-disease.", "content": "Left ventricular hypertrophy and ischaemic heart-disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195214"} {"pmid": "4195215", "title": "Biological age of man.", "content": "Biological age of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195215"} {"pmid": "4195216", "title": "Corticosteroids and corticotrophins.", "content": "Corticosteroids and corticotrophins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195216"} {"pmid": "4195217", "title": "Prospects for social work in general practice.", "content": "Prospects for social work in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195217"} {"pmid": "4195218", "title": "Contamination of meat carcasses by antibiotic-resistant coliform bacteria.", "content": "Contamination of meat carcasses by antibiotic-resistant coliform bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195218"} {"pmid": "4195219", "title": "What about the colleges?", "content": "What about the colleges?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195219"} {"pmid": "4195220", "title": "Combined treatment of parkinsonism with L-dopa and amantadine.", "content": "Combined treatment of parkinsonism with L-dopa and amantadine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195220"} {"pmid": "4195221", "title": "Registrar General's supplement on abortion.", "content": "Registrar General's supplement on abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195221"} {"pmid": "4195222", "title": "Battered babies.", "content": "Battered babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195222"} {"pmid": "4195223", "title": "Tests for syphilis in children for adoption.", "content": "Tests for syphilis in children for adoption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195223"} {"pmid": "4195224", "title": "Ageing.", "content": "Ageing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195224"} {"pmid": "4195225", "title": "Animal sources of Escherichia coli in food.", "content": "Animal sources of Escherichia coli in food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195225"} {"pmid": "4195226", "title": "Treatment of chronic moniliasis with lymphocyte transfusions.", "content": "Treatment of chronic moniliasis with lymphocyte transfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195226"} {"pmid": "4195227", "title": "Ketamine and polyneuropathy.", "content": "Ketamine and polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195227"} {"pmid": "4195228", "title": "Precordial thumping.", "content": "Precordial thumping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195228"} {"pmid": "4195229", "title": "Gastrin secretion in the pancreas?", "content": "Gastrin secretion in the pancreas?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195229"} {"pmid": "4195230", "title": "Red-cell triosephosphate isomerase and chromosome 5.", "content": "Red-cell triosephosphate isomerase and chromosome 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195230"} {"pmid": "4195231", "title": "Diabetes and migraine.", "content": "Diabetes and migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195231"} {"pmid": "4195232", "title": "Painful deep-vein syndrome.", "content": "Painful deep-vein syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195232"} {"pmid": "4195233", "title": "Hyperparathyroidism in chronic renal failure.", "content": "Hyperparathyroidism in chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195233"} {"pmid": "4195234", "title": "Role of artificial lighting in decreasing the age of menarche.", "content": "Role of artificial lighting in decreasing the age of menarche.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195234"} {"pmid": "4195235", "title": "Aetiology of Crohn's disease.", "content": "Aetiology of Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195235"} {"pmid": "4195236", "title": "B.C.G. treatment in Crohn's disease.", "content": "B.C.G. treatment in Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195236"} {"pmid": "4195237", "title": "Control of tuberculosis.", "content": "Control of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195237"} {"pmid": "4195238", "title": "Syndrome of the sea-blue histiocyte.", "content": "Syndrome of the sea-blue histiocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195238"} {"pmid": "4195239", "title": "Infectious hepatitis and Down's syndrome.", "content": "Infectious hepatitis and Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195239"} {"pmid": "4195240", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195240"} {"pmid": "4195241", "title": "Control of lymphocyte level in the blood.", "content": "Control of lymphocyte level in the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195241"} {"pmid": "4195242", "title": "Effect of psychotomimetic agents on sex ratio?", "content": "Effect of psychotomimetic agents on sex ratio?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195242"} {"pmid": "4195243", "title": "Regular haemodialysis and renal transplantation.", "content": "Regular haemodialysis and renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195243"} {"pmid": "4195245", "title": "Occult blood.", "content": "Occult blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195245"} {"pmid": "4195244", "title": "Platelet adhesiveness in Hageman trait.", "content": "Platelet adhesiveness in Hageman trait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195244"} {"pmid": "4195246", "title": "Milk-bottle problem.", "content": "Milk-bottle problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195246"} {"pmid": "4195247", "title": "Design of skin flaps.", "content": "Design of skin flaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195247"} {"pmid": "4195248", "title": "Severe hypoglycaemia after glibenclamide.", "content": "Severe hypoglycaemia after glibenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195248"} {"pmid": "4195249", "title": "Robert Francis Jack Henry, M.B. Dubl., F.R.C.S.I.", "content": "Robert Francis Jack Henry, M.B. Dubl., F.R.C.S.I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195249"} {"pmid": "4195250", "title": "Automatic hand viewers and cassette play-back units.", "content": "Automatic hand viewers and cassette play-back units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195250"} {"pmid": "4195251", "title": "Learning carrels in a clinical course.", "content": "Learning carrels in a clinical course.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195251"} {"pmid": "4195252", "title": "Individualized instruction for the college curriculum.", "content": "Individualized instruction for the college curriculum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195252"} {"pmid": "4195254", "title": "Diffuse cutaneous leishmaniasis in Ethiopia. 3. Immunological studies. IV. Pathogenesis of diffuse cutaneous leishmaniasis.", "content": "Diffuse cutaneous leishmaniasis in Ethiopia. 3. Immunological studies. IV. Pathogenesis of diffuse cutaneous leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195254"} {"pmid": "4195270", "title": "Remarks to the haemogram of the pheasants.", "content": "Remarks to the haemogram of the pheasants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195270"} {"pmid": "4195298", "title": "Effect of macrophage engulfment and temperature on the transformation process of Leishmania donovani.", "content": "Effect of macrophage engulfment and temperature on the transformation process of Leishmania donovani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195298"} {"pmid": "4195299", "title": "The fine structure of human somatic chromosomes studied by scanning electron microscopy and the replica method.", "content": "The fine structure of human somatic chromosomes studied by scanning electron microscopy and the replica method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195299"} {"pmid": "4195300", "title": "Inactivation of \"Arvin\" by plasma proteins.", "content": "Inactivation of \"Arvin\" by plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195300"} {"pmid": "4195302", "title": "Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. I. Positive staining.", "content": "Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. I. Positive staining.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195302"} {"pmid": "4195304", "title": "A contribution to staining of Treponema pallidum in tissue. II. Concentration of silver nitrate solution suitable for staining of Treponema pallidum in tissue.", "content": "A contribution to staining of Treponema pallidum in tissue. II. Concentration of silver nitrate solution suitable for staining of Treponema pallidum in tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195304"} {"pmid": "4195305", "title": "Fluorescence in skin cancer showing verruca senilis in appearance.", "content": "Fluorescence in skin cancer showing verruca senilis in appearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195305"} {"pmid": "4195303", "title": "A contribution to staining of Treponema pallidum in tissue. I. Staining of Treponema pallidum in tissue using silver staining solution with surface-active agents.", "content": "A contribution to staining of Treponema pallidum in tissue. I. Staining of Treponema pallidum in tissue using silver staining solution with surface-active agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195303"} {"pmid": "4195306", "title": "A contribution to staining of Treponema pallidum in tissue. 3. An evaluation of surface-active agents for staining of Treponema pallidum in tissue.", "content": "A contribution to staining of Treponema pallidum in tissue. 3. An evaluation of surface-active agents for staining of Treponema pallidum in tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195306"} {"pmid": "4195307", "title": "Application of fluorescent dyes to dermatological investigation. V. Fluorescent microscopial study of squamous cell carcinoma.", "content": "Application of fluorescent dyes to dermatological investigation. V. Fluorescent microscopial study of squamous cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195307"} {"pmid": "4195308", "title": "A contribution to staining of Treponema pallidum in tissue. IV. Staining of Treponema pallidum in tissue of syphilid in test-rabbit and man.", "content": "A contribution to staining of Treponema pallidum in tissue. IV. Staining of Treponema pallidum in tissue of syphilid in test-rabbit and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195308"} {"pmid": "4195309", "title": "Application of fluorescent dyes to dermatological investigation. VI. Fluorescent microscopical study of precancerous state and basal cell carcinoma.", "content": "Application of fluorescent dyes to dermatological investigation. VI. Fluorescent microscopical study of precancerous state and basal cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195309"} {"pmid": "4195310", "title": "Symbolic interaction: analysis of listening.", "content": "Symbolic interaction: analysis of listening.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195310"} {"pmid": "4195315", "title": "Comparison of video-tape and face-to-face interviewing.", "content": "Comparison of video-tape and face-to-face interviewing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195315"} {"pmid": "4195318", "title": "Computerized data analysis of hemodialyzers by a standard protocol shows true effective membrane area.", "content": "Computerized data analysis of hemodialyzers by a standard protocol shows true effective membrane area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195318"} {"pmid": "4195319", "title": "Multiple antibody response following busulfan therapy.", "content": "Multiple antibody response following busulfan therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195319"} {"pmid": "4195325", "title": "Desmosomes and hemidesmosomes in the flagellate Crithidia fasciculata.", "content": "Desmosomes and hemidesmosomes in the flagellate Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195325"} {"pmid": "4195326", "title": "Ultrastructural studies of spontaneous spermiation in the guinea pig.", "content": "Ultrastructural studies of spontaneous spermiation in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195326"} {"pmid": "4195327", "title": "Fine structure of pars neuro-intermedia of the loach, Misgurnus fossilis L.", "content": "Fine structure of pars neuro-intermedia of the loach, Misgurnus fossilis L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195327"} {"pmid": "4195328", "title": "Fine structure of the vessels of the hypophysial portal system of the white-crowned sparrow, Zonotrichia leucophrys gambelii.", "content": "Fine structure of the vessels of the hypophysial portal system of the white-crowned sparrow, Zonotrichia leucophrys gambelii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195328"} {"pmid": "4195330", "title": "I-125 labelled thyroid hormones in cultured mammalian nerve tissue.", "content": "I-125 labelled thyroid hormones in cultured mammalian nerve tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195330"} {"pmid": "4195334", "title": "On surgical treatment of prostatic hyperplasia.", "content": "On surgical treatment of prostatic hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195334"} {"pmid": "4195335", "title": "Malaria: host-defense mechanisms and complications.", "content": "Malaria: host-defense mechanisms and complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195335"} {"pmid": "4195336", "title": "Methodological observations on the histochemical demonstration of glycogen phosphorylase activity.", "content": "Methodological observations on the histochemical demonstration of glycogen phosphorylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195336"} {"pmid": "4195337", "title": "The bile canaliculi in experimental liver disorders. A cytochemical study in guinea pigs.", "content": "The bile canaliculi in experimental liver disorders. A cytochemical study in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195337"} {"pmid": "4195338", "title": "Effect of anaesthesia on the behaviour of exogenous 5HT in area postrema of rat and mouse brain studies by fluorescence microscopy.", "content": "Effect of anaesthesia on the behaviour of exogenous 5HT in area postrema of rat and mouse brain studies by fluorescence microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195338"} {"pmid": "4195340", "title": "Sarcoidosis with atrophic lesions and ulcers and the presence in some sarcoid granulomata of orceinophil fibres.", "content": "Sarcoidosis with atrophic lesions and ulcers and the presence in some sarcoid granulomata of orceinophil fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195340"} {"pmid": "4195341", "title": "An unusual variant of lupus erythematosus or lichen planus.", "content": "An unusual variant of lupus erythematosus or lichen planus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195341"} {"pmid": "4195342", "title": "The cell surface coat of normal keratinocytes and of acantholytic keratinocytes in pemphigus. An electron microscopic study.", "content": "The cell surface coat of normal keratinocytes and of acantholytic keratinocytes in pemphigus. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195342"} {"pmid": "4195343", "title": "Symbolism in the treatment of schizophrenia.", "content": "Symbolism in the treatment of schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195343"} {"pmid": "4195344", "title": "Human fascioliasis in Shropshire.", "content": "Human fascioliasis in Shropshire. Five patients with fascioliasis presented with malaise, pruritus, and pain in the right hypochondrium. Eosinophilia, increase in serum gamma globulin, and pyrexia were other features. Four patients treated with oral bithionol recovered completely and it is suggested that this is an effective form of therapy. The double diffusion precipitin test, being speedy and simple, was used as a screening procedure for diagnosis. The source of infection was wild watercress growing in a farm ditch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195344"} {"pmid": "4195345", "title": "Propranolol and serum calcium in thyrotoxicosis.", "content": "Propranolol and serum calcium in thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195345"} {"pmid": "4195346", "title": "A controlled trial of three regimens of self-administered and supervised chemotherapy for pulmonary tuberculosis. A. General report.", "content": "A controlled trial of three regimens of self-administered and supervised chemotherapy for pulmonary tuberculosis. A. General report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195346"} {"pmid": "4195358", "title": "Emetine myopathy.", "content": "Emetine myopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195358"} {"pmid": "4195360", "title": "Investigation of the symbolic self using the concentric circles method and animal metaphor.", "content": "Investigation of the symbolic self using the concentric circles method and animal metaphor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195360"} {"pmid": "4195361", "title": "Authoritarianism among white and black deaf adolescents: two measures compared.", "content": "Authoritarianism among white and black deaf adolescents: two measures compared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195361"} {"pmid": "4195359", "title": "Antineuronal antibodies in patients having myasthenia gravis.", "content": "Antineuronal antibodies in patients having myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195359"} {"pmid": "4195372", "title": "Biosynthesis of gramicidin S.", "content": "Biosynthesis of gramicidin S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195372"} {"pmid": "4195373", "title": "Electron microscopy of enzymes.", "content": "Electron microscopy of enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195373"} {"pmid": "4195376", "title": "The cell population in pancreatic islets of Amphisbaenidae--a light and electron microscopic study.", "content": "The cell population in pancreatic islets of Amphisbaenidae--a light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195376"} {"pmid": "4195374", "title": "Clinicopathologic study of 53 cases of Brenner's tumors of the ovary.", "content": "Clinicopathologic study of 53 cases of Brenner's tumors of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195374"} {"pmid": "4195375", "title": "Morphology of alveolar lining layer.", "content": "Morphology of alveolar lining layer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195375"} {"pmid": "4195378", "title": "Fine structural study of rat molar cementum.", "content": "Fine structural study of rat molar cementum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195378"} {"pmid": "4195377", "title": "A histochemical and fine structural study of early extracellular connective tissue in the chick embryo.", "content": "A histochemical and fine structural study of early extracellular connective tissue in the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195377"} {"pmid": "4195379", "title": "Brunner's glands of the echidna.", "content": "Brunner's glands of the echidna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195379"} {"pmid": "4195381", "title": "Advances in asthma. Hypersensitivity mechanisms.", "content": "Advances in asthma. Hypersensitivity mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195381"} {"pmid": "4195385", "title": "Immunospecificity of fluorescein-conjugated anti-human beta 1C-globulin method for detection of cell-bound antibody.", "content": "Immunospecificity of fluorescein-conjugated anti-human beta 1C-globulin method for detection of cell-bound antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195385"} {"pmid": "4195386", "title": "Specific inhibition of acid phosphatase-3 in pollen of maize by the diazonium salt fast garnet GBC.", "content": "Specific inhibition of acid phosphatase-3 in pollen of maize by the diazonium salt fast garnet GBC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195386"} {"pmid": "4195387", "title": "Histochemical azo coupling reactions of the pigments of obstructive icterus and of hematoidin. I. Diazonium salts used.", "content": "Histochemical azo coupling reactions of the pigments of obstructive icterus and of hematoidin. I. Diazonium salts used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195387"} {"pmid": "4195388", "title": "Exogenous cytochrome c as an ultrastructural tracer.", "content": "Exogenous cytochrome c as an ultrastructural tracer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195388"} {"pmid": "4195389", "title": "Fluorescent nuclear staining with europium thenolytrifluoroacetonate.", "content": "Fluorescent nuclear staining with europium thenolytrifluoroacetonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195389"} {"pmid": "4195390", "title": "An introduction to electrocardiography by an automatic audio-visual technique.", "content": "An introduction to electrocardiography by an automatic audio-visual technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195390"} {"pmid": "4195394", "title": "Measles (rubeola) in previously immunized children.", "content": "Measles (rubeola) in previously immunized children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195394"} {"pmid": "4195395", "title": "Am(1), the first genetic marker of human immunoglobulin A.", "content": "Am(1), the first genetic marker of human immunoglobulin A. The genetic markers of human immunoglobulins have significantly contributed to the understanding of the molecular biology of antibody synthesis. Like the Gm markers of IgG, the first genetic marker of serum IgA, a major immunoglubulin of exocrine secretions, has now been defined and termed Am(1). It is inherited as a Mendelian dominant trait and is independent of the Gm and Inv allotypes. Am(1) is localized in the alpha-chains of the gammaA(2) subclass and is independent of the serum gammaA(2) levels. Its polymorphism makes it suitable for studies in population genetics and the molecular biology of IgA globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195395"} {"pmid": "4195396", "title": "Properties of halves of immunoglobulin light chains.", "content": "Properties of halves of immunoglobulin light chains. Light polypeptide chains from both normal human gammaG immunoglobulin and Bence-Jones proteins can be cleaved into halves by limited proteolysis with trypsin, pepsin, or papain. The fragments were obtained in yields of up to 22 per cent, had molecular weights of 10,000 to 11,000, and were shown by amino acid analysis and antigenic analysis to correspond to variable or constant regions of light chains. Starch gel electrophoresis in urea suggested that each half consisted of a single polypeptide chain. A fragment from the urine of a myeloma patient corresponded almost exactly to the constant half of a gamma-chain and had a compact shape (Stokes radius of 16 A; frictional ratio of 1.1). Similar Stokes radii were estimated both on fragments from normal urine and fragments produced by proteolysis of normal light chains. The results are consistent with the view that most urinary fragments have a catabolic origin and suggest that there is a small stretch of polypeptide chain between the compact V and C regions of light chains which is particularly susceptible to proteolysis. This lends support to the hypothesis that immunoglobulin chains consist of globular domains connected by more extended stretches of polypeptide chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195396"} {"pmid": "4195398", "title": "Allergic protein-losing gastroenteropathy: report of an unusual case.", "content": "Allergic protein-losing gastroenteropathy: report of an unusual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195398"} {"pmid": "4195401", "title": "Intracellular staining of physiologically identified interneurones in the cat spinal cord.", "content": "Intracellular staining of physiologically identified interneurones in the cat spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195401"} {"pmid": "4195402", "title": "Suppurative parotitis in children.", "content": "Suppurative parotitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195402"} {"pmid": "4195403", "title": "Sudden unexpected death (SUD).", "content": "Sudden unexpected death (SUD).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195403"} {"pmid": "4195404", "title": "The effects of d-tubocurarine on spontaneous postganglionic sympathetic activity and histamine release.", "content": "The effects of d-tubocurarine on spontaneous postganglionic sympathetic activity and histamine release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195404"} {"pmid": "4195409", "title": "Dual staining of some sulfated mucopolysaccharides with alcian blue (pH 1.0) and ruthenium red (pH 2.5).", "content": "Dual staining of some sulfated mucopolysaccharides with alcian blue (pH 1.0) and ruthenium red (pH 2.5).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195409"} {"pmid": "4195410", "title": "A simplified benzoylation-diazonium coupling sequence for demonstrating conjugated proteins.", "content": "A simplified benzoylation-diazonium coupling sequence for demonstrating conjugated proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195410"} {"pmid": "4195420", "title": "Effects of low concentrations of thyroid stimulating hormone: pharmacological experiments in vitro.", "content": "Effects of low concentrations of thyroid stimulating hormone: pharmacological experiments in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195420"} {"pmid": "4195421", "title": "Treatment of toxic nodular and diffuse goitre with radioactive iodine. Late results and use of carbimazole.", "content": "Treatment of toxic nodular and diffuse goitre with radioactive iodine. Late results and use of carbimazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195421"} {"pmid": "4195422", "title": "Effects of continuous daily administration of 0.3 mg of norehtindrone on the plasma levels of progesterone and on the urinary excretion of pregnanediol and total oestrogens.", "content": "Effects of continuous daily administration of 0.3 mg of norehtindrone on the plasma levels of progesterone and on the urinary excretion of pregnanediol and total oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195422"} {"pmid": "4195423", "title": "Demonstration of splenic metallophilic cells in bacterial infectious disease.", "content": "Demonstration of splenic metallophilic cells in bacterial infectious disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195423"} {"pmid": "4195425", "title": "Selective injury of mitochondria with Janus green B and ruby laser light--enzyme morphological and ultrastructural study.", "content": "Selective injury of mitochondria with Janus green B and ruby laser light--enzyme morphological and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195425"} {"pmid": "4195424", "title": "Experimental amyloidosis induced by immune complex or heat denatur ed DNA. I. An electron microscopic observation.", "content": "Experimental amyloidosis induced by immune complex or heat denatur ed DNA. I. An electron microscopic observation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195424"} {"pmid": "4195426", "title": "Interaction, a teaching tool in chemistry education.", "content": "Interaction, a teaching tool in chemistry education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195426"} {"pmid": "4195432", "title": "Simplified method for estimation of serum and plasma viscosity in multiple myeloma and related disorders.", "content": "Simplified method for estimation of serum and plasma viscosity in multiple myeloma and related disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195432"} {"pmid": "4195439", "title": "Albumin and IgG turnover studies in patients with cirrhosis.", "content": "Albumin and IgG turnover studies in patients with cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195439"} {"pmid": "4195440", "title": "Immunoglobulin M (IgM) turnover in hepatitis.", "content": "Immunoglobulin M (IgM) turnover in hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195440"} {"pmid": "4195441", "title": "The effects of azathioprin in patients with cirrhosis of the liver.", "content": "The effects of azathioprin in patients with cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195441"} {"pmid": "4195442", "title": "Alcoholic hepatitis in the spectrum of ethanol-induced liver injury.", "content": "Alcoholic hepatitis in the spectrum of ethanol-induced liver injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195442"} {"pmid": "4195447", "title": "Modeling and transfer of composed bone autograft in tubed flap--in experiment.", "content": "Modeling and transfer of composed bone autograft in tubed flap--in experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195447"} {"pmid": "4195448", "title": "Neurofibromatosis of the head.", "content": "Neurofibromatosis of the head.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195448"} {"pmid": "4195449", "title": "New method of plastic operation of pharyngoesophageal tract in case of extensive laryngectomy because of cancer.", "content": "New method of plastic operation of pharyngoesophageal tract in case of extensive laryngectomy because of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195449"} {"pmid": "4195451", "title": "Contribution to the research of malformations on the hands.", "content": "Contribution to the research of malformations on the hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195451"} {"pmid": "4195450", "title": "The task of sex and age in formation of Dupuytren's contracture.", "content": "The task of sex and age in formation of Dupuytren's contracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195450"} {"pmid": "4195452", "title": "Results of tubed pedicle flap plasty in large and complicated eyelid defects.", "content": "Results of tubed pedicle flap plasty in large and complicated eyelid defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195452"} {"pmid": "4195453", "title": "Transplantation of homologous cartilage sterilized in formalin vapours. (Preliminary report).", "content": "Transplantation of homologous cartilage sterilized in formalin vapours. (Preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195453"} {"pmid": "4195454", "title": "In memoriam Frantisek Burian, the founder of the Czechoslovak plastic and reconstructive surgery.", "content": "In memoriam Frantisek Burian, the founder of the Czechoslovak plastic and reconstructive surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195454"} {"pmid": "4195455", "title": "Histamine release inhibition in anti-inflammatory mechanism.", "content": "Histamine release inhibition in anti-inflammatory mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195455"} {"pmid": "4195456", "title": "Binding of photosensitizing dyes with some biopolymers.", "content": "Binding of photosensitizing dyes with some biopolymers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195456"} {"pmid": "4195458", "title": "Ultrastructure and distribution of neuronal and glial elements on the motoneuron surface in the lumbosacral spinal cord of the adult cat.", "content": "Ultrastructure and distribution of neuronal and glial elements on the motoneuron surface in the lumbosacral spinal cord of the adult cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195458"} {"pmid": "4195457", "title": "Diagnosis of beta thalassaemia in the newborn by means of haemoglobin synthesis.", "content": "Diagnosis of beta thalassaemia in the newborn by means of haemoglobin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195457"} {"pmid": "4195459", "title": "Fetoprotein and albumin levels in the blood serum of developing neonatal pigs.", "content": "Fetoprotein and albumin levels in the blood serum of developing neonatal pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195459"} {"pmid": "4195460", "title": "Comparative circular dichroism studies of individual eel and human antibodies.", "content": "Comparative circular dichroism studies of individual eel and human antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195460"} {"pmid": "4195461", "title": "Immunoglobulin formation and function in different tissues.", "content": "Immunoglobulin formation and function in different tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195461"} {"pmid": "4195465", "title": "Special aids for the 1971 National Children's Dental Health Week. Bureau of Dental Health Education.", "content": "Special aids for the 1971 National Children's Dental Health Week. Bureau of Dental Health Education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195465"} {"pmid": "4195466", "title": "Perfusion of the superior cervical ganglion of the cat with anti-permeable substance.", "content": "Perfusion of the superior cervical ganglion of the cat with anti-permeable substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195466"} {"pmid": "4195467", "title": "The assessment of thyroid function by in-vitro techniques. A comparison of commercial kits.", "content": "The assessment of thyroid function by in-vitro techniques. A comparison of commercial kits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195467"} {"pmid": "4195468", "title": "The bile canaliculi in cytological aspiration biopsies from patients with liver disorders.", "content": "The bile canaliculi in cytological aspiration biopsies from patients with liver disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195468"} {"pmid": "4195462", "title": "Rheumatoid-factor-like substance and antistreptolysin O antibody in leprosy serum. Significance in erythema nodosum leprosum.", "content": "Rheumatoid-factor-like substance and antistreptolysin O antibody in leprosy serum. Significance in erythema nodosum leprosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195462"} {"pmid": "4195474", "title": "Method for permanent in situ display of retinal nerve fiber layer anatomy.", "content": "Method for permanent in situ display of retinal nerve fiber layer anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195474"} {"pmid": "4195463", "title": "Leprosy. II. IgA and IgM immunoproteins in leprosy sera.", "content": "Leprosy. II. IgA and IgM immunoproteins in leprosy sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195463"} {"pmid": "4195475", "title": "Acute schistosomiasis Mansoni in 10 boys. An outbreak in Caguas, Puerto Rico.", "content": "Acute schistosomiasis Mansoni in 10 boys. An outbreak in Caguas, Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195475"} {"pmid": "4195476", "title": "Thyrotoxicosis presenting as choreoathetosis.", "content": "Thyrotoxicosis presenting as choreoathetosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195476"} {"pmid": "4195464", "title": "Leprosy. 3. A comparison of IgA and IgM immunoproteins of patients with pulmonary tuberculosis and leprosy.", "content": "Leprosy. 3. A comparison of IgA and IgM immunoproteins of patients with pulmonary tuberculosis and leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195464"} {"pmid": "4195477", "title": "Cytochemical electron microscopic localization o esterase activity in Lactobacillus casei.", "content": "Cytochemical electron microscopic localization o esterase activity in Lactobacillus casei. Enzymes capable of hydrolyzing thiolacetic acid in two strains of Lactobacillus casei were localized by the formation of electron-opaque PbS deposits in vivo in the presence of Pb(NO(3))(2). By electron microscopy, the deposition of PbS appeared primarily at the plasma membrane and at the outer surface of the cell wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195477"} {"pmid": "4195478", "title": "Nuclear distribution in the mycelium of Claviceps and the problem of strain selection.", "content": "Nuclear distribution in the mycelium of Claviceps and the problem of strain selection. Cytological studies of the developing mycelium of Claviceps suggest that genetic uniformity may be obtained in strains derived from single spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195478"} {"pmid": "4195473", "title": "Infiltrative diseases of the small bowel and malabsorption.", "content": "Infiltrative diseases of the small bowel and malabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195473"} {"pmid": "4195480", "title": "Application of freeze-etching method to the study of reovirus-infected LLC-MK2 cells.", "content": "Application of freeze-etching method to the study of reovirus-infected LLC-MK2 cells. A continuous cell line of rhesus monkey kidney cells, LLC-MK(2), was infected with reovirus type 1 (Lang). The cells were freeze-etched as a method for observing the structural details of the reovirus-induced cytoplasmic inclusion. Information on maturation may be obtained by preparing infected cells for electron microscopy by freeze-etching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195480"} {"pmid": "4195479", "title": "Volutin granules in Zoogloea ramigera.", "content": "Volutin granules in Zoogloea ramigera. Zoogloea ramigera, a gram-negative bacterium found in activated sludge, formed volutin granules when excess orthophosphate was added to a phosphate-starved culture. These volutin granules were stainable by hydrogen sulfide after lead acetate treatment and extractable by N-perchloric acid but were not adsorbed by activated charcoal. They appeared to consist of inorganic polyphosphate. Optimum granule formation in the arginine broth required 10 g of glucose, 3 mg of phosphate, and 1 to 20 mg of magnesium per liter of medium. At an Mg(2+) concentration of 1 mg/liter, very large granules appeared which often appeared to fill the cell. An excess of glucose, orthophosphate, or magnesium reduced granule formation. In the absence of sulfate, moderate granulation occurred in arginine broth before the addition of excess orthophosphate; granulation did not increase after the addition of phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195479"} {"pmid": "4195481", "title": "Lanthanum staining of Langerhans' cell. Communication of Langerhans' cell granules with extracellular space.", "content": "Lanthanum staining of Langerhans' cell. Communication of Langerhans' cell granules with extracellular space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195481"} {"pmid": "4195482", "title": "Formalin pigment in skin.", "content": "Formalin pigment in skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195482"} {"pmid": "4195483", "title": "Macromolecular assemblies of lipid in bile.", "content": "Macromolecular assemblies of lipid in bile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195483"} {"pmid": "4195484", "title": "Immunofluorescent localization of mammary tumor virus antigens in mammary tumor cells in culture.", "content": "Immunofluorescent localization of mammary tumor virus antigens in mammary tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195484"} {"pmid": "4195486", "title": "Localization of two species specific antigenic determinants on the peptide chains of calf skin collagen.", "content": "Localization of two species specific antigenic determinants on the peptide chains of calf skin collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195486"} {"pmid": "4195488", "title": "Role of erythrocyte destruction products in the mechanism of erythropoiesis autoregulation.", "content": "Role of erythrocyte destruction products in the mechanism of erythropoiesis autoregulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195488"} {"pmid": "4195495", "title": "Antigenicity of polypeptides (poly alpha amino acids): calcium-dependent and independent antibodies.", "content": "Antigenicity of polypeptides (poly alpha amino acids): calcium-dependent and independent antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195495"} {"pmid": "4195497", "title": "Independence of allotypic determinants and antibody specificity.", "content": "Independence of allotypic determinants and antibody specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195497"} {"pmid": "4195496", "title": "Delayed hypersensitivity to insulin and its component polypeptide chains.", "content": "Delayed hypersensitivity to insulin and its component polypeptide chains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195496"} {"pmid": "4195498", "title": "Quantitation of canine immunoglobulins.", "content": "Quantitation of canine immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195498"} {"pmid": "4195500", "title": "Structural studies of immunoglobulin E. II. Amino terminal sequence of the heavy chain.", "content": "Structural studies of immunoglobulin E. II. Amino terminal sequence of the heavy chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195500"} {"pmid": "4195499", "title": "The evolution of the immune response. VII. Antibody to human \"O\" cells and properties of the immunoglobulin in lamprey.", "content": "The evolution of the immune response. VII. Antibody to human \"O\" cells and properties of the immunoglobulin in lamprey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195499"} {"pmid": "4195501", "title": "Measurement of IgA levels in human cord serum by a new radioimmunoassay.", "content": "Measurement of IgA levels in human cord serum by a new radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195501"} {"pmid": "4195504", "title": "Senate wins clean car race.", "content": "Senate wins clean car race.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195504"} {"pmid": "4195505", "title": "Iodination and the biological activity of gastrin.", "content": "Iodination and the biological activity of gastrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195505"} {"pmid": "4195506", "title": "Anthropological significance of gamma globulin (Gm and Inv) antigens in Bougainville Island, Melanesia.", "content": "Anthropological significance of gamma globulin (Gm and Inv) antigens in Bougainville Island, Melanesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195506"} {"pmid": "4195507", "title": "Mixed lymphocyte cultures and HL-A identity in unrelated subjects.", "content": "Mixed lymphocyte cultures and HL-A identity in unrelated subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195507"} {"pmid": "4195508", "title": "In vitro sensitization of mouse peritoneal mast cells with reaginic antibody.", "content": "In vitro sensitization of mouse peritoneal mast cells with reaginic antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195508"} {"pmid": "4195512", "title": "Conservative management of genial tubercle fractures.", "content": "Conservative management of genial tubercle fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195512"} {"pmid": "4195513", "title": "A phantom head for teaching dental radiography.", "content": "A phantom head for teaching dental radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195513"} {"pmid": "4195514", "title": "Bubble chamber pictures as a means of demonstrating radiation distribution in biological systems.", "content": "Bubble chamber pictures as a means of demonstrating radiation distribution in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195514"} {"pmid": "4195517", "title": "Silver staining of micro- and oligodendroglia by means of physical development.", "content": "Silver staining of micro- and oligodendroglia by means of physical development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195517"} {"pmid": "4195518", "title": "Silver staining of fibrous neuroglia by means of physical development.", "content": "Silver staining of fibrous neuroglia by means of physical development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195518"} {"pmid": "4195519", "title": "Morphological studies of the neural spread of herpes simplex virus to the central nervous system.", "content": "Morphological studies of the neural spread of herpes simplex virus to the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195519"} {"pmid": "4195520", "title": "Comparison of various drug regimens in domiciliary chemotherapy.", "content": "Comparison of various drug regimens in domiciliary chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195520"} {"pmid": "4195521", "title": "Pneumocystis carinii infection. A cytologic, histologic, and electron microscopic study of the organism.", "content": "Pneumocystis carinii infection. A cytologic, histologic, and electron microscopic study of the organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195521"} {"pmid": "4195522", "title": "Histochemical staining of normal and Mycoplasma-infected turkey sinus epithelial cells.", "content": "Histochemical staining of normal and Mycoplasma-infected turkey sinus epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195522"} {"pmid": "4195523", "title": "Renal transplantation: present status.", "content": "Renal transplantation: present status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195523"} {"pmid": "4195526", "title": "The effect of the carrier protein on the immune response and on the induction of tolerance in mice to the 2,4-dinitrophenyl determinant.", "content": "The effect of the carrier protein on the immune response and on the induction of tolerance in mice to the 2,4-dinitrophenyl determinant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195526"} {"pmid": "4195528", "title": "Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. II. Studies with fluorescent antibody technique.", "content": "Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. II. Studies with fluorescent antibody technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195528"} {"pmid": "4195527", "title": "Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. I. Light microscopic study.", "content": "Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. I. Light microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195527"} {"pmid": "4195529", "title": "Antibody production in vitro. The effects of anti-allotypic serum on the secondary response of rabbit spleen cell suspensions to sheep erythrocytes (SRC).", "content": "Antibody production in vitro. The effects of anti-allotypic serum on the secondary response of rabbit spleen cell suspensions to sheep erythrocytes (SRC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195529"} {"pmid": "4195530", "title": "The recovery of immunological reactivity to some synthetic polypeptides containing proline after the induction of specific immunological tolerance.", "content": "The recovery of immunological reactivity to some synthetic polypeptides containing proline after the induction of specific immunological tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195530"} {"pmid": "4195532", "title": "Studies on intravitreal initiation of the immune response.", "content": "Studies on intravitreal initiation of the immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195532"} {"pmid": "4195531", "title": "Auto-allergic reactions following internal irradiation of the liver.", "content": "Auto-allergic reactions following internal irradiation of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195531"} {"pmid": "4195534", "title": "The archetypes in Peter Pan.", "content": "The archetypes in Peter Pan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195534"} {"pmid": "4195533", "title": "The symbolic attitude in psychotherapy.", "content": "The symbolic attitude in psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195533"} {"pmid": "4195537", "title": "The acid-base surface: a three-dimensional visual model for analysis of acid-base information.", "content": "The acid-base surface: a three-dimensional visual model for analysis of acid-base information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195537"} {"pmid": "4195536", "title": "Changing morphology of the uterine tubes of the domestic pig (Sus scrofa domesticus) with age.", "content": "Changing morphology of the uterine tubes of the domestic pig (Sus scrofa domesticus) with age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195536"} {"pmid": "4195538", "title": "Non-production of interfering substances by serum from patients with infectious hepatitis.", "content": "Non-production of interfering substances by serum from patients with infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195538"} {"pmid": "4195539", "title": "The significance of intermediate fibres in reinnervated human skeletal muscle.", "content": "The significance of intermediate fibres in reinnervated human skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195539"} {"pmid": "4195541", "title": "Effects of maternal dietary lipotropes on prenatal and neonatal rats.", "content": "Effects of maternal dietary lipotropes on prenatal and neonatal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195541"} {"pmid": "4195540", "title": "Ultrastructural and histochemical correlations of experimental muscle regeneration.", "content": "Ultrastructural and histochemical correlations of experimental muscle regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195540"} {"pmid": "4195543", "title": "Detection of a new serum-antigen in three epidemics of short-incubation hepatitis.", "content": "Detection of a new serum-antigen in three epidemics of short-incubation hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195543"} {"pmid": "4195542", "title": "Care and management of a chimpanzee after cross-circulation with a hepatitis patient.", "content": "Care and management of a chimpanzee after cross-circulation with a hepatitis patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195542"} {"pmid": "4195544", "title": "HL-A matching in treatment of burned patients with skin allografts.", "content": "HL-A matching in treatment of burned patients with skin allografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195544"} {"pmid": "4195535", "title": "Prenatal observations on the incisive fissure and the frontal process in man.", "content": "Prenatal observations on the incisive fissure and the frontal process in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195535"} {"pmid": "4195545", "title": "Central venous pressure in clinical management of acute gastrointestinal bleeding.", "content": "Central venous pressure in clinical management of acute gastrointestinal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195545"} {"pmid": "4195546", "title": "Stimulation of pancreatic secretion by intraduodenal infusion of bile-salts.", "content": "Stimulation of pancreatic secretion by intraduodenal infusion of bile-salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195546"} {"pmid": "4195547", "title": "Hypokalaemia in megaloblastic anaemias.", "content": "Hypokalaemia in megaloblastic anaemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195547"} {"pmid": "4195549", "title": "Short-term anaphylactic IgG antibodies in human sera.", "content": "Short-term anaphylactic IgG antibodies in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195549"} {"pmid": "4195548", "title": "Amitriptyline and cardiac disease. Risk of sudden death identified by monitoring system.", "content": "Amitriptyline and cardiac disease. Risk of sudden death identified by monitoring system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195548"} {"pmid": "4195550", "title": "Leucocyte antigens and placental sponge.", "content": "Leucocyte antigens and placental sponge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195550"} {"pmid": "4195551", "title": "The at-risk register.", "content": "The at-risk register.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195551"} {"pmid": "4195552", "title": "Lymphoid stimulation and lymphoid neoplasia.", "content": "Lymphoid stimulation and lymphoid neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195552"} {"pmid": "4195553", "title": "Urinary oestrogens in pill-users may be artefacts.", "content": "Urinary oestrogens in pill-users may be artefacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195553"} {"pmid": "4195554", "title": "Amyloidosis of Alzheimer's disease: a clue to ageing?", "content": "Amyloidosis of Alzheimer's disease: a clue to ageing?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195554"} {"pmid": "4195555", "title": "Compartmentalisation of ascitic fluid.", "content": "Compartmentalisation of ascitic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195555"} {"pmid": "4195556", "title": "Neuromuscular disorders in rheumatoid arthritis.", "content": "Neuromuscular disorders in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195556"} {"pmid": "4195557", "title": "Cutting the cost of health care.", "content": "Cutting the cost of health care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195557"} {"pmid": "4195558", "title": "Coordinated care of the child with spina bifida.", "content": "Coordinated care of the child with spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195558"} {"pmid": "4195559", "title": "Emergency call service.", "content": "Emergency call service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195559"} {"pmid": "4195560", "title": "Epidemic Shiga dysentery in Central America.", "content": "Epidemic Shiga dysentery in Central America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195560"} {"pmid": "4195561", "title": "Population policy.", "content": "Population policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195561"} {"pmid": "4195562", "title": "Sterilisation of women.", "content": "Sterilisation of women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195562"} {"pmid": "4195563", "title": "Sterilisation of women.", "content": "Sterilisation of women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195563"} {"pmid": "4195564", "title": "Royal College of Physicians of Edinburgh.", "content": "Royal College of Physicians of Edinburgh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195564"} {"pmid": "4195565", "title": "Contamination of operation wounds.", "content": "Contamination of operation wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195565"} {"pmid": "4195566", "title": "Australia antigen and hepatitis.", "content": "Australia antigen and hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195566"} {"pmid": "4195567", "title": "Australia antigen and hepatitis.", "content": "Australia antigen and hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195567"} {"pmid": "4195568", "title": "Junior hospital staff in training.", "content": "Junior hospital staff in training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195568"} {"pmid": "4195569", "title": "Thrombolytic therapy in pulmonary embolism.", "content": "Thrombolytic therapy in pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195569"} {"pmid": "4195570", "title": "Prostaglandins in fertility control.", "content": "Prostaglandins in fertility control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195570"} {"pmid": "4195571", "title": "Carrageenan and galactosaemia.", "content": "Carrageenan and galactosaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195571"} {"pmid": "4195572", "title": "Autoimmunity in diabetes mellitus.", "content": "Autoimmunity in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195572"} {"pmid": "4195573", "title": "Children in isolation units.", "content": "Children in isolation units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195573"} {"pmid": "4195574", "title": "Selection of housemen.", "content": "Selection of housemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195574"} {"pmid": "4195575", "title": "The fist as external cardiac pacemaker.", "content": "The fist as external cardiac pacemaker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195575"} {"pmid": "4195577", "title": "L-tryptophan in depression.", "content": "L-tryptophan in depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195577"} {"pmid": "4195576", "title": "L-dopa, parkinsonism, and depression.", "content": "L-dopa, parkinsonism, and depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195576"} {"pmid": "4195578", "title": "Exercise and urinary excretion of cyclic A.M.P.", "content": "Exercise and urinary excretion of cyclic A.M.P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195578"} {"pmid": "4195579", "title": "Cheese reaction during debrisoquine treatment.", "content": "Cheese reaction during debrisoquine treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195579"} {"pmid": "4195580", "title": "Post-vagotomy dysphagia.", "content": "Post-vagotomy dysphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195580"} {"pmid": "4195582", "title": "Vitamin-D treatment in hypoparathyroidism.", "content": "Vitamin-D treatment in hypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195582"} {"pmid": "4195581", "title": "Vitamin-D treatment in hypoparathyroidism.", "content": "Vitamin-D treatment in hypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195581"} {"pmid": "4195583", "title": "Tolbutamide test in pituitary disease.", "content": "Tolbutamide test in pituitary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195583"} {"pmid": "4195584", "title": "Metabolism of progestagens.", "content": "Metabolism of progestagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195584"} {"pmid": "4195585", "title": "N.B.T. test stimulated.", "content": "N.B.T. test stimulated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195585"} {"pmid": "4195587", "title": "Haemoglobin and cholesterol.", "content": "Haemoglobin and cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195587"} {"pmid": "4195586", "title": "Assessing the nutritional status of children.", "content": "Assessing the nutritional status of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195586"} {"pmid": "4195588", "title": "Stool trypsin assay.", "content": "Stool trypsin assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195588"} {"pmid": "4195589", "title": "Vaccum extraction following cord prolapse.", "content": "Vaccum extraction following cord prolapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195589"} {"pmid": "4195590", "title": "Milk-bottle problem.", "content": "Milk-bottle problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195590"} {"pmid": "4195591", "title": "Patricia Troy, L.R.C.P.I.", "content": "Patricia Troy, L.R.C.P.I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195591"} {"pmid": "4195594", "title": "Influence of ototoxic drugs on acetylcholine-induced depression of the cochlear N1 potential.", "content": "Influence of ototoxic drugs on acetylcholine-induced depression of the cochlear N1 potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195594"} {"pmid": "4195597", "title": "Maternal and child health nursing. Nursing therapy in a combined treatment approach to rumination.", "content": "Maternal and child health nursing. Nursing therapy in a combined treatment approach to rumination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195597"} {"pmid": "4195599", "title": "Allergy techniques: methods and mechanisms.", "content": "Allergy techniques: methods and mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195599"} {"pmid": "4195602", "title": "Ethanol infusions.", "content": "Ethanol infusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195602"} {"pmid": "4195603", "title": "The overhead projector as a blackboard.", "content": "The overhead projector as a blackboard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195603"} {"pmid": "4195604", "title": "Sim: the perfect patient.", "content": "Sim: the perfect patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195604"} {"pmid": "4195596", "title": "Annex I. New agglutination methods for the diagnosis of brucellosis using stained antigens.", "content": "Annex I. New agglutination methods for the diagnosis of brucellosis using stained antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195596"} {"pmid": "4195605", "title": "Carcinoma of the stomach.", "content": "Carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195605"} {"pmid": "4195606", "title": "Ringless needle holder. An aid in training of surgery residents and scrub nurses.", "content": "Ringless needle holder. An aid in training of surgery residents and scrub nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195606"} {"pmid": "4195607", "title": "Vibrios from fish pen slime which mimic Escherichia coli on violet red bile agar.", "content": "Vibrios from fish pen slime which mimic Escherichia coli on violet red bile agar. Organisms from fish pen slime which mimicked coliforms and Escherichia coli on Violet Red Bile Agar were identified as members of the genus Vibrio on the basis of metabolic and morphological characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195607"} {"pmid": "4195608", "title": "Plaque size heterogeneity: a genetic trait of lymphocytic choriomeningitis virus.", "content": "Plaque size heterogeneity: a genetic trait of lymphocytic choriomeningitis virus. All of the ten strains of lymphocytic choriomeningitis virus assayed on BHK 21/13S cells showed various degrees of plaque size heterogeneity. The amount of virus released from these plaques was usually very small because of rapid photodynamic inactivation by neutral red. When virus from large and small plaques of a specific strain was plated, the same distribution of plaque size was obtained from each clone. Although it was shown that surface virus could possibly be randomly distributed at the time of addition of neutral red overlays, no virus could be isolated from nonplaque areas. Two different strains of virus (CA1371 and WE) with markedly different plaque size ranges were separated by plaque excision from plates infected with a mixture of both viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195608"} {"pmid": "4195610", "title": "A novel technique for in situ demonstration of cell viability and cell injury on the respiratory surface of trachea explants. Brief report.", "content": "A novel technique for in situ demonstration of cell viability and cell injury on the respiratory surface of trachea explants. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195610"} {"pmid": "4195609", "title": "Morphological studies on equine arteritis virus.", "content": "Morphological studies on equine arteritis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195609"} {"pmid": "4195600", "title": "Guinea pig ovary and testis: localization of common gonad specific antigens.", "content": "Guinea pig ovary and testis: localization of common gonad specific antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195600"} {"pmid": "4195611", "title": "Detection and some characteristics of foot-and-mouth disease (FMD) antibodies in bovine saliva. Brief report.", "content": "Detection and some characteristics of foot-and-mouth disease (FMD) antibodies in bovine saliva. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195611"} {"pmid": "4195613", "title": "Polybenzoid hazards.", "content": "Polybenzoid hazards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195613"} {"pmid": "4195614", "title": "Thin-layer chromatographic identification of estrogens and progestogens in oral contraceptives.", "content": "Thin-layer chromatographic identification of estrogens and progestogens in oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195614"} {"pmid": "4195616", "title": "Investigations on the fine structure of staphylococcus in relation to its multiplication phases.", "content": "Investigations on the fine structure of staphylococcus in relation to its multiplication phases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195616"} {"pmid": "4195618", "title": "Pituitary-adrenal responsiveness during prolonged administration of estrogen and 17-acetoxy-progesterone derived progestin.", "content": "Pituitary-adrenal responsiveness during prolonged administration of estrogen and 17-acetoxy-progesterone derived progestin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195618"} {"pmid": "4195620", "title": "Eosinophil leukocytes in inflammatory exudate.", "content": "Eosinophil leukocytes in inflammatory exudate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195620"} {"pmid": "4195621", "title": "Immunosuppressive treatment of bronchial asthma.", "content": "Immunosuppressive treatment of bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195621"} {"pmid": "4195622", "title": "Electron microscopy study of the pox-like virus of Melolontha melolontha L(Coleoptera, Scarabeidae). Virus morphogenesis.", "content": "Electron microscopy study of the pox-like virus of Melolontha melolontha L(Coleoptera, Scarabeidae). Virus morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195622"} {"pmid": "4195623", "title": "Physicochemical studies of equine infectionus anemia virus. 3. Purification and electron microscopic observation of the virus.", "content": "Physicochemical studies of equine infectionus anemia virus. 3. Purification and electron microscopic observation of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195623"} {"pmid": "4195624", "title": "Characterization of bovine viral diarrhea viruses. V. Morphology of characteristic particles studied by electron microscopy.", "content": "Characterization of bovine viral diarrhea viruses. V. Morphology of characteristic particles studied by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195624"} {"pmid": "4195625", "title": "Electron microscopic studies on bovine ephemeral fever virus.", "content": "Electron microscopic studies on bovine ephemeral fever virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195625"} {"pmid": "4195626", "title": "Electron microscopic observations of equine infectious anemia (EIA) virus in cultivated horse leukocytes. (Brief report).", "content": "Electron microscopic observations of equine infectious anemia (EIA) virus in cultivated horse leukocytes. (Brief report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195626"} {"pmid": "4195627", "title": "A respiratory syncytial virus of bovine origin.", "content": "A respiratory syncytial virus of bovine origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195627"} {"pmid": "4195631", "title": "Selective staining of degenerating axons in the central nervous system by a simplified silver method: spinal cord projections to external cuneate and inferior olivary nuclei in the cat.", "content": "Selective staining of degenerating axons in the central nervous system by a simplified silver method: spinal cord projections to external cuneate and inferior olivary nuclei in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195631"} {"pmid": "4195629", "title": "Virus-like particles occurring in cultures of stable pig kidney cell lines. Brief report.", "content": "Virus-like particles occurring in cultures of stable pig kidney cell lines. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195629"} {"pmid": "4195630", "title": "Disappointments in the management of patients with malignancy of pancreas, duodenum, and common bile duct.", "content": "Disappointments in the management of patients with malignancy of pancreas, duodenum, and common bile duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195630"} {"pmid": "4195632", "title": "Ultrastructural localization of acid phosphatase in synaptic terminals of the rat substantia gelatinosa Rolandi.", "content": "Ultrastructural localization of acid phosphatase in synaptic terminals of the rat substantia gelatinosa Rolandi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195632"} {"pmid": "4195634", "title": "Methods in pancreatitis research using living acinar cells.", "content": "Methods in pancreatitis research using living acinar cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195634"} {"pmid": "4195635", "title": "Presence of gammaE in nasal washings and sputum from asthmatic patients.", "content": "Presence of gammaE in nasal washings and sputum from asthmatic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195635"} {"pmid": "4195636", "title": "Hypersensitivity responses in monkeys. IV. Sensitization to human serum and nonacceptance of reagin.", "content": "Hypersensitivity responses in monkeys. IV. Sensitization to human serum and nonacceptance of reagin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195636"} {"pmid": "4195637", "title": "Immunologic studies on aspirin. Clinical studies with aspiryl-protein conjugates.", "content": "Immunologic studies on aspirin. Clinical studies with aspiryl-protein conjugates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195637"} {"pmid": "4195643", "title": "Corneal immune globulin distribution.", "content": "Corneal immune globulin distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195643"} {"pmid": "4195642", "title": "Toxicity of the cyanoacrylates.", "content": "Toxicity of the cyanoacrylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195642"} {"pmid": "4195645", "title": "Slow evoked cortical potentials and temporal features of stimulation.", "content": "Slow evoked cortical potentials and temporal features of stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195645"} {"pmid": "4195647", "title": "Dynamic characteristics of visual evoked potentials in the dog. I. Cortical and subcortical potentials evoked by sine wave modulated light.", "content": "Dynamic characteristics of visual evoked potentials in the dog. I. Cortical and subcortical potentials evoked by sine wave modulated light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195647"} {"pmid": "4195648", "title": "Dynamic characteristics of visual evoked potentials in the dog. II. Beta frequency selectivity in evoked potentials and background activity.", "content": "Dynamic characteristics of visual evoked potentials in the dog. II. Beta frequency selectivity in evoked potentials and background activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195648"} {"pmid": "4195649", "title": "Chemical sensitivity of neurons in long-isolated slabs of cat cerebral cortex.", "content": "Chemical sensitivity of neurons in long-isolated slabs of cat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195649"} {"pmid": "4195650", "title": "Inhibition and paroxysmal activity in long-isolated cortical slabs.", "content": "Inhibition and paroxysmal activity in long-isolated cortical slabs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195650"} {"pmid": "4195652", "title": "Naso-ethmoidal electrode for recording the electrical activity of the inferior surface of the frontal lobe.", "content": "Naso-ethmoidal electrode for recording the electrical activity of the inferior surface of the frontal lobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195652"} {"pmid": "4195653", "title": "EEG analysis based on time domain properties.", "content": "EEG analysis based on time domain properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195653"} {"pmid": "4195654", "title": "A digitally controlled constant current stimulator.", "content": "A digitally controlled constant current stimulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195654"} {"pmid": "4195655", "title": "An improved write-out system for low frequency wave analysers.", "content": "An improved write-out system for low frequency wave analysers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195655"} {"pmid": "4195656", "title": "Electroencephalographic features of posterior fossa tumours in children.", "content": "Electroencephalographic features of posterior fossa tumours in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195656"} {"pmid": "4195657", "title": "Changes in the ventricular system and the EEG 24 hours after pneumoencephalography.", "content": "Changes in the ventricular system and the EEG 24 hours after pneumoencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195657"} {"pmid": "4195658", "title": "Traumatic generalized changes in the EEG.", "content": "Traumatic generalized changes in the EEG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195658"} {"pmid": "4195659", "title": "Unusual EEG findings with subdural hematoma in a child.", "content": "Unusual EEG findings with subdural hematoma in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195659"} {"pmid": "4195660", "title": "Frequency analysis studies on the sleep EEG of older infants.", "content": "Frequency analysis studies on the sleep EEG of older infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195660"} {"pmid": "4195661", "title": "Treatment of tetanus.", "content": "Treatment of tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195661"} {"pmid": "4195662", "title": "A method to determine the efficiency of anti-epileptic drugs on experimental cortical seizures.", "content": "A method to determine the efficiency of anti-epileptic drugs on experimental cortical seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195662"} {"pmid": "4195663", "title": "Narcotic and excitatory phenomena influenced by the analgesic Fentanyl.", "content": "Narcotic and excitatory phenomena influenced by the analgesic Fentanyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195663"} {"pmid": "4195664", "title": "The EEG of congenitally blind adults.", "content": "The EEG of congenitally blind adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195664"} {"pmid": "4195666", "title": "A micro-electrode technique for the comparison of micro-electroencephalograms.", "content": "A micro-electrode technique for the comparison of micro-electroencephalograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195666"} {"pmid": "4195665", "title": "Evoked potentials of different sense modalities in the human thalamus.", "content": "Evoked potentials of different sense modalities in the human thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195665"} {"pmid": "4195667", "title": "Fatigue as a neurological syndrome.", "content": "Fatigue as a neurological syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195667"} {"pmid": "4195668", "title": "Pseudomyotonia.", "content": "Pseudomyotonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195668"} {"pmid": "4195670", "title": "Ultrasound measurements.", "content": "Ultrasound measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195670"} {"pmid": "4195669", "title": "Movements of cerebral structures.", "content": "Movements of cerebral structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195669"} {"pmid": "4195671", "title": "Surface marking cerebral structures in echo-encephalography.", "content": "Surface marking cerebral structures in echo-encephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195671"} {"pmid": "4195672", "title": "Reflex amplitudes and increasing mental load.", "content": "Reflex amplitudes and increasing mental load.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195672"} {"pmid": "4195673", "title": "Depth electrographic observations in an epileptic patient.", "content": "Depth electrographic observations in an epileptic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195673"} {"pmid": "4195674", "title": "Effects of acute marijuana smoking on the EEG.", "content": "Effects of acute marijuana smoking on the EEG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195674"} {"pmid": "4195675", "title": "Interrelationships of form and latency of spike discharge from small areas of human cortex.", "content": "Interrelationships of form and latency of spike discharge from small areas of human cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195675"} {"pmid": "4195677", "title": "The EEG in deaf children.", "content": "The EEG in deaf children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195677"} {"pmid": "4195676", "title": "EEG study of maturation in the puppy: photic stimulation and CO2.", "content": "EEG study of maturation in the puppy: photic stimulation and CO2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195676"} {"pmid": "4195678", "title": "Analysis of hippocampal influence on units of mammillary region in awake, sitting squirrel monkeys.", "content": "Analysis of hippocampal influence on units of mammillary region in awake, sitting squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195678"} {"pmid": "4195680", "title": "Focal high voltage beta activity: clinical correlations.", "content": "Focal high voltage beta activity: clinical correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195680"} {"pmid": "4195679", "title": "Cerebellar induced effects recorded in the cochlear nucleus of the cat.", "content": "Cerebellar induced effects recorded in the cochlear nucleus of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195679"} {"pmid": "4195681", "title": "Regional permeability changes in experimental convulsive disorder.", "content": "Regional permeability changes in experimental convulsive disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195681"} {"pmid": "4195682", "title": "Phasic changes in level of the integrated dark discharge during spontaneous saccades.", "content": "Phasic changes in level of the integrated dark discharge during spontaneous saccades.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195682"} {"pmid": "4195684", "title": "Simultaneous bilateral summated cortical responses to single and to variably delayed median nerve stimulation.", "content": "Simultaneous bilateral summated cortical responses to single and to variably delayed median nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195684"} {"pmid": "4195685", "title": "Evoked responses in Down's syndrome of young adults.", "content": "Evoked responses in Down's syndrome of young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195685"} {"pmid": "4195683", "title": "Lateralized EEG changes after induced convulsions.", "content": "Lateralized EEG changes after induced convulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195683"} {"pmid": "4195686", "title": "EEG in Kleine-Levin syndrome.", "content": "EEG in Kleine-Levin syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195686"} {"pmid": "4195689", "title": "XYY and XXY inmates of security prison: EEG findings.", "content": "XYY and XXY inmates of security prison: EEG findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195689"} {"pmid": "4195687", "title": "EEG findings in hydrocephalic patients with shunt procedures.", "content": "EEG findings in hydrocephalic patients with shunt procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195687"} {"pmid": "4195688", "title": "Hypsarrhythmic EEG patterns in the first year of life: a 6-12 year clinical outcome.", "content": "Hypsarrhythmic EEG patterns in the first year of life: a 6-12 year clinical outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195688"} {"pmid": "4195690", "title": "Late brain recovery processes after drug overdose.", "content": "Late brain recovery processes after drug overdose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195690"} {"pmid": "4195691", "title": "Occipital spikes during photic stimulation and their relation to visual evoked responses in photosensitive epilepsy.", "content": "Occipital spikes during photic stimulation and their relation to visual evoked responses in photosensitive epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195691"} {"pmid": "4195692", "title": "The use of the autoregressive model in EEG analysis.", "content": "The use of the autoregressive model in EEG analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195692"} {"pmid": "4195694", "title": "The effect of stimulus context on evoked responses in human frontal cortex.", "content": "The effect of stimulus context on evoked responses in human frontal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195694"} {"pmid": "4195693", "title": "Electro-clinical features of 50 children with tuberose sclerosis.", "content": "Electro-clinical features of 50 children with tuberose sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195693"} {"pmid": "4195695", "title": "Investigations for the development of a model of an epileptic process.", "content": "Investigations for the development of a model of an epileptic process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195695"} {"pmid": "4195696", "title": "Polarity and distribution of human visual evoked potential (VEP) components as clues to cortical topography.", "content": "Polarity and distribution of human visual evoked potential (VEP) components as clues to cortical topography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195696"} {"pmid": "4195698", "title": "The dendritic tree of spinal neurons.", "content": "The dendritic tree of spinal neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195698"} {"pmid": "4195699", "title": "Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans.", "content": "Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195699"} {"pmid": "4195702", "title": "Effects of gamma-globulin with vaccines used with routine immunizations.", "content": "Effects of gamma-globulin with vaccines used with routine immunizations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195702"} {"pmid": "4195723", "title": "The effects of various physical activity levels and dietary carbohydrate source on rat cholesterol levels.", "content": "The effects of various physical activity levels and dietary carbohydrate source on rat cholesterol levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195723"} {"pmid": "4195724", "title": "Sarcomas after inoculation of newborn hamsters with Herpes virus hominis type 2 strains.", "content": "Sarcomas after inoculation of newborn hamsters with Herpes virus hominis type 2 strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195724"} {"pmid": "4195725", "title": "Iron in the lactating mammary gland of the rat.", "content": "Iron in the lactating mammary gland of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195725"} {"pmid": "4195726", "title": "Reactions of proinsulin and its derivatives with antibodies to insulin.", "content": "Reactions of proinsulin and its derivatives with antibodies to insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195726"} {"pmid": "4195728", "title": "Antibodies to homologous RNA in the rabbit following stimulation by exogenous RNA.", "content": "Antibodies to homologous RNA in the rabbit following stimulation by exogenous RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195728"} {"pmid": "4195727", "title": "Production of heparin related mucopolysaccharides by mammalian cells in culture.", "content": "Production of heparin related mucopolysaccharides by mammalian cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195727"} {"pmid": "4195730", "title": "Diffusion of epsilon aminocaproic acid to the joints.", "content": "Diffusion of epsilon aminocaproic acid to the joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195730"} {"pmid": "4195729", "title": "Antibody-forming cells in five organs of hyperimmunized guinea pigs.", "content": "Antibody-forming cells in five organs of hyperimmunized guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195729"} {"pmid": "4195731", "title": "Metabolic neuropathies and myopathies in infancy and childhood.", "content": "Metabolic neuropathies and myopathies in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195731"} {"pmid": "4195732", "title": "Uraemic polyneuropathy.", "content": "Uraemic polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195732"} {"pmid": "4195737", "title": "Virus-specific immunofluorescent and precipitin antigens and cell-free virus in the tissues of birds infected with Marek's disease.", "content": "Virus-specific immunofluorescent and precipitin antigens and cell-free virus in the tissues of birds infected with Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195737"} {"pmid": "4195746", "title": "Correlation of thyroid-function studies.", "content": "Correlation of thyroid-function studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195746"} {"pmid": "4195747", "title": "The regeneration gradients and the effects of budding, feeding, actinomycin and R Nase on reconstitution in Hydra attenuata Pall.", "content": "The regeneration gradients and the effects of budding, feeding, actinomycin and R Nase on reconstitution in Hydra attenuata Pall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195747"} {"pmid": "4195739", "title": "Monoclonal immunoglobulins.", "content": "Monoclonal immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195739"} {"pmid": "4195741", "title": "Immunoglobulins in asthma.", "content": "Immunoglobulins in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195741"} {"pmid": "4195740", "title": "Cell-mediated immunity. Antigenic specificity.", "content": "Cell-mediated immunity. Antigenic specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195740"} {"pmid": "4195738", "title": "Antibodies. Structure and function of immunoglobulins.", "content": "Antibodies. Structure and function of immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195738"} {"pmid": "4195744", "title": "Antigenic determinants and antibody complementarity.", "content": "Antigenic determinants and antibody complementarity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195744"} {"pmid": "4195743", "title": "Animal models of allergic diseases. Monkeys.", "content": "Animal models of allergic diseases. Monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195743"} {"pmid": "4195742", "title": "The allergic response of rabbit leukocytes and platelets.", "content": "The allergic response of rabbit leukocytes and platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195742"} {"pmid": "4195755", "title": "Coagulation and fibrinolytic studies during continuous use of low dose gestagen.", "content": "Coagulation and fibrinolytic studies during continuous use of low dose gestagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195755"} {"pmid": "4195756", "title": "Bedside diagnosis of arrhythmias.", "content": "Bedside diagnosis of arrhythmias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195756"} {"pmid": "4195758", "title": "Esophagogastrectomy versus radiation therapy for midesophageal carcinoma.", "content": "Esophagogastrectomy versus radiation therapy for midesophageal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195758"} {"pmid": "4195745", "title": "Mechanism of drug action in the therapy of respiratory allergy.", "content": "Mechanism of drug action in the therapy of respiratory allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195745"} {"pmid": "4195759", "title": "Extracorporeal circulation for support of palliative cardiac surgery in infants.", "content": "Extracorporeal circulation for support of palliative cardiac surgery in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195759"} {"pmid": "4195760", "title": "Proposed guidelines for protocol studies. II. Plasma cell myeloma. Prepared by a Committee of the Chronic Leukemia--Myeloma Task Force, National Cancer Institute.", "content": "Proposed guidelines for protocol studies. II. Plasma cell myeloma. Prepared by a Committee of the Chronic Leukemia--Myeloma Task Force, National Cancer Institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195760"} {"pmid": "4195761", "title": "Development of new instructional materials in the IMC network.", "content": "Development of new instructional materials in the IMC network.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195761"} {"pmid": "4195763", "title": "Combinations of agents which induce ATP energized mitochondrial volume changes.", "content": "Combinations of agents which induce ATP energized mitochondrial volume changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195763"} {"pmid": "4195762", "title": "Immunochemical studies on the serum, intestinal secretions and intestinal mucosa in patients with adult celiac disease and other forms of the celiac syndrome.", "content": "Immunochemical studies on the serum, intestinal secretions and intestinal mucosa in patients with adult celiac disease and other forms of the celiac syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195762"} {"pmid": "4195764", "title": "Aminoalkenylbenzenesulfonamides with hypotensive and histamine-releasing properties.", "content": "Aminoalkenylbenzenesulfonamides with hypotensive and histamine-releasing properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195764"} {"pmid": "4195765", "title": "The demonstration of recent myocardial injury: a simple method suitable for routine use.", "content": "The demonstration of recent myocardial injury: a simple method suitable for routine use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195765"} {"pmid": "4195767", "title": "Hepatitis-associated antigen in Ugandan patients with hepatocellular carcinoma.", "content": "Hepatitis-associated antigen in Ugandan patients with hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195767"} {"pmid": "4195768", "title": "Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism.", "content": "Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195768"} {"pmid": "4195769", "title": "Extraskeletal calcification complicating oral neutral-phosphate therapy.", "content": "Extraskeletal calcification complicating oral neutral-phosphate therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195769"} {"pmid": "4195770", "title": "Impaired fibrinolytic response to exercise in patients with type-IV hyperlipoproteinaemia.", "content": "Impaired fibrinolytic response to exercise in patients with type-IV hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195770"} {"pmid": "4195771", "title": "Leucocyte phenotypes in Hodgkin's disease.", "content": "Leucocyte phenotypes in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195771"} {"pmid": "4195772", "title": "Duplication of alpha-thalassaemia gene in three Greek families with haemoglobin H disease.", "content": "Duplication of alpha-thalassaemia gene in three Greek families with haemoglobin H disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195772"} {"pmid": "4195773", "title": "B.C.G. vaccination and leukemia mortality.", "content": "B.C.G. vaccination and leukemia mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195773"} {"pmid": "4195775", "title": "To weigh and to consider.", "content": "To weigh and to consider.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195775"} {"pmid": "4195774", "title": "Amyloidosis: an expression of immunological tolerance?", "content": "Amyloidosis: an expression of immunological tolerance?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195774"} {"pmid": "4195776", "title": "Screening outpatients for hyperaldosteronism.", "content": "Screening outpatients for hyperaldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195776"} {"pmid": "4195777", "title": "Uneasy present, uncertain future.", "content": "Uneasy present, uncertain future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195777"} {"pmid": "4195778", "title": "Renal disease in old people.", "content": "Renal disease in old people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195778"} {"pmid": "4195779", "title": "Psychological effects of subarachnoid haemorrhage.", "content": "Psychological effects of subarachnoid haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195779"} {"pmid": "4195780", "title": "The patient's tight.", "content": "The patient's tight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195780"} {"pmid": "4195781", "title": "The world's poliomyelitis.", "content": "The world's poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195781"} {"pmid": "4195782", "title": "Preoperative and postoperative physiotherapy.", "content": "Preoperative and postoperative physiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195782"} {"pmid": "4195783", "title": "Paying for medical care. Need for debate.", "content": "Paying for medical care. Need for debate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195783"} {"pmid": "4195785", "title": "Intradermal test and serological tests in suspected brucella infection in man.", "content": "Intradermal test and serological tests in suspected brucella infection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195785"} {"pmid": "4195786", "title": "Coping with incontinence in the home.", "content": "Coping with incontinence in the home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195786"} {"pmid": "4195784", "title": "Deaths in United Kingdom opioid users 1965-69.", "content": "Deaths in United Kingdom opioid users 1965-69.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195784"} {"pmid": "4195787", "title": "Screening for breast and gynaecological lesions.", "content": "Screening for breast and gynaecological lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195787"} {"pmid": "4195788", "title": "Legal abortion and social class.", "content": "Legal abortion and social class.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195788"} {"pmid": "4195789", "title": "Ineffectiveness of L-dopa as supplement to penicillamine in a case of Wilson's disease.", "content": "Ineffectiveness of L-dopa as supplement to penicillamine in a case of Wilson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195789"} {"pmid": "4195790", "title": "Side-effects of L-dopa in postencephalitic parkinsonism.", "content": "Side-effects of L-dopa in postencephalitic parkinsonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195790"} {"pmid": "4195791", "title": "L-dopa plus decarboxylase inhibitor in depression.", "content": "L-dopa plus decarboxylase inhibitor in depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195791"} {"pmid": "4195792", "title": "Smoking and frusemide diuresis.", "content": "Smoking and frusemide diuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195792"} {"pmid": "4195794", "title": "Epidemic shiga dysentery in Central America.", "content": "Epidemic shiga dysentery in Central America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195794"} {"pmid": "4195793", "title": "Long-term hepatic support.", "content": "Long-term hepatic support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195793"} {"pmid": "4195795", "title": "The beta-blocking effect of practolol in asthmatics.", "content": "The beta-blocking effect of practolol in asthmatics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195795"} {"pmid": "4195796", "title": "Maternity service.", "content": "Maternity service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195796"} {"pmid": "4195797", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195797"} {"pmid": "4195798", "title": "Fetoprotein in pregnant African women.", "content": "Fetoprotein in pregnant African women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195798"} {"pmid": "4195799", "title": "Contamination of meat carcasses.", "content": "Contamination of meat carcasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195799"} {"pmid": "4195800", "title": "Sleep-walking in twins.", "content": "Sleep-walking in twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195800"} {"pmid": "4195801", "title": "Effect of tyrosine on plasma-I.R.I.", "content": "Effect of tyrosine on plasma-I.R.I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195801"} {"pmid": "4195802", "title": "Circulating heparin-like anticoagulant following portacaval anastomosis.", "content": "Circulating heparin-like anticoagulant following portacaval anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195802"} {"pmid": "4195803", "title": "Criteria of rheumatic fever.", "content": "Criteria of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195803"} {"pmid": "4195804", "title": "Silastic sheeting for abdominal-wall defects.", "content": "Silastic sheeting for abdominal-wall defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195804"} {"pmid": "4195805", "title": "Pingelap eye disease.", "content": "Pingelap eye disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195805"} {"pmid": "4195806", "title": "46, XY female: anti-androgenic effect of oral contraceptive?", "content": "46, XY female: anti-androgenic effect of oral contraceptive?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195806"} {"pmid": "4195807", "title": "Fluid-balance charts.", "content": "Fluid-balance charts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195807"} {"pmid": "4195808", "title": "Glucose-6-phosphate-dehydrogenase deficiency and age.", "content": "Glucose-6-phosphate-dehydrogenase deficiency and age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195808"} {"pmid": "4195809", "title": "Pathogenesis of the glomerular lesions in acute pancreatitis.", "content": "Pathogenesis of the glomerular lesions in acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195809"} {"pmid": "4195811", "title": "Lithium depletion and atherosclerotic heart-disease.", "content": "Lithium depletion and atherosclerotic heart-disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195811"} {"pmid": "4195810", "title": "Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin.", "content": "Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195810"} {"pmid": "4195812", "title": "Down's syndrome and presbyacousis.", "content": "Down's syndrome and presbyacousis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195812"} {"pmid": "4195813", "title": "Acute myeloid leukaemia after treatment with cytostatic agents.", "content": "Acute myeloid leukaemia after treatment with cytostatic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195813"} {"pmid": "4195814", "title": "Evolution of an atypical case of Burkitt lymphoma.", "content": "Evolution of an atypical case of Burkitt lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195814"} {"pmid": "4195815", "title": "The at-risk register.", "content": "The at-risk register.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195815"} {"pmid": "4195816", "title": "Venereal disease.", "content": "Venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195816"} {"pmid": "4195817", "title": "Tests for syphilis in children for adoption.", "content": "Tests for syphilis in children for adoption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195817"} {"pmid": "4195818", "title": "Epidemiology of gallstone disease.", "content": "Epidemiology of gallstone disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195818"} {"pmid": "4195820", "title": "Variability in urinary creatinine.", "content": "Variability in urinary creatinine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195820"} {"pmid": "4195819", "title": "Negative Coombs tests in Chinese on methyldopa.", "content": "Negative Coombs tests in Chinese on methyldopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195819"} {"pmid": "4195821", "title": "Arthur Doyne Courtenay Bell, D.M. Oxon., F.R.C.P.", "content": "Arthur Doyne Courtenay Bell, D.M. Oxon., F.R.C.P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195821"} {"pmid": "4195825", "title": "Amino acid sequence similarities in two human anti gamma globulin antibodies.", "content": "Amino acid sequence similarities in two human anti gamma globulin antibodies. Certain individuals with hypergammaglobulinemic purpura contain in their serum anti gamma globulins of restricted heterogeneity. These antibodies, characteristically of the gammaG type, were isolated from two unrelated individuals and their light polypeptide chains were subjected to amino acid sequence analysis. Although these anti gamma globulin antibodies conform to the basic VK(1) sequence, substitutions not previously encountered were found in five positions. The two antibodies were identical with each other up to residue 40 from the N-terminus of the light chains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195825"} {"pmid": "4195824", "title": "Correction of celluar metachromasia in cultured fibroblasts in several inherited mucopolysaccharidoses.", "content": "Correction of celluar metachromasia in cultured fibroblasts in several inherited mucopolysaccharidoses. Cultured fibroblasts from the genetic mucopolysaccharidoses store higher than normal amounts of the polyanionic glycosaminoglycans (mucopolysaccharides); histochemical staining with the cationic dyes toluidine blue O and Alcian blue detects such intracellular accumulation. With these stains as phenotypic markers, correction of the cellular abnormality by fibroblasts derived from different patients and their heterozygous parents has been observed among several genetic types of mucopolysaccharidoses. In this way, syndromes previously considered clinically homogeneous have been separated into distinct groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195824"} {"pmid": "4195835", "title": "An ultrastructural investigation of calcium-dependent granules in the rat neuropil.", "content": "An ultrastructural investigation of calcium-dependent granules in the rat neuropil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195835"} {"pmid": "4195836", "title": "Demonstration of degenerating climbing fibres in the molecular layer of the cerebellum.", "content": "Demonstration of degenerating climbing fibres in the molecular layer of the cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195836"} {"pmid": "4195837", "title": "Staining of experimentally-induced chorio-retinal lesions with Disulphine blue and Evans blue.", "content": "Staining of experimentally-induced chorio-retinal lesions with Disulphine blue and Evans blue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195837"} {"pmid": "4195838", "title": "New data and concepts concerning the ventricular gradient.", "content": "New data and concepts concerning the ventricular gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195838"} {"pmid": "4195839", "title": "Effect of r-epinephrine-impregnated retraction cord on the cardiovascular system.", "content": "Effect of r-epinephrine-impregnated retraction cord on the cardiovascular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195839"} {"pmid": "4195832", "title": "Improved methods for calcium and magnesium in epidermis.", "content": "Improved methods for calcium and magnesium in epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195832"} {"pmid": "4195844", "title": "Cognitive factors in perceptual dysfunction.", "content": "Cognitive factors in perceptual dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195844"} {"pmid": "4195845", "title": "Developmental dyslexia: a constitutional disorder of symbolic perception.", "content": "Developmental dyslexia: a constitutional disorder of symbolic perception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195845"} {"pmid": "4195851", "title": "The cardio-thoracic unit. Tan Tock Seng Hospital.", "content": "The cardio-thoracic unit. Tan Tock Seng Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195851"} {"pmid": "4195850", "title": "Kinins, kininogen and kininogenase activity in pregnancy and hepatic failure.", "content": "Kinins, kininogen and kininogenase activity in pregnancy and hepatic failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195850"} {"pmid": "4195852", "title": "The Golgi apparatus in chick corneal epithelium: changes in intracellular position during development.", "content": "The Golgi apparatus in chick corneal epithelium: changes in intracellular position during development. The intracellular position of the Golgi apparatuses in the basal cell layer of the corneal epithelium in embryonic and hatched chicks has been studied in the light microscope by impregnating the Golgi apparatus with silver. During two distinct periods in development the Golgi apparatuses in the basal cells shift from an apical to basal position. Each of these periods correlates in time with the appearance of an acellular collagenous matrix beneath the epithelium. Examination of the basal epithelial cells in the electron microscope confirms the intracellular shifts in position of the Golgi apparatus. The results suggest that the Golgi apparatus shifts to the basal cell pole of the corneal epithelium in order to excrete connective tissue materials into the developing corneal stroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195852"} {"pmid": "4195853", "title": "Low-resistance junctions between cancer cells in various solid tumors.", "content": "Low-resistance junctions between cancer cells in various solid tumors. Electrical coupling, which reveals the presence of specialized low-resistance intercellular junctions, has now been found in four types of tumors, Sarcoma 180, Novikoff hepatoma, and Morris hepatomas 3924-A and 7777. Coupled cancer cells were distinguished from coupled normal cells by intracellular marking techniques. Although the evidence suggests that coupling may be extensive in some cases, it is not possible to say that the coupling was normal. In particular, the results do not exclude less obvious defects in the specialized junctions, such as abnormal distribution or decreased permeability to molecules other than small inorganic ions. The results are discussed in relation to previous studies of coupling in Novikoff hepatomas and in cultures of S1801 and II cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195853"} {"pmid": "4195855", "title": "The structure of collagen--an X-ray study.", "content": "The structure of collagen--an X-ray study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195855"} {"pmid": "4195854", "title": "Substructure of microtubules in brain nerve cells as revealed by ruthenium red.", "content": "Substructure of microtubules in brain nerve cells as revealed by ruthenium red.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195854"} {"pmid": "4195856", "title": "What price non-touch technique?", "content": "What price non-touch technique?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195856"} {"pmid": "4195857", "title": "The ultrastructure of the skin of human embryos. VII. Formation of the apocrine gland.", "content": "The ultrastructure of the skin of human embryos. VII. Formation of the apocrine gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195857"} {"pmid": "4195858", "title": "Epidermal multinucleated giant cell in parapsoriasis guttata and eczematous dermatitis.", "content": "Epidermal multinucleated giant cell in parapsoriasis guttata and eczematous dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195858"} {"pmid": "4195861", "title": "Experimental pruritus in the unaffected skin of patients with different itching dermatoses.", "content": "Experimental pruritus in the unaffected skin of patients with different itching dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195861"} {"pmid": "4195860", "title": "Plethysmographic recordings of skin pulses. II. Piezoelectric and photoelectric measurements in psoriasis.", "content": "Plethysmographic recordings of skin pulses. II. Piezoelectric and photoelectric measurements in psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195860"} {"pmid": "4195862", "title": "Studies on histamine release from skin and from peritoneal mast cells of the rat induced by heat.", "content": "Studies on histamine release from skin and from peritoneal mast cells of the rat induced by heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195862"} {"pmid": "4195859", "title": "Skin clearance of iontophoretically administered chromium (51Cr) and sodium (22Na) ions in the guinea pig.", "content": "Skin clearance of iontophoretically administered chromium (51Cr) and sodium (22Na) ions in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195859"} {"pmid": "4195863", "title": "Lymph-node permeability factor: a mediator in delayed hypersensitivity? Experiments using the skin window technique.", "content": "Lymph-node permeability factor: a mediator in delayed hypersensitivity? Experiments using the skin window technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195863"} {"pmid": "4195864", "title": "Delayed reactivity to bacterial and viral extract(s) in different dermatoses.", "content": "Delayed reactivity to bacterial and viral extract(s) in different dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195864"} {"pmid": "4195865", "title": "Terminology of contact dermatitis.", "content": "Terminology of contact dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195865"} {"pmid": "4195866", "title": "Lupus erythematosus. Analysis of the sex- and age-distributions of the discoid and systemic forms of the disease in different countries.", "content": "Lupus erythematosus. Analysis of the sex- and age-distributions of the discoid and systemic forms of the disease in different countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195866"} {"pmid": "4195868", "title": "The use of standard serological tests for syphilis in screening for auto-immune connective tissue disease. Chronic biological false-positive reactions and anticomplementary activity.", "content": "The use of standard serological tests for syphilis in screening for auto-immune connective tissue disease. Chronic biological false-positive reactions and anticomplementary activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195868"} {"pmid": "4195867", "title": "Linear telangiectasia.", "content": "Linear telangiectasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195867"} {"pmid": "4195870", "title": "Benign gonococcal sepsis. A report of 36 cases.", "content": "Benign gonococcal sepsis. A report of 36 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195870"} {"pmid": "4195871", "title": "Sensitivity to antibiotics of N. gonorrhoeae isolated in 1966 and 1968 from patients in North Sweden.", "content": "Sensitivity to antibiotics of N. gonorrhoeae isolated in 1966 and 1968 from patients in North Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195871"} {"pmid": "4195869", "title": "Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise.", "content": "Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195869"} {"pmid": "4195873", "title": "The American Association of Orthodontists Audio-Visual Library.", "content": "The American Association of Orthodontists Audio-Visual Library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195873"} {"pmid": "4195872", "title": "Studies on the serum binding of vitamin B 12 in the newborn human infant.", "content": "Studies on the serum binding of vitamin B 12 in the newborn human infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195872"} {"pmid": "4195874", "title": "Effect of epsilon aminocaproic acid (EACA) on lysis of subcutaneous clots.", "content": "Effect of epsilon aminocaproic acid (EACA) on lysis of subcutaneous clots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195874"} {"pmid": "4195875", "title": "The neural control of the contractile mechanism in skeletal muscle.", "content": "The neural control of the contractile mechanism in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195875"} {"pmid": "4195877", "title": "Totipotency, variation and clonal development of cultured cells.", "content": "Totipotency, variation and clonal development of cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195877"} {"pmid": "4195878", "title": "The pineal gland.", "content": "The pineal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195878"} {"pmid": "4195880", "title": "OR technicians. 1.", "content": "OR technicians. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195880"} {"pmid": "4195876", "title": "Morphactins.", "content": "Morphactins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195876"} {"pmid": "4195883", "title": "Fetal erythrocytes in maternal circulation after spontaneous abortion.", "content": "Fetal erythrocytes in maternal circulation after spontaneous abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195883"} {"pmid": "4195882", "title": "The mechanism of action of gonadotrophic hormones in amphibians: the stimulation of delta5-3beta-hydroxysteroid dehydrogenase activity in testes of Xenopus laevis Daudin.", "content": "The mechanism of action of gonadotrophic hormones in amphibians: the stimulation of delta5-3beta-hydroxysteroid dehydrogenase activity in testes of Xenopus laevis Daudin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195882"} {"pmid": "4195881", "title": "Electron microscopic study of intranuclear glycogen.", "content": "Electron microscopic study of intranuclear glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195881"} {"pmid": "4195884", "title": "Functional autonomy in multinodular goiter.", "content": "Functional autonomy in multinodular goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195884"} {"pmid": "4195885", "title": "Mycoplasma and rheumatoid arthritis.", "content": "Mycoplasma and rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195885"} {"pmid": "4195891", "title": "Studies of histamine release from human leukocytes.", "content": "Studies of histamine release from human leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195891"} {"pmid": "4195890", "title": "Role of the thyroid hormone system in suppression of anaphylaxis due to electrolytic lesion of the tuberal region of the hypothalamus.", "content": "Role of the thyroid hormone system in suppression of anaphylaxis due to electrolytic lesion of the tuberal region of the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195890"} {"pmid": "4195894", "title": "Nonspecific passive desensitization. XVI. Type O gamma globulin prevents desensitization by types A, B and AB gamma globulins.", "content": "Nonspecific passive desensitization. XVI. Type O gamma globulin prevents desensitization by types A, B and AB gamma globulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195894"} {"pmid": "4195893", "title": "Abnormal eosinophils, eosinophilia and basophilia in methimazole neutropenia.", "content": "Abnormal eosinophils, eosinophilia and basophilia in methimazole neutropenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195893"} {"pmid": "4195892", "title": "Effectiveness of topical nasal decongestants.", "content": "Effectiveness of topical nasal decongestants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195892"} {"pmid": "4195895", "title": "The role of audio-visual aids in education.", "content": "The role of audio-visual aids in education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195895"} {"pmid": "4195889", "title": "The relationship of complement to allergic disease.", "content": "The relationship of complement to allergic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195889"} {"pmid": "4195900", "title": "Reliability and convergent validity of a symbolic test for authoritarianism.", "content": "Reliability and convergent validity of a symbolic test for authoritarianism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195900"} {"pmid": "4195899", "title": "Development genetics of the lactate dehydrogenase isozymes of fish.", "content": "Development genetics of the lactate dehydrogenase isozymes of fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195899"} {"pmid": "4195901", "title": "Prevention of posttransfusion hepatitis by gamma-globulin. Preliminary report.", "content": "Prevention of posttransfusion hepatitis by gamma-globulin. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195901"} {"pmid": "4195904", "title": "Sheep, minks, savages and presenile dementia. The story of slow viruses.", "content": "Sheep, minks, savages and presenile dementia. The story of slow viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195904"} {"pmid": "4195902", "title": "Structures of schizophrenic forms of expression.", "content": "Structures of schizophrenic forms of expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195902"} {"pmid": "4195903", "title": "Typical findings in pathological grief.", "content": "Typical findings in pathological grief.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195903"} {"pmid": "4195906", "title": "Human secretory immunoglobulins. I. Salivary secretions from individuals with normal or low levels of serum immunoglobulins.", "content": "Human secretory immunoglobulins. I. Salivary secretions from individuals with normal or low levels of serum immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195906"} {"pmid": "4195907", "title": "Analysis of results of the 1969 comprehensive chemistry survey of the College of American Pathologists.", "content": "Analysis of results of the 1969 comprehensive chemistry survey of the College of American Pathologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195907"} {"pmid": "4195911", "title": "Invasion of cartilage by an experimental rat tumor.", "content": "Invasion of cartilage by an experimental rat tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195911"} {"pmid": "4195908", "title": "Low protein intake and response to Escherichia coli 055 infection in patas monkeys.", "content": "Low protein intake and response to Escherichia coli 055 infection in patas monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195908"} {"pmid": "4195912", "title": "Microspectrofluorometric comparison of acridine orange dye binding in meristematic and parenchymal nuclei of the orchid embryo.", "content": "Microspectrofluorometric comparison of acridine orange dye binding in meristematic and parenchymal nuclei of the orchid embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195912"} {"pmid": "4195909", "title": "Microscopic evaluation of the effects of some vital staining agents on growing bone in rabbits.", "content": "Microscopic evaluation of the effects of some vital staining agents on growing bone in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195909"} {"pmid": "4195910", "title": "A new virus in a spontaneous mammary tumor of a rhesus monkey.", "content": "A new virus in a spontaneous mammary tumor of a rhesus monkey. This study investigated the ultrastructure and development of virus particles detected in a spontaneous mammary tumor of an 8 year old rhesus monkey. During a 3-month period of tumor growth, several biopsies were performed. Thin section electron microscopy of the tumor tissue revealed 2 types of particles: 1) an intracytoplasmic, electron-dense, ring-shaped particle, and 2) an extracellular particle with an outer unit membrane and a central dense nucleoid. The intracytoplasmic development and virus maturation by a process of budding at the level of the cell membrane was reconstructed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195910"} {"pmid": "4195913", "title": "Histological staining properties of procion yellow M4RS.", "content": "Histological staining properties of procion yellow M4RS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195913"} {"pmid": "4195914", "title": "Chlorphenesin: a new inhibitor IgE-mediated histamine release.", "content": "Chlorphenesin: a new inhibitor IgE-mediated histamine release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195914"} {"pmid": "4195915", "title": "Cytoplasmic inclusions and nuclear changes in cells infected with influenza-B viruses.", "content": "Cytoplasmic inclusions and nuclear changes in cells infected with influenza-B viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195915"} {"pmid": "4195917", "title": "The experimental infection of calves with bacteriaemia-producing strains of Escherichia coli: the influence of colostrum.", "content": "The experimental infection of calves with bacteriaemia-producing strains of Escherichia coli: the influence of colostrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195917"} {"pmid": "4195916", "title": "The laboratory diagnosis of vaginal infections caused by Trichomonas and Candida (Monilia) species.", "content": "The laboratory diagnosis of vaginal infections caused by Trichomonas and Candida (Monilia) species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195916"} {"pmid": "4195918", "title": "The pathogenesis of Sendai virus infection in the mouse lung.", "content": "The pathogenesis of Sendai virus infection in the mouse lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195918"} {"pmid": "4195920", "title": "Substructure in negatively stained flagella of Pteridium spermatozoids.", "content": "Substructure in negatively stained flagella of Pteridium spermatozoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195920"} {"pmid": "4195919", "title": "Fine structure of early cartilage calcification.", "content": "Fine structure of early cartilage calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195919"} {"pmid": "4195921", "title": "Structural differences between old and young negatively stained red cell membranes.", "content": "Structural differences between old and young negatively stained red cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195921"} {"pmid": "4195922", "title": "A study of the anatomy of the prostate, prostatic urethra and the urinary sphincter system.", "content": "A study of the anatomy of the prostate, prostatic urethra and the urinary sphincter system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195922"} {"pmid": "4195924", "title": "Lethal freezing temperatures of the surgical capsule and cryosurgery of the prostate.", "content": "Lethal freezing temperatures of the surgical capsule and cryosurgery of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195924"} {"pmid": "4195923", "title": "The transurethral resection reaction secondary to intraperitoneal extravasation of irrigating solution.", "content": "The transurethral resection reaction secondary to intraperitoneal extravasation of irrigating solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195923"} {"pmid": "4195925", "title": "Cellular compartmentalization of herpesvirus antigens during viral replication.", "content": "Cellular compartmentalization of herpesvirus antigens during viral replication. HEp-2 cells infected with herpes simplex virus develop five distinct immunofluorescent elements. Three (small nuclear granules, large nuclear granules, and an amorphous mass filling the nucleus) contain antigens which react with a rabbit serum prepared against boiled infected cell debris. A labeled pool of human antibody revealed antigens making up cytoplasmic granules and those responsible for a diffuse cytoplasmic fluorescence. All five immunofluorescent elements are demonstrable with a rabbit serum prepared against unheated infected cell debris. Viral antigens are segregated in the nucleus or in the cytoplasm; within the limits of detection, each antigen accumulates in one compartment only. The antigens responsible for the diffuse cytoplasmic fluorescence and for the amorphous nuclear mass are synthesized early in infection; they are formed in arginine-deprived cells and exist in a form which does not sediment on centrifugation at 79,000 x g for 2 hr. The antigens comprising the nuclear and cytoplasmic granules arise relatively late in infection; they are not formed in arginine-deprived cells, and they are readily sedimented on centrifugation at 79,000 x g for 2 hr. Heating (60 C for 2 hr) confers on one or more cytoplasmic viral antigens a new specificity; the altered antigens are demonstrable with labeled rabbit anti-boiled infected cell serum which normally does not combine with cytoplasmic antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195925"} {"pmid": "4195927", "title": "A histochemical and ultrastructural study of intimal bodies of horse arterioles.", "content": "A histochemical and ultrastructural study of intimal bodies of horse arterioles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195927"} {"pmid": "4195928", "title": "Levitation in treatment of large-area burns.", "content": "Levitation in treatment of large-area burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195928"} {"pmid": "4195926", "title": "Reovirus-directed ribonucleic acid synthesis in infected L cells.", "content": "Reovirus-directed ribonucleic acid synthesis in infected L cells. Reovirus replication in L-929 mouse fibroblasts was unaffected by 0.5 mug of actinomycin per ml, a concentration which inhibited cell ribonucleic acid (RNA) synthesis by more than 90%. Under these conditions of selective inhibition, the formation of both single-stranded and double-stranded virus-specific RNA was detected beginning at 6 hr after infection. The purified double-stranded RNA was similar in size and base composition to virus RNA and presumably was incorporated into mature virus. The single-stranded RNA formed ribonuclease-resistant duplexes when annealed with denatured virus RNA but did not self-anneal, thus indicating that it includes copies of only one strand of the duplex. The single-stranded RNA was polyribosome-associated and may function as the virus messenger RNA. Production of both types of virus-induced RNA required protein synthesis 6 to 9 hr after infection. At later times in the infectious cycle, only double-stranded RNA synthesis was dependent on continued protein formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195926"} {"pmid": "4195929", "title": "Long-term results with iodine-125 treatment for toxic diffuse goitre.", "content": "Long-term results with iodine-125 treatment for toxic diffuse goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195929"} {"pmid": "4195931", "title": "Long-term continuous intracranial-pressure monitoring by means of a modified subdural pressure transducer.", "content": "Long-term continuous intracranial-pressure monitoring by means of a modified subdural pressure transducer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195931"} {"pmid": "4195930", "title": "Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy.", "content": "Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195930"} {"pmid": "4195932", "title": "Rapid diagnosis of influenza by immunofluorescent techniques.", "content": "Rapid diagnosis of influenza by immunofluorescent techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195932"} {"pmid": "4195933", "title": "Lead and delta-aminolaevulinic acid dehydratase levels in mentally retarded children and in lead-poisoned suckling rats.", "content": "Lead and delta-aminolaevulinic acid dehydratase levels in mentally retarded children and in lead-poisoned suckling rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195933"} {"pmid": "4195934", "title": "Natural gas: friend or foe?", "content": "Natural gas: friend or foe?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195934"} {"pmid": "4195936", "title": "Occupational health: the next move?", "content": "Occupational health: the next move?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195936"} {"pmid": "4195935", "title": "Treatment of chronic hypoxaemia.", "content": "Treatment of chronic hypoxaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195935"} {"pmid": "4195937", "title": "Experiments on living animals.", "content": "Experiments on living animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195937"} {"pmid": "4195938", "title": "Impasse.", "content": "Impasse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195938"} {"pmid": "4195939", "title": "Cytological examination of endometrium.", "content": "Cytological examination of endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195939"} {"pmid": "4195940", "title": "Printing of The Lancet.", "content": "Printing of The Lancet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195940"} {"pmid": "4195941", "title": "After the earthquake.", "content": "After the earthquake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195941"} {"pmid": "4195942", "title": "Regional service for acute and chronic dialysis of children.", "content": "Regional service for acute and chronic dialysis of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195942"} {"pmid": "4195944", "title": "Ten years of boarding-out in Somerset.", "content": "Ten years of boarding-out in Somerset.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195944"} {"pmid": "4195943", "title": "Immunosurveillance and cancer.", "content": "Immunosurveillance and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195943"} {"pmid": "4195945", "title": "Increasing frequency of a syndrome of multiple osseous defects?", "content": "Increasing frequency of a syndrome of multiple osseous defects?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195945"} {"pmid": "4195946", "title": "Therapeutic abortion by local administration of prostaglandin.", "content": "Therapeutic abortion by local administration of prostaglandin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195946"} {"pmid": "4195947", "title": "Social work in general practice.", "content": "Social work in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195947"} {"pmid": "4195948", "title": "S.H. antigen and chronic liver disease.", "content": "S.H. antigen and chronic liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195948"} {"pmid": "4195949", "title": "Liver disease in ulcerative colitis.", "content": "Liver disease in ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195949"} {"pmid": "4195950", "title": "Muscle relaxation during anaesthesia.", "content": "Muscle relaxation during anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195950"} {"pmid": "4195951", "title": "Caesarean section under local anaesthesia.", "content": "Caesarean section under local anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195951"} {"pmid": "4195952", "title": "Fatal massive liver necrosis after repeated methoxyflurane anaesthesia.", "content": "Fatal massive liver necrosis after repeated methoxyflurane anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195952"} {"pmid": "4195953", "title": "Severe myositis during recovery from influenza.", "content": "Severe myositis during recovery from influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195953"} {"pmid": "4195954", "title": "Treatment of Parkinsonism with L-dopa and amantadine.", "content": "Treatment of Parkinsonism with L-dopa and amantadine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195954"} {"pmid": "4195955", "title": "Mental symptoms in parkinsonian patients treated with L-dopa.", "content": "Mental symptoms in parkinsonian patients treated with L-dopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195955"} {"pmid": "4195956", "title": "L-asparaginase and pancreatitis.", "content": "L-asparaginase and pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195956"} {"pmid": "4195957", "title": "In-vitro cytotoxicity of L-asparaginase on rodent and human neoplastic cells.", "content": "In-vitro cytotoxicity of L-asparaginase on rodent and human neoplastic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195957"} {"pmid": "4195958", "title": "Detection of bacteriuria.", "content": "Detection of bacteriuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195958"} {"pmid": "4195959", "title": "Blood-groups, cholesterol, and myocardial infarction.", "content": "Blood-groups, cholesterol, and myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195959"} {"pmid": "4195960", "title": "Effect of dietary fats and carbohydrates on serum-lipids in the rat.", "content": "Effect of dietary fats and carbohydrates on serum-lipids in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195960"} {"pmid": "4195961", "title": "Amitriptyline and cardiac disease.", "content": "Amitriptyline and cardiac disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195961"} {"pmid": "4195962", "title": "Tropical sprue in the Caribbean.", "content": "Tropical sprue in the Caribbean.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195962"} {"pmid": "4195963", "title": "Chronic diarrhoea and marasmus.", "content": "Chronic diarrhoea and marasmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195963"} {"pmid": "4195964", "title": "Lymphocyte transformation in coeliac disease.", "content": "Lymphocyte transformation in coeliac disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195964"} {"pmid": "4195965", "title": "Lactose intolerance following measles.", "content": "Lactose intolerance following measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195965"} {"pmid": "4195966", "title": "Carrageenan and the human gut.", "content": "Carrageenan and the human gut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195966"} {"pmid": "4195968", "title": "The at-risk register.", "content": "The at-risk register.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195968"} {"pmid": "4195967", "title": "Glomerular lesions in acute pancreatitis.", "content": "Glomerular lesions in acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195967"} {"pmid": "4195969", "title": "Recurrence risks for cleft lip and cleft palate in British Columbia Indians.", "content": "Recurrence risks for cleft lip and cleft palate in British Columbia Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195969"} {"pmid": "4195971", "title": "Medical care in the United States.", "content": "Medical care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195971"} {"pmid": "4195970", "title": "The handless and footless families of Brazil.", "content": "The handless and footless families of Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195970"} {"pmid": "4195972", "title": "Long-term remission in acute leukaemia.", "content": "Long-term remission in acute leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195972"} {"pmid": "4195973", "title": "Toxicity of dithiothreitol.", "content": "Toxicity of dithiothreitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195973"} {"pmid": "4195974", "title": "Adam Patrick.", "content": "Adam Patrick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195974"} {"pmid": "4195975", "title": "Hypothalamo-pituitary-adrenal function in asthmatic patients receiving long-term corticosteroid therapy.", "content": "Hypothalamo-pituitary-adrenal function in asthmatic patients receiving long-term corticosteroid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195975"} {"pmid": "4195976", "title": "Acetone in diabetic ketoacidosis.", "content": "Acetone in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195976"} {"pmid": "4195977", "title": "Small blood-vessels in migraine.", "content": "Small blood-vessels in migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195977"} {"pmid": "4195978", "title": "Delayed psychosis due to L.S.D.", "content": "Delayed psychosis due to L.S.D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195978"} {"pmid": "4195979", "title": "Familial sideroblastic anaemia: problem of Xg and X chromosome inactivation.", "content": "Familial sideroblastic anaemia: problem of Xg and X chromosome inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195979"} {"pmid": "4195980", "title": "Serum gamma-glutamyl transpeptidase as a diagnostic aid.", "content": "Serum gamma-glutamyl transpeptidase as a diagnostic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195980"} {"pmid": "4195981", "title": "Heparin treatment for post-partum renal failure with microangiopathic haemolytic anaemia.", "content": "Heparin treatment for post-partum renal failure with microangiopathic haemolytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195981"} {"pmid": "4195982", "title": "Role of myocardium in the modern epidemic of ischaemic heart-disease.", "content": "Role of myocardium in the modern epidemic of ischaemic heart-disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195982"} {"pmid": "4195983", "title": "Combined treatment of leukaemias and reticuloses.", "content": "Combined treatment of leukaemias and reticuloses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195983"} {"pmid": "4195984", "title": "Lung cancer in haematite miners.", "content": "Lung cancer in haematite miners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195984"} {"pmid": "4195985", "title": "Like gout.", "content": "Like gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195985"} {"pmid": "4195986", "title": "Amantidine and influenza in general practice.", "content": "Amantidine and influenza in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195986"} {"pmid": "4195987", "title": "The McMaster medical school at Hamilton, Ontario.", "content": "The McMaster medical school at Hamilton, Ontario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195987"} {"pmid": "4195988", "title": "Trimethylaminuria: the fish-odour syndrome.", "content": "Trimethylaminuria: the fish-odour syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195988"} {"pmid": "4195989", "title": "Burkitt lymphoma and malaria.", "content": "Burkitt lymphoma and malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195989"} {"pmid": "4195990", "title": "E.B. virus and lymphomas.", "content": "E.B. virus and lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195990"} {"pmid": "4195991", "title": "Leucocyte phenotypes in Hodgkin's disease.", "content": "Leucocyte phenotypes in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195991"} {"pmid": "4195992", "title": "Human lymphoid cell lines: potential hazards to laboratory workers.", "content": "Human lymphoid cell lines: potential hazards to laboratory workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195992"} {"pmid": "4195993", "title": "Intranuclear aggregates in the liver of a patient with serum hepatitis.", "content": "Intranuclear aggregates in the liver of a patient with serum hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195993"} {"pmid": "4195994", "title": "Iron therapy for haemodialysis patients.", "content": "Iron therapy for haemodialysis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195994"} {"pmid": "4195995", "title": "Acute myeloid leukaemia after treatment with cytostatic agents.", "content": "Acute myeloid leukaemia after treatment with cytostatic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195995"} {"pmid": "4195997", "title": "Coagulation abnormalities in generalised herpes-simplex infection of newborn.", "content": "Coagulation abnormalities in generalised herpes-simplex infection of newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195997"} {"pmid": "4195996", "title": "Triethylene tetramine dihydrochloride in Wilson's disease.", "content": "Triethylene tetramine dihydrochloride in Wilson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195996"} {"pmid": "4195998", "title": "Sea-blue-histiocyte syndrome.", "content": "Sea-blue-histiocyte syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195998"} {"pmid": "4195999", "title": "L-tryptophan in depression.", "content": "L-tryptophan in depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4195999"} {"pmid": "4196000", "title": "Contaminated antiseptic solutions.", "content": "Contaminated antiseptic solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196000"} {"pmid": "4196001", "title": "The choroid plexus in African sleeping-sickness.", "content": "The choroid plexus in African sleeping-sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196001"} {"pmid": "4196002", "title": "Beta-blocking effect of practolol in asthmatics.", "content": "Beta-blocking effect of practolol in asthmatics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196002"} {"pmid": "4196003", "title": "Perinatal mortality.", "content": "Perinatal mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196003"} {"pmid": "4196004", "title": "Plasticisers from P.V.C.", "content": "Plasticisers from P.V.C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196004"} {"pmid": "4196005", "title": "Tetraploidy in cells cultured from amniotic fluid.", "content": "Tetraploidy in cells cultured from amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196005"} {"pmid": "4196006", "title": "Sympathomimetic agents and serum-lipid levels.", "content": "Sympathomimetic agents and serum-lipid levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196006"} {"pmid": "4196007", "title": "Intrauterine administration of prostaglandins.", "content": "Intrauterine administration of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196007"} {"pmid": "4196008", "title": "Lactic acidosis in diabetic coma.", "content": "Lactic acidosis in diabetic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196008"} {"pmid": "4196009", "title": "Solutions for kidney storage.", "content": "Solutions for kidney storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196009"} {"pmid": "4196010", "title": "Amyloidosis, Alzheimer's disease, and ageing.", "content": "Amyloidosis, Alzheimer's disease, and ageing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196010"} {"pmid": "4196011", "title": "Phenformin and blood-urea.", "content": "Phenformin and blood-urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196011"} {"pmid": "4196012", "title": "Rubella and rheumatoid arthritis.", "content": "Rubella and rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196012"} {"pmid": "4196013", "title": "Trisomy 18.", "content": "Trisomy 18.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196013"} {"pmid": "4196014", "title": "Epileptic death due to suffocation during sleep.", "content": "Epileptic death due to suffocation during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196014"} {"pmid": "4196015", "title": "Treatment of nephroblastoma and neuroblastoma: M.R.C. trials.", "content": "Treatment of nephroblastoma and neuroblastoma: M.R.C. trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196015"} {"pmid": "4196017", "title": "Leg-vein thrombosis following myocardial infarction.", "content": "Leg-vein thrombosis following myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196017"} {"pmid": "4196016", "title": "Klebsiella in faecal flora of renal-transplant patients.", "content": "Klebsiella in faecal flora of renal-transplant patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196016"} {"pmid": "4196018", "title": "Seasonal incidence and mortality of ischaemic heart-disease.", "content": "Seasonal incidence and mortality of ischaemic heart-disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196018"} {"pmid": "4196020", "title": "Sciatica caused by sacral-nerve-root cysts.", "content": "Sciatica caused by sacral-nerve-root cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196020"} {"pmid": "4196019", "title": "Metabolic findings in hyperosmolar, non-ketotic diabetic stupor.", "content": "Metabolic findings in hyperosmolar, non-ketotic diabetic stupor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196019"} {"pmid": "4196022", "title": "Bacteria in faeces and food.", "content": "Bacteria in faeces and food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196022"} {"pmid": "4196021", "title": "Fundamental physiological role of parathyroid hormone in acid-base homoeostasis.", "content": "Fundamental physiological role of parathyroid hormone in acid-base homoeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196021"} {"pmid": "4196023", "title": "Thyroid-function tests.", "content": "Thyroid-function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196023"} {"pmid": "4196024", "title": "Making plans.", "content": "Making plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196024"} {"pmid": "4196025", "title": "Delayed overture.", "content": "Delayed overture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196025"} {"pmid": "4196026", "title": "Safer roads?", "content": "Safer roads?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196026"} {"pmid": "4196027", "title": "The last of the sixties.", "content": "The last of the sixties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196027"} {"pmid": "4196028", "title": "Apathetic thyrotoxicosis.", "content": "Apathetic thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196028"} {"pmid": "4196029", "title": "More than enough.", "content": "More than enough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196029"} {"pmid": "4196030", "title": "Tasmania's medical school.", "content": "Tasmania's medical school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196030"} {"pmid": "4196031", "title": "The relief operation in former Biafra.", "content": "The relief operation in former Biafra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196031"} {"pmid": "4196032", "title": "Audiovisual aids in medical schools.", "content": "Audiovisual aids in medical schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196032"} {"pmid": "4196033", "title": "Experiments on living animals.", "content": "Experiments on living animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196033"} {"pmid": "4196034", "title": "Blood-groups and hypopharyngeal cancer.", "content": "Blood-groups and hypopharyngeal cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196034"} {"pmid": "4196035", "title": "Immune responses in malaria.", "content": "Immune responses in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196035"} {"pmid": "4196036", "title": "Social work in general practice.", "content": "Social work in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196036"} {"pmid": "4196037", "title": "Social work in general practice.", "content": "Social work in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196037"} {"pmid": "4196038", "title": "Social work in general practice.", "content": "Social work in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196038"} {"pmid": "4196039", "title": "Use of the casualty department.", "content": "Use of the casualty department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196039"} {"pmid": "4196040", "title": "Emergency call service.", "content": "Emergency call service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196040"} {"pmid": "4196041", "title": "At-risk register.", "content": "At-risk register.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196041"} {"pmid": "4196043", "title": "Epidemiology of gallstone disease.", "content": "Epidemiology of gallstone disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196043"} {"pmid": "4196042", "title": "Mortality in urinary schistosomiasis.", "content": "Mortality in urinary schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196042"} {"pmid": "4196044", "title": "Spontaneous intracerebral haematoma in a patient undergoing haemodialysis.", "content": "Spontaneous intracerebral haematoma in a patient undergoing haemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196044"} {"pmid": "4196045", "title": "Dilution and transfusion.", "content": "Dilution and transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196045"} {"pmid": "4196046", "title": "Coordinated care of the child with spina bifida.", "content": "Coordinated care of the child with spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196046"} {"pmid": "4196047", "title": "Virus-like particles in infectious hepatitis.", "content": "Virus-like particles in infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196047"} {"pmid": "4196048", "title": "Au antigen in liver cirrhosis.", "content": "Au antigen in liver cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196048"} {"pmid": "4196050", "title": "Aplastic anaemia and infectious hepatitis.", "content": "Aplastic anaemia and infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196050"} {"pmid": "4196049", "title": "Infectious hepatitis and Down's syndrome.", "content": "Infectious hepatitis and Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196049"} {"pmid": "4196051", "title": "H.A.A. at the barber's?", "content": "H.A.A. at the barber's?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196051"} {"pmid": "4196052", "title": "Tropical sprue in Africa.", "content": "Tropical sprue in Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196052"} {"pmid": "4196053", "title": "Intestinal transport of fructose.", "content": "Intestinal transport of fructose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196053"} {"pmid": "4196054", "title": "Carrageenan: effects in animals.", "content": "Carrageenan: effects in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196054"} {"pmid": "4196055", "title": "Serum gamma-glutamyl transpeptidase as a diagnostic aid.", "content": "Serum gamma-glutamyl transpeptidase as a diagnostic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196055"} {"pmid": "4196056", "title": "Preservation of serum-acid-phosphatase.", "content": "Preservation of serum-acid-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196056"} {"pmid": "4196057", "title": "Junior hospital staff in training.", "content": "Junior hospital staff in training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196057"} {"pmid": "4196058", "title": "Effect of propranolol on serum-thyroxine.", "content": "Effect of propranolol on serum-thyroxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196058"} {"pmid": "4196059", "title": "Lay hypochondria.", "content": "Lay hypochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196059"} {"pmid": "4196060", "title": "Effect of allopurinol on pyrimidine metabolism in the Lesch-Nyhan syndrome.", "content": "Effect of allopurinol on pyrimidine metabolism in the Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196060"} {"pmid": "4196062", "title": "Abnormal pharmacokinetics of phenytoin in a patient with uraemia.", "content": "Abnormal pharmacokinetics of phenytoin in a patient with uraemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196062"} {"pmid": "4196061", "title": "Delayed psychosis due to L.S.D.", "content": "Delayed psychosis due to L.S.D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196061"} {"pmid": "4196063", "title": "Sex-chromatin and menstrual cycle.", "content": "Sex-chromatin and menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196063"} {"pmid": "4196064", "title": "Small blood-vessels in migraine.", "content": "Small blood-vessels in migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196064"} {"pmid": "4196065", "title": "Register of interpreters.", "content": "Register of interpreters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196065"} {"pmid": "4196066", "title": "Rapid axonal transport of sulfated mucopolysaccharide proteins.", "content": "Rapid axonal transport of sulfated mucopolysaccharide proteins. When sulfur-35-labeled sodium sulfate is injected intraocularly in the goldfish, labeled sulfated mucopolysaccharides rapidly appear in the contra-lateral optic tectum of the brain, demonstrating the axonal flow of sulfated mucopolysaccharides. The transport rate is the same as that observed for proteins labeled after intraocular injection of tritiated proline. Treatment of the sulfur-35-labeled material with precipitants and enzymes reveals the presence of substances with properties similar to those of heparan sulfate (the major component) and chondroitin sulfate. Dermatan sulfate was not detected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196066"} {"pmid": "4196067", "title": "Radioresistance of cooperative function of carrier-specific lymphocytes in antihapten antibody responses.", "content": "Radioresistance of cooperative function of carrier-specific lymphocytes in antihapten antibody responses. Transfer of lymphoid cells from strain-2 guinea pigs immunized to bovine gamma globulin into syngeneic recipients immunized with dinitrophenyl ovalbumin markedly enhances the secondary antidinitrophenyl response of the recipient to challenge with dinitrophenyl-bovine gamma globulin. This function of the carrier bovine gamma globulin-specific cells is resistant to irradiation with up to 5000 rads, although the capacity of the irradiated cell population to transfer immunologic memory for bovine gamma globulins or to be stimulated by antigen to synthesize DNA in vitro is abolished by this treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196067"} {"pmid": "4196068", "title": "Tumors of the skin. Considerations on total excision.", "content": "Tumors of the skin. Considerations on total excision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196068"} {"pmid": "4196069", "title": "Benzene hexachloride poisonong.", "content": "Benzene hexachloride poisonong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196069"} {"pmid": "4196071", "title": "Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. II. Negative staining.", "content": "Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. II. Negative staining.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196071"} {"pmid": "4196072", "title": "Study on histologic changes of periodontal membrane incident to experimental tooth movement.", "content": "Study on histologic changes of periodontal membrane incident to experimental tooth movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196072"} {"pmid": "4196074", "title": "Automation of a quantitative immunochemical microanalysis of human serum transferrin: a model system.", "content": "Automation of a quantitative immunochemical microanalysis of human serum transferrin: a model system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196074"} {"pmid": "4196075", "title": "A simple way to index, file and retrieve slides.", "content": "A simple way to index, file and retrieve slides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196075"} {"pmid": "4196070", "title": "Current concepts of the pathogenesis and management of asthma.", "content": "Current concepts of the pathogenesis and management of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196070"} {"pmid": "4196076", "title": "Rubella vaccine.", "content": "Rubella vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196076"} {"pmid": "4196073", "title": "Induction of T antigen, new surface antigen, and transplantation immunity by a nontumorigenic variant of type 3 bovine adenovirus.", "content": "Induction of T antigen, new surface antigen, and transplantation immunity by a nontumorigenic variant of type 3 bovine adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196073"} {"pmid": "4196077", "title": "Slides add emphasis to food service training program.", "content": "Slides add emphasis to food service training program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196077"} {"pmid": "4196078", "title": "Studies on the morphopoiesis of the head of bacteriophage T-even. 8. Multilayered polyheads.", "content": "Studies on the morphopoiesis of the head of bacteriophage T-even. 8. Multilayered polyheads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196078"} {"pmid": "4196079", "title": "Electron microscope observations on actomyosin and actin preparations from Physarum polycephalum, and on their interaction with heavy meromyosin subfragment I from muscle myosin.", "content": "Electron microscope observations on actomyosin and actin preparations from Physarum polycephalum, and on their interaction with heavy meromyosin subfragment I from muscle myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196079"} {"pmid": "4196083", "title": "Preservation of intercellular substances by the cationic dye alcian blue in preparative procedures for electron microscopy.", "content": "Preservation of intercellular substances by the cationic dye alcian blue in preparative procedures for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196083"} {"pmid": "4196086", "title": "The drops of life: fluids and electrolytes.", "content": "The drops of life: fluids and electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196086"} {"pmid": "4196087", "title": "The drops of life. I.V. therapy as a nursing responsibility.", "content": "The drops of life. I.V. therapy as a nursing responsibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196087"} {"pmid": "4196089", "title": "Good-by, Mary.", "content": "Good-by, Mary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196089"} {"pmid": "4196088", "title": "Hypervolaemia in status asthmaticus.", "content": "Hypervolaemia in status asthmaticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196088"} {"pmid": "4196090", "title": "RN reports from Chicago.", "content": "RN reports from Chicago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196090"} {"pmid": "4196091", "title": "Effect of L-dopa on seborrhoea of parkinsonism.", "content": "Effect of L-dopa on seborrhoea of parkinsonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196091"} {"pmid": "4196093", "title": "Death is a family matter.", "content": "Death is a family matter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196093"} {"pmid": "4196092", "title": "Diagnosing thyroid carcinoma.", "content": "Diagnosing thyroid carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196092"} {"pmid": "4196094", "title": "Abortion: a stormy subject.", "content": "Abortion: a stormy subject.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196094"} {"pmid": "4196096", "title": "A multi-media curricular approachin the making.", "content": "A multi-media curricular approachin the making.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196096"} {"pmid": "4196097", "title": "Carcinogenic natural products.", "content": "Carcinogenic natural products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196097"} {"pmid": "4196098", "title": "Irradiated humans: microbial flora, immunoglobulins, complement (C'3), transferrin, agglutinins, and bacteriocidins.", "content": "Irradiated humans: microbial flora, immunoglobulins, complement (C'3), transferrin, agglutinins, and bacteriocidins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196098"} {"pmid": "4196103", "title": "\"Plotting\" the basic curriculum.", "content": "\"Plotting\" the basic curriculum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196103"} {"pmid": "4196104", "title": "The OR nurse in the patient care circuit.", "content": "The OR nurse in the patient care circuit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196104"} {"pmid": "4196105", "title": "Editorial: the challenge and the future in nursing.", "content": "Editorial: the challenge and the future in nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196105"} {"pmid": "4196106", "title": "Anesthesia for the aged.", "content": "Anesthesia for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196106"} {"pmid": "4196107", "title": "Change--can nursing make it?", "content": "Change--can nursing make it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196107"} {"pmid": "4196109", "title": "An historical review of \"Die Symbolik des Traumes\". (Chapters I-VI).", "content": "An historical review of \"Die Symbolik des Traumes\". (Chapters I-VI).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196109"} {"pmid": "4196111", "title": "Idiopathic infantile arterial calcification--a misnomer?", "content": "Idiopathic infantile arterial calcification--a misnomer?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196111"} {"pmid": "4196114", "title": "Selective zinc iodide-osmium tetroxide impregnation of synaptoid vesicles in the rat neurohyophysis.", "content": "Selective zinc iodide-osmium tetroxide impregnation of synaptoid vesicles in the rat neurohyophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196114"} {"pmid": "4196115", "title": "Thyroid function tests: a review.", "content": "Thyroid function tests: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196115"} {"pmid": "4196119", "title": "Increased glycogen accumulation in normal stimulated lymphocytes in vitro by modifying the conditions of cultivation.", "content": "Increased glycogen accumulation in normal stimulated lymphocytes in vitro by modifying the conditions of cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196119"} {"pmid": "4196120", "title": "A comparative cytochemical study of leukocytes of some animal species.", "content": "A comparative cytochemical study of leukocytes of some animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196120"} {"pmid": "4196121", "title": "Bone marrow and spleen interrelation in local irradiation: data of cytometry and Fe59 incorporation.", "content": "Bone marrow and spleen interrelation in local irradiation: data of cytometry and Fe59 incorporation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196121"} {"pmid": "4196123", "title": "The acid-base conditions of ACD blood during storage.", "content": "The acid-base conditions of ACD blood during storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196123"} {"pmid": "4196124", "title": "Naturally occurring anti-CW antibody and the frequency of the CW antigen in blood donors of the county Pest.", "content": "Naturally occurring anti-CW antibody and the frequency of the CW antigen in blood donors of the county Pest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196124"} {"pmid": "4196125", "title": "Effects of deleterious oral habits on the dento-facial complex.", "content": "Effects of deleterious oral habits on the dento-facial complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196125"} {"pmid": "4196126", "title": "Clinical and metabolic study in hypothyroidism.", "content": "Clinical and metabolic study in hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196126"} {"pmid": "4196127", "title": "Modern management of the Rh incompatible pregnancy.", "content": "Modern management of the Rh incompatible pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196127"} {"pmid": "4196128", "title": "Seminar on care of the newborn. IV. Newborn hematologic problems.", "content": "Seminar on care of the newborn. IV. Newborn hematologic problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196128"} {"pmid": "4196129", "title": "The quantitation of nerve biopsy findings.", "content": "The quantitation of nerve biopsy findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196129"} {"pmid": "4196130", "title": "Cytology of the tonsils.", "content": "Cytology of the tonsils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196130"} {"pmid": "4196133", "title": "The effect of experimental constriction on the structure of the sciatic nerve.", "content": "The effect of experimental constriction on the structure of the sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196133"} {"pmid": "4196134", "title": "Balloon atrial septostomy in complete transposition of the great vessels.", "content": "Balloon atrial septostomy in complete transposition of the great vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196134"} {"pmid": "4196139", "title": "Rhabdomyosarcoma of the middle cranial fossa.", "content": "Rhabdomyosarcoma of the middle cranial fossa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196139"} {"pmid": "4196132", "title": "Technical aids in surgery. The palliative operation for obstructive jaundice due to carcinoma of the pancreas.", "content": "Technical aids in surgery. The palliative operation for obstructive jaundice due to carcinoma of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196132"} {"pmid": "4196140", "title": "Evaluation of EDTA as the chelator in the biuret reagent.", "content": "Evaluation of EDTA as the chelator in the biuret reagent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196140"} {"pmid": "4196142", "title": "Clinical and immunological studies following immunotherapy with aqueous and alum precipitated reagweed fraction A.", "content": "Clinical and immunological studies following immunotherapy with aqueous and alum precipitated reagweed fraction A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196142"} {"pmid": "4196136", "title": "The decision making process in cancer patient care.", "content": "The decision making process in cancer patient care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196136"} {"pmid": "4196143", "title": "IgE levels, antibodies against smooth muscle and eosinophilia in asthmatic patients and normal controls.", "content": "IgE levels, antibodies against smooth muscle and eosinophilia in asthmatic patients and normal controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196143"} {"pmid": "4196144", "title": "IgE levels in external secretions.", "content": "IgE levels in external secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196144"} {"pmid": "4196138", "title": "Classes in oncology: George Nicholas Papanicolaou's new cancer diagnosis presented at the Third Race Betterment Conference, Battle Creek, Michigan, January 2-6, 1928, and published in the Proceedings of the Conference.", "content": "Classes in oncology: George Nicholas Papanicolaou's new cancer diagnosis presented at the Third Race Betterment Conference, Battle Creek, Michigan, January 2-6, 1928, and published in the Proceedings of the Conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196138"} {"pmid": "4196145", "title": "Membrane antigens of human colonic carcinoma and non-tumoral colonic mucosa: results obtained with a new isolation method.", "content": "Membrane antigens of human colonic carcinoma and non-tumoral colonic mucosa: results obtained with a new isolation method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196145"} {"pmid": "4196146", "title": "The therapeutic dietitian's role in the Alimentation Group.", "content": "The therapeutic dietitian's role in the Alimentation Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196146"} {"pmid": "4196147", "title": "Relationship between a metabolic rhythm and emergence rhythm in Drosophila melanogaster.", "content": "Relationship between a metabolic rhythm and emergence rhythm in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196147"} {"pmid": "4196148", "title": "Physiological factors in the courtship processing of Drosophila melanogaster.", "content": "Physiological factors in the courtship processing of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196148"} {"pmid": "4196149", "title": "Morphogenetic effects of juvenile hormone and juvenile hormone mimics on adult development of Drosophila.", "content": "Morphogenetic effects of juvenile hormone and juvenile hormone mimics on adult development of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196149"} {"pmid": "4196150", "title": "Effects of protein-calorie malnutrition on drug metabolism in rat liver microsomes.", "content": "Effects of protein-calorie malnutrition on drug metabolism in rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196150"} {"pmid": "4196151", "title": "The separate effects of protein and calorie malnutrition on the development and growth of rat bones and teeth.", "content": "The separate effects of protein and calorie malnutrition on the development and growth of rat bones and teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196151"} {"pmid": "4196152", "title": "Quantitative comparison of biological dressings.", "content": "Quantitative comparison of biological dressings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196152"} {"pmid": "4196153", "title": "Carotid perfusion hypothermia for brain surgery using cardiac arrest without bypass.", "content": "Carotid perfusion hypothermia for brain surgery using cardiac arrest without bypass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196153"} {"pmid": "4196137", "title": "George Nicholas Papanicolaou (1883-1962).", "content": "George Nicholas Papanicolaou (1883-1962).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196137"} {"pmid": "4196154", "title": "Neurologic disorders following live measles-virus vaccination.", "content": "Neurologic disorders following live measles-virus vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196154"} {"pmid": "4196155", "title": "Professional standards review organizations. Analysis of their development and implementation based on a preliminary review of the Hospital Admission and Surveillance Program in Illinois.", "content": "Professional standards review organizations. Analysis of their development and implementation based on a preliminary review of the Hospital Admission and Surveillance Program in Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196155"} {"pmid": "4196164", "title": "Clinical and physiopathological considerations on the hyperosmolar states with or without ketoacidosis.", "content": "Clinical and physiopathological considerations on the hyperosmolar states with or without ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196164"} {"pmid": "4196165", "title": "Whole body counter studies of iron absorption in patients with subtotal gastrectomy.", "content": "Whole body counter studies of iron absorption in patients with subtotal gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196165"} {"pmid": "4196166", "title": "The use of a nonabsorbable indicator ( 51 CrCl 3 ) method for measuring 14 C-labelled fatty-acid absorption in the intestine.", "content": "The use of a nonabsorbable indicator ( 51 CrCl 3 ) method for measuring 14 C-labelled fatty-acid absorption in the intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196166"} {"pmid": "4196167", "title": "Lower pH limit for the existence of blue-green algae: evolutionary and ecological implications.", "content": "Lower pH limit for the existence of blue-green algae: evolutionary and ecological implications. Observations on a wide variety of acidic environments, both natural and man-made, reveal that blue-green algae (Cyanophyta) are completely absent from habitats in which the pH is less than 4 or 5, whereas eukaryotic algae flourish. By using enrichment cultures with inocula from habitats of various pH values, the absence of blue-green algae at low pH was confirmed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196167"} {"pmid": "4196168", "title": "Sexual differentiation of pituitary function: apparent difference bewteen primates and rodents.", "content": "Sexual differentiation of pituitary function: apparent difference bewteen primates and rodents. Surges in luteinizing hormone secretion resembling those which occur spontaneously during the menstrual cycle were induced by acute elevations in circulating estrogen concentrations in both male and female rhesus monkeys gonadectomized in adulthood. These experiments demonstrate that in primates, in contrast to rodents, exposure of the hypothalamohypophyseal unit to androgens throughout fetal and postnatal development does not prevent the differentiation of the control system that governs cyclic gonadotropin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196168"} {"pmid": "4196169", "title": "Sexual behavior in rhesus monkeys after vasectomy.", "content": "Sexual behavior in rhesus monkeys after vasectomy. Vasectomy had no statistically significant effect on the sexual behavior of vigorous adult rhesus monkeys. Of two groups of males matched for level of sexual performance, one was vasectomized and the other underwent sham vasectomy. In sex tests administered within the month after surgery, the groups showed no difference (P .05) in rate of mounting, intromission, or ejaculation, or in any other measure of sexual or sex-related behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196169"} {"pmid": "4196171", "title": "Motor cortex reflexes associated with learned movement.", "content": "Motor cortex reflexes associated with learned movement. In primates, sensory input can generate reflex motor cortex output in association with learned movement when the sensory input has a strong and direct connection to the motor cortex-for example, when a stimulus calling for repositioning of the hand consists of a perturbation of hand position. This finding supports the proposal that neurons of primate motor cortex may function in a transcortical servo-loop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196171"} {"pmid": "4196170", "title": "Polychlorinated biphenyl- and triphenyl-induced gastric mucosal hyperplasia in primates.", "content": "Polychlorinated biphenyl- and triphenyl-induced gastric mucosal hyperplasia in primates. Polychlorinated biphenyl or triphenyl ingestion by subhuman primates for 3 months produced hyperplasia and dysplasia of the gastric mucosa. The concentration of the biphenyl within the experimental diet was less than an order of magnitude greater than that occurring in random food samples sold in the United States and less than levels which have occurred in food products as a result of industrial accidents. The increased cellularity, abnormal dysplastic growth pattern, and invasion of the adjacent tissue region indicate compromised gastric function and are suggestive of an eventual neoplastic transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196170"} {"pmid": "4196176", "title": "Reproductive function in the human male. Report of a WHO scientific group.", "content": "Reproductive function in the human male. Report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196176"} {"pmid": "4196177", "title": "The Medical Society of Copenhagen 1772-1972.", "content": "The Medical Society of Copenhagen 1772-1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196177"} {"pmid": "4196178", "title": "Health hazards in the use of the laser microprobe for toxic and infective samples.", "content": "Health hazards in the use of the laser microprobe for toxic and infective samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196178"} {"pmid": "4196179", "title": "The anginal syndrome associated with normal coronary arteriograms. Report of a six year experience.", "content": "The anginal syndrome associated with normal coronary arteriograms. Report of a six year experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196179"} {"pmid": "4196180", "title": "Oxidation of catechol in plants. 3. Purification and properties of the diphenylene dioxide 2,3-quinone-forming enzyme system from Tecoma leaves.", "content": "Oxidation of catechol in plants. 3. Purification and properties of the diphenylene dioxide 2,3-quinone-forming enzyme system from Tecoma leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196180"} {"pmid": "4196182", "title": "Fat metabolism in higher plants. LVI. Distribution and nature of biotin in chloroplasts of different plant species.", "content": "Fat metabolism in higher plants. LVI. Distribution and nature of biotin in chloroplasts of different plant species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196182"} {"pmid": "4196181", "title": "The characterization and regulatory properties of pyruvate kinase from cotton seeds.", "content": "The characterization and regulatory properties of pyruvate kinase from cotton seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196181"} {"pmid": "4196183", "title": "Structure and function of amylases. II. Multiple forms of bacillus subtilis -amylase.", "content": "Structure and function of amylases. II. Multiple forms of bacillus subtilis -amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196183"} {"pmid": "4196184", "title": "Carbonic anhydrase catalyzed oxygen-18 exchange between bicarbonate and water.", "content": "Carbonic anhydrase catalyzed oxygen-18 exchange between bicarbonate and water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196184"} {"pmid": "4196185", "title": "Recovery of function: implications for theories of brain function.", "content": "Recovery of function: implications for theories of brain function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196185"} {"pmid": "4196187", "title": "The effects of vibratory and electrical stimulation on habituation in the ciliated protozoan, Spirostomum ambiguum.", "content": "The effects of vibratory and electrical stimulation on habituation in the ciliated protozoan, Spirostomum ambiguum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196187"} {"pmid": "4196186", "title": "The hippocampus and behavioral maturation.", "content": "The hippocampus and behavioral maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196186"} {"pmid": "4196188", "title": "The involvement of calcium in contractility in the ciliated protozoan, Spirostomum ambiguum.", "content": "The involvement of calcium in contractility in the ciliated protozoan, Spirostomum ambiguum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196188"} {"pmid": "4196189", "title": "Fluorescence polarization and pigment orientation in photosynthetic bacteria.", "content": "Fluorescence polarization and pigment orientation in photosynthetic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196189"} {"pmid": "4196190", "title": "Role of cell wall antolysin in chain formation by a mutant strain of Streptococcus faecalis.", "content": "Role of cell wall antolysin in chain formation by a mutant strain of Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196190"} {"pmid": "4196191", "title": "Effects of calcium and bound sialic acid on the viscosity of mucin.", "content": "Effects of calcium and bound sialic acid on the viscosity of mucin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196191"} {"pmid": "4196192", "title": "Representation of the cochlear partition of the superior temporal plane of the macaque monkey.", "content": "Representation of the cochlear partition of the superior temporal plane of the macaque monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196192"} {"pmid": "4196193", "title": "Sulfatide synthesis in neurons: a defect in mice with a hereditary myelination disorder.", "content": "Sulfatide synthesis in neurons: a defect in mice with a hereditary myelination disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196193"} {"pmid": "4196194", "title": "Distinct projections to the red nucleus from the dentate and interposed nuclei in the monkey.", "content": "Distinct projections to the red nucleus from the dentate and interposed nuclei in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196194"} {"pmid": "4196195", "title": "Lithium stimulates secretion of acetylcholine in the absence of extracellular calcium.", "content": "Lithium stimulates secretion of acetylcholine in the absence of extracellular calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196195"} {"pmid": "4196196", "title": "Brain amino acids in baboons with light-induced epilepsy.", "content": "Brain amino acids in baboons with light-induced epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196196"} {"pmid": "4196198", "title": "Human prolactin.", "content": "Human prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196198"} {"pmid": "4196199", "title": "Isolation and partial characterization of immunoglobulin from a urodele amphibian (Necturus masculosus).", "content": "Isolation and partial characterization of immunoglobulin from a urodele amphibian (Necturus masculosus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196199"} {"pmid": "4196200", "title": "The bentonite granuloma. Characterization of a model system for infectious and foreign body granulomatous inflammation using soluble mycobacterial, histoplasma and schistosoma antigens.", "content": "The bentonite granuloma. Characterization of a model system for infectious and foreign body granulomatous inflammation using soluble mycobacterial, histoplasma and schistosoma antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196200"} {"pmid": "4196201", "title": "Quantitative analysis of activity in eye muscle motoneurons during saccadic eye movements and positions of fixation.", "content": "Quantitative analysis of activity in eye muscle motoneurons during saccadic eye movements and positions of fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196201"} {"pmid": "4196202", "title": "Influence of saccadic eye movements on unit activity in simian lateral geniculate and pregeniculate nuclei.", "content": "Influence of saccadic eye movements on unit activity in simian lateral geniculate and pregeniculate nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196202"} {"pmid": "4196203", "title": "Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory.", "content": "Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196203"} {"pmid": "4196204", "title": "GLC determination of nitroglycerin and isosorbide dinitrate in human plasma.", "content": "GLC determination of nitroglycerin and isosorbide dinitrate in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196204"} {"pmid": "4196205", "title": "Kinetics of -lactamase inactivation of penicillins I: effect of side-chain structure, ionic strength, pH, and temperature.", "content": "Kinetics of -lactamase inactivation of penicillins I: effect of side-chain structure, ionic strength, pH, and temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196205"} {"pmid": "4196206", "title": "Selenium heterocycles. 8. Synthesis and antibacterial activity of selenosemicarbazide and 1,3,4-selenadiazolylcarbamic acid esters.", "content": "Selenium heterocycles. 8. Synthesis and antibacterial activity of selenosemicarbazide and 1,3,4-selenadiazolylcarbamic acid esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196206"} {"pmid": "4196207", "title": "Field application of immunodiffusion and complement fixation tests for diagnosis of equine infectious anemia.", "content": "Field application of immunodiffusion and complement fixation tests for diagnosis of equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196207"} {"pmid": "4196208", "title": "Relationship between histopathological and serological findings in field cases of equine infectious anemia.", "content": "Relationship between histopathological and serological findings in field cases of equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196208"} {"pmid": "4196209", "title": "Some characteristics of high macarbomycin-resistant mutants of Escherichia coli isolated from gnotobiotic pigs.", "content": "Some characteristics of high macarbomycin-resistant mutants of Escherichia coli isolated from gnotobiotic pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196209"} {"pmid": "4196210", "title": "Short term heritable changes affecting viability in Drosophila melanogaster.", "content": "Short term heritable changes affecting viability in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196210"} {"pmid": "4196214", "title": "Blood carbonic anhydrase activity in the newborn.", "content": "Blood carbonic anhydrase activity in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196214"} {"pmid": "4196215", "title": "Total intravenous nutrition. Experience with fat emulsions and hypertonic glucose.", "content": "Total intravenous nutrition. Experience with fat emulsions and hypertonic glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196215"} {"pmid": "4196216", "title": "Prevention of postoperative ketosis in the diabetic. Use of high-caloric intravenous solutions.", "content": "Prevention of postoperative ketosis in the diabetic. Use of high-caloric intravenous solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196216"} {"pmid": "4196217", "title": "Venobronchial fistula. A rare complication of central venous catheterization for parenteral hyperalimentation.", "content": "Venobronchial fistula. A rare complication of central venous catheterization for parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196217"} {"pmid": "4196218", "title": "Photic stimulation and visual physiology: implications for behavioral studies.", "content": "Photic stimulation and visual physiology: implications for behavioral studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196218"} {"pmid": "4196219", "title": "Reversal learning in the developing malnourished rhesus monkey.", "content": "Reversal learning in the developing malnourished rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196219"} {"pmid": "4196220", "title": "H-2 histocompatibility alloantigens. Some biochemical properties of the molecules solubilized by NP-40 detergent.", "content": "H-2 histocompatibility alloantigens. Some biochemical properties of the molecules solubilized by NP-40 detergent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196220"} {"pmid": "4196221", "title": "RNA polymerase from vegetative cells and spores of Bacillus cereus T. II. Peptide composition.", "content": "RNA polymerase from vegetative cells and spores of Bacillus cereus T. II. Peptide composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196221"} {"pmid": "4196222", "title": "The reaction of hydroxylamine with 4-thiouridine.", "content": "The reaction of hydroxylamine with 4-thiouridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196222"} {"pmid": "4196223", "title": "The regulation of cell growth. I. Identification and partial characterization of a DNA synthesis stimulating factor from the serum of partially hepatectomized rats.", "content": "The regulation of cell growth. I. Identification and partial characterization of a DNA synthesis stimulating factor from the serum of partially hepatectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196223"} {"pmid": "4196225", "title": "Exploratory behavior of cebus monkeys after having been reared in partial isolation.", "content": "Exploratory behavior of cebus monkeys after having been reared in partial isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196225"} {"pmid": "4196224", "title": "Colour coding in rhesus monkey prestriate cortex.", "content": "Colour coding in rhesus monkey prestriate cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196224"} {"pmid": "4196226", "title": "Tacitin: a preliminary evaluation in chronic alcoholic patients presenting the target symptomatology of anxiety.", "content": "Tacitin: a preliminary evaluation in chronic alcoholic patients presenting the target symptomatology of anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196226"} {"pmid": "4196227", "title": "Thioridazine for newly admitted psychiatric patients.", "content": "Thioridazine for newly admitted psychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196227"} {"pmid": "4196229", "title": "Clinical evaluation of a possible catechol-O-methyl transferase inhibitor in endogenous depression.", "content": "Clinical evaluation of a possible catechol-O-methyl transferase inhibitor in endogenous depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196229"} {"pmid": "4196230", "title": "Topical clotrimazole in dermatophytosis.", "content": "Topical clotrimazole in dermatophytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196230"} {"pmid": "4196228", "title": "U-28,774 (ketozolam): an early evaluation of a new antianxiety agent.", "content": "U-28,774 (ketozolam): an early evaluation of a new antianxiety agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196228"} {"pmid": "4196232", "title": "The use of fluphenazine enanthate in psychotic patients.", "content": "The use of fluphenazine enanthate in psychotic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196232"} {"pmid": "4196231", "title": "Chlorazepate dipotassium in the treatment of anxiety associated with chronic gastrointestinal disease.", "content": "Chlorazepate dipotassium in the treatment of anxiety associated with chronic gastrointestinal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196231"} {"pmid": "4196233", "title": "A double blind, phase I clinical study oxazepam and protriptyline combined.", "content": "A double blind, phase I clinical study oxazepam and protriptyline combined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196233"} {"pmid": "4196234", "title": "Hemocytic changes associated with the encapsulation and melanization of some insect parasites.", "content": "Hemocytic changes associated with the encapsulation and melanization of some insect parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196234"} {"pmid": "4196237", "title": "The cutaneous mucinoses.", "content": "The cutaneous mucinoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196237"} {"pmid": "4196238", "title": "Mast cell infiltrates of the skin and the mastocytosis syndrome.", "content": "Mast cell infiltrates of the skin and the mastocytosis syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196238"} {"pmid": "4196239", "title": "Temperature-sensitive initiation of chromosome replication in a mutant of Bacillus subtilis.", "content": "Temperature-sensitive initiation of chromosome replication in a mutant of Bacillus subtilis. A mutant of Bacillus subtilis Ts37 has been isolated in which deoxyribonucleic acid (DNA) synthesis is inhibited at high temperature. The results presented here indicate that the process of initiation of DNA replication is temperature sensitive in this mutant. After shifting to 45 C, DNA increases 40 to 50% before synthesis ceases; an inhibition of protein synthesis permits an equivalent amount of DNA to be synthesized. A density shift experiment coupled with a marker frequency analysis shows that DNA synthesized at 45 C is highly enriched in the markers situated at the end of the chromosome. Transforming DNA extracted from a culture which has been incubated at 45 C exhibits the relative transforming efficiency for origin and terminus markers characteristic of completed chromosomes. After a shift back from 45 C to 30 C, reinitiation appears to occur always in the same region of the bacterial chromosome; in addition, replication as well as cell division is synchronized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196239"} {"pmid": "4196240", "title": "Acid-base titration of streptococci and the physical states of intracellular ions.", "content": "Acid-base titration of streptococci and the physical states of intracellular ions. Acid titrations of intact and butanol-treated cells of Streptococcus faecalis revealed that nearly all of the intracellular K(+) ions could diffuse into the suspending medium in association with small anions, including ribonucleic acid breakdown products, when the cell membrane was damaged. In contrast, nearly all of the intracellular Mg(2+) ions appeared to be firmly bound to stable internal cell components but could be displaced reversibly by hydronium ions. The cell membrane acted as a barrier to ion movements, and Mg(2+) displacement from intact cells required more acid conditions, by as much as 2.5 pH units, than did displacement from butanol-damaged cells. Some 15 to 20% of the cell magnesium appeared to be associated with surface structures in that it could be removed at pH 7 with ethylenediaminetetraacetic acid or displaced by Co(2+), Ni(2+), Sr(2+), or La(3+). Magnesium could be displaced from isolated cell walls and membranes by hydronium ions in the pH range from 5 to 3, over which carboxyl groups were titrated. Displacement of magnesium from ribosomes also took place between pH 5 and 3, but it was more difficult to identify the magnesium-releasing groups because both protein carboxyl groups and purine and pyrimidine ring nitrogens can become protonated in this pH range. Isolated protoplast membranes remained structurally intact when completely depleted of magnesium. Furthermore, protoplasts isolated from intact cells were found to have greatly enhanced resistance to osmotic shock in acid media, even when solute loss was not extensive. Osmotic resistance was lost when the protoplasts were again placed in neutral media, and this reversibility suggested that acidification caused changes in the physical properties of membranes as well as solute leakage from cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196240"} {"pmid": "4196241", "title": "Macromolecular syntheses during germination and outgrowth of Bacillus subtilis spores.", "content": "Macromolecular syntheses during germination and outgrowth of Bacillus subtilis spores. Alanine and glucose used jointly are known to be necessary and sufficient for spore germination in Bacillus subtilis 168. By testing them separately, we have verified that alanine provokes optimal phase-darkening of the spores but inhibits macromolecular syntheses, while glucose is specifically needed for initiating those syntheses. By using them in succession we obtained evidence suggesting that: (i) sporal modifications which lead to phase-darkening must occur before macromolecular synthesis can start; (ii) the amino acid pool, on which the early protein synthesis is solely dependent, expands during incubation in alanine which allows degradative but prevents synthetic activities; and (iii) progression of degradations in alanine not promptly followed by syntheses in glucose produce a metabolic imbalance in the germinating spore. A sharp transition in the origin of building blocks was shown by using a tryptophan-defective mutant. At first the synthesis of proteins depended on pre-existing amino acids from turnover of sporal material since it occurred in the absence of any exogenous amino acid and its rate remained unaltered by supplying either all amino acids except tryptophan or tryptophan alone. Eventually, protein synthesis became dependent strictly on exogenous tryptophan and strongly on the supply of several other amino acids, not required later during vegetative growth. Clearly, by the start of outgrowth, all building blocks must be provided either by endogenous de novo synthesis or by exogenous supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196241"} {"pmid": "4196242", "title": "Inactivation of aspartic transcarbamylase in sporulating Bacillus subtilis: demonstration of a requirement for metabolic energy.", "content": "Inactivation of aspartic transcarbamylase in sporulating Bacillus subtilis: demonstration of a requirement for metabolic energy. The aspartic transcarbamylase (ATCase) activity of Bacillus subtilis cells disappears rapidly from stationary-phase cells prior to sporulation. ATCase activity does not appear in the culture fluid during the stationary phase; hence the enzyme appears to be inactivated in the cells. The enzyme is inactivated normally in two different mutants lacking proteases; the activity is very stable in crude extracts of cells or in the culture fluid. These results suggest that ATCase is not inactivated by the general proteolysis that occurs in sporulating bacteria. The inactivation of ATCase can be completely inhibited after it has begun by oxygen starvation or addition of fluoroacetate. Inhibitors of oxidative phosphorylation and electron transport also interrupt the inactivation of ATCase. The inactivation of ATCase is very slow in two mutant strains that are deficient in enzymes of tricarboxylic acid cycle. Addition of gluconate to stationary cultures of the mutant strains, which is known to restore depleted adenosine 5'-triphosphate pools in these bacteria, also restores inactivation of ATCase. These experiments support the conclusion that the generation of metabolic energy is necessary for the inactivation of ATCase in stationary cells. ATCase activity is stable in growing cells in which ATCase synthesis is repressed by addition of uracil; the enzyme is inactivated normally, however, when such cells cease growing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196242"} {"pmid": "4196243", "title": "Penicillin-binding component of Bacillus cereus.", "content": "Penicillin-binding component of Bacillus cereus. (14)C-penicillin is irreversibly bound by Bacillus cereus 569. Incubation of penicillin-treated cells in a cell wall digestion medium results in solubilization of approximately 60% of the irreversibly bound lable. The extent of the solubilization is the same when cells are prepared by either a cold or 37 C treatment procedure. However, spheroplasts prepared by the cold treatment are leaky. When the resulting spheroplasts are incubated in supplemented medium, reduced rates and levels of penicillinase synthesis, relative to induced whole-cell controls, are observed. Spheroplasts from both cold and 37 C prepared cells exhibit this phenomena, although the spheroplasts from 37 C prepared cells synthesized approximately sixfold higher levels of penicillinase. The size distribution of the label solubilized during the preparation of spheroplasts was examined by using Bio Gel P-150 columns. Although no label appeared in the exclusion volume fractions when the cell wall digest of the 37 C treated cells was chromatographed, approximately 10% of the label from cold-treated cells did appear. These results suggest that the presence of irreversibly bound penicillin is required for the synthesis of induced levels of penicillinase and that the irreversibly bound penicillin can be solubilized as a labile complex with material which is excluded from BioGel P-150. It may be concluded that the penicillin-binding lipoprotein complex which has been previously observed is the penicillin-specific binding site. However, the location of this complex in relation to the cell membrane could not be determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196243"} {"pmid": "4196245", "title": "Association of many regions of the Bacillus subtilis chromosome with the cell membrane.", "content": "Association of many regions of the Bacillus subtilis chromosome with the cell membrane. Unsheared lysates of Bacillus subtilis 168T(-) containing uniformly labeled deoxyribonucleic acid (DNA) were exposed to varying doses of gamma rays to introduce double-strand scissions in the chromosome. From an estimate of the number-average molecular weight and the amount of DNA bound to membrane after irradiation, about 70 to 90 regions of the bacterial chromosome were detected in membrane fractions. Since this number was independent of the molecular weight of the DNA (i.e., the extent of fragmentation of the chromosome), it is thought to represent an upper limit in the number of membrane-binding sites per chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196245"} {"pmid": "4196244", "title": "Induction of superoxide dismutase by molecular oxygen.", "content": "Induction of superoxide dismutase by molecular oxygen. Oxygen induces superoxide dismutase in Streptococcus faecalis and in Escherichia coli B. S. faecalis grown under 20 atm of O(2) had 16 times more of this enzyme than did anaerobically grown cells. In the case of E. coli, changing the conditions of growth from anaerobic to 5 atm of O(2) caused a 25-fold increase in the level of superoxide dismutase. Induction of this enzyme was a response to O(2) rather than to pressure, since 20 atm of N(2) was without effect. Induction of superoxide dismutase was a rapid process, and half of the maximal level was reached within 90 min after N(2)-grown cells of S. faecalis were exposed to 20 atm of O(2) at 37 C. S. faecalis did not contain perceptible levels of catalase under any of the growth conditions investigated by Stanier, Doudoroff, and Adelberg (23), and the concentration of catalase in E. coli was not affected by the presence of O(2) during growth. S. faecalis, which had been grown under 100% O(2) and which therefore contained an elevated level of superoxide dismutase, was more resistant of 46 atm of O(2) than were cells which had been grown under N(2). E. coli grown under N(2) contained as much superoxide dismutase as did S. faecalis grown under 1 atm of O(2). The E. coli which had been grown under N(2) was as resistant to the deleterious effects of 50 atm of O(2) as was S. faecalis which had been grown under 1 atm of O(2). These results are consistent with the proposal that the peroxide radical is an important agent of the toxicity of oxygen and that superoxide dismutase may be a component of the systems which have been evolved to deal with this potential toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196244"} {"pmid": "4196246", "title": "Intergeneric complementation of anthranilate synthase subunits.", "content": "Intergeneric complementation of anthranilate synthase subunits. Partially purified subunits of anthranilate synthase were prepared from Bacillus subtilis and Pseudomonas aeruginosa. The large component from B. subtilis (I(B)) complements well with the small component from P. aeruginosa (II(P)) to reconstitute a glutamine-reactive anthranilate synthase. This interaction can be demonstrated with crude extracts from a B. subtilis trpX mutant and a P. aeruginosa trpA mutant. Complementation was also observed with the large component from P. aeruginosa (I(P)) and the small subunit from B. subtilis (II(B)). At saturation the heterologous complex I(B)II(P) has 93% of the activity of the homologous complex I(B)II(B), whereas the hybrid I(P)II(B) is only 22% as active as the homologous complex I(P)II(P).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196246"} {"pmid": "4196247", "title": "Effects of mutational loss of specific intracellular proteases on the sporulation of Bacillus subtilis.", "content": "Effects of mutational loss of specific intracellular proteases on the sporulation of Bacillus subtilis. Two protease-deficient mutants of Bacillus subtilis 168 (Trp(-)) were isolated and compared with the parental strain with respect to production of intracellular proteases and sporulation. A mutant lacking the metal-requiring \"neutral\" protease intracellularly sporulated as well as the parental strain. A second mutant, deficient in an as yet uncharacterized intracellular protease, failed to sporulate normally. It is proposed that this new protease is also involved in intracellular protein turnover.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196247"} {"pmid": "4196248", "title": "Characterization of the polydisperse closed circular deoxyribonucleic acid molecules of Bacillus megaterium.", "content": "Characterization of the polydisperse closed circular deoxyribonucleic acid molecules of Bacillus megaterium. The polydisperse circular deoxyribonucleic acid (DNA) molecules which comprise up to 30% of the total extractable DNA of Bacillus megaterium strain 216 have been purified and partially characterized. Banding in cesium chlorideethidium bromide by \"gradient relaxation\" in a fixed-angle rotor provided good resolution of circular and chromosomal DNAs for preparative separations. Renaturation studies on purified circular DNA failed to reveal a rapidly renaturing fraction, and DNA-DNA hybridization studies indicated that the majority of the chromosomal nucleotide sequences are represented in the heterogeneous-size population of circular molecules. It is concluded that the circular DNA of B. megaterium does not represent typical bacterial plasmid DNA. The possibility that the circular DNA molecules are the result of the expression of a defective bacteriophage is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196248"} {"pmid": "4196249", "title": "Role of intestinal microflora in the metabolism of guanidinosuccinic acid.", "content": "Role of intestinal microflora in the metabolism of guanidinosuccinic acid. Among a variety of bacteria isolated from the gastrointestinal tracts of rats and humans, only streptococci of group N are capable of degrading guanidinosuccinic acid added to their culture medium. The urinary excretion of guanidinosuccinic acid by germfree rats is greater than that of conventional rats. The excretion of this compound by gnotobiotic rats correlates with the capacity of their intestinal microflora to degrade guanidinosuccinic acid in culture. Thus, guanidinosuccinic acid excretion is low in rats infected exclusively with Streptococcus faecalis, and the excretion is not altered when germfree rats are infected with an organism unable to degrade guanidinosuccinic acid (Lactobacillus). These findings suggest that the intestinal microflora, particularly Streptococcus, play a role in the metabolism of guanidinosuccinic acid by the host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196249"} {"pmid": "4196250", "title": "Chorismate mutase from Streptomyces aureofaciens: a heat-stable enzyme.", "content": "Chorismate mutase from Streptomyces aureofaciens: a heat-stable enzyme. Chorismate mutase from Streptomyces aureofaciens was purified 12-fold. This enzyme preparation did not show any activity when tested for anthranilate synthetase, prephenate dehydrogenase, or prephenate dehydratase. The catalytic activity of chorismate mutase has a broad optimum between pH 7 and 8. The initial velocity data followed regular Michaelis-Menten kinetics with a K(m) of 5.3 x 10(-4) M, and the molecular weight of the enzyme was determined by sucrose gradient centrifugation to be 50,000. Heat inactivation of chorismate mutase, which occurs above temperatures of 60 C, is reversible. The enzyme activity can be restored even when chorismate mutase is treated at the temperature of a boiling-water bath for 15 min. Heat-denatured and renatured enzymes showed the same Michaelis constant and the same molecular weight as the native enzyme. l-Phenylalanine, l-tyrosine, l-tryptophan, and metabolites of the aromatic amino acid pathway were tested as potential modifiers of chorismate mutase activity. The activity of the enzyme was inhibited by none of these substances. Chorismate mutase of S. aureofaciens was not repressed in cells grown in minimal medium supplemented with l-phenylalanine, l-tyrosine, or l-tryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196250"} {"pmid": "4196251", "title": "Escherichia coli mutants permissive for T4 bacteriophage with deletion in e gene (phage lysozyme).", "content": "Escherichia coli mutants permissive for T4 bacteriophage with deletion in e gene (phage lysozyme). Escherichia coli mutants have been isolated that are permissive for the infection by T4 phage with deletion in the cistron for the phage lysozyme, the e gene. Some, but not all, of these mutants are simultaneously permissive for the infection by T4 phage defective in the t gene, the product of which has also been implicated in the release of progeny phages. Most of these mutants shared the following properties: temperature sensitivity in growth and cell division, increased sensitivity towards a number of unrelated antibiotics and colicins, and increased sensitivity towards anionic detergents (sodium dodecyl sulfate and sodium deoxycholate). The possible biochemical basis for these phenotypes is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196251"} {"pmid": "4196253", "title": "Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria (algae): photoheterotrophic growth of an \"autotrophic\" blue-green bacterium.", "content": "Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria (algae): photoheterotrophic growth of an \"autotrophic\" blue-green bacterium. The unicellular blue-green bacterium Agmenellum quadruplicatum strain BG-1 was found to be capable of rapid photoheterotrophic growth but unable to grow in the dark on a variety of reduced organic substrates. The generation time on glycerol was 12 h, and on CO(2), 3 h. Glycerol carbon was converted into cellular carbon with a very high efficiency. This high efficiency of carbon conversion, the action spectrum for growth on glycerol, cell pigmentation, gas exchange measurements, and immediate ability of photoheterotrophically grown cells to evolve O(2) (upon the addition of CO(2)) suggest the involvement of both photosystems I and II of photosynthesis during photoheterotrophic growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196253"} {"pmid": "4196252", "title": "Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria (algae): photoheterotrophic growth of a \"heterotrophic\" blue-green bacterium.", "content": "Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria (algae): photoheterotrophic growth of a \"heterotrophic\" blue-green bacterium. Nostoc sp. (strain Mac) was shown to be capable of using glucose, fructose, or sucrose as a sole source of carbon and energy in the dark. In the light in the absence of exogenously supplied CO(2), this strain exhibited a more versatile metabolism. In addition to the three sugars above, glycerol and acetate served as sole sources of carbon. This photoheterotrophic growth in the absence of exogenously supplied CO(2) appears to involve O(2)-evolving photosynthesis. The action spectrum for photoheterotrophic growth on acetate closely resembles the action spectrum for photosynthesis. The physiology of photoheterotrophic growth was further investigated through determinations of stable carbon isotope ratios and measurements of gas exchanges. These investigations suggest that respired CO(2) from substrate oxidation is assimilated by the photosynthetic machinery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196252"} {"pmid": "4196254", "title": "Deoxyribonucleic acid-membrane complexes in the Bacillus subtilis transformation system.", "content": "Deoxyribonucleic acid-membrane complexes in the Bacillus subtilis transformation system. The fate of transforming deoxyribonucleic acid (DNA) in Bacillus subtilis was studied by isolating the DNA-membrane complex on Renografin gradients. Soon after uptake, transforming DNA binds to the cell membrane and displays a greater resistance to shear than the recipient genome-membrane complex. Ten minutes after uptake, a portion of the donor DNA is released from the membrane. Most of the released donor radioactivity represents unintegrated, biologically inactive DNA. Recombinant or integrated DNA is enriched 1.5- to 1.7-fold in the membrane. This enrichment last at least 30 min after termination of DNA uptake, and probably much longer. The data suggest that transforming DNA may be integrated into the recipient genome on, or close to, the cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196254"} {"pmid": "4196255", "title": "Structural difference between walls from hemispherical caps and partial septa of Bacillus subtilis.", "content": "Structural difference between walls from hemispherical caps and partial septa of Bacillus subtilis. Walls from partial septa of Bacillus subtilis bacteria are more sensitive than end walls to digestion by B. subtilis autolytic amidase. This result indicates that, after synthesis, B. subtilis septal walls are modified to an amidase-resistant form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196255"} {"pmid": "4196256", "title": "Mutant of Bacillus subtilis with a temperature-sensitive autolytic amidase.", "content": "Mutant of Bacillus subtilis with a temperature-sensitive autolytic amidase. A procedure incorporating a petri plate assay for autolysins has been developed for the systematic isolation of mutants with a temperature-sensitive autolytic amidase. We suggest maa as the name for the gene for this enzyme. One such mutant has been characterized as having a heat-sensitive amidase in a variety of studies with both crude autolysin preparations and purified amidase solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196256"} {"pmid": "4196257", "title": "Micrococcus lysodeikticus bacterial walls as a substrate specific for the autolytic glycosidase of Bacillus subtilis.", "content": "Micrococcus lysodeikticus bacterial walls as a substrate specific for the autolytic glycosidase of Bacillus subtilis. The Bacillus subtilis 168 autolytic glycosidase degrades Micrococcus lysodeikticus cells or cell walls, whereas the B. subtilis autolytic amidase does not. The criteria used to establish this fact included: the determination of chemical bonds broken, heat-inactivated kinetics, pH dependence curves, and the physical separation of glycosidase from amidase. The physical separation involved LiCl elution from two different ion-exchange materials, walls from B. subtilis 168 strain betaAO, and walls from mutant strain betaA173 derived from strain betaAO. No evidence was obtained for B. subtilis vegetative bacteria making any more autolysins than one autolytic amidase and one autolytic glycosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196257"} {"pmid": "4196258", "title": "Large surface blebs on Escherichia coli heated to inactivating temperatures.", "content": "Large surface blebs on Escherichia coli heated to inactivating temperatures. Large surface blebs were observed with phase-contrast optics on Escherichia coli B/r and B(s-1) heated to temperatures at which colony-forming ability was lost. Characterization of such blebs was consistent with the view that they were formed by a physical process and were bounded by the outer membrane of the cell. A hypothesis for thermal inactivation of E. coli is presented that places membrane damage near the primary lethal event.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196258"} {"pmid": "4196260", "title": "Stimulation of cell division by croton oil in blue-green bacteria.", "content": "Stimulation of cell division by croton oil in blue-green bacteria. The potent tumor-promoting agent croton oil, which has been shown previously to be strongly mitogenic in mammalian cells, stimulates cell division in snake mutants of the blue-green bacterium Agmenellum quadruplicatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196260"} {"pmid": "4196259", "title": "Minicells of Bacillus subtilis.", "content": "Minicells of Bacillus subtilis. After nitrosoguanidine (N-methyl-N'-nitro-N-nitrosoguanidine) mutagenesis, two Bacillus subtilis mutants (div IV-A1 and div IV-B1) were isolated that are defective in the location of division site along cell length. Both mutations were transferred into strain CU403 by transformation, and their properties were studied in the CU403 genetic background. Location of divisions in close proximity to cell pole regions in both mutants results in minicell production. Purified minicells contain a ratio of ribonucleic acid to protein comparable to that found in the parent cells. Autoradiographs of (3)H-thymine incorporation into deoxyribonucleic acid (DNA), thymine-2-(14)C incorporation into DNA, electron micrographs, and chemical analyses for DNA all fail to demonstrate DNA in the minicells. Minicells produced by both mutants are highly motile, an indication of functional energy metabolism. Electron micrographs reveal that minicells are produced by a structurally normal division mechanism and that minicells contain a normal cell surface. The div IV-A1 mutation has been mapped by PBS1 transduction linked to ura. The div IV-B1 mutation is closely linked to pheA by both PBS1 transduction and by co-transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196259"} {"pmid": "4196261", "title": "Influence of magnesium ions on porosity of the Bacillus megaterium cell wall and membrane.", "content": "Influence of magnesium ions on porosity of the Bacillus megaterium cell wall and membrane. The presence of magnesium chloride (0.01 M) caused a relatively small but significant reduction in the equivalent porosity of the protoplast membrane, but not in that of the cell wall, in intact Bacillus megaterium cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196261"} {"pmid": "4196262", "title": "Prolactin response to thyrotropin releasing hormone in normal subjects.", "content": "Prolactin response to thyrotropin releasing hormone in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196262"} {"pmid": "4196263", "title": "Changes in iodine metabolism and thyroglobulin structure in metastatic follicular carcinoma of the thyroid with hyperthyroidism.", "content": "Changes in iodine metabolism and thyroglobulin structure in metastatic follicular carcinoma of the thyroid with hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196263"} {"pmid": "4196264", "title": "L-dopa suppression of TRH-stimulated prolactin release in man.", "content": "L-dopa suppression of TRH-stimulated prolactin release in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196264"} {"pmid": "4196265", "title": "Plasma growth hormone response to thyrotropin-releasing hormone in patients with active acromegaly.", "content": "Plasma growth hormone response to thyrotropin-releasing hormone in patients with active acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196265"} {"pmid": "4196266", "title": "The structure of the medial geniculate nucleus (MGN): a cyto- and myeloarchitectonic study in the squirrel monkey.", "content": "The structure of the medial geniculate nucleus (MGN): a cyto- and myeloarchitectonic study in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196266"} {"pmid": "4196267", "title": "Control of responding by location of auditory stimuli: role of differential and non-differential reinforcement.", "content": "Control of responding by location of auditory stimuli: role of differential and non-differential reinforcement. Sound was presented to monkeys through one of two loudspeakers, each adjacent to a response key. A response on the key adjacent to the sound source was reinforced (correct response). A response on the other key produced a timeout (incorrect response). Under these conditions, over 90% of responses were correct within one or two sessions. When the procedure was changed so that a response on either key was reinforced independently of which speaker was sounding, similar control by location developed within one or two sessions. When conditions were modified by moving the keys away from the immediate vicinity of the speakers, the animals required about 20 sessions to reach a stable level of greater than 90% correct responses under differential reinforcement conditions. No control by location developed under nondifferential reinforcement conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196267"} {"pmid": "4196268", "title": "Behavioral assessment of pain detection and tolerance in monkeys.", "content": "Behavioral assessment of pain detection and tolerance in monkeys. Cebus albifrons monkeys received electrical stimulation of the hindlimbs over a wide range of intensities. On trials signalled by a blue light, the animals were permitted to escape shock by pressing a disc, or shock was terminated after 8 sec (free escape). Escape force (disc pressure) was found to increase as stimulation intensity increased well beyond escape threshold, while shock duration curves reached plateau at the mid-range of intensities. The shock duration curves generated by free escape responses should be comparable to pain detection functions obtained by similar operations in humans, and the curves were stable over months of testing, as is generally found in pain-detection studies. On trials signalled by a red light, the animals received intense tail shock immediately after escape responses (punished escape), or, if they endured leg shock for 8 sec without escaping, then they could avoid tail shock with a panel press. The shock duration curves generated by punished escape responses should be comparable to pain tolerance functions as defined for human subjects, and the escape thresholds were considerably higher on red-light trials. As in human studies, the tolerance curves were not stable over repeated testing sessions, and some feature of the paradigm forced a progression toward extremely high levels of tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196268"} {"pmid": "4196269", "title": "Operantly conditioned patterns on precentral unit activity and correlated responses in adjacent cells and contralateral muscles.", "content": "Operantly conditioned patterns on precentral unit activity and correlated responses in adjacent cells and contralateral muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196269"} {"pmid": "4196270", "title": "Hippocampal influence on unit activity of hypothalamus, preoptic region, and basal forebrain in awake, stting squirrel monkeys.", "content": "Hippocampal influence on unit activity of hypothalamus, preoptic region, and basal forebrain in awake, stting squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196270"} {"pmid": "4196271", "title": "\"Cold\" fiber population innervating palmar and digital skin of the monkey: responses to cooling pulses.", "content": "\"Cold\" fiber population innervating palmar and digital skin of the monkey: responses to cooling pulses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196271"} {"pmid": "4196272", "title": "Peripheral neural determinants of temperature discrimination in man: a correlative study of responses to cooling skin.", "content": "Peripheral neural determinants of temperature discrimination in man: a correlative study of responses to cooling skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196272"} {"pmid": "4196275", "title": "Survival of common bacteria in liquid culture under carbon dioxide at high temperatures.", "content": "Survival of common bacteria in liquid culture under carbon dioxide at high temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196275"} {"pmid": "4196277", "title": "A Rhesus incompatible baby.", "content": "A Rhesus incompatible baby.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196277"} {"pmid": "4196279", "title": "The proximal negative response of the primate retina.", "content": "The proximal negative response of the primate retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196279"} {"pmid": "4196278", "title": "Estrogen formation by the isolated perfused rhesus monkey brain.", "content": "Estrogen formation by the isolated perfused rhesus monkey brain. Perfusion of two isolated brains from immature male rhesus monkeys with [(3)H]androstenedione resulted in the identification of free and conjugated [(3)H]estrone and free [(3)H]estradiol from the perfusates. In the dissected cerebral tissues, estrogens were recovered only from the hypothalamus and limbic system. The production of estrogens from androstenedione during the 40-minute perfusions in these two experiments totaled 1.58 and 2.83 nanograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196278"} {"pmid": "4196281", "title": "Thyroidectomy cells and their response to thyrotrophin releasing hormone (TRH) in the rat.", "content": "Thyroidectomy cells and their response to thyrotrophin releasing hormone (TRH) in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196281"} {"pmid": "4196282", "title": "Serum lysozyme in pulmonary tuberculosis.", "content": "Serum lysozyme in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196282"} {"pmid": "4196284", "title": "Bullous retinal detachment. An unusual manifestation of idiopathic central serous choroidopathy.", "content": "Bullous retinal detachment. An unusual manifestation of idiopathic central serous choroidopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196284"} {"pmid": "4196283", "title": "Hypothalamic hypothyroidism: diminished thyroidal response to thyrotropin-releasing hormone.", "content": "Hypothalamic hypothyroidism: diminished thyroidal response to thyrotropin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196283"} {"pmid": "4196285", "title": "Cyclopia.", "content": "Cyclopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196285"} {"pmid": "4196286", "title": "Pilocarpine uptake by pigmented uveal tissue.", "content": "Pilocarpine uptake by pigmented uveal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196286"} {"pmid": "4196276", "title": "Morphology of receptor innervation of spinal ganglia.", "content": "Morphology of receptor innervation of spinal ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196276"} {"pmid": "4196287", "title": "Experimental infections with African trypanosomes. V. Preliminary parasitological, clinical, hematological, serological, and pathological observations in rhesus monkeys infected with Trypanosoma rhodesiense.", "content": "Experimental infections with African trypanosomes. V. Preliminary parasitological, clinical, hematological, serological, and pathological observations in rhesus monkeys infected with Trypanosoma rhodesiense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196287"} {"pmid": "4196288", "title": "Studies on the immunization of monkeys against dengue. I. Protection derived from single and sequential virus infections.", "content": "Studies on the immunization of monkeys against dengue. I. Protection derived from single and sequential virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196288"} {"pmid": "4196289", "title": "Studies on the immunization of monkeys against dengue. II. Protection following inoculation of combinations of viruses.", "content": "Studies on the immunization of monkeys against dengue. II. Protection following inoculation of combinations of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196289"} {"pmid": "4196290", "title": "Vascular changes in the anterior uvea of the rabbit produced by prostaglandins.", "content": "Vascular changes in the anterior uvea of the rabbit produced by prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196290"} {"pmid": "4196291", "title": "Expandable silicone implants for scleral buckling. I. Introduction of a new concept.", "content": "Expandable silicone implants for scleral buckling. I. Introduction of a new concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196291"} {"pmid": "4196292", "title": "Mitochondrial DNA from Drosophila melanogaster.", "content": "Mitochondrial DNA from Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196292"} {"pmid": "4196293", "title": "Postoperative wound infection in colonic and rectal surgery.", "content": "Postoperative wound infection in colonic and rectal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196293"} {"pmid": "4196294", "title": "Long-term anticoagulant treatment after myocardial infarction. A review.", "content": "Long-term anticoagulant treatment after myocardial infarction. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196294"} {"pmid": "4196308", "title": "Acute alcoholic fatty liver in the Rhesus monkey.", "content": "Acute alcoholic fatty liver in the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196308"} {"pmid": "4196309", "title": "Renal function in chronic intravascular haemolysis associated with prosthetic cardiac valves.", "content": "Renal function in chronic intravascular haemolysis associated with prosthetic cardiac valves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196309"} {"pmid": "4196310", "title": "Peptide composition of human plasma apolipoproteins A, B and C.", "content": "Peptide composition of human plasma apolipoproteins A, B and C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196310"} {"pmid": "4196314", "title": "Dietetics reaches out.", "content": "Dietetics reaches out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196314"} {"pmid": "4196316", "title": "Principles of viable preservation of parasitic Protozoa.", "content": "Principles of viable preservation of parasitic Protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196316"} {"pmid": "4196315", "title": "Immunospecific purification of human anti-IgM serum utilizing cord serum immunoadsorbent.", "content": "Immunospecific purification of human anti-IgM serum utilizing cord serum immunoadsorbent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196315"} {"pmid": "4196317", "title": "Babesia canis: the life cycle and laboratory maintenance in its arthropod and mammalian hosts.", "content": "Babesia canis: the life cycle and laboratory maintenance in its arthropod and mammalian hosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196317"} {"pmid": "4196318", "title": "Babesia argentina: the infectivity and immunogenicity of irradiated blood parasites for splenectomized calves.", "content": "Babesia argentina: the infectivity and immunogenicity of irradiated blood parasites for splenectomized calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196318"} {"pmid": "4196319", "title": "Learning in monkeys after combined lesions in frontal and anterior temporal lobes.", "content": "Learning in monkeys after combined lesions in frontal and anterior temporal lobes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196319"} {"pmid": "4196320", "title": "Matching within and between sense modalities in the monkey (Macaca mulatta).", "content": "Matching within and between sense modalities in the monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196320"} {"pmid": "4196322", "title": "Dietary effect on liver fatty acid synthetase.", "content": "Dietary effect on liver fatty acid synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196322"} {"pmid": "4196324", "title": "Osmotic opening of the blood-brain barrier in the monkey without associated neurological deficits.", "content": "Osmotic opening of the blood-brain barrier in the monkey without associated neurological deficits. Hypertonic urea or lactamide solutions osmotically open the blood-brain barrier in the monkey without producing gross neurological deficits if the blood supply to the brain is not compromised. The brain is perfused via the left lingual artery when the external and common carotid arteries are clamped temporarily. Hypertonic perfusion, which opens the barrier by opening tight junctions between cerebrovascular endothelial cells, can thus be used to study barrier function and brain pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196324"} {"pmid": "4196325", "title": "Gas-filled structures providing buoyancy in photosynthetic organisms.", "content": "Gas-filled structures providing buoyancy in photosynthetic organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196325"} {"pmid": "4196329", "title": "On the histogenesis of the cells in fracture callus. Electron microscopic autoradiographic observations in parabiotic rats and studies on labeled monocytes.", "content": "On the histogenesis of the cells in fracture callus. Electron microscopic autoradiographic observations in parabiotic rats and studies on labeled monocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196329"} {"pmid": "4196330", "title": "Catecholamine storage in liver metastases of a malignant carotid body tumour. A biochemical and morphological study.", "content": "Catecholamine storage in liver metastases of a malignant carotid body tumour. A biochemical and morphological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196330"} {"pmid": "4196332", "title": "Interactions between modified phage T4 particles and spheroplasts.", "content": "Interactions between modified phage T4 particles and spheroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196332"} {"pmid": "4196331", "title": "The development of TSH producing pituitary tumours in the mouse.", "content": "The development of TSH producing pituitary tumours in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196331"} {"pmid": "4196333", "title": "A method of central venous alimentation catheter placement for use in small infants.", "content": "A method of central venous alimentation catheter placement for use in small infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196333"} {"pmid": "4196334", "title": "Effect of nitrate, ammonia and nitrogen starvation on the regulation of nitrate reductase in Cyanidium caldarium.", "content": "Effect of nitrate, ammonia and nitrogen starvation on the regulation of nitrate reductase in Cyanidium caldarium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196334"} {"pmid": "4196335", "title": "A comparison of pre-operative and primary radiotherapy in the treatment of carcinoma of the hypopharynx.", "content": "A comparison of pre-operative and primary radiotherapy in the treatment of carcinoma of the hypopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196335"} {"pmid": "4196336", "title": "Thoracic enteric cysts and diverticulae.", "content": "Thoracic enteric cysts and diverticulae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196336"} {"pmid": "4196337", "title": "Massive haemorrhage in elephantiasis neurofibroma.", "content": "Massive haemorrhage in elephantiasis neurofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196337"} {"pmid": "4196338", "title": "Enzyme typing of malaria parasites.", "content": "Enzyme typing of malaria parasites. Analysis of various isolates of Plasmodium falciparum from East and West Africa and from South-east Asia showed that some of the parasite enzymes can exist in more than one electrophoretic form. At least one form of each enzyme was common to parasites from all three regions. The enzyme forms could be used to differentiate morphologically indistinguishable samples of P. falciparum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196338"} {"pmid": "4196340", "title": "Experimental infection of animals with influenzavirus types A and B.", "content": "Experimental infection of animals with influenzavirus types A and B. The knowledge that domestic cats were susceptible to infection with freshly isolated A/Hong Kong/68 influenzavirus led to studies on the susceptibility of some other animal species to this virus, as well as to studies on the ability of egg-passaged Hong Kong virus and an Asian virus to infect cats. The ability of a recent isolate of influenzavirus B to infect these animals was also studied. Macaca radiata monkeys could be infected with fresh isolates of A/Hong Kong virus by intranasal instillation or by contact with infected animals. They could also be infected with influenzavirus B by intranasal challenge, but contact transmission was not demonstrated. Mongrel dogs were found to be susceptible to A/Hong Kong/68 virus by intranasal instillation, but not to type B virus. Domestic cats could be infected with A/Hong Kong/68 virus passaged 6 times in eggs. They were also susceptible to infection with an established laboratory strain of Asian virus. Cats could be infected with influenzavirus B either by intranasal challenge or by contact with infected animals. In no case was clinical illness found following infection, but the infected animals shed virus from the throat and developed haemagglutination inhibiting antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196340"} {"pmid": "4196339", "title": "Anthrax.", "content": "Anthrax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196339"} {"pmid": "4196341", "title": "Temperature-dependent transition in L-histidine ammonia-lyase.", "content": "Temperature-dependent transition in L-histidine ammonia-lyase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196341"} {"pmid": "4196342", "title": "Fractionation of chromatin components.", "content": "Fractionation of chromatin components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196342"} {"pmid": "4196343", "title": "Various blood glucose values in the rat.", "content": "Various blood glucose values in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196343"} {"pmid": "4196344", "title": "Preparation of 125I-labelled thyrotrophin-releasing hormone.", "content": "Preparation of 125I-labelled thyrotrophin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196344"} {"pmid": "4196345", "title": "Falsely high fluorescence in cortisol determinations due to the carbamazepine.", "content": "Falsely high fluorescence in cortisol determinations due to the carbamazepine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196345"} {"pmid": "4196346", "title": "Different amounts of insulin secretion following an equal total decrease of blood glucose as an indication of possible extrapancreatic activities of different sulfonylurea drugs.", "content": "Different amounts of insulin secretion following an equal total decrease of blood glucose as an indication of possible extrapancreatic activities of different sulfonylurea drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196346"} {"pmid": "4196347", "title": "The microbiologic determination of serum folic acid activity. I. Study of the assay system.", "content": "The microbiologic determination of serum folic acid activity. I. Study of the assay system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196347"} {"pmid": "4196348", "title": "A trial of haemagglutination, circumoval precipitin and gel diffusion tests in hookworm infection.", "content": "A trial of haemagglutination, circumoval precipitin and gel diffusion tests in hookworm infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196348"} {"pmid": "4196349", "title": "Effect of cortisone on immunologic cardiac injury in albino rats.", "content": "Effect of cortisone on immunologic cardiac injury in albino rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196349"} {"pmid": "4196350", "title": "The immune response of a cyprinid fish to infections of the acanthocephalan Pomphorhynchus laevis.", "content": "The immune response of a cyprinid fish to infections of the acanthocephalan Pomphorhynchus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196350"} {"pmid": "4196351", "title": "Measurement of the infectivity of Trypanosoma cruzi in faeces of Rhodnius by comparison of dose-response curves.", "content": "Measurement of the infectivity of Trypanosoma cruzi in faeces of Rhodnius by comparison of dose-response curves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196351"} {"pmid": "4196355", "title": "United States-Japan cooperative drug abuse study.", "content": "United States-Japan cooperative drug abuse study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196355"} {"pmid": "4196356", "title": "Function of the alpha cell in diabetic ketoacidosis.", "content": "Function of the alpha cell in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196356"} {"pmid": "4196358", "title": "Auditory processing of biologically significant sounds.", "content": "Auditory processing of biologically significant sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196358"} {"pmid": "4196360", "title": "Effects of chlordiazepoxide upon successive red-green discrimination responses in Japanese monkeys, Macaca fuscata.", "content": "Effects of chlordiazepoxide upon successive red-green discrimination responses in Japanese monkeys, Macaca fuscata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196360"} {"pmid": "4196359", "title": "Fine structure of the chloroplast membranes of Euglena gracilis as revealed by freeze-cleaving and deep-etching techniques.", "content": "Fine structure of the chloroplast membranes of Euglena gracilis as revealed by freeze-cleaving and deep-etching techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196359"} {"pmid": "4196363", "title": "The handling of contaminated abdominal wounds.", "content": "The handling of contaminated abdominal wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196363"} {"pmid": "4196364", "title": "Ultrastructure and ion distribution of the intestinal cell during experimental vitamin-D deficiency rickets in rats.", "content": "Ultrastructure and ion distribution of the intestinal cell during experimental vitamin-D deficiency rickets in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196364"} {"pmid": "4196369", "title": "Fatal necrotizing angiitis after sulfadimethoxine therapy presenting as anaphylactoid purpura.", "content": "Fatal necrotizing angiitis after sulfadimethoxine therapy presenting as anaphylactoid purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196369"} {"pmid": "4196370", "title": "Regional variations in mouse skin: quantitation of epidermal compartments in two different body sites.", "content": "Regional variations in mouse skin: quantitation of epidermal compartments in two different body sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196370"} {"pmid": "4196374", "title": "Puzzling structures in the renal glomeruli of 13 patients. An electron microscopical study.", "content": "Puzzling structures in the renal glomeruli of 13 patients. An electron microscopical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196374"} {"pmid": "4196375", "title": "Procedures in radiation therapy dosimetry with 5 to 50 MeV electrons and roentgen and gamma rays with maximum photon energies between 1 and 50 MeV.", "content": "Procedures in radiation therapy dosimetry with 5 to 50 MeV electrons and roentgen and gamma rays with maximum photon energies between 1 and 50 MeV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196375"} {"pmid": "4196377", "title": "Genealogical mating activity in free-ranging groups of rhesus monkeys (Macaca mulatta) on Cayo Santiago.", "content": "Genealogical mating activity in free-ranging groups of rhesus monkeys (Macaca mulatta) on Cayo Santiago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196377"} {"pmid": "4196378", "title": "In vitro synthesis of DNA spontaneously released by bacteria or frog auricles.", "content": "In vitro synthesis of DNA spontaneously released by bacteria or frog auricles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196378"} {"pmid": "4196376", "title": "Electroanesthesia studies: cerebral blood flow and oxygen utilization during electroanesthesia in the rhesus.", "content": "Electroanesthesia studies: cerebral blood flow and oxygen utilization during electroanesthesia in the rhesus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196376"} {"pmid": "4196423", "title": "Ophthalmic care in Greenland.", "content": "Ophthalmic care in Greenland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196423"} {"pmid": "4196424", "title": "The ocular inflammation produced following intravitreal injection of a stable L-phase variant of Neisseria meningitidis.", "content": "The ocular inflammation produced following intravitreal injection of a stable L-phase variant of Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196424"} {"pmid": "4196425", "title": "Echovirus type 17 in the neonate.", "content": "Echovirus type 17 in the neonate. An outbreak of echovirus type 17 in a neonatal nursery with recovery of virus from the stools of the seven affected infants and the cerebrospinal fluid of one is described. Intensive nursing care and supportive therapy prevented a possible fatal outcome in all instances. A further case in another community is described in which a 5-week-old child succumbed to his illness and echovirus type 17 was isolated from autopsy tissues - lung, liver, kidney and spleen. This child had presumably received poor home care. The suggestion is made that while echovirus type 17 is not frequently associated with adult disease, it may exhibit affinity for infant tissues. This is thought to be the first time that this virus has been associated with clinical disease in a neonatal nursery and also the first account of its recovery from postmortem tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196425"} {"pmid": "4196426", "title": "Cytotoxic effect of dimethylsulfoxide on the ultrastructure of cultured Rhesus kidney cells.", "content": "Cytotoxic effect of dimethylsulfoxide on the ultrastructure of cultured Rhesus kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196426"} {"pmid": "4196427", "title": "Characteristics of the pituitary binding sites for thyrotropin releasing factor.", "content": "Characteristics of the pituitary binding sites for thyrotropin releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196427"} {"pmid": "4196429", "title": "Gonadal function and the biological and physicochemical properties of follicle stimulating hormone.", "content": "Gonadal function and the biological and physicochemical properties of follicle stimulating hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196429"} {"pmid": "4196428", "title": "Radioimmunoassay of rhesus monkey follicle stimulating hormone (RhFSH).", "content": "Radioimmunoassay of rhesus monkey follicle stimulating hormone (RhFSH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196428"} {"pmid": "4196430", "title": "Hyperthyroidism induced by thyrotropin-releasing hormone in mice.", "content": "Hyperthyroidism induced by thyrotropin-releasing hormone in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196430"} {"pmid": "4196431", "title": "Induced LH surges in the rhesus monkey: strength-duration characteristics of the estrogen stimulus.", "content": "Induced LH surges in the rhesus monkey: strength-duration characteristics of the estrogen stimulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196431"} {"pmid": "4196432", "title": "Grading of protein calorie malnutrition.", "content": "Grading of protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196432"} {"pmid": "4196433", "title": "The kinetics of the killing of mouse tumour cells in vivo by immune responses.", "content": "The kinetics of the killing of mouse tumour cells in vivo by immune responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196433"} {"pmid": "4196434", "title": "Genetic properties of substituted derivatives of N-methyl-4-aminoazobenzene in relation to azo-dye carcinogenesis.", "content": "Genetic properties of substituted derivatives of N-methyl-4-aminoazobenzene in relation to azo-dye carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196434"} {"pmid": "4196436", "title": "Cellular immunity to human urinary bladder carcinoma. I. Correlation to clinical stage and radiotherapy.", "content": "Cellular immunity to human urinary bladder carcinoma. I. Correlation to clinical stage and radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196436"} {"pmid": "4196437", "title": "Cellular immunity to human urinary bladder carcinoma. II. EEffect of surgery and preoperative irradiation.", "content": "Cellular immunity to human urinary bladder carcinoma. II. EEffect of surgery and preoperative irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196437"} {"pmid": "4196438", "title": "Induction of delayed-type sensitivity-like reactions in the eye by the injection of lymphokines.", "content": "Induction of delayed-type sensitivity-like reactions in the eye by the injection of lymphokines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196438"} {"pmid": "4196439", "title": "Prostaglandin synthesis, inhibition, and intraocular pressure.", "content": "Prostaglandin synthesis, inhibition, and intraocular pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196439"} {"pmid": "4196440", "title": "The effect of arterial PCO2 on inner-retinal oxygen availability in monkeys.", "content": "The effect of arterial PCO2 on inner-retinal oxygen availability in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196440"} {"pmid": "4196441", "title": "The effect of arterial PCO2 on inner-retinal oxygen consumption rate in monkeys.", "content": "The effect of arterial PCO2 on inner-retinal oxygen consumption rate in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196441"} {"pmid": "4196443", "title": "Treatment of defects of the ulna in children by establishing cross-union with the radius.", "content": "Treatment of defects of the ulna in children by establishing cross-union with the radius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196443"} {"pmid": "4196442", "title": "Dome fracture of the talus. A report of ten cases.", "content": "Dome fracture of the talus. A report of ten cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196442"} {"pmid": "4196445", "title": "Activity of aminoglycoside antibiotics aganst Pseudomonas aeruginosa: specificity and site of calcium and magnesium antagonism.", "content": "Activity of aminoglycoside antibiotics aganst Pseudomonas aeruginosa: specificity and site of calcium and magnesium antagonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196445"} {"pmid": "4196446", "title": "Immunology of Escherichia coli: K antigen and its relation to urinary-tract infection.", "content": "Immunology of Escherichia coli: K antigen and its relation to urinary-tract infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196446"} {"pmid": "4196447", "title": "Comparative activity of sisomicin against mycobacteria in vitro and against Mycobacterium tuberculosis in mice.", "content": "Comparative activity of sisomicin against mycobacteria in vitro and against Mycobacterium tuberculosis in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196447"} {"pmid": "4196449", "title": "Fetal-maternal plasma calcium relationships in rat and sheep.", "content": "Fetal-maternal plasma calcium relationships in rat and sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196449"} {"pmid": "4196451", "title": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamá and Colombia. I. Introduction.", "content": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamá and Colombia. I. Introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196451"} {"pmid": "4196452", "title": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamá and Colombia. II. geography of proposed routes.", "content": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamá and Colombia. II. geography of proposed routes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196452"} {"pmid": "4196453", "title": "Problems in interpreting tuberculin skin tests. When is a converter not a converter?: a review.", "content": "Problems in interpreting tuberculin skin tests. When is a converter not a converter?: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196453"} {"pmid": "4196454", "title": "Pyrimethamine-induced leukopenia and thrombocytopenia in a patient with malaria and tropical sprue: case report.", "content": "Pyrimethamine-induced leukopenia and thrombocytopenia in a patient with malaria and tropical sprue: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196454"} {"pmid": "4196456", "title": "Building a new wing.", "content": "Building a new wing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196456"} {"pmid": "4196455", "title": "Case for diagnosis: focal interstitial myocarditis.", "content": "Case for diagnosis: focal interstitial myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196455"} {"pmid": "4196457", "title": "The development of a MHCS role in race relations.", "content": "The development of a MHCS role in race relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196457"} {"pmid": "4196458", "title": "Mental hygiene command consultation program at an army training center.", "content": "Mental hygiene command consultation program at an army training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196458"} {"pmid": "4196459", "title": "Experience with drug abuse.", "content": "Experience with drug abuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196459"} {"pmid": "4196460", "title": "A clinical evaluation of 81 heroin addicts in Vietnam.", "content": "A clinical evaluation of 81 heroin addicts in Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196460"} {"pmid": "4196461", "title": "Neuroepidemiology.", "content": "Neuroepidemiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196461"} {"pmid": "4196462", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196462"} {"pmid": "4196463", "title": "Effects of testosterone treatment in adulthood on sexual behaviour of female pseudohermaphrodite rhesus monkeys.", "content": "Effects of testosterone treatment in adulthood on sexual behaviour of female pseudohermaphrodite rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196463"} {"pmid": "4196464", "title": "Validity of the quadratic fitness function.", "content": "Validity of the quadratic fitness function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196464"} {"pmid": "4196466", "title": "Complications of total hip replacement arthroplasty.", "content": "Complications of total hip replacement arthroplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196466"} {"pmid": "4196465", "title": "Early results of Charnley-Müller total hip reconstruction.", "content": "Early results of Charnley-Müller total hip reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196465"} {"pmid": "4196467", "title": "The Amsel frustration effect: interpretations and research.", "content": "The Amsel frustration effect: interpretations and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196467"} {"pmid": "4196472", "title": "Enhanced emigration of crevicular leukocytes mediated by factors in human dental plaque.", "content": "Enhanced emigration of crevicular leukocytes mediated by factors in human dental plaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196472"} {"pmid": "4196471", "title": "Observations on endopeptidases in human carious dentin.", "content": "Observations on endopeptidases in human carious dentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196471"} {"pmid": "4196473", "title": "Respiratory disease and ABO and rhesus blood groups.", "content": "Respiratory disease and ABO and rhesus blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196473"} {"pmid": "4196474", "title": "Long term maintenance of Theileria annulata strains by freezing at -70 degrees C.", "content": "Long term maintenance of Theileria annulata strains by freezing at -70 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196474"} {"pmid": "4196476", "title": "Hemophilia B in a phenotypically normal girl with XX (ring) XO mosaicism.", "content": "Hemophilia B in a phenotypically normal girl with XX (ring) XO mosaicism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196476"} {"pmid": "4196477", "title": "Abnormal factor X(factor X Friuli) coagulation disorder.", "content": "Abnormal factor X(factor X Friuli) coagulation disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196477"} {"pmid": "4196478", "title": "Hypofibrinogenemia after Echis colorata bite in man.", "content": "Hypofibrinogenemia after Echis colorata bite in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196478"} {"pmid": "4196480", "title": "Heinz body susceptibility of red cells and exchange transfusion.", "content": "Heinz body susceptibility of red cells and exchange transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196480"} {"pmid": "4196479", "title": "Factors influencing the uptake of vitamin B 12 by normoblastic and vitamin B 12 -deficient bone marrow cells.", "content": "Factors influencing the uptake of vitamin B 12 by normoblastic and vitamin B 12 -deficient bone marrow cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196479"} {"pmid": "4196481", "title": "The fibrinolytic enzyme system in malignant lymphomas.", "content": "The fibrinolytic enzyme system in malignant lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196481"} {"pmid": "4196483", "title": "Whole-body autoradiography of 1-tetrahydrocannabinol and 1(6)-tetrahydrocannabinol in mouse. Pharmacokinetic aspects of 1-tetrahydrocannabinol and its metabolites.", "content": "Whole-body autoradiography of 1-tetrahydrocannabinol and 1(6)-tetrahydrocannabinol in mouse. Pharmacokinetic aspects of 1-tetrahydrocannabinol and its metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196483"} {"pmid": "4196484", "title": "Factors influencing the secretion of human prolactin and growth hormone in menstrual and gestational women.", "content": "Factors influencing the secretion of human prolactin and growth hormone in menstrual and gestational women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196484"} {"pmid": "4196485", "title": "Porcine coronaviruses: co-infection of cell cultures with transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus.", "content": "Porcine coronaviruses: co-infection of cell cultures with transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196485"} {"pmid": "4196487", "title": "Heteroxanthin in Euglena gracilis.", "content": "Heteroxanthin in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196487"} {"pmid": "4196488", "title": "Action of lysozyme on Anabaena ambigua Rao.", "content": "Action of lysozyme on Anabaena ambigua Rao.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196488"} {"pmid": "4196490", "title": "Isolation of and production of antibody to cow chromaffin granule membrane.", "content": "Isolation of and production of antibody to cow chromaffin granule membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196490"} {"pmid": "4196491", "title": "Membranes of Tetrahymena. 3. The effect of temperature on membrane core structures and fatty acid composition of Tetrahymena cells.", "content": "Membranes of Tetrahymena. 3. The effect of temperature on membrane core structures and fatty acid composition of Tetrahymena cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196491"} {"pmid": "4196492", "title": "An ultrastructural study of the red pulp of the spleen in malaria.", "content": "An ultrastructural study of the red pulp of the spleen in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196492"} {"pmid": "4196493", "title": "Occlusion of the vortex veins. An experimental study.", "content": "Occlusion of the vortex veins. An experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196493"} {"pmid": "4196526", "title": "The Cancer Control Program of the National Cancer Institute.", "content": "The Cancer Control Program of the National Cancer Institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196526"} {"pmid": "4196535", "title": "A comparison of different compounds for TBG-blocking used in radioimmunoassay for tri-iodothyronine.", "content": "A comparison of different compounds for TBG-blocking used in radioimmunoassay for tri-iodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196535"} {"pmid": "4196527", "title": "Unproven methods of cancer management. Krebiozen and carcalon.", "content": "Unproven methods of cancer management. Krebiozen and carcalon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196527"} {"pmid": "4196537", "title": "A new extrapigmentary effect of alpha-MSH. Promotion of sodium uptake in the heart of toads and rats.", "content": "A new extrapigmentary effect of alpha-MSH. Promotion of sodium uptake in the heart of toads and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196537"} {"pmid": "4196528", "title": "Cookbook cancer therapy.", "content": "Cookbook cancer therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196528"} {"pmid": "4196538", "title": "A study of immunoglobulins in protein calorie malnutrition.", "content": "A study of immunoglobulins in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196538"} {"pmid": "4196539", "title": "Immunoglobulins and C 3 levels in normal Indians: details of methodology, standardization, variation and statistical methods.", "content": "Immunoglobulins and C 3 levels in normal Indians: details of methodology, standardization, variation and statistical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196539"} {"pmid": "4196540", "title": "A new simplified sugar medium for fermentation test with plague, pseudotuberculosis and diphtheria organisms.", "content": "A new simplified sugar medium for fermentation test with plague, pseudotuberculosis and diphtheria organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196540"} {"pmid": "4196531", "title": "Colorectal polyps.", "content": "Colorectal polyps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196531"} {"pmid": "4196530", "title": "Rx of bladder cancer: complex and controversial.", "content": "Rx of bladder cancer: complex and controversial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196530"} {"pmid": "4196541", "title": "Viability of N. gonorrhoeae in transport media.", "content": "Viability of N. gonorrhoeae in transport media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196541"} {"pmid": "4196534", "title": "An approach to the control of carcinoma of the endometrium.", "content": "An approach to the control of carcinoma of the endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196534"} {"pmid": "4196533", "title": "The treatment of wounds with special reference to the value of the blood clot in the management of dead space. IV. Operations for carcinoma of the breast by William S. Halsted, M.D., reprinted from Johns Hopkins Hospital Reports, Vol. II, No. 5, 277-280, 1891.", "content": "The treatment of wounds with special reference to the value of the blood clot in the management of dead space. IV. Operations for carcinoma of the breast by William S. Halsted, M.D., reprinted from Johns Hopkins Hospital Reports, Vol. II, No. 5, 277-280, 1891.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196533"} {"pmid": "4196529", "title": "Vaccine trials for osteogenic sarcoma. A preliminary report.", "content": "Vaccine trials for osteogenic sarcoma. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196529"} {"pmid": "4196543", "title": "Peripheral ossifying fibroma: report of case.", "content": "Peripheral ossifying fibroma: report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196543"} {"pmid": "4196544", "title": "Preservation and biodegradation of the morphogenetic property of bone matrix.", "content": "Preservation and biodegradation of the morphogenetic property of bone matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196544"} {"pmid": "4196547", "title": "\"Rynacrom\" (sodium cromoglycate).", "content": "\"Rynacrom\" (sodium cromoglycate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196547"} {"pmid": "4196532", "title": "William Stewart Halsted (1852-1922).", "content": "William Stewart Halsted (1852-1922).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196532"} {"pmid": "4196551", "title": "Inpatient surgery on an ambulatory basis.", "content": "Inpatient surgery on an ambulatory basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196551"} {"pmid": "4196554", "title": "Serum concentrations of ampicillin in newborn infants after oral administration.", "content": "Serum concentrations of ampicillin in newborn infants after oral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196554"} {"pmid": "4196553", "title": "Protein calorie malnutrition and infection with hepatitis-associated antigen.", "content": "Protein calorie malnutrition and infection with hepatitis-associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196553"} {"pmid": "4196555", "title": "Hyperammonemia: another hazard in parenteral alimentation.", "content": "Hyperammonemia: another hazard in parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196555"} {"pmid": "4196556", "title": "Nasogastric tube feedings. Practical considerations in prescription and evaluation.", "content": "Nasogastric tube feedings. Practical considerations in prescription and evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196556"} {"pmid": "4196557", "title": "Nutritional care after head and neck surgery.", "content": "Nutritional care after head and neck surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196557"} {"pmid": "4196558", "title": "Changing concepts in prenatal care.", "content": "Changing concepts in prenatal care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196558"} {"pmid": "4196559", "title": "Virus-like particles in natural scrapie of the sheep.", "content": "Virus-like particles in natural scrapie of the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196559"} {"pmid": "4196560", "title": "The use of fluorescent antibody technqiues to detect Theileria parva in the salivary glands of the tick Rhipicephalus appendicalatus.", "content": "The use of fluorescent antibody technqiues to detect Theileria parva in the salivary glands of the tick Rhipicephalus appendicalatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196560"} {"pmid": "4196561", "title": "Observations on the haematology of experimentally induced Babesia argentina and B. bigemina infections in splenectomised calves.", "content": "Observations on the haematology of experimentally induced Babesia argentina and B. bigemina infections in splenectomised calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196561"} {"pmid": "4196562", "title": "Haemoglobin reactive protein in cattle: partial characterisation.", "content": "Haemoglobin reactive protein in cattle: partial characterisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196562"} {"pmid": "4196563", "title": "Chemical and microbial degradation of ten selected pesticides in aquatic systems.", "content": "Chemical and microbial degradation of ten selected pesticides in aquatic systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196563"} {"pmid": "4196567", "title": "Laboratory experiments with uropathogenic bacteria and chlorhexidine.", "content": "Laboratory experiments with uropathogenic bacteria and chlorhexidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196567"} {"pmid": "4196568", "title": "Metabolism of radioactive-labeled fat emulsions in the postoperative and posttraumatic period.", "content": "Metabolism of radioactive-labeled fat emulsions in the postoperative and posttraumatic period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196568"} {"pmid": "4196569", "title": "Vitamin B 12 absorption in protein-calorie malnourished children and during recovery: influence of protein depletion and of diarrhea.", "content": "Vitamin B 12 absorption in protein-calorie malnourished children and during recovery: influence of protein depletion and of diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196569"} {"pmid": "4196570", "title": "Malnutrition studies in Macaca mulatta. II. The effect on organ size and skeletal growth.", "content": "Malnutrition studies in Macaca mulatta. II. The effect on organ size and skeletal growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196570"} {"pmid": "4196572", "title": "Communication among primates.", "content": "Communication among primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196572"} {"pmid": "4196573", "title": "Heart: excitation-contraction coupling.", "content": "Heart: excitation-contraction coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196573"} {"pmid": "4196574", "title": "Normal tissue tolerance to particle and heavy ion radiation.", "content": "Normal tissue tolerance to particle and heavy ion radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196574"} {"pmid": "4196578", "title": "The DNA of Tetrahymena pyriformis GL strain. A mild method for preparation and its characterization.", "content": "The DNA of Tetrahymena pyriformis GL strain. A mild method for preparation and its characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196578"} {"pmid": "4196579", "title": "Immunologic studies on intracellular isoenzymes; the mitochondrial and cytoplasmic leucyl-tRNA synthetases.", "content": "Immunologic studies on intracellular isoenzymes; the mitochondrial and cytoplasmic leucyl-tRNA synthetases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196579"} {"pmid": "4196571", "title": "Value of immunodiffusion tests in the diagnosis of systemic mycotic diseases.", "content": "Value of immunodiffusion tests in the diagnosis of systemic mycotic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196571"} {"pmid": "4196581", "title": "A comparison of effective thyroxine ratio and free thyroxine in serum.", "content": "A comparison of effective thyroxine ratio and free thyroxine in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196581"} {"pmid": "4196580", "title": "The specific immunoprecipitation of polyribosomes synthesizing an immunoglobulin light chain.", "content": "The specific immunoprecipitation of polyribosomes synthesizing an immunoglobulin light chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196580"} {"pmid": "4196584", "title": "Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin.", "content": "Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196584"} {"pmid": "4196583", "title": "The mechanism of the antihypertensive action of -methyldopa in hypertensive rats.", "content": "The mechanism of the antihypertensive action of -methyldopa in hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196583"} {"pmid": "4196575", "title": "Lymphocyte heterogeneity and function.", "content": "Lymphocyte heterogeneity and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196575"} {"pmid": "4196585", "title": "Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins.", "content": "Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196585"} {"pmid": "4196586", "title": "Diphtheria toxin and related proteins. 3. Reconstitution of hybrid \"diphtheria toxin\" from nontoxic mutant proteins.", "content": "Diphtheria toxin and related proteins. 3. Reconstitution of hybrid \"diphtheria toxin\" from nontoxic mutant proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196586"} {"pmid": "4196587", "title": "Magnetic circular dichroism of cobalt-copper and zinc-copper bovine superoxide dismutase.", "content": "Magnetic circular dichroism of cobalt-copper and zinc-copper bovine superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196587"} {"pmid": "4196588", "title": "Transport of vitamin B 12 in Escherichia coli. Location and properties of the initial B 12 -binding site.", "content": "Transport of vitamin B 12 in Escherichia coli. Location and properties of the initial B 12 -binding site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196588"} {"pmid": "4196590", "title": "Combination of specific antibodies with the human vitamin A-transporting protein complex.", "content": "Combination of specific antibodies with the human vitamin A-transporting protein complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196590"} {"pmid": "4196591", "title": "Aspergillus fumigatus in samples of moldy silage.", "content": "Aspergillus fumigatus in samples of moldy silage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196591"} {"pmid": "4196589", "title": "Oxidation of catechol in plants. IV. Purification and properties of the 3,4,3',4'-tetrahydroxydiphenyl-forming enzyme system from Tecoma leaves.", "content": "Oxidation of catechol in plants. IV. Purification and properties of the 3,4,3',4'-tetrahydroxydiphenyl-forming enzyme system from Tecoma leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196589"} {"pmid": "4196592", "title": "Basal body addition in ciliary rows of Tetrahymena pyriformis.", "content": "Basal body addition in ciliary rows of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196592"} {"pmid": "4196594", "title": "Tyrosine and catecholamine metabolism in wild-type Drosophila melanogaster and a mutant, ebony.", "content": "Tyrosine and catecholamine metabolism in wild-type Drosophila melanogaster and a mutant, ebony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196594"} {"pmid": "4196595", "title": "Radiologic seminar CXXVII: jejunal diverticulosis.", "content": "Radiologic seminar CXXVII: jejunal diverticulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196595"} {"pmid": "4196599", "title": "Lithium fluoride: an inexpensive calibration check for the general hospital.", "content": "Lithium fluoride: an inexpensive calibration check for the general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196599"} {"pmid": "4196600", "title": "The value of lumbar spinal tap in the diagnosis of closed head injury.", "content": "The value of lumbar spinal tap in the diagnosis of closed head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196600"} {"pmid": "4196603", "title": "WHO Expert Committee on Rabies: sixth report.", "content": "WHO Expert Committee on Rabies: sixth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196603"} {"pmid": "4196604", "title": "Pharmacogenetics. Report of a WHO scientific group.", "content": "Pharmacogenetics. Report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196604"} {"pmid": "4196605", "title": "Reye syndrome. 3. The hypoglycemia.", "content": "Reye syndrome. 3. The hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196605"} {"pmid": "4196597", "title": "Megavoltage port radiography for therapy evaluation.", "content": "Megavoltage port radiography for therapy evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196597"} {"pmid": "4196606", "title": "Infantile cirrhosis with hereditary alpha 1 -antitrypsin deficiency. Clinical improvement in two siblings.", "content": "Infantile cirrhosis with hereditary alpha 1 -antitrypsin deficiency. Clinical improvement in two siblings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196606"} {"pmid": "4196607", "title": "Tuberculosis of the skin.", "content": "Tuberculosis of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196607"} {"pmid": "4196596", "title": "Planning for dialysis and transplantation facilities.", "content": "Planning for dialysis and transplantation facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196596"} {"pmid": "4196628", "title": "The visual component in the courtship of Drosophila melanogaster.", "content": "The visual component in the courtship of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196628"} {"pmid": "4196627", "title": "Disappearance of radioactivity from plasma following intravenous administration of tritiated thyrotrophin-releasing hormone (Ro 8-6270) to man.", "content": "Disappearance of radioactivity from plasma following intravenous administration of tritiated thyrotrophin-releasing hormone (Ro 8-6270) to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196627"} {"pmid": "4196630", "title": "The ingestion of gonococci by epithelial cells.", "content": "The ingestion of gonococci by epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196630"} {"pmid": "4196631", "title": "Attachment of gonococci to the urethral mucosal cells of patients with gonorrhoea--a critical early stage in the pathogenesis of the infection?", "content": "Attachment of gonococci to the urethral mucosal cells of patients with gonorrhoea--a critical early stage in the pathogenesis of the infection?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196631"} {"pmid": "4196629", "title": "The lipolytic activity of Micrococcaceae from human and animal sources.", "content": "The lipolytic activity of Micrococcaceae from human and animal sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196629"} {"pmid": "4196632", "title": "Raised intracranial pressure and cerebral blood flow. 2. Supratentorial and infratentorial mass lesions in primates.", "content": "Raised intracranial pressure and cerebral blood flow. 2. Supratentorial and infratentorial mass lesions in primates. Changes in cerebral blood flow with increasing intracranial pressure were studied in anaesthetized baboons during expansion of a subdural balloon in one of two different sites. With an infratentorial balloon, cerebral blood flow bore no clear relation to intracranial pressure, but was linearly related to cerebral perfusion pressure. Apart from an initial change in some animals, cerebrovascular resistance remained constant with increasing intracranial pressure, and autoregulation appeared to be lost from the outset. With a supratentorial balloon, cerebral blood flow remained constant as intracranial pressure was increased to levels around 60 mm Hg, corresponding to a cerebral perfusion pressure range of approximately 100 to 40 mmHg. Cerebrovascular resistance fell progressively, and autoregulation appeared to be effective during this phase. At higher intracranial pressure levels (lower cerebral perfusion pressure levels), autoregulation was lost and cerebral blood flow became directly dependent on cerebral perfusion pressure. The importance of the cause of the increase in intracranial pressure on the response of the cerebral circulation and the relevance of these findings to the clinical situation are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196632"} {"pmid": "4196633", "title": "Outgrowth of Bacillus cereus spores harboring bacteriophage CP-51 DNA. I. Initiation of bacteriophage development.", "content": "Outgrowth of Bacillus cereus spores harboring bacteriophage CP-51 DNA. I. Initiation of bacteriophage development. Time of initiation of bacteriophage CP-51 RNA synthesis, inhibition of host DNA synthesis, initiation of CP-51 DNA synthesis, and release of phage was determined in infected Bacillus cereus cells and outgrowing spores harboring phage DNA. The development of phage in outgrowing spores is initiated 45 min after induction of spore germination and then proceeds at a rate similar to that observed in infected cells. Although spore RNA synthesis is inhibited by the presence of chloramphenicol or puromycin during germination, these antibiotics do not inhibit initiation of phage DNA transcription in outgrowing spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196633"} {"pmid": "4196635", "title": "Genetic study of suppressor-sensitive mutants of the Bacillus subtilis bacteriophage phi 29.", "content": "Genetic study of suppressor-sensitive mutants of the Bacillus subtilis bacteriophage phi 29. With bacteriophage phi29 of Bacillus subtilis 133, suppressor-sensitive (sus) hydroxylamine mutants have been isolated. Intracistronic and intercistronic quantitative complementation placed the mutants in 13 cistrons, and three-factor crosses have been used to assign an unambiguous order for 10 cistrons. Recombination frequencies have been presented for several regions of the genome to facilitate comparison of the sus system with the previously published temperature-sensitive mapping systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196635"} {"pmid": "4196634", "title": "Rabies group-specific ribonucleoprotein antigen and a test system for grouping and typing of rhabdoviruses.", "content": "Rabies group-specific ribonucleoprotein antigen and a test system for grouping and typing of rhabdoviruses. Cell-associated ribonucleoprotein (RNP) was isolated from BHK-21 cells infected with several strains of rabies and rabies-related viruses. The RNP-antigen from rabies and related viruses induced the formation of complement-fixing, precipitating, and immunofluorescent antibodies, and proved to be the group-specific antigen common to all rabies viruses. Antigens of the envelope which induce virus-neutralizing antibodies are apparently determinative for the serotype of a virus as evidenced by two-way neutralization tests. A combination of these methods seems to be a useful approach to the serological grouping and typing of rhabdoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196634"} {"pmid": "4196640", "title": "Protein differences associated with a phototransduction mutant of Drosophila.", "content": "Protein differences associated with a phototransduction mutant of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196640"} {"pmid": "4196641", "title": "Phencyclidine action on neural mechanisms of somesthesis.", "content": "Phencyclidine action on neural mechanisms of somesthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196641"} {"pmid": "4196643", "title": "Daily fetal movement recording and fetal prognosis.", "content": "Daily fetal movement recording and fetal prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196643"} {"pmid": "4196642", "title": "Lecithin-sphingomyelin ratio and a rapid test for surfactant in amniotic fluid. A comparison.", "content": "Lecithin-sphingomyelin ratio and a rapid test for surfactant in amniotic fluid. A comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196642"} {"pmid": "4196644", "title": "Interocular transfer of reversed and nonreversed discrimination via the anterior commissure in monkeys.", "content": "Interocular transfer of reversed and nonreversed discrimination via the anterior commissure in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196644"} {"pmid": "4196645", "title": "Sexual behaviour of White Leghorn cocks bearing basal hypothalamic lesions in various locations.", "content": "Sexual behaviour of White Leghorn cocks bearing basal hypothalamic lesions in various locations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196645"} {"pmid": "4196647", "title": "A method for the construction and use of contact occluders for small animals.", "content": "A method for the construction and use of contact occluders for small animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196647"} {"pmid": "4196646", "title": "Peripheral and central stimulus detection in auditory pathways of monkeys.", "content": "Peripheral and central stimulus detection in auditory pathways of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196646"} {"pmid": "4196649", "title": "Diabetic keto-acidosis complicated by disseminated intravascular coagulation.", "content": "Diabetic keto-acidosis complicated by disseminated intravascular coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196649"} {"pmid": "4196650", "title": "Gonococcal arthritis in pregnancy.", "content": "Gonococcal arthritis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196650"} {"pmid": "4196651", "title": "Anorectal gonorrhea presenting as ulcerative proctitis.", "content": "Anorectal gonorrhea presenting as ulcerative proctitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196651"} {"pmid": "4196652", "title": "Colonization of burns by Streptococcus faecalis related to contaminated porcine xenografts.", "content": "Colonization of burns by Streptococcus faecalis related to contaminated porcine xenografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196652"} {"pmid": "4196655", "title": "Massive extracranial hematomas in two squirrel monkeys.", "content": "Massive extracranial hematomas in two squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196655"} {"pmid": "4196657", "title": "Canine alimentary neoplasia.", "content": "Canine alimentary neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196657"} {"pmid": "4196664", "title": "On the pharmacodynamics of Benzatcin.", "content": "On the pharmacodynamics of Benzatcin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196664"} {"pmid": "4196665", "title": "Tremor in diving.", "content": "Tremor in diving.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196665"} {"pmid": "4196666", "title": "Effect of various microorganisms found in cosmetics on the normal and injured eye of the rabbit.", "content": "Effect of various microorganisms found in cosmetics on the normal and injured eye of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196666"} {"pmid": "4196668", "title": "Conjunctivitis associated with Coxsackie B-1 virus in a laboratory worker.", "content": "Conjunctivitis associated with Coxsackie B-1 virus in a laboratory worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196668"} {"pmid": "4196667", "title": "Ocular and central nervous system findings in tetraploid-diploid mosaicism.", "content": "Ocular and central nervous system findings in tetraploid-diploid mosaicism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196667"} {"pmid": "4196669", "title": "Repair after xenon arc photocoagulation. 3. An electron microscopic study of the evolution of retinal lesions in rhesus monkeys.", "content": "Repair after xenon arc photocoagulation. 3. An electron microscopic study of the evolution of retinal lesions in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196669"} {"pmid": "4196672", "title": "The phenogenetics of a super-suppressor in Drosophila melanogaster. II. Suppression and back-mutation.", "content": "The phenogenetics of a super-suppressor in Drosophila melanogaster. II. Suppression and back-mutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196672"} {"pmid": "4196670", "title": "Severe problems with gastric emptying after gastric surgery.", "content": "Severe problems with gastric emptying after gastric surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196670"} {"pmid": "4196673", "title": "Deep freezing of boar semen. I. Effects of diluent composition, protective agents, and method of thawing on survival of spermatozoa.", "content": "Deep freezing of boar semen. I. Effects of diluent composition, protective agents, and method of thawing on survival of spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196673"} {"pmid": "4196674", "title": "Radioisotope-survey of metastases of breast carcinoma to bone using Sr-87m and whole body scanner.", "content": "Radioisotope-survey of metastases of breast carcinoma to bone using Sr-87m and whole body scanner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196674"} {"pmid": "4196675", "title": "An exo- -N-acetylglucosaminidase from Bacillus subtilis B; characterization.", "content": "An exo- -N-acetylglucosaminidase from Bacillus subtilis B; characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196675"} {"pmid": "4196676", "title": "Kinetic properties of microsomal UDP-glucuronyltransferase. Evidence for cooperative kinetics and activation by UDP-N-acetylglucosamine.", "content": "Kinetic properties of microsomal UDP-glucuronyltransferase. Evidence for cooperative kinetics and activation by UDP-N-acetylglucosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196676"} {"pmid": "4196677", "title": "Differentiation of homologous forms of hepatic microsomal UDP-glucuronyltransferase. I. Evidence for the glucuronidation of o-aminophenol and p-nitrophenol by separate enzymes.", "content": "Differentiation of homologous forms of hepatic microsomal UDP-glucuronyltransferase. I. Evidence for the glucuronidation of o-aminophenol and p-nitrophenol by separate enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196677"} {"pmid": "4196678", "title": "Differentiation of homologous forms of hepatic microsomal UDP-glucuronyltransferase. II. Characterization of the bilirubin conjugating form.", "content": "Differentiation of homologous forms of hepatic microsomal UDP-glucuronyltransferase. II. Characterization of the bilirubin conjugating form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196678"} {"pmid": "4196680", "title": "Adrenergic mechanism in Tetrahymena. I. Changes in monoamine oxidase activity during growth.", "content": "Adrenergic mechanism in Tetrahymena. I. Changes in monoamine oxidase activity during growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196680"} {"pmid": "4196681", "title": "Storage of insecticides in the fat body of Spodoptera littoralis (Boisd.) as a possible mechanism of resistance.", "content": "Storage of insecticides in the fat body of Spodoptera littoralis (Boisd.) as a possible mechanism of resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196681"} {"pmid": "4196683", "title": "Resistance to carbon dioxide, an anoxic stress in Drosophila melanogaster.", "content": "Resistance to carbon dioxide, an anoxic stress in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196683"} {"pmid": "4196684", "title": "A study of the differentiation of bracts in Drosophila melanogaster using two mutations, H 2 and sv de .", "content": "A study of the differentiation of bracts in Drosophila melanogaster using two mutations, H 2 and sv de .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196684"} {"pmid": "4196682", "title": "Intracellular response by Tetrahymena pyriformis to fluids from unimmunized animals.", "content": "Intracellular response by Tetrahymena pyriformis to fluids from unimmunized animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196682"} {"pmid": "4196687", "title": "Mechanical factors in the design of chronic recording intracortical microelectrodes.", "content": "Mechanical factors in the design of chronic recording intracortical microelectrodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196687"} {"pmid": "4196688", "title": "Immunochemical studies of two human liver carboxyl esterases.", "content": "Immunochemical studies of two human liver carboxyl esterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196688"} {"pmid": "4196689", "title": "The filtration coefficient of the intraocular vasculature as measured by low-pressure perfusion in a primate eye.", "content": "The filtration coefficient of the intraocular vasculature as measured by low-pressure perfusion in a primate eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196689"} {"pmid": "4196690", "title": "The effect of arterial PCO 2 on relative retinal blood flow in monkeys.", "content": "The effect of arterial PCO 2 on relative retinal blood flow in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196690"} {"pmid": "4196691", "title": "The intercellular junctional complexes of retinal pigment epithelia.", "content": "The intercellular junctional complexes of retinal pigment epithelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196691"} {"pmid": "4196692", "title": "Effect of exogenous interferon on herpetic keratitis in rabbits and monkeys.", "content": "Effect of exogenous interferon on herpetic keratitis in rabbits and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196692"} {"pmid": "4196694", "title": "Gel filtration of thyroxine-binding proteins. Identification of rat plasma protein fractions separated on sephadex G-200.", "content": "Gel filtration of thyroxine-binding proteins. Identification of rat plasma protein fractions separated on sephadex G-200.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196694"} {"pmid": "4196696", "title": "Disodium cromoglycate.", "content": "Disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196696"} {"pmid": "4196695", "title": "Separation of NTA and EDTA chelates by thin-layer chromatography.", "content": "Separation of NTA and EDTA chelates by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196695"} {"pmid": "4196699", "title": "The hypothermic effect of tetrodotoxin in the unanaesthetized cat.", "content": "The hypothermic effect of tetrodotoxin in the unanaesthetized cat. 1. The hypothermic effect on unanaesthetized cats of tetrodotoxin injected I.V. or into the lateral cerebral ventricle was examined.2. At an ambient temperature (T(a)) of 22 degrees C, tetrodotoxin given intraventricularly was over 400 times more potent in lowering body temperature (T(b)) than when given I.V. The magnitude of the hypothermia was dose-dependent for both routes. Decreases in T(b) as great as 6.8 degrees C were induced by infusions or multiple injections of tetrodotoxin into the ventricle.3. Tetrodotoxin also lowered T(b) at T(a) = 13, 30 or 35 degrees C. Tachypnoea, which lasted for longer durations and which became more intense the higher the T(a), accompanied development of hypothermia. Shivering was observed only during recovery from hypothermia at 13 degrees C.4. During the tetrodotoxin-induced hypothermia, animals were still able to regulate against environmental thermal stresses.5. EDTA disodium salt, leucocytic pyrogen and prostaglandin E(1) antagonized the hypothermic effect of tetrodotoxin when they were administered during recovery from tetrodotoxin.6. Activation of heat-loss mechanisms, and the absence of compensatory shivering during development of hypothermia after tetrodotoxin administration, plus lowering of T(b) by tetrodotoxin at T(a) above as well as below the thermoneutral temperature, indicate that lowering of the thermoregulatory set-point is the mechanism by which centrally or peripherally administered tetrodotoxin lowers T(b). Further evidence for set-point lowering after intraventricular administration of tetrodotoxin is provided by persistence of the ability to regulate against both heat and cold stresses during hypothermia. The possibility that the decrease in set-point could be due to the well known action of tetrodotoxin to block transient increases in membrane sodium ion conductance is discussed in terms of a recent hypothesis regarding ionic control of the thermoregulatory set-point.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196699"} {"pmid": "4196700", "title": "Scanning electron microscopy of the normal and BCG-stimulated primate respiratory tract.", "content": "Scanning electron microscopy of the normal and BCG-stimulated primate respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196700"} {"pmid": "4196698", "title": "Differential release of acetylcholine from the hypothalamus and mesencephalon of the monkey during regulation.", "content": "Differential release of acetylcholine from the hypothalamus and mesencephalon of the monkey during regulation. 1. In unanaesthetized monkeys acclimated to primate chairs, 101 isolated sites in the hypothalamus and mesencephalon were perfused at a rate of 30-50 mul./min by means of push-pull cannulae. The perfusate, which contained an anticholinesterase, was assayed for acetylcholine (ACh) activity on the guinea-pig ileum in the presence of neostigmine.2. The body temperature of each animal was monitored continuously during an experiment by colonic and brain thermistors. To alter the ambient temperature by 15-20 degrees C, either a stream of warm air was passed over the monkey's trunk or containers of ice were placed in its chair chamber to cool the same region.3. Assays of the effluent revealed that the release of ACh varied according to the ambient temperature as follows: elevated only during cooling; elevated only during warming; elevated by both thermal stimuli; suppressed only by cooling; suppressed only by warming; suppressed by both thermal stimuli; elevated during cooling but suppressed by warming; and elevated by warming and suppressed by cooling.4. A composite anatomical ;mapping' of all perfusion sites revealed that in response to either peripheral cooling or warming, the output of ACh varied at only 36% of all sites anterior to the mid-hypothalamic plane, but at 65% of those loci caudal to this coronal plane.5. In the anterior, preoptic area, cooling enhanced the output of ACh at 88% of the active releasing sites, whereas warming reduced the release of ACh at 80% of these perfusion loci. Posterior to this region, ACh release was elevated by cooling at about half of the active releasing sites, but lowered by warming at nearly every active perfusion locus. Within the mesencephalon, the ratio of the temperature-induced change in ACh release was similar but in an opposite direction, since the level of ACh in the effluent collected from two out of three sites was augmented by cooling, but diminished by warming.6. These results provide additional evidence for the neurochemical model of Myers & Yaksh (1969), which suggests that a cholinergic pathway originating in the anterior, preoptic region transmits efferent signals for heat production. Further, within the posterior hypothalamic area as well as in the mesencephalon of the monkey, the characteristics of the ACh releasing sites reflect a function delegated primarily to heat gain, although evidence of a cholinergic pathway for the heat loss system is also presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196698"} {"pmid": "4196701", "title": "Immunoglobulins as aspecific opsonins. 3. The opsonizing power of fragments of polyclonal and monoclonal immunoglobulin G.", "content": "Immunoglobulins as aspecific opsonins. 3. The opsonizing power of fragments of polyclonal and monoclonal immunoglobulin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196701"} {"pmid": "4196702", "title": "The effect of lymphocyte supernatant fluids on the intracellular growth of virulent tubercle bacilli.", "content": "The effect of lymphocyte supernatant fluids on the intracellular growth of virulent tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196702"} {"pmid": "4196693", "title": "Lactase and other enzymes bound to a phenol-formaldehyde resin with glutaraldehyde.", "content": "Lactase and other enzymes bound to a phenol-formaldehyde resin with glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196693"} {"pmid": "4196704", "title": "An intravenous fat emulsion as a nitrogen sparer: comparison with lucose.", "content": "An intravenous fat emulsion as a nitrogen sparer: comparison with lucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196704"} {"pmid": "4196703", "title": "The induction by Listeria monocytogenes and plant mitogens of lymphocyte supernatant fluids which inhibit the growth of Mycobacterium tuberculosis within macrophages in vitro.", "content": "The induction by Listeria monocytogenes and plant mitogens of lymphocyte supernatant fluids which inhibit the growth of Mycobacterium tuberculosis within macrophages in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196703"} {"pmid": "4196705", "title": "Technique of injection into the spinal cord of monkeys.", "content": "Technique of injection into the spinal cord of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196705"} {"pmid": "4196697", "title": "High voltage electron microscopy of the central nervous system in Golgi preparations.", "content": "High voltage electron microscopy of the central nervous system in Golgi preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196697"} {"pmid": "4196707", "title": "Inhibition of collagen synthesis by the proline analogue cis-4-hydroxyproline.", "content": "Inhibition of collagen synthesis by the proline analogue cis-4-hydroxyproline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196707"} {"pmid": "4196706", "title": "The pathophysiology of irreversible hemorrhagic shock in monkeys.", "content": "The pathophysiology of irreversible hemorrhagic shock in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196706"} {"pmid": "4196710", "title": "The use of 7-chlorolincomycin in the treatment of childhood respiratory disease.", "content": "The use of 7-chlorolincomycin in the treatment of childhood respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196710"} {"pmid": "4196711", "title": "Aflatoxin B 1 producing potential of isolates of Aspergillus flavus Link ex Fries from cotton, maize and wheat.", "content": "Aflatoxin B 1 producing potential of isolates of Aspergillus flavus Link ex Fries from cotton, maize and wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196711"} {"pmid": "4196712", "title": "Clinical and manometric effects of nitroglycerin in diffuse esophageal spasm.", "content": "Clinical and manometric effects of nitroglycerin in diffuse esophageal spasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196712"} {"pmid": "4196713", "title": "Replacement therapy for inherited enzyme deficiency. Use of purified ceramidetrihexosidase in Fabry's disease.", "content": "Replacement therapy for inherited enzyme deficiency. Use of purified ceramidetrihexosidase in Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196713"} {"pmid": "4196714", "title": "The environmental causes of aggression.", "content": "The environmental causes of aggression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196714"} {"pmid": "4196717", "title": "Tuberculosis drug therapy. A review.", "content": "Tuberculosis drug therapy. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196717"} {"pmid": "4196718", "title": "The time course of preparatory processes in split-brain monkeys performing a variable foreperiod reaction time task.", "content": "The time course of preparatory processes in split-brain monkeys performing a variable foreperiod reaction time task.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196718"} {"pmid": "4196719", "title": "Modifications in cortically-induced peripheral motor nerve activity induced by the center median in the cat and the squirrel monkey.", "content": "Modifications in cortically-induced peripheral motor nerve activity induced by the center median in the cat and the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196719"} {"pmid": "4196720", "title": "Urinary epinephrine and norepinephrine responses to chair restraint in the monkey.", "content": "Urinary epinephrine and norepinephrine responses to chair restraint in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196720"} {"pmid": "4196721", "title": "The enhanced efficacy of disodium cromoglycate (DSCG) in DSCG predosed rats.", "content": "The enhanced efficacy of disodium cromoglycate (DSCG) in DSCG predosed rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196721"} {"pmid": "4196722", "title": "Serological responses of patas monkeys (Erythrocebus patas) to vaccination against cholera and yellow fever.", "content": "Serological responses of patas monkeys (Erythrocebus patas) to vaccination against cholera and yellow fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196722"} {"pmid": "4196723", "title": "Vacuole formation in human erythrocyte ghosts.", "content": "Vacuole formation in human erythrocyte ghosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196723"} {"pmid": "4196724", "title": "The role of renal arteriography in pediatric hypertension.", "content": "The role of renal arteriography in pediatric hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196724"} {"pmid": "4196725", "title": "Symposium on the role of heavy particle radiation in the treatment of cancer. Introduction.", "content": "Symposium on the role of heavy particle radiation in the treatment of cancer. Introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196725"} {"pmid": "4196726", "title": "Radiobiology of heavy particle radiation therapy: cellular studies.", "content": "Radiobiology of heavy particle radiation therapy: cellular studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196726"} {"pmid": "4196727", "title": "High-LET radiation: clinical facilities available with neutron beams.", "content": "High-LET radiation: clinical facilities available with neutron beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196727"} {"pmid": "4196728", "title": "Pretherapeutic investigations with accelerated heavy ions.", "content": "Pretherapeutic investigations with accelerated heavy ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196728"} {"pmid": "4196729", "title": "A hospital-based superconducting accelerator facility for negative pi-meson beam radiotherapy.", "content": "A hospital-based superconducting accelerator facility for negative pi-meson beam radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196729"} {"pmid": "4196730", "title": "Clinical dosimetry for negative pi mesons.", "content": "Clinical dosimetry for negative pi mesons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196730"} {"pmid": "4196731", "title": "Preparation, physiology, and dosimetry of 111 In-labeled radiopharmaceuticals for cisternography.", "content": "Preparation, physiology, and dosimetry of 111 In-labeled radiopharmaceuticals for cisternography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196731"} {"pmid": "4196737", "title": "Salivary IgA in periodontal disease.", "content": "Salivary IgA in periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196737"} {"pmid": "4196738", "title": "A rapid mycobacterial drug susceptibility test.", "content": "A rapid mycobacterial drug susceptibility test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196738"} {"pmid": "4196739", "title": "Laboratory suggestions: a method for teaching the technic of electroimmunodiffusion for detection of the australia antigen and other proteins.", "content": "Laboratory suggestions: a method for teaching the technic of electroimmunodiffusion for detection of the australia antigen and other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196739"} {"pmid": "4196740", "title": "Letters to the editor: quantitation of cerebrospinal fluid proteins.", "content": "Letters to the editor: quantitation of cerebrospinal fluid proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196740"} {"pmid": "4196741", "title": "Tobramycin: bacteriological evaluation.", "content": "Tobramycin: bacteriological evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196741"} {"pmid": "4196742", "title": "The effect of Pa CO2 on the metabolism of ischemic brain in squirrel monkeys.", "content": "The effect of Pa CO2 on the metabolism of ischemic brain in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196742"} {"pmid": "4196743", "title": "Fat metabolism in higher plants. LV. Acetate uptake and accumulation by class I and II chloroplasts from Spinacia oleracea.", "content": "Fat metabolism in higher plants. LV. Acetate uptake and accumulation by class I and II chloroplasts from Spinacia oleracea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196743"} {"pmid": "4196744", "title": "Choline sulfatase of Pseudomonas aeruginosa.", "content": "Choline sulfatase of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196744"} {"pmid": "4196745", "title": "Long-term continuous exposure to sulfuric acid mist in cynomolgus monkeys and guinea pigs.", "content": "Long-term continuous exposure to sulfuric acid mist in cynomolgus monkeys and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196745"} {"pmid": "4196747", "title": "Fastigial nucleus connections to the septal region in monkey and cat: a demonstration with evoked potentials of a bilateral pathway.", "content": "Fastigial nucleus connections to the septal region in monkey and cat: a demonstration with evoked potentials of a bilateral pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196747"} {"pmid": "4196749", "title": "Age effects of social behavior deficits following prefrontal lesions in monkeys.", "content": "Age effects of social behavior deficits following prefrontal lesions in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196749"} {"pmid": "4196750", "title": "Multiple coding of species-specific vocalizations in the auditory cortex of squirrel monkeys.", "content": "Multiple coding of species-specific vocalizations in the auditory cortex of squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196750"} {"pmid": "4196751", "title": "An ultrastructural study of the centre median and ventrolateral thalamic nuclei of the monkey.", "content": "An ultrastructural study of the centre median and ventrolateral thalamic nuclei of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196751"} {"pmid": "4196752", "title": "An ultrastructural study of the termination of afferent fibres within the ventrolateral and centre median nuclei of the monkey thalamus.", "content": "An ultrastructural study of the termination of afferent fibres within the ventrolateral and centre median nuclei of the monkey thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196752"} {"pmid": "4196753", "title": "The effect of prenatal malnutrition on dimensions of cerebral cortex.", "content": "The effect of prenatal malnutrition on dimensions of cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196753"} {"pmid": "4196746", "title": "The in vitro incorporation of ( 3 H)thymidine into DNA and of 32 P into phospholipids and RNA in the aorta of Rhesus monkeys during early atherogenesis.", "content": "The in vitro incorporation of ( 3 H)thymidine into DNA and of 32 P into phospholipids and RNA in the aorta of Rhesus monkeys during early atherogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196746"} {"pmid": "4196781", "title": "Experimental immunization with attenuated mutants of Pseudomonas aeruginosa.", "content": "Experimental immunization with attenuated mutants of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196781"} {"pmid": "4196782", "title": "Autodegradation of RNA of bacterial ribosomes.", "content": "Autodegradation of RNA of bacterial ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196782"} {"pmid": "4196783", "title": "Corticosteroid ointments: comparison by two human bioassays.", "content": "Corticosteroid ointments: comparison by two human bioassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196783"} {"pmid": "4196784", "title": "Value of an acetaminophen-chlorzoxazone combination (parafon forte) in the treatment of acute musculoskeletal disorders.", "content": "Value of an acetaminophen-chlorzoxazone combination (parafon forte) in the treatment of acute musculoskeletal disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196784"} {"pmid": "4196785", "title": "Evaluation of a bacteriostatic soap, P-300, on skin flora of patients in protected environments.", "content": "Evaluation of a bacteriostatic soap, P-300, on skin flora of patients in protected environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196785"} {"pmid": "4196786", "title": "A double-blind comparison of thioridazine (Mellaril) versus diazepam (valium) in patients with chronic mixed anxiety and depressive symptoms.", "content": "A double-blind comparison of thioridazine (Mellaril) versus diazepam (valium) in patients with chronic mixed anxiety and depressive symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196786"} {"pmid": "4196787", "title": "On the anti-anxiety properties of a new benzodiazepine, ORF 8063.", "content": "On the anti-anxiety properties of a new benzodiazepine, ORF 8063.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196787"} {"pmid": "4196788", "title": "When to use cytotoxic drugs in rheumatoid arthritis.", "content": "When to use cytotoxic drugs in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196788"} {"pmid": "4196789", "title": "Planning a treatment program for rheumatoid arthritis.", "content": "Planning a treatment program for rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196789"} {"pmid": "4196790", "title": "A contribution to the microbiology of urethritis.", "content": "A contribution to the microbiology of urethritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196790"} {"pmid": "4196791", "title": "A comparison between the clearances of inulin, endogenous creatinine and 51 Cr-EDTA.", "content": "A comparison between the clearances of inulin, endogenous creatinine and 51 Cr-EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196791"} {"pmid": "4196792", "title": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). I. The locus caeruleus.", "content": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). I. The locus caeruleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196792"} {"pmid": "4196794", "title": "Increased virulence of the E vaccine strain of Rickettsia prowazeki passaged in the lungs of white mice and guinea pigs.", "content": "Increased virulence of the E vaccine strain of Rickettsia prowazeki passaged in the lungs of white mice and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196794"} {"pmid": "4196793", "title": "Mechanisms in the suppression of delayed hypersensitivity in the guinea pig by 6-mercaptopurine.", "content": "Mechanisms in the suppression of delayed hypersensitivity in the guinea pig by 6-mercaptopurine. The mechanism of suppression, of delayed hypersensitivity to tuberculoprotein by 6-mercaptopurine (6-MP) was studied in guinea pigs. Under the conditions of the protocol, suppression of tuberculin delayed skin test reactivity was not associated with a significantly altered end-organ response to mediators of permeability. No significant alteration of in vivo lymphoid activity, as measured by reconstitution studies, was found. In addition, lymphoid cells from 6-MP-treated animals reacted in a fashion similar to those of placebo-treated animals with respect to (a) antigen-induced lymphocyte proliferation, (b) antigen-induced liberation of macrophage inhibitory factor activity, (c) direct inhibition by antigen of peritoneal exudate cell migration. Conversely, suppression was seen in levels of blood monocytes and in vitro function of macrophages from 6-MP-treated animals in several respects: (a) adherence to glass, (b) migratory rate, (c) phagocytic capacity. Therefore, it would appear that a ma]or mechanism of 6-MP-induced suppression of delayed hypersensitivity is through its action on effector cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196793"} {"pmid": "4196795", "title": "Use of the microprecipitation method in agar gel (MPA) in the diagnostics of toxoplasmosis. 3. Correlation of MPA, complement-fixation reaction (CFT) and Sabin-Feldman's dye test (SFT) in serodiagnosis of human toxoplasmosis.", "content": "Use of the microprecipitation method in agar gel (MPA) in the diagnostics of toxoplasmosis. 3. Correlation of MPA, complement-fixation reaction (CFT) and Sabin-Feldman's dye test (SFT) in serodiagnosis of human toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196795"} {"pmid": "4196797", "title": "Hyaluronidase applied to the gingiva of rhesus monkeys.", "content": "Hyaluronidase applied to the gingiva of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196797"} {"pmid": "4196796", "title": "Prevention of development of carriers in typhoid and paratyphoid fever.", "content": "Prevention of development of carriers in typhoid and paratyphoid fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196796"} {"pmid": "4196798", "title": "International trends toward humanization of health services.", "content": "International trends toward humanization of health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196798"} {"pmid": "4196802", "title": "All volunteer: military medicine tomorrow.", "content": "All volunteer: military medicine tomorrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196802"} {"pmid": "4196801", "title": "Contraceptive steroids: modifications of carbohydrate and lipid metabolism.", "content": "Contraceptive steroids: modifications of carbohydrate and lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196801"} {"pmid": "4196803", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196803"} {"pmid": "4196804", "title": "PABA. A more effective sunscreen.", "content": "PABA. A more effective sunscreen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196804"} {"pmid": "4196805", "title": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. 3. Survey methods.", "content": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. 3. Survey methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196805"} {"pmid": "4196806", "title": "Patterns of illicit drug use in viral hepatitis patients.", "content": "Patterns of illicit drug use in viral hepatitis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196806"} {"pmid": "4196807", "title": "Prognostic scales for personality disorders in the Naval Service.", "content": "Prognostic scales for personality disorders in the Naval Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196807"} {"pmid": "4196808", "title": "Characteristics of naval recruits with histories of drug abuse.", "content": "Characteristics of naval recruits with histories of drug abuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196808"} {"pmid": "4196809", "title": "The evolution of the support of medical research in the Veterans Administration.", "content": "The evolution of the support of medical research in the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196809"} {"pmid": "4196812", "title": "Aflatoxicosis in the laying Japanese quail (Coturnix coturnix japonica).", "content": "Aflatoxicosis in the laying Japanese quail (Coturnix coturnix japonica).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196812"} {"pmid": "4196814", "title": "Avian riboflavinuria. 8. The fate of the riboflavin-binding protein-riboflavin complex during incubation of hen's eggs.", "content": "Avian riboflavinuria. 8. The fate of the riboflavin-binding protein-riboflavin complex during incubation of hen's eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196814"} {"pmid": "4196813", "title": "Nonsusceptibility of some avian species to turkey leucocytozoon infection.", "content": "Nonsusceptibility of some avian species to turkey leucocytozoon infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196813"} {"pmid": "4196815", "title": "Extraction of calcium from blood fibrin with a solution of tetrasodium-ethylenediaminetetraacetate (Na4EDTA).", "content": "Extraction of calcium from blood fibrin with a solution of tetrasodium-ethylenediaminetetraacetate (Na4EDTA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196815"} {"pmid": "4196816", "title": "Thyroid metabolism of chickens. 1. Estimation of hormone concentration by the thyroxine binding globulin technique.", "content": "Thyroid metabolism of chickens. 1. Estimation of hormone concentration by the thyroxine binding globulin technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196816"} {"pmid": "4196819", "title": "The nurse's role in parenteral hyperalimentation.", "content": "The nurse's role in parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196819"} {"pmid": "4196820", "title": "104 days with Rodney K.", "content": "104 days with Rodney K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196820"} {"pmid": "4196821", "title": "Dodecyldiaminoethyl glycine as an inhibitor of bacteria, fungi and dental plauqes.", "content": "Dodecyldiaminoethyl glycine as an inhibitor of bacteria, fungi and dental plauqes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196821"} {"pmid": "4196830", "title": "Basic thalamic structure and function. Introductory remarks.", "content": "Basic thalamic structure and function. Introductory remarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196830"} {"pmid": "4196831", "title": "Some principles of organization in the dorsal lateral geniculate nucleus.", "content": "Some principles of organization in the dorsal lateral geniculate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196831"} {"pmid": "4196832", "title": "The medial geniculate body and associated thalamic cell groups: behavioral studies.", "content": "The medial geniculate body and associated thalamic cell groups: behavioral studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196832"} {"pmid": "4196833", "title": "On the organisation of the visual cortical projection to the pulvinar in Macaca mulatta.", "content": "On the organisation of the visual cortical projection to the pulvinar in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196833"} {"pmid": "4196834", "title": "The connections of the dorsomedial nuclei.", "content": "The connections of the dorsomedial nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196834"} {"pmid": "4196835", "title": "Chemosterilization of the tropical house mosquito Culex pipiens fatigans Wied.: laboratory and field cage studies.", "content": "Chemosterilization of the tropical house mosquito Culex pipiens fatigans Wied.: laboratory and field cage studies. Tris(1-aziridinyl)phosphine sulfide was found to be an excellent sterilant for male Culex pipiens fatigans. When male pupae were exposed to a 0.6% solution for 3 hours, the ensuing adults were rendered permanently sterile with no apparent reduction in their vigour or longevity based on laboratory and field cage studies. Females, however, exposed to the same dosage for the same length of time were partially fertile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196835"} {"pmid": "4196836", "title": "WHO cooperative studies on the phage-typing of mycobacteria. 1. Phage lysis of Czechoslovak and Italian strains of Mycobacterium tuberculosis.", "content": "WHO cooperative studies on the phage-typing of mycobacteria. 1. Phage lysis of Czechoslovak and Italian strains of Mycobacterium tuberculosis. Although phage-typing of some pathogenic microbes-e.g., Escherichia coli and the genera Salmonella, Staphylococcus, and Streptomyces-is in routine use, little progress has yet been made in the phage-typing of mycobacteria, chiefly because mycobacteriophages possess a polyvalence that prevents the reliable identification of individual species of mycobacterium. Furthermore, laboratories cannot compare their results because they employ different methods and culture media and also because the phages used cannot be accurately identified. It has been shown that internationally reproducible results can be obtained for M. tuberculosis by selecting suitable mycobacteriophages and sensitive culture media, and by using a standardized technique of phage-typing. Under these conditions, phage lysis may be utilized to classify strains of M. tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196836"} {"pmid": "4196837", "title": "Management and marketing in health care. Some lessons for the United States from the British system.", "content": "Management and marketing in health care. Some lessons for the United States from the British system. The British health care system has been examined by sociologists, political scientists, and medical care specialists before, but in this presentation a section of the British health care system is viewed through the eyes of modern business management, particularly as to cost and consumer effectiveness. Examination of positive features as well as problems may be helpful in relation to some future health care delivery system in the United States. Cross fertilization between the disciplines of management and medicine has much to offer to the rapidly changing delivery of health care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196837"} {"pmid": "4196839", "title": "Human placental lactogen in high-risk pregnancy.", "content": "Human placental lactogen in high-risk pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196839"} {"pmid": "4196838", "title": "Effects of prenatal nutrition upon pregnancy risk.", "content": "Effects of prenatal nutrition upon pregnancy risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196838"} {"pmid": "4196840", "title": "Hemolytic disease.", "content": "Hemolytic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196840"} {"pmid": "4196841", "title": "Calories versus protein in children's nutrition.", "content": "Calories versus protein in children's nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196841"} {"pmid": "4196842", "title": "Hemorrhagic disease due to vitamin K deficiency in a premature infant: a syndrome which may resemble disseminated intravascular coagulation (DIC).", "content": "Hemorrhagic disease due to vitamin K deficiency in a premature infant: a syndrome which may resemble disseminated intravascular coagulation (DIC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196842"} {"pmid": "4196843", "title": "Plumbism at the Green Parrot Goat Farm.", "content": "Plumbism at the Green Parrot Goat Farm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196843"} {"pmid": "4196844", "title": "Decreased performance behavior with carbaryl--an indication of clinical toxicity.", "content": "Decreased performance behavior with carbaryl--an indication of clinical toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196844"} {"pmid": "4196845", "title": "Comparative study of peroxidases from the thyroid and the submaxillary gland of goat (Ca pra hiscus).", "content": "Comparative study of peroxidases from the thyroid and the submaxillary gland of goat (Ca pra hiscus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196845"} {"pmid": "4196847", "title": "Cell density as a selective parameter in Tetrahymena.", "content": "Cell density as a selective parameter in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196847"} {"pmid": "4196846", "title": "Comparative studies of anti-A agglutinins from various snails of the genus Helix (Helix pomatia and Helix aspersa).", "content": "Comparative studies of anti-A agglutinins from various snails of the genus Helix (Helix pomatia and Helix aspersa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196846"} {"pmid": "4196848", "title": "Changes caused by air-drying and alcohol dehydration of spread insect sperm and fungal spore chromosome fibres.", "content": "Changes caused by air-drying and alcohol dehydration of spread insect sperm and fungal spore chromosome fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196848"} {"pmid": "4196849", "title": "Histochemical and biochemical studies on the localization and activity of lysosomal enzymes in fracture callus.", "content": "Histochemical and biochemical studies on the localization and activity of lysosomal enzymes in fracture callus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196849"} {"pmid": "4196850", "title": "Occurrence of the genotype Cde-Cde in Papua New Guinea.", "content": "Occurrence of the genotype Cde-Cde in Papua New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196850"} {"pmid": "4196851", "title": "Present status and future problems of medical care in Japan.", "content": "Present status and future problems of medical care in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196851"} {"pmid": "4196852", "title": "Blood group genetic patterns and heterogeneity in New Guinea.", "content": "Blood group genetic patterns and heterogeneity in New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196852"} {"pmid": "4196854", "title": "Purification and properties of pyocin S2.", "content": "Purification and properties of pyocin S2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196854"} {"pmid": "4196853", "title": "Degenerative myelopathy in the aging German Shepherd dog: clinical and pathologic findings.", "content": "Degenerative myelopathy in the aging German Shepherd dog: clinical and pathologic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196853"} {"pmid": "4196855", "title": "Immunological cross-reaction between thiol proteases of plant origin: stem and fruit bromelains.", "content": "Immunological cross-reaction between thiol proteases of plant origin: stem and fruit bromelains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196855"} {"pmid": "4196856", "title": "Bioautography in paper and thin-layer chromatography and its scope in the antibiotic field.", "content": "Bioautography in paper and thin-layer chromatography and its scope in the antibiotic field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196856"} {"pmid": "4196857", "title": "Gonococcal septicemia.", "content": "Gonococcal septicemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196857"} {"pmid": "4196858", "title": "A check-list of the species of the genus Leucocytozoon (Apicomplexa, Plasmodiidae).", "content": "A check-list of the species of the genus Leucocytozoon (Apicomplexa, Plasmodiidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196858"} {"pmid": "4196859", "title": "The resorption of cilia in Cyathodinium piriforme.", "content": "The resorption of cilia in Cyathodinium piriforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196859"} {"pmid": "4196860", "title": "East Coast fever of cattle: 60 Co irradiation of infective particles of Theileria parva.", "content": "East Coast fever of cattle: 60 Co irradiation of infective particles of Theileria parva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196860"} {"pmid": "4196861", "title": "Sublethal cytotoxic effects of mercuric chloride on the ciliate Tetrahymena pyriformis.", "content": "Sublethal cytotoxic effects of mercuric chloride on the ciliate Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196861"} {"pmid": "4196862", "title": "The conversion of phenylalanine to tyrosine in Tetrahymena pyriformis.", "content": "The conversion of phenylalanine to tyrosine in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196862"} {"pmid": "4196866", "title": "Changes in relative frequencies of behaviors in pigtail monkeys (Macaca nemistrina) following dorsolateral frontal ablations.", "content": "Changes in relative frequencies of behaviors in pigtail monkeys (Macaca nemistrina) following dorsolateral frontal ablations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196866"} {"pmid": "4196865", "title": "Influence of the implantation of Lactobacillus acidophilus in chicks on the growth, feed conversion, malabsorption of fats syndrome and intestinal flora.", "content": "Influence of the implantation of Lactobacillus acidophilus in chicks on the growth, feed conversion, malabsorption of fats syndrome and intestinal flora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196865"} {"pmid": "4196867", "title": "The effects of N,N-dimethyltryptamine on operant behavior in squirrel monkeys.", "content": "The effects of N,N-dimethyltryptamine on operant behavior in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196867"} {"pmid": "4196869", "title": "Electron optical investigations on the morphological alterations produced by subacute sclerosing panencephalitis (SSPE) virus in Cercopithecus aethiops (R 6 CA) kidney cells.", "content": "Electron optical investigations on the morphological alterations produced by subacute sclerosing panencephalitis (SSPE) virus in Cercopithecus aethiops (R 6 CA) kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196869"} {"pmid": "4196870", "title": "Comparative investigations on immunodiffusion methods for detecting Australia antigen.", "content": "Comparative investigations on immunodiffusion methods for detecting Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196870"} {"pmid": "4196871", "title": "Technique for making evident the precipitation bands obtained in immunodiffusion reactions gel.", "content": "Technique for making evident the precipitation bands obtained in immunodiffusion reactions gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196871"} {"pmid": "4196874", "title": "Sarcocystis in mice inoculated with toxoplasma-like oocysts from cat feces.", "content": "Sarcocystis in mice inoculated with toxoplasma-like oocysts from cat feces. Sarcocysts morphologically similar to Sarcocystis muris were observed in mice after inoculation with Toxoplasma-like oocysts found in feces of a stray cat. Cats that were fed mice infected with the oocysts shed similar oocysts in their feces. Sarcocysts were found histologically in about 50 percent of mice inoculated with 40,000 or more oocysts and examined 42 days or longer after exposure. Most inoculated mice developed low Toxoplasma dye-test antibody titers 3 to 4 weeks after exposure, but Toxoplasma antibody was usually not detectable in infected cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196874"} {"pmid": "4196884", "title": "Hypothalamo-pituitary interrelationships in thyroid pathology, with special reference to cretinism.", "content": "Hypothalamo-pituitary interrelationships in thyroid pathology, with special reference to cretinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196884"} {"pmid": "4196886", "title": "Role of the placenta and of plasma hormone binding in the pathogenesis of cretinism.", "content": "Role of the placenta and of plasma hormone binding in the pathogenesis of cretinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196886"} {"pmid": "4196885", "title": "Hypothalamic hypothyroidism: its possible relationshp to endemic goiter.", "content": "Hypothalamic hypothyroidism: its possible relationshp to endemic goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196885"} {"pmid": "4196887", "title": "Alcohol preference.", "content": "Alcohol preference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196887"} {"pmid": "4196888", "title": "Studies of the development of alcohol addiction in infant monkeys.", "content": "Studies of the development of alcohol addiction in infant monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196888"} {"pmid": "4196890", "title": "Animal models of ethanol dependency.", "content": "Animal models of ethanol dependency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196890"} {"pmid": "4196889", "title": "The reinforcing property of ethanol in the rhesus monkey. I. Initiation, maintenance and termination of intravenous ethanol-reinforced responding.", "content": "The reinforcing property of ethanol in the rhesus monkey. I. Initiation, maintenance and termination of intravenous ethanol-reinforced responding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196889"} {"pmid": "4196891", "title": "Biochemical and metabolic aspects of alcoholism.", "content": "Biochemical and metabolic aspects of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196891"} {"pmid": "4196894", "title": "The affinity and temporal variation of isoelectric fractions of rabbit anti-lactose antibody.", "content": "The affinity and temporal variation of isoelectric fractions of rabbit anti-lactose antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196894"} {"pmid": "4196895", "title": "Fatty acid synthetase activity in Euglena gracilis variety bacillarius. Characterization of an acyl carrier protein dependent system.", "content": "Fatty acid synthetase activity in Euglena gracilis variety bacillarius. Characterization of an acyl carrier protein dependent system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196895"} {"pmid": "4196896", "title": "Stopped-flow studies of high pH activity and acetazolamide inhibition of bovine carbonic anhydrase. Enzyme-catalyzed hydrolyses of 3-pyridyl and nitro-3-pyridyl acetates.", "content": "Stopped-flow studies of high pH activity and acetazolamide inhibition of bovine carbonic anhydrase. Enzyme-catalyzed hydrolyses of 3-pyridyl and nitro-3-pyridyl acetates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196896"} {"pmid": "4196898", "title": "Preoperative irradiation for osteogenic sarcoma.", "content": "Preoperative irradiation for osteogenic sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196898"} {"pmid": "4196897", "title": "The reaction of phenyl N-methylacetimidate with bovine serum albumin and bovine carbonic anhydrase.", "content": "The reaction of phenyl N-methylacetimidate with bovine serum albumin and bovine carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196897"} {"pmid": "4196899", "title": "Increased alkaline phosphatase in the tissues and hemolymph of the snail Biomphalaria glabrata infected with Schistosoma mansoni.", "content": "Increased alkaline phosphatase in the tissues and hemolymph of the snail Biomphalaria glabrata infected with Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196899"} {"pmid": "4196900", "title": "The complex of ATP-dependent deoxyribonuclease from Bacillus subtilis with DNA and its thermostability.", "content": "The complex of ATP-dependent deoxyribonuclease from Bacillus subtilis with DNA and its thermostability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196900"} {"pmid": "4196902", "title": "Preparation of mammalian gametes and reproductive tract tissues for scanning electron microscopy.", "content": "Preparation of mammalian gametes and reproductive tract tissues for scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196902"} {"pmid": "4196901", "title": "Carbon-13 nuclear magnetic resonance studies on thyrotropin-releasing factor and related peptides.", "content": "Carbon-13 nuclear magnetic resonance studies on thyrotropin-releasing factor and related peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196901"} {"pmid": "4196903", "title": "Lysis of lyophilized escherichia coli cells with egg-white lysozyme without ethylenediaminetetraacetic acid.", "content": "Lysis of lyophilized escherichia coli cells with egg-white lysozyme without ethylenediaminetetraacetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196903"} {"pmid": "4196905", "title": "Triple massive-dose drug therapy in combined treatment of advanced ovarian carcinoma.", "content": "Triple massive-dose drug therapy in combined treatment of advanced ovarian carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196905"} {"pmid": "4196907", "title": "Development of a single, simple in vitro thyroid function test.", "content": "Development of a single, simple in vitro thyroid function test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196907"} {"pmid": "4196906", "title": "A method of correcting for collimator penetration by high energy gamma rays.", "content": "A method of correcting for collimator penetration by high energy gamma rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196906"} {"pmid": "4196959", "title": "The distribution of l-thyroxine labeled with radioactive iodine-125 in the ears of squirrel monkeys.", "content": "The distribution of l-thyroxine labeled with radioactive iodine-125 in the ears of squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196959"} {"pmid": "4196958", "title": "The effects of antimalarial drugs on nucleic acid synthesis in vitro in Tetrahymena pyriformis.", "content": "The effects of antimalarial drugs on nucleic acid synthesis in vitro in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196958"} {"pmid": "4196960", "title": "Study of efficiency of some modifications of medium B-2 for the primary cultivation of tubercle bacteria.", "content": "Study of efficiency of some modifications of medium B-2 for the primary cultivation of tubercle bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196960"} {"pmid": "4196961", "title": "Detection of vaccinia antigen and antibody by counterelectrophoresis.", "content": "Detection of vaccinia antigen and antibody by counterelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196961"} {"pmid": "4196962", "title": "[Diagnosis and therapy of pyelonephritis in various age groups].", "content": "[Diagnosis and therapy of pyelonephritis in various age groups].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196962"} {"pmid": "4196968", "title": "Mitotic activity of peritoneum in contact with a regenerating area of peritoneum.", "content": "Mitotic activity of peritoneum in contact with a regenerating area of peritoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196968"} {"pmid": "4196969", "title": "Variations in crypt cell cycle time and mitotic time in the small intestine of the rat.", "content": "Variations in crypt cell cycle time and mitotic time in the small intestine of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196969"} {"pmid": "4196970", "title": "The pars distalis of the pituitary as a source of liver growth stimulating factors during liver regeneration.", "content": "The pars distalis of the pituitary as a source of liver growth stimulating factors during liver regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196970"} {"pmid": "4196974", "title": "The influence of temperate bacteriophage phi105 on transformation and transfection in Bacillus subtilis.", "content": "The influence of temperate bacteriophage phi105 on transformation and transfection in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196974"} {"pmid": "4196975", "title": "Lactose synthetase in mammary gland of the California sea lion.", "content": "Lactose synthetase in mammary gland of the California sea lion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196975"} {"pmid": "4196977", "title": "The optical rotatory properties of poly- -D-glutamic acid.", "content": "The optical rotatory properties of poly- -D-glutamic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196977"} {"pmid": "4196976", "title": "The effect of 2-mercaptoethanol (ME) and EDTA on the sub-species structure of horse liver alcohol dehydrogenase (LADH) in 8 M urea.", "content": "The effect of 2-mercaptoethanol (ME) and EDTA on the sub-species structure of horse liver alcohol dehydrogenase (LADH) in 8 M urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196976"} {"pmid": "4196980", "title": "The psychiatric nonhospital: a model for change.", "content": "The psychiatric nonhospital: a model for change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196980"} {"pmid": "4196978", "title": "Conformational studies of anthrax polypeptide, subtilis polypeptide, and synthetic poly- -L-glutamic acid.", "content": "Conformational studies of anthrax polypeptide, subtilis polypeptide, and synthetic poly- -L-glutamic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196978"} {"pmid": "4196981", "title": "Control of pain and infection.", "content": "Control of pain and infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196981"} {"pmid": "4196982", "title": "Storage iron kinetics. 3. Study of desferrioxamine action by selective radioiron labels of RE and parenchymal cells.", "content": "Storage iron kinetics. 3. Study of desferrioxamine action by selective radioiron labels of RE and parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196982"} {"pmid": "4196983", "title": "Brain cholesterol. XVI. Incorporation of different precursors into baboon tissue sterol.", "content": "Brain cholesterol. XVI. Incorporation of different precursors into baboon tissue sterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196983"} {"pmid": "4196984", "title": "Insulin response to intravenous alimentation.", "content": "Insulin response to intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196984"} {"pmid": "4196973", "title": "Myocardial steal produced by coronary vasocilation in chronic coronary artery occlusion.", "content": "Myocardial steal produced by coronary vasocilation in chronic coronary artery occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196973"} {"pmid": "4196985", "title": "Hypothalamic hypopituitarism. A case of panhypopituitarism with TSH and LH deficiency of hypothalamic origin.", "content": "Hypothalamic hypopituitarism. A case of panhypopituitarism with TSH and LH deficiency of hypothalamic origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196985"} {"pmid": "4196986", "title": "Cerebrospinal fluid transferrin II studies in ischemic disorders of the central nervous system.", "content": "Cerebrospinal fluid transferrin II studies in ischemic disorders of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196986"} {"pmid": "4196987", "title": "Antibiotic stability in solutions used for intravenous nutrition and fluid therapy.", "content": "Antibiotic stability in solutions used for intravenous nutrition and fluid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196987"} {"pmid": "4196988", "title": "Successfully treated candida endophthalmitis in a child.", "content": "Successfully treated candida endophthalmitis in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196988"} {"pmid": "4196992", "title": "Mixed lymphocyte reactivity in rhesus sibships.", "content": "Mixed lymphocyte reactivity in rhesus sibships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196992"} {"pmid": "4196997", "title": "The efferent neural supply to the vertebrate ear.", "content": "The efferent neural supply to the vertebrate ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196997"} {"pmid": "4196998", "title": "Electrical activity of single auditory nerve fibers.", "content": "Electrical activity of single auditory nerve fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196998"} {"pmid": "4196999", "title": "Noise-and drug-induced hearing loss in monkeys.", "content": "Noise-and drug-induced hearing loss in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4196999"} {"pmid": "4197001", "title": "HOE 296, a new antimycotic compound with a broad antimicrobial spectrum. Laboratory results.", "content": "HOE 296, a new antimycotic compound with a broad antimicrobial spectrum. Laboratory results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197001"} {"pmid": "4197003", "title": "The synthesis and metabolic fate of 14 C-viminol, a new analgesic, in the rat and the dog.", "content": "The synthesis and metabolic fate of 14 C-viminol, a new analgesic, in the rat and the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197003"} {"pmid": "4197004", "title": "Immobilized enzymes: the catalytic properties of lactate dehydrogenase convalently attached to glass beads.", "content": "Immobilized enzymes: the catalytic properties of lactate dehydrogenase convalently attached to glass beads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197004"} {"pmid": "4197005", "title": "Specific binding of ribonucleic acid by antiadenosine antibodies.", "content": "Specific binding of ribonucleic acid by antiadenosine antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197005"} {"pmid": "4197006", "title": "Plasmic degradation of human fibrinogen. II. Further characterization of fragment D.", "content": "Plasmic degradation of human fibrinogen. II. Further characterization of fragment D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197006"} {"pmid": "4197007", "title": "Immunochemical studies on lactate dehydrogenase.", "content": "Immunochemical studies on lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197007"} {"pmid": "4197008", "title": "Stabilization of Bacillus subtilis -amylase by amino group acylation.", "content": "Stabilization of Bacillus subtilis -amylase by amino group acylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197008"} {"pmid": "4197011", "title": "\"Photo-onycholysis\" due to tetracycline.", "content": "\"Photo-onycholysis\" due to tetracycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197011"} {"pmid": "4197012", "title": "GENERAL ASPECTS OF INFECTION CONTROL IN THE OPERATING ROOM AND INTENSIVE CARE UNIT.", "content": "GENERAL ASPECTS OF INFECTION CONTROL IN THE OPERATING ROOM AND INTENSIVE CARE UNIT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197012"} {"pmid": "4197013", "title": "New models in geriatrics and long-term care.", "content": "New models in geriatrics and long-term care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197013"} {"pmid": "4197014", "title": "Federal government involvement in training medical directors of long-term care facilities.", "content": "Federal government involvement in training medical directors of long-term care facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197014"} {"pmid": "4197015", "title": "Edema of the spinal cord following experimental impact trauma.", "content": "Edema of the spinal cord following experimental impact trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197015"} {"pmid": "4197016", "title": "Experimental local thalamic application of xylocaine through silicone rubber chemode.", "content": "Experimental local thalamic application of xylocaine through silicone rubber chemode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197016"} {"pmid": "4197017", "title": "Localized renal parenchymal infections in children.", "content": "Localized renal parenchymal infections in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197017"} {"pmid": "4197018", "title": "Milk-of-calcium in caliceal diverticulum.", "content": "Milk-of-calcium in caliceal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197018"} {"pmid": "4197019", "title": "A study on proteolytic oral microorganisms.", "content": "A study on proteolytic oral microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197019"} {"pmid": "4197021", "title": "Metabolism of the hydroxyethylrutosides. Biliary and urinary excretion of 3',4',5-(hydroxyethyl- 14 C), 7-tetra-O-( -hydroxyethyl)-rutoside in rats and monkeys after parenteral administration.", "content": "Metabolism of the hydroxyethylrutosides. Biliary and urinary excretion of 3',4',5-(hydroxyethyl- 14 C), 7-tetra-O-( -hydroxyethyl)-rutoside in rats and monkeys after parenteral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197021"} {"pmid": "4197023", "title": "Protection from exercise-induced asthma by pre-exercise cromolyn sodium and its relationship to serum IGE levels.", "content": "Protection from exercise-induced asthma by pre-exercise cromolyn sodium and its relationship to serum IGE levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197023"} {"pmid": "4197024", "title": "Thyrotropin releasing hormone: secretion and actions.", "content": "Thyrotropin releasing hormone: secretion and actions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197024"} {"pmid": "4197025", "title": "The purification and properties of an extracellular protease from Aspergillus oryzae NRRL 2160.", "content": "The purification and properties of an extracellular protease from Aspergillus oryzae NRRL 2160.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197025"} {"pmid": "4197026", "title": "Iron binding of gastric mucins.", "content": "Iron binding of gastric mucins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197026"} {"pmid": "4197028", "title": "The unstable oblique distal fibular fracture.", "content": "The unstable oblique distal fibular fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197028"} {"pmid": "4197027", "title": "Some biochemical properties of a cryomacroglobulin.", "content": "Some biochemical properties of a cryomacroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197027"} {"pmid": "4197029", "title": "Nucleotide metabolism in the whole blood of various vertebrates: enzyme levels and the use of high pressure liquid chromatography for the determination of nucleotide patterns.", "content": "Nucleotide metabolism in the whole blood of various vertebrates: enzyme levels and the use of high pressure liquid chromatography for the determination of nucleotide patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197029"} {"pmid": "4197030", "title": "Clinical implications of Medicare upon an extended-care facility population.", "content": "Clinical implications of Medicare upon an extended-care facility population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197030"} {"pmid": "4197032", "title": "Autologous tooth transplantations.", "content": "Autologous tooth transplantations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197032"} {"pmid": "4197033", "title": "Connecticut dentists' views on expanded duty dental auxiliaries--preliminary report.", "content": "Connecticut dentists' views on expanded duty dental auxiliaries--preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197033"} {"pmid": "4197034", "title": "Panoramic radiology--1973.", "content": "Panoramic radiology--1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197034"} {"pmid": "4197036", "title": "Replantation case and technic.", "content": "Replantation case and technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197036"} {"pmid": "4197035", "title": "What is our condition to be?", "content": "What is our condition to be?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197035"} {"pmid": "4197037", "title": "A surgical approach to the problem lower denture.", "content": "A surgical approach to the problem lower denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197037"} {"pmid": "4197038", "title": "Hydrotherapy in dentistry.", "content": "Hydrotherapy in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197038"} {"pmid": "4197039", "title": "Carbaryl synergism by substituted 1,3-benzodioxoles and related compounds and inhibition of mixed function oxidase.", "content": "Carbaryl synergism by substituted 1,3-benzodioxoles and related compounds and inhibition of mixed function oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197039"} {"pmid": "4197040", "title": "The marmoset periodontium in health and disease.", "content": "The marmoset periodontium in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197040"} {"pmid": "4197044", "title": "Studies of the metabolism and distribution of prothrombin in healthy men with homologous 125 I-prothrombin.", "content": "Studies of the metabolism and distribution of prothrombin in healthy men with homologous 125 I-prothrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197044"} {"pmid": "4197046", "title": "The effect of several tissue thromboplastins on the activation of the abnormal factor X (factor X Friuli).", "content": "The effect of several tissue thromboplastins on the activation of the abnormal factor X (factor X Friuli).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197046"} {"pmid": "4197047", "title": "Identification of fibrinogen derivatives in plasma samples.", "content": "Identification of fibrinogen derivatives in plasma samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197047"} {"pmid": "4197048", "title": "Measurement of fibrin proteolysis in vivo by a radioactive fibrin-millipore tube technique.", "content": "Measurement of fibrin proteolysis in vivo by a radioactive fibrin-millipore tube technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197048"} {"pmid": "4197053", "title": "Use of antibody synergism to screen human multiparous sera for lymphocytotoxins.", "content": "Use of antibody synergism to screen human multiparous sera for lymphocytotoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197053"} {"pmid": "4197054", "title": "Antisera to lysosomes. Effect on allograft rejection.", "content": "Antisera to lysosomes. Effect on allograft rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197054"} {"pmid": "4197049", "title": "The rhesus monkey as a model for evaluation of the preservation of stored whole blood.", "content": "The rhesus monkey as a model for evaluation of the preservation of stored whole blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197049"} {"pmid": "4197050", "title": "Selected types of frozen blood for patients with multiple blood group antibodies.", "content": "Selected types of frozen blood for patients with multiple blood group antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197050"} {"pmid": "4197052", "title": "Hemolytic disease of the newborn due to anti-Js a .", "content": "Hemolytic disease of the newborn due to anti-Js a .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197052"} {"pmid": "4197051", "title": "A method for preservation of papainized and Rh-sensitized red cells.", "content": "A method for preservation of papainized and Rh-sensitized red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197051"} {"pmid": "4197062", "title": "Central venous alimentation.", "content": "Central venous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197062"} {"pmid": "4197063", "title": "A specific method for the quantitative determination of -glucose-1-phosphate.", "content": "A specific method for the quantitative determination of -glucose-1-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197063"} {"pmid": "4197064", "title": "A compilation of amino acid analyses of proteins. IV. Residues per thousand residues series 1.", "content": "A compilation of amino acid analyses of proteins. IV. Residues per thousand residues series 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197064"} {"pmid": "4197065", "title": "Precipitation of RNA, DNA, and nucleoprotein particles from very dilute solutions.", "content": "Precipitation of RNA, DNA, and nucleoprotein particles from very dilute solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197065"} {"pmid": "4197066", "title": "EDTA prevents the photocatalyzed destruction of the products of catecholamine oxidation.", "content": "EDTA prevents the photocatalyzed destruction of the products of catecholamine oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197066"} {"pmid": "4197067", "title": "Comparison of NCS solubilization and a wet combustion technique for 14 C measurement in dried biological tissues.", "content": "Comparison of NCS solubilization and a wet combustion technique for 14 C measurement in dried biological tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197067"} {"pmid": "4197068", "title": "THR (lopremone): psychobiological responses of normal women. I. Subjective experiences.", "content": "THR (lopremone): psychobiological responses of normal women. I. Subjective experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197068"} {"pmid": "4197070", "title": "Methaqualone withdrawal.", "content": "Methaqualone withdrawal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197070"} {"pmid": "4197069", "title": "THR (lopremone): psychobiological responses of normal women. II. Pituitary-thyroid responses.", "content": "THR (lopremone): psychobiological responses of normal women. II. Pituitary-thyroid responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197069"} {"pmid": "4197071", "title": "Toxicological and teratological studies of 4((5-chloro-2-oxo-3-benzothiazolinyl)acetyl)-1-piperazine ethanol hydrochloride (Tiaramide hydrochloride), an anti-inflammatory drug.", "content": "Toxicological and teratological studies of 4((5-chloro-2-oxo-3-benzothiazolinyl)acetyl)-1-piperazine ethanol hydrochloride (Tiaramide hydrochloride), an anti-inflammatory drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197071"} {"pmid": "4197073", "title": "Kinetic properties of microsomal UDP-glucuronyltransferase. Regulation by metal ions.", "content": "Kinetic properties of microsomal UDP-glucuronyltransferase. Regulation by metal ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197073"} {"pmid": "4197074", "title": "Organelle formation in the presence of a protease inhibitor.", "content": "Organelle formation in the presence of a protease inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197074"} {"pmid": "4197075", "title": "The use of buoyant density profiles in determining the length and spacing of repeated sequences in DNA.", "content": "The use of buoyant density profiles in determining the length and spacing of repeated sequences in DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197075"} {"pmid": "4197076", "title": "Membrane proteins of Rhodopseudomonas spheroides. IV. Characterization of chromatophore proteins.", "content": "Membrane proteins of Rhodopseudomonas spheroides. IV. Characterization of chromatophore proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197076"} {"pmid": "4197077", "title": "Uptake of calcium in chromaffin granules of bovine adrenal medulla stimulated in vitro.", "content": "Uptake of calcium in chromaffin granules of bovine adrenal medulla stimulated in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197077"} {"pmid": "4197078", "title": "Transcription of Tetrahymena mitochondrial DNA in vivo.", "content": "Transcription of Tetrahymena mitochondrial DNA in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197078"} {"pmid": "4197079", "title": "Presence of ergosterol in light-grown and dark-grown Euglena gracilis Z.", "content": "Presence of ergosterol in light-grown and dark-grown Euglena gracilis Z.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197079"} {"pmid": "4197080", "title": "Diamine oxidase in rabbit liver. 1. Assay conditions and subcellular localization.", "content": "Diamine oxidase in rabbit liver. 1. Assay conditions and subcellular localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197080"} {"pmid": "4197081", "title": "Diamine oxidase in rabbit liver. 2. Submicrosomal distribution.", "content": "Diamine oxidase in rabbit liver. 2. Submicrosomal distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197081"} {"pmid": "4197082", "title": "Dna synthesis in isolated HeLa nuclei. A system for continuation of replication in vivo.", "content": "Dna synthesis in isolated HeLa nuclei. A system for continuation of replication in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197082"} {"pmid": "4197084", "title": "Studies for the effect of some dietary factors prevalent in the oasis on the rate of growth and serum protein fractions of experimental animals.", "content": "Studies for the effect of some dietary factors prevalent in the oasis on the rate of growth and serum protein fractions of experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197084"} {"pmid": "4197085", "title": "Luetic deafness.", "content": "Luetic deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197085"} {"pmid": "4197086", "title": "A model for experimental vasomotor rhinitis.", "content": "A model for experimental vasomotor rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197086"} {"pmid": "4197090", "title": "Independent control of ribosomal gene replication in polytene chromosomes of Drosophila melanogaster.", "content": "Independent control of ribosomal gene replication in polytene chromosomes of Drosophila melanogaster. The saturation values for ribosomal RNA hybridization have been determined for DNA from diploid and polytene tissues of Drosophila melanogaster. These values have been measured in XO and XX larvae which have, respectively, one and two nucleolus organizers in the diploid chromosome set. The results show that (1) in diploid cells the ribosomal (r)DNA is present in amounts proportional to the number of nucleolus organizers, (2) in polytene cells the rDNA is under-replicated with respect to the euchromatic DNA, and (3) in polytene cells the amount of rDNA is independent of the diploid number of nucleolus organizers. These observations suggest that somatic variations in rDNA content may involve independent polytenization of the nucleolus organizer without change in the number of ribosomal cistrons per organizer. The independent polytenization of rDNA is proposed as the chromosomal explanation for the relative increase in rDNA in flies of the XO constitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197090"} {"pmid": "4197089", "title": "Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver.", "content": "Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver. The CO-difference spectrum of microsomes from rats treated with the polychlorinated biphenyls mixture, Aroclor 1254, has an absorption maximum at 448 nm. With ethylisocyananide as the ligand for reduced microsomes, Aroclor 1254 treatment causes a shift in the 455-nm peak to 453 nm and increases the ratio of absorbance of 455 nm to that at 430 nm from 0.53, obtained with untreated rats, to 1.24. These findings are similar to those seen in rats treated with the polycyclic hydrocarbon, 3-methylcholanthrene, but differ from those that characterize cytochrome P-450 in control or phenobarbital-treated rats. Aroclor 1254 treatment results in a tripling of cytochrome P-448 content and a 10-fold increase in benzo-[a]pyrene hydroxylation. However-unlike 3-methylcholanthrene, but like the phenobarbital type of inducing agents-Aroclor 1254 treatment causes a significant enhancement of ethylmorphine N-demethylase. These data suggest that Aroclor 1254-induced cytochrome P-448 may be catalytically different from the 3-methylcholanthrene-induced P-448 or that the hemoprotein(s) induced by Aroclor 1254 may be a mixture of cytochromes P-448 and P-450 exhibiting catalytic properties of both cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197089"} {"pmid": "4197092", "title": "Regulation of the -methylgalactoside transport system and the galatose-binding protein by the cell cycle of Escherichia coli.", "content": "Regulation of the -methylgalactoside transport system and the galatose-binding protein by the cell cycle of Escherichia coli. The synthesis of the periplasmic galactose-binding protein of E. coli is regulated by events occurring during its cell cycle, and proceeds in synchronized cells for only a short period after cell division is completed. Transport activity mediated by the beta-methylgalactoside transport system follows closely the synthesis pattern of the binding protein.A mutant, E. coli BUG-6, exhibits temperature-sensitive cell division [Reeve et al. (1970) J. Bacteriol. 104, 1052-1064], synthesizing galactose-binding protein at the permissive but not at the nonpermissive temperature. Galactose-binding protein synthesized at the permissive temperature is not degraded after the culture is shifted to the nonpermissive temperature. Polyacrylamide gel electrophoresis of the periplasmic proteins of BUG-6 grown at the permissive and nonpermissive temperatures suggests that several, but not all, periplasmic proteins are subject to the same regulatory control by the cell cycle as the galactose-binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197092"} {"pmid": "4197091", "title": "Conformational analysis of thyrotropin releasing factor.", "content": "Conformational analysis of thyrotropin releasing factor. Conformational energy calculations on thyrotropin releasing factor and on several of its analogues indicate that the central histidyl residue of the native molecule is in an extended conformation. Some derivatives (with a reduced biological activity) have an altered conformation. Since some substitutions leave the conformation unchanged but alter the biological activity, these substitutions must involve the sites responsible for binding of the hormone to its receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197091"} {"pmid": "4197093", "title": "Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli.", "content": "Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli. varphiX174 DNA-dependent dNMP incorporation is temperature-sensitive (ts) in extracts of uninfected E. coli dna A, B, C, D, E, and G ts strains. DNA synthesis can be restored in heat-inactivated extracts of various dna ts mutants by addition of extracts of wild-type or other dna ts mutants. A protein that restores activity to heat-inactivated extracts of dna G ts cells has been extensively purified. This protein has also been purified from dna G ts cells and is thermolabile when compared to the wild-type protein. The purified dna G protein has a molecular weight of about 60,000, is insensitive to N-ethylmaleimide, and binds poorly to DNA. It does not stimulate heat-inactivated crude extracts of dna B, C, D, or E ts cells and lacks detectable RNA and DNA polymerase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197093"} {"pmid": "4197095", "title": "Attempted induction of sarcoma in a Cape Chacma baboon with the Snyder-Theilen feline sarcoma virus.", "content": "Attempted induction of sarcoma in a Cape Chacma baboon with the Snyder-Theilen feline sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197095"} {"pmid": "4197104", "title": "Features of cerebellar morphology and organization.", "content": "Features of cerebellar morphology and organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197104"} {"pmid": "4197105", "title": "Multiple sclerosis: immunoglobulin alterations related to different clinical parameters.", "content": "Multiple sclerosis: immunoglobulin alterations related to different clinical parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197105"} {"pmid": "4197106", "title": "The innervation of the cerebral arteries in the monkey.", "content": "The innervation of the cerebral arteries in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197106"} {"pmid": "4197107", "title": "Meningococcal infections.", "content": "Meningococcal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197107"} {"pmid": "4197108", "title": "Capillary basement membranes and diabetic microangiopathy.", "content": "Capillary basement membranes and diabetic microangiopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197108"} {"pmid": "4197109", "title": "Total parenteral nutrition.", "content": "Total parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197109"} {"pmid": "4197110", "title": "Axon diameter and myelin thickness. Unusual relationships in dorsal root ganglia.", "content": "Axon diameter and myelin thickness. Unusual relationships in dorsal root ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197110"} {"pmid": "4197121", "title": "Study of the extracellular polysaccharides produced by a blue-green alga, Anabaena flos-aquae A-37.", "content": "Study of the extracellular polysaccharides produced by a blue-green alga, Anabaena flos-aquae A-37.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197121"} {"pmid": "4197123", "title": "Purification and properties of two forms of staphylococcal toxin.", "content": "Purification and properties of two forms of staphylococcal toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197123"} {"pmid": "4197125", "title": "Drug-induced reinstatement of amphetamine self-administration behaviour in monkeys.", "content": "Drug-induced reinstatement of amphetamine self-administration behaviour in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197125"} {"pmid": "4197124", "title": "Water and ions in muscles and model systems.", "content": "Water and ions in muscles and model systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197124"} {"pmid": "4197128", "title": "Fundamentals of infant resuscitation.", "content": "Fundamentals of infant resuscitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197128"} {"pmid": "4197129", "title": "Problems in the determination of polychlorinated biphenyls.", "content": "Problems in the determination of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197129"} {"pmid": "4197130", "title": "Decrease in pulmonary diffusing capacity during lipid infusion in healthy men.", "content": "Decrease in pulmonary diffusing capacity during lipid infusion in healthy men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197130"} {"pmid": "4197131", "title": "The interaction of radioactive initiation factor IF-2 with ribosomes during initiation of protein synthesis.", "content": "The interaction of radioactive initiation factor IF-2 with ribosomes during initiation of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197131"} {"pmid": "4197133", "title": "Subunit heterogeneity of thyroglobulin.", "content": "Subunit heterogeneity of thyroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197133"} {"pmid": "4197132", "title": "The subunits of human pituitary thyroid-stimulating hormone. Isolation, properties, and composition.", "content": "The subunits of human pituitary thyroid-stimulating hormone. Isolation, properties, and composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197132"} {"pmid": "4197135", "title": "The complete development of the sporogonous stages of Hepatozoon rarefaciens cultured in a Culex pipiens cell line.", "content": "The complete development of the sporogonous stages of Hepatozoon rarefaciens cultured in a Culex pipiens cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197135"} {"pmid": "4197134", "title": "Meningonema peruzzii gen. et sp. n. (Nematoda: Filarioidea) from the central nervous system of African monkeys.", "content": "Meningonema peruzzii gen. et sp. n. (Nematoda: Filarioidea) from the central nervous system of African monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197134"} {"pmid": "4197136", "title": "Sarcocystis in dogs and its probable transmission from cattle.", "content": "Sarcocystis in dogs and its probable transmission from cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197136"} {"pmid": "4197138", "title": "Evolving concepts of thyroid function.", "content": "Evolving concepts of thyroid function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197138"} {"pmid": "4197139", "title": "The malabsorption syndrome.", "content": "The malabsorption syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197139"} {"pmid": "4197140", "title": "Action of levallorphan: macromolecular synthesis and cell division.", "content": "Action of levallorphan: macromolecular synthesis and cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197140"} {"pmid": "4197141", "title": "Analogues of fusaric (5-butylpicolinic) acid as potent inhibitors of dopamine -hydroxylase.", "content": "Analogues of fusaric (5-butylpicolinic) acid as potent inhibitors of dopamine -hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197141"} {"pmid": "4197142", "title": "Levodopa and melanoma.", "content": "Levodopa and melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197142"} {"pmid": "4197144", "title": "A new understanding of hepatitis.", "content": "A new understanding of hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197144"} {"pmid": "4197148", "title": "Somatic evoked response recording: an adequate test of deafferentation?", "content": "Somatic evoked response recording: an adequate test of deafferentation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197148"} {"pmid": "4197147", "title": "Induction of mating behavior in rats by luteinizing hormone-releasing factor.", "content": "Induction of mating behavior in rats by luteinizing hormone-releasing factor. Ovariectomized female rats treated with estrogen, in dosages too low to provoke mating, displayed this behavior when given subcutaneous injections of synthetic luteinizing hormone-releasing factor (LRF) 48 hours later. Two hours after the injection of LRF, components of female sexual behavior appeared. The lordosis reflex followed mounting by the male, and darting and hopping behavior was quite prevalent. On the other hand, treatment with estrogen followed by luteinizing hormone, follicle-stimulating hormone, or thyrotropin-releasing factor did not induce copulatory behavior. The results suggest that LRF may play a role in induction of mating behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197147"} {"pmid": "4197151", "title": "Electron microscopic study of the endothelium of stored and cryopreserved monkey corneas.", "content": "Electron microscopic study of the endothelium of stored and cryopreserved monkey corneas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197151"} {"pmid": "4197152", "title": "Osteomyelitis in hemodialysis patients.", "content": "Osteomyelitis in hemodialysis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197152"} {"pmid": "4197153", "title": "Diabetic ketoacidosis associated with mumps virus infection. Occurrence in a patient with macroamylasemia.", "content": "Diabetic ketoacidosis associated with mumps virus infection. Occurrence in a patient with macroamylasemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197153"} {"pmid": "4197155", "title": "Bilateral hilar adenopathy.", "content": "Bilateral hilar adenopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197155"} {"pmid": "4197154", "title": "How effective will national health insurance be?", "content": "How effective will national health insurance be?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197154"} {"pmid": "4197156", "title": "Immunochemical studies of AMP:pyrophosphate phosphoribosyltransferase from normal and Lesch-Nyhan subjects.", "content": "Immunochemical studies of AMP:pyrophosphate phosphoribosyltransferase from normal and Lesch-Nyhan subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197156"} {"pmid": "4197157", "title": "Involvement of a carboxyl group in the active site of Bacillus cereus 569-H penicillinse ( -lactamase I).", "content": "Involvement of a carboxyl group in the active site of Bacillus cereus 569-H penicillinse ( -lactamase I).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197157"} {"pmid": "4197158", "title": "Inhibition of phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase by uridine diphosphate N-acetylmuramyl peptides.", "content": "Inhibition of phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase by uridine diphosphate N-acetylmuramyl peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197158"} {"pmid": "4197159", "title": "The effect of temperature, age and density of gametocytes, and changes in gas composition on exflagellation of Leucocytozoon simondi.", "content": "The effect of temperature, age and density of gametocytes, and changes in gas composition on exflagellation of Leucocytozoon simondi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197159"} {"pmid": "4197160", "title": "The fine structure of Leucocytozoon simondi. VI. Hepatic schizogony.", "content": "The fine structure of Leucocytozoon simondi. VI. Hepatic schizogony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197160"} {"pmid": "4197161", "title": "Corynebacterium diphtheriae in a patient with multiple trauma.", "content": "Corynebacterium diphtheriae in a patient with multiple trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197161"} {"pmid": "4197163", "title": "A clinical index of disability due to chronic asthma tested during a trial of cromolyn sodium treatment.", "content": "A clinical index of disability due to chronic asthma tested during a trial of cromolyn sodium treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197163"} {"pmid": "4197162", "title": "Short- and long-term prophylaxis with cromolyn sodium in chronic asthma.", "content": "Short- and long-term prophylaxis with cromolyn sodium in chronic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197162"} {"pmid": "4197164", "title": "An evaluation of bacterial contamination of ventilator humidifying systems.", "content": "An evaluation of bacterial contamination of ventilator humidifying systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197164"} {"pmid": "4197165", "title": "Replication pattern and quinacrine fluorescence of the chromosomes of a CV-1-derived African green monkey cell line.", "content": "Replication pattern and quinacrine fluorescence of the chromosomes of a CV-1-derived African green monkey cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197165"} {"pmid": "4197166", "title": "Complementation analysis of male fertility among the segregation distorter chromosomes of Drosophila melanogaster.", "content": "Complementation analysis of male fertility among the segregation distorter chromosomes of Drosophila melanogaster. The fecundities of 55 genotypes of the form SD(i)/SD(j) generated by 11 different SD chromosomes have been examined. Five of the genotypes are lethal The fecundities of the rest fall into a pattern of fertility and sterility that is highly suggestive of intracistronic complementation. The complementation leading to male fertility is only partial complementation: the fecundity of most fertile genotypes is less than half that of controls. The three components of the SD system, the Sd locus, the Ac locus, and the modifiers in 2R, were examined separately, and it appears that the complementation is a phenomenon associated with the Sd locus. A hypothesis of the molecular events involved in segregation distortion is formulated in the light of these observations. The model is based on the assumption that the Sd locus produces a multimeric molecule that regulates the activity of the Ac(=Rsp) locus during spermatogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197166"} {"pmid": "4197167", "title": "Meiotic behavior of asymmetric dyads in the male Drosophila.", "content": "Meiotic behavior of asymmetric dyads in the male Drosophila. Crossing over in the interstitial region of the heterozygous V(4) translocation in Drosophila melanogaster generates asymmetric dyads each consisting of a shorter and a longer chromatid. It was shown previously that in the female the shorter is recovered preferentially (Zimmering 1955); the present work suggests that the same occurs in the male as well. The mechanism in the female is envisioned as involving the non-random inclusion of the shorter chromatid into the functional egg (Novitski 1951); in the male, the two formal possibilities appear to be (1) that some proportion of sperm carrying the longer chromatid derived from an asymmetric dyad undergoes dysfunction, or (2) the longer chromatid is preferentially included into regularly-produced nonfunctional sperm, the nonfunctionality set up at the second division and distinguishing second division daughter cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197167"} {"pmid": "4197168", "title": "Analysis of carbamates as fluorescent 1-dimethylamino-naphthalene-5-sulfonate esters.", "content": "Analysis of carbamates as fluorescent 1-dimethylamino-naphthalene-5-sulfonate esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197168"} {"pmid": "4197169", "title": "Trace analysis and fundamental studies by plasma chromatography.", "content": "Trace analysis and fundamental studies by plasma chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197169"} {"pmid": "4197170", "title": "Culture for gonorrhea in asymptomatic college women.", "content": "Culture for gonorrhea in asymptomatic college women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197170"} {"pmid": "4197177", "title": "Spectral sensitivity in primates: a comparative study.", "content": "Spectral sensitivity in primates: a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197177"} {"pmid": "4197182", "title": "Excretion of urate by the kidneys of Cebus monkeys: a micropuncture study.", "content": "Excretion of urate by the kidneys of Cebus monkeys: a micropuncture study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197182"} {"pmid": "4197184", "title": "Uricosuric effect of benziodarone in man and laboratory animals: a comparative study.", "content": "Uricosuric effect of benziodarone in man and laboratory animals: a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197184"} {"pmid": "4197183", "title": "Plasma kallikrein-kinin system in nonmammalian blood: evolutionary aspects.", "content": "Plasma kallikrein-kinin system in nonmammalian blood: evolutionary aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197183"} {"pmid": "4197185", "title": "Nature of the uricosuric action of benziodarone.", "content": "Nature of the uricosuric action of benziodarone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197185"} {"pmid": "4197186", "title": "Changes of plasma glucose and insulin during defense reactions in monkeys.", "content": "Changes of plasma glucose and insulin during defense reactions in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197186"} {"pmid": "4197188", "title": "Recent advances in the physiology and pathophysiology of potassium excretion.", "content": "Recent advances in the physiology and pathophysiology of potassium excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197188"} {"pmid": "4197189", "title": "Release of thyroid stimulating hormone from chick anterior pituitary glands by thyrotropin releasing hormone (TRH).", "content": "Release of thyroid stimulating hormone from chick anterior pituitary glands by thyrotropin releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197189"} {"pmid": "4197190", "title": "Polygammaglutamyl metabolites of methotrexate.", "content": "Polygammaglutamyl metabolites of methotrexate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197190"} {"pmid": "4197191", "title": "A novel technique for the preparation of transport-active membrane vesicles from Pseudomonas aeruginosa: observations on gluconate transport.", "content": "A novel technique for the preparation of transport-active membrane vesicles from Pseudomonas aeruginosa: observations on gluconate transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197191"} {"pmid": "4197192", "title": "The synaptic organization in the inferior pulvinar of the rhesus monkey (Macaca mulatta).", "content": "The synaptic organization in the inferior pulvinar of the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197192"} {"pmid": "4197193", "title": "Sympathomimetic anesthetics.", "content": "Sympathomimetic anesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197193"} {"pmid": "4197194", "title": "Radioimmunoassay of testosterone during fetal development of the rhesus monkey.", "content": "Radioimmunoassay of testosterone during fetal development of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197194"} {"pmid": "4197195", "title": "Comparison of baboon and human placental lactogens.", "content": "Comparison of baboon and human placental lactogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197195"} {"pmid": "4197187", "title": "Suction flow drainage in head and neck surgery. A new principle for postoperative suction drainage.", "content": "Suction flow drainage in head and neck surgery. A new principle for postoperative suction drainage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197187"} {"pmid": "4197199", "title": "Prenylamine lactate in angina pectoris.", "content": "Prenylamine lactate in angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197199"} {"pmid": "4197200", "title": "Effect of nitrogen mustard and corticoids on experimentally produced villonodular synovitis.", "content": "Effect of nitrogen mustard and corticoids on experimentally produced villonodular synovitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197200"} {"pmid": "4197202", "title": "Shigellosis in rhesus monkeys in quarantine.", "content": "Shigellosis in rhesus monkeys in quarantine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197202"} {"pmid": "4197201", "title": "Dimethyl sulfoxide in the treatment of experimental brain compression.", "content": "Dimethyl sulfoxide in the treatment of experimental brain compression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197201"} {"pmid": "4197203", "title": "Use of CT1341 anaesthetic (\"Saffan\") in monkeys.", "content": "Use of CT1341 anaesthetic (\"Saffan\") in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197203"} {"pmid": "4197204", "title": "The cerebral autonomic nervous system. A proposed physiologic function and pathophysiologic response in subarachnoid hemorrhage and in focal cerebral ischemia.", "content": "The cerebral autonomic nervous system. A proposed physiologic function and pathophysiologic response in subarachnoid hemorrhage and in focal cerebral ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197204"} {"pmid": "4197207", "title": "Correlation between lethality and DNA single-strand breaks in Bacillus subtilis cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.", "content": "Correlation between lethality and DNA single-strand breaks in Bacillus subtilis cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197207"} {"pmid": "4197208", "title": "Central neurogenic control of cerebral circulation. Effects of intravertebral injection of pyrithioxin on cerebral blood flow and metabolism.", "content": "Central neurogenic control of cerebral circulation. Effects of intravertebral injection of pyrithioxin on cerebral blood flow and metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197208"} {"pmid": "4197210", "title": "Pulp capping in monkeys with a calcium-hydroxide compound, an antibiotic, and a polycarboxylate cement.", "content": "Pulp capping in monkeys with a calcium-hydroxide compound, an antibiotic, and a polycarboxylate cement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197210"} {"pmid": "4197209", "title": "Myasthenia gravis. Cellular response to basic myelin protein compared with cellular and humoral immunity to muscle antigens.", "content": "Myasthenia gravis. Cellular response to basic myelin protein compared with cellular and humoral immunity to muscle antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197209"} {"pmid": "4197213", "title": "Mechanisms of cholesterol accumulation in atherosclerotic lesions.", "content": "Mechanisms of cholesterol accumulation in atherosclerotic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197213"} {"pmid": "4197215", "title": "Nutrition and the liver.", "content": "Nutrition and the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197215"} {"pmid": "4197216", "title": "Growth and growth hormone in protein calorie malnutrition.", "content": "Growth and growth hormone in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197216"} {"pmid": "4197220", "title": "Serological analysis of wheat striate mosaic virus and its soluble antigen.", "content": "Serological analysis of wheat striate mosaic virus and its soluble antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197220"} {"pmid": "4197221", "title": "The role of sensitizing antibody in the neutralization of equine arteritis virus by complement or anti-IgG serum.", "content": "The role of sensitizing antibody in the neutralization of equine arteritis virus by complement or anti-IgG serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197221"} {"pmid": "4197222", "title": "The fate of sensitized equine arteritis virus following neutralization by complement of anti-IgG serum.", "content": "The fate of sensitized equine arteritis virus following neutralization by complement of anti-IgG serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197222"} {"pmid": "4197223", "title": "Viral RNA synthesis in measles virus-infected cells.", "content": "Viral RNA synthesis in measles virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197223"} {"pmid": "4197226", "title": "Technical solution of the problem of investigation of instrumental conditioned reflexes with intragastric reinforcement.", "content": "Technical solution of the problem of investigation of instrumental conditioned reflexes with intragastric reinforcement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197226"} {"pmid": "4197227", "title": "Plasma and red blood cell amino acids of Egyptian children suffering from protein--calorie malnutrition.", "content": "Plasma and red blood cell amino acids of Egyptian children suffering from protein--calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197227"} {"pmid": "4197228", "title": "Evaluation of small-scale nutrition programs.", "content": "Evaluation of small-scale nutrition programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197228"} {"pmid": "4197229", "title": "Mode of action of rifampin on mycobacteria. I. Electron microscopic study of the effect of rifampin on Mycobacterium tuberculosis.", "content": "Mode of action of rifampin on mycobacteria. I. Electron microscopic study of the effect of rifampin on Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197229"} {"pmid": "4197230", "title": "Correlation of in vitro and in vivo kinetics with clinical use of isoniazid, ethambutol, and rifampin.", "content": "Correlation of in vitro and in vivo kinetics with clinical use of isoniazid, ethambutol, and rifampin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197230"} {"pmid": "4197231", "title": "The relative immunogenicity of virulent and attenuated strains of tubercle bacilli.", "content": "The relative immunogenicity of virulent and attenuated strains of tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197231"} {"pmid": "4197232", "title": "The fate of virulent and attenuated Mycobacteria in guinea pigs infected by the respiratory route.", "content": "The fate of virulent and attenuated Mycobacteria in guinea pigs infected by the respiratory route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197232"} {"pmid": "4197233", "title": "Clearance and inactivation of the vegetative and spore forms of Bacillus subtilis Var niger in rat lungs.", "content": "Clearance and inactivation of the vegetative and spore forms of Bacillus subtilis Var niger in rat lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197233"} {"pmid": "4197234", "title": "Incidence of pulmonary tuberculosis.", "content": "Incidence of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197234"} {"pmid": "4197236", "title": "A note on the toxic effects of tricresylphosphate on spinal ganglion of slow loris (Nycticebus cougang cougang).", "content": "A note on the toxic effects of tricresylphosphate on spinal ganglion of slow loris (Nycticebus cougang cougang).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197236"} {"pmid": "4197237", "title": "Wheat leaf RNA polymerases. 3. Purification of the soluble RNA polymerase.", "content": "Wheat leaf RNA polymerases. 3. Purification of the soluble RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197237"} {"pmid": "4197238", "title": "Permeability of the duodenum of the toad to non-electrolytes.", "content": "Permeability of the duodenum of the toad to non-electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197238"} {"pmid": "4197240", "title": "Australia (hepatitis-associated) antigen in patients attending a venereal disease clinic.", "content": "Australia (hepatitis-associated) antigen in patients attending a venereal disease clinic. A total of 1,650 patients attending the venereal disease department at St. Mary's Hospital, London, have been tested for Australia antigen. Twenty-three positive results were obtained, or 1.39%, which is more than 10 times the rate noted by others in blood donor populations in the U.K. and U.S.A. The positive rates among female patients and European male heterosexual patients were 0.36% and 0.19% respectively. High rates were obtained for homosexual patients (3.8%) and non-European heterosexual patients (3.1%). The reasons for the higher rates found in these groups merit further study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197240"} {"pmid": "4197241", "title": "Administration of disodium cromoglycate to young children.", "content": "Administration of disodium cromoglycate to young children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197241"} {"pmid": "4197239", "title": "Prognosis of acute renal failure.", "content": "Prognosis of acute renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197239"} {"pmid": "4197242", "title": "Characterization and partial purification of -hydroxybutyrate dehydrogenase from sporulating cells of Bacillus cereus T.", "content": "Characterization and partial purification of -hydroxybutyrate dehydrogenase from sporulating cells of Bacillus cereus T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197242"} {"pmid": "4197243", "title": "A cluster of mutations determining erythromycin resistance in Bacillus subtilis.", "content": "A cluster of mutations determining erythromycin resistance in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197243"} {"pmid": "4197245", "title": "The immunological analysis of soluble human leukemia associated antigens.", "content": "The immunological analysis of soluble human leukemia associated antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197245"} {"pmid": "4197244", "title": "Extracellular carbohydrate antigens from some non-pathogenic Neisseria species.", "content": "Extracellular carbohydrate antigens from some non-pathogenic Neisseria species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197244"} {"pmid": "4197246", "title": "Immunological reactions of Mycobacterium leprae and Mycobacterium lepraemurium grown in cayman.", "content": "Immunological reactions of Mycobacterium leprae and Mycobacterium lepraemurium grown in cayman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197246"} {"pmid": "4197247", "title": "Improved techniques for assessment of plasma lipoprotein patterns. I. Precipitation in gels after electrophoresis with polyanionic compounds.", "content": "Improved techniques for assessment of plasma lipoprotein patterns. I. Precipitation in gels after electrophoresis with polyanionic compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197247"} {"pmid": "4197248", "title": "Immunochemical identification of prostatic tissue-specific acid phosphatase.", "content": "Immunochemical identification of prostatic tissue-specific acid phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197248"} {"pmid": "4197249", "title": "Immunochemical identification of prostatic tissue-specific acid phosphatase.", "content": "Immunochemical identification of prostatic tissue-specific acid phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197249"} {"pmid": "4197250", "title": "RIA: an historical note.", "content": "RIA: an historical note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197250"} {"pmid": "4197251", "title": "Objective assessment of a bronchodilator drug combination in asthmatic outpatients.", "content": "Objective assessment of a bronchodilator drug combination in asthmatic outpatients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197251"} {"pmid": "4197252", "title": "Lidoflazine and angina pectoris: a placebo-controlled double-blind study.", "content": "Lidoflazine and angina pectoris: a placebo-controlled double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197252"} {"pmid": "4197253", "title": "A study of the selectivity of action of oxyphencyclimine hydrochloride on gastric secretion. (selectivity of oxyphencyclimine).", "content": "A study of the selectivity of action of oxyphencyclimine hydrochloride on gastric secretion. (selectivity of oxyphencyclimine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197253"} {"pmid": "4197255", "title": "A long-term follow-up of fluphenazine enanthate treatment.", "content": "A long-term follow-up of fluphenazine enanthate treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197255"} {"pmid": "4197254", "title": "Effects of hydrochlorothiazide in hypertensive patients and the need for potassium supplementation.", "content": "Effects of hydrochlorothiazide in hypertensive patients and the need for potassium supplementation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197254"} {"pmid": "4197256", "title": "Milipertine: an early evaluation in severely ill schizophrenics.", "content": "Milipertine: an early evaluation in severely ill schizophrenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197256"} {"pmid": "4197257", "title": "SCH-12041 in the treatment of acute schizophrenic patients.", "content": "SCH-12041 in the treatment of acute schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197257"} {"pmid": "4197258", "title": "A double-blind comparison of AL-1021 and chlorpromazine in hospitalized schizophrenics.", "content": "A double-blind comparison of AL-1021 and chlorpromazine in hospitalized schizophrenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197258"} {"pmid": "4197260", "title": "In vitro studies of trans- and intraepithelial potentials of the cornea.", "content": "In vitro studies of trans- and intraepithelial potentials of the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197260"} {"pmid": "4197261", "title": "Recent studies on the nature and function of the corneal endothelial barrier.", "content": "Recent studies on the nature and function of the corneal endothelial barrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197261"} {"pmid": "4197262", "title": "Kinines and pain in \"dry socket\".", "content": "Kinines and pain in \"dry socket\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197262"} {"pmid": "4197263", "title": "Renal viability and oxygen consumption measurements during preservation.", "content": "Renal viability and oxygen consumption measurements during preservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197263"} {"pmid": "4197264", "title": "Glutamic acid decarboxylase in spores of Bacillus megaterium and its possible involvement in spore germination.", "content": "Glutamic acid decarboxylase in spores of Bacillus megaterium and its possible involvement in spore germination. Spores of Bacillus megaterium were examined for glutamic acid decarboxylase (GAD). Although dormant spores showed no GAD activity, spores given sonic treatment and heat-activated spores had high activities when assayed for this enzyme. Several parameters of GAD in heat-activated spores were examined. The effects of KCN, NaN(3), 2,4-dinitrophenol, and KF on GAD activity were examined. Only KCN was an effective inhibitor of GAD activity in heated spores and was also shown to be the only effective inhibitor of GAD activity in vegetative bacteria. Similar patterns of inhibition were obtained with GAD activity and with spore germination, KCN being the only effective inhibitor of both, although at different concentrations. Spore GAD activity in heat-activated spores showed a loss with storage at 4 C; on the other hand, storage at 25 C was not accompanied by a loss, but, to the contrary, showed an increase in GAD activity of about 30%. A comparison of GAD activity at different times during germination, growth, and sporulation showed it to be highest in freshly germinated spores. Although vegetative cells contained GAD activity, the level in log-phase cells was approximately one-half the level obtained with freshly germinated spores. Heat-activated mutant spores with a requirement of gamma-aminobutyric acid for germination gave no GAD activity. GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197264"} {"pmid": "4197265", "title": "Deoxyribonucleic acid synthesis and deoxynucleotide metabolism during bacterial spore germination.", "content": "Deoxyribonucleic acid synthesis and deoxynucleotide metabolism during bacterial spore germination. Deoxyribonucleic acid (DNA) synthesis during germination of Bacillus megaterium spores takes place in two stages. In stage I (0-55 min) DNA synthesis is slow and there is no detectable net synthesis, whereas in stage II (from 55 min on) the rate of synthesis is much faster and net DNA synthesis occurs. Deoxyribonucleotide pool sizes match the rates of DNA synthesis in stages I and II. The level of deoxyribonucleotide triphosphates is not correlated with the level of deoxyribonucleotide kinases, but rather with that of ribonucleotide reductase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197265"} {"pmid": "4197266", "title": "Location of the SPO2 attachment site and the bryamycin resistance marker on the Bacillus subtilis chromosome.", "content": "Location of the SPO2 attachment site and the bryamycin resistance marker on the Bacillus subtilis chromosome. The attachment site on the Bacillus subtilis chromosome for the lysogenic bacteriophage SPO2 has been mapped by PBS1-mediated transduction and was found to be between spc-2 and lin-2, showing 90% linkage to the former and 30% linkage to the latter marker. In the course of these studies the bry-2 marker was mapped between the cysA14 and str-1 loci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197266"} {"pmid": "4197267", "title": "Osmotic behavior of bacterial protoplasts: temperature effects.", "content": "Osmotic behavior of bacterial protoplasts: temperature effects. Among protoplasts released from cells of Bacillus megaterium grown at 20, 30, or 37 C, osmotic swelling in NaCl solution at a given external osmotic pressure was greatest for protoplasts from cells grown at 20 C and least for protoplasts from cells grown at 37 C. Protoplasts from cells grown at lower temperaturs were also less stable to osmotic shock and lysed at higher external osmotic pressures than did protoplasts from cells grown at higher temperatures. But for cells grown at any one temperature, osmotic stabilization was itself temperature dependent so that the higher the ambient incubation temperature, the higher the osmotic pressure needed to prevent lysis of a given fraction of the input protoplast population. However, comparison of the osmotic stability of protoplasts from cells grown at different temperatures at various ambient incubation temperatures revealed that, except at 5 C where no differences were discerned, protoplasts from cells grown at lower temperatures still lysed at higher osmotic pressures than did those from cells grown at higher temperatures. The apparent internal osmolality (28 to 31 atm) did not vary significantly among whole cells from the three growth temperatures. Therefore, the observed differences in osmotic behavior could not be attributed to changes in internal osmotic pressure. Rather, it seemed likely that the differences were due to changes in membrane properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197267"} {"pmid": "4197268", "title": "Isolation of two acetyl esterases from extracts of Bacillus subtilis.", "content": "Isolation of two acetyl esterases from extracts of Bacillus subtilis. Acrylamide gel electrophoresis of crude cellular extracts of Bacillus subtilis revealed the presence of two acetyl esterases. Esterase A, the slower migrating enzyme, was found to be present in both vegetative and sporulating cells, whereas esterase B activity was more abundant after exponential growth ceased. Both esterases were present in the supernatant fraction of lysed spheroplasts and in a disrupted spore preparation. Of four pleiotropic asporogenous mutants tested, three exhibited decreased esterase B activity. Esterases A and B were partially purified by differential precipitation and co-chromatographed on diethylaminoethyl (DEAE)-cellulose (pH 7.5) and DEAE-Sephadex (pH 8.5). By employing gel filtration chromatography, the two esterases were separated, and molecular weights of 160,000 and 51,000 were estimated for esterases A and B, respectively. Esterase A was further purified to electrophoretic homogeneity by differential heating and preparative starch block electrophoresis. Sodium dodecyl sulfate-acrylamide gel electrophoresis of purified esterase A yielded a single protein band with a molecular weight of 31,000. The pI values of esterases A and B were determined to be 6.4 and 5.4, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197268"} {"pmid": "4197269", "title": "Oxygen toxicity and the superoxide dismutase.", "content": "Oxygen toxicity and the superoxide dismutase. Oxygen caused an increase in the amount of superoxide dismutase in Escherichia coli B but not in Bacillus subtilis. E. coli B cells, induced by growth under 100% O(2), were much more resistant to the lethal effects of 20 atm of O(2) than were cells which contained the low uninduced level of this enzyme. In contrast, B. subtilis, which could not respond to O(2) by increasing its content of superoxide dismutase, remained equally sensitive to hyperbaric O(2) whether grown under 100% O(2) or areobically. The catalase in these organisms exhibited a reciprocal response to oxygen. Thus, the catalase of E. coli B was not induced by O(2), whereas that of B. subtilis was so induced. These results are consistent with the view that superoxide dismutase is an important component of the defenses of these organisms against the toxicity of oxygen, whereas their catalases are of secondary importance in this respect. The ability of streptonigrin to generate O(2) (-), by a cycle of reduction followed by spontaneous reoxidation, has been verified in vitro. It is further observed that E. coli B which contain the high induced level of superoxide dismutase were more resistant to the lethality of this antibiotic, in the presence of oxygen, than were E. coli B which contained the low uninduced level of this enzyme. This difference between induced and uninduced cells was eliminated by the removal of O(2). These results are consistent with the proposal that the enhanced lethality of streptonigrin under aerobic conditions may relate to its in vivo generation of O(2) (-) by a cycle of reduction and spontaneous reoxidation. In toto, these observations lend support to the hypothesis that O(2) (-) is an important agent of oxygen toxicity and that superoxide dismutase functions to blunt the threat posed by this reactive radical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197269"} {"pmid": "4197270", "title": "Measurement of the cyanophycin granule polypeptide contained in the blue-green alga Anabaena cylindrica.", "content": "Measurement of the cyanophycin granule polypeptide contained in the blue-green alga Anabaena cylindrica. An assay was developed to determine the amount of cyanophycin granules in blue-green algae. The amount of this polypeptide in cells of Anabaena cylindrica was measured as a function of culture age and was compared with changes in other proteinaceous cellular components. The data presented support the notion that the cyanophycin granule is a cellular nitrogen reserve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197270"} {"pmid": "4197272", "title": "Use of constructed double mutants for determining the temporal order of expression of sporulation genes in Bacillus subtilis.", "content": "Use of constructed double mutants for determining the temporal order of expression of sporulation genes in Bacillus subtilis. Double mutants containing two Spo mutations concerned with different stages of sporulation were constructed. In these, the phenotype that is exhibited is that of the earlier sporulation block. The same procedure was applied to sporulation mutants damaged in the same stage of development. The results provide a basis for placing in a temporal order different mutations concerned in stage II and stage IV of spore development. In general, the order indicated by the phenotypes of the double mutants is in agreement with the order derived on biochemical grounds. Double oligosporogenous mutants have also been constructed. Their sporulation incidence is roughly equal to the product of the incidences of the parent strains, idicating that separate factors are involved in overcoming each oligosporogenous block. The number of dependent sequential steps in sporulation is estimated as not less than about 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197272"} {"pmid": "4197271", "title": "Mapping of asporogenous mutations of Bacillus subtilis: a minimum estimate of the number of sporeulation operons.", "content": "Mapping of asporogenous mutations of Bacillus subtilis: a minimum estimate of the number of sporeulation operons. Sporulation-specific mutations in Bacillus subtilis have been mapped by transduction and transformation. The mutations caused blocks at stages 0, II, III, and IV of sporulation; more than one phenotype was found for each of these stages. On the basis of the criteria used to define a sporulation operon, a minimum estimate could be made of the number of operons activated during sporulation. Nine operons were identified for stage 0, eight for stage II, five for stage III, and six for stage IV. It is probable that several of these 28 operons are activated in groups so that the number of steps in the dependent sequence of sporulation events should turn out to be less than the number of operons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197271"} {"pmid": "4197273", "title": "Surface structure of gliding bacteria after freeze-etching.", "content": "Surface structure of gliding bacteria after freeze-etching. Ultrastructural studies of gliding bacteria demonstrate 10- to 11-nm beads on the inner surface of the outer bilayer of Cytophaga columnaris. These were not found in Myxococcus xanthus. On treatment with glutaraldehyde and ethanol, the beads appear in linear arrays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197273"} {"pmid": "4197275", "title": "Prophylactic therapy of angina pectoris with organic nitrates: relationship of drug efficacy and clinical experimental design.", "content": "Prophylactic therapy of angina pectoris with organic nitrates: relationship of drug efficacy and clinical experimental design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197275"} {"pmid": "4197276", "title": "Pathogenesis of Marek's disease: early distribution of virus and viral antigens in infected chickens.", "content": "Pathogenesis of Marek's disease: early distribution of virus and viral antigens in infected chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197276"} {"pmid": "4197274", "title": "Extractable lipids of gram-negative marine bacteria: phospholipid composition.", "content": "Extractable lipids of gram-negative marine bacteria: phospholipid composition. Phospholipid compositions of 20 strains of marine and estuarine bacteria were determined. Results showed that phospholipids of marine bacteria differed very little from those of nonmarine organisms with phosphatidylethanolamine, phosphatidylglycerol, and diphosphatidylglycerol being the predominant phospholipids in all strains examined. Lyso-phosphatidylethanolamine occurred in significant quantities among a number of the marine bacteria, and two of the isolates contained significant quantities of poly-beta-hydroxybutyrate. Effects of age and growth temperature on the phospholipid composition were also investigated. It is suggested that phylogenetic relationships among bacteria may be correlated with phospholipid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197274"} {"pmid": "4197278", "title": "Effects of d-amphetamine on schedule-controlled key pressing and drinking in the chimpanzee.", "content": "Effects of d-amphetamine on schedule-controlled key pressing and drinking in the chimpanzee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197278"} {"pmid": "4197277", "title": "Urinary metabolic profiles for choosing test animals for chronic toxicity studies: application to naproxen.", "content": "Urinary metabolic profiles for choosing test animals for chronic toxicity studies: application to naproxen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197277"} {"pmid": "4197279", "title": "Pharmacology of cyanate. I. General effects on experimental animals.", "content": "Pharmacology of cyanate. I. General effects on experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197279"} {"pmid": "4197281", "title": "The long-stay hospital--a modern concept.", "content": "The long-stay hospital--a modern concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197281"} {"pmid": "4197285", "title": "Metaplastic bone formation in the lung.", "content": "Metaplastic bone formation in the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197285"} {"pmid": "4197284", "title": "On the application of knowledge to the patient with genetic disease.", "content": "On the application of knowledge to the patient with genetic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197284"} {"pmid": "4197287", "title": "Encephalopathy and fatty degeneration of viscera: Reye's syndrome.", "content": "Encephalopathy and fatty degeneration of viscera: Reye's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197287"} {"pmid": "4197290", "title": "Cancer and the evolution of species: a ransom.", "content": "Cancer and the evolution of species: a ransom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197290"} {"pmid": "4197292", "title": "Subnuclear redistribution of DNA species in confluent and growing mammalian cells.", "content": "Subnuclear redistribution of DNA species in confluent and growing mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197292"} {"pmid": "4197291", "title": "The skin in disseminated intravascular coagulation. Prospective analysis of thirty-six cases.", "content": "The skin in disseminated intravascular coagulation. Prospective analysis of thirty-six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197291"} {"pmid": "4197293", "title": "Determination of the binding of thyroxine to plasma proteins by competitive protein-binding analysis.", "content": "Determination of the binding of thyroxine to plasma proteins by competitive protein-binding analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197293"} {"pmid": "4197294", "title": "Polyacrylamide gel electrophoresis of human sera collected at different times after meals.", "content": "Polyacrylamide gel electrophoresis of human sera collected at different times after meals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197294"} {"pmid": "4197295", "title": "Evidence for a 5'-nucleotidase in human leukemic leukocytes.", "content": "Evidence for a 5'-nucleotidase in human leukemic leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197295"} {"pmid": "4197288", "title": "Detecting Marek's disease herpesvirus: evaluation of biological systems.", "content": "Detecting Marek's disease herpesvirus: evaluation of biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197288"} {"pmid": "4197296", "title": "Immunochemical study of relationships between erythrocyte glucose-6-phosphate dehydrogenase (G6PD, E.C. 1.1.1.49) of various mammalian species.", "content": "Immunochemical study of relationships between erythrocyte glucose-6-phosphate dehydrogenase (G6PD, E.C. 1.1.1.49) of various mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197296"} {"pmid": "4197289", "title": "Microimmunodiffusion test for hemorrhagic enteritis of turkeys.", "content": "Microimmunodiffusion test for hemorrhagic enteritis of turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197289"} {"pmid": "4197298", "title": "The biochemical properties of esterases in Cepaea (Mollusca: Helicidae).", "content": "The biochemical properties of esterases in Cepaea (Mollusca: Helicidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197298"} {"pmid": "4197297", "title": "Incorporation of 32 P during early amphibian embryogenesis.", "content": "Incorporation of 32 P during early amphibian embryogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197297"} {"pmid": "4197299", "title": "Experimental induction heating hypophysectomy.", "content": "Experimental induction heating hypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197299"} {"pmid": "4197300", "title": "Properties of glycogen synthetase in erythrocytes.", "content": "Properties of glycogen synthetase in erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197300"} {"pmid": "4197302", "title": "Enzymic changes in taste buds of monkey following transection of glossopharyngeal nerve.", "content": "Enzymic changes in taste buds of monkey following transection of glossopharyngeal nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197302"} {"pmid": "4197304", "title": "Protein A from Staphylococcus aureus. XIV. The effect of nitration of protein A with tetranitromethane and subsequent reduction.", "content": "Protein A from Staphylococcus aureus. XIV. The effect of nitration of protein A with tetranitromethane and subsequent reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197304"} {"pmid": "4197303", "title": "Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet.", "content": "Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197303"} {"pmid": "4197305", "title": "A new preparative method for isolation of human C3 with affinity chromatography.", "content": "A new preparative method for isolation of human C3 with affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197305"} {"pmid": "4197306", "title": "Immunochemical study of group A streptococcus peptidoglycan solubilized by 8M urea.", "content": "Immunochemical study of group A streptococcus peptidoglycan solubilized by 8M urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197306"} {"pmid": "4197307", "title": "Histochemical evidence for phosphorylase, branching enzyme and glycogen synthetase activities in rat brain.", "content": "Histochemical evidence for phosphorylase, branching enzyme and glycogen synthetase activities in rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197307"} {"pmid": "4197312", "title": "Death and dying. A critical review of the literature.", "content": "Death and dying. A critical review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197312"} {"pmid": "4197314", "title": "Analyses of proteinases in washing powders.", "content": "Analyses of proteinases in washing powders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197314"} {"pmid": "4197316", "title": "The retro-articular vertebral artery ring of the atlas and its significance.", "content": "The retro-articular vertebral artery ring of the atlas and its significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197316"} {"pmid": "4197318", "title": "Diverticulum or aneurysm of left ventricle.", "content": "Diverticulum or aneurysm of left ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197318"} {"pmid": "4197310", "title": "Evidence for possible precursors in the synthesis of growth hormone by rat and human fetal anterior pituitary in vitro.", "content": "Evidence for possible precursors in the synthesis of growth hormone by rat and human fetal anterior pituitary in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197310"} {"pmid": "4197311", "title": "Inherited variations in thyroxine transport.", "content": "Inherited variations in thyroxine transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197311"} {"pmid": "4197319", "title": "Basis of static and dynamic electrocardiographic variations in Wolff-Parkinson-White syndrome. Anatomic and electrophysiologic observations in right and left ventricular preexcitation.", "content": "Basis of static and dynamic electrocardiographic variations in Wolff-Parkinson-White syndrome. Anatomic and electrophysiologic observations in right and left ventricular preexcitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197319"} {"pmid": "4197320", "title": "The acylation of glycerol 3 -phosphate in different rat organs and in the liver of different species (including man).", "content": "The acylation of glycerol 3 -phosphate in different rat organs and in the liver of different species (including man).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197320"} {"pmid": "4197321", "title": "Dysplasia epiphysialis hemimelica with confirmation by knee arthrography.", "content": "Dysplasia epiphysialis hemimelica with confirmation by knee arthrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197321"} {"pmid": "4197309", "title": "Regulation of growth hormone and prolactin secretion in patients with acromegaly and-or excessive prolactin secretion.", "content": "Regulation of growth hormone and prolactin secretion in patients with acromegaly and-or excessive prolactin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197309"} {"pmid": "4197322", "title": "Visual discrimination performance in the monkey: the activity of single cells in infero-termporal cortex.", "content": "Visual discrimination performance in the monkey: the activity of single cells in infero-termporal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197322"} {"pmid": "4197323", "title": "Certain ventromedial hypothalamic afferents.", "content": "Certain ventromedial hypothalamic afferents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197323"} {"pmid": "4197313", "title": "Clinical grade, egional cerebral blood flow and angiographical spasm in the monkey after subarachnoid and subdural hemorrhage.", "content": "Clinical grade, egional cerebral blood flow and angiographical spasm in the monkey after subarachnoid and subdural hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197313"} {"pmid": "4197325", "title": "Gonorrhea: changing concepts in diagnosis and management.", "content": "Gonorrhea: changing concepts in diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197325"} {"pmid": "4197324", "title": "Septic shock (endotoxic shock).", "content": "Septic shock (endotoxic shock). The pathophysiology, clinical aspects, medical, and surgical management of endotoxin shock are reviewed. In the primate, the pathophysiology of endotoxin shock is contributed to by selective vasopasm, disseminated intravascular coagulation, and reduced myocardial response to sympathetic stimuli. Studies in the baboon measured various parameters of hemodynamics and coagulation, catecholamines, and some biochemical changes following the injection of a single bolus of endotoxin. Hemodynamic studies pointed to the kidney as a primary target organ. Coagulation changes included alterations in factor XII and XIII (and others) and plasminogen. Deposition of fibrin was also noted. Neurohormonal studies using tritiated norepinephrine showed a sharp rise in catecholamines 3 minutes after injection of endotoxin followed by a return to normal within 120 minutes, confirming the role of vasopasm in reducing renal perfusion early in shock. Prevention of septic shock is the best way to eradicate the extremely high reported mortality rates; infected abortion, chorioamnionitis, and pyelonephritis should all be warning signals. Methods of monitoring the patient in septic shock with special attention to blood pressure, central venous pressure, blood volume changes, and urinary output are discussed. Early surgical intervention and the proper use of vasomotor drugs and corticosteroids enhance patient survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197324"} {"pmid": "4197327", "title": "A proposed role for ascorbate in the transport of amino acids and ions in the cornea.", "content": "A proposed role for ascorbate in the transport of amino acids and ions in the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197327"} {"pmid": "4197328", "title": "The toad's (Bufo marinus) lens and urinary bladder as mural membranes: a comparison.", "content": "The toad's (Bufo marinus) lens and urinary bladder as mural membranes: a comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197328"} {"pmid": "4197330", "title": "6-Azauracil induced phenocopies of rudimentary wing mutants and their suppression by a suppressor mutant of rudimentary in Drosophila melanogaster.", "content": "6-Azauracil induced phenocopies of rudimentary wing mutants and their suppression by a suppressor mutant of rudimentary in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197330"} {"pmid": "4197331", "title": "Somatic resistance to X-ray treatment in Drosophila melanogaster populations with different irradiation backgrounds.", "content": "Somatic resistance to X-ray treatment in Drosophila melanogaster populations with different irradiation backgrounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197331"} {"pmid": "4197333", "title": "Complement: optimal reaction conditions for guinea pig C4.", "content": "Complement: optimal reaction conditions for guinea pig C4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197333"} {"pmid": "4197332", "title": "In vitro IgM antibody synthesis by human tonsil-derived lymphocytes.", "content": "In vitro IgM antibody synthesis by human tonsil-derived lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197332"} {"pmid": "4197334", "title": "Complement: a reversible temperature-dependent alteration in the reactivity of EAC1 with C4.", "content": "Complement: a reversible temperature-dependent alteration in the reactivity of EAC1 with C4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197334"} {"pmid": "4197335", "title": "Lysosomal enzyme release from human leukocytes: mediation by the alternate pathway of complement activation.", "content": "Lysosomal enzyme release from human leukocytes: mediation by the alternate pathway of complement activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197335"} {"pmid": "4197336", "title": "Antigen-T lymphocyte interactions: inhibition by cytochalasin B.", "content": "Antigen-T lymphocyte interactions: inhibition by cytochalasin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197336"} {"pmid": "4197308", "title": "Hyperlipidemia and diabetes mellitus: can electron microscopy help in the diagnosis.", "content": "Hyperlipidemia and diabetes mellitus: can electron microscopy help in the diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197308"} {"pmid": "4197337", "title": "Regulation of ribonucleic acid synthesis in Escherichia coli B-r: an analysis of a shift-up. II. Fraction of RNA polymerase engaged in the synthesis of stable RNA at different steady-state growth rates.", "content": "Regulation of ribonucleic acid synthesis in Escherichia coli B-r: an analysis of a shift-up. II. Fraction of RNA polymerase engaged in the synthesis of stable RNA at different steady-state growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197337"} {"pmid": "4197338", "title": "Occurrence of heat-dissociable ribosomal RNA in insects: the presence of three polynucleotide chains in 26 S RNA from cultured Aedes aegypti cells.", "content": "Occurrence of heat-dissociable ribosomal RNA in insects: the presence of three polynucleotide chains in 26 S RNA from cultured Aedes aegypti cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197338"} {"pmid": "4197339", "title": "Response to noise of auditory nerve fibers in the squirrel monkey.", "content": "Response to noise of auditory nerve fibers in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197339"} {"pmid": "4197340", "title": "Role of abducens neurons in vestibuloocular reflex.", "content": "Role of abducens neurons in vestibuloocular reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197340"} {"pmid": "4197341", "title": "Location of cells of origin of spinothalamic tract in lumbar enlargement of the monkey.", "content": "Location of cells of origin of spinothalamic tract in lumbar enlargement of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197341"} {"pmid": "4197342", "title": "The histopathology of vesical diverticula.", "content": "The histopathology of vesical diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197342"} {"pmid": "4197343", "title": "Neoplasm in vesical diverticula: report of 4 patients, including a 21-year-old.", "content": "Neoplasm in vesical diverticula: report of 4 patients, including a 21-year-old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197343"} {"pmid": "4197346", "title": "Isolation, purification and structure of Aleutian disease virus by immunological techniques.", "content": "Isolation, purification and structure of Aleutian disease virus by immunological techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197346"} {"pmid": "4197347", "title": "Does the rDNA in the Y chromosome of Drosophila melanogaster magnify?", "content": "Does the rDNA in the Y chromosome of Drosophila melanogaster magnify?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197347"} {"pmid": "4197348", "title": "Neural control of social behavior: prefrontal and anterior temporal cortex.", "content": "Neural control of social behavior: prefrontal and anterior temporal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197348"} {"pmid": "4197349", "title": "Functional dissociation between the inferior and arcuate segments of dorsolateral prefrontal cortex in the monkey.", "content": "Functional dissociation between the inferior and arcuate segments of dorsolateral prefrontal cortex in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197349"} {"pmid": "4197350", "title": "Cross-modal transfer between vision and touch of go, no-go discrimination learning in the monkey.", "content": "Cross-modal transfer between vision and touch of go, no-go discrimination learning in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197350"} {"pmid": "4197353", "title": "Chlorthalidone in the treatment of angina pectoris.", "content": "Chlorthalidone in the treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197353"} {"pmid": "4197357", "title": "Effect of trisodium nitrilotriacetate (Na 3 NTA) on the metabolism of selected metal ions.", "content": "Effect of trisodium nitrilotriacetate (Na 3 NTA) on the metabolism of selected metal ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197357"} {"pmid": "4197359", "title": "Toxicity of (4,4'-(isopropylidenedithio)bis(2,6-di-t-butylphenol)), probucol, in mice, rats, dogs and monkeys: demonstration of a species-specific phenomenon.", "content": "Toxicity of (4,4'-(isopropylidenedithio)bis(2,6-di-t-butylphenol)), probucol, in mice, rats, dogs and monkeys: demonstration of a species-specific phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197359"} {"pmid": "4197358", "title": "Intestinal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique.", "content": "Intestinal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197358"} {"pmid": "4197360", "title": "Sensitization to epinephrine-induced ventricular fibrillation produced by probucol in dogs.", "content": "Sensitization to epinephrine-induced ventricular fibrillation produced by probucol in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197360"} {"pmid": "4197365", "title": "Effect of aflatoxins on microorganisms.", "content": "Effect of aflatoxins on microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197365"} {"pmid": "4197368", "title": "Hemodynamic changes during complete heart block in the unanesthetized monkey.", "content": "Hemodynamic changes during complete heart block in the unanesthetized monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197368"} {"pmid": "4197369", "title": "Detection of medullary thyroid cancer by calcitonin assay in families.", "content": "Detection of medullary thyroid cancer by calcitonin assay in families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197369"} {"pmid": "4197371", "title": "Asthma caused by nickel sensitivity.", "content": "Asthma caused by nickel sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197371"} {"pmid": "4197370", "title": "Rapid correction of hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone. An alternative treatment to hypertonic saline.", "content": "Rapid correction of hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone. An alternative treatment to hypertonic saline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197370"} {"pmid": "4197373", "title": "National health plans: some economic and financial aspects.", "content": "National health plans: some economic and financial aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197373"} {"pmid": "4197372", "title": "The early phase of acute myocardial infarction: pharmacologic aspects of therapy.", "content": "The early phase of acute myocardial infarction: pharmacologic aspects of therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197372"} {"pmid": "4197374", "title": "Cromolyn prophylaxis for chronic asthma.", "content": "Cromolyn prophylaxis for chronic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197374"} {"pmid": "4197375", "title": "Alcoholism and ketoacidosis.", "content": "Alcoholism and ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197375"} {"pmid": "4197377", "title": "Effects of bacterial products on a Paramecium esterase.", "content": "Effects of bacterial products on a Paramecium esterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197377"} {"pmid": "4197376", "title": "Electron microscopic studies on transplantable melanotic and amelanotic melanomas in hamsters.", "content": "Electron microscopic studies on transplantable melanotic and amelanotic melanomas in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197376"} {"pmid": "4197378", "title": "Studies of a homologous gene-enzyme system, esterase C, in Drosophila melanogaster and Drosophila simulans.", "content": "Studies of a homologous gene-enzyme system, esterase C, in Drosophila melanogaster and Drosophila simulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197378"} {"pmid": "4197380", "title": "The relationship of substrate, growth rate, and maintenance coefficient to single cell protein production.", "content": "The relationship of substrate, growth rate, and maintenance coefficient to single cell protein production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197380"} {"pmid": "4197379", "title": "Is hemoglobin A 2 important?", "content": "Is hemoglobin A 2 important?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197379"} {"pmid": "4197382", "title": "A method for the measurement of platelet adhesiveness by use of dialysis membranes in a test-cell.", "content": "A method for the measurement of platelet adhesiveness by use of dialysis membranes in a test-cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197382"} {"pmid": "4197381", "title": "Polysomes of cultured normal and leukaemic lymphocytes: response to phytohaemagglutinin.", "content": "Polysomes of cultured normal and leukaemic lymphocytes: response to phytohaemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197381"} {"pmid": "4197385", "title": "Body potassium and fat-free mass.", "content": "Body potassium and fat-free mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197385"} {"pmid": "4197384", "title": "The effect of anticonvulsant therapy upon the absorption of folates.", "content": "The effect of anticonvulsant therapy upon the absorption of folates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197384"} {"pmid": "4197386", "title": "Effects of long-term feeding of polychlorinated biphenyls (PCB, Clophen A 60) on the length of the oestrous cycle and on the frequency of implanted ova in the mouse.", "content": "Effects of long-term feeding of polychlorinated biphenyls (PCB, Clophen A 60) on the length of the oestrous cycle and on the frequency of implanted ova in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197386"} {"pmid": "4197387", "title": "Multiple myeloma proteins: evaluation of laboratory methods as aids for diagnosis.", "content": "Multiple myeloma proteins: evaluation of laboratory methods as aids for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197387"} {"pmid": "4197388", "title": "Transmissible mink encephalopathy: studies on the peripheral lymphocyte.", "content": "Transmissible mink encephalopathy: studies on the peripheral lymphocyte. Circulating lymphocytes from mink with transmissible mink encephalopathy were studied for the presence of virus particles and for infectivity. Electron microscope examination of phytohemagglutinin-stimulated lymphocyte cultures revealed no evidence of virus-like particles. Circulating lymphocytes were also found to be noninfectious when the transmissible agent could be demonstrated in intact lymphoid organs in infected mink. A lymphopenia was detected in affected mink during the late clinical stage of disease, but this was most likely a secondary effect due to a terminal stress factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197388"} {"pmid": "4197389", "title": "Studies on the virulence of Neisseria gonorrhoeae. I. Relation of colonial morphology and resistance to phagocytosis by polymorphonuclear leukocytes.", "content": "Studies on the virulence of Neisseria gonorrhoeae. I. Relation of colonial morphology and resistance to phagocytosis by polymorphonuclear leukocytes. Colonial varieties of Neisseria gonorrhoeae that are associated with virulence, types 1 and 2, were more resistant to phagocytosis by rabbit exudative polymorphonuclear leukocytes than colonial types of lesser virulence, types 3 and 4. Type 1 bacteria were resistant and type 4 gonococci were susceptible to phagocytosis by human polymorphonuclear leukocytes. Recent local type 1 isolates were similar in resistance to type 1 organisms of a standard laboratory strain (F62). Living and Formalin-treated, heat-killed, type 1 gonococci were equally resistant to phagocytosis. The antiphagocytic property of virulent colonial types was independent of leukotoxic action. Phagocytosis of both type 1 and type 4 gonococci by rabbit and human leukocytes was bactericidal. Rabbit leukocytes were superior to human leukocytes in killing gonococci. The results suggest that N. gonorrhoeae has virulence properties similar to those of extracellular bacterial pathogens, i.e., virulence is associated with antiphagocytic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197389"} {"pmid": "4197390", "title": "Mumps class-specific immunoglobulins in radioimmunoassay and conventional serology.", "content": "Mumps class-specific immunoglobulins in radioimmunoassay and conventional serology. In assessing the host cell range of bovine parvoviruses, these viruses were found to replicate optimally in actively dividing bovine fetal lung and spleen cells. Other primary bovine fetal cells supported growth to a lesser extent, but bovine line cells and line cells of other animal species tested did not. Minimal infectivity remained after passage of bovine parvovirus in cells from chicken embryos and guinea pig fetuses. During bovine parvovirus replication in bovine fetal lung and spleen cells, production kinetics of infectious virus and hemagglutinins were determined. An eclipse period of 16 h occurred, and viral release from cells was not detected until 30 h after inoculation of bovine fetal lung cells and 36 h after inoculation of bovine fetal spleen cells. Cell-associated virus titers were always higher than extracellular virus titers. Hemagglutinins were detected in parallel to infectious virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197390"} {"pmid": "4197391", "title": "Interaction of virulent and avirulent Listeria monocytogenes with cultured mouse peritoneal macrophages.", "content": "Interaction of virulent and avirulent Listeria monocytogenes with cultured mouse peritoneal macrophages. The interaction between smooth and rough Listeria monocytogenes and mouse peritoneal macrophages in culture was investigated. Initially, antibiotics were deleted from the culture medium, and no attempt other than the removal of unphagocytized bacteria by extensive washings was made to control extracellular growth. Under these conditions the monolayers were rapidly destroyed within an 8-h period, and this was associated with increases in the intracellular population of both strains. Extracellular viability counts revealed that washings failed to reduce the bacteria in the medium to less than 10% of the original inoculum. Continuous phagocytosis of Listeria which grew logarithmically in the maintenance media appears to account for the observed changes in the number of intracellular bacteria. The data also indicate that it is primarily the free bacteria in the culture medium which are responsible for the cytotoxic effects. In other experiments streptomycin-penicillin solutions were added to the maintenance media after an initial period of phagocytosis. In the presence of antibiotics, the total number of macrophages per field remained relatively constant, and no morphological alterations in the leukocyte cultures were observable. Extensive intracellular multiplication of either strain was not evident in fixed and stained cover slips. Viable intracellular counts reveal that after 24 h there is almost total killing of the rough variant, whereas the smooth strain tended towards complete survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197391"} {"pmid": "4197392", "title": "Effects of antithymocyte and antimacrophage sera on the survival of mice infected with Listeria monocytogenes.", "content": "Effects of antithymocyte and antimacrophage sera on the survival of mice infected with Listeria monocytogenes. Antisera prepared in rabbits against purified mouse thymocytes (antithymocyte serum; ATS) and peritoneal macrophages (antimacrophage serum; AMS) were injected intraperitoneally into Balb/c mice infected with the bacterium Listeria monocytogenes. When administered near the initiation of infection, the ATS significantly decreased the survival time of the animals and increased the mortality rate. When ATS was administered 6 days after a sublethal dose of L. monocytogenes had been inoculated, an overt disease did not evolve. ATS that significantly potentiated primary listeriosis also had high cytotoxicity titers for thymocytes and lymphoid cells from the peritoneal cavity. Although cytotoxic activity against peritoneal macrophages could be demonstrated in lower dilutions of the ATS, this activity did not appear to correlate with the effects of the sera on listeriosis. The injection of AMS did not enhance the infectious process. In some trials more deaths occurred among mice receiving normal rabbit serum than those receiving AMS. All of the AMS had cytotoxic titers against peritoneal macrophages, and the sera were usually inactive against thymocytes and peritoneal lymphoid cells. Listeria was isolated from fatally infected mice with nearly equal success in all of the serum-treated groups, and the serum treatments did not appear to alter the pattern of gross lesions. The afferent limb of the immune response was markedly affected by the presence of antibodies to lymphocytes. However, antibodies reacting with macrophages did not demonstrably enhance the Listeria process, which depends upon cellular immunity as the principal means of acquired host defense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197392"} {"pmid": "4197393", "title": "Nonhemolytic group B streptococci of human, bovine, and ichthyic origin.", "content": "Nonhemolytic group B streptococci of human, bovine, and ichthyic origin. The biochemical and serological characteristics of nonhemolytic group B streptococci of human, bovine, and ichthyic origin were described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197393"} {"pmid": "4197394", "title": "Salivary, nasal wash, and sputum IgA concentrations in atopic and nonatopic individuals.", "content": "Salivary, nasal wash, and sputum IgA concentrations in atopic and nonatopic individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197394"} {"pmid": "4197395", "title": "Stimulation of DNA synthesis and 2-deoxy-D-glucose transport in chick embryo cultures by excessive metal concentrations and by a carcinogenic hydrocarbon.", "content": "Stimulation of DNA synthesis and 2-deoxy-D-glucose transport in chick embryo cultures by excessive metal concentrations and by a carcinogenic hydrocarbon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197395"} {"pmid": "4197396", "title": "Ossifying fibroma of mandible with a case report.", "content": "Ossifying fibroma of mandible with a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197396"} {"pmid": "4197403", "title": "Kidney transplantation in Fabry's disease.", "content": "Kidney transplantation in Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197403"} {"pmid": "4197402", "title": "Committee on maternal welfare.", "content": "Committee on maternal welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197402"} {"pmid": "4197405", "title": "Cerebral cortical control of movement.", "content": "Cerebral cortical control of movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197405"} {"pmid": "4197406", "title": "Cardiovascular observations in the Macaca nemestrina monkey in Biosatellite 3.", "content": "Cardiovascular observations in the Macaca nemestrina monkey in Biosatellite 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197406"} {"pmid": "4197407", "title": "Circadian rhythms and sleep-wake activity in the Biosatellite monkey.", "content": "Circadian rhythms and sleep-wake activity in the Biosatellite monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197407"} {"pmid": "4197409", "title": "Electrolyte and metabolic problems of weightlessness.", "content": "Electrolyte and metabolic problems of weightlessness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197409"} {"pmid": "4197408", "title": "Wake and sleep cycles in the Biosatellite 3 primate in earth orbital flight.", "content": "Wake and sleep cycles in the Biosatellite 3 primate in earth orbital flight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197408"} {"pmid": "4197410", "title": "The prospect of life on Jupiter.", "content": "The prospect of life on Jupiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197410"} {"pmid": "4197413", "title": "Isolation and characterization of a virus infecting a blue-green alga of the genus Synechococcus.", "content": "Isolation and characterization of a virus infecting a blue-green alga of the genus Synechococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197413"} {"pmid": "4197414", "title": "Aspects of the developmental morphology of California encephalitis virus in cultured vertebrae and arthropod cells and in mouse brain.", "content": "Aspects of the developmental morphology of California encephalitis virus in cultured vertebrae and arthropod cells and in mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197414"} {"pmid": "4197415", "title": "Accommodation of the eye during sleep and anesthesia.", "content": "Accommodation of the eye during sleep and anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197415"} {"pmid": "4197416", "title": "The oscillatory waves of the primate electroretinogram.", "content": "The oscillatory waves of the primate electroretinogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197416"} {"pmid": "4197417", "title": "Retinal receptive fields: correlations between psychophysics and electrophysiology.", "content": "Retinal receptive fields: correlations between psychophysics and electrophysiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197417"} {"pmid": "4197418", "title": "Servo-controlled moving stimulus generator for single unit studies in vision.", "content": "Servo-controlled moving stimulus generator for single unit studies in vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197418"} {"pmid": "4197420", "title": "Field trial of the efficacy of a previously proposed regimen using minocycline and rifampin sequentially for the elimination of meningococci from healthy carriers.", "content": "Field trial of the efficacy of a previously proposed regimen using minocycline and rifampin sequentially for the elimination of meningococci from healthy carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197420"} {"pmid": "4197423", "title": "Induced hypothermia: its place in modern hospital practice.", "content": "Induced hypothermia: its place in modern hospital practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197423"} {"pmid": "4197421", "title": "Massive hemorrhage associated with circulating antibodies to factor V.", "content": "Massive hemorrhage associated with circulating antibodies to factor V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197421"} {"pmid": "4197422", "title": "Experimental calcification of the myocardium. Ultrastructural and histochemical investigations.", "content": "Experimental calcification of the myocardium. Ultrastructural and histochemical investigations. Focal areas of calcification are frequent in rat myocardium 30 and 60 days after administration of dihydrotachysterol. These areas are PAS-positive, stain deeply with alcian blue and show high affinity for colloidal iron. Calcification is almost completely confined to intracellular structures. Small clusters of needle-shaped crystals are first found in apparently undamaged mitochondria in undamaged myocardial cells. When all the mitochondria are calcified, the cell degenerates, and inorganic crystals are laid down in relationship with its myofilaments. In other myocardial cells, clusters of amorphous or finely granular inorganic substance are found in both mitochondria and myofibrils. Both structures show signs of advanced degeneration. Inorganic substance has only occasionally been found within the structures of the sarcoplasmic reticulum. These structures do not seem to be involved in myocardial calcification under the present experimental conditions. Calcification of myocardial cells gives rise to a cellular reaction. Many macrophagic cells surround the calcified areas, which are rapidly reabsorbed. The present results show that myocardial mitochondria are actively engaged in controlling the intracellular concentration and movement of calcium ions. Their role in the myocardial contraction-relaxation cycle and the possible mechanism of myocardial calcification are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197422"} {"pmid": "4197419", "title": "Progress in oral therapy of diabetes mellitus with sulphonylureas of the second generation.", "content": "Progress in oral therapy of diabetes mellitus with sulphonylureas of the second generation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197419"} {"pmid": "4197427", "title": "Representation of information about skin temperature in the discharge of single cortical neurons.", "content": "Representation of information about skin temperature in the discharge of single cortical neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197427"} {"pmid": "4197426", "title": "Formylation of folate as step in physiological folate absorption.", "content": "Formylation of folate as step in physiological folate absorption. Oral administration of folate analogues to rats is followed by a rise in plasma folate detectable only by micro-biological assay with Lactobacillus casei, suggesting methylation of folate during absorption. When using the everted rat gut technique with folate (PteGlu), dihydrofolate (H(2)PteGlu), or tetrahydrofolate (H(4)PteGlu) on the mucosal surface formyl folate (10-CHO-PteGlu, 10-CHO-H(4)PteGlu, 5-CHO-H(4)PteGlu) and methylfolate (5-CH(3)-H(4)PteGlu) are recovered from the serosal fluid. This indicates that absorption of PteGlu is followed by formylation and that the formyl group is further reduced to methyl, 5-CH(3)-H(4)PteGlu passing on to portal blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197426"} {"pmid": "4197425", "title": "Euglycaemic diabetic ketoacidosis.", "content": "Euglycaemic diabetic ketoacidosis. Of a series of 211 episodes of diabetic metabolic decompensation 37 had severe euglycaemic ketoacidosis (a blood sugar level of less than 300 mg/100 ml and a plasma bicarbonate of 10 mEq/1. or less). All were young insulin-dependent diabetics, only one being previously undiagnosed. Vomiting was a common factor, and in all carbohydrate reduction occurred with continued or increased daily insulin dose. Treatment comprised fluid and electrolyte replacement and large doses of insulin covered by adequate carbohydrate, many receiving 10% dextrose. Alkali was either withheld or given sparingly and the therapy was monitored by serial estimations of plasma bicarbonate. All the patients survived.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197425"} {"pmid": "4197428", "title": ", Mishkin M:Comparison of superior temporal and inferior prefrontal lesions on auditory and non-auditory tasks in rhesus monkeys.", "content": ", Mishkin M:Comparison of superior temporal and inferior prefrontal lesions on auditory and non-auditory tasks in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197428"} {"pmid": "4197429", "title": "Cutaneous receptive fields of primate cold fibers.", "content": "Cutaneous receptive fields of primate cold fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197429"} {"pmid": "4197430", "title": "Studies on isolated keratin fractions from mammalian epidermis. II. Immunological and immuno-electrophoretic comparison of the fractions.", "content": "Studies on isolated keratin fractions from mammalian epidermis. II. Immunological and immuno-electrophoretic comparison of the fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197430"} {"pmid": "4197433", "title": "Interactions of sensory and nonspecific thalamic inputs to cortical polysensory units in the squirrel monkey.", "content": "Interactions of sensory and nonspecific thalamic inputs to cortical polysensory units in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197433"} {"pmid": "4197432", "title": "Position sense after combined spinal tractotomies and cerebellectomies in macaques.", "content": "Position sense after combined spinal tractotomies and cerebellectomies in macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197432"} {"pmid": "4197435", "title": "B-lymphocyte mediated cytolysis: a complement independent phenomenon.", "content": "B-lymphocyte mediated cytolysis: a complement independent phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197435"} {"pmid": "4197436", "title": "Incidence of Australia antigen in voluntary and professional blood donors and also in cases of viral hepatitis.", "content": "Incidence of Australia antigen in voluntary and professional blood donors and also in cases of viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197436"} {"pmid": "4197434", "title": "Specific hapten binding activity in normal sera.", "content": "Specific hapten binding activity in normal sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197434"} {"pmid": "4197437", "title": "Cost accounting of health centre expenditures.", "content": "Cost accounting of health centre expenditures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197437"} {"pmid": "4197438", "title": "Airway problems in the intensive care unit.", "content": "Airway problems in the intensive care unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197438"} {"pmid": "4197440", "title": "Micromethod for immunochemical quantitation of dextran and studies on role of antigen size in single radial immunodiffusion.", "content": "Micromethod for immunochemical quantitation of dextran and studies on role of antigen size in single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197440"} {"pmid": "4197439", "title": "Lysis of antibody-treated human erythrocytes by human leukocytes and macrophages in tissue culture.", "content": "Lysis of antibody-treated human erythrocytes by human leukocytes and macrophages in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197439"} {"pmid": "4197441", "title": "Defined immunofluorescence studies of cytoplasmic antibodies.", "content": "Defined immunofluorescence studies of cytoplasmic antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197441"} {"pmid": "4197442", "title": "Ambient light, white noise, and monkey vocalization as sources of interference in visual short-term memory of monkeys.", "content": "Ambient light, white noise, and monkey vocalization as sources of interference in visual short-term memory of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197442"} {"pmid": "4197444", "title": "Comparative study of myocardial lesions in hemorrhagic shock.", "content": "Comparative study of myocardial lesions in hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197444"} {"pmid": "4197443", "title": "Spectrofluorometric determination of substituted dihydroisoquinolines and tertiary tetrahydroisoquinolines as their isoquinolinium derivatives.", "content": "Spectrofluorometric determination of substituted dihydroisoquinolines and tertiary tetrahydroisoquinolines as their isoquinolinium derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197443"} {"pmid": "4197445", "title": "Effects of pressure gradient changes on the morphology of arachnoid villi and granulations of the monkey.", "content": "Effects of pressure gradient changes on the morphology of arachnoid villi and granulations of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197445"} {"pmid": "4197450", "title": "Capacitor electrode stimulates nerve or muscle without oxidation-reduction reactions.", "content": "Capacitor electrode stimulates nerve or muscle without oxidation-reduction reactions. Porous tantalum disks, available as \"slugs\" from the capacitor industry, have large available surface area and a thin insulating coating of tantalum pentoxide. When implanted, they fill with extracellular fluid and operate as capacitor-stimulating electrodes having high capacitance per unit volume. Capable of stimulating excitable tissute without generating electrochemical by-products, these electrodes should provide a safer interface between neural prosthetic devices and human tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197450"} {"pmid": "4197452", "title": "Renal blood flow during endotoxin shock in the subhuman primate.", "content": "Renal blood flow during endotoxin shock in the subhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197452"} {"pmid": "4197453", "title": "Elemental diet in the treatment of fistulas of the alimentary tract.", "content": "Elemental diet in the treatment of fistulas of the alimentary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197453"} {"pmid": "4197454", "title": "The ocular manifestations of congenital rubella.", "content": "The ocular manifestations of congenital rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197454"} {"pmid": "4197460", "title": "Safe use of pesticides.", "content": "Safe use of pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197460"} {"pmid": "4197463", "title": "Status of monosodium glutamate revisited.", "content": "Status of monosodium glutamate revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197463"} {"pmid": "4197462", "title": "Status of monosodium glutamate revisited.", "content": "Status of monosodium glutamate revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197462"} {"pmid": "4197464", "title": "Folate content of diets in pregnancy: comparison of diets collected at home and diets prepared from dietary records.", "content": "Folate content of diets in pregnancy: comparison of diets collected at home and diets prepared from dietary records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197464"} {"pmid": "4197465", "title": "The neglect of nutrition and its perils.", "content": "The neglect of nutrition and its perils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197465"} {"pmid": "4197466", "title": "Nutrition: its relationship to children's physical, mental, and emotional development.", "content": "Nutrition: its relationship to children's physical, mental, and emotional development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197466"} {"pmid": "4197467", "title": "Graded contractions in muscle strips and single cells from Bufo marinus stomach.", "content": "Graded contractions in muscle strips and single cells from Bufo marinus stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197467"} {"pmid": "4197468", "title": "Variation in endotoxin-induced kinin production and effect between the rabbit and rhesus monkey.", "content": "Variation in endotoxin-induced kinin production and effect between the rabbit and rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197468"} {"pmid": "4197469", "title": "Toxicology of radionuclides.", "content": "Toxicology of radionuclides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197469"} {"pmid": "4197471", "title": "Heterotopic ossification in abdominal operation scars.", "content": "Heterotopic ossification in abdominal operation scars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197471"} {"pmid": "4197470", "title": "Neuropharmacology of the affective disorders.", "content": "Neuropharmacology of the affective disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197470"} {"pmid": "4197472", "title": "Spondylo-metaphyseal dysplasia.", "content": "Spondylo-metaphyseal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197472"} {"pmid": "4197473", "title": "Dyggve disease.", "content": "Dyggve disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197473"} {"pmid": "4197476", "title": "Scleromalacia perforans associated with Crohn's disease. Treated with sodium versenate (EDTA).", "content": "Scleromalacia perforans associated with Crohn's disease. Treated with sodium versenate (EDTA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197476"} {"pmid": "4197477", "title": "Increased dosage of disodium cromoglycate.", "content": "Increased dosage of disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197477"} {"pmid": "4197475", "title": "The effect of D-L-erythro- - -dihydroxybutyraldehyde (DIBA) on the spores of Bacillus cereus: germination, stimulation and outgrowth inhibition.", "content": "The effect of D-L-erythro- - -dihydroxybutyraldehyde (DIBA) on the spores of Bacillus cereus: germination, stimulation and outgrowth inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197475"} {"pmid": "4197503", "title": "Efficacy of glibenclamide in maturity-onset diabetics as maintenance therapy.", "content": "Efficacy of glibenclamide in maturity-onset diabetics as maintenance therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197503"} {"pmid": "4197504", "title": "Effect of oxytocin and epinephrine on the adenylate cyclase activity of myometrium from pregnant Rhesus monkeys.", "content": "Effect of oxytocin and epinephrine on the adenylate cyclase activity of myometrium from pregnant Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197504"} {"pmid": "4197505", "title": "Fixed-interval schedule of cocaine reinforcement: effect of dose and infusion duration.", "content": "Fixed-interval schedule of cocaine reinforcement: effect of dose and infusion duration. Rhesus monkeys were trained on a fixed-interval 9-min limited-hold 3-min schedule of intravenous cocaine reinforcement. A 15-min timeout followed each reinforcement or limited-hold expiration. An identical schedule of food reinforcement was interspersed in the session to assess rate-modifying effects of the drug infusions not specific to drug reinforcement. In one experiment, response rate for cocaine reinforcement was shown to be a positive function of reinforcement magnitude for a dose range from 0 to 800 ug/kg/inj. At these doses, there was little effect on food reinforced responding except at the highest dose, where responding decreased. Results of the second experiment indicated that increasing the duration of the cocaine infusion produced a change in response rate similar to decreasing unit dose. The response rate change for a given increase in infustion duration was less at a unit dose of 400 ug/kg than at 200 ug/kg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197505"} {"pmid": "4197506", "title": "Long-term prereward suppression in monkeys unaccompanied by cardiovascular conditioning.", "content": "Long-term prereward suppression in monkeys unaccompanied by cardiovascular conditioning. In Experiment I, a 3-min tone that preceded a free pellet of food suppressed variable-interval performances maintained by the same type of pellets, but failed to elicit conditioned changes in the heart rates and blood pressures of two rhesus monkeys. Initially severe, the prereward suppression became temporally discriminated to progressively later portions of the tone, and was maintained at an attenuated level for over four months. The suppression was apparently not caused by interfering autonomic respondents, nor was it superstitiously conditioned, since 21 of the initial 25 tone-food pairings took place outside of baseline sessions. In Experiment II, a 1-min light, paired with four free pellets of food, suppressed the variable-interval responding of a second pair of similarly trained monkeys. An interresponse-time analysis showed that in one subject, mild prereward suppression of responding developed through two stages. On early trials, response rate slowed by 10% throughout the prefood interval. On later trials, the animal suppressed by pausing for a like portion of the interval, most often near the end, but otherwise responded normally during the prefood signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197506"} {"pmid": "4197507", "title": "The chronic toxicity of retrorsine, a pyrrolizidine alkaloid, in vervet monkeys.", "content": "The chronic toxicity of retrorsine, a pyrrolizidine alkaloid, in vervet monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197507"} {"pmid": "4197516", "title": "Use of thyrotrophin releasing hormone test in pituitary disease.", "content": "Use of thyrotrophin releasing hormone test in pituitary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197516"} {"pmid": "4197517", "title": "Effect of pyrithioxine (Encephabol) on growth and exploratory behaviour of rats malnourished in early life.", "content": "Effect of pyrithioxine (Encephabol) on growth and exploratory behaviour of rats malnourished in early life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197517"} {"pmid": "4197518", "title": "The nature of performance deficity under secobarbital and chlorpromazine in the monkey. A behavioral and EEG study.", "content": "The nature of performance deficity under secobarbital and chlorpromazine in the monkey. A behavioral and EEG study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197518"} {"pmid": "4197520", "title": "Studies on gold therapy with 198 gold sodium thiomalate.", "content": "Studies on gold therapy with 198 gold sodium thiomalate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197520"} {"pmid": "4197524", "title": "Prevention by cycloheximide of neutral red-induced formation of autophagic vacuoles and krinom granules in mouse pancreatic acinar cells.", "content": "Prevention by cycloheximide of neutral red-induced formation of autophagic vacuoles and krinom granules in mouse pancreatic acinar cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197524"} {"pmid": "4197525", "title": "Morphological studies of cultured swine aorta media explants.", "content": "Morphological studies of cultured swine aorta media explants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197525"} {"pmid": "4197526", "title": "Effects of anti-thymocyte serum on the phagocytic acivity of hepatic and splenic macrophages.", "content": "Effects of anti-thymocyte serum on the phagocytic acivity of hepatic and splenic macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197526"} {"pmid": "4197528", "title": "Intranuclear mitochondriae in Hodgkin's disease.", "content": "Intranuclear mitochondriae in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197528"} {"pmid": "4197529", "title": "The centrineurogenic etiology of the acute respiratory distress syndromes. Universal, species--independent phenomenon.", "content": "The centrineurogenic etiology of the acute respiratory distress syndromes. Universal, species--independent phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197529"} {"pmid": "4197532", "title": "Economic pressures--and quality nursing.", "content": "Economic pressures--and quality nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197532"} {"pmid": "4197530", "title": "Tricuspid valvulectomy without prosthetic replacement.", "content": "Tricuspid valvulectomy without prosthetic replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197530"} {"pmid": "4197533", "title": "Antibacterial effect of an interferon-inducing polycarboxylate. Mechanism of action.", "content": "Antibacterial effect of an interferon-inducing polycarboxylate. Mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197533"} {"pmid": "4197534", "title": "Detection of homocytotropic human antibodies by passive sensitization \"in vitro\" of monkey lung tissue. I. Optimum conditions fo use of lung tissue.", "content": "Detection of homocytotropic human antibodies by passive sensitization \"in vitro\" of monkey lung tissue. I. Optimum conditions fo use of lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197534"} {"pmid": "4197535", "title": "Fixation of albumin to the hinge region of a macroglobulin.", "content": "Fixation of albumin to the hinge region of a macroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197535"} {"pmid": "4197536", "title": "Miliary tuberculosis in British Columbia.", "content": "Miliary tuberculosis in British Columbia. The case records were studied of all 48 patients with miliary tuberculosis registered by the British Columbia Division of Tuberculosis Control between 1967 and 1971. Two groups of patients were found, one group of 30 in whom the diagnosis was made during life and antituberculous therapy instituted, and a second group of 18 patients in whom the diagnosis was made only at autopsy and who had received no antituberculous therapy. In the latter group there was a particularly high incidence of concomitant disease; additionally, tuberculin testing, bacteriological search for acid-fast bacilli and chest radiography were frequently neglected. This group consisted mainly of elderly male Caucasians. The disease was characteristically insidious in onset, frequently with non-specific symptoms and physical findings. Fever was a common presenting symptom. Several patients presented with a fulminant illness which, although diagnosed, was not affected by antituberculous therapy and was rapidly fatal. North American Indians showed a high incidence of disease but a low mortality rate, probably owing to their younger age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197536"} {"pmid": "4197538", "title": "Analysis of lactic dehydrogenase in the lethal toad hybrid Bufo americanus female times Bufo marinus male.", "content": "Analysis of lactic dehydrogenase in the lethal toad hybrid Bufo americanus female times Bufo marinus male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197538"} {"pmid": "4197537", "title": "The prophylaxis of nonindustrial urothelial tumours.", "content": "The prophylaxis of nonindustrial urothelial tumours. Present knowledge concerning carcinogenesis and the natural history of urothelial tumours precludes firm conclusions relative to nonindustrial prophylaxis. However, a number of measures are consistent with current data and may be instituted for those patients with a demonstrated propensity to urothelial tumours. Their acceptability is based on the lack of associated toxicity for the patient. These measures include the elimination of significant infection, cigarettes, artificial sweeteners, analgesic abuse and coffee, the administration of vitamins C and B(6), and in selected cases, the use of thiotepa. It is emphasized that the merit of these steps in altering the natural history of urothelial tumours is uncertain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197537"} {"pmid": "4197540", "title": "Avian hepatic esterases, pesticides and diet.", "content": "Avian hepatic esterases, pesticides and diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197540"} {"pmid": "4197539", "title": "Pyruvate kinase isozymes: a comparative study in tissues of various mammalian species.", "content": "Pyruvate kinase isozymes: a comparative study in tissues of various mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197539"} {"pmid": "4197541", "title": "The effects of washing, EDTA, magnesium and calcium on oxidative phosphorylation and respiratory rates of mitochondria from heat- and cold-acclimated rats.", "content": "The effects of washing, EDTA, magnesium and calcium on oxidative phosphorylation and respiratory rates of mitochondria from heat- and cold-acclimated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197541"} {"pmid": "4197542", "title": "Australia antigen and primary biliary cirrhosis.", "content": "Australia antigen and primary biliary cirrhosis. Sera from 64 patients with primary biliary cirrhosis have been examined for Australia antigen (Au). On immunodiffusion and immunoelectrophoresis all sera were negative. Using a radioimmunoprecipitation technique 15.6% of sera contained antigen compared with an incidence of 3.1% in matched controls, a significant difference (p = 0.015). Anti-Au was found in 9.4% of patients and in 7.8% of controls. In lymphocyte transformation studies lymphocytes from one of 24 patients with primary biliary cirrhosis transformed on stimulation with an Au-rich serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197542"} {"pmid": "4197544", "title": "Electrofocusing of hepatitis B antigen and possible applications to radioimmunoassay techniques.", "content": "Electrofocusing of hepatitis B antigen and possible applications to radioimmunoassay techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197544"} {"pmid": "4197531", "title": "Phosphorylase activity in the arterial wall.", "content": "Phosphorylase activity in the arterial wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197531"} {"pmid": "4197543", "title": "Association of white cell and red cell antibodies in human sera.", "content": "Association of white cell and red cell antibodies in human sera. Five hundred and eighteen human sera containing known red cell antibodies were tested for lymphocytotoxic antibodies and 81 sera were found to contain them. Thirty-nine antibodies were fully characterized. The frequencies of anti-I, K, V(w), and Wr(a) were significantly greater in those of the 518 sera which also contained white cell antibodies.Four hundred and ninety-four of the 518 sera containing red cell antibodies contained anti-Rh and anti-Kell. The frequency of white cell antibodies in this group was 15% compared with a frequency of 12% in a series of 923 antenatal samples not containing anti-Rh or anti-Kell. The frequencies of different anti-HL-A specificities were compared in the two groups with or without anti-Rh and anti-Kell antibodies. Anti-HL-A 1, 7, and 8 occurred more frequently in the absence of these red cell antibodies and anti-HL-A 12 occurred more frequently in their presence. No correlation was found between particular red cell and white cell antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197543"} {"pmid": "4197545", "title": "Carcinogenic activity of benzofuran and dibenzofuran analogs of p-dimethylaminoazobenzene.", "content": "Carcinogenic activity of benzofuran and dibenzofuran analogs of p-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197545"} {"pmid": "4197546", "title": "Epidemilogy of Pseudomonas in a burn intensive care unit.", "content": "Epidemilogy of Pseudomonas in a burn intensive care unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197546"} {"pmid": "4197569", "title": "Eukaryotes-prokaryotes divergence estimated by 5S ribosomal RNA sequences.", "content": "Eukaryotes-prokaryotes divergence estimated by 5S ribosomal RNA sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197569"} {"pmid": "4197568", "title": "Enhancement of ampicillin efficacy by peroral levodopa in rat pyelonephritis.", "content": "Enhancement of ampicillin efficacy by peroral levodopa in rat pyelonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197568"} {"pmid": "4197570", "title": "On the mode of action of BCG.", "content": "On the mode of action of BCG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197570"} {"pmid": "4197571", "title": "Prospects for research on schizophrenia. 3. Neurophysiology. Isolation-rearing in primates.", "content": "Prospects for research on schizophrenia. 3. Neurophysiology. Isolation-rearing in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197571"} {"pmid": "4197572", "title": "Prospects for research on schizophrenia. 3. Neurophysiology. Primate behavioral pathology under field and laboratory conditions.", "content": "Prospects for research on schizophrenia. 3. Neurophysiology. Primate behavioral pathology under field and laboratory conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197572"} {"pmid": "4197573", "title": "Prospects for research on schizophrenia. VII. Prospects for research in schizophrenia. An overview.", "content": "Prospects for research on schizophrenia. VII. Prospects for research in schizophrenia. An overview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197573"} {"pmid": "4197574", "title": "Combined bactericidal activity of sodium sulphacetamide and cetrimonium bromide.", "content": "Combined bactericidal activity of sodium sulphacetamide and cetrimonium bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197574"} {"pmid": "4197576", "title": "Unreduced dislocations.", "content": "Unreduced dislocations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197576"} {"pmid": "4197577", "title": "Personal monitoring device for gaseous contaminants.", "content": "Personal monitoring device for gaseous contaminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197577"} {"pmid": "4197578", "title": "Stability of nitroglycerin in aqueous solution.", "content": "Stability of nitroglycerin in aqueous solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197578"} {"pmid": "4197580", "title": "Neurofibromatosis in pregnancy.", "content": "Neurofibromatosis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197580"} {"pmid": "4197582", "title": "Photon fluence calculations for estimating dose distribution in the thorax.", "content": "Photon fluence calculations for estimating dose distribution in the thorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197582"} {"pmid": "4197581", "title": "Effects of Ancrod (Arvin) in mice: studies of plasma fibrinogen and fibrinolytic activity.", "content": "Effects of Ancrod (Arvin) in mice: studies of plasma fibrinogen and fibrinolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197581"} {"pmid": "4197583", "title": "The control of radiation caries.", "content": "The control of radiation caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197583"} {"pmid": "4197584", "title": "Epilepsy following cerebral abscess. A clinical and EEG study of 70 patients.", "content": "Epilepsy following cerebral abscess. A clinical and EEG study of 70 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197584"} {"pmid": "4197585", "title": "Generalized sharp and slow wave complexes. Associated clinical features and long-term follow-up.", "content": "Generalized sharp and slow wave complexes. Associated clinical features and long-term follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197585"} {"pmid": "4197586", "title": "The mechanism of drainage of the cerebrospinal fluid.", "content": "The mechanism of drainage of the cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197586"} {"pmid": "4197591", "title": "Histological changes of the pituitary gland in cockerels bearing basal hypothalamic lesions and demonstration of its anti-HCG immunofluorescence reacting cells.", "content": "Histological changes of the pituitary gland in cockerels bearing basal hypothalamic lesions and demonstration of its anti-HCG immunofluorescence reacting cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197591"} {"pmid": "4197592", "title": "Effect of glomerulopressin, oxytocin, and norepinephrine on glomerular pressure in the toad.", "content": "Effect of glomerulopressin, oxytocin, and norepinephrine on glomerular pressure in the toad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197592"} {"pmid": "4197593", "title": "Failure of mammalian TRH to stimulate thyroid function in the lungfish.", "content": "Failure of mammalian TRH to stimulate thyroid function in the lungfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197593"} {"pmid": "4197594", "title": "Results from evaluating a Canadian regional mental health program.", "content": "Results from evaluating a Canadian regional mental health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197594"} {"pmid": "4197596", "title": "Fallcies in using length-of-stay and rturn rates as measure of success.", "content": "Fallcies in using length-of-stay and rturn rates as measure of success.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197596"} {"pmid": "4197595", "title": "The unit system: current staff attitudes and future directions.", "content": "The unit system: current staff attitudes and future directions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197595"} {"pmid": "4197597", "title": "Isolation and characterization of a rabbit adrenal autoantigen.", "content": "Isolation and characterization of a rabbit adrenal autoantigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197597"} {"pmid": "4197598", "title": "Physicochemical characterization and isolation of rabbit kidney-specific autoantigens.", "content": "Physicochemical characterization and isolation of rabbit kidney-specific autoantigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197598"} {"pmid": "4197599", "title": "Isolation and characterization of a rabbit non-tissue specific autoantigen which is shared by kidney, heart, adrenal and liver.", "content": "Isolation and characterization of a rabbit non-tissue specific autoantigen which is shared by kidney, heart, adrenal and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197599"} {"pmid": "4197604", "title": "Identification of human reagins isolated with immunosorbent as IgE.", "content": "Identification of human reagins isolated with immunosorbent as IgE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197604"} {"pmid": "4197605", "title": "Induced homocytotropic antibody to bovine serum albumin in nonatopic dogs.", "content": "Induced homocytotropic antibody to bovine serum albumin in nonatopic dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197605"} {"pmid": "4197606", "title": "Linkage of thyroxine-binding globulin deficiency to other X-chromosome loci.", "content": "Linkage of thyroxine-binding globulin deficiency to other X-chromosome loci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197606"} {"pmid": "4197608", "title": "Location of inexchangeable sodium in the nucleus and cytoplasm of oocytes of Bufo bufo exposed to sodium-free solutions.", "content": "Location of inexchangeable sodium in the nucleus and cytoplasm of oocytes of Bufo bufo exposed to sodium-free solutions. 1. In oocytes exposed to Ringer solution in which Li substitutes for Na, 13-62% Na is inexchangeable with Li.2. Nuclei of oocytes isolated by dissection in salt solutions swell irrespective of the concentration or ionic components of the solution. When isolated in 4% bovine albumin solutions, swelling is negligible.3. When the nuclei of cells exposed to Li are isolated in 4% albumin solution, less than 6% of the inexchangeable Na is found in the nucleus, while 36-88% of it is found in the cytoplasmic fragments remaining after removal of the nucleus.4. When a Li-exposed cell is crushed in a cellophane bag and dialysed against Ringer or Li-substituted Ringer, 86-92% of the inexchangeable Na diffuses out.5. It thus appears that the inexchangeable Na is located almost entirely in the cytoplasm and hardly at all in the nucleus, and is not bound to macromolecules within the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197608"} {"pmid": "4197609", "title": "An evaluation of combined routes of antibiotic administration in vascular reconstructive surgery. A study of local plus parenteral administration of cephaloridine in dogs.", "content": "An evaluation of combined routes of antibiotic administration in vascular reconstructive surgery. A study of local plus parenteral administration of cephaloridine in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197609"} {"pmid": "4197607", "title": "Biosynthesis of prostaglandin E 2 in human skin: subcellular localization and inhibition by unsaturated fatty acids and anti-inflammatory drugs.", "content": "Biosynthesis of prostaglandin E 2 in human skin: subcellular localization and inhibition by unsaturated fatty acids and anti-inflammatory drugs. The biosynthesis of prostaglandin E(2) (PGE(2)) from [1-(14)C]arachidonic acid has been demonstrated in homogenates and subcellular fractions of human epidermis. This biosynthetic capacity is localized in the microsomal fraction, indicating the presence of an active prostaglandin synthetase system associated with membranes of the skin. The incorporation of (14)C from [1-(14)C]arachidonic acid into PGE(2) by the microsomal fraction was enhanced by EDTA. This apparent increase in (14)C incorporation into PGE(2) in the presence of EDTA could be due at least in part to its chelating properties of removing the divalent cations in the homogenate that enhance the selective formation of PGF(2alpha) and the suppression of the activity of epidermal phospholipase A, which causes the release of nonradioactive fatty acid precursors from endogenous phospholipids. This study has also demonstrated that the formation of PGE(2) from arachidonic acid by the microsomal fraction from human skin could be inhibited by polyunsaturated fatty acids, suggesting a possible regulatory role of fatty acids released from endogenous phospholipids on prostaglandin synthesis in this tissue. The inhibitory effects of some anti-inflammatory drugs on skin microsomal prostaglandin synthetase were also demonstrated in these studies. Results from these studies indicate that the skin is therefore a useful tissue for the study of mechanisms of prostaglandin biosynthesis and the mode of action of various anti-inflammatory drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197607"} {"pmid": "4197613", "title": "Asthma in childhood.", "content": "Asthma in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197613"} {"pmid": "4197612", "title": "Diabetic ketoacidosis in children.", "content": "Diabetic ketoacidosis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197612"} {"pmid": "4197614", "title": "The aminoacidopathies.", "content": "The aminoacidopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197614"} {"pmid": "4197615", "title": "Enzyme blocking in neuro-ophthalmology as tools and diseases.", "content": "Enzyme blocking in neuro-ophthalmology as tools and diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197615"} {"pmid": "4197616", "title": "The role of immune reactions in viral encephalitis.", "content": "The role of immune reactions in viral encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197616"} {"pmid": "4197618", "title": "Nystagmographical studies in Aland eye disease.", "content": "Nystagmographical studies in Aland eye disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197618"} {"pmid": "4197617", "title": "A unifying concept of idiopathic epilepsy.", "content": "A unifying concept of idiopathic epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197617"} {"pmid": "4197619", "title": "The use of animal models for the study of aminoacidopathies.", "content": "The use of animal models for the study of aminoacidopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197619"} {"pmid": "4197624", "title": "Contraction of isolated smooth-muscle cells--structural changes.", "content": "Contraction of isolated smooth-muscle cells--structural changes. The contraction of isolated smooth-muscle cells has been correlated with evagination of the cell membrane, a marked change in myofilament orientation, and a decrease in cellular volume. Both localized and full contractions have been elicited in the same cell by varying the intensity of electrical stimulation. These results may be explained by a model of the smooth-muscle cell in which the contractile apparatus extends between attachment sites on the cell membrane that are relatively closely spaced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197624"} {"pmid": "4197625", "title": "A protein that binds specifically to the M-line of skeletal muscle is identified as the muscle form of creatine kinase.", "content": "A protein that binds specifically to the M-line of skeletal muscle is identified as the muscle form of creatine kinase. Published information on the properties of two proteins from chicken muscle, creatine kinase (MM-creatine kinase) and an M-line protein, suggested that they might be identical molecules. Different published procedures were used to purify the two proteins to homogeneity, and the properties of the two preparations were compared. Creatine kinase specific activity increased during purification of M-line protein, reaching a value comparable to that of purified MM-creatine kinase. The two proteins migrated identically in two electrophoretic systems and, after electrophoresis, both could be stained for creatine kinase activity. Double immunodiffusion tests with antibody prepared against MM-creatine kinase established the serological identity of the two protein preparations. Immunofluorescent studies showed that antiserum against MM-creatine kinase was bound in a regular pattern at the centers of the A-band regions of isolated myofibrils. These data show conclusively that the M-line protein and MM-creatine kinase are identical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197625"} {"pmid": "4197626", "title": "Preservation of normal behavior by enucleated cells in culture.", "content": "Preservation of normal behavior by enucleated cells in culture. BHK-21 fibroblasts and BSC-1 epithelial cells were enucleated with cytochalasin B. The enucleated cells were trypsinized and replated; their subsequent behavior was monitored by light optical techniques. The results demonstrate that the information necessary for attachment, spreading, shape formation, pinocytosis, contact inhibition, and cell locomotion is present in enucleated cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197626"} {"pmid": "4197627", "title": "Repeated DNA sequences in the heterochromatic Y chromosome of adult Drosophila melanogaster.", "content": "Repeated DNA sequences in the heterochromatic Y chromosome of adult Drosophila melanogaster. DNA isolated from Drosophila melanogaster adults (XX, XY, XXY, XYY) was used in DNA-DNA hybridization experiments on nitrocellulose filters. Filter-bound DNA of \"high-heterochromatin\" flies (those with one or more Y chromosomes) is more effective in forming hybrid duplexes than is XX DNA. The quantitative difference in hybridization efficiency is due primarily to molecules with a relatively high thermal stability (duplexes that dissociate in the temperature range 80-90 degrees ). Hybridization experiments with DNA samples that have been fractionated into reiterated and unique portions show that the majority of the hybrid duplexes formed involve reiterated DNA. A small, but highly specific, interaction of unique DNA sequences has also been detected in our experiments. These data indicate that a class of repeated DNA sequences is associated with the constitutive heterochromatin, specifically with the Y chromosome of D. melanogaster. Evidence is presented that this same class of molecules, or very similar ones, is to be found in other portions of the genome, presumably in X-chromosomal or centromeric heterochromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197627"} {"pmid": "4197628", "title": "Hydrophobic chromatography: use for purification of glycogen synthetase.", "content": "Hydrophobic chromatography: use for purification of glycogen synthetase. A homologous series of omega-aminoalkylagaroses [Sepharose-NH(CH(2))(n)NH(2)] that varied in the length of their hydrocarbon side chains was synthesized. This family of agaroses was used for a new type of chromatography, in which retention of proteins is achieved mainly through lipophilic interactions between the hydrocarbon side chains on the agarose and accessible hydrophobic pockets in the protein. When an extract of rabbit muscle was subjected to chromatography on these modified agaroses, the columns with short \"arms\" (n = 2 and n = 3) excluded glycogen synthetase (EC 2.4.1.11), but the enzyme was retained on delta-aminobutyl-agarose (n = 4), from which it could be eluted with a linear NaCl gradient. Higher members of this series (e.g., n = 6) bind the synthetase so tightly that it can be eluted only in a denatured form. A column of delta-aminobutyl-agarose, which retained the synthetase, excluded glycogen phosphorylase (EC 2.4.1.1), which in this column series and under the same conditions requires side chains 5-(or 6)-carbon-atoms long for retention. Therefore, it is possible to isolate glycogen synthetase by passage of muscle extract through delta-aminobutyl-agarose, then to extract phosphorylase by subjecting the excluded proteins to chromatography on omega-aminohexyl-agarose (n = 6). On a preparative scale, the synthetase (I form) was purified 25- to 50-fold in one step. This paper describes some basic features and potential uses of hydrophobic chromatography. The relevance of the results presented here to the design and use of affinity chromatography columns is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197628"} {"pmid": "4197629", "title": "Inactive enzyme molecules in aging mice: liver aldolase.", "content": "Inactive enzyme molecules in aging mice: liver aldolase. Evidence is presented that there is a considerable accumulation of inactive fructose-1,6-diphosphate aldolase (EC 4.1.2.7) in the liver of senescent mice. Liver aldolase was purified from 3-month-old mice and used to immunize rabbits. It was demonstrated with the monospecific antibody thus produced that the liver aldolase of young adult (3 month) and aged (31 month) mice are antigenically identical. With the antibody, inactive enzyme molecules (crossreacting material) in liver homogenate of old mice were detected. The liver aldolase of senescent mice had half as much active enzyme per mg of protein, as well as per antigenic unit, as did the liver aldolase of young adult mice. The accumulation of faulty enzyme molecules may be one of the causes of debilitation leading to senescence and death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197629"} {"pmid": "4197630", "title": "Functional correspondence between 30S ribosomal proteins of Escherichia coli and Bacillus stearothermophilus.", "content": "Functional correspondence between 30S ribosomal proteins of Escherichia coli and Bacillus stearothermophilus. 30S ribosomal proteins from Bacillus stearothermophilus (B. proteins) have been fractionated and characterized with respect to their ability to replace various E. coli 30S proteins (E. proteins) in the E. coli 30S ribosome reconstitution system. The functional counterparts of all the E. proteins, except S1, S6, S9, and S13, have been tested. In all cases, B. proteins can substitute for E. proteins. Several purified B. proteins are chemically different from their functionally homologous E. proteins. Five B. proteins are immunochemically related to E. proteins; this set includes two proteins that could not be tested in the reconstitution system (S9 and S13). Thus most, if not all, of the E. proteins have functionally equivalent counterparts among B. proteins, even though properties of the two ribosomes are different in several respects. These results suggest that the fundamental structural organization of ribosomes may be the same throughout prokaryotic organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197630"} {"pmid": "4197631", "title": "Occurrence of specific pollutants in fish in the Forth and Tay estuaries.", "content": "Occurrence of specific pollutants in fish in the Forth and Tay estuaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197631"} {"pmid": "4197632", "title": "Algal metabolism and water pollution in the Tay region.", "content": "Algal metabolism and water pollution in the Tay region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197632"} {"pmid": "4197634", "title": "cis-Dichlorodiammineplatinum(II) (NSC-119 875): preclinical toxicologic evaluation of intravenous injection in dogs, monkeys and mice.", "content": "cis-Dichlorodiammineplatinum(II) (NSC-119 875): preclinical toxicologic evaluation of intravenous injection in dogs, monkeys and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197634"} {"pmid": "4197635", "title": "Relationship of the structure of mescaline and seven analogs to toxicity and behavior in five species of laboratory animals.", "content": "Relationship of the structure of mescaline and seven analogs to toxicity and behavior in five species of laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197635"} {"pmid": "4197639", "title": "Depression of bone marrow and thrombocytopenia associated with chrysotherapy.", "content": "Depression of bone marrow and thrombocytopenia associated with chrysotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197639"} {"pmid": "4197638", "title": "Multiple DNA polymerases displayed by isoelectric focusing.", "content": "Multiple DNA polymerases displayed by isoelectric focusing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197638"} {"pmid": "4197640", "title": "Rapid, direct tissue culture test for toxigenicity of Corynebacterium diphtheriae.", "content": "Rapid, direct tissue culture test for toxigenicity of Corynebacterium diphtheriae. A method for testing toxigenicity of Corynebacterium diphtheriae in tissue culture is described. The technique, called the colony overlay test (COT), involves inoculating material from an isolated colony of C. diphtheriae to a small area on the surface of an agar medium which overlays a monolayer of toxin-susceptible HeLa cells. If toxin is produced during incubation at 37 C, it diffuses to the tissue monolayer and destroys the cells below the inoculation site. Twenty-four hours after inoculation, organisms are killed and tissue cells are fixed with formaldehyde. The agar overlay is then removed, and the monolayer is stained with crystal violet. Toxin-affected areas fail to stain or stain poorly. A second plate with antitoxin incorporated in the overlay serves as a control for specificity. Forty-eight strains of C. diphtheriae were tested by the COT, guinea pig, and in vitro, gel diffusion tests. The COT is as specific as the other two tests, is easy to read, and can be used to test large numbers of isolates for toxin action more conveniently than by animal inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197640"} {"pmid": "4197641", "title": "Production of staphylococcal enterotoxins A, B, and C in colloidal dispersions.", "content": "Production of staphylococcal enterotoxins A, B, and C in colloidal dispersions. Larger amounts of enterotoxin were produced when Staphylococcus aureus S-6 was grown under still (nonshaken) conditions in a medium that was a paste or gel than were produced in a liquid dispersion with the same colloidal ingredient or in control basal broth (4% NZ Amine-NAK containing 50 mug of thiamine per 100 ml and 1 mg of niacin per 100 ml). Four colloidal ingredients were used which had been previously demonstrated to not support enterotoxin production in buffer. The effect of the type of dispersion occurred earlier than that of the colloidal ingredient, but interactions were found. This effect was not observed when the cells were grown with aeration (shaken). Four other strains of S. aureus followed a similar pattern for enterotoxins A, B, and C, although liquid and paste with cornstarch and carrageenan were the only media compared to the control broth. Enterotoxins A and B were produced earlier by S. aureus S-6, and much greater quantities of enterotoxins were produced for all strains when incubated shaken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197641"} {"pmid": "4197633", "title": "Differential activity of homologous chromosome loci in ontogenesis.", "content": "Differential activity of homologous chromosome loci in ontogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197633"} {"pmid": "4197642", "title": "The effects of certain inorganic ions on in vitro porphyrin--heme formation.", "content": "The effects of certain inorganic ions on in vitro porphyrin--heme formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197642"} {"pmid": "4197644", "title": "Surface lipid of cells of Pseudomonas aeruginosa and its relation to gentamicin-resistance.", "content": "Surface lipid of cells of Pseudomonas aeruginosa and its relation to gentamicin-resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197644"} {"pmid": "4197643", "title": "A comparison between immunochemical and physical chemical analyses of the molecular size of urinary proteins.", "content": "A comparison between immunochemical and physical chemical analyses of the molecular size of urinary proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197643"} {"pmid": "4197646", "title": "Extrageniculostriate vision in the monkey. IV. Critical structures for light vs. no-light discrimination.", "content": "Extrageniculostriate vision in the monkey. IV. Critical structures for light vs. no-light discrimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197646"} {"pmid": "4197660", "title": "The acetylcholinesterase of Bungarus fasciatus venom.", "content": "The acetylcholinesterase of Bungarus fasciatus venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197660"} {"pmid": "4197661", "title": "Immunological studies on globular and elongated forms of electric eel acetylcholinesterase. Effects of hydrolytic enzymes.", "content": "Immunological studies on globular and elongated forms of electric eel acetylcholinesterase. Effects of hydrolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197661"} {"pmid": "4197665", "title": "Thyrotrophin secretion from rat pituitary autografts infused with synthetic thyrotrophin releasing factor.", "content": "Thyrotrophin secretion from rat pituitary autografts infused with synthetic thyrotrophin releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197665"} {"pmid": "4197666", "title": "Pyourachus: an unusual surgical problem.", "content": "Pyourachus: an unusual surgical problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197666"} {"pmid": "4197667", "title": "A new method of fixation of silicone rubber catheters for long-term hyperalimentation.", "content": "A new method of fixation of silicone rubber catheters for long-term hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197667"} {"pmid": "4197668", "title": "Adjuvants and the reticuloendothelial system. The recall phenomenon of the stimulatory effects of adjuvants with homologous antigen.", "content": "Adjuvants and the reticuloendothelial system. The recall phenomenon of the stimulatory effects of adjuvants with homologous antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197668"} {"pmid": "4197669", "title": "Mouse IgM antibodies. I. Quantitation of mouse anti-sheep erythrocyte IgM by absorption and radial immunodiffusion.", "content": "Mouse IgM antibodies. I. Quantitation of mouse anti-sheep erythrocyte IgM by absorption and radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197669"} {"pmid": "4197670", "title": "Mouse IgM antibodies. II. Variation in mouse specific sheep erythrocyte antibody and total IgM.", "content": "Mouse IgM antibodies. II. Variation in mouse specific sheep erythrocyte antibody and total IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197670"} {"pmid": "4197671", "title": "Still disease in adults. A cause of prolonged undiagnosed fever.", "content": "Still disease in adults. A cause of prolonged undiagnosed fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197671"} {"pmid": "4197662", "title": "Treatment of pelvic inflammatory disease in an urban emergency service.", "content": "Treatment of pelvic inflammatory disease in an urban emergency service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197662"} {"pmid": "4197672", "title": "Epilepsy and contact sports. Factors contraindicating participation.", "content": "Epilepsy and contact sports. Factors contraindicating participation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197672"} {"pmid": "4197673", "title": "Protein calorie malnutrition and intellectual competence.", "content": "Protein calorie malnutrition and intellectual competence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197673"} {"pmid": "4197675", "title": "Oral care in radiation therapy.", "content": "Oral care in radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197675"} {"pmid": "4197677", "title": "A procedure for chronic microelectrode recording from cerebellar cortex in the awake cat and monkey.", "content": "A procedure for chronic microelectrode recording from cerebellar cortex in the awake cat and monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197677"} {"pmid": "4197679", "title": "Management of gastrointestinal fistulas with parenteral hyperalimentation.", "content": "Management of gastrointestinal fistulas with parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197679"} {"pmid": "4197678", "title": "Comparative effects of dose protraction and residual injury in dogs and monkeys.", "content": "Comparative effects of dose protraction and residual injury in dogs and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197678"} {"pmid": "4197692", "title": "Symptomatic prognosis in patients with idiopathic hypertrophic subaortic stenosis (IHSS).", "content": "Symptomatic prognosis in patients with idiopathic hypertrophic subaortic stenosis (IHSS).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197692"} {"pmid": "4197694", "title": "Identification of ureteral ligation during gynecologic operations.", "content": "Identification of ureteral ligation during gynecologic operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197694"} {"pmid": "4197693", "title": "Studies on uterine flushings in the baboon. I. Method of collection, cellular composition, and protein electrophoretic profiles in animals with and without intrauterine contraceptive devices.", "content": "Studies on uterine flushings in the baboon. I. Method of collection, cellular composition, and protein electrophoretic profiles in animals with and without intrauterine contraceptive devices. Uterine fluid was collected from 11 mature baboons, probably parous, using a \"Barbaro\" device, developed for sampling human endometrial cells. Disc electrophoresis was carried out on properly prepared concentrated supernatant fluid. The electrophoretic patterns did not vary markedly between animals or after fitting of an IUD. The most marked differences from plasma patterns were in the middle bands (Bands 8-12). Cytological examination of the precipitate showed the presence of elongated epithelial cells resembling those lining the uterine lumen, cells similar to endometrial stromal cells, large squamous cells resembling cornified vaginal cells, polymorphonuclearleukocytes, which increased as a response to the insertion of an IUD, mononuclear cells and occasional erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197693"} {"pmid": "4197695", "title": "Immunoglobulin levels and liver function tests in normal and toxemic pregnancies.", "content": "Immunoglobulin levels and liver function tests in normal and toxemic pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197695"} {"pmid": "4197696", "title": "The pathogenesis of placental infarction. II. An experimental study in the rhesus monkey placenta.", "content": "The pathogenesis of placental infarction. II. An experimental study in the rhesus monkey placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197696"} {"pmid": "4197697", "title": "An experimental model of pulmonary arterial granulomatous inflammation.", "content": "An experimental model of pulmonary arterial granulomatous inflammation. An experimental method to investigate pulmonary granuloma formation in the guinea pig was established. Animals sensitized to human serum albumin (HSA) and challenged intravenously with HSA covalently linked to Sepharose 2B beads developed a specific granulomatous response. This intense pulmonary arterial, focally necrotizing, but mainly granulomatous inflammatory reaction developed 5 to 7 days after the administration of the HSA-bead conjugate. Unsensitized animals did not show such extensive inflammation, but rather exhibited a typical foreign body reaction to the bead. In both the experimental and control groups, the inflammatory response was indistinguishable at 14 and 21 days. Thus the initial acute inflammatory reaction was seen only in specifically sensitized animals. On the other hand, HSA alone produced no demonstrable inflammatory lesion. These observations suggest that locally retained antigen may trigger antigen-specific T (thymus-dependent) lymphocytes to release mediators which contribute to granuloma formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197697"} {"pmid": "4197698", "title": "Pseudomonas aeruginosa allergy and humoral antibody-mediated hypersensitivity pneumonia.", "content": "Pseudomonas aeruginosa allergy and humoral antibody-mediated hypersensitivity pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197698"} {"pmid": "4197699", "title": "Scientific Assembly statement. The use of skin tests and serologic tests in histoplasmosis, coccidioidomycosis, and blastomycosis, 1973.", "content": "Scientific Assembly statement. The use of skin tests and serologic tests in histoplasmosis, coccidioidomycosis, and blastomycosis, 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197699"} {"pmid": "4197703", "title": "Coronary artery bypass graft haemodynamics.", "content": "Coronary artery bypass graft haemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197703"} {"pmid": "4197704", "title": "Direct determination of red cell bound antibody specificity.", "content": "Direct determination of red cell bound antibody specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197704"} {"pmid": "4197702", "title": "The effect of feeding -2-thienylalanine on phenylalanine metabolism in the rhesus monkey.", "content": "The effect of feeding -2-thienylalanine on phenylalanine metabolism in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197702"} {"pmid": "4197705", "title": "Qualitative and quantitative studies on IgG2 globulins in individual human sera with an antiserum capable of differentiating between Gm(n+) and Gm(n-) proteins.", "content": "Qualitative and quantitative studies on IgG2 globulins in individual human sera with an antiserum capable of differentiating between Gm(n+) and Gm(n-) proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197705"} {"pmid": "4197708", "title": "Rapid fixation of the left ventricle: continuous angiographic and dynamic recordings.", "content": "Rapid fixation of the left ventricle: continuous angiographic and dynamic recordings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197708"} {"pmid": "4197709", "title": "Synthesis of actinomycin D lactam, [1',1'-bis(L-threo- , -diaminobutyric acid)]actinomycin D.", "content": "Synthesis of actinomycin D lactam, [1',1'-bis(L-threo- , -diaminobutyric acid)]actinomycin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197709"} {"pmid": "4197710", "title": "Competitive binding to multiple stereospecific binding agents as a means of verifying the identity of a ligand application to cortisol in human umbilical cord blood.", "content": "Competitive binding to multiple stereospecific binding agents as a means of verifying the identity of a ligand application to cortisol in human umbilical cord blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197710"} {"pmid": "4197711", "title": "Transmissible mink encephalopathy in carnivores: clinical, light and electron microscopic studies in raccons, skunks and ferrets.", "content": "Transmissible mink encephalopathy in carnivores: clinical, light and electron microscopic studies in raccons, skunks and ferrets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197711"} {"pmid": "4197715", "title": "Generalized plane xanthomata with macroglobulinaemia.", "content": "Generalized plane xanthomata with macroglobulinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197715"} {"pmid": "4197716", "title": "Reiter's disease and psoriasis.", "content": "Reiter's disease and psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197716"} {"pmid": "4197722", "title": "An automated system for the regulation and medical review of long-term care facilities and patients.", "content": "An automated system for the regulation and medical review of long-term care facilities and patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197722"} {"pmid": "4197723", "title": "Preparation of L-tyrosine-ring- 14 C, L-DOPA-ring- 14 C and related metabolites.", "content": "Preparation of L-tyrosine-ring- 14 C, L-DOPA-ring- 14 C and related metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197723"} {"pmid": "4197724", "title": "Gas-liguid chromatography of parathion metabolites as a sensitive index of induction of liver microsomal mixed-function oxidases.", "content": "Gas-liguid chromatography of parathion metabolites as a sensitive index of induction of liver microsomal mixed-function oxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197724"} {"pmid": "4197725", "title": "Estimation of eater-extractable Ca in chicken breast muscle by atomic absorption.", "content": "Estimation of eater-extractable Ca in chicken breast muscle by atomic absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197725"} {"pmid": "4197721", "title": "Central effects of sympathomimetic amines.", "content": "Central effects of sympathomimetic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197721"} {"pmid": "4197726", "title": "An assay for the endonucleolytic clevage of RNA to large oligonucleotides.", "content": "An assay for the endonucleolytic clevage of RNA to large oligonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197726"} {"pmid": "4197727", "title": "Determination of the Krebs cycle related keto acids of microorganisms by capillary gas chromatography on glass columns.", "content": "Determination of the Krebs cycle related keto acids of microorganisms by capillary gas chromatography on glass columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197727"} {"pmid": "4197728", "title": "Fine structural changes in the placental membrane of the marmoset with increasing gestational age.", "content": "Fine structural changes in the placental membrane of the marmoset with increasing gestational age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197728"} {"pmid": "4197729", "title": "Immunologic analysis of noncollagen proteins of human skin.", "content": "Immunologic analysis of noncollagen proteins of human skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197729"} {"pmid": "4197730", "title": "Antibacterial action of complexing compounds. The influence of disodium versenate on microorganisms in vitro.", "content": "Antibacterial action of complexing compounds. The influence of disodium versenate on microorganisms in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197730"} {"pmid": "4197732", "title": "Local antigenic stimulation of guinea-pig mammary gland.", "content": "Local antigenic stimulation of guinea-pig mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197732"} {"pmid": "4197731", "title": "The distribution of blood, serum protein and enzyme groups in a series of Lebanese in Australia.", "content": "The distribution of blood, serum protein and enzyme groups in a series of Lebanese in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197731"} {"pmid": "4197733", "title": "Mechanisms of transfer on immunoglobulins into mammary secretion of ewes.", "content": "Mechanisms of transfer on immunoglobulins into mammary secretion of ewes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197733"} {"pmid": "4197734", "title": "Comparisons of immunoglobulin secretion in the salivary and mammary glands of sheep.", "content": "Comparisons of immunoglobulin secretion in the salivary and mammary glands of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197734"} {"pmid": "4197735", "title": "The diagnosis of tuberculosis in cattle with special reference to bovine PPD tuberculin.", "content": "The diagnosis of tuberculosis in cattle with special reference to bovine PPD tuberculin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197735"} {"pmid": "4197737", "title": "The metabolism of ethyl 4-(3,4,5-Trimethoxycinnamoyl) piperazinyl acetate in rats and dogs.", "content": "The metabolism of ethyl 4-(3,4,5-Trimethoxycinnamoyl) piperazinyl acetate in rats and dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197737"} {"pmid": "4197739", "title": "Modification by sodium salicylate and paraaminosalyicylic acid of the protein binding and antimycobacterial effect of isoniazid in vitro.", "content": "Modification by sodium salicylate and paraaminosalyicylic acid of the protein binding and antimycobacterial effect of isoniazid in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197739"} {"pmid": "4197746", "title": "The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas.", "content": "The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197746"} {"pmid": "4197747", "title": "Serum autoantibodies and immunoglobulins in hepatitis-associated antigen (HAA)-positive and -negative liver disease.", "content": "Serum autoantibodies and immunoglobulins in hepatitis-associated antigen (HAA)-positive and -negative liver disease. Serum immunoglobulin G, A, and M and serum antinuclear, mitochondrial, and smooth muscle antibody have been measured in 223 patients with hepatitis-associated antigen (HAA)-positive and -negative acute and chronic liver disease. In patients with acute hepatitis, chronic persistent hepatitis, and primary liver cell carcinoma, these indices failed to show any significant differences. However, in the group with chronic aggressive hepatitis the patients who were HAA negative had significantly higher levels of serum IgG, much higher titres of smooth muscle antibody, and often antinuclear and mitochondrial antibodies which were not found in the HAA-positive patients from this group. This suggests that different pathogenic mechanisms may be operative in HAA-positive and -negative chronic aggressive hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197747"} {"pmid": "4197749", "title": "Isolation of Rickettsia rickettsi in primary bone marrow cell and circulating monocyte cultures derived from experimentally infected guinea pigs.", "content": "Isolation of Rickettsia rickettsi in primary bone marrow cell and circulating monocyte cultures derived from experimentally infected guinea pigs. Rickettsia rickettsi was isolated and propagated in primary cell cultures derived from experimentally infected guinea pigs. Organisms were recognized as early as 3 days after cultures were initiated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197749"} {"pmid": "4197748", "title": "Gel filtration studies on immunoreactive gastrin in serum from Zollinger-Ellison patients.", "content": "Gel filtration studies on immunoreactive gastrin in serum from Zollinger-Ellison patients. Sera from 15 patients with the Zollinger-Ellison syndrome were subjected to gel filtration on Sephadex G-50 superfine columns (10 x 2000 mm). The concentration of gastrin in the effluent was determined by a sensitive radioimmunoassay. Immunoreactive gastrin was eluted in four components in 14 sera. (1) Component I, eluted in the same position as proinsulin, constituted 9.7 +/- 1.2 (mean +/- SEM)% of the total immunoreactivity. (2) Component II (;big gastrin') eluted between proinsulin and insulin constituted 57.8 +/- 4.1% (mean +/- SEM) of immunoreactive gastrin. In three sera with the highest concentration of gastrin, component II appeared biphasic. (3) Component III (;little gastrin') was distributed in two peaks; the first one eluted in the same position as the heptadecapeptide gastrin II made up 17.4 +/- 2.7 (mean +/- SEM)% of the total immunoreactivity; the second one eluted in the same position as gastrin I constituted 9.5 +/- 1.3 (mean +/- SEM)%. (4) Component IV (;minigastrin') was eluted immediately before the salt peak and constituted 5.6 +/- 1.4 (mean +/- SEM)%. In one serum only components I and II were present. After incubation with trypsin all immunoreactivity in components I and II was converted to heptadecapeptide-like gastrins.The findings suggest that immunoreactive gastrin in serum from Zollinger-Ellison patients is circulating in at least four components of different molecular size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197748"} {"pmid": "4197751", "title": "The pharmaceutical market and prescription drugs in the Federal Republic of Germany: cross-national comparisons.", "content": "The pharmaceutical market and prescription drugs in the Federal Republic of Germany: cross-national comparisons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197751"} {"pmid": "4197750", "title": "Multiplicity of Scrapie virus in infected mouse spleen cells in vivo.", "content": "Multiplicity of Scrapie virus in infected mouse spleen cells in vivo. Subpopulations of spleen cells from scrapie virus-infected mice were used to determine the average virus content of infected cells in vivo at a time when virus was rapidly increasing in titer in lymphoreticular tissues. Comparison of the mean lethal doses of lysed to intact cells indicated averages of 2 to 6 infectious units per infected cell. In another experiment, preparations of cytoplasmic nucleic acids extracted from spleen cells of infected mice had no detectable infectivity, which suggests that the transmissible form of the virus is not a free nucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197750"} {"pmid": "4197754", "title": "Immunologic response of man to group B meningococcal polysaccharide vaccines.", "content": "Immunologic response of man to group B meningococcal polysaccharide vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197754"} {"pmid": "4197753", "title": "A method for measurement of antibiotics in human interstitial fluid.", "content": "A method for measurement of antibiotics in human interstitial fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197753"} {"pmid": "4197755", "title": "Shigellosis due to Shigella dysenteriae. 1. Relative importance of mucosal invasion versus toxin production in pathogenesis.", "content": "Shigellosis due to Shigella dysenteriae. 1. Relative importance of mucosal invasion versus toxin production in pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197755"} {"pmid": "4197756", "title": "Effect of rifampicin on delayed-hypersensitivity reactions.", "content": "Effect of rifampicin on delayed-hypersensitivity reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197756"} {"pmid": "4197757", "title": "Adherence of Neisseria gonorrhoeae to urethral mucosal cells: an electron-microscopic study of human gonorrhea.", "content": "Adherence of Neisseria gonorrhoeae to urethral mucosal cells: an electron-microscopic study of human gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197757"} {"pmid": "4197758", "title": "Treatment of funnel-web spider bite.", "content": "Treatment of funnel-web spider bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197758"} {"pmid": "4197760", "title": "Mutagenic DNA polymerase in B. subtilis.", "content": "Mutagenic DNA polymerase in B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197760"} {"pmid": "4197761", "title": "Quantitating cholinergic receptor molecules.", "content": "Quantitating cholinergic receptor molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197761"} {"pmid": "4197762", "title": "Laboratory diagnosis of multiple sclerosis. Elevation of immunoglobulin G in cerebrospinal fluid.", "content": "Laboratory diagnosis of multiple sclerosis. Elevation of immunoglobulin G in cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197762"} {"pmid": "4197764", "title": "Diagnosis of meningococcal arthritis by immunoelectrophoresis of synovial fluid.", "content": "Diagnosis of meningococcal arthritis by immunoelectrophoresis of synovial fluid. In a case of meningococcal arthritis, the organism was identified promptly through examination of synovial fluid by countercurrent immunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197764"} {"pmid": "4197765", "title": "Preparation of solid-phase immunosorbents by coupling human serum proteins to cyanogen bromide-activated agarose.", "content": "Preparation of solid-phase immunosorbents by coupling human serum proteins to cyanogen bromide-activated agarose. The method of preparing solid-phase immunosorbents by covalently attaching proteins from whole human serum to cyanogen bromide-activated agarose has been investigated to determine optimum concentrations of cyanogen bromide and protein, and the optimum pH for the maximum attachment of proteins from serum. Two systems in which the above immunosorbents have proved useful are described: the removal of antibodies to normal serum proteins from anti-hepatitis B serum and the removal of light chain antibodies from anti-human immunoglobulin M serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197765"} {"pmid": "4197766", "title": "Aflatoxin production of species and strains of the Aspergillus flavus group isolated from field crops.", "content": "Aflatoxin production of species and strains of the Aspergillus flavus group isolated from field crops. Peanuts, cottonseed, rice, and sorghum from Texas were sampled over a 3-year period. To insure adequate isolation of alfatoxin-producing species of fungi, low-quality lots were sampled at a rate greater than their respective proportional representation. Aflatoxins were found each year in peanut and cottonseed and were found in 2 of 3 years in rice and sorghum. Aflatoxins were detected in all four crops. The Aspergillus flavus group was much more prevalent in peanut and rice than in cottonseed and sorghum. Of the isolates of the A. flavus group, 96% from peanuts, 79% from cottonseed, 49% from sorghum, and 35% from rice produced aflatoxins. The average toxin production of isolates from rice was much less than that from peanuts, cottonseed, or sorghum. More than 90% of all isolates of the A. flavus group were identified as the species A. flavus. A. parasiticus was isolated from all four crops. Only A. parasiticus produced aflatoxin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197766"} {"pmid": "4197768", "title": "Control of surface wound infection: skin versus synthetic grafts.", "content": "Control of surface wound infection: skin versus synthetic grafts. Auto-, iso-, or xenografts of skin and synthetics placed on surface wounds freshly contaminated with Pseudomonas aeruginosa stabilizes the wound bacterial population in rats over a 24-h period. When these wounds contained a bacterial contamination established for 24 h prior to grafting, only skin and the synthetic polyhydroxyethylmethacrylate were effective in lowering the initial bacterial concentration. Polyurethane foam and nylon velour were not effective in the established infection model. Skin placed on a contaminated wound for 2 h or longer appeared to equilibrate with the underlying muscle so that the bacterial count per milligram of skin was similar to that of the muscle. It was suggested that this preparation would be useful to obtain an estimate of surface contamination without biopsy of the infected muscle. Skin grafts in place for 2 h significantly lowered the bacterial count in a wound with an established infection. A second decrease occurred between 4 and 24 h after grafting. Histological studies of contaminated and exposed panniculus muscle showed that leukocytes tend to migrate from the muscle surface to its base. Skin grafts and polyhydroxyethylmethacrylate appear to reverse the white cell migration so that the cells move toward the surface of the muscle with preservation of normal staining characteristics in the muscle. It is suggested that this alteration in cell movement after graft application might modify the white cell function and result in a greater bactericidal activity. Apparently, grafts lower bacterial levels in an established infection by modifying the host response to the surface contamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197768"} {"pmid": "4197769", "title": "Culture of Ethiopian strains of Borrelia recurrentis.", "content": "Culture of Ethiopian strains of Borrelia recurrentis. A number of standard bacteriological media with supplements were tested for their ability to support in vitro growth of Ethiopian strains of Borrelia recurrentis. Propagation of 18 out of 21 strains occurred in Trypticase soy yeast broth to which bovine albumin (fraction V), N-acetyl glucosamine, and sodium pyruvate had been added. This medium supported a population of 10(7) organisms per ml and yielded a harvest of four to five times the original inoculum during the logarithmic phase of growth. Maximal yield varied from 1.4 x 10(7) to 3.4 x 10(7) organisms per ml. Generation time in optimal media was 11.3 h. Lesser multiplication of organisms occurred in other media tested. Strains from primary cultures were infective for the green monkey. Recovery of viable organisms from subculture has not been successful.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197769"} {"pmid": "4197767", "title": "Indirect fluorescent-antibody method for the identification of Corynebacterium vaginale.", "content": "Indirect fluorescent-antibody method for the identification of Corynebacterium vaginale. The indirect fluorescent-antibody technique was employed in an attempt to develop a rapid method of identification of Corynebacterium vaginale. Six reference strains and ten clinical isolates selected on the basis of morphology and conventional biochemical tests were compared. Antisera were prepared in rabbits against the six reference strains. The most satisfactory antiserum was that prepared using strain 14018 grown diphasically (14018 Di) as the antigen. Certain of the antisera did exhibit a cross-reacting titer when reacted against Corynebacterium diptheriae, Corynebacterium xerosis, or Lactobacillus acidophilus. However, antisera adsorbed with these bacteria did not exhibit a significant decrease in titer when reacted against the homologous strain. Various other species of Corynebacterium as well as species of Nocardia, Actinomyces, Hemophilus, and Streptococcus did not fluoresce with the antisera. A specific antiserum was prepared by adsorbing anti-14018 Di with L. acidophilus. The adsorption removed the cross-reacting antibody but did not affect the staining reaction with C. vaginale strains. All reference strains and clinical isolates characterized as C. vaginale gave a definite positive reaction with the adsorbed anti-14018 Di. The specificity of the reactions was assessed by adsorbing the antiserum with the homologous strain. The data suggest that the indirect staining method will be of value in the rapid presumptive identification of C. vaginale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197767"} {"pmid": "4197771", "title": "Cicatricial pemphigoid. Immunofluorescence investigations.", "content": "Cicatricial pemphigoid. Immunofluorescence investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197771"} {"pmid": "4197770", "title": "Preservation of mycobacteria: 100 percent viability of suspensions stored at -70 C.", "content": "Preservation of mycobacteria: 100 percent viability of suspensions stored at -70 C. Our earlier studies on long-term preservation of mycobacteria have been expanded to include other species in this genus. Mycobacterium kansasii and M. marinum, like mammalian tubercle bacilli and BCG, survive much better when stored at -70 C. By statistical analysis, M. gordonae, M. scrofulaceum, M. xenopi, M. avium, M. intracellulare, M. terrae, M. fortuitum, and M. smegmatis survived equally well at -20 C or -70 C; however, viable counts of all strains stored at -20 C were always lower than those of paired suspensions stored at -70 C, suggesting that the lower temperature is preferable for prolonged storage periods. Advantages of preservation at -70 C in Tween-albumin liquid medium are: (i) 100% viability of bacterial populations for long periods, (ii) highly reproducible inocula for animal experiments, (iii) minimal clonal selection of undesirable mutants, (iv) maintenance of genetic characteristics, and (v) adaptability to a \"seed lot\" system. On the basis of available information, a discussion of lyophilization versus freezer storage is presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197770"} {"pmid": "4197772", "title": "Gold sodium thiomalate treatment of pemphigus.", "content": "Gold sodium thiomalate treatment of pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197772"} {"pmid": "4197774", "title": "The middle temporal visual area(MT)in the bushbaby, Galago senegalensis.", "content": "The middle temporal visual area(MT)in the bushbaby, Galago senegalensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197774"} {"pmid": "4197775", "title": "Acute myelomonocytic leukemia with macroglobulinemia, Bence Jones proteinuria, and hypercalcemia.", "content": "Acute myelomonocytic leukemia with macroglobulinemia, Bence Jones proteinuria, and hypercalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197775"} {"pmid": "4197776", "title": "The role of iron in bacterial infections, with special consideration of host-tubercle bacillus interaction.", "content": "The role of iron in bacterial infections, with special consideration of host-tubercle bacillus interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197776"} {"pmid": "4197780", "title": "Effects of methylmercuric chloride on the progeny of mice and rats treated before or during gestation.", "content": "Effects of methylmercuric chloride on the progeny of mice and rats treated before or during gestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197780"} {"pmid": "4197779", "title": "Metabolism and elimination of sulphite by rats, mice and nonkeys.", "content": "Metabolism and elimination of sulphite by rats, mice and nonkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197779"} {"pmid": "4197781", "title": "More meditations of MSG.", "content": "More meditations of MSG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197781"} {"pmid": "4197773", "title": "Applications of a simplified triple-test cross.", "content": "Applications of a simplified triple-test cross.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197773"} {"pmid": "4197783", "title": "Asymptomatic ossification of the posterior longitudinal ligament of the cervical spine. Incidence and roentgenographic findings.", "content": "Asymptomatic ossification of the posterior longitudinal ligament of the cervical spine. Incidence and roentgenographic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197783"} {"pmid": "4197782", "title": "Experimental autoimmune damage to rabbit male accesory glands.", "content": "Experimental autoimmune damage to rabbit male accesory glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197782"} {"pmid": "4197784", "title": "Anti-nociceptive activity of clonixin in rhesus monkeys.", "content": "Anti-nociceptive activity of clonixin in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197784"} {"pmid": "4197797", "title": "Electron microscopic and serological studies on simian virus S.A. 11 and the \"related\" O agent.", "content": "Electron microscopic and serological studies on simian virus S.A. 11 and the \"related\" O agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197797"} {"pmid": "4197798", "title": "Neurophysiology of color vision.", "content": "Neurophysiology of color vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197798"} {"pmid": "4197799", "title": "Metabolic characteristics of 241 Am in the adult baboon.", "content": "Metabolic characteristics of 241 Am in the adult baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197799"} {"pmid": "4197804", "title": "Carbonic anhydrase quantity of red blood cells in morbus basedowii.", "content": "Carbonic anhydrase quantity of red blood cells in morbus basedowii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197804"} {"pmid": "4197808", "title": "Bile reflux gastritis. Diagnosis, medical and surgical therapy.", "content": "Bile reflux gastritis. Diagnosis, medical and surgical therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197808"} {"pmid": "4197814", "title": "Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori. I. Activation reaction by the enzyme.", "content": "Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori. I. Activation reaction by the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197814"} {"pmid": "4197815", "title": "Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori. II. Purification and characterization of the enzyme.", "content": "Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori. II. Purification and characterization of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197815"} {"pmid": "4197816", "title": "Preparation of rubella virus antigens for immunodiffusion by mild extraction of infected cells with a neutral detergent.", "content": "Preparation of rubella virus antigens for immunodiffusion by mild extraction of infected cells with a neutral detergent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197816"} {"pmid": "4197817", "title": "Immunochemical studies of Sindbis virus variants.", "content": "Immunochemical studies of Sindbis virus variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197817"} {"pmid": "4197819", "title": "An absolute requirement for insulin in the control of hepatic glycogenesis by glucose.", "content": "An absolute requirement for insulin in the control of hepatic glycogenesis by glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197819"} {"pmid": "4197821", "title": "Kinetic parameters of human carbonic anhydrase B as determined from NMR linewidths of 13 C in CO 2 and HCO 3 - .", "content": "Kinetic parameters of human carbonic anhydrase B as determined from NMR linewidths of 13 C in CO 2 and HCO 3 - .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197821"} {"pmid": "4197820", "title": "Sulfhydryl reactivity of organic nitrates: biochemical basis for inhibition of glyceraldehyde-P dehydrogenase and monoamine oxidase.", "content": "Sulfhydryl reactivity of organic nitrates: biochemical basis for inhibition of glyceraldehyde-P dehydrogenase and monoamine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197820"} {"pmid": "4197822", "title": "Metabolism of 35 S-methionine and 35 S-cystine in the pregnant rhesus monkey.", "content": "Metabolism of 35 S-methionine and 35 S-cystine in the pregnant rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197822"} {"pmid": "4197824", "title": "The management of carcinoma of the breast by radical supervoltage radiation.", "content": "The management of carcinoma of the breast by radical supervoltage radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197824"} {"pmid": "4197823", "title": "Non-pulmonary surgical tuberculosis.", "content": "Non-pulmonary surgical tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197823"} {"pmid": "4197825", "title": "Chromatography of Drosophila tRNA on BD-cellulose.", "content": "Chromatography of Drosophila tRNA on BD-cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197825"} {"pmid": "4197826", "title": "The immune response to thetaX 174 in man. I. Primary and secondary antibody production in normal adults.", "content": "The immune response to thetaX 174 in man. I. Primary and secondary antibody production in normal adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197826"} {"pmid": "4197827", "title": "A comparison of in vitro, immunosuppressive and clinical effects of goat and horse anti-human thymocyte globulin in Macaca monkeys.", "content": "A comparison of in vitro, immunosuppressive and clinical effects of goat and horse anti-human thymocyte globulin in Macaca monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197827"} {"pmid": "4197829", "title": "Self-inflicted rotation osteotomy of the tibia.", "content": "Self-inflicted rotation osteotomy of the tibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197829"} {"pmid": "4197832", "title": "Stereotaxic treatment of frontal-lobe and centrencephalic epilepsy.", "content": "Stereotaxic treatment of frontal-lobe and centrencephalic epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197832"} {"pmid": "4197830", "title": "Immunoglobulin molecules on the surface of activated T lymphocytes in the rat.", "content": "Immunoglobulin molecules on the surface of activated T lymphocytes in the rat. Lewis strain rat lymphocytes were exposed in vitro to a variety of specific and nonspecific blastogenic stimuli. The surfaces of the transformed lymphocytes were examined by indirect immunofluorescence for the presence of T cell antigens and immunoglobulin molecules. More than 90% of lymphocytes that underwent blast transformation after exposure to foreign histocompatibility antigens (mixed lymphocyte reaction; in vitro allograft reaction), purified tuberculin, phytohemagglutinin (PHA), and concanavalin A (Con-A) had T cell antigenic markers on their surfaces. 70-92% of the antigen-stimulated blast cells also had readily detectable surface immunoglobulin molecules, whereas less than 3% of the PHA- and Con-A-activated cells were Ig(+). Pokeweed mitogen (PWM) appeared to activate both B and T cells, but the T cells did not have detectable surface immunoglobulin molecules. Nonactivated control cultures contained T(+)Ig(-) lymphocytes almost exclusively. The results suggest that thymus-dependent rat lymphocytes express increased amounts of detectable immunoglobulin on their surface in response to specific stimulation with antigen. It is postulated that the acquisition of immunological competence by activated T cells may be related to this expression of surface immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197830"} {"pmid": "4197833", "title": "Value of normothermic perfusion, hypothermic perfusion, and durotomy in the treatment of experimental acute spinal cord trauma.", "content": "Value of normothermic perfusion, hypothermic perfusion, and durotomy in the treatment of experimental acute spinal cord trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197833"} {"pmid": "4197831", "title": "Production of a runting syndrome and selective A deficiency in mice by the administration of anti-heavy chain antisera.", "content": "Production of a runting syndrome and selective A deficiency in mice by the administration of anti-heavy chain antisera. Conventional Swiss mice were treated from birth with intraperitoneal injections of anti-immunoglobulins in an attempt to create an experimental dysgammaglobulinemia. Mice treated with anti-gammaM were immunologically suppressed in all immunoglobulin classes as determined by serum antibody titers, splenic plaque-forming cells, serum immunoglobulin levels, and immunofluorescent analysis of plasma cells in lymphoid tissues. Treatment immediately after birth with high concentrations of anti-gammaM leads to a developmental arrest characterized by severe immunosuppression, failure to gain weight, and premature death. The pathogenesis of anti-gammaM runting syndrome is unknown. Animals similarly treated with anti-gammaG, anti-gammaA, or control normal goat or rabbit gamma-globulins developed normally. The frequency of occurrence and severity of anti-gammaM-induced runting syndrome is dependent upon the concentration of anti-gammaM-globulin administered. Administration of anti-gammaA resulted in a selective gammaA deficiency that was characterized by a marked reduction in serum-gammaA and an absence of gammaA-containing cells in the spleen. However, essentially normal numbers of plasma cells were found in the gastrointestinal lamina propria of anti-gammaA-treated animals concomitantly with suppressed levels of gammaA in intestinal fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197831"} {"pmid": "4197834", "title": "Neurophysiological assessment of afferent and efferent conduction in the injured spinal cord of monkeys.", "content": "Neurophysiological assessment of afferent and efferent conduction in the injured spinal cord of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197834"} {"pmid": "4197835", "title": "Electrical properties of toad sartorius muscle fibres in summer and winter.", "content": "Electrical properties of toad sartorius muscle fibres in summer and winter. 1. The area and circumference of surface fibres of sartorius muscles were measured from photomicrographs of frozen sections of whole muscles, and compared with the values obtained assuming a circular cross-section. The latter assumption gave an over-estimate of the mean area of 28%, but only a 2% over-estimate of the circumference. In isolated, single fibres, the assumption gave over-estimates of 25 and 6%, of area and circumference respectively.2. The passive electrical properties of fibres were different in summer and winter. The mean internal resistivity, membrane resistance and membrane capacitance were 147 Omega.cm, 7.6 kOmega.cm(2) and 4 muF/cm(2) in summer, and 194 Omega.cm, 3.9 kOmega.cm(2) and 6.7 muF/cm(2) in winter, in fibres of comparable diameters in situ. In single fibres in summer, the mean values were 120 Omega.cm, 8.6 kOmega.cm(2) and 3.6 muF/cm(2).3. In glycerol-treated fibres the mean specific membrane capacitance was 1.0 muF/cm(2) in summer and 2.0 muF/cm(2) in winter. The internal resistivity and specific membrane resistance were 167 Omega.cm and 8.9 kOmega.cm(2) in summer, and 232 Omega.cm and 3.9 kOmega.cm(2) in winter.4. Early after-depolarizations were recorded in glycerol-treated fibres which had a low membrane capacitance, did not twitch and showed little ;creep'. Electron micrographs of glycerol-treated fibres showed disruption of the transverse tubular system and sarcoplasmic reticulum.5. After exposure of muscles to 400 mM urea or acetamide for 1 hr, muscle fibres did not twitch and had a reduced membrane capacitance in Ringer solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197835"} {"pmid": "4197836", "title": "Incorporation of ethanolamine into phosphatidylethanolamine in mouse liver by exchange reaction.", "content": "Incorporation of ethanolamine into phosphatidylethanolamine in mouse liver by exchange reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197836"} {"pmid": "4197844", "title": "Progesterone-sensitive loci for blockade of ovulation in the hamster.", "content": "Progesterone-sensitive loci for blockade of ovulation in the hamster. Virgin female golden hamsters, 3-6 months old were implanted with progesterone, testosterone or cholesterol fused within the lumen of a hypodermic needle, or progesterone, cholesterol or paraffin fused into the end of a hypodermic tube or tungsten wire in order to determine progesterone-sensitive loci for blocking of ovulation. Molten steroid was drawn into 22-guage \"thin wall\", 27-guage 30-guage hypodermic tubing and then solidified. Large pellets (450 mcm) were made by dipping a 30-guage tube into molten steroid. Smaller pellets were made on the ends of tungsten wire (130 mcm). Pellets were measured on a shadowgraph to the nearest 10 mcm. The pellets were implanted through the top of the cranium and fastened with Kadon 22 dental cement. The implantation of 22-guage \"thin wall\" implants was performed 52-56 hours before ovulation and other implants 32-39 hours before the next expected ovulation. Hamsters were checked daily for ovulation by method of Orsini for 2 weeks after implantation. A hemi-ovarectomy and search for ova according to Reuter et al was performed on the day of their expected ovulation. The ovary was dissected and examined (10-30X magnification). The animals were sacrificed and brains removed, fixed in 10% formalin, serially sectioned at 100 mcm using a clinical freezing microtome, and stained with thronine to determine implantation site. Progesterone implants 18,000 sq. mcm larger resulted in blocking ovulation in the medial preoptic-diagonal band region of the hypothalamus. 28,000- 180,000 sq. mcm sizes also blocked ovulation when placed in the median eminence and in acurate nucleus regions of the hypothalamus but not in the hypophysis. The blocking effect of the hypophyseal implants can be explained by the lesion caused by the physical size of implants. Control substances did not block ovulation except when related to lesions caused by 450 mcm or 710 mcm diameter structures. Implants were effective in blocking ovulation for 2 weeks in larger implants and 1-3 days for smaller ones. The reason for this was not understood. Testosterone was also able to block ovulation in the medial preoptic-diagonal band region but to a significantly lesser degree than progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197844"} {"pmid": "4197845", "title": "Oocysts of Isospora papionis in the skeletal muscles of chacma baboons.", "content": "Oocysts of Isospora papionis in the skeletal muscles of chacma baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197845"} {"pmid": "4197846", "title": "The experimental transmission of Theileria ovis by Rhipicephalus evertsi mimeticus and R. bursa.", "content": "The experimental transmission of Theileria ovis by Rhipicephalus evertsi mimeticus and R. bursa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197846"} {"pmid": "4197847", "title": "Some protozoan parasites of tragelaphine antelopes in South Africa with special reference to a Babesia sp. in a bushbuck and a Trypanosoma Theileri-like parasite in a Nyala.", "content": "Some protozoan parasites of tragelaphine antelopes in South Africa with special reference to a Babesia sp. in a bushbuck and a Trypanosoma Theileri-like parasite in a Nyala.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197847"} {"pmid": "4197849", "title": "Mycobacteria of surgical interest.", "content": "Mycobacteria of surgical interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197849"} {"pmid": "4197850", "title": "The present status of one-stage pharyngo-esophageal diverticulectomy.", "content": "The present status of one-stage pharyngo-esophageal diverticulectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197850"} {"pmid": "4197851", "title": "Tyrosinase in melanized melanosomes.", "content": "Tyrosinase in melanized melanosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197851"} {"pmid": "4197852", "title": "The value of electrodiagnostic tests in pigmentary retinopathy.", "content": "The value of electrodiagnostic tests in pigmentary retinopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197852"} {"pmid": "4197853", "title": "Immunological responsiveness and tolerance of marmoset lymphoid tissue in vitro.", "content": "Immunological responsiveness and tolerance of marmoset lymphoid tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197853"} {"pmid": "4197854", "title": "Modification of hyperacute xenograft rejection by intra-arterial infusion of disodium ethylenediaminetetraacetate.", "content": "Modification of hyperacute xenograft rejection by intra-arterial infusion of disodium ethylenediaminetetraacetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197854"} {"pmid": "4197855", "title": "Disturbances of coagulation mechanism in protein-calorie malnutrition.", "content": "Disturbances of coagulation mechanism in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197855"} {"pmid": "4197857", "title": "Comparative histoenzymatic studies on the distribution of alkaline and acid phosphatases in the liver and pancreas of a few birds viz., Upupa epops (fam. Upupidae), Cinnyris asiatica (fam. Nectariniidae) and Halcyon smyrnensis (fam. Alcedinidae).", "content": "Comparative histoenzymatic studies on the distribution of alkaline and acid phosphatases in the liver and pancreas of a few birds viz., Upupa epops (fam. Upupidae), Cinnyris asiatica (fam. Nectariniidae) and Halcyon smyrnensis (fam. Alcedinidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197857"} {"pmid": "4197859", "title": "Lysozyme in Paneth cell secretions.", "content": "Lysozyme in Paneth cell secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197859"} {"pmid": "4197858", "title": "Linear dichroism and anomalous dispersion of the birefringence on sperm heads.", "content": "Linear dichroism and anomalous dispersion of the birefringence on sperm heads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197858"} {"pmid": "4197860", "title": "Hypokinetic effects on the RNA and protein metabolism in motoneurons of anterior horns of the rat spinal cord.", "content": "Hypokinetic effects on the RNA and protein metabolism in motoneurons of anterior horns of the rat spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197860"} {"pmid": "4197863", "title": "Polarographic investigations on Pb ++ trapping by rat liver homogenate.", "content": "Polarographic investigations on Pb ++ trapping by rat liver homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197863"} {"pmid": "4197866", "title": "Differentiation of noradrenaline and adrenaline containing cells in the adrenal medulla by the trihydroxyindole histochemical reaction.", "content": "Differentiation of noradrenaline and adrenaline containing cells in the adrenal medulla by the trihydroxyindole histochemical reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197866"} {"pmid": "4197867", "title": "Testicular leucine aminopeptidase in different vertebrates.", "content": "Testicular leucine aminopeptidase in different vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197867"} {"pmid": "4197870", "title": "Effects of alprenolol and isosorbide dinitrate in angina pectoris. A comparative study with methodological considerations.", "content": "Effects of alprenolol and isosorbide dinitrate in angina pectoris. A comparative study with methodological considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197870"} {"pmid": "4197872", "title": "A new hemodialysis console. I. General description.", "content": "A new hemodialysis console. I. General description.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197872"} {"pmid": "4197871", "title": "Changes in antithrombin 3 levels following cessation of anticoagulant therapy.", "content": "Changes in antithrombin 3 levels following cessation of anticoagulant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197871"} {"pmid": "4197873", "title": "Alprenolol alone and in conjunction with pentanitrol in angina pectoris. A double-blind study with exercise tests.", "content": "Alprenolol alone and in conjunction with pentanitrol in angina pectoris. A double-blind study with exercise tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197873"} {"pmid": "4197874", "title": "Experimental zinc chloride ocular injury and treatment with disodium edetate.", "content": "Experimental zinc chloride ocular injury and treatment with disodium edetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197874"} {"pmid": "4197875", "title": "Immunoglobulins in tears.", "content": "Immunoglobulins in tears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197875"} {"pmid": "4197877", "title": "Recovery of patients after intensive care for blunt injuries.", "content": "Recovery of patients after intensive care for blunt injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197877"} {"pmid": "4197878", "title": "Biliary excretion of 14 C-edrophonium and its glucuronide metabolite in Gunn rats.", "content": "Biliary excretion of 14 C-edrophonium and its glucuronide metabolite in Gunn rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197878"} {"pmid": "4197879", "title": "Interaction between drugs using three-dimensional isobolographic interpretation.", "content": "Interaction between drugs using three-dimensional isobolographic interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197879"} {"pmid": "4197880", "title": "Vascular reactions in the musculo-cutaneous area during the hypertension induced by acetylcholine in atropinized dogs.", "content": "Vascular reactions in the musculo-cutaneous area during the hypertension induced by acetylcholine in atropinized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197880"} {"pmid": "4197881", "title": "Pharmacological investigations with benzoctamine (Tacitin), a new psycho-active agent.", "content": "Pharmacological investigations with benzoctamine (Tacitin), a new psycho-active agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197881"} {"pmid": "4197883", "title": "The persistence of courtship stimulation in Drosophila melanogaster.", "content": "The persistence of courtship stimulation in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197883"} {"pmid": "4197882", "title": "Simple methods for plating single vegetative cells of, and for replica-plating, filamentous blue-green algae.", "content": "Simple methods for plating single vegetative cells of, and for replica-plating, filamentous blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197882"} {"pmid": "4197884", "title": "Regulation of gene function: a comparison of enzyme activity levels in relation to gene dosage in diploids and triploids of Drosophila melanogaster.", "content": "Regulation of gene function: a comparison of enzyme activity levels in relation to gene dosage in diploids and triploids of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197884"} {"pmid": "4197886", "title": "Alternative interpretation of the molecular structure and somatic genetics of acid phosphatase-1 in Tetrahymena pyriformis.", "content": "Alternative interpretation of the molecular structure and somatic genetics of acid phosphatase-1 in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197886"} {"pmid": "4197887", "title": "IgA-induced anaphylactic transfusion reactions: a report of four cases.", "content": "IgA-induced anaphylactic transfusion reactions: a report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197887"} {"pmid": "4197885", "title": "Properties of salivary basic proteins showing polymorphism.", "content": "Properties of salivary basic proteins showing polymorphism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197885"} {"pmid": "4197876", "title": "Analgetic activities of etoxadrol in the rhesus monkey and in mice.", "content": "Analgetic activities of etoxadrol in the rhesus monkey and in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197876"} {"pmid": "4197888", "title": "The invasion of burned skin by Pseudomonas aeruginosa.", "content": "The invasion of burned skin by Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197888"} {"pmid": "4197889", "title": "Haemophilus influenzae cellulitis. Case presentation and review of the literature.", "content": "Haemophilus influenzae cellulitis. Case presentation and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197889"} {"pmid": "4197890", "title": "Therapeutics XXII. Drug interaction. I.", "content": "Therapeutics XXII. Drug interaction. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197890"} {"pmid": "4197891", "title": "Immune globulin characterization of complement fixing antibodies in histoplasmic infection.", "content": "Immune globulin characterization of complement fixing antibodies in histoplasmic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197891"} {"pmid": "4197892", "title": "Left ventricular angiography as a function test.", "content": "Left ventricular angiography as a function test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197892"} {"pmid": "4197893", "title": "The Ig class and light chain type of the long acting thyroid stimulator.", "content": "The Ig class and light chain type of the long acting thyroid stimulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197893"} {"pmid": "4197894", "title": "Human chorionic somatomammotrophin and its clinical significance.", "content": "Human chorionic somatomammotrophin and its clinical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197894"} {"pmid": "4197895", "title": "Incorporation of 32 P during early amphibian embryogenesis.", "content": "Incorporation of 32 P during early amphibian embryogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197895"} {"pmid": "4197897", "title": "Combinations of the effect of radiotherapy, alkylating agents and phytohemagglutinin on sarcoma 180 in Swiss mice.", "content": "Combinations of the effect of radiotherapy, alkylating agents and phytohemagglutinin on sarcoma 180 in Swiss mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197897"} {"pmid": "4197898", "title": "Characteristics of the reverse passive respiratory reaction in Rhesus monkeys.", "content": "Characteristics of the reverse passive respiratory reaction in Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197898"} {"pmid": "4197896", "title": "The biochemical properties of esterases in Cepaea (Mollusca: Helicidae).", "content": "The biochemical properties of esterases in Cepaea (Mollusca: Helicidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197896"} {"pmid": "4197899", "title": "Characterization of an Escherichia coli mutant deficient in dihydrolipoyl dehydrogenase activity.", "content": "Characterization of an Escherichia coli mutant deficient in dihydrolipoyl dehydrogenase activity. A mutant of Escherichia coli deficient in dihydrolipoyl dehydrogenase (DHL) activity has been isolated and its characteristics have been studied. The activities of the pyruvic dehydrogenase (PDC) and alpha-ketoglutaric dehydrogenase complexes (KDC) are not present in extracts of the mutant unless purified dihydrolipoyl dehydrogenase is added. Experiments with antiserum to DHL have shown that cross-reacting material exists in mutant extracts. This suggests that the dihydrolipoyl dehydrogenase mutation (dhl(-)) is a missense structural mutation. The mutation maps very close to, if not adjacent to, the ace loci, and is not linked to the suc loci. This means the dhl locus is grouped with the genes for the other components of the PDC and not with the genes for KDC. The mutation is also transducible into prototrophic strains, demonstrating that no prior mutation is necessary for the DHL activity deficiency to exist. This evidence is consistent with the idea that there is only one gene for DHL and is supported by previous biochemical studies which have shown that DHL preparations from either enzyme complex are electrophoretically and immunochemically indistinguishable. Possible mechanisms for the genetic and metabolic control of DHL, PDC, and KDC are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197899"} {"pmid": "4197900", "title": "A bifunctional enzyme in Pseudomonas aeruginosa: a new pattern in the organization of enzymes concerned with phenylalanine and tyrosine biosynthesis.", "content": "A bifunctional enzyme in Pseudomonas aeruginosa: a new pattern in the organization of enzymes concerned with phenylalanine and tyrosine biosynthesis. Two isozymes of chorismate mutase (CA mutase(1) and CA mutase(2)) and two isozymes of prephenate dehydratase (PPA dehydratase(1) and PPA dehydratase(2)) have been found in Pseudomonas aeruginosa. The activities CA mutase(2)-PPA dehydratase(2) catalyzing phenylalanine biosynthesis have been purified almost 40-fold and were found to be associated as a bifunctional enzyme or an enzyme complex. The enzymes specific for tyrosine biosynthesis did not appear to manifest such physical association. Thus, the organization of enzymes concerned with phenylalanine and tyrosine biosynthesis in P. aeruginosa is unique and is unlike most other organisms. Single site mutants have been isolated which have lost both CA mutase(2)-PPA dehydratase(2) activities resulting in a requirement for phenylalanine for growth. Single site revertants of these mutants regained both these activities simultaneously and were able to grow on minimal medium. A mutant, r(6), was also isolated which had normal CA mutase(2) but lacked PPA dehydratase(2) activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197900"} {"pmid": "4197901", "title": "Chemical analysis of cell walls and autolytic digests of Bacillus psychrophilus.", "content": "Chemical analysis of cell walls and autolytic digests of Bacillus psychrophilus. The amino acid composition of isolated cell walls of Bacillus psychrophilus has been determined before and after extraction of protein with ethylenediamine-tetraacetic acid at 45 C. This revealed that the peptidoglycan consists of Ala, Lys, and Glu in a molar ratio of 3:1:2. By using autolytic digests of log-phase cell walls, it was possible to detect 14 ninhydrin-positive degradation products. Chemical analyses of the seven major bands from these digests indicated that the amino acid sequence of the peptide subunit in the murein of this organism consists of muramyl-l-alanyl-gamma-d-glutamyl-l-lysyl- d-alanine, and the linkage between adjacent peptides is supplied by a second d-glutamic acid which is bound to the sigma-amino group of lysine and the carboxyl group of the d-alanine through its amino group. The nature of the solubilized wall fragments indicates that each of the peptide bonds in the murein is hydrolyzed by autolysins except the l-alanyl-gamma-d-glutamyl linkage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197901"} {"pmid": "4197902", "title": "A growth initiation factor for host-independent derivatives of Bdellovibrio bacteriovorus.", "content": "A growth initiation factor for host-independent derivatives of Bdellovibrio bacteriovorus. Host-independent (H-I) derivatives of Bdellovibrio bacteriovorus 109 Davis could not be isolated when concentrated suspensions of host-dependent (H-D) cultures, washed free of spent medium, were plated on host-free media. However, H-I colonies did appear when spent broth was incorporated into the isolation medium, indicating the presence of a factor in the spent medium essential for the growth of H-I cells. This growth factor (GIF) was also present in cell-free extracts of Escherichia coli and a variety of other microorganisms including H-D and H-I derivatives of strain 109 Davis. GIF was heat stable, non-dialyzable, and present in both soluble and particulate fractions of extracts. Heating of extracts at 70 C for 10 min resulted in 10- to 40-fold stimulation in GIF activity, and evidence for a heat-labile inhibitor was obtained. Colonies appearing on host-free medium in these experiments were shown to be those of typical H-I derivatives by isolation and subsequent host-independent cultivation of these organisms. GIF was a conditional requirement dependent on age and size of inoculum for all H-I derivatives characterized. Although GIF stimulated the growth of washed exponential phase cells transferred to fresh medium, it was not essential for growth. However, it was essential for the initiation of growth of washed stationary phase cells from small inocula transferred to fresh medium. It is proposed that GIF is required to initiate growth of metabolically quiescent cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197902"} {"pmid": "4197903", "title": "Fatty acids of Myxococcus xanthus.", "content": "Fatty acids of Myxococcus xanthus. Fatty acids were extracted from saponified vegetative cells and myxospores of Myxococcus xanthus and examined as the methyl esters by gas-liquid chromatography. The acids consisted mainly of C(14) to C(17) species. Branched acids predominated, and iso-pentadecanoic acid constituted half or more of the mixture. The other leading component (11-28%) was found to be 11-n-hexadecenoic acid. Among the unsaturated acids were two diunsaturated ones, an n-hexadecadienoic acid and an iso-heptadecadienoic acid. No significant differences between the fatty acid compositions of the vegetative cells and myxospores could be detected. The fatty acid composition of M. xanthus was found to be markedly similar to that of Stigmatella aurantiaca. It is suggested that a fatty acid pattern consisting of a large proportion of iso-branched C(15) and C(17) acids and a substantial amount of an n-16:1 acid is characteristic of myxobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197903"} {"pmid": "4197904", "title": "Biological activity of heated diphtheria toxin.", "content": "Biological activity of heated diphtheria toxin. Diphtheria toxin splits into two fragments when heated at 100 C for 10 min in a phosphate buffer. The separated fragments have molecular weights of 24,000 and 39,000, respectively. These molecular weights are similar to those of the A and B fragments found in diphtheria toxin preparations after thiol reduction. Since the separation of toxin into fragments is not complete, it is likely that only nicked toxin molecules having a cleaved peptide bond are split by heating. When toxin is suspended in phosphate buffer at pH 6.4, the B-like fragment precipitates, but at pH 7.8 it does not. Heated toxin is unable to intoxicate sensitive cells or cause a necrodermal response in animals. Fragment A produced by heating is active in inhibiting cell-free protein synthesis. It is able to intoxicate both HeLa and L cells when the uptake of the fragment is facilitated by addition of polyornithine to the cultures. Fragment B produced by heating is involved with binding to the cell surface. It is able to delay the action of toxin on KB cell cultures preincubated with fragment B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197904"} {"pmid": "4197906", "title": "Scanning electron microscopy of colonies of six species of Candida.", "content": "Scanning electron microscopy of colonies of six species of Candida. Thirty strains of six species of Candida isolated from patients were cultured for 60 h on Sabouraud agar, freeze-dried, and examined with a scanning electron microscope. The colonies were circular (Candida albicans, C. guilliermondii) or oval (C. tropicalis, C. pseudotropicalis, C. krusei, C. parakrusei) in outline, and those of C. pseudotropicalis and C. krusei had an irregular outline due to a peripheral pseudomycelium. The morphology of individual microorganisms was examined at the margins and apex of those species which lacked a surface coat (C. pseudotropicalis, C. krusei, C. parakrusei, C. guilliermondii), and through cracks in the surface coating of those which showed a surface coat (C. albicans, C. tropicalis). All species showed buds, bud scars, and interconnecting intercellular processes, but were generally spherical (C. albicans, C. tropicalis) or ovoid (C. pseudotropicalis, C. krusei, C. parakrusei, C. guilliermondii) in fixed preparations. In unfixed material, individual organisms were almost invariably indented. Fixation with 3% glutaraldehyde and washing before freeze-drying caused partial removal of the surface coating of colonies of C. albicans and C. tropicalis, which persisted only as irregular sheets or as a filamentous meshwork. This filamentous meshwork was also present among the organisms of colonies of C. albicans, C. tropicalis, and C. pseudotropicalis. It is concluded that these filaments represent the precipitation or unmasking of some component of the intercellular matrix of these organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197906"} {"pmid": "4197905", "title": "Cell surface protein of Pseudomonas (Hydrogenomonas) facilis.", "content": "Cell surface protein of Pseudomonas (Hydrogenomonas) facilis. Intact cells of Pseudomonas facilis contain one major molecular weight class of protein that is exposed at the cell surface as revealed by lactoperoxidase-catalyzed iodination with (125)I. All molecular weight classes of protein in derived cell envelope preparations are apparently saturated by iodination by lactoperoxidase after prolonged sonic treatment. The molecular weight of the predominantly exposed protein in intact cells is approximately 16,000, which is the minimal molecular weight of a cell envelope protein that precipitates as a complex with phospholipid from extracts of P. facilis. The isolation of labeled phospholipoprotein (PLP) after labeling intact cells with (125)I corroborates previous experiments which suggested a surface location for the protein portion of the phospholipoprotein (P(PLP)). Solvent extraction of cells and immunological evidence, including studies with ferritin-coupled antibodies, indicate that P(PLP) is located at the cell surface and may also be within the cell envelope. These experiments suggest that P(PLP) is the major cell surface protein in P. facilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197905"} {"pmid": "4197907", "title": "Purification of Synechococcus lividus by equilibrium centrifugation and its synchronization by differential centrifugation.", "content": "Purification of Synechococcus lividus by equilibrium centrifugation and its synchronization by differential centrifugation. A culture of the thermophilic, unicellular, blue-green alga Synechococcus lividus was freed from two thermophilic bacteria by use of equilibrium (isopycnic) centrifugation in Ficoll density gradients. After removal of the bacteria, the alga would grow only on agar plates in a high carbon dioxide atmosphere. Intermittent illumination, equilibrium centrifugation, and differential centrifugation were tested as techniques for obtaining synchronized cultures of the alga. Daughter cells selected by differential centrifugation in Ficoll density gradients yielded the best synchrony, and a cross-wall index of 85% was observed during the period of cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197907"} {"pmid": "4197908", "title": "Loss of photosynthetic activity in two blue-green algae as a result of osmotic stress.", "content": "Loss of photosynthetic activity in two blue-green algae as a result of osmotic stress. A progressive loss of photosynthetic activity occurred when cells of Anacystis nidulans and Coccochloris peniocystis were incubated in increasing concentrations of osmotica from 0.2 to 0.7 M, and there was a release of pteridine from the cells proportional to the loss of photosynthetic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197908"} {"pmid": "4197909", "title": "Agglutination of bacterial spheroplasts: agglutination-dependent degradation of Escherichia coli ribosomal ribonucleic acid.", "content": "Agglutination of bacterial spheroplasts: agglutination-dependent degradation of Escherichia coli ribosomal ribonucleic acid. When Escherichia coli spheroplasts made by ethylenediaminetetraacetic acid and lysozyme were agglutinated by concanavalin A (con A), the degradation of ribosomal ribonucleic acid (rRNA) was found to occur proportionally to the degree of the agglutination, which was determined by microscopic examination or by a newly devised assay based on the slower settling of aggregates. Methyl-alpha-d-glucoside, low temperature or alkaline pH, all of which reverse the agglutination, also reduced the extent of rRNA degradation. This degradation was not due to the direct action of con A since a similar relationship was found in the case of spontaneous agglutination with concentrated spheroplasts in the absence of con A. The possible importance of a change in the cell membrane associated with the agglutination process is discussed in connection with the initiation of rRNA degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197909"} {"pmid": "4197910", "title": "Fatty acid composition of L-forms of Streptococcus faecalis cultured at different osmolalities.", "content": "Fatty acid composition of L-forms of Streptococcus faecalis cultured at different osmolalities. The fatty acid composition of the membranes of three different penicillin-produced L-forms of Streptococcus faecalis was determined: (i) a stable (nonreverting) L-form (T(53)) cultured in brain heart infusion (BHI) with 0.5 M sucrose; (ii) a stable L-form (T(531)) cultured in BHI without sucrose; and (iii) an unstable L-form (T(9)) cultured in BHI with 0.5 M sucrose and 1,000 U of penicillin per ml. L-forms were obtained by centrifugation and lysed by washing in 1 mM tris(hydroxymethyl)aminomethane-hydrochloride buffer. The parent S. faecalis was also cultured in BHI and BHI containing 0.5 M sucrose, and washed with buffer. The fatty acid composition of L-forms of S. faecalis cultured in BHI without sucrose (370 mosmol) had higher C(18:1) and lower C(18) than L-forms cultured in the same media with added 0.5 M sucrose (950 mosmol) in both exponential and stationary cultures. In the stationary phase of growth, C(19) was reduced in the L-forms cultured without sucrose. Similar changes were seen in the parent S. faecalis cultured in the two types of media. These changes in membrane fatty acids may relate to osmo-regulation of the L-forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197910"} {"pmid": "4197912", "title": "Dissociated learning and state-dependent retention induced by pentobarbital in rhesus monkeys.", "content": "Dissociated learning and state-dependent retention induced by pentobarbital in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197912"} {"pmid": "4197911", "title": "Detergent-dispersed adenylate cyclase from rat brain. Effects of fluoride, cations, and chelators.", "content": "Detergent-dispersed adenylate cyclase from rat brain. Effects of fluoride, cations, and chelators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197911"} {"pmid": "4197913", "title": "Glucosamine HCl, hydroxyproline and developmental homoeostasis in Drosophila melanogaster.", "content": "Glucosamine HCl, hydroxyproline and developmental homoeostasis in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197913"} {"pmid": "4197914", "title": "H. influenzae pneumonia in infants and children.", "content": "H. influenzae pneumonia in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197914"} {"pmid": "4197915", "title": "Insulin and sodium bicarbonate treatment of diabetic acidosis: a retrospective review.", "content": "Insulin and sodium bicarbonate treatment of diabetic acidosis: a retrospective review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197915"} {"pmid": "4197916", "title": "Cromolyn therapy for severe asthma in children.", "content": "Cromolyn therapy for severe asthma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197916"} {"pmid": "4197917", "title": "Blood lipid alterations in infants receiving intravenous fat-free alimentation.", "content": "Blood lipid alterations in infants receiving intravenous fat-free alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197917"} {"pmid": "4197918", "title": "Postexchange transfusion hepatitis in the newborn infant.", "content": "Postexchange transfusion hepatitis in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197918"} {"pmid": "4197920", "title": "Physiotherapy and the care of the progressively ill patient. 2. The unconscious and bed-ridden patient.", "content": "Physiotherapy and the care of the progressively ill patient. 2. The unconscious and bed-ridden patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197920"} {"pmid": "4197921", "title": "Serological titres following vaccination of sheep and goats with Brucella melitensis rev I vaccine.", "content": "Serological titres following vaccination of sheep and goats with Brucella melitensis rev I vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197921"} {"pmid": "4197922", "title": "A serological investigation on adult cattle vaccinated with Brucella abortus strain 19.", "content": "A serological investigation on adult cattle vaccinated with Brucella abortus strain 19.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197922"} {"pmid": "4197924", "title": "Prostaglandins and food intake of rats: a component of energy balance regulation?", "content": "Prostaglandins and food intake of rats: a component of energy balance regulation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197924"} {"pmid": "4197923", "title": "Hyperphagia induced by intrahypothalamic implants of mercury thioglucose.", "content": "Hyperphagia induced by intrahypothalamic implants of mercury thioglucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197923"} {"pmid": "4197919", "title": "Diabetes and pregnancy.", "content": "Diabetes and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197919"} {"pmid": "4197925", "title": "A simple method for measuring spontaneous motor activity in squirrel monkeys during chair restraint.", "content": "A simple method for measuring spontaneous motor activity in squirrel monkeys during chair restraint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197925"} {"pmid": "4197927", "title": "Neurophysiology of flight in wild-type and a mutant Drosophila.", "content": "Neurophysiology of flight in wild-type and a mutant Drosophila. We report the flight motor output pattern in Drosophila melanogaster and the neural network responsible for it, and describe the bursting motor output pattern in a mutant. There are 26 singly-innervated muscle fibers. There are two basic firing patterns: phase progression, shown by units that receive a common input but have no cross-connections, and phase stability, in which synergic units, receiving a common input and inhibiting each other, fire in a repeating sequence. Flies carrying the mutation stripe cannot fly. Their motor output is reduced to a short duration, high-frequency burst, but the patterning within bursts shows many of the characteristics of the wild type. The mutation is restricted in its effect, as the nervous system has normal morphology by light microscopy and other behaviors of the mutant are normal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197927"} {"pmid": "4197926", "title": "Effect of hemin on the synthesis of hemoglobin and other proteins in mammalian cells.", "content": "Effect of hemin on the synthesis of hemoglobin and other proteins in mammalian cells. The initiation of globin synthesis in intact reticulocytes and in reticulocyte lysates is maintained by the addition of hemin. The specificity of this effect has been studied to determine whether it is restricted to hemoglobin and erythroid cells. In intact reticulocytes, hemin (500 muM) enhances the synthesis of carbonic anhydrase as well as of hemoglobin. Similar enhancement of protein synthesis is observed on addition of hemin (500 muM) to intact Krebs II ascites tumor cells, in cell-free extracts of these cells, added hemin (50 muM) increases endogenous protein synthesis and the translation of exogenous rabbit globin messenger RNA. These results provide evidence that the effect of hemin is not restricted to globin, and they suggest that hemin may enhance protein synthesis in at least some nonerythroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197926"} {"pmid": "4197928", "title": "Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent.", "content": "Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent. The antiviral activity of the synthetic nucleoside, Virazole (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide), against measles virus in Vero cell cultures was substantially reversed by xanthosine, guanosine, and to a slightly lesser extent by inosine. Virazole 5'-phosphate was subsequently found to be a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase (IMP:NAD(+) oxidoreductase, EC 1.2.1.14) isolated from Escherichia coli (K(m) = 1.8 x 10(-5) M) with a K(i) of 2.7 x 10(-7) M. Guanosine 5'-phosphate (GMP) was a competitive inhibitor of this enzyme with a K(i) of 7.7 x 10(-5) M. Virazole 5'-phosphate was similarly active against IMP dehydrogenase isolated from Ehrlich ascites tumor cells, with a K(i) of 2.5 x 10(-7) M. The K(m) for this enzyme was 1.8 x 10(-5) M, and the K(i) for GMP was 2.2 x 10(-4) M. These results suggest that the antiviral activity of Virazole might be due to the inhibition of GMP biosynthesis in the infected cell at the step involving the conversion of IMP to xanthosine 5'-phosphate. This inhibition would consequently result in inhibition of the synthesis of vital viral nucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197928"} {"pmid": "4197929", "title": "An RNA polymerase mutation causing temperature-sensitive sporulation in Bacillus subtilis.", "content": "An RNA polymerase mutation causing temperature-sensitive sporulation in Bacillus subtilis. A single-site mutant of Bacillus subtilis with a rifampin-resistant RNA polymerase has been isolated; this mutation causes temperature-sensitive sporulation. The temperature-sensitive mutation was only expressed during a limited time period, covering the middle third of the sporulation sequence. Mutant cells grown at the nonpermissive temperature exhibited the normal change in RNA polymerase template specificity, accumulated extracellular proteolytic activity and antibiotic activity, but failed to accumulate alkaline phosphatase and, hence, were blocked at or near stage III in the sporulation sequence. Pulse-labeled RNA synthesis was seriously deranged during postexponential growth phase in mutant cells incubated at the nonpermissive temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197929"} {"pmid": "4197931", "title": "Magnetic dipole-dipole coupled Cu(II) pairs in nitric oxide-treated tyrosinase: a structural relationship between the active sites of tyrosinase and hemocyanin.", "content": "Magnetic dipole-dipole coupled Cu(II) pairs in nitric oxide-treated tyrosinase: a structural relationship between the active sites of tyrosinase and hemocyanin. The T(r) and T[unk] states of tyrosinase were treated with NO. EPR spectra of the products observed at 14 degrees K and at 113 degrees K showed mixtures of two signals. One had components in the region of g = 2, about 1200 G wide, and in the region of g = 4, showing hyperfine splitting. The other signal was similar to that arising from isolated Cu(II) ions in an axially symmetric environment. The first signal was indicative of Deltam = 1 and Deltam = 2 transitions arising from magnetic dipole-dipole coupled Cu(II) ion pairs. It closely resembled previously reported EPR spectra obtained from NO-treated hemocyanin, which were confirmed in this study. The normal Curie behavior of the signals between 230 degrees K and 14 degrees K ruled out significant exchange coupling between the ion pairs. The Deltam = 2 signals were not saturable up to 350 mW at 14 degrees K. The broad Deltam = 1 signals could be separated from accompanying signals by the saturation characteristics of the latter at about 10 mW at 14 degrees K. The results establish the presence of a pair of copper ions at the active site of tyrosinase, and a clsoe structural relationship between this active site and that of hemocyanin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197931"} {"pmid": "4197930", "title": "Inhibition of cellular protein synthesis by double-stranded RNA: inactivation of an initiation factor.", "content": "Inhibition of cellular protein synthesis by double-stranded RNA: inactivation of an initiation factor. Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA is caused by the inactivation of IF-3, an initiation factor required for the recycling of ribosomes and for their binding to messenger RNA. The evidence for this is that (i) the inhibition can be overcome by addition of exogenous If-3; (ii) double-stranded RNA inactivates stoichiometric amounts of IF-3; (iii) double-stranded RNA forms a complex with IF-3; and (iv) double-stranded DNA, which lacks inhibitory activity, also binds to IF-3, but with a much lower affinity than double-stranded RNA. It is concluded that double-stranded RNA inhibits cellular protein synthesis by tightly complexing with IF-3. It is suggested that IF-3 normally recognizes a double-stranded region in messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197930"} {"pmid": "4197932", "title": "Epilepsy after non-missile head injuries.", "content": "Epilepsy after non-missile head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197932"} {"pmid": "4197933", "title": "Stroma-free hemoglobin. I. Preparation and observations on in vitro changes in coagulation.", "content": "Stroma-free hemoglobin. I. Preparation and observations on in vitro changes in coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197933"} {"pmid": "4197934", "title": "Altered insulin and glucose metabolism produced by epinephrine during hemorrhagic shock in the adrenalectomized primate.", "content": "Altered insulin and glucose metabolism produced by epinephrine during hemorrhagic shock in the adrenalectomized primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197934"} {"pmid": "4197935", "title": "The effect of hemorrhagic shock on intracellular muscle action potentials in the primate.", "content": "The effect of hemorrhagic shock on intracellular muscle action potentials in the primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197935"} {"pmid": "4197941", "title": "A brief note on the chemical nature of the precipitate within nerve fibers after the rapid Golgi reaction: selected area diffraction in high voltage electron microscopy.", "content": "A brief note on the chemical nature of the precipitate within nerve fibers after the rapid Golgi reaction: selected area diffraction in high voltage electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197941"} {"pmid": "4197942", "title": "Architectonic parcellation of the temporal operculum in rhesus monkey and its projection pattern.", "content": "Architectonic parcellation of the temporal operculum in rhesus monkey and its projection pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197942"} {"pmid": "4197945", "title": "-aminolaevulinic acid synthetase activity in normal human liver homogenate.", "content": "-aminolaevulinic acid synthetase activity in normal human liver homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197945"} {"pmid": "4197946", "title": "Factors influencing splenic pooling of erythrocytes in the myelo- and lympho-proliferative syndromes.", "content": "Factors influencing splenic pooling of erythrocytes in the myelo- and lympho-proliferative syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197946"} {"pmid": "4197947", "title": "Serum B 12 binders in vitamin B 12 deficiency. Relation of serum B 12 and haemoglobin levels with B 12 binders.", "content": "Serum B 12 binders in vitamin B 12 deficiency. Relation of serum B 12 and haemoglobin levels with B 12 binders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197947"} {"pmid": "4197948", "title": "Effect of corticosteroids on eosinophil leukocytes in hypereosinophilic syndromes.", "content": "Effect of corticosteroids on eosinophil leukocytes in hypereosinophilic syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197948"} {"pmid": "4197949", "title": "Haematological effects of chronic ethanol administration and folic acid deficiency in mice.", "content": "Haematological effects of chronic ethanol administration and folic acid deficiency in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197949"} {"pmid": "4197950", "title": "Adult human adipose tissue cellularity and metabolism with special reference to obesity and fatty acid synthesis de novo.", "content": "Adult human adipose tissue cellularity and metabolism with special reference to obesity and fatty acid synthesis de novo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197950"} {"pmid": "4197951", "title": "Calciun-sensitive site in the carotid trunk at the thyroid artery issue, influencing the respiratory centre.", "content": "Calciun-sensitive site in the carotid trunk at the thyroid artery issue, influencing the respiratory centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197951"} {"pmid": "4197952", "title": "Tumor-like lesion of the brain caused by Trypanosoma cruzi.", "content": "Tumor-like lesion of the brain caused by Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197952"} {"pmid": "4197953", "title": "Some epidemiological considerations of scrub typhus (Rickettsia tsutsugamushi) in a natural focus in the Zambales Mountains, Luzon, Republic of the Philippines.", "content": "Some epidemiological considerations of scrub typhus (Rickettsia tsutsugamushi) in a natural focus in the Zambales Mountains, Luzon, Republic of the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197953"} {"pmid": "4197954", "title": "Annually recurrent epidemic polyarthritis and Ross river virus activity in a coastal area of new New South Wales. I. Occurrence of the disease.", "content": "Annually recurrent epidemic polyarthritis and Ross river virus activity in a coastal area of new New South Wales. I. Occurrence of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197954"} {"pmid": "4197955", "title": "Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma.", "content": "Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197955"} {"pmid": "4197956", "title": "Systemic factors and epileptic brain damage. Prolonged seizures in paralyzed, artificially ventilated baboons.", "content": "Systemic factors and epileptic brain damage. Prolonged seizures in paralyzed, artificially ventilated baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197956"} {"pmid": "4197957", "title": "Size dependent separation of high molecular weight double-stranded DNA by means of gel electrophoresis.", "content": "Size dependent separation of high molecular weight double-stranded DNA by means of gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197957"} {"pmid": "4197958", "title": "Dynamic aspects of membrane-bound DNA in Bacillus subtilis during the course of synchronous growth.", "content": "Dynamic aspects of membrane-bound DNA in Bacillus subtilis during the course of synchronous growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197958"} {"pmid": "4197959", "title": "Amino acid sequence of human erythrocyte carbonic anhydrase C.", "content": "Amino acid sequence of human erythrocyte carbonic anhydrase C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197959"} {"pmid": "4197961", "title": "Induction of biohydrogenation of oleic acid in Bacillus cereus by increase in temperature.", "content": "Induction of biohydrogenation of oleic acid in Bacillus cereus by increase in temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197961"} {"pmid": "4197960", "title": "Energy-linked swelling of EDTA submitochondrial particles.", "content": "Energy-linked swelling of EDTA submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197960"} {"pmid": "4197962", "title": "Molecular organization in bacterial cell membranes. II. Reevaluation and identification of some chemical components of Micrococcus lysodeikticus membranes.", "content": "Molecular organization in bacterial cell membranes. II. Reevaluation and identification of some chemical components of Micrococcus lysodeikticus membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197962"} {"pmid": "4197963", "title": "Euglycemic diabetic ketoacidosis.", "content": "Euglycemic diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197963"} {"pmid": "4197964", "title": "Monkeys for research.", "content": "Monkeys for research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197964"} {"pmid": "4197969", "title": "Morphological observations on the contact-induced lysis of target cells.", "content": "Morphological observations on the contact-induced lysis of target cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197969"} {"pmid": "4197970", "title": "Macrophage cytotoxicity factor. A product of in vitro sensitized thymus-dependent cells.", "content": "Macrophage cytotoxicity factor. A product of in vitro sensitized thymus-dependent cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197970"} {"pmid": "4197968", "title": "Circulating immune complexes in inflammatory bowel disease.", "content": "Circulating immune complexes in inflammatory bowel disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197968"} {"pmid": "4197971", "title": "Rosette formation by human T and B lymphocytes.", "content": "Rosette formation by human T and B lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197971"} {"pmid": "4197972", "title": "Plasmodium berghei: folic acid levels in mouse erythrocytes.", "content": "Plasmodium berghei: folic acid levels in mouse erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197972"} {"pmid": "4197973", "title": "Plasmodium falciparum and P. knowlesi: low temperature preservation using dimethylsulfoxide.", "content": "Plasmodium falciparum and P. knowlesi: low temperature preservation using dimethylsulfoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197973"} {"pmid": "4197974", "title": "Studies in myasthenia gravis. Heat stability and species specificity of active muscle antigens.", "content": "Studies in myasthenia gravis. Heat stability and species specificity of active muscle antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197974"} {"pmid": "4197976", "title": "Scoliosis and neurological disease.", "content": "Scoliosis and neurological disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197976"} {"pmid": "4197975", "title": "Role of anaerobic coryneforms in specific and non-specific immunological reactions. II. Production of a chemotactic factor specific for macrophages.", "content": "Role of anaerobic coryneforms in specific and non-specific immunological reactions. II. Production of a chemotactic factor specific for macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197975"} {"pmid": "4197978", "title": "A direct turbidimetric assay of pyocine.", "content": "A direct turbidimetric assay of pyocine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197978"} {"pmid": "4197977", "title": "Cross reactions between the antigen of human lymphatic tissues and antigens of monkey, cow, mouse and hamster tissues.", "content": "Cross reactions between the antigen of human lymphatic tissues and antigens of monkey, cow, mouse and hamster tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197977"} {"pmid": "4197980", "title": "Some aspects of the mode of action of the antibacterial compound bronopol (2-bromo-2-nitropropan-1,3-diol).", "content": "Some aspects of the mode of action of the antibacterial compound bronopol (2-bromo-2-nitropropan-1,3-diol).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197980"} {"pmid": "4197979", "title": "The influence of sporulation and germination media on the development of spores of Bacillus megaterium and their inhibition by chlorocresol.", "content": "The influence of sporulation and germination media on the development of spores of Bacillus megaterium and their inhibition by chlorocresol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197979"} {"pmid": "4197981", "title": "Immunochemical analysis of chick phosvitin.", "content": "Immunochemical analysis of chick phosvitin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197981"} {"pmid": "4197982", "title": "Pulmonary host defenses. I. Analysis of protein and lipids in bronchial secretions and antibody responses after vaccination with pseudomonas aeruginosa.", "content": "Pulmonary host defenses. I. Analysis of protein and lipids in bronchial secretions and antibody responses after vaccination with pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197982"} {"pmid": "4197984", "title": "Protection against enteric bacterial infection by secretory IgA antibodies.", "content": "Protection against enteric bacterial infection by secretory IgA antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197984"} {"pmid": "4197983", "title": "Pulmonary host defenses. II. Interaction of respiratory antibodies with Pseudomonas aeruginosa and alveolar macrophages.", "content": "Pulmonary host defenses. II. Interaction of respiratory antibodies with Pseudomonas aeruginosa and alveolar macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197983"} {"pmid": "4197985", "title": "Immunologic studies on drug addiction. I. Antibodies reactive with methadone and their use for detection of the drug.", "content": "Immunologic studies on drug addiction. I. Antibodies reactive with methadone and their use for detection of the drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197985"} {"pmid": "4197986", "title": "A latex agglutination test for measuring antibodies to Streptococcal mucopeptides.", "content": "A latex agglutination test for measuring antibodies to Streptococcal mucopeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197986"} {"pmid": "4197987", "title": "Application of electroimmunodiffusion and crossed electroimmunodiffusion to the comparative serology of a microorganism (Histoplasma capsulatum).", "content": "Application of electroimmunodiffusion and crossed electroimmunodiffusion to the comparative serology of a microorganism (Histoplasma capsulatum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197987"} {"pmid": "4197988", "title": "Immunogenicity and arthritogenicity in the rat of an antigen from Mycobacterium tuberculosis wax D.", "content": "Immunogenicity and arthritogenicity in the rat of an antigen from Mycobacterium tuberculosis wax D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197988"} {"pmid": "4197989", "title": "Radioimmunologic measurements of naturally occurring bacterial antibodies. I. Human serum antibodies reactive with Escherichia coli in gastrointestinal and immunologic disorders.", "content": "Radioimmunologic measurements of naturally occurring bacterial antibodies. I. Human serum antibodies reactive with Escherichia coli in gastrointestinal and immunologic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197989"} {"pmid": "4197991", "title": "IgG, IgA, and IgM cold-reactive immunoglobulins in 19 patients with elevated cold agglutinins.", "content": "IgG, IgA, and IgM cold-reactive immunoglobulins in 19 patients with elevated cold agglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197991"} {"pmid": "4197992", "title": "Lymphocyte function in normal people with persistent Australia antigen.", "content": "Lymphocyte function in normal people with persistent Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197992"} {"pmid": "4197990", "title": "Measurement of the third component of complement in cerebrospinal fluid by modified electroimmunodiffusion.", "content": "Measurement of the third component of complement in cerebrospinal fluid by modified electroimmunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197990"} {"pmid": "4197993", "title": "Isolated in vivo perfusion of the baboon brain with uncomplicated survival: a new experimental model.", "content": "Isolated in vivo perfusion of the baboon brain with uncomplicated survival: a new experimental model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197993"} {"pmid": "4197994", "title": "Cisternography: from early tribulations to a useful diagnostic procedure.", "content": "Cisternography: from early tribulations to a useful diagnostic procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197994"} {"pmid": "4197996", "title": "An automated method for microbiological assays.", "content": "An automated method for microbiological assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197996"} {"pmid": "4197997", "title": "Observations on Listeria monocytogenes type 5 (Iwanow) isolated in New Zealand.", "content": "Observations on Listeria monocytogenes type 5 (Iwanow) isolated in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197997"} {"pmid": "4198000", "title": "Three new fragments, F(ab) 2 , F(c) 2 , and Fab-c, obtained by papain proteolysis of normal human IgG.", "content": "Three new fragments, F(ab) 2 , F(c) 2 , and Fab-c, obtained by papain proteolysis of normal human IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198000"} {"pmid": "4198001", "title": "Lectins in precipitin reactions with soluble H substance of human saliva and serum.", "content": "Lectins in precipitin reactions with soluble H substance of human saliva and serum. Lectins that precipitate the soluble H substances of saliva were produced for the first time from the four commonly used sources of seed. In Ouchterlony precipitin reactions, identity was observed between extracts of Cytisus sessilifolius and Laburnum alpinum, but these extracts displayed incomplete identity with extracts from Ulex europaeus. These three sources of the precipitating lectin formed bands when tested with saliva from all secretors and none with saliva from nonsecretors. Extracts from Lotus tetragonolobus, however, formed two bands with saliva from secretors and one strong band with all saliva from nonsecretors. This new antigen, which reacts with Lotus, is present in all saliva and on red cells of all normal individuals, but it is absent in the O(h) (Bombay) type. The lectins formed bands with serums of secretor and nonsecretor individuals, but these bands were weaker than those with saliva, and revealed incomplete identity between H substance of serum and saliva. The precipitin reaction of the lectins is an efficient method for demonstrating relations among lectins and among antigens and has led to the discovery of a new human antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198001"} {"pmid": "4198002", "title": "The picornaviruses of epidemic conjunctivitis.", "content": "The picornaviruses of epidemic conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198002"} {"pmid": "4198003", "title": "Coagulation and fibrinolysis in simian Plasmodium knowlesi malaria.", "content": "Coagulation and fibrinolysis in simian Plasmodium knowlesi malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198003"} {"pmid": "4198004", "title": "Studies on the phagocytic activity of the reticuloendothelial system using 131 I-AA in normal monkeys.", "content": "Studies on the phagocytic activity of the reticuloendothelial system using 131 I-AA in normal monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198004"} {"pmid": "4197995", "title": "The mode of action of Sterinol on microorganisms: effect on the external layers of bacterial cells.", "content": "The mode of action of Sterinol on microorganisms: effect on the external layers of bacterial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4197995"} {"pmid": "4198009", "title": "The morphology of the juxtaglomerular apparatus in the toad, Bufo bufo. A light microscopic study.", "content": "The morphology of the juxtaglomerular apparatus in the toad, Bufo bufo. A light microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198009"} {"pmid": "4198010", "title": "Perforation of a jejunal diverticulum containing a lymphosarcoma and accompanied by upper gastrointestinal hemorrhage. Report of a case.", "content": "Perforation of a jejunal diverticulum containing a lymphosarcoma and accompanied by upper gastrointestinal hemorrhage. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198010"} {"pmid": "4198008", "title": "Early stages of synaptogenesis in the cervical spinal cord of the chick embryo.", "content": "Early stages of synaptogenesis in the cervical spinal cord of the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198008"} {"pmid": "4198011", "title": "A survey of 99 surgical patients treated with gentamycin.", "content": "A survey of 99 surgical patients treated with gentamycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198011"} {"pmid": "4198013", "title": "Foamy virus serotypes 1 and 2 in rhesus monkey tissues.", "content": "Foamy virus serotypes 1 and 2 in rhesus monkey tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198013"} {"pmid": "4198014", "title": "Bovine ephemeral fever virus in cell culture and mice.", "content": "Bovine ephemeral fever virus in cell culture and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198014"} {"pmid": "4198016", "title": "Factors affecting the response of microsomal UDP-glucuronyltransferase to membrane perturbants.", "content": "Factors affecting the response of microsomal UDP-glucuronyltransferase to membrane perturbants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198016"} {"pmid": "4198015", "title": "Gold nephropathy. An immunopathologic study.", "content": "Gold nephropathy. An immunopathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198015"} {"pmid": "4198018", "title": "On the nature of the mid-oseophageal diverticulum.", "content": "On the nature of the mid-oseophageal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198018"} {"pmid": "4198017", "title": "Characteristics of H + and NH 4 + excretion by the urinary bladder of the toad.", "content": "Characteristics of H + and NH 4 + excretion by the urinary bladder of the toad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198017"} {"pmid": "4198020", "title": "Non-autonomy of hormone secretion in primary hyperparathyroidism.", "content": "Non-autonomy of hormone secretion in primary hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198020"} {"pmid": "4198021", "title": "Neoplastic changes in the rat liver induced by polychlorinated biphenyl.", "content": "Neoplastic changes in the rat liver induced by polychlorinated biphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198021"} {"pmid": "4198022", "title": "Carriers of hepatitis B antigen: an epidemiologic and histologic study.", "content": "Carriers of hepatitis B antigen: an epidemiologic and histologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198022"} {"pmid": "4198023", "title": "Evaluation of the vaginal tampon as a means of obtaining cultures for Neisseria gonorrhoeae.", "content": "Evaluation of the vaginal tampon as a means of obtaining cultures for Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198023"} {"pmid": "4198024", "title": "Studies on the pathogenesis of dengue infection in monkeys. II. Clinical laboratory responses to heterologous infection.", "content": "Studies on the pathogenesis of dengue infection in monkeys. II. Clinical laboratory responses to heterologous infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198024"} {"pmid": "4198025", "title": "Studies on the pathogenesis of dengue infection in monkeys. 3. Sequential distribution of virus in primary and heterologous infections.", "content": "Studies on the pathogenesis of dengue infection in monkeys. 3. Sequential distribution of virus in primary and heterologous infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198025"} {"pmid": "4198026", "title": "Antigenicity of a polysaccharide vaccine from Neisseria meningitidis administered intranasally.", "content": "Antigenicity of a polysaccharide vaccine from Neisseria meningitidis administered intranasally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198026"} {"pmid": "4198027", "title": "Studies on the pathogenesis of dengue infection in monkeys. I. Clinical laboratory responses to primary infection.", "content": "Studies on the pathogenesis of dengue infection in monkeys. I. Clinical laboratory responses to primary infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198027"} {"pmid": "4198028", "title": "Potent anti-inflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-dioxide.", "content": "Potent anti-inflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198028"} {"pmid": "4198029", "title": "Nitrones. 6. -(5-Nitroimidazol-2-yl)-N-substituted nitrones.", "content": "Nitrones. 6. -(5-Nitroimidazol-2-yl)-N-substituted nitrones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198029"} {"pmid": "4198030", "title": "Selection of a fast-growing Chikungunya virus by passage from suckling mouse brain to VERO cells.", "content": "Selection of a fast-growing Chikungunya virus by passage from suckling mouse brain to VERO cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198030"} {"pmid": "4198032", "title": "Contamination of methylmethacrylate bone cements.", "content": "Contamination of methylmethacrylate bone cements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198032"} {"pmid": "4198033", "title": "The use of a balloon catheter in the induction of labour.", "content": "The use of a balloon catheter in the induction of labour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198033"} {"pmid": "4198034", "title": "Diseases of the alimentary tract and western diets.", "content": "Diseases of the alimentary tract and western diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198034"} {"pmid": "4198041", "title": "Oculomotor deficiency after cerebellar cortical lesions.", "content": "Oculomotor deficiency after cerebellar cortical lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198041"} {"pmid": "4198031", "title": "Toxicogenic potentials of biomaterials and methods for evaluating toxicity.", "content": "Toxicogenic potentials of biomaterials and methods for evaluating toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198031"} {"pmid": "4198040", "title": "Structure and connections of the rhesus vestibular cortex.", "content": "Structure and connections of the rhesus vestibular cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198040"} {"pmid": "4198042", "title": "Ultrastructure of the otolithic membrane and the cupula. A scanning electron microscopic observation.", "content": "Ultrastructure of the otolithic membrane and the cupula. A scanning electron microscopic observation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198042"} {"pmid": "4198043", "title": "Prebiotic evolution of enzyme-like systems.", "content": "Prebiotic evolution of enzyme-like systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198043"} {"pmid": "4198044", "title": "Netherlands Society for Microbiology meeting at Delft on 25 October 1972. Mycotoxins.", "content": "Netherlands Society for Microbiology meeting at Delft on 25 October 1972. Mycotoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198044"} {"pmid": "4198047", "title": "The ultrastructure of the blood vessels of the human dental pulp following injury. IV.", "content": "The ultrastructure of the blood vessels of the human dental pulp following injury. IV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198047"} {"pmid": "4198048", "title": "Serum immunoglobulin conten in normal and lymphoid tumor-bearing Xenopus laevis.", "content": "Serum immunoglobulin conten in normal and lymphoid tumor-bearing Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198048"} {"pmid": "4198049", "title": "The frequency of other handicaps in children with cerebral palsy.", "content": "The frequency of other handicaps in children with cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198049"} {"pmid": "4198050", "title": "The influence of antibovine alpha-crystallin on the development of the rabbit eye.", "content": "The influence of antibovine alpha-crystallin on the development of the rabbit eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198050"} {"pmid": "4198051", "title": "Integumental distribution of tyrosinase activity in the slow loris, Nycticebus coucang, and the presence of integumental tyrosinase inhibitor(s).", "content": "Integumental distribution of tyrosinase activity in the slow loris, Nycticebus coucang, and the presence of integumental tyrosinase inhibitor(s).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198051"} {"pmid": "4198053", "title": "The topography of the premaxillary-frontal region in nonhuman primates.", "content": "The topography of the premaxillary-frontal region in nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198053"} {"pmid": "4198052", "title": "Asymmetrical responses to direction selection for radiation resistance and sensitivity in Drosophila.", "content": "Asymmetrical responses to direction selection for radiation resistance and sensitivity in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198052"} {"pmid": "4198055", "title": "Chromosomal evolution in a rhesus cell line.", "content": "Chromosomal evolution in a rhesus cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198055"} {"pmid": "4198056", "title": "Social behavior comparison in laboratory-reared stumptail and rhesus macaques.", "content": "Social behavior comparison in laboratory-reared stumptail and rhesus macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198056"} {"pmid": "4198054", "title": "An X-O anomaly and ovarian dysgenesis in a rhesus monkey.", "content": "An X-O anomaly and ovarian dysgenesis in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198054"} {"pmid": "4198057", "title": "The reproductive cycles of two subspecies of purple-faced langurs (Presbytic senex) with relation to environmental factors.", "content": "The reproductive cycles of two subspecies of purple-faced langurs (Presbytic senex) with relation to environmental factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198057"} {"pmid": "4198058", "title": "Homosexual behavior and dominance hierarchy in a group of captive female squirrel monkeys (Saimiri sciureus).", "content": "Homosexual behavior and dominance hierarchy in a group of captive female squirrel monkeys (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198058"} {"pmid": "4198059", "title": "Chloroplast membrane proteins. II. Solubilization of the lipophilic components.", "content": "Chloroplast membrane proteins. II. Solubilization of the lipophilic components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198059"} {"pmid": "4198060", "title": "Subunit structure of fragment D from fibrinogen and cross-linked fibrin.", "content": "Subunit structure of fragment D from fibrinogen and cross-linked fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198060"} {"pmid": "4198061", "title": "Polymorphism of rhesus monkey serum prealbumin. Molecular properties and binding of thyroxine and retinol-binding protein.", "content": "Polymorphism of rhesus monkey serum prealbumin. Molecular properties and binding of thyroxine and retinol-binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198061"} {"pmid": "4198062", "title": "Mammary tumor regression. V. Role of acid ribonuclease and cathepsin.", "content": "Mammary tumor regression. V. Role of acid ribonuclease and cathepsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198062"} {"pmid": "4198063", "title": "Mammary tumor regression. VI. Synthesis and degradation of acid ribonuclease.", "content": "Mammary tumor regression. VI. Synthesis and degradation of acid ribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198063"} {"pmid": "4198064", "title": "Purification and comparison of sex-dependent and sex-independent gulonolactonase of rats.", "content": "Purification and comparison of sex-dependent and sex-independent gulonolactonase of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198064"} {"pmid": "4198065", "title": "The relationship of serine protease activity to RNA polymerase modification and sporulation in Bacillus subtilis.", "content": "The relationship of serine protease activity to RNA polymerase modification and sporulation in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198065"} {"pmid": "4198066", "title": "Basal study on early diagnosis of cadmium poisoning: change in carbonic anhydrase activity.", "content": "Basal study on early diagnosis of cadmium poisoning: change in carbonic anhydrase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198066"} {"pmid": "4198067", "title": "Serum immunoglobulins and coproantibody formation in infants after artificial intestinal colonization with Escherichia coli 083 and oral lysozyme administration.", "content": "Serum immunoglobulins and coproantibody formation in infants after artificial intestinal colonization with Escherichia coli 083 and oral lysozyme administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198067"} {"pmid": "4198071", "title": "The biology of human aging.", "content": "The biology of human aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198071"} {"pmid": "4198074", "title": "Studies on human thyroxine-binding globulin. 8. Isoelectric focusing evidence for microheterogeneity of thyroxine-binding globulin.", "content": "Studies on human thyroxine-binding globulin. 8. Isoelectric focusing evidence for microheterogeneity of thyroxine-binding globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198074"} {"pmid": "4198075", "title": "Purification and properties of rat adrenal phenylethanolamine-N-methyl transferase.", "content": "Purification and properties of rat adrenal phenylethanolamine-N-methyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198075"} {"pmid": "4198076", "title": "Studies on the immunological cross-reactivity and physical properties of fatty acid synthetases.", "content": "Studies on the immunological cross-reactivity and physical properties of fatty acid synthetases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198076"} {"pmid": "4198077", "title": "Effect of secondary interaction on the enzymatic activity of trypsin-like enzymes from Streptomyces.", "content": "Effect of secondary interaction on the enzymatic activity of trypsin-like enzymes from Streptomyces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198077"} {"pmid": "4198079", "title": "Intestinal malabsorption in malnourished children and during recovery. Duodenal contents of lipase, nitrogen, and micellar fat after fat stimulation.", "content": "Intestinal malabsorption in malnourished children and during recovery. Duodenal contents of lipase, nitrogen, and micellar fat after fat stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198079"} {"pmid": "4198080", "title": "Solitary mastocytoma.", "content": "Solitary mastocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198080"} {"pmid": "4198081", "title": "The bacterial degradation of flavonoids. Oxidative fission of the A-ring of dihydrogossypetin by a Pseudomonas sp.", "content": "The bacterial degradation of flavonoids. Oxidative fission of the A-ring of dihydrogossypetin by a Pseudomonas sp. Cell-free extracts prepared from a Pseudomonas sp., grown on (+)-catechin, oxidized dihydrogossypetin (3',4',5,7,8-pentahydroxyflavanonol) by cleaving the A-ring to form oxaloacetic acid from C-5, C-6, C-7 and C-8 together with 5-(3,4-dihydroxyphenyl)-4-hydroxy-3-oxovalero-delta-lactone. The structure of this lactone was confirmed by synthesis of related phenylvalerolactones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198081"} {"pmid": "4198084", "title": "Stimulatin of tryptophan metabolism in the rat by 4-dimethylamino-3'methylazobenzene and 2-acetamidofluorene.", "content": "Stimulatin of tryptophan metabolism in the rat by 4-dimethylamino-3'methylazobenzene and 2-acetamidofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198084"} {"pmid": "4198082", "title": "Sporulation in Bacillus subtilis. Properties and time of synthesis of alkali-soluble protein of the spore coat.", "content": "Sporulation in Bacillus subtilis. Properties and time of synthesis of alkali-soluble protein of the spore coat. An alkali-extractable protein fraction comprising 6% of the dry weight of the spore can be removed from spores of Bacillus subtilis 168. Three different extraction procedures each yield at least one similar protein. Extracted protein behaved as a single species on ion-exchange chromatography or gel filtration, but two polypeptides were found on electrophoresis. Comparison of molecular weights on electrophoresis and by sucrosegradient analysis suggests that the protein(s) undergo aggregation into multimers. Extracted spores remain viable, but are altered in density and lysozyme sensitivity and they aggregate together. Electron microscopy of extracted spores shows that loss of material seems to occur from the outer coat layers. Extraction therefore probably removes a specific fraction of the spore-coat protein, but without impairment to the spore protoplast. This protein can first be detected immunologically 4h after the initiation of sporulation, and the synthesis of this protein is sensitive to chloramphenicol, actinomycin D and rifamycin. Labelling experiments also show that the protein begins to be synthesized early in sporulation. Examination of the ability of asporogenous mutants to produce cross-reacting material indicates that some event in stage II of sporulation determines its production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198082"} {"pmid": "4198083", "title": "The uptake and metabolism of plasma lysophosphatidylcholine in vivo by the brain of squirrel monkeys.", "content": "The uptake and metabolism of plasma lysophosphatidylcholine in vivo by the brain of squirrel monkeys. 1. Adult squirrel monkeys were injected intravenously with doubly labelled lysophosphatidylcholine (a mixture of 1-[1-(14)C]palmitoyl-sn-glycero-3-phosphorylcholine and 1-acyl-sn-glycero-3-phosphoryl[Me-(3)H]choline; (3)H:(14)Cratio 3.75) complexed to albumin, and the incorporation into the brain was studied at times up to 3h. 2. After 20min, 1% of the radioactivity injected as lysophosphatidylcholine had been taken up by the brain. 3. Approx. 70% of the doubly labelled lysophosphatidylcholine taken up by both grey and white matter was converted into phosphatidylcholine, whereas about 30% was hydrolysed. 4. The absence of significant radioactivity in the phosphatidylcholine, free fatty acid and water-soluble fractions of plasma up to 30min after injection of doubly labelled lysophosphatidylcholine rules out the possibility that the rapid labelling of these compounds in brain could be due to uptake from or exchange with their counterparts in plasma. 5. The similarity between the (3)H:(14)C ratios of brain phosphatidylcholine and injected lysophosphatidylcholine demonstrates that formation of the former occurred predominantly via direct acylation. 6. Analysis of the water-soluble products from lysophosphatidylcholine catabolism revealed that appreciable glycerophosphoryl-[Me-(3)H]choline did not accumulate in the brain and that radioactivity was incorporated into choline, acetylcholine, phosphorylcholine and betaine. 7. The role of plasma lysophosphatidylcholine as both a precursor of brain phosphatidylcholine and a source of free choline for the brain is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198083"} {"pmid": "4198085", "title": "Possible role of a thiol group in lactose synthetase A protein.", "content": "Possible role of a thiol group in lactose synthetase A protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198085"} {"pmid": "4198087", "title": "Hepatic and extrahepatic reduction of nicotine 1'-N-oxide in rats.", "content": "Hepatic and extrahepatic reduction of nicotine 1'-N-oxide in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198087"} {"pmid": "4198086", "title": "Effect of inducers on the metabolism and excretion of disodium cromoglycate in rats.", "content": "Effect of inducers on the metabolism and excretion of disodium cromoglycate in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198086"} {"pmid": "4198089", "title": "Potentiation and modulation of the immune response of guinea pigs to poorly immunogenic protein-hapten conjugates by pretreatment with the MER fraction of attenuated tubercle bacilli.", "content": "Potentiation and modulation of the immune response of guinea pigs to poorly immunogenic protein-hapten conjugates by pretreatment with the MER fraction of attenuated tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198089"} {"pmid": "4198088", "title": "Asparagine transport in Lactobacillus plantarum and Streptococcus faecalis.", "content": "Asparagine transport in Lactobacillus plantarum and Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198088"} {"pmid": "4198093", "title": "Estimates and estimation errors of hormone secretion, transport and disposal rates in the maternal-fetal system.", "content": "Estimates and estimation errors of hormone secretion, transport and disposal rates in the maternal-fetal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198093"} {"pmid": "4198094", "title": "Development of cortisol binding in the rhesus monkey.", "content": "Development of cortisol binding in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198094"} {"pmid": "4198095", "title": "An analysis of the negative feedback control of gonadotropin secretion utilizing chronic implantation of ovarian steroids in ovariectomized rhesus monkeys.", "content": "An analysis of the negative feedback control of gonadotropin secretion utilizing chronic implantation of ovarian steroids in ovariectomized rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198095"} {"pmid": "4198096", "title": "Effect of synthetic TRF on prolactin release in the sheep.", "content": "Effect of synthetic TRF on prolactin release in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198096"} {"pmid": "4198097", "title": "Risks, research, and reason.", "content": "Risks, research, and reason.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198097"} {"pmid": "4198098", "title": "Pancreatic biogenic amines and insulin secretion in health and disease.", "content": "Pancreatic biogenic amines and insulin secretion in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198098"} {"pmid": "4198099", "title": "Erythrocebus patas--an anatomically suitable primate model for reproductive studies.", "content": "Erythrocebus patas--an anatomically suitable primate model for reproductive studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198099"} {"pmid": "4198100", "title": "Altered immune function in hypercholesterolemic monkeys.", "content": "Altered immune function in hypercholesterolemic monkeys. Humoral and cellular immune responses to several antigens were compared in control and hypercholesterolemic groups of monkeys. Chronic hypercholesterolemia, with concomitant hyperphospholipidemia and hypotriglyceridemia, was produced experimentally by feeding monkeys a high-fat, high-cholesterol diet. When studied prior to infection, hypercholesterolemic monkeys exhibited impaired development of precipitating antibodies against ovalbumin, enhanced sensitivity to tuberculin antigen (stimulated apparently by mycobacterial components in complete Freund adjuvant), and an increased rate of clearance of colloidal carbon from blood. During pneumococcal infection the ability of neutrophiles from hypercholesterolemic monkeys to reduce nitroblue tetrazolium dye showed an increase greater than that of control monkeys; both groups exhibited increased but comparable final clearance rates of colloidal carbon, although the increment of increase was smaller in hypercholesterolemic monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198100"} {"pmid": "4198101", "title": "Extracellular factor synthesized by Bacillus cereus which evokes a dermal reaction in guinea pigs.", "content": "Extracellular factor synthesized by Bacillus cereus which evokes a dermal reaction in guinea pigs. A guinea pig skin assay was developed as a measure of ileal loop fluid-inducing factor in the rabbit and possibly of the causative principle of Bacillus cereus food poisoning. A green or bloody necrotic reaction was produced in the guinea pig skin by injection of culture filtrates from 21 of 24 B. cereus strains tested, and by no other Bacillus species tested except for the closely related B. thuringiensis. The skin factor was synthesized and excreted by logarithmically growing cells, inactivated by heating at 56 C for 5 min, precipitable by ammonium sulfate, and was nondialyzable. The skin activity was not related to the lecithinolytic or hemolytic activities of B. cereus. Production of the skin factor depended on the medium in which the culture was growing. The factor was an antigenically active substance. There are indications that at least two antigenically distinct species of skin factors exist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198101"} {"pmid": "4198102", "title": "Effect of colon flora and short-chain fatty acids on growth in vitro of Pseudomonas aeruginsoa and Enterobacteriaceae.", "content": "Effect of colon flora and short-chain fatty acids on growth in vitro of Pseudomonas aeruginsoa and Enterobacteriaceae. Heat-stable antibacterial activity in the following suspensions was demonstrated against Pseudomonas aeruginosa at pH 6.5, 6.0, and 5.5: (i) pooled colon contents of normal mice; (ii) an anaerobic, 48-h culture of normal mouse feces; and (iii) anaerobic, 48-h cultures of different bacteria from human colon flora (Escherichia coli, Bacteroides fragilis, Klebsiella pneumoniae, and Proteus mirabilis). The lower the pH of the medium, the greater was the antibacterial activity of these suspensions. The antibacterial activity of five fatty acids (propionic, butyric, isobutyric, acetic, and formic acids) was greater against P. aeruginosa than against three Enterobacteriaceae (E. coli, K. pneumoniae, and P. mirabilis) at all fatty acid concentrations (0.16 M to 0.005 M) and at the 3 pH values studied (5.5, 6.0, and 6.5). As the pH value increased, the antibacterial activity decreased. Antibacterial activity was greater at higher fatty acid concentrations, and at each pH value it was greatest for the fatty acids having high pK(a) values. Lactic acid, with the lowest pK(a), exhibited little or no antibacterial activity. Acetic and butyric acids, two of the three predominant volatile fatty acids determined by gas chromatography in the mouse colon contents and in the anaerobic culture of mouse feces, occurred in vivo in concentrations which inhibited growth of P. aeruginosa in vitro at the pH of the mouse cecum. These results suggest that undissociated short-chain fatty acids produced by the colon flora may be a mechanism of intestinal resistance to colonization by P. aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198102"} {"pmid": "4198103", "title": "Relationship between tuberculin hypersensitivity and cellular immunity to infection in mice vaccinated with viable attenuated Mycobacterial cells or with Mycobacterial ribonucleic acid preparations.", "content": "Relationship between tuberculin hypersensitivity and cellular immunity to infection in mice vaccinated with viable attenuated Mycobacterial cells or with Mycobacterial ribonucleic acid preparations. The migration inhibition technique has been used to study delayed hypersensitivity in vitro by using peritoneal exudate cells and splenic lymphocytes from mice vaccinated with viable cells of the attenuated H37Ra strain of Mycobacterium tuberculosis and from mice vaccinated with ribonucleic acid (myc RNA) preparations obtained from viable mycobacterial cells of the same strain. Inhibition of macrophage migration was noted when purified protein derivative (PPD) or viable H37Ra cells were added to peritoneal exudate cells obtained from mice immunized with viable H37Ra cells and not from mice immunized with myc RNA. Splenic lymphocyte cultures were exposed to the same antigens in vitro. Filtered supernatant fluids from these lymphocyte cultures, when added to peritoneal exudate cells obtained from nonimmunized mice, inhibited migration only when they were obtained from lymphocytes which came from mice immunized with viable H37Ra cells. Injection of PPD intravenously into vaccinated mice resulted in inhibitory supernatant fluids from splenic lymphocyte cultures only when the lymphocytes came from mice immunized with viable H37Ra cells. However, intravenous injection of either viable H37Ra cells or of myc RNA preparations into mice vaccinated with myc RNA occasionally produced inhibitory supernatant fluids when lymphocytes were obtained from these mice. On the other hand, mice vaccinated with myc RNA or viable H37Ra cell preparations were consistently and equally protected against intravenous challenge with the virulent H37Rv strain. Thus, although some evidence was obtained for a delayed type hypersensitivity in mice vaccinated with H37Ra cells or with myc RNA to ribosomal proteins or other proteins associated with the RNA preparation, no evidence of tuberculin hypersensitivity could be detected in any mice vaccinated with the myc RNA. These results argue against a role for tuberculin hypersensitivity in immunity to tuberculous infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198103"} {"pmid": "4198104", "title": "Metabolism of Richettsia tsutsugamushi and Rickettsia rickettsi in irradiated host cells.", "content": "Metabolism of Richettsia tsutsugamushi and Rickettsia rickettsi in irradiated host cells. The metabolism of Rickettsia tsutsugamushi (Gilliam strain) multiplying in irradiated L cells was investigated by methods involving the use of (14)C-labeled substrates and cycloheximide, an inhibitor of eukaryotic metabolism. Cycloheximide-resistant amino acid and adenine incorporations were appreciably higher in infected than in uninfected cultures during the period from 3 to 5 or 6 days postinoculation. The metabolism of R. rickettsi was similarly studied in primary duck embryo cells, which are more susceptible to infection with this rickettsia than are L cells. A difference in cycloheximide-resistant activity between infected and uninfected cultures was also noted, but was small. This finding is attributed to the more limited growth of R. rickettsi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198104"} {"pmid": "4198105", "title": "Interaction of gonococci with phagocytic leukocytes from men and mice.", "content": "Interaction of gonococci with phagocytic leukocytes from men and mice. The interaction of human and mouse phagocytic leukocytes with representative virulent (F62-T1) and avirulent (F62-T4, RD-5) strains of Neisseria gonorrhoeae was studied in vitro. Leukocyte monolayers were incubated with gonococci for 30 min at 37 C, washed repeatedly, reincubated with fresh medium, and sampled for viable bacteria at intervals. After the initial incubation period and washing, human leukocytes retained larger numbers of viable T1 than of T4. During the subsequent 120 min of incubation, the numbers of viable T1 remained approximately constant, whereas viable counts of T4 declined by about two-thirds. In contrast, mouse leukocytes under similar conditions destroyed 70% of both types of gonococci. When human bactericidal serum was applied to infected human leukocytes, it had no effect on T4 but inactivated over 50% of T1. It is concluded that T4 are phagocytized by human leukocytes and are thus exposed to internal digestion, but are protected from bactericidal serum. T1, on the other hand, either adhere to the surface of the leukocytes or remain located so that they are neither digested by the leukocytes nor protected from bactericidal serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198105"} {"pmid": "4198107", "title": "Metabolism and excretion of exogenous thyrotropin-releasing hormone in humans.", "content": "Metabolism and excretion of exogenous thyrotropin-releasing hormone in humans. To study the metabolism of thyrotropin-releasing hormone (TRH) in vivo, 400 mug TRH was administered intravenously to eight normal male subjects. Multiple plasma and urine samples were obtained before and after TRH administration. Serum TSH concentrations increased after TRH administration in all subjects. Plasma TRH levels, measured by radioimmunoassay, were undetectable (< 0.4 ng/ml) before TRH administration. Plasma TRH concentrations averaged 33+/-7 ng/ml (mean +/-SEM) 2 min after TRH injection. Thereafter, they decreased rapidly so that the mean plasma TRH level was 2.9 ng/ml 20 min after TRH administration. The fall in plasma TRH levels was linear during this interval. Thereafter TRH levels declined more slowly. The mean half-life (t(1/2)) of TRH was 5.3+/-0.5 min. The mean distribution volume was 15.7+/-3.8 liters, an average of 16.5% of body weight in these subjects. In the urine, 5.5+/-0.9% of the administered TRH was recovered in the 3 h after TRH administration. Of the total urinary TRH recovered, 84.9% was excreted in the first 30 min. These results indicate that TRH is distributed in a large volume, that it is rapidly metabolized and that a significant quantity of administered TRH is excreted in the urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198107"} {"pmid": "4198108", "title": "Endocrine studies in anencephaly.", "content": "Endocrine studies in anencephaly. Endocrine function has been investigated in four anencephalic neonates to determine the influence of absence of cortical and hypothalamic tissue and of hypoplasia of the pituitary. Intravenous glucose administration resulted in higher peak values for blood sugar and more rapid glucose disposal rates than reported in normals. Intravenous insulin tolerance tests on two of the infants failed to evoke elevations in plasma growth hormone, and the infants showed a remarkable resistance to the hypoglycemic effect of insulin. Administration of lysine-vasopressin caused an active growth hormone release. Similarly, there was a large increase in serum thyrotropin after administration of synthetic thyrotropin-releasing hormone. Basal levels of both thyrotropin and growth hormone were low as compared with values reported for normal newborns. Prolactin values obtained on three of the infants were in the normal range. The results strongly suggest that anterior pituitary function mediated by the hypothalamus and its releasing factors is deficient in anencephaly. However, the anterior pituitary can release growth hormone and thyrotropin when stimulated directly and, in the case of thyrotropin release, may function autonomously. The normal prolactin values presumably reflect the absence of the hypothalamic prolactin inhibitory factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198108"} {"pmid": "4198109", "title": "The association of respiratory infection, recurrent hematuria, and focal glomerulonephritis with activation of the complement system in the cold.", "content": "The association of respiratory infection, recurrent hematuria, and focal glomerulonephritis with activation of the complement system in the cold. The study of the activation of C3, C5, and C7 associated with the conversion of C3 in the serum of a 9-yr old girl after incubation at 0 degrees C for 6-8 h without utilization of C1, C4, and C2 is described. The patient has upper respiratory infections associated with recurrent gross hematuria, focal glomerulonephritis, and transient renal insufficiency. Histological lesions demonstrated the presence of B1c globulin IgA and properdin in the glomeruli. The activation of complement (C) in the cold requires the patient's IgA. Removal of IgA from the serum by immunoadsorption prevents activation and conversion of C3. Bactericidal and phagocytic activity is also impaired after incubation. C3 proactivator (C3PA) level is reduced before and after incubation. Properdin level drops after incubation. These findings suggest that the activation of C3 which is demonstrable in vitro may be a continuous process in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198109"} {"pmid": "4198110", "title": "Isolation of Neisseria lactamicus from the nasopharynx.", "content": "Isolation of Neisseria lactamicus from the nasopharynx. During 1971 and 1972, 71 cultures of neisseriae that attacked lactose were received by this laboratory. All strains except one from an eye swab were from the nasopharynx of healthy subjects. Nineteen similar strains from the nasopharynx were isolated in this laboratory. The characteristics of these strains were compared with those of Neisseria meningitidis, Neisseria pharyngis, Neisseria catarrhalis, and Neisseria lactamicus. The 90 strains under investigation closely resembled Neisseria meningitidis but could be differentiated by production of acid from lactose and beta-galactosidase activity and were therefore classified as Neisseria lactamicus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198110"} {"pmid": "4198111", "title": "Cross immunity studies with East and West African strains of Plasmodium falciparum in owl monkeys (Aotus trivirgatus).", "content": "Cross immunity studies with East and West African strains of Plasmodium falciparum in owl monkeys (Aotus trivirgatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198111"} {"pmid": "4198112", "title": "Evaluation of the complement fixation test in diagnosis of actinomycetoma.", "content": "Evaluation of the complement fixation test in diagnosis of actinomycetoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198112"} {"pmid": "4198113", "title": "Autoantibodies in schistosomal liver fibrosis.", "content": "Autoantibodies in schistosomal liver fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198113"} {"pmid": "4198114", "title": "Neonatal gonococcal infection. I. Orogastric contamination with Neisseria gonorrhoea.", "content": "Neonatal gonococcal infection. I. Orogastric contamination with Neisseria gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198114"} {"pmid": "4198106", "title": "Free fatty acid content of cacao beans infested with storage fungi.", "content": "Free fatty acid content of cacao beans infested with storage fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198106"} {"pmid": "4198116", "title": "Effect of MDMP on protein synthesis in wheat and bacteria.", "content": "Effect of MDMP on protein synthesis in wheat and bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198116"} {"pmid": "4198115", "title": "Altered enzyme molecules in senescent organisms: mouse muscle aldolase.", "content": "Altered enzyme molecules in senescent organisms: mouse muscle aldolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198115"} {"pmid": "4198121", "title": "An angiographic study of the meningorachidian venous system.", "content": "An angiographic study of the meningorachidian venous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198121"} {"pmid": "4198122", "title": "Simple measurement of chest-wall thickness with ultrasound.", "content": "Simple measurement of chest-wall thickness with ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198122"} {"pmid": "4198123", "title": "Reemphasis on tuberculosis.", "content": "Reemphasis on tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198123"} {"pmid": "4198124", "title": "Accommodative vergence in the alert monkey. Motor unit analysis.", "content": "Accommodative vergence in the alert monkey. Motor unit analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198124"} {"pmid": "4198125", "title": "Early malnutrition and brain development.", "content": "Early malnutrition and brain development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198125"} {"pmid": "4198127", "title": "The neurocranial basis for facial form and pattern.", "content": "The neurocranial basis for facial form and pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198127"} {"pmid": "4198128", "title": "Environmental factors internal to the host that affect the sucess of microbial insecticides.", "content": "Environmental factors internal to the host that affect the sucess of microbial insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198128"} {"pmid": "4198129", "title": "Effects of entomopathogens on vertebrates.", "content": "Effects of entomopathogens on vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198129"} {"pmid": "4198131", "title": "Enzootic diseases of insects.", "content": "Enzootic diseases of insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198131"} {"pmid": "4198130", "title": "Environmental impact of insect control by microorganisms.", "content": "Environmental impact of insect control by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198130"} {"pmid": "4198132", "title": "Perspectives of biological insect control.", "content": "Perspectives of biological insect control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198132"} {"pmid": "4198133", "title": "Means for insect regulation. Microbial toxins.", "content": "Means for insect regulation. Microbial toxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198133"} {"pmid": "4198134", "title": "Determination of the molecular weight in nucleic acids by end-phosphate analysis.", "content": "Determination of the molecular weight in nucleic acids by end-phosphate analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198134"} {"pmid": "4198135", "title": "Properties of oligodeoxynucleotides that determine priming activity with Escherichia coli deoxyribonucleic acid polymerase I.", "content": "Properties of oligodeoxynucleotides that determine priming activity with Escherichia coli deoxyribonucleic acid polymerase I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198135"} {"pmid": "4198119", "title": "The role of nutrition in the physiological and behavioral effects of early maternal separation on infant rats.", "content": "The role of nutrition in the physiological and behavioral effects of early maternal separation on infant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198119"} {"pmid": "4198136", "title": "Electron microscopy of Bacillus subtilis protoplast membrane after treatment with phospholipase A 2 and phospholipase C.", "content": "Electron microscopy of Bacillus subtilis protoplast membrane after treatment with phospholipase A 2 and phospholipase C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198136"} {"pmid": "4198120", "title": "Electrocardiographic and cardiac morphological changes associated with environmental stress in squirrel monkeys.", "content": "Electrocardiographic and cardiac morphological changes associated with environmental stress in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198120"} {"pmid": "4198138", "title": "The effects of propionate on sodium transport by the toad bladder. Evidence for a metabolic mode of action.", "content": "The effects of propionate on sodium transport by the toad bladder. Evidence for a metabolic mode of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198138"} {"pmid": "4198137", "title": "Permeability of Azotobacter vinelandii to cations and anions.", "content": "Permeability of Azotobacter vinelandii to cations and anions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198137"} {"pmid": "4198139", "title": "Adenine nucleotide metabolism of blood platelets. 8. Transport of adenine into human platelets.", "content": "Adenine nucleotide metabolism of blood platelets. 8. Transport of adenine into human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198139"} {"pmid": "4198140", "title": "Denaturation and reactivation of human carbonic anhydrases in guanidine hydrochloride and urea.", "content": "Denaturation and reactivation of human carbonic anhydrases in guanidine hydrochloride and urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198140"} {"pmid": "4198141", "title": "Detection of proteolytic activity after isoelectric focusing in polyacrylamide gel.", "content": "Detection of proteolytic activity after isoelectric focusing in polyacrylamide gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198141"} {"pmid": "4198142", "title": "Modified erythrocytes in indirect haemagglutination with Neisseria gonorrhoeae antigen.", "content": "Modified erythrocytes in indirect haemagglutination with Neisseria gonorrhoeae antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198142"} {"pmid": "4198143", "title": "Penicillin sensitivity of gonococci in Ethiopia.", "content": "Penicillin sensitivity of gonococci in Ethiopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198143"} {"pmid": "4198145", "title": "On the localization of ribonucleases in bacteria.", "content": "On the localization of ribonucleases in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198145"} {"pmid": "4198144", "title": "Intrarenal distribution of blood flow in the baboon: effect of noradrenaline and adrenergic blocking agents.", "content": "Intrarenal distribution of blood flow in the baboon: effect of noradrenaline and adrenergic blocking agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198144"} {"pmid": "4198146", "title": "Skeletal muscle phosphorylase kinase deficiency: detection of a protein lacking any activity in ICR-IAn mice.", "content": "Skeletal muscle phosphorylase kinase deficiency: detection of a protein lacking any activity in ICR-IAn mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198146"} {"pmid": "4198148", "title": "Brief communication: processed soya flour as substitute for dry skim milk in the \"protein packet\" in the treatment of protein calorie malnutrition.", "content": "Brief communication: processed soya flour as substitute for dry skim milk in the \"protein packet\" in the treatment of protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198148"} {"pmid": "4198147", "title": "Nutritional status of rural pre-school children in West Bengal: II clinical observations.", "content": "Nutritional status of rural pre-school children in West Bengal: II clinical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198147"} {"pmid": "4198150", "title": "Effect of Aspergillus flavus mycotoxin on Culex mosquito larvae.", "content": "Effect of Aspergillus flavus mycotoxin on Culex mosquito larvae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198150"} {"pmid": "4198151", "title": "Larval mortality of Culex tarsalis and Aedes aegypti when reared with different concentrations of Tetrahymena pyriformis.", "content": "Larval mortality of Culex tarsalis and Aedes aegypti when reared with different concentrations of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198151"} {"pmid": "4198152", "title": "Identification of members of the Culex pipiens complex by immunodiffusion and immunoelectrophoresis.", "content": "Identification of members of the Culex pipiens complex by immunodiffusion and immunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198152"} {"pmid": "4198153", "title": "Clinical response to disodium cromoglycate. A double blind study.", "content": "Clinical response to disodium cromoglycate. A double blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198153"} {"pmid": "4198154", "title": "Factors affecting the turnover of cerebral glycogen and limit dextrin in vivo.", "content": "Factors affecting the turnover of cerebral glycogen and limit dextrin in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198154"} {"pmid": "4198155", "title": "Isolation and characterization of an organ specific ribonucleoprotein from goat brain.", "content": "Isolation and characterization of an organ specific ribonucleoprotein from goat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198155"} {"pmid": "4198156", "title": "Lysolecithin and sphingosinephosphoryl-choline in the metabolism of brain phospholipids of the rhesus monkey (Macaca mulatta): effects of development.", "content": "Lysolecithin and sphingosinephosphoryl-choline in the metabolism of brain phospholipids of the rhesus monkey (Macaca mulatta): effects of development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198156"} {"pmid": "4198161", "title": "Lactose content of tube feeding diets as a cause of diarrhea.", "content": "Lactose content of tube feeding diets as a cause of diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198161"} {"pmid": "4198163", "title": "The treatment of self-induced photic epilepsy.", "content": "The treatment of self-induced photic epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198163"} {"pmid": "4198164", "title": "Reconsideration of the role of serotonin in subarachnoid haemorrhage.", "content": "Reconsideration of the role of serotonin in subarachnoid haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198164"} {"pmid": "4198165", "title": "Immunologic relationships of antihemophilic factor of different species detected by specific human and rabbit antibodies.", "content": "Immunologic relationships of antihemophilic factor of different species detected by specific human and rabbit antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198165"} {"pmid": "4198167", "title": "The use of an immunoadsorbent in the isolation of Australia antigen.", "content": "The use of an immunoadsorbent in the isolation of Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198167"} {"pmid": "4198168", "title": "Tissue and organ culture studies of hepatitis type B.", "content": "Tissue and organ culture studies of hepatitis type B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198168"} {"pmid": "4198169", "title": "Radioimmunoprecipitation assay for Australia antibody.", "content": "Radioimmunoprecipitation assay for Australia antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198169"} {"pmid": "4198166", "title": "Development of antilymphocyte sera by cross immunization of chimpanzees and baboons.", "content": "Development of antilymphocyte sera by cross immunization of chimpanzees and baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198166"} {"pmid": "4198162", "title": "Alveolar bone changes consequent to orthodontic forces. A tetracycline marking study.", "content": "Alveolar bone changes consequent to orthodontic forces. A tetracycline marking study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198162"} {"pmid": "4198170", "title": "Hepatitis: intrahepatic expression of Au antigen and immune complexes in liver tissue.", "content": "Hepatitis: intrahepatic expression of Au antigen and immune complexes in liver tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198170"} {"pmid": "4198171", "title": "Australia antigen in cord blood.", "content": "Australia antigen in cord blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198171"} {"pmid": "4198173", "title": "Blood bank service screening of Australia antigen and antibodies at Mainz, Germany.", "content": "Blood bank service screening of Australia antigen and antibodies at Mainz, Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198173"} {"pmid": "4198172", "title": "Australia antigen and antibody in laboratory and other hospital personnel.", "content": "Australia antigen and antibody in laboratory and other hospital personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198172"} {"pmid": "4198174", "title": "Repeated monitoring of Au-SH antigen in blood donors of Reggio Emilia.", "content": "Repeated monitoring of Au-SH antigen in blood donors of Reggio Emilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198174"} {"pmid": "4198175", "title": "Low voltage counterimmunoelectrophoresis for the detection of Australia antigen.", "content": "Low voltage counterimmunoelectrophoresis for the detection of Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198175"} {"pmid": "4198176", "title": "Amodification of the immunoelectrophoretic method in the detection of Australia antigen.", "content": "Amodification of the immunoelectrophoretic method in the detection of Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198176"} {"pmid": "4198177", "title": "Primates as model for human viral hepatitis: transmission of infection by human hepatitis B virus.", "content": "Primates as model for human viral hepatitis: transmission of infection by human hepatitis B virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198177"} {"pmid": "4198178", "title": "Gas-chromatographic determination of selenium.", "content": "Gas-chromatographic determination of selenium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198178"} {"pmid": "4198180", "title": "Arthritis and HB Ag-positive hepatitis.", "content": "Arthritis and HB Ag-positive hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198180"} {"pmid": "4198179", "title": "Antithymocyte antisera globulin effect on human lymphoid neoplasia.", "content": "Antithymocyte antisera globulin effect on human lymphoid neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198179"} {"pmid": "4198181", "title": "Steroid-responsive hypercalcemia in disseminated bone tuberculosis.", "content": "Steroid-responsive hypercalcemia in disseminated bone tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198181"} {"pmid": "4198182", "title": "Metabolic and microcirculatory effects of glucagon in hypovolemic shock.", "content": "Metabolic and microcirculatory effects of glucagon in hypovolemic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198182"} {"pmid": "4198183", "title": "Experience with elemental diet in the treatment of inflammatory bowel disease. Is this primary therapy?", "content": "Experience with elemental diet in the treatment of inflammatory bowel disease. Is this primary therapy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198183"} {"pmid": "4198184", "title": "Energy-dependent accumulation of iron by isolated rat liver mitochondria. I. General features.", "content": "Energy-dependent accumulation of iron by isolated rat liver mitochondria. I. General features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198184"} {"pmid": "4198185", "title": "Light-induced changes in the fluorescence yield of chlorophyll a in Anacystis nidulans. I. Relationship of slow fluorescence changes with structural changes.", "content": "Light-induced changes in the fluorescence yield of chlorophyll a in Anacystis nidulans. I. Relationship of slow fluorescence changes with structural changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198185"} {"pmid": "4198186", "title": "Chromatographic separation of two ionic strength dependent conformations of valine transfer ribonucleic acid of Bacillus subtilis.", "content": "Chromatographic separation of two ionic strength dependent conformations of valine transfer ribonucleic acid of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198186"} {"pmid": "4198187", "title": "Selective reaction of glyoxal with guanine residues in native and denatured Escherichia coli 5S RNA.", "content": "Selective reaction of glyoxal with guanine residues in native and denatured Escherichia coli 5S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198187"} {"pmid": "4198188", "title": "Formation of ribosomal particles in virginiamycin sensitive and resistant mutants of Bacillus subtilis.", "content": "Formation of ribosomal particles in virginiamycin sensitive and resistant mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198188"} {"pmid": "4198192", "title": "A comparative clinical evaluation of hepatitis-associated antigen detection.", "content": "A comparative clinical evaluation of hepatitis-associated antigen detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198192"} {"pmid": "4198193", "title": "Salivary immunoglobulins in Sjögren's syndrome.", "content": "Salivary immunoglobulins in Sjögren's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198193"} {"pmid": "4198194", "title": "Measurements of concentrations of human serum innunoglobulins.", "content": "Measurements of concentrations of human serum innunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198194"} {"pmid": "4198195", "title": "Response of plasma histaminase activity to small doses of heparin in normal subjects and patients with hyperlipoproteinemia.", "content": "Response of plasma histaminase activity to small doses of heparin in normal subjects and patients with hyperlipoproteinemia. The release of histaminase activity in plasma after small intravenous of heparin was studied in 85 normal subjects and patients. In normal subjects, plasma histaminase activity (basal level, 1.7+/-0.1 U/ml, mean +/-SEM) increased 1.6+/-0.2 U/ml after 10 U of heparin/kg, 8.5+/-2.4 U/ml after 20 U/kg, and 33+/-4.9 U/ml after 75 U/kg. The extent of the increase varied widely among individuals but in a particular individual the response was constant and dose-dependent. Histaminase activity rose to peak levels within 7-15 min and then declined exponentially with a half-life of 40-120 min. This pattern of response was also observed in two patients with the histaminase-producing tumor, medullary carcinoma of the thyroid. A significantly reduced response was observed, however, in 14 patients with type I hyperlipoproteinemia, a disorder in which high plasma triglyceride levels are associated with low postheparin plasma lipolytic activity. After 10 U heparin/kg, plasma histamine activity increased 0.5+/-0.2 U/ml, and after 75 U heparin/kg, 10.9+/-5.6 U/ml. In contrast, in 27 patients with other types of hyperlipoproteinemia in whom postheparin lipolytic activity was normal, the increase (2.4+/-0.6 U/ml) in plasma histaminase activity after 10 U heparin/kg was not significantly different from that of normal subjects. The reduced response of the plasma histaminase activity to heparin in patients with type I hyperlipoproteinemia did not appear to be due to the presence of lipemia or to an inhibitor of the enzyme in plasma. These findings suggest that many patients with type I hyperlipoproteinemia may have deficient release of both lipolytic and histaminase activities into plasma after heparin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198195"} {"pmid": "4198196", "title": "A saturable, vasopressin-sensitive carrier for urea and acetamide in the toad bladder epithelial cell.", "content": "A saturable, vasopressin-sensitive carrier for urea and acetamide in the toad bladder epithelial cell. The permeability of the toad bladder to a series of isotopically labeled nonelectrolytes was determined in the presence of 150 mM unlabeled acetamide. Under these conditions, overall bladder function was unimpaired, as shown by a normal response to vasopressin of short-circuit current and permeability coefficient of [(3)H]water,[(14)C]ethanol, and [(14)C]propionamide. The permeability of the bladder to isotopic acetamide and urea, however, was significantly depressed by unlabeled acetamide, in both the absence and presence of vasopressin. These experiments indicate a competition between unlabeled and isotopic species for binding sites, and show the existence of a saturable, vasopressin-sensitive carrier for urea and acetamide in the epithelial cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198196"} {"pmid": "4198199", "title": "Cellular mediators of anti-Listeria immunity as an enlarged population of short lived, replicating T cells. Kinetics of their production.", "content": "Cellular mediators of anti-Listeria immunity as an enlarged population of short lived, replicating T cells. Kinetics of their production. An intravenous immunizing infection with the facultative, intracellular parasite, Listeria monocytogenes results in the production in the spleen of a population of immunologically-committed lymphocytes which can adoptively immunize normal recipients against a lethal challenge infection. These cellular mediators of immunity are first produced in the spleen between days 2 and 4 of infection and reach peak production on day 6. Their production then progressively decreases until about day 20 when their presence can no longer be detected. Increased production of cellular mediators is coincident with major increases in cell division, cellularity, and spleen weight. Decreased production of cellular mediators, on the other hand, is associated with decreases in cell division, cellularity, and spleen weight. Again, the level of delayed sensitivity to Listeria antigens expressed by the host at any one time is proportional to the number of cellular mediators in the spleen. Increased production of cellular mediators is also associated with major increases in the total numbers of replicating T cells and B cells in the spleen. That the cellular mediators of immunity are part of the replicating T cell population, rather than the B cell population, is evidenced by their susceptibility to anti-theta serum and by their resistance to anti-Ig serum. Furthermore, they can be completely eliminated from the spleen by a brief pulse of the antimitotic drug, vinblastine. This study allows the conclusion that the cellular mediators of anti-Listeria immunity belong to an expanded population of rapidly dividing, short-lived T cells. It is suggested that they have the same properties as the T cell effectors of allograft immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198199"} {"pmid": "4198200", "title": "Immunologic studies of the major nonimmunoglobulin protein of amyloid. I. Identification and partial characterization of a related serum component.", "content": "Immunologic studies of the major nonimmunoglobulin protein of amyloid. I. Identification and partial characterization of a related serum component. Antisera have been prepared against the major nonimmunoglobulin component of secondary and familial Mediterranean fever (FMF) associated amyloid which has been called A component or acid soluble fraction (ASF). The antisera were shown to be monospecific for ASF by precipitation of (125)I-labeled antigen and gave a reaction of identity with four different ASF preparations. The antisera were able to detect a circulating component in human serum that migrated in the alpha1-globulin region. This circulating component gave a line of identity with degraded ASF by double immunodiffusion. 57 normal sera and 89 sera from patients with diseases known to be frequently associated with amyloidosis were tested by immunodiffusion for the circulating ASF component. 7% of normal sera and 50-80% of the pathologic sera had elevated amounts of this component. Absorption studies showed that all normal sera probably have small amounts of this component while cord sera do not have detectable amounts. This component was partially purified and was shown to be slightly larger than albumin. The relation of the circulating component to the acid soluble fraction of amyloid is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198200"} {"pmid": "4198201", "title": "Phylogenetically associated residues within the VH3 subgroup of several mammalian species. Evidence for a \"pauci-gene\" basis for antibody diversity.", "content": "Phylogenetically associated residues within the VH3 subgroup of several mammalian species. Evidence for a \"pauci-gene\" basis for antibody diversity. Immunoglobulin heavy chains from IgG pools of several mammalian species have been subjected to Edman degradation on an automated protein sequencer. The percentage of unblocked vs. blocked heavy chains was estimated from the yield of the invariant valine in the second position. Further analysis of these unblocked polypeptides unequivocally placed them in the V(HIII) subgroup on the basis of homology with known human heavy chain sequences. The mammals studied could be divided into three distinct categories on the basis of the distribution of the V(HIII) subgroup. In several species the V(HIII) subgroup could not be detected while, in others, virtually all of the heavy chains belonged to this subgroup. Several species had intermediate amounts with the level of the V(HIII) subgroup restricted to between 19 and 29% of the total pool. Within experimental error, all members of a given order had a similar V(HIII) subgroup distribution. Further amino acid sequence studies illustrated a high degree of structural homogeneity in the heavy chains of IgG isolated from pooled sera of a number of mammalian species. The very close amino acid sequence homologies of the amino terminal 24 residues of the various pools corroborated conclusions previously obtained using several myeloma proteins from some of these same species. In particular, certain phylogenetically associated residues were identifiable at characteristic positions in the pools in confirmation of their identification in the myeloma proteins. The simplest assumptions would suggest that these findings are more compatible with a pauci-gene than a multi-gene basis for the generation of antibody diversity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198201"} {"pmid": "4198202", "title": "The nature of the antibody response to Yersinia enterocolitica serotype IX in cattle.", "content": "The nature of the antibody response to Yersinia enterocolitica serotype IX in cattle. The nature of the antibody response of cattle to the antigen of Yersinia enterocolitica IX cross-reacting with Brucella spp. was examined. Density-gradient ultracentrifugation, ion-exchange chromatography, antibody adsorption and elution and disulphide bond reduction tests showed that both 19 S IgM and 7 S IgG(1) and IgG(2) antibodies were produced in response to the cross-reacting antigen. The highest titres of cross-reacting antibodies were detected by the agglutination and Coombs antiglobulin tests. Production of complement-fixing and precipitating antibodies cross-reacting with Br. abortus was transient and high titres were not attained.In contrast, although infection with Br. abortus also evoked cross-reacting antibodies of the IgM and IgG classes, much higher titres were produced in the complement fixation and precipitation tests and these persisted for long periods. At all stages of the serological response to both organisms, the two infections could be differentiated by the quantitative Rose Bengal plate test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198202"} {"pmid": "4198203", "title": "Typing of Pseudomonas aeruginosa: comparison of the phage procedure with the pyocine technique.", "content": "Typing of Pseudomonas aeruginosa: comparison of the phage procedure with the pyocine technique. Two hundred and sixty strains of Pseudomonas aeruginosa were isolated from patients of the Asaf Harofe Government Hospital. The strains were typed by phage technique and 64 of them were also typed according to pyocine sensitivity. The two methods proved complementary, and reduced the number of untypable strains. Phage typing was performed with both routine test dilution (RTD) and more concentrated phage suspensions. The most reliable results were obtained at 100 RTD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198203"} {"pmid": "4198197", "title": "Oral microbial profile of the marmoset.", "content": "Oral microbial profile of the marmoset.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198197"} {"pmid": "4198204", "title": "A common antigenic constituent in various purified Salmonella endotoxins.", "content": "A common antigenic constituent in various purified Salmonella endotoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198204"} {"pmid": "4198205", "title": "Host resistance to bacterial endotoxemia: mechanisms in endotoxin-tolerant animals.", "content": "Host resistance to bacterial endotoxemia: mechanisms in endotoxin-tolerant animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198205"} {"pmid": "4198206", "title": "Factors in normal human serum that promote bacterial phagocytosis.", "content": "Factors in normal human serum that promote bacterial phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198206"} {"pmid": "4198207", "title": "Escherichia coli bacteremia in the squirrel monkey: demonstration of a complement-dependent neutrophil response.", "content": "Escherichia coli bacteremia in the squirrel monkey: demonstration of a complement-dependent neutrophil response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198207"} {"pmid": "4198208", "title": "Head injury in the chimpanzee. 1. Biodynamics of traumatic unconsciousness.", "content": "Head injury in the chimpanzee. 1. Biodynamics of traumatic unconsciousness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198208"} {"pmid": "4198209", "title": "Head injury in the chimpanzee. 2. Spontaneous and evoked epidural potentials as indices of injury severity.", "content": "Head injury in the chimpanzee. 2. Spontaneous and evoked epidural potentials as indices of injury severity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198209"} {"pmid": "4198210", "title": "Feedlot performance and blood plasma amino acid patterns in beef steers fed diethylstilbestrol under ad libitum, restricted, and compensatory conditions.", "content": "Feedlot performance and blood plasma amino acid patterns in beef steers fed diethylstilbestrol under ad libitum, restricted, and compensatory conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198210"} {"pmid": "4198211", "title": "Effects of dietary zinc on zinc enzymes in the rat.", "content": "Effects of dietary zinc on zinc enzymes in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198211"} {"pmid": "4198213", "title": "Long-standing traumatic lesions of the hypothalamus.", "content": "Long-standing traumatic lesions of the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198213"} {"pmid": "4198198", "title": "Solubility of calcified dental tissues and of calculus in EDTA and 2 percent NaF.", "content": "Solubility of calcified dental tissues and of calculus in EDTA and 2 percent NaF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198198"} {"pmid": "4198212", "title": "Effect of chelating agents on chromium absorption in rats.", "content": "Effect of chelating agents on chromium absorption in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198212"} {"pmid": "4198214", "title": "Influence of dietary protein deficiency on phagocytic activity of the reticulo-endothelial cells.", "content": "Influence of dietary protein deficiency on phagocytic activity of the reticulo-endothelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198214"} {"pmid": "4198216", "title": "Neurofibromatosis of the bladder.", "content": "Neurofibromatosis of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198216"} {"pmid": "4198215", "title": "Self-administration of acetylsalicylic acid and combinations with codeine and caffeine in rhesus monkeys.", "content": "Self-administration of acetylsalicylic acid and combinations with codeine and caffeine in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198215"} {"pmid": "4198217", "title": "Presence of beta-aspartyl N-acetyl glucosamine amido hydrolase in mammalian spermatozoa.", "content": "Presence of beta-aspartyl N-acetyl glucosamine amido hydrolase in mammalian spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198217"} {"pmid": "4198218", "title": "Release of LH by synthetic LH-RH in the monkey, Macaca fascicularis.", "content": "Release of LH by synthetic LH-RH in the monkey, Macaca fascicularis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198218"} {"pmid": "4198220", "title": "Cellular location of the lipoteichoic acids of Lactobacillus fermenti NCTC 6991 and Lactobacillus casei NCTC 6375.", "content": "Cellular location of the lipoteichoic acids of Lactobacillus fermenti NCTC 6991 and Lactobacillus casei NCTC 6375.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198220"} {"pmid": "4198219", "title": "The association of zinc with some components of boar vesicular secretion and seminal plasma. I. Gel-filtration and dialysis studies.", "content": "The association of zinc with some components of boar vesicular secretion and seminal plasma. I. Gel-filtration and dialysis studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198219"} {"pmid": "4198222", "title": "Brain-damaging potential of protein hydrolysates.", "content": "Brain-damaging potential of protein hydrolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198222"} {"pmid": "4198223", "title": "Public accountability and reporting systems in Medicare and other health programs.", "content": "Public accountability and reporting systems in Medicare and other health programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198223"} {"pmid": "4198224", "title": "Safety of hydrolysates in parenteral nutrition.", "content": "Safety of hydrolysates in parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198224"} {"pmid": "4198225", "title": "Positive brain scans in children with idiopathic focal epileptic seizures.", "content": "Positive brain scans in children with idiopathic focal epileptic seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198225"} {"pmid": "4198226", "title": "Transmissible mink encephalopathy agent in squirrel monkeys. Serial electroencephalographic, clinical and pathologic studies.", "content": "Transmissible mink encephalopathy agent in squirrel monkeys. Serial electroencephalographic, clinical and pathologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198226"} {"pmid": "4198229", "title": "Control circuits for determination and transdetermination.", "content": "Control circuits for determination and transdetermination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198229"} {"pmid": "4198232", "title": "Cytological, biochemical and bacteriological data of the hemolymph of Vespaorientalis.", "content": "Cytological, biochemical and bacteriological data of the hemolymph of Vespaorientalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198232"} {"pmid": "4198234", "title": "Factors influencing neonatal infection by hepatitis B virus.", "content": "Factors influencing neonatal infection by hepatitis B virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198234"} {"pmid": "4198231", "title": "The need for further data.", "content": "The need for further data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198231"} {"pmid": "4198230", "title": "Fabry's disease: general clinical aspects.", "content": "Fabry's disease: general clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198230"} {"pmid": "4198250", "title": "A cytogenetic analysis of oocytes from Macaca mulatta and nemestrina matured in vitro.", "content": "A cytogenetic analysis of oocytes from Macaca mulatta and nemestrina matured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198250"} {"pmid": "4198251", "title": "Detection of Australia antigen in Indian childhood cirrhosis.", "content": "Detection of Australia antigen in Indian childhood cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198251"} {"pmid": "4198252", "title": "Role of bound ADP in photosynthetic ATP formation by chromatophores from Rhodospirillum rubrum.", "content": "Role of bound ADP in photosynthetic ATP formation by chromatophores from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198252"} {"pmid": "4198253", "title": "Internal localization of nucleoside-catabolic enzymes in Escherichia coli.", "content": "Internal localization of nucleoside-catabolic enzymes in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198253"} {"pmid": "4198254", "title": "Two types of soluble malic enzyme in rat tissues.", "content": "Two types of soluble malic enzyme in rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198254"} {"pmid": "4198257", "title": "Supervoltage orbital radiotherapy for Graves' ophthalmopathy.", "content": "Supervoltage orbital radiotherapy for Graves' ophthalmopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198257"} {"pmid": "4198259", "title": "Serum levels of luteinizing hormone, follicle-stimulating hormone and progesterone throughout the mentrual cycle of rhesus monkeys.", "content": "Serum levels of luteinizing hormone, follicle-stimulating hormone and progesterone throughout the mentrual cycle of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198259"} {"pmid": "4198256", "title": "Progressive decrease in serum triiodothyronine concentrations with human aging: radioimmunoassay following extraction of serum.", "content": "Progressive decrease in serum triiodothyronine concentrations with human aging: radioimmunoassay following extraction of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198256"} {"pmid": "4198255", "title": "Immunoassay of thyroxine in unextracted human serum.", "content": "Immunoassay of thyroxine in unextracted human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198255"} {"pmid": "4198260", "title": "Elevations in plasma growth hormone concentration after luteinizing hormone-releasing hormone (LRH) in patients with active acromegaly.", "content": "Elevations in plasma growth hormone concentration after luteinizing hormone-releasing hormone (LRH) in patients with active acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198260"} {"pmid": "4198267", "title": "Light induced changes in ionic flux in the retinal rod.", "content": "Light induced changes in ionic flux in the retinal rod.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198267"} {"pmid": "4198266", "title": "Synthesis of lysine from alpha, epsilon-diaminopimelic acid by mixed ciliated rumen protozoa.", "content": "Synthesis of lysine from alpha, epsilon-diaminopimelic acid by mixed ciliated rumen protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198266"} {"pmid": "4198258", "title": "A goitrous subject with defective synthesis of diiodotyrosine due to thyroglobulin abnormalities.", "content": "A goitrous subject with defective synthesis of diiodotyrosine due to thyroglobulin abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198258"} {"pmid": "4198268", "title": "Gonococcal infections in the female.", "content": "Gonococcal infections in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198268"} {"pmid": "4198269", "title": "Gonorrhea among females in a military population.", "content": "Gonorrhea among females in a military population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198269"} {"pmid": "4198271", "title": "Photoreactivation of Drosophila melanogaster embryonic cells.", "content": "Photoreactivation of Drosophila melanogaster embryonic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198271"} {"pmid": "4198270", "title": "Gestational meconium in the high-risk pregnancy.", "content": "Gestational meconium in the high-risk pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198270"} {"pmid": "4198274", "title": "Gap junctions between photoreceptor cells in the vertebrate retina.", "content": "Gap junctions between photoreceptor cells in the vertebrate retina. In the outer plexiform layer of the retina the synaptic endings of cone cells make specialized junctions with each other and with the endings of rod cells. The ultrastructure of these interreceptor junctions is described in retinas of monkeys, rabbits, and turtles, in thin sections of embedded specimens and by the freeze-fracturing technique. Cone-to-rod junctions are ribbon-like areas of close membrane approximation. On either side of the narrowing of the intercellular space, the junctional membranes contain a row of particles located on the fracture face A (cytoplasmic leaflet), while the complementary element, a row of single depressions, is located on fracture face B. The particle rows are surrounded by a membrane region that is devoid of particulate inclusions and bears an adherent layer of dense cytoplasmic material. Cone-to-cone junctions in some places are identical to cone-to-rod junctions, while in other places they closely resemble typical gap junctions (nexus). Interreceptor junctions, therefore, represent a morphological variant of the gap junction, and probably mediate electrotonic coupling between neighboring photoreceptor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198274"} {"pmid": "4198275", "title": "The use of iodinated RNA for gene localization.", "content": "The use of iodinated RNA for gene localization. Carrier-free iodination of 5S RNA with (125)I yields a probe suitable for use in cytological RNA-DNA hybridization studies. The genes coding for 5S ribosomal RNA in Drosophila could be localized by autoradiography after a 2-day exposure, whereas a 2-month exposure is needed when the best available [(3)H]RNA is used. The procedure introduces one covalently bound (125)I atom per 100 nucleotides, resulting in a specific activity of over 10(8) dpm/mug of RNA. The method may be readily applied to other problems involving molecular hybridization techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198275"} {"pmid": "4198277", "title": "Relative orientation with respect to the centromere of ribosomal RNA genes of the X and Y chromosomes of Drosophila melanogaster.", "content": "Relative orientation with respect to the centromere of ribosomal RNA genes of the X and Y chromosomes of Drosophila melanogaster. We tested for recombination within the DNA that codes for ribosomal RNA (rDNA) on the X and Y chromosomes of Drosophila melanogaster. The criterion was the appearance of intermediate bb alleles on X-Y recombinants from wild bb(+) and lethal bb(1) loci carried on parental chromosomes. Recombination within the rDNA occurs only when the rDNA of the X chromosome is inverted. We conclude that rDNAs of normal X and Y chromosomes have opposite orientation with respect to the centromere. The implications of this observation are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198277"} {"pmid": "4198276", "title": "Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation.", "content": "Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation. The activity of the sigma subunit of the RNA polymerase of Bacillus subtilis decreases markedly during the first 2 hr of sporulation. Moreover, sigma activity remains deficient throughout the sporulation process and in dormant spores. The time course of changes in RNA polymerase during sporulation indicates that alterations in the core of RNA polymerase occur after the loss of sigma activity. Core RNA polymerase purified after the second and before the ninth hour of sporulation fails to respond to vegetative sigma subunit in vitro and contains variable amounts of a 110,000-dalton polypeptide in place of the beta' subunit. Core RNA polymerase purified from dormant spores has a subunit structure indistinguishable from vegetative core enzyme.RNA polymerase purified by antibody precipitation from an extract of a mixture of sporulating and excess vegetative cells separately labeled with two different radioisotopes contains beta' subunit and no 110,000-dalton polypeptide. However, RNA polymerase purified from sporulating bacteria in the absence of excess vegetative cells progressively loses the beta' subunit at each stage of purification even in the presence of the protease inhibitor, phenylmethyl sulfonyl fluoride. These findings suggest that the alteration of the beta' subunit is due to proteolysis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198276"} {"pmid": "4198278", "title": "The aflatoxins and human liver cancer.", "content": "The aflatoxins and human liver cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198278"} {"pmid": "4198280", "title": "Evaluation of environmental health programmes: report of a WHO scientific group.", "content": "Evaluation of environmental health programmes: report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198280"} {"pmid": "4198283", "title": "Microangiopathy in the experimentally diabetic animal.", "content": "Microangiopathy in the experimentally diabetic animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198283"} {"pmid": "4198284", "title": "Microangiopathy in animals with spontaneous diabetes.", "content": "Microangiopathy in animals with spontaneous diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198284"} {"pmid": "4198285", "title": "Pseudo-leukocytosis associated with cryoglobulinemia.", "content": "Pseudo-leukocytosis associated with cryoglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198285"} {"pmid": "4198286", "title": "Immune serum globulin--a cause for anti-Rh (D) passive sensitization.", "content": "Immune serum globulin--a cause for anti-Rh (D) passive sensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198286"} {"pmid": "4198287", "title": "Membrano-proliferative glomerulonephritis associated with persistent viral hepatitis.", "content": "Membrano-proliferative glomerulonephritis associated with persistent viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198287"} {"pmid": "4198289", "title": "\"IGF\" in food allergy?", "content": "\"IGF\" in food allergy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198289"} {"pmid": "4198288", "title": "Mechanisms of drug-enzyme interactions.", "content": "Mechanisms of drug-enzyme interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198288"} {"pmid": "4198293", "title": "Microcirculation of monkey pancreas with special reference to the insulo-acinar portal system. A scanning electron microscope study of vascular casts.", "content": "Microcirculation of monkey pancreas with special reference to the insulo-acinar portal system. A scanning electron microscope study of vascular casts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198293"} {"pmid": "4198295", "title": "Effects of perhexiline maleate in patients with angina pectoris unrelieved by other antianginal agent.", "content": "Effects of perhexiline maleate in patients with angina pectoris unrelieved by other antianginal agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198295"} {"pmid": "4198294", "title": "The effect of trimazosin in essential hypertension.", "content": "The effect of trimazosin in essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198294"} {"pmid": "4198296", "title": "Double-blind clinical evaluation of mazindol, dextroamphetamine, and placebo in treatment of exogenous obesity.", "content": "Double-blind clinical evaluation of mazindol, dextroamphetamine, and placebo in treatment of exogenous obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198296"} {"pmid": "4198298", "title": "Response to a single intravenous dose versus multiple intramuscular administration of iron-dextran complex: a comparative study.", "content": "Response to a single intravenous dose versus multiple intramuscular administration of iron-dextran complex: a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198298"} {"pmid": "4198297", "title": "Oral aminophylline and dikydroxypropyl theophylline in reversible obstructive airway disease: a single-dose, double-blind, crossover comparison.", "content": "Oral aminophylline and dikydroxypropyl theophylline in reversible obstructive airway disease: a single-dose, double-blind, crossover comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198297"} {"pmid": "4198299", "title": "A double-blind comparison of ethoheptazine citrate, propoxyphene hydrochloride, and placebo.", "content": "A double-blind comparison of ethoheptazine citrate, propoxyphene hydrochloride, and placebo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198299"} {"pmid": "4198300", "title": "Clinical trial of a new anti-inflammatory drug in otolaryngology.", "content": "Clinical trial of a new anti-inflammatory drug in otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198300"} {"pmid": "4198301", "title": "Irradiation synovectomy: clinical study of 67 knee effusions intra-articularly irradiated with 90 Y resin.", "content": "Irradiation synovectomy: clinical study of 67 knee effusions intra-articularly irradiated with 90 Y resin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198301"} {"pmid": "4198303", "title": "Influence of treatment on symptomatology and correlated electroencephalographic (EEG) changes in the aged.", "content": "Influence of treatment on symptomatology and correlated electroencephalographic (EEG) changes in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198303"} {"pmid": "4198302", "title": "Treatment of premenopausal endometrial hyperplasia by a combination of a long-acting estrogen and a cyclic progestogen.", "content": "Treatment of premenopausal endometrial hyperplasia by a combination of a long-acting estrogen and a cyclic progestogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198302"} {"pmid": "4198304", "title": "The extrapyramidal neuroleptic syndrome: description and measurement.", "content": "The extrapyramidal neuroleptic syndrome: description and measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198304"} {"pmid": "4198305", "title": "Preanesthetic medication in elective surgery: comparison of intravenous diazepam with meperidine.", "content": "Preanesthetic medication in elective surgery: comparison of intravenous diazepam with meperidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198305"} {"pmid": "4198307", "title": "The use of N-demethyldiazepam in outpatients suffering from insomnia.", "content": "The use of N-demethyldiazepam in outpatients suffering from insomnia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198307"} {"pmid": "4198306", "title": "Clorazepate dipotassium, diazepam and placebo in chronic anxiety.", "content": "Clorazepate dipotassium, diazepam and placebo in chronic anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198306"} {"pmid": "4198308", "title": "Metiapine in acute schizophrenic patients.", "content": "Metiapine in acute schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198308"} {"pmid": "4198309", "title": "Metiapine: the evaluation of the antipsychotic properties of a new neuroleptic. A pilot study.", "content": "Metiapine: the evaluation of the antipsychotic properties of a new neuroleptic. A pilot study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198309"} {"pmid": "4198311", "title": "Comparable therapeutic efficacy of tryptophan and imipramine: average therapeutic ratings versus \"true\" equivalence. An important difference.", "content": "Comparable therapeutic efficacy of tryptophan and imipramine: average therapeutic ratings versus \"true\" equivalence. An important difference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198311"} {"pmid": "4198310", "title": "Potentiation of haloperidol by -methyldopa in the treatment of schizophrenic patients.", "content": "Potentiation of haloperidol by -methyldopa in the treatment of schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198310"} {"pmid": "4198312", "title": "The computer analyzes two psychotherapeutic agents in anxiety-depressed states.", "content": "The computer analyzes two psychotherapeutic agents in anxiety-depressed states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198312"} {"pmid": "4198314", "title": "Effects of molindone on CNS structures: neurophysiological and behavioral correlations.", "content": "Effects of molindone on CNS structures: neurophysiological and behavioral correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198314"} {"pmid": "4198313", "title": "A multicenter investigation of lorazepam in anxiety neurosis.", "content": "A multicenter investigation of lorazepam in anxiety neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198313"} {"pmid": "4198315", "title": "The protein needs of malnourished children.", "content": "The protein needs of malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198315"} {"pmid": "4198316", "title": "Dipropylacetate (Dépakine, Ergenyl) in the treatment of epilepsy.", "content": "Dipropylacetate (Dépakine, Ergenyl) in the treatment of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198316"} {"pmid": "4198317", "title": "Superiority of clonazepam over diazepam in experimental epilepsy.", "content": "Superiority of clonazepam over diazepam in experimental epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198317"} {"pmid": "4198318", "title": "Principles of methodical studies on capillaries in the light of the immunomorphogenesis of the capillary-haemopoietic system. I. Immunobiogenetic studies.", "content": "Principles of methodical studies on capillaries in the light of the immunomorphogenesis of the capillary-haemopoietic system. I. Immunobiogenetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198318"} {"pmid": "4198321", "title": "Pattern formation in the blue-green alga, Anabaena. I. Basic mechanisms.", "content": "Pattern formation in the blue-green alga, Anabaena. I. Basic mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198321"} {"pmid": "4198320", "title": "Intestinal carriage of Klebsiella and pseudomonas in burned children and their comparative role in nosocomial infection.", "content": "Intestinal carriage of Klebsiella and pseudomonas in burned children and their comparative role in nosocomial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198320"} {"pmid": "4198322", "title": "Temperature-sensitive RNA polymerase of a mammalian cell mutant.", "content": "Temperature-sensitive RNA polymerase of a mammalian cell mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198322"} {"pmid": "4198323", "title": "Acetylcholinesterase in human erythroid cells.", "content": "Acetylcholinesterase in human erythroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198323"} {"pmid": "4198324", "title": "Immunogenetic and electrophoretic studies with extracts of different adult Culex pipiens strains.", "content": "Immunogenetic and electrophoretic studies with extracts of different adult Culex pipiens strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198324"} {"pmid": "4198325", "title": "A comparative study of diamine oxidase in amniotic fluid and serum in normal pregnancy and in pregnancy complicated by rhesus iso-immunization.", "content": "A comparative study of diamine oxidase in amniotic fluid and serum in normal pregnancy and in pregnancy complicated by rhesus iso-immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198325"} {"pmid": "4198330", "title": "Premature labour at Groote Schuur Hospital.", "content": "Premature labour at Groote Schuur Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198330"} {"pmid": "4198336", "title": "Dairy herd environment and the control of mastitis.", "content": "Dairy herd environment and the control of mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198336"} {"pmid": "4198339", "title": "Plasma and urine ribonuclease as a measure of nutritional status in children.", "content": "Plasma and urine ribonuclease as a measure of nutritional status in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198339"} {"pmid": "4198340", "title": "Effects of dietary supplementation of monosodium glutamate on infant monkeys, weanling rats, and suckling mice.", "content": "Effects of dietary supplementation of monosodium glutamate on infant monkeys, weanling rats, and suckling mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198340"} {"pmid": "4198341", "title": "Influence of a viral enteric infection on the aminogram and pathology of protein-calorie malnutrition in the pig.", "content": "Influence of a viral enteric infection on the aminogram and pathology of protein-calorie malnutrition in the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198341"} {"pmid": "4198343", "title": "Use of the indirect fluorescent antibody technique in serologic studies of Theileria lawrencei infections in cattle.", "content": "Use of the indirect fluorescent antibody technique in serologic studies of Theileria lawrencei infections in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198343"} {"pmid": "4198342", "title": "International and local growth standards.", "content": "International and local growth standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198342"} {"pmid": "4198344", "title": "Transmissible drug resistance in Enterobacteriaceae isolated from healthy nonhuman primates.", "content": "Transmissible drug resistance in Enterobacteriaceae isolated from healthy nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198344"} {"pmid": "4198345", "title": "Naturally occurring cholelithiasis in a rhesus monkey and its effects on plasma and biliary lipid concentrations.", "content": "Naturally occurring cholelithiasis in a rhesus monkey and its effects on plasma and biliary lipid concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198345"} {"pmid": "4198346", "title": "Characterization of Listeria monocytogenes serotype 5.", "content": "Characterization of Listeria monocytogenes serotype 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198346"} {"pmid": "4198347", "title": "Familial chronic interstitial pneumonia.", "content": "Familial chronic interstitial pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198347"} {"pmid": "4198348", "title": "A new \"double ring\" screening test for alpha1-antitrypsin variants.", "content": "A new \"double ring\" screening test for alpha1-antitrypsin variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198348"} {"pmid": "4198349", "title": "Productivity of prolonged follow-up after chemotherapy for tuberculosis.", "content": "Productivity of prolonged follow-up after chemotherapy for tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198349"} {"pmid": "4198350", "title": "Primary drug-resistant tuberculosis in children, 1961 to 1971. A comparison of the frequency of primary drug-resistant tuberculosis among children observed during the period of transition from long-term to short-term hospitalization of adults with infectious tuberculosis.", "content": "Primary drug-resistant tuberculosis in children, 1961 to 1971. A comparison of the frequency of primary drug-resistant tuberculosis among children observed during the period of transition from long-term to short-term hospitalization of adults with infectious tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198350"} {"pmid": "4198351", "title": "A study of mycobacterial species isolated from patients with chronic respiratory disease.", "content": "A study of mycobacterial species isolated from patients with chronic respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198351"} {"pmid": "4198352", "title": "Scanning electron microscopy of mycobacteria.", "content": "Scanning electron microscopy of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198352"} {"pmid": "4198353", "title": "Effect of age on the fatty acids C14 to C19 of mycobacteria.", "content": "Effect of age on the fatty acids C14 to C19 of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198353"} {"pmid": "4198354", "title": "Species differences in the diurnal rhythmicity of courtship behaviour within the melanogaster group of the genus Drosophila.", "content": "Species differences in the diurnal rhythmicity of courtship behaviour within the melanogaster group of the genus Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198354"} {"pmid": "4198355", "title": "Surgical anatomy of the biliary tract. As demonstrated by peroperative cholangiography.", "content": "Surgical anatomy of the biliary tract. As demonstrated by peroperative cholangiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198355"} {"pmid": "4198356", "title": "The location of N-acetylgalactosamine in the walls of Bacillus subtilis 168.", "content": "The location of N-acetylgalactosamine in the walls of Bacillus subtilis 168. The N-acetylgalactosamine in the walls of Bacillus subtilis 168 occurs in two polymers. One of these contains N-acetylgalactosamine, glucose and phosphorus and is attached to the peptidoglycan through an alkali-labile bond; preliminary studies indicate that a repeating unit of this polymer is glucosyl-N-acetylgalactosamine 1-phosphate. N-Acetylgalactosamine is also associated with the peptidoglycan in a component that is not converted into the free sugar or other soluble compounds on treatment of the walls with alkali. The two polymers containing N-acetylgalactosamine are released on autolysis of the walls and can be separated by ion-exchange chromatography. As glucose 6-phosphate is produced by gentle hydrolysis of the wall with acid a third phosphate polymer, poly(glucose 1-phosphate), may occur in this wall. However, as no polymer with this structure could be separated from that containing galactosamine, its existence has not been established unequivocally. The methods described permit the study of variations in N-acetylgalactosamine content with respect to growth conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198356"} {"pmid": "4198357", "title": "Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae.", "content": "Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae. 1. The concentrations of folate derivatives in aerobic cultures of Saccharomyces cerevisiae (A.T.C.C. 9763) were determined by microbiological assay employing Lactobacillus casei (A.T.C.C. 7469) and Pediococcus cerevisiae (A.T.C.C. 8081). Cells cultured in media lacking l-methionine contained higher concentrations of folate derivatives than cells grown in the same media supplemented with 2.5mumol of l-methionine/ml. The concentrations of highly conjugated derivatives were also decreased by supplementing the growth medium with l-methionine. 2. DEAE-cellulose column chromatography of extracts prepared from cells grown under these conditions revealed that the concentrations of methylated tetrahydrofolates were drastically decreased by the methionine supplement. Smaller decreases were also observed in the concentrations of formylated and unsubstituted derivatives. 3. The concentrations of four enzymes of C(1) metabolism were compared after 6h of growth in the presence and in the absence of l-methionine (2.5mumol/ml). The specific activities of formyltetrahydrofolate synthetase, methylenetetrahydrofolate reductase and serine hydroxymethyltransferase were not altered by this treatment but that of 5-methyltetrahydrofolate-homocysteine methyltransferase was decreased by approx. 65% when l-methionine was supplied. The activities of 5-methyltetrahydrofolate-homocysteine methyltransferase, serine hydroxymethyltransferase and formyltetrahydrofolate synthetase were not appreciably altered by l-methionine in vitro. In contrast this amino acid was found to inhibit the activity of methylenetetrahydrofolate reductase. 4. Feeding experiments employing sodium [(14)C]formate indicated that cells grown in the presence of exogenous methionine, although having less ability to convert formate into methionine, readily incorporated (14)C into serine and the adenosyl moiety of S-adenosylmethionine. 5. It is suggested that exogenous l-methionine controls C(1) metabolism in Saccharomyces principally by regulation of methyl-group biogenesis within the folate pool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198357"} {"pmid": "4198359", "title": "A possible ribosomal-directed regulatory system in Euglena gracilis. Carbon dioxide fixation.", "content": "A possible ribosomal-directed regulatory system in Euglena gracilis. Carbon dioxide fixation. It was shown that cycloheximide inhibits CO(2) fixation in Euglena cells in the dark, but no effect of chloramphenicol was found. The light-dependent CO(2) fixation was inhibited by chloramphenicol and by large amounts of cycloheximide, but was stimulated by small amounts of cycloheximide. The presence of the stimulatory concentration of cycloheximide abolished the inhibition effect of high concentrations of chloramphenicol. The results indicate that the light-dependent CO(2) fixation is controlled by a repression-derepression regulatory system, which seems to be independent of chlorophyll synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198359"} {"pmid": "4198358", "title": "A possible ribosomal-directed regulatory system in Euglena gracilis. Chlorophyll synthesis.", "content": "A possible ribosomal-directed regulatory system in Euglena gracilis. Chlorophyll synthesis. Cycloheximide at concentrations of 0.1-100mum stimulated chlorophyll synthesis when dark-grown cells of Euglena were illuminated. Chloramphenicol (1-4mm) inhibited chlorophyll synthesis. The effect of cycloheximide on the incorporation of [(14)C]leucine into material insoluble in trichloroacetic acid, and its failure to affect the incorporation of [(32)P]orthophosphate into such material in short incubations, are interpreted as evidence that cycloheximide specifically inhibits protein synthesis by 80S ribosomes. Since the inhibitory effect of chloramphenicol on chlorophyll synthesis is counteracted by the presence of cycloheximide, it is suggested that chlorophyll synthesis is subject to control by a cytoplasmic repressor synthesized on 80S ribosomes, and to a de-repressor synthesized on 70S ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198358"} {"pmid": "4198360", "title": "Kinetics of the diamine oxidase reaction.", "content": "Kinetics of the diamine oxidase reaction. 1. The oxidation of p-dimethylaminomethylbenzylamine was followed spectrophotometrically by measuring the change in E(250) caused by the p-dimethylaminomethylbenzaldehyde produced under a wide variety of experimental conditions. 2. The effect of variations in concentrations of both substrates (amine and oxygen) and all products (aminoaldehyde, hydrogen peroxide and ammonia) on this reaction was studied and the results used to develop a formal mechanism. 3. The nature of the rate-limiting step was elucidated by studying the effects of alterations in ionic strength, dielectric constant and deuterium substitution on the velocity of the forward reaction. 4. Thermodynamic activation energy parameters were obtained at several pH values from the effects of temperature on the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198360"} {"pmid": "4198361", "title": "Selective extraction of polymers from cell walls of gram-positive bacteria.", "content": "Selective extraction of polymers from cell walls of gram-positive bacteria. Brief heating of Bacillus Licheniformis cell walls at 100 degrees C in aqueous buffers of pH3.0-4.0 removes some polymers but not others from the mucopeptides. For example, relatively undegraded teichuronic acid can be extracted at 100 degrees C in 20min at pH3.0 whereas the teichoic acids are not removed. Similar specificity can be shown with walls from three other species of micro-organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198361"} {"pmid": "4198362", "title": "Comparative study of the optical rotatory dispersion and circular dichroism of human erythrocyte carbonic anhydrases A and B, and conformational variants B1 and B2.", "content": "Comparative study of the optical rotatory dispersion and circular dichroism of human erythrocyte carbonic anhydrases A and B, and conformational variants B1 and B2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198362"} {"pmid": "4198363", "title": "Metabolic studies of (75Se)selenomethionine and (75Se)selenite in the rat.", "content": "Metabolic studies of (75Se)selenomethionine and (75Se)selenite in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198363"} {"pmid": "4198364", "title": "Protein requirements of growing lambs.", "content": "Protein requirements of growing lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198364"} {"pmid": "4198365", "title": "A device and technique for urethrography in the female.", "content": "A device and technique for urethrography in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198365"} {"pmid": "4198366", "title": "Osteoporosis and long-term corticosteroid therapy.", "content": "Osteoporosis and long-term corticosteroid therapy. Sequential measurements of total body calcium by in-vivo neutron activation analysis were made in five patients treated with corticosteroid drugs for severe inflammatory disease. No evidence of osteoporosis was seen to develop during the course of 20-33 months of study. In one case a substantial rise in total body calcium was found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198366"} {"pmid": "4198367", "title": "Significance of hyperamylasaemia and abdominal pain in diabetic ketoacidosis.", "content": "Significance of hyperamylasaemia and abdominal pain in diabetic ketoacidosis. An analysis of 35 consecutive episodes of diabetic ketoacidosis confirmed the frequent high levels of serum amylase in this condition. Serum amylase was raised during 21 episodes (60%), and in six instances (17%) the peak level exceeded 1,000 Somogyi units per 100 ml. Hyperamylasaemia was more often found when the initial blood sugar exceeded 500 mg/100 ml, or when the onset of the episode had been relatively acute (less than 48 hours). There was no conclusive evidence in any patient to support a diagnosis of acute pancreatitis and other explanations for the hyperamylasaemia are discussed. Even grossly raised amylase levels were not associated with increased mortality or morbidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198367"} {"pmid": "4198368", "title": "Drugs for angina pectoris.", "content": "Drugs for angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198368"} {"pmid": "4198369", "title": "Retrograde transneuronal degeneration of optic fibers and their terminals in lateral geniculate nucleus of rhesus monkey.", "content": "Retrograde transneuronal degeneration of optic fibers and their terminals in lateral geniculate nucleus of rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198369"} {"pmid": "4198370", "title": "Optic chiasm section affects discriminability of asymmetric patterns by monkeys.", "content": "Optic chiasm section affects discriminability of asymmetric patterns by monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198370"} {"pmid": "4198384", "title": "Haptenic activity of L-phenylalanine mustard.", "content": "Haptenic activity of L-phenylalanine mustard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198384"} {"pmid": "4198383", "title": "Xenotransplantation of established human endometrial cells into newborn hamsters.", "content": "Xenotransplantation of established human endometrial cells into newborn hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198383"} {"pmid": "4198385", "title": "Clinical laboratory use of differential light scattering. I. Antibiotic susceptibility testing.", "content": "Clinical laboratory use of differential light scattering. I. Antibiotic susceptibility testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198385"} {"pmid": "4198386", "title": "Uptake of protein in swallowed amniotic fluid by monkey fetal intestine in utero.", "content": "Uptake of protein in swallowed amniotic fluid by monkey fetal intestine in utero.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198386"} {"pmid": "4198388", "title": "Bacteriological evaluations of swine exposed to lethal levels of gamma radiation.", "content": "Bacteriological evaluations of swine exposed to lethal levels of gamma radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198388"} {"pmid": "4198389", "title": "Chelated trace minerals for G-F swine.", "content": "Chelated trace minerals for G-F swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198389"} {"pmid": "4198390", "title": "Physico-chemical characteristics and regional distribution studies of GP-350, a soluble sialoglycoprotein from brain.", "content": "Physico-chemical characteristics and regional distribution studies of GP-350, a soluble sialoglycoprotein from brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198390"} {"pmid": "4198391", "title": "Immunochemical studies on glutamic acid decarboxylase (EC 4.1.1.15) from mouse brain.", "content": "Immunochemical studies on glutamic acid decarboxylase (EC 4.1.1.15) from mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198391"} {"pmid": "4198392", "title": "The effects of changes in arterial plasma calcium concentration on submandibular secretory potentials.", "content": "The effects of changes in arterial plasma calcium concentration on submandibular secretory potentials. 1. The concentration of Ca in the arterial blood plasma perfusing submandibular glands of anaesthetized cats and possums (Trichosurus vulpecula) was altered by constant-rate close arterial injection of isotonic CaCl(2) or EDTA solutions.2. There were no significant changes in the resting potentials of surface acinar cells in either species when the arterial plasma Ca concentration was altered over the range 0-30 mM.3. Secretory potentials in response to parasympathetic stimuli and close arterial injection of ACh were reduced and finally abolished during EDTA injection, but temporarily restored by injection of CaCl(2).4. Secretory potentials in response to 1 Hz parasympathetic stimuli in the cat were enhanced by increasing the gland arterial Ca concentration up to 5 mM; but responses to 10 Hz stimuli or close arterial ACh injection were not affected. There was no such enhancement of secretory potentials in the possum.5. Increase in the gland arterial plasma Ca concentration above 5 mM caused reduction in the amplitudes of the secretory potentials to all stimuli in both species, until they were abolished at 7-10 mM in the possum and 15-20 mM in the cat.6. In both species, increase in the gland arterial plasma Ca concentration caused increase in the gland blood flow and enhancement of the vasodilator effects of parasympathetic stimuli and ACh injection. EDTA injection was sometimes associated with a vasoconstrictor response to parasympathetic stimuli.7. It is concluded that the secretory potentials, but not the resting potentials, of submandibular secretory cells require the presence of Ca in the interstitial fluid. It is suggested that Ca affects both the release of transmitter and at higher concentration the mechanism by which it activates the secretory cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198392"} {"pmid": "4198393", "title": "Functional studies of splenic and internal mammary artery implants in canine hearts.", "content": "Functional studies of splenic and internal mammary artery implants in canine hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198393"} {"pmid": "4198432", "title": "Treatment for hypertension.", "content": "Treatment for hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198432"} {"pmid": "4198433", "title": "Quantitative uptake measurements with a shadow shield whole-body counter.", "content": "Quantitative uptake measurements with a shadow shield whole-body counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198433"} {"pmid": "4198434", "title": "Intrinsic dwarfism presenting at birth. Preliminary communication on nomenclature.", "content": "Intrinsic dwarfism presenting at birth. Preliminary communication on nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198434"} {"pmid": "4198435", "title": "Comparison of carbenicillin and penicillin in the treatment of uncomplicated gonorrhea.", "content": "Comparison of carbenicillin and penicillin in the treatment of uncomplicated gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198435"} {"pmid": "4198436", "title": "Current concepts in therapy: general concepts in the use of antibiotics in adults.", "content": "Current concepts in therapy: general concepts in the use of antibiotics in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198436"} {"pmid": "4198441", "title": "Abortion associated with Brucella abortus (Biotype 1) in the T.B. mare.", "content": "Abortion associated with Brucella abortus (Biotype 1) in the T.B. mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198441"} {"pmid": "4198438", "title": "Autoimmune hemolytic anemia caused by anti-D.", "content": "Autoimmune hemolytic anemia caused by anti-D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198438"} {"pmid": "4198439", "title": "Post-Konyne hepatitis: the ineffectiveness of screening for the hepatitis B antigen (HBAg).", "content": "Post-Konyne hepatitis: the ineffectiveness of screening for the hepatitis B antigen (HBAg).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198439"} {"pmid": "4198437", "title": "Nonspecific warm hemolysins of papain-treated cells: serologic characterization and transfusion risk.", "content": "Nonspecific warm hemolysins of papain-treated cells: serologic characterization and transfusion risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198437"} {"pmid": "4198440", "title": "Another pitfall in blood group testing for nonpaternity.", "content": "Another pitfall in blood group testing for nonpaternity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198440"} {"pmid": "4198448", "title": "Interrelations between diagnostic criteria of the iron status and 50-mg ferrous iron absorption in iron-replete and iron-deficient subjects.", "content": "Interrelations between diagnostic criteria of the iron status and 50-mg ferrous iron absorption in iron-replete and iron-deficient subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198448"} {"pmid": "4198449", "title": "The histochemistry of fibrinolysis in haemophilic synovial membranes.", "content": "The histochemistry of fibrinolysis in haemophilic synovial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198449"} {"pmid": "4198450", "title": "Ready release of intracellular muramidase (lysozyme) from mononuclear cells in the skin window exudates.", "content": "Ready release of intracellular muramidase (lysozyme) from mononuclear cells in the skin window exudates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198450"} {"pmid": "4198452", "title": "Myeloma in mother and daughter.", "content": "Myeloma in mother and daughter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198452"} {"pmid": "4198451", "title": "Recombination experiments with an unusual L-chain related myeloma protein.", "content": "Recombination experiments with an unusual L-chain related myeloma protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198451"} {"pmid": "4198453", "title": "Myelofibrosis, osteolytic bone lesions and hypercalcemia in chronic myeloid leukemia.", "content": "Myelofibrosis, osteolytic bone lesions and hypercalcemia in chronic myeloid leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198453"} {"pmid": "4198454", "title": "Nitroglycerin and coronary blood flow in coronary artery disease.", "content": "Nitroglycerin and coronary blood flow in coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198454"} {"pmid": "4198455", "title": "Use of parenteral nutrition in treatment of advanced regional enteritis.", "content": "Use of parenteral nutrition in treatment of advanced regional enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198455"} {"pmid": "4198456", "title": "Paresthesias and hypophosphatemia occurring with parenteral alimentation.", "content": "Paresthesias and hypophosphatemia occurring with parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198456"} {"pmid": "4198457", "title": "Hormone and enzyme levels in normal and complicated pregnancy.", "content": "Hormone and enzyme levels in normal and complicated pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198457"} {"pmid": "4198458", "title": "Localization of human chorionic gonadotropic and somatomammotropic hormones by the peroxidase immunohistoenzymologic method in villi and amniotic epithelium of human placentas (from six weeks to term).", "content": "Localization of human chorionic gonadotropic and somatomammotropic hormones by the peroxidase immunohistoenzymologic method in villi and amniotic epithelium of human placentas (from six weeks to term).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198458"} {"pmid": "4198459", "title": "Scrub typhus in South Vietnam. A study of 87 cases.", "content": "Scrub typhus in South Vietnam. A study of 87 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198459"} {"pmid": "4198462", "title": "Respiratory abnormalities in workers exposed to grain dust.", "content": "Respiratory abnormalities in workers exposed to grain dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198462"} {"pmid": "4198463", "title": "Chronic exposure to nitrogen dioxide.", "content": "Chronic exposure to nitrogen dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198463"} {"pmid": "4198464", "title": "Pressure effect on ERG and optic nerve conduction of visual impulse. Short-term effects in owl monkeys.", "content": "Pressure effect on ERG and optic nerve conduction of visual impulse. Short-term effects in owl monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198464"} {"pmid": "4198465", "title": "Unusual intranuclear tubular structures associated with the maturation of Herpesvirus saimiri in monkey kidney cell cultures.", "content": "Unusual intranuclear tubular structures associated with the maturation of Herpesvirus saimiri in monkey kidney cell cultures. Unusual intranuclear tubules have been observed in cultures of both African green monkey and owl monkey kidney cells infected with Herpesvirus saimiri; the material was studied in thin sections with the electron microscope. The tubules were seen in about 10% of virus-containing cells at the stage when the virus matured by budding at the nuclear membrane, measured 160-180 nm in diameter and up to 3.6 μm in length, were bounded by an outer \"membrane\" and contained beneath this an electron dense repeating structure arranged either as a coil or a series of evenly spaced rings. The morphology and significance of the tubules are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198465"} {"pmid": "4198466", "title": "Kinetics of entry and distribution of 5-fluorouracil in cerebrospinal fluid and brain following intravenous injection in a primate.", "content": "Kinetics of entry and distribution of 5-fluorouracil in cerebrospinal fluid and brain following intravenous injection in a primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198466"} {"pmid": "4198467", "title": "Increase of soluble RNA methylase activities by chemical carcinogens.", "content": "Increase of soluble RNA methylase activities by chemical carcinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198467"} {"pmid": "4198468", "title": "Immunological progress in bilharziasis.", "content": "Immunological progress in bilharziasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198468"} {"pmid": "4198460", "title": "The translabyrinthine removal of acoustic and other cerebellopontine angle tumors.", "content": "The translabyrinthine removal of acoustic and other cerebellopontine angle tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198460"} {"pmid": "4198461", "title": "Electrical stimulation of the inner ear.", "content": "Electrical stimulation of the inner ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198461"} {"pmid": "4198470", "title": "Infective endocarditis in drug addicts. Experiences with medical and surgical treatment.", "content": "Infective endocarditis in drug addicts. Experiences with medical and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198470"} {"pmid": "4198469", "title": "Evaluation of hollow fiber and spiral coil membrane oxygenators designed for cardiopulmonary bypass in infants.", "content": "Evaluation of hollow fiber and spiral coil membrane oxygenators designed for cardiopulmonary bypass in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198469"} {"pmid": "4198471", "title": "Studies of the distribution of a new avian pancreatic polypeptide and insulin among birds, reptiles, amphibians and mammals.", "content": "Studies of the distribution of a new avian pancreatic polypeptide and insulin among birds, reptiles, amphibians and mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198471"} {"pmid": "4198472", "title": "Morphological and functional evidence for corpus luteum activity during late pregnancy in the rhesus monkey.", "content": "Morphological and functional evidence for corpus luteum activity during late pregnancy in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198472"} {"pmid": "4198473", "title": "The biological response of infant nonhuman primates to a polychlorinated biphenyl.", "content": "The biological response of infant nonhuman primates to a polychlorinated biphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198473"} {"pmid": "4198474", "title": "Toxicity of metabolites produced by the \"Alternaria\".", "content": "Toxicity of metabolites produced by the \"Alternaria\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198474"} {"pmid": "4198475", "title": "Protein calorie malnutrition in early childhood.", "content": "Protein calorie malnutrition in early childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198475"} {"pmid": "4198478", "title": "Diseases from pets.", "content": "Diseases from pets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198478"} {"pmid": "4198479", "title": "Contributions of army medicine to civilian medicine.", "content": "Contributions of army medicine to civilian medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198479"} {"pmid": "4198476", "title": "Red cell density in various blood disorders.", "content": "Red cell density in various blood disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198476"} {"pmid": "4198480", "title": "A study of malaria rates in the Que Son Mountains of Vietnam.", "content": "A study of malaria rates in the Que Son Mountains of Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198480"} {"pmid": "4198481", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198481"} {"pmid": "4198482", "title": "Prophylaxis of malaria in man using the sulfone DFD with pyrimethamine.", "content": "Prophylaxis of malaria in man using the sulfone DFD with pyrimethamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198482"} {"pmid": "4198483", "title": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamà and Colombia. IV. Arbovirus surveillance in man.", "content": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamà and Colombia. IV. Arbovirus surveillance in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198483"} {"pmid": "4198484", "title": "Tuberculosis in active duty military personnel.", "content": "Tuberculosis in active duty military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198484"} {"pmid": "4198485", "title": "Clinical decisions and outcomes in a navy psychiatric service.", "content": "Clinical decisions and outcomes in a navy psychiatric service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198485"} {"pmid": "4198486", "title": "The military pediatric experience as training.", "content": "The military pediatric experience as training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198486"} {"pmid": "4198487", "title": "In vitro thyroid function tests: a comparison of some commercially available kits.", "content": "In vitro thyroid function tests: a comparison of some commercially available kits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198487"} {"pmid": "4198488", "title": "Gonorrhea in a military prenatal population.", "content": "Gonorrhea in a military prenatal population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198488"} {"pmid": "4198489", "title": "Beta-hemolytic streptococcus in a population of antepartum patients.", "content": "Beta-hemolytic streptococcus in a population of antepartum patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198489"} {"pmid": "4198493", "title": "Lennox's syndrome and lead intoxication.", "content": "Lennox's syndrome and lead intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198493"} {"pmid": "4198494", "title": "Gonococcal arthritis in a newborn infant.", "content": "Gonococcal arthritis in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198494"} {"pmid": "4198495", "title": "Gonococcal tonsillitis-pharyngitis in a 5-year-old girl.", "content": "Gonococcal tonsillitis-pharyngitis in a 5-year-old girl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198495"} {"pmid": "4198496", "title": "Pesticides in soil: organochlorine pesticide residues in soils and crops of the Corn Belt region, United States--1970.", "content": "Pesticides in soil: organochlorine pesticide residues in soils and crops of the Corn Belt region, United States--1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198496"} {"pmid": "4198498", "title": "An interracial study in the management of infants and children with convulsions.", "content": "An interracial study in the management of infants and children with convulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198498"} {"pmid": "4198499", "title": "A technique for chronic subclavian vein catheterization.", "content": "A technique for chronic subclavian vein catheterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198499"} {"pmid": "4198500", "title": "Pesticide residues in food.", "content": "Pesticide residues in food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198500"} {"pmid": "4198503", "title": "Aggression within social groups of rhesus monkeys (Macaca mulatta): effect of contact between groups.", "content": "Aggression within social groups of rhesus monkeys (Macaca mulatta): effect of contact between groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198503"} {"pmid": "4198504", "title": "Monkeys (Macaca mulatta) raised only with peers. A pilot study.", "content": "Monkeys (Macaca mulatta) raised only with peers. A pilot study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198504"} {"pmid": "4198505", "title": "Courtship processing in Drosophila melanogaster. I. Selection for receptivity to wingless males.", "content": "Courtship processing in Drosophila melanogaster. I. Selection for receptivity to wingless males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198505"} {"pmid": "4198506", "title": "Courtship processing in Drosophila melanogaster. II. An adaptation to selection for receptivity to wingless males.", "content": "Courtship processing in Drosophila melanogaster. II. An adaptation to selection for receptivity to wingless males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198506"} {"pmid": "4198508", "title": "Australia antigen in Zaïre. Studies on leprosy.", "content": "Australia antigen in Zaïre. Studies on leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198508"} {"pmid": "4198511", "title": "Additional phage-typing scheme for C. diphtheriae.", "content": "Additional phage-typing scheme for C. diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198511"} {"pmid": "4198515", "title": "A lattice structure in water-swollen liver mitochondria.", "content": "A lattice structure in water-swollen liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198515"} {"pmid": "4198516", "title": "Iodoacetamide-induced sensitization of the pancreatic beta-cells to glucose stimulation.", "content": "Iodoacetamide-induced sensitization of the pancreatic beta-cells to glucose stimulation. At a glucose concentration of 3mm or less, iodoacetamide had no effect on the release of insulin from microdissected pancreatic islets of ob/ob-mice. At higher glucose concentrations, iodoacetamide exerted both an initial stimulatory and a subsequent inhibitory action. When islets were perifused with 1mm-iodoacetamide and 17mm-glucose the inhibitory action predominated after about 15min of transient stimulation. With decreasing concentrations of iodoacetamide the stimulatory phase was gradually prolonged, and with 0.003-0.1mm-iodoacetamide stimulation only was observed for 75min. Prolonged stimulation was also noted after a short pulse of iodoacetamide. Similar responses to 0.1mm-iodoacetamide were observed with islets from normal mice. With islets from ob/ob-mice the effect of 0.1mm-iodoacetamide was reproduced with 0.1mm-iodoacetate, whereas 0.1mm-acetamide had no apparent effect. Iodoacetamide increased the V(max.) of glucose-stimulated insulin release without altering the apparent K(m) for glucose. Leucine, glibenclamide or theophylline could not replace glucose in this synergistic action with iodoacetamide. Iodoacetamide rather inhibited the insulin-releasing action of theophylline. Iodoacetamide-induced potentiation of the glucose-stimulated insulin release was rapidly and reversibly inhibited by mannoheptulose, adrenaline, or calcium deficiency. The potentiating effect on insulin release was not paralleled by effects on glucose oxidation or on islet fructose 1,6-diphosphate. However, the inhibitory action of iodoacetamide might be explained by inhibition of glycolysis as evidenced by an inhibition of glucose oxidation and a rise of fructose 1,6-diphosphate. The results support our previous hypothesis that thiol reagents can stimulate insulin release by acting on relatively superficial thiol groups in the beta-cell plasma membrane. Glycolysis seems to be necessary in order for iodoacetamide to stimulate in this way.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198516"} {"pmid": "4198518", "title": "Bioavailability of peroral dosage forms.", "content": "Bioavailability of peroral dosage forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198518"} {"pmid": "4198517", "title": "The purification and properties of extracellular glycosidases of the cellular slime mould Dictyostelium discoideum.", "content": "The purification and properties of extracellular glycosidases of the cellular slime mould Dictyostelium discoideum. The purification of beta-N-acetylhexosaminidase, alpha-glucosidase, alpha-mannosidase and beta-glucosidase from the spent growth medium of Dictyostelium discoideum strain Ax-2 myxamoebae is described. beta-N-Acetylhexosaminidase and alpha-glucosidase were obtained in high yield and as homogeneous preparations whereas the alpha-mannosidase preparation consisted of two electrophoretically distinct isoenzymes. The physical, chemical and kinetic properties of these enzymes are described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198517"} {"pmid": "4198522", "title": "Anatomical differences between the neocortex of man and other primates.", "content": "Anatomical differences between the neocortex of man and other primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198522"} {"pmid": "4198523", "title": "Centrifugal fibers to the retina in the rhesus monkey.", "content": "Centrifugal fibers to the retina in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198523"} {"pmid": "4198529", "title": "Enteral hyperalimentation with elemental diet.", "content": "Enteral hyperalimentation with elemental diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198529"} {"pmid": "4198528", "title": "Local metabolic changes in spinal cord injury.", "content": "Local metabolic changes in spinal cord injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198528"} {"pmid": "4198532", "title": "Double-antibody solid-phase radioimmunoassays for gonadotropins in serum.", "content": "Double-antibody solid-phase radioimmunoassays for gonadotropins in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198532"} {"pmid": "4198533", "title": "TRF test in patients with hypothalamic-pituitary disorders.", "content": "TRF test in patients with hypothalamic-pituitary disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198533"} {"pmid": "4198535", "title": "Resynthesis of chick blastodermic cells following dissociation.", "content": "Resynthesis of chick blastodermic cells following dissociation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198535"} {"pmid": "4198534", "title": "The jejunal mucosa in protein-energy malnutrition. A clinical, histological, and ultrastructural study.", "content": "The jejunal mucosa in protein-energy malnutrition. A clinical, histological, and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198534"} {"pmid": "4198526", "title": "Studies of the use of tumor vaccine for the cancer patient.", "content": "Studies of the use of tumor vaccine for the cancer patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198526"} {"pmid": "4198543", "title": "Production of anti phenobarbital antibody in rabbits by immunization with p-azophenobarbital acetylated bovine serum albumin.", "content": "Production of anti phenobarbital antibody in rabbits by immunization with p-azophenobarbital acetylated bovine serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198543"} {"pmid": "4198527", "title": "Pathophysiology of shock secondary to underwater decompression sickness.", "content": "Pathophysiology of shock secondary to underwater decompression sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198527"} {"pmid": "4198544", "title": "Circular dichroism studies on protohemoproteins. 3. cytochrome b5 from rabbit liver microsomes, and cytochrome b-557.5 from Rhodospirillum rubrum.", "content": "Circular dichroism studies on protohemoproteins. 3. cytochrome b5 from rabbit liver microsomes, and cytochrome b-557.5 from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198544"} {"pmid": "4198545", "title": "The naso-temporal division of the monkey's retina.", "content": "The naso-temporal division of the monkey's retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198545"} {"pmid": "4198546", "title": "Pseudomonas pneumonia.", "content": "Pseudomonas pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198546"} {"pmid": "4198547", "title": "A new small diameter mass spectrometer cannula for medical use.", "content": "A new small diameter mass spectrometer cannula for medical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198547"} {"pmid": "4198548", "title": "Intermediate care for the aged: accommodation requirements and economic considerations.", "content": "Intermediate care for the aged: accommodation requirements and economic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198548"} {"pmid": "4198551", "title": "Urinary tract infection and secretory urinary IgA in malnutrition.", "content": "Urinary tract infection and secretory urinary IgA in malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198551"} {"pmid": "4198552", "title": "Some observations on pelvic floor evolution in primates.", "content": "Some observations on pelvic floor evolution in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198552"} {"pmid": "4198553", "title": "Absence of nerve growth factor in the venoms of bees, scorpions, spiders and toads.", "content": "Absence of nerve growth factor in the venoms of bees, scorpions, spiders and toads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198553"} {"pmid": "4198557", "title": "Waldenström's macroglobulinaemia with xanthomatosis and hypercholesterolaemia. Report of a case.", "content": "Waldenström's macroglobulinaemia with xanthomatosis and hypercholesterolaemia. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198557"} {"pmid": "4198559", "title": "The strategy of identification of mycobacteria in a regional reference laboratory.", "content": "The strategy of identification of mycobacteria in a regional reference laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198559"} {"pmid": "4198561", "title": "Identification of mycobacteria as a clinical service.", "content": "Identification of mycobacteria as a clinical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198561"} {"pmid": "4198563", "title": "Pathogenicity as the main differentiating character within the avium-intracellulare complex.", "content": "Pathogenicity as the main differentiating character within the avium-intracellulare complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198563"} {"pmid": "4198565", "title": "Study of mycobacteria strains belonging to the avian-intracellular group isolated from monkeys.", "content": "Study of mycobacteria strains belonging to the avian-intracellular group isolated from monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198565"} {"pmid": "4198566", "title": "Immunodiffusion analysis--a rational basis for the taxonomy of mycobacteria.", "content": "Immunodiffusion analysis--a rational basis for the taxonomy of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198566"} {"pmid": "4198564", "title": "Fractionation and purification of the antigenic material for immunogenic studies of atypical mycobacteria.", "content": "Fractionation and purification of the antigenic material for immunogenic studies of atypical mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198564"} {"pmid": "4198567", "title": "Thin-layer chromatography of mycobacterial lipids as an aid to classification.", "content": "Thin-layer chromatography of mycobacterial lipids as an aid to classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198567"} {"pmid": "4198568", "title": "Intra-specific variation in the mycobacteria. A taxonomic aid.", "content": "Intra-specific variation in the mycobacteria. A taxonomic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198568"} {"pmid": "4198580", "title": "Ectopic bone formation in patients with spinal cord injury.", "content": "Ectopic bone formation in patients with spinal cord injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198580"} {"pmid": "4198582", "title": "Some properties of the uridine diphosphate glucuronyltransferase activity synthesizing thio-beta-D-glucuronides.", "content": "Some properties of the uridine diphosphate glucuronyltransferase activity synthesizing thio-beta-D-glucuronides. 1. Some properties of the UDP-glucuronyltransferase synthesizing thio-beta-d-glucuronides were investigated and compared with those of the enzyme synthesizing the O-glucuronides of analogous phenols. 2. Enzyme activity was generally similar for both classes of substrate in tissue distribution, intracellular location, optimum pH, perinatal development and induction by organ culture or by phenobarbital. 3. Certain differences were noted between the two types of activity in behaviour on storage and on activation, in kinetic behaviour and in distribution between Wistar and Gunn rats; the Gunn rats were not deficient in hepatic UDP-glucuronyltransferase activity towards o-aminothiophenol. 4. These differences are no greater than those exhibited in the synthesis of various O-glucuronides; therefore thiolic substrates could compete in vivo with phenolic compounds for access to the UDP-glucuronyltransferase complex as well as for UDP-glucuronic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198582"} {"pmid": "4198583", "title": "The characterization of C-phycocyanin from an extremely halo-tolerant blue-green alga, Coccochloris elabens.", "content": "The characterization of C-phycocyanin from an extremely halo-tolerant blue-green alga, Coccochloris elabens. C-Phycocyanin was isolated and purified from a uni-algal culture of an extremely halo-tolerant blue-green alga, Coccochloris elabens. This alga can be grown under laboratory conditions in 25% (w/v) NaCl. Purified halophile phycocyanin was characterized by amino acid analysis and the measurement of sedimentation velocity, fluorescence polarization and immunodiffusion as a function of protein concentration, pH and ionic strength. The results were compared with those of studies of phycocyanin isolated from Plectonema calothricoides and from several other sources. The states of aggregation previously characterized as being present in other C-phycocyanins, monomer, trimer and hexamer, were present in halophile phycocyanin and were characterized as antigenically related to all C-phycocyanins tested. The equilibrium between 3S monomer and 11S hexamer at low concentrations in halophile phycocyanin was quantitatively similar to that for other phycocyanins. The effect of pH and ionic strength on the 6S (trimer) and 11S (hexamer) aggregation of halophile phycocyanin was markedly salt-dependent and the relative amount of each aggregate in the presence of 2m-NaCl was like that of C-phycocyanin from mesophiles, in the absence of additional salt. In antigenic relationship and aggregation properties, the phycocyanin from C. elabens appeared to be most closely related to that isolated from the thermophilic blue-green alga, Synechococcus lividus. Amino acid content of the halophile phycocyanin indicated the presence of a significantly larger number of acidic residues than that found in mesophiles. Explanations of the properties of the halophile protein require consideration of a strong contribution of hydrophobic forces and utilize both charge-shielding and salting-out effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198583"} {"pmid": "4198584", "title": "The organ-specificity of ferritin in human and horse liver and spleen.", "content": "The organ-specificity of ferritin in human and horse liver and spleen. 1. Ferritin was isolated from human and horse spleen and liver, and apoferritin prepared therefrom. 2. The electrophoretic mobilities of the four apoferritins were determined on polyacrylamide gels and on cellulose acetate strips, and all found to be equal. 3. Homologous ferritins share reactions of identity in immunodiffusion experiments, whereas heterologous ferritins show only partial identity. 4. The subunit molecular weight of each of the apoferritins was determined by polyacrylamide-gel electrophoresis in sodium dodecyl sulphate and by chromatography on agarose columns in 6m-guanidine-HCl. A value of approx. 18500 was found in all cases. The proteins all had sedimentation coefficients of 17-18S. It thus seems that they have identical quaternary structures. 5. The amino acid compositions of the proteins revealed distinct differences both between organs and between species. This was confirmed by analysis of the tryptic peptide patterns, where it was found that about one-third of the peptides were common to the four proteins and the other two-thirds varied from protein to protein. 6. It is concluded that the apoferritins present in the liver and spleen of human and horse are both organ- and species-specific. 7. The apoferritin isolated from the liver of a patient with idiopathic haemochromatosis was identical with normal human liver apoferritin by the criteria described above.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198584"} {"pmid": "4198585", "title": "Immunological properties of N-acetyl-beta-D-glucosaminidase of normal human liver and of GM2-gangliosidosis liver.", "content": "Immunological properties of N-acetyl-beta-D-glucosaminidase of normal human liver and of GM2-gangliosidosis liver. Antisera were raised to a partially purified preparation of human liver hexosaminidase and to highly purified preparations of hexosaminidase isoenzymes A and B. All the antisera precipitated the enzyme in an enzymically active form, which could be located on immunodiffusion and immunoelectrophoretic gels by using a histochemical substrate. The antisera to the purified isoenzymes were shown to react with hexosaminidase from human liver, kidney, brain and spleen, but did not cross-react with human liver beta-glucosidase, beta-galactosidase, alpha-mannosidase, beta-xylosidase, arylsulphatase or acid phosphatase. Hexosaminidases A and B were immunologically identical. The immunological properties of the hexosaminidases from livers of patients with three types of GM(2)-gangliosidoses were closely similar. No evidence could be found for cross-reacting material in enzyme-deficient states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198585"} {"pmid": "4198587", "title": "The inhibitory effect of manganese on transmitter release at the neuromuscular junction of the toad.", "content": "The inhibitory effect of manganese on transmitter release at the neuromuscular junction of the toad. 1. Manganese, at low concentrations (0.5-2.0 mM), blocks neuromuscular transmission in toads. Endplate potentials (e.p.ps) are reduced in amplitude but the amplitude of miniature endplate potentials (m.e.p.ps) is, if anything, increased.2. The release of transmitter by an action potential is reduced in solutions containing Mn, but is still well described by the Poisson equation.3. Log-log plots of e.p.p. quantal content (m) against [Ca] have a mean gradient of 3.73, and a model based on the co-operative action of four calcium ions in excitation-secretion coupling, and competitive inhibition by Mn, was constructed. The model, with its exponent of 4, is shown in fact to predict gradients of less than four for log-log plots of m against [Ca].4. The assumption of competitive inhibition by Mn was supported by modified Lineweaver-Burk plots of m(-(1/4)) against 1/[Ca]. The mean dissociation constants for Ca and Mn were 1.3 mM and 0.15 mM respectively. From the model, an upper estimate of the density of calcium ;receptor sites' of 30 per square micron of nerve terminal was obtained.5. In contrast to its inhibitory effect on evoked release, Mn increases the spontaneous release of transmitter. It is suggested that Mn may increase m.e.p.p. frequency by releasing Ca from an intracellular store.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198587"} {"pmid": "4198588", "title": "Glial fibrillary acidic protein from normal human brain. Purification and properties.", "content": "Glial fibrillary acidic protein from normal human brain. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198588"} {"pmid": "4198589", "title": "Influence of sleep-waking and nociceptor-induced behavior on the activity of supraoptic neurons in the hypothalamus of the monkey.", "content": "Influence of sleep-waking and nociceptor-induced behavior on the activity of supraoptic neurons in the hypothalamus of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198589"} {"pmid": "4198586", "title": "Two cases of Hunter's syndrome--the anaesthetic and operative difficulties in oral surgery.", "content": "Two cases of Hunter's syndrome--the anaesthetic and operative difficulties in oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198586"} {"pmid": "4198590", "title": "Osmosensitivity of hypothalamic magnocellular neuroendocrine cells to intracarotid hypertonic D-glucose in the waking monkey.", "content": "Osmosensitivity of hypothalamic magnocellular neuroendocrine cells to intracarotid hypertonic D-glucose in the waking monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198590"} {"pmid": "4198591", "title": "On perivascular astrocytic membrane specializations in monkey optic nerve.", "content": "On perivascular astrocytic membrane specializations in monkey optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198591"} {"pmid": "4198592", "title": "Supraependymal cells: light and transmission electron microscopy extends scanning electron microscopic demonstration.", "content": "Supraependymal cells: light and transmission electron microscopy extends scanning electron microscopic demonstration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198592"} {"pmid": "4198593", "title": "A clinical and microbiological study of venous catheterization.", "content": "A clinical and microbiological study of venous catheterization. In a prospective study of 210 intravenous catheters and needles 31 (15%) swabs yielded 34 microbial isolates. Twenty-eight were \"non-pathogenic\" skin commensals and six were \"pathogenic\" organisms. Commensals were isolated predominantly from catheters left in situ for only a short time (up to two days) and pathogenic organisms most frequently from specimens left in situ for a longer time. Correlation was not confirmed between colonization and infection, antibiotic therapy or phlebitis. All samples of IV fluids were sterile on culture. Changing the IV catheter at least every two days is recommended.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198593"} {"pmid": "4198594", "title": "Pediatric antimicrobial therapy. II.", "content": "Pediatric antimicrobial therapy. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198594"} {"pmid": "4198595", "title": "Listeria monocytogenes infections in Canada.", "content": "Listeria monocytogenes infections in Canada. Between 1951 and January 1972 listeriosis was diagnosed bacteriologically in 101 Canadian patients. This study adds 80 cases to the 21 reported from Metropolitan Toronto by Sepp and Roy in 1963. The Laboratory Centre for Disease Control, Ottawa, collated epidemiological and clinical data. Serotypes of Listeria monocytogenes included 4b (53), 1 (15), 1b (6), 1a (2), 2 and 3. Clinically, 54 patients had meningitis and 23 septicemia. The mortality rate was 30%.Between 1954 and January 1972 listeriosis affected 15 British Columbian patients: nine were male and six female; 12 were less than 1 or more than 45 years old. Among the patients were a pregnant mother and the son to whom she gave premature birth. A day-old infant and an elderly man died.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198595"} {"pmid": "4198597", "title": "Molecular interactions in the phenomenology of the onset of mental illness.", "content": "Molecular interactions in the phenomenology of the onset of mental illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198597"} {"pmid": "4198599", "title": "Radiosensitivity of oocytes of Drosophila. 3. Sensitivity of class-B oocytes of XX-O and X-X females.", "content": "Radiosensitivity of oocytes of Drosophila. 3. Sensitivity of class-B oocytes of XX-O and X-X females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198599"} {"pmid": "4198603", "title": "Effect of mycorrhizal infection on nitrogen and phosphorus nutrition of ericaceous plants.", "content": "Effect of mycorrhizal infection on nitrogen and phosphorus nutrition of ericaceous plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198603"} {"pmid": "4198601", "title": "Incidence of signs and symptoms in thyroid disease.", "content": "Incidence of signs and symptoms in thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198601"} {"pmid": "4198604", "title": "Tetracycline interference with the bactericidal effect of serum.", "content": "Tetracycline interference with the bactericidal effect of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198604"} {"pmid": "4198605", "title": "Effect of centrifugation on cell adhesion.", "content": "Effect of centrifugation on cell adhesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198605"} {"pmid": "4198607", "title": "Serum transferrin levels and the assessment of protein nutritional status.", "content": "Serum transferrin levels and the assessment of protein nutritional status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198607"} {"pmid": "4198606", "title": "Effects of tiger snake venom on the ultrastructure of motor nerve terminals.", "content": "Effects of tiger snake venom on the ultrastructure of motor nerve terminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198606"} {"pmid": "4198612", "title": "A method for obtaining biochemical and biophysical measurements from rhesus monkey fetuses for prolonged periods.", "content": "A method for obtaining biochemical and biophysical measurements from rhesus monkey fetuses for prolonged periods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198612"} {"pmid": "4198613", "title": "Relationship between 3H-ryanodine uptake and myocardial contractility.", "content": "Relationship between 3H-ryanodine uptake and myocardial contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198613"} {"pmid": "4198614", "title": "Avian thrombocyte aggregation and shape change in vitro.", "content": "Avian thrombocyte aggregation and shape change in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198614"} {"pmid": "4198615", "title": "Immune hemolytic transfusion reactions in monkeys: activation of the kallikrein system.", "content": "Immune hemolytic transfusion reactions in monkeys: activation of the kallikrein system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198615"} {"pmid": "4198616", "title": "Specific antilymphocyte antibody for use in renal transplantation.", "content": "Specific antilymphocyte antibody for use in renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198616"} {"pmid": "4198617", "title": "A constant bile duct anomaly encountered during biliary operation.", "content": "A constant bile duct anomaly encountered during biliary operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198617"} {"pmid": "4198609", "title": "Long term treatment of diabetes mellitus with glibornuride. A new hypoglycemic agent.", "content": "Long term treatment of diabetes mellitus with glibornuride. A new hypoglycemic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198609"} {"pmid": "4198618", "title": "Malaria studies in vitro. II. The measurement of drug activities using leucocyte-free blood-dilution cultures of Plasmodium berghei and 3H-leucine.", "content": "Malaria studies in vitro. II. The measurement of drug activities using leucocyte-free blood-dilution cultures of Plasmodium berghei and 3H-leucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198618"} {"pmid": "4198619", "title": "The isolation from human parotid saliva and partial characterization of the protein core of a major parotid glycoprotein.", "content": "The isolation from human parotid saliva and partial characterization of the protein core of a major parotid glycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198619"} {"pmid": "4198620", "title": "Autonomic innervation of the salivary glands in the marmoset (Callithrix penicillata Jordani); with some gross anatomical and histological observations.", "content": "Autonomic innervation of the salivary glands in the marmoset (Callithrix penicillata Jordani); with some gross anatomical and histological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198620"} {"pmid": "4198621", "title": "Studies on the interaction between rabbit liver pyruvate kinase and its allosteric effector fructose 1,6-diphosphate.", "content": "Studies on the interaction between rabbit liver pyruvate kinase and its allosteric effector fructose 1,6-diphosphate. Preparation of the L form of rabbit liver pyruvate kinase (EC 2.7.1.40) in the presence of fructose 1,6-diphosphate yielded an enzyme which was kinetically identical with the M or muscle-type form of pyruvate kinase found in liver. Chromatographic and dialysis studies of this complex showed that most of the fructose 1,6-diphosphate molecules were loosely bound to the enzyme, but dilution-dissociation studies and binding experiments established that there was a high initial affinity between the enzyme and fructose 1,6-diphosphate (K(assoc.)=2.3x10(9)), and that binding of the loosely bound fructose 1,6-diphosphate was concentration-dependent and a necessary condition to overcome the co-operative interaction observed with the homotropic effector phosphoenolpyruvate. Preparation of the liver enzyme in the absence of EDTA did not yield a predominantly M form of the enzyme, and incubation of the M form in the presence of EDTA did not convert it into the L form, but resulted in inhibition of enzyme activity. Immunological studies confirmed that the L and M forms in liver were distinct, and that preparation of the L form in the presence of fructose 1,6-diphosphate did not produce an enzyme antigenically different from the L form prepared in the absence of this heterotropic effector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198621"} {"pmid": "4198622", "title": "Investigations of the structural function of the J chain in human immunoglobulin M.", "content": "Investigations of the structural function of the J chain in human immunoglobulin M. Human IgM molecules were treated with Na(2)SO(3) or mercaptoethylamine in concentrations ranging from 2 to 14mm or 2 to 22mm respectively. The dissociation of IgM to IgM(s) varied from 0% to 100%. At the intermediate concentrations of either reagent the amount of freed J chains was less than expected. In an attempt to find an explanation for this, IgM was partially dissociated to IgM(s) with mercaptoethylamine. The IgM(s) isolated by gel filtration was divided according to the ascending and descending portions of the elution curve. These portions were treated with 24mm-mercaptoethylamine and analysed for the presence of J chains. Only the ascending portion contained free J chains. Thus, after mild reduction where not all the IgM molecules are dissociated to IgM(s), some J chains remain covalently attached to some IgM(s) molecules although most of the J chains are freed. It was concluded that the J chain could serve as a ;hitch' for IgM(s) molecules forming intact IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198622"} {"pmid": "4198623", "title": "Inhibition by alpha-macroglobulin and other serum proteins.", "content": "Inhibition by alpha-macroglobulin and other serum proteins. 1. Normal human serum was found to inhibit human cathepsin B1. 2. The major inhibitor present in serum was purified and identified as alpha(2)-macroglobulin. 3. alpha(2)-Macroglobulin was found to bind cathepsin B1 in an approximately 1:1 molar ratio. When bound, the enzyme retained about 50% of its proteolytic activity, and up to 80% of its activity against alpha-N-benzoyl-dl-arginine 2-naphthylamide. 4. Pretreatment of alpha(2)-macroglobulin with cathepsin B1 inactivated by exposure to pH8.5 or iodoacetic acid, in large molar excess, did not prevent the subsequent binding of active enzyme. Active enzyme, once bound, was not protected from inhibition by 1-chloro-4-phenyl-3-tosylamido-l-butan-2-one. 5. Cathepsin B1 was also inhibited by human immunoglobulin G, at high concentration. 6. Because it had been suggested that haptoglobin is responsible for the inhibition of ;cathepsin B' by serum, a method was devised for the selective removal of haptoglobin from mixtures of serum proteins by adsorption on haemoglobin covalently linked to Sepharose. No evidence was obtained that haptoglobin has any inhibitory activity against the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198623"} {"pmid": "4198624", "title": "Purification and characterization of two fructose diphosphate aldolases from Escherichia coli (Crookes' strain).", "content": "Purification and characterization of two fructose diphosphate aldolases from Escherichia coli (Crookes' strain). Two fructose diphosphate aldolases (EC 4.1.2.13) were detected in extracts of Escherichia coli (Crookes' strain) grown on pyruvate or lactate. The two enzymes can be resolved by chromatography on DEAE-cellulose at pH7.5, or by gel filtration on Sephadex G-200, and both have been obtained in a pure state. One is a typical bacterial aldolase (class II) in that it is strongly inhibited by metal-chelating agents and is reactivated by bivalent metal ions, e.g. Ca(2+), Zn(2+). It is a dimer with a molecular weight of approx. 70000, and the K(m) value for fructose diphosphate is about 0.85mm. The other aldolase is not dependent on metal ions for its activity, but is inhibited by reduction with NaBH(4) in the presence of substrate. The K(m) value for fructose diphosphate is about 20mum (although the Lineweaver-Burk plot is not linear) and the enzyme is probably a tetramer with molecular weight approx. 140000. It has been crystallized. On the basis of these properties it is tentatively assigned to class I. The appearance of a class I aldolase in bacteria was unexpected, and its synthesis in E. coli is apparently favoured by conditions of gluconeogenesis. Only aldolase of class II was found in E. coli that had been grown on glucose. The significance of these results for the evolution of fructose diphosphate aldolases is briefly discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198624"} {"pmid": "4198625", "title": "Species variations in the O-methylation of n-butyl 4-hydroxy-3,5-diiodobenzoate.", "content": "Species variations in the O-methylation of n-butyl 4-hydroxy-3,5-diiodobenzoate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198625"} {"pmid": "4198633", "title": "Radiographic studies of amyloidosis.", "content": "Radiographic studies of amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198633"} {"pmid": "4198634", "title": "Plasmodium spp.: dispersion of malarial oocyst populations in anopheline and culicine mosquitoes.", "content": "Plasmodium spp.: dispersion of malarial oocyst populations in anopheline and culicine mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198634"} {"pmid": "4198635", "title": "Humoral antibody response and Ig characterization of the specific agglutinins in rabbits during experimental American trypanosomiasis.", "content": "Humoral antibody response and Ig characterization of the specific agglutinins in rabbits during experimental American trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198635"} {"pmid": "4198636", "title": "Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants.", "content": "Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198636"} {"pmid": "4198639", "title": "Binding of thyroid hormones to a soluble fraction from porcine anterior pituitary.", "content": "Binding of thyroid hormones to a soluble fraction from porcine anterior pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198639"} {"pmid": "4198641", "title": "Ultrastructural development of Nostoc muscorum A.", "content": "Ultrastructural development of Nostoc muscorum A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198641"} {"pmid": "4198640", "title": "Growth of pseudomonas species on phenylacetamide.", "content": "Growth of pseudomonas species on phenylacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198640"} {"pmid": "4198642", "title": "Unbalanced growth and replication of chloroplast populations in Euglena gracilis.", "content": "Unbalanced growth and replication of chloroplast populations in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198642"} {"pmid": "4198644", "title": "Inactivation of southern bean mosaic virus and its ribonucleic acid by nitrous acid and ultraviolet light.", "content": "Inactivation of southern bean mosaic virus and its ribonucleic acid by nitrous acid and ultraviolet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198644"} {"pmid": "4198645", "title": "Superficial venous arrangement of the face and neck of the tufted capuchin, Cebus apella Linnaeus, 1758.", "content": "Superficial venous arrangement of the face and neck of the tufted capuchin, Cebus apella Linnaeus, 1758.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198645"} {"pmid": "4198643", "title": "The isolation of tyrosinase from Aspergillus nidulans, its kinetic and molecular properties and some consideration of its activity in vivo.", "content": "The isolation of tyrosinase from Aspergillus nidulans, its kinetic and molecular properties and some consideration of its activity in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198643"} {"pmid": "4198646", "title": "Studies on human malaria in Aotus monkeys. I. Sporozoite transmission of Plasmodium vivax from El Salvador.", "content": "Studies on human malaria in Aotus monkeys. I. Sporozoite transmission of Plasmodium vivax from El Salvador.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198646"} {"pmid": "4198647", "title": "Studies on human malaria in Aotus monkeys. II. Establishment of a strain of Plasmodium falciparum from Panama.", "content": "Studies on human malaria in Aotus monkeys. II. Establishment of a strain of Plasmodium falciparum from Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198647"} {"pmid": "4198648", "title": "The 2-mercaptoethanol labile immunoglobulin response of beagles experimentally infected with Dirofilaria immitis.", "content": "The 2-mercaptoethanol labile immunoglobulin response of beagles experimentally infected with Dirofilaria immitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198648"} {"pmid": "4198649", "title": "Demodectic mites of subhuman primates I: Demodex saimiri sp. n. (Acari: Demodicidae) from the squirrel monkey, Saimiri sciureus.", "content": "Demodectic mites of subhuman primates I: Demodex saimiri sp. n. (Acari: Demodicidae) from the squirrel monkey, Saimiri sciureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198649"} {"pmid": "4198650", "title": "A simple method for the detection of human congenital Chagas' disease.", "content": "A simple method for the detection of human congenital Chagas' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198650"} {"pmid": "4198651", "title": "Ultrastructural changes in Babesia argentina-infected erythrocytes in kidney capillaries.", "content": "Ultrastructural changes in Babesia argentina-infected erythrocytes in kidney capillaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198651"} {"pmid": "4198652", "title": "Haemogregarina platessae Lebailly (=H. achiri Saunders) from the Hogchoker in Maryland.", "content": "Haemogregarina platessae Lebailly (=H. achiri Saunders) from the Hogchoker in Maryland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198652"} {"pmid": "4198656", "title": "The sources of hospital infection.", "content": "The sources of hospital infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198656"} {"pmid": "4198657", "title": "Immunity to brucella infection.", "content": "Immunity to brucella infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198657"} {"pmid": "4198658", "title": "East Coast fever: correlation between the morphology and infectivity of Theileria parva developing in its tick vector.", "content": "East Coast fever: correlation between the morphology and infectivity of Theileria parva developing in its tick vector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198658"} {"pmid": "4198659", "title": "Sound spectral properties of conditioned vocalization in monkeys.", "content": "Sound spectral properties of conditioned vocalization in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198659"} {"pmid": "4198660", "title": "Biological versatility and earth history.", "content": "Biological versatility and earth history. Examples from various plant and animal groups indicate that there has been a general increase in potential versatility of form, determined by the number and range of independently varying morphogenetic parameters, among taxa appearing at successively younger stages in the fossil record. Taxa or body plans with higher potential versatility have tended to replace less potentially versatile groups in the same or similar adaptive zone through time. Greater potential diversity allows for greater homeostasis, efficiency, and integration of structures and functions, and for an increase in size of the potential adaptive zone. In contrast, chemical versatility has generally decreased within groups from the pre-Cambrian to the Phanerozoic, partly as the result of apparent changes in the chemical environment and partly as the consequence of selection for efficiency and greater metabolic ease of handling of certain materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198660"} {"pmid": "4198662", "title": "Carbon dioxide hydration activity of carbonic anhydrase: paradoxical consequences of the unusually rapid catalysis.", "content": "Carbon dioxide hydration activity of carbonic anhydrase: paradoxical consequences of the unusually rapid catalysis. The kinetic parameters for carbon dioxide hydration catalysis by carbonic anhydrase (EC 4.2.1.1) present an apparent paradox. The assumption of H(2)CO(3) as the hydration product requires the rate of recombination of H(2)CO(3) with enzyme to be faster than the diffusion limit. The alternative assumption of HCO(3) (-) as the product of hydration likewise requires active-site ionization rates to exceed the diffusion limit. We previously postulated the presence of special means for rapid active-site ionization. It is shown here that when proton transfer between enzyme and buffer species is taken into account, there is no need to invoke rates exceeding the diffusion limit. Bicarbonate ion thus appears as the most probable hydration product and dehydration substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198662"} {"pmid": "4198661", "title": "Crossing-over between X AND Y chromosomes during ribosomal DNA magnification in Drosophila melanogaster.", "content": "Crossing-over between X AND Y chromosomes during ribosomal DNA magnification in Drosophila melanogaster. In genetic combinations undergoing ribosomal DNA magnification, the frequency of crossing-over between X and Y chromosomes is increased at least 20-fold above that in similar combinations not undergoing magnification. Such recombination occurs at the ribosomal DNA level. The data are consistent with a model where extra copies of ribosomal DNA are formed which, after circularization, are integrated into the chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198661"} {"pmid": "4198664", "title": "The mental hospital as an institution.", "content": "The mental hospital as an institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198664"} {"pmid": "4198663", "title": "Segregation during ascidian embryogenesis of egg cytoplasmic information for tissue-specific enzyme development.", "content": "Segregation during ascidian embryogenesis of egg cytoplasmic information for tissue-specific enzyme development. Cleavage-arrested embryos of the ascidian Ciona intestinalis were able to differentiate two tissue-specific enzymes-muscle acetylcholinesterase (EC 3.1.1.7) and brain pigment cell tyrosinase (EC 1.10.3.1). Cytochalasin B, colchicine, Colcemid, and podophyllotoxin were used as cleavage inhibitors at early embryonic stages up to the 64-cell stage. Only certain cells in the cleavage-arrested embryos developed these histochemically detectable enzymes, and this ability followed the cell lineage patterns for the two tissues. This result implies the presence of specific positional information in the egg cytoplasm that is differentially segregated during cleavage. There were distinct and separate puromycin and actinomycin D sensitivity periods for the occurrence of each enzyme during development of both normal and cleavage-arrested embryos. The segregated information is apparently neither the enzyme proteins nor RNA templates for enzyme synthesis, but is probably concerned with activation of appropriate genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198663"} {"pmid": "4198666", "title": "The influence of fluid shear on the kinetics of blood coagulation reactions.", "content": "The influence of fluid shear on the kinetics of blood coagulation reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198666"} {"pmid": "4198665", "title": "The impact of waterborne diseases on mortality.", "content": "The impact of waterborne diseases on mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198665"} {"pmid": "4198668", "title": "Bio-artificial liver: a combined system of hemodialysis and baboon liver perfusion.", "content": "Bio-artificial liver: a combined system of hemodialysis and baboon liver perfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198668"} {"pmid": "4198667", "title": "Validation and bioengineering aspects of an implantable glucose sensor.", "content": "Validation and bioengineering aspects of an implantable glucose sensor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198667"} {"pmid": "4198655", "title": "Economic class and use of physician services.", "content": "Economic class and use of physician services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198655"} {"pmid": "4198669", "title": "Morphologic studies of dialysis membranes adherence of blood components to air rinsed coils.", "content": "Morphologic studies of dialysis membranes adherence of blood components to air rinsed coils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198669"} {"pmid": "4198670", "title": "Membrane lung oxygenation for temporary support of the failing transplanted lung.", "content": "Membrane lung oxygenation for temporary support of the failing transplanted lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198670"} {"pmid": "4198672", "title": "An outbreak of anthrax at the Chester Zoological Gardens.", "content": "An outbreak of anthrax at the Chester Zoological Gardens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198672"} {"pmid": "4198671", "title": "The surface bonded, covalently crosslinked urokinase synthetic surface. In vitro and chronic in vivo studies.", "content": "The surface bonded, covalently crosslinked urokinase synthetic surface. In vitro and chronic in vivo studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198671"} {"pmid": "4198673", "title": "Immunological relationship between border disease, mucosal disease and swine fever.", "content": "Immunological relationship between border disease, mucosal disease and swine fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198673"} {"pmid": "4198674", "title": "Human and macaque blue cones studied with electroretinography.", "content": "Human and macaque blue cones studied with electroretinography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198674"} {"pmid": "4198678", "title": "Persistent mixed field polyagglutinability. An immunofluorescence study in genetically abnormal red cells.", "content": "Persistent mixed field polyagglutinability. An immunofluorescence study in genetically abnormal red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198678"} {"pmid": "4198679", "title": "Secondary stimulation of Rh antibodies by kidney allografts from Rh-positive donors.", "content": "Secondary stimulation of Rh antibodies by kidney allografts from Rh-positive donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198679"} {"pmid": "4198680", "title": "A new blood group antigen, Hov.", "content": "A new blood group antigen, Hov.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198680"} {"pmid": "4198681", "title": "Rhesus blood group notations.", "content": "Rhesus blood group notations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198681"} {"pmid": "4198682", "title": "A service-integrated approach to clinical pharmacy practice through a hyperalimentation program.", "content": "A service-integrated approach to clinical pharmacy practice through a hyperalimentation program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198682"} {"pmid": "4198683", "title": "Pseudomonas pneumonia. A retrospective study of 36 cases.", "content": "Pseudomonas pneumonia. A retrospective study of 36 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198683"} {"pmid": "4198684", "title": "Antimicrobial activity of tobramycin and gentamicin used in combination with cephalothin and carbenicillin.", "content": "Antimicrobial activity of tobramycin and gentamicin used in combination with cephalothin and carbenicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198684"} {"pmid": "4198686", "title": "Carbon monoxide inhalation effects following myocardial infarction in monkeys.", "content": "Carbon monoxide inhalation effects following myocardial infarction in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198686"} {"pmid": "4198687", "title": "Antitrypsin deficiency and abnormal protease inhibitor phenotypes.", "content": "Antitrypsin deficiency and abnormal protease inhibitor phenotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198687"} {"pmid": "4198689", "title": "Comparison of antigenicity of rat collagen prepared by various methods.", "content": "Comparison of antigenicity of rat collagen prepared by various methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198689"} {"pmid": "4198688", "title": "Measles giant cell pneumonia in an adult following long-term chemotherapy.", "content": "Measles giant cell pneumonia in an adult following long-term chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198688"} {"pmid": "4198685", "title": "Pollutant burdens and biological response.", "content": "Pollutant burdens and biological response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198685"} {"pmid": "4198690", "title": "Studies on the epizootiology of bovine babesiosis in north eastern New South Wales.", "content": "Studies on the epizootiology of bovine babesiosis in north eastern New South Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198690"} {"pmid": "4198691", "title": "Studies on the epizootiology of bovine babesiosis in common border areas of New South Wales and Queensland.", "content": "Studies on the epizootiology of bovine babesiosis in common border areas of New South Wales and Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198691"} {"pmid": "4198692", "title": "Inhibition of prostaglandin biosynthesis by 7-oxa- and 5-oxa-prostaglandin analogues.", "content": "Inhibition of prostaglandin biosynthesis by 7-oxa- and 5-oxa-prostaglandin analogues. Some oxaprostaglandin derivatives have been shown to inhibit prostaglandin biosynthesis from arachidonate by a particulate prostaglandin synthetase preparation. The most potent inhibitor was 5-oxaprost-13-trans-enoate, and inhibition by this compound appeared to be competitive. Certain structure-activity relationships were ascertained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198692"} {"pmid": "4198698", "title": "Lung function after mantle field irradiation in Hodgkin's disease.", "content": "Lung function after mantle field irradiation in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198698"} {"pmid": "4198699", "title": "Role of radiotherapy in the treatment of cancer of the tongue. A retrospective analysis on TNM-staged tumors treated between 1958 and 1968.", "content": "Role of radiotherapy in the treatment of cancer of the tongue. A retrospective analysis on TNM-staged tumors treated between 1958 and 1968.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198699"} {"pmid": "4198700", "title": "Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant \"Triton\" tumors).", "content": "Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant \"Triton\" tumors).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198700"} {"pmid": "4198701", "title": "Regional blood flows in unanaesthetized rhesus monkeys during myocardial infarction.", "content": "Regional blood flows in unanaesthetized rhesus monkeys during myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198701"} {"pmid": "4198702", "title": "Ankle arthrography in acute sprains.", "content": "Ankle arthrography in acute sprains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198702"} {"pmid": "4198703", "title": "Effects of immune environments upon bone in vitro. I. Cytotoxicity of antibodies to bone homogenates.", "content": "Effects of immune environments upon bone in vitro. I. Cytotoxicity of antibodies to bone homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198703"} {"pmid": "4198704", "title": "Experimental scoliosis.", "content": "Experimental scoliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198704"} {"pmid": "4198706", "title": "A novel monoquaternary neuromuscular blocking agent.", "content": "A novel monoquaternary neuromuscular blocking agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198706"} {"pmid": "4198707", "title": "Constant oxygen enhancement ratio during the mitotic cell cycle in x-rayed Drosophila melanogaster embryos.", "content": "Constant oxygen enhancement ratio during the mitotic cell cycle in x-rayed Drosophila melanogaster embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198707"} {"pmid": "4198711", "title": "The use of antibiotics in hospital.", "content": "The use of antibiotics in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198711"} {"pmid": "4198710", "title": "Studies on rabbit secretory and serum antibodies to hog intrinsic factor.", "content": "Studies on rabbit secretory and serum antibodies to hog intrinsic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198710"} {"pmid": "4198712", "title": "Correlation between PaCO2 and regional cerebral blood volume by x-ray fluorescence.", "content": "Correlation between PaCO2 and regional cerebral blood volume by x-ray fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198712"} {"pmid": "4198714", "title": "The use of polyacrylamide gel electrophoresis in taxonomy of Brucella.", "content": "The use of polyacrylamide gel electrophoresis in taxonomy of Brucella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198714"} {"pmid": "4198713", "title": "The properties of virginiamycin-resistant mutants of Bacillus subtilis.", "content": "The properties of virginiamycin-resistant mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198713"} {"pmid": "4198716", "title": "Subunit structure of cholera toxin.", "content": "Subunit structure of cholera toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198716"} {"pmid": "4198715", "title": "Penicillin production by lysine auxotrophs of Penicillium chrysogenum.", "content": "Penicillin production by lysine auxotrophs of Penicillium chrysogenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198715"} {"pmid": "4198717", "title": "A bacitracin-negative mutant of Bacillus licheniformis which is able to sporulate.", "content": "A bacitracin-negative mutant of Bacillus licheniformis which is able to sporulate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198717"} {"pmid": "4198718", "title": "Mutants of Pseudomonas aeruginosa with impaired -lactamase inducibility and increased sensitivity to -lactam antibiotics.", "content": "Mutants of Pseudomonas aeruginosa with impaired -lactamase inducibility and increased sensitivity to -lactam antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198718"} {"pmid": "4198719", "title": "Cloxacillin and nafcillin: serum binding and its relationship to antibacterial effect in mice.", "content": "Cloxacillin and nafcillin: serum binding and its relationship to antibacterial effect in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198719"} {"pmid": "4198720", "title": "Nutritional profiles of Neisseria gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing.", "content": "Nutritional profiles of Neisseria gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198720"} {"pmid": "4198721", "title": "The silvered leaf-monkey of Malaysia, Presbytis cristatus: disease model for human scrub typhus.", "content": "The silvered leaf-monkey of Malaysia, Presbytis cristatus: disease model for human scrub typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198721"} {"pmid": "4198722", "title": "Experimental gingivitis in Macaca speciosa monkeys: clinical, bacteriologic and histologic similarities to human gingivitis.", "content": "Experimental gingivitis in Macaca speciosa monkeys: clinical, bacteriologic and histologic similarities to human gingivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198722"} {"pmid": "4198723", "title": "Posttraumatic transient cerebral blindness. Association with migraine and seizure diatheses.", "content": "Posttraumatic transient cerebral blindness. Association with migraine and seizure diatheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198723"} {"pmid": "4198724", "title": "Serological typing of Pseudomonas aerginosa from mouse breeding colonies.", "content": "Serological typing of Pseudomonas aerginosa from mouse breeding colonies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198724"} {"pmid": "4198726", "title": "Changes in serotype of Pseudomonas aeruginosa.", "content": "Changes in serotype of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198726"} {"pmid": "4198725", "title": "Passive hemagglutination reaction using formalinized sheep erythrocytes treated with tannin and coated with protein moiety of the endotoxin (OEP) of Pseudomonas aeruginosa.", "content": "Passive hemagglutination reaction using formalinized sheep erythrocytes treated with tannin and coated with protein moiety of the endotoxin (OEP) of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198725"} {"pmid": "4198727", "title": "Micellar structure and endotoxic activities of gram-negative lipopolysaccharides.", "content": "Micellar structure and endotoxic activities of gram-negative lipopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198727"} {"pmid": "4198728", "title": "Characterization of anti-cord factor antibody.", "content": "Characterization of anti-cord factor antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198728"} {"pmid": "4198729", "title": "Regulation of staphylococcal enterotoxin B synthesis and its relation to other extracellular proteins.", "content": "Regulation of staphylococcal enterotoxin B synthesis and its relation to other extracellular proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198729"} {"pmid": "4198730", "title": "Some properties of the diphtheria toxin fragment produced by a beta phage-mutant lysogen of Corynebacterium diphtheriae.", "content": "Some properties of the diphtheria toxin fragment produced by a beta phage-mutant lysogen of Corynebacterium diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198730"} {"pmid": "4198731", "title": "Methylation of basic residues in structural proteins.", "content": "Methylation of basic residues in structural proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198731"} {"pmid": "4198734", "title": "Serial reversal learning by monkeys with inferotemporal or foveal prestriate lesions.", "content": "Serial reversal learning by monkeys with inferotemporal or foveal prestriate lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198734"} {"pmid": "4198735", "title": "Diurnal variation of ileum motility in monkey during different feeding and avoidance-conditioning schedules.", "content": "Diurnal variation of ileum motility in monkey during different feeding and avoidance-conditioning schedules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198735"} {"pmid": "4198736", "title": "Hypothalamic \"coding\" in the unanesthetized monkey of noradrenergic sites mediating feeding and thermoregulation.", "content": "Hypothalamic \"coding\" in the unanesthetized monkey of noradrenergic sites mediating feeding and thermoregulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198736"} {"pmid": "4198738", "title": "Brain mechanisms in movement.", "content": "Brain mechanisms in movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198738"} {"pmid": "4198737", "title": "Premotor cortex and instrumental behavior in monkeys.", "content": "Premotor cortex and instrumental behavior in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198737"} {"pmid": "4198739", "title": "Effect of the bee venom and melittin on plasma cortisol in the unanesthetized monkey.", "content": "Effect of the bee venom and melittin on plasma cortisol in the unanesthetized monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198739"} {"pmid": "4198742", "title": "Absorption from mucosal surfaces.", "content": "Absorption from mucosal surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198742"} {"pmid": "4198743", "title": "The stimulation of eccrine sweating by pharmacologic agents.", "content": "The stimulation of eccrine sweating by pharmacologic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198743"} {"pmid": "4198745", "title": "When to use two or more antibiotics.", "content": "When to use two or more antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198745"} {"pmid": "4198746", "title": "Penicillin phenoxymethyl. Use in rheumatic fever prophylaxis.", "content": "Penicillin phenoxymethyl. Use in rheumatic fever prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198746"} {"pmid": "4198747", "title": "Stickler syndrome in a pedigree of Pierre Robin syndrome.", "content": "Stickler syndrome in a pedigree of Pierre Robin syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198747"} {"pmid": "4198740", "title": "Estrogenic effect in vaginal smears in cases of carcinoma in situ and microinvasive carcinoma of the uterine cervix.", "content": "Estrogenic effect in vaginal smears in cases of carcinoma in situ and microinvasive carcinoma of the uterine cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198740"} {"pmid": "4198748", "title": "Non-atheromatous stenosis and occlusion of the internal carotid artery and its main branches.", "content": "Non-atheromatous stenosis and occlusion of the internal carotid artery and its main branches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198748"} {"pmid": "4198749", "title": "Angiographic evidence for cerebral (opercular) swelling in patients with seizures.", "content": "Angiographic evidence for cerebral (opercular) swelling in patients with seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198749"} {"pmid": "4198750", "title": "Tuberculoma of the brain (revisited).", "content": "Tuberculoma of the brain (revisited).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198750"} {"pmid": "4198756", "title": "Comparison of precipitation malarial antibodies produced by indigenous immune Gambians and an infected European.", "content": "Comparison of precipitation malarial antibodies produced by indigenous immune Gambians and an infected European.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198756"} {"pmid": "4198758", "title": "Beta-ketothiolase from Hydrogenomonas eutropha H16 and its significance in the regulation of poly-beta-hydroxybutyrate metabolism.", "content": "Beta-ketothiolase from Hydrogenomonas eutropha H16 and its significance in the regulation of poly-beta-hydroxybutyrate metabolism. 1. beta-Ketothiolase was purified 49-fold from fructose-grown cells of Hydrogenomonas eutropha H16 with a yield of 27%; the purification procedure involved precipitation by cetyltrimethylammonium bromide, DEAE-cellulose chromatography and exclusion chromatography on Sephadex G-200; the freeze-dried enzyme is stable. The molecular weight determined by sucrose-gradient centrifugation (8.2S) and by gel filtration is 147000-150000. The optimum pH for the cleavage reaction is 8.1, that for the condensation reaction 7.8, both measured in Tris-HCl buffer. 2. The kinetics of the cleavage reaction are described. Substrate-saturation curves were measured with both acetoacetyl-CoA and CoA as the variable substrates. The concentration of the second substrate was kept constant and was varied during successive experiments. The cleavage reaction is characterized by substrate inhibition by acetoacetyl-CoA, which is partially relieved by free CoA. Hill plots indicate two acetoacetyl-CoA-binding sites. 3. The substrate(acetyl-CoA)-saturation curve for the condensation reaction is hyperbolic. The K(m) was 3.9x10(-4)m-acetyl-CoA. In the presence of CoA sigmoidal curves were obtained, with an increasing sigmoidicity from 0.03 to 0.30mm-CoA. The inhibitory action of CoA on the beta-ketothiolase condensation reaction and its possible involvement in the regulation of poly-beta-hydroxybutyrate synthesis and degradation are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198758"} {"pmid": "4198759", "title": "Lethal effect of rifampicin in Bacillus subtilis as a complicating factor in the assessment of the lifetime of messenger ribonucleic acid.", "content": "Lethal effect of rifampicin in Bacillus subtilis as a complicating factor in the assessment of the lifetime of messenger ribonucleic acid. The bactericidal action of rifampicin was compared with that of chloramphenicol in growing and in sporulating cultures of Bacillus subtilis 168. Chloramphenicol kills cells only very slowly, but exposure to rifampicin kills over 95% of cells in a few minutes, causing gross physical damage, which is visible in both phase-contrast and electron microscopy. This is accompanied by a fall in O(2) consumption and by lysis. Experiments with synchronized cultures showed that susceptibility to the lethal effect of rifampicin is greater when the cells are dividing. The results suggest that the synthesis of some species of RNA other than mRNA may be necessary for the maintenance of cell integrity, although experiments with actinomycin D do not altogether fit this interpretation. However, we conclude that rifampicin is too toxic to use as an antibiotic for assessing the lifetime of mRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198759"} {"pmid": "4198761", "title": "Properties of tRNAPhe from Drosophila.", "content": "Properties of tRNAPhe from Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198761"} {"pmid": "4198760", "title": "Control of the production of exo-beta-N-acetylglucosaminidase by Bacillus subtilis B.", "content": "Control of the production of exo-beta-N-acetylglucosaminidase by Bacillus subtilis B. 1. The control of exo-beta-N-acetylglucosaminidase (EC 3.2.1.30) production by Bacillus subtilis B growing on a chemically defined medium was studied. 2. The enzyme was repressed during exponential growth by those carbon sources that enter the glycolytic pathway above the level of phosphoenolpyruvate. When exponential growth ceased as a result of low concentrations of the nitrogen, carbon or metal ion components of the medium, the enzyme was formed and its amount could be increased by the addition of cell-wall fragments as inducer. 3. The enzyme was de-repressed and could be induced during exponential growth on non-glycolytic compounds metabolized directly into pyruvate, acetyl-CoA or tricarboxylic acid cycle intermediates. 4. The major difference in the metabolism of the organism utilizing these two groups of compound was the existence of high activities of phosphoenolpyruvate carboxylase required for gluconeogenesis. 5. It is concluded that the de-repression of glucosaminidase occurs when the only principal change detected in the intermediary metabolism of the organism was the presence of high activities of phosphoenolpyruvate carboxylase. 6. When the organism was grown on media containing repressing compounds, the enzyme was only de-repressed on entry of the cells into the initial stages of sporulation, where phosphoenolpyruvate carboxylase activity, even in the presence of excess of glucose, increased in parallel with glucosaminidase, neutral proteinase and alkaline phosphatase activities. 7. These results suggest a strong link, at the level of the tricarboxylic acid cycle, between the control of phosphoenolpyruvate carboxylase and the control of the de-repression of glucosaminidase and sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198760"} {"pmid": "4198762", "title": "Association of a ribonuclease with the 50-S ribosomal subunit of Escherichia coli MRE 600.", "content": "Association of a ribonuclease with the 50-S ribosomal subunit of Escherichia coli MRE 600.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198762"} {"pmid": "4198763", "title": "Protein synthesis by rat cardiac muscle myofibrils.", "content": "Protein synthesis by rat cardiac muscle myofibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198763"} {"pmid": "4198764", "title": "Physical characterization of alpha-amylase inhibitors from wheat.", "content": "Physical characterization of alpha-amylase inhibitors from wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198764"} {"pmid": "4198765", "title": "Bovine intestinal calcium-binding proteins. Purification and some properties.", "content": "Bovine intestinal calcium-binding proteins. Purification and some properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198765"} {"pmid": "4198766", "title": "The myoglobin of primates. 4. New World monkeys: Cebidae: (1) Saimiri sciureus (squirrel monkey); (2) Lagothrix lagothricha (Humboldt's woolly monkey). Callitrichidae: Callithrix jacchus (common marmoset).", "content": "The myoglobin of primates. 4. New World monkeys: Cebidae: (1) Saimiri sciureus (squirrel monkey); (2) Lagothrix lagothricha (Humboldt's woolly monkey). Callitrichidae: Callithrix jacchus (common marmoset).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198766"} {"pmid": "4198767", "title": "Snake venom toxins the amino acid sequences of two toxins from Ophiophagus hannah (King cobra) venom.", "content": "Snake venom toxins the amino acid sequences of two toxins from Ophiophagus hannah (King cobra) venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198767"} {"pmid": "4198755", "title": "Evaluation of a free thyroxine index.", "content": "Evaluation of a free thyroxine index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198755"} {"pmid": "4198769", "title": "Changes in glomerular filtration rate during long-term treatment with propranolol in patients with arterial hypertension.", "content": "Changes in glomerular filtration rate during long-term treatment with propranolol in patients with arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198769"} {"pmid": "4198770", "title": "Clinical applications of thyrotrophin-releasing hormone.", "content": "Clinical applications of thyrotrophin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198770"} {"pmid": "4198771", "title": "The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat.", "content": "The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198771"} {"pmid": "4198773", "title": "Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey.", "content": "Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198773"} {"pmid": "4198772", "title": "CI-750, A novel antidiarrheal agent.", "content": "CI-750, A novel antidiarrheal agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198772"} {"pmid": "4198768", "title": "Pharmacokinetic study of a patient with diphenylhydantoin toxicity.", "content": "Pharmacokinetic study of a patient with diphenylhydantoin toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198768"} {"pmid": "4198774", "title": "The effects of verapamil on metabolism and contractility of the toad skeletal muscle.", "content": "The effects of verapamil on metabolism and contractility of the toad skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198774"} {"pmid": "4198752", "title": "Inhibition by L-triiodothyronine and dexamethasone of TSH response to thyrotropin releasing hormone in man.", "content": "Inhibition by L-triiodothyronine and dexamethasone of TSH response to thyrotropin releasing hormone in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198752"} {"pmid": "4198777", "title": "Transgastric jejunal intubation.", "content": "Transgastric jejunal intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198777"} {"pmid": "4198779", "title": "Effect of intravenous polyunsaturated phosphatidyl choline in experimental atherosclerosis.", "content": "Effect of intravenous polyunsaturated phosphatidyl choline in experimental atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198779"} {"pmid": "4198789", "title": "Histochemical distribution of phosphorylase in the central nervous system of primates, Saimiri sciureus and Macaca mulatta.", "content": "Histochemical distribution of phosphorylase in the central nervous system of primates, Saimiri sciureus and Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198789"} {"pmid": "4198790", "title": "Surface ultrastructure of reproductive tract in female crab-eating (M. fascicularis) and bonnet (M. radiata) macaques.", "content": "Surface ultrastructure of reproductive tract in female crab-eating (M. fascicularis) and bonnet (M. radiata) macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198790"} {"pmid": "4198791", "title": "Lateral hypothalamic nuclei in the macaque (Macaca mulatta) brain: myeloarchitectonics.", "content": "Lateral hypothalamic nuclei in the macaque (Macaca mulatta) brain: myeloarchitectonics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198791"} {"pmid": "4198796", "title": "Weight loss following thermal injury.", "content": "Weight loss following thermal injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198796"} {"pmid": "4198800", "title": "Beta-blocking agents in hay fever.", "content": "Beta-blocking agents in hay fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198800"} {"pmid": "4198799", "title": "Penicillins for Haemophilus infections.", "content": "Penicillins for Haemophilus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198799"} {"pmid": "4198814", "title": "Isolation of alpha-fetoprotein-producing cells from Yoshida ascites sarcoma and its clone.", "content": "Isolation of alpha-fetoprotein-producing cells from Yoshida ascites sarcoma and its clone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198814"} {"pmid": "4198815", "title": "Presence of antigen related to the carcinoembryonic antigen in feces of normal adults.", "content": "Presence of antigen related to the carcinoembryonic antigen in feces of normal adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198815"} {"pmid": "4198816", "title": "Tin-117m: production, chemistry and evaluation as a bone-scanning agent.", "content": "Tin-117m: production, chemistry and evaluation as a bone-scanning agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198816"} {"pmid": "4198817", "title": "Structure and biosynthesis of basement membranes.", "content": "Structure and biosynthesis of basement membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198817"} {"pmid": "4198818", "title": "Evolution of asymbiotic nitrogen fixation.", "content": "Evolution of asymbiotic nitrogen fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198818"} {"pmid": "4198820", "title": "The 1974 reorganization of the British National Health Service--aims and issues.", "content": "The 1974 reorganization of the British National Health Service--aims and issues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198820"} {"pmid": "4198821", "title": "Sternoarticular septic arthritis in heroin users.", "content": "Sternoarticular septic arthritis in heroin users.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198821"} {"pmid": "4198822", "title": "Impaired carbohydrate metabolism during a mild viral illness.", "content": "Impaired carbohydrate metabolism during a mild viral illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198822"} {"pmid": "4198825", "title": "Regulation of protein synthesis in rat liver cell-free systems by amino acids.", "content": "Regulation of protein synthesis in rat liver cell-free systems by amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198825"} {"pmid": "4198826", "title": "Photon interaction processes--their relative importance in bone and muscle.", "content": "Photon interaction processes--their relative importance in bone and muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198826"} {"pmid": "4198824", "title": "Inhibition of respiration in the isolated eccrine sweat gland by ethacrynic acid.", "content": "Inhibition of respiration in the isolated eccrine sweat gland by ethacrynic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198824"} {"pmid": "4198828", "title": "Dosimetry for total-body electron-beam therapy in the treatment of mycosis fungoides.", "content": "Dosimetry for total-body electron-beam therapy in the treatment of mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198828"} {"pmid": "4198827", "title": "Cartilaginous esophageal ring: a cause of esophageal stenosis in infants and children.", "content": "Cartilaginous esophageal ring: a cause of esophageal stenosis in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198827"} {"pmid": "4198829", "title": "Achievement of uniform dose without overlap in multi-port treatment fields, including inter-port shaped blocks.", "content": "Achievement of uniform dose without overlap in multi-port treatment fields, including inter-port shaped blocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198829"} {"pmid": "4198831", "title": "Chromomeres and genes.", "content": "Chromomeres and genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198831"} {"pmid": "4198830", "title": "Puffing patterns in Drosophila melanogaster and related species.", "content": "Puffing patterns in Drosophila melanogaster and related species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198830"} {"pmid": "4198832", "title": "Replication in polytene chromosomes.", "content": "Replication in polytene chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198832"} {"pmid": "4198834", "title": "A venereological panorama.", "content": "A venereological panorama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198834"} {"pmid": "4198836", "title": "The Australia antigen in Brazilian blood donors.", "content": "The Australia antigen in Brazilian blood donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198836"} {"pmid": "4198837", "title": "Biosynthesis of vitamin B12 by mesophilic and thermophilic strains of Bacillus megaterium.", "content": "Biosynthesis of vitamin B12 by mesophilic and thermophilic strains of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198837"} {"pmid": "4198838", "title": "Development of tolerance to street heroin in addicted and nonaddicted primates.", "content": "Development of tolerance to street heroin in addicted and nonaddicted primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198838"} {"pmid": "4198839", "title": "Parenteral feeding of surgical patients.", "content": "Parenteral feeding of surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198839"} {"pmid": "4198833", "title": "The hydrogen clearance method in assessment of blood flow in cortex, white matter and deep nuclei of baboons.", "content": "The hydrogen clearance method in assessment of blood flow in cortex, white matter and deep nuclei of baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198833"} {"pmid": "4198850", "title": "Neurofibroma of the larynx occurring with Von Recklinghausen disease. Report of a case.", "content": "Neurofibroma of the larynx occurring with Von Recklinghausen disease. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198850"} {"pmid": "4198851", "title": "The chain length of the glycans in bacterial cell walls.", "content": "The chain length of the glycans in bacterial cell walls. The glycan chain length of peptidoglycan was measured by reduction with NaB(3)H(4) and isolation of the resulting muramitol, indicative of the length of the chains as biosynthesized, and glucosaminol, which measured the length of the chains after rupture by endo-beta-N-acetylglucosaminidases. Measurement of the non-reducing terminal N-acetylglucosamine by Smith degradation confirmed the result.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198851"} {"pmid": "4198866", "title": "Influence of dexamethasone on TRF induced TSH release in rats.", "content": "Influence of dexamethasone on TRF induced TSH release in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198866"} {"pmid": "4198867", "title": "A renewal attempt to compare the affinity of thyroxine-binding-globulin to thyroxine in normal and hyperthyroid sera.", "content": "A renewal attempt to compare the affinity of thyroxine-binding-globulin to thyroxine in normal and hyperthyroid sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198867"} {"pmid": "4198868", "title": "Spontaneous firing patterns of epileptic neurons in the monkey motor cortex.", "content": "Spontaneous firing patterns of epileptic neurons in the monkey motor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198868"} {"pmid": "4198869", "title": "Behavioral impairment in the monkey following implantation of aluminum hydroxide on the temporal cortex: the role of cortical destruction.", "content": "Behavioral impairment in the monkey following implantation of aluminum hydroxide on the temporal cortex: the role of cortical destruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198869"} {"pmid": "4198870", "title": "Responses of single neurons in the auditory cortex of squirrel monkeys to variants of a single call type.", "content": "Responses of single neurons in the auditory cortex of squirrel monkeys to variants of a single call type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198870"} {"pmid": "4198877", "title": "Serological studies of Haemophilus influenzae. 3. The endotoxic effect of various antigen preparations and the relation between this effect and demonstrable precipitinogens.", "content": "Serological studies of Haemophilus influenzae. 3. The endotoxic effect of various antigen preparations and the relation between this effect and demonstrable precipitinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198877"} {"pmid": "4198878", "title": "Studies in immunodermatology. 3. Induction of intraepithelial lesions in monkeys by intramucosal injections of pemphigus antibodies.", "content": "Studies in immunodermatology. 3. Induction of intraepithelial lesions in monkeys by intramucosal injections of pemphigus antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198878"} {"pmid": "4198879", "title": "Cromolyn in extrinsic and intrinsic asthma.", "content": "Cromolyn in extrinsic and intrinsic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198879"} {"pmid": "4198880", "title": "Increased sensitivity to egg albumin in rats fed pristane.", "content": "Increased sensitivity to egg albumin in rats fed pristane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198880"} {"pmid": "4198881", "title": "Enzymatic cleavage of (+)citramalate into pyruvate and acetyl-CoA in Bacillus sp.", "content": "Enzymatic cleavage of (+)citramalate into pyruvate and acetyl-CoA in Bacillus sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198881"} {"pmid": "4198882", "title": "Interaction of chicken erythrocyte AMP deaminase with chelating agents.", "content": "Interaction of chicken erythrocyte AMP deaminase with chelating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198882"} {"pmid": "4198883", "title": "Spectroscopic properties of C-phycocyanin and of its alpha and beta subunits.", "content": "Spectroscopic properties of C-phycocyanin and of its alpha and beta subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198883"} {"pmid": "4198884", "title": "Reactivity of oxytyrosinase toward substrates.", "content": "Reactivity of oxytyrosinase toward substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198884"} {"pmid": "4198885", "title": "Primary structure of human fibrinogen and fibrin. II. Structural studies on NH2-terminal part of gamma chain.", "content": "Primary structure of human fibrinogen and fibrin. II. Structural studies on NH2-terminal part of gamma chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198885"} {"pmid": "4198886", "title": "Purification and properties of an extracellular polysaccharide containing amino sugars formed by Bacillus cereus.", "content": "Purification and properties of an extracellular polysaccharide containing amino sugars formed by Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198886"} {"pmid": "4198887", "title": "The application of cellulose carbonate to the preparation of water-insoluble immunoadsorbents used in the purification of antibodies to immunoglobulins.", "content": "The application of cellulose carbonate to the preparation of water-insoluble immunoadsorbents used in the purification of antibodies to immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198887"} {"pmid": "4198888", "title": "Further studies on the reaction of partial identity in quantitative immunoelectrophoretic patterns.", "content": "Further studies on the reaction of partial identity in quantitative immunoelectrophoretic patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198888"} {"pmid": "4198889", "title": "Circularity of the Bacillus subtilis chromosome and further studies on its bidirectional replication.", "content": "Circularity of the Bacillus subtilis chromosome and further studies on its bidirectional replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198889"} {"pmid": "4198890", "title": "Biochemical properties of a cephalosporin beta-lactamase from Pseudomonas aeruginosa.", "content": "Biochemical properties of a cephalosporin beta-lactamase from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198890"} {"pmid": "4198891", "title": "Endotoxemia in febrile reactions during hemodialysis.", "content": "Endotoxemia in febrile reactions during hemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198891"} {"pmid": "4198892", "title": "Preparation and characterization of mouse intestinal phospholipase.", "content": "Preparation and characterization of mouse intestinal phospholipase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198892"} {"pmid": "4198893", "title": "Lowering of serum cholesterol by intestinal bacteria in cholesterol-fed piglets.", "content": "Lowering of serum cholesterol by intestinal bacteria in cholesterol-fed piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198893"} {"pmid": "4198894", "title": "Societal and individual determinants of medical care utilization in the United States.", "content": "Societal and individual determinants of medical care utilization in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198894"} {"pmid": "4198895", "title": "Separation of small circular DNA molecules from the blue-green alga Anacystis nidulans.", "content": "Separation of small circular DNA molecules from the blue-green alga Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198895"} {"pmid": "4198896", "title": "X-ray diffraction of muscle labelled with antibody to troponin-C.", "content": "X-ray diffraction of muscle labelled with antibody to troponin-C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198896"} {"pmid": "4198903", "title": "Miniature eye movement.", "content": "Miniature eye movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198903"} {"pmid": "4198904", "title": "Slowed decay of the monkey's cone receptor potential by intense stimuli, and protection from this effect by light adaptation.", "content": "Slowed decay of the monkey's cone receptor potential by intense stimuli, and protection from this effect by light adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198904"} {"pmid": "4198907", "title": "Human leukemia, nucleic acids and viruses. Hypotheses and perspectives.", "content": "Human leukemia, nucleic acids and viruses. Hypotheses and perspectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198907"} {"pmid": "4198908", "title": "Some characteristics of the proliferative activity of erythroblasts in untreated and treated acute leukaemia.", "content": "Some characteristics of the proliferative activity of erythroblasts in untreated and treated acute leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198908"} {"pmid": "4198909", "title": "Transplantable myeloid rat leukaemia induced by 7,12-dimethylbenz(a)anthracene.", "content": "Transplantable myeloid rat leukaemia induced by 7,12-dimethylbenz(a)anthracene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198909"} {"pmid": "4198910", "title": "Acute myelomonocytic leukemia in a patient with Hodgkin's disease.", "content": "Acute myelomonocytic leukemia in a patient with Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198910"} {"pmid": "4198911", "title": "Monoclonal origin of acute transformation of chronic myelogenous leukemia. Evidence from an acquired sex chromosome mosaic.", "content": "Monoclonal origin of acute transformation of chronic myelogenous leukemia. Evidence from an acquired sex chromosome mosaic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198911"} {"pmid": "4198913", "title": "Fetal factor VIII and IX levels in early pregnancy and their significance in prenatal diagnosis.", "content": "Fetal factor VIII and IX levels in early pregnancy and their significance in prenatal diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198913"} {"pmid": "4198914", "title": "Accumulation of drugs on melanin.", "content": "Accumulation of drugs on melanin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198914"} {"pmid": "4198915", "title": "Angiographic abnormalities in the urinary bladder wall after irradiation. I. Animal experiments. II. Clinical investigation.", "content": "Angiographic abnormalities in the urinary bladder wall after irradiation. I. Animal experiments. II. Clinical investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198915"} {"pmid": "4198916", "title": "Turner syndrome with partial deletion of the X chromosome long arm.", "content": "Turner syndrome with partial deletion of the X chromosome long arm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198916"} {"pmid": "4198917", "title": "Visual sensitivity.", "content": "Visual sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198917"} {"pmid": "4198918", "title": "Perception.", "content": "Perception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198918"} {"pmid": "4198919", "title": "Basic drives.", "content": "Basic drives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198919"} {"pmid": "4198921", "title": "Role of inorganic nitrite in methaemoglobin formation after nitrate ester administration to the rat.", "content": "Role of inorganic nitrite in methaemoglobin formation after nitrate ester administration to the rat. 1. Methaemoglobin is rapidly formed during the incubation of rat red cells with inorganic nitrite, whereas ethylene glycol dinitrate at a higher concentration has little effect.2. The concentrations of blood inorganic nitrite in the rat after ethylene glycol dinitrate or glyceryl trinitrate injection can be reproduced by the infusion of nitrite. The methaemoglobin formed after ethylene glycol dinitrate or glyceryl trinitrate injection is equivalent to that produced from nitrite infusions simulating its formation from the nitrate esters.3. It is concluded that methaemoglobin arising from nitrate ester administration is formed principally by the action of the metabolite inorganic nitrite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198921"} {"pmid": "4198923", "title": "The action of Bacillus subtilis liquefying amylase on 6-deoxy-6-iodoamylose.", "content": "The action of Bacillus subtilis liquefying amylase on 6-deoxy-6-iodoamylose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198923"} {"pmid": "4198922", "title": "The effects of intravenous and intraduodenal feeding on nitrogen balance after surgery.", "content": "The effects of intravenous and intraduodenal feeding on nitrogen balance after surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198922"} {"pmid": "4198926", "title": "A genetic scheme for the blood systems ABO, Rh and MNSs, and an explanation of antigen-antibody patterns.", "content": "A genetic scheme for the blood systems ABO, Rh and MNSs, and an explanation of antigen-antibody patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198926"} {"pmid": "4198925", "title": "Iron metabolism of premature infants and their mothers.", "content": "Iron metabolism of premature infants and their mothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198925"} {"pmid": "4198927", "title": "The effect on reaction to painful stimuli of lesions in the centromedian nucleus in the thalamus of the monkey.", "content": "The effect on reaction to painful stimuli of lesions in the centromedian nucleus in the thalamus of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198927"} {"pmid": "4198928", "title": "The surgical production of chronic uremia in primates.", "content": "The surgical production of chronic uremia in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198928"} {"pmid": "4198930", "title": "Alpha-D-fucosidase from Aspergillus oryzae: characterization of alpha-D-fucosidase with alpha-D-galactosidase activity.", "content": "Alpha-D-fucosidase from Aspergillus oryzae: characterization of alpha-D-fucosidase with alpha-D-galactosidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198930"} {"pmid": "4198929", "title": "Na+-dependent transport of threonine in Brevibacterium flavum.", "content": "Na+-dependent transport of threonine in Brevibacterium flavum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198929"} {"pmid": "4198931", "title": "A mathematical model for the determination of viscoelastic behavior of brain in vivo. II. Relaxation response.", "content": "A mathematical model for the determination of viscoelastic behavior of brain in vivo. II. Relaxation response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198931"} {"pmid": "4198932", "title": "Studies of Ternidens deminutus Railliet & Henry, 1909 (Nematoda). I. External morphology.", "content": "Studies of Ternidens deminutus Railliet & Henry, 1909 (Nematoda). I. External morphology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198932"} {"pmid": "4198933", "title": "High voltage electron microscopy of cellular changes in the wet state.", "content": "High voltage electron microscopy of cellular changes in the wet state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198933"} {"pmid": "4198934", "title": "Resynchronization of RNA synthesis by coliphage Qbeta replicase at an internal site of the RNA template.", "content": "Resynchronization of RNA synthesis by coliphage Qbeta replicase at an internal site of the RNA template.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198934"} {"pmid": "4198935", "title": "A common conformational feature in several prokaryotic and eukaryotic 5 S RNAs: a highly exposed, single-stranded loop around position 40.", "content": "A common conformational feature in several prokaryotic and eukaryotic 5 S RNAs: a highly exposed, single-stranded loop around position 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198935"} {"pmid": "4198936", "title": "The quantitative histochemistry of acid proteinase in the nervous system: localization in neurons.", "content": "The quantitative histochemistry of acid proteinase in the nervous system: localization in neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198936"} {"pmid": "4198938", "title": "Cost-benefit analysis of in vitro screening tests of thyroid function.", "content": "Cost-benefit analysis of in vitro screening tests of thyroid function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198938"} {"pmid": "4198939", "title": "Retreatment of recurrent nasopharyngeal malignancy using a radium mold.", "content": "Retreatment of recurrent nasopharyngeal malignancy using a radium mold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198939"} {"pmid": "4198940", "title": "Prevention of infection of pacemaker pocket.", "content": "Prevention of infection of pacemaker pocket.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198940"} {"pmid": "4198937", "title": "Experimental comparison of radioactive agents for studies of the placenta.", "content": "Experimental comparison of radioactive agents for studies of the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198937"} {"pmid": "4198945", "title": "Urinary antidiuretic hormone excretion during the menstrual cycle and pregnancy in the monkey.", "content": "Urinary antidiuretic hormone excretion during the menstrual cycle and pregnancy in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198945"} {"pmid": "4198949", "title": "The nurse and the high-risk infant.", "content": "The nurse and the high-risk infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198949"} {"pmid": "4198950", "title": "Total intravenous nutrition by peripheral vein in neonatal surgical patients.", "content": "Total intravenous nutrition by peripheral vein in neonatal surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198950"} {"pmid": "4198952", "title": "Kinetic analysis of the base sequence heterogeneity of RNA molecules by RNA-DNA hybridization.", "content": "Kinetic analysis of the base sequence heterogeneity of RNA molecules by RNA-DNA hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198952"} {"pmid": "4198951", "title": "Studies of the sudden infant death syndrome in King County, Washington. IV. Immunologic studies.", "content": "Studies of the sudden infant death syndrome in King County, Washington. IV. Immunologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198951"} {"pmid": "4198954", "title": "Role of the skin in amphibian sodium metabolism.", "content": "Role of the skin in amphibian sodium metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198954"} {"pmid": "4198953", "title": "Hybridization of nucleic acids to chromosomes.", "content": "Hybridization of nucleic acids to chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198953"} {"pmid": "4198955", "title": "Some aspects of respiratory function in three siblings with Morquio-Brailsford disease.", "content": "Some aspects of respiratory function in three siblings with Morquio-Brailsford disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198955"} {"pmid": "4198956", "title": "Qualitative and quantitative comparison of C3 variant sera during the Bonn workshop.", "content": "Qualitative and quantitative comparison of C3 variant sera during the Bonn workshop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198956"} {"pmid": "4198957", "title": "Haemolytic disease of the newborn caused by the rare Rhesus antibody anti-CX.", "content": "Haemolytic disease of the newborn caused by the rare Rhesus antibody anti-CX.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198957"} {"pmid": "4198958", "title": "Immunological dosage of Hb F and its correlation with the Singer test. Decrease of fetal hemoglobin with age.", "content": "Immunological dosage of Hb F and its correlation with the Singer test. Decrease of fetal hemoglobin with age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198958"} {"pmid": "4198959", "title": "Report of a proficiency test for the hepatitis-B antigen.", "content": "Report of a proficiency test for the hepatitis-B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198959"} {"pmid": "4198961", "title": "An improved automated method for the estimation of sialic acid released in the neuraminidase assay.", "content": "An improved automated method for the estimation of sialic acid released in the neuraminidase assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198961"} {"pmid": "4198962", "title": "Substrate specificity of a human-specific esterase.", "content": "Substrate specificity of a human-specific esterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198962"} {"pmid": "4198963", "title": "Immunodiffusion reaction with animal influenza viruses and antibody.", "content": "Immunodiffusion reaction with animal influenza viruses and antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198963"} {"pmid": "4198969", "title": "The disorder of hyaluronic acid metabolism in cultured skin fibroblasts derived from a patient with the Hurler syndrome.", "content": "The disorder of hyaluronic acid metabolism in cultured skin fibroblasts derived from a patient with the Hurler syndrome. The metabolism of hyaluronic acid in cultured skin fibroblasts derived from a patient with the Hurler syndrome and from a normal subject was examined. 1. An increased net incorporation of [(3)H]glucose into the hyaluronic acid fraction of the Hurler-syndrome cells occurred when compared with normal cells. 2. During a ;chase' period, approx. 35% of the radioactivity derived from glucose was lost from the hyaluronic acid fraction of the Hurler-syndrome cells, whereas the normal cells retained all their radioactivity. 3. Although the Hurler-syndrome cells contained a ninefold greater amount of hyaluronic acid than normal cells, simultaneous determination of the specific radioactivity derived from the label revealed a value for the Hurler-syndrome cells one-half that of normal cells. These results are taken to indicate that the Hurler cells synthesize hyaluronic acid de novo at a higher rate than do normal cells. 4. Exposure of Hurler-syndrome cultured fibroblasts to a crude urine corrective-factor preparation (Neufeld & Cantz, 1971), now known to contain alpha-l-iduronidase, the specific Hurler-syndrome corrective factor (Bach et al., 1972), decreased the hyaluronic acid content to near-normal values before any effect was observed on [(3)H]glucose incorporation into the hyaluronic acid fraction. 5. In addition, the hyaluronic acid content of the normal cells decreased after exposure to the corrective factor of urine. 6. The mobilization of hyaluronic acid in Hurler-syndrome and normal cells exposed to the crude corrective-factor preparation of urine caused a decrease in specific radioactivity in the ;corrected' Hurler-syndrome cells and an increase in specific radioactivity in the ;corrected' normal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198969"} {"pmid": "4198970", "title": "Isolation and characterization of membrane-bound polysomes from ascites tumor cells.", "content": "Isolation and characterization of membrane-bound polysomes from ascites tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198970"} {"pmid": "4198972", "title": "ATP regeneration using immobilized carbamyl phosphokinase.", "content": "ATP regeneration using immobilized carbamyl phosphokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198972"} {"pmid": "4198973", "title": "Immunochemical characterization of commercial protease products.", "content": "Immunochemical characterization of commercial protease products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198973"} {"pmid": "4198974", "title": "Differences in the urea-extracted proteins of mouse epidermis and squamous cell carcinomata determined by fluorescence microscopy.", "content": "Differences in the urea-extracted proteins of mouse epidermis and squamous cell carcinomata determined by fluorescence microscopy. Fluorescence microscopy was used to demonstrate differences in the urea-extractable antigens of mouse epidermis and squamous cell carcinoma. When serum- and normal tissue sediment-absorbed antisera prepared against mouse epidermal urea-extracted proteins were further absorbed with carcinoma urea antigens, antisera specific for epidermis resulted. When antisera raised against the urea-extractable proteins of mouse squamous cell carcinomata were serum- and normal tissue sediment-absorbed and then further absorbed with epidermal urea antigens, antisera were prepared which stained papilloma and carcinoma, but not epidermis, and thus these antisera were not specific for carcinoma. Antisera prepared against the urea-extractable proteins of human epidermis reacted in immunodiffusion in agar with the epidermal urea proteins, but not with human squamous cell carcinoma urea proteins. Also antisera prepared against the carcinoma urea-extractable proteins reacted with these proteins in agar, but no reaction occurred with the epidermal urea-extractable proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198974"} {"pmid": "4198975", "title": "Mechanisms of selective uptake of 2-methyl-4-naphthoquinol bis disodium phosphate, into some mammalian cells in tissue culture.", "content": "Mechanisms of selective uptake of 2-methyl-4-naphthoquinol bis disodium phosphate, into some mammalian cells in tissue culture. Earlier papers have described the selective uptake of the radioactive drug 2-methyl 6,7-ditritio-1, 4-naphthoquinol bis disodium phosphate into some human tumour cells in tissue culture. This work examines these results in greater detail. The kinetics of the uptake process into HEp/2 cells and its precise dependence on the experimental conditions are described. It is shown that an alkaline phosphatase (APase) is present on the surface of HEp/2 cells and that this is responsible for the uptake of label. L cells do not take up the radioactive label and are shown not to possess significant quantities of APase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198975"} {"pmid": "4198981", "title": "Metabolic effects of PCB (polychlorinated biphenyls) on the brown trout (Salmo trutta).", "content": "Metabolic effects of PCB (polychlorinated biphenyls) on the brown trout (Salmo trutta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198981"} {"pmid": "4198982", "title": "Free radical mechanism for phenylhydrazine action on the retractor unguis muscle of the grasshopper, Romalea microptera.", "content": "Free radical mechanism for phenylhydrazine action on the retractor unguis muscle of the grasshopper, Romalea microptera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198982"} {"pmid": "4198983", "title": "Vorticella--a model for chemopharmacodynamic action on smooth muscle.", "content": "Vorticella--a model for chemopharmacodynamic action on smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198983"} {"pmid": "4198984", "title": "The relationship between total body potassium and exchangeable body potassium measured at 24 hours and 44 hours after administration of 43K.", "content": "The relationship between total body potassium and exchangeable body potassium measured at 24 hours and 44 hours after administration of 43K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198984"} {"pmid": "4198985", "title": "Sympathetic innervation of the ciliary muscle in monkeys.", "content": "Sympathetic innervation of the ciliary muscle in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198985"} {"pmid": "4198987", "title": "Pattern of recruitment of oocytes to second growth phase in normal toads, and in hypophysectomized toads, Bufo bufo bufo (L.), treated with gonadotropin (HCG).", "content": "Pattern of recruitment of oocytes to second growth phase in normal toads, and in hypophysectomized toads, Bufo bufo bufo (L.), treated with gonadotropin (HCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198987"} {"pmid": "4198986", "title": "The effect of lipids from Listeria monocytogenes on immune response in mice.", "content": "The effect of lipids from Listeria monocytogenes on immune response in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198986"} {"pmid": "4198989", "title": "The immunoglobulins derived from a VH-CH recombinant rabbit and its normal relatives. I. Measurements of heavy chain molecular weights and allotypes of colostral IgA.", "content": "The immunoglobulins derived from a VH-CH recombinant rabbit and its normal relatives. I. Measurements of heavy chain molecular weights and allotypes of colostral IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198989"} {"pmid": "4198991", "title": "Plasmocid encephalopathy in the rhesus monkey: a study of selective vulnerability.", "content": "Plasmocid encephalopathy in the rhesus monkey: a study of selective vulnerability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198991"} {"pmid": "4198992", "title": "Prostaglandin E2 and gastric acid secretion in man.", "content": "Prostaglandin E2 and gastric acid secretion in man. 1. Extracts of human stomach homogenized in Krebs solution had more PGE(2)-like activity than tissue homogenized in acid/ethanol or in the presence of indomethacin, indicating that the tissue can synthesize PGE(2).2. The distribution and synthesis of PGE(2)-like substance in human stomach was determined by extracting frozen sections cut parallel to the mucosal surface. Peak levels usually occurred at a depth of 0-600 mum in the mucosa.3. Small amounts of a PGE(2)-like substance were present in basal gastric juice, and its concentration was usually even lower in secretion stimulated by pentagastrin or histamine.4. Submaximal acid secretion produced by I.V. infusion of pentagastrin generally fell slightly when indomethacin was administered rectally to inhibit PG synthesis.5. These experiments, together with the findings that orally administered PGE compounds do not inhibit human gastric acid secretion, seem to argue against a possible inhibitory role for PGE(2) in gastric acid secretion in man.6. If this is so, it would follow that gastric bleeding caused by aspirin-like drugs is not due to increased acid secretion. A hypothesis is presented that tissue damage following vasoconstriction and ischaemia, due to inhibition of PG synthesis in blood vessels, contributes to the bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198992"} {"pmid": "4198993", "title": "The dangers of oral feeding in the presence of cuffed tracheostomy tubes.", "content": "The dangers of oral feeding in the presence of cuffed tracheostomy tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198993"} {"pmid": "4198995", "title": "Ultrastructure and functional states of mitochondria. Effect of fixatives on the stabilization of unstable configuration.", "content": "Ultrastructure and functional states of mitochondria. Effect of fixatives on the stabilization of unstable configuration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198995"} {"pmid": "4198996", "title": "Reversibly temperature sensitive phototransduction mutant of Drosophila melanogaster.", "content": "Reversibly temperature sensitive phototransduction mutant of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198996"} {"pmid": "4198998", "title": "Neurofibromatosis (Von Recklinghausen's disease) and juxta-medullary spinal lipoma.", "content": "Neurofibromatosis (Von Recklinghausen's disease) and juxta-medullary spinal lipoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198998"} {"pmid": "4198990", "title": "Cortical bone remodeling and bone mass in primary osteoarthrosis of the hip.", "content": "Cortical bone remodeling and bone mass in primary osteoarthrosis of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198990"} {"pmid": "4198999", "title": "Contributions to the optimal use of human blood. II. The large-scale preparation of prothrombin complex. A comparison between two methods using the anion exchangers DEAE-cellulose DE 52 and DEAE-sephadex A-50.", "content": "Contributions to the optimal use of human blood. II. The large-scale preparation of prothrombin complex. A comparison between two methods using the anion exchangers DEAE-cellulose DE 52 and DEAE-sephadex A-50.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4198999"} {"pmid": "4199000", "title": "The presence of I, H, HI, and i blood group substances in the tissues of rabbits, monkeys, and guinea pigs.", "content": "The presence of I, H, HI, and i blood group substances in the tissues of rabbits, monkeys, and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199000"} {"pmid": "4199001", "title": "Glycogen synthesis in rat diaphragm in vivo: a biphasic effect of insulin on glycogen synthetase enzyme.", "content": "Glycogen synthesis in rat diaphragm in vivo: a biphasic effect of insulin on glycogen synthetase enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199001"} {"pmid": "4199002", "title": "Adenohypophysial growth and thyroxine binding: effects of steroid hormones.", "content": "Adenohypophysial growth and thyroxine binding: effects of steroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199002"} {"pmid": "4199004", "title": "Agenesis of the corpus callosum in the median facial cleft syndrome and associated ocular malformations.", "content": "Agenesis of the corpus callosum in the median facial cleft syndrome and associated ocular malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199004"} {"pmid": "4199003", "title": "The epidemiology of hepatitis B infections in Africa: results of a pilot survey in the Republic of Senegal.", "content": "The epidemiology of hepatitis B infections in Africa: results of a pilot survey in the Republic of Senegal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199003"} {"pmid": "4199005", "title": "Ocular abnormalities of a child associated with familial microcephaly.", "content": "Ocular abnormalities of a child associated with familial microcephaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199005"} {"pmid": "4199006", "title": "Formaldehyde-glutaraldehyde fixation.", "content": "Formaldehyde-glutaraldehyde fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199006"} {"pmid": "4199007", "title": "Tissue response to the movement of bones.", "content": "Tissue response to the movement of bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199007"} {"pmid": "4199008", "title": "Faciolingual tooth movement: its influence on the root and cortical plate.", "content": "Faciolingual tooth movement: its influence on the root and cortical plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199008"} {"pmid": "4199013", "title": "The uptake of 2-deoxy-D-glucose by Pseudomonas aeruginosa and its regulation.", "content": "The uptake of 2-deoxy-D-glucose by Pseudomonas aeruginosa and its regulation. The non-metabolizable glucose analogue 2-deoxy-d-glucose is taken up by Pseudomonas aeruginosa against a concentration gradient, in a predominantly unchanged form. d-Glucose competitively inhibits 2-deoxy-d-glucose uptake and also causes a rapid exit of intracellular 2-deoxy-d-glucose. Thus these two sugars share the same stereospecific carrier system, and glucose transport can be studied reliably with 2-deoxy-d-glucose. The transport system is inducible, and is strongly repressed by a number of organic acids such as acetate, citrate, succinate, fumarate and malate, even in the presence of adequate excess of the inducer (d-glucose). Repression by organic acids can be relieved by transferring cells to a glucose medium, but in the presence of chloramphenicol the cells fail to recover from repression, indicating that the formation of the transport system involves the synthesis of protein. The results demonstrate that the regulation of glucose metabolism effected by citric acid-cycle intermediates in P. aeruginosa is manifest at the level of the glucose-transport system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199013"} {"pmid": "4199011", "title": "Chemostat studies on the regulation of glucose metabolism in Pseudomonas aeruginosa by citrate.", "content": "Chemostat studies on the regulation of glucose metabolism in Pseudomonas aeruginosa by citrate. The effect of the relative concentrations of citrate and glucose on the regulation of key enzymes of the direct oxidative, phosphorylative, Entner-Doudoroff and pentose-cycle pathways of glucose metabolism in Pseudomonas aeruginosa has been investigated in continuous culture under conditions of NH(4) (+)-limitation. For comparison isocitrate dehydrogenase and aconitase were also assayed. Measurements were made for steady-state and transient conditions and the effect of growth rate was also studied. When cells grew on 75mm-citrate the glucose concentration had to attain 6-8mm before significant induction of enzymes of glucose metabolism occurred; the specific activities increased further as the result of both raising the glucose concentration to 30mm and then subsequently lowering the citrate to 60mm and then to 45mm. The specific activities of the glucose enzymes increased immediately during the transient period between the steady states characteristic of growth on 6mm- and 8mm-glucose, the increase continuing for about two doubling times. The converse experiment of adding increasing citrate concentrations to 45mm-glucose medium revealed an immediate induction of the citrate-transport system, oxidation of citrate following the increase in citrate concentration up to 8mm. Between 8mm- and 16mm-citrate a marked repression of gluconate, glucose 6-phosphate and 6-phosphogluconate dehydrogenases and the Entner-Doudoroff enzymes occurred. Increased growth rate in citrate medium resulted in decreased specific activities of glucose 6-phosphate dehydrogenase and isocitrate dehydrogenase. Increased growth rate in citrate-glucose medium gave decreased specific activities of isocitrate dehydrogenase and aconitase whereas the activities of some of the glucose enzymes decreased initially but then increased at the highest growth rate (0.5h(-1)), at which a marked increase in glucose utilization occurred. These observations accord with the regulation of glucose enzymes by induction with glucose or its metabolites and repression by citrate or its metabolic products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199011"} {"pmid": "4199012", "title": "The regulation of transport of glucose and methyl alpha-glucoside in Pseudomonas aeruginosa.", "content": "The regulation of transport of glucose and methyl alpha-glucoside in Pseudomonas aeruginosa. The methyl alpha-glucoside-transport system of Pseudomonas aeruginosa has been characterized with respect to its specificity, energy-dependence, kinetics and regulation. The uptake of glucose involved two components, one of which transported glucose (K(m)=8mum) and methyl alpha-glucoside (K(m)=2.8mm) whereas the other was more complex, involving the extracellular activity of glucose dehydrogenase. Mutants defective in this enzyme have been isolated and characterized. The methyl alpha-glucoside-glucose-transport system was repressed when the organism was grown in the absence of glucose; the induction of this transport system by glucose, and its activity once induced, were inhibited by products of citrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199012"} {"pmid": "4199014", "title": "Interrelationship of islet metabolism, adenosine triphosphate content and insulin release.", "content": "Interrelationship of islet metabolism, adenosine triphosphate content and insulin release. The oxidation of some exogenous substrates and their effects on ATP content and insulin release in mouse pancreatic islets were measured. The ATP concentration of islets incubated without exogenous substrate shows a gradual decrease, which can be prevented by glucose or mannose (20mm) or leucine (2.5mm); d-glyceraldehyde (5mm) is as effective as glucose (5mm); fructose or N-acetylglucosamine (20mm), pyruvate (10mm) and dl-3-hydroxybutyrate (2mm) are less effective; galactose (20mm), acetate (10mm), octanoate (2mm) and succinate (10mm) have no ATP-maintaining ability. Islets oxidize glucose, mannose, glyceraldehyde, leucine and, less readily, N-acetylglucosamine and glucosamine; galactose, however, is poorly metabolized. Mannoheptulose inhibits the oxidation of glucose but not of glyceraldehyde. Insulin release, measured over a 2h incubation, is stimulated by glucose, mannose, leucine, glyceraldehyde or glucosamine but not by fructose or N-acetylglucosamine. The latter, however, potentiates the effects of glucose or glyceraldehyde (5mm) or leucine (2.5mm) on release; the potentiating effects are inhibited by mannoheptulose, which also blocks glucose-, but not glyceraldehyde- or leucine-stimulated release. In the presence of glucose (20mm), metabolic inhibitors depress insulin release and islet ATP content in parallel. However, rates of insulin release and ATP content measured after incubation with various combinations of exogenous substrates do not appear to be correlated. Sulphonylureas stimulate insulin release but decrease islet ATP concentrations. These results provide further evidence of a close association between the metabolic activity of exogenous substrates and their ability to initiate insulin release. Glucoreceptor models are formulated in the light of these observations and discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199014"} {"pmid": "4199024", "title": "Toxicologic and pharmacologic aspects of rifampin.", "content": "Toxicologic and pharmacologic aspects of rifampin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199024"} {"pmid": "4199027", "title": "Influence of insulin and glybenclamid on the intestinal disaccharidases of subtotally pancreatectomized rats.", "content": "Influence of insulin and glybenclamid on the intestinal disaccharidases of subtotally pancreatectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199027"} {"pmid": "4199026", "title": "Effect of protein-calorie malnutrition on the development of social behavior in rats.", "content": "Effect of protein-calorie malnutrition on the development of social behavior in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199026"} {"pmid": "4199031", "title": "Mandibular bone grafting in trauma.", "content": "Mandibular bone grafting in trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199031"} {"pmid": "4199032", "title": "Injuries of the face and jaws in children.", "content": "Injuries of the face and jaws in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199032"} {"pmid": "4199033", "title": "A technique of vestibular plasty using a free mucosal graft from the cheek.", "content": "A technique of vestibular plasty using a free mucosal graft from the cheek.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199033"} {"pmid": "4199034", "title": "Reversibility of surgically induced dental ankylosis in rats.", "content": "Reversibility of surgically induced dental ankylosis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199034"} {"pmid": "4199035", "title": "Serum IgD concentrations in children with atopic diseases.", "content": "Serum IgD concentrations in children with atopic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199035"} {"pmid": "4199036", "title": "Neutral sucrose sedimentation of very large DNA from Bacillus subtilis. I. Effect of random double-strand breaks and centrifuge speed on sedimentation.", "content": "Neutral sucrose sedimentation of very large DNA from Bacillus subtilis. I. Effect of random double-strand breaks and centrifuge speed on sedimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199036"} {"pmid": "4199037", "title": "Neutral sucrose gradient sedimentation of very large DNA from Bacillus subtilis. II. Double-strand breaks formed by gamma ray irradiation of the cells.", "content": "Neutral sucrose gradient sedimentation of very large DNA from Bacillus subtilis. II. Double-strand breaks formed by gamma ray irradiation of the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199037"} {"pmid": "4199038", "title": "Relation between single-strand DNA mass and sedimentation distance in alkaline sucrose gradients.", "content": "Relation between single-strand DNA mass and sedimentation distance in alkaline sucrose gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199038"} {"pmid": "4199041", "title": "Intravenously induced infantile intoxication with ethanol.", "content": "Intravenously induced infantile intoxication with ethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199041"} {"pmid": "4199040", "title": "Hypothalamic gigantism.", "content": "Hypothalamic gigantism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199040"} {"pmid": "4199042", "title": "Pigmented lesions of incontinentia pigmenti in a neonate.", "content": "Pigmented lesions of incontinentia pigmenti in a neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199042"} {"pmid": "4199043", "title": "Synthesis of (plus-)-trans-11-methylthio-1,2,3,4,6,7,12,12b-octahydrohydroxyindolo(2,3-a)quinolizine.", "content": "Synthesis of (plus-)-trans-11-methylthio-1,2,3,4,6,7,12,12b-octahydrohydroxyindolo(2,3-a)quinolizine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199043"} {"pmid": "4199044", "title": "Antigenicity of vascular heterografts.", "content": "Antigenicity of vascular heterografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199044"} {"pmid": "4199046", "title": "Studies on the primitive lymphatic apparatus in the blood vascular system of the lungs of Macaca cyclopis.", "content": "Studies on the primitive lymphatic apparatus in the blood vascular system of the lungs of Macaca cyclopis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199046"} {"pmid": "4199047", "title": "The M. temporalis of the Formosan monkey.", "content": "The M. temporalis of the Formosan monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199047"} {"pmid": "4199048", "title": "The failing blade-vent implant.", "content": "The failing blade-vent implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199048"} {"pmid": "4199050", "title": "Isolation and partial characterization of arachin-P6.", "content": "Isolation and partial characterization of arachin-P6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199050"} {"pmid": "4199049", "title": "Isolation of the teichoic acid of Bacillus subtilis 168 by affinity chromatography.", "content": "Isolation of the teichoic acid of Bacillus subtilis 168 by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199049"} {"pmid": "4199054", "title": "Toxicity of systemic insecticides. Toxicological considerations in using of ganophosphorus insecticides.", "content": "Toxicity of systemic insecticides. Toxicological considerations in using of ganophosphorus insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199054"} {"pmid": "4199055", "title": "Lean diets and atherosclerosis.", "content": "Lean diets and atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199055"} {"pmid": "4199053", "title": "Effects of immunizing turkeys with ovine luteinizing hormone.", "content": "Effects of immunizing turkeys with ovine luteinizing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199053"} {"pmid": "4199056", "title": "Treatment and prevention of childhood lead poisoning: new approach.", "content": "Treatment and prevention of childhood lead poisoning: new approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199056"} {"pmid": "4199057", "title": "Bioavailability studies of nitrates in the dog.", "content": "Bioavailability studies of nitrates in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199057"} {"pmid": "4199058", "title": "The metabolism of 5,5-diphenylhydantoin (DPH) in nonpregnant and pregnant Rhesus monkeys.", "content": "The metabolism of 5,5-diphenylhydantoin (DPH) in nonpregnant and pregnant Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199058"} {"pmid": "4199083", "title": "Studies on acute phase proteins of rat serum. 3. Site of synthesis of albumin and alpha 1-acid glycoprotein and the contents of these proteins in liver microsome fractions from rats suffering from induced inflammation.", "content": "Studies on acute phase proteins of rat serum. 3. Site of synthesis of albumin and alpha 1-acid glycoprotein and the contents of these proteins in liver microsome fractions from rats suffering from induced inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199083"} {"pmid": "4199084", "title": "The amino acid sequence of Streptomyces griseus trypsin. I. The peptic peptides.", "content": "The amino acid sequence of Streptomyces griseus trypsin. I. The peptic peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199084"} {"pmid": "4199085", "title": "Variations in genetic architecture at different doses of gamma-radiation as measured by longevity in Drosophila melanogaster.", "content": "Variations in genetic architecture at different doses of gamma-radiation as measured by longevity in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199085"} {"pmid": "4199086", "title": "The principal liver carcinogen-protein conjugate after a single dose of hepatic azocarcinogen.", "content": "The principal liver carcinogen-protein conjugate after a single dose of hepatic azocarcinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199086"} {"pmid": "4199087", "title": "Immunochemical studies on lactate dehydrogenase: preparation and characterization of anti-M lactate dehydrogenase antiserum: development of an immunochemical assay for lactate dehydrogenase isoenzymes in human serum.", "content": "Immunochemical studies on lactate dehydrogenase: preparation and characterization of anti-M lactate dehydrogenase antiserum: development of an immunochemical assay for lactate dehydrogenase isoenzymes in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199087"} {"pmid": "4199088", "title": "Quantitation of human IgG by rocket immunoelectrophoresis at pH 5 by use of carbamylated antibodies. A routine laboratory method.", "content": "Quantitation of human IgG by rocket immunoelectrophoresis at pH 5 by use of carbamylated antibodies. A routine laboratory method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199088"} {"pmid": "4199089", "title": "Serum immunoglobulins, complement component levels and autoantibodies in liver disease.", "content": "Serum immunoglobulins, complement component levels and autoantibodies in liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199089"} {"pmid": "4199091", "title": "Immunoglobulin alterations associated with heroin addiction.", "content": "Immunoglobulin alterations associated with heroin addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199091"} {"pmid": "4199090", "title": "Immunological studies in children undergoing tonsillectomy.", "content": "Immunological studies in children undergoing tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199090"} {"pmid": "4199094", "title": "Anti-chromium barrier creams.", "content": "Anti-chromium barrier creams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199094"} {"pmid": "4199095", "title": "Factors affecting care of the patient: clients, government policy, role of the family and social attitudes.", "content": "Factors affecting care of the patient: clients, government policy, role of the family and social attitudes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199095"} {"pmid": "4199096", "title": "Effect of aging on the marmoset periodontium.", "content": "Effect of aging on the marmoset periodontium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199096"} {"pmid": "4199093", "title": "Some factors affecting precipitation and complex formation of an IgG cryoglobulin.", "content": "Some factors affecting precipitation and complex formation of an IgG cryoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199093"} {"pmid": "4199092", "title": "In vitro synthesis of immunoglobulins, secretory component and complement in normal and pathological skin and the adjacent mucous membranes.", "content": "In vitro synthesis of immunoglobulins, secretory component and complement in normal and pathological skin and the adjacent mucous membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199092"} {"pmid": "4199097", "title": "Verrucous carcinoma of the mouth.", "content": "Verrucous carcinoma of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199097"} {"pmid": "4199098", "title": "Familial gingival fibromatosis: an unusual pathology.", "content": "Familial gingival fibromatosis: an unusual pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199098"} {"pmid": "4199099", "title": "Mitostatic action of vinblastine sulphate on oral epithelia of hamsters.", "content": "Mitostatic action of vinblastine sulphate on oral epithelia of hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199099"} {"pmid": "4199100", "title": "Changes in cell cycle characteristics in hamster cheek pouch epithelium during treatment with DMBA.", "content": "Changes in cell cycle characteristics in hamster cheek pouch epithelium during treatment with DMBA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199100"} {"pmid": "4199102", "title": "Scanning electron microscopy of calcium hydroxide induced bridges.", "content": "Scanning electron microscopy of calcium hydroxide induced bridges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199102"} {"pmid": "4199101", "title": "Fibrous dysplasia: a nosologic problem in the diagnosis of fibro-osseous lesions of the jaws.", "content": "Fibrous dysplasia: a nosologic problem in the diagnosis of fibro-osseous lesions of the jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199101"} {"pmid": "4199105", "title": "Isolation and properties of Bacillus subtilis strains lysogenized by a clear plaque mutant of bacteriophage phi 105.", "content": "Isolation and properties of Bacillus subtilis strains lysogenized by a clear plaque mutant of bacteriophage phi 105. A clear plaque mutant of the temperate Bacillus phage phi105 lysogenized a small fraction of infected cells forming an integrated prophage at or near the normal phi105 insertion site. These lysogens exhibited a spontaneous induction rate approximately 1,000-fold lower than wild type and were noninducible (ind(-)) by mitomycin C. Prophage was induced, however, when competent cultures were incubated with transforming DNA. The ind(-) phenotype could not be attributed solely to the clear plaque mutation and appears to involve a cell-specific factor. Lysogenization by the clear plaque mutant, in contrast to wild-type phage, did not cause a marked reduction in transformation efficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199105"} {"pmid": "4199106", "title": "DNA-mediated prophage induction in Bacillus subtilis lysogenic for phi 105c4.", "content": "DNA-mediated prophage induction in Bacillus subtilis lysogenic for phi 105c4. Prophage was induced when strains of Bacillus subtilis 168 lysogenic for phi105c4 were grown to competence and exposed to specific bacterial DNAs. The time course of phage production was similar to that observed for mitomycin C induction of wild-type prophage. Induction was directly dependent upon DNA concentration up to levels which were saturating for the transformation of bacterial auxotrophic markers. The extent of induction varied with the source of DNA. The burst of phage induced by DNA isolated from a W23 strain of B. subtilis was fivefold less than that induced by DNA from B. subtilis 168 strains, while B. licheniformis DNA was completely inactive. This order of inducing activity was correlated with the ability of the respective DNAs to transform auxotrophic markers carried by one of the phi105c4 lysogens. Differences in inducing activity also were observed for different forms of phi105 DNA. The DNAs isolated from phi105 phage particles and phi105c4 lysogens were inactive, whereas DNA from cells lysogenized by wild-type phi105 induced a burst of phage. When tested for transforming activity, however, both phi105c4 and phi105 lysogen DNAs were equally effective. An induction mechanism which involves recombination at the prophage insertion site is proposed to explain these differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199106"} {"pmid": "4199108", "title": "Synthesis of bacteriophage phi 29 proteins in Bacillus subtilis.", "content": "Synthesis of bacteriophage phi 29 proteins in Bacillus subtilis. Seventeen bacteriophage phi29 proteins were detected in ultraviolet light-irradiated Bacillus subtilis by autoradiography of polyacrylamide slab gels. The appearance of phi29 proteins occurred either before or concomitantly with viral DNA replication. Viral proteins detected early in the infectious cycle consisted of nine polypeptides ranging from 5,200 daltons to 54,000 daltons. Two of the early proteins were identified as, respectively, the major capsid protein and the protein comprising the filaments which extend from the head of the virus. Late phi29 proteins were composed of eight polypeptides ranging from 14,000 daltons to 95,000 daltons. Only three late proteins were noncapsid proteins. Among the early proteins, six were synthesized at diminishing rates late in the infectious cycle. One of the early proteins (protein 12) lacked histidine, whereas two (proteins 10 and 15) lacked tryptophan. Among the 17 proteins detected, 10 were viral noncapsid proteins. The amount of viral genetic information required to code for the 17 proteins detected in these experiments (81% of the potential genetic information of phi29 DNA) compares favorably with the genetic information detected as mRNA in a previous report, 85% of the potential information on the phi29 chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199108"} {"pmid": "4199107", "title": "Effects of actinomycin D and ultraviolet and ionizing radiation on Pichinde virus.", "content": "Effects of actinomycin D and ultraviolet and ionizing radiation on Pichinde virus. Actinomycin D (0.05 mug/ml) suppresses the synthesis of ribosomal RNA of baby hamster kidney (BHK21) cells. The production of infectious Pichinde virus was enhanced in the presence of actinomycin D, although the production of virus particles was not substantially different from cultures inoculated in the absence of the drug. By prelabeling BHK21 cells with (3)H-uridine and then allowing the virus to replicate in the presence of actinomycin D, it was possible to show that ribosomal RNA synthesized prior to infection was incorporated into the virion. A single-hit kinetics of inactivation of Pichinde virus was observed with ultraviolet light, suggesting that the virus contains only a single copy of genome per virion. Comparison of the inactivation kinetics by gamma irradiation of Pichinde virus with Sindbis and rubella virus indicated that the radiosensitive genome of Pichinde virus was about 6 x 10(6) to 8 x 10(6) daltons. This value is greater than the 3.2 x 10(6) daltons which was estimated by biochemical analysis. One possible explanation considered is that the ribosomal RNA of host cell origin is functional and accounts for the differences in genome size estimated by the two methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199107"} {"pmid": "4199109", "title": "Heat induction of prophage phi 105 in Bacillus subtilis: bacteriophage-induced bidirectional replication of the bacterial chromosome.", "content": "Heat induction of prophage phi 105 in Bacillus subtilis: bacteriophage-induced bidirectional replication of the bacterial chromosome. A mutant of Bacillus subtilis, dna-1, which cannot initiate new rounds of DNA replication (obtained from N. Sueoka) was lysogenized with wild-type phi 105 and with the heat-inducible mutant phi 105 cts23. Bacteria were incubated at the permissive temperature in the presence of chloramphenicol and then shifted to the nonpermissive temperature where induction of phi 105 cts23 occurs. DNA made after the shift was labeled with a density label, and the distribution of bacterial and phage markers in replicated and unreplicated DNA was determined. Similar experiments were performed with nonlysogenic dna-1 infected with phage phi 105 cts23 after the temperature shift. The results show that after induction of phi 105 cts23 prophage, bacterial markers on either side of the prophage replicate at an increased rate compared to more distant markers. No selective stimulation of bacterial DNA synthesis was observed on infection or after shifting bacteria lysogenic for noninducible phage to the higher temperature. Attempts to suppress the initiation mutation dna-1 by phage phi 105 were unsuccessful.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199109"} {"pmid": "4199110", "title": "A survey of mycobacterial isolates from the Randwick Chest Hospital, Sydney, in an 18-month period, 1970 to 1971.", "content": "A survey of mycobacterial isolates from the Randwick Chest Hospital, Sydney, in an 18-month period, 1970 to 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199110"} {"pmid": "4199111", "title": "Sodium cromoglycate in the treatment of chronic allergic rhinitis.", "content": "Sodium cromoglycate in the treatment of chronic allergic rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199111"} {"pmid": "4199112", "title": "The management of the sick diabetic--the physician's role in the prevention of diabetic coma.", "content": "The management of the sick diabetic--the physician's role in the prevention of diabetic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199112"} {"pmid": "4199115", "title": "Clinical utilization of plasmapheresis and cyclophosphamide in the treatment of malignant lymphoproliferative processes.", "content": "Clinical utilization of plasmapheresis and cyclophosphamide in the treatment of malignant lymphoproliferative processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199115"} {"pmid": "4199116", "title": "The influence of various dietary ascorbic acid levels on serum ascorbic acid and serum cholesterol values of the baboon (Papio ursinus) during captivity.", "content": "The influence of various dietary ascorbic acid levels on serum ascorbic acid and serum cholesterol values of the baboon (Papio ursinus) during captivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199116"} {"pmid": "4199117", "title": "Effect of ethylenebis (dithiocarbamic acid)disodium salt(nabam)and ethylenebis(dithiocarbamato)manganese(maneb) on Xenopus laevis development.", "content": "Effect of ethylenebis (dithiocarbamic acid)disodium salt(nabam)and ethylenebis(dithiocarbamato)manganese(maneb) on Xenopus laevis development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199117"} {"pmid": "4199118", "title": "Appendicular skeletal and visceral malformations induced by thalidomide in bonnet monkeys.", "content": "Appendicular skeletal and visceral malformations induced by thalidomide in bonnet monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199118"} {"pmid": "4199119", "title": "Teratogenic effects of 5-bromodexyuridine on the external morphology of Drosophila melanogaster.", "content": "Teratogenic effects of 5-bromodexyuridine on the external morphology of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199119"} {"pmid": "4199121", "title": "Immunological studies on Naja nigricollis antivenin.", "content": "Immunological studies on Naja nigricollis antivenin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199121"} {"pmid": "4199120", "title": "Immunological studies on Egyptian cobra antivenin.", "content": "Immunological studies on Egyptian cobra antivenin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199120"} {"pmid": "4199122", "title": "Iodination of cobrotoxin.", "content": "Iodination of cobrotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199122"} {"pmid": "4199123", "title": "Changes in antigenic character of fresh Australian snake venom upon aging.", "content": "Changes in antigenic character of fresh Australian snake venom upon aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199123"} {"pmid": "4199124", "title": "Purification of Aphanizomenon flos-aquae toxin and its chemical and physiological properties.", "content": "Purification of Aphanizomenon flos-aquae toxin and its chemical and physiological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199124"} {"pmid": "4199125", "title": "Immunological studies of scorpion (Buthus minax, L. Koch) venom.", "content": "Immunological studies of scorpion (Buthus minax, L. Koch) venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199125"} {"pmid": "4199126", "title": "Von Willebrand's syndrome presenting as an acquired bleeding disorder in association with a monoclonal gammopathy.", "content": "Von Willebrand's syndrome presenting as an acquired bleeding disorder in association with a monoclonal gammopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199126"} {"pmid": "4199127", "title": "Chronic hemolytic anemia due to cold agglutinins: a 20-year history of benign gammopathy with response to chlorambucil.", "content": "Chronic hemolytic anemia due to cold agglutinins: a 20-year history of benign gammopathy with response to chlorambucil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199127"} {"pmid": "4199128", "title": "Menstrual cycle characteristics and side of ovulation in the Rhesus monkey.", "content": "Menstrual cycle characteristics and side of ovulation in the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199128"} {"pmid": "4199129", "title": "A comparative study of the mechanisms of passive cutaneous anaphylaxis induced by mouse IgG, rabbit IgG, and rabbit F (ab')2 antibodies. I. The role of serotonin and histamine.", "content": "A comparative study of the mechanisms of passive cutaneous anaphylaxis induced by mouse IgG, rabbit IgG, and rabbit F (ab')2 antibodies. I. The role of serotonin and histamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199129"} {"pmid": "4199130", "title": "The cardiac auto-immune system. IX. Auto-immune myocarditis in rabbits immunized with rabbit heart.", "content": "The cardiac auto-immune system. IX. Auto-immune myocarditis in rabbits immunized with rabbit heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199130"} {"pmid": "4199131", "title": "The canine respiratory immune response.", "content": "The canine respiratory immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199131"} {"pmid": "4199132", "title": "Suppression of anaphylactic responses in mice by antilymphocyte sera, normal sera, and egg albumin.", "content": "Suppression of anaphylactic responses in mice by antilymphocyte sera, normal sera, and egg albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199132"} {"pmid": "4199133", "title": "Reduction by serum proteinase inhibitors of B. subtilis proteinase-induced hypersensitivity reactions.", "content": "Reduction by serum proteinase inhibitors of B. subtilis proteinase-induced hypersensitivity reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199133"} {"pmid": "4199134", "title": "Human leukocyte migration inhibition as an indicator of cellular hypersensitivity to soluble antigens.", "content": "Human leukocyte migration inhibition as an indicator of cellular hypersensitivity to soluble antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199134"} {"pmid": "4199135", "title": "Effects of phagocytosis by rabbit granulocytes on macromolecular synthesis and degradation in different species of bacteria.", "content": "Effects of phagocytosis by rabbit granulocytes on macromolecular synthesis and degradation in different species of bacteria. Phagocytosis and killing of gram-positive Bacillus megaterium and Micrococcus lysodeikticus by granulocytes in vitro is associated with almost immediate cessation of bacterial protein synthesis. By contrast, protein synthesis by Escherichia coli continues after ingestion and killing. After preincubation of E. coli with intact granulocytes for 15 min, when 95% or more of the bacteria can no longer multiply, induction of beta-galactosidase proceeds at rates about half of control values. With disrupted granulocytes, which kill E. coli as rapidly as intact cells, the rate of induction of beta-galactosidase does not fall until after 30 min of preincubation. We attribute the different effects of phagocytosis on the biochemical apparatus of these microorganisms to the different fates of their envelopes. Specifically labeled protein, ribonucleic acid, deoxyribonucleic acid, and lipid of all three species of bacteria and peptidoglycan of E. coli are apparently incompletely degraded during phagocytosis. However, the cell walls of M. lysodeikticus and B. megaterium undergo rapid and almost complete degradation. The resulting structural disintegration of these gram-positive microorganisms must cause extensive biochemical disorganization as well. Our evidence indicates that the E. coli envelope, on the other hand, retains sufficient structural organization to preserve integrated biochemical function for at least 1 h after the bacteria have lost the ability to multiply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199135"} {"pmid": "4199136", "title": "Guanosine diphosphate-L-fucose glycopeptide fucosyltransferase activity in Corynebacterium insidiosum.", "content": "Guanosine diphosphate-L-fucose glycopeptide fucosyltransferase activity in Corynebacterium insidiosum. The biosynthesis of a phytotoxic glycopeptide of Corynebacterium insidiosum involves guanosine diphosphate-l-fucosyltransferase activity. This enzyme activity is most consistently associated with the cellular membranes fraction. The optimal pH for the transfer reaction is 7.5. The partially hydrolyzed toxin serves as an acceptor (primer) of l-fucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199136"} {"pmid": "4199137", "title": "Specificity of the tyrosine-phenylalanine transport system in Bacillus subtilis.", "content": "Specificity of the tyrosine-phenylalanine transport system in Bacillus subtilis. l-Tyrosine and l-phenylalanine enter cells of Bacillus subtilis via a system of active transport that exhibits complex kinetic behavior. The specificity of the transport system was characterized both at low concentrations of transport substrate (where affinity for l-tyrosine or l-phenylalanine is high but capacity is low) and at high concentrations (where affinity is low but capacity is high). Specificity was not found to differ significantly as a function of either l-tyrosine or l-phenylalanine concentration. Kinetic analysis showed that the relationship between the uptake of l-phenylalanine and l-tyrosine is strictly competitive. Neither l-tyrosine nor l-phenylalanine uptake was competitively inhibited by other naturally occurring l-amino acids, indicating the importance of the phenyl side chain to uptake specificity. Hence, it is concluded that l-tyrosine and l-phenylalanine are transported by a common system that is specific for these two amino acids. The abilities of analogue derivatives of l-tyrosine and l-phenylalanine to inhibit the uptake of l-[(14)C]tyrosine and l-[(14)C]phenylalanine competitively were determined throughout a wide range of substrate and inhibitor concentrations. In this manner, the contributions of the side chain, the alpha-amino group and the carboxyl group to uptake specificity were established. It is concluded that the positively charged alpha-amino group contributes more significantly to uptake specificity than does the negatively charged carboxyl group. The recognition of a phenyl ring is an essential feature of specificity; other amino acids with aromatic side chains, such as the indole and imidazole rings of l-tryptophan and l-histidine, do not compete with l-tyrosine and l-phenylalanine for uptake. The presence of the p-hydroxy substitutent in the side chain (as in l-tyrosine) enhances the uptake of the aryl amino acid analogues investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199137"} {"pmid": "4199138", "title": "Ultrastructural studies of sporulation in a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis.", "content": "Ultrastructural studies of sporulation in a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis. Morphological studies of a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis have revealed that sporulation is inhibited at stage II when the cells are grown at 47.5 C. Growth and sporulation occur normally at 30 C with the mutant. The mutant grows normally at 47.5 C but is prevented from sporulating at the nonpermissive temperature by an abnormal septation during forespore membrane formation which prevents the subsequent engulfment process (stage III). The mutation affects the normal functioning of ribonucleic acid polymerase at the nonpermissive temperature resulting in abortive sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199138"} {"pmid": "4199139", "title": "Soluble antigens associated with infection with apple chlorotic leaf spot virus.", "content": "Soluble antigens associated with infection with apple chlorotic leaf spot virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199139"} {"pmid": "4199141", "title": "Dose distribution for cobalt 60 tangential irradiation of the breast and chest wall.", "content": "Dose distribution for cobalt 60 tangential irradiation of the breast and chest wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199141"} {"pmid": "4199142", "title": "Treatment of pain in chronic pancreatitis by irradiation.", "content": "Treatment of pain in chronic pancreatitis by irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199142"} {"pmid": "4199143", "title": "Cromolyn sodium in the management of the child with asthma: a symposium. Preliminary data from a collaborative group study.", "content": "Cromolyn sodium in the management of the child with asthma: a symposium. Preliminary data from a collaborative group study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199143"} {"pmid": "4199145", "title": "Reflections and thoughts on the use of cromolyn sodium in the asthmatic child.", "content": "Reflections and thoughts on the use of cromolyn sodium in the asthmatic child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199145"} {"pmid": "4199144", "title": "Experiences with cromolyn sodium in asthma in children.", "content": "Experiences with cromolyn sodium in asthma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199144"} {"pmid": "4199146", "title": "Personal observations on cromolyn sodium prophylaxis.", "content": "Personal observations on cromolyn sodium prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199146"} {"pmid": "4199147", "title": "Review and assessment of the efficacy of cromolyn sodium, particularly after long-term administration.", "content": "Review and assessment of the efficacy of cromolyn sodium, particularly after long-term administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199147"} {"pmid": "4199148", "title": "Pros and cons of cromolyn sodium prophylaxis. A summary of experiences with 70 asthmatic children.", "content": "Pros and cons of cromolyn sodium prophylaxis. A summary of experiences with 70 asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199148"} {"pmid": "4199149", "title": "The new field of plastics toxicology--methods and results.", "content": "The new field of plastics toxicology--methods and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199149"} {"pmid": "4199150", "title": "When a drug is the culprit.", "content": "When a drug is the culprit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199150"} {"pmid": "4199152", "title": "Production of macrophage migration inhibition factors by virus-infected cell cultures.", "content": "Production of macrophage migration inhibition factors by virus-infected cell cultures. Macrophage migration inhibitory (MIF-like) activity was demonstrated in the supernatant fluids from cultures of African green monkey kidney cells (BGM) infected with mumps virus or Newcastle disease virus. We could detect no such activity in noninfected cultures. The virus-induced activity reported here is not due to nonspecific cytotoxic material released by dead or dying cells, and it does not require cell replication for its production. Preliminary estimates of molecular weight by Sephadex G-100 chromatography revealed a broad band of activity associated with the 45,000 and 65,000 markers. These are significantly smaller than previously reported chemotactic substances from virus-infected cultures, and thus appear to represent different cell products. These MIF-like factors may be produced concomitantly with interferon. However, ultraviolet irradiation of appropriate duration abolishes the ability of viruses to induce substances with MIF-like activity while preserving the ability to induce interferon. This strongly suggests that interferon is not the agent responsible for the macrophage migration inhibition effect. The functional properties of these various cell products induced by virus infection suggest that they all may play a role in the response to virus infection in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199152"} {"pmid": "4199153", "title": "Immune response to Mycobacterium tuberculosis in rats.", "content": "Immune response to Mycobacterium tuberculosis in rats. After intravenous injection into rats, both the attenuated strain R1Rv and the virulent strain H37Rv of Mycobacterium tuberculosis grow in the liver and spleen. However, the infected rats mount a specific immune response with great rapidity, giving a false impression of natural resistance to the tubercle bacillus. Adoptive immunity to tuberculosis was achieved by transferring thoracic duct cells from immunized donors to normal syngeneic recipients. The transferred immunity was vested in a population of lymphocytes uncontaminated with macrophages. The adoptive immunity was effectively expressed against both attenuated and virulent tubercle bacilli, and it was shown to be immunologically specific. Lymphocytes which conferred immunity to tuberculosis were not protective against Listeria monocytogenes infection, and vice versa. Immunity could not be transferred with either normal thoracic duct lymphocytes (TDL), heat-killed sensitized TDL, or serum from specifically immunized donors. The ability of TDL from BCG-immunized donors to confer immunity was maintained at an unimpaired level for at least 3 months after immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199153"} {"pmid": "4199154", "title": "Extraction, purification, and chemical and immunological properties of the Streptococcus mutans group \"a\" polysaccharide cell wall antigen.", "content": "Extraction, purification, and chemical and immunological properties of the Streptococcus mutans group \"a\" polysaccharide cell wall antigen. An antigen of Streptococcus mutans has been extracted from HS6 (group \"a\") whole cells and repeatedly fractionated by Sephadex chromatography. The antigen is shown to be a polysaccharide and contains the S. mutans group \"a\" antigenic site and also a second antigenic site which is common to \"a\" strains and 2 of 3 group \"d\" strains. Immunological electrophoretic and chromatographic data indicate that the two sites exist in a single molecule. The polysaccharide has a molecular weight of 107,000 and is composed of glucose, galactose, glucosamine, and galactosamine. No significant quantities of lipid, phosphorus, glycerol, or ribitol are present. Immunological specificity of the group \"a\" polysaccharide site depends primarily on a d-glucose . d-glucose sequence, the \"a-d\" site on a terminal d-galactose. Water at 100 C and pepsin (pH 2.5) at room temperature are very effective in extracting the polysaccharide from lyophilized S. mutans cells. Trypsin and lysozyme are less effective. The antigen-antibody combining site appears to be located at the cell wall surface. A small quantity of enzyme-resistant protein (5%) is firmly linked to the antigen and is considered to be a remnant of a protein to which the polysaccharide is attached in the cell wall. The composition of the protein does not identify it as a part of the peptidoglycan. No reaction to the purified polysaccharide is obtained with antisera specific for teichoic acid glycerophosphate polymers from streptococci, staphylococci, or lactobacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199154"} {"pmid": "4199155", "title": "Acute cavitary histoplasmosis in Rhesus monkeys: influence of immunological status.", "content": "Acute cavitary histoplasmosis in Rhesus monkeys: influence of immunological status. Male rhesus monkeys were randomized into groups according to body weight, immunized with different Histoplasma capsulatum antigens, and two weeks later were infected intratracheally with 10(8)H. capsulatum yeast cells. Complement fixation antibody titers, skin tests, and chest X rays were performed at weekly intervals from immunization until autopsy, at which time the spleens were cultured and the lungs and other organs were dissected. Pulmonary cavities were found in 33% of the animals, and extrapulmonary dissemination was present in 85% of the animals. Delayed hypersensitivity and circulating antibody activity was detected in all animals at some time during the experimental period; however, animals which developed pulmonary cavities had a longer period before circulating antibodies were detected than animals which did not develop pulmonary cavities. Delayed hypersensitivity developed at approximately the same time in both cavitary and noncavitary animals. Early appearance of delayed hypersensitivity was associated with reduced amounts of extrapulmonary dissemination, in that animals with a later onset of skin test reactivity had more H. capsulatum cultured from the spleen. There was no correlation between the onset or titers of circulating antibodies and the spleen culture results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199155"} {"pmid": "4199156", "title": "Immunofluorescent study of the replication of infectious pancreatic necrosis virus in trout and Atlantic salmon cell cultures.", "content": "Immunofluorescent study of the replication of infectious pancreatic necrosis virus in trout and Atlantic salmon cell cultures. Cell cultures of trout gonad tissue (RTG-2) and Atlantic salmon heart, kidney, liver, and spleen tissue were inoculated with 50 50% tissue culture infective doses (TCID(50)) of infectious pancreatic necrosis (IPN) virus per cell, and the titer of cell-associated and released virus was determined from 2 to 16 h postinoculation (PI). Cover slips were collected over the same period and stained for IPN viral antigen by the direct immunofluorescent (FA) technique. Viral replication was detected after a latent period of approximately 2 to 4 h and reached a peak titer of 10(8.2) to 10(8.4) TCID(50) per ml at 8 to 10 h PI. The release of virus was more rapid in Atlantic salmon cells than in RTG-2 cells. Viral antigen was first detected by FA from 3 to 4 h PI. Approximately 75 to 80% of the cells contained antigen in the cytoplasm 9 to 11 h PI. The direct FA technique was found to be a sensitive method for detecting IPN virus in infected cells. Three strains of IPN virus were tested for serological cross reactions by FA and virus neutralization tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199156"} {"pmid": "4199151", "title": "Serologic characterization of a Malacosoma disstria Hübner (Lepidoptera: Lasiocampidae) cell line.", "content": "Serologic characterization of a Malacosoma disstria Hübner (Lepidoptera: Lasiocampidae) cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199151"} {"pmid": "4199157", "title": "Pathogenesis of aleutian disease of mink: nature of the antiglobulin reaction and elution of antibody from erythrocytes and glomeruli of infected mink.", "content": "Pathogenesis of aleutian disease of mink: nature of the antiglobulin reaction and elution of antibody from erythrocytes and glomeruli of infected mink. Erythrocytes from mink chronically infected with Aleutian disease virus (ADV) gave positive antiglobulin reactions with rabbit anti-mink immunoglobulin (Ig)G, anti-mink C3, and anti-mink serum, but did not react with anti-mink IgM. The strongest reaction was observed with anti-mink C3. Immunoelectrophoresis demonstrated that serum from rabbits injected with erythrocytes from ADV-infected mink gave a precipitin line with normal mink serum in the beta globulin region corresponding to C3. When normal mink erythrocytes were exposed to serum from ADV-infected mink, they were not sensitized, demonstrating that the antibodies in these mink sera were not directed against erythrocyte antigens. Glycine-hydrochloride buffer treatment of erythrocyte stromata and isolated glomeruli from ADV-infected mink yielded eluates containing serum proteins in the gamma globulin region which appeared to be IgG, and in the beta and alpha globulin regions which are probably complement components. In both erythrocyte and glomerular eluates, anti-ADV antibody was demonstrated. These findings suggested that the positive direct antiglobulin test and glomerulonephritis in Aleutian disease is due to the persistence of ADV and formation and deposition of ADV antigen-antibody-complement complexes on the erythrocyte surfaces and in glomerular capillaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199157"} {"pmid": "4199159", "title": "An orthopantomographic study of prevalence of impacted teeth.", "content": "An orthopantomographic study of prevalence of impacted teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199159"} {"pmid": "4199158", "title": "Hypogammaglobulinemia and thymic hypoplasia in horses: a primary combined immunodeficiency disorder.", "content": "Hypogammaglobulinemia and thymic hypoplasia in horses: a primary combined immunodeficiency disorder. A severe combined immunodeficiency disorder was demonstrated in two Arabian foals which were full siblings. The defect in the B-lymphocyte system was shown by hypogammaglobulinemia, lymphopenia, and absence of germinal centers. The almost total absence of thymic tissue in one foal and the lack of thymic dependent lymphocytes in the spleens of both foals demonstrate a T-lymphocyte defect. In a retrospective study of total available Arabian foal cases, 4 of 15 had evidence of immunodeficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199158"} {"pmid": "4199160", "title": "Cellular fibrinolytic activity of human alveolar bone.", "content": "Cellular fibrinolytic activity of human alveolar bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199160"} {"pmid": "4199161", "title": "Allogenic demineralized dentin implants in jaw defects of Java monkeys.", "content": "Allogenic demineralized dentin implants in jaw defects of Java monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199161"} {"pmid": "4199162", "title": "A histologic study of experimentally induced radicular cysts.", "content": "A histologic study of experimentally induced radicular cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199162"} {"pmid": "4199163", "title": "Modes of healing histologically after endodontic surgery in 70 cases.", "content": "Modes of healing histologically after endodontic surgery in 70 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199163"} {"pmid": "4199164", "title": "Correlation between histology and radiography in the assessment of healing after endodontic surgery.", "content": "Correlation between histology and radiography in the assessment of healing after endodontic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199164"} {"pmid": "4199165", "title": "Maxillary sinus and surgical movement of maxilla.", "content": "Maxillary sinus and surgical movement of maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199165"} {"pmid": "4199166", "title": "Age- and sex-dependence of the risk of intruding a root into the maxillary sinus.", "content": "Age- and sex-dependence of the risk of intruding a root into the maxillary sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199166"} {"pmid": "4199167", "title": "Antifibrinolytic effect of Apernyl in \"dry socket\".", "content": "Antifibrinolytic effect of Apernyl in \"dry socket\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199167"} {"pmid": "4199168", "title": "Radiographic criteria for the assessment of healing after endodontic surgery.", "content": "Radiographic criteria for the assessment of healing after endodontic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199168"} {"pmid": "4199169", "title": "A follow-up study of 1,000 cases treated by endodontic surgery.", "content": "A follow-up study of 1,000 cases treated by endodontic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199169"} {"pmid": "4199170", "title": "Cherubism.", "content": "Cherubism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199170"} {"pmid": "4199171", "title": "A histologic study of experimental oro-paranasal communications in monkeys.", "content": "A histologic study of experimental oro-paranasal communications in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199171"} {"pmid": "4199172", "title": "A multivariate analysis of the influence of various factors upon healing after endodontic surgery.", "content": "A multivariate analysis of the influence of various factors upon healing after endodontic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199172"} {"pmid": "4199173", "title": "A histobacteriologic study of dental and periapical structures after endodontic surgery.", "content": "A histobacteriologic study of dental and periapical structures after endodontic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199173"} {"pmid": "4199174", "title": "Quantitative PCB standards for electron capture gas chromatography.", "content": "Quantitative PCB standards for electron capture gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199174"} {"pmid": "4199175", "title": "Cellular localization of carbonic anhydrase in avian tissues by labeled inhibitor autoradiography.", "content": "Cellular localization of carbonic anhydrase in avian tissues by labeled inhibitor autoradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199175"} {"pmid": "4199176", "title": "Maltose in total parenteral nutrition of rats.", "content": "Maltose in total parenteral nutrition of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199176"} {"pmid": "4199177", "title": "Protein deficiency: contrasting effects on DNA and RNA metabolism in rat liver.", "content": "Protein deficiency: contrasting effects on DNA and RNA metabolism in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199177"} {"pmid": "4199179", "title": "Primate pulp response to an ultraviolet light cured restorative material.", "content": "Primate pulp response to an ultraviolet light cured restorative material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199179"} {"pmid": "4199178", "title": "Effect of dietary protein and magnesium on selected ATP phosphotransferases and neuromuscular behavior in young rats.", "content": "Effect of dietary protein and magnesium on selected ATP phosphotransferases and neuromuscular behavior in young rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199178"} {"pmid": "4199180", "title": "An autopsy case of leiomyosarcoma of the maxilla.", "content": "An autopsy case of leiomyosarcoma of the maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199180"} {"pmid": "4199181", "title": "Peripheral giant cell granulomas: an ultrastructural study of three lesions.", "content": "Peripheral giant cell granulomas: an ultrastructural study of three lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199181"} {"pmid": "4199182", "title": "The pathogenesis of hydro-testis after ligation of the vas deferens: a study in several species.", "content": "The pathogenesis of hydro-testis after ligation of the vas deferens: a study in several species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199182"} {"pmid": "4199183", "title": "The alpha cell in diabetic ketoacidosis.", "content": "The alpha cell in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199183"} {"pmid": "4199184", "title": "Medical abortion in South Australia. A critical assessment of early complications.", "content": "Medical abortion in South Australia. A critical assessment of early complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199184"} {"pmid": "4199186", "title": "Neglect after cingulectomy.", "content": "Neglect after cingulectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199186"} {"pmid": "4199187", "title": "Cerebrospinal fluid levels of IgG, IgA and IgM in neurologic diseases.", "content": "Cerebrospinal fluid levels of IgG, IgA and IgM in neurologic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199187"} {"pmid": "4199189", "title": "The release of TSH from organ cultures of human fetal pituitary glands.", "content": "The release of TSH from organ cultures of human fetal pituitary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199189"} {"pmid": "4199191", "title": "16Alpha-hydroxylase activity in uterine tissue of the rhesus monkey.", "content": "16Alpha-hydroxylase activity in uterine tissue of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199191"} {"pmid": "4199192", "title": "The time course of recombination of HCG subunits observed by immunological methods and circular dichroism studies.", "content": "The time course of recombination of HCG subunits observed by immunological methods and circular dichroism studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199192"} {"pmid": "4199190", "title": "The effect of calcitonin on glucose assimilation and insulin secretion in man.", "content": "The effect of calcitonin on glucose assimilation and insulin secretion in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199190"} {"pmid": "4199193", "title": "Subcellular distribution of glucuronyltransferase and its relevance for the enterohepatic circulation of oestrogens.", "content": "Subcellular distribution of glucuronyltransferase and its relevance for the enterohepatic circulation of oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199193"} {"pmid": "4199194", "title": "Phonophoresis as a new method for perfusion of the ovary in vivo.", "content": "Phonophoresis as a new method for perfusion of the ovary in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199194"} {"pmid": "4199195", "title": "Aromatization of 3H-pregnenolone sulfate in the rhesus monkey liver in vivo.", "content": "Aromatization of 3H-pregnenolone sulfate in the rhesus monkey liver in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199195"} {"pmid": "4199196", "title": "The application of synthetic LRF and TRF in a combined function test in patients with pituitary tumors.", "content": "The application of synthetic LRF and TRF in a combined function test in patients with pituitary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199196"} {"pmid": "4199198", "title": "Perforation in acquired diverticular disease of the terminal ileum.", "content": "Perforation in acquired diverticular disease of the terminal ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199198"} {"pmid": "4199203", "title": "Thymus dependency of cells involved in transfer of delayed hypersensitivity to Listeria monocytogenes in mice.", "content": "Thymus dependency of cells involved in transfer of delayed hypersensitivity to Listeria monocytogenes in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199203"} {"pmid": "4199205", "title": "A review of the development of the health services of Rhodesia from 1923 to the present day.", "content": "A review of the development of the health services of Rhodesia from 1923 to the present day.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199205"} {"pmid": "4199204", "title": "Reversal by the MER tubercle bacillus fraction of the suppressive effects of heterologous antilymphocytic serum (ALS) on the allograft reactivity of mice.", "content": "Reversal by the MER tubercle bacillus fraction of the suppressive effects of heterologous antilymphocytic serum (ALS) on the allograft reactivity of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199204"} {"pmid": "4199197", "title": "Mitochondria and chloroplasts revisited.", "content": "Mitochondria and chloroplasts revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199197"} {"pmid": "4199209", "title": "Limbic projections to the thalamus.", "content": "Limbic projections to the thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199209"} {"pmid": "4199211", "title": "Genotype and phenotype in human chromosome aberrations and in the minute mutants of Drosophila melanogaster.", "content": "Genotype and phenotype in human chromosome aberrations and in the minute mutants of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199211"} {"pmid": "4199215", "title": "Syntheses and biological activities of 7-ethyl-8-chloro-10-(1'-D-ribityl) isoalloxazine and 7-chloro-8-ethyl-10(1'-D-ribityl) isoalloxazine, analogs of riboflavin.", "content": "Syntheses and biological activities of 7-ethyl-8-chloro-10-(1'-D-ribityl) isoalloxazine and 7-chloro-8-ethyl-10(1'-D-ribityl) isoalloxazine, analogs of riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199215"} {"pmid": "4199216", "title": "Antiasthma agents. 1. 4-Oxo-4H-(1) benzothieno-(3,2-b)pyran-2-carboxylic acid and 4-oxo-4H-(1)benzofuro(3,2-b)pyran-2-carboxylic acid.", "content": "Antiasthma agents. 1. 4-Oxo-4H-(1) benzothieno-(3,2-b)pyran-2-carboxylic acid and 4-oxo-4H-(1)benzofuro(3,2-b)pyran-2-carboxylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199216"} {"pmid": "4199217", "title": "Antiparasitic nitroimidazoles. 7. Some 4- and 5-styrylnitroimidazoles.", "content": "Antiparasitic nitroimidazoles. 7. Some 4- and 5-styrylnitroimidazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199217"} {"pmid": "4199218", "title": "Ouabain-dependent potassium-potassium exchange in the toad bladder.", "content": "Ouabain-dependent potassium-potassium exchange in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199218"} {"pmid": "4199220", "title": "Transformation in Bacillus subtilis. Fate of newly introduced transforming DNA.", "content": "Transformation in Bacillus subtilis. Fate of newly introduced transforming DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199220"} {"pmid": "4199223", "title": "Nursing care study: twins in Papua.", "content": "Nursing care study: twins in Papua.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199223"} {"pmid": "4199225", "title": "Phototaxis and sensory transduction in Euglena.", "content": "Phototaxis and sensory transduction in Euglena. The accumulation of Euglena gracilis in an illuminated region is brought about by two main mechanisms: orientation and subsequent directed movement (positive phototaxis) toward light scattered from particles in the illuminated zone; and by the trapping of cells in this region because of shock reactions experienced upon the cells encountering a sudden decrease of light intensity at the light-dark boundary (inverse photophobic responses). Phototactic orientation is mediated by inverse photophobic reactions which occur when the shadow of the stigma periodically falls upon the photoreceptor proper. Euglena also exhibits shock reactions when an already high light intensity is increased further (direct photophobic responses). The expression of both types of phobic responses depends upon stimulus intensity and adaptation of the sensory system in a seemingly complex way. A definition of the minimum components of the stimulus transduction system and a systems analytical approach to the study of input-output relationships enables one to construct an electronic analog of the cell's signal processing system that converts the photoreceptor input to commands which activate or inhibit flagellar reorientation. Computer simulation studies show that this model has considerable predictive value. It is hoped that with the approach presented in this article, a generalized model has become available for dealing with the questions of sensory transduction in aneural systems. Certainly, at this point more questions have been raised than have been answered. Where is the processing device located? Are its kinetic properties determined by electrical processes or by the rates of chemical reactions? Is the processor, and thereby the behavior of the orgamism, modulated by natural environmental parameters, and can it be modified permanently through more drastic chemical treatment of the cell? Is the system capable of permanent or transitory modification through repeated response, that is, does it exhibit phenomena analogous to learning and memory in higher organisms? These are only a few of the problems that require study in the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199225"} {"pmid": "4199226", "title": "Phenocopies of pigmentary and behavioral effects of the yellow mutant in Drosophila induced by alpha-dimethyltyrosine.", "content": "Phenocopies of pigmentary and behavioral effects of the yellow mutant in Drosophila induced by alpha-dimethyltyrosine. alpha-Dimethyltyrosine induces a phenocopy of the body color mutant yellow when fed to larvae of Drosophila melanogaster. The compound also induces changes in male courtship behavior which are similar to the effects of the mutant gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199226"} {"pmid": "4199227", "title": "Effects of aminoglutethimide (Elipten Ciba), a steroid biosynthesis blocking agent, on adrenal glands in Cushing's syndrome.", "content": "Effects of aminoglutethimide (Elipten Ciba), a steroid biosynthesis blocking agent, on adrenal glands in Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199227"} {"pmid": "4199228", "title": "Osteocytes in chronic uremia. Differential count of osteocytes in human femoral bone.", "content": "Osteocytes in chronic uremia. Differential count of osteocytes in human femoral bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199228"} {"pmid": "4199213", "title": "Pharmacology of cefazolin in human volunteers.", "content": "Pharmacology of cefazolin in human volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199213"} {"pmid": "4199214", "title": "Liver enzyme induction by anticonvulsant drugs, and its relationship to disturbed calcium and folic acid metabolism.", "content": "Liver enzyme induction by anticonvulsant drugs, and its relationship to disturbed calcium and folic acid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199214"} {"pmid": "4199229", "title": "Infantile neurological Gaucher's disease in three siblings. An ultrastructural study.", "content": "Infantile neurological Gaucher's disease in three siblings. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199229"} {"pmid": "4199221", "title": "Morphological abnormalities of fungi induced by volatile microbial metabolites.", "content": "Morphological abnormalities of fungi induced by volatile microbial metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199221"} {"pmid": "4199234", "title": "Ultrastructural changes in the superficial layers of the superior colliculus in Galago crassicaudatus (primates) after eye enucleation.", "content": "Ultrastructural changes in the superficial layers of the superior colliculus in Galago crassicaudatus (primates) after eye enucleation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199234"} {"pmid": "4199237", "title": "Impaired delayed hypersensitivity in juvenile rheumatoid arthritis.", "content": "Impaired delayed hypersensitivity in juvenile rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199237"} {"pmid": "4199238", "title": "Factors influencing biometric potency assays of brucella allergens in guinea-pigs.", "content": "Factors influencing biometric potency assays of brucella allergens in guinea-pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199238"} {"pmid": "4199239", "title": "The role of polymorphonuclear leucocytes in protecting mice vaccinated against Pseudomon as aeruginosa infections.", "content": "The role of polymorphonuclear leucocytes in protecting mice vaccinated against Pseudomon as aeruginosa infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199239"} {"pmid": "4199240", "title": "Morquio-Brailsford disease. A report of four affected sisters with absence of excessive keratan sulphate in the urine.", "content": "Morquio-Brailsford disease. A report of four affected sisters with absence of excessive keratan sulphate in the urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199240"} {"pmid": "4199241", "title": "Spondylometaphyseal dysplasia.", "content": "Spondylometaphyseal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199241"} {"pmid": "4199242", "title": "Treatment of ano-rectal gonorrhoea with ampicillin.", "content": "Treatment of ano-rectal gonorrhoea with ampicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199242"} {"pmid": "4199244", "title": "Analgesics and asthma.", "content": "Analgesics and asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199244"} {"pmid": "4199243", "title": "T-strain mycoplasma isolation and serology in women.", "content": "T-strain mycoplasma isolation and serology in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199243"} {"pmid": "4199245", "title": "Thyrotrophin-releasing hormone in use.", "content": "Thyrotrophin-releasing hormone in use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199245"} {"pmid": "4199246", "title": "Long-term domiciliary oxygen in chronic bronchitis with pulmonary hypertension.", "content": "Long-term domiciliary oxygen in chronic bronchitis with pulmonary hypertension. Five patients with chronic bronchitis and pulmonary hypertension were treated with oxygen in their homes for periods of between 6 and 24 months. Oxygen was supplied for 15 hours daily from cylinders or from an oxygen concentrator and few practical difficulties arose. After 23 to 59 weeks of treatment there were significant decreases in pulmonary arterial pressure and vascular resistance, and four of the five patients no longer had pulmonary hypertension at rest. Two of these patients had shown little response after three weeks of treatment. There was a reduction in the number of episodes of congestive cardiac failure compared with the corresponding period before treatment. Two of the patients improved enough to return to work. These results are encouraging enough to justify a controlled trial of the treatment in a large number of patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199246"} {"pmid": "4199247", "title": "Topical disodium cromoglycate.", "content": "Topical disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199247"} {"pmid": "4199249", "title": "Mortality in protein calorie malnutrition.", "content": "Mortality in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199249"} {"pmid": "4199250", "title": "Endotracheal gentamicin for the prevention of bronchial infections in patients with tracheotomy.", "content": "Endotracheal gentamicin for the prevention of bronchial infections in patients with tracheotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199250"} {"pmid": "4199253", "title": "Electron microscopy of Sarcocystis sp.: cyst wall, micropore, rhoptries, and an unidentified body.", "content": "Electron microscopy of Sarcocystis sp.: cyst wall, micropore, rhoptries, and an unidentified body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199253"} {"pmid": "4199254", "title": "Enzyme levels in cercariae and adult Schistosoma mansoni.", "content": "Enzyme levels in cercariae and adult Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199254"} {"pmid": "4199255", "title": "The stability and fractionation of malarial antigens from the blood of Africans infected with Plasmodium falciparum.", "content": "The stability and fractionation of malarial antigens from the blood of Africans infected with Plasmodium falciparum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199255"} {"pmid": "4199256", "title": "The turnover of folate coenzymes in murine lymphoma cells.", "content": "The turnover of folate coenzymes in murine lymphoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199256"} {"pmid": "4199257", "title": "The proteolytic enzymes of the K-1 strain of Streptomyces griseus obtained from a commercial preparation (Pronase). Purification and characterization of the aminopeptidases.", "content": "The proteolytic enzymes of the K-1 strain of Streptomyces griseus obtained from a commercial preparation (Pronase). Purification and characterization of the aminopeptidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199257"} {"pmid": "4199258", "title": "Biological mechanisms involved in the formation of deoxy sugars. VII. Biosynthesis of 6-deoxy-L-talose.", "content": "Biological mechanisms involved in the formation of deoxy sugars. VII. Biosynthesis of 6-deoxy-L-talose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199258"} {"pmid": "4199259", "title": "The kinetics of dissociation of Cu2+-bovine serum albumin biuret complexes.", "content": "The kinetics of dissociation of Cu2+-bovine serum albumin biuret complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199259"} {"pmid": "4199260", "title": "Purification and properties of the sigma subunit of ribonucleic acid polymerase from vegetative Bacillus subtilis.", "content": "Purification and properties of the sigma subunit of ribonucleic acid polymerase from vegetative Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199260"} {"pmid": "4199261", "title": "Comparative size and properties of the sigma subunits of ribonucleic acid polymerase from Bacillus subtilis and Escherichia coli.", "content": "Comparative size and properties of the sigma subunits of ribonucleic acid polymerase from Bacillus subtilis and Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199261"} {"pmid": "4199262", "title": "Effects of thyrotropin-releasing hormone and hydrocortisone on synthesis and degradation of prolactin in a rat pituitary cell strain.", "content": "Effects of thyrotropin-releasing hormone and hydrocortisone on synthesis and degradation of prolactin in a rat pituitary cell strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199262"} {"pmid": "4199263", "title": "In vitro synthesis of ribosomal ribonucleic acid by a deoxyribonucleic acid-protein complex isolated from Escherichia coli.", "content": "In vitro synthesis of ribosomal ribonucleic acid by a deoxyribonucleic acid-protein complex isolated from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199263"} {"pmid": "4199264", "title": "A human left ventricular control system model for cardiac diagnosis.", "content": "A human left ventricular control system model for cardiac diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199264"} {"pmid": "4199265", "title": "Pattern variability in microtubular arrays associated with the tentacles of Actinobolina (Ciliatea: Gymnostomatida).", "content": "Pattern variability in microtubular arrays associated with the tentacles of Actinobolina (Ciliatea: Gymnostomatida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199265"} {"pmid": "4199266", "title": "Ultracytochemical observations of glycogen synthesis and storage during infradian growth of Tetrahymena pyriformis.", "content": "Ultracytochemical observations of glycogen synthesis and storage during infradian growth of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199266"} {"pmid": "4199267", "title": "Chemistry of releasing hormones.", "content": "Chemistry of releasing hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199267"} {"pmid": "4199268", "title": "Thyrotrophin releasing hormone and thyroid function.", "content": "Thyrotrophin releasing hormone and thyroid function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199268"} {"pmid": "4199269", "title": "Pathogenic lactobacilli.", "content": "Pathogenic lactobacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199269"} {"pmid": "4199270", "title": "Gonococcal enhancement of staphylococcal virulence for the mouse.", "content": "Gonococcal enhancement of staphylococcal virulence for the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199270"} {"pmid": "4199271", "title": "Synergism between beta-lactam antibiotics: a test of theoretical predictions made with Staphylococcus aureus.", "content": "Synergism between beta-lactam antibiotics: a test of theoretical predictions made with Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199271"} {"pmid": "4199272", "title": "Unstable resistance to methicillin in Staphylococcus epidermidis.", "content": "Unstable resistance to methicillin in Staphylococcus epidermidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199272"} {"pmid": "4199273", "title": "An immunodiffusion analysis of strains of Mycobacterium ulcerans isolated in Australia, Malaya, Mexico, Uganda and Zaire.", "content": "An immunodiffusion analysis of strains of Mycobacterium ulcerans isolated in Australia, Malaya, Mexico, Uganda and Zaire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199273"} {"pmid": "4199274", "title": "Pyocine typing of mucoid strains of Pseudomonas aeruginosa isolated from children with cystic fibrosis.", "content": "Pyocine typing of mucoid strains of Pseudomonas aeruginosa isolated from children with cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199274"} {"pmid": "4199275", "title": "Quantitative study of P substance in the megaesophagus and megacolon of human Trypanosoma cruzi infections.", "content": "Quantitative study of P substance in the megaesophagus and megacolon of human Trypanosoma cruzi infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199275"} {"pmid": "4199276", "title": "The isolation of micro-organisms from creams and ointments by membrane filtration.", "content": "The isolation of micro-organisms from creams and ointments by membrane filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199276"} {"pmid": "4199277", "title": "Observations of the mechanism of action of the sulfonylureas under clinical conditions.", "content": "Observations of the mechanism of action of the sulfonylureas under clinical conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199277"} {"pmid": "4199282", "title": "Premature births in California sea lions: association with high organochlorine pollutant residue levels.", "content": "Premature births in California sea lions: association with high organochlorine pollutant residue levels. Premature pupping in California sea lions has been noted on the breeding islands since 1968. Organochlorine pesticides and polychlorinated biphenyl residues were two to eight times higher in tissues of premature parturient females and pups than in similar tissues of full-term parturient females and pups collected on San Miguel Island in 1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199282"} {"pmid": "4199283", "title": "Cell-mediated immune responses in vitro: interaction of thymus-derived cells during cytotoxic allograft responses in vitro.", "content": "Cell-mediated immune responses in vitro: interaction of thymus-derived cells during cytotoxic allograft responses in vitro. A mouse in vitro allograft system was used to check for synergism among thymus-derived cells during cell-mediated immune responses. Synergistic interactions occurred between thymus and thymus-derived lymphocytes. The majority of precursors of cytotoxic effector cells were peripheral thymus-derived cells; thymocytes acted mainly as amplifier cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199283"} {"pmid": "4199285", "title": "Behavior of free-ranging macaques after intraventricular 6-hydroxydopamine.", "content": "Behavior of free-ranging macaques after intraventricular 6-hydroxydopamine. Macaques (Macaca mulatta) observed in a free-ranging colony on Guayacan Island, Puerto Rico, were significantly different in their social interactions, initiatives, facial expressions, and postures after intraventricular 6-hydroxydopamine compared with sham-treated and field controls. This study extends the known effects of 6-hydroxydopamine and catecholamine depletion to the social interactions of a higher primate species under free-ranging conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199285"} {"pmid": "4199284", "title": "Biosynthesis of a vasotocin-like peptide in cell cultures from pineal glands of human fetuses.", "content": "Biosynthesis of a vasotocin-like peptide in cell cultures from pineal glands of human fetuses. Cultured cells from pineal glands of human fetuses release into their media a substance that has antidiuretic and hydroosmotic activities. The ratio of these activities as well as their susceptibility to tryptic digestion, specific oxidative inactivation by tyrosinase, and reductive inactivation by sodium thioglycollate, indicates the presence of a basic peptide, presumably identical with arginine vasotocin. The total amount of this peptide released into the culture media during 38 days of incubation is about ten times greater than the amount contained in nonincubated pineal glands from fetuses of the same age, strongly suggesting that fetal ependymal cells from the pineal gland can synthesize in vitro a peptide similar to arginine vasotocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199284"} {"pmid": "4199286", "title": "Studies in actinomycetes in Egyptian soils. II. The occurrence of antibiotic-producing actinomycetes.", "content": "Studies in actinomycetes in Egyptian soils. II. The occurrence of antibiotic-producing actinomycetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199286"} {"pmid": "4199278", "title": "Black piedra among Brazilian Indians.", "content": "Black piedra among Brazilian Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199278"} {"pmid": "4199288", "title": "Antimicrobial principles in leaves of Lawsonia inermis L.", "content": "Antimicrobial principles in leaves of Lawsonia inermis L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199288"} {"pmid": "4199289", "title": "Production of candicidin by Streptomyces griseus.", "content": "Production of candicidin by Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199289"} {"pmid": "4199290", "title": "Arterial CO2, O2, pH, and HCO3- values of ectotherms living in the Amazon.", "content": "Arterial CO2, O2, pH, and HCO3- values of ectotherms living in the Amazon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199290"} {"pmid": "4199291", "title": "The distribution of manual asymmetry.", "content": "The distribution of manual asymmetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199291"} {"pmid": "4199281", "title": "Hemagglutination with preserved, sensitized cells, a practical test for routine serologic diagnosis of American trypanosomiasis.", "content": "Hemagglutination with preserved, sensitized cells, a practical test for routine serologic diagnosis of American trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199281"} {"pmid": "4199296", "title": "Discordant response to nitroglycerin of strain gauge arch and maximum rate of rise of left ventricular pressure in dogs.", "content": "Discordant response to nitroglycerin of strain gauge arch and maximum rate of rise of left ventricular pressure in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199296"} {"pmid": "4199317", "title": "Alcoholism as a predictive index of elapsed time between grand mal seizures.", "content": "Alcoholism as a predictive index of elapsed time between grand mal seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199317"} {"pmid": "4199318", "title": "Asymmetric bidirectional replication of Bacillus subtilis chromosome.", "content": "Asymmetric bidirectional replication of Bacillus subtilis chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199318"} {"pmid": "4199319", "title": "Topography of chromosome membrane junction in Bacillus subtilis.", "content": "Topography of chromosome membrane junction in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199319"} {"pmid": "4199320", "title": "Mapping genes for the ribosomal protein of Drosophila.", "content": "Mapping genes for the ribosomal protein of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199320"} {"pmid": "4199324", "title": "The hypocalcemic effect of protamine in goats and sheep.", "content": "The hypocalcemic effect of protamine in goats and sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199324"} {"pmid": "4199327", "title": "The effect of spironolactone on the mercury content of various organs of rats given methyl mercury.", "content": "The effect of spironolactone on the mercury content of various organs of rats given methyl mercury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199327"} {"pmid": "4199330", "title": "Changes in leucocyte distribution associated with age in thoroughbred horses.", "content": "Changes in leucocyte distribution associated with age in thoroughbred horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199330"} {"pmid": "4199332", "title": "Integration of mutagenicity studies into toxicity tests.", "content": "Integration of mutagenicity studies into toxicity tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199332"} {"pmid": "4199333", "title": "New formaldehyde base disinfectants.", "content": "New formaldehyde base disinfectants. Preparations of formaldehyde in various organic liquids-ethylene glycol, glycerol, and propylene glycol-serve as effective disinfectants towards microbial vegetative cells and spores. This disinfection is a temperature-dependent process and is manifest when these formaldehyde base disinfectants are dissolved in water. The irritating vapors associated with formaldehyde disinfection are not present in either of these new formaldehyde base disinfectants or in aqueous solutions of them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199333"} {"pmid": "4199334", "title": "Simplified method for producing pyocins from Pseudomonas aeruginosa.", "content": "Simplified method for producing pyocins from Pseudomonas aeruginosa. Good yields of pyocin are obtained when Pseudomonas aeruginosa is grown in Trypticase soy broth (without glucose) (BBL) plus 1% potassium nitrate. As a result, pyocin production for routine epidemiological typing can be done in screw-cap tubes, without mechanical agitation or mitomycin C induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199334"} {"pmid": "4199335", "title": "Volatile compounds produced in sterile fish muscle (Sebastes melanops) by Pseudomonas putrefaciens, Pseudomonas fluorescens, and an Achromobacter species.", "content": "Volatile compounds produced in sterile fish muscle (Sebastes melanops) by Pseudomonas putrefaciens, Pseudomonas fluorescens, and an Achromobacter species. Volatile compounds produced by Pseudomonas putrefaciens, P. fluorescens, and an Achromobacter species in sterile fish muscle (Sebastes melanops) were identified by combined gas-liquid chromatography and mass spectrometry. Compounds produced by P. putrefaciens included methyl mercaptan, dimethyl disulfide, dimethyl trisulfide, 3-methyl-1-butanol, and trimethylamine. With the exception of dimethyl trisulfide, the same compounds were produced by an Achromobacter species. Methyl mercaptan and dimethyl disulfide were the major sulfur-containing compounds produced by P. fluorescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199335"} {"pmid": "4199336", "title": "Preparation, sensitivity, and specificity of Limulus lysate for endotoxin assay.", "content": "Preparation, sensitivity, and specificity of Limulus lysate for endotoxin assay. Limulus amoebocyte lysate was prepared from a total of 180 crabs during 1971 and 1972 by using a slightly modified lysate preparation procedure. Marked variability of lysate potency was noted both years. In addition, lysate quality appeared diminished in 1972 as compared with 1971. Different lysate batches were evaluated for potency by using a variety of endotoxin preparations. Variations in batch potencies were observed, but little variation in reactivity among different endotoxin preparations was noted. Use of potent lysate batches allowed detection of endotoxin concentrations as low as 100 pg/ml. No endotoxinlike activity was observed from 11 different strains of yeast by use of the Limulus assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199336"} {"pmid": "4199337", "title": "Stimulation of lactic acid bacteria by a micrococcus isolate: evidence for multiple effects.", "content": "Stimulation of lactic acid bacteria by a micrococcus isolate: evidence for multiple effects. Growth of, and rate of acid production by, six cultures of lactic acid bacteria were increased in the presence of Micrococcus isolate F4 or a preparation of its capsular material. Concentrations of hydrogen peroxide found in pure cultures of the lactic acid bacteria were not detectable, or were greatly reduced, in mixed culture with Micrococcus isolate F4. The capsular material was not as effective as whole cells in preventing accumulation of H(2)O(2). Catalase stimulated growth of, and the rate of acid production by, the lactic acid bacteria, but not to the same extent as Micrococcus isolate F4 in some cultures. The existence of two mechanisms for micrococcal stimulation of the lactic acid bacteria is postulated. One mechanism involves removal of H(2)O(2); the other has not been characterized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199337"} {"pmid": "4199339", "title": "Biomagnification of p, p'-DDT and methoxychlor by bacteria.", "content": "Biomagnification of p, p'-DDT and methoxychlor by bacteria. Aerobacter aerogenes and Bacillus subtilis accumulated p, p'-DDT and methoxychlor directly from water. Uptake of both (14)C-labeled organochlorine insecticides was rapid; 80 to 90% of the 24-h residues were reached within 30 min. Total cellular residues varied linearly with concentrations of DDT and methoxychlor in water ranging from 0.5 to 5.0 mug/liter. The residue magnification factors from water were between 1,400- to 4,300-fold, but were independent of insecticide concentrations in water. When the insecticide-exposed microbial cells were washed with pesticide-free water, DDT residues were 45% in A. aerogenes and 30% in B. subtilis, whereas the methoxychlor level decreased nearly 75% in both organisms. Subsequent washing did not further reduce the insecticide residue. Autoclave-killed bacteria also rapidly adsorbed DDT and methoxychlor from water and, in some instances, residues were higher than in the living cells. Molecular polarity and lipid solubility appear to influence the retention of the organochlorine insecticides by bacterial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199339"} {"pmid": "4199338", "title": "Comparative evaluation of five serological methods for the diagnosis of sporotrichosis.", "content": "Comparative evaluation of five serological methods for the diagnosis of sporotrichosis. The diagnosis of sporotrichosis can be time consuming. Serological procedures could facilitate the rapid and accurate diagnosis of this disease. A slide latex agglutination (SLA) test for sporotrichosis was developed and compared with the tube agglutination (TA), complement fixation (CF), and immunodiffusion (ID) tests in the serological study of 80 proven human cases of sporotrichosis representing the cutaneous, subcutaneous, and extracutaneous forms of the disease. In addition, the indirect fluorescent antibody (IFA) technique was applied to 61 case sera. In the SLA test, latex particles sensitized with culture filtrate antigens from the yeast form of Sporothrix schenckii (B 959) detected 94% of the cases, as compared to 96% of the cases detected by the TA test, 68% by the CF test, and 56% by the ID test. The IFA test detected 90% of the 61 cases. The SLA and ID tests were specific, showing no reactions with sera from 86 persons with no disease or with diseases other than sporotrichosis. Because of its sensitivity, specificity, ease of performance, and ability to provide results in 5 min, the SLA test is highly recommended for routine use in the clinical laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199338"} {"pmid": "4199340", "title": "Characterization of mild thermal stress in Pseudomonas fluorescens and its repair.", "content": "Characterization of mild thermal stress in Pseudomonas fluorescens and its repair. The exposure of exponentially growing Pseudomonas fluorescens P7 cells to heating at 36 C for 2 h in a defined medium, followed by cooling to 25 C and further incubation at this, the optimal growth temperature, resulted in the apparent death of approximately 99% of the cells, as determined by their inability to form colonies on Trypticase soy agar. Continued incubation at 25 C resulted in an extremely rapid increase in the Trypticase soy agar count, demonstrating that the phenomenon observed was not death but rather injury. Presumptive evidence of heat-stimulated ribonucleic acid (RNA) degradation and membrane damage was provided by the observed loss of 260-nm absorbing materials. Confirmation of RNA degradation was obtained by colorimetric analysis. Ribosomal RNA from normal and injured cells, which was electrophoretically separated on polyacrylamide gels, revealed that the 23S and 16S species were only partially destroyed. Inhibitor studies demonstrated, however, that RNA synthesis was necessary for recovery. The unusual accumulation of 17S RNA during recovery pointed to the presence of a heat-induced lesion in the RNA maturation process. A thermally induced membrane lesion is also discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199340"} {"pmid": "4199341", "title": "Differential counting in mixed cultures with coulter counters.", "content": "Differential counting in mixed cultures with coulter counters. A critical comparison of Coulter, viable, and microscope counts for several mixed cultures of microorganisms has been made. This investigation shows that Coulter counting can provide reliable estimates of microbial numbers in mixed cultures. Precautions and limitations of Coulter counting in mixed cultures are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199341"} {"pmid": "4199342", "title": "Insulin degradation. V. Unmasking of glutathione-insulin transhydrogenase in rat liver microsomal membrane.", "content": "Insulin degradation. V. Unmasking of glutathione-insulin transhydrogenase in rat liver microsomal membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199342"} {"pmid": "4199343", "title": "Tritium incorporation and retention in photosynthesizing algae.", "content": "Tritium incorporation and retention in photosynthesizing algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199343"} {"pmid": "4199344", "title": "Physical-chemical properties of stable yeast ribosomes and ribosomal subunits.", "content": "Physical-chemical properties of stable yeast ribosomes and ribosomal subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199344"} {"pmid": "4199345", "title": "Transcription during cell differentiation in Naegleria gruberi. Preferential synthesis of messenger RNA.", "content": "Transcription during cell differentiation in Naegleria gruberi. Preferential synthesis of messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199345"} {"pmid": "4199346", "title": "Studies on bovine pancreatic deoxyribonuclease A. I. General properties and activation with different bivalent metals.", "content": "Studies on bovine pancreatic deoxyribonuclease A. I. General properties and activation with different bivalent metals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199346"} {"pmid": "4199347", "title": "Trace elements and skin pigmentation.", "content": "Trace elements and skin pigmentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199347"} {"pmid": "4199348", "title": "Quantitative haemagglutination. 4. Effect of neuraminidase treatment on agglutination by blood group antibodies.", "content": "Quantitative haemagglutination. 4. Effect of neuraminidase treatment on agglutination by blood group antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199348"} {"pmid": "4199350", "title": "Significance of Pseudomonas aeruginosa in sputum.", "content": "Significance of Pseudomonas aeruginosa in sputum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199350"} {"pmid": "4199349", "title": "Hyperamylasaemia in diabetic ketosis.", "content": "Hyperamylasaemia in diabetic ketosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199349"} {"pmid": "4199351", "title": "Pyogenic vertebral osteomyelitis in heroin addicts.", "content": "Pyogenic vertebral osteomyelitis in heroin addicts. The diagnosis of pyogenic vertebral osteomyelitis was made in seven narcotic addicts between 1967 and 1972. Vertebrae involved were either cervical or lumbar. Bacteriologic diagnosis was made in each case by percutaneous needle biopsy and aspiration. Staphylococcus aureus was cultured in two patients. Five patients had infections due to Gram-negative bacteria, including Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterobacter. All patients were cured by treatment with antibiotics and immobilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199351"} {"pmid": "4199353", "title": "Inactivation of cultured human cells and control of C3H mouse mammary tumors with accelerated nitrogen ions.", "content": "Inactivation of cultured human cells and control of C3H mouse mammary tumors with accelerated nitrogen ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199353"} {"pmid": "4199352", "title": "Radioprotection of tumor and normal tissues by thiophosphate compounds.", "content": "Radioprotection of tumor and normal tissues by thiophosphate compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199352"} {"pmid": "4199354", "title": "Growth retardation in children after megavoltage irradiation of the spine.", "content": "Growth retardation in children after megavoltage irradiation of the spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199354"} {"pmid": "4199355", "title": "Results of regional radiotherapy in localized Hodgkin's disease in children.", "content": "Results of regional radiotherapy in localized Hodgkin's disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199355"} {"pmid": "4199356", "title": "Radiation therapy in the treatment of childhood astrocytic gliomas.", "content": "Radiation therapy in the treatment of childhood astrocytic gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199356"} {"pmid": "4199360", "title": "An automated microbiological method for the measurement of vitamin B12.", "content": "An automated microbiological method for the measurement of vitamin B12. An automated method for the microbiological assay of vitamin B(12) is described. A chloramphenicol-resistant strain of Lactobacillus leichmannii is used as the test organism and this eliminates the need for sterilization or aseptic addition. Precipitation of the serum protein is avoided by dilution of the serum with a glutamic/malic acid solution before heating the preparation to free the vitamin B(12). Tests can be set up at a rate of 80 an hour and after incubation they can be read at 160 an hour. By interfacing a programmed electronic calculator directly with the Mecolab M which is used for the assays, results are printed directly in ng/l.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199360"} {"pmid": "4199361", "title": "Early detection of influenza virus in cell culture by means of immunofluorescence.", "content": "Early detection of influenza virus in cell culture by means of immunofluorescence. An indirect fluorescent antibody technique using human serum for the rapid detection of influenza A virus in monkey kidney cell cultures is described. Influenza A2 virus was isolated from 38 of 88 nose/throat swabs received from patients with suspected influenza during the winter of 1971-72.Thirty-two strains isolated in monkey kidney cell cultures were identified by immunofluorescence on the day haemadsorption was observed, 22 of them within a week of receipt of the specimen. Human antiserum was found to be very satisfactory for this purpose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199361"} {"pmid": "4199362", "title": "A rapid assay method for cephalosporins.", "content": "A rapid assay method for cephalosporins. A simple, rapid assay for cephalosporins is described. The method is based on the inhibition by cephalosporins of the fermentation of glucose or inositol by a strain of Providence resistant to aminoglycoside antibiotics. The method gives answers which are as accurate as those obtained by standard agar diffusion techniques within four hours, and utilizes skills and resources readily available in most routine bacteriology departments. Results are not affected by gentamicin or kanamycin concurrently administered to the patient. This method will be of value in helping to monitor cephalosporin therapy in patients with serious sepsis, especially those with impaired renal function, and may help in elucidating and preventing the problem of nephrotoxicity associated with cephalosporin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199362"} {"pmid": "4199363", "title": "Antithrombin-3 deficiency in a Dutch family.", "content": "Antithrombin-3 deficiency in a Dutch family. A Dutch family (family A) with inherited antithrombin-III deficiency and an increased incidence of venous thrombosis was investigated. Antithrombin-III levels were measured by means of a coagulation assay in plasma and by single radial immunodiffusion in plasma and serum.THREE GROUPS COULD BE DISTINGUISHED: group I comprised the relations-in-law of family A, group II the members of family A with a plasma antithrombin-III level higher than 90% of normal, when determined by the immunoassay, and group III the members of family A with an antithrombin-III level of less than 60%. To group III belonged all eight adults with an abnormal tendency to thrombosis, and furthermore nine children, all having a parent with abnormally low antithrombin-III levels. Mean plasma and serum antithrombin-III levels were significantly decreased in group III. However, the results of the coagulation assay showed some overlap between groups II and III. In addition, the immunoassay appeared to be much less laborious than the coagulation assay. Therefore, the former assay is recommended in any search for similar families. The results of our family investigation confirm the findings of Egeberg (1965) that inherited antithrombin-III deficiency, giving rise to plasma levels between 50 and 60% of normal, causes thrombophilia and that the pattern of inheritance is autosomal dominant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199363"} {"pmid": "4199364", "title": "The development of aluminum containers for the storage of blood in liquid nitrogen for the immunization of Rh volunteers.", "content": "The development of aluminum containers for the storage of blood in liquid nitrogen for the immunization of Rh volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199364"} {"pmid": "4199365", "title": "Alternation behaviour in the rhesus monkey after profound hypoxia.", "content": "Alternation behaviour in the rhesus monkey after profound hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199365"} {"pmid": "4199366", "title": "Relationships between luminance and visual acuity in the rhesus monkey.", "content": "Relationships between luminance and visual acuity in the rhesus monkey. 1. The ability of rhesus monkeys to detect the gap in Landolt ring test-objects that were presented against background luminances between 5 x 10(-5) cd/m(2) and 5 x 10(3) cd/m(2) was compared with similar human data.2. At high luminance-levels the acuity of human observers is slightly better than that of rhesus, but rhesus have better acuity at scotopic luminance-levels. Both species have distinct photopic and scotopic acuity functions that cross at 6 x 10(-3) cd/m(2).3. The threshold for light detection is estimated to be the same for both species when specified in quanta incident on the retina.4. It is concluded that the receptor and neural mechanisms that mediate visual-acuity function similarly in rhesus and man, and that the differences in acuity that were measured in the two species may be attributed to optical rather than to physiological factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199366"} {"pmid": "4199368", "title": "Serum sodium and potassium and blood glucose levels in cynamolgus monkeys after administration of melatonin.", "content": "Serum sodium and potassium and blood glucose levels in cynamolgus monkeys after administration of melatonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199368"} {"pmid": "4199369", "title": "Antigens of the male tract.", "content": "Antigens of the male tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199369"} {"pmid": "4199367", "title": "Potassium accumulation in smooth muscle and associated ultrastructural changes.", "content": "Potassium accumulation in smooth muscle and associated ultrastructural changes. 1. The water content, extracellular ((60)CoEDTA) space, ionic composition and ultrastructure of several mammalian smooth muscles were studied after incubation in solutions of varying ionic compositions and osmolarities.2. Substitution of KCl for NaCl resulted in an increase in cell water, K and Cl, accompanied by little change in total wet weight. This was due to a reduction in the extracellular space.3. Changes in extracellular osmolarity produced a wider range of cell volumes in high KCl solutions than in Krebs. The addition of 29-58 mM sucrose to high KCl prevented the swelling.4. Electron microscopy of smooth muscle swollen in high KCl solution revealed light (less electron opaque than normal) fibres of increased diameter, reduction in extracellular space, and nuclear swelling. The normal thick filament lattice was destroyed in swollen, osmium-fixed smooth muscles.5. The ultrastructural changes ascribed to swelling were absent in smooth muscles, (a) depolarized in high K(2)SO(4) solutions, (b) in high KCl solutions with 29-58 mM sucrose, and (c) returned to normal Krebs solution for recovery from swelling.6. Smooth muscles incubated in high KCl (swollen) and high K(2)SO(4) (unswollen) exhibited similar contractile responses, suggesting the filament lattice was intact until fixation, and that the contractile mechanism can operate over a relatively wide range of actin to myosin separations.7. Shrinkage of smooth muscles in high KCl solutions made hypertonic with the addition of 10% sucrose was accompanied by an aggregation of the thick filaments.8. The cell water of fixed taenia coli was reduced (a) by incubation in hypertonic solution followed by fixation in normal glutaraldehyde, or (b) by fixation of normal tissue in hypertonic glutaraldehyde. Osmotic responses during aldehyde fixation may be a source of artifact in the visualization of the normal filament lattice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199367"} {"pmid": "4199370", "title": "Lead poisoning in small animals.", "content": "Lead poisoning in small animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199370"} {"pmid": "4199374", "title": "Infantile hemiplegic disorder.", "content": "Infantile hemiplegic disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199374"} {"pmid": "4199380", "title": "Prolonged meningococcal septicemia. A report of four cases and a comparison with benign gonococcal septicemia.", "content": "Prolonged meningococcal septicemia. A report of four cases and a comparison with benign gonococcal septicemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199380"} {"pmid": "4199381", "title": "Five cases of meningitis due to sulfonamide-resistant meningococci.", "content": "Five cases of meningitis due to sulfonamide-resistant meningococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199381"} {"pmid": "4199384", "title": "Effect of synthetic thyrotrophin-releasing factor on pituitary TSH secretion in normal subjects and patients with hypothalamic-pituitary disorders.", "content": "Effect of synthetic thyrotrophin-releasing factor on pituitary TSH secretion in normal subjects and patients with hypothalamic-pituitary disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199384"} {"pmid": "4199382", "title": "Fixation and inactivation of cholera toxin by GM1 ganglioside.", "content": "Fixation and inactivation of cholera toxin by GM1 ganglioside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199382"} {"pmid": "4199385", "title": "Effect of thyrotrophin-releasing hormone on serum levels of pituitary hormones in men and women.", "content": "Effect of thyrotrophin-releasing hormone on serum levels of pituitary hormones in men and women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199385"} {"pmid": "4199390", "title": "Effect of incorporated 226Ra on colony forming units of bone marrow in splenectomized mice.", "content": "Effect of incorporated 226Ra on colony forming units of bone marrow in splenectomized mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199390"} {"pmid": "4199391", "title": "Carcinoma of the vulva. Results of an individualized treatment schedule.", "content": "Carcinoma of the vulva. Results of an individualized treatment schedule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199391"} {"pmid": "4199392", "title": "Stress electrocardiography in the evaluation of aortocoronary bypass surgery.", "content": "Stress electrocardiography in the evaluation of aortocoronary bypass surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199392"} {"pmid": "4199393", "title": "Tuberculoma of the heart. Report of 9 cases.", "content": "Tuberculoma of the heart. Report of 9 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199393"} {"pmid": "4199394", "title": "The value of warning arrhythmias in the prediction of ventricular fibrillation within one hour of coronary occlusion. Experimental studies in the baboon.", "content": "The value of warning arrhythmias in the prediction of ventricular fibrillation within one hour of coronary occlusion. Experimental studies in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199394"} {"pmid": "4199395", "title": "Metabolic studies on polychlorinated biphenyls. I. Metabolic fate of 3,4,3',4'-tetrachlorobiphenyl in rats.", "content": "Metabolic studies on polychlorinated biphenyls. I. Metabolic fate of 3,4,3',4'-tetrachlorobiphenyl in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199395"} {"pmid": "4199389", "title": "Albuminuria in acute and chronic renal failure.", "content": "Albuminuria in acute and chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199389"} {"pmid": "4199386", "title": "Disodium cromoglycate in bronchial asthma. A double-blind trial in adult patients.", "content": "Disodium cromoglycate in bronchial asthma. A double-blind trial in adult patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199386"} {"pmid": "4199388", "title": "The glomerular filtration rate during moderate hyperglycemia in normal man.", "content": "The glomerular filtration rate during moderate hyperglycemia in normal man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199388"} {"pmid": "4199387", "title": "Multiple myeloma with urinary excretion of heavy chain components of IgG and nodular glomerulosclerosis.", "content": "Multiple myeloma with urinary excretion of heavy chain components of IgG and nodular glomerulosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199387"} {"pmid": "4199400", "title": "The isolation of immunogenically pure IgM from Cohn fraction 3 of pooled normal human plasma.", "content": "The isolation of immunogenically pure IgM from Cohn fraction 3 of pooled normal human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199400"} {"pmid": "4199401", "title": "The association of the serum agglutinators with the fast IgG globulins.", "content": "The association of the serum agglutinators with the fast IgG globulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199401"} {"pmid": "4199402", "title": "Immunological studies on HeLa cell heat-stable alkaline phosphatases and their antigenic relationship with human placental and intestinal isoenzymes.", "content": "Immunological studies on HeLa cell heat-stable alkaline phosphatases and their antigenic relationship with human placental and intestinal isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199402"} {"pmid": "4199403", "title": "Sensitivity to reduction of human immunoglobulin G of different heavy chain sub-classes.", "content": "Sensitivity to reduction of human immunoglobulin G of different heavy chain sub-classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199403"} {"pmid": "4199404", "title": "Studies on sheep anti-human IgG antibodies and their sub-units.", "content": "Studies on sheep anti-human IgG antibodies and their sub-units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199404"} {"pmid": "4199405", "title": "The hydrolysis of rabbit immunoglobulin G with purified cathepsins D and E.", "content": "The hydrolysis of rabbit immunoglobulin G with purified cathepsins D and E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199405"} {"pmid": "4199406", "title": "Biochemical and immunological properties of low molecular weight constituents of Timothy pollen antigen.", "content": "Biochemical and immunological properties of low molecular weight constituents of Timothy pollen antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199406"} {"pmid": "4199407", "title": "The effect of disodium cromoglycate and PGF2 alpha on acute cutaneous reactions of the guinea pig and rat.", "content": "The effect of disodium cromoglycate and PGF2 alpha on acute cutaneous reactions of the guinea pig and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199407"} {"pmid": "4199408", "title": "Studies on the inhibition of cellular anaphylaxis.", "content": "Studies on the inhibition of cellular anaphylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199408"} {"pmid": "4199409", "title": "Intrinsic activation of plasma kinin formation and complement.", "content": "Intrinsic activation of plasma kinin formation and complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199409"} {"pmid": "4199410", "title": "Cellular and physiologic studies of immediate-type respiratory reactions.", "content": "Cellular and physiologic studies of immediate-type respiratory reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199410"} {"pmid": "4199411", "title": "Circulatory activity of a fully synthetic hydrogenated ergot alkaloid (DN 16-457).", "content": "Circulatory activity of a fully synthetic hydrogenated ergot alkaloid (DN 16-457).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199411"} {"pmid": "4199412", "title": "Defective mononuclear phagocyte function in patients with myelomonocytic leukemia and in some patients with lymphoma.", "content": "Defective mononuclear phagocyte function in patients with myelomonocytic leukemia and in some patients with lymphoma. Mononuclear phagocytes from 8 of 10 patients with myelomonocytic leukemia and 2 of 9 patients with lymphoma phagocytized several species of bacteria but did not inhibit intracellular bacterial replication normally. Intracellular organisms were protected from the lethal effects of antibiotics in the medium. This defect of microbicidal function of malignant monocytes may explain in part the frequency of infection and the mechanism of antibiotic-resistant infection in some patients with malignant myeloproliferative and lymphoproliferative diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199412"} {"pmid": "4199413", "title": "Studies on the nature of antihemophilic factor (factor VIII). Further evidence relating the AHF-like antigens in normal and hemophilic plasmas.", "content": "Studies on the nature of antihemophilic factor (factor VIII). Further evidence relating the AHF-like antigens in normal and hemophilic plasmas. Normal human antihemophilic factor (AHF, factor VIII) and the protein antigenically related to it in hemophilic plasma both appeared in the void volume of columns of agarose (Sepharose 4B) during purification of these agents. On ultracentrifugation upon sucrose gradients, both agents had sedimentation characteristics similar to those of an S30 marker. After reduction, the polypeptide chains of purified normal AHF and of the nonfunctional agent from hemophilic patients had an apparent molecular weight of 200,000 as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis. These observations suggest that AHF, purified as described, exists as a large molecule with subunits of molecular weight of approximately 200,000. Antisera to normal AHF and the nonfunctional agent from hemophilic plasma appeared to be directed against antigens of similar electrophoretic mobility and precipitating characteristics, present in normal and hemophilic plasma but deficient in severe von Willebrand's disease plasma. Both antisera neutralized the AHF clot-promoting activity present in normal plasma, and this property was removed by absorption of the antisera with concentrates of normal or hemophilic plasma but to a greatly reduced extent by concentrates of von Willebrand's disease plasma. These findings suggest that the antigen detected in normal plasma by the antisera appears on a molecule participating in the AHF clot-promoting reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199413"} {"pmid": "4199415", "title": "Immunology of the lower respiratory tract. Functional properties of bronchoalveolar lymphocytes obtained from the normal canine lung.", "content": "Immunology of the lower respiratory tract. Functional properties of bronchoalveolar lymphocytes obtained from the normal canine lung. While the alveolar macrophage has been studied extensively, little attention has been directed toward the immune functions of the bronchoalveolar lymphocyte. These cells, obtained by bronchopulmonary lavage of the normal canine lung, are derived from the air side of the alveolar-capillary membrane of the lower respiratory tract. The distribution of lymphocyte types within the bronchoalveolar cell population was determined and compared with that of leukocytes from blood and spleen.IgG synthesis in vitro was used as a measure of bone marrow-derived lymphocyte (B cell) function, and the blastogenic response of cell cultures to phytohemagglutinin was used as a measure of the presence or absence of thymus-dependent lymphocytes (T cells). De novo synthesis of IgG by bronchoalveolar cells was demonstrated consistently by two independent radio-immunoassays. Therefore, B cells are present in the air spaces of normal canine lungs. T cells were generally not detectable in aliquots of the same cell populations but could be recruited into alveolar spaces after local irritation. The distribution of lymphocyte types within the bronchoalveolar cell population is unique and distinctly different from that of blood and spleen. The spleen is rich in both T cells and B cells, blood is rich in T cells but poor in B cells, whereas the lung lacks T cells and contains substantial numbers of immunoglobulin-producing B cells. The findings indicate that bronchoalveolar lymphocytes do not reflect simply the lymphoid composition of peripheral blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199415"} {"pmid": "4199414", "title": "The subunit structure of normal and hemophilic factor VIII.", "content": "The subunit structure of normal and hemophilic factor VIII. Human factor VIII from normals and hemophiliacs was partially purified by ethanol and polyethylene glycol precipitations. Final purification was achieved by gel filtration on 2 or 4% agarose or ion exchange chromatography on diethylaminoethyl cellulose. Comparable amounts of highly purified protein were obtained from normal and hemophilic plasma following the agarose chromatography step. Highly purified factor VIII was not dissociated by 6 M guanidine hydrochloride or 1% sodium dodecyl sulfate. However, when reduced by beta-mercaptoethanol and analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis, a single subunit species with an estimated 195,000 molecular weight was found for both normal and hemophilic factor VIII. By sedimentation equilibrium analysis, the normal factor VIII subunit was homogeneous and had an estimated molecular weight of 202,000. The subunit polypeptides from normal or hemophilic factor VIII contained carbohydrate. Each was homogeneous by isoelectric focusing. Immunodiffusion of purified normal and hemophilic factor VIII against rabbit antiserum to purified normal human factor VIII showed a single line of precipitation. Very low concentrations of purified human thrombin initially increased the activity of normal factor VIII about threefold and then progressively destroyed activity by 3 h. Only minimal activation occurred with hemophilic factor VIII. Both the activation and inactivation of normal and hemophilic factor VIII were unaccompanied by detectable changes in subunit molecular weight. These findings may have implications for the definition of the molecular defect in hemophilic factor VIII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199414"} {"pmid": "4199417", "title": "Repetitive administration of thyrotropin-releasing hormone results in small elevations of serum thyroid hormones and in marked inhibition of thyrotropin response.", "content": "Repetitive administration of thyrotropin-releasing hormone results in small elevations of serum thyroid hormones and in marked inhibition of thyrotropin response. Repetitive administration of thyrotropin-releasing hormone (TRH) to human subjects was used to produce small elevations of endogenous serum triiodothyronine (T(3)) and thyroxine (T(4)) levels and thereby to determine the effect of these small elevations on the serum thyrotropin (TSH) response to subsequent doses of TRH. Each subject received 13 consecutive doses of 25 mug TRH at 4-h intervals. Serum T(3), T(4), and TSH levels were measured before the 1st, 7th, and 13th doses (\"basal levels\") and for the 4 h after each of these doses. In 10 normal subjects, the mean TSH response fell from 14.6 muU/ml after the 1st TRH dose to 6.9 and 3.0 muU/ml after the 7th, and 13th doses. These falls in TSH response were accompanied by rises in the mean basal serum T(3) levels from 81 to 115 to 114 ng/100 ml (normal range, 70-150 ng/100 ml) and rises in the mean basal serum T(4) from 6.7 to 8.6 to 9.5 mug/100 ml (normal range, 5-11 mug/100 ml). These data suggest that TRH-induced TSH release is extremely sensitive to inhibition by small elevations, not above the normal ranges, of serum T(3) and T(4) of endogenous origin. In four patients with primary hypothyroidism, the mean TSH responses were 92, 137, and 92 muU/ml after the 1st, 7th, and 13th TRH doses. The corresponding mean basal serum T(3) and T(4) levels at the times of these doses were 34, 30, and 32 ng/100 ml and 1.9, 1.9, and 1.7 mug/100 ml. These data show that repetitive administration of TRH does not result in progressively lower TSH responses in the absence of corresponding increases in serum T(3) and T(4) level. The progressive fall in TSH response observed in the normal subjects, therefore, was apparently due to the corresponding small increases in serum T(3) and T(4) levels and not to progressive depletion of pituitary TSH. In two patients with presumed TRH deficiency, the TSH responses were blunted by repetitive TRH doses but only when the serum T(3) and T(4) levels increased to within the normal ranges. TRH deficiency was thus confirmed for the first time by producing euthyroidism by replacement of TRH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199417"} {"pmid": "4199416", "title": "Effective erythropoiesis induced by 5beta-pregnane-3beta-hydroxy-20-one in squirrel monkeys.", "content": "Effective erythropoiesis induced by 5beta-pregnane-3beta-hydroxy-20-one in squirrel monkeys. The erythropoietic effect of 5beta-pregnane-3beta-hydroxy-20-one, a naturally occurring steroid metabolite of progesterone, was evaluated in the squirrel monkey by ferrokinetic studies. red cell survival, and blood volume measurements. The intramuscular administration of this steroid in pharmacologic doses shortened the (59)Fe plasma clearance and increased the plasma iron turnover, thereby indicating an increase in erythropoiesis. A normal (59)Fe red cell uptake was observed, and the bone marrow maturation time was not altered. Red cell survival was the same in the treated and control groups. After five weekly injections of the steroid, the monkeys increased their red cell mass by 57%. A significant increase in white blood cells and a slight elevation of platelet counts in the treated monkeys also suggest a possible direct stimulation of hemopoietic stem cells by the steroid metabolite. These observations indicate that some steroid metabolites can stimulate an early increase in iron turnover (within 48 h) that is not secondary to hemolysis. The increased red cell mass indicates effective erythropoiesis in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199416"} {"pmid": "4199418", "title": "Thyroid hormone inhibition of the prolactin response to thyrotropin-releasing hormone.", "content": "Thyroid hormone inhibition of the prolactin response to thyrotropin-releasing hormone. The influence of serum triiodothyronine (T(3)) and thyroxine (T(4)) concentrations on the release of prolactin in man was studied by determining the prolactin response to synthetic thyrotropin-releasing hormone (TRH) in hypothyroid and hyperthyroid patients before and after correction of their serum thyroid hormone abnormalities. The maximum increment in serum prolactin above the basal level (maximum Delta prolactin) was used as the index of response to TRH. In 12 patients with primary hypothyroidism, the maximum Delta prolactin in response to TRH fell from 100.5+/-29.1 ng/ml (mean +/-SEM) before treatment to 36.1+/-6.0 ng/ml (P < 0.01) during the 4th wk of treatment with 30 mug T(3) + 120 mug T(4) daily. The mean serum T(3) level increased from 57+/-8 to 138+/-10 ng/100 ml, and the mean serum T(4) level increased from 3.0+/-0.4 to 7.2+/-0.4 mug/100 ml during this treatment. In eight normal subjects the maximum Deltaprolactin in response to TRH was not significantly different during the 4th wk of treatment with 30 mug T(3) + 120 mug T(4) daily from the response before treatment. In 10 patients with hyperthyroidism, the maximum Deltaprolactin in response to TRH increased from 14.2+/-2.9 ng/ml before treatment to 46.9+/-6.7 ng/ml (P < 0.001) during antithyroid treatment. The mean serum T(3) level fell from 313+/-47 to 90+/-8 ng/100 ml, and the mean serum T(4) level fell from 20.8+/-2.5 to 6.8+/-0.6 mug/100 ml during this treatment. These results show that changes from normal serum levels of T(3) and T(4) are associated with changes in prolactin responses to TRH; subnormal serum levels of T(3) and T(4) increase TRH-induced prolactin release, whereas substantially higher than normal serum levels of T(3) and T(4) inhibit this release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199418"} {"pmid": "4199423", "title": "Stimulation of nonimmunized lymphocytes by platelet-antibody complexes in idiopathic thrombocytopenic purpura.", "content": "Stimulation of nonimmunized lymphocytes by platelet-antibody complexes in idiopathic thrombocytopenic purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199423"} {"pmid": "4199431", "title": "Lysine supplementation of wheat gluten at adequate and restricted energy intakes in young men.", "content": "Lysine supplementation of wheat gluten at adequate and restricted energy intakes in young men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199431"} {"pmid": "4199432", "title": "Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. I. A functional defect in hepatic retinol release.", "content": "Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. I. A functional defect in hepatic retinol release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199432"} {"pmid": "4199433", "title": "Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. II. Treatment including supplemental vitamin A.", "content": "Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. II. Treatment including supplemental vitamin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199433"} {"pmid": "4199434", "title": "Effects of chromium supplementation on growth in marasmic protein--calorie malnutrition.", "content": "Effects of chromium supplementation on growth in marasmic protein--calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199434"} {"pmid": "4199435", "title": "Endotoxin-induced protection against experimental Junín virus infection.", "content": "Endotoxin-induced protection against experimental Junín virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199435"} {"pmid": "4199436", "title": "Effect of eight fungicides on microbial activities in soil as measured by a bioassay method.", "content": "Effect of eight fungicides on microbial activities in soil as measured by a bioassay method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199436"} {"pmid": "4199437", "title": "Ultrastructural changes in the midgut epithelium of an elaterid larva (Coleoptera) infected enterically with Pseudomonas aeruginosa.", "content": "Ultrastructural changes in the midgut epithelium of an elaterid larva (Coleoptera) infected enterically with Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199437"} {"pmid": "4199438", "title": "Electron microscope and physical chemical characterization of C-phycocyanin from fresh extracts of two blue-green algae.", "content": "Electron microscope and physical chemical characterization of C-phycocyanin from fresh extracts of two blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199438"} {"pmid": "4199439", "title": "Association of virulence characteristics of Erwinia amylovora with toxigenicity of its phage lysates to rabbit.", "content": "Association of virulence characteristics of Erwinia amylovora with toxigenicity of its phage lysates to rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199439"} {"pmid": "4199456", "title": "Nutritional status of patients after extended tube feeding.", "content": "Nutritional status of patients after extended tube feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199456"} {"pmid": "4199457", "title": "Responses of the bovine lymphatic system to infection by Theileria parva. I. Histology and ultrastructure of lymph nodes in experimentally-infected calves.", "content": "Responses of the bovine lymphatic system to infection by Theileria parva. I. Histology and ultrastructure of lymph nodes in experimentally-infected calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199457"} {"pmid": "4199458", "title": "Responses of the bovine lymphatic system to infection by Theileria parva. II. Changes in the central lymph in experimentally-infected calves.", "content": "Responses of the bovine lymphatic system to infection by Theileria parva. II. Changes in the central lymph in experimentally-infected calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199458"} {"pmid": "4199459", "title": "Immunization against Brucella infections. Priming of Cynomolgus philipinensis with purified antigen of Brucella melitensis prior to injection of Rev. I vaccine.", "content": "Immunization against Brucella infections. Priming of Cynomolgus philipinensis with purified antigen of Brucella melitensis prior to injection of Rev. I vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199459"} {"pmid": "4199460", "title": "A colorimetric method for measurement of the (peroxidase-mediated) oxidation of 3,3'-diaminobenzidine.", "content": "A colorimetric method for measurement of the (peroxidase-mediated) oxidation of 3,3'-diaminobenzidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199460"} {"pmid": "4199461", "title": "Inability of murine melanoma \"tyrosinase\" (dopa ozidase) to oxidize tyrosine in the presence or absence of dopa or dihydroxyfumarate cofactor.", "content": "Inability of murine melanoma \"tyrosinase\" (dopa ozidase) to oxidize tyrosine in the presence or absence of dopa or dihydroxyfumarate cofactor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199461"} {"pmid": "4199462", "title": "Fixation effects on the fine structure of enamel crystal-matrix relationships.", "content": "Fixation effects on the fine structure of enamel crystal-matrix relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199462"} {"pmid": "4199463", "title": "Preliminary study of B. subtilis alpha-amylase crystals by electron microscopy and optical diffraction.", "content": "Preliminary study of B. subtilis alpha-amylase crystals by electron microscopy and optical diffraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199463"} {"pmid": "4199464", "title": "Microcirculation and metabolism in the vascular wall concerned with the vasa vasorum.", "content": "Microcirculation and metabolism in the vascular wall concerned with the vasa vasorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199464"} {"pmid": "4199465", "title": "Absence of cross-reactive antigen in Fabry's disease.", "content": "Absence of cross-reactive antigen in Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199465"} {"pmid": "4199466", "title": "Anticonvulsants and fetal damage.", "content": "Anticonvulsants and fetal damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199466"} {"pmid": "4199472", "title": "Wilson's disease in the United Kingdom and Taiwan. I. General characteristics of 142 cases and prognosis. II. A genetic analysis of 88 cases.", "content": "Wilson's disease in the United Kingdom and Taiwan. I. General characteristics of 142 cases and prognosis. II. A genetic analysis of 88 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199472"} {"pmid": "4199474", "title": "Comparison of acute oral toxicity of cannabinoids in rats, dogs and monkeys.", "content": "Comparison of acute oral toxicity of cannabinoids in rats, dogs and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199474"} {"pmid": "4199475", "title": "Fish bile analysis: a possible aid in monitoring water quality.", "content": "Fish bile analysis: a possible aid in monitoring water quality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199475"} {"pmid": "4199481", "title": "Extraction of carboxylic acids as adducts with dibenzo-18-crown-6.", "content": "Extraction of carboxylic acids as adducts with dibenzo-18-crown-6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199481"} {"pmid": "4199482", "title": "Intraarterial administration of emulsion formulations containing cyclandelate and nitroglycerin.", "content": "Intraarterial administration of emulsion formulations containing cyclandelate and nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199482"} {"pmid": "4199483", "title": "Preparation of protein-steroid conjugates and antisera against oestradiol-17 .", "content": "Preparation of protein-steroid conjugates and antisera against oestradiol-17 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199483"} {"pmid": "4199484", "title": "Micrococcus indolicus. Some biochemical properties, and the demonstration of sex antigenically different types.", "content": "Micrococcus indolicus. Some biochemical properties, and the demonstration of sex antigenically different types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199484"} {"pmid": "4199486", "title": "Clinical aspects of Rh immunization. Philip Levine Award Address.", "content": "Clinical aspects of Rh immunization. Philip Levine Award Address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199486"} {"pmid": "4199485", "title": "Levels of polychlorinated biphenyls (PCB) and organochlorine insecticides in eggs from eider (Somateria mollissima).", "content": "Levels of polychlorinated biphenyls (PCB) and organochlorine insecticides in eggs from eider (Somateria mollissima).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199485"} {"pmid": "4199476", "title": "Ocular manifestations of dwarfism.", "content": "Ocular manifestations of dwarfism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199476"} {"pmid": "4199488", "title": "Long-term continuous exposure to sulfur dioxide and fly ash mixtures in cynomolgus monkeys and guinea pigs.", "content": "Long-term continuous exposure to sulfur dioxide and fly ash mixtures in cynomolgus monkeys and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199488"} {"pmid": "4199490", "title": "The effect of a combined preparation of trimethoprim and sulphamethoxazole following short-term and long-term administration on the flora of the human gut.", "content": "The effect of a combined preparation of trimethoprim and sulphamethoxazole following short-term and long-term administration on the flora of the human gut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199490"} {"pmid": "4199491", "title": "Factors in the pathogenesis of experimental nonketotic and ketoacidotic diabetic stupor.", "content": "Factors in the pathogenesis of experimental nonketotic and ketoacidotic diabetic stupor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199491"} {"pmid": "4199494", "title": "Levels of serum LH in rhesus monkeys after intrapituitary infusion of synthetic LH-RH or median eminence extracts.", "content": "Levels of serum LH in rhesus monkeys after intrapituitary infusion of synthetic LH-RH or median eminence extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199494"} {"pmid": "4199495", "title": "Effect of immunization with estrone-protein conjugate in rhesus monkeys.", "content": "Effect of immunization with estrone-protein conjugate in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199495"} {"pmid": "4199493", "title": "Effects of cations and colchicine on the release of prolactin and growth hormone by functional pituitary tumor cells in culture.", "content": "Effects of cations and colchicine on the release of prolactin and growth hormone by functional pituitary tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199493"} {"pmid": "4199496", "title": "The influence of lactation on luteal function in the rhesus monkey.", "content": "The influence of lactation on luteal function in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199496"} {"pmid": "4199497", "title": "The metabolism of saccharin in laboratory animals.", "content": "The metabolism of saccharin in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199497"} {"pmid": "4199498", "title": "Polychlorinated biphenyls: evidence of transplacental passage in the Sherman rat.", "content": "Polychlorinated biphenyls: evidence of transplacental passage in the Sherman rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199498"} {"pmid": "4199489", "title": "An investigation into the mode of transmission of sarcosporidiosis.", "content": "An investigation into the mode of transmission of sarcosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199489"} {"pmid": "4199500", "title": "Normal development of the jaws and teeth in pigs, and the delay and malocclusion produced by calorie deficiencies.", "content": "Normal development of the jaws and teeth in pigs, and the delay and malocclusion produced by calorie deficiencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199500"} {"pmid": "4199501", "title": "The innervation of the cerebral arteries.", "content": "The innervation of the cerebral arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199501"} {"pmid": "4199503", "title": "Penicillinases of Klebsiella pneumoniae and their phylogenetic relationship to penicillinases mediated by R factors.", "content": "Penicillinases of Klebsiella pneumoniae and their phylogenetic relationship to penicillinases mediated by R factors. On the assumption that the penicillinase determinants on a group of R factors conferring ampicillin resistance have a phylogenetically close relationship to the penicillinase gene of the Klebsiella group, the penicillinases from four strains of K. pneumoniae, GN69, GN1103R(-), GN422, and GN118, were purified 230- to 1,000-fold and compared with the known two R-factor-mediated penicillinases. By gel filtration on Sephadex G-75, the molecular weights were estimated to be 17,400, 18,100, 20,000 and 18,300, respectively, which are slightly lower than those of the R-factor penicillinases. The isoelectric points of the Klebsiella penicillinases were not in agreement with those of the R-factor penicillinases. All the enzymes showed a pH optimum between 6.3 to 7.2 and a temperature optimum of 45 C, and those properties, together with behavior towards inhibitors, were about the same as those in the R-factor penicillinases. The substrate specificity and the Michaelis constants of the Klebsiella penicillinases for penicillins and cephaloridine were broadly similar to those of the R-factor penicillinases, however, some variations were found even among the four penicillinases of K. pneumoniae. The reactivities of the four penicillinases of K. pneumoniae with the antiserum against one R-factor penicillinase were tested, and three of the four Klebsiella penicillinases were found to be indistinguishable immunologically from both R-factor penicillinases. The remaining Klebsiella penicillinase, from GN1103R(-), showed an immunological partial homology with the R-factor penicillinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199503"} {"pmid": "4199502", "title": "Pleiotropic menaquinone-deficient mutant of Bacillus subtilis.", "content": "Pleiotropic menaquinone-deficient mutant of Bacillus subtilis. A multiple aromatic amino acid auxotroph of Bacillus subtilis 168 has been isolated which is unable to synthesize menaquinone-7 (MK-7) unless supplied with shikimic acid (SHK). The mutant, RB163, was isolated by selecting for resistance to low levels (1.5 mug/ml) of kanamycin. Enzymatic and genetic analyses show that the strain is an aroD mutant lacking 5-dehydroshikimate reductase. Under growth conditions in which its MK-7 deficiency is expressed, RB163 is deficient in cytochromes a, b, and c, exhibits low growth yields, and does not sporulate. Genetic analysis indicates that this pleiotropic phenotype is the result of a single genetic event. All phenotypic characteristics are reversible when the mutant is grown under conditions such that MK is synthesized. Comparison of strain RB163 with other aro mutants blocked before SHK (\"early-aro\" mutants) reveals interesting differences. Most early-aro mutants are cytochrome- and MK-sufficient, sporogenous, and sensitive to kanamycin when grown in the absence of SHK. However, in addition to strain RB163, two other aro mutants were found to show the pleiotropic phenotype. These three mutants have in common, and differ from other early-aro strains in, the inability to synthesize MK. It is suggested that the phenotypically wild-type aro mutants are bradytrophic, allowing enough substrate flow through the common aromatic pathway to satisfy the MK requirement. The pleiotropic mutants are thought to be completely blocked in the common pathway, thus accounting for their inability to synthesize MK.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199502"} {"pmid": "4199504", "title": "Phenotypes of pleiotropic-negative sporulation mutants of Bacillus subtilis.", "content": "Phenotypes of pleiotropic-negative sporulation mutants of Bacillus subtilis. The phenotypic properties of representatives of the five genetic classes of pleiotropic-negative sporulation mutants have been investigated. Protease production, alkaline and neutral proteases, was curtailed in spoA mutants, but the remainder of mutant classes produced both proteases, albeit at reduced levels. The spoA and spoB mutants plaqued phi2 and phi15 at high efficiency, but the efficiency of plating of these phages on spoE, spoF, and spoH mutants was drastically reduced. Antibiotic was produced by the spoH mutants and to a degree by some spoF mutants, but the other classes did not produce detectable activity. The spoA mutants were less responsive to catabolite repression of histidase synthesis by glucose than was the wild type. Severe catabolite repression could be induced in spoA mutants by amino acid limitation, suggesting that the relaxation of catabolite repression observed is not due to a defect in the mechanism of catabolite repression. Although others have shown a perturbation in cytochrome regulation in spoA and spoB mutants, the primary dehydrogenases, succinate dehydrogenase and reduced nicotinamide adenine dinucleotide dehydrogenase, leading to these cytochromes are unimpaired in all mutant classes. A comparison of the structural components of cell walls and membranes of spoA and the wild type is made. The pleiotropic phenotypes of these mutants are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199504"} {"pmid": "4199506", "title": "Deoxyribonucleic acid-deoxyribonucleic acid hybridization of R factors.", "content": "Deoxyribonucleic acid-deoxyribonucleic acid hybridization of R factors. A new method of estimating deoxyribonucleic acid homology is presented and used to measure the homology between bacterial plasmids of different compatibility groups. Deoxyribonucleic acid of the P-group plasmid RP1, originally isolated in Pseudomonas aeruginosa, has considerable (50%) homology with an N-group plasmid of the Enterobacteriaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199506"} {"pmid": "4199505", "title": "Ethidium bromide-resistant mutant of Bacillus subtilis.", "content": "Ethidium bromide-resistant mutant of Bacillus subtilis. An ethidium bromide-resistant mutant (EB8) derived from a Marburg strain of Bacillus subtilis was found to be conditionally resistant to 10 mug of ethidium bromide per ml. Expression of resistance is complete only during vegetative growth at incubation temperatures above 30 C in complex medium or minimal medium supplemented with Casamino Acids. Strain EB8 is cross-resistant to acriflavine and proflavine. The ethidium bromide resistance marker is co-transduced with hisA1 at a frequency of 6% and is located to the right of hisA1 on the B. subtilis chromosome as it is usually represented on the map. Incorporation of [5-(3)H] uridine by strain EB8 showed that ribonucleic acid synthesis in both whole cells and protoplasts is ethidium bromide-resistant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199505"} {"pmid": "4199508", "title": "Exosporium and spore coat formation in Bacillus cereus T.", "content": "Exosporium and spore coat formation in Bacillus cereus T. The exosporium of Bacillus cereus T was first observed as a small lamella in the cytoplasm in proximity to the outer forespore membrane (OFSM) near the middle of the sporangium. Serial sections, various staining methods, and enzyme treatments failed to show any connections between the small lamella and the OFSM. The advancing edge of the exosporium moved toward the polar end of the cell until the spore was completely enveloped. The middle coat was formed between the exosporium and the OFSM from a three-layered single plate or \"belt,\" consisting of two electron-dense layers separated by an electron-transparent layer. This \"belt,\" usually first observed toward the center of the sporangium, developed without changing thickness or appearance over the surface of the forespore. Between the middle coat and the OFSM, a layer of cytoplasm about 50-nm thick was enclosed by the developing coat; this became the inner coat. Electron-dense material was deposited on the outer surface of the middle coat to form the outer coat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199508"} {"pmid": "4199507", "title": "Release and recovery of forespores from Bacillus cereus.", "content": "Release and recovery of forespores from Bacillus cereus. A method is described which makes possible the release of immature forespores from sporulating cells at specific stages of development, from the completion of stage III through to mature spore formation. With the aid of zonal density gradient centrifugation, the method makes possible the recovery of quantities of forespores ample for biochemical and physical studies. With the capability to examine forespores and some mother cell components independently, we have established that several enzymes associated with the sporulation process are localized in the newly developed forespores. Studies showed that aspartate aminotransferase and alanine aminotransferase are associated with the forespores, whereas l-alanine dehydrogenase is found only in the mother cell cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199507"} {"pmid": "4199510", "title": "Genetic mapping of a mutant defective in D,L-alanine racemase in Bacillus subtilis 168.", "content": "Genetic mapping of a mutant defective in D,L-alanine racemase in Bacillus subtilis 168. Genetic analysis of a d-alanine requiring mutant (dal) of Bacillus subtilis reveals that the gene that codes for d,l-alanine racemase is linked to purB. The order of genes in this region of the chromosome is purB, pig, tsi, dal. Thus there are at least two clusters of genes that regulate cell wall biosynthesis in B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199510"} {"pmid": "4199509", "title": "Rapid method for isolation of large quantities of outer membrane from Escherichia coli K-12 and its application to the study of envelope mutants.", "content": "Rapid method for isolation of large quantities of outer membrane from Escherichia coli K-12 and its application to the study of envelope mutants. A rapid method for the isolation of large quantities of bacterial outer membrane is described. This cell envelope component was removed from plasmolyzed cells of Escherichia coli K-12 by lysozyme-ethylenediaminetetra-acetic acid treatment, aggregated by lowering the pH to 5.0, and recovered by centrifugation. Aggregates of membrane fragments were clearly identified in an electron microscope. A criterion of homogeneity of the preparation was obtained by isopycnic sucrose gradient centrifugation. A single band appeared at a density of 1.24 g/cc. The cytoplasmic membrane marker, succinate dehydrogenase activity, was 40 times lower in the outer membrane preparation than in complete cell envelope preparations. A rich activity was, however, found for the outer membrane marker, phospholipase A. The compositions of outer membranes from a transductant pair were compared. One transductant was a chain-forming, antibiotic-supersensitive envA strain, whereas the other contained the envA(+) allele. The envA strain showed a slightly modified protein pattern and a lower relative content of phosphatidylglycerol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199509"} {"pmid": "4199511", "title": "Effect of biogenic amines and cannabinoids on bacterial chemotaxis.", "content": "Effect of biogenic amines and cannabinoids on bacterial chemotaxis. The chemotactic response of Pseudomonas fluorescens was significantly enhanced by the stimulants dl-amphetamine and epinephrine. Acetylcholine, a physiological antagonist of epinephrine, and the cannabinoid tetrahydrocannabinol inhibited bacterial chemotaxis. It may be possible to use bacterial chemotaxis as a bioassay in biochemical studies of drug action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199511"} {"pmid": "4199512", "title": "Genetic and biochemical characterization of mutants of Bacillus subtilis defective in succinate dehydrogenase.", "content": "Genetic and biochemical characterization of mutants of Bacillus subtilis defective in succinate dehydrogenase. Eleven succinate-accumulating mutants of Bacillus subtilis have been mapped by transformation and transduction crosses and characterized with respect to activities of citric acid cycle enzymes. These mutants could be divided into three genetic groups. Nine of the mutants were found to map between argA and leu in the citF locus. A second group was located between lys-1 and trpC2 and the third group could not be located on the B. subtilis chromosome in extensive transduction crosses. All of the citF mutants lack detectable succinate dehydrogenase activity, whereas both of the other groups show a reduced level of this enzyme. In addition, most of the mutants in the citF locus lack cytochrome a, whereas the level of this cytochrome is normal in the other two groups. A procedure has been devised for the solubilization of the succinate dehydrogenase from the membrane of B. subtilis with the non-ionic detergent Brij 58. Some properties of the soluble and bound forms of succinate dehydrogenase are described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199512"} {"pmid": "4199513", "title": "Threonine synthetase-catalyzed conversion of phosphohomoserine to alpha-ketobutyrate in Bacillus subtilis.", "content": "Threonine synthetase-catalyzed conversion of phosphohomoserine to alpha-ketobutyrate in Bacillus subtilis. An enzyme activity of Bacillus subtilis has been found that catalyzes the dephosphorylation and deamination of phosphohomoserine to alpha-ketobutyrate, resulting in a bypass of threonine in isoleucine biosynthesis. In crude extracts of a strain deficient in the biosynthetic isoleucine-inhibitable threonine dehydratase, phosphohomoserine was converted to alpha-ketobutyrate. Phosphohomoserine conversion to alpha-ketobutyrate was shown not to involve a threonine intermediate. Single mutational events affecting threonine synthetase also affected the phosphohomoserine-deaminating activity, suggesting that the deamination of phosphohomoserine was catalyzed by the threonine synthetase enzyme. It was demonstrated in vivo, in a strain deficient in the biosynthetic threonine dehydratase, that isoleucine was synthesized from homoserine without intermediate formation of threonine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199513"} {"pmid": "4199514", "title": "Transduction of lactose metabolism in Streptococcus lactis C2.", "content": "Transduction of lactose metabolism in Streptococcus lactis C2. Ultraviolet (UV)-induced phage lysates, from lactose-positive (lac(+)) Streptococcus lactis C2, transduced lactose fermenting ability to lac(-) recipient cells of this organism. Although the phage titer could not be determined due to the absence of an appropriate indicator strain, the number of transductants was proportional to the amount of phage lysate added. Treatment of the lysate with deoxyribonuclease had no effect on this conversion, indicating the observed genetic change was not mediated by free deoxyribonucleic acid. When the lac(+) transductants were isolated and exposed to UV irradiation, lysates with higher transducing ability were obtained. The transducing ability of this lysate was about 100-fold higher than that observed in the original lysates. The lac(+) transductants were unstable since lac(-) segregants occurred at high frequency. The phage lysate from S. lactis C2 also transduced maltose and mannose metabolism to the respective negative recipient cells. The results demonstrate the transduction of carbohydrate markers by a streptococcal phage and establish a genetic transfer system in group N streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199514"} {"pmid": "4199515", "title": "Lipopolysaccharide layer protection of gram-negative bacteria against inhibition by long-chain fatty acids.", "content": "Lipopolysaccharide layer protection of gram-negative bacteria against inhibition by long-chain fatty acids. Growth, amino acid transport, and oxygen consumption of Escherichia coli and Salmonella typhimurium are inhibited by short-chain (C(2)-C(6)) but not by medium or long-chain fatty acids (C(10)-C(18)) at concentrations at which these processes are completely inhibited in Bacillus subtilis. The resistance of gram-negative organisms is not correlated with their ability to metabolize fatty acids, since an E. coli mutant unable to transport oleic acid is still resistant. However, mutants of both E. coli and S. typhimurium in which the lipopolysaccharide layer does not contain the residues beyond the 2-keto-3-deoxyoctonate core are inhibited by medium (C(10)) but not by long-chain (C(18)) fatty acids. Furthermore, removal of a portion of the lipopolysaccharide layer by ethylenediaminetetraacetate treatment renders the organisms sensitive to medium and partially sensitive to long-chain fatty acids. The intact lipopolysaccharide layer of gram-negative organisms apparently screens the cells against medium and long-chain fatty acids and prevents their accumulation on the inner cell membrane (site of amino acid transport) at inhibitory concentrations. These results are relevant to the use of antimicrobial food additives, and they allow the characterization of gram-positive versus gram-negative bacteria and their lipopolysaccharide mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199515"} {"pmid": "4199516", "title": "Hydroxamate recognition during iron transport from hydroxamate-ion chelates.", "content": "Hydroxamate recognition during iron transport from hydroxamate-ion chelates. Kinetics of radioactive iron transport from three structurally different secondary hydroxamate-iron chelates (schizokinen-iron, produced by Bacillus megaterium ATCC 19213; Desferal-iron, produced by an actinomycete; and aerobactin-iron, produced by Aerobacter aerogenes 62-1) revealed that B. megaterium SK11 (a mutant which cannot synthesize schizokinen) has a specific transport system for utilization of ferric hydroxamates with a recognition capacity based on the chemical structure of the hydroxamate. Both Desferal and schizokinen enhanced iron uptake in this organism; however, Desferal-iron delivered only one-sixth the level of iron incorporated from the schizokinen-iron chelate. Desferal-iron did not generate the rapid rates of iron transport noted with schizokinen-iron at elevated iron concentrations. Assays containing large excesses of either iron-free Desferal or iron-free schizokinen suggested that the iron-free hydroxamate may compete with the ferric hydroxamate for acceptance by the transport system although the system has greater affinity for the iron chelate. Aerobactin-iron did not stimulate iron uptake in B. megaterium SK11 and aerobactin inhibited growth of this organism, indicating that B. megaterium SK11 cannot efficiently process the aerobactin-iron chelate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199516"} {"pmid": "4199517", "title": "Fate of labeled hydroxamates during iron transport from hydroxamate-ion chelates.", "content": "Fate of labeled hydroxamates during iron transport from hydroxamate-ion chelates. The fate of the hydroxamic acid-iron transport cofactors during iron uptake from the (59)Fe(3+) chelates of the (3)H-labeled hydroxamates schizokinen and aerobactin was studied by assay of simultaneous incorporation of both (59)Fe(3+) and (3)H. In the schizokinen-producing organism Bacillus megaterium ATCC 19213 transport of (59)Fe(3+) from the (3)H-schizokinen-(59)Fe(3+) chelate at 37 C was accompanied by rapid uptake and release (within 2 min) of (3)H-schizokinen, although (3)H-schizokinen discharge was temperature-dependent and did not occur at 0 C. In the schizokinen-requiring strain B. megaterium SK11 similar release of (3)H-schizokinen occurred only at elevated concentrations of the double-labeled chelate; at lower chelate concentrations, (3)H-schizokinen remained cell-associated. Temperature-dependent uptake of deferri (iron-free) (3)H-schizokinen to levels equivalent to those incorporated from the chelate form was noted in strain SK11, but strain ATCC 19213 showed only temperature-independent binding of low concentrations of deferri (3)H-schizokinen. These results indicate an initial temperature-independent binding of the ferric hydroxamate which is followed rapidly by temperature-dependent transport of the chelate into the cell and an enzyme catalyzed separation of iron from the chelate. The resulting deferri hydroxamate is discharged from the cell only when a characteristic intracellular concentration of the hydroxamate is exceeded, which happens in the schizokinen-requiring strain only at elevated concentrations of the chelate. This strain also appears to draw the deferri hydroxamate into the cell by a temperature-dependent mechanism. The aerobactin-producing organism Aerobacter aerogenes 62-1 also demonstrated rapid initial uptake and temperature-dependent discharge of (3)H-aerobactin during iron transport from (3)H-aerobactin-(59)Fe(3+), suggesting a similar ferric hydroxamate transport system in this organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199517"} {"pmid": "4199518", "title": "Efficiency of energy conversion by aerobic glucose metabolism in Aphancapsa 6714.", "content": "Efficiency of energy conversion by aerobic glucose metabolism in Aphancapsa 6714. Efficiency of adenosine triphosphate (ATP) formation from glucose oxidation in Aphanocapsa 6714 was estimated by quantitative measurement of phosphorylated intermediary metabolites and glycogen (polyglucose) formed from (14)C-glucose. P/2e ratios based on oxygen uptake ranged from 2.62 to 3.08, whereas those based on (14)CO(2) evolution ranged from 1.66 to 1.72. The synthesis of glycogen, which is the dominant energy-consuming process in resting cells exposed to exogenous glucose, was almost totally inhibited under anaerobic conditions, and the cellular concentration of ATP decreased steadily. Thus, both net synthesis of ATP and the steady-state concentration of ATP are obligatorily linked to respiration in this heterotrophic unicellular blue-green alga.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199518"} {"pmid": "4199520", "title": "Cell-bound thiaminase I of Bacillus thiaminolyticus.", "content": "Cell-bound thiaminase I of Bacillus thiaminolyticus. The distribution of the extracellular enzyme, thiaminase I, was determined for logarithmically growing cultures of Bacillus thiaminolyticus. About 60% of the enzyme is associated with the cells throughout the growth cycle. The remainder of the enzyme is in the culture medium. The release of the cell-bound thiaminase I is examined under a variety of conditions. The rate and extent of release is dependent on the pH and the nature of the incubation solution. The release process appears to be relatively independent of de novo protein synthesis, energy derived from oxidative phosphorylation, or divalent metal ions. The absence of carbon or nitrogen sources has little effect on the release of the enzyme. Cell-bound thiaminase I probably is the immediate precursor for extracellular thiaminase I found in the culture medium. Washed cells continue to release thiaminase I at the expense of cell-bound enzyme. In addition, purified cell-bound thiaminase I is indistinguishable from purified extracellular thiaminase I by a number of physical and kinetic criteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199520"} {"pmid": "4199519", "title": "Kinetics of glucose incorporation by Aphanocapsa 6714.", "content": "Kinetics of glucose incorporation by Aphanocapsa 6714. Photoautotrophic metabolism of CO(2) was compared with glucose metabolism in the facultative unicellular blue-green alga, Aphanocapsa 6714. Glucose-fed cells incorporated more (14)C into phosphorylated sugar intermediates of the reductive and oxidative pentose phosphate cycles than autotrophic cells. The relative increases were: 140-fold in dark cells; 32-fold in dichlorophenylmethylurea (DCMU)-inhibited cells; and 16-fold in cells assumilating glucose during photosynthetic carbon reduction. On the other hand, incorporation of (14)C from glucose into 3-phosphoglycerate and the amino acid pools of glutamate and aspartate was reduced in dark cells. Rates of protein synthesis in dark and DCMU-inhibited cells were reduced 50 and 80% compared to photoautotrophic cells. In cells assimilating glucose during photosynthesis, rates of (14)C incorporation into the two amino acids and protein were the same as in photoautotrophic cells. Chase experiments, using an excess of (12)C-glucose and CO(2), revealed slow turnover of carbon in dark cells and intermediate turnover rates in DCMU-inhibited cells, when compared to cells assimilating glucose during photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199519"} {"pmid": "4199521", "title": "Reversible inactivation of thiaminase I of Bacillus thiaminolyticus by its primary substrate, thiamine.", "content": "Reversible inactivation of thiaminase I of Bacillus thiaminolyticus by its primary substrate, thiamine. Thiaminase I of Bacillus thiaminolyticus is reversibly inactivated when it is incubated with its primary substrate, thiamine, or with one of several structural analogues of thiamine in the absence of an acceptor base. The inactivation reaction is pH and temperature dependent and is stochiometric with respect to thiamine and thiaminase I concentrations. One molecule of thiamine is cleaved for each molecule of enzyme inactivated. Inactivation is prevented or reversed by sulfhydryl-reducing agents. Active or reactivated thiaminase I migrate as a single band in polyacrylamide electrophoresis gels. Inactive thiaminase I appears to migrate as two separate bands. Active, inactive, and reactivated thiaminase I are immunologically similar. A possible mechanism for the inactivation of thiaminase I by its substrate is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199521"} {"pmid": "4199522", "title": "Comprehensive rehabilitation of the patient with cancer. Five-year experience of a home-care unit.", "content": "Comprehensive rehabilitation of the patient with cancer. Five-year experience of a home-care unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199522"} {"pmid": "4199523", "title": "Precipitating antibody against pigeon antigens in sera of asymptomatic pigeon breeders.", "content": "Precipitating antibody against pigeon antigens in sera of asymptomatic pigeon breeders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199523"} {"pmid": "4199524", "title": "Characterization and significance of urinary fibrin degradation products.", "content": "Characterization and significance of urinary fibrin degradation products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199524"} {"pmid": "4199526", "title": "Prolonged survival after complete small bowel resection using intravenous alimentation at home.", "content": "Prolonged survival after complete small bowel resection using intravenous alimentation at home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199526"} {"pmid": "4199525", "title": "Hepatic drug metabolism and protein malnutrition.", "content": "Hepatic drug metabolism and protein malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199525"} {"pmid": "4199528", "title": "Co-trimaxazole therapy: place and prospects.", "content": "Co-trimaxazole therapy: place and prospects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199528"} {"pmid": "4199527", "title": "Sensitivity testing with trimethorpim-sulphamethoxazole.", "content": "Sensitivity testing with trimethorpim-sulphamethoxazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199527"} {"pmid": "4199529", "title": "Trimethoprim-sulphamethoxazole effect on folate metabolism.", "content": "Trimethoprim-sulphamethoxazole effect on folate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199529"} {"pmid": "4199530", "title": "Trimethoprim-sulphamethoxazole: long-term therapy and folate levels.", "content": "Trimethoprim-sulphamethoxazole: long-term therapy and folate levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199530"} {"pmid": "4199533", "title": "Inhibition by imidazole of the increase in intraocular pressure induced by topical prostaglandin E.", "content": "Inhibition by imidazole of the increase in intraocular pressure induced by topical prostaglandin E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199533"} {"pmid": "4199538", "title": "Serum growth hormone in diabetic coma.", "content": "Serum growth hormone in diabetic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199538"} {"pmid": "4199539", "title": "Failure of SC-19220 to affect prostaglandin E1 (PGR1) gastric antisecretory actions.", "content": "Failure of SC-19220 to affect prostaglandin E1 (PGR1) gastric antisecretory actions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199539"} {"pmid": "4199542", "title": "Thio-TEPA therapy to prevent postoperative pterygium occurrence and neovascularization.", "content": "Thio-TEPA therapy to prevent postoperative pterygium occurrence and neovascularization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199542"} {"pmid": "4199543", "title": "Pressure-dependency of the aqueous outflow.", "content": "Pressure-dependency of the aqueous outflow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199543"} {"pmid": "4199545", "title": "Angiologic assessment of the hemodynamic effects of sustained release nitroglycerin in patients with angina pectoris.", "content": "Angiologic assessment of the hemodynamic effects of sustained release nitroglycerin in patients with angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199545"} {"pmid": "4199549", "title": "Care of anesthetic equipment and other devices.", "content": "Care of anesthetic equipment and other devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199549"} {"pmid": "4199550", "title": "The isolation of erythrocyte membrane proteins in aqueous media.", "content": "The isolation of erythrocyte membrane proteins in aqueous media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199550"} {"pmid": "4199552", "title": "Interaction of thyroxine with rat adenohypophysial proteins in vitro.", "content": "Interaction of thyroxine with rat adenohypophysial proteins in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199552"} {"pmid": "4199553", "title": "Elimination of recessive lethals in model populations of Drosophila melanogaster.", "content": "Elimination of recessive lethals in model populations of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199553"} {"pmid": "4199554", "title": "Infectious DNA from coliphage T1. IV. The action of radicals induced by 60Co-gamma rays in the wet state.", "content": "Infectious DNA from coliphage T1. IV. The action of radicals induced by 60Co-gamma rays in the wet state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199554"} {"pmid": "4199556", "title": "Synthesis of IgG, IgA, IgM by chicken tissues: immunofluorescent and 14C amino acid incorporation studies.", "content": "Synthesis of IgG, IgA, IgM by chicken tissues: immunofluorescent and 14C amino acid incorporation studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199556"} {"pmid": "4199555", "title": "Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans.", "content": "Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199555"} {"pmid": "4199557", "title": "Immunoglobulins in the developing amphibian, Rana catesbeiana.", "content": "Immunoglobulins in the developing amphibian, Rana catesbeiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199557"} {"pmid": "4199558", "title": "Human immunoglobulin A: production of an Fc fragment by an enteric microbial proteolytic enzyme.", "content": "Human immunoglobulin A: production of an Fc fragment by an enteric microbial proteolytic enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199558"} {"pmid": "4199559", "title": "The role of thymus-derived lymphocytes in the in vitro activation of macrophages to kill Listeria monocytogenes.", "content": "The role of thymus-derived lymphocytes in the in vitro activation of macrophages to kill Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199559"} {"pmid": "4199561", "title": "Changing patterns of bacterial meningitis in Olmsted County, Minnesota, 1935-1970.", "content": "Changing patterns of bacterial meningitis in Olmsted County, Minnesota, 1935-1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199561"} {"pmid": "4199560", "title": "Antinucleolar antibodies in human sera.", "content": "Antinucleolar antibodies in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199560"} {"pmid": "4199562", "title": "Preliminary characterization of the heat-labile enterotoxin of Escherichia coli F11(P155).", "content": "Preliminary characterization of the heat-labile enterotoxin of Escherichia coli F11(P155).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199562"} {"pmid": "4199563", "title": "Rocky Mountain spotted fever: a comparative study of the active immunity induced by inactivated and viable pathogenic Rickettsia rickettsii.", "content": "Rocky Mountain spotted fever: a comparative study of the active immunity induced by inactivated and viable pathogenic Rickettsia rickettsii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199563"} {"pmid": "4199564", "title": "Electron microscope study of the structures of the Bacillus subtilis prophages, SPO2 and phi105.", "content": "Electron microscope study of the structures of the Bacillus subtilis prophages, SPO2 and phi105.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199564"} {"pmid": "4199565", "title": "Electron microscope mapping of the distribution of ribosomal genes of the Bacillus subtilis chromosome.", "content": "Electron microscope mapping of the distribution of ribosomal genes of the Bacillus subtilis chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199565"} {"pmid": "4199567", "title": "An electromechanical hypothesis for ciliary coordination in ciliated protozoa.", "content": "An electromechanical hypothesis for ciliary coordination in ciliated protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199567"} {"pmid": "4199571", "title": "Vitellogenesis induced by juvenile hormone in the female sterile mutant apterous-four in Drosophila melanogaster.", "content": "Vitellogenesis induced by juvenile hormone in the female sterile mutant apterous-four in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199571"} {"pmid": "4199570", "title": "Immunological studies of factor VIII in haemophilia and von Willebrand's disease.", "content": "Immunological studies of factor VIII in haemophilia and von Willebrand's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199570"} {"pmid": "4199572", "title": "Microbiological quality of Norwegian butter and margarine.", "content": "Microbiological quality of Norwegian butter and margarine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199572"} {"pmid": "4199574", "title": "Chronic thyroiditis in buffalo-strain rats ingesting 3'-methyl-4-dimethylaminoazobenzene or N-2-fluorenyldiacetamide.", "content": "Chronic thyroiditis in buffalo-strain rats ingesting 3'-methyl-4-dimethylaminoazobenzene or N-2-fluorenyldiacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199574"} {"pmid": "4199576", "title": "Purines and purine nucleoside antagonists.", "content": "Purines and purine nucleoside antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199576"} {"pmid": "4199577", "title": "Enzymes as immunosuppressants: basic considerations.", "content": "Enzymes as immunosuppressants: basic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199577"} {"pmid": "4199578", "title": "Diagnosis and management of infections associated with immunosuppression. New antibiotics of potential importance for immunosuppressed patients.", "content": "Diagnosis and management of infections associated with immunosuppression. New antibiotics of potential importance for immunosuppressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199578"} {"pmid": "4199579", "title": "Patient isolation units for cancer patients treated with chemical immunosuppressive agents.", "content": "Patient isolation units for cancer patients treated with chemical immunosuppressive agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199579"} {"pmid": "4199566", "title": "Scintillation cameras and multiprobe detectors--their advantages and disadvantages in brain perfusion measurements.", "content": "Scintillation cameras and multiprobe detectors--their advantages and disadvantages in brain perfusion measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199566"} {"pmid": "4199580", "title": "The in vivo activity of in vitro immunized mouse thymocytes. 3. Fate of in vitro immunized thymocytes.", "content": "The in vivo activity of in vitro immunized mouse thymocytes. 3. Fate of in vitro immunized thymocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199580"} {"pmid": "4199581", "title": "51Cr release microassays for histocompatibility antigens on normal and malignant cells.", "content": "51Cr release microassays for histocompatibility antigens on normal and malignant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199581"} {"pmid": "4199582", "title": "Immunochemical specificity of cytoplasmic inclusions induced by viruses in the potato Y group.", "content": "Immunochemical specificity of cytoplasmic inclusions induced by viruses in the potato Y group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199582"} {"pmid": "4199575", "title": "Prophylaxis of Rh-immunization with immunoglobulin anti-D.", "content": "Prophylaxis of Rh-immunization with immunoglobulin anti-D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199575"} {"pmid": "4199585", "title": "Serological cross-reactions between different Brucella species and Yersinia enterocolitica. Biological and chemical investigations of lipopolysaccharides from Brucella abortus and Yersinia enterocolitica type IX.", "content": "Serological cross-reactions between different Brucella species and Yersinia enterocolitica. Biological and chemical investigations of lipopolysaccharides from Brucella abortus and Yersinia enterocolitica type IX.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199585"} {"pmid": "4199584", "title": "Testosterone regulation of pigmentation in scrotal epidermis of the rat.", "content": "Testosterone regulation of pigmentation in scrotal epidermis of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199584"} {"pmid": "4199586", "title": "Cell division after inhibition of DNA and protein synthesis in Neisseria meningitidis. 1. Blockage of division in synchronized populations by hydroxyurea and chloramphenicol.", "content": "Cell division after inhibition of DNA and protein synthesis in Neisseria meningitidis. 1. Blockage of division in synchronized populations by hydroxyurea and chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199586"} {"pmid": "4199587", "title": "Cell division after inhibition of DNA and protein synthesis in Neisseria meningitidis. 2. Residual division and increase in absorbancy in exponential phase cultures after addition of hydroxyurea and chloramphenicol.", "content": "Cell division after inhibition of DNA and protein synthesis in Neisseria meningitidis. 2. Residual division and increase in absorbancy in exponential phase cultures after addition of hydroxyurea and chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199587"} {"pmid": "4199588", "title": "The occurrence of measles antigen precipitating antibodies in sera from patients with multiple sclerosis and their relatives.", "content": "The occurrence of measles antigen precipitating antibodies in sera from patients with multiple sclerosis and their relatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199588"} {"pmid": "4199589", "title": "Three new Escherichia coli O antigens O154, O155 and O156, and one new K antigen, K94.", "content": "Three new Escherichia coli O antigens O154, O155 and O156, and one new K antigen, K94.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199589"} {"pmid": "4199590", "title": "Epidemiological markers for Pseudomonas aeruginosa. 1. Serogrouping, pyocine typing--and their interrelations.", "content": "Epidemiological markers for Pseudomonas aeruginosa. 1. Serogrouping, pyocine typing--and their interrelations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199590"} {"pmid": "4199591", "title": "Epidemiological markers for Pseudomonas aeruginosa. 2. Relationship between bacteriophage susceptibility and serogroup or pyocine type.", "content": "Epidemiological markers for Pseudomonas aeruginosa. 2. Relationship between bacteriophage susceptibility and serogroup or pyocine type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199591"} {"pmid": "4199592", "title": "Epidemiological markers for Pseudomonas aeruginosa. 3. Comparison of bacteriophage typing, serogrouping, and pyocine typing on a heterogeneous clinical material.", "content": "Epidemiological markers for Pseudomonas aeruginosa. 3. Comparison of bacteriophage typing, serogrouping, and pyocine typing on a heterogeneous clinical material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199592"} {"pmid": "4199593", "title": "Incidence of Rh immunization following abortion: possible detection of lymphocyte priming to Rh antigen.", "content": "Incidence of Rh immunization following abortion: possible detection of lymphocyte priming to Rh antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199593"} {"pmid": "4199594", "title": "Community mental health services in Britain.", "content": "Community mental health services in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199594"} {"pmid": "4199595", "title": "Growth of bacteria and fungi in total parenteral nutrition solutions.", "content": "Growth of bacteria and fungi in total parenteral nutrition solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199595"} {"pmid": "4199599", "title": "Antitumor activities of bacterial leucine dehydrogenase and glutaminase A.", "content": "Antitumor activities of bacterial leucine dehydrogenase and glutaminase A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199599"} {"pmid": "4199601", "title": "Use of elemental diet during the adaptive stage of short gut syndrome.", "content": "Use of elemental diet during the adaptive stage of short gut syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199601"} {"pmid": "4199600", "title": "The use of reporter group circular dichroism in the study of conformational transitions in bovine serum albumin.", "content": "The use of reporter group circular dichroism in the study of conformational transitions in bovine serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199600"} {"pmid": "4199602", "title": "Amino acid adequacy of parenteral casein hydrolysate and oral cottage cheese in patients with gastrointestinal disease as measured by nitrogen balance and blood aminogram.", "content": "Amino acid adequacy of parenteral casein hydrolysate and oral cottage cheese in patients with gastrointestinal disease as measured by nitrogen balance and blood aminogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199602"} {"pmid": "4199603", "title": "The problem-oriented medical record in long-term institutional care.", "content": "The problem-oriented medical record in long-term institutional care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199603"} {"pmid": "4199604", "title": "Immunological studies of coagulation factor XIII.", "content": "Immunological studies of coagulation factor XIII. Human fibrin-stabilizing factor (Factor XIII) has been studied immunologically by the preparation of specific anti-Factor XIII antiserum in rabbits. On immunodiffusion it was found that normal plasma produced two precipitin lines. One of the precipitin lines was identical with that present in soluble platelet extract (the alpha-component), the other with that present in normal serum (beta-component). Plasma and serum of patients with congenital Factor XIII deficiency contained only the beta-component. By adsorption it was possible to prepare a second antiserum with solely anti-alpha-activity that did not react with the serum or plasma of XIII-deficient patients. Both antisera neutralized the clot-stabilizing activity of normal plasma. The action of thrombin on fibrinogen-free plasma or platelet extract abolished the immunoprecipitin alpha-line but did not reduce the capacity to neutralize antibody as measured by clot stabilization. It is concluded that the plasma Factor XIII molecule consists of two immunologically identifiable components, alpha and beta. The clot-stabilizing activity and thrombin-reactive site are situated on the alpha-component. Patients with congenital Factor XIII deficiency are devoid of immunologically identifiable or functional alpha-component but retain immunologically identifiable beta-component. It is this beta-component that accounts for the observed immunologically detectable Factor XIII in those patients devoid of clot-stabilizing activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199604"} {"pmid": "4199605", "title": "Acute changes in oxyhemoglobin affinity. Effects on oxygen transport and utilization.", "content": "Acute changes in oxyhemoglobin affinity. Effects on oxygen transport and utilization. It has been postulated that 2,3-diphosphoglycerate (DPG)-mediated changes in oxyhemoglobin affinity play an important role in oxygen delivery; however, the effect of an acute increase in affinity without changing red cell mass has not been systematically evaluated. This study was designed to measure changes in oxygen transport and oxygen consumption produced by an acute increase in oxyhemoglobin affinity caused by an autologous exchange transfusion using DPG-depleted stored blood. From each of 10 5-kg rhesus monkeys, 100 ml of blood was taken on the 1st and 3rd wk of the study and each stored in 25 ml of acid-citrate-dextrose storage solution. On the 5th wk, each animal underwent an exchange transfusion with 200 ml of its stored blood. Hemodynamic data were obtained before and 30 min after transfusion. The oxyhemoglobin dissociation curve shifted to the left (P(50) changed from 33.9 to 27.2 mm Hg), as mean red cell DPG decreased from 28.6 to 12.7 mumol/g of hemoglobin. No significant change was noted in pH, P(CO2), base deficit, arterial or venous percent saturation of hemoglobin, cardiac output, or oxygen consumption. However, a fall in mixed venous P(O2) from 35.3 to 27.9 mm Hg occurred.Thus, an acute shift of the oxyhemoglobin curve to the left was accompanied by a significant decrease in the mixed venous P(O2) without evidence of acidosis, decreased oxygen consumption, or a compensatory increase in cardiac output.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199605"} {"pmid": "4199606", "title": "A simple trauma model in the rat.", "content": "A simple trauma model in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199606"} {"pmid": "4199607", "title": "Exertional arrhythmia and nitgroglycerin.", "content": "Exertional arrhythmia and nitgroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199607"} {"pmid": "4199608", "title": "Malignant pleural disease. A radiotherapeutic approach to the problem.", "content": "Malignant pleural disease. A radiotherapeutic approach to the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199608"} {"pmid": "4199610", "title": "Immunological identification of human semen.", "content": "Immunological identification of human semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199610"} {"pmid": "4199611", "title": "Filters for intravenous alimentation.", "content": "Filters for intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199611"} {"pmid": "4199612", "title": "Specificity of precipitating antibodies in immunological identification of antihaemophilic factor.", "content": "Specificity of precipitating antibodies in immunological identification of antihaemophilic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199612"} {"pmid": "4199613", "title": "Tyrosinase activity in subcellular fractions of black and albino mice.", "content": "Tyrosinase activity in subcellular fractions of black and albino mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199613"} {"pmid": "4199614", "title": "Aspirin inhibition of in vitro osteolysis stimulated by parathyroid hormone and PGE1.", "content": "Aspirin inhibition of in vitro osteolysis stimulated by parathyroid hormone and PGE1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199614"} {"pmid": "4199615", "title": "Prostaglandin regulation of airway smooth muscle tone.", "content": "Prostaglandin regulation of airway smooth muscle tone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199615"} {"pmid": "4199616", "title": "An evaluation of five percent sulfamylon cream in control of experimental burn wound sepsis.", "content": "An evaluation of five percent sulfamylon cream in control of experimental burn wound sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199616"} {"pmid": "4199622", "title": "Regulation of erythropoiesis by androgens.", "content": "Regulation of erythropoiesis by androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199622"} {"pmid": "4199617", "title": "Ocular anomalies in malformation syndromes.", "content": "Ocular anomalies in malformation syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199617"} {"pmid": "4199621", "title": "Ketosis.", "content": "Ketosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199621"} {"pmid": "4199624", "title": "On the transferrin concentration in blood serum of growing calves and in bovine colostrum.", "content": "On the transferrin concentration in blood serum of growing calves and in bovine colostrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199624"} {"pmid": "4199625", "title": "The composition of bovine udder secretion during the first half of the dry period.", "content": "The composition of bovine udder secretion during the first half of the dry period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199625"} {"pmid": "4199627", "title": "Studies on the gestational changes in the buffalo uterus. I. The histo-morphological changes.", "content": "Studies on the gestational changes in the buffalo uterus. I. The histo-morphological changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199627"} {"pmid": "4199619", "title": "Recovery of the rod and cone cells after photic injury.", "content": "Recovery of the rod and cone cells after photic injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199619"} {"pmid": "4199628", "title": "Variations in thyroid status of the buffalo during the estrous cycle, pregnancy and in conditions of ovarian abnormalities.", "content": "Variations in thyroid status of the buffalo during the estrous cycle, pregnancy and in conditions of ovarian abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199628"} {"pmid": "4199620", "title": "Tuberculosis of the tongue.", "content": "Tuberculosis of the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199620"} {"pmid": "4199630", "title": "Congenital cerebellar ataxia in the gotland pony breed.", "content": "Congenital cerebellar ataxia in the gotland pony breed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199630"} {"pmid": "4199632", "title": "Comparative studies on glycerol 3-phosphate dehydrogenase in bees and wasps.", "content": "Comparative studies on glycerol 3-phosphate dehydrogenase in bees and wasps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199632"} {"pmid": "4199633", "title": "Purification and crystallization of three isoenzymes of malate dehydrogenase from Zea mays seed.", "content": "Purification and crystallization of three isoenzymes of malate dehydrogenase from Zea mays seed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199633"} {"pmid": "4199634", "title": "The synthesis of 3-nonaprenyl-4-hydroxybenzoate in rat liver mitochondria: the effect of Ca2 , Mg2+, chelators, and bacitracin on the activity of p-hydroxybenzoate-polyprenyl transferase.", "content": "The synthesis of 3-nonaprenyl-4-hydroxybenzoate in rat liver mitochondria: the effect of Ca2 , Mg2+, chelators, and bacitracin on the activity of p-hydroxybenzoate-polyprenyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199634"} {"pmid": "4199635", "title": "Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. 3. Biosynthesis of carbonic anhydrases in bone marrow erythroid cells and peripheral blood reticulocytes of Macaca nemestria.", "content": "Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. 3. Biosynthesis of carbonic anhydrases in bone marrow erythroid cells and peripheral blood reticulocytes of Macaca nemestria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199635"} {"pmid": "4199618", "title": "Wide-angle holography of the eye.", "content": "Wide-angle holography of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199618"} {"pmid": "4199636", "title": "The pancreatic -cell recognition of insulin secretagogues. VII. Binding and permeation of chloromercuribenzene-p-sulphonic acid in the plasma membrane of pancreatic -cells.", "content": "The pancreatic -cell recognition of insulin secretagogues. VII. Binding and permeation of chloromercuribenzene-p-sulphonic acid in the plasma membrane of pancreatic -cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199636"} {"pmid": "4199637", "title": "The Donnan effect in tobacco mosaic virus and its components.", "content": "The Donnan effect in tobacco mosaic virus and its components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199637"} {"pmid": "4199638", "title": "Preparation and partial fractionation of nonhistone chromosomal proteins from human diploid fibroblasts.", "content": "Preparation and partial fractionation of nonhistone chromosomal proteins from human diploid fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199638"} {"pmid": "4199643", "title": "Effects of long-term adjuvant chemotherapy with cyclophosphamide (NSC-26271) for radically resected bronchogenic carcinoma.", "content": "Effects of long-term adjuvant chemotherapy with cyclophosphamide (NSC-26271) for radically resected bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199643"} {"pmid": "4199642", "title": "Shock, cerebral hypoxia, and pulmonary vascular control: the centrineurogenic etiology of the respiratory distress syndrome.", "content": "Shock, cerebral hypoxia, and pulmonary vascular control: the centrineurogenic etiology of the respiratory distress syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199642"} {"pmid": "4199644", "title": "Results of combination treatment of lung cancer patients: surgery plus radiotherapy and surgery plus chemotherapy.", "content": "Results of combination treatment of lung cancer patients: surgery plus radiotherapy and surgery plus chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199644"} {"pmid": "4199645", "title": "Chemotherapy for lung cancer at the Institute of Experimental and Clinical Oncology, Academy of Medical Sciences, USSR.", "content": "Chemotherapy for lung cancer at the Institute of Experimental and Clinical Oncology, Academy of Medical Sciences, USSR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199645"} {"pmid": "4199646", "title": "Trauma as a cause of epilepsy in childhood.", "content": "Trauma as a cause of epilepsy in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199646"} {"pmid": "4199647", "title": "The localization of DNA ligase in the chromatin of animal cells.", "content": "The localization of DNA ligase in the chromatin of animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199647"} {"pmid": "4199648", "title": "Test for missynthesis of lactate dehydrogenase in aging mice by use of a monospecific antibody.", "content": "Test for missynthesis of lactate dehydrogenase in aging mice by use of a monospecific antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199648"} {"pmid": "4199649", "title": "Age-associated changes in viability genetic loads of Drosophila melanogaster.", "content": "Age-associated changes in viability genetic loads of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199649"} {"pmid": "4199650", "title": "Heat tolerance changes with age in normal and irradiated Drosophila melanogaster.", "content": "Heat tolerance changes with age in normal and irradiated Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199650"} {"pmid": "4199651", "title": "Testing of rifampicin on possible genetic effects on Drosophila melanogaster and human leukocyte chromosomes in vitro.", "content": "Testing of rifampicin on possible genetic effects on Drosophila melanogaster and human leukocyte chromosomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199651"} {"pmid": "4199652", "title": "A method for freezing living ovaries of Drosophila melanogaster larvae and its application to the storage of mutant stocks.", "content": "A method for freezing living ovaries of Drosophila melanogaster larvae and its application to the storage of mutant stocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199652"} {"pmid": "4199653", "title": "Distribution of 5S RNA in the liver of the South American rattlesnake, Crotalus durissus terrificus.", "content": "Distribution of 5S RNA in the liver of the South American rattlesnake, Crotalus durissus terrificus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199653"} {"pmid": "4199654", "title": "Effects of nicotine and arousal on the monkey electroencephalogram.", "content": "Effects of nicotine and arousal on the monkey electroencephalogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199654"} {"pmid": "4199656", "title": "Separation of peptides according to charge by gel filtration in the presence of ionized detergents.", "content": "Separation of peptides according to charge by gel filtration in the presence of ionized detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199656"} {"pmid": "4199657", "title": "Nonhistone chromatin protein phosphorylation during azo-dye carcinogenesis.", "content": "Nonhistone chromatin protein phosphorylation during azo-dye carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199657"} {"pmid": "4199659", "title": "Complementary chromatic adaptation in a filamentous blue-green alga.", "content": "Complementary chromatic adaptation in a filamentous blue-green alga. Fluorescent and red light environments generate greatly different patterns of pigmentation and morphology in Fremyella diplosiphon. Most strikingly, red-illuminated cultures contain no measurable C-phycoerythrin and have a mean filament length about 10 times shorter than fluorescent-illuminated cultures. C-phycoerythrin behaves as a photoinducible constituent of this alga. Spectrophotometric and immunochemical procedures were devised so that C-phycoerythrin metabolism could be studied quantitatively with [(14)C]-phenylalanine pulse-chased cultures. Transfer of red-illuminated cultures to fluorescent light initiates C-phycoerythrin production by essentially de novo synthesis. C-phycoerythrin is not degraded to any significant extent in cultures continuously illuminated with fluorescent light. Transfer of fluorescent-illuminated cultures to red light causes an abrupt cessation of C-phycoerythrin synthesis. The C-phycoerythrin content of cultures adapting to red light decreases and subsequently becomes constant. Loss of C-phycoerythrin is not brought about by metabolic degradation, but rather by a decrease in mean filament length which is effected by transcellular breakage. In this experimental system, light influences intracellular C-phycoerythrin levels by regulating the rate of synthesis of the chromoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199659"} {"pmid": "4199660", "title": "Sedimentation velocity characterisation of the cell cycle of granulocytic progenitor cells in monkey hemopoietic tissue.", "content": "Sedimentation velocity characterisation of the cell cycle of granulocytic progenitor cells in monkey hemopoietic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199660"} {"pmid": "4199658", "title": "Fracture faces of zonulae occludentes from \"tight\" and \"leaky\" epithelia.", "content": "Fracture faces of zonulae occludentes from \"tight\" and \"leaky\" epithelia. Epithelia vary with respect to transepithelial permeability. In those that are considered \"leaky\", a large fraction of the passive transepithelial flux appears to follow the paracellular route, passing across the zonulae occludentes and moving down the intercellular clefts. In \"tight\" epithelia, the resistance of the paracellular pathway to passive flux is greatly increased. To see whether differences in the morphology of the zonula occludens could contribute to this variability in leakiness among epithelia, replicas of zonulae occludentes in freeze-fractured material from a variety of tight and leaky epithelia were examined. The junctions appear as a branching and anastomosing network of strands or grooves on the A and B membrane fracture faces, respectively. It was found that the zonula occludens from a \"very leaky\" epithelium, the proximal convoluted tubule of the mouse kidney, is extremely shallow in the apical-basal direction, consisting in most places of only one junctional strand. In contrast, the \"very tight\" frog urinary bladder exhibits a zonula occludens that is relatively deep (>0.5 microm) in the apical-basal direction, and consists of five or more interconnected junctional strands interposed between luminal and lateral membrane surfaces. Epithelia of intermediate permeabilities exhibited junctions with intermediate or variable morphology. Toad urinary bladder, mouse stomach, jejunum, and distal tubule, rabbit gallbladder, and Necturus kidney and gallbladder were also examined, and the morphological data from these epithelia were compared to physiological data from the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199658"} {"pmid": "4199661", "title": "Surrogate rehabilitation of monkeys reared in total social isolation.", "content": "Surrogate rehabilitation of monkeys reared in total social isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199661"} {"pmid": "4199662", "title": "Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus.", "content": "Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199662"} {"pmid": "4199663", "title": "Adenovirus DNA. IV. Topology of adenovirus genomes.", "content": "Adenovirus DNA. IV. Topology of adenovirus genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199663"} {"pmid": "4199665", "title": "Further observation on the difference between Tyzzer's organisms from mice and those from rats.", "content": "Further observation on the difference between Tyzzer's organisms from mice and those from rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199665"} {"pmid": "4199666", "title": "Immunologic reactions of filaria-free beagle sera to Dirofilaria antigen.", "content": "Immunologic reactions of filaria-free beagle sera to Dirofilaria antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199666"} {"pmid": "4199668", "title": "Influence of fungicides on mycotoxin production by Alternaria mali.", "content": "Influence of fungicides on mycotoxin production by Alternaria mali.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199668"} {"pmid": "4199669", "title": "Mycoflora in cystic fibrosis: some ecologic aspects of Pseudomonas aeruginosa and Candida albicans.", "content": "Mycoflora in cystic fibrosis: some ecologic aspects of Pseudomonas aeruginosa and Candida albicans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199669"} {"pmid": "4199671", "title": "Preparation and specificity of antibodies to 15-keto-prostaglandin F2alpha.", "content": "Preparation and specificity of antibodies to 15-keto-prostaglandin F2alpha.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199671"} {"pmid": "4199672", "title": "Inhibition of abortion and fetal death produced by endotoxin or prostaglandin F2alpha.", "content": "Inhibition of abortion and fetal death produced by endotoxin or prostaglandin F2alpha.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199672"} {"pmid": "4199673", "title": "Possible mode of action of prostaglandins. V. Differential effects of prostaglandin F2 before and after the establishment of placental physiology in pregnant rats.", "content": "Possible mode of action of prostaglandins. V. Differential effects of prostaglandin F2 before and after the establishment of placental physiology in pregnant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199673"} {"pmid": "4199674", "title": "Absorption of prostaglandin E2 and uterine sensitivity of the non-pregnant and pregnant monkey in vivo.", "content": "Absorption of prostaglandin E2 and uterine sensitivity of the non-pregnant and pregnant monkey in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199674"} {"pmid": "4199675", "title": "Release of prostaglandins by the I.U.C.D.", "content": "Release of prostaglandins by the I.U.C.D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199675"} {"pmid": "4199676", "title": "Levels of 13,14-dihydro-15-keto-PGF in biological fluids as measured by radioimmunoassay.", "content": "Levels of 13,14-dihydro-15-keto-PGF in biological fluids as measured by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199676"} {"pmid": "4199677", "title": "Effect of intraventricularly administered prostaglandin E1 on the electrical activity of cerebral cortex and behavior in the unanesthetized monkey.", "content": "Effect of intraventricularly administered prostaglandin E1 on the electrical activity of cerebral cortex and behavior in the unanesthetized monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199677"} {"pmid": "4199678", "title": "Effect of polyphloretin phosphate and 7-oxa-13-prostynoic acid on the vasoactive actions of prostaglandin E2 and 5-hydroxytryptamine on isolated human umbilical arteries.", "content": "Effect of polyphloretin phosphate and 7-oxa-13-prostynoic acid on the vasoactive actions of prostaglandin E2 and 5-hydroxytryptamine on isolated human umbilical arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199678"} {"pmid": "4199680", "title": "Effect of aspirin upon male mouse fertility.", "content": "Effect of aspirin upon male mouse fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199680"} {"pmid": "4199679", "title": "Prostaglandin and eye.", "content": "Prostaglandin and eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199679"} {"pmid": "4199682", "title": "Substrate non-specificity of Streptococcus faecalis azoreductase.", "content": "Substrate non-specificity of Streptococcus faecalis azoreductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199682"} {"pmid": "4199683", "title": "The metabolism of 3-((5-methyl-5H-as-triazino(5,6-b)-indol-3-yl)amino)-1-propanol (SK&F 21687). A Potent antiviral.", "content": "The metabolism of 3-((5-methyl-5H-as-triazino(5,6-b)-indol-3-yl)amino)-1-propanol (SK&F 21687). A Potent antiviral.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199683"} {"pmid": "4199684", "title": "The effect of cyclophosphamide (endoxan) on histoenzymatic reactions in the liver. II. Studies on liver regeneration during cyclophosphamide administration.", "content": "The effect of cyclophosphamide (endoxan) on histoenzymatic reactions in the liver. II. Studies on liver regeneration during cyclophosphamide administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199684"} {"pmid": "4199685", "title": "Polarographic investigation on Pb++ trapping by subcellular fractions of rat liver.", "content": "Polarographic investigation on Pb++ trapping by subcellular fractions of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199685"} {"pmid": "4199686", "title": "A histochemical study of few enzymes in the neoplastic liver of Corvus spledens (Vieillot).", "content": "A histochemical study of few enzymes in the neoplastic liver of Corvus spledens (Vieillot).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199686"} {"pmid": "4199687", "title": "A histochemical study on the dihydrofolate reductase activity in leukemia.", "content": "A histochemical study on the dihydrofolate reductase activity in leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199687"} {"pmid": "4199690", "title": "Histochemical analysis of the neurosecretory product in fishes.", "content": "Histochemical analysis of the neurosecretory product in fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199690"} {"pmid": "4199691", "title": "Mucopolysaccharide histochemistry of Musca domestica. VI. The structure and development of chitin.", "content": "Mucopolysaccharide histochemistry of Musca domestica. VI. The structure and development of chitin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199691"} {"pmid": "4199693", "title": "Sequential staining for the correct histochemical localization of lactic dehydrogenase activity in formaldehyde-fixed frozen sections of a mixed muscle.", "content": "Sequential staining for the correct histochemical localization of lactic dehydrogenase activity in formaldehyde-fixed frozen sections of a mixed muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199693"} {"pmid": "4199698", "title": "Serum complement in normal pregnancy and pre-eclampsia.", "content": "Serum complement in normal pregnancy and pre-eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199698"} {"pmid": "4199697", "title": "Comparison of Bacillus thuringiensis with other bacillus species based on enzymoserological examinations of their proteolytic enzymes.", "content": "Comparison of Bacillus thuringiensis with other bacillus species based on enzymoserological examinations of their proteolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199697"} {"pmid": "4199699", "title": "Reservoir hosts of cutaneous leishmaniasis among Panamanian forest mammals.", "content": "Reservoir hosts of cutaneous leishmaniasis among Panamanian forest mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199699"} {"pmid": "4199700", "title": "Cerebral filariasis in Rhodesia--a zoonotic infection?", "content": "Cerebral filariasis in Rhodesia--a zoonotic infection?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199700"} {"pmid": "4199701", "title": "Effects of new laser systems on the skin.", "content": "Effects of new laser systems on the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199701"} {"pmid": "4199702", "title": "Ultrastructure of a pilar tumor.", "content": "Ultrastructure of a pilar tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199702"} {"pmid": "4199703", "title": "Kurotori virus: a virus newly isolated from Anopheles sinensis and pathogenic to mice. I. Isolation and properties.", "content": "Kurotori virus: a virus newly isolated from Anopheles sinensis and pathogenic to mice. I. Isolation and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199703"} {"pmid": "4199704", "title": "Effects of chelating agents on the initial interaction of phytohemagglutinin with lymphocytes and the subsequent stimulation of amino acid uptake.", "content": "Effects of chelating agents on the initial interaction of phytohemagglutinin with lymphocytes and the subsequent stimulation of amino acid uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199704"} {"pmid": "4199705", "title": "Maleyl-alpha-lactalbumin as lactose synthetase specifier protein.", "content": "Maleyl-alpha-lactalbumin as lactose synthetase specifier protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199705"} {"pmid": "4199706", "title": "Studies on the cell surface maltase of the rabbit renal cortex.", "content": "Studies on the cell surface maltase of the rabbit renal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199706"} {"pmid": "4199707", "title": "Inhibition of lectin agglutinability by fixation of the cell surface membrane.", "content": "Inhibition of lectin agglutinability by fixation of the cell surface membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199707"} {"pmid": "4199708", "title": "Airways narrowing in exercise in normal subjects and the effect of disodium cromoglycate.", "content": "Airways narrowing in exercise in normal subjects and the effect of disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199708"} {"pmid": "4199709", "title": "Tuberculosis of the male urethra.", "content": "Tuberculosis of the male urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199709"} {"pmid": "4199712", "title": "Sub-units of N-acetylglucosaminidases.", "content": "Sub-units of N-acetylglucosaminidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199712"} {"pmid": "4199713", "title": "Phospholipase C (Bacillus cereus) acts only at the inner surface of the erythrocyte membrane.", "content": "Phospholipase C (Bacillus cereus) acts only at the inner surface of the erythrocyte membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199713"} {"pmid": "4199714", "title": "Consequences of smallpox vaccination in leprosy patients.", "content": "Consequences of smallpox vaccination in leprosy patients. This study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. Results obtained with intradermal inoculations indicated that the patients with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy. Major vaccinial reactions were observed more often in patients with lepromatous leprosy than in the controls or patients with tuberculoid leprosy. Furthermore in a patient with lepromatous leprosy, vaccinia necrosum also developed. The smallpox vaccination with live virus also appeared as a provocative factor for the precipitation of lepra reaction in the lepromatous leprosy cases. After 3 weeks of vaccination, the frequency of the specific humoral antibody response was the same in the tuberculoid patients and controls while it was higher in the cases with lepromatous leprosy. The prevaccination titer of total hemagglutination inhibition antibody was significantly higher in the lepromatous leprosy cases. However, the postvaccinial, humoral antibody response of the lepromatous patients was of the same magnitude as that observed in the normal individuals, and it was mainly due to a 2-mercaptoethanol-resistant antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199714"} {"pmid": "4199716", "title": "Relative immunogenicity of streptomycin-sensitive and -resistant strains of BCG.", "content": "Relative immunogenicity of streptomycin-sensitive and -resistant strains of BCG. Normal, specific pathogen-free mice were vaccinated intravenously with increasing amounts of a streptomycin-resistant variety of BCG Tice (BCG SM(R)). The behavior of BCG SM(R) in the lungs, liver, and spleen was followed quantitatively for up to 50 days. One or two intravenous doses of 10(6) viable organisms were steadily eliminated from the tissues without producing detectable tuberculin sensitivity or raising resistance to a subsequent challenge with Mycobacterium tuberculosis strain Erdman. But mice receiving six weekly injections of 10(6) viable BCG SM(R) or a single injection of 10(6) BCG SM(R) by the intravenous route did develop effective levels of antituberculous resistance. Heat inactivation of the BCG SM(R) inoculum removed the organism's protective activity which could, however, be restored by incorporation of the organisms into Freund adjuvant. The ability of living BCG SM(R) to induce an effective antituberculous resistance when introduced into the tissues in an appropriate manner is discussed in terms of the mechanism of antituberculous immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199716"} {"pmid": "4199715", "title": "Association of group B coxsackie viruses with cases of pericarditis, myocarditis, or pleurodynia by demonstration of immunoglobulin M antibody.", "content": "Association of group B coxsackie viruses with cases of pericarditis, myocarditis, or pleurodynia by demonstration of immunoglobulin M antibody. Tests for immunoglobulin M (IgM) antibody to group B coxsackieviruses were performed on sera from 259 patients with a clinical diagnosis of pericarditis, myocarditis, or pleurodynia on whom there were no definitive serological or virus isolation findings to establish a viral etiology, and on 259 \"control\" patients with clinical diagnoses of viral or mycoplasmal pneumonia or pneumonitis. IgM antibodies to coxsackievirus types B1, B3, B4, B5, and B6 were detected by a micro-immunodiffusion technique, and antibodies to virus type B2 were detected by reduction of neutralizing antibodies with ethanethiol. Of the patients with pericarditis, myocarditis, or pleurodynia, 27% (70) had IgM antibody to group B coxsackieviruses, as compared with 8% in the control group. On retrospective review of the clinical diagnosis, some of the patients in the control group with IgM antibody were found to have had additional clinical findings which could be attributed to a coxsackievirus infection. Coxsackievirus IgM antibody was demonstrable in 30% of 113 patients in the study group for whom virus isolation had been attempted with negative results. The presence of coxsackievirus IgM is discussed in relation to the time of serum collection, age of the patients, and month of onset of illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199715"} {"pmid": "4199717", "title": "Antimycobacterial effect of lysates prepared from immunologically activated macrophages.", "content": "Antimycobacterial effect of lysates prepared from immunologically activated macrophages. Lysates or heptane extracts of peritoneal (P) and alveolar (A) normal macrophages (N-M), immune macrophages (I-M), and immune-activated macrophages (IA-M) were examined for antimycobacterial activity by the agar-plate diffusion test. This test has been found suitable to reveal the antibacterial activity in 3-day incubated, but not in freshly prepared, lysates. Results showed that materials of IA-AM or I-AM and of IA-PM exerted antimycobacterial effects, whereas materials of N-PM, I-PM, and of N-AM were usually inactive. Antimycobacterial activity of lysates of AM was stronger than that of PM. The formation of antibacterial factors during an incubation of M lysates, the solubility of the factors in heptane, and various other characteristics suggested that the antimycobacterial effect was caused by the formation of toxic levels of non-esterified fatty acids. M lysates exerted equal activities against BCG, H(37)Ra, and H(37)Rv strains of tubercle bacilli. The presence of antimycobacterial activity in lysates prepared from IA-M of either BCG- or BCG-sensitized animals indicated that the potential to generate antimycobacterial activity is associated with the state of delayed hypersensitivity and the state of activation of M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199717"} {"pmid": "4199710", "title": "Pharmacokinetic studies on minocycline in man.", "content": "Pharmacokinetic studies on minocycline in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199710"} {"pmid": "4199718", "title": "Ribosomal vaccines. II. Specificity of the immune response to ribosomal ribonucleic acid and protein isolated from Salmonella typhimurium.", "content": "Ribosomal vaccines. II. Specificity of the immune response to ribosomal ribonucleic acid and protein isolated from Salmonella typhimurium. Ribosomal proteins isolated from Salmonella typhimurium were effective in inducing immunity in mice. This immunity was specific since animals immunized with ribosomal proteins from S. typhimurium were not protected against challenge with S. cholerae-suis or S. enteritidis. Immunity was evident as early as 5 days after immunization. Ribosomal ribonucleic acid (RNA) failed to provide any effective immunity in mice. Polyinosinic acid: polycytidylic acid (poly I: C) induced a rapid, short-lived immunity to all three Salmonella species. In contrast, ribosomal RNA failed to elicit any rapid nonspecific response to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199718"} {"pmid": "4199719", "title": "Measurement of antibody-reactive toxin antigen during experimental staphylococcal B enterotoxemia.", "content": "Measurement of antibody-reactive toxin antigen during experimental staphylococcal B enterotoxemia. Staphylococcal enterotoxin B (SEB) injected intravenously is rapidly cleared from the circulation and deposited in tissues. Type-specific antiserum administered after toxin has left the circulation can influence the course of enterotoxemia, and this observation suggests that toxin antigens may either be returned to the circulation or reside on cell surfaces readily available to antibody. If SEB toxin or its fragments regain access to the extracellular space, they might react with circulating antibody and be detected and quantitated by the reduction in antibody titer. Accordingly, 1 h after toxin or saline injection, animals were given type-specific enterotoxin B antiserum, and the difference in titers between the animals was used to compute the amount of enterotoxin immediately available to antibody. Further, by measuring differences in titers over a 48-h period, an estimate was made of the amount of SEB antigen that gained access to antibody. The data indicate that rats, which are relatively resistant to the lethal effects of enterotoxin, clear toxin from the circulation promptly and that very little toxin reenters the circulation. Monkeys, who are highly susceptible to SEB, also clear toxin promptly. However, in contrasts to rats, monkeys have greater quantities of SEB immediately available to antibody and in addition return significant quantities of toxin antigens to the extracellular space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199719"} {"pmid": "4199720", "title": "Toxinogeny in Corynebacterium diphtheriae after loss of catalase, cystinase, or deoxyribonuclease activity.", "content": "Toxinogeny in Corynebacterium diphtheriae after loss of catalase, cystinase, or deoxyribonuclease activity. The relationship of catalase, cystinase, and deoxyribonuclease activity to toxinogeny in Corynebacterium diphtheriae was examined. Mutants deficient in each activity were isolated after mutagenization of strain C4 with nitrosoguanidine. All mutants were converted to toxinogeny after lysogenization with beta-converting phage, thus establishing that there is no absolute link between toxin production and these enzymatic activities. No differences were observed in the rate of lysogenization of the mutants by beta-converting phage over that of the parental strain. However, the data suggest that catalase mutants lysogenic for beta phage are generally induced at a higher rate than the parental strain after irradiation with ultraviolet light. Cystinase mutants vary widely in their rate of induction whereas the deoxyribonuclease mutants are similar to the parental strain. The relationship of these results to the production of toxinogenic strains is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199720"} {"pmid": "4199722", "title": "Origin and development of kinetosomes in Oxytricha fallax.", "content": "Origin and development of kinetosomes in Oxytricha fallax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199722"} {"pmid": "4199721", "title": "Serology of Streptococcus sanguis: localization of antigens with unlabeled antisera.", "content": "Serology of Streptococcus sanguis: localization of antigens with unlabeled antisera. A new technique for the electron microscope localization of bacterial surface antigens, using unlabeled antisera, has been developed. This technique, called the \"immuno-coating reaction\" was applied to serological studies of Streptococcus sanguis, using antisera which had been shown to be specific for this species by gel diffusion analysis. The results of the immuno-coating reaction confirmed the specificity of the antisera for S. sanguis. In addition, the data indicate that some of the antigens responsible for the reaction were proteins which formed filamentous processes on the surface of the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199721"} {"pmid": "4199723", "title": "The ultrastructural effects of excess maternal vitamin A on the primitive streak stage rat embryo.", "content": "The ultrastructural effects of excess maternal vitamin A on the primitive streak stage rat embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199723"} {"pmid": "4199724", "title": "New sensitive assay for phosphatidylserine decarboxylase based on the detection of CO2 from nonradiolabeled phosphatidylserine.", "content": "New sensitive assay for phosphatidylserine decarboxylase based on the detection of CO2 from nonradiolabeled phosphatidylserine. A new rapid assay for phosphatidylserine decarboxylase, which is sensitive in the nanomolar range, is described. Synthesis of radiolabeled phosphatidylserine for use as a substrate is not required, since the assay, unlike previous ones, is based on the detection of CO(2) liberated from unlabeled phosphatidylserine. The assay employs a gas chromatographic procedure for the analysis of methane formed by catalytic conversion of the CO(2) produced as a product of the enzymatic reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199724"} {"pmid": "4199725", "title": "Immunology of the gastrointestinal tract. I.", "content": "Immunology of the gastrointestinal tract. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199725"} {"pmid": "4199726", "title": "A fatal x-linked recessive reticuloendothelial syndrome with hyperglobulinemia. X-linked recessive reticuloendotheliosis.", "content": "A fatal x-linked recessive reticuloendothelial syndrome with hyperglobulinemia. X-linked recessive reticuloendotheliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199726"} {"pmid": "4199727", "title": "Disseminated intravascular coagulation in a newborn infant with Listeria sepsis.", "content": "Disseminated intravascular coagulation in a newborn infant with Listeria sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199727"} {"pmid": "4199728", "title": "Economics and medicos.", "content": "Economics and medicos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199728"} {"pmid": "4199729", "title": "Radioassay and the thyroid gland.", "content": "Radioassay and the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199729"} {"pmid": "4199730", "title": "Detection of virus antigens: hepatitis B antigen.", "content": "Detection of virus antigens: hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199730"} {"pmid": "4199731", "title": "The physiology of growth hormone regulation: pre- and postimmunoassay eras.", "content": "The physiology of growth hormone regulation: pre- and postimmunoassay eras.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199731"} {"pmid": "4199732", "title": "Depressive disorders: toward a unified hypothesis.", "content": "Depressive disorders: toward a unified hypothesis. Our scientific understanding of psychiatric syndromes, including the phenomena of depression, has been hampered because of: (i) the use of metapsychological concepts that are difficult to test; (ii) methodological and linguistic barriers that prevent communication among psychoanalysts, behaviorists, experimental psychologists, and psychiatrists; and (iii) the reluctance of psychiatrists to accept animal models as possible approximations of certain aspects of human psychopathology. We have attempted to demonstrate that the animal models simulate some of the central features of clinical depression (for example, helplessness and object loss), thereby allowing one to rigorously investigate them from developmental, behavioral, and biochemical perspectives. The object loss model, as a concrete version of a metapsychological-psychoanalytic concept, has enabled primatologists to study the disruption of an attachment bond. The behavioral model accommodates this concept to a broader generalization: loss of reinforcement or loss of control over reinforcement. We have reviewed the evidence that these processes involve the diencephalic centers of reward or reinforcement, thereby permitting integration of the psychoanalytical and behavioral formulations with the biochemical hypotheses. Also, we have presented data strongly suggesting that the breaking of an attachment bond in the primate represents significant loss of reinforcement that induces helplessness and disrupts motivated behavior. Finally, we have argued that the depressive syndrome could be caused by interactions of genetic, chemical, developmental, and interpersonal factors, all of which impinge on the diencephalic centers of reinforcement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199732"} {"pmid": "4199733", "title": "Experimental subacute spongiform virus encephalopathies in primates and other laboratory animals.", "content": "Experimental subacute spongiform virus encephalopathies in primates and other laboratory animals. The host range of subacute spongiform virus encephalopathies is described. The asymptomatic incubation period and the duration of the illnesses in various species of animal hosts is discussed along with information on additional species of Old World and New World monkeys and the domestic cat, which have been shown to be susceptible to subacute spongiform virus encephalopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199733"} {"pmid": "4199735", "title": "Instrumental conditioning of large-magnitude, daily, 12-hour blood pressure elevations in the baboon.", "content": "Instrumental conditioning of large-magnitude, daily, 12-hour blood pressure elevations in the baboon. Blood pressure and heart rate were monitored continuously in four baboons during extended exposure to a daily 12-hour conditioning procedure providing food and shock-avoidance as contingent consequences of prespecified increases in diastolic blood pressure. Sustained and significant increases (30 to 40 mm-Hg) in both systolic and diastolic blood pressure were maintained throughout the daily 12-hour conditioning sessions, accompanied by elevated heart rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199735"} {"pmid": "4199734", "title": "Induction of an enzyme in genetically deficient rats after grafting of normal liver.", "content": "Induction of an enzyme in genetically deficient rats after grafting of normal liver. Tissue from normal rat livers was grafted onto the livers of rats that were genetically deficient in bilirubin uridine diphosphate glucuronyltransferase activity. Twelve weeks after the grafting operation, the liver of the recipient rats had bilirubin uridine diphosphate glucuronyltransferase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199734"} {"pmid": "4199736", "title": "Controlled biliary drainage for large injuries of the liver.", "content": "Controlled biliary drainage for large injuries of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199736"} {"pmid": "4199737", "title": "Functional and morphologic changes after lung allografting in baboons.", "content": "Functional and morphologic changes after lung allografting in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199737"} {"pmid": "4199739", "title": "Adult versus infant brain damage: behavioral and electrophysiological effects of striatectomy in adult and neonatal rabbits.", "content": "Adult versus infant brain damage: behavioral and electrophysiological effects of striatectomy in adult and neonatal rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199739"} {"pmid": "4199741", "title": "Structure and function of natural proteinase inhibitors.", "content": "Structure and function of natural proteinase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199741"} {"pmid": "4199743", "title": "Immunological study of carcinoembryonic antigen (CEA) and a related glycoprotein.", "content": "Immunological study of carcinoembryonic antigen (CEA) and a related glycoprotein. A comparison has been made of the immunological properties of CEA (carcinoembryonic antigen) and another perchloric acid-soluble macromolecule which occurs in colonic and certain other carcinomata and which is here termed CEX. By using a variety of antisera it was shown that the two substances share common antigenic groups as well as having characteristic ones of their own. These latter groups have enabled the preparation of (a) antisera which give a gel diffusion line only with CEA and (b) and antiserum which gives a line only with CEX. No immunological difference could be found between CEX and the NGP of Mach or the NCA of von Kleist and Burtin. CEX was found in foetal gut, in plasma and associated with CEA in virtually all the tissues and fluids in which the latter occurs; the two appear to go hand-in-hand and no proof was found that CEX is either less or more cancer specific than CEA-it is merely found in greater quantity; neither substance showed absolute cancer specificity. The usefulness of a radioimmunoassay for CEX is discussed, and also the possibility of interference by CEX in the radioimmunoassay for CEA. Evidence of two molecular species of CEA has been found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199743"} {"pmid": "4199745", "title": "Significance of Pseudomonas aeruginosa in sputum.", "content": "Significance of Pseudomonas aeruginosa in sputum. Pseudomonas aeruginosa was isolated from the sputum of 63 patients. In 34 the organism was a commensal, in 14 it was causing chronic suppuration, and in 10 had interfered with antibiotics directed against other organisms and was thus indirectly pathogenic. In five patients, all of whom died, the organism could have been acting as an acute pathogen. Attempts should be made to determine the nature of the organism's pathogenicity in a given patient and appropriate therapy withheld or administered accordingly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199745"} {"pmid": "4199746", "title": "Multiple precipitation of sera containing monoclonal IgG proteins in radial immunodiffusion.", "content": "Multiple precipitation of sera containing monoclonal IgG proteins in radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199746"} {"pmid": "4199744", "title": "Trial of chloramphenicol for meningitis in northern savanna of Africa.", "content": "Trial of chloramphenicol for meningitis in northern savanna of Africa. In a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduced the cost and simplified treatment.It is suggested that chloramphenicol is a suitable alternative to sulphonamides for the treatment of meningococcal meningitis in those parts of Africa where the organism is sulphonamide-resistant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199744"} {"pmid": "4199749", "title": "Visually evoked responses in the rat, guinea pig, cat, monkey, and man.", "content": "Visually evoked responses in the rat, guinea pig, cat, monkey, and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199749"} {"pmid": "4199750", "title": "Delayed response deficits in squirrel monkeys with unilateral lesions in the midbrain reticular formation.", "content": "Delayed response deficits in squirrel monkeys with unilateral lesions in the midbrain reticular formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199750"} {"pmid": "4199751", "title": "Hippocampal lesions produced by prolonged seizures in paralyzed artificially ventilated baboons.", "content": "Hippocampal lesions produced by prolonged seizures in paralyzed artificially ventilated baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199751"} {"pmid": "4199752", "title": "Morphologic sex differences in primate brain areas involved in regulation of reproductive activity.", "content": "Morphologic sex differences in primate brain areas involved in regulation of reproductive activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199752"} {"pmid": "4199753", "title": "Activation of nisin production by UV-irradiation in a nisin-producing strain of Streptococcus lactis.", "content": "Activation of nisin production by UV-irradiation in a nisin-producing strain of Streptococcus lactis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199753"} {"pmid": "4199754", "title": "Regeneration of Drosophila melanogaster male leg disc fragments in sugar fed female hosts.", "content": "Regeneration of Drosophila melanogaster male leg disc fragments in sugar fed female hosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199754"} {"pmid": "4199755", "title": "The biological effects of the bark of Saccoglottis gabonensis Urban (Humiriaceae) on microorganisms.", "content": "The biological effects of the bark of Saccoglottis gabonensis Urban (Humiriaceae) on microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199755"} {"pmid": "4199757", "title": "Conformational changes following interaction between retinol isomers and human retinol-binding protein and between the retinol-binding protein and prealbumin.", "content": "Conformational changes following interaction between retinol isomers and human retinol-binding protein and between the retinol-binding protein and prealbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199757"} {"pmid": "4199758", "title": "Interactions of all-trans, 9-, 11-, and 13-cis-retinal, all-trans-retinyl acetate, and retinoic acid with human retinol-binding protein and prealbumin.", "content": "Interactions of all-trans, 9-, 11-, and 13-cis-retinal, all-trans-retinyl acetate, and retinoic acid with human retinol-binding protein and prealbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199758"} {"pmid": "4199759", "title": "Structure of a pentahexosylceramide (Forssman hapten) from canine intestine and kidney.", "content": "Structure of a pentahexosylceramide (Forssman hapten) from canine intestine and kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199759"} {"pmid": "4199760", "title": "Combined action of beta-lactum antibiotics against gram-negative bacilli.", "content": "Combined action of beta-lactum antibiotics against gram-negative bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199760"} {"pmid": "4199761", "title": "Experimental study of latency in typhus infection.", "content": "Experimental study of latency in typhus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199761"} {"pmid": "4199762", "title": "Immunological reactivity of chloramphenicol. I. Detection of antibodies, determination of levels and hypersensitivity.", "content": "Immunological reactivity of chloramphenicol. I. Detection of antibodies, determination of levels and hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199762"} {"pmid": "4199756", "title": "Australia antigen: current concepts.", "content": "Australia antigen: current concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199756"} {"pmid": "4199767", "title": "The gonococcus--a tough bug to grow.", "content": "The gonococcus--a tough bug to grow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199767"} {"pmid": "4199769", "title": "Metabolic acidosis in infants infused with commercial amino acid mixtures.", "content": "Metabolic acidosis in infants infused with commercial amino acid mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199769"} {"pmid": "4199770", "title": "Effects of maternal employment on the child. II.", "content": "Effects of maternal employment on the child. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199770"} {"pmid": "4199772", "title": "The genetics of blue-green algae.", "content": "The genetics of blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199772"} {"pmid": "4199773", "title": "Behavioral development after forelimb deafferentation on day of birth in monkeys with and without blinding.", "content": "Behavioral development after forelimb deafferentation on day of birth in monkeys with and without blinding. Four infant monkeys underwent somatosensory deafferentation of both forelimbs within hours after birth. Ambulation, climbing, and reaching toward objects developed spontaneously in each case. Thumb-forefinger prehension could be trained by operant shaping methods. Two infants deafferented at birth and blinded by eyelid closure were retarded in motor development by only 1 to 2 weeks. Results indicate that topographic sensory feedback and autogenetic spinal reflexes are not necessary after birth for the development of most types of movement performed by the forelimb musculature in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199773"} {"pmid": "4199774", "title": "Chlorhexidine as an inhibitor of pure bacterial and fungal cultures and dental plaque micro-organisms in sterilized saliva.", "content": "Chlorhexidine as an inhibitor of pure bacterial and fungal cultures and dental plaque micro-organisms in sterilized saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199774"} {"pmid": "4199775", "title": "Comparative biology of prokaryotic resting cells.", "content": "Comparative biology of prokaryotic resting cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199775"} {"pmid": "4199776", "title": "Histochemical interpretation of fluorescein angiogram. II. Background fluorescence and macular dark spot.", "content": "Histochemical interpretation of fluorescein angiogram. II. Background fluorescence and macular dark spot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199776"} {"pmid": "4199768", "title": "Diazepam as therapy for convulsive seizures precipitated by chemical intoxicants.", "content": "Diazepam as therapy for convulsive seizures precipitated by chemical intoxicants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199768"} {"pmid": "4199778", "title": "Ecology of entomogenous viruses and fungi.", "content": "Ecology of entomogenous viruses and fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199778"} {"pmid": "4199777", "title": "Experimental manipulation of desmosome structure.", "content": "Experimental manipulation of desmosome structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199777"} {"pmid": "4199779", "title": "Bacteria, spirochetes, and rickettsia as insecticides.", "content": "Bacteria, spirochetes, and rickettsia as insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199779"} {"pmid": "4199780", "title": "Increased aggregation of C-phycocyanin produced by phenol and benzene.", "content": "Increased aggregation of C-phycocyanin produced by phenol and benzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199780"} {"pmid": "4199781", "title": "The characterization of the RNAs and aminoacyl-tRNA synthetases of the blue-green alga, Anacystis nidulans.", "content": "The characterization of the RNAs and aminoacyl-tRNA synthetases of the blue-green alga, Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199781"} {"pmid": "4199782", "title": "Fractionation of ribonucleic acid by centrifugation in mixed sodium-potassium iodide density gradients.", "content": "Fractionation of ribonucleic acid by centrifugation in mixed sodium-potassium iodide density gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199782"} {"pmid": "4199783", "title": "A new intratypic variant of coxsackie B6 virus.", "content": "A new intratypic variant of coxsackie B6 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199783"} {"pmid": "4199795", "title": "Screening tests for argininosuccinic aciduria, orotic aciduria, and other inherited enzyme deficiencies using dried blood specimens.", "content": "Screening tests for argininosuccinic aciduria, orotic aciduria, and other inherited enzyme deficiencies using dried blood specimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199795"} {"pmid": "4199796", "title": "Alkaline phosphatase of Drosophila melanogaster. I. Partial purification and characterization.", "content": "Alkaline phosphatase of Drosophila melanogaster. I. Partial purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199796"} {"pmid": "4199798", "title": "Esterase polymorphisms in Microtus ochrogaster: interaction and linkage.", "content": "Esterase polymorphisms in Microtus ochrogaster: interaction and linkage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199798"} {"pmid": "4199797", "title": "Morphogenic effects of halogenated thymidine analogues on Drosophila. I. Quantitative analysis of lesions induced by 5-bromodeoxyuridine and 5-fluorouracil.", "content": "Morphogenic effects of halogenated thymidine analogues on Drosophila. I. Quantitative analysis of lesions induced by 5-bromodeoxyuridine and 5-fluorouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199797"} {"pmid": "4199799", "title": "Induction of null-activity mutants for the acid phosphatase-1 gene in Drosophila melanogaster.", "content": "Induction of null-activity mutants for the acid phosphatase-1 gene in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199799"} {"pmid": "4199800", "title": "Levels of RNA and DNA in Drosophila melanogaster at different stages of development: a comparison between one bobbed and two phenotypically non-bobbed stocks.", "content": "Levels of RNA and DNA in Drosophila melanogaster at different stages of development: a comparison between one bobbed and two phenotypically non-bobbed stocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199800"} {"pmid": "4199801", "title": "Molecular pathology of ceruloplasmin.", "content": "Molecular pathology of ceruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199801"} {"pmid": "4199802", "title": "Distribution of erythrocyte carbonic anhydrase B-type alleles in Japanese farm horses.", "content": "Distribution of erythrocyte carbonic anhydrase B-type alleles in Japanese farm horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199802"} {"pmid": "4199805", "title": "Conformational studies of nucleoprotein. Circular dichroism of deoxyribonucleic acid base pairs bound by polylysine.", "content": "Conformational studies of nucleoprotein. Circular dichroism of deoxyribonucleic acid base pairs bound by polylysine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199805"} {"pmid": "4199806", "title": "Cross-linking of elongation factor EF-G to the 50S ribosomal subunit of Escherichia coli.", "content": "Cross-linking of elongation factor EF-G to the 50S ribosomal subunit of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199806"} {"pmid": "4199803", "title": "Mitochondria and chloroplasts as descendants of prokaryotes.", "content": "Mitochondria and chloroplasts as descendants of prokaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199803"} {"pmid": "4199807", "title": "Neurofibrosarcoma of the orbit (malignant change in a plexiform neurofibromatosis).", "content": "Neurofibrosarcoma of the orbit (malignant change in a plexiform neurofibromatosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199807"} {"pmid": "4199804", "title": "Genome amplification and gene expression in the ciliate macronucleus.", "content": "Genome amplification and gene expression in the ciliate macronucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199804"} {"pmid": "4199808", "title": "Effect of cocaine on Na channel in toad skin.", "content": "Effect of cocaine on Na channel in toad skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199808"} {"pmid": "4199809", "title": "Differential cytotoxicity of activated lymphocytes on allogeneic and xenogeneic target cells. II. Activation by phytohemagglutinin.", "content": "Differential cytotoxicity of activated lymphocytes on allogeneic and xenogeneic target cells. II. Activation by phytohemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199809"} {"pmid": "4199810", "title": "Survival and function of bursa-derived cells in bursectomized chickens.", "content": "Survival and function of bursa-derived cells in bursectomized chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199810"} {"pmid": "4199811", "title": "Replicating DNA molecules from eggs of Drosophila melanogaster.", "content": "Replicating DNA molecules from eggs of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199811"} {"pmid": "4199813", "title": "Immunological analysis of acidic proteins in the chromatin of Ehrlich ascites tumor cells.", "content": "Immunological analysis of acidic proteins in the chromatin of Ehrlich ascites tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199813"} {"pmid": "4199814", "title": "Disappearance of multiple esophageal diverticula following treatment of esophagitis: serial endoscopic, manometric, and radiologic observations.", "content": "Disappearance of multiple esophageal diverticula following treatment of esophagitis: serial endoscopic, manometric, and radiologic observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199814"} {"pmid": "4199817", "title": "Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled (1-3H)cadaverine.", "content": "Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled (1-3H)cadaverine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199817"} {"pmid": "4199818", "title": "Automated photometric microbiological assay for monensin in poultry rations.", "content": "Automated photometric microbiological assay for monensin in poultry rations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199818"} {"pmid": "4199819", "title": "Infrared studies of DDT, structurally related halogenated pesticides, and some metabolites.", "content": "Infrared studies of DDT, structurally related halogenated pesticides, and some metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199819"} {"pmid": "4199820", "title": "Collaborative study of a colorimetric determination of nitroglycerin in sublingual tablets.", "content": "Collaborative study of a colorimetric determination of nitroglycerin in sublingual tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199820"} {"pmid": "4199821", "title": "Turbidimetric evaluation of bacterial culture resistance in disinfectant testing.", "content": "Turbidimetric evaluation of bacterial culture resistance in disinfectant testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199821"} {"pmid": "4199830", "title": "The death rate of lysogenic bacteria after ultraviolet induction follows Gompertz's law.", "content": "The death rate of lysogenic bacteria after ultraviolet induction follows Gompertz's law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199830"} {"pmid": "4199831", "title": "Recent evidence on tRNA and tRNA acylase-mediated cellular control mechanisms: a review.", "content": "Recent evidence on tRNA and tRNA acylase-mediated cellular control mechanisms: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199831"} {"pmid": "4199845", "title": "Intrahepatic localisation of Australia antigen by fluorescent antibody technique.", "content": "Intrahepatic localisation of Australia antigen by fluorescent antibody technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199845"} {"pmid": "4199846", "title": "Quantitative studies of Australia antigen in acute and chronic hepatitis. Evidence for an inverse relationship between circulating Au-antigen and transaminase values in patients with progression from acute to chronic hepatitis.", "content": "Quantitative studies of Australia antigen in acute and chronic hepatitis. Evidence for an inverse relationship between circulating Au-antigen and transaminase values in patients with progression from acute to chronic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199846"} {"pmid": "4199847", "title": "WHO Expert Committee on Biological Standardization: twenty-fifth report.", "content": "WHO Expert Committee on Biological Standardization: twenty-fifth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199847"} {"pmid": "4199851", "title": "Ultrastructural studies of spermatogenesis in Drosophila melanogaster Meigen.", "content": "Ultrastructural studies of spermatogenesis in Drosophila melanogaster Meigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199851"} {"pmid": "4199850", "title": "Ultrastructural study on contractile structures in mammalian nephron. Their development in the metanephros of human embryo.", "content": "Ultrastructural study on contractile structures in mammalian nephron. Their development in the metanephros of human embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199850"} {"pmid": "4199853", "title": "Cholinesterase-containing nerve fibres on blood vessels in lungs of some laboratory mammals.", "content": "Cholinesterase-containing nerve fibres on blood vessels in lungs of some laboratory mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199853"} {"pmid": "4199854", "title": "Regulation of tRNA.", "content": "Regulation of tRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199854"} {"pmid": "4199855", "title": "Factors affecting the zinc content of E. coli alkaline phosphatase.", "content": "Factors affecting the zinc content of E. coli alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199855"} {"pmid": "4199856", "title": "Partial purification and properties of a nucleoside hydrolase from Crithidia.", "content": "Partial purification and properties of a nucleoside hydrolase from Crithidia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199856"} {"pmid": "4199857", "title": "Activation of glutaraldehyde-crosslinked chymotrypsinogen-A. Enzymatic activity and circular dichroism studies.", "content": "Activation of glutaraldehyde-crosslinked chymotrypsinogen-A. Enzymatic activity and circular dichroism studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199857"} {"pmid": "4199858", "title": "Purification and properties of enolase from swine kidney.", "content": "Purification and properties of enolase from swine kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199858"} {"pmid": "4199859", "title": "Triosephosphate isomerases and aldolases from light- and dark-grown Euglena gracilis.", "content": "Triosephosphate isomerases and aldolases from light- and dark-grown Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199859"} {"pmid": "4199861", "title": "Immunoglobulins of colostrum. I. Preparation and identification of ovine colostral immunoglobulins.", "content": "Immunoglobulins of colostrum. I. Preparation and identification of ovine colostral immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199861"} {"pmid": "4199862", "title": "Immunization of animals with Australia antigen.", "content": "Immunization of animals with Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199862"} {"pmid": "4199863", "title": "Possible linkage relationships between certain blood groups and schizophrenia or other psychoses.", "content": "Possible linkage relationships between certain blood groups and schizophrenia or other psychoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199863"} {"pmid": "4199864", "title": "Effects of genetic variation and culture conditions on the social behavior of Drosophila melanogaster.", "content": "Effects of genetic variation and culture conditions on the social behavior of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199864"} {"pmid": "4199866", "title": "Prostaglandin synthesis by the pregnant rat uterus at term and its possible relevance in parturition.", "content": "Prostaglandin synthesis by the pregnant rat uterus at term and its possible relevance in parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199866"} {"pmid": "4199865", "title": "The distribution and induction of some drug-metabolizing enzymes in man.", "content": "The distribution and induction of some drug-metabolizing enzymes in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199865"} {"pmid": "4199867", "title": "Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis.", "content": "Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199867"} {"pmid": "4199868", "title": "Effects of indomethacin on rat gastric acid secretion and mucosal blood flow.", "content": "Effects of indomethacin on rat gastric acid secretion and mucosal blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199868"} {"pmid": "4199873", "title": "Platelet diphenoloxidases in progressive muscular dystrophy (P.M.D.).", "content": "Platelet diphenoloxidases in progressive muscular dystrophy (P.M.D.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199873"} {"pmid": "4199874", "title": "Androgen-induced social dominance in infant female rhesus monkeys.", "content": "Androgen-induced social dominance in infant female rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199874"} {"pmid": "4199881", "title": "Care of the neurogenic bladder.", "content": "Care of the neurogenic bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199881"} {"pmid": "4199880", "title": "The general practitioner and the Oncology Organization.", "content": "The general practitioner and the Oncology Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199880"} {"pmid": "4199886", "title": "Sarcocysts in the heart muscle of a foal.", "content": "Sarcocysts in the heart muscle of a foal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199886"} {"pmid": "4199887", "title": "Advances in methods of fertility regulation: report of a WHO scientific group.", "content": "Advances in methods of fertility regulation: report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199887"} {"pmid": "4199888", "title": "Use of disodium cromoglycate during the course of specific desensitizing treatment in asthmatic patients.", "content": "Use of disodium cromoglycate during the course of specific desensitizing treatment in asthmatic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199888"} {"pmid": "4199889", "title": "Physiological gradients in development. A possible role for messenger ribonucleoprotein.", "content": "Physiological gradients in development. A possible role for messenger ribonucleoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199889"} {"pmid": "4199891", "title": "Reaction of bovine and ovine pituitary growth hormones with tetranitromethane.", "content": "Reaction of bovine and ovine pituitary growth hormones with tetranitromethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199891"} {"pmid": "4199892", "title": "Light-scattering effects on the circular dichroism of chloroplasts.", "content": "Light-scattering effects on the circular dichroism of chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199892"} {"pmid": "4199894", "title": "Relationships among enzymes of the beta-ketoadipate pathway. I. Properties of cis,cis-muconate-lactonizing enzyme and muconolactone isomerase from Pseudomonas putida.", "content": "Relationships among enzymes of the beta-ketoadipate pathway. I. Properties of cis,cis-muconate-lactonizing enzyme and muconolactone isomerase from Pseudomonas putida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199894"} {"pmid": "4199893", "title": "Growth, isolation, and characterization of a yeast manganese alcohol dehydrogenase.", "content": "Growth, isolation, and characterization of a yeast manganese alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199893"} {"pmid": "4199895", "title": "Relationships among enzymes of the beta-ketoadipate pathway. II. Properties of crystalline beta-carboxy-cis,cis-muconate-lactonizing enzyme from Pseudomonas putida.", "content": "Relationships among enzymes of the beta-ketoadipate pathway. II. Properties of crystalline beta-carboxy-cis,cis-muconate-lactonizing enzyme from Pseudomonas putida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199895"} {"pmid": "4199897", "title": "Specialized paranodal and interparanodal glial-axonal junctions in the peripheral and central nervous system: a freeze-etching study.", "content": "Specialized paranodal and interparanodal glial-axonal junctions in the peripheral and central nervous system: a freeze-etching study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199897"} {"pmid": "4199896", "title": "Relationships among enzymes of the beta-ketoadipate pathway. 3. Properties of crystalline gamma-carboxymuconolactone decarboxylase from Pseudomonas putida.", "content": "Relationships among enzymes of the beta-ketoadipate pathway. 3. Properties of crystalline gamma-carboxymuconolactone decarboxylase from Pseudomonas putida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199896"} {"pmid": "4199898", "title": "Alterations of spatio-tactile discrimination after lesions of primate spinal cord.", "content": "Alterations of spatio-tactile discrimination after lesions of primate spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199898"} {"pmid": "4199900", "title": "Evidence for LH and FSH binding protein(s) in human and rat serum.", "content": "Evidence for LH and FSH binding protein(s) in human and rat serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199900"} {"pmid": "4199901", "title": "Effects of testosterone oenanthate on plasma concentrations of thyroxine, cortisol, testosterone and hormone binding proteins in patients with hypogonadism.", "content": "Effects of testosterone oenanthate on plasma concentrations of thyroxine, cortisol, testosterone and hormone binding proteins in patients with hypogonadism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199901"} {"pmid": "4199902", "title": "Reduced plasma thyrotropin response to thyrotropin releasing hormone after dexamethasone administration in normal subjects.", "content": "Reduced plasma thyrotropin response to thyrotropin releasing hormone after dexamethasone administration in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199902"} {"pmid": "4199903", "title": "Glucose, FFA, IRI and GH response to I.V. glibenclamide.", "content": "Glucose, FFA, IRI and GH response to I.V. glibenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199903"} {"pmid": "4199904", "title": "Adverse reactions of antirheumatic drugs.", "content": "Adverse reactions of antirheumatic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199904"} {"pmid": "4199906", "title": "Differences in access into the central nervous system of ME7 scrapie agent from two strains of mice.", "content": "Differences in access into the central nervous system of ME7 scrapie agent from two strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199906"} {"pmid": "4199907", "title": "Scrapie in mice. Some effects on the brain lesion profile of ME7 agent due to genotype of donor, route of injection and genotype of recipient.", "content": "Scrapie in mice. Some effects on the brain lesion profile of ME7 agent due to genotype of donor, route of injection and genotype of recipient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199907"} {"pmid": "4199908", "title": "Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation.", "content": "Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199908"} {"pmid": "4199909", "title": "Non-specific agglutination of Mycoplasma gallisepticum by rheumatoid factor-like antiglobulin in chickens infected with Streptococcus faecalis or Staphylococcus aureus.", "content": "Non-specific agglutination of Mycoplasma gallisepticum by rheumatoid factor-like antiglobulin in chickens infected with Streptococcus faecalis or Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199909"} {"pmid": "4199910", "title": "Levels of IgM and IgG in the sera of normal and leukaemic calves.", "content": "Levels of IgM and IgG in the sera of normal and leukaemic calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199910"} {"pmid": "4199911", "title": "Further evidence of plasma membrane material in skim milk.", "content": "Further evidence of plasma membrane material in skim milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199911"} {"pmid": "4199913", "title": "Experimental brain death. I. Morphology and fine structure of the brain.", "content": "Experimental brain death. I. Morphology and fine structure of the brain. The morphological characteristics of brain death were examined in baboons and cats after artificial cerebral ischaemia. All animals showed autolytic changes in the brain, ischaemic neuronal changes, midbrain haemorrhages, focal necrosis of the brain-stem, demarcation at C 1/C 2 cord segment, and displacement of cerebellar tissue. Ultrastructural examination revealed extreme brain oedema, autolytic changes, and complete obstruction of capillaries by astrocytic and endothelial swelling and intravascular blebs. These data indicate that brain death develops in several stages. If the process starts in the supratentorial space it first leads to a breakdown of the cerebral circulation and to transtentorial herniation. As a result, midbrain haemorrhages develop and the infratentorial pressure begins to rise. The second stage is terminated by demarcation of the brain. The circulatory arrest is initially caused by venous compression but becomes irreversible when vascular obstruction develops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199913"} {"pmid": "4199914", "title": "Blood parasites of Pekin Robins (Liothrix luteus).", "content": "Blood parasites of Pekin Robins (Liothrix luteus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199914"} {"pmid": "4199915", "title": "Zschokkella floridanae sp. n. (Myxosporidea) from the goldspotted killifish, Floridichthys carpio (Günther).", "content": "Zschokkella floridanae sp. n. (Myxosporidea) from the goldspotted killifish, Floridichthys carpio (Günther).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199915"} {"pmid": "4199916", "title": "Effects of glutaraldehyde and osmium tetroxide on hypotrichous ciliates, and determination of the most satisfactory fixation methods for electron microscopy.", "content": "Effects of glutaraldehyde and osmium tetroxide on hypotrichous ciliates, and determination of the most satisfactory fixation methods for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199916"} {"pmid": "4199917", "title": "Haematozoa in domestic chickens and guinea fowl in Tanzania and transmission of Leucocytozoon neavei and Leucocytozoon schoutedeni.", "content": "Haematozoa in domestic chickens and guinea fowl in Tanzania and transmission of Leucocytozoon neavei and Leucocytozoon schoutedeni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199917"} {"pmid": "4199918", "title": "The polychlorinated biphenyls Aroclors 1248 and 1260: effect on and accumulation by Tetrahymena pyriformis.", "content": "The polychlorinated biphenyls Aroclors 1248 and 1260: effect on and accumulation by Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199918"} {"pmid": "4199920", "title": "Variation in glyoxylate bypass inducibility among strains of Tetrahymena pyriformis.", "content": "Variation in glyoxylate bypass inducibility among strains of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199920"} {"pmid": "4199919", "title": "Hydroxyproline in Tetrahymena.", "content": "Hydroxyproline in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199919"} {"pmid": "4199921", "title": "The prognosis following surgical removal of mastocytomas in dogs.", "content": "The prognosis following surgical removal of mastocytomas in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199921"} {"pmid": "4199922", "title": "Biodegradation of oleates.", "content": "Biodegradation of oleates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199922"} {"pmid": "4199925", "title": "Thiazides and hypokalaemia in diabetic ketoacidosis.", "content": "Thiazides and hypokalaemia in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199925"} {"pmid": "4199932", "title": "Studies on Fes, a mutation affecting cystocyte cytokinesis, in Drosophilia melanogaster.", "content": "Studies on Fes, a mutation affecting cystocyte cytokinesis, in Drosophilia melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199932"} {"pmid": "4199931", "title": "Relative safety of self inflicted overdose with relatively newer medications.", "content": "Relative safety of self inflicted overdose with relatively newer medications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199931"} {"pmid": "4199933", "title": "Aggregation of horseshoe crab (Limulus polyphemus) amebocytes and reversible inhibition of aggregation by EDTA.", "content": "Aggregation of horseshoe crab (Limulus polyphemus) amebocytes and reversible inhibition of aggregation by EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199933"} {"pmid": "4199926", "title": "Occlusion of the posterior ciliary arteries.", "content": "Occlusion of the posterior ciliary arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199926"} {"pmid": "4199936", "title": "The effects of inhibition of protein synthesis on the phenotype of Abnormal-abdomen.", "content": "The effects of inhibition of protein synthesis on the phenotype of Abnormal-abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199936"} {"pmid": "4199937", "title": "Multiple gene control of the tRNA aminoacylating system in Drosophila melanogaster.", "content": "Multiple gene control of the tRNA aminoacylating system in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199937"} {"pmid": "4199938", "title": "A new sex factor of Pseudomonas aeruginosa.", "content": "A new sex factor of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199938"} {"pmid": "4199939", "title": "Isolation of a transducing phage forming plaques on Pseudomonas maltophilia and Pseudomonas aeruginosa.", "content": "Isolation of a transducing phage forming plaques on Pseudomonas maltophilia and Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199939"} {"pmid": "4199950", "title": "Possible human-animal paranormal events.", "content": "Possible human-animal paranormal events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199950"} {"pmid": "4199951", "title": "Benthic marine and blue-green algal species as a source of choline.", "content": "Benthic marine and blue-green algal species as a source of choline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199951"} {"pmid": "4199959", "title": "A neural system analysis of memory storage and retrieval.", "content": "A neural system analysis of memory storage and retrieval.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199959"} {"pmid": "4199960", "title": "The utilization of bacteria as food for Paramecium bursaria.", "content": "The utilization of bacteria as food for Paramecium bursaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199960"} {"pmid": "4199962", "title": "Intraluminal duodenal diverticulum in a child.", "content": "Intraluminal duodenal diverticulum in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199962"} {"pmid": "4199970", "title": "Plasma epinephrine and plasma norepinephrine concentrations in early diabetes.", "content": "Plasma epinephrine and plasma norepinephrine concentrations in early diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199970"} {"pmid": "4199971", "title": "The drosopterin pattern in various eye color mutants of the fruitfly. Drosophila melanogaster.", "content": "The drosopterin pattern in various eye color mutants of the fruitfly. Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199971"} {"pmid": "4199972", "title": "Maternal effects on x-ray-induced sex chromosome loss in mature sperm of Drosophila melanogaster: a storage effect in mature oocytes.", "content": "Maternal effects on x-ray-induced sex chromosome loss in mature sperm of Drosophila melanogaster: a storage effect in mature oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199972"} {"pmid": "4199958", "title": "Simultaneous bilateral focal seizures without loss of consciousness.", "content": "Simultaneous bilateral focal seizures without loss of consciousness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199958"} {"pmid": "4199985", "title": "Dominance measurements of low and high protein reared rhesus macaques.", "content": "Dominance measurements of low and high protein reared rhesus macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199985"} {"pmid": "4199987", "title": "Size heterogeneity of human IgA myeloma proteins. Relationships between polymers and \"J\" chain.", "content": "Size heterogeneity of human IgA myeloma proteins. Relationships between polymers and \"J\" chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199987"} {"pmid": "4199986", "title": "On the specificity of Pseudomonas aeruginosa alkaline proteinase with synthetic peptides.", "content": "On the specificity of Pseudomonas aeruginosa alkaline proteinase with synthetic peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199986"} {"pmid": "4199988", "title": "Selective activation of T lymphocytes. Its possible application in the immunomanipulation of tumours.", "content": "Selective activation of T lymphocytes. Its possible application in the immunomanipulation of tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4199988"} {"pmid": "4200007", "title": "East Coast fever: the infectivity for cattle of infective particles of Theileria parva harvested in various substrates.", "content": "East Coast fever: the infectivity for cattle of infective particles of Theileria parva harvested in various substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200007"} {"pmid": "4200008", "title": "Babesia argentina: intraerythrocytic location of babesial antigen extracted from parasite suspensions.", "content": "Babesia argentina: intraerythrocytic location of babesial antigen extracted from parasite suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200008"} {"pmid": "4200009", "title": "Characterization of a glycoprotein in the cyst fluid of Cysticercus tenuicollis from the goat.", "content": "Characterization of a glycoprotein in the cyst fluid of Cysticercus tenuicollis from the goat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200009"} {"pmid": "4200011", "title": "Isolation of blood-stage merozoites from Plasmodium knowlesi malaria.", "content": "Isolation of blood-stage merozoites from Plasmodium knowlesi malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200011"} {"pmid": "4200010", "title": "The responses to various stimuli of microfilariae of Dirofilaria corynodes, of Dipetalonema marmosetae and of unidentified species of filariae in Saimiri sciureus and Cacajao monkeys.", "content": "The responses to various stimuli of microfilariae of Dirofilaria corynodes, of Dipetalonema marmosetae and of unidentified species of filariae in Saimiri sciureus and Cacajao monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200010"} {"pmid": "4200012", "title": "Measuring health care.", "content": "Measuring health care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200012"} {"pmid": "4200013", "title": "The establishment and maintenance of a small, inexpensive baboon colony for behavioral research.", "content": "The establishment and maintenance of a small, inexpensive baboon colony for behavioral research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200013"} {"pmid": "4200014", "title": "Gastric pseudoadenomyosis in a Macaca mulatta.", "content": "Gastric pseudoadenomyosis in a Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200014"} {"pmid": "4200015", "title": "Progesterone levels in the Sooty mangabey (Cercocebus atys) during the menstrual cycle, pregnancy and parturition.", "content": "Progesterone levels in the Sooty mangabey (Cercocebus atys) during the menstrual cycle, pregnancy and parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200015"} {"pmid": "4200016", "title": "Aortic intimal lesions and serum lipids in wild baboons.", "content": "Aortic intimal lesions and serum lipids in wild baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200016"} {"pmid": "4200017", "title": "Convenient sites for venipuncture in smaller primates.", "content": "Convenient sites for venipuncture in smaller primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200017"} {"pmid": "4200018", "title": "Precursors of 5 S ribosomal RNA in Bacillus subtilis.", "content": "Precursors of 5 S ribosomal RNA in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200018"} {"pmid": "4200019", "title": "Whole-body retention of 65Zn after single and daily oral administration in young and adult mice.", "content": "Whole-body retention of 65Zn after single and daily oral administration in young and adult mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200019"} {"pmid": "4200027", "title": "Psychiatric and psychological research in the Navy before World War II.", "content": "Psychiatric and psychological research in the Navy before World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200027"} {"pmid": "4200028", "title": "An alternative method of flap reflection for mandibular third molars.", "content": "An alternative method of flap reflection for mandibular third molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200028"} {"pmid": "4200029", "title": "Acinic cell adenocarcinoma of minor salivary gland origin.", "content": "Acinic cell adenocarcinoma of minor salivary gland origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200029"} {"pmid": "4200032", "title": "Optometry: ophthalmology's obligation.", "content": "Optometry: ophthalmology's obligation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200032"} {"pmid": "4200034", "title": "Serum triiodothyronine, total thyroxine, and thyroxine to triiodothyronine ratios in paired maternal-cord sera and at one week and one month of age.", "content": "Serum triiodothyronine, total thyroxine, and thyroxine to triiodothyronine ratios in paired maternal-cord sera and at one week and one month of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200034"} {"pmid": "4200041", "title": "Electromyography of the oral phase of deglutition in the Rhesus monkey (Macaca mulatta).", "content": "Electromyography of the oral phase of deglutition in the Rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200041"} {"pmid": "4200043", "title": "Effect of prostaglandins on oviduct motility in estrous rabbits.", "content": "Effect of prostaglandins on oviduct motility in estrous rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200043"} {"pmid": "4200040", "title": "Growth inhibition by L-phenylalanine in Agmenellum quadruplicatum. A clue to some amino acid interrelationships.", "content": "Growth inhibition by L-phenylalanine in Agmenellum quadruplicatum. A clue to some amino acid interrelationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200040"} {"pmid": "4200042", "title": "Metabolism and function of polyisoprenol sugar intermediates in membrane-associated reactions.", "content": "Metabolism and function of polyisoprenol sugar intermediates in membrane-associated reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200042"} {"pmid": "4200049", "title": "The effects of ethanol on the liver.", "content": "The effects of ethanol on the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200049"} {"pmid": "4200050", "title": "Immunochemical studies on cobrotoxin.", "content": "Immunochemical studies on cobrotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200050"} {"pmid": "4200051", "title": "Production of anti-idiotypic and anti-class specific antibody using micro amounds of myeloma serum.", "content": "Production of anti-idiotypic and anti-class specific antibody using micro amounds of myeloma serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200051"} {"pmid": "4200038", "title": "Corneal pathogenicity of Serratia marcescens in the rabbit.", "content": "Corneal pathogenicity of Serratia marcescens in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200038"} {"pmid": "4200056", "title": "Improved methods of non-oral neonatal feeding: a commentary.", "content": "Improved methods of non-oral neonatal feeding: a commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200056"} {"pmid": "4200059", "title": "Research on dengue in tissue culture. V. Production of anti-dengue antibodies in tissue cultures from monkeys inoculated with an attenuated type I dengue virus strain.", "content": "Research on dengue in tissue culture. V. Production of anti-dengue antibodies in tissue cultures from monkeys inoculated with an attenuated type I dengue virus strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200059"} {"pmid": "4200060", "title": "Pathogenesis and immunity of dengue infection in man.", "content": "Pathogenesis and immunity of dengue infection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200060"} {"pmid": "4200061", "title": "Effect of synthetic thyrotropin-releasing factor (TRF) on pituitary TSH secretion in man, with special reference to the evaluation for TRF test.", "content": "Effect of synthetic thyrotropin-releasing factor (TRF) on pituitary TSH secretion in man, with special reference to the evaluation for TRF test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200061"} {"pmid": "4200062", "title": "If your patient can't tolerate the cold--suspect cryoglobulinemia.", "content": "If your patient can't tolerate the cold--suspect cryoglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200062"} {"pmid": "4200071", "title": "Federal Medical Chiefs on progress and plans: Department of Defense.", "content": "Federal Medical Chiefs on progress and plans: Department of Defense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200071"} {"pmid": "4200072", "title": "Federal Medical Chiefs on progress and plans: Department of Health, Education, and Welfare.", "content": "Federal Medical Chiefs on progress and plans: Department of Health, Education, and Welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200072"} {"pmid": "4200073", "title": "Federal Medical Chiefs on progress and plans: Army Medical Department.", "content": "Federal Medical Chiefs on progress and plans: Army Medical Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200073"} {"pmid": "4200074", "title": "Federal Medical Chiefs on progress and plans: Navy Medical Department.", "content": "Federal Medical Chiefs on progress and plans: Navy Medical Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200074"} {"pmid": "4200075", "title": "Federal Medical Chiefs on progress and plans: Air Force Medical Services.", "content": "Federal Medical Chiefs on progress and plans: Air Force Medical Services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200075"} {"pmid": "4200076", "title": "Federal Medical Chiefs on progress and plans: Veterans Administration.", "content": "Federal Medical Chiefs on progress and plans: Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200076"} {"pmid": "4200078", "title": "Preliminary report: comprehensive screening and education for sickle cell anemia.", "content": "Preliminary report: comprehensive screening and education for sickle cell anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200078"} {"pmid": "4200077", "title": "Experience with mixed infections of Plasmodium falciparum and vivax.", "content": "Experience with mixed infections of Plasmodium falciparum and vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200077"} {"pmid": "4200079", "title": "Phencyclidine induced psychosis. The need to avoid unnecessary sensory influx.", "content": "Phencyclidine induced psychosis. The need to avoid unnecessary sensory influx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200079"} {"pmid": "4200080", "title": "Low-cost system of dispensing solutions to parallel-flow dialyzers.", "content": "Low-cost system of dispensing solutions to parallel-flow dialyzers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200080"} {"pmid": "4200081", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200081"} {"pmid": "4200082", "title": "Prolongation of active useful life.", "content": "Prolongation of active useful life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200082"} {"pmid": "4200084", "title": "Maternal dietary supplementation and infant birth weight.", "content": "Maternal dietary supplementation and infant birth weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200084"} {"pmid": "4200085", "title": "Discrimination learning without reward.", "content": "Discrimination learning without reward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200085"} {"pmid": "4200088", "title": "WHO expert committee on drug dependence. Nineteenth report.", "content": "WHO expert committee on drug dependence. Nineteenth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200088"} {"pmid": "4200089", "title": "Chemotherapy of malaria and resistance to antimalarials. Report of a WHO scientific group.", "content": "Chemotherapy of malaria and resistance to antimalarials. Report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200089"} {"pmid": "4200091", "title": "Observations following high intensity white light exposure to the retina.", "content": "Observations following high intensity white light exposure to the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200091"} {"pmid": "4200093", "title": "Abrasion of composite restorative material.", "content": "Abrasion of composite restorative material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200093"} {"pmid": "4200092", "title": "Limits for single cell protein utilization in human feeding.", "content": "Limits for single cell protein utilization in human feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200092"} {"pmid": "4200094", "title": "An evaluation of nitrous oxide oxygen analgesia after two years of use.", "content": "An evaluation of nitrous oxide oxygen analgesia after two years of use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200094"} {"pmid": "4200095", "title": "Prescribing supplemental fluorine in fluoride deficient water suppliers.", "content": "Prescribing supplemental fluorine in fluoride deficient water suppliers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200095"} {"pmid": "4200096", "title": "Isozyme variability in species of the genus Drosophila. VI. Frequency-property-environment relationships of allelic alcohol dehydrogenases in D. melanogaster.", "content": "Isozyme variability in species of the genus Drosophila. VI. Frequency-property-environment relationships of allelic alcohol dehydrogenases in D. melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200096"} {"pmid": "4200097", "title": "A novel hypoglycemic compound.", "content": "A novel hypoglycemic compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200097"} {"pmid": "4200098", "title": "The basis for progress in chemotherapy.", "content": "The basis for progress in chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200098"} {"pmid": "4200099", "title": "Cancer chemotherapeutic agents.", "content": "Cancer chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200099"} {"pmid": "4200100", "title": "L-asparaginase for the treatment of cancer.", "content": "L-asparaginase for the treatment of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200100"} {"pmid": "4200101", "title": "Chemotherapy of skin cancer.", "content": "Chemotherapy of skin cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200101"} {"pmid": "4200114", "title": "Chronic recurrent pancreatitis and pancreatic pseudocysts.", "content": "Chronic recurrent pancreatitis and pancreatic pseudocysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200114"} {"pmid": "4200115", "title": "Effects of progesterone on the ocular hypertensive response to prostaglandin.", "content": "Effects of progesterone on the ocular hypertensive response to prostaglandin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200115"} {"pmid": "4200116", "title": "Detection of small amounts of pesticides in human biological material by thin-layer chromatography.", "content": "Detection of small amounts of pesticides in human biological material by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200116"} {"pmid": "4200102", "title": "A chemotherapy-radiotherapy Rx regimen for children with stage 3 Hodgkin's disease.", "content": "A chemotherapy-radiotherapy Rx regimen for children with stage 3 Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200102"} {"pmid": "4200104", "title": "A personal tribute to Sidney Farber, M.D. (1903-1973).", "content": "A personal tribute to Sidney Farber, M.D. (1903-1973).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200104"} {"pmid": "4200118", "title": "Protein A from Staphylococcus aureus. XVI. Alkylation with iodoacetic acid at different pH-values.", "content": "Protein A from Staphylococcus aureus. XVI. Alkylation with iodoacetic acid at different pH-values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200118"} {"pmid": "4200119", "title": "The purification of human polyclonal IgE by immunosorption.", "content": "The purification of human polyclonal IgE by immunosorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200119"} {"pmid": "4200120", "title": "Quantitative studies on the interaction of concanavalin A, the carbohydrate-binding protein of the jack bean, with model carbohydrate-protein conjugates.", "content": "Quantitative studies on the interaction of concanavalin A, the carbohydrate-binding protein of the jack bean, with model carbohydrate-protein conjugates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200120"} {"pmid": "4200122", "title": "J chain in pig immunoglobulins.", "content": "J chain in pig immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200122"} {"pmid": "4200121", "title": "Active sites of turtle and duck low molecular weight antibody to 2'4'dinitrophenol.", "content": "Active sites of turtle and duck low molecular weight antibody to 2'4'dinitrophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200121"} {"pmid": "4200123", "title": "Early interactions between inhibitors and antibodies to lysozyme.", "content": "Early interactions between inhibitors and antibodies to lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200123"} {"pmid": "4200124", "title": "Equine anti-hapten antibody. VII. Anti-lactoside antibody induced by a bacterial vaccine.", "content": "Equine anti-hapten antibody. VII. Anti-lactoside antibody induced by a bacterial vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200124"} {"pmid": "4200125", "title": "Rabbit -fetoprotein: immunochemical purification and partial characterization.", "content": "Rabbit -fetoprotein: immunochemical purification and partial characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200125"} {"pmid": "4200126", "title": "Immunochemical analysis of rat brain microsomes.", "content": "Immunochemical analysis of rat brain microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200126"} {"pmid": "4200127", "title": "Detection of the e14 and e15 rabbit allotypic specificities by immunodiffusion in PEG agar.", "content": "Detection of the e14 and e15 rabbit allotypic specificities by immunodiffusion in PEG agar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200127"} {"pmid": "4200128", "title": "Effect of cycloheximide on L-leucine transport by Penicillium chrysogenum: involvement of calcium.", "content": "Effect of cycloheximide on L-leucine transport by Penicillium chrysogenum: involvement of calcium. Cycloheximide (actidione) has an immediate inhibitory effect on amino acid transport by nitrogen-starved or carbon-starved mycelium suspended in phosphate buffer. High concentrations of phosphate alone are slightly inhibitory; cycloheximide appears to potentiate the effect of phosphate. Ca(2+) reverses the inhibition of transport caused by phosphate plus cycloheximide. Ca(2+) did not relieve the inhibition of protein synthesis. Cycloheximide promotes a continual uptake of (45)Ca(2+) by the mycelium. The cumulative results suggest that (i) membrane-bound Ca(2+) is involved in amino acid transport, (ii) cycloheximide labilizes the membrane-bound Ca(2+), and (iii) phosphate forms a complex with Ca(2+) making it unavailable for its role in transport. The effect of cycloheximide described above is observed within 1 to 2 min after addition of the antibiotic. This initial inhibition occurs more rapidly with 10(-3) M cycloheximide than with 10(-5) M cycloheximide. However, after a longer preincubation time, a curious inverse relationship between cycloheximide concentration and amino acid transport is observed. The mycelium incubated with 10(-5) M cycloheximide remains strongly inhibited (unless the antibiotic is washed away). The mycelium incubated with 10(-3) M cycloheximide recovers about 40% of the transport activity lost during the rapid initial phase. We have no obvious explanation for the inverse effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200128"} {"pmid": "4200129", "title": "A mathematical model for the determination of viscoelastic behavior of brain in vivo. I. Oscillatory response.", "content": "A mathematical model for the determination of viscoelastic behavior of brain in vivo. I. Oscillatory response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200129"} {"pmid": "4200130", "title": "The fracture characteristic of bone substance.", "content": "The fracture characteristic of bone substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200130"} {"pmid": "4200131", "title": "Movement and metabolism of phorate under field conditions after granular band applications.", "content": "Movement and metabolism of phorate under field conditions after granular band applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200131"} {"pmid": "4200132", "title": "Effects of physical and chemical agents on competing- and transforming-abilities of DNA in Bacillus subtilis.", "content": "Effects of physical and chemical agents on competing- and transforming-abilities of DNA in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200132"} {"pmid": "4200133", "title": "Isolation of infectious bursal disease virus and distribution of precipitating antibodies in chicken sera.", "content": "Isolation of infectious bursal disease virus and distribution of precipitating antibodies in chicken sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200133"} {"pmid": "4200136", "title": "Controlled evaluation of flurazepam hydrochloride, a new nonbarbiturate hypnotic.", "content": "Controlled evaluation of flurazepam hydrochloride, a new nonbarbiturate hypnotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200136"} {"pmid": "4200137", "title": "The current status of HAA testing at Brooke Army Medical Center. A review of two years' experience.", "content": "The current status of HAA testing at Brooke Army Medical Center. A review of two years' experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200137"} {"pmid": "4200138", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200138"} {"pmid": "4200139", "title": "Synchronized versus nonsynchronized electrocardioversion.", "content": "Synchronized versus nonsynchronized electrocardioversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200139"} {"pmid": "4200140", "title": "A study of communications between Walter Reed Army Medical Center and surrounding mental health units.", "content": "A study of communications between Walter Reed Army Medical Center and surrounding mental health units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200140"} {"pmid": "4200141", "title": "The relationship of mid-face fractures to mandibular fractures in various forms of trauma: study of 4,015 cases.", "content": "The relationship of mid-face fractures to mandibular fractures in various forms of trauma: study of 4,015 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200141"} {"pmid": "4200142", "title": "The treatment of closed head injury.", "content": "The treatment of closed head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200142"} {"pmid": "4200143", "title": "Volkmann's ischemia treated by transfibular fasciotomy.", "content": "Volkmann's ischemia treated by transfibular fasciotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200143"} {"pmid": "4200145", "title": "Some challenges for military medicine in the next decade.", "content": "Some challenges for military medicine in the next decade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200145"} {"pmid": "4200144", "title": "Vasopressin-resistant diabetes insipidus associated with short-term demethylchlortetracycline (declomycin) therapy.", "content": "Vasopressin-resistant diabetes insipidus associated with short-term demethylchlortetracycline (declomycin) therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200144"} {"pmid": "4200146", "title": "Closed injuries of the ankle.", "content": "Closed injuries of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200146"} {"pmid": "4200155", "title": "Hormonal changes in pathological pregnancy.", "content": "Hormonal changes in pathological pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200155"} {"pmid": "4200158", "title": "Inhibitory effect of antibiotic Wr-142 on synthesis of nucleic acids and proteins in B. subtilis cells.", "content": "Inhibitory effect of antibiotic Wr-142 on synthesis of nucleic acids and proteins in B. subtilis cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200158"} {"pmid": "4200161", "title": "The effect of chloramphenicol on the production of cyanophycin granule polypeptide in the blue green alga Anabaena cylindrica.", "content": "The effect of chloramphenicol on the production of cyanophycin granule polypeptide in the blue green alga Anabaena cylindrica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200161"} {"pmid": "4200150", "title": "Species and stage interaction in the feeding behaviour of vectors of Chagas disease (the importance of determinants in planning for greater efficacy and standardization of xenodiagnostic procedures).", "content": "Species and stage interaction in the feeding behaviour of vectors of Chagas disease (the importance of determinants in planning for greater efficacy and standardization of xenodiagnostic procedures).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200150"} {"pmid": "4200162", "title": "Enzymatic characterization of a phenylalanine auxotroph of the blue-green bacterium Synechococcus cedrorum.", "content": "Enzymatic characterization of a phenylalanine auxotroph of the blue-green bacterium Synechococcus cedrorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200162"} {"pmid": "4200164", "title": "Human glomerular basement membrane. Selective solubilization with chaotropes and chemical and immunologic characterization of its components.", "content": "Human glomerular basement membrane. Selective solubilization with chaotropes and chemical and immunologic characterization of its components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200164"} {"pmid": "4200165", "title": "Characterization of monkey pox virus DNA genome.", "content": "Characterization of monkey pox virus DNA genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200165"} {"pmid": "4200163", "title": "Early events in cell-animal virus interactions.", "content": "Early events in cell-animal virus interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200163"} {"pmid": "4200173", "title": "Development and application of a rapid cell sorter.", "content": "Development and application of a rapid cell sorter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200173"} {"pmid": "4200174", "title": "Quantitation of serum lipids by a simple TLC-charring method.", "content": "Quantitation of serum lipids by a simple TLC-charring method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200174"} {"pmid": "4200175", "title": "The immunoassay of thyroid-stimulating hormone and its clinical applications.", "content": "The immunoassay of thyroid-stimulating hormone and its clinical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200175"} {"pmid": "4200176", "title": "Purification and molecular properties of an unspecific carboxylesterase (E1) from rat-liver microsomes.", "content": "Purification and molecular properties of an unspecific carboxylesterase (E1) from rat-liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200176"} {"pmid": "4200177", "title": "Association-dissociation behaviour and hydrodynamic properties of apoferritin monomer and dimer.", "content": "Association-dissociation behaviour and hydrodynamic properties of apoferritin monomer and dimer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200177"} {"pmid": "4200179", "title": "Isolation of high-molecular-weight DNA from mammalian cells.", "content": "Isolation of high-molecular-weight DNA from mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200179"} {"pmid": "4200178", "title": "The synthesis and stability of ribosomal RNA in blue-green algae.", "content": "The synthesis and stability of ribosomal RNA in blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200178"} {"pmid": "4200180", "title": "Isolation and characterization of cytoplasmic L-glycerol-3-phosphate dehydrogenase from rabbit-renal-adipose tissue and its comparison with the skeletal-muscle enzyme.", "content": "Isolation and characterization of cytoplasmic L-glycerol-3-phosphate dehydrogenase from rabbit-renal-adipose tissue and its comparison with the skeletal-muscle enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200180"} {"pmid": "4200185", "title": "Resorption of amyloid and enzymatic studies in amyloidosis.", "content": "Resorption of amyloid and enzymatic studies in amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200185"} {"pmid": "4200186", "title": "Treatment of multirooted teeth with internal root resorption and perforation. Case history.", "content": "Treatment of multirooted teeth with internal root resorption and perforation. Case history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200186"} {"pmid": "4200187", "title": "How to increase the utilization and efficiency of the office laboratory for fixed prosthesis.", "content": "How to increase the utilization and efficiency of the office laboratory for fixed prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200187"} {"pmid": "4200188", "title": "Studies on the adaptation of the toad Bufo viridis to high salinities: oxygen consumption, plasma concentration and water content of the tissues.", "content": "Studies on the adaptation of the toad Bufo viridis to high salinities: oxygen consumption, plasma concentration and water content of the tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200188"} {"pmid": "4200196", "title": "Survival versus growth of a facultative psychrotroph meat and products of meat.", "content": "Survival versus growth of a facultative psychrotroph meat and products of meat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200196"} {"pmid": "4200203", "title": "The oviducts of the Egyptian cow in health and disease.", "content": "The oviducts of the Egyptian cow in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200203"} {"pmid": "4200205", "title": "A primordial bifunctional polyglucan-forming enzyme.", "content": "A primordial bifunctional polyglucan-forming enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200205"} {"pmid": "4200204", "title": "Purulent pneumococcal pericarditis. A continuing problem in the antibiotic era.", "content": "Purulent pneumococcal pericarditis. A continuing problem in the antibiotic era.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200204"} {"pmid": "4200206", "title": "An assessment of the role of parenteral alimentation in the management of surgical patients.", "content": "An assessment of the role of parenteral alimentation in the management of surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200206"} {"pmid": "4200207", "title": "Effects of saline and colloid resuscitation on renal function.", "content": "Effects of saline and colloid resuscitation on renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200207"} {"pmid": "4200208", "title": "Serotonin and central nervous system function.", "content": "Serotonin and central nervous system function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200208"} {"pmid": "4200219", "title": "Congenital goiter in four euthyroid siblings with glandular and circulating iodoproteins and defective iodothyronine synthesis.", "content": "Congenital goiter in four euthyroid siblings with glandular and circulating iodoproteins and defective iodothyronine synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200219"} {"pmid": "4200220", "title": "Gene loci for the skin and their chromosomal positions.", "content": "Gene loci for the skin and their chromosomal positions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200220"} {"pmid": "4200221", "title": "Antimicrobials. New nitrofuran derivatives.", "content": "Antimicrobials. New nitrofuran derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200221"} {"pmid": "4200222", "title": "Preparation and biological activity of various 3-deazapyrimidines and related nucleosides.", "content": "Preparation and biological activity of various 3-deazapyrimidines and related nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200222"} {"pmid": "4200225", "title": "Gonorrhoea.", "content": "Gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200225"} {"pmid": "4200230", "title": "Biological basis for high-LET radiotherapy.", "content": "Biological basis for high-LET radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200230"} {"pmid": "4200229", "title": "Aural tuberculosis in children.", "content": "Aural tuberculosis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200229"} {"pmid": "4200235", "title": "Absorption of edema following ankle fractures.", "content": "Absorption of edema following ankle fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200235"} {"pmid": "4200236", "title": "Influence of heparin-plasma, EDTA-plasma, and serum on the determination of insulin with three different radioimmunoassays.", "content": "Influence of heparin-plasma, EDTA-plasma, and serum on the determination of insulin with three different radioimmunoassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200236"} {"pmid": "4200237", "title": "Potential environmental chemical hazards. 3. Industrial and miscellaneous agents.", "content": "Potential environmental chemical hazards. 3. Industrial and miscellaneous agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200237"} {"pmid": "4200241", "title": "Serum immunoglobulin levels in five villages of the Republic of Chad and in onchocerciasis patients with and without microfilaruria.", "content": "Serum immunoglobulin levels in five villages of the Republic of Chad and in onchocerciasis patients with and without microfilaruria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200241"} {"pmid": "4200243", "title": "Suppression of Plasmodium falciparum malaria in Aotus monkeys by milk diet.", "content": "Suppression of Plasmodium falciparum malaria in Aotus monkeys by milk diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200243"} {"pmid": "4200245", "title": "Cell mediated immunity in mice innoculated with epimastigotes or trypomastigotes or Trypanosoma cruzi.", "content": "Cell mediated immunity in mice innoculated with epimastigotes or trypomastigotes or Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200245"} {"pmid": "4200247", "title": "General mechanisms of regeneration as elucidated by experiments of planarians and by a new formulation of the morphogenetic field concept.", "content": "General mechanisms of regeneration as elucidated by experiments of planarians and by a new formulation of the morphogenetic field concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200247"} {"pmid": "4200248", "title": "An atypical immunoglobulin A in benign monoclonal gammopathy.", "content": "An atypical immunoglobulin A in benign monoclonal gammopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200248"} {"pmid": "4200249", "title": "Repair processes on deoxyribonucleic acid.", "content": "Repair processes on deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200249"} {"pmid": "4200250", "title": "Toxicological problems relating to changes in the environment.", "content": "Toxicological problems relating to changes in the environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200250"} {"pmid": "4200251", "title": "Molecular structure and biosynthesis of the fatty acid synthetase-multienzyme complex of yeast.", "content": "Molecular structure and biosynthesis of the fatty acid synthetase-multienzyme complex of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200251"} {"pmid": "4200253", "title": "Studies of lipid A fractions from the lipopolysaccharides of Pseudomonas aeruginosa and Pseudomonas alcaligenes.", "content": "Studies of lipid A fractions from the lipopolysaccharides of Pseudomonas aeruginosa and Pseudomonas alcaligenes. Lipid A fractions from Pseudomonas aeruginosa and Pseudomonas alcaligenes have similar compositions and structural features. By means of hydrazinolysis of the parent lipopolysaccharides and partial hydrolysis of the deacylation products, it was established that both lipids are derived from the beta-(1-->6)-linked disaccharide of glucosamine. Phosphorylated derivatives of the disaccharide from Ps. aeruginosa were also characterized. The lipids differ mainly in the absence of hexadecanoic acid and 2-hydroxydodecanoic acid from the lipid from Ps. alcaligenes. Evidence that in Ps. aeruginosa these acids are ester-linked to residues of 3-hydroxyalkanoic acids (including 3-hydroxydecanoic acid) was obtained. Heterogeneity of lipid A fractions was indicated by t.l.c., and by gel filtration of de-O-acylation products from mild alkaline methanolysis of the lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200253"} {"pmid": "4200257", "title": "Blockage of highly-stable \"kindled\" seizures in rats by antecedent footshock.", "content": "Blockage of highly-stable \"kindled\" seizures in rats by antecedent footshock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200257"} {"pmid": "4200256", "title": "Alumina cream-induced focal motor epilepsy in cats. 2. Thickness and cellularity of cerebral cortex adjacent to epileptogenic lesions.", "content": "Alumina cream-induced focal motor epilepsy in cats. 2. Thickness and cellularity of cerebral cortex adjacent to epileptogenic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200256"} {"pmid": "4200258", "title": "Alumina cream-induced focal motor epilepsy in cats. 1. Lesion size and temporal course.", "content": "Alumina cream-induced focal motor epilepsy in cats. 1. Lesion size and temporal course.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200258"} {"pmid": "4200259", "title": "The significance of electroencephalographic paroxysms in children less than 3 years of age.", "content": "The significance of electroencephalographic paroxysms in children less than 3 years of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200259"} {"pmid": "4200260", "title": "Genetic factors in spike-wave absences.", "content": "Genetic factors in spike-wave absences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200260"} {"pmid": "4200261", "title": "Effect of trypsin and ethylenediamine tetra acetic acid on the rate of adhesion of KB cells.", "content": "Effect of trypsin and ethylenediamine tetra acetic acid on the rate of adhesion of KB cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200261"} {"pmid": "4200262", "title": "The effect of glibenclamide on non-esterified fatty acid levels in the plasma of the severely alloxan diabetic rat.", "content": "The effect of glibenclamide on non-esterified fatty acid levels in the plasma of the severely alloxan diabetic rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200262"} {"pmid": "4200264", "title": "Antibodies to venous tissue in phlebothrombosis.", "content": "Antibodies to venous tissue in phlebothrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200264"} {"pmid": "4200263", "title": "Production of lesions in various tissues by amino acids.", "content": "Production of lesions in various tissues by amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200263"} {"pmid": "4200265", "title": "A simple procedure for detecting proteins synthesized in organ cultures.", "content": "A simple procedure for detecting proteins synthesized in organ cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200265"} {"pmid": "4200266", "title": "Role of pili in the virulence of Neisseria gonorrhoeae.", "content": "Role of pili in the virulence of Neisseria gonorrhoeae. Gonococci of the colonial types that are associated with virulence, types 1 and 2, have pili that enable the bacteria both to attach in vitro to human epithelial cells and to resist phagocytosis by polymorphonuclear leukocytes. These piliated gonococci also agglutinate various mammalian and chicken erythrocytes. Gonococci of an avirulent colonial type, i.e., type 4, have no pili and neither attach to epithelial cells or erythrocytes nor resist phagocytosis. Like the type 4 bacteria, mechanically or enzymatically (trypsin) depiliated type 1 gonococci failed to attach to epithelial cells and erythrocytes and were susceptible to phagocytosis. Pili of types 1 and 2 gonococci were antigenically similar. Both type 1 gonococci and pili isolated from them induced in rabbits antibody that (i) precipitated gonococcal pili in immunodiffusion, (ii) reacted with piliated gonococci as tested by indirect immunofluorescent analysis, (iii) inhibited attachment of piliated gonococci to both human epithelial cells and erythrocytes, and (iv) opsonized piliated gonococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200266"} {"pmid": "4200268", "title": "Local cerebral blood flow in experimental middle cerebral artery vasospasm.", "content": "Local cerebral blood flow in experimental middle cerebral artery vasospasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200268"} {"pmid": "4200269", "title": "Vascular compression of the duodenum following severe brain injury. Case report.", "content": "Vascular compression of the duodenum following severe brain injury. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200269"} {"pmid": "4200271", "title": "A re-examination of stereoscopic mechanisms in area 17 of the cat.", "content": "A re-examination of stereoscopic mechanisms in area 17 of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200271"} {"pmid": "4200272", "title": "The time course of the cerebral circulatory response to metabolic depression.", "content": "The time course of the cerebral circulatory response to metabolic depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200272"} {"pmid": "4200276", "title": "The origin of life.", "content": "The origin of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200276"} {"pmid": "4200277", "title": "Molecular hysteresis and its cybernetic significance.", "content": "Molecular hysteresis and its cybernetic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200277"} {"pmid": "4200278", "title": "The cytochalasans: a new class of biologically active microbial metabolites.", "content": "The cytochalasans: a new class of biologically active microbial metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200278"} {"pmid": "4200279", "title": "Iron-sulfur proteins: structural chemistry of their chromophores and related systems.", "content": "Iron-sulfur proteins: structural chemistry of their chromophores and related systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200279"} {"pmid": "4200280", "title": "Ascending cholangitis after successful surgical repair of biliary atresia.", "content": "Ascending cholangitis after successful surgical repair of biliary atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200280"} {"pmid": "4200282", "title": "2-hydroxy-5-carbomethoxybenzyloxyamine: a new potent inhibitor of histidine decarboxylase.", "content": "2-hydroxy-5-carbomethoxybenzyloxyamine: a new potent inhibitor of histidine decarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200282"} {"pmid": "4200284", "title": "Impaired performance of delayed matching in monkeys by heptabarbitone, pentobarbitone sodium and guinalbarbitone sodium.", "content": "Impaired performance of delayed matching in monkeys by heptabarbitone, pentobarbitone sodium and guinalbarbitone sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200284"} {"pmid": "4200283", "title": "The actions of histamine on blood flow and capillary filtration coefficient (C.F.C.) in the cat small intestine.", "content": "The actions of histamine on blood flow and capillary filtration coefficient (C.F.C.) in the cat small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200283"} {"pmid": "4200289", "title": "Excretion of catecholamine metabolites following intraventricular injection of 6-hydroxydopamine in the Macaca speciosa.", "content": "Excretion of catecholamine metabolites following intraventricular injection of 6-hydroxydopamine in the Macaca speciosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200289"} {"pmid": "4200290", "title": "Evidence for multiple forms of receptors for amiloride in transporting epithelia.", "content": "Evidence for multiple forms of receptors for amiloride in transporting epithelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200290"} {"pmid": "4200291", "title": "Improved purification of rat brain choline acetyltransferase by using an immunoabsorbent.", "content": "Improved purification of rat brain choline acetyltransferase by using an immunoabsorbent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200291"} {"pmid": "4200292", "title": "Radiochemical assay of UDP glucuronyltransferase (p-nitrophenol).", "content": "Radiochemical assay of UDP glucuronyltransferase (p-nitrophenol).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200292"} {"pmid": "4200293", "title": "Cytoplasmic transfer of RNA complementary to repetitious DNA sequences during early sea urchin embryogenesis.", "content": "Cytoplasmic transfer of RNA complementary to repetitious DNA sequences during early sea urchin embryogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200293"} {"pmid": "4200286", "title": "Wildlife review. The effects of pesticides on British wildlife.", "content": "Wildlife review. The effects of pesticides on British wildlife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200286"} {"pmid": "4200287", "title": "The survival of Brucella abortus in milk and milk products.", "content": "The survival of Brucella abortus in milk and milk products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200287"} {"pmid": "4200296", "title": "Chemotherapy with hydroxyurea, leucopheresis and splenectomy in the treatment of chronic myeloid leukemia at the problastic phase.", "content": "Chemotherapy with hydroxyurea, leucopheresis and splenectomy in the treatment of chronic myeloid leukemia at the problastic phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200296"} {"pmid": "4200297", "title": "Causes and genesis of myeloid leukemia.", "content": "Causes and genesis of myeloid leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200297"} {"pmid": "4200298", "title": "Chromosome alterations in chronic myeloid leukaemia, present aspects of the problem.", "content": "Chromosome alterations in chronic myeloid leukaemia, present aspects of the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200298"} {"pmid": "4200299", "title": "Chronic myelogenous leukemia: preleukemia or leukemia?", "content": "Chronic myelogenous leukemia: preleukemia or leukemia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200299"} {"pmid": "4200300", "title": "Chronic myeloid leukaemia: advances in cytochemistry.", "content": "Chronic myeloid leukaemia: advances in cytochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200300"} {"pmid": "4200301", "title": "Cell population growth in chronic myeloid leukaemia.", "content": "Cell population growth in chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200301"} {"pmid": "4200285", "title": "Clinical problems of preventive medicine. The prevention and control of infectious ovine abortion.", "content": "Clinical problems of preventive medicine. The prevention and control of infectious ovine abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200285"} {"pmid": "4200302", "title": "Observations on the cytokinetics of chronic myeloid leukaemia.", "content": "Observations on the cytokinetics of chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200302"} {"pmid": "4200303", "title": "Blood coagulation abnormalities in chronic myeloid leukaemia.", "content": "Blood coagulation abnormalities in chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200303"} {"pmid": "4200288", "title": "Preliminary observations on a theilerial species pathogenic to cattle isolated from buffalo (Syncerus caffer) in Tanzania.", "content": "Preliminary observations on a theilerial species pathogenic to cattle isolated from buffalo (Syncerus caffer) in Tanzania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200288"} {"pmid": "4200304", "title": "Immune reactions in chronic myeloid leukaemia.", "content": "Immune reactions in chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200304"} {"pmid": "4200305", "title": "Studies on the genesis of anemia in chronic myeloid leukaemia--in vitro response of bone marrow cells to erythropoietin.", "content": "Studies on the genesis of anemia in chronic myeloid leukaemia--in vitro response of bone marrow cells to erythropoietin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200305"} {"pmid": "4200306", "title": "A comparative essay of drugs in the treatment of chronic myeloid leukaemia.", "content": "A comparative essay of drugs in the treatment of chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200306"} {"pmid": "4200307", "title": "Clinical pharmacology of dibromohexitols.", "content": "Clinical pharmacology of dibromohexitols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200307"} {"pmid": "4200308", "title": "Dibromomannitol and chronic myeloid leukaemia results of a cooperative study.", "content": "Dibromomannitol and chronic myeloid leukaemia results of a cooperative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200308"} {"pmid": "4200309", "title": "New trends in the management of chronic myeloid leukaemia.", "content": "New trends in the management of chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200309"} {"pmid": "4200310", "title": "Treatment of the blastic phase of chronic myeloid leukaemia. A question to solve.", "content": "Treatment of the blastic phase of chronic myeloid leukaemia. A question to solve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200310"} {"pmid": "4200311", "title": "Therapeutic experiences in chronic granulocytic leukaemia.", "content": "Therapeutic experiences in chronic granulocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200311"} {"pmid": "4200312", "title": "Chronic myeloid leukaemia: course, life expectancy, and an analysis of dibromomannitol and busulfan treatment.", "content": "Chronic myeloid leukaemia: course, life expectancy, and an analysis of dibromomannitol and busulfan treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200312"} {"pmid": "4200313", "title": "Therapeutic effect of the removal of leukocytes by cell separator.", "content": "Therapeutic effect of the removal of leukocytes by cell separator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200313"} {"pmid": "4200314", "title": "Results in the treatment of chronic myeloid leukaemia.", "content": "Results in the treatment of chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200314"} {"pmid": "4200316", "title": "The affinity of mycobacterial glycopetides for guinea-pig gamma immunoglobulin and its fragments.", "content": "The affinity of mycobacterial glycopetides for guinea-pig gamma immunoglobulin and its fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200316"} {"pmid": "4200318", "title": "Conglutinating activity in apparently healthy human and animal sera.", "content": "Conglutinating activity in apparently healthy human and animal sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200318"} {"pmid": "4200317", "title": "Cellular immunity in experimental glomerulonephritis of rats. II. A sequential study of immunological events occurring during development of the disease.", "content": "Cellular immunity in experimental glomerulonephritis of rats. II. A sequential study of immunological events occurring during development of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200317"} {"pmid": "4200319", "title": "Purification and characterization of cytochrome b5-like hemoprotein associated with outer mitochondrial membrane of rat liver.", "content": "Purification and characterization of cytochrome b5-like hemoprotein associated with outer mitochondrial membrane of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200319"} {"pmid": "4200321", "title": "The potential use of high-performance liquid chromatography in residue analysis.", "content": "The potential use of high-performance liquid chromatography in residue analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200321"} {"pmid": "4200320", "title": "Studies on ribosomal ribonucleic acid from yeast. I. Isolation and characterization of anomalous heavier 30 S robonucleic acid.", "content": "Studies on ribosomal ribonucleic acid from yeast. I. Isolation and characterization of anomalous heavier 30 S robonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200320"} {"pmid": "4200322", "title": "An enzyme preparation inactivating all penicillins and cephalosporins.", "content": "An enzyme preparation inactivating all penicillins and cephalosporins. Commercial penicillinases vary in their capacity to destroy penicillinase-resistant penicillins and cephalosporins. A new freeze-dried preparation containing both beta-lactamase I and II was found to inactivate all penicillins and cephalosporins at levels above those likely to be encountered in clinical specimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200322"} {"pmid": "4200323", "title": "An outbreak of diphtheria in a hospital for the mentally subnormal.", "content": "An outbreak of diphtheria in a hospital for the mentally subnormal. An account is given of two separate outbreaks of diphtheria amongst mentally subnormal patients and nursing staff. In a total hospital population of about 1000 the number of people involved as carriers or cases was 60 and there were five deaths. The 60 people comprised 56 patients, of whom four were involved in both outbreaks, and four nurses. The organisms isolated were C. diphtheriae mitis but five strains were non-toxigenic. It is postulated that the outbreak began following the conversion of a non-toxigenic organism to a toxigenic one by bacteriophage action. The fatal cases were examples of membranous pharyngo-laryngo-tracheo-bronchial diphtheria with well marked pseudo-casts of the upper air passages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200323"} {"pmid": "4200324", "title": "Experimental hypercalcaemia and whole blood clotting.", "content": "Experimental hypercalcaemia and whole blood clotting. Experimental hypercalcaemia was induced in rats by (1) transplantation of the solid Walker 256 tumour, and (2) intraperitoneal injections of calcium gluconate. Whole blood clotting was studied by means of thromboelastography and whole blood clotting times in polystyrene and glass test tubes. At serum calcium levels between 10.3 and 11.5 m-equiv/l a slight delay in clot formation was found which was reversible by the addition of EDTA to whole blood. Acute, calcium-gluconate-induced hypercalcaemia, however, leads to a significant shortening of the clotting time in the polystyrene tube and to a lesser degree in the glass tube. Maximal factor XII activation in vitro with ellagic acid levels the difference of clotting times again. From these experiments it is concluded that acute hypercalcaemia induces a hypercoagulable state, possibly by partial contact activation, and thus may favour thrombus formation in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200324"} {"pmid": "4200325", "title": "The enterohepatic circulation of bile acids as they relate to lipid disorders.", "content": "The enterohepatic circulation of bile acids as they relate to lipid disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200325"} {"pmid": "4200326", "title": "Measurement of myocardial blood flow by means of external counting method using 86-rubidium.", "content": "Measurement of myocardial blood flow by means of external counting method using 86-rubidium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200326"} {"pmid": "4200327", "title": "The catalytic mechanism of carbonic anhydrase.", "content": "The catalytic mechanism of carbonic anhydrase. It is shown that an \"inverse\" relationship between the pH dependencies of the rates of hydration of CO(2) and dehydration of HCO(3) (-) by carbonic anhydrase (EC 4.2.1.1) is a direct consequence of the thermodynamic equilibrium between CO(2) and HCO(3) (-) and independent of any assumptions about the catalytic mechanism. It is further shown that proposed mechanisms for carbonic anhydrase involving HCO(3) (-) as the substrate in the dehydration reaction and a proton transfer reaction, EH(+) right harpoon over left harpoon E + H(+), as an obligatory step during catalysis obey the rule of microscopic reversibility. This includes mechanisms in which the proton dissociation is from a zinc-coordinated water molecule. Such mechanisms can be in accord with the observed rapid turnover rates of the enzyme, since rapid proton exchange can occur with the buffer components, EH(+) + B right harpoon over left harpoon E + BH(+). Mechanisms in which H(2)CO(3) is the substrate in dehydration avoid the proton-transfer step, but require that H(2)CO(3) combines with enzyme more rapidly than in a diffusion-controlled reaction. Physico-chemical evidence for and against a zinc-hydroxide mechanism is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200327"} {"pmid": "4200328", "title": "Metabolic demands after surgery.", "content": "Metabolic demands after surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200328"} {"pmid": "4200329", "title": "Intravenous nutrition: the materials available.", "content": "Intravenous nutrition: the materials available.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200329"} {"pmid": "4200330", "title": "Management of prolonged intravenous feeding.", "content": "Management of prolonged intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200330"} {"pmid": "4200331", "title": "Epidemiology of Chagas' disease and methods of detecting T. cruzi.", "content": "Epidemiology of Chagas' disease and methods of detecting T. cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200331"} {"pmid": "4200332", "title": "Immunology in cutaneous leishmaniasis.", "content": "Immunology in cutaneous leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200332"} {"pmid": "4200333", "title": "Transmission of hepatitis and Australia antigenaemia within a liver unit.", "content": "Transmission of hepatitis and Australia antigenaemia within a liver unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200333"} {"pmid": "4200334", "title": "Caffeine contractures in depolarized heart muscle.", "content": "Caffeine contractures in depolarized heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200334"} {"pmid": "4200335", "title": "Clinical hypersensitivity states and serum protein modifications.", "content": "Clinical hypersensitivity states and serum protein modifications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200335"} {"pmid": "4200346", "title": "Coagulation of hyperglobulinaemic mink blood by glutaraldehyde.", "content": "Coagulation of hyperglobulinaemic mink blood by glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200346"} {"pmid": "4200349", "title": "Response to selection in synthetic lines of Drosophila melanogaster.", "content": "Response to selection in synthetic lines of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200349"} {"pmid": "4200348", "title": "Right-sided bacterial endocarditis. New concepts in the treatment of the uncontrollable infection.", "content": "Right-sided bacterial endocarditis. New concepts in the treatment of the uncontrollable infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200348"} {"pmid": "4200350", "title": "The respiratory chain of Azotobacter vinelandii. I. Spectral properites of cytochrome d.", "content": "The respiratory chain of Azotobacter vinelandii. I. Spectral properites of cytochrome d.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200350"} {"pmid": "4200351", "title": "Feedback controlling oxygen production in a cross-reaction between two photosystems in photosynthesis.", "content": "Feedback controlling oxygen production in a cross-reaction between two photosystems in photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200351"} {"pmid": "4200352", "title": "The turnover times of photosynthesis and redox properties of the pool of electron carriers between the photosystems.", "content": "The turnover times of photosynthesis and redox properties of the pool of electron carriers between the photosystems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200352"} {"pmid": "4200353", "title": "The formation of pyrimidine dimers in the DNA of fungi and bacteria.", "content": "The formation of pyrimidine dimers in the DNA of fungi and bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200353"} {"pmid": "4200354", "title": "The management of radiation caries.", "content": "The management of radiation caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200354"} {"pmid": "4200355", "title": "An investigation into the spread of bacterial infection in lower-limb amputations.", "content": "An investigation into the spread of bacterial infection in lower-limb amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200355"} {"pmid": "4200356", "title": "Silver phosphanilamidopyrimidine. A new silver sulfadiazine analogue effective against Pseudomonas infection in burned mice.", "content": "Silver phosphanilamidopyrimidine. A new silver sulfadiazine analogue effective against Pseudomonas infection in burned mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200356"} {"pmid": "4200363", "title": "Cortical projection of group I muscle afferents to areas 2, 3a, and the vestibular field in the rhesus monkey.", "content": "Cortical projection of group I muscle afferents to areas 2, 3a, and the vestibular field in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200363"} {"pmid": "4200364", "title": "Observations on the rates of ion movement and hypercapnia in aqueous humor.", "content": "Observations on the rates of ion movement and hypercapnia in aqueous humor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200364"} {"pmid": "4200365", "title": "Purification of the human complement protein C1q by affinity chromatography.", "content": "Purification of the human complement protein C1q by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200365"} {"pmid": "4200366", "title": "Expression of the a, x, and y variable region genes of heavy chains among IgG, IgM, and IgA molecules of normal and a locus allotype-suppressed rabbits.", "content": "Expression of the a, x, and y variable region genes of heavy chains among IgG, IgM, and IgA molecules of normal and a locus allotype-suppressed rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200366"} {"pmid": "4200368", "title": "Antigenicity of formaldehyde-inactivated staphylococcal enterotoxin B.", "content": "Antigenicity of formaldehyde-inactivated staphylococcal enterotoxin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200368"} {"pmid": "4200367", "title": "Detection of idiotypic determinants on human monoclonal proteins with specific rabbit antisera and hemagglutination-inhibition.", "content": "Detection of idiotypic determinants on human monoclonal proteins with specific rabbit antisera and hemagglutination-inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200367"} {"pmid": "4200369", "title": "Perimenstrual aggression in groups of female rhesus monkeys.", "content": "Perimenstrual aggression in groups of female rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200369"} {"pmid": "4200374", "title": "The influence of the nucleolar organizer region on sperm utilization in Drosophila melanogaster.", "content": "The influence of the nucleolar organizer region on sperm utilization in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200374"} {"pmid": "4200375", "title": "Asymmetric transcription of SPP1 in vivo.", "content": "Asymmetric transcription of SPP1 in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200375"} {"pmid": "4200377", "title": "Dietary data and estimates of energy expenditure.", "content": "Dietary data and estimates of energy expenditure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200377"} {"pmid": "4200380", "title": "The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey.", "content": "The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200380"} {"pmid": "4200381", "title": "Radiotherapy in the treatment of osteoarthrosis of the knee.", "content": "Radiotherapy in the treatment of osteoarthrosis of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200381"} {"pmid": "4200382", "title": "Respiratory disease in cork workers (\"suberosis\").", "content": "Respiratory disease in cork workers (\"suberosis\").", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200382"} {"pmid": "4200384", "title": "Light and electron microscopy of parathyroid carcinoma. Report of three cases.", "content": "Light and electron microscopy of parathyroid carcinoma. Report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200384"} {"pmid": "4200386", "title": "Ectopical decidua formation in the ovary (so-called deciduoma).", "content": "Ectopical decidua formation in the ovary (so-called deciduoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200386"} {"pmid": "4200387", "title": "Repair in arterial tissue. A scanning electron microscopic (SEM) and light microscopic study on the endothelium of rabbit thoracic aorta following a single dilatation injury.", "content": "Repair in arterial tissue. A scanning electron microscopic (SEM) and light microscopic study on the endothelium of rabbit thoracic aorta following a single dilatation injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200387"} {"pmid": "4200389", "title": "Lateral pterygoid: two muscles?", "content": "Lateral pterygoid: two muscles?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200389"} {"pmid": "4200390", "title": "Neurohistological observations on the heart of the Indian rhesus monkey, Macaca rhesus.", "content": "Neurohistological observations on the heart of the Indian rhesus monkey, Macaca rhesus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200390"} {"pmid": "4200391", "title": "Lymphoid cells converted by lymphoid RNA extracts in vitro and in vivo to synthesize allogeneic immunoglobulins.", "content": "Lymphoid cells converted by lymphoid RNA extracts in vitro and in vivo to synthesize allogeneic immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200391"} {"pmid": "4200392", "title": "Interspecies \"transfer\" of delayed hypersensitivity in vitro with RNA extracts.", "content": "Interspecies \"transfer\" of delayed hypersensitivity in vitro with RNA extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200392"} {"pmid": "4200393", "title": "Lactase-phlorizin hydrolase complex from monkey small intestine: stimulation of phlorizin hydrolase activity by organic acids.", "content": "Lactase-phlorizin hydrolase complex from monkey small intestine: stimulation of phlorizin hydrolase activity by organic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200393"} {"pmid": "4200394", "title": "The use of glutaraldehyde fixation to analyze the mechanism of factor catalyzed reassociation of eukaryotic ribosomal subunits.", "content": "The use of glutaraldehyde fixation to analyze the mechanism of factor catalyzed reassociation of eukaryotic ribosomal subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200394"} {"pmid": "4200395", "title": "Dissociation of eukaryotic ribosomes by purified initiation factor EIF-3.", "content": "Dissociation of eukaryotic ribosomes by purified initiation factor EIF-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200395"} {"pmid": "4200396", "title": "Isolation of carcinogenic aminoazo dye-binding protein and its identification as alcohol dehydrogenase.", "content": "Isolation of carcinogenic aminoazo dye-binding protein and its identification as alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200396"} {"pmid": "4200398", "title": "Multiple DNA polymerase activity solubilized from higher plant chromatin.", "content": "Multiple DNA polymerase activity solubilized from higher plant chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200398"} {"pmid": "4200388", "title": "Are interoceptive stimuli sufficient for instrumental conditioning?", "content": "Are interoceptive stimuli sufficient for instrumental conditioning?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200388"} {"pmid": "4200397", "title": "Affinity chromatography of thermolysin and of neutral proteases from B. subtilis.", "content": "Affinity chromatography of thermolysin and of neutral proteases from B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200397"} {"pmid": "4200399", "title": "Nucleus-associated RNA in measles virus-infected cells.", "content": "Nucleus-associated RNA in measles virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200399"} {"pmid": "4200400", "title": "Atomic coordinates for ferricytochrome c2 of Rhodospirillum rubrum.", "content": "Atomic coordinates for ferricytochrome c2 of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200400"} {"pmid": "4200402", "title": "Detection of biliary tract disease at operation.", "content": "Detection of biliary tract disease at operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200402"} {"pmid": "4200401", "title": "The influence of sodium, potassium and lithium on the response of glycogen synthetase I to insulin and epinephrine in the isolated rat diaphragm.", "content": "The influence of sodium, potassium and lithium on the response of glycogen synthetase I to insulin and epinephrine in the isolated rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200401"} {"pmid": "4200403", "title": "Prepacked milk feeds for continuous intragastric feeding.", "content": "Prepacked milk feeds for continuous intragastric feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200403"} {"pmid": "4200405", "title": "Cryopreservation of infective particles of Theileria parva.", "content": "Cryopreservation of infective particles of Theileria parva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200405"} {"pmid": "4200406", "title": "The bacteriochlorophyll absorption band shifts linked with the energy state of photosynthetic bacteria membranes.", "content": "The bacteriochlorophyll absorption band shifts linked with the energy state of photosynthetic bacteria membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200406"} {"pmid": "4200407", "title": "Electron microscopy of incontinentia pigmenti.", "content": "Electron microscopy of incontinentia pigmenti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200407"} {"pmid": "4200408", "title": "Kinetics of the two-sited enzyme. II. A method of distinguishing between anticooperative and independent active sites based on competitive inhibition.", "content": "Kinetics of the two-sited enzyme. II. A method of distinguishing between anticooperative and independent active sites based on competitive inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200408"} {"pmid": "4200409", "title": "Borna disease (BD), a slow virus infection. Biological properties of the virus.", "content": "Borna disease (BD), a slow virus infection. Biological properties of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200409"} {"pmid": "4200412", "title": "Electron microscopy of intimal plaques following induction of large superficial mechanical injury (transverse injury) in the rabbit aorta.", "content": "Electron microscopy of intimal plaques following induction of large superficial mechanical injury (transverse injury) in the rabbit aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200412"} {"pmid": "4200413", "title": "Comparative microspectrophotometric study of the DNA content in the diagnosis of pre-tumorous processes and cancer.", "content": "Comparative microspectrophotometric study of the DNA content in the diagnosis of pre-tumorous processes and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200413"} {"pmid": "4200414", "title": "On the presence of a concanavalin-A reactive coat over the endothelial aortic surface and its modifications during early experimental cholesterol atherogenesis in rabbits.", "content": "On the presence of a concanavalin-A reactive coat over the endothelial aortic surface and its modifications during early experimental cholesterol atherogenesis in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200414"} {"pmid": "4200415", "title": "Cytoplasmic fusions between liver parenchymal cells and infiltrating cells in chronic aggressive hepatitis.", "content": "Cytoplasmic fusions between liver parenchymal cells and infiltrating cells in chronic aggressive hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200415"} {"pmid": "4200421", "title": "Cytogenetic studies in protein-calorie malnutrition.", "content": "Cytogenetic studies in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200421"} {"pmid": "4200422", "title": "Combining intra-abdominal arterial grafting with gastrointestinal or biliary tract procedures.", "content": "Combining intra-abdominal arterial grafting with gastrointestinal or biliary tract procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200422"} {"pmid": "4200423", "title": "Intrajejunal administration of an elemental diet at neutral pH avoids pancreatic stimulation. Studies in dog and man.", "content": "Intrajejunal administration of an elemental diet at neutral pH avoids pancreatic stimulation. Studies in dog and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200423"} {"pmid": "4200424", "title": "Parenteral alimentation in infants and children with life-threatening illness.", "content": "Parenteral alimentation in infants and children with life-threatening illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200424"} {"pmid": "4200425", "title": "Selective inhibition of phagocytic activity of rabbit alveolar macrophages by cystic fibrosis serum.", "content": "Selective inhibition of phagocytic activity of rabbit alveolar macrophages by cystic fibrosis serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200425"} {"pmid": "4200426", "title": "Computer files and analyses of laboratory data from tuberculosis patients.", "content": "Computer files and analyses of laboratory data from tuberculosis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200426"} {"pmid": "4200427", "title": "Serum alpha 1-antitrypsin variants. Prevalence and clinical spirometry.", "content": "Serum alpha 1-antitrypsin variants. Prevalence and clinical spirometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200427"} {"pmid": "4200428", "title": "Glomerular changes in acute plasmodium falciparum infection. An immunopathologic study.", "content": "Glomerular changes in acute plasmodium falciparum infection. An immunopathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200428"} {"pmid": "4200429", "title": "Organ-specific differences in the methylation of transfer RNA in vitro.", "content": "Organ-specific differences in the methylation of transfer RNA in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200429"} {"pmid": "4200431", "title": "Radioassay of serum folate.", "content": "Radioassay of serum folate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200431"} {"pmid": "4200430", "title": "Oxidative activation of benz(a)anthracene and methylated derivatives in mutagenesis and carcinogenesis.", "content": "Oxidative activation of benz(a)anthracene and methylated derivatives in mutagenesis and carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200430"} {"pmid": "4200433", "title": "Scanning electron microscopy of human, monkey, and rabbit spermatozoa.", "content": "Scanning electron microscopy of human, monkey, and rabbit spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200433"} {"pmid": "4200432", "title": "Monkey ovarian contractility--its relationship to ovulation.", "content": "Monkey ovarian contractility--its relationship to ovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200432"} {"pmid": "4200434", "title": "Copper levels in tissues of rhesus monkeys bearing intrauterine or intra-abdominal copper devices.", "content": "Copper levels in tissues of rhesus monkeys bearing intrauterine or intra-abdominal copper devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200434"} {"pmid": "4200437", "title": "Fertility of abnormal hemoglobin carriers in Porto Alegre, Brazil.", "content": "Fertility of abnormal hemoglobin carriers in Porto Alegre, Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200437"} {"pmid": "4200438", "title": "Blood groups, secretor status and ability to taste phenylthiocarbamide in some Muslim groups.", "content": "Blood groups, secretor status and ability to taste phenylthiocarbamide in some Muslim groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200438"} {"pmid": "4200439", "title": "Immunoglobulin characteristics of antibodies to malarial S-antigens in man.", "content": "Immunoglobulin characteristics of antibodies to malarial S-antigens in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200439"} {"pmid": "4200441", "title": "Oculomotor defects in cerebellectomized monkeys.", "content": "Oculomotor defects in cerebellectomized monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200441"} {"pmid": "4200440", "title": "Structural changes in sheep antibody induced by interaction with polypeptide antigens.", "content": "Structural changes in sheep antibody induced by interaction with polypeptide antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200440"} {"pmid": "4200442", "title": "Letter: Oculomotor control system.", "content": "Letter: Oculomotor control system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200442"} {"pmid": "4200443", "title": "The phagolysosomal system of the pigment epithelium. A key to retinal disease.", "content": "The phagolysosomal system of the pigment epithelium. A key to retinal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200443"} {"pmid": "4200444", "title": "Platelet-induced vitreous membrane formation.", "content": "Platelet-induced vitreous membrane formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200444"} {"pmid": "4200445", "title": "Laser trabeculotomy in monkeys.", "content": "Laser trabeculotomy in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200445"} {"pmid": "4200446", "title": "Yersinia pseudotuberculosis infection in a Siberian tiger and a spider monkey.", "content": "Yersinia pseudotuberculosis infection in a Siberian tiger and a spider monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200446"} {"pmid": "4200447", "title": "Undifferentiated salivary gland carcinoma in a baboon.", "content": "Undifferentiated salivary gland carcinoma in a baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200447"} {"pmid": "4200448", "title": "Renal carcinoma in a rhesus monkey.", "content": "Renal carcinoma in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200448"} {"pmid": "4200449", "title": "Intraocular echinococcosis in a rhesus monkey.", "content": "Intraocular echinococcosis in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200449"} {"pmid": "4200450", "title": "Indirect inguinal hernia in two baboons.", "content": "Indirect inguinal hernia in two baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200450"} {"pmid": "4200451", "title": "Dermatophilosis (cutaneous streptothricosis) in owl monkeys.", "content": "Dermatophilosis (cutaneous streptothricosis) in owl monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200451"} {"pmid": "4200452", "title": "Pesticide effect on rumen microbial function.", "content": "Pesticide effect on rumen microbial function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200452"} {"pmid": "4200453", "title": "Destruction of psychrophilic strains of Bacillus by chlorine.", "content": "Destruction of psychrophilic strains of Bacillus by chlorine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200453"} {"pmid": "4200454", "title": "Immunochemical and immunofluorescence studies of beta-trace protein in different species and organs, with special reference to the central nervous system.", "content": "Immunochemical and immunofluorescence studies of beta-trace protein in different species and organs, with special reference to the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200454"} {"pmid": "4200455", "title": "Ultraviolet absorption characteristics of myelin from the central nervous system.", "content": "Ultraviolet absorption characteristics of myelin from the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200455"} {"pmid": "4200456", "title": "Inflammatory changes in the non-infected prostate gland. A clinical, microbiological and histological investigation.", "content": "Inflammatory changes in the non-infected prostate gland. A clinical, microbiological and histological investigation. 36 patients (18 with chronic prostatitis and 18 with chronic urethritis) were studied to determine the incidence and nature of prostatic inflammatory changes in patients with clinically diagnosed chronic prostatitis and chronic urethritis without the occurrence of aerobic and anaerobic bacteria, Mycoplasms, and fungi or viruses in the prostatic tissue or prostatic secretion. Excretory urography (IVP), cytoscopy and urethroscopy were performed on all patients. Prostatic biopsy was done transperineally by the method of Veenema. None of the biopsy specimens exhibited acute inflammatory changes. Chronic inflammation in the form of infiltration around the acini with mononuclear inflammatory cells occurred without simultaneous infection in 17 cases. Changes were slight in 11 cases, moderate in 5 and severe in 1. No relationship was found between changes in the appearance of epithelium and occurrence of inflammatory changes. Causes of inflammatory reaction is not known. Current research is being done to determine possible cell-bound hypersensitivity using lymphocyte migration technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200456"} {"pmid": "4200457", "title": "Unilateral diverticulum of the ureter: a case report and scanning electron microscopic study.", "content": "Unilateral diverticulum of the ureter: a case report and scanning electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200457"} {"pmid": "4200458", "title": "Letter: RH sensitization associated with drug use.", "content": "Letter: RH sensitization associated with drug use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200458"} {"pmid": "4200459", "title": "Letter: Mechanism of host specificity in malarial infection.", "content": "Letter: Mechanism of host specificity in malarial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200459"} {"pmid": "4200460", "title": "Human x mouse somatic cell hybrid clone secreting immunoglobulins of both parental types.", "content": "Human x mouse somatic cell hybrid clone secreting immunoglobulins of both parental types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200460"} {"pmid": "4200461", "title": "Transplantation of isolated pancreatic islets into the portal vein of diabetic rats.", "content": "Transplantation of isolated pancreatic islets into the portal vein of diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200461"} {"pmid": "4200462", "title": "Cursive epilepsy and gelastic epilepsy.", "content": "Cursive epilepsy and gelastic epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200462"} {"pmid": "4200465", "title": "Antiepileptic therapy and rickets in children.", "content": "Antiepileptic therapy and rickets in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200465"} {"pmid": "4200466", "title": "Applications of the electron beam in the treatment of cancer of the skin and lips.", "content": "Applications of the electron beam in the treatment of cancer of the skin and lips.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200466"} {"pmid": "4200467", "title": "Relative surface doses from supervoltage radiation.", "content": "Relative surface doses from supervoltage radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200467"} {"pmid": "4200468", "title": "Lung corrections for 8-MV X rays.", "content": "Lung corrections for 8-MV X rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200468"} {"pmid": "4200470", "title": "Localization and content of thyrotrophin releasing factor (TRE) in median eminence of the hypothalamus.", "content": "Localization and content of thyrotrophin releasing factor (TRE) in median eminence of the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200470"} {"pmid": "4200472", "title": "Peripheral plasma levels of oestrogens, progesterone and 17alpha-hydroxyprogesterone during gestation in the rhesus monkey.", "content": "Peripheral plasma levels of oestrogens, progesterone and 17alpha-hydroxyprogesterone during gestation in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200472"} {"pmid": "4200471", "title": "Peripheral plasma levels of oestrogen and progesterone in pregnant rhesus monkeys treated with dexamethasone.", "content": "Peripheral plasma levels of oestrogen and progesterone in pregnant rhesus monkeys treated with dexamethasone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200471"} {"pmid": "4200474", "title": "Concordance of radioassay and microbiological assay in the study of the ethanol-induced fall in serum folate level.", "content": "Concordance of radioassay and microbiological assay in the study of the ethanol-induced fall in serum folate level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200474"} {"pmid": "4200476", "title": "Anticomplementary hepatitis B antigen. Prognostic importance in chronic active liver disease.", "content": "Anticomplementary hepatitis B antigen. Prognostic importance in chronic active liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200476"} {"pmid": "4200475", "title": "Peripheral control of hormone metabolism.", "content": "Peripheral control of hormone metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200475"} {"pmid": "4200477", "title": "Protection with split and whole virus vaccines against influenza.", "content": "Protection with split and whole virus vaccines against influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200477"} {"pmid": "4200479", "title": "Letter: Pathogenesis of measles.", "content": "Letter: Pathogenesis of measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200479"} {"pmid": "4200478", "title": "Plasma C3 and C4 concentrations in management of glomerulonephritis.", "content": "Plasma C3 and C4 concentrations in management of glomerulonephritis. As part of a larger study of serial complement profiles in glomerulonephritis plasma C3 and C4 concentrations were measured using commercially available immunodiffusion plates. A total of 303 samples were obtained from 128 patients suffering from forms of nephritis associated with hypocomplementaemia-namely, lupus nephritis, mesangiocapillary glomerulonephritis (M.C.G.N.), and acute glomerulonephritis.These simple measurements of C3 and C4 gave clinically useful information. In lupus nephritis C3 and C4 generally correlated and C4 concentrations were more often and more profoundly depressed than C3 concentrations. Neither C3 nor C4 concentrations alone correlated well with the antinuclear factor titre.In both acute glomerulonephritis and M.C.G.N. the C3 concentrations were frequently lower than 20% of normal (which was never the case in patients with lupus), while the C4 concentration was usually normal and was almost never depressed in the absence of C3 depression. This suggests activation of complement at the C3 level by the \"bypass\" pathway in acute nephritis as well as in M.C.G.N., though both may be operating in some patients. In acute glomerulonephritis but not in M.C.G.N. C3 concentrations returned to normal within eight to 12 weeks.The two varieties of M.C.G.N. identified by the site of the deposits in the capillary glomerular walls differed in their C3 levels. In 10 patients with intramembranous dense linear deposits the C3 was always low over very long periods of time, rising in three out of four patients only after transplantation and immunosuppression. Other patients with M.C.G.N., in contrast, often showed normal C3 concentrations. Concentrations of C4 did not differ in either group, being normal in 80% of samples from all types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200478"} {"pmid": "4200480", "title": "Letter: Prepacked milk feeds for continuous intragastric feeding.", "content": "Letter: Prepacked milk feeds for continuous intragastric feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200480"} {"pmid": "4200482", "title": "Study on Saskatchewan community clinics suggests total health expenditure not less.", "content": "Study on Saskatchewan community clinics suggests total health expenditure not less.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200482"} {"pmid": "4200483", "title": "Study on Saskatchewan community clinics suggests total health expenditure not less. Report's data and interpretation suspect.", "content": "Study on Saskatchewan community clinics suggests total health expenditure not less. Report's data and interpretation suspect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200483"} {"pmid": "4200481", "title": "Resistance of Pseudomonas aeruginosa to gentamicin.", "content": "Resistance of Pseudomonas aeruginosa to gentamicin. The resistance to gentamicin 4 mug./ml. of 250 Pseudomonas aeruginosa isolates was measured by a proportion method. Twenty-eight (11.2%) of the cultures fell into the most resistant group, in whose populations between 10 and 100% of the organisms were resistant. A relatively high percentage of urinary isolates and a comparatively low percentage of isolates from respiratory sources occurred in this group. Three of the 28 were resistant to carbenicillin 150 mug./ml. and 6 of 18 tested were as resistant to gentamicin 8 mug./ml. as they were to 4 mug./ml. The distribution of Ps. aeruginosa isolates between the different grades of resistance did not change significantly during the 10 months in which the survey was performed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200481"} {"pmid": "4200484", "title": "Study on Saskatchewan community clinics suggests total health expenditure not less. Report fails to deal with incentive issue for clinics physicians.", "content": "Study on Saskatchewan community clinics suggests total health expenditure not less. Report fails to deal with incentive issue for clinics physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200484"} {"pmid": "4200485", "title": "Pharmacologic studies of camptothecin (NSC-100880): distribution, plasma protein binding, and biliary excretion.", "content": "Pharmacologic studies of camptothecin (NSC-100880): distribution, plasma protein binding, and biliary excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200485"} {"pmid": "4200486", "title": "A new antitumor antimetabolite, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): antimicrobial reversal studies and preliminary evaluation against L1210 mouse leukemia in vivo.", "content": "A new antitumor antimetabolite, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): antimicrobial reversal studies and preliminary evaluation against L1210 mouse leukemia in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200486"} {"pmid": "4200487", "title": "Motor behaviors of neonatal rhesus monkeys: measurement techniques and early development.", "content": "Motor behaviors of neonatal rhesus monkeys: measurement techniques and early development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200487"} {"pmid": "4200488", "title": "Reversal learning in the neonatal rhesus monkey.", "content": "Reversal learning in the neonatal rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200488"} {"pmid": "4200489", "title": "Mother-infant separation in squirrel monkeys living in a group.", "content": "Mother-infant separation in squirrel monkeys living in a group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200489"} {"pmid": "4200495", "title": "Plasma thyrotropin response to thyrotropin-releasing hormone in patients with pituitary and hypothalamic disorders.", "content": "Plasma thyrotropin response to thyrotropin-releasing hormone in patients with pituitary and hypothalamic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200495"} {"pmid": "4200498", "title": "Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to carbon dioxide.", "content": "Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to carbon dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200498"} {"pmid": "4200499", "title": "Immunization of female baboons with hapten-coupled gonadotropins.", "content": "Immunization of female baboons with hapten-coupled gonadotropins. Female baboons (papio anubis) were immunized with gonadotropin preparations that had been structurally altered by hapten-coupling and the effects of such immunizations upon the events of the menstrual cycle were observed. Antibodies were detected against the immunizing antigen within 3-5 weeks. Cross-reaction of antibodies to sulphanil-azo-human luteinizing hormone (LH), human chorionic gonadotropin and ovine LH with unaltered baboon LH was marked only during the first 8 weeks, the period of immunoglobulin M (IgM) abundance, then dropped sharply as the antisera shifted to nearly all IgG. This drop did not occur with monkey and baboon immunizations. Ovulation was disrupted for 2-3 months with human and ovine gonadotropin immunizations but sulphanil-azo-monkey or baboon LH caused anovulation for 4-8 months. A reduction of hormone secretion correlated with titers of cross-reactivity. This evidence suggested that hapten-coupling produced changes in gonadotropins with enhance their antigenicity and the cross-reactivity of antibodies raised to them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200499"} {"pmid": "4200500", "title": "Plasma thyrotropin and its response to thyrotropin releasing hormone in normal pregnancy.", "content": "Plasma thyrotropin and its response to thyrotropin releasing hormone in normal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200500"} {"pmid": "4200501", "title": "Immunobiological entity of human leukemia reproduced in cayman.", "content": "Immunobiological entity of human leukemia reproduced in cayman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200501"} {"pmid": "4200502", "title": "Drinking as an avoidance response by the pigtail monkey (Macaca nemestrina).", "content": "Drinking as an avoidance response by the pigtail monkey (Macaca nemestrina).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200502"} {"pmid": "4200506", "title": "Delayed recovery of function following orbital prefrontal lesions in infant monkeys.", "content": "Delayed recovery of function following orbital prefrontal lesions in infant monkeys. Monkeys given orbital prefrontal lesions at 1, 4, or 8 weeks of age exhibited a severe learning disability when they were tested at 1 year of age, but showed substantial recovery by the time they were 2 years old. These results suggest that the protracted maturation of intact cortical regions is important in recovery of function after early brain injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200506"} {"pmid": "4200507", "title": "Letter: Carbon dioxide and pH: effect on species succession of algae.", "content": "Letter: Carbon dioxide and pH: effect on species succession of algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200507"} {"pmid": "4200511", "title": "The completion cholangiogram: failure to empty due to pseudo-obstruction.", "content": "The completion cholangiogram: failure to empty due to pseudo-obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200511"} {"pmid": "4200512", "title": "Preoperative preparation of the colon with an elemental diet.", "content": "Preoperative preparation of the colon with an elemental diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200512"} {"pmid": "4200513", "title": "Temperature-sensitive mutants of toxinogenic corynebacteriophage beta. I. Genetics.", "content": "Temperature-sensitive mutants of toxinogenic corynebacteriophage beta. I. Genetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200513"} {"pmid": "4200514", "title": "Properties of an oncornavirus glycoprotein: evidence for its presence on the surface of virions and infected cells.", "content": "Properties of an oncornavirus glycoprotein: evidence for its presence on the surface of virions and infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200514"} {"pmid": "4200516", "title": "In vitro action of bufexamac and selected hydroxamic acids on isolated rat liver lysosomes.", "content": "In vitro action of bufexamac and selected hydroxamic acids on isolated rat liver lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200516"} {"pmid": "4200517", "title": "Effect of glibenclamide upon 45 calcium efflux from perifused islets.", "content": "Effect of glibenclamide upon 45 calcium efflux from perifused islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200517"} {"pmid": "4200519", "title": "Application of the radial immunodiffusion method to the study of IgG and the free light chains of immunoglobulins in the tubular and glomerular proteinuria.", "content": "Application of the radial immunodiffusion method to the study of IgG and the free light chains of immunoglobulins in the tubular and glomerular proteinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200519"} {"pmid": "4200520", "title": "The synthesis of nucleic acids in Bacillus subtilis infected with phage PBS 1.", "content": "The synthesis of nucleic acids in Bacillus subtilis infected with phage PBS 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200520"} {"pmid": "4200521", "title": "Structural studies on antigen E of ragweed pollen.", "content": "Structural studies on antigen E of ragweed pollen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200521"} {"pmid": "4200522", "title": "Ocular abnormalities among congenitally deaf children.", "content": "Ocular abnormalities among congenitally deaf children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200522"} {"pmid": "4200523", "title": "Preventive treatment of tuberculin-negative contacts.", "content": "Preventive treatment of tuberculin-negative contacts. Five children who had been in close contact with highly infectious tuberculous individuals presented recently to the tuberculosis service of The Montreal Children's Hospital. Four had developed serious pulmonary tuberculosis and one tuberculous meningitis, all within the three months which followed a post-contact negative tuberculin test.The management of tuberculin-negative children recently exposed to active infectious tuberculosis by repeated skin tests and chest radiography alone is inadequate for their protection. These children are at high risk of developing disease by the time their tuberculin sensitivity has become evident. It is inadvisable to vaccinate them with BCG until three months after their last exposure to the disease. A plea is made for preventive chemotherapy in these cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200523"} {"pmid": "4200526", "title": "Diazepam and benzoctamlne: effects on certain objective parameters of muscular spasticity.", "content": "Diazepam and benzoctamlne: effects on certain objective parameters of muscular spasticity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200526"} {"pmid": "4200527", "title": "Flurazepam versus diazepam in an anaesthesia: a clinical study.", "content": "Flurazepam versus diazepam in an anaesthesia: a clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200527"} {"pmid": "4200528", "title": "Comprehensive clinical studies with trazodone.", "content": "Comprehensive clinical studies with trazodone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200528"} {"pmid": "4200518", "title": "Suppression of acute and chronic inflammation in adrenalectomized rats by pharmacologic amounts of prostaglandins.", "content": "Suppression of acute and chronic inflammation in adrenalectomized rats by pharmacologic amounts of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200518"} {"pmid": "4200529", "title": "A controlled study of the clinical effects of amantadine hydrochloride (Symmetrel).", "content": "A controlled study of the clinical effects of amantadine hydrochloride (Symmetrel).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200529"} {"pmid": "4200530", "title": "The comparative effects of SE1520, frusemide, and cyclopenthiazide in healthy subjects.", "content": "The comparative effects of SE1520, frusemide, and cyclopenthiazide in healthy subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200530"} {"pmid": "4200531", "title": "Treatment of chronic staphylococcal osteomyelitis with minocycline hydrochloride: a case report.", "content": "Treatment of chronic staphylococcal osteomyelitis with minocycline hydrochloride: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200531"} {"pmid": "4200532", "title": "Attempts at prophylaxis for murine Pneumocystis carinii pneumonitis.", "content": "Attempts at prophylaxis for murine Pneumocystis carinii pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200532"} {"pmid": "4200533", "title": "Immunological properties of a trypanosomal lipopolysaccharide and its effects on the infection with Trypanosoma (Schizotrypanum) cruzi.", "content": "Immunological properties of a trypanosomal lipopolysaccharide and its effects on the infection with Trypanosoma (Schizotrypanum) cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200533"} {"pmid": "4200534", "title": "Quantitative aspects of the migration inhibition reaction.", "content": "Quantitative aspects of the migration inhibition reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200534"} {"pmid": "4200535", "title": "Immunoadsorbent purification of antisera to impure abnormal serum antigens. Application to murine leukemia plasma virus.", "content": "Immunoadsorbent purification of antisera to impure abnormal serum antigens. Application to murine leukemia plasma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200535"} {"pmid": "4200536", "title": "A factor in respiratory tract secretions interfering with the ammonium sulfate test of Farr.", "content": "A factor in respiratory tract secretions interfering with the ammonium sulfate test of Farr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200536"} {"pmid": "4200538", "title": "Transformation of lymphocytes in gonorrhea before and after therapy.", "content": "Transformation of lymphocytes in gonorrhea before and after therapy. Patients were studied for lymphocyte transformation responses to a variety of Neisseria gonorrhoeae antigens and to a Neisseria catarrhalis sonicate. Cells from infected patients manifested significant uptake of tritiated thymidine in response to one or more gonococcal antigens. In some cases, deoxyribonucleic acid synthesis was so marked in lymphocytes not challenged by antigens in vitro that added blastogenesis was either obscured or inhibited. At five weeks posttherapy, lymphocytes were relatively nonreactive to gonococcal antigenic stimulation. Blastogenesis in response to N. catarrhalis was also seen for a few gonorrhea patients and normal controls. Cross-antigenicity of catarrhalis organisms and gonococci was indicated by the disappearance of reactivity to catarrhalis sonicate by the lymphocytes of almost all convalescent gonorrhea patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200538"} {"pmid": "4200537", "title": "Rubella immunization of volunteers via the respiratory tract.", "content": "Rubella immunization of volunteers via the respiratory tract. The efficacy of various routes of administration of the live attenuated rubella virus vaccine was evaluated by using 46 seronegative volunteers who were divided into 4 vaccine groups: subcutaneous, nosedrops, spray into posterior oropharynx and nose using large particle aerosol, and inhalation of small particle aerosol through the mouth. Seroconversion was observed in all of the vaccinees regardless of route of immunization. Nasal secretion antibody 6 weeks after immunization was highest in the volunteers who received the vaccine by nose drops (all members of this group had demonstrable nasal secretion antibody after immunization). Only half of the volunteers in the subcutaneous group developed demonstrable nasal secretion antibody. This suggests that nasal secretion antibody was best stimulated when vaccine was given directly into the nose. Volunteers were challenged with the vaccine intranasally at 6 to 8 weeks. None of the volunteers exhibited clinical symptoms or fourfold or greater serum antibody rises after challenge, but fourfold or greater nasal secretion antibody rises were observed in three volunteers in the subcutaneous vaccine group and two in the aerosol group, suggesting that those volunteers had not been protected against challenge. Rubella virus was isolated 8 to 12 days after challenge in two persons in the subcutaneous group and three in the aerosol vaccine group, but none in the nose drops or spray groups. Thus, protection after nasal challenge appeared to be best in those groups which also had the best nasal secretion antibody response after immunization. However, protection did not seem to be correlated with either nasal secretion or serum antibody levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200537"} {"pmid": "4200539", "title": "Mechanisms of immunity in typhus infections. I. Multiplication of typhus rickettsiae in human macrophage cell cultures in the nonimmune system: influence of virulence of rickettsial strains and of chloramphenicol.", "content": "Mechanisms of immunity in typhus infections. I. Multiplication of typhus rickettsiae in human macrophage cell cultures in the nonimmune system: influence of virulence of rickettsial strains and of chloramphenicol. Monocytes from the peripheral blood of nonimmune human subjects transformed in cell culture into macrophages with increased phagocytic capacity for killed typhus rickettsiae. When such cells were exposed to living virulent Rickettsia mooseri (Wilmington strain) or R. prowazeki (Breinl strain), or to the attenuated E strain of R. prowazeki, in the presence of medium containing normal human serum, all three strains readily entered the macrophage, but the subsequent fate varied according to strain and its virulence. Thus, R. mooseri grew readily to attain very high intracellular populations which eventually destroyed the macrophage in 3 to 5 days and escaped to infect other cells. Virulent R. prowazeki also grew at about the same rate for the first 2 to 3 days but then often abruptly ceased to multiply. Circumstantial evidence suggests a toxic effect on host cells by smaller numbers of R. prowazeki organisms than with R. mooseri. The attenuated E strain of R. prowazeki failed to grow in most cells and eventually disappeared, but did grow to substantial numbers in the very rare cell in some cultures, suggesting the presence of a few cells which may not be typical macrophages. The growth of R. mooseri in the macrophage cytoplasm was inhibited by chloramphenicol in the culture medium. When the drug was removed after 3 days, growth began after a lag period and assumed a normal rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200539"} {"pmid": "4200540", "title": "Immunological quantitation of hepatic tryptophan oxygenase in endotoxin-poisoned mice.", "content": "Immunological quantitation of hepatic tryptophan oxygenase in endotoxin-poisoned mice. An apparent inhibition of induction of mouse hepatic tryptophan oxygenase by endotoxin has been reported previously, as evidenced by low catalytic activity. This could be due either to decreased tryptophan oxygenase levels or to inactivation of existing enzyme molecules. To resolve this question, the enzyme was quantitated immunologically in control and endotoxin-poisoned mice. Tryptophan oxygenase was purified and used as an antigen to prepare antienzyme antibodies. The antiserum was shown to be monospecific by immuno-electrophoresis. Addition of the antiserum to high-speed supernatant fluids of liver homogenates of control or endotoxin-poisoned mice resulted in precipitation of the enzyme. Radial immunodiffusion assays revealed that there was less enzyme in livers of mice that received 1 mean lethal dose of endotoxin. It was concluded that endotoxin interfered with the synthetic process that results in enhanced levels of tryptophan oxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200540"} {"pmid": "4200541", "title": "Stimulation of anti-Brucella vaccination in mice by tetramisole, a phenyl-imidothiazole salt.", "content": "Stimulation of anti-Brucella vaccination in mice by tetramisole, a phenyl-imidothiazole salt. The effect of tetramisole (hydrochloride of racemic 2, 3, 5, 6,-tetrahydro-6-phenyl-imidazo [2, 1-b] thiazole) on immunization was investigated in mice vaccinated by killed Brucella melitensis cells suspended in incomplete adjuvant. Immunity to Brucella abortus challenge was estimated by the reduction in number of B. abortus colonies per gram of spleen in those mice which escaped full immunization and also by calculation of mean infective doses for each group of mice. All tetramisole treatments significantly reduced the number of B. abortus live cells in spleen from infected mice. Tetramisole, injected twice (at the time of vaccination and 48 h later), induced a significant 3.5-fold increase of the protection brought about by Brucella vaccine alone. A single injection of 1.25 mg/kg at the time of vaccination resulted also in a significant increase of the immunity given by vaccination. No modifications of the vaccine potency were observed if tetramisole administration preceded vaccination. In such a mouse assay, tetramisole-induced stimulation was not accompanied by specific antibody increases, although measured by three serological tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200541"} {"pmid": "4200542", "title": "Effect of heat-labile factors on the neutralization of vaccinia virus by human.", "content": "Effect of heat-labile factors on the neutralization of vaccinia virus by human. The effect of unheated guinea pig and human prevaccination serum on the neutralization of vaccinia virus was studied. Enhancement of neutralization was found in all sera containing antibody and was more marked (20- to 150-fold) in sera obtained in the first weeks after primary vaccination than in sera from immune adults or cord sera (4- to 25-fold). The enhancing factor was thought to be complement because it was destroyed by heating and ethylenediaminetetraacetic acid treatment. The fresh serum-enhanced neutralization test represents a highly sensitive and specific test which can be applied to measure low levels of vaccinia antibody not detectable by other means.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200542"} {"pmid": "4200543", "title": "Antibody responses to meningococcal polysaccharide vaccines.", "content": "Antibody responses to meningococcal polysaccharide vaccines. Over the past 4 years 19 lots of group C polysaccharide vaccine and five lots of group A polysaccharide vaccine have been tested for their immunogenicity in man. For each lot tested, groups of 18 to 50 men received 50 mug of vaccine subcutaneously. Sera were obtained prior to and 2 weeks after vaccination. The analytical and serological methods used in these studies were Sepharose 4B chromatography for the estimation of molecular size, the radioactive antigen binding assay, and the indirect hemagglutination (IHA) test for measuring the antibody response. Results have shown that the radioactive antigen binding assay is preferable to the IHA test as a measure of antibody response. Group C meningococcal vaccines have been highly stable when stored at 4 C in powdered form. All lots of group C vaccine tested to date have been of equal potency, with molecular weight varying from 520,000 to 2,000,000. Group A polysaccharides have been found to be unstable after 2 years of storage at 4 C. Optimal antibody response to the group A vaccines appears to be directly related to the molecular size of the preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200543"} {"pmid": "4200544", "title": "Resistance to Mycoplasma synoviae is bursal dependent.", "content": "Resistance to Mycoplasma synoviae is bursal dependent. Bursectomizing small bursa line birds produced susceptibility to Mycoplasma synoviae. This suggested that M. synoviae is B cell dependent, but does not rule out a T cell effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200544"} {"pmid": "4200545", "title": "A system of intravenous hyperalimentation.", "content": "A system of intravenous hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200545"} {"pmid": "4200547", "title": "A new approach to diverticula of the inner part of the second duodenum.", "content": "A new approach to diverticula of the inner part of the second duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200547"} {"pmid": "4200546", "title": "Predictive oncology. 1.", "content": "Predictive oncology. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200546"} {"pmid": "4200548", "title": "The fine structure of the retinal transient layer of Chievitz.", "content": "The fine structure of the retinal transient layer of Chievitz.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200548"} {"pmid": "4200549", "title": "Is there a potential defect in the blood-retinal barrier at the choroidal level of the optic nerve canal?", "content": "Is there a potential defect in the blood-retinal barrier at the choroidal level of the optic nerve canal?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200549"} {"pmid": "4200550", "title": "Spectrofluorometric determination of carbidopa (L-(-)-alpha-hydrazino-3, 4-dihydroxy-alpha-methylhydrocinnamic acid) in plasma.", "content": "Spectrofluorometric determination of carbidopa (L-(-)-alpha-hydrazino-3, 4-dihydroxy-alpha-methylhydrocinnamic acid) in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200550"} {"pmid": "4200552", "title": "Treatment of gonorrhea. Tetracyclines.", "content": "Treatment of gonorrhea. Tetracyclines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200552"} {"pmid": "4200553", "title": "II. Transportation systems in the diagnosis of gonorrhea.", "content": "II. Transportation systems in the diagnosis of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200553"} {"pmid": "4200555", "title": "Acute alterations in the bactericidal capacity of rabbit alveolar macrophages following stress.", "content": "Acute alterations in the bactericidal capacity of rabbit alveolar macrophages following stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200555"} {"pmid": "4200554", "title": "The role of diphosphonates in osteoporosis of disuse.", "content": "The role of diphosphonates in osteoporosis of disuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200554"} {"pmid": "4200559", "title": "Purification and some properties of isocitrate lyase from Pinus pinea.", "content": "Purification and some properties of isocitrate lyase from Pinus pinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200559"} {"pmid": "4200558", "title": "Biophysical characterization of a mitogenic erythro- and lympho-agglutinating phytohemagglutinin (PPHA) of Phaseolus vulgaris.", "content": "Biophysical characterization of a mitogenic erythro- and lympho-agglutinating phytohemagglutinin (PPHA) of Phaseolus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200558"} {"pmid": "4200560", "title": "Performance under temporal schedules by monkeys with partial ablations of prefontal cortex.", "content": "Performance under temporal schedules by monkeys with partial ablations of prefontal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200560"} {"pmid": "4200561", "title": "Comparison of behavioral effects of nicotine, d-amphetamine, caffeine and dimethylheptyl tetrahydrocannabinol in squirrel monkeys.", "content": "Comparison of behavioral effects of nicotine, d-amphetamine, caffeine and dimethylheptyl tetrahydrocannabinol in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200561"} {"pmid": "4200562", "title": "Macromolecular synthesis and cell division in x-irradiated Tetrahymena.", "content": "Macromolecular synthesis and cell division in x-irradiated Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200562"} {"pmid": "4200566", "title": "Antibody and antibiotic action on Rickettsia prowazeki in body lice across the host-vector interface, with observations on strain virulence and retrieval mechanisms.", "content": "Antibody and antibiotic action on Rickettsia prowazeki in body lice across the host-vector interface, with observations on strain virulence and retrieval mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200566"} {"pmid": "4200568", "title": "Amniotic fluid creatinine in the Rh-sensitized pregnancy.", "content": "Amniotic fluid creatinine in the Rh-sensitized pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200568"} {"pmid": "4200569", "title": "Umbilical blood flow, cardiac output, and organ blood flow in the immature baboon fetus.", "content": "Umbilical blood flow, cardiac output, and organ blood flow in the immature baboon fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200569"} {"pmid": "4200567", "title": "Epidemiology of hepatitis B antigen in Panama.", "content": "Epidemiology of hepatitis B antigen in Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200567"} {"pmid": "4200570", "title": "Effect of inotropic agents on canine trabecular muscle rendered highly permeable to calcium.", "content": "Effect of inotropic agents on canine trabecular muscle rendered highly permeable to calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200570"} {"pmid": "4200571", "title": "Glycogen of the brain and vital organs of monkeys recovering from systemic ischemia.", "content": "Glycogen of the brain and vital organs of monkeys recovering from systemic ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200571"} {"pmid": "4200565", "title": "Pseudomonas aeruginosa contamination of hydrophilic contact lenses and solutions.", "content": "Pseudomonas aeruginosa contamination of hydrophilic contact lenses and solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200565"} {"pmid": "4200572", "title": "Retinal laser damage thresholds as a function of image diameter.", "content": "Retinal laser damage thresholds as a function of image diameter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200572"} {"pmid": "4200573", "title": "The free flap: composite tissue transfer by vascular anastomosis.", "content": "The free flap: composite tissue transfer by vascular anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200573"} {"pmid": "4200574", "title": "The effects of protein deprivation on dominance measured by shock avoidance competition and food competition.", "content": "The effects of protein deprivation on dominance measured by shock avoidance competition and food competition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200574"} {"pmid": "4200576", "title": "Sialic acid deficiency of human red blood cells associated with persistent red cell, leucocyte, and platelet polyagglutinability.", "content": "Sialic acid deficiency of human red blood cells associated with persistent red cell, leucocyte, and platelet polyagglutinability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200576"} {"pmid": "4200575", "title": "Significance of large red blood cells.", "content": "Significance of large red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200575"} {"pmid": "4200577", "title": "Evaluation of spinal inhibitory activity in epilepsy by the H wave recovery curve.", "content": "Evaluation of spinal inhibitory activity in epilepsy by the H wave recovery curve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200577"} {"pmid": "4200564", "title": "Symposium: microsurgery of the outflow channels. Laboratory research.", "content": "Symposium: microsurgery of the outflow channels. Laboratory research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200564"} {"pmid": "4200579", "title": "Psychological studies of patients with epilepsy and popular prejudice.", "content": "Psychological studies of patients with epilepsy and popular prejudice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200579"} {"pmid": "4200578", "title": "Depamide in the treatment of epilepsy. A clinical trial.", "content": "Depamide in the treatment of epilepsy. A clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200578"} {"pmid": "4200580", "title": "Effect of head and body tilt on flicker-induced nystagmus in monkeys.", "content": "Effect of head and body tilt on flicker-induced nystagmus in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200580"} {"pmid": "4200581", "title": "Dietary management of diverticular disease.", "content": "Dietary management of diverticular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200581"} {"pmid": "4200583", "title": "Homogeneous glycogen synthetase b from rat liver.", "content": "Homogeneous glycogen synthetase b from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200583"} {"pmid": "4200582", "title": "Bovine pyruvate kinases. I. Purification and characterization of the skeletal muscle isozyme.", "content": "Bovine pyruvate kinases. I. Purification and characterization of the skeletal muscle isozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200582"} {"pmid": "4200584", "title": "Characterization of phycocyanin from Chromonas species.", "content": "Characterization of phycocyanin from Chromonas species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200584"} {"pmid": "4200587", "title": "Control of infectious hazards for the biophotographer.", "content": "Control of infectious hazards for the biophotographer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200587"} {"pmid": "4200585", "title": "Microsomal electron transport. The role of reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in liver microsomal lipid peroxidation.", "content": "Microsomal electron transport. The role of reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in liver microsomal lipid peroxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200585"} {"pmid": "4200586", "title": "A new alpha-D-mannosidase occurring in Golgi membranes.", "content": "A new alpha-D-mannosidase occurring in Golgi membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200586"} {"pmid": "4200589", "title": "An in-vivo stimulatory effect of 3,3',5-tri-iodo-L-thyronine on polyphenol oxidase activity in an ascidian.", "content": "An in-vivo stimulatory effect of 3,3',5-tri-iodo-L-thyronine on polyphenol oxidase activity in an ascidian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200589"} {"pmid": "4200588", "title": "Prolactin release induced by synthetic thyrotrophin releasing factor in female rats.", "content": "Prolactin release induced by synthetic thyrotrophin releasing factor in female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200588"} {"pmid": "4200590", "title": "Experimental infection of dogs and monkeys with two rabies serogroup viruses, Lagos bat and Mokola (IbAn 27377): clinical, serologic, virologic, and fluorescent-antibody studies.", "content": "Experimental infection of dogs and monkeys with two rabies serogroup viruses, Lagos bat and Mokola (IbAn 27377): clinical, serologic, virologic, and fluorescent-antibody studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200590"} {"pmid": "4200591", "title": "Exotoxins of Pseudomonas aeruginosa. I. Factors that influence the production of exotoxin A.", "content": "Exotoxins of Pseudomonas aeruginosa. I. Factors that influence the production of exotoxin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200591"} {"pmid": "4200592", "title": "Exotoxins of Pseudomonas aeruginosa. II. Concentration, purification, and characterization of exotoxin A.", "content": "Exotoxins of Pseudomonas aeruginosa. II. Concentration, purification, and characterization of exotoxin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200592"} {"pmid": "4200593", "title": "Exotoxins of Pseudomonas aeruginosa. 3. Characteristics of antitoxin A.", "content": "Exotoxins of Pseudomonas aeruginosa. 3. Characteristics of antitoxin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200593"} {"pmid": "4200594", "title": "Combinations of edetic acid and antibiotics in the treatment of rat burns infected with a resistant strain of Pseudomonas aeruginosa.", "content": "Combinations of edetic acid and antibiotics in the treatment of rat burns infected with a resistant strain of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200594"} {"pmid": "4200595", "title": "Brief communication: a continuous in vitro source of Herpesvirus saimiri.", "content": "Brief communication: a continuous in vitro source of Herpesvirus saimiri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200595"} {"pmid": "4200596", "title": "Transformation of cell cultures as an indication of the carcinogenic potential of chemicals.", "content": "Transformation of cell cultures as an indication of the carcinogenic potential of chemicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200596"} {"pmid": "4200598", "title": "Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine.", "content": "Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200598"} {"pmid": "4200597", "title": "Hormonal regulation of rapidly labeled RNA in normal preneoplastic and neoplastic tissues of mouse mammary gland.", "content": "Hormonal regulation of rapidly labeled RNA in normal preneoplastic and neoplastic tissues of mouse mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200597"} {"pmid": "4200599", "title": "A single method for measuring total thyroxine and free thyroxine index in serum.", "content": "A single method for measuring total thyroxine and free thyroxine index in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200599"} {"pmid": "4200600", "title": "Antibody production in protein calorie malnutrition.", "content": "Antibody production in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200600"} {"pmid": "4200601", "title": "Oxalosis caused by aspergilus infection.", "content": "Oxalosis caused by aspergilus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200601"} {"pmid": "4200602", "title": "Letter: Effects of vitamin E: good and bad.", "content": "Letter: Effects of vitamin E: good and bad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200602"} {"pmid": "4200603", "title": "Letter: Serology of toxoplasmosis, isosporosis and sarcosporidiosis.", "content": "Letter: Serology of toxoplasmosis, isosporosis and sarcosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200603"} {"pmid": "4200604", "title": "Prenatal hypothyroidism and brain composition in a primate.", "content": "Prenatal hypothyroidism and brain composition in a primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200604"} {"pmid": "4200605", "title": "pH-dependent changes in composition of carcinoembryonic antigen.", "content": "pH-dependent changes in composition of carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200605"} {"pmid": "4200606", "title": "Ventilation of toad lungs in the absence of the buccopharyngeal pump.", "content": "Ventilation of toad lungs in the absence of the buccopharyngeal pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200606"} {"pmid": "4200607", "title": "Letter: Infection and transformation of bovine lymphoid cells in vitro by infective particles of Theileria parva.", "content": "Letter: Infection and transformation of bovine lymphoid cells in vitro by infective particles of Theileria parva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200607"} {"pmid": "4200608", "title": "Fetal infection of the baboon (Papio cynocephalus) with vaccinia virus.", "content": "Fetal infection of the baboon (Papio cynocephalus) with vaccinia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200608"} {"pmid": "4200609", "title": "Comparison of temperature and pH effects on cells, walls, and autolysin of Listeria monocytogenes.", "content": "Comparison of temperature and pH effects on cells, walls, and autolysin of Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200609"} {"pmid": "4200610", "title": "Comparative effects of ovarian steroids on glycogen metabolism of rat, rabbit and guinea pig uterine tissue.", "content": "Comparative effects of ovarian steroids on glycogen metabolism of rat, rabbit and guinea pig uterine tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200610"} {"pmid": "4200611", "title": "Early life nutritional deprivation: persistent alteration of blood and urine amino acids in mice.", "content": "Early life nutritional deprivation: persistent alteration of blood and urine amino acids in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200611"} {"pmid": "4200612", "title": "Calcification and decalcification rates in vitro. A new technique.", "content": "Calcification and decalcification rates in vitro. A new technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200612"} {"pmid": "4200613", "title": "Responses of rat kidney and toad bladder to the pentapeptide ring structures of neurohypophysial hormones.", "content": "Responses of rat kidney and toad bladder to the pentapeptide ring structures of neurohypophysial hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200613"} {"pmid": "4200614", "title": "Diamide: a new radiosensitizer for anoxic cells.", "content": "Diamide: a new radiosensitizer for anoxic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200614"} {"pmid": "4200615", "title": "Diagnostic and prognostic value of some tests of autoimmune hemolytic anemia in diseases of the lymphoreticular system.", "content": "Diagnostic and prognostic value of some tests of autoimmune hemolytic anemia in diseases of the lymphoreticular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200615"} {"pmid": "4200616", "title": "Anthrax in Iran.", "content": "Anthrax in Iran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200616"} {"pmid": "4200617", "title": "Oxymetholone treatment in hypoproliferative anaemia. I. Frequency of response.", "content": "Oxymetholone treatment in hypoproliferative anaemia. I. Frequency of response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200617"} {"pmid": "4200618", "title": "Correlation between oestriol levels and serum iron-binding capacity in pregnancy.", "content": "Correlation between oestriol levels and serum iron-binding capacity in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200618"} {"pmid": "4200619", "title": "Quantitative studies of macrophages in blood cultures in chronic lymphocytic leukaemia.", "content": "Quantitative studies of macrophages in blood cultures in chronic lymphocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200619"} {"pmid": "4200620", "title": "A new anomaly of platelet aggregation. A report of two families.", "content": "A new anomaly of platelet aggregation. A report of two families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200620"} {"pmid": "4200621", "title": "Thrombocytopathia with abnormalities in platelet release reaction. Some evidence for platelet factor 4 deficiency.", "content": "Thrombocytopathia with abnormalities in platelet release reaction. Some evidence for platelet factor 4 deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200621"} {"pmid": "4200622", "title": "Screening of blood donors for hepatitis-associated antigen and antibody.", "content": "Screening of blood donors for hepatitis-associated antigen and antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200622"} {"pmid": "4200623", "title": "Automated seroagglutination test with Brucella and salmonella suspensions.", "content": "Automated seroagglutination test with Brucella and salmonella suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200623"} {"pmid": "4200624", "title": "Implant with postoperative drain after evisceration.", "content": "Implant with postoperative drain after evisceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200624"} {"pmid": "4200625", "title": "The effect of tobramycin on Pseudomonas keratitis.", "content": "The effect of tobramycin on Pseudomonas keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200625"} {"pmid": "4200626", "title": "Selection of treatment in squamous carcinoma of the floor of the mouth.", "content": "Selection of treatment in squamous carcinoma of the floor of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200626"} {"pmid": "4200627", "title": "Clinical evaluation of a 10 percent intravenous fat emulsion for parenteral nutrition in thermally injured patients.", "content": "Clinical evaluation of a 10 percent intravenous fat emulsion for parenteral nutrition in thermally injured patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200627"} {"pmid": "4200628", "title": "Effects of estrogen upon bile: implications with respect to gallstone formation.", "content": "Effects of estrogen upon bile: implications with respect to gallstone formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200628"} {"pmid": "4200629", "title": "Total body potassium measurements as a guide to intravenous alimentation.", "content": "Total body potassium measurements as a guide to intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200629"} {"pmid": "4200630", "title": "Effects of various gases on the survival of dried bacteria during storage.", "content": "Effects of various gases on the survival of dried bacteria during storage. Salmonella newport and Pseudomonas fluorescens were dried together in papain digest broth and sucrose-glutamate, and stored in several gases at various water activities (a(w)) between 0.00 and 0.40 at 25 C for various periods up to 81 weeks. Both S. newport and P. fluorescens, dried in papain digest broth and stored in air, died rapidly if the conditions were very dry (0.00 a(w)) or moist (0.40 a(w)). Storage in carbon dioxide and argon gave greater survival than storage in air but lower survival than did storage in nitrogen or in vacuo. When the organisms were dried in a sucrose-glutamate mixture the differences between the gases were very small, and variations in residual water were less important. Of the inert gases, argon gave the best survival when the organisms were dried in papain digest broth, especially at 0.00 a(w); the survival in neon and krypton was lower and in xenon and helium it was much lower.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200630"} {"pmid": "4200631", "title": "Rapid method for detection of Pseudomonas aeruginosa on MacConkey agar under ultraviolet light.", "content": "Rapid method for detection of Pseudomonas aeruginosa on MacConkey agar under ultraviolet light. A simple screening technique for the detection of Pseudomonas aeruginosa colonies by their fluorescence on MacConkey agar under ultraviolet light is proposed. From 306 nonlactose fermenting cultures screened under the ultraviolet light, 108 fluorescent isolates were obtained. These were screened biochemically, with 103 (94.8%) being verified as P. aeruginosa. From the 198 nonfluorescing cultures, only one suspected P. aeruginosa was isolated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200631"} {"pmid": "4200633", "title": "Continuous pressure monitoring in experimental obstructive hydrocephalus. I. The dynamics of acute ventricular obstruction.", "content": "Continuous pressure monitoring in experimental obstructive hydrocephalus. I. The dynamics of acute ventricular obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200633"} {"pmid": "4200632", "title": "The perforated diverticulum of the duodenum.", "content": "The perforated diverticulum of the duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200632"} {"pmid": "4200634", "title": "Continuous pressure monitoring in experimental obstructive hydrocephalus. II. The origin of undulating ventricular waves and periodic respirations.", "content": "Continuous pressure monitoring in experimental obstructive hydrocephalus. II. The origin of undulating ventricular waves and periodic respirations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200634"} {"pmid": "4200636", "title": "The identification of a unique p-nitrophenol conjugating enzyme in guinea pig liver microsomes.", "content": "The identification of a unique p-nitrophenol conjugating enzyme in guinea pig liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200636"} {"pmid": "4200635", "title": "On porcine enterokinase. Further purification and some molecular properties.", "content": "On porcine enterokinase. Further purification and some molecular properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200635"} {"pmid": "4200637", "title": "On the relation of heavy metals to the activity and heat stability of alkaline phosphatase from human placenta.", "content": "On the relation of heavy metals to the activity and heat stability of alkaline phosphatase from human placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200637"} {"pmid": "4200639", "title": "Altered response to scrapie tissues in neurological disease. Possible evidence for an antigen associated with reactive astrocytes.", "content": "Altered response to scrapie tissues in neurological disease. Possible evidence for an antigen associated with reactive astrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200639"} {"pmid": "4200638", "title": "Experimental kuru in the chimpanzee. A neuropathological study.", "content": "Experimental kuru in the chimpanzee. A neuropathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200638"} {"pmid": "4200640", "title": "Digitalis as an antianginal agent.", "content": "Digitalis as an antianginal agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200640"} {"pmid": "4200641", "title": "Interstitial pulmonary fibrosis and von Recklinghausen's disease. An ultrastructural and immunofluorescent study.", "content": "Interstitial pulmonary fibrosis and von Recklinghausen's disease. An ultrastructural and immunofluorescent study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200641"} {"pmid": "4200642", "title": "Endobronchial tuberculosis.", "content": "Endobronchial tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200642"} {"pmid": "4200643", "title": "Incontinentia pigmenti: a systemic genodermatosis with striking cutaneous findings.", "content": "Incontinentia pigmenti: a systemic genodermatosis with striking cutaneous findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200643"} {"pmid": "4200644", "title": "Gonococcal infections in infants and children. Lessons from fifteen cases.", "content": "Gonococcal infections in infants and children. Lessons from fifteen cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200644"} {"pmid": "4200645", "title": "Surgical aspects of nontuberculous bacterial meningitis in infancy and childhood. The successful use of conservative surgery in management of some of its complications.", "content": "Surgical aspects of nontuberculous bacterial meningitis in infancy and childhood. The successful use of conservative surgery in management of some of its complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200645"} {"pmid": "4200646", "title": "Some recent concepts on anterior pituitary control.", "content": "Some recent concepts on anterior pituitary control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200646"} {"pmid": "4200647", "title": "Suppression of chicken immunoglobulin ontogeny by F(ab')2 fragments of anti-mu chain and by anti-L chain.", "content": "Suppression of chicken immunoglobulin ontogeny by F(ab')2 fragments of anti-mu chain and by anti-L chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200647"} {"pmid": "4200648", "title": "Synthesis, intracellular distribution, and secretion of immunoglobulin and H-2 antigen in muring splenocytes.", "content": "Synthesis, intracellular distribution, and secretion of immunoglobulin and H-2 antigen in muring splenocytes. A/J spleen cells were labeled with [(3)H]leucine and at intervals thereafter were homogenized and separated into microsomes and cell sap. Ig and H-2 antigens were assayed in the cell fractions and cell supernatants using immunoprecipitation. In addition, cells labeled by enzymatic radioiodination were incubated to determine the rates of release of Ig and H-2 antigens from the surface. The results indicate that the majority of Ig and H-2 antigens remain membrane bound throughout their intracellular life. In contrast to Ig, H-2 antigens are neither secreted nor shed from the cell surface. It is suggested that Ig is a peripheral protein of the cell membrane, whereas H-2 antigens are integral ones. The release of Ig on a fragment of plasma membrane could occur at fixed cell surface areas that contain no H-2 antigens or from which they have migrated before release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200648"} {"pmid": "4200649", "title": "The enhancement of macrophage bacteriostasis by products of activated lymphocytes.", "content": "The enhancement of macrophage bacteriostasis by products of activated lymphocytes. It was reported previously that the incubation of normal guinea pig macrophages with partially purified products of activated lymphocytes resulted in altered macrophage function including increased cell adherence to culture vessels, spreading, phagocytosis, and glucose carbon-1 oxidation. Studies reported here demonstrate that such macrophages also exhibit enhanced bacteriostasis. Lymphocytes were stimulated with concanavalin A, the culture supernatant was chromatographed over Sephadex G-100 and the fraction of mol wt 25,000-55,000, rich in lymphocyte mediators, was cultured with normal guinea pig macrophages for 1-3 days. Macrophages incubated with fractions from unstimulated lymphocyte cultures served as controls. The resulting macrophage monolayers were infected with Listeria monocytogenes. Macrophages incubated with mediator-rich fractions exhibited 2- to 10-fold enhanced bacteriostasis compared to controls. Further studies indicate that this enhancement was attributable to intrinsic changes in the macrophages and not simply a consequence of the number of macrophages on the monolayers. The studies support the concept that macrophage bacteriostasis can be enhanced by lymphocyte mediators. However, macrophages, which have been preincubated directly with sensitive lymphocytes and antigen exhibit even greater bacteriostasis and sometimes bactericidal capacity, suggesting that either a labile lymphocyte factor or direct lymphocyte macrophage interaction may also be involved in bactericidal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200649"} {"pmid": "4200652", "title": "Comparative activity of bacterial beta-lactamases on penicillins and cephalosporins.", "content": "Comparative activity of bacterial beta-lactamases on penicillins and cephalosporins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200652"} {"pmid": "4200650", "title": "Monoclonal macroglobulinemia in NZB-NZW F1 mice.", "content": "Monoclonal macroglobulinemia in NZB-NZW F1 mice. Serum monoclonal macroglobulins were detected in over 30% of NZB/NZW F(1) mice greater than 11 mo of age. The monoclonal nature of the IgM was shown by restricted electrophoretic mobility, characteristic appearance on immunoelectrophoresis, restriction to a single light chain type, and ability to induce anti-idiotypic antisera. The monoclonal macroglobulins were separated from antibodies to DNA and RNA that migrated in the 7S region of sucrose gradients. Enlarged lymph nodes were often present in mice with monoclonal IgM, and a transplantable IgM-producing lymphoid tumor was established from the spleen of one animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200650"} {"pmid": "4200651", "title": "In vitro activity of cefazolin against recent clinical bacterial isolates.", "content": "In vitro activity of cefazolin against recent clinical bacterial isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200651"} {"pmid": "4200653", "title": "Studies on therapy of staphylococcal infections in monkeys. 8. Comparison of cephalothin, cephaloridine, cefazolin, cephacetrile, and cephanone.", "content": "Studies on therapy of staphylococcal infections in monkeys. 8. Comparison of cephalothin, cephaloridine, cefazolin, cephacetrile, and cephanone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200653"} {"pmid": "4200654", "title": "Cefazolin in the treatment of gonorrhea.", "content": "Cefazolin in the treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200654"} {"pmid": "4200656", "title": "Tularaemic pneumonia: pathogenesis of the aerosol-induced disease in monkeys.", "content": "Tularaemic pneumonia: pathogenesis of the aerosol-induced disease in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200656"} {"pmid": "4200655", "title": "Cefazolin in the treatment of uncomplicated gonorrhea in men.", "content": "Cefazolin in the treatment of uncomplicated gonorrhea in men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200655"} {"pmid": "4200657", "title": "The natural history of platelet-rich mural thrombi in systemic arteries of hypercholesterolaemic monkeys: light- and electron-microscope observations.", "content": "The natural history of platelet-rich mural thrombi in systemic arteries of hypercholesterolaemic monkeys: light- and electron-microscope observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200657"} {"pmid": "4200658", "title": "A clinical and histologic assessment of subperiosteal implants.", "content": "A clinical and histologic assessment of subperiosteal implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200658"} {"pmid": "4200660", "title": "Short small-bowel syndrome.", "content": "Short small-bowel syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200660"} {"pmid": "4200659", "title": "The effect of human granulocyte elastase on bacterial suspensions.", "content": "The effect of human granulocyte elastase on bacterial suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200659"} {"pmid": "4200662", "title": "Microbiological studies on non-gonococcal urethritis in Brisbane.", "content": "Microbiological studies on non-gonococcal urethritis in Brisbane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200662"} {"pmid": "4200661", "title": "Prophylaxis against septicaemia in acute leukaemia: the use of oral framycetin.", "content": "Prophylaxis against septicaemia in acute leukaemia: the use of oral framycetin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200661"} {"pmid": "4200663", "title": "Cromolyn sodium.", "content": "Cromolyn sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200663"} {"pmid": "4200665", "title": "Intramembranous particle aggregation in lymphoid cells.", "content": "Intramembranous particle aggregation in lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200665"} {"pmid": "4200664", "title": "Prostaglandin production and bone resorption by dental cysts.", "content": "Prostaglandin production and bone resorption by dental cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200664"} {"pmid": "4200666", "title": "Gammopathy in hamsters with xenogeneic tumours.", "content": "Gammopathy in hamsters with xenogeneic tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200666"} {"pmid": "4200670", "title": "The transmission of Sarcocystis tenella in sheep.", "content": "The transmission of Sarcocystis tenella in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200670"} {"pmid": "4200671", "title": "The effect of heterologous anti-thymocyte serum upon the course of infection with Trypanosoma cruzi in Mice.", "content": "The effect of heterologous anti-thymocyte serum upon the course of infection with Trypanosoma cruzi in Mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200671"} {"pmid": "4200669", "title": "The intranuclear development of Toxoplasma.", "content": "The intranuclear development of Toxoplasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200669"} {"pmid": "4200673", "title": "Studies on colostral antibodies to Theileria parva using the indirect fluorescent antibody test.", "content": "Studies on colostral antibodies to Theileria parva using the indirect fluorescent antibody test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200673"} {"pmid": "4200674", "title": "Chagas' heart disease. First demonstrable correlation between neuronal degeneration and autonomic impairment.", "content": "Chagas' heart disease. First demonstrable correlation between neuronal degeneration and autonomic impairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200674"} {"pmid": "4200676", "title": "Left ventricular function in patients with coronary artery disease.", "content": "Left ventricular function in patients with coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200676"} {"pmid": "4200677", "title": "Myocardial transit times from intracoronary dye-dilution curves in normal subjects and patients with coronary artery disease.", "content": "Myocardial transit times from intracoronary dye-dilution curves in normal subjects and patients with coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200677"} {"pmid": "4200678", "title": "Renovascular hypertension in the pediatric patient.", "content": "Renovascular hypertension in the pediatric patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200678"} {"pmid": "4200679", "title": "Development of large-scale fractionation methods. IV. A simple method for the large-scale preparation of alpha1-acid glycoprotein.", "content": "Development of large-scale fractionation methods. IV. A simple method for the large-scale preparation of alpha1-acid glycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200679"} {"pmid": "4200680", "title": "Tactile discrimination performance in the monkey: the effect of commissure section on transfer of training between the hands.", "content": "Tactile discrimination performance in the monkey: the effect of commissure section on transfer of training between the hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200680"} {"pmid": "4200667", "title": "Effect of neuroleptics on aggressive behavior.", "content": "Effect of neuroleptics on aggressive behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200667"} {"pmid": "4200684", "title": "Studies on the biosynthesis of malate dehydrogenase isozymes in rabbit liver. Isolation of the in vivo labelled isozymes by specific antibodies.", "content": "Studies on the biosynthesis of malate dehydrogenase isozymes in rabbit liver. Isolation of the in vivo labelled isozymes by specific antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200684"} {"pmid": "4200685", "title": "Hydrosoluble adjuvant-active mycobacterial fractions of low molecular weight.", "content": "Hydrosoluble adjuvant-active mycobacterial fractions of low molecular weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200685"} {"pmid": "4200686", "title": "Genetic control of insect population. I. Cage studies of chromosome replacement by compound autosomes in Drosophila melanogaster.", "content": "Genetic control of insect population. I. Cage studies of chromosome replacement by compound autosomes in Drosophila melanogaster. A genetic method for insect control was evaluated using the test organism, Drosophila melanogaster. The technique involved the displacement under a system of continuous reproduction, of standard strains by those carrying compound autosomes. The eradication of the replacements could subsequently be achieved through the use of temperature-sensitive lethal mutations.-While certain compound autosome strains failed to displace standards in population cages, even at the initial release ratio of 25:1, others were highly successful. Indeed, for some strains when the ratio of compounds to standards was as low as 9:1, the population rapidly went to fixation in favor of the compound line.-Hatchability was found to be an insufficient index of fitness to estimate the initial ratios of compounds to standards that would guarantee fixation of the former. Differences in other fitness components, such as development time, were detected that could seriously modify displacement, especially with continuous overlapping generations. The importance of examining the fitness of various compound lines and selecting the most competitive in cages, prior to field tests, cannot be overemphasized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200686"} {"pmid": "4200687", "title": "Differential response to selection on the two sexes in Drosophila melanogaster.", "content": "Differential response to selection on the two sexes in Drosophila melanogaster. Artificial selection for short wing was performed in two Drosophila melanogaster populations with partially different gene pools: the C populations were derived from a Canton stock while the H lines were derived from a cross between Canton and a b, cn, vg strain. It is shown that in both populations selection on females (CF, HF) was more effective than selection on males (CM, HM). This difference cannot be explained in terms of differences in additive genetic variability between the two sexes because: (1) both sexes contribute to the genetic variability utilized by selection applied to one sex only, and (2) switching selection pressure on females in the M lines does not result in a response comparable to that obtained in the F populations; this rules out almost completely recombination as the responsible agent for the differences between the selection limits reached by M and F selections.-These results, together with several additional observations concerning sexual dimorphism, fitness and the effect of natural selection, suggest that a complex interaction should be involved in the differential response of M and F lines, controlling the wing length phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200687"} {"pmid": "4200689", "title": "A convenient method for liquid scintillation counting of barium carbonate-14C.", "content": "A convenient method for liquid scintillation counting of barium carbonate-14C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200689"} {"pmid": "4200690", "title": "Anthrax in Louisiana, 1971: an evaluation of the Sterne strain anthrax vaccine.", "content": "Anthrax in Louisiana, 1971: an evaluation of the Sterne strain anthrax vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200690"} {"pmid": "4200675", "title": "Pharmacological comparison between tolbutamide and two second generation hypoglycemic sulfonylureas (glibenclamide and glisoxepide).", "content": "Pharmacological comparison between tolbutamide and two second generation hypoglycemic sulfonylureas (glibenclamide and glisoxepide).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200675"} {"pmid": "4200688", "title": "On the genetics of the primary generalized epilepsy with sporadic myoclonias of impulsive petit mal type. A clinical and electroencephalographic study of 399 probands.", "content": "On the genetics of the primary generalized epilepsy with sporadic myoclonias of impulsive petit mal type. A clinical and electroencephalographic study of 399 probands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200688"} {"pmid": "4200691", "title": "Anthrax in Louisiana, 1971: epizootiologic study.", "content": "Anthrax in Louisiana, 1971: epizootiologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200691"} {"pmid": "4200693", "title": "Electroencephalographic correlates of delayed-alternation and visual discrimination learning in rhesus monkeys.", "content": "Electroencephalographic correlates of delayed-alternation and visual discrimination learning in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200693"} {"pmid": "4200692", "title": "A gas chromatographic method of quantitating DDT in the presence of interfering polychlorinated biphenyl.", "content": "A gas chromatographic method of quantitating DDT in the presence of interfering polychlorinated biphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200692"} {"pmid": "4200694", "title": "Isolation of glucosamine from the capsids of a picornavirus.", "content": "Isolation of glucosamine from the capsids of a picornavirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200694"} {"pmid": "4200695", "title": "Long term infection of diploid African green monkey brain cells by Schwarz measles vaccine virus.", "content": "Long term infection of diploid African green monkey brain cells by Schwarz measles vaccine virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200695"} {"pmid": "4200696", "title": "Anthrax. Biological and immunological principles of diagnosis and prevention. Communication 7. Diagnosis of anthrax by means of anthraxin.", "content": "Anthrax. Biological and immunological principles of diagnosis and prevention. Communication 7. Diagnosis of anthrax by means of anthraxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200696"} {"pmid": "4200697", "title": "Effect of glucose or glycerin in cultivation media on the fatty acid composition of Listeria monocytogenes.", "content": "Effect of glucose or glycerin in cultivation media on the fatty acid composition of Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200697"} {"pmid": "4200699", "title": "Localization of calcium antimonate in the atrial and ventricular muscle fibers of the cat heart.", "content": "Localization of calcium antimonate in the atrial and ventricular muscle fibers of the cat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200699"} {"pmid": "4200698", "title": "Serum immuno-globulins in children with bilharzial infection.", "content": "Serum immuno-globulins in children with bilharzial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200698"} {"pmid": "4200700", "title": "Transmission of three strains of Plasmodium falciparum from monkey to man.", "content": "Transmission of three strains of Plasmodium falciparum from monkey to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200700"} {"pmid": "4200701", "title": "Studies on human malaria in aotus monkeys. 3. Exoerythrocytic stages of the Salvador II strain of Plasmodium vivax.", "content": "Studies on human malaria in aotus monkeys. 3. Exoerythrocytic stages of the Salvador II strain of Plasmodium vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200701"} {"pmid": "4200702", "title": "Difference in surface charge between host cells and malarial parasites.", "content": "Difference in surface charge between host cells and malarial parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200702"} {"pmid": "4200703", "title": "Failure of holothurin to significantly affect Chagas' disease in mice.", "content": "Failure of holothurin to significantly affect Chagas' disease in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200703"} {"pmid": "4200704", "title": "Effect of progesteroids on the cellular response to inflammation in the monkey.", "content": "Effect of progesteroids on the cellular response to inflammation in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200704"} {"pmid": "4200705", "title": "Virulence of rifampicin-resistant mutants of Shigella and enteropathogenic Escherichia coli with special reference to their cell invasiveness.", "content": "Virulence of rifampicin-resistant mutants of Shigella and enteropathogenic Escherichia coli with special reference to their cell invasiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200705"} {"pmid": "4200706", "title": "Slime production by Pseudomonas aeruginosa. 3. Purification of slime and its physicochemical properties.", "content": "Slime production by Pseudomonas aeruginosa. 3. Purification of slime and its physicochemical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200706"} {"pmid": "4200709", "title": "Triazenes, a new group of indirect mutagens. Comparative investigations of the genetic effects of different Aryldialkyltriazenes using Saccharomyces cerevisiae, the host-mediated assay, Drosophila melanogaster, and human chromosomes in vitro.", "content": "Triazenes, a new group of indirect mutagens. Comparative investigations of the genetic effects of different Aryldialkyltriazenes using Saccharomyces cerevisiae, the host-mediated assay, Drosophila melanogaster, and human chromosomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200709"} {"pmid": "4200711", "title": "Comparative mutagenic activity and toxicity of triethylphosphate and dichlorvos in bacteria and Drosophila.", "content": "Comparative mutagenic activity and toxicity of triethylphosphate and dichlorvos in bacteria and Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200711"} {"pmid": "4200712", "title": "Invited discussion: Approaches to the serologic characterization of Hodgkin's disease.", "content": "Invited discussion: Approaches to the serologic characterization of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200712"} {"pmid": "4200713", "title": "Invited discussion: Tumor-associated antigen in Hodgkin's disease.", "content": "Invited discussion: Tumor-associated antigen in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200713"} {"pmid": "4200714", "title": "Complications of intensive megavoltage radiotherapy for Hodgkin's disease.", "content": "Complications of intensive megavoltage radiotherapy for Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200714"} {"pmid": "4200715", "title": "Modern radiotherapy in carcinoma of the larynx.", "content": "Modern radiotherapy in carcinoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200715"} {"pmid": "4200716", "title": "Endoscopic treatment of esophageal diverticula.", "content": "Endoscopic treatment of esophageal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200716"} {"pmid": "4200708", "title": "Physicochemical investigation of DNP preparations obtained at low ionic strength.", "content": "Physicochemical investigation of DNP preparations obtained at low ionic strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200708"} {"pmid": "4200717", "title": "Glycogen metabolism of human diploid fibroblast cells in culture. I. Studies of cells from patients with glycogenosis types II, 3, and V.", "content": "Glycogen metabolism of human diploid fibroblast cells in culture. I. Studies of cells from patients with glycogenosis types II, 3, and V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200717"} {"pmid": "4200719", "title": "Meningococcal meningitis presenting as acute cerebellar ataxia.", "content": "Meningococcal meningitis presenting as acute cerebellar ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200719"} {"pmid": "4200718", "title": "Mucolipidosis 3 (Pseudo-Hurler polydystrophy): multiple lysosomal enzyme abnormalities in serum and cultured fibroblast cells.", "content": "Mucolipidosis 3 (Pseudo-Hurler polydystrophy): multiple lysosomal enzyme abnormalities in serum and cultured fibroblast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200718"} {"pmid": "4200720", "title": "Inactivation of enzymes induced by substrate: a model and some considerations.", "content": "Inactivation of enzymes induced by substrate: a model and some considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200720"} {"pmid": "4200721", "title": "Primer activity of a low molecular weight glycogen from a patient with an unusual glycogen storage disease.", "content": "Primer activity of a low molecular weight glycogen from a patient with an unusual glycogen storage disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200721"} {"pmid": "4200722", "title": "Differentiation in Nostoc muscorum: nitrogenase is synthesized in heterocysts.", "content": "Differentiation in Nostoc muscorum: nitrogenase is synthesized in heterocysts. Cellular differentiation can be observed in certain filamentous blue-green algae after transfer of the cells from medium containing NH(4) (+) or NO(3) (-) to nitrogen-free medium. The appearance of differentiated cells (heterocysts) is accompanied by an increase in the activity of nitrogenase, an enzyme complex that reduces N(2) to NH(3). We have separated vegetative cells from heterocysts in differentiated filaments of Nostoc muscorum, and analyzed their proteins by polyacrylamide-gel electrophoresis. The pattern of incorporation of (35)SO(4) (-) into proteins of the two cell types during differentiation indicates that the increase in nitrogenase activity is due to the de novo synthesis of nitrogenase proteins predominantly, if not exclusively, in heterocysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200722"} {"pmid": "4200723", "title": "Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis.", "content": "Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis. Among affected members of a family (B. family) with excessive purine production and gout, activity of phosphoribosylpyrophosphate synthetase (EC 2.7.6.1) is 2.5- to 3.0-fold higher than among normal people. The molecular basis for this increased enzyme activity was studied. Antibody to purified human phosphoribosylpyrophosphate synthetase of erythrocytes was obtained from immunized rabbits. Studies with the IgG fraction of this antiserum show the presence of normal quantities of immunoreactive enzyme, but 2.5- to 3.0-fold higher activity per molecule in affected members of the B. family. In addition, by use of a stain for phosphoribosylpyrophosphate synthetase activity, a difference in electrophoretic mobility was demonstrated on cellulose acetate gel between the partially purified enzyme from normal people and an affected member of the B. family. These studies suggest that the enzyme aberration responsible for purine overproduction and gout in the B. family results from a structurally altered enzyme with increased activity per molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200723"} {"pmid": "4200724", "title": "Strychnine binding associated with glycine receptors of the central nervous system.", "content": "Strychnine binding associated with glycine receptors of the central nervous system. [(3)H]Strychnine binds to synaptic-membrane fractions of the spinal cord in a selective fashion, indicating an interaction with postsynaptic glycine receptors. Displacement of strychnine by glycine and other amino acids parallels their glycine-like neurophysiologic activity. The regional localization of strychnine binding in the central nervous system correlates closely with endogenous glycine concentrations. In subcellular fractionation experiments, strychnine binding is most enhanced in synaptic-membrane fractions. Strychnine binding is saturable, with affinity constants for glycine and strychnine of 10 and 0.03 muM, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200724"} {"pmid": "4200725", "title": "Proton-coupled accumulation of galactoside in Streptococcus lactis 7962.", "content": "Proton-coupled accumulation of galactoside in Streptococcus lactis 7962. When cells of the anaerobe Streptococcus lactis 7962 are deprived of their normal fermentable energy source, active transport of galactosides is completely abolished although the membrane carriers are still capable of facilitating the equilibration of sugars across the cell membrane. In these nonmetabolizing cells it was possible to test the Mitchell hypothesis of obligatory coupling of proton movement with sugar transport. This hypothesis was supported by alkalinization of the medium observed when thiomethylgalactoside was added to a lightly buffered suspension of S. lactis cells. Conversely, addition of protons resulted in active transport of thiomethylgalactoside. Accumulation of thiomethylgalactoside to a concentration more than 20-times that in the external medium was induced by suddenly exposing cells to a medium at pH 6; no accumulation of thiomethylgalactoside was observed with cells exposed to pH 8.Active transport of thiomethylgalactoside occurred in the absence of energy metabolism when S. lactis cells were treated with valinomycin. This ionophore allowed intracellular K(+) to flow out, thus imposing a membrane potential (inside negative). This potential resulted in a proton uptake and an associated active transport of galactoside. The membrane potential was measured from the distribution ratio (inside/outside) of K(+) in the presence of valinomycin. The pH gradient was measured from the distribution ratio of [(14)C]methylamine. The protonmotive force, calculated from the membrane potential and the pH gradient, was found to be directly related to the accumulation of galactoside, in accordance with the chemiosmotic hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200725"} {"pmid": "4200726", "title": "Survey of DNA polymerase activity during the early development of Drosophila melanogaster.", "content": "Survey of DNA polymerase activity during the early development of Drosophila melanogaster. The pattern of DNA polymerase activity in developing Drosophila melanogaster has been studied in seven stages of embryonic development as well as in unfertilized eggs. The crude polymerase-containing extracts, most likely of cytoplasmic origin, utilize, in the following order of decreasing template efficiency, \"activated\" calfthymus DNA, poly(A).oligo(dT), and poly(A).oligo(U). The highest enzymes levels occur in unfertilized eggs; the activity remains high during the first 9 hr of embryogenesis, but shows a progressive decline in the later stages. Deoxyribonuclease exhibits a similar trend. The unfertilized eggs of two genotypically different females had nearly identical levels of DNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200726"} {"pmid": "4200727", "title": "Relation of detergent HLB number to solubilization and stabilization of D-alanine carboxypeptidase from Bacillus subtilis membranes.", "content": "Relation of detergent HLB number to solubilization and stabilization of D-alanine carboxypeptidase from Bacillus subtilis membranes. The ability of various nonionic detergents to solubilize D-alanine carboxypeptidase and other membrane-bound enzymes was correlated to a physical property of the detergent, the HLB number. Only a fairly narrow range of detergents were effective solubilizing agents. Purified carboxypeptidase required either a detergent or detergent plus a lipid fraction for stability. Only those detergents effective in solubilizing the enzyme were effective in stabilizing it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200727"} {"pmid": "4200728", "title": "Australia antibody production elicited by heat-treated human plasma protein solution.", "content": "Australia antibody production elicited by heat-treated human plasma protein solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200728"} {"pmid": "4200729", "title": "The production in the pregnant cow of anti-human immunoglobulin to be used for the antiglobulin test.", "content": "The production in the pregnant cow of anti-human immunoglobulin to be used for the antiglobulin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200729"} {"pmid": "4200730", "title": "Evidence of the existence of the rhesus complex Cde (r') in a Chinese.", "content": "Evidence of the existence of the rhesus complex Cde (r') in a Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200730"} {"pmid": "4200731", "title": "The treatment of angina pectoris.", "content": "The treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200731"} {"pmid": "4200733", "title": "Sequenced external counterpulsation and intraaortic balloon pumping in cardiogenic shock.", "content": "Sequenced external counterpulsation and intraaortic balloon pumping in cardiogenic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200733"} {"pmid": "4200735", "title": "Central effects of 6-hydroxydopamine.", "content": "Central effects of 6-hydroxydopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200735"} {"pmid": "4200734", "title": "Visual defect does not produce stereotyped movements.", "content": "Visual defect does not produce stereotyped movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200734"} {"pmid": "4200736", "title": "A statistical method for the classification of behavior untis occurring in primate communication.", "content": "A statistical method for the classification of behavior untis occurring in primate communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200736"} {"pmid": "4200738", "title": "Comparative methods for isolation of polysomes from the oviduct of laying hen.", "content": "Comparative methods for isolation of polysomes from the oviduct of laying hen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200738"} {"pmid": "4200740", "title": "Studies on the bacteriophage MS2. XXII. Conformation of MS2 RNA in acid medium.", "content": "Studies on the bacteriophage MS2. XXII. Conformation of MS2 RNA in acid medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200740"} {"pmid": "4200739", "title": "The ribosomal cycle in bacteria treated with an inhibitor of protein synthesis.", "content": "The ribosomal cycle in bacteria treated with an inhibitor of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200739"} {"pmid": "4200741", "title": "Antigenic variation in current human type A influenza viruses: antigenic characteristics of the variants and their geographic distribution.", "content": "Antigenic variation in current human type A influenza viruses: antigenic characteristics of the variants and their geographic distribution. Outbreaks of influenza due to the virus A/Hong Kong/1/68 (H3N2) began in 1968 and are still occurring. The haemagglutinin of this virus is different from that of the A/Singapore/1/57 virus (the \"Asian\" strain) but the neuraminidase antigens are the same. Between 1968 and 1971 only minor antigenic \"drift\" in the haemagglutinin was noted, but in recent months 2 isolates have been identified in which considerable \"drift\" has occurred in the haemagglutinin and in the neuraminidase antigens. One, A/Hong Kong/5/72 (H3N2), was first detected in outbreaks in Hong Kong between November 1971 and January 1972 and was predominant there and in Korea but did not become widely disseminated. The second strain, A/England/42/72 (H3N2), has been isolated in winter outbreaks in the southern hemisphere and now appears to be the predominant strain in the northern hemisphere. The characteristics of the strains are described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200741"} {"pmid": "4200742", "title": "Quantitative differentiation of Yersinia pestis strains by their murine toxin and fraction I contents.", "content": "Quantitative differentiation of Yersinia pestis strains by their murine toxin and fraction I contents. Until now the serological typing of Yersinia pestis into subgroups has not proved possible because all the antigenic components are present in each isolate. Using acrylamide disk electrophoresis it was observed that differences exist in the protein distribution patterns of aqueous extracts from various Y. pestis isolates. One component that was especially plentiful in some Javanese and South American isolates was identified as the murine toxin. The amount of murine toxin varies significantly from isolate to isolate, and so permits them to be roughly grouped. In 28 degrees C cultures the variation in the murine toxin content is independent of the variation in the F-I content. A new method of typing based on this 2-trait variation in quantities, in contrast to classical typing based on qualitative differences, might prove to be a means of differentiating Y. pestis isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200742"} {"pmid": "4200744", "title": "[Pathological basis for radiodiagnosis of ulcerative carcinoma and benign stomach ulcer].", "content": "[Pathological basis for radiodiagnosis of ulcerative carcinoma and benign stomach ulcer].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200744"} {"pmid": "4200766", "title": "Determination of gold in drugs and serum by use of anodic stripping voltammetry.", "content": "Determination of gold in drugs and serum by use of anodic stripping voltammetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200766"} {"pmid": "4200767", "title": "Relationships among urinary aminoimidazolecarboxamide in urine and folate, and vitamin B12 concentrations in serum.", "content": "Relationships among urinary aminoimidazolecarboxamide in urine and folate, and vitamin B12 concentrations in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200767"} {"pmid": "4200768", "title": "A simplified determination of urinary cadmium, lead, and thallium, with use of carbon rod atomization and atomic absorption spectrophotometry.", "content": "A simplified determination of urinary cadmium, lead, and thallium, with use of carbon rod atomization and atomic absorption spectrophotometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200768"} {"pmid": "4200769", "title": "Gametocytocidal and sporontocidal effects of antimalarial drugs on malaria parasites. I. Effect of single and multiple doses of primaquine on Plasmodium cynomolgi.", "content": "Gametocytocidal and sporontocidal effects of antimalarial drugs on malaria parasites. I. Effect of single and multiple doses of primaquine on Plasmodium cynomolgi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200769"} {"pmid": "4200770", "title": "Theileria lawrencei: infection in the Indian water buffalo, Bubalus bubalis.", "content": "Theileria lawrencei: infection in the Indian water buffalo, Bubalus bubalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200770"} {"pmid": "4200771", "title": "Ileal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethylene diphosphonate(C12 MDP) in the chick.", "content": "Ileal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethylene diphosphonate(C12 MDP) in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200771"} {"pmid": "4200772", "title": "N-Carbobenzoxy-L-pyroglutamyl-L-hitidyl peptides.", "content": "N-Carbobenzoxy-L-pyroglutamyl-L-hitidyl peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200772"} {"pmid": "4200773", "title": "Carbonic anhydrase activity in Rana pipiens skin: biochemical and histochemical analysis.", "content": "Carbonic anhydrase activity in Rana pipiens skin: biochemical and histochemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200773"} {"pmid": "4200774", "title": "Ultracentrifugal and immunological comparisons of succinylated human thyroglobulin and 27 S iodoprotein.", "content": "Ultracentrifugal and immunological comparisons of succinylated human thyroglobulin and 27 S iodoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200774"} {"pmid": "4200775", "title": "Release of endotoxin in the form of cell wall blebs during in vitro growth of Neisseria meningitidis.", "content": "Release of endotoxin in the form of cell wall blebs during in vitro growth of Neisseria meningitidis. Multiple cell wall blebs were observed on the surface of three strains of N. meningitidis taken from log phase cultures. The blebs originated as evaginations of the outer layer of the cell wall. Bleb production was noted on both defined or complex media either as broth or a solid medium. The addition of 10% normal bovine serum to the various media did not affect the production and release of these surface blebs. However, as broth cultures progressed into the stationary phase of growth, the blebs disappeared from the surface of the cells. Blebs were present in substantial quantities in culture supernatant fluids and on cell surfaces and were readily isolated by ultracentrifugation. Analysis for 2-keto-3-deoxyoctonate in cultures revealed that 18% of the total endotoxin of log phase cultures was present in blebs from the cell wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200775"} {"pmid": "4200777", "title": "Idiotypic specificity of rabbit antibodies to streptococcal group polysaccharides.", "content": "Idiotypic specificity of rabbit antibodies to streptococcal group polysaccharides. Anti-idiotypic antisera against six restricted rabbit streptococcal group specific antibodies have been raised in rabbits matched for allotypes. All these antisera reacted specifically with their homologous idiotypes on double-diffusion tests in agarose gel. In addition, they showed a high incidence of cross-specificities with group-specific hyperimmune sera induced in both closely related and unrelated individuals. These precipitating cross-specificities could be explained for two systems by the interference of rheumatoid factor. Two idiotypic antibody systems have been analyzed in detail; these were restricted antibodies produced in a father and in one of his offspring. The methods employed included binding inhibition of radio-labeled homologous Fab fragments and hemagglutination inhibition with homologous idiotypic coat. The data demonstrated that only related rabbits produced, besides non-cross-reacting antibodies, idiotypically similar antibodies raised to the same antigen. About one-third of the cross-reactive idiotypes showed binding inhibition between 31 and 92%. Inhibition of binding above 50% in the paternal idiotypic system was only achieved by one offspring antibody whereas the F(1) progeny idiotypic system was inhibited to this extent by seven antibodies of related rabbits. In contrast, 87.5% and 91.7% of antibodies of unrelated rabbits were less than 20% inhibitory. Within this study two idiotypically identical antibodies have not been found. This implies that A-variant-specific antibodies of related rabbits which produced antipolysaccharide antibodies were structurally different. Cross-reaction, even if greater than 90% by binding inhibition, appears to involve only part and not all of the variable regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200777"} {"pmid": "4200776", "title": "Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes.", "content": "Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes. Relatively pure populations of human T and B lymphocytes were obtained from blood and tonsils using density gradient centrifugation in bovine serum albumin. Antigen alone was incapable of triggering the B lymphocyte into blast transformation or to secrete antibody. However, supernatants from tetanus toxoid-stimulated T cells obtained from immune donors contained a factor mitogenic for B lymphocytes. 50-60% of B cells responded to this lymphocyte mitogenic factor (LMF) by proliferation, loss of C3 reactivity, and change to a secretory state. LMF-stimulated B cells exhibited a three- to fivefold increase in protein secretion and a six- to eightfold increase in gamma G globulin secretion. De novo secreted IgG had specificity directed to the tetanus toxoid present in the LMF containing T-cell supernatants. This was confirmed by an increase in the number of indirect plaque-forming cells to tetanus toxoid-coated sheep red blood cells after stimulation of B cells with LMF. It is proposed that in the course of the response to a previously encountered protein antigen, sensitized human T cells emit a signal in the form of a soluble product that, together with antigen, triggers B cells into division and antibody secretion. The experimental model utilized can be adapted to study human T-B cell cooperation under various conditions in normal individuals and in individuals with immunodeficiency diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200776"} {"pmid": "4200778", "title": "An electrophoretic difference between surface and secreted IgM of murine splenocytes.", "content": "An electrophoretic difference between surface and secreted IgM of murine splenocytes. micro-chains on the surface of murine splenocytes are more heterogeneous on SDS-polyacrylamide gel electrophoresis than both secreted and intracellular micro-chains labeled with [(3)H]tyrosine. No difference in heterogeneity among cell surface, secreted, or intracellular L chains was detected. The possible role of carbohydrate in micro-chain heterogeneity is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200778"} {"pmid": "4200779", "title": "Failure to demonstrate a humoral immune response to scrapie infection in mice.", "content": "Failure to demonstrate a humoral immune response to scrapie infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200779"} {"pmid": "4200780", "title": "An effector-cell independent step in target cell lysis by sensitized mouse lymphocytes.", "content": "An effector-cell independent step in target cell lysis by sensitized mouse lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200780"} {"pmid": "4200781", "title": "An agglutination-flocculation test for rapid detection of hepatitis B antigen.", "content": "An agglutination-flocculation test for rapid detection of hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200781"} {"pmid": "4200782", "title": "Identification of J-chain in polymeric immunoglobulins from a variety of species by cross-reaction with rabbit antisera to human J-chain.", "content": "Identification of J-chain in polymeric immunoglobulins from a variety of species by cross-reaction with rabbit antisera to human J-chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200782"} {"pmid": "4200783", "title": "Communication skills in five-year-old children with high-risk neonatal histories.", "content": "Communication skills in five-year-old children with high-risk neonatal histories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200783"} {"pmid": "4200784", "title": "The health and nutritional status of children in Tabora region, Tanzania.", "content": "The health and nutritional status of children in Tabora region, Tanzania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200784"} {"pmid": "4200785", "title": "The fate of the hospitalized malnourished child in Iran.", "content": "The fate of the hospitalized malnourished child in Iran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200785"} {"pmid": "4200787", "title": "A rural nutrition rehabilitation project at Kasangati health centre.", "content": "A rural nutrition rehabilitation project at Kasangati health centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200787"} {"pmid": "4200786", "title": "The operation and function of malwards in the Philippines.", "content": "The operation and function of malwards in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200786"} {"pmid": "4200792", "title": "Ancient linkage groups and frozen accidents.", "content": "Ancient linkage groups and frozen accidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200792"} {"pmid": "4200794", "title": "Mitosis in the Crypyophyvrsr.", "content": "Mitosis in the Crypyophyvrsr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200794"} {"pmid": "4200796", "title": "An automatic film densitometer and some applications in the field of radiotherapy.", "content": "An automatic film densitometer and some applications in the field of radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200796"} {"pmid": "4200795", "title": "The psychiatric nurse as therapist. 3. Operant treatment of the long-term patient.", "content": "The psychiatric nurse as therapist. 3. Operant treatment of the long-term patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200795"} {"pmid": "4200798", "title": "HL-A reagents from primates. I. Antigen preparation, immunization, and preliminary analysis of sera.", "content": "HL-A reagents from primates. I. Antigen preparation, immunization, and preliminary analysis of sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200798"} {"pmid": "4200799", "title": "Granulocyte alkaline phosphatase activity: a measure of the emergence time of mature marrow neutrophils?", "content": "Granulocyte alkaline phosphatase activity: a measure of the emergence time of mature marrow neutrophils?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200799"} {"pmid": "4200800", "title": "The treatment of terminal metamorphosis of chronic granulocytic leukaemia with corticosteroids and vincristine.", "content": "The treatment of terminal metamorphosis of chronic granulocytic leukaemia with corticosteroids and vincristine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200800"} {"pmid": "4200801", "title": "Spontaneous platelet aggregation in myeloproliferative disorders. A preliminary study.", "content": "Spontaneous platelet aggregation in myeloproliferative disorders. A preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200801"} {"pmid": "4200802", "title": "A comparison of the three in vivo assays for haemopoietic stem cells.", "content": "A comparison of the three in vivo assays for haemopoietic stem cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200802"} {"pmid": "4200804", "title": "Haemoglobin c in arabs in kuwait.", "content": "Haemoglobin c in arabs in kuwait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200804"} {"pmid": "4200803", "title": "Glucose-6-phosphate dehydrogenase electrophoresis in Ghanaians with AA and SS haemoglobin.", "content": "Glucose-6-phosphate dehydrogenase electrophoresis in Ghanaians with AA and SS haemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200803"} {"pmid": "4200805", "title": "Congenital thrombocytopathy (platelet factor 3 defect) with prolonged bleeding time but normal platelet adhesiveness and aggregation.", "content": "Congenital thrombocytopathy (platelet factor 3 defect) with prolonged bleeding time but normal platelet adhesiveness and aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200805"} {"pmid": "4200806", "title": "Hereditary persistence of fetal hemoglobin and beta-thalassemia in a Turkish child.", "content": "Hereditary persistence of fetal hemoglobin and beta-thalassemia in a Turkish child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200806"} {"pmid": "4200807", "title": "The levodopa test of growth hormone reserve in children.", "content": "The levodopa test of growth hormone reserve in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200807"} {"pmid": "4200808", "title": "Meningococcal meningitis following rifampin prophylaxis.", "content": "Meningococcal meningitis following rifampin prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200808"} {"pmid": "4200809", "title": "Congenital diverticulum of the left ventricle.", "content": "Congenital diverticulum of the left ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200809"} {"pmid": "4200810", "title": "Physiologic and pathologic profiles of circulating human prolactin.", "content": "Physiologic and pathologic profiles of circulating human prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200810"} {"pmid": "4200811", "title": "Onset of espundia after many years of occult infection with Leishmania braziliensis.", "content": "Onset of espundia after many years of occult infection with Leishmania braziliensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200811"} {"pmid": "4200812", "title": "Pathology of the testis and epididymis in the late phase of experimental Chagas's disease.", "content": "Pathology of the testis and epididymis in the late phase of experimental Chagas's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200812"} {"pmid": "4200813", "title": "Immunization with a zoophilic strain of Schistosoma japonicum: a re-evaluation of the Formosan strain of S. japonicum in rhesus monkeys.", "content": "Immunization with a zoophilic strain of Schistosoma japonicum: a re-evaluation of the Formosan strain of S. japonicum in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200813"} {"pmid": "4200814", "title": "Further observations on the primary paranasal aspergillus granuloma in the Sudan: a morphological study of 46 cases.", "content": "Further observations on the primary paranasal aspergillus granuloma in the Sudan: a morphological study of 46 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200814"} {"pmid": "4200816", "title": "Experimental pulmonary edema following re-expansion of pneumothorax.", "content": "Experimental pulmonary edema following re-expansion of pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200816"} {"pmid": "4200817", "title": "Miliary tuberculosis in a renal transplant recipient.", "content": "Miliary tuberculosis in a renal transplant recipient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200817"} {"pmid": "4200815", "title": "Exogenous reinfection with Mycobacterium tuberculosis confirmed by phage typing.", "content": "Exogenous reinfection with Mycobacterium tuberculosis confirmed by phage typing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200815"} {"pmid": "4200819", "title": "L-asparaginase activity in mycobacteria.", "content": "L-asparaginase activity in mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200819"} {"pmid": "4200818", "title": "Background factors for casual isolation of Mycobacterium intracellulare from sputum of patients with tuberculosis.", "content": "Background factors for casual isolation of Mycobacterium intracellulare from sputum of patients with tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200818"} {"pmid": "4200820", "title": "Effect of age on the enzymes of tricarboxylic acid and related cycles in Mycobacterium tuberculosis H37Rv.", "content": "Effect of age on the enzymes of tricarboxylic acid and related cycles in Mycobacterium tuberculosis H37Rv.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200820"} {"pmid": "4200821", "title": "Effects of cord factor on pyrazinamide deamidase.", "content": "Effects of cord factor on pyrazinamide deamidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200821"} {"pmid": "4200822", "title": "Fractionation of antigenic components of histoplasmin by disc electrophoresis.", "content": "Fractionation of antigenic components of histoplasmin by disc electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200822"} {"pmid": "4200823", "title": "Letter: Susceptibility tests and initial and primary drug resistance in tuberculosis.", "content": "Letter: Susceptibility tests and initial and primary drug resistance in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200823"} {"pmid": "4200824", "title": "Letter: Infection with Mycobacterium avium in monkeys.", "content": "Letter: Infection with Mycobacterium avium in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200824"} {"pmid": "4200826", "title": "Letter: Neurofibroma and nevoid basal cell carcinoma.", "content": "Letter: Neurofibroma and nevoid basal cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200826"} {"pmid": "4200825", "title": "Endemic superficial pyoderma in children.", "content": "Endemic superficial pyoderma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200825"} {"pmid": "4200827", "title": "Jugular vein compression and elevation of perilymphatic fluid pressure.", "content": "Jugular vein compression and elevation of perilymphatic fluid pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200827"} {"pmid": "4200828", "title": "Biochemical studies of the chromaffin granule. 3. Redistribution of lipid phosphate, dopamine-beta-hydroxylase and chromogranin A after freezing and thawing of the isolated granule membranes.", "content": "Biochemical studies of the chromaffin granule. 3. Redistribution of lipid phosphate, dopamine-beta-hydroxylase and chromogranin A after freezing and thawing of the isolated granule membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200828"} {"pmid": "4200829", "title": "Relevance of antigenicity of Candida albicans growth phases to diagnosis of systemic candidiasis.", "content": "Relevance of antigenicity of Candida albicans growth phases to diagnosis of systemic candidiasis. The antigenicity of the two growth phases of Candida albicans has been compared by using crossed immunoelectrophoresis and double-diffusion techniques. Qualitative and quantitative differences in antigenic composition between the phases have been revealed and moreover a specific mycelial antigenic component demonstrated.It is postulated that the use of specific mycelial antigens for routine diagnostic precipitin testing in patients with suspected systemic candidiasis would give more reliable results than at present obtained with yeast cell antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200829"} {"pmid": "4200830", "title": "The levels of superoxide dismutase and catalase in human tissues as determined immunochemically.", "content": "The levels of superoxide dismutase and catalase in human tissues as determined immunochemically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200830"} {"pmid": "4200831", "title": "Freeze-injury in bacteria.", "content": "Freeze-injury in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200831"} {"pmid": "4200833", "title": "Gliding motility of algae in unaffected by cytochalasin B.", "content": "Gliding motility of algae in unaffected by cytochalasin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200833"} {"pmid": "4200832", "title": "Properties of two growth-stimulating proteins isolated from fetal calf serum.", "content": "Properties of two growth-stimulating proteins isolated from fetal calf serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200832"} {"pmid": "4200835", "title": "Letter: Further evidence for a role of H202 in radiation sensitization of bacterial spores.", "content": "Letter: Further evidence for a role of H202 in radiation sensitization of bacterial spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200835"} {"pmid": "4200836", "title": "Influence of high-protein diets on renal function.", "content": "Influence of high-protein diets on renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200836"} {"pmid": "4200837", "title": "Resistance of Escherichia coli to penicillins: identification of the structural gene for the chromosomal penicillinase.", "content": "Resistance of Escherichia coli to penicillins: identification of the structural gene for the chromosomal penicillinase. A screening procedure was used to isolate a number of mutants of Escherichia coli K-12 with low penicillinase activity. By co-transduction with purA, three of the mutants were found to map near 82 min. Penicillinase was purified from one mutant and from a transductant with a temperature-sensitive enzyme. Comparison with wild-type penicillinase revealed similarities in the Ouchterlony immunodiffusion test but differences in the catalytic properties. It is concluded that the mutations have occurred in the structural gene of the chromosomal penicillinase (designated ampC). Purified enzyme and a temperature-sensitive mutant were used to investigate whether the penicillinase has a physiological function related to biosynthesis or breakdown of murein. No positive evidence for any such function was obtained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200837"} {"pmid": "4200839", "title": "Conditions affecting the isolation from transformed cells of Bacillus subtilis of high-molecular-weight single-stranded deoxyribonucleic acid of donor origin.", "content": "Conditions affecting the isolation from transformed cells of Bacillus subtilis of high-molecular-weight single-stranded deoxyribonucleic acid of donor origin. The deoxyribonucleic acid (DNA) extraction procedure of Piechowska and Fox was evaluated to determine which steps are required for the isolation of high-molecular-weight single-stranded material from transformed cultures of Bacillus subtilis. The results indicate that high-molecular-weight single-stranded DNA can be isolated when certain basic proteins are present at the time of lysis. In the absence of such protective agents as lysozyme or cytC the single-stranded DNA is degraded. The single-stranded DNA can also be protected by being treated with lysozyme at low temperature. The high molecular weight of this single-stranded material and its kinetics of appearance are consistent with its being an intermediate in the transformation process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200839"} {"pmid": "4200838", "title": "Initiation of deoxyribonucleic acid replication in a temperature-sensitive mutant of B. subtilis: evidence for a transcriptional step.", "content": "Initiation of deoxyribonucleic acid replication in a temperature-sensitive mutant of B. subtilis: evidence for a transcriptional step. A mutant of Bacillus subtilis unable to initiate a new round of replication at 45 C has been described. Here we show that inhibition of DNA synthesis in this mutant is reversible and that DNA synthesis is resumed at low temperature, even in the presence of chloramphenicol. Initiation of a new replication cycle thus can occur in the absence of protein synthesis. A thermolabile component required for initiation therefore appears to be synthesized at 45 C in an inactive form and can be activated at 30 C in the presence of an inhibitor of protein synthesis. Although resistant to chloramphenicol, the reinitiation of replication occurring after lowering the temperature is sensitive to rifampin and streptolydigin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200838"} {"pmid": "4200841", "title": "Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis.", "content": "Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis. A 70,000-dalton protein that is found in sporulating Bacillus subtilis and that binds to ribonucleic acid polymerase is present in asporogenous mutants that proceed to or beyond stage II of sporulation, but is absent from mutants blocked at stage zero.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200841"} {"pmid": "4200840", "title": "Kinetic analysis of the products of donor deoxyribonucleate in transformed cells of Bacillus subtilis.", "content": "Kinetic analysis of the products of donor deoxyribonucleate in transformed cells of Bacillus subtilis. This paper describes the major transmutations of donor deoxyribonucleic acid (DNA) after uptake by competent Bacillus subtilis cells. Kinetic experiments confirm that after exposure to competent cells, donor DNA is converted to double-stranded fragments (DSF) which can be isolated as early as 30 s from the beginning of the reaction. At this time, DSF represent the only identifiable product of donor origin. After 1 to 2 min, DSF are converted to deoxyribonuclease-resistant forms, identified as single-stranded DNA fragments (SSF). SSF are intermediates in the transformation process leading to the formation of donor-recipient complex. This component makes its appearance between 2 to 4 min from the beginning of the transformation process. All the donor-recipient complexes found at the end of the reaction can be accounted for quantitatively by the DSF and the SSF found in the initial stages of transformation. A quantitative discussion of the transformation process is included.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200840"} {"pmid": "4200843", "title": "Phycobilisomes from a blue-green alga Nostoc species.", "content": "Phycobilisomes from a blue-green alga Nostoc species. Phycobilisomes were isolated from a Nostoc sp. strain Mac in phosphate buffer (pH 7.0) by treatment with 1% Brij 56 and centrifugation on discontinuous sucrose gradients (2.0, 1.0, 0.5, and 0.25 M in the proportions 6:4:4:10 ml, respectively). Absorption spectra of isolated phycobilisomes showed the presence of phycoerythrin, phycocyanin, and allophycocyanin. The phycobilisome pigments were partially resolved by electrophoresis on acrylamide gels. Stained gels demonstrated that each main protein band corresponded to a pigmented region. The phycobilisomes appeared compact with a rounded surface and flattened base (about 40-nm diameter) at the attachment site to the photosynthetic lamellae. Fixation in glutaraldehyde caused a significant reduction in total pigment absorption, as well as shifts in the absorption maxima, particularly that of phycoerythrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200843"} {"pmid": "4200842", "title": "NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.", "content": "NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins. The NH(2)-terminal amino acid distribution of Streptococcus faecalis R soluble and ribosomal proteins isolated from cells at different stages of growth on either folate-sufficient or folate-deficient medium was determined by the dinitrophenyl method. The NH(2)-terminal residues do not follow the random distribution observed for the total amino acid composition of S. faecalis soluble and ribosomal proteins. Methionine and alanine occur most frequently; serine, threonine, aspartic and glutamic acids, and glycine are also present at the NH(2)-terminal position of S. faecalis R proteins. The absence of folic acid yields cells that are incapable of formylating methionyl-transfer ribonucelic acid tRNA(f) (Met), but does not affect either the qualitative or quantitative NH(2)-terminal distribution of total soluble or total ribosomal proteins compared to cells grown with folate. A small quantitative difference was observed in the frequency of distribution of certain amino acids at the NH(2)-termini between log and stationary phase soluble proteins. The amino acid residues found at the NH(2)-terminal position of S. faecalis proteins are qualitatively similar to those reported for several other organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200842"} {"pmid": "4200844", "title": "Gene-enzyme relationships of aromatic acid biosynthesis in Bacillus subtilis.", "content": "Gene-enzyme relationships of aromatic acid biosynthesis in Bacillus subtilis. Mutants have been isolated which correspond to every step concerned with the biosynthesis of the aromatic amino acids in Bacillus subtilis. Each mutant has been characterized, and the lesion it bore was analyzed by deoxyribonucleic acid transformation and PBS-1 mediated transduction. The biochemical analysis revealed that each of the mutations appears to have affected a single enzyme, except for two groups of pleiotropic mutations. All aroF mutants (chorismic acid synthetase) lack dehydroquinic acid synthetase (aroB) activity. The gene that specifies aroB is closely linked to the gene coding for the aroF enzyme. Both genes are a part of the aro cluster. Mutants lacking chorismate mutase activity also lack d-arabino-heptulosonic acid-7-phosphate synthetase and shikimate kinase activity, presumably as a result of these three activities forming a multi-enzyme complex. Another mutant, previously undescribed, had been isolated. The affected gene codes for the tyrosine and phenylalanine aminotransferase activity. All of the mutations have been located on the B. subtilis genome except those in the genes specifying shikimate kinase activity and tyrosine-phenylalanine aminotransferase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200844"} {"pmid": "4200846", "title": "Relationship between transformation in Bacillus subtilis and infection by bacteriophage SP02.", "content": "Relationship between transformation in Bacillus subtilis and infection by bacteriophage SP02. When bacteriophage SP02 infects a Bacillus subtilis culture during or shortly after transformation, the frequency of transformants among the resulting lysogens is greatly reduced relative to that in the uninfected culture. The effect can occur after the deoxyribonucleic acid has been taken up and covalently attached to recipient deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200846"} {"pmid": "4200847", "title": "Effect of low-intensity light on growth response and bacteriochlorophyll concentration in Rhodospirillum rubrum mutant C.", "content": "Effect of low-intensity light on growth response and bacteriochlorophyll concentration in Rhodospirillum rubrum mutant C. Photosynthesizing cells of Rhodospirillum rubrum mutant C underwent adaptation for growth in low-light conditions. During adaptation there was a transitory increase in the generation time and the bacteriochlorophyll a content of the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200847"} {"pmid": "4200845", "title": "Mode of action of glycine on the biosynthesis of peptidoglycan.", "content": "Mode of action of glycine on the biosynthesis of peptidoglycan. The mechanism of glycine action in growth inhibition was studied on eight different species of bacteria of various genera representing the four most common peptidoglycan types. To inhibit the growth of the different organisms to 80%, glycine concentrations from 0.05 to 1.33 M had to be applied. The inhibited cells showed morphological aberrations. It has been demonstrated that glycine is incorporated into the nucleotide-activated peptidoglycan precursors. The amount of incorporated glycine was equivalent to the decrease in the amount of alanine. With one exception glycine is also incorporated into the peptidoglycan. Studies on the primary structure of both the peptidoglycan precursors and the corresponding peptidoglycan have revealed that glycine can replace l-alanine in position 1 and d-alanine residues in positions 4 and 5 of the peptide subunit. Replacement of l-alanine in position 1 of the peptide subunit together with an accumulation of uridine diphosphate-muramic acid (UDP-MurNAc), indicating an inhibition of the UDP-MurNAc:l-Ala ligase, has been found in three bacteria (Staphylococcus aureus, Lactobacillus cellobiosus and L. plantarum). However, discrimination against precursors with glycine in position 1 in peptidoglycan synthesis has been observed only in S. aureus. Replacement of d-alanine residues was most common. It occurred in the peptidoglycan with one exception in all strains studied. In Corynebacterium sp., C. callunae, L. plantarum, and L. cellobiosus most of the d-alanine replacing glycine occurs C-terminal in position 4, and in C. insidiosum and S. aureus glycine is found C-terminal in position 5. It is suggested that the modified peptidoglycan precursors are accumulated by being poor substrates for some of the enzymes involved in peptidoglycan synthesis. Two mechanisms leading to a more loosely cross-linked peptidoglycan and to morphological changes of the cells are considered. First, the accumulation of glycine-containing precursors may lead to a disrupture of the normal balance between peptidoglycan synthesis and controlled enzymatic hydrolysis during growth. Second, the modified glycine-containing precursors may be incorporated. Since these are poor substrates in the transpeptidation reaction, a high percentage of muropeptides remains uncross-linked. The second mechanism may be the more significant in most cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200845"} {"pmid": "4200848", "title": "Accumulation of messenger ribonucleic acid specific for extracellular protease in Bacillus subtilis 168.", "content": "Accumulation of messenger ribonucleic acid specific for extracellular protease in Bacillus subtilis 168. Production of extracellular protease by Bacillus subtilis 168 in a medium containing low concentrations of amino acids is essentially linear, whereas in a medium containing high levels of amino acids the time course of production is biphasic. Cells harvested from the growth medium are capable of secreting enzyme for 30 min in the presence of rifampin, but the appearance of the enzyme is sensitive to chloramphenicol and pactamycin. The protease messenger ribonucleic acid (mRNA), nevertheless, appears to have a short half-life typical of bacterial messengers, and this indicates that these cells contain a relatively large pool of protease-specific mRNA. This pattern of results is identical to that observed previously with B. amyloliquefaciens. Because it has now been found in two distinct organisms, it is concluded that the accumulation of mRNA for extracellular protease, supported by rapid transcription, is a biologically meaningful phenomenon related to extracellular enzyme synthesis rather than aberrant behavior due to a transcriptional control mutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200848"} {"pmid": "4200849", "title": "Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes.", "content": "Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes. The derepression of the isoleucine and valine biosynthetic enzymes in Escherichia coli and Salmonella typhimurium was examined under conditions of restriction of isoleucine, valine, or leucine (the three amino acids needed for multivalent repression of these enzymes). A procedure was used that allowed the measurement of enzyme-forming potential that accumulated during the starvation period, but could not be expressed unless the missing amino acid was supplied. The threonine deaminase (the product of the ilvA gene)-forming potential that accumulated under such conditions was found to be unstable and decayed with a half-life of about 2.5 min (at 37 C). Evidence was obtained that indicates the threonine deaminase-forming potential that accumulates under conditions of isoleucine starvation is in the form of initiated (rifampin-resistant), but uncompleted (actinomycin D-sensitive), messenger ribonucleic acid chains. Furthermore, it appears that a large portion of the threonine deaminase- and dehydrase (the product of the ilvD gene)-forming potential, under such conditions, is in the form of initiated polypeptide chains. Based on these results and results obtained with SuA(-) strains, a model is presented that explains how the second gene (D) in the ilvADE operon can be partially transcribed and translated under conditions in which there are no completed messenger ribonucleic acids for the gene (A) transcribed before it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200849"} {"pmid": "4200850", "title": "Genetics and biochemistry of pyrimidine biosynthesis in Bacillus subtilis: linkage between mutations resulting in a requirement for uracil.", "content": "Genetics and biochemistry of pyrimidine biosynthesis in Bacillus subtilis: linkage between mutations resulting in a requirement for uracil. A number of independently derived uracil-requiring mutant strains of the parent strain 168 were mapped by inter-mutant transformation crosses. Only a few of these mutant strains were found to be transformable. Studies were performed in which these transformable uracil-requiring mutant strains were used as the recipient of deoxyribonucleic acid extracted from phenotypically similar mutant strains. The results yielded data resulting in a fine-structure map in which all mutations were found to be linked in a small region corresponding to that previously published as the uracil region of the Bacillus subtilis genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200850"} {"pmid": "4200851", "title": "Ribonucleic acid polymerase in a thermosensitive sporulation mutant (ts-4) of Bacillus subtilis.", "content": "Ribonucleic acid polymerase in a thermosensitive sporulation mutant (ts-4) of Bacillus subtilis. Partially synchronized cultures of a Bacillus subtilis thermosensitive sporulation mutant (ts-4) and the 168 try(-)try(-) (168tt) parental strain were infected with the virulent phage phie at various times during their growth cycle at 30 and 42 C (permissive and restrictive temperatures, respectively). It was shown that at the restrictive temperature the burst size in the parental strain was two- to threefold lower than in the ts-4 mutant. No such difference was observed at the permissive temperature. However, the time at which this difference was observed excludes a correlation between the burst size and initiation of the sporulation process. It was further found that the capacity to transcribe in vitro phage phie deoxyribonucleic acid by partially purified ribonucleic acid (RNA) polymerase from both strains decreased sharply if the source of enzyme was sporulating cells instead of vegetative ones. However, a similar decrease, although to a lesser extent, was observed with the RNA polymerase isolated from stationary-phase cells of the ts-4 mutant grown at the nonpermissive temperature, or with the enzyme derived from several other zero-stage sporulation mutants. At no time was a structural modification in the beta subunits of the RNA polymerase observed during growth of the sporulating bacteria. We have also shown that, in addition to the relatively low specific activity of the RNA polymerase, the level of the intracellular protease activity is about 15-fold lower in the ts-4 mutant grown at the restrictive temperature than that of the parental strain grown at the same temperature. At the permissive temperature no such difference was observed between these two strains. However, the present data do not allow us to establish a correlation among the low content of intracellular protease, the weak specific activity of the RNA polymerase, and the loss of the sporulation capacity in the ts-4 mutant grown at the restrictive temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200851"} {"pmid": "4200853", "title": "Genetic studies of leucine biosynthesis in Bacillus subtilis.", "content": "Genetic studies of leucine biosynthesis in Bacillus subtilis. The mutations in a series of leucine auxotrophs isolated after treatment with nitrosoguanidine, ultraviolet light, and ICR-191 have been mapped between ilvC and pheA on the Bacillus subtilis chromosome. A fine structure map of the region was constructed by transformation. Analysis of several strains by assaying levels of their leucine bioysnthetic enzymes has shown that the region encodes three enzymes. The order of the genes with respect to the biosynthetic steps catalyzed by the gene products is 1-3-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200853"} {"pmid": "4200852", "title": "Enzymes of the tryptophan pathway in three Bacillus species.", "content": "Enzymes of the tryptophan pathway in three Bacillus species. The tryptophan synthetic pathway was characterized in three species of Bacillus, B. subtilis, B. pumilus, and B. alvei. They share the common features of a pathway which is subject to tryptophan repression, contains no unexpected complexes among the five enzymes, exhibits dissociable anthranilate synthase enzymes which do not require phosphoribosyl transferase for amidetransfer activity, contains separate indoleglycerol phosphate synthase and phosphoribosylanthranilate isomerase enzymes, and contains similar tryptophan synthetase multimers. In looking at these characteristics in detail however, differences among the three species became apparent, as, for example, in the complementation observed between the alpha and beta(2) components of tryptophan synthetase, and the dissociation patterns of the large and small components of anthranilate synthase. The results demonstrate some pitfalls in attempting to compare multimeric enzymes in crude extracts from different organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200852"} {"pmid": "4200854", "title": "Regulation of leucine biosynthesis in Bacillus subtilis.", "content": "Regulation of leucine biosynthesis in Bacillus subtilis. The biosynthesis of alpha-isopropylmalate (alphaIPM) synthetase, IPM isomerase, and betaIPM dehydrogenase in Bacillus subtilis can be derepressed in leucine auxotrophs by limiting them for leucine. The derepression of the three enzymes is apparently coordinate. A class of mutants resistant to 4-azaleucine excretes leucine and has derepressed levels of all three enzymes. The azaleucine-resistance mutations may lie in a gene (azlA) encoding a repressor. Efforts to find mutations characteristic of a constitutive operator have been unsuccessful. No polar mutations have been found among nine leucine auxotrophs that have characteristics of frameshift mutations. The enzyme catalyzing the first step in leucine biosynthesis, alphaIPM synthetase, is sensitive to feedback inhibition by leucine. We conclude that leucine biosynthesis is controlled by the inhibition of the activity of the first biosynthetic enzyme by leucine, and by the repression of the synthesis of the first three biosynthetic enzymes by leucine. The repression of the three enzymes may be under the control of a single repressor and a single operator, or of a single repressor and a separate operator for each structural gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200854"} {"pmid": "4200855", "title": "Synchronous cultures of Bacillus subtilis obtained by filtration with glass fiber filters.", "content": "Synchronous cultures of Bacillus subtilis obtained by filtration with glass fiber filters. A simple method of potentially wide applicability for obtaining synchronous cultures of Bacillus subtilis based on size selection is described. Using glass fiber filters, a population (about 1 to 2% of the parent population) can be obtained substantially enriched for small cells which grow synchronously. A method for rapidly concentrating dilute suspensions of cells is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200855"} {"pmid": "4200856", "title": "Defined physiological conditions for the induction of the L-form of Neisseria gonorrhoeae.", "content": "Defined physiological conditions for the induction of the L-form of Neisseria gonorrhoeae. Defined conditions are described which allowed luxuriant growth over continuous subculture of strains of Neisseria gonorrhoeae in broth and on agar. Growth was equal to or surpassed that observed in Mueller-Hinton broth or on Mueller-Hinton blood agar. The final medium adopted consisted of medium 199 and a supplemental mixture of cysteine, glucose, and various salts. Addition of sodium bicarbonate or CO(2) enrichment was not required. For solidification, only agarose allowed growth of all strains; glutamic acid stimulated growth of two strains but was inhibitory for a third. The addition of 8% polyvinylpyrrolidone (PVP), 2% purified albumin, and penicillin resulted in induction of all three strains to the L-form with frequencies up to 0.3%. At present no induction to the L-form has been achieved in the absence of albumin. Various lots of PVP proved toxic in the defined medium, and extensive dialysis was required for good growth and L-form induction. Substitution of PVP with sucrose indicated a sucrose toxicity for the parental gonococcus even on the addition of albumin. L-form induction did occur on sucrose L-medium but at significantly lower frequencies. The colonies appeared 1 week later than those on PVP L-medium but at significantly lower frequencies. The colonies appeared 1 week later than those on PVP L-medium and remained very small and poorly developed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200856"} {"pmid": "4200857", "title": "Germination of Bacillus megaterium spores after various extraction procedures.", "content": "Germination of Bacillus megaterium spores after various extraction procedures. The initiation of germination of Bacillus megaterium QM B1551 spores, grown in supplemented nutrient broth, has been studied. The initiation properties depend on buffer concentrations and the particular batch of spores. Initiation in l-alanine, KBr, calcium dipicolinate, or in buffer alone increases as a function of the spore age; whereas initiation in glucose, l-leucine, or l-proline remains relatively constant. Extraction of spores with alkali, sodium dodecyl sulfate-dithiothreitol, or lithium diiodosalicylate removes variable amounts of dipicolinic acid, hexosamine, and protein. These extracted spores are still capable of initiation and, in some cases, initiation is stimulated. However, extraction of spores with 8 M urea-10% mercaptoethanol inhibits subsequent initiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200857"} {"pmid": "4200858", "title": "Development of ultraviolet resistance in sporulating Bacillus cereus T.", "content": "Development of ultraviolet resistance in sporulating Bacillus cereus T. Ultraviolet (UV) resistance patterns of sporulating Bacillus cereus were determined. Six different categories of UV resistance were discernible as the organism progressed from exponential growth to the free, mature spore. Light microscope observations allowed the assignment of certain sporulation stages to specific UV resistance categories. Marked changes in UV resistance were associated with stages III, mid-IV, and post-IV of sporulation. Dipicolinic acid was shown to sensitize forespores to UV radiation. Mechanisms invoked to explain the different UV categories are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200858"} {"pmid": "4200859", "title": "Growth properties of Rhodospirillum rubrum mutants and fermentation of pyruvate in anaerobic, dart conditions.", "content": "Growth properties of Rhodospirillum rubrum mutants and fermentation of pyruvate in anaerobic, dart conditions. Mutant C and G1 were obtained earlier from Rhodospirillum rubrum S(1) during growth in the dark under strict anaerobic conditions in medium containing sodium pyruvate. Mutant C and mutant G1 grew in the dark with generation times of 5.8 h and 4.6 h, respectively. Mutant C cells grew equally well when switched between anaerobic (dark or light) or aerobic, dark conditions. Mutant G1 cells grew only in the dark (anaerobic or aerobic conditions), but a fraction of cells in anaerobic, dark cultures grew when placed in light. This number increased about 3,000-fold when G1 cells were incubated aerobically in the dark. During anaerobic, dark growth, C and G1 organisms incorporated similar amounts of [2-(14)C]sodium pyruvate. About 34% of the incorporated radioactivity was found in lipid fractions from C cells that developed chromatophores during dark growth. Similar results were obtained using G1 cells, which formed only trace amounts of photosynthetic structures. Both mutants fermented sodium pyruvate and produced acetate, formate, carbon dioxide, and hydrogen gas. Molar growth yield coefficients indicated that the cells obtained about 1 mol of adenosine triphosphate per mol of sodium pyruvate fermented. Results suggested that pyruvate fermentation during dark growth occurred via a pyruvate formate-lyase or the pyruvate ferredoxin-oxidoreductase pathway, or both.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200859"} {"pmid": "4200860", "title": "Production and characterization of the slime polysaccharide of Pseudomonas aeruginosa.", "content": "Production and characterization of the slime polysaccharide of Pseudomonas aeruginosa. The slime polysaccharides produced by Pseudomonas aeruginosa isolated from a variety of human infections were investigated. Slime production in culture seemed optimal when adequate amounts of carbohydrate were present and under conditions of either high osmotic pressure or inadequate protein supply. The polysaccharides produced by the organisms were similar to each other, to the slime of Azotobacter vinelandii, and to seaweed alginic acids. They were composed of beta-1,4-linked d-mannuronic acid residues and variable amounts of its 5-epimer l-guluronic acid. All bacterial polymers contained o-acetyl groups which are absent in the alginates. The polysaccharides differed considerably in the ratio of mannuronic to guluronic acid content and in the number of o-acetyl groups. The particular composition of the slime was not found to be characteristic for the disease process from which the mucoid variants of P. aeruginosa were obtained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200860"} {"pmid": "4200861", "title": "Effects of leucine starvation on control of ribonucleic acid synthesis in strains of Bacillus subtilis differing in deoxyribonucleic acid regulation.", "content": "Effects of leucine starvation on control of ribonucleic acid synthesis in strains of Bacillus subtilis differing in deoxyribonucleic acid regulation. When starved for leucine, strains of Bacillus subtilis do not complete chromosome replication to the terminus. The amount of deoxyribonucleic acid (DNA) made poststarvation is characteristic of the strain. In this study, four strains differing in their DNA response were examined for ribonucleic acid (RNA) regulation during leucine starvation. Each of the strains was judged to be stringent for RNA control based on the amount of RNA made poststarvation. Sucrose gradient profiles on RNA made with and without leucine starvation support this conclusion. Accumulation of guanosine tetraphosphate during leucine starvation showed no correlation with the amount of DNA synthesized. We concluded that modulation control of DNA synthesis during leucine starvation is independent of RNA control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200861"} {"pmid": "4200862", "title": "New method for the isolation of membranes from Mycoplasma gallisepticum.", "content": "New method for the isolation of membranes from Mycoplasma gallisepticum. Mycoplasma gallisepticum lysed readily in carbonate bicarbonate buffer at pH 9.2 to 10.5. The hemagglutination titer of the lysates was 2- to 16-fold greater than a cell suspension at the same protein concentration in buffered saline. Membranes prepared from cells lysed by this method at pH 10 were relatively free from cytoplasmic contaminants as shown by electron microscopy of thin sections. The membranes retained their hemagglutination activity, gave reactions in immunodiffusion tests identical to those obtained by osmotic lysis and sonic treatment, and showed a similar pattern of protein bands by polyacrylamide disk electrophoresis. When inoculated into rabbits, the membranes gave rise to antibodies active in growth-, metabolic- and hemagglutination-inhibition tests. On the average, membranes obtained by lysis at pH 10 contained 44% of the original cell protein. The method is simple, giving high yields of membranes, and may be adaptable to other mycoplasmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200862"} {"pmid": "4200863", "title": "Ascorbate oxidase. Further studies on the purification of the enzyme.", "content": "Ascorbate oxidase. Further studies on the purification of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200863"} {"pmid": "4200864", "title": "D-alanine carboxypeptidase from Bacillus subtilis membranes. I. Purification and characterization.", "content": "D-alanine carboxypeptidase from Bacillus subtilis membranes. I. Purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200864"} {"pmid": "4200865", "title": "D-alanine carboxypeptidase from Bacillus subtilis membranes. II. Interaction with penicillins and cephalosporins.", "content": "D-alanine carboxypeptidase from Bacillus subtilis membranes. II. Interaction with penicillins and cephalosporins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200865"} {"pmid": "4200866", "title": "The biosynthesis of unsaturated fatty acids by bacilli. V. In vivo substrate specificities of fatty acid desaturases.", "content": "The biosynthesis of unsaturated fatty acids by bacilli. V. In vivo substrate specificities of fatty acid desaturases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200866"} {"pmid": "4200867", "title": "Effect of diamide on growth of selected bacteria.", "content": "Effect of diamide on growth of selected bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200867"} {"pmid": "4200868", "title": "Serum \"beta 1A\" levels in older humans.", "content": "Serum \"beta 1A\" levels in older humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200868"} {"pmid": "4200870", "title": "Gastrostomy in laryngology.", "content": "Gastrostomy in laryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200870"} {"pmid": "4200871", "title": "Synthetic penicillins. Heterocyclic analogs of ampicillin. Structure-activity relationships.", "content": "Synthetic penicillins. Heterocyclic analogs of ampicillin. Structure-activity relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200871"} {"pmid": "4200872", "title": "Metabolism of aspartame in monkeys.", "content": "Metabolism of aspartame in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200872"} {"pmid": "4200873", "title": "Effect of aspartame on phenylalanine metabolism in the monkey.", "content": "Effect of aspartame on phenylalanine metabolism in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200873"} {"pmid": "4200874", "title": "Relationship of C-reactive protein in autologous plasma of cancer patients and choline phosphate in lymphocyte responses to phytohemagglutinin.", "content": "Relationship of C-reactive protein in autologous plasma of cancer patients and choline phosphate in lymphocyte responses to phytohemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200874"} {"pmid": "4200875", "title": "Erythromycin therapy twice daily for streptococcal pharyngitis. Controlled comparison with erythromycin or penicillin phenoxymethyl four times daily or penicillin G benzathine.", "content": "Erythromycin therapy twice daily for streptococcal pharyngitis. Controlled comparison with erythromycin or penicillin phenoxymethyl four times daily or penicillin G benzathine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200875"} {"pmid": "4200869", "title": "Habitat selection in experimental populations of Drosophila melanogaster.", "content": "Habitat selection in experimental populations of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200869"} {"pmid": "4200876", "title": "In vitro activity of carbenicillin against Pseudomonas using the disc diffusion method.", "content": "In vitro activity of carbenicillin against Pseudomonas using the disc diffusion method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200876"} {"pmid": "4200877", "title": "Accumulation of hepatic mitochondria in 2-methyl-4-dimethyl-aminoazobenzene fed rats as a result of decreased degradation.", "content": "Accumulation of hepatic mitochondria in 2-methyl-4-dimethyl-aminoazobenzene fed rats as a result of decreased degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200877"} {"pmid": "4200879", "title": "Editorial: Get in there and replant.", "content": "Editorial: Get in there and replant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200879"} {"pmid": "4200880", "title": "Vasopressin and neurophysin: high concentrations in monkey hypophyseal portal blood.", "content": "Vasopressin and neurophysin: high concentrations in monkey hypophyseal portal blood. Vasopressin and its binding protein, neurophysin, were measured by radioimmunoassay in the hypophyseal portal blood of monkeys after cannulation of individual long portal veins. Mean vasopressin concentrations (13,800 picograms per milliliter) in portal blood were more than 300 times as high as those in the systemic circulation (42 picograms per milliliter). Neurophysin concentration was approximately 25 times as high in portal as in systemic blood. By immunoperoxidase techniques, high concentrations of neurophysin were demonstrated around portal capillaries of the median eminence. These studies indicate direct secretion of vasopressin and neurophysin into the portal circulation; the quantities secreted during stress may be sufficient to exert significant effects on secretion of anterior pituitary hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200880"} {"pmid": "4200881", "title": "Proteins induced in Bacillus subtilis infected with bacteriophage phi 29.", "content": "Proteins induced in Bacillus subtilis infected with bacteriophage phi 29.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200881"} {"pmid": "4200882", "title": "Presence of antibodies to double-stranded RNA in sera of rabbits immunized with rice dwarf and maize rough dwarf viruses.", "content": "Presence of antibodies to double-stranded RNA in sera of rabbits immunized with rice dwarf and maize rough dwarf viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200882"} {"pmid": "4200883", "title": "Japanese encephalitis virus glycoproteins.", "content": "Japanese encephalitis virus glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200883"} {"pmid": "4200884", "title": "Protein synthesis in Japanese encephalitis virus-infected cells.", "content": "Protein synthesis in Japanese encephalitis virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200884"} {"pmid": "4200885", "title": "Serum LH during ovulatory and anovulatory menstrual cycles in macaques.", "content": "Serum LH during ovulatory and anovulatory menstrual cycles in macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200885"} {"pmid": "4200886", "title": "A cross-species comparison of status in small established groups.", "content": "A cross-species comparison of status in small established groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200886"} {"pmid": "4200888", "title": "Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine (ARA-C) deamination in several species.", "content": "Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine (ARA-C) deamination in several species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200888"} {"pmid": "4200889", "title": "Homoserine dehydrogenase of Rhodospirillum rubrum. Enzyme polymerization in the presence and absence of threonine.", "content": "Homoserine dehydrogenase of Rhodospirillum rubrum. Enzyme polymerization in the presence and absence of threonine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200889"} {"pmid": "4200887", "title": "Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa.", "content": "Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200887"} {"pmid": "4200890", "title": "Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases.", "content": "Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200890"} {"pmid": "4200891", "title": "Lactate dehydrogenase isozymes. Turnover in rat heart, skeletal muscle, and liver.", "content": "Lactate dehydrogenase isozymes. Turnover in rat heart, skeletal muscle, and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200891"} {"pmid": "4200892", "title": "Effects of metals on the properties of hepatic microsomal uridine diphosphate glucuronyltransferase.", "content": "Effects of metals on the properties of hepatic microsomal uridine diphosphate glucuronyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200892"} {"pmid": "4200893", "title": "Evolutionary stability of the histone genes of sea urchins.", "content": "Evolutionary stability of the histone genes of sea urchins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200893"} {"pmid": "4200896", "title": "Carbon monoxide production from hydroxocobalamin by bacteria.", "content": "Carbon monoxide production from hydroxocobalamin by bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200896"} {"pmid": "4200894", "title": "Quenching of protein fluorescence by oxygen. Detection of structural fluctuations in proteins on the nanosecond time scale.", "content": "Quenching of protein fluorescence by oxygen. Detection of structural fluctuations in proteins on the nanosecond time scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200894"} {"pmid": "4200913", "title": "Interrelation of the urinary trypsin inhibitor to human plasma inter-alpha-trypsin inhibitor.", "content": "Interrelation of the urinary trypsin inhibitor to human plasma inter-alpha-trypsin inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200913"} {"pmid": "4200914", "title": "The acyl-carrier protein of citrate lyase.", "content": "The acyl-carrier protein of citrate lyase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200914"} {"pmid": "4200916", "title": "An unusual type of bacterial cell-wall in a mutant of Bacillus subtilis 168.", "content": "An unusual type of bacterial cell-wall in a mutant of Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200916"} {"pmid": "4200915", "title": "On the reconstitution of photophosphorylation in chloroplast membranes.", "content": "On the reconstitution of photophosphorylation in chloroplast membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200915"} {"pmid": "4200917", "title": "Studies on the sensitization of animals with simple chemical compounds. XIV. Further studies on sensitization of guinea pigs with picric acid.", "content": "Studies on the sensitization of animals with simple chemical compounds. XIV. Further studies on sensitization of guinea pigs with picric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200917"} {"pmid": "4200918", "title": "Systemic and urinary immune response in experimental E. coli pyelonephritis of mice.", "content": "Systemic and urinary immune response in experimental E. coli pyelonephritis of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200918"} {"pmid": "4200919", "title": "Skin reactions induced by sera of patients with monoclonal IgG gammapathy.", "content": "Skin reactions induced by sera of patients with monoclonal IgG gammapathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200919"} {"pmid": "4200921", "title": "Sterilization of anesthesia apparatus.", "content": "Sterilization of anesthesia apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200921"} {"pmid": "4200922", "title": "Glycosphingolipids of membrane fractions from normal and transplanted canine kidney.", "content": "Glycosphingolipids of membrane fractions from normal and transplanted canine kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200922"} {"pmid": "4200923", "title": "Deoxyribonucleic acid synthesis in bacteriophage SP01-infected Bacillus subtilis. II. Purification and catalytic properties of a deoxyribonucleic acid polymerase induced after infection.", "content": "Deoxyribonucleic acid synthesis in bacteriophage SP01-infected Bacillus subtilis. II. Purification and catalytic properties of a deoxyribonucleic acid polymerase induced after infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200923"} {"pmid": "4200924", "title": "Proteolytic conversion of the molecular forms of bovine milk galactosyltransferase.", "content": "Proteolytic conversion of the molecular forms of bovine milk galactosyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200924"} {"pmid": "4200926", "title": "Effects of castration and replacement therapy on sexual behavior of adult male rhesuses.", "content": "Effects of castration and replacement therapy on sexual behavior of adult male rhesuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200926"} {"pmid": "4200925", "title": "Chromatographic behaviour of mouse spleen cells on glass bead columns.", "content": "Chromatographic behaviour of mouse spleen cells on glass bead columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200925"} {"pmid": "4200927", "title": "Avoidance learning in phenylketonuric monkeys.", "content": "Avoidance learning in phenylketonuric monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200927"} {"pmid": "4200928", "title": "Visual sensitivity following inferotemporal and foveal prestriate lesions in the rhesus monkey.", "content": "Visual sensitivity following inferotemporal and foveal prestriate lesions in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200928"} {"pmid": "4200929", "title": "Pteridines. 2. New 6,7-disubstituted pteridines as potential antimalarial and antitumor agents.", "content": "Pteridines. 2. New 6,7-disubstituted pteridines as potential antimalarial and antitumor agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200929"} {"pmid": "4200930", "title": "Metastable secondary structures in ribosomal RNA molecular hysteresis in the acid-base titration of Escherichia coli ribosomal RNA.", "content": "Metastable secondary structures in ribosomal RNA molecular hysteresis in the acid-base titration of Escherichia coli ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200930"} {"pmid": "4200931", "title": "Effects of pollution on freshwater fish.", "content": "Effects of pollution on freshwater fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200931"} {"pmid": "4200933", "title": "Biologic aspects of endodontics. V. Periapical tissue reactions to root canal instrumentation beyond the apex and root canal fillings short of and beyond the apex.", "content": "Biologic aspects of endodontics. V. Periapical tissue reactions to root canal instrumentation beyond the apex and root canal fillings short of and beyond the apex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200933"} {"pmid": "4200937", "title": "T3 thyrotoxicosis.", "content": "T3 thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200937"} {"pmid": "4200938", "title": "Gout.", "content": "Gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200938"} {"pmid": "4200940", "title": "The cerebrospinal fluid in uncontrolled diabetes mellitus.", "content": "The cerebrospinal fluid in uncontrolled diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200940"} {"pmid": "4200939", "title": "Determination of revised Air Force permissible exposure levels for laser radiation.", "content": "Determination of revised Air Force permissible exposure levels for laser radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200939"} {"pmid": "4200955", "title": "Immunologic studies of antihemophilic factor (AHF, factor VIII). V. Immunologic properties of AHF subunits produced by salt dissociation.", "content": "Immunologic studies of antihemophilic factor (AHF, factor VIII). V. Immunologic properties of AHF subunits produced by salt dissociation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200955"} {"pmid": "4200954", "title": "Bilateral meningococcal endophthalmitis.", "content": "Bilateral meningococcal endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200954"} {"pmid": "4200956", "title": "Lymphocytes forming red cell rosettes in the cold in patients with chronic cold agglutinin disease.", "content": "Lymphocytes forming red cell rosettes in the cold in patients with chronic cold agglutinin disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200956"} {"pmid": "4200957", "title": "Patterns of new chronicity in a mental hospital.", "content": "Patterns of new chronicity in a mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200957"} {"pmid": "4200958", "title": "Editorial: Smallpox eradication.", "content": "Editorial: Smallpox eradication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200958"} {"pmid": "4200959", "title": "Indwelling catheter infection.", "content": "Indwelling catheter infection. A \"catheter team\", consisting of two hospital assistants specially trained to catheterize male patients, inserted indwelling catheters in 435 men over a two-year period. The infection rate was 33%; in the 200 patients not treated with antimicrobial drugs (study group) the rate was 37%, while in the 235 patients who were so treated (antibacterial group) the infection rate was 29%. Fifty percent of patients not treated were infected after 6.3 days, whereas in patients on antibacterial therapy a 50% infection rate was not reached until 14 days after insertion. Therefore, no antibacterial therapy is necessary if it is anticipated that the catheter will be necessary for less than four days. On the other hand, prophylactic antibacterial therapy would delay the onset of infection considerably if catheterization were expected to continue for more than four days. Sulfisoxazole was our drug of choice for prophylactic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200959"} {"pmid": "4200971", "title": "[Report on the use of a portable gas-cooling ophthalmic cryo-coagulator].", "content": "[Report on the use of a portable gas-cooling ophthalmic cryo-coagulator].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200971"} {"pmid": "4200974", "title": "Experimental infective pneumoconiosis: effect of asbestos dust and Candida albicans infection on the lungs of rhesus monkeys.", "content": "Experimental infective pneumoconiosis: effect of asbestos dust and Candida albicans infection on the lungs of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200974"} {"pmid": "4200975", "title": "Function of adrenal gland-zona fasciculata in rats receiving polychlorinated biphenyls.", "content": "Function of adrenal gland-zona fasciculata in rats receiving polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200975"} {"pmid": "4200976", "title": "Modulation of masseteric and digastric neural activity by stimulation of the dorsolateral cerebral cortex in the squirrel monkey.", "content": "Modulation of masseteric and digastric neural activity by stimulation of the dorsolateral cerebral cortex in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200976"} {"pmid": "4200977", "title": "Spinal and cortical inhibition of intestinal motility in the squirrel monkey.", "content": "Spinal and cortical inhibition of intestinal motility in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200977"} {"pmid": "4200986", "title": "A comparative study of isocyclic hydrocarbons in animals and in man.", "content": "A comparative study of isocyclic hydrocarbons in animals and in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200986"} {"pmid": "4200989", "title": "Disposition of clonixin (2-(3-chloro-o-toluidino) nicotinic acid) in humans.", "content": "Disposition of clonixin (2-(3-chloro-o-toluidino) nicotinic acid) in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200989"} {"pmid": "4200990", "title": "A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self-administration in cocaine-dependent rhesus monkeys.", "content": "A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self-administration in cocaine-dependent rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200990"} {"pmid": "4200991", "title": "Delayed repair of esophageal atresia with T-E fistula in two premature infants. Use of a jejunostomy as an alternative to intravenous alimentation.", "content": "Delayed repair of esophageal atresia with T-E fistula in two premature infants. Use of a jejunostomy as an alternative to intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200991"} {"pmid": "4200994", "title": "Embryo transfer and sensitivity to teratogenesis.", "content": "Embryo transfer and sensitivity to teratogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200994"} {"pmid": "4200995", "title": "Enhancement of metabolic coronary dilatation by aspirin-like substances by suppression of prostaglandin feedback control?", "content": "Enhancement of metabolic coronary dilatation by aspirin-like substances by suppression of prostaglandin feedback control?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200995"} {"pmid": "4200996", "title": "Further investigations into the teratogenic potential of imperfect potatoes.", "content": "Further investigations into the teratogenic potential of imperfect potatoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200996"} {"pmid": "4200997", "title": "Multivariate analysis of the Dryopithecus africanus forelimb.", "content": "Multivariate analysis of the Dryopithecus africanus forelimb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200997"} {"pmid": "4200998", "title": "Intracranial mycotic aneurysms and subacute bacterial endocarditis in heroin addiction.", "content": "Intracranial mycotic aneurysms and subacute bacterial endocarditis in heroin addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200998"} {"pmid": "4200999", "title": "Brain abscess from septic cerebral embolism: an experimental model.", "content": "Brain abscess from septic cerebral embolism: an experimental model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4200999"} {"pmid": "4201001", "title": "Experience in the treatment of hepatic failure by intermittent liver hemoperfusions.", "content": "Experience in the treatment of hepatic failure by intermittent liver hemoperfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201001"} {"pmid": "4201002", "title": "Impaired function of polymorphonuclear leukocytes in patients with burns and other trauma.", "content": "Impaired function of polymorphonuclear leukocytes in patients with burns and other trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201002"} {"pmid": "4201003", "title": "Experience with intensive surveillance of urinary tract infection.", "content": "Experience with intensive surveillance of urinary tract infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201003"} {"pmid": "4201004", "title": "Triglyceride and free fatty acid clearances in patients receiving complete parenteral nutrition using a ten per cent soybean oil emulsion.", "content": "Triglyceride and free fatty acid clearances in patients receiving complete parenteral nutrition using a ten per cent soybean oil emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201004"} {"pmid": "4201005", "title": "Prevention of postoperative intestinal adhesions in primates.", "content": "Prevention of postoperative intestinal adhesions in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201005"} {"pmid": "4201006", "title": "A kwashiorkor-like syndrome in hospitalized patients.", "content": "A kwashiorkor-like syndrome in hospitalized patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201006"} {"pmid": "4201007", "title": "Effect of treatment on the development of vascular lesions in the hypertensive rat.", "content": "Effect of treatment on the development of vascular lesions in the hypertensive rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201007"} {"pmid": "4201008", "title": "Undifferentiated mononuclear cell in human embryonic liver; presumptive hematopoietic stem cell.", "content": "Undifferentiated mononuclear cell in human embryonic liver; presumptive hematopoietic stem cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201008"} {"pmid": "4201010", "title": "Morphological modifications of the frog bladder induced by non ionic detergents (Rana pipiens L.).", "content": "Morphological modifications of the frog bladder induced by non ionic detergents (Rana pipiens L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201010"} {"pmid": "4201012", "title": "Microbody (peroxisome) matrix: transformation into tubular structures.", "content": "Microbody (peroxisome) matrix: transformation into tubular structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201012"} {"pmid": "4201013", "title": "Total intravenous alimentation.", "content": "Total intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201013"} {"pmid": "4201014", "title": "Antibiotic usage and microbial resistance in an intensive care nursery.", "content": "Antibiotic usage and microbial resistance in an intensive care nursery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201014"} {"pmid": "4201015", "title": "Immunologic significance of aspergillin antigens of six species of Aspergillus in the serodiagnosis of aspergillosis.", "content": "Immunologic significance of aspergillin antigens of six species of Aspergillus in the serodiagnosis of aspergillosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201015"} {"pmid": "4201016", "title": "Nosocomial pneumonia. A continuing major problem.", "content": "Nosocomial pneumonia. A continuing major problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201016"} {"pmid": "4201017", "title": "Response of Mycobacteria to ultraviolet light radiation.", "content": "Response of Mycobacteria to ultraviolet light radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201017"} {"pmid": "4201018", "title": "Immunoelectrophoretic analysis of antigenic constituents of Seibert fractions of mycobacterial culture filtrates. Identification with the proposed United States-Japan reference nomenclature.", "content": "Immunoelectrophoretic analysis of antigenic constituents of Seibert fractions of mycobacterial culture filtrates. Identification with the proposed United States-Japan reference nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201018"} {"pmid": "4201019", "title": "The labeling of nucleic acids by radioactive precursors in the blue-green algae Anacystis nidulans and Synechocystis aquatilis Sanv.", "content": "The labeling of nucleic acids by radioactive precursors in the blue-green algae Anacystis nidulans and Synechocystis aquatilis Sanv.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201019"} {"pmid": "4201020", "title": "The pathway of carbon dioxide assimilation in Rhodospirillum rubrum grown in turbidostat continuous-flow culture.", "content": "The pathway of carbon dioxide assimilation in Rhodospirillum rubrum grown in turbidostat continuous-flow culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201020"} {"pmid": "4201021", "title": "Optics and visual physiology.", "content": "Optics and visual physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201021"} {"pmid": "4201024", "title": "Experimental protein-energy malnutrition in baby baboons. 2. Liver pathology.", "content": "Experimental protein-energy malnutrition in baby baboons. 2. Liver pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201024"} {"pmid": "4201025", "title": "Rate of passage of digesta in sheep. 3. Differential rates of passage of water and dry matter from the reticulo-rumen, abomasum and caecum and proximal colon.", "content": "Rate of passage of digesta in sheep. 3. Differential rates of passage of water and dry matter from the reticulo-rumen, abomasum and caecum and proximal colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201025"} {"pmid": "4201026", "title": "Comparison of the development of proteolytic activity in the abomasum of the preruminant calf with that in the stomach of the young rabbit and guinea-pig.", "content": "Comparison of the development of proteolytic activity in the abomasum of the preruminant calf with that in the stomach of the young rabbit and guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201026"} {"pmid": "4201027", "title": "Rate of passage of digesta in sheep. 4. Passage of marker through the alimentary tract and the biological relevance of rate-constants derived from the changes in concentration of marker in faeces.", "content": "Rate of passage of digesta in sheep. 4. Passage of marker through the alimentary tract and the biological relevance of rate-constants derived from the changes in concentration of marker in faeces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201027"} {"pmid": "4201028", "title": "Circulating \"big\" insulin in protein-energy malnutrition.", "content": "Circulating \"big\" insulin in protein-energy malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201028"} {"pmid": "4201032", "title": "Evaluation of several geometric models for estimation of left ventricular circumferential wall stress.", "content": "Evaluation of several geometric models for estimation of left ventricular circumferential wall stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201032"} {"pmid": "4201031", "title": "Detection of collagen degradation products in bone.", "content": "Detection of collagen degradation products in bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201031"} {"pmid": "4201033", "title": "Cardiovascular and metabolic effects of whole or fractionated gram-negative bacterial endotoxin in the unanesthetized Rhesus monkey.", "content": "Cardiovascular and metabolic effects of whole or fractionated gram-negative bacterial endotoxin in the unanesthetized Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201033"} {"pmid": "4201035", "title": "Suggestions for economic survival.", "content": "Suggestions for economic survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201035"} {"pmid": "4201034", "title": "Enzyme-linked immunoassay for alpha-fetoprotein by competitive and sandwich procedures.", "content": "Enzyme-linked immunoassay for alpha-fetoprotein by competitive and sandwich procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201034"} {"pmid": "4201036", "title": "Serum immunoglobulin levels in farmer's lung disease.", "content": "Serum immunoglobulin levels in farmer's lung disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201036"} {"pmid": "4201037", "title": "Platelet factor 4--antiheparin protein releasable from platelets. Purification and properties.", "content": "Platelet factor 4--antiheparin protein releasable from platelets. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201037"} {"pmid": "4201038", "title": "The effect of amino acid solutions of differing composition on the nitrogen balance of postoperative patients.", "content": "The effect of amino acid solutions of differing composition on the nitrogen balance of postoperative patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201038"} {"pmid": "4201029", "title": "Comparison of final filtration devices.", "content": "Comparison of final filtration devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201029"} {"pmid": "4201039", "title": "Acute forms of tuberculosis.", "content": "Acute forms of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201039"} {"pmid": "4201040", "title": "Evaluation of acute chest pain.", "content": "Evaluation of acute chest pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201040"} {"pmid": "4201030", "title": "Drug additive compatibility--a manufacturer's concern.", "content": "Drug additive compatibility--a manufacturer's concern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201030"} {"pmid": "4201042", "title": "Pleiotropic nature of bacteriophage tolerant mutants obtained in early-blocked asporogenous mutants of Bacillus subtilis 168.", "content": "Pleiotropic nature of bacteriophage tolerant mutants obtained in early-blocked asporogenous mutants of Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201042"} {"pmid": "4201043", "title": "Demonstration of Aleutian mink disease virus in cell culture.", "content": "Demonstration of Aleutian mink disease virus in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201043"} {"pmid": "4201044", "title": "The effects of polychlorinated biphenyl on longevity of bobwhite quail (Collinus virginianus): a sex differential.", "content": "The effects of polychlorinated biphenyl on longevity of bobwhite quail (Collinus virginianus): a sex differential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201044"} {"pmid": "4201045", "title": "Experimental emphysema in rats: elastolytic titer of inducing enzyme as determinant of the response.", "content": "Experimental emphysema in rats: elastolytic titer of inducing enzyme as determinant of the response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201045"} {"pmid": "4201047", "title": "In vivo stimulation of prolactin release in the rat by synthetic TRH.", "content": "In vivo stimulation of prolactin release in the rat by synthetic TRH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201047"} {"pmid": "4201048", "title": "Structure and biologic functions of human IgD. II. Alteration of serum IgD levels during pregnancy.", "content": "Structure and biologic functions of human IgD. II. Alteration of serum IgD levels during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201048"} {"pmid": "4201046", "title": "Solubilization and purification of human erythrocyte membrane acetylcholinesterase.", "content": "Solubilization and purification of human erythrocyte membrane acetylcholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201046"} {"pmid": "4201050", "title": "Teratogenic effects of carcinogen implantation in a regenerative field in Bufo arenarum tadpoles.", "content": "Teratogenic effects of carcinogen implantation in a regenerative field in Bufo arenarum tadpoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201050"} {"pmid": "4201052", "title": "Nourishing the solute-sensitive patient.", "content": "Nourishing the solute-sensitive patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201052"} {"pmid": "4201053", "title": "Immunological responses in the mole rat (Spalax leucodon). II. Serum proteins of nonimmunized mole rats.", "content": "Immunological responses in the mole rat (Spalax leucodon). II. Serum proteins of nonimmunized mole rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201053"} {"pmid": "4201056", "title": "Humoral autoimmune response against rabbit male accessory glands elicited by untreated and chemically modified rabbit seminal plasma.", "content": "Humoral autoimmune response against rabbit male accessory glands elicited by untreated and chemically modified rabbit seminal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201056"} {"pmid": "4201057", "title": "Distribution of tubercle bacilli with various degrees of drug-resistance in the organs of guinea pigs.", "content": "Distribution of tubercle bacilli with various degrees of drug-resistance in the organs of guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201057"} {"pmid": "4201059", "title": "Absence of correlation between haemolysing splenic cell numbers and resistance to cancer induction by methylcholanthrene.", "content": "Absence of correlation between haemolysing splenic cell numbers and resistance to cancer induction by methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201059"} {"pmid": "4201060", "title": "Physicochemical studies of microbial cell walls. I. Comparative electrophoretic behavior of intact cells and isolated cell walls.", "content": "Physicochemical studies of microbial cell walls. I. Comparative electrophoretic behavior of intact cells and isolated cell walls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201060"} {"pmid": "4201049", "title": "Present status of one-stage pharyngo-esophageal diverticulectomy.", "content": "Present status of one-stage pharyngo-esophageal diverticulectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201049"} {"pmid": "4201061", "title": "Identification of presumptive histone messenger RNA in rapidly labelled polysomal RNA of mouse myelomas.", "content": "Identification of presumptive histone messenger RNA in rapidly labelled polysomal RNA of mouse myelomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201061"} {"pmid": "4201062", "title": "Regulation of pancreatic alpha-amylase in the neonatal mouse.", "content": "Regulation of pancreatic alpha-amylase in the neonatal mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201062"} {"pmid": "4201063", "title": "Perinatal brain damage: porencephaly in a cynomolgous monkey.", "content": "Perinatal brain damage: porencephaly in a cynomolgous monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201063"} {"pmid": "4201064", "title": "Characterization of newborn leukocyte alkaline phosphatase.", "content": "Characterization of newborn leukocyte alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201064"} {"pmid": "4201065", "title": "Intrauterine pneumonia. An experimental study.", "content": "Intrauterine pneumonia. An experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201065"} {"pmid": "4201067", "title": "The occurrence of anterior open bites in captive- and wild-born monkeys (Macaca fascicularis).", "content": "The occurrence of anterior open bites in captive- and wild-born monkeys (Macaca fascicularis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201067"} {"pmid": "4201066", "title": "Protein and nucleic acid metabolism in insect fat body.", "content": "Protein and nucleic acid metabolism in insect fat body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201066"} {"pmid": "4201068", "title": "Electrophoretic and antigenic properties of turtle myoglobins.", "content": "Electrophoretic and antigenic properties of turtle myoglobins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201068"} {"pmid": "4201069", "title": "Genetic programming for development in Drosophila.", "content": "Genetic programming for development in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201069"} {"pmid": "4201073", "title": "The politics of developing a national health policy.", "content": "The politics of developing a national health policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201073"} {"pmid": "4201075", "title": "Health care in the United States: who pays?", "content": "Health care in the United States: who pays?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201075"} {"pmid": "4201074", "title": "Resource allocation, equality of access, and health.", "content": "Resource allocation, equality of access, and health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201074"} {"pmid": "4201076", "title": "The origins of health insurance for the aged.", "content": "The origins of health insurance for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201076"} {"pmid": "4201077", "title": "More money into the medical sector: is this the answer?", "content": "More money into the medical sector: is this the answer?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201077"} {"pmid": "4201078", "title": "Ontogeny and localization of the crystallins during embryonic lens development in Xenopus laevis.", "content": "Ontogeny and localization of the crystallins during embryonic lens development in Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201078"} {"pmid": "4201070", "title": "Allergens from short ragweed leaf tissue cultures.", "content": "Allergens from short ragweed leaf tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201070"} {"pmid": "4201072", "title": "Isolation and growth characteristics of cell lines from bovine venous endothelium.", "content": "Isolation and growth characteristics of cell lines from bovine venous endothelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201072"} {"pmid": "4201079", "title": "A serologic comparison of bat complements.", "content": "A serologic comparison of bat complements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201079"} {"pmid": "4201080", "title": "Quantitative variation in erythrocyte enzymes of the pig-tailed macaque, Macaca nemestrina.", "content": "Quantitative variation in erythrocyte enzymes of the pig-tailed macaque, Macaca nemestrina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201080"} {"pmid": "4201082", "title": "Ectopic splenic nodules in the pancreas of a capuchin monkey (Cebus albifrons).", "content": "Ectopic splenic nodules in the pancreas of a capuchin monkey (Cebus albifrons).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201082"} {"pmid": "4201081", "title": "Nosematosis in a squirrel monkey (Saimiri sciureus).", "content": "Nosematosis in a squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201081"} {"pmid": "4201071", "title": "Bacterial virus contamination of fetal bovine sera.", "content": "Bacterial virus contamination of fetal bovine sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201071"} {"pmid": "4201083", "title": "A new taxonomic tool: serological reactions in cross-immunized baboons.", "content": "A new taxonomic tool: serological reactions in cross-immunized baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201083"} {"pmid": "4201084", "title": "Genetic markers and baboon biology.", "content": "Genetic markers and baboon biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201084"} {"pmid": "4201086", "title": "A preliminary survey of the nematode parasites of some imported Old-World monkeys.", "content": "A preliminary survey of the nematode parasites of some imported Old-World monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201086"} {"pmid": "4201087", "title": "Changes in aortic medial elastic structure at different sites in the primates Erythrocebus patas, Macaca irus and Callithrix jacchus.", "content": "Changes in aortic medial elastic structure at different sites in the primates Erythrocebus patas, Macaca irus and Callithrix jacchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201087"} {"pmid": "4201088", "title": "A restraining device for use when recording electrocardiograms in monkeys.", "content": "A restraining device for use when recording electrocardiograms in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201088"} {"pmid": "4201091", "title": "Confirmatory studies in the prenatal diagnosis of sphingolipidoses.", "content": "Confirmatory studies in the prenatal diagnosis of sphingolipidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201091"} {"pmid": "4201093", "title": "Heterologous immunity in human malaria.", "content": "Heterologous immunity in human malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201093"} {"pmid": "4201096", "title": "The microscope in the history of pathology. With a note on the pathology of fat cells.", "content": "The microscope in the history of pathology. With a note on the pathology of fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201096"} {"pmid": "4201098", "title": "Antor-pyloric gastrinoma associated with pancreatic nesidioblastosis and proliferation of islets.", "content": "Antor-pyloric gastrinoma associated with pancreatic nesidioblastosis and proliferation of islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201098"} {"pmid": "4201099", "title": "Studies on dentinogenesis in the rat. Ethane-1-hydroxy-1,1-diphosphonate (EHDP) inhibits crystal growth in predentin calcification.", "content": "Studies on dentinogenesis in the rat. Ethane-1-hydroxy-1,1-diphosphonate (EHDP) inhibits crystal growth in predentin calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201099"} {"pmid": "4201101", "title": "The use of viruses for the control of insect pests and disease vectors. Report of a joint FAO-WHO meeting on insect viruses.", "content": "The use of viruses for the control of insect pests and disease vectors. Report of a joint FAO-WHO meeting on insect viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201101"} {"pmid": "4201100", "title": "Pancreatic and hepatic ultrastructure in offspring of rabbits with protein malnutrition.", "content": "Pancreatic and hepatic ultrastructure in offspring of rabbits with protein malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201100"} {"pmid": "4201102", "title": "Estimation of immunoreactive insulin in serum, heparinized and EDTA-plasma.", "content": "Estimation of immunoreactive insulin in serum, heparinized and EDTA-plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201102"} {"pmid": "4201104", "title": "Trabeculectomy in the owl monkey.", "content": "Trabeculectomy in the owl monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201104"} {"pmid": "4201103", "title": "Protective effect of anti-mouse-skin-epithelium rabbit-IgG on survival of mouse-skin homografts.", "content": "Protective effect of anti-mouse-skin-epithelium rabbit-IgG on survival of mouse-skin homografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201103"} {"pmid": "4201105", "title": "Animal studies on the kinetics of benzidine and 3,3'-dichlorobenzidine.", "content": "Animal studies on the kinetics of benzidine and 3,3'-dichlorobenzidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201105"} {"pmid": "4201106", "title": "Enzymes of the glucuronic acid pathway in wistar and gunn rats and their heterozygotes.", "content": "Enzymes of the glucuronic acid pathway in wistar and gunn rats and their heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201106"} {"pmid": "4201107", "title": "Suppression of transcription of the ribosomal RNA cistrons of Drosophila melanogaster in a structurally rearranged chromosome.", "content": "Suppression of transcription of the ribosomal RNA cistrons of Drosophila melanogaster in a structurally rearranged chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201107"} {"pmid": "4201108", "title": "Alkaline phosphatase of Drosophila melanogaster. II. Biochemical comparison among four allelic forms.", "content": "Alkaline phosphatase of Drosophila melanogaster. II. Biochemical comparison among four allelic forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201108"} {"pmid": "4201110", "title": "A proteinase and proteinase inhibitor of mammalian sperm acrosomes.", "content": "A proteinase and proteinase inhibitor of mammalian sperm acrosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201110"} {"pmid": "4201109", "title": "Characterization of acid phosphatase-1 null activity mutants of Drosophila melanogaster.", "content": "Characterization of acid phosphatase-1 null activity mutants of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201109"} {"pmid": "4201111", "title": "Hormonal regulation of rat uterine glycogen metabolism.", "content": "Hormonal regulation of rat uterine glycogen metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201111"} {"pmid": "4201112", "title": "Soluble intracrystalline polysaccharides from coccoliths of Coccolithus huxleyi (Lohmann) Kamptner (I).", "content": "Soluble intracrystalline polysaccharides from coccoliths of Coccolithus huxleyi (Lohmann) Kamptner (I).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201112"} {"pmid": "4201113", "title": "Analysis of proliferation and differentiation of foetal granulocyte-macrophage progenitor cells in haemopoietic tissue.", "content": "Analysis of proliferation and differentiation of foetal granulocyte-macrophage progenitor cells in haemopoietic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201113"} {"pmid": "4201116", "title": "Survival of certain microorganisms subjected to rapid and very rapid freezing on membrane filters.", "content": "Survival of certain microorganisms subjected to rapid and very rapid freezing on membrane filters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201116"} {"pmid": "4201114", "title": "Circulating conversion products of C3 in liver disease. Evidence for in vivo activation of the complement system.", "content": "Circulating conversion products of C3 in liver disease. Evidence for in vivo activation of the complement system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201114"} {"pmid": "4201115", "title": "Demonstration of the production of the long acting thyroid stimulator (LATS) by peripheral lymphocytes cultured in vitro.", "content": "Demonstration of the production of the long acting thyroid stimulator (LATS) by peripheral lymphocytes cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201115"} {"pmid": "4201118", "title": "The occurrence of ribothymidine, 1-methyladenosine, methylated guanosines and the corresponding methyltransferases in E. coli and Bacillus subtilis.", "content": "The occurrence of ribothymidine, 1-methyladenosine, methylated guanosines and the corresponding methyltransferases in E. coli and Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201118"} {"pmid": "4201117", "title": "Immunological studies in the multiple hemoglobins of tadpole and frog of Rana catesbeiana.", "content": "Immunological studies in the multiple hemoglobins of tadpole and frog of Rana catesbeiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201117"} {"pmid": "4201119", "title": "Antibodies to rat brain choline acetyltransferase: species and organ specificity.", "content": "Antibodies to rat brain choline acetyltransferase: species and organ specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201119"} {"pmid": "4201120", "title": "The molecular status of the large polypeptides of erythrocyte membranes.", "content": "The molecular status of the large polypeptides of erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201120"} {"pmid": "4201121", "title": "Day care meets geriatric needs.", "content": "Day care meets geriatric needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201121"} {"pmid": "4201122", "title": "Parvoviruses.", "content": "Parvoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201122"} {"pmid": "4201124", "title": "Subacute sclerosing panencephalitis measles virus: study of biological markers.", "content": "Subacute sclerosing panencephalitis measles virus: study of biological markers. Comparative studies between two measles virus strains isolated from patients with subacute sclerosing panencephalitis (SSPE) and a prototype low tissue culture passage Edmonston measles virus are described. Differences were noted in several properties. The findings described in this report suggest that strains of measles virus associated with SSPE have different biological properties and apparently cannot be distinguished from laboratory and field strains of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201124"} {"pmid": "4201123", "title": "An R.N.", "content": "An R.N.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201123"} {"pmid": "4201145", "title": "Estimation of total body potassium in normal adolescents by whole-body counting: age and sex differences.", "content": "Estimation of total body potassium in normal adolescents by whole-body counting: age and sex differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201145"} {"pmid": "4201147", "title": "Advances in surgery.", "content": "Advances in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201147"} {"pmid": "4201146", "title": "Role of external support in the prevention of ankle sprains.", "content": "Role of external support in the prevention of ankle sprains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201146"} {"pmid": "4201148", "title": "Advances in the treatment of infectious diseases.", "content": "Advances in the treatment of infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201148"} {"pmid": "4201149", "title": "Simultaneous extraction of RNA and DNA from rat liver with cupric sulfate.", "content": "Simultaneous extraction of RNA and DNA from rat liver with cupric sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201149"} {"pmid": "4201150", "title": "Preparation of an IgM and IgA enriched fraction for clinical use.", "content": "Preparation of an IgM and IgA enriched fraction for clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201150"} {"pmid": "4201151", "title": "Adrenocortical cells in rats bearing a corticosterone secreting tumor.", "content": "Adrenocortical cells in rats bearing a corticosterone secreting tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201151"} {"pmid": "4201153", "title": "Effect of hypoxia on the fine structure of the catecholamine-storing cells of the human fetal paraganglia.", "content": "Effect of hypoxia on the fine structure of the catecholamine-storing cells of the human fetal paraganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201153"} {"pmid": "4201152", "title": "Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. Changes in the pars recta during fluorocitrate poisoning.", "content": "Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. Changes in the pars recta during fluorocitrate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201152"} {"pmid": "4201154", "title": "The use of xylitol in long-term parenteral nutrition in dogs.", "content": "The use of xylitol in long-term parenteral nutrition in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201154"} {"pmid": "4201157", "title": "Effect of polyphloretin-phosphate, an inhibitor of prostaglandins, on the spontaneous and induced motility of isolated rat uterus.", "content": "Effect of polyphloretin-phosphate, an inhibitor of prostaglandins, on the spontaneous and induced motility of isolated rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201157"} {"pmid": "4201159", "title": "The independent functions of the two heads of the lateral pterygoid muscle.", "content": "The independent functions of the two heads of the lateral pterygoid muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201159"} {"pmid": "4201158", "title": "Frostbite. A discussion of the problem and a review of an Alaskan experience.", "content": "Frostbite. A discussion of the problem and a review of an Alaskan experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201158"} {"pmid": "4201160", "title": "Ciliary activity in the human and Macaca nemestrina oviduct.", "content": "Ciliary activity in the human and Macaca nemestrina oviduct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201160"} {"pmid": "4201169", "title": "Alpha-foetoprotein: purification on sepharose-linked concanavalin-A.", "content": "Alpha-foetoprotein: purification on sepharose-linked concanavalin-A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201169"} {"pmid": "4201168", "title": "A human IgG myeloma protein crystallizing with rhombohedral symmetry.", "content": "A human IgG myeloma protein crystallizing with rhombohedral symmetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201168"} {"pmid": "4201173", "title": "Transcription specificity of an RNA polymerase fraction from bacteriophage SP01-infected B. subtilis.", "content": "Transcription specificity of an RNA polymerase fraction from bacteriophage SP01-infected B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201173"} {"pmid": "4201172", "title": "Serum beta2-microglobulin levels in normal children and sex-linked agammaglobulinemia patients.", "content": "Serum beta2-microglobulin levels in normal children and sex-linked agammaglobulinemia patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201172"} {"pmid": "4201175", "title": "Radiosensitization of bacterial spores by potassium permanganate.", "content": "Radiosensitization of bacterial spores by potassium permanganate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201175"} {"pmid": "4201174", "title": "The pancreatic beta-cell recognition of insulin secretagogues. Inhibitory effects of a membrane probe on the islet uptake and insulin-releasing action of glibenclamide.", "content": "The pancreatic beta-cell recognition of insulin secretagogues. Inhibitory effects of a membrane probe on the islet uptake and insulin-releasing action of glibenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201174"} {"pmid": "4201176", "title": "Mechanism for lysozyme-catalyzed hydrolysis.", "content": "Mechanism for lysozyme-catalyzed hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201176"} {"pmid": "4201177", "title": "Laboratory diagnosis of bovine paratuberculosis.", "content": "Laboratory diagnosis of bovine paratuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201177"} {"pmid": "4201178", "title": "Interaction of glutaraldehyde with spheroplasts of Escherichia coli.", "content": "Interaction of glutaraldehyde with spheroplasts of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201178"} {"pmid": "4201179", "title": "Gliding motility in some non-spreading flexibacteria.", "content": "Gliding motility in some non-spreading flexibacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201179"} {"pmid": "4201180", "title": "Measurement of heat resistance parameters for spores isolated from canned products.", "content": "Measurement of heat resistance parameters for spores isolated from canned products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201180"} {"pmid": "4201181", "title": "Concanavalin A increases the strength of baby hamster kidney cell attachment to substratum.", "content": "Concanavalin A increases the strength of baby hamster kidney cell attachment to substratum. The strength of attachment of normal and transformed baby hamster kidney cells was markedly increased when attached cells were treated with concanavalin A (Con A). The cells became less sensitive to detachment by physical shear or by treatment with trypsin or EDTA; however, their morphology, as observed by phase contrast microscopy, did not change. The effects of Con A were prevented by the simultaneous addition of either D-glucose or alpha-methyl-D-glucoside with the Con A. Also addition of these reagents to the attached cells after Con A treatment partially reversed the effects caused by Con A. Pre-treatment of the culture flasks with Con A before cell attachment resulted in an increase in the strength of cell attachment to the culture flasks as compared to untreated controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201181"} {"pmid": "4201182", "title": "Aporphines. 8. Total synthesis and pharmacological evaluation of (plus or minus)-apomorphine, (plus or minus)-apocodeine, (plus or minus)-N-n-propylnorapomorphine, and (plus or minus)-N-n-propylnorapocodeine.", "content": "Aporphines. 8. Total synthesis and pharmacological evaluation of (plus or minus)-apomorphine, (plus or minus)-apocodeine, (plus or minus)-N-n-propylnorapomorphine, and (plus or minus)-N-n-propylnorapocodeine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201182"} {"pmid": "4201183", "title": "Synthesis and antitumor and antibacterial activity of benzoquinones related to the mitomycins.", "content": "Synthesis and antitumor and antibacterial activity of benzoquinones related to the mitomycins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201183"} {"pmid": "4201184", "title": "Pyrrole antibacterial agents. 1. Compounds related to pyoluteorin.", "content": "Pyrrole antibacterial agents. 1. Compounds related to pyoluteorin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201184"} {"pmid": "4201185", "title": "14Alpha, 17 alpha-alkylidenedioxy steroids. 2. 19-Nor-9 alpha, 10 beta- and 19-nor-9 beta, 10 alpha-progesterone analogs.", "content": "14Alpha, 17 alpha-alkylidenedioxy steroids. 2. 19-Nor-9 alpha, 10 beta- and 19-nor-9 beta, 10 alpha-progesterone analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201185"} {"pmid": "4201186", "title": "Terminal riboadenylate transferase: a poly A polymerase in purified vaccinia virus.", "content": "Terminal riboadenylate transferase: a poly A polymerase in purified vaccinia virus. Purified vaccinia virus treated with Triton X-100 catalyzes the incorporation of ATP into an acid-insoluble product. The enzymatic activity responsible for the ATP polymerization is demonstrated to be different from vaccinia RNA polymerase in its preferential use of ATP as substrate and on the basis of heat stability, pH optima, and metal ion requirement. The ATP polymerization reaction is stimulated 10-fold by the addition of rA(pA)(5.) In accordance with our earlier terminology, we call this Mn(2+)-dependent enzyme terminal riboadenylate transferase to distinguish it from Mg(2+)-dependent poly A polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201186"} {"pmid": "4201189", "title": "Effect of nalidixic acid on PBS2 bacteriophage infection of Bacillus subtilis.", "content": "Effect of nalidixic acid on PBS2 bacteriophage infection of Bacillus subtilis. Infection of Bacillus subtilis by PBS2 phage, whose DNA contains uracil instead of thymine, is relatively unaffected by low concentrations of nalidixic acid which severely inhibit B. subtilis DNA synthesis. High concentrations of nalidixic acid do inhibit PBS2 DNA synthesis, but more severely reduce the burst size of PBS2 infections. Hydroxyurea blocks PBS2 DNA synthesis, preventing progeny phage production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201189"} {"pmid": "4201187", "title": "Specificity of formation of complexes between coat protein and bacteriophage f2 RNA.", "content": "Specificity of formation of complexes between coat protein and bacteriophage f2 RNA. The specificity of formation of phage f2 RNA-protein complexes was studied. Complex I contains up to 8 mol of coat protein per 1 mol of RNA. Its formation proceeds equally well in medium (i) without magnesium ions, (ii) containing magnesium ions, (iii) containing 4 mM EDTA, and (iv) at temperatures from 0 to 45 C. Complex II contains up to 200 mol of coat protein per 1 mol of RNA. Its formation is inhibited by the presence of magnesium ions in medium. Formaldehyde- or methoxyamine-treated f2 RNA in which only exposed bases were modified showed a normal pattern of complex II formation, whereas formation of complex I was inhibited or abolished. We conclude that complex I formation involves the interaction between coat protein and specific region of exposed bases in RNA. A possible site of attachment of coat protein is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201187"} {"pmid": "4201188", "title": "Replication of dengue virus type 2 in Aedes albopictus cell culture.", "content": "Replication of dengue virus type 2 in Aedes albopictus cell culture. The replication of type 2 dengue (D-2) virus in Aedes albopictus (Aal) mosquito cell cultures differed from that in vertebrate (LLC-MK2) rhesus monkey kidney cells. Virus readily replicated in Aal cells at either 30 or 37 C, but had no apparent effect on the host cell. Persistent infection was established with continual virus production for at least 6 months, although the virulence of progeny virus for both suckling mice and LLC-MK2 cells became attenuated. Density gradient analysis of infected Aal cell supernatant products indicated that only complete virus was released, in contrast to infected LLC-MK2 cells which also released incomplete virus. The surface antigens of the virus produced in Aal cells appeared to be considerably modified in that antiserum to vertebrate cell-produced D-2 virus did not block hemagglutination, whereas anti-Aal cell antiserum did. Virus infectivity could be neutralized by the antiserum to D-2 virus grown in vertebrate cells, however. Virus produced in LLC-MK2 cells did not demonstrate a similar host-cell modification. These results may reflect a difference in the mechanism by which D-2 virus matures in Aal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201188"} {"pmid": "4201191", "title": "Hand, foot and mouth disease: an outbreak with interesting virological features.", "content": "Hand, foot and mouth disease: an outbreak with interesting virological features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201191"} {"pmid": "4201192", "title": "An evaluation of the use of sensitized latex particles for the detection of the hepatitis-associated antigen.", "content": "An evaluation of the use of sensitized latex particles for the detection of the hepatitis-associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201192"} {"pmid": "4201195", "title": "Acute inhalation toxicology and proposed emergency exposure limits of nitrogen trifluoride.", "content": "Acute inhalation toxicology and proposed emergency exposure limits of nitrogen trifluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201195"} {"pmid": "4201196", "title": "Induced reversible pigment alteration in Stentor coeruleus.", "content": "Induced reversible pigment alteration in Stentor coeruleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201196"} {"pmid": "4201197", "title": "The role of acrocentric chromosomes in nucleolar organization. II. Constancy of the nucleolar area independent of the number of acrocentric chromosomes in meningioma cell cultures.", "content": "The role of acrocentric chromosomes in nucleolar organization. II. Constancy of the nucleolar area independent of the number of acrocentric chromosomes in meningioma cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201197"} {"pmid": "4201198", "title": "Fine structure and silver-staining patterns of lysosome-like bodies in absorptive cells of the small intestine in normal children and children with a lysosomal storage disease.", "content": "Fine structure and silver-staining patterns of lysosome-like bodies in absorptive cells of the small intestine in normal children and children with a lysosomal storage disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201198"} {"pmid": "4201199", "title": "Further studies on the ultrastructure of the pars distalis of castrated male mice pituitary.", "content": "Further studies on the ultrastructure of the pars distalis of castrated male mice pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201199"} {"pmid": "4201201", "title": "Platelets and carbon clearance rates in rabbits affected by a tubercle bacillary lipid or endotoxin.", "content": "Platelets and carbon clearance rates in rabbits affected by a tubercle bacillary lipid or endotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201201"} {"pmid": "4201202", "title": "Deletion of cells by apoptosis during castration-induced involution of the rat prostate.", "content": "Deletion of cells by apoptosis during castration-induced involution of the rat prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201202"} {"pmid": "4201203", "title": "Teratocarcinoma with the capacity for differentiation restricted to neuro-ectodermal tissue.", "content": "Teratocarcinoma with the capacity for differentiation restricted to neuro-ectodermal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201203"} {"pmid": "4201204", "title": "Degeneration and regeneration of the adrenergic nerves in the rat iris induced by dihydroxytryptamines.", "content": "Degeneration and regeneration of the adrenergic nerves in the rat iris induced by dihydroxytryptamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201204"} {"pmid": "4201206", "title": "Proliferation of epithelial cells in the jejunal crypts of adrenalectomized and adrenocortical hormone treated rats.", "content": "Proliferation of epithelial cells in the jejunal crypts of adrenalectomized and adrenocortical hormone treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201206"} {"pmid": "4201207", "title": "Effect of an a' aqueous extract of small intestinal mucosa on the G-2 phase of jejunal proliferative cells in mice.", "content": "Effect of an a' aqueous extract of small intestinal mucosa on the G-2 phase of jejunal proliferative cells in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201207"} {"pmid": "4201209", "title": "Visualization of human glomerular changes by scanning electron microscopy.", "content": "Visualization of human glomerular changes by scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201209"} {"pmid": "4201210", "title": "Effects of azide, thioglycollic acid, and nitrosoguanidine on growth and nitrogen fixation in different clones of the blue-green alga Cylindrospermum majus.", "content": "Effects of azide, thioglycollic acid, and nitrosoguanidine on growth and nitrogen fixation in different clones of the blue-green alga Cylindrospermum majus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201210"} {"pmid": "4201211", "title": "Descent of cerevrospinal fluid to spinal subarachnoid space.", "content": "Descent of cerevrospinal fluid to spinal subarachnoid space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201211"} {"pmid": "4201212", "title": "Lactose feeding and lactase deficiency.", "content": "Lactose feeding and lactase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201212"} {"pmid": "4201213", "title": "Microbial contamination of the gut: another feature of malnutrition.", "content": "Microbial contamination of the gut: another feature of malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201213"} {"pmid": "4201215", "title": "Serum vitamin A in protein-calorie malnutrition.", "content": "Serum vitamin A in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201215"} {"pmid": "4201214", "title": "Plasma amino acid curve in rats force-fed a single meal lacking an essential amino acod.", "content": "Plasma amino acid curve in rats force-fed a single meal lacking an essential amino acod.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201214"} {"pmid": "4201216", "title": "Lactose feeding in lactose-intolerant monkeys.", "content": "Lactose feeding in lactose-intolerant monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201216"} {"pmid": "4201217", "title": "Lens depression and aqueous outflow in enucleated primate eyes.", "content": "Lens depression and aqueous outflow in enucleated primate eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201217"} {"pmid": "4201218", "title": "Ascending and descending optic atrophy produced experimentally in squirrel monkeys.", "content": "Ascending and descending optic atrophy produced experimentally in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201218"} {"pmid": "4201219", "title": "Cloverleaf skull syndrome.", "content": "Cloverleaf skull syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201219"} {"pmid": "4201220", "title": "Norrie's disease (hereditary oculo-acoustic-cerebral degeneration). Report of a United States family.", "content": "Norrie's disease (hereditary oculo-acoustic-cerebral degeneration). Report of a United States family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201220"} {"pmid": "4201221", "title": "Epiphrenic diverticula. An analysis of 80 cases.", "content": "Epiphrenic diverticula. An analysis of 80 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201221"} {"pmid": "4201222", "title": "Immune response of the bovine fetus to several antigens.", "content": "Immune response of the bovine fetus to several antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201222"} {"pmid": "4201223", "title": "Thiosulfate and survival of Leptospira autumnalis Akiyami A.", "content": "Thiosulfate and survival of Leptospira autumnalis Akiyami A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201223"} {"pmid": "4201224", "title": "Thyroid abnormalities in renal failure. A study of 53 patients on chronic hemodialysis.", "content": "Thyroid abnormalities in renal failure. A study of 53 patients on chronic hemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201224"} {"pmid": "4201225", "title": "Pseudomonas aeruginosa vaccine in cancer patients.", "content": "Pseudomonas aeruginosa vaccine in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201225"} {"pmid": "4201226", "title": "Immunocompetence of patients with protein-calorie malnutrition. The effects of nutritional repletion.", "content": "Immunocompetence of patients with protein-calorie malnutrition. The effects of nutritional repletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201226"} {"pmid": "4201227", "title": "Pathogenesis of \"transplant lung\". I. Interstitial pulmonary edema.", "content": "Pathogenesis of \"transplant lung\". I. Interstitial pulmonary edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201227"} {"pmid": "4201229", "title": "Red-cell fluid and electrolytes during hemorrhagic shock in the monkey.", "content": "Red-cell fluid and electrolytes during hemorrhagic shock in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201229"} {"pmid": "4201228", "title": "Pseudomyxoma peritonaei: a report of ten cases.", "content": "Pseudomyxoma peritonaei: a report of ten cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201228"} {"pmid": "4201230", "title": "Chlorpromazine treatment of disturbed monkeys.", "content": "Chlorpromazine treatment of disturbed monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201230"} {"pmid": "4201231", "title": "The phenogenetics of a super-suppressor in Drosophila melanogaster. 3. Suppression at individual loci.", "content": "The phenogenetics of a super-suppressor in Drosophila melanogaster. 3. Suppression at individual loci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201231"} {"pmid": "4201232", "title": "The melanocyte system of cattle skin. II. Melanotic melanocytes of epidermis and dermis.", "content": "The melanocyte system of cattle skin. II. Melanotic melanocytes of epidermis and dermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201232"} {"pmid": "4201233", "title": "A survey of the genitalia of bulls in Northern Australia.", "content": "A survey of the genitalia of bulls in Northern Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201233"} {"pmid": "4201234", "title": "Differences in eukaryotic ribosomes detected by the selective action of an antibiotic.", "content": "Differences in eukaryotic ribosomes detected by the selective action of an antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201234"} {"pmid": "4201235", "title": "Effect of the administration of L-azetidine-2-carboxylic acid on albumin and transferrin biosynthesis by liver slices of rats treated with carbon tetrachloride.", "content": "Effect of the administration of L-azetidine-2-carboxylic acid on albumin and transferrin biosynthesis by liver slices of rats treated with carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201235"} {"pmid": "4201236", "title": "Studies on the biological properties of coelomic fluid of sea urchin. I. Naturally occurring hemolysin in sea urchin.", "content": "Studies on the biological properties of coelomic fluid of sea urchin. I. Naturally occurring hemolysin in sea urchin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201236"} {"pmid": "4201237", "title": "Differences in the content of chondroitin sulfate C and chondroitin sulfate A in the epiphysial growth cartilages of human vertebrae and long bones.", "content": "Differences in the content of chondroitin sulfate C and chondroitin sulfate A in the epiphysial growth cartilages of human vertebrae and long bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201237"} {"pmid": "4201238", "title": "Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.", "content": "Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201238"} {"pmid": "4201239", "title": "Coordination of heme and globin synthesis in primate reticulocytes.", "content": "Coordination of heme and globin synthesis in primate reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201239"} {"pmid": "4201240", "title": "Letter: 23Na interaction with bacterial surfaces: a comment on nuclear magnetic resonance invisible signals.", "content": "Letter: 23Na interaction with bacterial surfaces: a comment on nuclear magnetic resonance invisible signals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201240"} {"pmid": "4201241", "title": "Serological tests for syphilis in pregnancy. False and missed positive reactions.", "content": "Serological tests for syphilis in pregnancy. False and missed positive reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201241"} {"pmid": "4201242", "title": "Survival of Neisseria gonorrhoeae in an artificial subcutaneous cavity of the mouse.", "content": "Survival of Neisseria gonorrhoeae in an artificial subcutaneous cavity of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201242"} {"pmid": "4201243", "title": "Growth and effect of Neisseria gonorrhoeae in organ cultures.", "content": "Growth and effect of Neisseria gonorrhoeae in organ cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201243"} {"pmid": "4201244", "title": "Transgrow (Clinicult) in the laboratory diagnosis of gonorrhoea.", "content": "Transgrow (Clinicult) in the laboratory diagnosis of gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201244"} {"pmid": "4201246", "title": "Incidence of gonorrhoea in Denmark, 1957-1971.", "content": "Incidence of gonorrhoea in Denmark, 1957-1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201246"} {"pmid": "4201245", "title": "Vancomycin-sensitive strains of Neisseria gonorrhoeae. A problem for the diagnostic laboratory.", "content": "Vancomycin-sensitive strains of Neisseria gonorrhoeae. A problem for the diagnostic laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201245"} {"pmid": "4201247", "title": "Collagenolytic activities of squamous cell carcinoma of the skin.", "content": "Collagenolytic activities of squamous cell carcinoma of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201247"} {"pmid": "4201248", "title": "Microsomal metabolism of dimethylnitrosamine and the cytochrome P-450 dependency of its activation to a mutagen.", "content": "Microsomal metabolism of dimethylnitrosamine and the cytochrome P-450 dependency of its activation to a mutagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201248"} {"pmid": "4201249", "title": "The effect of haemodialysis on the binding capacity of albumin.", "content": "The effect of haemodialysis on the binding capacity of albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201249"} {"pmid": "4201250", "title": "The use of polymerized antisera for the determination of human placental alkaline phosphatase in pregnancy sera.", "content": "The use of polymerized antisera for the determination of human placental alkaline phosphatase in pregnancy sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201250"} {"pmid": "4201252", "title": "A sensitive radioimmunoassay for thyrotropin releasing hormone.", "content": "A sensitive radioimmunoassay for thyrotropin releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201252"} {"pmid": "4201253", "title": "Factors in blood influencing the determination of thyrotropin releasing hormone.", "content": "Factors in blood influencing the determination of thyrotropin releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201253"} {"pmid": "4201254", "title": "Evaluation of a specific protein analyser.", "content": "Evaluation of a specific protein analyser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201254"} {"pmid": "4201255", "title": "Work simplification of a competitive protein binding analysis for serum thyroxine. A study of some analytical variables affecting accuracy and precision.", "content": "Work simplification of a competitive protein binding analysis for serum thyroxine. A study of some analytical variables affecting accuracy and precision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201255"} {"pmid": "4201256", "title": "Plasma thyrotropin levels in severe infantile malnutrition.", "content": "Plasma thyrotropin levels in severe infantile malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201256"} {"pmid": "4201257", "title": "Prolactin production by monkey (Macaca mulatta) anterior pituitaries cultured in vitro.", "content": "Prolactin production by monkey (Macaca mulatta) anterior pituitaries cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201257"} {"pmid": "4201258", "title": "Loss of immunoreactivity of human serum parathyroid hormone by the action of rat kidney enzyme, preferentially hydrolyzing parathyroid hormone.", "content": "Loss of immunoreactivity of human serum parathyroid hormone by the action of rat kidney enzyme, preferentially hydrolyzing parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201258"} {"pmid": "4201260", "title": "Effect of EDTA on utilization of dietary zinc by G-F swine.", "content": "Effect of EDTA on utilization of dietary zinc by G-F swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201260"} {"pmid": "4201259", "title": "Pony cecum vs. steer rumen: the effect of oats and hay on the microbial ecosystem.", "content": "Pony cecum vs. steer rumen: the effect of oats and hay on the microbial ecosystem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201259"} {"pmid": "4201261", "title": "Mathematical model of a head subjected to an angular acceleration.", "content": "Mathematical model of a head subjected to an angular acceleration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201261"} {"pmid": "4201262", "title": "Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIII.", "content": "Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIII. The antibiotic ristocetin, in concentrations of 1.0-1.5 mg/ml, aggregated normal platelets in citrated platelet-rich plasma by a mechanism in which the release reaction played only a minor role. Platelet aggregation by ristocetin in a concentration of 1.2 mg/ml was absent or markedly decreased in 10 patients with von Willebrand's disease. Lesser degrees of abnormality were obtained with a concentration of 1.5 mg/ml. The magnitude of the defect in ristocetin-induced platelet aggregation correlated well with the degree of abnormality of the bleeding time and the levels of antihemophilic factor (AHF, VIII(AHF)) procoagulant activity. In all patients, the defect in ristocetin-induced platelet aggregation was corrected in vitro by normal plasma. Correction was also obtained with a fraction of normal cryoprecipitate that eluted in the void volume with VIII(AHF) after chromatography on a gel that excludes molecules larger than 5 x 10(6). A similar fraction, devoid of VIII(AHF) activity, obtained from patients with von Willebrand's disease had no corrective effect, but fractions obtained from patients with hemophilia were just as effective as those obtained from normal subjects. The correction activity of plasma and partially purified factor VIII was inhibited by a rabbit antibody to human factor VIII but not by a human antibody against VIII(AHF) procoagulant activity. The studies provide further evidence that patients with von Willebrand's disease are deficient in a plasma factor that is necessary for normal platelet function. The activity of this factor appears to be associated with factor VIII but is unrelated to VIII(AHF) procoagulant activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201262"} {"pmid": "4201263", "title": "Evidence that the ciliary inhibitor of cystic fibrosis is not an antibody.", "content": "Evidence that the ciliary inhibitor of cystic fibrosis is not an antibody. An inhibitor of ciliary activity is present in the serum of cystic fibrosis (CF) patients and heterozygotes. Fractionation of CF serum has indicated that the inhibitor is associated with the serum IgG fraction. This study compared the activity of the CF inhibitor to that of rabbit antibody preparations directed against oyster cilia. The aim of this investigation was to determine whether the ciliary inhibitory mechanism in cystic fibrosis is related to a typical immunological reaction. Results from experiments utilizing fluorescent antibody techniques demonstrated that an antiserum directed against oyster ciliated epithelium binds immunologically with both human bronchial and oyster epithelial tissue. Results from experiments utilizing immunofluorescent tracing, passive hemagglutination, double immunodiffusion, and papain digestion, however, indicated that the interaction between the oyster cilia and the CF serum inhibitor was not a typical antigen-antibody reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201263"} {"pmid": "4201264", "title": "Antihemophilic factor antigen. Localization in endothelial cells by immunofluorescent microscopy.", "content": "Antihemophilic factor antigen. Localization in endothelial cells by immunofluorescent microscopy. The tissue localization of antihemophilic factor (AHF, Factor VIII) has been determined by immunofluorescent studies using monospecific rabbit antibody to human AHF. Specific staining demonstrating AHF antigens has been identified in endothelial cells of a wide range of human tissues. The staining pattern was observed in endothelial cells of arteries, capillaries, and veins as well as the cells lining hepatic and splenic sinusoids. Specific fluorescence was limited to these endothelial cells in sections of kidney, liver, spleen, lymph node, cardiac and smooth muscle, thyroid, umbilical cord, and skin. Absorption studies established that the staining was specific for cells in which there were proteins that had AHF antigens. The demonstration of fluorescence within the cytoplasm of endothelial cells suggests that these cells synthesize proteins that have AHF antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201264"} {"pmid": "4201266", "title": "Interrelationships between the human alveolar macrophage and alpha-1-antitrypsin.", "content": "Interrelationships between the human alveolar macrophage and alpha-1-antitrypsin. Alveolar macrophages lavaged from human lungs contain protease activity at an optimum pH of 3.0 and possibly a lesser peak of activity at pH 5.5. Protease activity measured at pH 4.1 is inhibited by purified alpha-1-antitrypsin. Fluorescent antibody studies of human alveolar macrophages showed that alpha-1-antitrypsin is present in normal alveolar macrophages. In addition, macrophages from a patient with a homozygous deficiency of alpha-1-antitrypsin exhibited less fluorescence when incubated in autologous serum than the same macrophages incubated in normal serum. Macrophages from normal subjects showed maximal fluorescence when removed from the lung and additional incubation with serum did not increase fluorescence. These results implicate the human alveolar macrophage as a possible source of an enzyme that may cause emphysema in patients deficient in alpha-1-antitrypsin. They also show that alpha-1-antitrypsin has access to the alveolus in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201266"} {"pmid": "4201265", "title": "Suppression of pituitary TSH secretion in the patient with a hyperfunctioning thyroid nodule.", "content": "Suppression of pituitary TSH secretion in the patient with a hyperfunctioning thyroid nodule. 10 patients with a single hyperfunctioning thyroid nodule each were studied for pituitary thyrotropin (TSH) suppression. They were judged to be euthyroid on clinical grounds. The total thyroxine (T(4)D), free thyroxine (FT(4)), total triiodothyronine (T(3)D), and free triiodothyronine (FT(3)) were normal in most of the patients. Incorporation of (131)I into the hyperfunctioning thyroid nodules was not suppressed by the administration of physiological doses of T(3). Basal serum TSH concentrations were undetectable (<0.5 - 1.0 muU/ml) in all patients. The metabolic clearance of TSH in one patient before and after excision of the thyroid nodule was unchanged (40 vs. 42 ml/min) whereas the calculated production rate was undetectable before the operation (<29 mU/day) and normal after (103 mU/day). These data, in one patient, suggest that the undetectable concentration of TSH in these patients is a result of suppressed TSH secretion rather than accelerated TSH clearance. In eight patients, basal serum TSH concentrations failed to increase after the intravenous administration of 200 mug of thyrotropin-releasing hormone (TRH); minimal increases in serum TSH concentrations were observed in two patients. The suppression of TSH was evident despite \"normal\" concentrations of circulating thyroid hormones. The observation that normal serum concentrations of T(4)D, FT(4), T(3)D, and FT(3) may be associated with undetectable basal serum TSH concentrations and suppressed TSH response to TRH was also found in four hypothyroid patients given increasing doses of L-thyroxine and sequential TRH stimulation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201265"} {"pmid": "4201269", "title": "Inhibition of vasopressin-stimulated urea transport across the toad bladder by thiourea.", "content": "Inhibition of vasopressin-stimulated urea transport across the toad bladder by thiourea. The mammalian antidiuretic hormone, 8-arginine-vasopressin, was found to increase net mucosal-to-serosal urea flux across the isolated toad urinary bladder 13-fold. This urea flux was accompanied by a 24-fold increase in solute-linked water movement across the membrane. Net urea flux and urea-linked volume flux were inhibited by 50% or more when thiourea was added to the mucosal medium at concentrations equal to those of urea. In contrast, thiourea did not inhibit osmotic water flux across the bladder in the presence of vasopressin. These observations are consistant with the view that thiourea and urea compete for a common site on a membrane carrier molecule. When bladders were exposed to vasopressin on the serosa and subsequently fixed with 1% glutaraldehyde on the mucosa, they were found to retain 74% of their prefixation permeability to urea. Net urea flux across these fixed bladders (in the absence of vasopressin) was markedly inhibited by thiourea, whereas osmotic water flux was not inhibited. These studies suggest that vasopressin induces the formation of \"urea-channels\" in the membrane that can be preserved by glutaraldehyde and blocked by thiourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201269"} {"pmid": "4201267", "title": "The effects of nitroglycerin on coronary collaterals and myocardial contractility.", "content": "The effects of nitroglycerin on coronary collaterals and myocardial contractility. Nitroglycerin (TNG) causes a prolonged dilatation of coronary collaterals. To demonstrate a functional significance of this dilatation we measured the effect of TNG on myocardial contractile force in dogs 2(1/2)-4 wk after the left anterior descending coronary artery (LAD) had been embolized in closed-chest animals. Development of collaterals was documented by angiography. Via a left thoracotomy the main left coronary artery (LCA) and LAD distal to the embolized plug were cannulated. Coronary flow and perfusion pressure were recorded. Contractile force was measured with gauges sutured to epicardial areas supplied by the left circumflex coronary artery (LCf) and occluded LAD. Coronary perfusion pressure in the LCA was gradually decreased until the contractile force recorded by the LAD gauge diminished while the LCf gauge was unaffected. Under these conditions, with coronary perfusion pressure held constant with the aid of a Starling resistance, TNG (18 mug) injected into the LCA increased peripheral LAD pressure by 3-12 mm Hg and contractile force in the LAD region by 36% (range 20-90%), returning it to near-normal levels, while having minimal effect in the LCf area. These changes persisted for 5 min. When LCf and LAD areas were both ischemic, intracoronary TNG had minimal effect on peripheral LAD pressure and contractile force. Thus, TNG causes prolonged dilatation of coronary collaterals and presumed increased collateral flow with subsequent enhancement of myocardial contractile force in ischemic areas. This effect is seen only when ischemia is limited to an area supplied by the collaterals. When the whole heart is ischemic, collaterals are unresponsive to TNG, suggesting that these collaterals dilate fully when the regions from which they originate become ischemic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201267"} {"pmid": "4201270", "title": "Radioimmunoassay of thyrotrophin releasing hormone.", "content": "Radioimmunoassay of thyrotrophin releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201270"} {"pmid": "4201271", "title": "Subcellular distribution and some properties of the enzyme activity involved in the breakdown of tritiated lysine vasopressin by bovine neurohypophyses.", "content": "Subcellular distribution and some properties of the enzyme activity involved in the breakdown of tritiated lysine vasopressin by bovine neurohypophyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201271"} {"pmid": "4201268", "title": "Quantitative determination of antibody to gonococcal pili. Changes in antibody levels with gonococcal infection.", "content": "Quantitative determination of antibody to gonococcal pili. Changes in antibody levels with gonococcal infection. Gonococcal pili, pure by the criteria of electron microscopic examination and polyacrylamide gel electrophoresis in sodium dodecyl sulfate, have been prepared by repeated cycles of precipitation with 0.1 M MgCl(2), followed by dissolution in 0.01 M Tris pH 8, 0.01 M NaN(3). Using a fluorescein-conjugated antibody prepared to pili from a single strain, pilar antigen(s) was found to be present in each of 18 strains of gonococci tested, and absent from strains of pilated meningococci, nonpathogenic Neisseria sp., and Escherichia coli. Purified pili, labeled with (125)I were used in an antigen binding assay to quantitatively measure antibody to pili in rabbit sera and in 561 human sera. The range of antibody activity for 133 persons unlikely to have experienced gonorrhea was 0.1-1.6 mug/ml with a geometric mean of 0.5 mug/ml. This geometric mean antibody activity was significantly lower than the geometric mean for asymptomatically infected males (1.0 mug/ml, P < 0.002), males with symptomatic gonococcal anterior urethritis (1.6 mug/ml, P < 0.001), or asymptomatically infected females (4.2 mug/ml, P < 0.001). Antibody appeared in elevated levels (> 1.6 mug/ml) 2-3 wk after infection and returned toward control levels 1 or more months after treatment. Antibody levels higher than 1.6 mug/ml were found in 26 (50%) of 52 males with gonococcal anterior urethritis, in 10 (33%) of 30 males with asymptomatic urethral infection and in 50 (89%) of 56 asymptomatically infected females. In a high-risk group of 103 females for whom culture results and antibody to pili were compared, 58 (57%) had elevated antibody levels to pili and 86% of the infected females were within this seropositive group. The antigen binding assay may provide a means to detect asymptomatic gonococcal infection in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201268"} {"pmid": "4201273", "title": "Glyceryl trinitrate and pentrinitrol (pentaerythritol trinitrate): comparative cardiovascular effects in dog, cat and rat by different routes of administration.", "content": "Glyceryl trinitrate and pentrinitrol (pentaerythritol trinitrate): comparative cardiovascular effects in dog, cat and rat by different routes of administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201273"} {"pmid": "4201272", "title": "The designation of the major guinea-pig neural lobe protein as a neurophysin.", "content": "The designation of the major guinea-pig neural lobe protein as a neurophysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201272"} {"pmid": "4201274", "title": "Effect of the prostaglandin synthesis inhibitors indomethacin and eicosa-5,8,11,14-tetraynoic acid on adrenergic responses in dog cutaneous vasculature.", "content": "Effect of the prostaglandin synthesis inhibitors indomethacin and eicosa-5,8,11,14-tetraynoic acid on adrenergic responses in dog cutaneous vasculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201274"} {"pmid": "4201276", "title": "Metabolism of 3H-estrone sulfate perfused in vivo through a rhesus monkey liver.", "content": "Metabolism of 3H-estrone sulfate perfused in vivo through a rhesus monkey liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201276"} {"pmid": "4201275", "title": "Sulfhydryl requirement for relaxation of vascular smooth muscle.", "content": "Sulfhydryl requirement for relaxation of vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201275"} {"pmid": "4201278", "title": "The effect of glyceryl trinitrate (nitroglycerin on the coronary hemodynamics in man.", "content": "The effect of glyceryl trinitrate (nitroglycerin on the coronary hemodynamics in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201278"} {"pmid": "4201285", "title": "Morphological and autoradiographical investigations on experimental carcinogenesis and polyp development in the intestinal tract of rats and mice.", "content": "Morphological and autoradiographical investigations on experimental carcinogenesis and polyp development in the intestinal tract of rats and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201285"} {"pmid": "4201291", "title": "Radioimmunological evidence for early functional activity in chick embryonic beta cells.", "content": "Radioimmunological evidence for early functional activity in chick embryonic beta cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201291"} {"pmid": "4201292", "title": "Timely topics in microbiology 1971: gram negative bacteria.", "content": "Timely topics in microbiology 1971: gram negative bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201292"} {"pmid": "4201293", "title": "A microneutralization test for canine distemper virus.", "content": "A microneutralization test for canine distemper virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201293"} {"pmid": "4201294", "title": "Vaccination of calves and milking cows with different strains of Theileria annulata.", "content": "Vaccination of calves and milking cows with different strains of Theileria annulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201294"} {"pmid": "4201295", "title": "Propranolol and LB 46 (prinodolol) in angina pectoris. A comparative long-term ergometric study.", "content": "Propranolol and LB 46 (prinodolol) in angina pectoris. A comparative long-term ergometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201295"} {"pmid": "4201296", "title": "Linkage data on Rh, PGM1, PGD, Peptidase C and Fy from family studies.", "content": "Linkage data on Rh, PGM1, PGD, Peptidase C and Fy from family studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201296"} {"pmid": "4201297", "title": "The blood groups of Icelanders.", "content": "The blood groups of Icelanders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201297"} {"pmid": "4201299", "title": "Evaluation of an indirect fluorescent antibody test for detecting Babesia argentina infection in cattle.", "content": "Evaluation of an indirect fluorescent antibody test for detecting Babesia argentina infection in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201299"} {"pmid": "4201300", "title": "A cowpox-like infection in man caused by Coxsackie A type 16 virus.", "content": "A cowpox-like infection in man caused by Coxsackie A type 16 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201300"} {"pmid": "4201301", "title": "A rapid method for the purification of glycogen synthetase I and D utilising concanavalin A bound to agarose.", "content": "A rapid method for the purification of glycogen synthetase I and D utilising concanavalin A bound to agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201301"} {"pmid": "4201302", "title": "Galactosyl (alpha 1--4)galactosylceramide: galactosyl hydrolase activity in normal and Fabry plasma.", "content": "Galactosyl (alpha 1--4)galactosylceramide: galactosyl hydrolase activity in normal and Fabry plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201302"} {"pmid": "4201303", "title": "Pronase digestion of amino-acid binding components on the surface of Bacillus subtilis cells and minicells.", "content": "Pronase digestion of amino-acid binding components on the surface of Bacillus subtilis cells and minicells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201303"} {"pmid": "4201305", "title": "A comparison of the unfolding and dissociation of the large ribosome subunits from Rhodopseudomonas spheroides N.C.I.B. 8253 and Escherichia coli M.R.E. 600.", "content": "A comparison of the unfolding and dissociation of the large ribosome subunits from Rhodopseudomonas spheroides N.C.I.B. 8253 and Escherichia coli M.R.E. 600. 1. The behaviour of the large ribosomal subunit from Rhodopseudomonas spheroides (45S) has been compared with the 50S ribosome from Escherichia coli M.R.E. 600 (and E. coli M.R.E. 162) during unfolding by removal of Mg(2+) and detachment of ribosomal proteins by high univalent cation concentrations. The extent to which these processes are reversible with these ribosomes has also been examined. 2. The R. spheroides 45S ribosome unfolds relatively slowly but then gives rise directly to two ribonucleoprotein particles (16.6S and 13.7S); the former contains the intact primary structure of the 16.25S rRNA species and the latter the 15.00S rRNA species of the original ribosome. No detectable protein loss occurs during unfolding. The E. coli ribosome unfolds via a series of discrete intermediates to a single, unfolded ribonucleoprotein unit (19.1S) containing the 23S rRNA and all the protein of the original ribosome. 3. The two unfolded R. spheroides ribonucleoproteins did not recombine when the original conditions were restored but each simply assumed a more compact configuration. Similar treatments reversed the unfolding of the E. coli 50S ribosomes; replacement of Mg(2+) caused the refolding of the initial products of unfolding and in the presence of Ni(2+) the completely unfolded species (19.1S) again sedimented at the same rate as the original ribosomes (44S). 4. Ribosomal proteins (25%) were dissociated from R. spheroides 45S ribosomes by dialysis against a solution with a Na(+)/Mg(2+) ratio of 250:1. During this process two core particles were formed (21.2S and 14.2S) and the primary structures of the two original rRNA species were conserved. This dissociation was not reversed. With E. coli 50S approximately 15% of the original ribosomal protein was dissociated, a single 37.6S core particle was formed, the 23S rRNA remained intact and the ribosomal proteins would reassociate with the core particle to give a 50S ribosome. 5. The ribonuclease activities in R. spheroides 45S and E. coli M.R.E. 600 and E. coli M.R.E. 162 50S ribosomes are compared. 6. The observations concerning unfolding and dissociation are consistent with previous reports showing the unusual rRNA complement of the mature R. spheroides 45S ribosome and show the dependence of these events upon the rRNA and the importance of protein-protein interactions in the structure of the R. spheroides ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201305"} {"pmid": "4201304", "title": "The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism.", "content": "The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. 1. alpha(2)-Macroglobulin is known to bind and inhibit a number of serine proteinases. We show that it binds thiol and carboxyl proteinases, and there is now reason to believe that alpha(2)-macroglobulin can bind essentially all proteinases. 2. Radiochemically labelled trypsin, chymotrypsin, cathepsin B1 and papain are bound by alpha(2)-macroglobulin in an approximately equimolar ratio. Equimolar binding was confirmed for trypsin by activesite titration. 3. Pretreatment of alpha(2)-macroglobulin with a saturating amount of one proteinase prevented the subsequent binding of another. We conclude that each molecule of alpha(2)-macroglobulin is able to react with one molecule of proteinase only. 4. alpha(2)-Macroglobulin did not react with exopeptidases, non-proteolytic hydrolases or inactive forms of endopeptidases. 5. The literature on binding and inhibition of proteinases by alpha(2)-macroglobulin is reviewed, and from consideration of this and our own work several general characteristics of the interaction can be discerned. 6. A model is proposed for the molecular mechanism of the interaction of alpha(2)-macroglobulin with proteinases. It is suggested that the enzyme cleaves a peptide bond in a sensitive region of the macroglobulin, and that this results in a conformational change in the alpha(2)-macroglobulin molecule that traps the enzyme irreversibly. Access of substrates to the active site of the enzyme becomes sterically hindered, causing inhibition that is most pronounced with large substrate molecules. 7. The possible physiological importance of the unique binding characteristics of alpha(2)-macroglobulin is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201304"} {"pmid": "4201306", "title": "Cholesterol ester hydrolysis in aortic tissue.", "content": "Cholesterol ester hydrolysis in aortic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201306"} {"pmid": "4201307", "title": "The effects of frontal cortical ablations on alcohol selection and emotionality in pigtail monkeys (Macaca nemistrina).", "content": "The effects of frontal cortical ablations on alcohol selection and emotionality in pigtail monkeys (Macaca nemistrina).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201307"} {"pmid": "4201308", "title": "Toxicology and pharmacology of the nitrosoureas.", "content": "Toxicology and pharmacology of the nitrosoureas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201308"} {"pmid": "4201309", "title": "Formulation of three nitrosoureas for intravenous use.", "content": "Formulation of three nitrosoureas for intravenous use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201309"} {"pmid": "4201310", "title": "Response of vaccinated swine to group E streptococcus exposure.", "content": "Response of vaccinated swine to group E streptococcus exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201310"} {"pmid": "4201311", "title": "Swine abscesses caused by Lancefield's group E streptococci. XI. Application of the hemagglutination test to demonstrate a correlation between the antigens of group E and streptococcus uberis, and their relation to antibodies induced by unknown organisms.", "content": "Swine abscesses caused by Lancefield's group E streptococci. XI. Application of the hemagglutination test to demonstrate a correlation between the antigens of group E and streptococcus uberis, and their relation to antibodies induced by unknown organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201311"} {"pmid": "4201312", "title": "Bromazepam and phenobarbital in anxiety: a controlled study.", "content": "Bromazepam and phenobarbital in anxiety: a controlled study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201312"} {"pmid": "4201313", "title": "A double-blind, comparative clinical trial with ludiomil (CIBA 34,276-Ba) and amitriptyline in newly admitted depressed patients.", "content": "A double-blind, comparative clinical trial with ludiomil (CIBA 34,276-Ba) and amitriptyline in newly admitted depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201313"} {"pmid": "4201314", "title": "A controlled study of single-dose administration of imipramine pamoate in endogenous depression.", "content": "A controlled study of single-dose administration of imipramine pamoate in endogenous depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201314"} {"pmid": "4201315", "title": "Experiences on a sustained-release procainamide preparation.", "content": "Experiences on a sustained-release procainamide preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201315"} {"pmid": "4201317", "title": "Clinical and laboratory evaluation of cefazolin: a new cephalosporin antibiotic in pediatric patients.", "content": "Clinical and laboratory evaluation of cefazolin: a new cephalosporin antibiotic in pediatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201317"} {"pmid": "4201316", "title": "Diuretic effect of butoxymethylen furosemide (FFBU) in healthy subjects: a preliminary study.", "content": "Diuretic effect of butoxymethylen furosemide (FFBU) in healthy subjects: a preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201316"} {"pmid": "4201320", "title": "Conservation of intestinal bile acid concentration after ileal resection.", "content": "Conservation of intestinal bile acid concentration after ileal resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201320"} {"pmid": "4201321", "title": "Serological reactions of glycolipids from streptococcal L-forms.", "content": "Serological reactions of glycolipids from streptococcal L-forms. Parent bacteria and L-forms of some streptococci of group A, group D, and Streptococcus MG share common antigens as shown by cross-reactivity in growth inhibition, complement fixation, and Ouchterlony tests. Cross-reactivity between these streptococci or their L-forms with a staphylococcal L-form, or Mycoplasma pneumoniae, was found only rarely and only in low-titer complement fixation tests. Removal of all three serological reactivities from positive antisera by addition of chloroform-methanol (7:3) extracts of the streptococci or their L-forms, and failure to remove activities by protein extracts, indicated the glycolipid nature of the cross-reacting antigenic determinants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201321"} {"pmid": "4201323", "title": "Isolation of a new simian foamy virus from a spider monkey brain culture.", "content": "Isolation of a new simian foamy virus from a spider monkey brain culture. A syncytium-forming (foamy) virus was isolated from a spider monkey brain cell culture. Cytopathic effect was observed both in the brain culture and in human embryonic kidney cells. Neutralizing antibody was present in the sera of the spider monkey from whom the isolation was made. The virus was inhibited by 5-bromo-2-deoxyuridine (20 mug/ml), contained a ribonucleic acid-dependent deoxyribonucleic acid polymerase, and had an infectivity peak at 1.15 g/cm(3) in a sucrose density gradient. The virus passed through a 220-nm but not a 100-nm membrane filter, was chloroform sensitive, and was inactivated at 56 C in 30 min. Hemagglutinating and hemadsorption activity was not noted with a variety of erythrocytes. The virion was spherical, formed in the cytoplasm, and was 105 to 115 nm in diameter. Ring-shaped nucleoids, 45 to 50 nm in diameter, were associated with tubular profiles. The virus was not neutralized by sera prepared against known viruses, including simian foamy virus types 1 through 7, Mason-Pfizer monkey virus, and bovine syncytial and measles viruses. Sera from a rabbit hyperimmunized with the isolate and sera from 19 spider monkeys had neutralizing antibody to the isolate; however, these sera did not cross-react with simian foamy virus types 1 through 7. Neutralizing antibody to the isolate was not detected in sera from 16 humans, 9 rhesus monkeys, and 10 chimpanzees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201323"} {"pmid": "4201322", "title": "Purification and characterization of thermostable direct hemolysin of Vibrio parahaemolyticus.", "content": "Purification and characterization of thermostable direct hemolysin of Vibrio parahaemolyticus. A thermostable direct hemolysin was purified from culture filtrates of Vibrio parahaemolyticus. The purified hemolysin gave one precipitation line with the antihemolysin antiserum on agar-gel diffusion test and a single band on polyacrylamide gel electrophoresis. The hemolysin was not inactivated by heating at 70 to 100 C for 10 min. The hemolytic activity was not enhanced by the addition of lecithin. It was demonstrated that the hemolysin was a protein with a molecular weight of approximately 118,000. Amino acid analysis revealed that 43% of total amino acids were acidic amino acids, whereas 11% were basic amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201322"} {"pmid": "4201324", "title": "Platelet enhancement of postphagocytic destruction of Listeria monocytogenes in cultured mouse peritoneal macrophages.", "content": "Platelet enhancement of postphagocytic destruction of Listeria monocytogenes in cultured mouse peritoneal macrophages. Rabbit platelets enhance the bactericidal capability of cultured mouse peritoneal macrophages against Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201324"} {"pmid": "4201326", "title": "Determination of mean cell size of Tetrahymena in growing cultures.", "content": "Determination of mean cell size of Tetrahymena in growing cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201326"} {"pmid": "4201325", "title": "Production of exo-beta-N-acetylglucosaminidase by Bacillus subtilis B.", "content": "Production of exo-beta-N-acetylglucosaminidase by Bacillus subtilis B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201325"} {"pmid": "4201327", "title": "The neutral and alkaline proteases of Aspergillus nidulans.", "content": "The neutral and alkaline proteases of Aspergillus nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201327"} {"pmid": "4201328", "title": "Effect of autologous bone marrow transplantation and an anabolic steroid on erythropoietin production and hemopoietic recovery after whole body irradiation and treatment with alkylating agents.", "content": "Effect of autologous bone marrow transplantation and an anabolic steroid on erythropoietin production and hemopoietic recovery after whole body irradiation and treatment with alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201328"} {"pmid": "4201347", "title": "Possible therapy in hereditary angioneurotic edema (HAE).", "content": "Possible therapy in hereditary angioneurotic edema (HAE).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201347"} {"pmid": "4201349", "title": "Cytological analysis of storage effects on various types of complete and mosaic change induced in drosophila chromosomes by some chemical mutagens.", "content": "Cytological analysis of storage effects on various types of complete and mosaic change induced in drosophila chromosomes by some chemical mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201349"} {"pmid": "4201351", "title": "Recovery of the subhuman primate after deep cerebral hypothermia and prolonged ischaemia.", "content": "Recovery of the subhuman primate after deep cerebral hypothermia and prolonged ischaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201351"} {"pmid": "4201352", "title": "Selective inactivation of the D or I forms of glycogen synthetase from rat skeletal muscle.", "content": "Selective inactivation of the D or I forms of glycogen synthetase from rat skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201352"} {"pmid": "4201355", "title": "Germination of actinomycete spores.", "content": "Germination of actinomycete spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201355"} {"pmid": "4201356", "title": "Fibrinogen catabolism in Plasmodium knowlesi malaria.", "content": "Fibrinogen catabolism in Plasmodium knowlesi malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201356"} {"pmid": "4201357", "title": "Survey of microsporidan hyperparasites of trematode larvae from Malaysian snails.", "content": "Survey of microsporidan hyperparasites of trematode larvae from Malaysian snails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201357"} {"pmid": "4201358", "title": "Microdissection of scrub typhus vectors.", "content": "Microdissection of scrub typhus vectors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201358"} {"pmid": "4201360", "title": "Microsporidian infection in Lymnaea rubiginosa.", "content": "Microsporidian infection in Lymnaea rubiginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201360"} {"pmid": "4201359", "title": "Plaque formation in vero cell cultures by some Malaysian viruses.", "content": "Plaque formation in vero cell cultures by some Malaysian viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201359"} {"pmid": "4201361", "title": "An orang asli blowpipe with a syringe-type dart for the liver capture of wild parimates in Malaysia.", "content": "An orang asli blowpipe with a syringe-type dart for the liver capture of wild parimates in Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201361"} {"pmid": "4201362", "title": "Simian neonatology. II. Neonatal pathology.", "content": "Simian neonatology. II. Neonatal pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201362"} {"pmid": "4201363", "title": "Simian neonatology. 3. The causes of neonatal mortality.", "content": "Simian neonatology. 3. The causes of neonatal mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201363"} {"pmid": "4201364", "title": "Mast cells and postnatal topographic anomalies in mammalian subfornical body and supraoptic crest.", "content": "Mast cells and postnatal topographic anomalies in mammalian subfornical body and supraoptic crest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201364"} {"pmid": "4201367", "title": "Bacterial pollution and disinfection of the colonofiberscope. II. Ethylene oxide gas sterilization.", "content": "Bacterial pollution and disinfection of the colonofiberscope. II. Ethylene oxide gas sterilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201367"} {"pmid": "4201366", "title": "Protein-calorie malnutrition and intellect in childhood: A review.", "content": "Protein-calorie malnutrition and intellect in childhood: A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201366"} {"pmid": "4201368", "title": "Hepatitis B. A study of 200 cases positive for the hepatitis B antigen.", "content": "Hepatitis B. A study of 200 cases positive for the hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201368"} {"pmid": "4201369", "title": "Bacterial pollution and disinfection of the colonofiberscope. I. An investigation of traditional sterilization methods.", "content": "Bacterial pollution and disinfection of the colonofiberscope. I. An investigation of traditional sterilization methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201369"} {"pmid": "4201371", "title": "Intramural diverticulosis of the esophagus.", "content": "Intramural diverticulosis of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201371"} {"pmid": "4201370", "title": "Epsilon-aminocaproic acid therapy in ulcerative colitis.", "content": "Epsilon-aminocaproic acid therapy in ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201370"} {"pmid": "4201372", "title": "Effects of certain purified plasma proteins on the compatibility of glass with blood.", "content": "Effects of certain purified plasma proteins on the compatibility of glass with blood. The effects of certain purified plasma proteins on the coagulation-activation and platelet-adhesion properties of glass surfaces have been investigated. Albumin, transferrin, gammaG globulin, gammaM globulin and fibrinogen were obtained in highly purified form; ceruloplasmin was a more crude preparation. Each of these proteins was found to adhere to glass surfaces and influence reactions of these surfaces with blood. gammaG globulin or albumin adsorbed to glass markedly inhibited activation of the intrinsic coagulation system, while the other proteins tested were much less effective in this respect. Fibrinogen, of all the proteins tested, greatly enhanced the adhesion of platelets to glass. Albumin, ceruloplasmin, transferrin, gammaG globulin and gammaM globulin each decreased the adhesion of platelets to glass by approximately 50%. Ultrastructural studies of the interface area where blood reacted with the layer of protein adsorbed to glass demonstrated the deposition of a moderately thick irregular protein layer upon the surface, with adhesion of cellular elements to this unilaminar adsorbed layer. Ultrastructural studies also demonstrated that platelets which adhere to protein-coated surfaces formed pseudopods and spread upon such surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201372"} {"pmid": "4201374", "title": "Hereditary angio-neurotic oedema. Genealogical and immunological studies.", "content": "Hereditary angio-neurotic oedema. Genealogical and immunological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201374"} {"pmid": "4201373", "title": "Cultured skin fibroblasts in storage disorders. An analysis of ultrastructural features.", "content": "Cultured skin fibroblasts in storage disorders. An analysis of ultrastructural features. Electron microscopic studies were performed on cultured fibroblasts from patients with metachromatic leukodystrophy, Fabry's, Gaucher's, Niemann-Pick's (Type A and C), Sanfilippo's (Type A and B) disease, chondroitin-4-sulfate mucopolysaccharidosis, lipofuscinosis (Spielmeyer-Vogt's disease) and ceroid-lipofuscinosis (Batten's disease with curvilinear bodies). Specific cytoplasmic inclusions with a limiting membrane were identified in Fabry's disease, Niemann-Pick syndrome, chondroitin-4-sulfate mucopolysaccharidosis and Sanfilippo's Type B disease. In Fabry's disease, the lipid inclusions tended to form stacks of parallel and concentric membranes. In Niemann-Pick syndrome, the lipid inclusions were made of wavy, loosely packed membranes. In chondroitin-4-sulfate mucopolysaccharidosis and Sanfilippo B, the lysosomes were enlarged and contained a reticular matrix with little electron-dense material. No specific ultrastructural changes were observed in Gaucher's, Sanfilippo's (Type A) disease, metachromatic leukodystrophy (sulfatidosis) and Batten's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201373"} {"pmid": "4201377", "title": "The nature and biological activity of IPN virus neutralizing antibodies in normal and immunized rainbow trout (Salmo gairdneri).", "content": "The nature and biological activity of IPN virus neutralizing antibodies in normal and immunized rainbow trout (Salmo gairdneri).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201377"} {"pmid": "4201376", "title": "Presence of neutralizing antibody to canine distemper virus in sera of patients with subacute sclerosing panencephalitis.", "content": "Presence of neutralizing antibody to canine distemper virus in sera of patients with subacute sclerosing panencephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201376"} {"pmid": "4201379", "title": "Determination of polychlorinated biphenyl (Aroclor 1242) migration into food types.", "content": "Determination of polychlorinated biphenyl (Aroclor 1242) migration into food types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201379"} {"pmid": "4201380", "title": "Polychlorinated terphenyls in the environment.", "content": "Polychlorinated terphenyls in the environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201380"} {"pmid": "4201382", "title": "Oral toxicity of chlorinated dibenzofurans to juvenile Atlantic salmon.", "content": "Oral toxicity of chlorinated dibenzofurans to juvenile Atlantic salmon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201382"} {"pmid": "4201381", "title": "Inhibition of aflatoxin and zearalenone biosynthesis with dichlorvos.", "content": "Inhibition of aflatoxin and zearalenone biosynthesis with dichlorvos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201381"} {"pmid": "4201383", "title": "Oxidation of polychlorinated biphenyls by achromobacter pCB.", "content": "Oxidation of polychlorinated biphenyls by achromobacter pCB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201383"} {"pmid": "4201384", "title": "Determination of polychlorinated biphenyl (PCB's) residues in grades of pulp, paper and paperboard.", "content": "Determination of polychlorinated biphenyl (PCB's) residues in grades of pulp, paper and paperboard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201384"} {"pmid": "4201386", "title": "The occurrence of polychlorinated biphenyls (PCB's) in silage stored in pit and upright silos.", "content": "The occurrence of polychlorinated biphenyls (PCB's) in silage stored in pit and upright silos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201386"} {"pmid": "4201385", "title": "Electron-capturing compounds and selected elements in paper.", "content": "Electron-capturing compounds and selected elements in paper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201385"} {"pmid": "4201387", "title": "Whole body skeletal scintiphotography in the detection of occult metastatic breast carcinomas.", "content": "Whole body skeletal scintiphotography in the detection of occult metastatic breast carcinomas. Whole body skeletal scintiphotography was carried out in a series of 111 breast cancer patients. The results of scintiphotography were compared with the results of roentgenography and with the diagnostic usefulness of serum alkaline phosphatase levels and the presence or absence of bone pain. In 27 percent of cases, lesions were first identified with the scintiphotos. When lesions were present on both scintiphotos and roentgenograms, involvement generally appeared greater on the scintiphotos. Two false negative studies were recorded. Sixty-seven percent of patients with early metastasis-that is, those with positive scintiphotos and negative roentgenograms-were asymptomatic. Serum alkaline phosphatase levels were normal in 38 percent of those with early skeletal involvement. Skeletal scintiphotography is superior to other commonly employed techniques used to assess bone metastasis in breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201387"} {"pmid": "4201388", "title": "Atypical diabetic coma.", "content": "Atypical diabetic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201388"} {"pmid": "4201399", "title": "IgG-1(kappa) M component after bone marrow transplantation.", "content": "IgG-1(kappa) M component after bone marrow transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201399"} {"pmid": "4201400", "title": "Biosynthesis of the fifth component of complement (C5) by human fetal tissues.", "content": "Biosynthesis of the fifth component of complement (C5) by human fetal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201400"} {"pmid": "4201401", "title": "Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids.", "content": "Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201401"} {"pmid": "4201402", "title": "Generation of chemotactic factors in guinea pig serum via activation of the classical and alternate complement pathways.", "content": "Generation of chemotactic factors in guinea pig serum via activation of the classical and alternate complement pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201402"} {"pmid": "4201403", "title": "Thirty-two fatal cases of severe diabetic ketoacidosis, including a case of mucormycosis.", "content": "Thirty-two fatal cases of severe diabetic ketoacidosis, including a case of mucormycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201403"} {"pmid": "4201409", "title": "Experimental allergic uveitis. Studies on characterization and isolation of the pathogenic retina antigen.", "content": "Experimental allergic uveitis. Studies on characterization and isolation of the pathogenic retina antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201409"} {"pmid": "4201410", "title": "Serological studies of Haemophilus influenzae. IV. The antibody response in rabbits against capsular and O antigens of H. influenzae.", "content": "Serological studies of Haemophilus influenzae. IV. The antibody response in rabbits against capsular and O antigens of H. influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201410"} {"pmid": "4201412", "title": "Leucocyte migration inhibition to Mycoplasma fermentans in patients with rheumatoid arthritis.", "content": "Leucocyte migration inhibition to Mycoplasma fermentans in patients with rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201412"} {"pmid": "4201411", "title": "Tubular lesions produced by autoantibodies to tubular basement membrane in human renal allografts.", "content": "Tubular lesions produced by autoantibodies to tubular basement membrane in human renal allografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201411"} {"pmid": "4201414", "title": "The effect of hypoxia on radiation life-shortening in Drosophila melanogaster.", "content": "The effect of hypoxia on radiation life-shortening in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201414"} {"pmid": "4201413", "title": "Inhibition of allergic reactions by cromoglycate and by AH 7079 in patients with allergic airway disease.", "content": "Inhibition of allergic reactions by cromoglycate and by AH 7079 in patients with allergic airway disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201413"} {"pmid": "4201415", "title": "The location of antibacterial activity in the rat prostatic secretions.", "content": "The location of antibacterial activity in the rat prostatic secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201415"} {"pmid": "4201416", "title": "Inhibition of bacterial urease.", "content": "Inhibition of bacterial urease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201416"} {"pmid": "4201417", "title": "Prolactin and growth hormone release in response to sequential stimulation by arginine and synthetic TRF.", "content": "Prolactin and growth hormone release in response to sequential stimulation by arginine and synthetic TRF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201417"} {"pmid": "4201418", "title": "Alpha chain of glycoprotein hormones: presence in human serum after thyroid stimulating hormone releasing hormone.", "content": "Alpha chain of glycoprotein hormones: presence in human serum after thyroid stimulating hormone releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201418"} {"pmid": "4201419", "title": "Ultrastructure of giant pigment granules (macromelanosomes) in the cutaneous pigmented macules of neurofibromatosis.", "content": "Ultrastructure of giant pigment granules (macromelanosomes) in the cutaneous pigmented macules of neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201419"} {"pmid": "4201420", "title": "Oxidation of furans. 2. Synthesis and biological properties of 6-hydroxy-2H-pyran-3(6H)-ones and derivatives.", "content": "Oxidation of furans. 2. Synthesis and biological properties of 6-hydroxy-2H-pyran-3(6H)-ones and derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201420"} {"pmid": "4201421", "title": "In vivo metabolite condensations. Formation of N1-ethyl-2-methyl-N3-(2,6-dimethylphenyl)-4-imidazolidinone from the reaction of a metabolite of alcohol with a metabolite of lidocaine.", "content": "In vivo metabolite condensations. Formation of N1-ethyl-2-methyl-N3-(2,6-dimethylphenyl)-4-imidazolidinone from the reaction of a metabolite of alcohol with a metabolite of lidocaine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201421"} {"pmid": "4201422", "title": "Synthesis of the thyrotropin-releasing hormone enantiomer and some diastereoisomers and in vitro studies of their biological activity.", "content": "Synthesis of the thyrotropin-releasing hormone enantiomer and some diastereoisomers and in vitro studies of their biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201422"} {"pmid": "4201407", "title": "Tubeless hypotónic duodenography.", "content": "Tubeless hypotónic duodenography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201407"} {"pmid": "4201423", "title": "Synthesis of antimicrobial nitroimidazolyl 2-sulfides, -sulfoxides, and -sulfones.", "content": "Synthesis of antimicrobial nitroimidazolyl 2-sulfides, -sulfoxides, and -sulfones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201423"} {"pmid": "4201408", "title": "Protective role of prednisolone upon galactosamine-induced hepatitis in rats.", "content": "Protective role of prednisolone upon galactosamine-induced hepatitis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201408"} {"pmid": "4201424", "title": "Methotrexate analogs. 2. A facile method of preparation of lipophilic derivatives of methotrexate and 3',5'-dichloromethotrexate by direct esterification.", "content": "Methotrexate analogs. 2. A facile method of preparation of lipophilic derivatives of methotrexate and 3',5'-dichloromethotrexate by direct esterification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201424"} {"pmid": "4201425", "title": "Cordycepin and alpha-amanitin: inhibitors of transcription as probes of aldosterone action.", "content": "Cordycepin and alpha-amanitin: inhibitors of transcription as probes of aldosterone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201425"} {"pmid": "4201426", "title": "Prevention and mitigation of head injury from antiquity to the present.", "content": "Prevention and mitigation of head injury from antiquity to the present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201426"} {"pmid": "4201427", "title": "The mechanism of injury in blunt abdominal trauma.", "content": "The mechanism of injury in blunt abdominal trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201427"} {"pmid": "4201428", "title": "Defective hemoglobin function: a complication of hyperalimentation.", "content": "Defective hemoglobin function: a complication of hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201428"} {"pmid": "4201429", "title": "Lung transplantation: a review of its current studies.", "content": "Lung transplantation: a review of its current studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201429"} {"pmid": "4201430", "title": "Response to thyrotropin-releasing hormone compared with thyroid suppression tests in euthyroid Graves' disease.", "content": "Response to thyrotropin-releasing hormone compared with thyroid suppression tests in euthyroid Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201430"} {"pmid": "4201431", "title": "Evolution of 5S RNA and the non-randomness of base replacement.", "content": "Evolution of 5S RNA and the non-randomness of base replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201431"} {"pmid": "4201433", "title": "Studies on the division cycle of mammalian cells. VII. X-ray sensitivity and repair capacity of synchronously dividing murine mastocytoma cells.", "content": "Studies on the division cycle of mammalian cells. VII. X-ray sensitivity and repair capacity of synchronously dividing murine mastocytoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201433"} {"pmid": "4201432", "title": "Alpha-fetoprotein in Rh-immunized pregnancies.", "content": "Alpha-fetoprotein in Rh-immunized pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201432"} {"pmid": "4201434", "title": "X-ray-induced alterations in marker replication pattern in Bacillus subtilis W23.", "content": "X-ray-induced alterations in marker replication pattern in Bacillus subtilis W23.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201434"} {"pmid": "4201435", "title": "Sudanophilic lipids in the unmyelinated primate cerebral white matter after intrauterine hypoxia and acidosis.", "content": "Sudanophilic lipids in the unmyelinated primate cerebral white matter after intrauterine hypoxia and acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201435"} {"pmid": "4201436", "title": "The role of ontogeny in the establishment of species-specific patterns.", "content": "The role of ontogeny in the establishment of species-specific patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201436"} {"pmid": "4201440", "title": "Laser flash photolysis studies of chlorin and porphyrin systems. I. Energetics of the triplet state of bacteriochlorophyll.", "content": "Laser flash photolysis studies of chlorin and porphyrin systems. I. Energetics of the triplet state of bacteriochlorophyll.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201440"} {"pmid": "4201442", "title": "Proceedings: Treatment of perennial childhood asthma.", "content": "Proceedings: Treatment of perennial childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201442"} {"pmid": "4201441", "title": "Effects of measles on the immune response of Nigerian children.", "content": "Effects of measles on the immune response of Nigerian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201441"} {"pmid": "4201443", "title": "Proceedings: Control of infection in children with leukaemia and lymphomas.", "content": "Proceedings: Control of infection in children with leukaemia and lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201443"} {"pmid": "4201444", "title": "Treatment of chronic urinary tract infection in children. I. Propicillin-dicloxacillin combination for Pseudomonas aeruginosa infections.", "content": "Treatment of chronic urinary tract infection in children. I. Propicillin-dicloxacillin combination for Pseudomonas aeruginosa infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201444"} {"pmid": "4201446", "title": "Letter: Monkeys for research.", "content": "Letter: Monkeys for research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201446"} {"pmid": "4201439", "title": "Fetal cell counting as a guide to prevention of Rh sensitization.", "content": "Fetal cell counting as a guide to prevention of Rh sensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201439"} {"pmid": "4201445", "title": "Phosphorylase and glycogen synthetase during myoblast differentiation.", "content": "Phosphorylase and glycogen synthetase during myoblast differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201445"} {"pmid": "4201447", "title": "Structural studies on the specific capsular polysaccharide from Rhizobium trifolii, TA-1.", "content": "Structural studies on the specific capsular polysaccharide from Rhizobium trifolii, TA-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201447"} {"pmid": "4201448", "title": "The preparation and biological activity of novel amino acid analogs of butirosin.", "content": "The preparation and biological activity of novel amino acid analogs of butirosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201448"} {"pmid": "4201449", "title": "Granulomatous bacterial arthritis.", "content": "Granulomatous bacterial arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201449"} {"pmid": "4201450", "title": "The open fracture. Cause, effect and management.", "content": "The open fracture. Cause, effect and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201450"} {"pmid": "4201438", "title": "Delay in the onset of immune hemolysis in vivo apparently due to heparinization.", "content": "Delay in the onset of immune hemolysis in vivo apparently due to heparinization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201438"} {"pmid": "4201451", "title": "Antibiotics. An overview.", "content": "Antibiotics. An overview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201451"} {"pmid": "4201452", "title": "Comparison of gram-negative bacillary and staphylococcal osteomyelitis of the femur and tibia.", "content": "Comparison of gram-negative bacillary and staphylococcal osteomyelitis of the femur and tibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201452"} {"pmid": "4201455", "title": "A comparison of the fluorometric and microbiological assays for estimating riboflavin content of blood and liver.", "content": "A comparison of the fluorometric and microbiological assays for estimating riboflavin content of blood and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201455"} {"pmid": "4201454", "title": "Australia antigen in professional blood donors and student volunteers at Poona.", "content": "Australia antigen in professional blood donors and student volunteers at Poona.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201454"} {"pmid": "4201456", "title": "Acute severe insulin resistance. A case report.", "content": "Acute severe insulin resistance. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201456"} {"pmid": "4201461", "title": "A theoretical EHT study of structure-activity relationships in a series of sulfonamides.", "content": "A theoretical EHT study of structure-activity relationships in a series of sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201461"} {"pmid": "4201466", "title": "Eye diseases in two families of animals.", "content": "Eye diseases in two families of animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201466"} {"pmid": "4201467", "title": "Undernutrition.", "content": "Undernutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201467"} {"pmid": "4201468", "title": "Nutrition and behavior and learning.", "content": "Nutrition and behavior and learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201468"} {"pmid": "4201469", "title": "Nutrition and disease.", "content": "Nutrition and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201469"} {"pmid": "4201472", "title": "Two different patterns of segmentation in eggs of Bufo arenarum.", "content": "Two different patterns of segmentation in eggs of Bufo arenarum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201472"} {"pmid": "4201470", "title": "Degradation of progesterone by aspergilli-side chain cleaving enzymes.", "content": "Degradation of progesterone by aspergilli-side chain cleaving enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201470"} {"pmid": "4201464", "title": "Blood group mosaicism involving the rhesus and Duffy blood groups.", "content": "Blood group mosaicism involving the rhesus and Duffy blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201464"} {"pmid": "4201473", "title": "Radiation induced pericarditis in Hodgkin's disease.", "content": "Radiation induced pericarditis in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201473"} {"pmid": "4201465", "title": "Three examples of Rh-positive, good responders to blood group antigens.", "content": "Three examples of Rh-positive, good responders to blood group antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201465"} {"pmid": "4201474", "title": "Behaviour of intravenously injected 51CrCl3 in irradiated and nonirradiated mice.", "content": "Behaviour of intravenously injected 51CrCl3 in irradiated and nonirradiated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201474"} {"pmid": "4201475", "title": "Electron irradiation of monkey skin.", "content": "Electron irradiation of monkey skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201475"} {"pmid": "4201476", "title": "Distribution of 226Ra in the bones of mice.", "content": "Distribution of 226Ra in the bones of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201476"} {"pmid": "4201477", "title": "Gold in the dermis following gold therapy for rheumatoid arthritis.", "content": "Gold in the dermis following gold therapy for rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201477"} {"pmid": "4201463", "title": "Identification and clinical implications of isoantibodies in patients with idiopathic dysgammaglobulinemia.", "content": "Identification and clinical implications of isoantibodies in patients with idiopathic dysgammaglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201463"} {"pmid": "4201479", "title": "Heparin sensitivity. Report of a case.", "content": "Heparin sensitivity. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201479"} {"pmid": "4201478", "title": "Diagnosis of deep infection with Candida. A study of Candida precipitins.", "content": "Diagnosis of deep infection with Candida. A study of Candida precipitins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201478"} {"pmid": "4201482", "title": "Dispersal activities of the sibling species Drosophila melanogaster and Drosophila simulans.", "content": "Dispersal activities of the sibling species Drosophila melanogaster and Drosophila simulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201482"} {"pmid": "4201483", "title": "The chemical composition and serological reactions of lipopolysaccharides from serogroups A,B,X, and Y Neisseria meningitidis.", "content": "The chemical composition and serological reactions of lipopolysaccharides from serogroups A,B,X, and Y Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201483"} {"pmid": "4201485", "title": "Hepatitis B antigen: distribution of ad and ay subtypes in blood donors and hepatitis patients.", "content": "Hepatitis B antigen: distribution of ad and ay subtypes in blood donors and hepatitis patients. Hepatitis B antigen (HBAg) from blood donors and patients with hepatitis was tested for ad and ay subspecificity by immunodiffusion in agarose. A total of 59 sera from blood donors and 81 sera from hepatitis patients were subtyped.Subtyping of HBAg from blood donors showed ad and ay subspecificity in 64.4 and 35.6% of cases respectively. Patients' sera on the other hand showed HBAg with ad and ay subspecificity in 6 and 94% of cases respectively. Therefore, ad subtype was more frequently associated with blood donors whereas ay subtype was predominant among hepatitis patients. The relationship between clinical findings and HBAg subtype is also discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201485"} {"pmid": "4201487", "title": "Editorial: In pursuit of Pneumocystis carinii.", "content": "Editorial: In pursuit of Pneumocystis carinii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201487"} {"pmid": "4201489", "title": "The extensor assembly of Saimiri sciurea.", "content": "The extensor assembly of Saimiri sciurea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201489"} {"pmid": "4201490", "title": "A logic to long-term care.", "content": "A logic to long-term care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201490"} {"pmid": "4201491", "title": "Community care for the elderly: an alternative to institutionalization.", "content": "Community care for the elderly: an alternative to institutionalization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201491"} {"pmid": "4201492", "title": "Genetical study of Angami Nagas (Nagaland, India): A1A2BO, MN, Rh blood groups, ABO(H) secretion, PTC taste sensitivity and colour-blindness.", "content": "Genetical study of Angami Nagas (Nagaland, India): A1A2BO, MN, Rh blood groups, ABO(H) secretion, PTC taste sensitivity and colour-blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201492"} {"pmid": "4201493", "title": "Further studies on genetically mediated differences in monooxygenase activities and spin state of cytochrome P450 iron from rabbit, rat, and mouse liver.", "content": "Further studies on genetically mediated differences in monooxygenase activities and spin state of cytochrome P450 iron from rabbit, rat, and mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201493"} {"pmid": "4201494", "title": "Further genetic and enzymological characterization of the three Bacillus subtilis deoxyribonucleic acid polymerases.", "content": "Further genetic and enzymological characterization of the three Bacillus subtilis deoxyribonucleic acid polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201494"} {"pmid": "4201495", "title": "Calorimetric studies of thymidylate synthesis.", "content": "Calorimetric studies of thymidylate synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201495"} {"pmid": "4201496", "title": "Polymorphism of Rhesus monkey serum prealbumin. Purification and partial structure.", "content": "Polymorphism of Rhesus monkey serum prealbumin. Purification and partial structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201496"} {"pmid": "4201497", "title": "The effects of modification of the COOH-terminal regions of bovine thyrotropin and its subunits.", "content": "The effects of modification of the COOH-terminal regions of bovine thyrotropin and its subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201497"} {"pmid": "4201498", "title": "The effects on rabbits of immunization with bovine thyroid-stimulating hormone and its subunits.", "content": "The effects on rabbits of immunization with bovine thyroid-stimulating hormone and its subunits. Rabbits were immunized with bovine thyroid-stimulating hormone (bTSH), bovine Inteinizing hormone (bLH), and their subunits. In two immunization experiments, thyroid-stimulating activity was found in the serum of 6 out of 12 rabbits immunized with bTSHbeta subunits. The thyroid-stimulating activity in the anti-bTSHbeta sera was greater at 2 h than at 8, was eluted with the globulin fraction from Sephadex G-100, was completely neutralized by both anti-bTSH and anti-rabbit gamma globulin, and was completely suppressed by administration of triiodothyronine (T(3)) to the immunized rabbit. These findings led to the conclusion that the thyroid-stimulating activity resided in soluble complexes of rabbit TSH bound to anti-bTSHbeta. Two of nine rabbits immunized with bTSH developed thyroid-stimulating activity in their serum, but it was nonsuppressible by T(3). None of the animals immunized with bTSHalpha, bLH, bLHbeta, or bLHalpha developed serum thyroid-stimulating activity.Hypopituitary hypothyroidism, evidenced by decreased serum thyroxine (T(4)) and thyroidal (131)I uptake and by the histologic appearance of large follicles with flat cells, was found in the bTSHbeta- and bTSH-immunized animals, despite the presence of thyroid-stimulating activity in the serum of many. The reasons for this paradox are unclear; possibly the complexes block the effect of TSH on the rabbit thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201498"} {"pmid": "4201499", "title": "B lymphocytes in untreated patients with malignant lymphoma and Hodgkin's disease.", "content": "B lymphocytes in untreated patients with malignant lymphoma and Hodgkin's disease. B and T lymphocytes in 37 untreated patients with malignant lymphoma and Hodgkin's disease were studied. B cells in the peripheral blood were investigated with respect to surface immunoglobulins and in a few patients with respect to intracytoplasmic immunoglobulins by means of immunofluorescence. T cell function was studied by direct phytohemagglutinin (PHA) microtest (from the same sample of whole blood), mixed lymphocyte culture (MLC), and by delayed hypersensitivity to various antigens. In the 13 patients with Hodgkin's disease the histologic subtype was nodular sclerosis in nine, lymphocyte predominant in two, mixed cellularity in two. Only one of these patients had disseminated disease (stage IV); he showed impaired cellular immunity, a very low percentage of B cells and low levels of serum immunoglobulins. Of the remaining patients with Hodgkin's disease, with one exception, normal percentages but rather low absolute numbers of B lymphocytes per mm(3) of blood were found. One patient with a low percent and low absolute number of B lymphocytes showed very high serum IgG. Of 24 patients with non-Hodgkin's malignant lymphoma, seven (29%) showed monoclonal B cell proliferation in the peripheral blood (five mukappa, two gammakappa). By morphologic criteria, 14 patients had involvement of bone marrow, five of these had involvement of peripheral blood. Four of the latter five patients showed marked increases in percentages and absolute numbers of B lymphocytes in the peripheral blood reflecting the monoclonal proliferation. In three additional patients monoclonal proliferation of lymphocytes was found by immunofluorescence although the blood smears appeared morphologically normal. Serum immunoglobulin abnormalities without monoclonal B cell proliferation in the peripheral blood were observed in six patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201499"} {"pmid": "4201500", "title": "Characterization of ileal vitamin B12 Binding using homogeneous human and hog intrinsic factors.", "content": "Characterization of ileal vitamin B12 Binding using homogeneous human and hog intrinsic factors. Elucidation of the mechanism of intrinsic factor (IF)-mediated vitamin B(12) (B(12)) binding to ileal binding sites has been hampered by the use of crude or only partially purified preparations of IF in previous studies. We have used homogeneous human IF and hog IF isolated by affinity chromatography to study [(57)Co]B(12) binding to ileal mucosal homogenates. The following observations were made: (a) Human IF-B(12) and hog IF-B(12) were bound to human, monkey, hog, dog, rabbit, mouse, hamster, and guinea pig ileal, but not jejunal, homogenates in amounts significantly greater than free B(12) or B(12) bound to five other homogeneous B(12)-binding proteins; (b) only IF-mediated B(12) binding was localized to ileal homogenates and was inhibited by EDTA; (c) values for the association constant (K(a)) for the various ileal homogenates mentioned above and human IF-B(12) and hog IF-B(12) ranged from 0.3 x 10(9) M(-1) to 13.0 x 10(9) M(-1). Apparent differences in the K(a) for human IF-B(12) and hog IF-B(12) existed in most species; (d) the number of ileal IF-B(12) binding sites per gram (wet weight) of ileal mucosa ranged from 0.3 x 10(12) to 4.9 x 10(12). The same value was always obtained with human IF-B(12) and hog IF-B(12) for any given homogenate preparation; (c) 100-fold excesses of free B(12) or human IF and hog IF devoid of B(12) did not significantly inhibit human IF-B(12) and hog IF-B(12) binding to human and hog ileal homogenates. THESE EXPERIMENTS PERFORMED WITH HOMOGENEOUS IF INDICATE THAT: (a) gastric factors other than IF are not required for B(12) binding to ileal IF-B(12)-binding sites: (b) the mechanism of ileal IF-B(12) binding is different from that of free B(12) or of B(12) bound to non-IF-B(12)-binding proteins; (c) human IF and hog IF have different structures; (d) human IF-B(12) and hog IF-B(12) bind to the same ileal binding sites; and (c) human and hog ileal IF-B(12) binding sites bind free B(12) and human and hog IF devoid of B(12) poorly, if at all.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201500"} {"pmid": "4201502", "title": "Medical education and medical care. Problems at the interface. Urban problems: Social Security and the teaching hospital.", "content": "Medical education and medical care. Problems at the interface. Urban problems: Social Security and the teaching hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201502"} {"pmid": "4201503", "title": "Medical education and medical care in Puerto Rico.", "content": "Medical education and medical care in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201503"} {"pmid": "4201501", "title": "Detection of fibrinogen antigens with two latex techniques applied to urine concentrates.", "content": "Detection of fibrinogen antigens with two latex techniques applied to urine concentrates. Fibrinogen antigens were measured either with an agglutination inhibition method (using latex particles coated with fibrinogen; Diagen test) or with a direct agglutination technique (using latex particles coated with a mixture of anti-D and anti-E antibodies; Thrombo-Wellcotest). Both methods were compared with the tanned red cell haemagglutination inhibition immunoassay (TRCHII) during progressive degradation of fibrinogen with plasmin and using purified fibrinogen fragments or urine concentrates from chronic glomerulonephritis or transplanted patients. Due to the different sensitivity of the two latex techniques to fibrinogen and its plasmin derivatives, their combined use may be helpful to distinguish the nature of the fibrinogen-like material excreted in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201501"} {"pmid": "4201504", "title": "The localization of calcium in skeletal muscle: its distribution in muscles in which the caffeine-induced contracture was arrested.", "content": "The localization of calcium in skeletal muscle: its distribution in muscles in which the caffeine-induced contracture was arrested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201504"} {"pmid": "4201505", "title": "Relapsing form of subacute necrotizing encephalomyelopathy.", "content": "Relapsing form of subacute necrotizing encephalomyelopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201505"} {"pmid": "4201508", "title": "Direct evidence for a colchicine-induced impairment in the mobility of membrane components.", "content": "Direct evidence for a colchicine-induced impairment in the mobility of membrane components. Freeze-etch electron microscopy was used to show that colchicine interacts with membranes of the ciliate protozoan Tetrahymena pyriformis. Colchicine impairs the temperature-induced translational and vertical mobility of the membrane-intercalating particles of the freeze-fractured alveolar membranes lying just below the plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201508"} {"pmid": "4201507", "title": "Intestinal resorption of gold salts used for treatment of rheumatoid arthritis.", "content": "Intestinal resorption of gold salts used for treatment of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201507"} {"pmid": "4201511", "title": "Determination of carbonic anhydrase (E.C. 4.2.1.1.) activity by means of the pH-stat-technique.", "content": "Determination of carbonic anhydrase (E.C. 4.2.1.1.) activity by means of the pH-stat-technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201511"} {"pmid": "4201513", "title": "Immunological investigations into the causes of aspecific ABR-reactions.", "content": "Immunological investigations into the causes of aspecific ABR-reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201513"} {"pmid": "4201514", "title": "Human meningoencephalitis caused by the free-living amoebae.", "content": "Human meningoencephalitis caused by the free-living amoebae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201514"} {"pmid": "4201515", "title": "Mouth care.", "content": "Mouth care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201515"} {"pmid": "4201516", "title": "Under the cover of his charm.", "content": "Under the cover of his charm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201516"} {"pmid": "4201517", "title": "A nurse for all reasons.", "content": "A nurse for all reasons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201517"} {"pmid": "4201518", "title": "Aegyptopithecus endocasts: oldest record of a pongid brain.", "content": "Aegyptopithecus endocasts: oldest record of a pongid brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201518"} {"pmid": "4201519", "title": "Semi-natural and enclosed groups of Macaca mulatta: a behavioral comparison.", "content": "Semi-natural and enclosed groups of Macaca mulatta: a behavioral comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201519"} {"pmid": "4201520", "title": "Small analytical BD-cellulose columns for rapid chromatography of aminoacyl-tRNAs.", "content": "Small analytical BD-cellulose columns for rapid chromatography of aminoacyl-tRNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201520"} {"pmid": "4201521", "title": "A rapid electrophoretic procedure for the detection of SDS-released oncorna-viral RNA using polyacrylamide-agarose gels.", "content": "A rapid electrophoretic procedure for the detection of SDS-released oncorna-viral RNA using polyacrylamide-agarose gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201521"} {"pmid": "4201524", "title": "Isozyme variability in species of the genus Drosophila. VII. Genotype-environment relationships in populations of D. melanogaster from the Eastern United States.", "content": "Isozyme variability in species of the genus Drosophila. VII. Genotype-environment relationships in populations of D. melanogaster from the Eastern United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201524"} {"pmid": "4201523", "title": "Glucose 6-phosphate dehydrogenase from brook, lake, and splake trout: an isozymic and immunological study.", "content": "Glucose 6-phosphate dehydrogenase from brook, lake, and splake trout: an isozymic and immunological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201523"} {"pmid": "4201526", "title": "Regulation of phenylalanine biosynthesis in Pseudomonas aeruginosa.", "content": "Regulation of phenylalanine biosynthesis in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201526"} {"pmid": "4201525", "title": "Comparative analysis of malate dehydrogenases of Drosophila melanogaster.", "content": "Comparative analysis of malate dehydrogenases of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201525"} {"pmid": "4201527", "title": "The sialic acids of toad oviduct mucoprotein.", "content": "The sialic acids of toad oviduct mucoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201527"} {"pmid": "4201529", "title": "The production and purification of specific anti-soybean agglutinin antibody by affinity chromatography.", "content": "The production and purification of specific anti-soybean agglutinin antibody by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201529"} {"pmid": "4201528", "title": "Metabolism of sialic acids in toad oviduct.", "content": "Metabolism of sialic acids in toad oviduct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201528"} {"pmid": "4201530", "title": "Phosphotransacetylase from Bacillus subtilis: purification and physiological studies.", "content": "Phosphotransacetylase from Bacillus subtilis: purification and physiological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201530"} {"pmid": "4201531", "title": "Study of correlation between structural motility and reactivity of SH groups in alpha-amylase.", "content": "Study of correlation between structural motility and reactivity of SH groups in alpha-amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201531"} {"pmid": "4201532", "title": "Pig kidney particulate aminopeptidase. A zinc metalloenzyme.", "content": "Pig kidney particulate aminopeptidase. A zinc metalloenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201532"} {"pmid": "4201533", "title": "Acetolactate synthase of Pseudomonas aeruginosa I. Purification and allosteric properties.", "content": "Acetolactate synthase of Pseudomonas aeruginosa I. Purification and allosteric properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201533"} {"pmid": "4201534", "title": "Acetolactate synthase of Pseudomonas aeruginosa. II. Evidence for the presence of two nonidentical subunits.", "content": "Acetolactate synthase of Pseudomonas aeruginosa. II. Evidence for the presence of two nonidentical subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201534"} {"pmid": "4201543", "title": "Haloperidol in the treatment of nausea and vomiting due to cytotoxic drug administration.", "content": "Haloperidol in the treatment of nausea and vomiting due to cytotoxic drug administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201543"} {"pmid": "4201544", "title": "Anxiolytic effects of a new triazolobenzodiazepine, U-31,889.", "content": "Anxiolytic effects of a new triazolobenzodiazepine, U-31,889.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201544"} {"pmid": "4201545", "title": "Nitroglycerin: clinical pharmacological effects of form and route of administration.", "content": "Nitroglycerin: clinical pharmacological effects of form and route of administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201545"} {"pmid": "4201546", "title": "Clindamycin palmitate hydrochloride: a clinical trial in a pediatric office practice.", "content": "Clindamycin palmitate hydrochloride: a clinical trial in a pediatric office practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201546"} {"pmid": "4201547", "title": "Treatment of acute hypercalcemia with furosemide.", "content": "Treatment of acute hypercalcemia with furosemide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201547"} {"pmid": "4201548", "title": "Double-blind study of acetylcysteine-isoproterenol and saline-isoproterenol in non-hospitalized patients with asthma.", "content": "Double-blind study of acetylcysteine-isoproterenol and saline-isoproterenol in non-hospitalized patients with asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201548"} {"pmid": "4201549", "title": "Influence of intravenous administration of hypertonic solution on pain sensibility.", "content": "Influence of intravenous administration of hypertonic solution on pain sensibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201549"} {"pmid": "4201550", "title": "Comparison of various precipitin tests in the detection of alpha-fetoprotein in serum.", "content": "Comparison of various precipitin tests in the detection of alpha-fetoprotein in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201550"} {"pmid": "4201551", "title": "Macrophage-mediated resistance to intracellular infection induced by poly-L-glutamic acid.", "content": "Macrophage-mediated resistance to intracellular infection induced by poly-L-glutamic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201551"} {"pmid": "4201552", "title": "The stoichiometry of J chain in human secretory IgA.", "content": "The stoichiometry of J chain in human secretory IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201552"} {"pmid": "4201553", "title": "Recombination of the polypeptide chains of a Waldenström's IgM that binds IgG.", "content": "Recombination of the polypeptide chains of a Waldenström's IgM that binds IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201553"} {"pmid": "4201555", "title": "Quantitative phagocytosis by neutrophils. I. A new method with immune complexes.", "content": "Quantitative phagocytosis by neutrophils. I. A new method with immune complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201555"} {"pmid": "4201554", "title": "Migration inhibition of rat peritoneal cells induced by streptococcal mucopeptides. Characteristics of the reaction and properties of the mucopeptide preparations.", "content": "Migration inhibition of rat peritoneal cells induced by streptococcal mucopeptides. Characteristics of the reaction and properties of the mucopeptide preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201554"} {"pmid": "4201556", "title": "Quantitative phagocytosis by neutrophils. II. Release of the C5-cleaving enzyme and inhibition of phagocytosis by rheumatoid factor.", "content": "Quantitative phagocytosis by neutrophils. II. Release of the C5-cleaving enzyme and inhibition of phagocytosis by rheumatoid factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201556"} {"pmid": "4201557", "title": "Human antibody to dengue soluble complement-fixing (SCF) antigens.", "content": "Human antibody to dengue soluble complement-fixing (SCF) antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201557"} {"pmid": "4201558", "title": "Isolation of mucin from human submaxillary secretions.", "content": "Isolation of mucin from human submaxillary secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201558"} {"pmid": "4201560", "title": "Inversion injuries of the ankle.", "content": "Inversion injuries of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201560"} {"pmid": "4201559", "title": "Rosette formation by guinea pig thymocytes and thymus derived lymphocytes with rabbit red blood cells.", "content": "Rosette formation by guinea pig thymocytes and thymus derived lymphocytes with rabbit red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201559"} {"pmid": "4201561", "title": "Diverticula of the appendix.", "content": "Diverticula of the appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201561"} {"pmid": "4201562", "title": "Renal failure associated with the use of thio-tepa.", "content": "Renal failure associated with the use of thio-tepa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201562"} {"pmid": "4201571", "title": "The role of computers in the nuclear medicine laboratories.", "content": "The role of computers in the nuclear medicine laboratories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201571"} {"pmid": "4201570", "title": "Cholesterol gallstones.", "content": "Cholesterol gallstones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201570"} {"pmid": "4201572", "title": "Whole-body counting.", "content": "Whole-body counting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201572"} {"pmid": "4201573", "title": "Acute diverticulitis.", "content": "Acute diverticulitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201573"} {"pmid": "4201575", "title": "Safety tests of orgotein, an antiinflammatory protein.", "content": "Safety tests of orgotein, an antiinflammatory protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201575"} {"pmid": "4201565", "title": "Effect of osmotic concentration and pH on sclerotia and cleistothecia production in alkaline and fertile soil Aspergilli.", "content": "Effect of osmotic concentration and pH on sclerotia and cleistothecia production in alkaline and fertile soil Aspergilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201565"} {"pmid": "4201576", "title": "An attempt to classify the toxic proteins of Elapidae and Hydrophiidae venoms.", "content": "An attempt to classify the toxic proteins of Elapidae and Hydrophiidae venoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201576"} {"pmid": "4201581", "title": "On the natural history of coccidial infections in feeder cattle.", "content": "On the natural history of coccidial infections in feeder cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201581"} {"pmid": "4201583", "title": "Influence of fixation on physiological properties of frog gastric mucosa.", "content": "Influence of fixation on physiological properties of frog gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201583"} {"pmid": "4201584", "title": "Metabolism of 14C-histamine in goats and pigs treated with aminoguanidine.", "content": "Metabolism of 14C-histamine in goats and pigs treated with aminoguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201584"} {"pmid": "4201585", "title": "On the elimination of transfused heparin-induced diamine oxidase (DAO) activity in rabbits.", "content": "On the elimination of transfused heparin-induced diamine oxidase (DAO) activity in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201585"} {"pmid": "4201586", "title": "Effect of organ removal or damage on the heparin-induced diamine oxidase (DAO) response in rat and rabbit.", "content": "Effect of organ removal or damage on the heparin-induced diamine oxidase (DAO) response in rat and rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201586"} {"pmid": "4201587", "title": "Application of gas chromatography, mass spectrometry, and computer methods in clinical biochemistry.", "content": "Application of gas chromatography, mass spectrometry, and computer methods in clinical biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201587"} {"pmid": "4201574", "title": "The outcome of stroke at hospital discharge in New York City blacks.", "content": "The outcome of stroke at hospital discharge in New York City blacks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201574"} {"pmid": "4201588", "title": "Studies on the methylation of mercuric chloride by pure cultures of bacteria and fungi.", "content": "Studies on the methylation of mercuric chloride by pure cultures of bacteria and fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201588"} {"pmid": "4201590", "title": "Monomolecular films of bacteriochlorophyll and derivatives at an air-water interface: surface and spectral properties.", "content": "Monomolecular films of bacteriochlorophyll and derivatives at an air-water interface: surface and spectral properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201590"} {"pmid": "4201582", "title": "Australia antigen and circulating antibodies in chronic aggressive hepatitis.", "content": "Australia antigen and circulating antibodies in chronic aggressive hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201582"} {"pmid": "4201594", "title": "Mucolipidosis 3 (pseudo-Hurler polydystrophy): cytological and ultrastructural observations of cultured fibroblast cells.", "content": "Mucolipidosis 3 (pseudo-Hurler polydystrophy): cytological and ultrastructural observations of cultured fibroblast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201594"} {"pmid": "4201595", "title": "Relief of musculoskeletal and associated psychopathological symptoms with meprobamate and aspirin: a controlled study.", "content": "Relief of musculoskeletal and associated psychopathological symptoms with meprobamate and aspirin: a controlled study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201595"} {"pmid": "4201596", "title": "Controlled evaluation of a new topical corticosteroid in psoriasis.", "content": "Controlled evaluation of a new topical corticosteroid in psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201596"} {"pmid": "4201598", "title": "Diazepam (calmpose) in eclampsia: a preliminary report of 16 cases.", "content": "Diazepam (calmpose) in eclampsia: a preliminary report of 16 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201598"} {"pmid": "4201597", "title": "A double-blind comparison of active and inert douches in vaginitis.", "content": "A double-blind comparison of active and inert douches in vaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201597"} {"pmid": "4201599", "title": "Safety and effectiveness of haloperidol for mentally retarded behaviorally disordered and hyperkinetic patients.", "content": "Safety and effectiveness of haloperidol for mentally retarded behaviorally disordered and hyperkinetic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201599"} {"pmid": "4201600", "title": "The effect of lithium and other antidepressant medications on the autonomic nervous system.", "content": "The effect of lithium and other antidepressant medications on the autonomic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201600"} {"pmid": "4201601", "title": "Serum levels of anhydrous ampicillin administered orally in normal infants.", "content": "Serum levels of anhydrous ampicillin administered orally in normal infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201601"} {"pmid": "4201593", "title": "Disposition of arabinosylcytosine (NSC-63878) and 6-THIOGUANINE (NSC-752) in solid L1210 leukemia tumor-bearing mice.", "content": "Disposition of arabinosylcytosine (NSC-63878) and 6-THIOGUANINE (NSC-752) in solid L1210 leukemia tumor-bearing mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201593"} {"pmid": "4201609", "title": "Studies of Anatrichosoma (Nematoda: Trichinellida) with descriptions of Anatrichosoma rhina sp. n. and Anatrichosoma nacepobi sp. n. from the nasal mucosa of Macaca mulatta.", "content": "Studies of Anatrichosoma (Nematoda: Trichinellida) with descriptions of Anatrichosoma rhina sp. n. and Anatrichosoma nacepobi sp. n. from the nasal mucosa of Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201609"} {"pmid": "4201611", "title": "An improved method for the scanning electron microscopy of spermatozoa.", "content": "An improved method for the scanning electron microscopy of spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201611"} {"pmid": "4201610", "title": "Advances in radiotherapy--improved results following treatment with high energy electrons and 25 MEV X-ray. 1.", "content": "Advances in radiotherapy--improved results following treatment with high energy electrons and 25 MEV X-ray. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201610"} {"pmid": "4201612", "title": "Metabolic profile of a new immunosuppressive agent, oxisuran: binding, RE stimulation, drug interaction.", "content": "Metabolic profile of a new immunosuppressive agent, oxisuran: binding, RE stimulation, drug interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201612"} {"pmid": "4201613", "title": "Diffusive and electrostatic effects with insolubilized enzymes subject to substrate inhibition.", "content": "Diffusive and electrostatic effects with insolubilized enzymes subject to substrate inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201613"} {"pmid": "4201618", "title": "Near-cytotoxic gold salt therapy in long standing drug-refractory rheumatoid arthritis. A prospective investigation.", "content": "Near-cytotoxic gold salt therapy in long standing drug-refractory rheumatoid arthritis. A prospective investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201618"} {"pmid": "4201623", "title": "A qualitative demonstration of the degradation of folic acid by Pseudomonas fluorescens UK-1.", "content": "A qualitative demonstration of the degradation of folic acid by Pseudomonas fluorescens UK-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201623"} {"pmid": "4201624", "title": "Antigenic relationship between lysozymes and its use in isolation and purification of this type of enzyme.", "content": "Antigenic relationship between lysozymes and its use in isolation and purification of this type of enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201624"} {"pmid": "4201626", "title": "Cartilaginous transformation of the aortic valve.", "content": "Cartilaginous transformation of the aortic valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201626"} {"pmid": "4201620", "title": "Beta-fetoprotein as a thymus-dependent factor in humans.", "content": "Beta-fetoprotein as a thymus-dependent factor in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201620"} {"pmid": "4201627", "title": "Fibrin degradation products in the postoperative period. Evaluation of a new latex agglutination method.", "content": "Fibrin degradation products in the postoperative period. Evaluation of a new latex agglutination method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201627"} {"pmid": "4201619", "title": "Development of nonspecific factors of antiinfection resistance of monkeys in ontogenesis.", "content": "Development of nonspecific factors of antiinfection resistance of monkeys in ontogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201619"} {"pmid": "4201628", "title": "Endocarditis caused by Bacillus subtilis.", "content": "Endocarditis caused by Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201628"} {"pmid": "4201629", "title": "Studies on the variables in Rh slide testing.", "content": "Studies on the variables in Rh slide testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201629"} {"pmid": "4201630", "title": "Miliary tuberculosis.", "content": "Miliary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201630"} {"pmid": "4201632", "title": "Studies on the bacteriophage of a natural lysogenic Mycobacterium fortuitum.", "content": "Studies on the bacteriophage of a natural lysogenic Mycobacterium fortuitum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201632"} {"pmid": "4201631", "title": "Clinical significance of casual isolation of acid-fast organisms from sputum of tuberculous patients.", "content": "Clinical significance of casual isolation of acid-fast organisms from sputum of tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201631"} {"pmid": "4201633", "title": "Letter: Correlation of lymphocyte transformation with tuberculin skin-test sensitivity.", "content": "Letter: Correlation of lymphocyte transformation with tuberculin skin-test sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201633"} {"pmid": "4201635", "title": "Tropical problems in nutrition.", "content": "Tropical problems in nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201635"} {"pmid": "4201634", "title": "Pseudomonas aeruginosa resistant to carbenicillin and gentamicin. Epidemiologic and clinical aspects in a cancer center.", "content": "Pseudomonas aeruginosa resistant to carbenicillin and gentamicin. Epidemiologic and clinical aspects in a cancer center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201634"} {"pmid": "4201636", "title": "Urate secretion in man: the pyrazinamide suppression test.", "content": "Urate secretion in man: the pyrazinamide suppression test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201636"} {"pmid": "4201637", "title": "Neisseria gonorrhoeae auxotyping: differentiation of clinical isolates based on growth responses on chemically defined media.", "content": "Neisseria gonorrhoeae auxotyping: differentiation of clinical isolates based on growth responses on chemically defined media. A system is described for differentiating clinïcal isolates of Neisseria gonorrhoeae based on their growth or absence of growth on a set of 11 chemically defined agar media. The complete medium, NEDA, contains all of the compounds required for gonococcal growth; but isolates differ in their ability to grow on NEDA from which selected compounds are individually omitted. The differential compounds include L-proline, L-arginine, L-ornithine, L-methionine, hypoxanthine, uracil, thiamine, and thiamine pyrophosphate. A distinctive pattern of growth responses on the standard media defines an auxotype. Twenty auxotypes were found among a group of 251 gonococci which were isolated from patients examined in the clinics of one city during a 3-month span of time. Another collection of 74 strains from several different countries yielded two additional auxotypes. The stability of the nutritional requirements on which the auxotyping depends was verified in two ways. Cultures isolated from different anatomic sites of a patient or from sexual partners represented the same auxotype, as did cultures which were repeatedly isolated from cases of presumptive treatment failures. Also, the auxotypes of gonococci remained the same after numerous subcultures. The reproducibility of results and the variety and number of auxotypes indicate the potential value of the auxotyping system as an epidemiological tool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201637"} {"pmid": "4201638", "title": "Detection and identification of diagnostic Histoplasma capsulatum precipitates by counterelectrophoresis.", "content": "Detection and identification of diagnostic Histoplasma capsulatum precipitates by counterelectrophoresis. Studies were carried out to develop and evaluate a counterelectrophoresis (CEP) technique for the rapid and specific identification of the diagnostically important histoplasmosis H and M precipitin bands. Well-defined and centrally located precipitin bands were produced by using a discontinuous buffer system and a gel matrix composed of agarose and ionagar no. 2. A template was devised which allowed the selective identification of the H and M precipitins. Comparative evaluations were performed with the microimmunodiffusion (ID) and complement fixation tests. In 52 sera from persons with histoplasmosis, either the H or M precipitin, or both, were identified in 42 (81%) of the cases with the CEP technique and in 43 (83%) with the ID test. With sera from 28 persons with heterologous diseases, the CEP technique, like the ID test, failed to react. The specificity of the CEP technique was dependent upon the use of the identity template. The CEP technique is recommended for routine use in laboratories testing moderate numbers of sera. It provides accurate and reproducible results within 90 min, in contrast to the ID test, which requires 18 to 24 h.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201638"} {"pmid": "4201639", "title": "Specific immunodiffusion test for blastomycosis.", "content": "Specific immunodiffusion test for blastomycosis. A specific immunodiffusion test for blastomycosis has been developed. The test permitted the detection of approximately 80% of 113 proven cases of blastomycosis. Two diagnostically important precipitins designated A and B were frequently recognized in patients with blastomycosis. Routine use of reference sera containing the A and B precipitins in immunodiffusion tests would permit the specific diagnosis of blastomycosis without the need for parallel tests with coccidioidin and histoplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201639"} {"pmid": "4201640", "title": "Variation in colonial morphology of Neisseria gonorrhoeae after growth on media containing antimicrobial agents.", "content": "Variation in colonial morphology of Neisseria gonorrhoeae after growth on media containing antimicrobial agents. Stable colonial types 1, 2, 3, and 4 were prepared from eight strains of Neisseria gonorrhoeae. Four of the strains, termed laboratory strains, had been transferred over 100 times; three strains, termed clinical strains, were transferred only three to five times after isolation from patients, and one stabilized clinical strain was transferred purposefully 30 times after isolation from a patient. Colonial types of the three categories were grown on four media containing the following agents at the level used in diagnostic media: (i) vancomycin, colistin, and nystatin; (ii) these antibiotics plus trimethoprim lactate; (iii) trimethoprim lactate alone; and (iv) a control with no antimicrobial agents. When grown on media containing the antimicrobial agents, colonial types 1, 2, and 3 of all strains showed specific and consistent changes that precluded accurate identification of the types. In general, the colonies were smaller, more dense to transmission of light, and more granular than colonies grown on control medium. More colonies showed these type changes in the clinical strains and on media containing trimethoprim lactate. Colonies of type 4 showed little or no change. The changes in colonial morphology of types 1, 2, and 3 were pronounced enough to make colony typing difficult if the antimicrobial agents, particularly trimethoprim lactate, were present in media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201640"} {"pmid": "4201641", "title": "In vitro studies with Modoc virus in Vero cells: plaque assay and kinetics of growth, neutralization, and thermal inactivation.", "content": "In vitro studies with Modoc virus in Vero cells: plaque assay and kinetics of growth, neutralization, and thermal inactivation. A sensitive and quantitative assay system is described for plaquing Modoc virus in Vero cells. Neutralizing antibodies to Modoc virus could be detected by using this in vitro system by their interference with viral plaque formation. Virus was readily neutralized within 30 min at 37 C by a 1:10 dilution of hyperimmune hamster serum. The rate of neutralization and the total amount of virus neutralized was not altered significantly by the addition of 20 U of guinea pig complement to the hyperimmune hamster serum. A study of the growth of Modoc virus in Vero cells is also presented. After an initial latent period of 20 h, viral titer increased exponentially for 20 h. By 83 h after infection, 8,000 plaque-forming units of virus were detected per cell. The stability of viral infectivity in phosphate-buffered saline at pH 7.4 was evaluated. No reduction in viral titer was detected after 3 days at 7 or 22 C. A continuous decrease in infectivity at 37 C was observed, however, throughout the observation period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201641"} {"pmid": "4201642", "title": "Microtissue culture plaque assay for Herpesvirus saimiri.", "content": "Microtissue culture plaque assay for Herpesvirus saimiri. A microtissue culture method for the plaque assay of Herpesvirus saimiri has been developed. Virus titrations carried out in Microtest II tissue culture plates (Falcon) yielded reproducible results that agreed well with those obtained by employing macrocultures. The described method is quantitative, reproducible, economical, and suitable for routine assay of large numbers of virus samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201642"} {"pmid": "4201643", "title": "Sensitivity of three selected bacterial species to ozone.", "content": "Sensitivity of three selected bacterial species to ozone. THE MINIMAL LETHAL CONCENTRATION OF OZONE IN WATER WAS DETERMINED FOR THREE BACTERIAL SPECIES: Escherichia coli, Bacillus cereus, and Bacillus megaterium. A contact period of 5 min was selected. The lethal threshold concentration for the cells of B. cereus was 0.12 mg/liter while that for E. coli and B. megaterium was 0.19 mg/liter. Low concentrations of ozone were ineffective when organic matter was present to interfere with the action of ozone on the bacterial cells. Also determined during the study was the sensitivity of spores of B. cereus and B. megaterium to ozone in water. The threshold concentration required to kill the spores of both species was 2.29 mg/liter. The cells and spores of these organisms exhibited the \"all-or-none\" die-away phenomenon normally associated with ozone treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201643"} {"pmid": "4201645", "title": "Modification of the starch block electrophoresis method for the preparation of immunoglobulin A from multiple myeloma sera on a large scale.", "content": "Modification of the starch block electrophoresis method for the preparation of immunoglobulin A from multiple myeloma sera on a large scale. Separation of immunoglobulin A from a large sample of human serum from patients with multiple myeloma was done by utilizing a large zone electrophoresis apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201645"} {"pmid": "4201646", "title": "Clinical evaluation of sodium amylosulfate in human blood cultures.", "content": "Clinical evaluation of sodium amylosulfate in human blood cultures. Sodium amylosulfate was shown to be a useful anticoagulant additive for increased isolation of bacteria from clinical blood cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201646"} {"pmid": "4201647", "title": "Temperature adaptability of psychrotrophic Pseudomonas.", "content": "Temperature adaptability of psychrotrophic Pseudomonas. The rate of oxidation of glucose and alanine at low temperatures by washed cells of psychrotrophic strains of Pseudomonas is related to growth temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201647"} {"pmid": "4201648", "title": "Comparison of atmospheric conditions for culture of clinical specimens of Neisseria gonorrhoeae.", "content": "Comparison of atmospheric conditions for culture of clinical specimens of Neisseria gonorrhoeae. We cultured 55 clinical specimens of Neisseria gonorrhoeae in the following atmospheric conditions: (i) 10% carbon dioxide in a CO(2) incubator; (ii) a candle extinction jar; (iii) an air convection incubator; and (iv) an anaerobic jar without added CO(2). The number and size of colonies growing on modified Thayer-Martin medium were evaluated after incubation of cultures for 24 and 48 h at 36 C. After 24 h, the specimens from the candle extinction jar had the greatest number and size of colonies, but after 48 h growth was approximately equal for specimens from the candle jar and the CO(2) incubator. Only 19 of 55 specimens grew in the air convention incubator. None of 55 clinical specimens or of 10 laboratory strains grew anaerobically. Development of colonial morphology for colony types 1, 2, 3, and 4 was studied at 24 h on a base medium that contained no hemoglobin. The relative numbers of the four colony types in specimens were comparable after 24 h of incubation in any of the three atmospheric conditions under which growth occurred, but the different types were distinguished most readily when grown in the candle extinction jar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201648"} {"pmid": "4201644", "title": "Lytic activity of vibrio phages on strains of Vibrio fetus isolated from man and animals.", "content": "Lytic activity of vibrio phages on strains of Vibrio fetus isolated from man and animals. Five phages isolated from lysogenic strains of Vibrio fetus var. venerealis and two from V. fetus var. intestinalis were tested for lytic activity on 95 V. fetus strains from various animal and human hosts. In addition, virion and plaque morphology of the seven phages were compared. Electron micrographs showed that all were the kite-tailed variety with minor variations in head and tail dimensions. Plaques of V45 and V2 were small, clear and irregular; those of V3, V8, and V19 were large, clear and regular at the edge; the plaques of V16 and V20 were intermediate in size, clear, and very irregular at the edge with satellite plaques. The number of strains lysed by one or more phages were as follows: 29 of 30 from cattle; 7 of 11 from sheep; 1 of 5 from pigs; 1 of 1 from a monkey; and 33 of 42 from human hosts. Four natural groups of phages were derived by statistical measures of percentage of similarity in lytic activity. Group III lysed more strains (46 of 95) than any of the others. Twenty-five strains were lysed by group IV, 23 strains by group I, and 19 strains by group II. Results of this study indicate that phage typing should be a practical supplement to other differential tests for V. fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201644"} {"pmid": "4201650", "title": "Effect of glutaraldehyde on cell viability, triphenyltetrazolium reduction, oxygen uptake, and beta-galactosidase activity in Escherichia coli.", "content": "Effect of glutaraldehyde on cell viability, triphenyltetrazolium reduction, oxygen uptake, and beta-galactosidase activity in Escherichia coli. Acid (pH 5) and alkaline (pH 8.5) glutaraldehyde solutions were compared for their effects on cell viability, oxygen uptake, and beta-galactosidase activities in Escherichia coli. The action of glutaraldehyde at pH 7 on dehydrogenase activity was also studied. Dehydrogenase activity was inhibited at aldehyde concentrations which had little effect on cell viability. In contrast, oxygen uptake and beta-galactosidase activity took place in cells killed by acid or alkaline glutaraldehyde. The effect of glutaraldehyde on dehydrogenase activity and beta-galactosidase activity of disrupted suspensions was also investigated. The dialdehyde was considerably less inhibitory to these enzyme systems than to those of whole cells, and it is thus feasible that the results with whole cells are a consequence of its interaction with, and strengthening of, the outer cell surface, thereby preventing ready access of substrate to enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201650"} {"pmid": "4201649", "title": "Microtiter solid-phase radioimmunoassay for hepatitis B antigen.", "content": "Microtiter solid-phase radioimmunoassay for hepatitis B antigen. A micro-solid-phase radioimmunoassay (micro-SPRIA) for hepatitis B antigen (HB Ag) was developed for use with microtiter serological equipment. Radiolabeled immunoglobulin G was prepared from human and animal sera containing hepatitis B antibody (HB Ab); it was not necessary to isolate specific HB Ab by immunochemical means. A micro-SPRIA prepared with guinea pig reagents was approximately as sensitive as the AusRIA radioimmunoassay, but, like the AusRIA test, yielded false positive results. A micro-SPRIA prepared with human reagents was slightly less sensitive but did not yield false positive results. These micro-SPRIA tests offer several advantages, including conservation of reagents, adaptability to other antigen-antibody systems, ease of performance (especially when testing large numbers of specimens), and economy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201649"} {"pmid": "4201652", "title": "Peroxidase diffusion in the normal sensory retina.", "content": "Peroxidase diffusion in the normal sensory retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201652"} {"pmid": "4201653", "title": "Treatment of central nervous system leukemia with intrathecal cytosine arabinoside.", "content": "Treatment of central nervous system leukemia with intrathecal cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201653"} {"pmid": "4201654", "title": "Controlled prospective trial of Pseudomonas aeruginosa vaccine in children with acute leukemia.", "content": "Controlled prospective trial of Pseudomonas aeruginosa vaccine in children with acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201654"} {"pmid": "4201655", "title": "Yolk sac tumor (endodermal sinus tumor) and alpha-fetoprotein. A report of three cases.", "content": "Yolk sac tumor (endodermal sinus tumor) and alpha-fetoprotein. A report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201655"} {"pmid": "4201657", "title": "Congenital diverticulum of the left ventricle associated with hypoplastic right ventricle and ventricular septal defect.", "content": "Congenital diverticulum of the left ventricle associated with hypoplastic right ventricle and ventricular septal defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201657"} {"pmid": "4201656", "title": "The effect of clinical pharmacy services on patients with essential hypertension.", "content": "The effect of clinical pharmacy services on patients with essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201656"} {"pmid": "4201658", "title": "Editorial: Nitrates in the prophylactic treatment of angina pectoris.", "content": "Editorial: Nitrates in the prophylactic treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201658"} {"pmid": "4201659", "title": "Influence of albumin on the hepatic uptake of unconjugated bilirubin.", "content": "Influence of albumin on the hepatic uptake of unconjugated bilirubin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201659"} {"pmid": "4201661", "title": "Suppression of plasma renin by atherogenic levels of serum cholesterol in rabbits.", "content": "Suppression of plasma renin by atherogenic levels of serum cholesterol in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201661"} {"pmid": "4201660", "title": "Relationship between plasma cortisol and peak expiratory flow rat in exercise-induced asthma and the effect of sodium cromoglycate.", "content": "Relationship between plasma cortisol and peak expiratory flow rat in exercise-induced asthma and the effect of sodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201660"} {"pmid": "4201662", "title": "Induction of glycoprotein mating factors in diploid yeast of Hansenula wingei by vanadium salts or chelating agents.", "content": "Induction of glycoprotein mating factors in diploid yeast of Hansenula wingei by vanadium salts or chelating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201662"} {"pmid": "4201663", "title": "Non-histone proteins. The effect of nuclear washes and comparison of metaphase and interphase chromatin.", "content": "Non-histone proteins. The effect of nuclear washes and comparison of metaphase and interphase chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201663"} {"pmid": "4201664", "title": "Binding of a tritiated thyrotropin-releasing factor to a prolactin secreting clonal cell line (GH3).", "content": "Binding of a tritiated thyrotropin-releasing factor to a prolactin secreting clonal cell line (GH3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201664"} {"pmid": "4201665", "title": "Transition-state analogs of an aliphatic amidase.", "content": "Transition-state analogs of an aliphatic amidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201665"} {"pmid": "4201666", "title": "Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus.", "content": "Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201666"} {"pmid": "4201667", "title": "Inhibition of leucocyte migration by tumour-associated antigens of the colon and rectum.", "content": "Inhibition of leucocyte migration by tumour-associated antigens of the colon and rectum. The test of leucocyte migration inhibition has been used to detect lymphocyte sensitization to tumour-associated antigens of the colon and rectum. The procedure for the isolation of antigens from colorectal adenocarcinomata and normal colonic mucosa is described. The circulating lymphocytes of 22 patients suffering from colorectal adenocarcinomata of various stages have been examined and compared with the results obtained for identical studies performed on the peripheral lymphocytes of 15 control subjects. Sensitization of lymphocytes to tumour antigen was demonstrated in 15 of the 22 patients when culture was performed in homologous AB serum. Of these 15 patients only six showed inhibition of leucocyte migration in the presence of tumour extract when culture was performed in autologous serum. These observations would suggest the presence of factors in the serum of such patients which may prevent the expression of cellular immunity to tumour antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201667"} {"pmid": "4201668", "title": "Gluconeogenesis from amino acids in mature wether sheep.", "content": "Gluconeogenesis from amino acids in mature wether sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201668"} {"pmid": "4201669", "title": "Studies of the protein requirement of the neonatal rat.", "content": "Studies of the protein requirement of the neonatal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201669"} {"pmid": "4201670", "title": "Differential effects of protein-calorie restriction and subsequent repletion on neuronal and nonneuronal components of cerebral cortex in newborn rats.", "content": "Differential effects of protein-calorie restriction and subsequent repletion on neuronal and nonneuronal components of cerebral cortex in newborn rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201670"} {"pmid": "4201671", "title": "Letter: Selenium and dental caries susceptibility.", "content": "Letter: Selenium and dental caries susceptibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201671"} {"pmid": "4201672", "title": "Conformation of sodium cromolyn in aqueous solution using light scattering and magnetic birefringence.", "content": "Conformation of sodium cromolyn in aqueous solution using light scattering and magnetic birefringence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201672"} {"pmid": "4201673", "title": "Partial purification of antigen E from mixed stems and leaves of short ragweed plant.", "content": "Partial purification of antigen E from mixed stems and leaves of short ragweed plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201673"} {"pmid": "4201674", "title": "Assay of thiotepa by PMR spectrometry.", "content": "Assay of thiotepa by PMR spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201674"} {"pmid": "4201678", "title": "Concentration of penicillin V and tetracycline in maxillary sinus secretion after repeated doses.", "content": "Concentration of penicillin V and tetracycline in maxillary sinus secretion after repeated doses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201678"} {"pmid": "4201679", "title": "Shift in viral strains of hepatitis B in Stockholm as reflected by subtypes of hepatitis B antigen.", "content": "Shift in viral strains of hepatitis B in Stockholm as reflected by subtypes of hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201679"} {"pmid": "4201680", "title": "Hepatitis-associated antigen, subtypes D and Y. An epidemiological and clinical evaluation.", "content": "Hepatitis-associated antigen, subtypes D and Y. An epidemiological and clinical evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201680"} {"pmid": "4201681", "title": "Experimental alcoholic hepatitis: a new primate model.", "content": "Experimental alcoholic hepatitis: a new primate model. Research into the pathogenesis of alcoholic cirrhosis has suffered from the lack of an animal model of alcoholic hepatitis, considered by many to be the link between alcoholic fatty liver and cirrhosis. The entire constellation of histologic features characteristic of alcoholic hepatitis has been produced for the first time in baboons by administration of ethanol with a nutritionally adequate diet. This includes fat, necrosis. inflammation, alcoholic hyaline, fibrosis, and central hyaline sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201681"} {"pmid": "4201682", "title": "Phosphate-induced protein chromatography.", "content": "Phosphate-induced protein chromatography. High phosphate concentration is shown to cause a large proportion of the proteins of a cell-free extract of Escherichia coli to bind to agarose columns to which L-valine is attached. With a decreasing concentration gradient of potassium phosphate, the proteins elute in relation to their solubility in concentrated ammonium sulfate. This column technique appears to provide a general tool for the purification of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201682"} {"pmid": "4201683", "title": "Unstable angina.", "content": "Unstable angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201683"} {"pmid": "4201685", "title": "The pattern of epilepsy in Uganda.", "content": "The pattern of epilepsy in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201685"} {"pmid": "4201686", "title": "Pathogenic leptospira isolated from toad kidneys.", "content": "Pathogenic leptospira isolated from toad kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201686"} {"pmid": "4201689", "title": "Comparative aspects of morphogenesis in three prokaryotic genera.", "content": "Comparative aspects of morphogenesis in three prokaryotic genera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201689"} {"pmid": "4201684", "title": "Readiness for synthesis of red and brown pigments in the imaginal eye disks of Drosophila melanogaster.", "content": "Readiness for synthesis of red and brown pigments in the imaginal eye disks of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201684"} {"pmid": "4201690", "title": "Nitrogen fixation by photosynthetic microorganisms.", "content": "Nitrogen fixation by photosynthetic microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201690"} {"pmid": "4201691", "title": "Biology of Trypanosoma cruzi.", "content": "Biology of Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201691"} {"pmid": "4201692", "title": "Characterization of circadian oscillations in alanine dehydrogenase activity in non-dividing populations of Euglena gracilis (Z).", "content": "Characterization of circadian oscillations in alanine dehydrogenase activity in non-dividing populations of Euglena gracilis (Z).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201692"} {"pmid": "4201693", "title": "Studies on the biochemical basis of oxygen toxicity.", "content": "Studies on the biochemical basis of oxygen toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201693"} {"pmid": "4201694", "title": "Antigenic variants of influenza B virus.", "content": "Antigenic variants of influenza B virus. From 1967 to 1971 little antigenic variation was detected in the prevalent influenza B viruses but in December 1972 a new antigenic variant of influenza B was isolated in Hong Kong from sporadic cases of influenza. The new variant, B/Hong Kong/5/72, possessed a haemagglutinin antigen which showed considerable antigenic differences from that of former influenza B strains while its neuraminidase antigen was closely related to that of the earlier, 1967-71, isolates. The B/Hong Kong/5/72 variant became the predominant influenza B strain in the United Kingdom by early summer 1973, and in both the United Kingdom and Japan this strain was associated with outbreaks of influenza. Strains antigenically intermediate between the 1967-71 isolates and B/Hong Kong/5/72 were isolated in a number of countries, often concurrently with B/Hong Kong/5/72-like strains.Serological studies indicated that antibody to B/Hong Kong/5/72 was infrequent in the populations in the United Kingdom and the U.S.A., suggesting the possibility of future epidemic activity associated with the new variant. In addition, conventional inactivated influenza vaccines containing the older influenza B isolates given to volunteers stimulated poor antibody responses to B/Hong Kong/5/72 virus. These studies indicate the desirability of immunizing high risk patients against B/Hong Kong/5/72-like viruses before the coming influenza season. Vaccine containing the new variant influenza B strain are currently available in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201694"} {"pmid": "4201695", "title": "Specificity of cell wall labeling with triated diaminopimelic acid in Bacillus subtilis.", "content": "Specificity of cell wall labeling with triated diaminopimelic acid in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201695"} {"pmid": "4201696", "title": "Psychotrophic gram-positive bacteria: temperature effects on growth and solute uptake.", "content": "Psychotrophic gram-positive bacteria: temperature effects on growth and solute uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201696"} {"pmid": "4201697", "title": "Antigenic comparison between in vivo and in vitro grown tubercle bacilli.", "content": "Antigenic comparison between in vivo and in vitro grown tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201697"} {"pmid": "4201698", "title": "Control of tartrate utilization in Aspergillus flavus.", "content": "Control of tartrate utilization in Aspergillus flavus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201698"} {"pmid": "4201699", "title": "The phyloantigenic position of nocardiae revealed by examination of cytoplasmic antigens.", "content": "The phyloantigenic position of nocardiae revealed by examination of cytoplasmic antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201699"} {"pmid": "4201700", "title": "Favorable effects in vitro and in vivo of two clinical isolates of Pseudomonas aeruginosa on nutritionally deficient Staphylococcus aureus strains.", "content": "Favorable effects in vitro and in vivo of two clinical isolates of Pseudomonas aeruginosa on nutritionally deficient Staphylococcus aureus strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201700"} {"pmid": "4201703", "title": "Distribution along X-chromosome of recessive lethals induced by direct and indirect X-radiation effect in Drosophila.", "content": "Distribution along X-chromosome of recessive lethals induced by direct and indirect X-radiation effect in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201703"} {"pmid": "4201702", "title": "Supplementary parenteral nutrition in patients with malignant disease. Guidelines to patient selection.", "content": "Supplementary parenteral nutrition in patients with malignant disease. Guidelines to patient selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201702"} {"pmid": "4201705", "title": "Australia (hepatitis-associated) antigen in urban endemic hepatitis at Poona.", "content": "Australia (hepatitis-associated) antigen in urban endemic hepatitis at Poona.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201705"} {"pmid": "4201704", "title": "Effect of phenobarbital and DL-ethionine on 4-(dimethylamino)azobenzene-metabolizing enzymes and carcinogenesis.", "content": "Effect of phenobarbital and DL-ethionine on 4-(dimethylamino)azobenzene-metabolizing enzymes and carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201704"} {"pmid": "4201707", "title": "Analysis of the schedule of DNA replication in heat-synchronized Tetrahymena.", "content": "Analysis of the schedule of DNA replication in heat-synchronized Tetrahymena. The temporal schedule of DNA replication in heat-synchronized Tetrahymena was studied by autoradiographic and cytofluorometric methods. It was shown that some cells, which were synchronized by selection of individual dividing cells or by temporary thymidine starvation, incorporated [(3)H]thymidine into macronuclei in a periodic fashion during the heat-shock treatment. It was concluded that supernumerary S periods occurred while cell division was blocked by high temperature. The proportion of cells which initiated supernumerary S periods was found to be dependent on the duration of the heat-shock treatment and on the cell cycle stage when the first heat shock was applied. Cytofluorometric measurements of Feulgen-stained macronuclei during the heat-shock treatment indicated that the DNA complement of these cells was substantially increased and probably duplicated during the course of each S period. Estimates of DNA content also suggested that the rate of DNA synthesis progressively declined during long heat-shock treatments. These results indicate that the mechanism which brings about heat-induced division synchrony is not an interruption of the process of DNA replication. Further experiments were concerned with the regulation of DNA synthesis during the first synchronized division cycle. It was shown that participation in DNA synthesis at this time increased as more cells were able to conclude the terminal S period during the preceding heat-shock treatment. It is suggested that a discrete period of time is necessary after the completion of DNA synthesis before another round of DNA synthesis can be initiated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201707"} {"pmid": "4201706", "title": "The relationship of concanavalin A binding to lectin-initiated cell agglutination.", "content": "The relationship of concanavalin A binding to lectin-initiated cell agglutination. We have investigated the relationship of concanavalin. A binding to the cell surface of normal and transformed cells and the subsequent agglutination of the transformed cells. At room temperature almost no differences could be detected in agglutinin binding between transformed and untransformed cells. At 0 degrees C, however, where endocytosis was negligible, the transformed cells bound three times more agglutinin. However, transformed cells and trypsin-treated normal cells do not agglutinate at 0 degrees C although the amounts of agglutinin bound at 0 degrees C are sufficient to permit agglutination when such cells are shifted up to room temperature. Both transformed and trypsin-treated normal cells show a marked increase in agglutination at 15 degrees C as compared to agglutination at 0 degrees C. From this, as well as the observation that mild glutaraldehyde fixation of the cell surface inhibited agglutination but not agglutinin binding, it was concluded that concanavalin A-mediated cell agglutination requires free movement of the agglutinin receptor sites within the plane of the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201706"} {"pmid": "4201708", "title": "Localization of polysome-bound albumin and serine dehydratase in rat liver cell fractions.", "content": "Localization of polysome-bound albumin and serine dehydratase in rat liver cell fractions. The polysomes involved in albumin and serine dehydratase synthesis were identified and localized by the binding to rat liver polysomes of anti-rat serum albumin and anti-serine dehydratase [(125)I]Fab dimer and monomer. Techniques were developed for the isolation of undegraded free and membrane-bound polysomes and for the preparation of [(125)I]Fab monomers and dimers from the IgG obtained from the antisera to the two proteins, rat serum albumin and serine dehydratase. The distribution of anti-rat serum albumin [(125)I]Fab dimer in the polysome profile is in accordance with the size of polysomes that are expected to be synthesizing albumin. By direct precipitation, it has been demonstrated that nascent chains isolated from the membrane-bound polysomes by puromycin were precipitated by anti-rat serum albumin-IgG at a level of 5-6 times those released from free polysomes. Anti-rat serum albumin-[(125)I]Fab dimer reacted with membrane-bound polysomes almost exclusively compared to the binding of nonimmune, control [(125)I]Fab dimer; a significant degree of binding of anti-rat serum albumin-[(125)I]Fab to free polysomes was also obtained. The [(125)I]Fab dimer made from normal control rabbit serum does not react with polysomes from liver at all and this preparation will not interact with polysomes extracted from tissues that do not synthesize rat serum albumin. Both anti-serine dehydratase-[(125)I]Fab monomer and dimer react with free and bound polysomes from livers of animals fed a chow diet or those fed a high 90% protein diet and given glucagon. In the latter instance, however, it is clear that the majority of the binding occurs to the bound polysomes. Furthermore, the specificity of this reaction may be further shown by the use of kidney polysomes that do not normally synthesize serine dehydratase. When these latter polysomes are isolated, even after the addition of crude and purified serine dehydratase, no reaction with anti-serine dehydratase-Fab fragments could be demonstrated. These results indicate that the reaction of the Fab fragments are specific for polysomes that synthesize rat serum albumin or rat liver serine dehydratase. Furthermore, they demonstrate that even with this high degree of specificity, some polysomes in the fraction labeled \"free\" are in the process of synthesizing rat serum albumin while bound polysomes to a significant, if not major, degree are the site of the synthesis of rat liver serine dehydratase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201708"} {"pmid": "4201709", "title": "Effect of aldosterone on active and passive conductance and ENA in the toad bladder.", "content": "Effect of aldosterone on active and passive conductance and ENA in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201709"} {"pmid": "4201712", "title": "Nitrobenzene reduction and reductive cleavage of azobenzenes in two species of Arachnida.", "content": "Nitrobenzene reduction and reductive cleavage of azobenzenes in two species of Arachnida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201712"} {"pmid": "4201713", "title": "An electron cytochemical study of 6-phosphogluconate dehydrogenase activity in infected erythrocytes during malaria.", "content": "An electron cytochemical study of 6-phosphogluconate dehydrogenase activity in infected erythrocytes during malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201713"} {"pmid": "4201716", "title": "Enzymatic oxidation of linolenic acid in aqueous wheat flour suspensions.", "content": "Enzymatic oxidation of linolenic acid in aqueous wheat flour suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201716"} {"pmid": "4201715", "title": "Analysis of lipoxygenase nonvolatile reaction products of linoleic acid in aqueous cereal suspensions by urea extraction and gas chromatography.", "content": "Analysis of lipoxygenase nonvolatile reaction products of linoleic acid in aqueous cereal suspensions by urea extraction and gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201715"} {"pmid": "4201718", "title": "Symposium on the patient with long-term illness. Foreword.", "content": "Symposium on the patient with long-term illness. Foreword.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201718"} {"pmid": "4201719", "title": "Social isolation and the nursing process.", "content": "Social isolation and the nursing process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201719"} {"pmid": "4201720", "title": "Juvenile diabetes mellitus.", "content": "Juvenile diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201720"} {"pmid": "4201721", "title": "Long-term care of the patient with cancer.", "content": "Long-term care of the patient with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201721"} {"pmid": "4201722", "title": "Human sexuality and nursing practice.", "content": "Human sexuality and nursing practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201722"} {"pmid": "4201735", "title": "Pulpal responses to \"composite\" dental materials lined with Tubulitec or Dropsin.", "content": "Pulpal responses to \"composite\" dental materials lined with Tubulitec or Dropsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201735"} {"pmid": "4201736", "title": "A histopathologic study of replanted teeth with superficially demineralized root surfaces in Java monkeys.", "content": "A histopathologic study of replanted teeth with superficially demineralized root surfaces in Java monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201736"} {"pmid": "4201738", "title": "Jejunal disaccharidases in children with selective IgA deficiency.", "content": "Jejunal disaccharidases in children with selective IgA deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201738"} {"pmid": "4201737", "title": "The immunoglobulin concentrations in serum and bowel secretion in patients with Crohn's disease.", "content": "The immunoglobulin concentrations in serum and bowel secretion in patients with Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201737"} {"pmid": "4201742", "title": "Prevention of Rh-immunization. Modified production of IgG anti-Rh for intravenous application by ion exchange chromatography (IEC).", "content": "Prevention of Rh-immunization. Modified production of IgG anti-Rh for intravenous application by ion exchange chromatography (IEC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201742"} {"pmid": "4201743", "title": "Production of antibodies against hepatitis-associated antigen in donkeys.", "content": "Production of antibodies against hepatitis-associated antigen in donkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201743"} {"pmid": "4201747", "title": "Some aspects of leucocyte behaviour in haemodialysis.", "content": "Some aspects of leucocyte behaviour in haemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201747"} {"pmid": "4201748", "title": "Congenital hypoproconvertinemia (factor VII deficiency). A report of two cases belonging to two different kindreds.", "content": "Congenital hypoproconvertinemia (factor VII deficiency). A report of two cases belonging to two different kindreds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201748"} {"pmid": "4201749", "title": "Platelet defect in a case of Ehlers-Danlos syndrome.", "content": "Platelet defect in a case of Ehlers-Danlos syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201749"} {"pmid": "4201750", "title": "Pyknocytosis in heat-stroke.", "content": "Pyknocytosis in heat-stroke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201750"} {"pmid": "4201751", "title": "Beta-adrenergic blockade in essential hypertension. Effects of propranolol on hemodynamic parameters and plasma renin activity.", "content": "Beta-adrenergic blockade in essential hypertension. Effects of propranolol on hemodynamic parameters and plasma renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201751"} {"pmid": "4201752", "title": "Mixed sodium chloride aerosol and nitrogen dioxide in air: biological effects on monkeys and rats.", "content": "Mixed sodium chloride aerosol and nitrogen dioxide in air: biological effects on monkeys and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201752"} {"pmid": "4201753", "title": "Lymphocytic beta-glucuronidase in the lymphoproliferative syndromes.", "content": "Lymphocytic beta-glucuronidase in the lymphoproliferative syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201753"} {"pmid": "4201754", "title": "The availability of food folate in man.", "content": "The availability of food folate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201754"} {"pmid": "4201755", "title": "Some applications of quantitative whole-body scanning in haematology.", "content": "Some applications of quantitative whole-body scanning in haematology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201755"} {"pmid": "4201756", "title": "Carcinoma of the duodenum: comparison of surgery, radiotherapy, and chemotherapy.", "content": "Carcinoma of the duodenum: comparison of surgery, radiotherapy, and chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201756"} {"pmid": "4201758", "title": "Proceedings: the role of humoral factors and diamine oxidase activity in shock after intestinal ischaemia in rabbits.", "content": "Proceedings: the role of humoral factors and diamine oxidase activity in shock after intestinal ischaemia in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201758"} {"pmid": "4201757", "title": "Proceedings: factors determining marker concentration during continuous blood-volume measurement during haemorrhage and infusion.", "content": "Proceedings: factors determining marker concentration during continuous blood-volume measurement during haemorrhage and infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201757"} {"pmid": "4201759", "title": "Proceedings: implantation of pancreatic islets into the portal vein of diabetic rats.", "content": "Proceedings: implantation of pancreatic islets into the portal vein of diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201759"} {"pmid": "4201760", "title": "Proceedings: the survival of transplanted isolated pancreatic islets in the omentum and testis.", "content": "Proceedings: the survival of transplanted isolated pancreatic islets in the omentum and testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201760"} {"pmid": "4201761", "title": "Proceedings: human and computer-aided diagnosis of lower gastro-intestinal disorders in 468 patients.", "content": "Proceedings: human and computer-aided diagnosis of lower gastro-intestinal disorders in 468 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201761"} {"pmid": "4201762", "title": "The origin, course and termination of vestibulospinal fibers in the toad. An experimental-anatomical study, with comments on other descending supraspinal fiber systems to the spinal cord.", "content": "The origin, course and termination of vestibulospinal fibers in the toad. An experimental-anatomical study, with comments on other descending supraspinal fiber systems to the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201762"} {"pmid": "4201763", "title": "Effects of artificial mothers and visual experience on adrenal responsiveness of infant monkeys.", "content": "Effects of artificial mothers and visual experience on adrenal responsiveness of infant monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201763"} {"pmid": "4201764", "title": "Testosterone-binding globulin in stump-tailed macaque monkeys (Macaca speciosa).", "content": "Testosterone-binding globulin in stump-tailed macaque monkeys (Macaca speciosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201764"} {"pmid": "4201765", "title": "Acute and chronic oral toxicity of chlorinated dibenzofurans to salmonid fishes.", "content": "Acute and chronic oral toxicity of chlorinated dibenzofurans to salmonid fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201765"} {"pmid": "4201766", "title": "The search for chlorinated dibenzofurans and chlorinated dibenzodioxins in wildlife populations showing elevated levels of embryonic death.", "content": "The search for chlorinated dibenzofurans and chlorinated dibenzodioxins in wildlife populations showing elevated levels of embryonic death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201766"} {"pmid": "4201767", "title": "Biological responses of the nonhuman primate, chicken, and rat to chlorinated dibenzo-p-dioxin ingestion.", "content": "Biological responses of the nonhuman primate, chicken, and rat to chlorinated dibenzo-p-dioxin ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201767"} {"pmid": "4201768", "title": "Etiology of chick edema disease.", "content": "Etiology of chick edema disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201768"} {"pmid": "4201769", "title": "Electron microscopic localization of occluding junctions in the primate ciliary process and pars plana.", "content": "Electron microscopic localization of occluding junctions in the primate ciliary process and pars plana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201769"} {"pmid": "4201770", "title": "Changes in corticosteroid usage by chronic asthma patients during a year of cromoglycate treatment.", "content": "Changes in corticosteroid usage by chronic asthma patients during a year of cromoglycate treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201770"} {"pmid": "4201772", "title": "Immersion refractometry of isolated bacterial cell walls.", "content": "Immersion refractometry of isolated bacterial cell walls. Immersion-refractometric and light-scattering measurements were adapted to determinations of average refractive indices and physical compactness of isolated bacterial cell walls. The structures were immersed in solutions containing various concentrations of polymer molecules that cannot penetrate into wall pores, and then an estimate was made of the polymer concentration or the refractive index of the polymer solution in which light scattering was reduced to zero. Because each wall preparation was heterogeneous, the refractive index of the medium for zero light scattering had to be estimated by extrapolation. Refractive indices for walls suspended in bovine serum albumin solutions ranged from 1.348 for walls of the rod form of Arthrobacter crystallopoietes to 1.382 for walls of the teichoic acid deficient, 52A5 strain of Staphylococcus aureus. These indices were used to calculate approximate values for solids content per milliliter, and the calculated values agreed closely with those estimated from a knowledge of dextran-impermeable volumes per gram, dry weight, of the walls. When large molecules such as dextrans or serum albumin were used for immersion refractometry, the refractive indices obtained were for entire walls, including both wall polymers and wall water. When smaller molecules that can penetrate wall pores to various extents were used with Micrococcus lysodeikticus walls, the average, apparent refractive index of the structures increased as the molecular size of probing molecules was decreased. It was possible to obtain an estimate of 1.45 to 1.46 for the refractive index of wall polymers, predominantly peptidoglycans in this case, by extrapolating the curve for refractive index versus molecular radius to a value of 0.2 nm, the approximate radius of a water molecule. This relatively low value for polymer refractive index was interpreted as evidence in favor of the amorphous, elastic model of peptidoglycan structure and against the crystalline, rigid model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201772"} {"pmid": "4201771", "title": "Role of methionine in biosynthesis of prodigiosin by Serratia marcescens.", "content": "Role of methionine in biosynthesis of prodigiosin by Serratia marcescens. Methionine alone did not allow biosynthesis of prodigiosin (2-methyl-3-amyl-6-methoxyprodigiosene) in nonproliferating cells (NPC) of Serratia marcescens strain Nima. However, when methionine was added to NPC synthesizing prodigiosin in the presence of other amino acids, the lag period for synthesis of prodigiosin was shortened, an increased amount of the pigment was formed, and the optimal concentrations of the other amino acids were reduced. Less prodigiosin was synthesized when addition of methionine was delayed beyond 4 h. The specific activity of prodigiosin synthesized by addition of (14)CH(3)-methionine was 40 to 50 times greater than that synthesized from methionine-2-(14)C or (14)COOH-methionine. NPC of mutant OF of S. marcescens synthesized norprodigiosin (2-methyl-3-amyl-6-hydroxyprodigiosene), and the specific activity of this pigment synthesized in the presence of (14)CH(3)-methionine was only 5 to 13 times greater than that synthesized from methionine-2-(14)C or (14)COOH-methionine. A particulate, cell-free extract of mutant WF of S. marcescens methylated norprodigiosin to form prodigiosin. When the extract was added to NPC of mutant OF synthesizing norprodigiosin in the presence of (14)CH(3)-methionine, the prodigiosin formed had 80% greater specific activity than the norprodigiosin synthesized in the absence of the extract. The C6 hydroxyl group of norprodigiosin was methylated in the presence of the extract and methionine. Biosynthesis of prodigiosin by NPC of strain Nima also was augmented by addition of S-adenosylmethionine. Various analogues of methionine such as norleucine, norvaline, ethionine, and alpha-methylmethionine did not affect biosynthesis of prodigiosin by NPC either in the presence or absence of methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201771"} {"pmid": "4201773", "title": "Sites of cellular autolysis in Lactobacillus acidophilus.", "content": "Sites of cellular autolysis in Lactobacillus acidophilus. Ultrastructural changes which occur during cellular autolysis of Lactobacillus acidophilus strain 63AM Gasser in 0.05 M citrate buffer, pH 5.0, were examined. Early in the process, randomly distributed electron-dense patches were seen on the wall surface, along with an accompanying eversion of mesosomes. Later, after a loss of about 20% of the initial cellular turbidity, dissolution from the outside of nascent cross walls was seen. This observation was related to the normal process of cell separation. After this stage, short lengths of the cylindrical portion of the wall appeared to be completely removed in a random manner over the entire surface. This dissolution produced gaps in the wall which allowed the extrusion of membrane and cytoplasm. Although membrane was usually extruded through one major, polar, subpolar, or septal site, other secondary points of membrane extrusion were also frequently seen in the same cell section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201773"} {"pmid": "4201774", "title": "Isolation of the bacteriophage lambda receptor from Escherichia coli.", "content": "Isolation of the bacteriophage lambda receptor from Escherichia coli. A factor which inactivates the phage lambda can be extracted from Escherichia coli. This factor is a protein and is located in the outer membrane of the bacterial envelope. It is found in extracts of strains which are sensitive to phage lambda, but not in extracts of strains specifically resistant to this phage. We conclude that this factor is the lambda receptor, responsible for the specific adsorption of the phage lambda to E. coli cells. A partial purification of the lambda receptor is described. Inactivation of the phage by purified receptor is shown to be accompanied by the release of deoxyribonucleic acid from the phage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201774"} {"pmid": "4201775", "title": "New procedure for the isolation of membrane vesicles of Bacillus subtilis and an electron microscopy study of their ultrastructure.", "content": "New procedure for the isolation of membrane vesicles of Bacillus subtilis and an electron microscopy study of their ultrastructure. A rapid procedure for the isolation of membrane vesicles of Bacillus subtilis is described that minimizes the action of proteolytic enzymes, excreted by this organism, on the membrane proteins. The membrane vesicles obtained have, in addition to a low endogenous respiration rate, a low endogenous activity for transport of amino acids and carboxylic acids. In the presence of the electron donor, ascorbate-phenazine methosulfate, the transport activities for these compounds were comparable to the activities of intact cells. In addition, these activities were retained for a prolonged period of time. Electron microscopy examination of thin sections of the vesicles showed that the preparation consisted almost exclusively of membrane vesicles which were not contaminated with other cell components. The membrane vesicles, which are six to seven times smaller in diameter than protoplasts, often enclosed smaller vesicles. Freeze-etching of intact cells, protoplasts, and membrane vesicles showed that the orientation of the membrane of the vesicles was identical to the orientation of the plasma membrane in intact cells and protoplasts. This also held for the majority of the membranes of the enclosed vesicles, only 15% having the opposite orientation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201775"} {"pmid": "4201777", "title": "Kinetic studies of citrate synthase from rat kidney and rat brain.", "content": "Kinetic studies of citrate synthase from rat kidney and rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201777"} {"pmid": "4201776", "title": "Developmental block in citric acid cycle mutants of Bacillus subtilis.", "content": "Developmental block in citric acid cycle mutants of Bacillus subtilis. Mutants deficient in different enzymes of the citric acid cycle can be subdivided into two groups according to the frequency at which they produce heat-resistant spores in nutrient sporulation medium. However, the majority of cells can develop in this medium only to the axial filament stage I of sporulation; aconitase and isocitrate dehydrogenase mutants need the addition of glutamate to reach this stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201776"} {"pmid": "4201778", "title": "Multiple genes for lysozyme in birds. Studies on black swan egg white lysozymes.", "content": "Multiple genes for lysozyme in birds. Studies on black swan egg white lysozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201778"} {"pmid": "4201779", "title": "Structural organization of three pools of acetyl coenzyme A in Tetrahymena.", "content": "Structural organization of three pools of acetyl coenzyme A in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201779"} {"pmid": "4201781", "title": "Effect of adenosine monophosphate on intermediate metabolism and ribonucleic acid synthesis in Tetrahymena.", "content": "Effect of adenosine monophosphate on intermediate metabolism and ribonucleic acid synthesis in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201781"} {"pmid": "4201780", "title": "Effect of tolbutamide on the intracellular flow of acetyl coenzyme A in Tetrahymena.", "content": "Effect of tolbutamide on the intracellular flow of acetyl coenzyme A in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201780"} {"pmid": "4201782", "title": "Studies on a nuclease from Ustilago maydis. I. Purification, properties, and implication in recombination of the enzyme.", "content": "Studies on a nuclease from Ustilago maydis. I. Purification, properties, and implication in recombination of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201782"} {"pmid": "4201783", "title": "Ionization behavior of the histidine residue in the catalytic triad of serine proteases. Mechanistic implications.", "content": "Ionization behavior of the histidine residue in the catalytic triad of serine proteases. Mechanistic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201783"} {"pmid": "4201785", "title": "Serum heat stable alkaline phosphatase levels in normal and abnormal pregnancies.", "content": "Serum heat stable alkaline phosphatase levels in normal and abnormal pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201785"} {"pmid": "4201784", "title": "Response of rats to amino acid supplementation of brown egg albumin.", "content": "Response of rats to amino acid supplementation of brown egg albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201784"} {"pmid": "4201786", "title": "Amino acid utilization during total parenteral nutrition in the surgical neonate.", "content": "Amino acid utilization during total parenteral nutrition in the surgical neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201786"} {"pmid": "4201787", "title": "The long-term total intravenous feeding of infants using peripheral veins.", "content": "The long-term total intravenous feeding of infants using peripheral veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201787"} {"pmid": "4201788", "title": "Structural organization of the pars plana-ora serrata transition in the human and monkey eye with emphasis on protein barriers.", "content": "Structural organization of the pars plana-ora serrata transition in the human and monkey eye with emphasis on protein barriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201788"} {"pmid": "4201789", "title": "Circulating tissue antigens. II. Studies on an organ-specific antigen of human liver.", "content": "Circulating tissue antigens. II. Studies on an organ-specific antigen of human liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201789"} {"pmid": "4201790", "title": "Solubilized myocardial adenylate cyclase: activation by prostaglandins.", "content": "Solubilized myocardial adenylate cyclase: activation by prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201790"} {"pmid": "4201791", "title": "Letter: Neurotoxic effects of glutamate.", "content": "Letter: Neurotoxic effects of glutamate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201791"} {"pmid": "4201793", "title": "Neurofibromatosis, renal artery aneurysms and hypertension: case report.", "content": "Neurofibromatosis, renal artery aneurysms and hypertension: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201793"} {"pmid": "4201792", "title": "Letter: Stimulant drugs for problem children.", "content": "Letter: Stimulant drugs for problem children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201792"} {"pmid": "4201794", "title": "Anterior urethral valves.", "content": "Anterior urethral valves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201794"} {"pmid": "4201796", "title": "Determination of trace quantities of anticholinesterase pesticides.", "content": "Determination of trace quantities of anticholinesterase pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201796"} {"pmid": "4201795", "title": "Streptococcal epidemic in an aircraft carrier.", "content": "Streptococcal epidemic in an aircraft carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201795"} {"pmid": "4201797", "title": "Carbonic anhydrase: a new method of detection on polyacrylamide gels using conductivity measurements.", "content": "Carbonic anhydrase: a new method of detection on polyacrylamide gels using conductivity measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201797"} {"pmid": "4201807", "title": "Lipid-protein interactions of erythrocyte membranes: comparison of normal O, Rh (D) positive with the rare O, Rh null.", "content": "Lipid-protein interactions of erythrocyte membranes: comparison of normal O, Rh (D) positive with the rare O, Rh null.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201807"} {"pmid": "4201808", "title": "Mucopolysaccharidosis 3 A (Sanfilippo A disease): deficiency of a heparin sulfamidase in skin fibroblasts and leucocytes.", "content": "Mucopolysaccharidosis 3 A (Sanfilippo A disease): deficiency of a heparin sulfamidase in skin fibroblasts and leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201808"} {"pmid": "4201809", "title": "Study on the existence of TRH in the cerebrospinal fluid in humans.", "content": "Study on the existence of TRH in the cerebrospinal fluid in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201809"} {"pmid": "4201810", "title": "Gel electrophoresis of partially purified cytochromes P450 from liver microsomes of variously-treated rats.", "content": "Gel electrophoresis of partially purified cytochromes P450 from liver microsomes of variously-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201810"} {"pmid": "4201811", "title": "Comparison of techniques for quantifying serum alpha1-antitrypsin.", "content": "Comparison of techniques for quantifying serum alpha1-antitrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201811"} {"pmid": "4201812", "title": "A tanned cell haemagglutination test for the detection of hepatitis-associated-antigen (Au-Ag) and antibody (anti-Au).", "content": "A tanned cell haemagglutination test for the detection of hepatitis-associated-antigen (Au-Ag) and antibody (anti-Au).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201812"} {"pmid": "4201813", "title": "Voltammetric identification of organochlorine insecticides, polychlorinated biphenyls, polychlorinated naphthalenes and polychlorinated benzenes.", "content": "Voltammetric identification of organochlorine insecticides, polychlorinated biphenyls, polychlorinated naphthalenes and polychlorinated benzenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201813"} {"pmid": "4201814", "title": "Experiments on Rouleu formation.", "content": "Experiments on Rouleu formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201814"} {"pmid": "4201815", "title": "Dose-related effects of isoprenaline on the distribution of cardiac output and myocardial blood flow in conscious monkeys.", "content": "Dose-related effects of isoprenaline on the distribution of cardiac output and myocardial blood flow in conscious monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201815"} {"pmid": "4201816", "title": "Experience with the use of computer simulation models in medical education.", "content": "Experience with the use of computer simulation models in medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201816"} {"pmid": "4201817", "title": "The treatment of asthma.", "content": "The treatment of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201817"} {"pmid": "4201818", "title": "Immunochemical analysis of tissue antigens in different corneal layers and sclera.", "content": "Immunochemical analysis of tissue antigens in different corneal layers and sclera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201818"} {"pmid": "4201819", "title": "Effect of different complex nutrients on neomycin production by Streptomyces fradiae H.", "content": "Effect of different complex nutrients on neomycin production by Streptomyces fradiae H.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201819"} {"pmid": "4201820", "title": "Competition between inoculum strains of Rhizobium japonicum in the process of soybean nodulation during three planting periods.", "content": "Competition between inoculum strains of Rhizobium japonicum in the process of soybean nodulation during three planting periods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201820"} {"pmid": "4201821", "title": "Distribution of ABO and rhesus blood groups in patients with gastric carcinoma, with reference to its site of origin.", "content": "Distribution of ABO and rhesus blood groups in patients with gastric carcinoma, with reference to its site of origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201821"} {"pmid": "4201822", "title": "Tuberculous enteritis. A report of three patients.", "content": "Tuberculous enteritis. A report of three patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201822"} {"pmid": "4201824", "title": "Transmission of IgA to the rabbit foetus and the suckling rat.", "content": "Transmission of IgA to the rabbit foetus and the suckling rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201824"} {"pmid": "4201827", "title": "Studies on the mode of action of glutaraldehyde on Escherichia coli.", "content": "Studies on the mode of action of glutaraldehyde on Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201827"} {"pmid": "4201828", "title": "Germination of spores of Bacillus cereus in milk and milk dialysates: effect of heat treatment.", "content": "Germination of spores of Bacillus cereus in milk and milk dialysates: effect of heat treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201828"} {"pmid": "4201825", "title": "Cross-reactive human blood group H-active polysaccharide from Helix pomatia. I. Detection with catfish anti-H and eel sera.", "content": "Cross-reactive human blood group H-active polysaccharide from Helix pomatia. I. Detection with catfish anti-H and eel sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201825"} {"pmid": "4201826", "title": "Border disease-like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses.", "content": "Border disease-like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201826"} {"pmid": "4201829", "title": "A quantitative comparison of the faecal microflora of baboons fed a natural diet or a synthetic diet complete or deficient in pyridoxine or riboflavin.", "content": "A quantitative comparison of the faecal microflora of baboons fed a natural diet or a synthetic diet complete or deficient in pyridoxine or riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201829"} {"pmid": "4201830", "title": "Increased serum thyroxine levels in euthyroid narcotic addicts.", "content": "Increased serum thyroxine levels in euthyroid narcotic addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201830"} {"pmid": "4201831", "title": "Abnormalities of hypothalamo-hypophyseal-thyroid axis in patients with Graves' ophthalmopathy.", "content": "Abnormalities of hypothalamo-hypophyseal-thyroid axis in patients with Graves' ophthalmopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201831"} {"pmid": "4201832", "title": "A simple precipitin test for corticosteroid-binding globulin: use in a search for the absence of corticosteroid-binding globulin in 10,000 subjects.", "content": "A simple precipitin test for corticosteroid-binding globulin: use in a search for the absence of corticosteroid-binding globulin in 10,000 subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201832"} {"pmid": "4201833", "title": "Ferritin-tagged antibody cross-reactions among rinderpest, canine distemper, and measles viruses.", "content": "Ferritin-tagged antibody cross-reactions among rinderpest, canine distemper, and measles viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201833"} {"pmid": "4201834", "title": "The production of interferon by chemostat cultures of mouse LS-cells grown in chemically-defined, protein-free medium.", "content": "The production of interferon by chemostat cultures of mouse LS-cells grown in chemically-defined, protein-free medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201834"} {"pmid": "4201835", "title": "Characterization of three phages lytic for Brucella species.", "content": "Characterization of three phages lytic for Brucella species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201835"} {"pmid": "4201836", "title": "The growth of two togaviruses in cultured mosquito and vertebrate cells.", "content": "The growth of two togaviruses in cultured mosquito and vertebrate cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201836"} {"pmid": "4201837", "title": "The length of the filamentous Pseudomonas aeruginosa bacteriophage Pf.", "content": "The length of the filamentous Pseudomonas aeruginosa bacteriophage Pf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201837"} {"pmid": "4201839", "title": "The significance of plasma proteins in urinary casts.", "content": "The significance of plasma proteins in urinary casts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201839"} {"pmid": "4201840", "title": "The effects of agents that modify muscarinic tone upon behavior controlled by an avoidance schedule that employs signaled unavoidable shock.", "content": "The effects of agents that modify muscarinic tone upon behavior controlled by an avoidance schedule that employs signaled unavoidable shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201840"} {"pmid": "4201844", "title": "Standardized horse antihuman lymphocyte globulin for clinical use.", "content": "Standardized horse antihuman lymphocyte globulin for clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201844"} {"pmid": "4201848", "title": "Mechanisms of motor control of two types of tracking movements in monkeys.", "content": "Mechanisms of motor control of two types of tracking movements in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201848"} {"pmid": "4201851", "title": "Electron microscope study of the endothelium of stored and cryopreserved monkey corneas.", "content": "Electron microscope study of the endothelium of stored and cryopreserved monkey corneas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201851"} {"pmid": "4201852", "title": "Pseudomonas aeruginosa endocarditis. Report of a case, with review of the literature.", "content": "Pseudomonas aeruginosa endocarditis. Report of a case, with review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201852"} {"pmid": "4201855", "title": "Esterase-2 in Ephestia kühniella. I. Genetics and characterization.", "content": "Esterase-2 in Ephestia kühniella. I. Genetics and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201855"} {"pmid": "4201856", "title": "Diversity of RNA sequences in Drosophila melanogaster.", "content": "Diversity of RNA sequences in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201856"} {"pmid": "4201857", "title": "Search for nonallelic structural genes for gamma-chains of fetal hemoglobin in some primates.", "content": "Search for nonallelic structural genes for gamma-chains of fetal hemoglobin in some primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201857"} {"pmid": "4201858", "title": "On the relationship between the urea-soluble and citric acid-soluble proteins of bovine snout epidermis.", "content": "On the relationship between the urea-soluble and citric acid-soluble proteins of bovine snout epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201858"} {"pmid": "4201859", "title": "Some observations on future trends in nuclear diagnostic instrumentation.", "content": "Some observations on future trends in nuclear diagnostic instrumentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201859"} {"pmid": "4201860", "title": "The past seventy-five years in radiotherapy.", "content": "The past seventy-five years in radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201860"} {"pmid": "4201862", "title": "Pyruvate kinase from Hydrogenomonas H 16.", "content": "Pyruvate kinase from Hydrogenomonas H 16.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201862"} {"pmid": "4201863", "title": "An enzyme from Bacillus subtilis B with exo-beta-N-acetylmuramidase activity.", "content": "An enzyme from Bacillus subtilis B with exo-beta-N-acetylmuramidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201863"} {"pmid": "4201864", "title": "Invertebrate animals--what can they contribute to cancer research?", "content": "Invertebrate animals--what can they contribute to cancer research?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201864"} {"pmid": "4201865", "title": "Delayed cellular immunity response as measured by tuberculin testing of an elderly population.", "content": "Delayed cellular immunity response as measured by tuberculin testing of an elderly population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201865"} {"pmid": "4201866", "title": "Blood groups and hypertension.", "content": "Blood groups and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201866"} {"pmid": "4201867", "title": "Cerebrovascular response to intracarotid injection of serotonin before and after middle cerebral artery occlusion.", "content": "Cerebrovascular response to intracarotid injection of serotonin before and after middle cerebral artery occlusion. The effect of intracarotid injection of serotonin (5-HT) on internal carotid artery flow and oxygen availability (O(2)a) of the cerebral cortex was studied in 10 baboons. Vasoconstriction occurred in the vascular bed of the territory supplied by the injected artery. After one middle cerebral artery was occluded the vasoconstrictor effect of 5-HT was more pronounced, particularly in the non-ischaemic hemisphere. The capacity of the cerebral vessels to provide collateral blood flow was reduced in both ischaemic and non-ischaemic areas of brain. As a result of focal cerebral ischaemia, 5-HT may accumulate in the brain and contribute to the progression of infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201867"} {"pmid": "4201868", "title": "Effect of carotid ligation on cerebral blood flow in baboons. I. Response to altered arterial PCO2.", "content": "Effect of carotid ligation on cerebral blood flow in baboons. I. Response to altered arterial PCO2. Measurements of cerebral blood flow (CBF) were made in anaesthetized baboons before and after ipsilateral carotid artery ligation and also after bilateral carotid ligation. Results showed that at normocapnia (PaCO(2) 38-39 mmHg) there was little change in cerebral blood flow on ipsilateral carotid ligation, but when both carotid arteries were tied the blood flow to the brain fell significantly. At hypercapnia (PaCO(2) 58-60 mmHg) the CBF/CO(2) gradient fell significantly on ipsilateral carotid ligation; on bilateral carotid ligation there was only minimal rise in cerebral blood flow in response to the rise in PaCO(2). At hypocapnia (PaCO(2) 20-21 mmHg) the gradients of fall in the CBF were similar before and after ipsilateral carotid ligation; after bilateral carotid ligation there was minimal change in the CBF in response to the fall in the PaCO(2). It is suggested that, although cerebral blood flow may be normal after ipsilateral carotid ligation, the circulatory reserve of the brain is not sufficient to meet physiological challenges. This may be the reason for the development of delayed neurological complications after carotid artery ligation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201868"} {"pmid": "4201871", "title": "Inactivation of transforming DNA by ultraviolet light. I. Near-UV action spectrum for marker inactivation.", "content": "Inactivation of transforming DNA by ultraviolet light. I. Near-UV action spectrum for marker inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201871"} {"pmid": "4201872", "title": "Inactivation of transforming DNA by ultraviolet light. II. Protection by histidine against near-UV irradiation: action spectrum.", "content": "Inactivation of transforming DNA by ultraviolet light. II. Protection by histidine against near-UV irradiation: action spectrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201872"} {"pmid": "4201873", "title": "Inactivation of transforming DNA by ultraviolet light. 3. Further observations on the effects of 365 nm radiation.", "content": "Inactivation of transforming DNA by ultraviolet light. 3. Further observations on the effects of 365 nm radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201873"} {"pmid": "4201874", "title": "Repair of ultraviolet-induced DNA damage in the subcellular systems of Bacillus subtilis.", "content": "Repair of ultraviolet-induced DNA damage in the subcellular systems of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201874"} {"pmid": "4201876", "title": "Influence of disodium etidronate on clinical and laboratory manifestations of Paget's disease of bone (osteitis deformans).", "content": "Influence of disodium etidronate on clinical and laboratory manifestations of Paget's disease of bone (osteitis deformans).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201876"} {"pmid": "4201877", "title": "Editorial: Diphosphonate treatment in bone disease.", "content": "Editorial: Diphosphonate treatment in bone disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201877"} {"pmid": "4201880", "title": "Different effects of bursectomy of chickens on immune response to Newcastle disease virus and Salmonella pullorum antigens.", "content": "Different effects of bursectomy of chickens on immune response to Newcastle disease virus and Salmonella pullorum antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201880"} {"pmid": "4201879", "title": "Toxicity resulting from feeding experimentally molded corn to broiler chicks.", "content": "Toxicity resulting from feeding experimentally molded corn to broiler chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201879"} {"pmid": "4201881", "title": "The effect of external shell treatments on salmonella penetration of chicken eggs.", "content": "The effect of external shell treatments on salmonella penetration of chicken eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201881"} {"pmid": "4201882", "title": "Epidemiology of Marek's disease (MD): studies on the incidence of MD precipitins in some zoo birds.", "content": "Epidemiology of Marek's disease (MD): studies on the incidence of MD precipitins in some zoo birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201882"} {"pmid": "4201887", "title": "Respiratory rate and succinic dehydrogenase activity in the egg of Ciona intestinalis (ascidian) upon fertilization.", "content": "Respiratory rate and succinic dehydrogenase activity in the egg of Ciona intestinalis (ascidian) upon fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201887"} {"pmid": "4201890", "title": "Bone formation and calcification in gastric cancer--case report and review of literature.", "content": "Bone formation and calcification in gastric cancer--case report and review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201890"} {"pmid": "4201875", "title": "The parasexual cycle in Aspergillus flavus.", "content": "The parasexual cycle in Aspergillus flavus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201875"} {"pmid": "4201892", "title": "Monoamine oxidases: versatility of catalytic properties and possible biological functions.", "content": "Monoamine oxidases: versatility of catalytic properties and possible biological functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201892"} {"pmid": "4201891", "title": "Semisynthetic penicillins.", "content": "Semisynthetic penicillins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201891"} {"pmid": "4201893", "title": "Drug metabolism in canine duodenum.", "content": "Drug metabolism in canine duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201893"} {"pmid": "4201895", "title": "Chemical structure and biochemical activity of cord factor analogs. 2. Relationships between activity and stereochemistry of the sugar moiety.", "content": "Chemical structure and biochemical activity of cord factor analogs. 2. Relationships between activity and stereochemistry of the sugar moiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201895"} {"pmid": "4201894", "title": "Interference of influenza-specific IgA antibodies present in throat washings with isolation of the virus.", "content": "Interference of influenza-specific IgA antibodies present in throat washings with isolation of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201894"} {"pmid": "4201886", "title": "Discontinuous ficoll gradient separation of normal and malignant cells: cytologic applicability. I.", "content": "Discontinuous ficoll gradient separation of normal and malignant cells: cytologic applicability. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201886"} {"pmid": "4201898", "title": "Structure and configuration of the polyprenoid side chain of dihydromenaquinones from Myco- and Corynebacteria.", "content": "Structure and configuration of the polyprenoid side chain of dihydromenaquinones from Myco- and Corynebacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201898"} {"pmid": "4201899", "title": "Roentgenographic evaluation in total hip replacement. A study of 100 McKee-Farrar prosthetic replacements.", "content": "Roentgenographic evaluation in total hip replacement. A study of 100 McKee-Farrar prosthetic replacements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201899"} {"pmid": "4201900", "title": "Results of total hip replacement. A clinical follow-up study.", "content": "Results of total hip replacement. A clinical follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201900"} {"pmid": "4201901", "title": "Clinical follow-up of total hip replacement.", "content": "Clinical follow-up of total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201901"} {"pmid": "4201902", "title": "A comparative review of the McKee-Farrar and Charnley total hip prostheses.", "content": "A comparative review of the McKee-Farrar and Charnley total hip prostheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201902"} {"pmid": "4201904", "title": "The statistics of the McKee-Farrar method of total hip replacement.", "content": "The statistics of the McKee-Farrar method of total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201904"} {"pmid": "4201903", "title": "Three years of experience with total hip replacement.", "content": "Three years of experience with total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201903"} {"pmid": "4201906", "title": "Complications after total hip arthroplasty according to Charnley in a Swedish series of cases.", "content": "Complications after total hip arthroplasty according to Charnley in a Swedish series of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201906"} {"pmid": "4201905", "title": "Some complications of total hip replacement.", "content": "Some complications of total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201905"} {"pmid": "4201907", "title": "A comparison of anubis baboons, hamadryas baboons and their hybrids at a species border in Ethiopia.", "content": "A comparison of anubis baboons, hamadryas baboons and their hybrids at a species border in Ethiopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201907"} {"pmid": "4201908", "title": "Adult male replacement in one-male troops of purple-faced langurs (Presbytis senex senex) and its effect on population structure.", "content": "Adult male replacement in one-male troops of purple-faced langurs (Presbytis senex senex) and its effect on population structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201908"} {"pmid": "4201909", "title": "Contribution to the ecology of Colobus polykomos satanas (Waterhouse, 1838) of Rio Muni, Republic of Equatorial Guinea.", "content": "Contribution to the ecology of Colobus polykomos satanas (Waterhouse, 1838) of Rio Muni, Republic of Equatorial Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201909"} {"pmid": "4201910", "title": "Cyclic changes in cervical mucus and LH levels in the bonnet macaque (Macaca radiata).", "content": "Cyclic changes in cervical mucus and LH levels in the bonnet macaque (Macaca radiata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201910"} {"pmid": "4201911", "title": "Ovarian steroid patterns in peripheral plasma during the menstrual cycle in the rhesus monkey.", "content": "Ovarian steroid patterns in peripheral plasma during the menstrual cycle in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201911"} {"pmid": "4201912", "title": "Persimmon bezoar in an epiphrenic esophageal diverticulum with endoscopic removal.", "content": "Persimmon bezoar in an epiphrenic esophageal diverticulum with endoscopic removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201912"} {"pmid": "4201914", "title": "Threshold 60-Hz current required for ventricular fibrillation in subjects of various body weights.", "content": "Threshold 60-Hz current required for ventricular fibrillation in subjects of various body weights.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201914"} {"pmid": "4201915", "title": "Preparation HOE 105 (citenazone) in chemoprophylaxis of variola in monkeys: a preliminary communication.", "content": "Preparation HOE 105 (citenazone) in chemoprophylaxis of variola in monkeys: a preliminary communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201915"} {"pmid": "4201917", "title": "Follow-up studies in oral lichen planus.", "content": "Follow-up studies in oral lichen planus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201917"} {"pmid": "4201916", "title": "Screening of drugs for genetic effects.", "content": "Screening of drugs for genetic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201916"} {"pmid": "4201918", "title": "Morphologic changes in lymph node deposits of oral squamous carcinoma.", "content": "Morphologic changes in lymph node deposits of oral squamous carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201918"} {"pmid": "4201919", "title": "Healing of gingival mucoperiosteal flaps after marginal incision in apicoectomy procedures.", "content": "Healing of gingival mucoperiosteal flaps after marginal incision in apicoectomy procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201919"} {"pmid": "4201920", "title": "Mucoepidermoid carcinoma in a lymph node of the parotid sheath simulating condylar tumor.", "content": "Mucoepidermoid carcinoma in a lymph node of the parotid sheath simulating condylar tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201920"} {"pmid": "4201921", "title": "An atypical mandibular tumor caused by Mycobacterium balnei.", "content": "An atypical mandibular tumor caused by Mycobacterium balnei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201921"} {"pmid": "4201923", "title": "Deoxyribonucleic acid repair replication in Pseudomonas aeruginosa after sublethal doses of silver sulfadiazine.", "content": "Deoxyribonucleic acid repair replication in Pseudomonas aeruginosa after sublethal doses of silver sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201923"} {"pmid": "4201931", "title": "Malnutrition studies in Macaca mulatta. 3. Effect on cerebral lipids.", "content": "Malnutrition studies in Macaca mulatta. 3. Effect on cerebral lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201931"} {"pmid": "4201922", "title": "A simple method of estimating renal clearance by renography.", "content": "A simple method of estimating renal clearance by renography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201922"} {"pmid": "4201935", "title": "Lymphocyte transformation and serum agar gel diffusion of rabbits immunized against Neisseria gonorrhoeae and Neisseria catarrhalis.", "content": "Lymphocyte transformation and serum agar gel diffusion of rabbits immunized against Neisseria gonorrhoeae and Neisseria catarrhalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201935"} {"pmid": "4201936", "title": "Induction and reversion of the L-form of Neisseria gonorrhoeae.", "content": "Induction and reversion of the L-form of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201936"} {"pmid": "4201938", "title": "Some enzymological properties of a hatching enzyme (chorionase) isolated from the fresh-water teleost, Oryzias latipes.", "content": "Some enzymological properties of a hatching enzyme (chorionase) isolated from the fresh-water teleost, Oryzias latipes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201938"} {"pmid": "4201937", "title": "Immunochemical studies of adenosine deaminases from several vertebrates and a mollusc.", "content": "Immunochemical studies of adenosine deaminases from several vertebrates and a mollusc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201937"} {"pmid": "4201939", "title": "Isoelectric spectra of different classes of anti-erythrocyte antibodies.", "content": "Isoelectric spectra of different classes of anti-erythrocyte antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201939"} {"pmid": "4201940", "title": "Angina pectoris: diagnosis, evaluation and therapy.", "content": "Angina pectoris: diagnosis, evaluation and therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201940"} {"pmid": "4201942", "title": "Rapid quantitation of the immunopreciptin reaction in agarose gel by electroimmunodiffusion with paper discs.", "content": "Rapid quantitation of the immunopreciptin reaction in agarose gel by electroimmunodiffusion with paper discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201942"} {"pmid": "4201941", "title": "A simple method for the simultaneous detection of human immunoglobulins of both light chain types.", "content": "A simple method for the simultaneous detection of human immunoglobulins of both light chain types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201941"} {"pmid": "4201947", "title": "The bithorax complex--a model for cell determination in Drosophila.", "content": "The bithorax complex--a model for cell determination in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201947"} {"pmid": "4201946", "title": "Accumulation of histidine, 3-methylhistidine, and homocarnosine in the brains of protein-calorie deficient monkeys.", "content": "Accumulation of histidine, 3-methylhistidine, and homocarnosine in the brains of protein-calorie deficient monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201946"} {"pmid": "4201949", "title": "Morphology and life history of Mitraspora cyprini Fujita, parasitic in the kidney of goldfish.", "content": "Morphology and life history of Mitraspora cyprini Fujita, parasitic in the kidney of goldfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201949"} {"pmid": "4201948", "title": "Pseudomonas aeruginosa infections in rats fed on monosodium glutamate with observations on the Pseudomonas flora in their intestines.", "content": "Pseudomonas aeruginosa infections in rats fed on monosodium glutamate with observations on the Pseudomonas flora in their intestines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201948"} {"pmid": "4201950", "title": "Penicillin resistance of gonococci in South Vietnam.", "content": "Penicillin resistance of gonococci in South Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201950"} {"pmid": "4201951", "title": "The diagnosis of farmer's lung.", "content": "The diagnosis of farmer's lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201951"} {"pmid": "4201953", "title": "The effect of dextran-40 on capillary blood flow and capillary diffusion capacity in the anterior tibial muscle of subjects with intermittent claudication.", "content": "The effect of dextran-40 on capillary blood flow and capillary diffusion capacity in the anterior tibial muscle of subjects with intermittent claudication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201953"} {"pmid": "4201952", "title": "Paradox of the immune response to uncomplicated gonococcal urethritis.", "content": "Paradox of the immune response to uncomplicated gonococcal urethritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201952"} {"pmid": "4201954", "title": "A sensitive assay for the determination of dopamine in plasma.", "content": "A sensitive assay for the determination of dopamine in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201954"} {"pmid": "4201956", "title": "The use of ficoll in the preparation of viable islets of langerhans from the rat pancreas.", "content": "The use of ficoll in the preparation of viable islets of langerhans from the rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201956"} {"pmid": "4201957", "title": "The growth of mixed population of Lactobacillus casei and nisin producing strain of Streptococcus lactis in batch and continuous cultures.", "content": "The growth of mixed population of Lactobacillus casei and nisin producing strain of Streptococcus lactis in batch and continuous cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201957"} {"pmid": "4201958", "title": "Behaviour of aflatoxins in some meat products.", "content": "Behaviour of aflatoxins in some meat products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201958"} {"pmid": "4201959", "title": "Calcification and ossification in epulides in man (excluding giant cell epulides).", "content": "Calcification and ossification in epulides in man (excluding giant cell epulides).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201959"} {"pmid": "4201960", "title": "The latex agglutination test for the study of the M protein of group A streptococci and of the corresponding antibodies.", "content": "The latex agglutination test for the study of the M protein of group A streptococci and of the corresponding antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201960"} {"pmid": "4201962", "title": "Hyperalimentation-a review.", "content": "Hyperalimentation-a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201962"} {"pmid": "4201963", "title": "New jejunostomy feed.", "content": "New jejunostomy feed. Three patients with duodenal fistulae were fed solely with an easily prepared, inexpensive jejunostomy feed for 14, 21, and 23 days respectively. Sodium, potassium, and nitrogen balances became positive, diarrhoea did not develop, and body weight increased. The feed was life-saving: the patients' superficial veins were thrombosed, and percaval feeding was considered undesirable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201963"} {"pmid": "4201966", "title": "The modes of inhibitory effects of PCBs on oxidative phosphorylation of mitochondria.", "content": "The modes of inhibitory effects of PCBs on oxidative phosphorylation of mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201966"} {"pmid": "4201969", "title": "Introductory remarks: new agents in psychiatry.", "content": "Introductory remarks: new agents in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201969"} {"pmid": "4201970", "title": "Chemistry of trazodone.", "content": "Chemistry of trazodone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201970"} {"pmid": "4201971", "title": "Pharmacology of trazodone.", "content": "Pharmacology of trazodone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201971"} {"pmid": "4201972", "title": "Clinical experience with a new psychotropic drug, trazodone: a review of literature.", "content": "Clinical experience with a new psychotropic drug, trazodone: a review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201972"} {"pmid": "4201973", "title": "Systematic clinical studies with trazodone: methodological aspects.", "content": "Systematic clinical studies with trazodone: methodological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201973"} {"pmid": "4201974", "title": "Trazodone in the treatment of organic brain syndromes, with special reference to psychogeriatrics.", "content": "Trazodone in the treatment of organic brain syndromes, with special reference to psychogeriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201974"} {"pmid": "4201968", "title": "Cerebral edema unresponsive to conventional therapy in neurosurgical patients with unsuspected nutritional failure.", "content": "Cerebral edema unresponsive to conventional therapy in neurosurgical patients with unsuspected nutritional failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201968"} {"pmid": "4201975", "title": "Trazodone in the treatment of schizophrenias.", "content": "Trazodone in the treatment of schizophrenias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201975"} {"pmid": "4201976", "title": "Trazodone in the treatment of affective disorders.", "content": "Trazodone in the treatment of affective disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201976"} {"pmid": "4201977", "title": "Trazodone and psychosomatic medicine.", "content": "Trazodone and psychosomatic medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201977"} {"pmid": "4201978", "title": "Trazodone in the treatment of psychoneuroses: a double-blind study.", "content": "Trazodone in the treatment of psychoneuroses: a double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201978"} {"pmid": "4201981", "title": "A comparison of 4-hydroxybenzoic acid hydrazide (PAHBAH) with other reagents for the determination of glucose.", "content": "A comparison of 4-hydroxybenzoic acid hydrazide (PAHBAH) with other reagents for the determination of glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201981"} {"pmid": "4201982", "title": "A correlation of radiographic, functional, and morphologic changes in baboon lung allografts. A comparison of two immunosuppressive regimens.", "content": "A correlation of radiographic, functional, and morphologic changes in baboon lung allografts. A comparison of two immunosuppressive regimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201982"} {"pmid": "4201983", "title": "Transplantation of the lung. Correlation of physiologic, immunologic, and histologic findings.", "content": "Transplantation of the lung. Correlation of physiologic, immunologic, and histologic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201983"} {"pmid": "4201987", "title": "Malaria debriefing: experience with 1552 returnees from Southeast Asia.", "content": "Malaria debriefing: experience with 1552 returnees from Southeast Asia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201987"} {"pmid": "4201988", "title": "Clinical and serological responses to plague vaccine U.S.P.", "content": "Clinical and serological responses to plague vaccine U.S.P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201988"} {"pmid": "4201989", "title": "Efficacy of surgery for intervertebral discopathy in military personnel.", "content": "Efficacy of surgery for intervertebral discopathy in military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201989"} {"pmid": "4201990", "title": "The meaning of mottling on the colloidal radiogold liver scan.", "content": "The meaning of mottling on the colloidal radiogold liver scan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201990"} {"pmid": "4201991", "title": "Dermatophytes in military personnel.", "content": "Dermatophytes in military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201991"} {"pmid": "4201992", "title": "Albert Calmette. The Saigon years 1891-1893: A historical review.", "content": "Albert Calmette. The Saigon years 1891-1893: A historical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201992"} {"pmid": "4201993", "title": "Causative factors resulting in the placement of dental restorations: A survey of 8891 restorations.", "content": "Causative factors resulting in the placement of dental restorations: A survey of 8891 restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201993"} {"pmid": "4201994", "title": "Use of psychotherapeutic drugs in the acute detoxification of heroin addicts.", "content": "Use of psychotherapeutic drugs in the acute detoxification of heroin addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201994"} {"pmid": "4201986", "title": "Changes in red cell carbonic anhydrase B and serum iodothyronines in hyperthyroid subjects following 131-I treatment.", "content": "Changes in red cell carbonic anhydrase B and serum iodothyronines in hyperthyroid subjects following 131-I treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201986"} {"pmid": "4201995", "title": "Editorial: The military as a leader in the struggle against atherosclerosis.", "content": "Editorial: The military as a leader in the struggle against atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201995"} {"pmid": "4201997", "title": "Proceedings: Cromolyn sodium. A panel discussion.", "content": "Proceedings: Cromolyn sodium. A panel discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201997"} {"pmid": "4201996", "title": "Mutations as possible replication errors in bacteria growing under conditions of thymine deficiency.", "content": "Mutations as possible replication errors in bacteria growing under conditions of thymine deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201996"} {"pmid": "4202003", "title": "Effect of restricted use of phosphate-based detergents on Onondaga Lake.", "content": "Effect of restricted use of phosphate-based detergents on Onondaga Lake. A marked decrease in the concentration of total inorganic phosphate in the epilimnion and hypolimnion of Onondaga Lake, New York State, has been observed during the 1(1/2) years between July 1971 and January 1973. This decrease has been correlated to the implementation of phosphate-limiting legislation. The response of characteristic plankton species has been investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202003"} {"pmid": "4202002", "title": "Diphtheria.", "content": "Diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202002"} {"pmid": "4202004", "title": "Biliary atresia: the current state of confusion.", "content": "Biliary atresia: the current state of confusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202004"} {"pmid": "4201999", "title": "Trypanosoma cruzi infections in Rhodnius prolixus refed on different hosts.", "content": "Trypanosoma cruzi infections in Rhodnius prolixus refed on different hosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4201999"} {"pmid": "4202007", "title": "Bovine mycoplasmas: serological studies by double immunodiffusion, growth precipitation and growth inhibition.", "content": "Bovine mycoplasmas: serological studies by double immunodiffusion, growth precipitation and growth inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202007"} {"pmid": "4202009", "title": "Serum luteinizing hormone concentrations in male monkeys (Macaca fascicularis).", "content": "Serum luteinizing hormone concentrations in male monkeys (Macaca fascicularis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202009"} {"pmid": "4202008", "title": "Proteases of Clostridium botulinum. IV. Inhibitors against proteases from Clostridium botulinum.", "content": "Proteases of Clostridium botulinum. IV. Inhibitors against proteases from Clostridium botulinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202008"} {"pmid": "4202010", "title": "Fractionation of Listeria monocytogenes serotype 5.", "content": "Fractionation of Listeria monocytogenes serotype 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202010"} {"pmid": "4202013", "title": "Saturation in the competitive protein-binding assay of serum thyroxine.", "content": "Saturation in the competitive protein-binding assay of serum thyroxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202013"} {"pmid": "4202015", "title": "Determination of serum glucose with o-toluidine without glacial acetic acid.", "content": "Determination of serum glucose with o-toluidine without glacial acetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202015"} {"pmid": "4202014", "title": "The presence of furan derivatives in patients receiving fructose-containing solutions intravenously.", "content": "The presence of furan derivatives in patients receiving fructose-containing solutions intravenously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202014"} {"pmid": "4202016", "title": "Serum IgG, IgM and IgA concentration determined by the \"linear plate\" immunodiffusion technique in a normal population.", "content": "Serum IgG, IgM and IgA concentration determined by the \"linear plate\" immunodiffusion technique in a normal population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202016"} {"pmid": "4202018", "title": "Ultrastructure of the 5S RNA locus in salivary gland chromosomes of drosophila melanogaster.", "content": "Ultrastructure of the 5S RNA locus in salivary gland chromosomes of drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202018"} {"pmid": "4202020", "title": "A study of lipoxidase in pea seeds and seedlings.", "content": "A study of lipoxidase in pea seeds and seedlings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202020"} {"pmid": "4202017", "title": "Selection for altered recombination frequency in Drosophila melanogaster.", "content": "Selection for altered recombination frequency in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202017"} {"pmid": "4202022", "title": "Clinicopathologic conference: Acute illness with elevated serum amylase.", "content": "Clinicopathologic conference: Acute illness with elevated serum amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202022"} {"pmid": "4202021", "title": "Nutritive value of processed Saccharomyces cerevisiae, Scenedesmus obliquus and Spirulina platensis as measured by protein synthesis in vitro in rat skeletal muscle.", "content": "Nutritive value of processed Saccharomyces cerevisiae, Scenedesmus obliquus and Spirulina platensis as measured by protein synthesis in vitro in rat skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202021"} {"pmid": "4202023", "title": "Oxypertine and primate behaviour.", "content": "Oxypertine and primate behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202023"} {"pmid": "4202024", "title": "The basic pharmacology of oxypertine.", "content": "The basic pharmacology of oxypertine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202024"} {"pmid": "4202019", "title": "Syntheses of the beta-D-glucosides of 4- and 5-hydroxy-1-naphthyl N-methylcarbamate.", "content": "Syntheses of the beta-D-glucosides of 4- and 5-hydroxy-1-naphthyl N-methylcarbamate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202019"} {"pmid": "4202029", "title": "Defective drug metabolism in rat liver in endotoxin shock.", "content": "Defective drug metabolism in rat liver in endotoxin shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202029"} {"pmid": "4202032", "title": "Biosynthesis of mycolic acids. Formation of a C32 beta-keto ester from palmitic acid in a cell-free system of Corynebacterium diphtheriae.", "content": "Biosynthesis of mycolic acids. Formation of a C32 beta-keto ester from palmitic acid in a cell-free system of Corynebacterium diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202032"} {"pmid": "4202033", "title": "Studies on the biosynthesis of glucolipid in Tetrahymena pyriformis.", "content": "Studies on the biosynthesis of glucolipid in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202033"} {"pmid": "4202035", "title": "Responses of trigeminal units in the monkey bulbar lateral reticular formation to noxious and non-noxious stimulation of the face: experimental and theoretical considerations.", "content": "Responses of trigeminal units in the monkey bulbar lateral reticular formation to noxious and non-noxious stimulation of the face: experimental and theoretical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202035"} {"pmid": "4202036", "title": "Interhemispheric comparison of mirror image stimuli in chiasm-sectioned monkeys.", "content": "Interhemispheric comparison of mirror image stimuli in chiasm-sectioned monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202036"} {"pmid": "4202037", "title": "The relationship of subsurface cisternae and cisternal organs to symmetrical axon terminals in the primate sensorimotor cortex.", "content": "The relationship of subsurface cisternae and cisternal organs to symmetrical axon terminals in the primate sensorimotor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202037"} {"pmid": "4202046", "title": "Sporogony of Leucocytozoon spp. in mammalophilic simuliids.", "content": "Sporogony of Leucocytozoon spp. in mammalophilic simuliids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202046"} {"pmid": "4202040", "title": "The management of chronic pain.", "content": "The management of chronic pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202040"} {"pmid": "4202047", "title": "Correlations between pathological changes in the hind paws of rats with adjuvant arthritis and their response to anti-inflammatory and analgesic drugs.", "content": "Correlations between pathological changes in the hind paws of rats with adjuvant arthritis and their response to anti-inflammatory and analgesic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202047"} {"pmid": "4202049", "title": "Enteric infections in captive monkeys.", "content": "Enteric infections in captive monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202049"} {"pmid": "4202041", "title": "Biochemical tests for cancer.", "content": "Biochemical tests for cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202041"} {"pmid": "4202050", "title": "Serological and prognostic significance of partial absorption anti-human globulin test for incomplete Rh antibodies.", "content": "Serological and prognostic significance of partial absorption anti-human globulin test for incomplete Rh antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202050"} {"pmid": "4202039", "title": "Soft tissue sarcomas: an outline guide to management.", "content": "Soft tissue sarcomas: an outline guide to management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202039"} {"pmid": "4202045", "title": "Unproven methods of cancer management. Gerson method of treatment for cancer.", "content": "Unproven methods of cancer management. Gerson method of treatment for cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202045"} {"pmid": "4202051", "title": "Hepatitis associated antigen amongst blood donors in Delhi by counter-electrophoresis.", "content": "Hepatitis associated antigen amongst blood donors in Delhi by counter-electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202051"} {"pmid": "4202043", "title": "Carcinoma of the stomach.", "content": "Carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202043"} {"pmid": "4202052", "title": "A follow-up study on diphtheria carriers among children below 5 years in a rural population of Lucknow District.", "content": "A follow-up study on diphtheria carriers among children below 5 years in a rural population of Lucknow District.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202052"} {"pmid": "4202053", "title": "The scope of oral glibenclamide in the non-ketotic young diabetics.", "content": "The scope of oral glibenclamide in the non-ketotic young diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202053"} {"pmid": "4202044", "title": "Classics in oncology: Johannes Müller (1801-1858).", "content": "Classics in oncology: Johannes Müller (1801-1858).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202044"} {"pmid": "4202054", "title": "Some serological studies on Bacteroides corrodens.", "content": "Some serological studies on Bacteroides corrodens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202054"} {"pmid": "4202055", "title": "Synthesis of lipoic acid by Streptococcus faecalis 10C1 and end-products produced anaerobically from low concentrations of glucose.", "content": "Synthesis of lipoic acid by Streptococcus faecalis 10C1 and end-products produced anaerobically from low concentrations of glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202055"} {"pmid": "4202042", "title": "Newer methods for evaluating thyroid nodules.", "content": "Newer methods for evaluating thyroid nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202042"} {"pmid": "4202056", "title": "Isolation and partial characterization of a temperature-sensitive mutant of Bacillus subtilis impaired in the development of competence for genetic transformation.", "content": "Isolation and partial characterization of a temperature-sensitive mutant of Bacillus subtilis impaired in the development of competence for genetic transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202056"} {"pmid": "4202057", "title": "Intestinal fistulae.", "content": "Intestinal fistulae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202057"} {"pmid": "4202058", "title": "The healthy male carrier of the gonococcus.", "content": "The healthy male carrier of the gonococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202058"} {"pmid": "4202062", "title": "Thought for food.", "content": "Thought for food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202062"} {"pmid": "4202063", "title": "Intravenous feeding of the newborn.", "content": "Intravenous feeding of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202063"} {"pmid": "4202064", "title": "IgA deficiency and autoimmune haemolytic anaemia.", "content": "IgA deficiency and autoimmune haemolytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202064"} {"pmid": "4202065", "title": "Genetic dissection of behavior.", "content": "Genetic dissection of behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202065"} {"pmid": "4202068", "title": "Importance of dilantin blood levels in managing epilepsy.", "content": "Importance of dilantin blood levels in managing epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202068"} {"pmid": "4202076", "title": "Is there a protein problem?", "content": "Is there a protein problem?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202076"} {"pmid": "4202082", "title": "The relation of starvation to hypoglycaemia and adrenocortical activity in newborn and six-week-old piglets.", "content": "The relation of starvation to hypoglycaemia and adrenocortical activity in newborn and six-week-old piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202082"} {"pmid": "4202084", "title": "Permeability of the mammary gland to large antibiotic molecules.", "content": "Permeability of the mammary gland to large antibiotic molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202084"} {"pmid": "4202085", "title": "Observations on the synchronization of oestrus in Sarda sheep.", "content": "Observations on the synchronization of oestrus in Sarda sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202085"} {"pmid": "4202086", "title": "Changes in the cell pattern in vaginal smears of cattle during pregnancy.", "content": "Changes in the cell pattern in vaginal smears of cattle during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202086"} {"pmid": "4202088", "title": "Congenital heart abnormalities in the cat. A description of sixteen cases.", "content": "Congenital heart abnormalities in the cat. A description of sixteen cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202088"} {"pmid": "4202089", "title": "Electron-microscopic changes of the liver and kidneys in chickens treated with tannic acid.", "content": "Electron-microscopic changes of the liver and kidneys in chickens treated with tannic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202089"} {"pmid": "4202090", "title": "An electron microscopical study of the cerebral cortex of the calf. 1. The normal calf.", "content": "An electron microscopical study of the cerebral cortex of the calf. 1. The normal calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202090"} {"pmid": "4202092", "title": "The concept of population in biology. A logical analysis with a suggestion to diminish the confusion of thought.", "content": "The concept of population in biology. A logical analysis with a suggestion to diminish the confusion of thought.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202092"} {"pmid": "4202094", "title": "Diisopropylfluorophosphate uptake by granulocytopoietic cells in chronic myeloid leukaemia and in normal individuals.", "content": "Diisopropylfluorophosphate uptake by granulocytopoietic cells in chronic myeloid leukaemia and in normal individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202094"} {"pmid": "4202093", "title": "Ultrastructural features of phytohemagglutinin and concanavalin A-responsive lymphocytes in chronic lymphocytic leukemia.", "content": "Ultrastructural features of phytohemagglutinin and concanavalin A-responsive lymphocytes in chronic lymphocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202093"} {"pmid": "4202095", "title": "Serum haemopexin concentration in patients with various haemoglobinopathies. Effect of splenectomy.", "content": "Serum haemopexin concentration in patients with various haemoglobinopathies. Effect of splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202095"} {"pmid": "4202096", "title": "Splenic function and infection in sickle cell anemia.", "content": "Splenic function and infection in sickle cell anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202096"} {"pmid": "4202097", "title": "Ribonucleic acid and phytohemagglutinin on rat leukocyte cultures within diffusion chambers.", "content": "Ribonucleic acid and phytohemagglutinin on rat leukocyte cultures within diffusion chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202097"} {"pmid": "4202098", "title": "Study of the effect of actinomycin D on the thrombocytopoiesis of mice, using 75Se-labelled methionine.", "content": "Study of the effect of actinomycin D on the thrombocytopoiesis of mice, using 75Se-labelled methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202098"} {"pmid": "4202100", "title": "Experimental iris suture observed by electronmicroscope. A preliminary report.", "content": "Experimental iris suture observed by electronmicroscope. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202100"} {"pmid": "4202101", "title": "Structure and function of nucleosides and nucleotides.", "content": "Structure and function of nucleosides and nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202101"} {"pmid": "4202102", "title": "Recent results in insect pheromone chemistry.", "content": "Recent results in insect pheromone chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202102"} {"pmid": "4202103", "title": "Solid phase synthesis of peptides with carboxyl-terminal amides--thyrotropin-releasing factor (TRF).", "content": "Solid phase synthesis of peptides with carboxyl-terminal amides--thyrotropin-releasing factor (TRF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202103"} {"pmid": "4202104", "title": "Stereochemistry of the coenzyme-B12-dependent methylamalonyl-CoA-mutase reaction. Investigation with ethylmalonyl-CoA.", "content": "Stereochemistry of the coenzyme-B12-dependent methylamalonyl-CoA-mutase reaction. Investigation with ethylmalonyl-CoA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202104"} {"pmid": "4202105", "title": "Nuclear medicine and radiochemistry.", "content": "Nuclear medicine and radiochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202105"} {"pmid": "4202107", "title": "5'-Nitrates of pyrimidine nucleosides: nitric acid analogs of nucleotides.", "content": "5'-Nitrates of pyrimidine nucleosides: nitric acid analogs of nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202107"} {"pmid": "4202106", "title": "Chemistry and significance of the carbohydrate moieties of human serum glycoproteins.", "content": "Chemistry and significance of the carbohydrate moieties of human serum glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202106"} {"pmid": "4202108", "title": "Methoxymethyl isocyanate as a new agent for reversible protection of SH groups in protein and peptide chemistry.", "content": "Methoxymethyl isocyanate as a new agent for reversible protection of SH groups in protein and peptide chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202108"} {"pmid": "4202109", "title": "The Lutheran, Duffy and Kell blood groups.", "content": "The Lutheran, Duffy and Kell blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202109"} {"pmid": "4202112", "title": "Authropometric and genetic studies in a Russian Old Believer population.", "content": "Authropometric and genetic studies in a Russian Old Believer population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202112"} {"pmid": "4202113", "title": "Ag (x, y, a1, z, t) antigens in a Japanese population.", "content": "Ag (x, y, a1, z, t) antigens in a Japanese population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202113"} {"pmid": "4202114", "title": "An immunological approach to the study of inherited differences in the activity of human erythrocyte phosphoglucose isomerase.", "content": "An immunological approach to the study of inherited differences in the activity of human erythrocyte phosphoglucose isomerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202114"} {"pmid": "4202115", "title": "Absorption studies of iron and vitamin B12 by INMAS whole body counters.", "content": "Absorption studies of iron and vitamin B12 by INMAS whole body counters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202115"} {"pmid": "4202116", "title": "Media for the isolation and preservation of N. gonorrhoeae.", "content": "Media for the isolation and preservation of N. gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202116"} {"pmid": "4202117", "title": "Isolation of Kaisodi virus from ixodid ticks in he Kyasanur Forest disease area of Shimoga district, Mysore State, India.", "content": "Isolation of Kaisodi virus from ixodid ticks in he Kyasanur Forest disease area of Shimoga district, Mysore State, India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202117"} {"pmid": "4202118", "title": "Immunoglobulin specificity of Rh antibodies.", "content": "Immunoglobulin specificity of Rh antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202118"} {"pmid": "4202119", "title": "Localization of sucrase in the microvillous membrane of rabbit intestinal mucosal cells.", "content": "Localization of sucrase in the microvillous membrane of rabbit intestinal mucosal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202119"} {"pmid": "4202120", "title": "Limited proteolysis of human IgG by fruit bromelain.", "content": "Limited proteolysis of human IgG by fruit bromelain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202120"} {"pmid": "4202121", "title": "Difference-spectrophotometry of the interaction of cycloheptaamylose with saccharifying alpha-amylase from Bacillus subtilis.", "content": "Difference-spectrophotometry of the interaction of cycloheptaamylose with saccharifying alpha-amylase from Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202121"} {"pmid": "4202122", "title": "Neutral and amino sugar composition of thyroglobulin. Comparison of the compositions of different fractions of hog thyroglobulin and of thyroglobulins from various animal species.", "content": "Neutral and amino sugar composition of thyroglobulin. Comparison of the compositions of different fractions of hog thyroglobulin and of thyroglobulins from various animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202122"} {"pmid": "4202123", "title": "Studies on mammalian glycosidases. V. Effects of metal ions upon acidic and neutral alpha-glucosidases, beta-galactosidases, and alpha-mannosidases in liver extract of rabbit.", "content": "Studies on mammalian glycosidases. V. Effects of metal ions upon acidic and neutral alpha-glucosidases, beta-galactosidases, and alpha-mannosidases in liver extract of rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202123"} {"pmid": "4202124", "title": "Constant irrelevant cues and stimulus generalization in monkeys.", "content": "Constant irrelevant cues and stimulus generalization in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202124"} {"pmid": "4202125", "title": "Effects of various coronary vasodilators on myocardial oxygen consumption.", "content": "Effects of various coronary vasodilators on myocardial oxygen consumption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202125"} {"pmid": "4202134", "title": "Fine-structural changes of the synovial membrane in arthrosis deformans.", "content": "Fine-structural changes of the synovial membrane in arthrosis deformans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202134"} {"pmid": "4202133", "title": "Glomerulonephritis associated with (infected) ventriculo-atrial shunt.", "content": "Glomerulonephritis associated with (infected) ventriculo-atrial shunt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202133"} {"pmid": "4202139", "title": "Notes on the use of stereological methods in comparative placentology.", "content": "Notes on the use of stereological methods in comparative placentology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202139"} {"pmid": "4202138", "title": "Trace elements in human nutrition. Report of a WHO expert committee.", "content": "Trace elements in human nutrition. Report of a WHO expert committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202138"} {"pmid": "4202140", "title": "Ventricular tracking pacemaker and teletransmitter follow-up system.", "content": "Ventricular tracking pacemaker and teletransmitter follow-up system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202140"} {"pmid": "4202143", "title": "Thyrotropin-releasing hormone as a pituitary-function indicator. A comparison with other tests.", "content": "Thyrotropin-releasing hormone as a pituitary-function indicator. A comparison with other tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202143"} {"pmid": "4202144", "title": "Hypersensitivity pneumonitis in the monkey.", "content": "Hypersensitivity pneumonitis in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202144"} {"pmid": "4202148", "title": "Amino acid transport in the cornea. I. 3-Aminoisobutyric acid uptake in the toad.", "content": "Amino acid transport in the cornea. I. 3-Aminoisobutyric acid uptake in the toad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202148"} {"pmid": "4202149", "title": "Encephalitozoonosis (nosematosis) of the cornea.", "content": "Encephalitozoonosis (nosematosis) of the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202149"} {"pmid": "4202150", "title": "Use of horseradish peroxidase in identification of serum antibodies and immune complexes.", "content": "Use of horseradish peroxidase in identification of serum antibodies and immune complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202150"} {"pmid": "4202151", "title": "Metabolism and metabolic action of lead and other heavy metals.", "content": "Metabolism and metabolic action of lead and other heavy metals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202151"} {"pmid": "4202152", "title": "Toxicity of beryllium and other elements in missile propellants.", "content": "Toxicity of beryllium and other elements in missile propellants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202152"} {"pmid": "4202147", "title": "Cyanophages-viruses attacking blue-green algae.", "content": "Cyanophages-viruses attacking blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202147"} {"pmid": "4202154", "title": "Cessation of deoxyribonucleic acid polymerase activity in amino acid-starved Tetrahymena pyriformis.", "content": "Cessation of deoxyribonucleic acid polymerase activity in amino acid-starved Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202154"} {"pmid": "4202155", "title": "Immune response of guinea pigs to common enterobacterial antigen.", "content": "Immune response of guinea pigs to common enterobacterial antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202155"} {"pmid": "4202156", "title": "Touch epilepsy.", "content": "Touch epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202156"} {"pmid": "4202146", "title": "Chemistry and biology of the polyene macrolide antibiotics.", "content": "Chemistry and biology of the polyene macrolide antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202146"} {"pmid": "4202157", "title": "Immunologic homogeneity and electrophoretic heterogeneity of mouse melanoma tyrosinases.", "content": "Immunologic homogeneity and electrophoretic heterogeneity of mouse melanoma tyrosinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202157"} {"pmid": "4202158", "title": "Pulmonary arterial pressure and structure in the baboon Papio papio.", "content": "Pulmonary arterial pressure and structure in the baboon Papio papio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202158"} {"pmid": "4202159", "title": "The sensitivity of the colloidal carbon technique in measuring pulmonary vascular permeability changes.", "content": "The sensitivity of the colloidal carbon technique in measuring pulmonary vascular permeability changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202159"} {"pmid": "4202160", "title": "Cavitating pulmonary infarct: an unusual complication of parenteral alimentation.", "content": "Cavitating pulmonary infarct: an unusual complication of parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202160"} {"pmid": "4202161", "title": "Letter: Intragastric versus nasojejunal feeding of low-birth-weigh infants.", "content": "Letter: Intragastric versus nasojejunal feeding of low-birth-weigh infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202161"} {"pmid": "4202163", "title": "Mangement of intraurethral condyloma acuminatum.", "content": "Mangement of intraurethral condyloma acuminatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202163"} {"pmid": "4202162", "title": "Cellular and humoral immune response to group B streptococci.", "content": "Cellular and humoral immune response to group B streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202162"} {"pmid": "4202164", "title": "Chemicals used topically for ringworm in Australia.", "content": "Chemicals used topically for ringworm in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202164"} {"pmid": "4202165", "title": "Letter: Prostaglandins, nutmeg and diarrhea.", "content": "Letter: Prostaglandins, nutmeg and diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202165"} {"pmid": "4202166", "title": "Locomotor affinities of Hominoid tali from Kenya.", "content": "Locomotor affinities of Hominoid tali from Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202166"} {"pmid": "4202167", "title": "Gonorrhea amnionitis.", "content": "Gonorrhea amnionitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202167"} {"pmid": "4202168", "title": "Amniotic fluid evaluation after intrauterine transfusion.", "content": "Amniotic fluid evaluation after intrauterine transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202168"} {"pmid": "4202169", "title": "Optimal utilization of Rh immunoglobulin in induced abortion.", "content": "Optimal utilization of Rh immunoglobulin in induced abortion. A study which was designed to characterize and refine methods of identifying, educating, and treating Rh-negative women while monitoring Rh immunoglobulin use in an active abortion service is described. A simple system for the rapid analysis of Rh immunoglobulin use was developed. During a 7-week period, 255 of 265 Rh-negative unimmunized women received Rh immunoglobulin. 9 of the 10 women refusing it were older multiparas. Previous surveys have shown the utilization rates ranging from 42% to 68%. The 96.2% acceptance shown in this study is believed to demonstrate that optimal utilization can be approached with the appropriate procedures. At PRETERM, an out-patient abortion service in Washington, D.C., where this study took place, all women requesting abortion are tested for Rh type by the routine slide method. Serum from each specimen found to be Rh-negative is then tested for the presence of Rh antibody. Results from Rh-negative women are hand carried from the laboratory to the medical area, where the lab results and a vial of Rh immunoglobulin are attached to the patient's chart. The medical receptionist informs the counselor of the patient's blood type before the abortion. The woman and her counselor discuss the implications of Rh-negative blood type and abortion and the use of Rh immunoglobulin. An attempt is made to convince all women of the need for Rh immunoglobulin, regardless of their future child-bearing plans. Immediately after the abortion, with the patient's consent, a nurse administers the Rh immunoglobulin. All used and unused vials are returned to the laboratory. An Rh-negative identification card is given to the patient. There is no additional charge for Rh testing or Rh immunoglobulin. The authors believe that with the increasing incidence of induced abortion, such procedures are vital if Rh immunization and Rh hemolytic disease of the newborn are to be prevented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202169"} {"pmid": "4202175", "title": "Studies on the phospholipase A2 in pyloric caeca of the starfish Asterina pectinifera.", "content": "Studies on the phospholipase A2 in pyloric caeca of the starfish Asterina pectinifera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202175"} {"pmid": "4202176", "title": "Cell-free translation of influenza virus messenger RNA.", "content": "Cell-free translation of influenza virus messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202176"} {"pmid": "4202180", "title": "Ultrastructural basis of toxic hepatitis.", "content": "Ultrastructural basis of toxic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202180"} {"pmid": "4202181", "title": "Adverse reactions to intravenous diazepam: a report from the Boston Collaborative Drug Surveillance Program.", "content": "Adverse reactions to intravenous diazepam: a report from the Boston Collaborative Drug Surveillance Program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202181"} {"pmid": "4202185", "title": "Problems and progress in physiological psychology.", "content": "Problems and progress in physiological psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202185"} {"pmid": "4202186", "title": "Proceedings: Cancer of the kidney--radiation therapy and its indications in non-Wilms' tumors.", "content": "Proceedings: Cancer of the kidney--radiation therapy and its indications in non-Wilms' tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202186"} {"pmid": "4202187", "title": "Proceedings: Diagnosis and staging of prostatic carcinoma.", "content": "Proceedings: Diagnosis and staging of prostatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202187"} {"pmid": "4202188", "title": "Proceedings: Radiation therapy in malignant testis tumors. I: Seminoma; II: Carcinoma.", "content": "Proceedings: Radiation therapy in malignant testis tumors. I: Seminoma; II: Carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202188"} {"pmid": "4202182", "title": "Transfusion with wrong type of blood claimed too late.", "content": "Transfusion with wrong type of blood claimed too late.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202182"} {"pmid": "4202189", "title": "Extended combination therapy of childhood rhabdomyosarcoma.", "content": "Extended combination therapy of childhood rhabdomyosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202189"} {"pmid": "4202190", "title": "Prognostic signs and the management of the mycosis fungoides.", "content": "Prognostic signs and the management of the mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202190"} {"pmid": "4202191", "title": "A controlled study of isolation and endogenous microbial suppression in acute myelocytic leukemia patients.", "content": "A controlled study of isolation and endogenous microbial suppression in acute myelocytic leukemia patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202191"} {"pmid": "4202193", "title": "The identification of two protease inhibitors in Drosophila melanogaster.", "content": "The identification of two protease inhibitors in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202193"} {"pmid": "4202192", "title": "Binding of tryptophan to plasma proteins in several species.", "content": "Binding of tryptophan to plasma proteins in several species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202192"} {"pmid": "4202194", "title": "Characterization of an unstable carbonic anhydrase (CAII) variant in the guinea pig (Cavia porcellus).", "content": "Characterization of an unstable carbonic anhydrase (CAII) variant in the guinea pig (Cavia porcellus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202194"} {"pmid": "4202196", "title": "[Oxygen uptake and heat production of cynomolgus monkey (Macaca irus) in a primate restraining chair at ambient temperature of 25 degrees C and 10 degrees C (author's transl)].", "content": "[Oxygen uptake and heat production of cynomolgus monkey (Macaca irus) in a primate restraining chair at ambient temperature of 25 degrees C and 10 degrees C (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202196"} {"pmid": "4202198", "title": "Thymineless death in Lactobacillus acidophilus R-26. II. Factors determining the rate of the reproductive inactivation.", "content": "Thymineless death in Lactobacillus acidophilus R-26. II. Factors determining the rate of the reproductive inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202198"} {"pmid": "4202199", "title": "Productivity and heat generation of fermentation under oxygen limitation.", "content": "Productivity and heat generation of fermentation under oxygen limitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202199"} {"pmid": "4202202", "title": "Increased resistance to malaria after Mycobacterium tuberculosis infection.", "content": "Increased resistance to malaria after Mycobacterium tuberculosis infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202202"} {"pmid": "4202201", "title": "Regulation of biosynthesis of excessive metabolites. XIV. Incorporation of (U-14C) asparagine into the molecule of tetracycline.", "content": "Regulation of biosynthesis of excessive metabolites. XIV. Incorporation of (U-14C) asparagine into the molecule of tetracycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202201"} {"pmid": "4202200", "title": "The interaction of protein substrates (antigens) during an in vitro degradation by rabbit cathepsin D.", "content": "The interaction of protein substrates (antigens) during an in vitro degradation by rabbit cathepsin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202200"} {"pmid": "4202203", "title": "Personal health expenses among rural communities of North Arcot District.", "content": "Personal health expenses among rural communities of North Arcot District.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202203"} {"pmid": "4202204", "title": "Nutritional assessment of rural pre-school children.", "content": "Nutritional assessment of rural pre-school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202204"} {"pmid": "4202205", "title": "The effect of trimethoprim on the activity of sulfonamides and antibiotics in experimental infections.", "content": "The effect of trimethoprim on the activity of sulfonamides and antibiotics in experimental infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202205"} {"pmid": "4202207", "title": "Distribution of trimethoprim-sulfamethoxazole in tissues of rhesus monkeys.", "content": "Distribution of trimethoprim-sulfamethoxazole in tissues of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202207"} {"pmid": "4202206", "title": "Antibacterial action of trimethoprim-sulfamethoxazole.", "content": "Antibacterial action of trimethoprim-sulfamethoxazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202206"} {"pmid": "4202208", "title": "Various regimens of trimethoprim-sulfamethoxazole used in the treatment of gonorrhea.", "content": "Various regimens of trimethoprim-sulfamethoxazole used in the treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202208"} {"pmid": "4202209", "title": "Trimethoprim-sulfamethoxazole in the treatment of infections of the ears, nose, and throat.", "content": "Trimethoprim-sulfamethoxazole in the treatment of infections of the ears, nose, and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202209"} {"pmid": "4202210", "title": "Effects of trimethoprim and sulfisoxazole, alone and in combination, on growth and carriage of Neisseria meningitidis.", "content": "Effects of trimethoprim and sulfisoxazole, alone and in combination, on growth and carriage of Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202210"} {"pmid": "4202211", "title": "Trimethoprim-sulfamethoxazole in the treatment of typhoid and paratyphoid fevers.", "content": "Trimethoprim-sulfamethoxazole in the treatment of typhoid and paratyphoid fevers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202211"} {"pmid": "4202212", "title": "Treatment of chronic carriers of Salmonella typhi and Salmonella paratyphi B with trimethoprim-sulfamethoxazole.", "content": "Treatment of chronic carriers of Salmonella typhi and Salmonella paratyphi B with trimethoprim-sulfamethoxazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202212"} {"pmid": "4202213", "title": "Phenylmorphan agonists-antagonists.", "content": "Phenylmorphan agonists-antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202213"} {"pmid": "4202214", "title": "Synthesis and antibacterial activity of some substituted 4-quinolone-3-carboxylic acids.", "content": "Synthesis and antibacterial activity of some substituted 4-quinolone-3-carboxylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202214"} {"pmid": "4202215", "title": "Synthesis and antimalarial effects of 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine and related substances.", "content": "Synthesis and antimalarial effects of 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202215"} {"pmid": "4202216", "title": "The lambda head-tail joining reaction: purification, properties and structure of biologically active heads and tails.", "content": "The lambda head-tail joining reaction: purification, properties and structure of biologically active heads and tails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202216"} {"pmid": "4202217", "title": "Distribution of histone messenger RNA among free and membrane-associated polyribosomes of a mouse myeloma cell line.", "content": "Distribution of histone messenger RNA among free and membrane-associated polyribosomes of a mouse myeloma cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202217"} {"pmid": "4202218", "title": "Amino acid sequence of lysozyme from baboon milk.", "content": "Amino acid sequence of lysozyme from baboon milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202218"} {"pmid": "4202219", "title": "Chemical modification of lincomycin: synthesis and bioactivity of selected 2,7-dialkylcarbonate esters.", "content": "Chemical modification of lincomycin: synthesis and bioactivity of selected 2,7-dialkylcarbonate esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202219"} {"pmid": "4202220", "title": "Mesoionic purinone analogs. IV. Synthesis and in vitro antibacterial properties of mesoionic thiazolo(3,2-a)pyrimidin-5,7-diones and mesoionic 1,3,4-thiadizolo(3,2-a)pyrimidin-5,7-diones.", "content": "Mesoionic purinone analogs. IV. Synthesis and in vitro antibacterial properties of mesoionic thiazolo(3,2-a)pyrimidin-5,7-diones and mesoionic 1,3,4-thiadizolo(3,2-a)pyrimidin-5,7-diones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202220"} {"pmid": "4202221", "title": "Electrokinetic studies of bacteria. 3. Effect of polyvalent metal ions on electrophoretic mobility and growth of Streptococcus faecalis.", "content": "Electrokinetic studies of bacteria. 3. Effect of polyvalent metal ions on electrophoretic mobility and growth of Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202221"} {"pmid": "4202222", "title": "Microbial food chains and food webs.", "content": "Microbial food chains and food webs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202222"} {"pmid": "4202224", "title": "Dual classification of tympanoplasty.", "content": "Dual classification of tympanoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202224"} {"pmid": "4202225", "title": "Conserved terminal sequence in 18SrRNA may represent terminator anticodons.", "content": "Conserved terminal sequence in 18SrRNA may represent terminator anticodons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202225"} {"pmid": "4202226", "title": "DNA-binding proteins specific for cells infected by adenovirus.", "content": "DNA-binding proteins specific for cells infected by adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202226"} {"pmid": "4202227", "title": "Multiple heavy chains classes and light chain types on surfaces of cultured human lymphoid cells.", "content": "Multiple heavy chains classes and light chain types on surfaces of cultured human lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202227"} {"pmid": "4202228", "title": "Successive visual discrimination performance in the monkey with brief stimuli.", "content": "Successive visual discrimination performance in the monkey with brief stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202228"} {"pmid": "4202229", "title": "Measurement of pituitary hormones: clinical applications. 4. Thyroid stimulating hormone.", "content": "Measurement of pituitary hormones: clinical applications. 4. Thyroid stimulating hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202229"} {"pmid": "4202230", "title": "Organochlorine pesticide residues and polychlorinated biphenyls in human milk, Colorado--1971-72.", "content": "Organochlorine pesticide residues and polychlorinated biphenyls in human milk, Colorado--1971-72.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202230"} {"pmid": "4202231", "title": "Eggshell thinning, chlorinated hydrocarbons, and mercury in inland aquatic bird eggs, 1969 and 1970.", "content": "Eggshell thinning, chlorinated hydrocarbons, and mercury in inland aquatic bird eggs, 1969 and 1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202231"} {"pmid": "4202232", "title": "International cooperative study of organochlorine and mercury residues in wildlife, 1969-71.", "content": "International cooperative study of organochlorine and mercury residues in wildlife, 1969-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202232"} {"pmid": "4202233", "title": "Organochlorine pesticides and polychlorinated biphenyls in black duck eggs from the United States and Canada--1971.", "content": "Organochlorine pesticides and polychlorinated biphenyls in black duck eggs from the United States and Canada--1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202233"} {"pmid": "4202236", "title": "Actinic keratoses in Bantu albinos. Clinical experiences with the topical use of 5-fluoro-uracil.", "content": "Actinic keratoses in Bantu albinos. Clinical experiences with the topical use of 5-fluoro-uracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202236"} {"pmid": "4202237", "title": "A one-year survey of a rural orthopaedic clinic in Zululand.", "content": "A one-year survey of a rural orthopaedic clinic in Zululand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202237"} {"pmid": "4202239", "title": "Dysentery and colienterocolitis. Some aspects of pathogenesis and pathological anatomy.", "content": "Dysentery and colienterocolitis. Some aspects of pathogenesis and pathological anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202239"} {"pmid": "4202238", "title": "Age-induced changes of cerebral arteries in rats. An electron microscope study.", "content": "Age-induced changes of cerebral arteries in rats. An electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202238"} {"pmid": "4202240", "title": "Dysplastic gliosis (spongioblastosis) and the Rosenthal fibres. Pathogenetic contributions.", "content": "Dysplastic gliosis (spongioblastosis) and the Rosenthal fibres. Pathogenetic contributions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202240"} {"pmid": "4202241", "title": "Morphogenesis of plasmatic arterionecrosis as the cause of hypertensive intracerebral hemorrhage.", "content": "Morphogenesis of plasmatic arterionecrosis as the cause of hypertensive intracerebral hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202241"} {"pmid": "4202246", "title": "Upper gastrointestinal radiologic findings in hyperlipoproteinemic subjects.", "content": "Upper gastrointestinal radiologic findings in hyperlipoproteinemic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202246"} {"pmid": "4202247", "title": "Protein--energy deficiency in nonhuman primates: biochemical and morphological alterations.", "content": "Protein--energy deficiency in nonhuman primates: biochemical and morphological alterations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202247"} {"pmid": "4202248", "title": "Evidence for intestinal malabsorption of iodine in protein-calorie malnutrition.", "content": "Evidence for intestinal malabsorption of iodine in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202248"} {"pmid": "4202249", "title": "Essential fatty acid deficiency in red cells after thermal injury: correction with intravenous fat therapy.", "content": "Essential fatty acid deficiency in red cells after thermal injury: correction with intravenous fat therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202249"} {"pmid": "4202250", "title": "Protein-calorie malnutrition in Egypt. I. Immunoelectrophoretic studies on urinary proteins.", "content": "Protein-calorie malnutrition in Egypt. I. Immunoelectrophoretic studies on urinary proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202250"} {"pmid": "4202251", "title": "Pulmonary aspergillosis caused by Aspergillus fischeri var. spinosus: report of a case and value of serologic studies.", "content": "Pulmonary aspergillosis caused by Aspergillus fischeri var. spinosus: report of a case and value of serologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202251"} {"pmid": "4202252", "title": "Monoclonal IgG-lysozyme (muramidase) complex in acute myelomonocytic leukemia: an unusual finding.", "content": "Monoclonal IgG-lysozyme (muramidase) complex in acute myelomonocytic leukemia: an unusual finding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202252"} {"pmid": "4202253", "title": "Multiple diverticula of the esophagus.", "content": "Multiple diverticula of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202253"} {"pmid": "4202254", "title": "Intestinal neurofibromas in von Recklinghausen's disease.", "content": "Intestinal neurofibromas in von Recklinghausen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202254"} {"pmid": "4202255", "title": "Serum and amniotic fluid lactic dehydrogenase in pregnant women.", "content": "Serum and amniotic fluid lactic dehydrogenase in pregnant women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202255"} {"pmid": "4202256", "title": "Chronic manganese intoxication.", "content": "Chronic manganese intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202256"} {"pmid": "4202257", "title": "Editorial: Nourishment in illness.", "content": "Editorial: Nourishment in illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202257"} {"pmid": "4202258", "title": "Some aspects of parenteral nutrition.", "content": "Some aspects of parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202258"} {"pmid": "4202259", "title": "Quartan malarial infections in Aotus trivirgatus with special reference to renal pathology.", "content": "Quartan malarial infections in Aotus trivirgatus with special reference to renal pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202259"} {"pmid": "4202261", "title": "Candida albicans septicaemia during first half of pregnancy successfully treated with 5-fluorocytosine.", "content": "Candida albicans septicaemia during first half of pregnancy successfully treated with 5-fluorocytosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202261"} {"pmid": "4202262", "title": "Editorial: Struggle with malaria.", "content": "Editorial: Struggle with malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202262"} {"pmid": "4202260", "title": "Combined test for assessment of anterior pituitary function.", "content": "Combined test for assessment of anterior pituitary function. A combined test consisting of the simultaneous administration of insulin, thyrotrophin-releasing hormone (TRH), and luteinizing hormone and follicle stimulating hormone-releasing hormone (LH/FSH-RH) was performed in 24 people. Eleven of these also had the three individual tests performed separately, and the remaining 13 had a separate test of either LH/FSH-RH and TRH together or singly at a later date. In both normal people and patients, whether the tests were performed alone or in combination, no difference was found between the hormone responses (growth hormone, cortisol, LH, FSH, thyroid-stimulating hormone) seen to these stimuli.It is proposed that combined administration of insulin and the hypothalamic releasing hormones may be used as a single test for the assessment of anterior pituitary function. The test is convenient and time saving, and with care can be performed in outpatients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202260"} {"pmid": "4202263", "title": "Letter: Brachial plexus palsy after parenteral feeding.", "content": "Letter: Brachial plexus palsy after parenteral feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202263"} {"pmid": "4202264", "title": "New type of allergic asthma due to IgG \"reaginic\" antibody.", "content": "New type of allergic asthma due to IgG \"reaginic\" antibody. This study was undertaken to examine the possibility that IgE is not the only immunoglobulin responsible for immediate allergic reactions. A group of asthmatics were investigated in whom immediate allergic reactivity of the bronchi to common inhalant allergens had been confirmed by provocation tests. Their sera were fractionated and the reaginic activity of the immunoglobulin classes was studied by passive cutaneous anaphylaxis testing in monkeys. The results showed that the immediate allergic reactions were due to IgE antibodies in most patients, but there was a group with reactions due to short-term anaphylactic IgG antibodies. It was not possible to inhibit the IgG-mediated responses with disodium cromoglycate. As these two groups had clearly different serum IgE levels the estimation of IgE provided an important guide to the management of these patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202264"} {"pmid": "4202266", "title": "Letter: Thyrotrophin-releasing hormone, prolactin, and cholesterol.", "content": "Letter: Thyrotrophin-releasing hormone, prolactin, and cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202266"} {"pmid": "4202265", "title": "Cefoxitin, a new semi-synthetic cephamycin: an in-vitro and in-vivo comparison with cephalothin.", "content": "Cefoxitin, a new semi-synthetic cephamycin: an in-vitro and in-vivo comparison with cephalothin. The activity of cefoxitin was compared with that of cephalothin against 229 bacterial strains. Cefoxitin was more active against most Gram-negative strains, notably against indole-producing Proteus spp., which are usually resistant to the cephalosporins. Cefoxitin was not susceptible to any significant extent to degradation by beta-lactamases produced by Gram-negative organisms. Against Gram-positive organisms, however, cefoxitin was considerably less active than cephalothin, but minimum inhibitory concentrations for Staphylococcus aureus were well within therapeutically attainable blood levels.Pharmacokinetic studies in 18 volunteers showed a higher and longer sustained antibiotic activity in serum and urine after injections of cefoxitin than after equal doses of cephalothin. Urinary recovery of cefoxitin activity was also much higher than that of cephalothin. No evidence of toxicity due to cefoxitin was found. Cefoxitin was slightly less painful after intramuscular injection than cephalothin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202265"} {"pmid": "4202270", "title": "Prostaglandin F2a and primate corpus luteum: a correlation of structure and function.", "content": "Prostaglandin F2a and primate corpus luteum: a correlation of structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202270"} {"pmid": "4202272", "title": "The effect of a chemically defined diet on the faecal flora and faecal steroid concentration.", "content": "The effect of a chemically defined diet on the faecal flora and faecal steroid concentration. The consumption of a chemically defined diet altered both the faecal flora and faecal steroids. Enterobacteria increased while enterococci and other lactic acid bacteria decreased in number. No other obvious change occurred. However, the alteration in the degree of degradation of the faecal neutral steroids may reflect some alteration in the anaerobic flora. Total excretion of both acid and neutral steroids was also reduced. On cessation of the diet both faecal flora and faecal steroids reverted to levels before the diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202272"} {"pmid": "4202271", "title": "Postoperative intraperitoneal adhesions: a double-blind assessment of their prevention in the monkey.", "content": "Postoperative intraperitoneal adhesions: a double-blind assessment of their prevention in the monkey. The effect of combined antihistamine and corticosteroid therapy and the effect of dextran on recurrent intraperitoneal adhesion formation were evaluated in 43 monkeys, all of which had been previously used for reproductive tract studies, and, hence, were suffering from adhesion formation to some degree. In a double-blind manner, the monkeys were randomly divided into 3 experimental groups. 1 group received saline injections before and after lysis surgery followed by introduction of saline solution in the peritoneum during surgery. Group 2 was treated with saline injections, as Group 1, except that dextran solution was introduced into the peritoneal cavity. In Group 3, a combined dexamethasone/promethazine therapy was administered before, during, and after surgery. In all of these monkeys, the degree of adhesion reformation after adhesion lysis surgery was essentially the same in all 3 groups. Rather, careful surgical technique was vastly more important than use of corticosteroids or antihistamines as prophylactic measures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202271"} {"pmid": "4202273", "title": "Proceedings: The distribution of vasoactive intestinal peptide (VIP) in the primate gastrointestinal tract and characterization of VIP from human tumours.", "content": "Proceedings: The distribution of vasoactive intestinal peptide (VIP) in the primate gastrointestinal tract and characterization of VIP from human tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202273"} {"pmid": "4202274", "title": "Proceedings: Comparative effect of intravenous and oral nutrition of intestinal adaptation.", "content": "Proceedings: Comparative effect of intravenous and oral nutrition of intestinal adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202274"} {"pmid": "4202277", "title": "Avulsion of lumbar roots complicating fracture of the pelvis.", "content": "Avulsion of lumbar roots complicating fracture of the pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202277"} {"pmid": "4202276", "title": "Pseudomonas vertebral osteomyelitis in heroin addicts. Report of five cases.", "content": "Pseudomonas vertebral osteomyelitis in heroin addicts. Report of five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202276"} {"pmid": "4202278", "title": "Gold distribution in whole blood during chrysotherapy.", "content": "Gold distribution in whole blood during chrysotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202278"} {"pmid": "4202279", "title": "Beta-glucuronidase deficiency mucopolysaccharidosis: methods for enzymatic diagnosis.", "content": "Beta-glucuronidase deficiency mucopolysaccharidosis: methods for enzymatic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202279"} {"pmid": "4202280", "title": "Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys.", "content": "Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202280"} {"pmid": "4202275", "title": "Mental disorders associated with industrial head injury.", "content": "Mental disorders associated with industrial head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202275"} {"pmid": "4202324", "title": "Editorial: Gonococcocidal action of copper.", "content": "Editorial: Gonococcocidal action of copper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202324"} {"pmid": "4202325", "title": "Editorial: Gallstones and estrogens.", "content": "Editorial: Gallstones and estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202325"} {"pmid": "4202326", "title": "Letter: Diagnosis of Fabry's disease by tear alpha-galactosidase A.", "content": "Letter: Diagnosis of Fabry's disease by tear alpha-galactosidase A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202326"} {"pmid": "4202327", "title": "A fate map of larval organs of Drosophila and preblastoderm determination.", "content": "A fate map of larval organs of Drosophila and preblastoderm determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202327"} {"pmid": "4202328", "title": "Thymosin-producing cells of the thymus.", "content": "Thymosin-producing cells of the thymus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202328"} {"pmid": "4202329", "title": "The effect of capping H-2 antigens on the susceptibility of target cells to humoral and T cell-mediated lysis.", "content": "The effect of capping H-2 antigens on the susceptibility of target cells to humoral and T cell-mediated lysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202329"} {"pmid": "4202331", "title": "Regulation of rat liver beta-hydroxy-beta-methylglutaryl-CoA reductase activity by cholesterol.", "content": "Regulation of rat liver beta-hydroxy-beta-methylglutaryl-CoA reductase activity by cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202331"} {"pmid": "4202330", "title": "Hypothalamic interaction between prostaglandins and catecholamines in promoting gonadotrophin secretion for ovulation.", "content": "Hypothalamic interaction between prostaglandins and catecholamines in promoting gonadotrophin secretion for ovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202330"} {"pmid": "4202332", "title": "Lead poisoning in childhood: a case report with environmental implications.", "content": "Lead poisoning in childhood: a case report with environmental implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202332"} {"pmid": "4202333", "title": "Immunoglobulins in normal porcine tracheobronchial secretions.", "content": "Immunoglobulins in normal porcine tracheobronchial secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202333"} {"pmid": "4202334", "title": "Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions.", "content": "Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions. Foreign body multinucleate giant cells were produced by the implantation of a strip of Melenex in the subcutaneous tissues of mice. The implants were removed at various intervals, and the proportion of multinucleate giant cells as well as the number of nuclei they contained were counted and statistically assessed. The greatest proportion of giant cells was reached 4 weeks after implantation, when 25% of the attached cells were multinucleated. The mean nuclear content however was greatest approximately 2 weeks after implantation and rapidly fell over the ensuing weeks. The fusion potential however, remained almost unaltered for the remainder of the experimental period. Transplantation of 7-day Melenex implants from normal donors into lethally irradiated recipients demonstrated that the halflife of the giant cells is only a few days. Treatment with carrageenin, species-specific antisera, actinomycin D and cortisone inhibited, while puromycin enhanced, multinucleate cell formation. Calcium gluconate, EDTA and irradiation had no significant effect. The possible interpretation of some of these findings is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202334"} {"pmid": "4202335", "title": "Pathology of Bolivian hemorrhagic fever in the rhesus monkey.", "content": "Pathology of Bolivian hemorrhagic fever in the rhesus monkey. Gross and microscopic lesions associated with Bolivan hemorrhagic fever virus infection in the rhesus monkey were studied in 10 animals which died following inoculation. Gross lesions included skin rash, lymphadenopathy, splenomegaly, meningeal edema, hydropericardium and enlarged friable livers. Hemorrhagic manifestations of the infection were not consistently observed, but hemorrhages were present in the skin, heart, brain and nares in some monkeys. Histopathologic lesions were fairly consistent. Hepatic necrosis with the presence of acidophilic hyaline bodies, necrotizing enteritis, epithelial necrosis and adrenal cortical necrosis were present in all monkeys. Those monkeys which died after the seventeenth day of infection had nonsupurative meningoencephalitis; lymphoid necrosis was present in 3 monkeys that died after day 18. Other microscopic lesions included myocardial degeneration, lymphoid and reticuloendothelial cell hyperplasia and lymphoid depletion. Most of the histopathologic lesions described in human autopsy material were reproduced; however, the necrosis in the skin and oral mucosa, mucosa of the gastrointestinal tract and the adrenal cortex have not been described in man. Despite these apparent discrepancies the results of this investigation indicate that the rhesus monkey is a good experimental model for the study of Bolivian hemorrhagic fever infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202335"} {"pmid": "4202336", "title": "Mechanism of hyperalimentation in the suppression of upper gastrointestinal secretions.", "content": "Mechanism of hyperalimentation in the suppression of upper gastrointestinal secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202336"} {"pmid": "4202337", "title": "Congenital duodenal atresia.", "content": "Congenital duodenal atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202337"} {"pmid": "4202340", "title": "Screening and isolation of penicillinase inhibitor, KA-107.", "content": "Screening and isolation of penicillinase inhibitor, KA-107. It is known that penicillin resistance of bacteria is mainly caused by the inactivation of penicillin by penicillinase derived from such strains. We have developed a screening procedure for penicillinase inhibitors. Several microorganisms were found to produce such inhibitors, and from the culture filtrate of Streptomyces gedanensis ATCC 4880 a penicillinase inhibitor, named KA-107, was isolated. The characteristics of this inhibitor were revealed by an in vitro test by using penicillinase derived from penicillin resistant Staphylococcus aureus, FS-1277. When KA-107 was used in combination with penicillin-G, ampicillin, d- or l-phenethicillin, the growth inhibitory activity of these penicillins was maintained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202340"} {"pmid": "4202339", "title": "Protein synthesis in Mycobacterium tuberculosis H37Rv and the effect of streptomycin in streptomycin-susceptible and -resistant strains.", "content": "Protein synthesis in Mycobacterium tuberculosis H37Rv and the effect of streptomycin in streptomycin-susceptible and -resistant strains. An efficient in vitro amino acid-incorporating system from Mycobacterium tuberculosis H37Rv was standardized. Ribonucleic acid (RNA) isolated from phage-infected M. smegmatis cells served as natural messenger RNA and directed the incorporation of (14)C-amino acids into protein. The effects of various antitubercular drugs and \"known inhibitors\" of protein synthesis on amino acid incorporation were studied. Antibiotics like chloramphenicol and tetracycline inhibited mycobacterial protein synthesis, though they failed to prevent the growth of the organism. This failure was shown to be due to the impermeability of mycobacteria to these drugs by use of \"membrane-active\" agents along with the antibiotics in growth inhibition studies. Several independent streptomycin-resistant mutants of M. tuberculosis H37Rv were isolated. Streptomycin inhibited the incorporation of (14)C-amino acids into proteins by whole cells of a streptomycin-susceptible strain by more than 90%, whereas very little or no inhibition was observed in either high-level or low-level streptomycin-resistant strains. In vitro, streptomycin was an effective inhibitor of susceptible strains, whereas in streptomycin-resistant strains the concentration of streptomycin at which half-maximal inhibition was produced varied according to the resistance of whole cells, and there was a correlation between the two. In one low-level streptomycin-resistant mutant, the in vitro amino acid-incorporating system was as sensitive to various concentrations of streptomycin as the parental type, and a possible involvement of a membrane site in the development of low-level resistance was indicated. Streptomycin susceptibility and high-level resistance were shown to be ribosomal in nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202339"} {"pmid": "4202341", "title": "Additional antibiotic inhibitors of peptidoglycan synthesis.", "content": "Additional antibiotic inhibitors of peptidoglycan synthesis. Diumycin, janiemycin, nisin, and subtilin inhibited peptidoglycan synthesis catalyzed by particulate enzyme systems from Bacillus stearothermophilus and Escherichia coli. All of these, except for nisin, also induced accumulation of the lipid intermediate in peptidoglycan synthesis. Concentrations required for 50% inhibition of peptidoglycan synthesis were less than 0.1 mug/ml for diumycin and in the range of 10 to 100 mug/ml for janiemycin, nisin, and subtilin in both organisms. The discrepancy between the extremely low concentration of diumycin required to inhibit the in vitro system from E. coli and the much higher concentration required to inhibit growth of the organism is noteworthy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202341"} {"pmid": "4202342", "title": "Studies on the susceptibility of 150 consecutive clinical isolates of Pseudomonas aeruginosa to tobramycin, gentamicin, colistin, carbenicillin, and five other antimicrobials.", "content": "Studies on the susceptibility of 150 consecutive clinical isolates of Pseudomonas aeruginosa to tobramycin, gentamicin, colistin, carbenicillin, and five other antimicrobials. The in vitro susceptibilities of 150 clinical isolates of Pseudomonas aeruginosa to the aminoglycoside tobramycin and eight other antimicrobials were evaluated. The Food and Drug Administration standardized disk diffusion method showed that tobramycin inhibited 100% of the 150 isolates with gentamicin inhibiting only 90.7%. The difference between colistin (97.3%) and tobramycin was less marked. Carbenicillin (87.3%) was found to be slightly less active than gentamicin. Only a small percentage of the isolates were inhibited by the other drugs used. By using a minimal inhibitory concentration of 4 mug/ml in brain heart infusion broth as the level of susceptibility, it was found that only three of the isolates showed resistance to tobramycin, whereas 20 of the isolates were resistant to gentamicin. Approximately half of the isolates were inhibited by 0.5 mug/ml or less of tobramycin, whereas 1.5 mug of gentamicin per ml was required to inhibit 50% of susceptible strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202342"} {"pmid": "4202344", "title": "Lipid composition of gram-negative bacteria, sensitive and resistant to streptomycin.", "content": "Lipid composition of gram-negative bacteria, sensitive and resistant to streptomycin. Analyses of streptomycin-sensitive and -resistant gram-negative bacteria show that, contrary to previous reports, the development of antibiotic resistance is not accompanied by changes in membrane lipid or fatty acid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202344"} {"pmid": "4202343", "title": "In vitro activity of cephalothin and three penicillins against Escherichia coli and Proteus species.", "content": "In vitro activity of cephalothin and three penicillins against Escherichia coli and Proteus species. The susceptibility of clinical isolates of Escherichia coli (67) and Proteus species (58) to cephalothin, ampicillin, benzyl penicillin, and phenoxymethyl penicillin was determined in vitro by using broth dilution and disk diffusion tests. The data were correlated by using a four-category scheme for interpreting minimal inhibitory concentrations (groups 1 to 4) as recommended by a subcommittee of an international collaborative study of susceptibility testing. With cephalothin and ampicillin, groups 1 (susceptible) and 2 (moderately susceptible) were susceptible by the disk test, and with benzyl penicillin, similar results were observed when the interpretive zone standards were changed. Strains categorized as group 4 (very resistant) were resistant by the disk method, but group 3 (moderately resistant) strains were not adequately distinguished by disk testing. Group 3 susceptibility to benzyl and phenoxymethyl penicillins can be predicted by extrapolating results from tests with ampicillin disks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202343"} {"pmid": "4202345", "title": "Rearing infant rhesus together.", "content": "Rearing infant rhesus together.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202345"} {"pmid": "4202346", "title": "International symposium on gonorrhea.", "content": "International symposium on gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202346"} {"pmid": "4202347", "title": "The in vitro inhibition of growth of intracellular Listeria monocytogenes by lymphocyte products.", "content": "The in vitro inhibition of growth of intracellular Listeria monocytogenes by lymphocyte products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202347"} {"pmid": "4202348", "title": "The occurrence of 2-hydroxybutyric acid in urine from patients with lactic acidosis.", "content": "The occurrence of 2-hydroxybutyric acid in urine from patients with lactic acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202348"} {"pmid": "4202349", "title": "Serum alpha 2-macroglobulin levels in normal Chinese.", "content": "Serum alpha 2-macroglobulin levels in normal Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202349"} {"pmid": "4202352", "title": "Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C42 sites.", "content": "Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C42 sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202352"} {"pmid": "4202353", "title": "Immunoglobulins in the intestinal content of the human fetus with special reference to IgA.", "content": "Immunoglobulins in the intestinal content of the human fetus with special reference to IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202353"} {"pmid": "4202354", "title": "Isolation of F(c)5mu and Fabmu fragments of human IgM.", "content": "Isolation of F(c)5mu and Fabmu fragments of human IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202354"} {"pmid": "4202355", "title": "Effects of nalidixic acid, chloramphenicol, cycloheximide, and anisomycin on structure and development of plastids and mitochondria in greening Euglena gracilis.", "content": "Effects of nalidixic acid, chloramphenicol, cycloheximide, and anisomycin on structure and development of plastids and mitochondria in greening Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202355"} {"pmid": "4202356", "title": "Immunochemical quantitation of enzymes in human diploid cell line WI-38.", "content": "Immunochemical quantitation of enzymes in human diploid cell line WI-38.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202356"} {"pmid": "4202357", "title": "3H-colcicine binding. Failure to detect any binding to soluble proteins from various lower organisms.", "content": "3H-colcicine binding. Failure to detect any binding to soluble proteins from various lower organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202357"} {"pmid": "4202358", "title": "A cycloheximide-resistant mutant of Tetrahymena pyriformis.", "content": "A cycloheximide-resistant mutant of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202358"} {"pmid": "4202359", "title": "Antibody-mediated internalization of B lymphocyte surface membrane immunoglobulin.", "content": "Antibody-mediated internalization of B lymphocyte surface membrane immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202359"} {"pmid": "4202360", "title": "Effects of epididymal maturation, zinc (II) and copper (II) on the reactive sulfhydryl content of structural elements in rat spermatozoa.", "content": "Effects of epididymal maturation, zinc (II) and copper (II) on the reactive sulfhydryl content of structural elements in rat spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202360"} {"pmid": "4202361", "title": "Effect of inhibitors of RNA and protein synthesis on the aldosterone Na+ transport response in toad bladder.", "content": "Effect of inhibitors of RNA and protein synthesis on the aldosterone Na+ transport response in toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202361"} {"pmid": "4202362", "title": "The peritoneal fluid cytology of the adult female Rhesus monkey.", "content": "The peritoneal fluid cytology of the adult female Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202362"} {"pmid": "4202363", "title": "Aflatoxin production in some varieties of soybeans (Glycine max L.).", "content": "Aflatoxin production in some varieties of soybeans (Glycine max L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202363"} {"pmid": "4202364", "title": "Studies on carrageenan and large-bowel ulceration in mammals.", "content": "Studies on carrageenan and large-bowel ulceration in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202364"} {"pmid": "4202365", "title": "Intestinal effects of carrageenans in the rhesus monkey (Macaca mulatta).", "content": "Intestinal effects of carrageenans in the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202365"} {"pmid": "4202366", "title": "Excretion and metabolism of orally administered aflatoxin B1 by rhesus monkeys.", "content": "Excretion and metabolism of orally administered aflatoxin B1 by rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202366"} {"pmid": "4202367", "title": "Panendoscopy in the early diagnosis of acute upper gastrointestinal bleeding.", "content": "Panendoscopy in the early diagnosis of acute upper gastrointestinal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202367"} {"pmid": "4202368", "title": "Total parenteral nutrition at home for 23 months, without complication, and with good rehabilitation. A study of technical and metabolic features.", "content": "Total parenteral nutrition at home for 23 months, without complication, and with good rehabilitation. A study of technical and metabolic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202368"} {"pmid": "4202369", "title": "Further evidence of the inhabitation in a marginal population.", "content": "Further evidence of the inhabitation in a marginal population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202369"} {"pmid": "4202370", "title": "Chromatin fibril size in salivary gland chromosomes of Drosophila melanogaster.", "content": "Chromatin fibril size in salivary gland chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202370"} {"pmid": "4202371", "title": "Core fibrils in early mitotic prophase chromosomes of Drosophila melanogaster.", "content": "Core fibrils in early mitotic prophase chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202371"} {"pmid": "4202372", "title": "Mating behaviour and chaete number in Drosophila melanogaster.", "content": "Mating behaviour and chaete number in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202372"} {"pmid": "4202373", "title": "Polymorphism at two esterase loci in Drosophila melanogaster from northern Greece.", "content": "Polymorphism at two esterase loci in Drosophila melanogaster from northern Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202373"} {"pmid": "4202374", "title": "Response of puffing pattern to in vivo treatments with organomercurials in Drosophila melanogaster.", "content": "Response of puffing pattern to in vivo treatments with organomercurials in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202374"} {"pmid": "4202375", "title": "Degradation of immunoglobulins by lysosomal enzymes of tumors. I. Demonstration of the phenomenon using mouse tumors.", "content": "Degradation of immunoglobulins by lysosomal enzymes of tumors. I. Demonstration of the phenomenon using mouse tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202375"} {"pmid": "4202376", "title": "Heat-polymerization of human immunoglobulin G.", "content": "Heat-polymerization of human immunoglobulin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202376"} {"pmid": "4202377", "title": "Heterogeneity of the carcinoembryonic antigen.", "content": "Heterogeneity of the carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202377"} {"pmid": "4202378", "title": "Different susceptibility of subclasses of rat IgG2 to tryptic digestion.", "content": "Different susceptibility of subclasses of rat IgG2 to tryptic digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202378"} {"pmid": "4202379", "title": "Phototherapy in Rh incompatibility hyperbilirubinaemia.", "content": "Phototherapy in Rh incompatibility hyperbilirubinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202379"} {"pmid": "4202380", "title": "Nutritional status of refugees from Bangla Desh.", "content": "Nutritional status of refugees from Bangla Desh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202380"} {"pmid": "4202381", "title": "Quantitative model for the effects of stimulus frequency upon synchronization of auditory nerve discharges.", "content": "Quantitative model for the effects of stimulus frequency upon synchronization of auditory nerve discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202381"} {"pmid": "4202382", "title": "Letter: Precedence effects and auditory cells with long characteristic delays.", "content": "Letter: Precedence effects and auditory cells with long characteristic delays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202382"} {"pmid": "4202383", "title": "Letter: Total synthesis and pharmacological activities of N-substituted 3,14-dihydroxymorphinans.", "content": "Letter: Total synthesis and pharmacological activities of N-substituted 3,14-dihydroxymorphinans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202383"} {"pmid": "4202387", "title": "Experience with glibenclamide.", "content": "Experience with glibenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202387"} {"pmid": "4202386", "title": "Behavioral regulation of gravity: schedule effects under escape-avoidance procedures.", "content": "Behavioral regulation of gravity: schedule effects under escape-avoidance procedures. Squirrel monkeys were restrained in a centrifuge capsule and trained to escape and avoid increases in artificial gravity. During escape-avoidance, lever responses reduced centrifugally simulated gravity or postponed scheduled increases. The effect of variation in the interval of postponement (equal to the duration of decrease produced by escape responses) was studied under a multiple schedule of four components. Three components were gravity escape-avoidance with postponement times of 20, 40, and 60 sec. The fourth component was extinction. Each component was associated with a different auditory stimulus. Rate of responding decreased with increasing postponement time and higher mean g-levels occurred at shorter intervals of postponement. Effects of the schedule parameter on response rate and mean g-level were similar to effects of the schedule on free-operant avoidance and on titration behavior maintained by shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202386"} {"pmid": "4202388", "title": "New drugs and research: glybenclamide (Euglucon).", "content": "New drugs and research: glybenclamide (Euglucon).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202388"} {"pmid": "4202389", "title": "Appropriate placement of the chronically ill and aged. A successful approach by evaluation.", "content": "Appropriate placement of the chronically ill and aged. A successful approach by evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202389"} {"pmid": "4202391", "title": "Present knowledge of the relationship of nutrition to brain development and behavior.", "content": "Present knowledge of the relationship of nutrition to brain development and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202391"} {"pmid": "4202390", "title": "Autoimmune hemolytic anemia due to levodopa therapy.", "content": "Autoimmune hemolytic anemia due to levodopa therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202390"} {"pmid": "4202393", "title": "Open and closed treatment of burns with povidone-iodine.", "content": "Open and closed treatment of burns with povidone-iodine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202393"} {"pmid": "4202399", "title": "Snythesis of analogs of the thyrotropin releasing hormone (TRH) and bioassays for TRH- and TRH-inhibiting activities.", "content": "Snythesis of analogs of the thyrotropin releasing hormone (TRH) and bioassays for TRH- and TRH-inhibiting activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202399"} {"pmid": "4202400", "title": "Congenital cardiac diverticulum.", "content": "Congenital cardiac diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202400"} {"pmid": "4202402", "title": "Pathologic changes in baboon lung allografts. Comparison of two immunosuppression regimes.", "content": "Pathologic changes in baboon lung allografts. Comparison of two immunosuppression regimes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202402"} {"pmid": "4202401", "title": "Effects of gram negative endotoxemia on myocardial contractility in the awake primate.", "content": "Effects of gram negative endotoxemia on myocardial contractility in the awake primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202401"} {"pmid": "4202403", "title": "Intraluminal diverticulum of the duodenum.", "content": "Intraluminal diverticulum of the duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202403"} {"pmid": "4202404", "title": "The threshold and neuropathology of cerebral \"anoxic-ischemic\" cell change.", "content": "The threshold and neuropathology of cerebral \"anoxic-ischemic\" cell change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202404"} {"pmid": "4202405", "title": "Reversibility of ischemic brain damage.", "content": "Reversibility of ischemic brain damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202405"} {"pmid": "4202406", "title": "Two classes of dysergic brain abnormality and their conditions of occurrence.", "content": "Two classes of dysergic brain abnormality and their conditions of occurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202406"} {"pmid": "4202408", "title": "Antigenic properties of rat brain proteins fraction.", "content": "Antigenic properties of rat brain proteins fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202408"} {"pmid": "4202407", "title": "Experimental investigations on interactions between gentamicin and betamethasone dipropionate.", "content": "Experimental investigations on interactions between gentamicin and betamethasone dipropionate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202407"} {"pmid": "4202409", "title": "Congenital membranous stenosis of the midesophagus. A case report and literature survey.", "content": "Congenital membranous stenosis of the midesophagus. A case report and literature survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202409"} {"pmid": "4202410", "title": "A specific increase in cardiovascular reactivity related to sodium retention in DOCA-salt-treated rats.", "content": "A specific increase in cardiovascular reactivity related to sodium retention in DOCA-salt-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202410"} {"pmid": "4202414", "title": "The detection and localization of carbonic anhydrase in the rabbit cornea.", "content": "The detection and localization of carbonic anhydrase in the rabbit cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202414"} {"pmid": "4202415", "title": "Letter: Fractionation of the soluble proteins of chick lens on Sephadex column.", "content": "Letter: Fractionation of the soluble proteins of chick lens on Sephadex column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202415"} {"pmid": "4202416", "title": "Nucleus of the accessory optic tract. Light and electron microscopic study in normal monkeys and after eye enucleation.", "content": "Nucleus of the accessory optic tract. Light and electron microscopic study in normal monkeys and after eye enucleation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202416"} {"pmid": "4202417", "title": "Loss of visual control of the forelimb after interruption of cortical pathways.", "content": "Loss of visual control of the forelimb after interruption of cortical pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202417"} {"pmid": "4202418", "title": "Injury-induced long-first-interval bursts in cortical neurons.", "content": "Injury-induced long-first-interval bursts in cortical neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202418"} {"pmid": "4202419", "title": "Antiglobulins and cryoglobulins in rabbits producing homogeneous streptococcal antibodies.", "content": "Antiglobulins and cryoglobulins in rabbits producing homogeneous streptococcal antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202419"} {"pmid": "4202420", "title": "Experimental cryoglobulinaemia. Production and properties of streptococcus-induced rabbit cryoglobulins.", "content": "Experimental cryoglobulinaemia. Production and properties of streptococcus-induced rabbit cryoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202420"} {"pmid": "4202421", "title": "The serological response of the chicken to a protein antigen in multiple emulsion oil adjuvant.", "content": "The serological response of the chicken to a protein antigen in multiple emulsion oil adjuvant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202421"} {"pmid": "4202422", "title": "Modification of the enzymic activity of trypsin by intramolecular cross-links.", "content": "Modification of the enzymic activity of trypsin by intramolecular cross-links.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202422"} {"pmid": "4202423", "title": "Giant cell arteritis--the need for prolonged treatment.", "content": "Giant cell arteritis--the need for prolonged treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202423"} {"pmid": "4202427", "title": "Proceedings: Asynchronous pulsatile luteinizing hormone and follicle-stimulating hormone responses during luteinizing hormone-follicle-stimulating hormone releasing hormone and thyroid-stimulating hormone releasing hormone infusions.", "content": "Proceedings: Asynchronous pulsatile luteinizing hormone and follicle-stimulating hormone responses during luteinizing hormone-follicle-stimulating hormone releasing hormone and thyroid-stimulating hormone releasing hormone infusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202427"} {"pmid": "4202428", "title": "Proceedings: Distribution of radioimmunoassayable gastrin, secretin, pancreozymin and enteroglucagon in rat, dog, and baboon gut.", "content": "Proceedings: Distribution of radioimmunoassayable gastrin, secretin, pancreozymin and enteroglucagon in rat, dog, and baboon gut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202428"} {"pmid": "4202429", "title": "Proceedings: Prolactin release in the ewe induced by a synthetic tripeptide.", "content": "Proceedings: Prolactin release in the ewe induced by a synthetic tripeptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202429"} {"pmid": "4202431", "title": "Effects of psychoactive drugs on nonverbal communication and group social behavior of monkeys.", "content": "Effects of psychoactive drugs on nonverbal communication and group social behavior of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202431"} {"pmid": "4202433", "title": "Activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. II. Osmosensitivity of functional cell types in the supraoptic nucleus and the internuclear zone.", "content": "Activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. II. Osmosensitivity of functional cell types in the supraoptic nucleus and the internuclear zone. 1. We studied magnocellular neuroendocrine cells and non-neuroendocrine cells in the supraoptic nucleus (n.s.o.) and internuclear zone (i.n.z.) in the hypothalamus of unanaesthetized, chronically prepared monkeys. After antidromic identification, functional cell typing and sensory testing we injected solutions of varying tonicity into an implanted carotid cannula to determine osmosensitivity.2. On the basis of the anatomical location of the cells, the pattern of discharge in response to osmotic stimuli, the effect of posterior pituitary gland stimulation and the response to non-noxious arousing sensory stimuli, we divided the 101 osmosensitive cells studied into two major groups: eighty-nine (88%) ;specific' biphasic osmosensitive magnocellular neuroendocrine cells and twelve (12%) ;non-specific' monophasic osmosensitive non-neuroendocrine cells.3. ;Non-specific' non-neuroendocrine osmosensitive cells included nine (9%) cells lying in the internuclear zone (i.n.z.) and showing monophasic exictatory or inhibitory responses to both osmotic and to mildly arousing sensory stimuli. Three (3%) ;high-frequency burster' (h.f.b.) osmosensitive cells were located in the n.s.o.-t.o. (supraoptic nucleus-optic tract) junction, showed accelerated discharge to auditory, but not to light or touch stimuli, and were monophasically inhibited by osmotic stimuli.4. Thirty-three (33%) antidromically ;identified' magnocellular neuroendocrine cells in the n.s.o. and i.n.z. we classify as ;specific' biphasic osmosensitive cells on the basis of the excitatory-inhibitory response to intracarotid hypertonic sodium chloride and the lack of response to non-noxious arousing sensory stimuli. Fifty-six (55%) of the ;non-identified' magnocellular neuroendocrine cells in the n.s.o. and i.n.z. we also found to be ;specific' biphasic osmosensitive cells.5. Magnocellular neuroendocrine cells in n.s.o. and i.n.z. exhibited three functional types, ;silent' (s.), ;continuously active' (c.a.), and ;low frequency burster' (l.f.b.), all of which were osmosensitive with a ;specific' biphasic response. With osmotic loading some of the ;s.' cells tended to shift transiently to ;c.a.' firing, an occasional ;c.a.' cell burst briefly and a few ;l.f.b.' cells increased bursting for a short time (60 sec).6. We conclude that magnocellular neuroendocrine cells in n.s.o. and i.n.z. respond ;specifically' to intracarotid hypertonic sodium chloride with biphasic, excitatory-inhibitory, discharges and do not respond to mildly arousing sensory stimuli. We suggest that, under the conditions of our experiments, the three functional types of magnocellular neuroendocrine cells (s., c.a., l.f.b.), arising from a common primitive neuroendocrine cell, are randomly dispersed in n.s.o. and i.n.z., are each ;specialized' for secretion of a ;specific' neurohypophysial hormone, and are sensitive to ;specific' input connexions. Under this ;specific hormonal state' hypothesis we explain the paradoxical and uniform osmosensitivity of these three different functional cell types on the basis of a suprathreshold osmotic stimulus and a residual ;primitive' osmosensitivity. At present we are unable to say which functional magnocellular neuroendocrine cell types secrete a particular neurohypophysial hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202433"} {"pmid": "4202434", "title": "Intravascular coagulation--a source of possible error in carbon-clearance determinations.", "content": "Intravascular coagulation--a source of possible error in carbon-clearance determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202434"} {"pmid": "4202432", "title": "Activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. I. Functional cell types and their anatomical distribution in the supraoptic nucleus and the internuclear zone.", "content": "Activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. I. Functional cell types and their anatomical distribution in the supraoptic nucleus and the internuclear zone. 1. We recorded with tungsten micro-electrodes the spontaneous and evoked activity of single cells in the supraoptic nucleus (n.s.o.) and internuclear zone (i.n.z.) of trained, unanaesthetized monkeys who accepted experimental restraints and pituitary gland stimulation without anxiety.2. Of the 125 hypothalamic neurones analysed, 109 (87%) we classified as magnocellular neuroendocrine cells on the basis of the anatomical location of the cells, the pattern of spontaneous discharge, the effect of pituitary gland stimulation and the response to arousing sensory stimuli.3. Sixteen (13%) of the cells studied under identical conditions we labelled as non-neuroendocrine cells. Located in the i.n.z. and supraoptic nucleus-optic tract junction (n.s.o.-t.o.), these cells responded to arousing sensory stimuli, showed ;continuously active' (i.n.z.) and ;high-frequency burster' (n.s.o.-t.o.) patterns of discharge and were not driven by pituitary stimuli.4. Thirty-seven (30%) of the magnocellular neuroendocrine cells we describe as ;identified' because with pituitary gland stimulation we evoked antidromic potentials, mean latency 8.1 msec and mean conduction velocity 0.8 m/sec, with collision between orthodromic and antidromic potentials. Antidromic excitation of neuroendocrine cells was followed by inhibition of spontaneous discharge of cells for 80-125 msec suggesting the presence of recurrent collaterals in primate neuroendocrine cells. Seventy-two (57%) of the magnocellular neuroendocrine cells we designated as ;non-identified' because of lack of response, failure of collision or non-tested to pituitary gland stimulation. None of these mangocellular neuroendocrine cells, ;identified' or ;non-identified', responded to non-noxious arousing sensory stimuli.5. We find seventy-nine (63%) magnocellular neuroendocrine cells in the supraoptic nucleus (n.s.o.) and thirty (24%) magnocellular neuroendocrine cells in the internuclear zone (i.n.z.) with three basic patterns of spontaneous activity: ;silent' cells (s., four cells, 3%); ;low-frequency burster' cells (l.f.b., twenty-six cells, 21%); and ;continuously active' cells (c.a., seventy-nine cells, 63%).6. Twenty-six (21%) l.f.b. magnocellular neuroendocrine cells exhibited regular, repetitive, periodic firing patterns with a cycle of 17 sec, involving 5 sec of discharge at 5 spikes/sec and 12 sec of silence. The 26 spikes/burst showed no consistent pattern of serial interspike interval distribution. The burst pattern of discharge was interrupted by intracarotid osmotic stimuli but not by mildly arousing sensory stimuli or sleep-waking behaviour. Mean antidromic latencies of 7.98 msec and the anatomical distributions were the similarities exhibited by the l.f.b. and the c.a. cells.7. We conclude that the three functional types, s., c.a. and l.f.b., of the magnocellular neuroendocrine cells, are randomly distributed in the supraoptic nucleus (n.s.o.) and in the internuclear zone (i.n.z.) with each type receiving ;specific' input connexions. We suggest that these three characteristic firing patterns of magnocellular neuroendocrine cells may be related to the ;cellular' secretion of ;specific' neurohypophysial hormones and neurophysins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202432"} {"pmid": "4202435", "title": "One stage cardiac denervation without transplantation.", "content": "One stage cardiac denervation without transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202435"} {"pmid": "4202424", "title": "Ultrastructure of selected bacteria isolated from dental plaque as revealed by freeze-etching.", "content": "Ultrastructure of selected bacteria isolated from dental plaque as revealed by freeze-etching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202424"} {"pmid": "4202426", "title": "Fluoride concentration in root surfaces and alveolar bone of fluoride-immersed monkey incisors three weeks after replantation.", "content": "Fluoride concentration in root surfaces and alveolar bone of fluoride-immersed monkey incisors three weeks after replantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202426"} {"pmid": "4202425", "title": "Electron microscopic study of the effect of water jet lavage devices on dental plaque.", "content": "Electron microscopic study of the effect of water jet lavage devices on dental plaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202425"} {"pmid": "4202441", "title": "Prevention of pacemaker infections.", "content": "Prevention of pacemaker infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202441"} {"pmid": "4202442", "title": "Skeletal scintigraphy. I.", "content": "Skeletal scintigraphy. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202442"} {"pmid": "4202445", "title": "Electron and x-ray beam characteristics of the linac LMR-13.", "content": "Electron and x-ray beam characteristics of the linac LMR-13.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202445"} {"pmid": "4202444", "title": "Proceedings: Hughlings Jackson Lecture. Cortical localization and \"sensori motor processes\" at the \"middle level\" in primates.", "content": "Proceedings: Hughlings Jackson Lecture. Cortical localization and \"sensori motor processes\" at the \"middle level\" in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202444"} {"pmid": "4202446", "title": "Effect of preoperative radiotherapy on the growth of human renal carcinoma tissue in vitro.", "content": "Effect of preoperative radiotherapy on the growth of human renal carcinoma tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202446"} {"pmid": "4202449", "title": "Maximal cardiac output during exercise in patients with coronary artery disease.", "content": "Maximal cardiac output during exercise in patients with coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202449"} {"pmid": "4202450", "title": "Transferrin concentration in human amniotic fluid.", "content": "Transferrin concentration in human amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202450"} {"pmid": "4202440", "title": "The implications of hyperammonemia in rare and common disorders, including migraine.", "content": "The implications of hyperammonemia in rare and common disorders, including migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202440"} {"pmid": "4202451", "title": "Postmortem formation of giant endothelial vacuoles in Schlemm's canal of the monkey.", "content": "Postmortem formation of giant endothelial vacuoles in Schlemm's canal of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202451"} {"pmid": "4202452", "title": "Ultrastructural studies of the blood-aqueous barrier. 2. The barrier to horseradish peroxidase in primates.", "content": "Ultrastructural studies of the blood-aqueous barrier. 2. The barrier to horseradish peroxidase in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202452"} {"pmid": "4202453", "title": "Assessing the costs and benefits of anti-malaria programs: the Indian experience.", "content": "Assessing the costs and benefits of anti-malaria programs: the Indian experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202453"} {"pmid": "4202455", "title": "The Ausria test: critical evaluation of sensitivity and specificity.", "content": "The Ausria test: critical evaluation of sensitivity and specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202455"} {"pmid": "4202454", "title": "The role of red cell energy metabolism in the generation of irreversibly sickled cells in vitro.", "content": "The role of red cell energy metabolism in the generation of irreversibly sickled cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202454"} {"pmid": "4202456", "title": "Polygraphic studies of the effect of nitroglycerin in patients with ischaemic heart disease.", "content": "Polygraphic studies of the effect of nitroglycerin in patients with ischaemic heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202456"} {"pmid": "4202458", "title": "Correspondence: The quantitative determination of immunoglobulins by radial diffusion techniques.", "content": "Correspondence: The quantitative determination of immunoglobulins by radial diffusion techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202458"} {"pmid": "4202457", "title": "Immune response to a syngeneic rat tumour: evolution of serum cytotoxicity and blockade.", "content": "Immune response to a syngeneic rat tumour: evolution of serum cytotoxicity and blockade. The development of serum factors by Wistar rats during the growth of a syngeneic squamous cell carcinoma has been investigated to clarify the nature of the local lymphocyte anergy reported previously in this system. Sera from tumour bearing animals were tested for cytotoxicity against tumour cells by in vitro microassay, and their ability to inhibit cell mediated cytotoxicity was also studied. Serum cytotoxicity was first detected after 2 weeks of tumour growth, reaching a peak at 4 weeks and then declining. Inhibitory activity was found only in the sera of animals with advanced tumours. Anti-tumour antibody either in the sera or bound to tumour cells was not detected by immunofluorescence techniques. No evidence of general immunological debilitation was found, the animals showing normal immune responses to sheep erythrocytes and killed Brucella abortus organisms throughout tumour growth. Serum inhibitory factors may be responsible for the decline in anti-tumour immunoreactivity and the local lymphocyte anergy observed in tumour bearing hosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202457"} {"pmid": "4202459", "title": "Waldenstrom's macroglobulinemia presenting as a pulmonary mass.", "content": "Waldenstrom's macroglobulinemia presenting as a pulmonary mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202459"} {"pmid": "4202460", "title": "Hydroxyproline index in malnutrition.", "content": "Hydroxyproline index in malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202460"} {"pmid": "4202462", "title": "Ossifying lipofibroma of the median nerve.", "content": "Ossifying lipofibroma of the median nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202462"} {"pmid": "4202463", "title": "Immunological aspects of schistosomiasis. A review.", "content": "Immunological aspects of schistosomiasis. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202463"} {"pmid": "4202464", "title": "Further studies on Hepatitis Associated Antigen in acute hepatitis in Upper Egypt.", "content": "Further studies on Hepatitis Associated Antigen in acute hepatitis in Upper Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202464"} {"pmid": "4202468", "title": "A preliminary report on the differentiation of bloods of avian species.", "content": "A preliminary report on the differentiation of bloods of avian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202468"} {"pmid": "4202469", "title": "Editorial: Steroid induced peptic ulcer.", "content": "Editorial: Steroid induced peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202469"} {"pmid": "4202470", "title": "Studies on sperm capacitation. I. The relationship between a guinea-pig sperm-coating antigen and a sperm capacitation phenomenon.", "content": "Studies on sperm capacitation. I. The relationship between a guinea-pig sperm-coating antigen and a sperm capacitation phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202470"} {"pmid": "4202471", "title": "Proceedings: The use of drugs to elucidate the mechanism of luteolysis in the pseudopregnant rat.", "content": "Proceedings: The use of drugs to elucidate the mechanism of luteolysis in the pseudopregnant rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202471"} {"pmid": "4202473", "title": "Cancer of the gastrointestinal tract. II. Esophagus: treatment--localized and advanced.", "content": "Cancer of the gastrointestinal tract. II. Esophagus: treatment--localized and advanced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202473"} {"pmid": "4202472", "title": "Variations in glomerular ultrastructure in rat kidneys fixed by perfusion.", "content": "Variations in glomerular ultrastructure in rat kidneys fixed by perfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202472"} {"pmid": "4202474", "title": "Cancer of the gastrointestinal tract. II. Esophagus: Treatment--localized and advanced. Value of radiation therapy.", "content": "Cancer of the gastrointestinal tract. II. Esophagus: Treatment--localized and advanced. Value of radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202474"} {"pmid": "4202475", "title": "Cancer of the gastrointestinal tract. II. Esophagus: Treatment--localized and advanced. Innovations in radiation therapy.", "content": "Cancer of the gastrointestinal tract. II. Esophagus: Treatment--localized and advanced. Innovations in radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202475"} {"pmid": "4202461", "title": "Significance of serologic abnormalities in lepromatous leprosy.", "content": "Significance of serologic abnormalities in lepromatous leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202461"} {"pmid": "4202478", "title": "Problems of mutation detection in independently evolving laboratory strains.", "content": "Problems of mutation detection in independently evolving laboratory strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202478"} {"pmid": "4202479", "title": "Hypothesis of post-recombination resynthesis of gene copies.", "content": "Hypothesis of post-recombination resynthesis of gene copies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202479"} {"pmid": "4202480", "title": "Antigenic differences between isolates of swine vesicular disease virus and their relationship to Coxsackie B5 virus.", "content": "Antigenic differences between isolates of swine vesicular disease virus and their relationship to Coxsackie B5 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202480"} {"pmid": "4202481", "title": "Association of alpha-macroglobulins with lymphoid cells.", "content": "Association of alpha-macroglobulins with lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202481"} {"pmid": "4202482", "title": "An antenatal diagnosis of spina bifida in the Lewis rat.", "content": "An antenatal diagnosis of spina bifida in the Lewis rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202482"} {"pmid": "4202483", "title": "Suppression of TRH-mediated thyroidal release of 131-I by a synthetic analog.", "content": "Suppression of TRH-mediated thyroidal release of 131-I by a synthetic analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202483"} {"pmid": "4202484", "title": "The absorption of amoxycillin.", "content": "The absorption of amoxycillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202484"} {"pmid": "4202485", "title": "Time for a change?", "content": "Time for a change?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202485"} {"pmid": "4202486", "title": "The differential diagnosis of traumatic lesions of the occipito-atlanto-axial segment.", "content": "The differential diagnosis of traumatic lesions of the occipito-atlanto-axial segment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202486"} {"pmid": "4202487", "title": "Treatment of epilepsy with clonazepam (Ro 5-4023).", "content": "Treatment of epilepsy with clonazepam (Ro 5-4023).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202487"} {"pmid": "4202488", "title": "Malignant degeneration of a peripheral neurofibroma with pitfalls in angiographic diagnosis.", "content": "Malignant degeneration of a peripheral neurofibroma with pitfalls in angiographic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202488"} {"pmid": "4202490", "title": "Studies on recombination within the mouse H-2 complex. I. Three recombinants which position the Ss locus within the complex.", "content": "Studies on recombination within the mouse H-2 complex. I. Three recombinants which position the Ss locus within the complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202490"} {"pmid": "4202491", "title": "Raising leucocyte alloantisera in limited populations of sub-human primates.", "content": "Raising leucocyte alloantisera in limited populations of sub-human primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202491"} {"pmid": "4202493", "title": "A comparison of vaginal tampon tests used in the eradication of brucellosis.", "content": "A comparison of vaginal tampon tests used in the eradication of brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202493"} {"pmid": "4202494", "title": "Brucellosis in bulls.", "content": "Brucellosis in bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202494"} {"pmid": "4202495", "title": "Metabolism of 6-chloro-9 beta, 10 alpha-pregna-1,4,6-triene-3,20-dione in rat, rabbit, monkey and man.", "content": "Metabolism of 6-chloro-9 beta, 10 alpha-pregna-1,4,6-triene-3,20-dione in rat, rabbit, monkey and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202495"} {"pmid": "4202497", "title": "Sluice flow in placenta: maternal vascular pressure effects on fetal circulation.", "content": "Sluice flow in placenta: maternal vascular pressure effects on fetal circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202497"} {"pmid": "4202498", "title": "Serum IgG, IgM, and IgA levels in ankylosing spondylitis.", "content": "Serum IgG, IgM, and IgA levels in ankylosing spondylitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202498"} {"pmid": "4202500", "title": "Studies on the transcobalamins.", "content": "Studies on the transcobalamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202500"} {"pmid": "4202502", "title": "Enhanced plasma thyrotrophin response to thyrotrophin-releasing hormone following oestradiol administration in man.", "content": "Enhanced plasma thyrotrophin response to thyrotrophin-releasing hormone following oestradiol administration in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202502"} {"pmid": "4202501", "title": "Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice.", "content": "Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202501"} {"pmid": "4202503", "title": "Serum thyrotrophin response to thyrotrophin-releasing hormone in normal children and in patients with short stature and various endocrine or genetic diseases.", "content": "Serum thyrotrophin response to thyrotrophin-releasing hormone in normal children and in patients with short stature and various endocrine or genetic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202503"} {"pmid": "4202504", "title": "The effect of thyrotrophin-releasing hormone on plasma prolactin and thyrotrophin levels in primary hypothyroidism.", "content": "The effect of thyrotrophin-releasing hormone on plasma prolactin and thyrotrophin levels in primary hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202504"} {"pmid": "4202506", "title": "Genetic marker systems in arctic populations VII. Genetic variation in serum lipoproteins in Icelanders.", "content": "Genetic marker systems in arctic populations VII. Genetic variation in serum lipoproteins in Icelanders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202506"} {"pmid": "4202507", "title": "Phenotypic bioassay of five tribes of Orissa, India.", "content": "Phenotypic bioassay of five tribes of Orissa, India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202507"} {"pmid": "4202508", "title": "Ag (x,y,a1,z,t) antigens in Australian and New Guinea populations.", "content": "Ag (x,y,a1,z,t) antigens in Australian and New Guinea populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202508"} {"pmid": "4202511", "title": "Further experiments on the role of the nucleolus in the transfer of RNA from nucleus to cytoplasm.", "content": "Further experiments on the role of the nucleolus in the transfer of RNA from nucleus to cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202511"} {"pmid": "4202512", "title": "Electron-microscopic observations on the macronuclear development of Stylonychia mytilus and Tetrahymena pyriformis (Ciliophora-Protozoa).", "content": "Electron-microscopic observations on the macronuclear development of Stylonychia mytilus and Tetrahymena pyriformis (Ciliophora-Protozoa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202512"} {"pmid": "4202513", "title": "Contrasting incidence of Rocky Mountain spotted fever in ticks infesting wild birds in eastern U.S. Piedmont and coastal areas, with notes on the ecology of these ticks.", "content": "Contrasting incidence of Rocky Mountain spotted fever in ticks infesting wild birds in eastern U.S. Piedmont and coastal areas, with notes on the ecology of these ticks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202513"} {"pmid": "4202514", "title": "Tuberculous cervical lymphadenitis (scrofula).", "content": "Tuberculous cervical lymphadenitis (scrofula).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202514"} {"pmid": "4202505", "title": "A specific effect of mimosine on melanoma cells.", "content": "A specific effect of mimosine on melanoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202505"} {"pmid": "4202515", "title": "Activity and some properties of an acid proteinase from normal and Plasmodium berghei-infected red cells.", "content": "Activity and some properties of an acid proteinase from normal and Plasmodium berghei-infected red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202515"} {"pmid": "4202516", "title": "Antigenicity of fractions of a somatic antigen of Trypanosoma cruzi.", "content": "Antigenicity of fractions of a somatic antigen of Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202516"} {"pmid": "4202517", "title": "Hematological changes in white-tailed deer fawns, Odocoileus virgianianus, infested with Theileria-infected lone star ticks.", "content": "Hematological changes in white-tailed deer fawns, Odocoileus virgianianus, infested with Theileria-infected lone star ticks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202517"} {"pmid": "4202518", "title": "Development of Sarcocystis fusiformis in calves infected with sporocysts from dogs.", "content": "Development of Sarcocystis fusiformis in calves infected with sporocysts from dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202518"} {"pmid": "4202519", "title": "Asymptomatic gonorrhea in men. Diagnosis, natural course, prevalence and significance.", "content": "Asymptomatic gonorrhea in men. Diagnosis, natural course, prevalence and significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202519"} {"pmid": "4202509", "title": "Studies on the cultivation of mammalian cell lines in a serum-free, chemically defined medium.", "content": "Studies on the cultivation of mammalian cell lines in a serum-free, chemically defined medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202509"} {"pmid": "4202520", "title": "Fatty liver, alcoholic hepatitis and cirrhosis produced by alcohol in primates.", "content": "Fatty liver, alcoholic hepatitis and cirrhosis produced by alcohol in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202520"} {"pmid": "4202521", "title": "The new national health spending policy.", "content": "The new national health spending policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202521"} {"pmid": "4202522", "title": "Meningococcal pericarditis without meningitis presenting as tamponade.", "content": "Meningococcal pericarditis without meningitis presenting as tamponade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202522"} {"pmid": "4202523", "title": "Letter: Tumor-associated antigen in human meningioma.", "content": "Letter: Tumor-associated antigen in human meningioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202523"} {"pmid": "4202510", "title": "Characteristics of Herpesvirus saimiri-induced lymphoma cells in tissue culture.", "content": "Characteristics of Herpesvirus saimiri-induced lymphoma cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202510"} {"pmid": "4202527", "title": "The structure of the chicken egg shell and shell membranes as studied with the scanning electron microscope and energy dispersive x-ray microanalysis.", "content": "The structure of the chicken egg shell and shell membranes as studied with the scanning electron microscope and energy dispersive x-ray microanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202527"} {"pmid": "4202526", "title": "Interaction of H+ and Ca++ in the regulation of local pial vascular resistance.", "content": "Interaction of H+ and Ca++ in the regulation of local pial vascular resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202526"} {"pmid": "4202528", "title": "Parameters of infection in chicks exposed to Marek's disease by two different methods.", "content": "Parameters of infection in chicks exposed to Marek's disease by two different methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202528"} {"pmid": "4202529", "title": "The use of the chromium complex of ethylenediaminetetra-acetic acid for studies of digestion in sheep.", "content": "The use of the chromium complex of ethylenediaminetetra-acetic acid for studies of digestion in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202529"} {"pmid": "4202530", "title": "Some effects of diet with oral contraceptives on carbohydrate:lipid metabolism in the baboon.", "content": "Some effects of diet with oral contraceptives on carbohydrate:lipid metabolism in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202530"} {"pmid": "4202531", "title": "Biochemical characteristics of different forms of protein-energy malnutrition in rats.", "content": "Biochemical characteristics of different forms of protein-energy malnutrition in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202531"} {"pmid": "4202532", "title": "Plasma amino acid concentrations and ratios in different forms of protein-energy malnutrition in rats.", "content": "Plasma amino acid concentrations and ratios in different forms of protein-energy malnutrition in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202532"} {"pmid": "4202533", "title": "Abnormal behavior in non-isolate-reared rhesus monkeys.", "content": "Abnormal behavior in non-isolate-reared rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202533"} {"pmid": "4202534", "title": "3 methoxytyramine: a possible endogenous toxin of psychosis?", "content": "3 methoxytyramine: a possible endogenous toxin of psychosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202534"} {"pmid": "4202536", "title": "Folate studies in underprivileged children with epilepsy.", "content": "Folate studies in underprivileged children with epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202536"} {"pmid": "4202538", "title": "Pseudomonas aeruginosa cervical diskitis with chondro-osteomyelitis in an intravenous drug abuser.", "content": "Pseudomonas aeruginosa cervical diskitis with chondro-osteomyelitis in an intravenous drug abuser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202538"} {"pmid": "4202539", "title": "Summary of recent abstracts. IV. Trypanosomiasis.", "content": "Summary of recent abstracts. IV. Trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202539"} {"pmid": "4202540", "title": "A case of generalised avian tuberculosis in a horse.", "content": "A case of generalised avian tuberculosis in a horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202540"} {"pmid": "4202541", "title": "The immuno-diffusion method for the identification of cattle vaccinated with Brucella abortus strain 45-20.", "content": "The immuno-diffusion method for the identification of cattle vaccinated with Brucella abortus strain 45-20.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202541"} {"pmid": "4202543", "title": "Determination of lidocaine in blood and tissues.", "content": "Determination of lidocaine in blood and tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202543"} {"pmid": "4202544", "title": "Betamethasone 17-valerate by aerosol in childhood asthma.", "content": "Betamethasone 17-valerate by aerosol in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202544"} {"pmid": "4202545", "title": "Thermal insulation in malnourished Jamaican children.", "content": "Thermal insulation in malnourished Jamaican children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202545"} {"pmid": "4202546", "title": "In vitro stimulation of lecithin synthesis in rat liver mitochondria and microsomes after treatment with phospholipase C.", "content": "In vitro stimulation of lecithin synthesis in rat liver mitochondria and microsomes after treatment with phospholipase C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202546"} {"pmid": "4202548", "title": "Insulin degradation. X. Identification of insulin degrading activity of rat liver plasma membrane as glutathione-insulin transhydrogenase.", "content": "Insulin degradation. X. Identification of insulin degrading activity of rat liver plasma membrane as glutathione-insulin transhydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202548"} {"pmid": "4202547", "title": "A manganese-stimulated endonuclease from Bacillus subtilis.", "content": "A manganese-stimulated endonuclease from Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202547"} {"pmid": "4202550", "title": "Involvement of the biosynthetic pathway of purine nucleotides in the repression of bacterial sporulation.", "content": "Involvement of the biosynthetic pathway of purine nucleotides in the repression of bacterial sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202550"} {"pmid": "4202549", "title": "Temperature dependent permeability changes of Bacillus subtilis and incorporation of nucleotides into DNA.", "content": "Temperature dependent permeability changes of Bacillus subtilis and incorporation of nucleotides into DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202549"} {"pmid": "4202551", "title": "A new approach to the characterization of the B and A forms of DNA by I.R. spectroscopy.", "content": "A new approach to the characterization of the B and A forms of DNA by I.R. spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202551"} {"pmid": "4202552", "title": "Differences in susceptibility to phospholipase C of free and membrane-bound phospholipids of Mycoplasma hominis.", "content": "Differences in susceptibility to phospholipase C of free and membrane-bound phospholipids of Mycoplasma hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202552"} {"pmid": "4202554", "title": "The effect of fluoride and molybdate on caries activity in monkeys (Macaca fascicularis).", "content": "The effect of fluoride and molybdate on caries activity in monkeys (Macaca fascicularis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202554"} {"pmid": "4202553", "title": "Immunologic studies on nucleic acids and their components. I. An analysis of the specificity of anti-deoxyadenylate antibodies by a membrane-binding technique.", "content": "Immunologic studies on nucleic acids and their components. I. An analysis of the specificity of anti-deoxyadenylate antibodies by a membrane-binding technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202553"} {"pmid": "4202555", "title": "The administration's program for the aged.", "content": "The administration's program for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202555"} {"pmid": "4202556", "title": "Changing life styles in housing for the aged.", "content": "Changing life styles in housing for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202556"} {"pmid": "4202557", "title": "Dietary management of renal failure in infants and children. Principles of nutritional therapy and some representative diets.", "content": "Dietary management of renal failure in infants and children. Principles of nutritional therapy and some representative diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202557"} {"pmid": "4202560", "title": "The effects of low concentrations of actinomycin D upon nucleic acid synthesis in different cell types.", "content": "The effects of low concentrations of actinomycin D upon nucleic acid synthesis in different cell types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202560"} {"pmid": "4202562", "title": "Effects of male paragonial gland secretion on sexual receptivity and courtship behaviour of female Drosophila melanogaster.", "content": "Effects of male paragonial gland secretion on sexual receptivity and courtship behaviour of female Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202562"} {"pmid": "4202563", "title": "Structure of cephalic abnormalities in Drosophila melanogaster (Diptera: Drosophilidae).", "content": "Structure of cephalic abnormalities in Drosophila melanogaster (Diptera: Drosophilidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202563"} {"pmid": "4202564", "title": "Isolation and characterization of symbiotes from the Rocky Mountain wood tick, Dermacentor andersoni.", "content": "Isolation and characterization of symbiotes from the Rocky Mountain wood tick, Dermacentor andersoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202564"} {"pmid": "4202565", "title": "Reproduction in two species of spider monkeys, Ateles fusciceps and Ateles geoffroyi.", "content": "Reproduction in two species of spider monkeys, Ateles fusciceps and Ateles geoffroyi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202565"} {"pmid": "4202567", "title": "Rho (d) immune globulin (human).", "content": "Rho (d) immune globulin (human).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202567"} {"pmid": "4202566", "title": "Human placental lactogen (HPL) levels in abnormal pregnancies.", "content": "Human placental lactogen (HPL) levels in abnormal pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202566"} {"pmid": "4202568", "title": "Scanning electron microscopy of the primate retina.", "content": "Scanning electron microscopy of the primate retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202568"} {"pmid": "4202569", "title": "Treatment of pterygia with and without thiotepa.", "content": "Treatment of pterygia with and without thiotepa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202569"} {"pmid": "4202577", "title": "Exercise tolerance and physical training of non-selected patients after myocardial infarction.", "content": "Exercise tolerance and physical training of non-selected patients after myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202577"} {"pmid": "4202578", "title": "Phenol oxidase activity in brain tissue.", "content": "Phenol oxidase activity in brain tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202578"} {"pmid": "4202579", "title": "Prostaglandins and cannabis. II. Inhibition of biosynthesis by the naturally occurring cannabinoids.", "content": "Prostaglandins and cannabis. II. Inhibition of biosynthesis by the naturally occurring cannabinoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202579"} {"pmid": "4202580", "title": "Enzyme kinetics in relation to enzyme inhibitors.", "content": "Enzyme kinetics in relation to enzyme inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202580"} {"pmid": "4202581", "title": "Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.", "content": "Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202581"} {"pmid": "4202582", "title": "The metabolism of glyceryl trinitrate by liver and blood from different species.", "content": "The metabolism of glyceryl trinitrate by liver and blood from different species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202582"} {"pmid": "4202583", "title": "In vitro inhibition of the biosynthesis of a prostaglandin by gold and silver.", "content": "In vitro inhibition of the biosynthesis of a prostaglandin by gold and silver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202583"} {"pmid": "4202600", "title": "Polyamines and polyamine-metabolizing enzyme activities in human semen.", "content": "Polyamines and polyamine-metabolizing enzyme activities in human semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202600"} {"pmid": "4202602", "title": "Chagas enteropathy.", "content": "Chagas enteropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202602"} {"pmid": "4202603", "title": "Competitive growth of Salmonella and Pseudomonads in tetrathionate enrichment broth.", "content": "Competitive growth of Salmonella and Pseudomonads in tetrathionate enrichment broth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202603"} {"pmid": "4202604", "title": "An evaluation of commercially supplied Transgrow and Amies media for the detection of Neisseria gonorrhoeae.", "content": "An evaluation of commercially supplied Transgrow and Amies media for the detection of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202604"} {"pmid": "4202605", "title": "Sensitivity of radioimmunoassay for hepatitis B antigen in diagnostic and survey work.", "content": "Sensitivity of radioimmunoassay for hepatitis B antigen in diagnostic and survey work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202605"} {"pmid": "4202606", "title": "Non-specific binding of IgG to antibody-coated red cells. (The 'Matuhasi-Ogata phenomenon').", "content": "Non-specific binding of IgG to antibody-coated red cells. (The 'Matuhasi-Ogata phenomenon').", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202606"} {"pmid": "4202607", "title": "Contralateral epididymo-orchitis after cryo-injury to the male rabbit gonad.", "content": "Contralateral epididymo-orchitis after cryo-injury to the male rabbit gonad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202607"} {"pmid": "4202608", "title": "Physiology and pharmacology of local anesthetic agents.", "content": "Physiology and pharmacology of local anesthetic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202608"} {"pmid": "4202609", "title": "Feed sources and conditions conducive to production of aflatoxin, ochratoxin, Fusarium toxins, and zearalenone.", "content": "Feed sources and conditions conducive to production of aflatoxin, ochratoxin, Fusarium toxins, and zearalenone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202609"} {"pmid": "4202610", "title": "Passage of bovine serum albumin from the mother to rabbit blastocysts. I. Passage from the circulation to uterine lumen.", "content": "Passage of bovine serum albumin from the mother to rabbit blastocysts. I. Passage from the circulation to uterine lumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202610"} {"pmid": "4202611", "title": "Passage of bovine serum albumin from the mother to rabbit blastocysts. II. Passage from uterine lumen to blastocyst fluid.", "content": "Passage of bovine serum albumin from the mother to rabbit blastocysts. II. Passage from uterine lumen to blastocyst fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202611"} {"pmid": "4202612", "title": "A note on the purification of follicle-stimulating and luteinizing hormones from baboon pituitaries.", "content": "A note on the purification of follicle-stimulating and luteinizing hormones from baboon pituitaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202612"} {"pmid": "4202614", "title": "Effects of cooling dentate nucleus on tracking-task performance in monkeys.", "content": "Effects of cooling dentate nucleus on tracking-task performance in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202614"} {"pmid": "4202613", "title": "Eye movements evoked by cerebellar stimulation in the alert monkey.", "content": "Eye movements evoked by cerebellar stimulation in the alert monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202613"} {"pmid": "4202615", "title": "Effects of cooling interposed nuclei on tracking-task performance in monkeys.", "content": "Effects of cooling interposed nuclei on tracking-task performance in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202615"} {"pmid": "4202616", "title": "Experimental comparison of radioactive agents for studies of the placenta.", "content": "Experimental comparison of radioactive agents for studies of the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202616"} {"pmid": "4202617", "title": "Cold-sensitive Pseudomonas RNA polymerase. I. Characterization of the host dependent cold-sensitive restriction of phage CB3.", "content": "Cold-sensitive Pseudomonas RNA polymerase. I. Characterization of the host dependent cold-sensitive restriction of phage CB3. Analysis of bacteriophage CB3 infection of Pseudomonas aeruginosa strain PAT2 establishes that phage induced changes in net macromolecular synthesis are absent at nonpermissive phage growth temperatures (32 C). Alterations which are evident in the PAT2 strain at 37 C or in the fully permissive strain, PAO1C, at either warm or cold temperatures do not occur in PAT2 at low temperatures. CB3 DNA synthesis and the degradation of host DNA to approximately 78S components occur at 37 C, but are absent in PAT2 at 20 C. Nevertheless, attachment of phage DNA to host cytoplasmic material occurs under permissive and nonpermissive conditions. This binding of phage DNA at 20 C is identical in nature to phage DNA bound at 37 C. Thus, the conditional cold-sensitive PAT2 host function in the growth of CB3 is expressed subsequent to membrane binding of the infecting genomes but prior to the onset of the initiation of CB3 DNA synthesis, the inhibition of host DNA synthesis, and the transient depression in RNA synthesis which occurs in permissive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202617"} {"pmid": "4202618", "title": "Cold-sensitive Pseudomonas RNA polymerase. II. Cold-promoted restriction of bacteriophage CB3 and the lack of host-dependent bacteriophage-specific RNA transcription.", "content": "Cold-sensitive Pseudomonas RNA polymerase. II. Cold-promoted restriction of bacteriophage CB3 and the lack of host-dependent bacteriophage-specific RNA transcription. Cold-sensitive restriction of Pseudomonas phage CB3 by Pseudomonas aeruginosa strain PAT2 involves some aspect of CB3 specific RNA synthesis at 20 C. Experiments using chloramphenicol treatment and RNA-DNA hybridization establish that the amount of CB3 RNA present at 20 C is consistent with the known percentage of phage yielder cells at 20 C. Thus, it appears that nonyielder cells of PAT2 synthesize little or no phage-specific mRNA. Burgess technique extracted PAT2 RNA polymerase (RNAP) is cold sensitive when assayed in vitro with CB3 DNA at 20 C. However, it is not cold sensitive when either calf thymus or PAT2 DNA are the templates for transcription. Low ionic strength assay conditions eliminate the cold sensitivity of PAT2 RNAP. The effect of low ionic environments on transcription initiation along with the in vivo and in vitro suppression of cold sensitivity by host rifampin resistance suggests that the inability of CB3 to reproduce in PAT2 at 20 C is a cold-sensitive step in host RNAP initiation. Our modified RNAP extraction procedure for PAT2 and PAO1C also results in the recovery of cold-sensitive PAT2 RNAP with respect to CB3 DNA templates and points to basic enzymological differences between the two hosts. A model is presented for the unusual influence of temperature on the initiation process of both PAT2 and PAO1C on RNAP transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202618"} {"pmid": "4202619", "title": "Antigenic properties of bacteriophage phi 29 structural proteins.", "content": "Antigenic properties of bacteriophage phi 29 structural proteins. Serological methods and electron microscopy were used to study the structural proteins of the small Bacillus subtilis bacteriophage phi29. This virus has a large number of fibers attached at both ends of its prolate head. A complex neck assembly is comprised of 12 symmetrically arranged appendages as the outer component. Head fibers, neck appendages, and the head surface bind anti-phi29 antibodies. Immune sera absorbed with defective lysates of suppressor-sensitive (sus) mutants have been used to determine the genetic control of neck appendages production. Studies on the serum-blocking power of lysates defective in different tail components showed that appendages contain the main serum-blocking protein. This finding suggests an essential role of the neck appendages in phage adsorption or DNA injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202619"} {"pmid": "4202622", "title": "Isolation of skyrin from Hypomyces iactifluorum.", "content": "Isolation of skyrin from Hypomyces iactifluorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202622"} {"pmid": "4202623", "title": "The secretion of migration inhibitory factor by intact schistosome egg granulomas maintained in vitro.", "content": "The secretion of migration inhibitory factor by intact schistosome egg granulomas maintained in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202623"} {"pmid": "4202625", "title": "A comparison of the cardiovascular actions of thalicarpine and its moieties.", "content": "A comparison of the cardiovascular actions of thalicarpine and its moieties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202625"} {"pmid": "4202629", "title": "Mechanism of action of L-asparaginase on the cell cycle and growth in acute lymphoblastic leukemia.", "content": "Mechanism of action of L-asparaginase on the cell cycle and growth in acute lymphoblastic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202629"} {"pmid": "4202630", "title": "The effect of L-asparaginase on DNA and RNA synthesis by lymphoblasts of acute lymphocytic leukemia.", "content": "The effect of L-asparaginase on DNA and RNA synthesis by lymphoblasts of acute lymphocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202630"} {"pmid": "4202624", "title": "Development of the auditory cortex of monkeys during prenatal ontogenesis.", "content": "Development of the auditory cortex of monkeys during prenatal ontogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202624"} {"pmid": "4202631", "title": "Lymphocyte surface markers in lymphoproliferative disorders.", "content": "Lymphocyte surface markers in lymphoproliferative disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202631"} {"pmid": "4202632", "title": "Binding of folic acid to serum proteins. II. The effect of diphenylhydantoin treatment and of various diseases.", "content": "Binding of folic acid to serum proteins. II. The effect of diphenylhydantoin treatment and of various diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202632"} {"pmid": "4202633", "title": "The prevalence of Australia antigen and antibody in haemophilia.", "content": "The prevalence of Australia antigen and antibody in haemophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202633"} {"pmid": "4202634", "title": "Blood group and tissue mosaicism in a Natal Indian woman.", "content": "Blood group and tissue mosaicism in a Natal Indian woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202634"} {"pmid": "4202635", "title": "Acquired factor IX deficiency. A report of two cases.", "content": "Acquired factor IX deficiency. A report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202635"} {"pmid": "4202636", "title": "Haemoglobin D Punjab in a Cuban family and its interaction with haemoglobin S.", "content": "Haemoglobin D Punjab in a Cuban family and its interaction with haemoglobin S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202636"} {"pmid": "4202637", "title": "Human simulated diving experiments at saturation under oxygen-helium exposures up to 500 meters: electroencephalographic data.", "content": "Human simulated diving experiments at saturation under oxygen-helium exposures up to 500 meters: electroencephalographic data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202637"} {"pmid": "4202638", "title": "Electron microscopic study of endothelium of stored and cryopreserved monkey corneas.", "content": "Electron microscopic study of endothelium of stored and cryopreserved monkey corneas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202638"} {"pmid": "4202639", "title": "Infection control in intravenous therapy.", "content": "Infection control in intravenous therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202639"} {"pmid": "4202640", "title": "Interference between borreliae and trypanosomes. I. Antigenic analysis, fluorescent antibody and immobilisine studies of Borrelia turicatae and Trypanosoma cruzi.", "content": "Interference between borreliae and trypanosomes. I. Antigenic analysis, fluorescent antibody and immobilisine studies of Borrelia turicatae and Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202640"} {"pmid": "4202641", "title": "Studies on the life cycle of Phaneropsolus bonnei and Prosthodendrium molenkampi in Thailand.", "content": "Studies on the life cycle of Phaneropsolus bonnei and Prosthodendrium molenkampi in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202641"} {"pmid": "4202644", "title": "Chromosomal proteins of Drosophila embryos.", "content": "Chromosomal proteins of Drosophila embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202644"} {"pmid": "4202643", "title": "Fetal hormones, the brain, and human sex differences: a heuristic, integrative review of the recent literature.", "content": "Fetal hormones, the brain, and human sex differences: a heuristic, integrative review of the recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202643"} {"pmid": "4202645", "title": "Microheterogeneity of rat liver ferritin: comparison of electrofocusing and chromatographic fractions.", "content": "Microheterogeneity of rat liver ferritin: comparison of electrofocusing and chromatographic fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202645"} {"pmid": "4202647", "title": "The binding affinities of rheumatoid factors interacting with the C gamma 3 homology region of human IgG.", "content": "The binding affinities of rheumatoid factors interacting with the C gamma 3 homology region of human IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202647"} {"pmid": "4202648", "title": "Immunological and physicochemical studies of IgA1 (delta) cryogelglobulinaemia.", "content": "Immunological and physicochemical studies of IgA1 (delta) cryogelglobulinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202648"} {"pmid": "4202649", "title": "Scoliosis.", "content": "Scoliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202649"} {"pmid": "4202651", "title": "Proceedings: The preservation of ciliated protozoa at low temperature.", "content": "Proceedings: The preservation of ciliated protozoa at low temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202651"} {"pmid": "4202650", "title": "Proceedings: Factors affecting repair of sublethal injury in frozen or freeze-dried bacteria.", "content": "Proceedings: Factors affecting repair of sublethal injury in frozen or freeze-dried bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202650"} {"pmid": "4202652", "title": "Proceedings: Freezing and freeze-drying of Spirulina platensis.", "content": "Proceedings: Freezing and freeze-drying of Spirulina platensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202652"} {"pmid": "4202655", "title": "Diagnosing thyroid disease by selected laboratory tests.", "content": "Diagnosing thyroid disease by selected laboratory tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202655"} {"pmid": "4202654", "title": "Lidoflazine: double-blind trial of a new coronary vasodilator in angina pectoris.", "content": "Lidoflazine: double-blind trial of a new coronary vasodilator in angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202654"} {"pmid": "4202657", "title": "The effects of temporary protein deprivation on bone width and bone mineral content in rhesus macaques.", "content": "The effects of temporary protein deprivation on bone width and bone mineral content in rhesus macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202657"} {"pmid": "4202658", "title": "Degradation of coxsackievirus type A9 by proteolytic enzymes.", "content": "Degradation of coxsackievirus type A9 by proteolytic enzymes. The means by which coxsackievirus type A9 (CA9) is inactivated by proteolytic enzymes was investigated. After reaction of (14)C-leucine-labeled CA9 with Pronase, free leucine was liberated as measured by radiochromatography. Treatment of (14)C-leucine-labeled CA9 with trypsin or proteolytic filtrates of Pseudomonas aeruginosa caused the release of a variety of labeled substances. The extent of viral ribonucleic acid (RNA) release after exposure of CA9 to Pronase was determined by RNA infectivity tests or trichloroacetic acid solubility tests. Infective viral RNA was found not to be consistently released by reaction of CA9 with Pronase, but further treatment with 1% sodium dodecyl sulfate at pH 7.0 promoted viral RNA release. Sodium dodecyl sulfate treatment of CA9 that had not been reacted with Pronase did not inactivate virus or cause viral RNA release. Reaction of Pronase with (32)P-labeled CA9 resulted in the liberation of virus components soluble in cold trichloroacetic acid, whereas untreated CA9 or CA9 reacted with ribonuclease were precipitated by cold trichloroacetic acid. These results demonstrate that the primary means by which protease-sensitive enteroviruses are inactivated is by degradation of the virus capsid, with subsequent release of viral RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202658"} {"pmid": "4202659", "title": "Immunocyte response to experimental mumps virus infection in Rhesus monkeys.", "content": "Immunocyte response to experimental mumps virus infection in Rhesus monkeys. Nineteen rhesus monkeys were inoculated with mumps virus by retrograde ductal instillation into the parotid gland. Evidence of infection was obtained in all instances. Virus was isolated from buccal swabbings and parotid biopsies for 1 week after inoculation. A vigorous serum-neutralizing antibody response occurred within 3 weeks, and there was marked monocytic infiltration of the parotid stroma. The monocytic infiltrate comprised as much as 60% of the total gland volume 1 week after infection. The predominant inflammatory cells were non-immunoglobulin-containing mononuclear cells resembling lymphocytes. Plasma cells containing immunoglobulin G (IgG), IgA, IgM, and IgE increased in numbers in the gland after infection, the greatest increase occurring in IgG-containing cells. Neutralizing antibodies and interferon were found in extracts prepared from the infected glands. Neutralizing activity was highest in samples taken 3 weeks after infection but was detectable in samples taken as soon as 36 to 48 h after infection. Interferon activity was detected in significant amounts 36 to 48 h after infection. Challenge of previously infected animals resulted in an increase in the monocytic infiltrate as well as an increase in numbers of immunoglobulin-containing plasma cells. However, reinfection did not occur as evidenced by the inability to culture shed virus after challenge. This model should be useful for in vivo study of biochemical mediators which evoke inflammatory cell infiltration and which may be significant both in protection and in tissue damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202659"} {"pmid": "4202660", "title": "Mechanism of Shope fibroma virus-induced suppression of host deoxyribonucleic acid synthesis.", "content": "Mechanism of Shope fibroma virus-induced suppression of host deoxyribonucleic acid synthesis. The effects of treatment with live or inactivated Shope fibroma virus on host cell deoxyribonucleic acid (DNA) synthesis were determined. The incorporation of (3)H-thymidine into nuclear DNA was suppressed by both active and inactivated virus, although live virus was more effective. During the early phase of infection, stimulation of host nuclear DNA synthesis of up to 240% of control value was observed in cells infected with active virus. Inhibition of DNA synthesis began at about the 8th h and was maximal by 12 h postinfection. Virus inactivated by ultraviolet-irradiation or heat treatment did not induce viral DNA synthesis but was, nevertheless, able to suppress host DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202660"} {"pmid": "4202661", "title": "Rickettsial hemolysis: effect of metabolic inhibitors upon hemolysis and adsorption.", "content": "Rickettsial hemolysis: effect of metabolic inhibitors upon hemolysis and adsorption. The hemolysis of sheep red blood cells by typhus rickettsiae is initiated by a temperature-sensitive adsorption process that is dependent on the energy-generating metabolism of the rickettsaie but not that of the erythrocyte. Adsorption is followed by events dependent on the metabolism of both the rickettsaie and red blood cells. At 34 C the adsorption step is complete after about 4 min, at lower temperatures the time required for adsorption is increased. At 0 C no adsorption occurred. The addition of cyanide inhibited the catabolism of glutamate by the rickettsiae and, consequently, both adsorption and the subsequent steps in hemolysis. The starvation of the rickettsiae for glutamate also prevented adsorption. Fluoride had no demonstrable effect on rickettsial metabolism nor the adsorption step but inhibited glycolysis in the erythrocytes and the hemolysis of the erythrocytes by rickettsiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202661"} {"pmid": "4202662", "title": "Unique teichoic acid isolated from the cell walls of a strain of Staphylococcus aureus.", "content": "Unique teichoic acid isolated from the cell walls of a strain of Staphylococcus aureus. Teichoic acid antigen extracted from cell walls of a strain of Staphylococcus aureus has been shown to have the unique structure of glycerolphosphate, with N-acetyl-d-galactosamine as the immunodominant substituent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202662"} {"pmid": "4202663", "title": "Antibody response to chlamydia agents: lack of immunoglobulin M antibodies during the secondary immune response.", "content": "Antibody response to chlamydia agents: lack of immunoglobulin M antibodies during the secondary immune response. Intramuscular inoculation of the monkey with a massive dose of Chlamydia agent particles resulted in the production of high levels of immunoglobulin M antibodies. These antibodies were broadly specific and reacted to high titers with heterologous antigens. Challenge inoculation of the same monkeys with heterologous Chlamydia agent particles resulted in the production of increased levels of immunoglobulin G but not immunoglobulin M antibodies. Some immunological implications of these results are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202663"} {"pmid": "4202664", "title": "Effects of endotoxin on gluconeogenesis, glycogen synthesis, and liver glycogen synthase in mice.", "content": "Effects of endotoxin on gluconeogenesis, glycogen synthesis, and liver glycogen synthase in mice. This study was undertaken to characterize the nature of carbohydrate loss due to endotoxin poisoning in mice and to elucidate mechanisms responsible for the changes. Female ICR mice, fasted overnight, were injected intraperitoneally with a mean lethal dose of endotoxin extracted from Salmonella typhimurium strain SR-11. Liver glycogen levels, alanine-U-(14)C and pyruvate-2-(14)C incorporation into blood glucose and liver glycogen, glucose-U-(14)C incorporation into liver glycogen, and liver glycogen synthase activities were measured at intervals after treatment. Liver glycogen in fasted mice given endotoxin was diminished significantly as early as 1 h after treatment. Liver glycogen synthase was significantly decreased in poisoned mice at 17 h. The use of actinomycin D showed that the induction of this enzyme due to fasting or hydrocortisone, or both, was inhibited by endotoxin. The incorporation of the (14)C-label from alanine-U-(14)C, pyruvate-2-(14)C, or glucose-U-(14)C into blood glucose and liver glycogen was substantially impaired in endotoxemic animals at 12 h. Decreases in incorporation occurred as early as 4 h after treatment. The progressive increase in glycogen synthase activity observed in fasted controls was not seen in endotoxin-poisoned mice. The administration of a glucose or pyruvate load to endotoxin-treated mice did not restore gluconeogenesis, glycogen synthesis, or liver glycogen synthase activity to normal levels. The in vivo activation of glycogen synthase by glucose was significantly reduced in endotoxemic animals. These changes indicate reduced carbohydrate synthesis as a probable cause for rapid sugar loss during endotoxemia in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202664"} {"pmid": "4202665", "title": "Gel precipitation of common enterobacterial antigen by its antibody.", "content": "Gel precipitation of common enterobacterial antigen by its antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202665"} {"pmid": "4202666", "title": "Observations on the cross-immunity between Theileria lawrencei (Serengeti) and Theileria parva (Muguga) in cattle.", "content": "Observations on the cross-immunity between Theileria lawrencei (Serengeti) and Theileria parva (Muguga) in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202666"} {"pmid": "4202667", "title": "Anoxic radiosensitization of two Bacillus species by p-nitroacetophenone.", "content": "Anoxic radiosensitization of two Bacillus species by p-nitroacetophenone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202667"} {"pmid": "4202668", "title": "Influence of cysteamine on intramolecular energy transfer in 5-bromouracil-substituted phage-DNA.", "content": "Influence of cysteamine on intramolecular energy transfer in 5-bromouracil-substituted phage-DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202668"} {"pmid": "4202669", "title": "Phagocytic and bacterial properties of normal human monocytes.", "content": "Phagocytic and bacterial properties of normal human monocytes. The bactericidal and phagocytic capacities of monocytes for E. coli, Staphylococcus, Salmonella, and Listeria, and factors that influence these functions were evaluated and compared with those of the polymorphonuclear leukocytes of 30 normal human subjects. Monocytes killed a significantly smaller proportion of each of the bacterial species than did neutrophils from the same individuals. Whereas the neutrophils of all individuals demonstrated the ability to kill significant numbers of the four bacterial species, there was a marked variation in the effect of monocytes of different individuals on the growth curves of these same bacteria. When the bactericidal capacity of an individual's monocytes to more than one species of bacteria was examined in the same experiment, a significant difference in the effect of monocytes on the growth curve of one bacterial species as opposed to another was noted in 4 of 17 subjects. The bactericidal ability of monocytes of single individuals was consistent on different days in 9 of the 11 subjects whose monocytes were examined more than once against the same bacteria. Studies were performed to determine if the lesser bactericidal capability of monocytes was due to a difference in the ability of monocytes and neutrophils to phagocytize or to a difference in the ability of these cells to kill ingested bacteria or both. The results demonstrated that monocytes phagocytize bacteria significantly less well than neutrophils, but the intracellular killing capacity of both cell types is equal. Addition of phenylbutazone to cell suspensions completely inhibited intracellular killing by both monocytes and neutrophils, suggesting the possibility that the bactericidal mechanisms in both cell types might be similar. Monocyte killing of E. coli, Salmonella, and Listeria, but not of Staphylococcus, was significantly diminished in heat-inactivated autologous serum. Neither increasing the concentration of autologous serum from 10% to 25% nor replacement of autologous serum with pooled human serum had any effect on monocyte killing of any of the four bacteria. These studies demonstrate that peripheral blood monocytes are less bactericidal for the four bacterial species than neutrophils, solely because monocytes are less phagocytic. A baseline for further study of factors that influence monocyte function and for study of this cell in selected patient populations is provided.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202669"} {"pmid": "4202670", "title": "Studies on derivation of transcobalamin 3 from granulocytes. Enhancement by lithium and elimination by fluoride of in vitro increments in vitamin B12-binding capacity.", "content": "Studies on derivation of transcobalamin 3 from granulocytes. Enhancement by lithium and elimination by fluoride of in vitro increments in vitamin B12-binding capacity. Unsaturated vitamin B(12)-binding capacity (UBBC) of human serum is not reproducibly measurable because it increases variably in vitro in relation to time, temperature, and, in the case of plasma, anticoagulant present before removal of cells. This variable increase proved to be due to variable release in vitro of transcobalamin III (TC III) from granulocytes. UBBC increase was greatest (up to fourfold normal levels) in the presence of lithium, which is the heparin salt used in many laboratories doing UBBC studies. In vitro increase was least when blood was collected in EDTA at 0 degrees C and immediately centrifuges at 0 degrees C (T(0) sample); results equivalent to T(0) were obtained at room temperature even after several hours delay when 47 mM fluoride was present; either cold temperature or 47 mM fluoride appeared to prevent TC III release from granulocytes. The measured levels of the three transcobalamins with T(0) methods of collection, which presumably reflect most closely the in vivo circulating levels, suggest that TC I and TC III in normal plasms are of the same order of magnitude and together normally comprise less than 10% of the UBBC. Approximately 90% of the UBBC content of sonicates of peripheral blood granulocytes and of bone marrow aspirates of normal individuals appears to be TC III, with the rest being TC I. Thus, normal myelocytes, like normal granulocytes, appear to contain mainly TC III. No TC II was present in any of the sonicates. The general practice in most laboratories has been to determine serum UBBC. Because in vitro increments of up to 119% were found to occur in serum, this practice should be replaced by collection using methods that prevent such increments. Blood collected in EDTA-47 mM NaF had a stable, reproducible UBBC with no significant in vitro increment with time.EDTA-NaF UBBC was 640+/-168 (range 380-921 pg B(12) bound/ml plasma) for 12 normal adult men and 809+/-232 (range 505-1208) for normal adult women. It presumably approximates circulating UBBC and is substantially below the serum UBBC mean of 935+/-262 (range 611-1506 for the same 12 men) and 1273+/-355 (range 811-2306 for the same 10 women).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202670"} {"pmid": "4202671", "title": "Enzymatically inactive red cell carbonic anhydrase B in a family with renal tubular acidosis.", "content": "Enzymatically inactive red cell carbonic anhydrase B in a family with renal tubular acidosis. An inactive mutant form of red cell carbonic anhydrase B is described in three members of a large kindred who manifest infantile renal tubular acidosis and nerve deafness. A combination of enzymatic and immunologic investigations permitted its detection, despite the fact that both antigenic and electrophoretic properties of the mutant were identical to those of the normal form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202671"} {"pmid": "4202673", "title": "Direct radiochemical assay for serum folate: competition between 3H-folic acid and 5-methyltetrahydrofolic acid for a folate binder.", "content": "Direct radiochemical assay for serum folate: competition between 3H-folic acid and 5-methyltetrahydrofolic acid for a folate binder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202673"} {"pmid": "4202672", "title": "Antibiotic levels in pericardial fluid.", "content": "Antibiotic levels in pericardial fluid. An experimental model was designed to study the ability of antibiotics to enter the pericardial compartment. Noninfected and infected pericardial fluid and serum antibiotic activities were determined in adult mongrel dogs before and at intervals after antibiotic administration. After the administration of penicillin G, methicillin, cephaloridine, streptomycin, or gentamicin, clinically adequate antibiotic levels in the noninfected pericardial fluid were obtained within 1 h, and these levels approached or exceeded the serum levels within 2-4 h. Antibiotic levels obtained from infected dog pericardial fluids were higher than those from noninfected animals. Patients' serum and pericardial fluid antibiotic levels were measured after penicillin G, penicillin V, cephalothin, and gentamicin administration. We have found, both in the canine and human studies, that pericardial antibiotic levels taken at least 2 h after antibiotic administration are almost identical to those in the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202672"} {"pmid": "4202674", "title": "Hepatic bilirubin glucuronidation in neonates with unconjugated hyperbilirubinemia and congenital gastrointestinal obstruction.", "content": "Hepatic bilirubin glucuronidation in neonates with unconjugated hyperbilirubinemia and congenital gastrointestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202674"} {"pmid": "4202675", "title": "The role of medical education in planning the development of a national health care system.", "content": "The role of medical education in planning the development of a national health care system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202675"} {"pmid": "4202676", "title": "Some good features of the British National Health Service.", "content": "Some good features of the British National Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202676"} {"pmid": "4202677", "title": "The world of health and the American physician.", "content": "The world of health and the American physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202677"} {"pmid": "4202678", "title": "Supervoltage isocentric arc therapy in carcinoma of the bladder.", "content": "Supervoltage isocentric arc therapy in carcinoma of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202678"} {"pmid": "4202679", "title": "Paper chromatographic determination of tetracycline.", "content": "Paper chromatographic determination of tetracycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202679"} {"pmid": "4202680", "title": "Nitroglycerin sublingual tablets. II. Preparation and stability of a new, stabilized, sublingual, molded nitroglycerin tablet.", "content": "Nitroglycerin sublingual tablets. II. Preparation and stability of a new, stabilized, sublingual, molded nitroglycerin tablet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202680"} {"pmid": "4202681", "title": "Synthesis and biological activity of quinolyl acetic acid derivatives.", "content": "Synthesis and biological activity of quinolyl acetic acid derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202681"} {"pmid": "4202682", "title": "Enhancement of benzalkonium chloride and chlorhexidine acetate activity against Pseudomonas aeruginosa by aromatic alcohols.", "content": "Enhancement of benzalkonium chloride and chlorhexidine acetate activity against Pseudomonas aeruginosa by aromatic alcohols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202682"} {"pmid": "4202684", "title": "Optimal criteria for care of patients with cancer.", "content": "Optimal criteria for care of patients with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202684"} {"pmid": "4202683", "title": "Gram-negative infections in cancer. Study of empiric therapy comparing carbenicillin-cephalothin with and without gentamicin.", "content": "Gram-negative infections in cancer. Study of empiric therapy comparing carbenicillin-cephalothin with and without gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202683"} {"pmid": "4202685", "title": "Pneumonia caused by Neisseria meningitidis.", "content": "Pneumonia caused by Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202685"} {"pmid": "4202688", "title": "Serum proteins and gestational age.", "content": "Serum proteins and gestational age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202688"} {"pmid": "4202689", "title": "Neutron radiographic examination of soft-and hard-tissue structures of the oral cavity.", "content": "Neutron radiographic examination of soft-and hard-tissue structures of the oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202689"} {"pmid": "4202690", "title": "Research in neurosis: a selective review. 1. Causes and courses.", "content": "Research in neurosis: a selective review. 1. Causes and courses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202690"} {"pmid": "4202691", "title": "On the mechanism by which bovine fibrinogen induces the release and availability reaction of human blood platelets.", "content": "On the mechanism by which bovine fibrinogen induces the release and availability reaction of human blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202691"} {"pmid": "4202692", "title": "Immunological studies on Egyptian polyvalent antivenins.", "content": "Immunological studies on Egyptian polyvalent antivenins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202692"} {"pmid": "4202693", "title": "Phospholipase isoenzymes from Naja naja venom. I. Purification and partial characterization.", "content": "Phospholipase isoenzymes from Naja naja venom. I. Purification and partial characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202693"} {"pmid": "4202694", "title": "Antiendotoxin effect of disodium cromoglycate.", "content": "Antiendotoxin effect of disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202694"} {"pmid": "4202696", "title": "Blood parasites of the Impala (Aepyceros melampus) in the Serengeti National Park.", "content": "Blood parasites of the Impala (Aepyceros melampus) in the Serengeti National Park.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202696"} {"pmid": "4202687", "title": "PCB residues in plankton from the Gulf of St Lawrence.", "content": "PCB residues in plankton from the Gulf of St Lawrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202687"} {"pmid": "4202697", "title": "Distribution and persistence of polychlorinated biphenyls (Aroclor 1254) in growing piglets.", "content": "Distribution and persistence of polychlorinated biphenyls (Aroclor 1254) in growing piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202697"} {"pmid": "4202700", "title": "Congenital defects of the corpus callosum. Morphology and encephalographic appearances.", "content": "Congenital defects of the corpus callosum. Morphology and encephalographic appearances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202700"} {"pmid": "4202699", "title": "A clinical study of the benzodiazepine Ro 5-4023 (clonazepam) in the treatment of epilepsy.", "content": "A clinical study of the benzodiazepine Ro 5-4023 (clonazepam) in the treatment of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202699"} {"pmid": "4202701", "title": "Drug susceptibility-resistance pattern of gram-negative uropathogens to seven cephalosporins.", "content": "Drug susceptibility-resistance pattern of gram-negative uropathogens to seven cephalosporins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202701"} {"pmid": "4202702", "title": "Analytical methodology for bioactive compounds. Photochemically assisted analysis of chlorinated hydrocarbon pesticides in the presence of polychlorinated biphenyls.", "content": "Analytical methodology for bioactive compounds. Photochemically assisted analysis of chlorinated hydrocarbon pesticides in the presence of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202702"} {"pmid": "4202703", "title": "Microdilution antibiotic susceptibility test: examination of certain variables.", "content": "Microdilution antibiotic susceptibility test: examination of certain variables. A semiautomated microdilution susceptibility test is described. The effect of certain parameters such as inoculum size, growth media, incubation conditions, and inoculum dispensing systems was studied. Both medium type and inoculum size caused significant variations in the minimum inhibitory concentrations (MIC) of certain antibiotic-organism combinations. No effect on MIC was observed as a function of incubator type. Efforts to read a reproducible MIC value in less than 12 h failed. A commercially available wire pronged inoculator was determined to be inaccurate and unsafe. Disposable dropper pipettes proved to be economical, accurate, and precise. Although a standard method for microdilution antibiotic susceptibility testing is not proposed, data are presented which show that future attempts at standardized procedures are mandatory if inter- and intralaboratory reliability is desired.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202703"} {"pmid": "4202704", "title": "Development and evaluation of a direct fluorescent antibody method for the diagnosis of Pneumocystis carinii infections in experimental animals.", "content": "Development and evaluation of a direct fluorescent antibody method for the diagnosis of Pneumocystis carinii infections in experimental animals. Because no fully satisfactory diagnostic method has been available for use in pneumocystis infection, an attempt was made to apply the fluorescent antibody technique in the identification of Pneumocystis carinii. Hyperimmune sera were prepared in rabbits against P. carinii from human and rat sources. After proper adsorption, these antisera were conjugated with fluorescein isothiocyanate and used as reagents in a direct fluorescent antibody procedure. Each of the two reagents was found to stain trypsin-treated P. carinii organisms from either human or rat sources, indicating the presence of common antigens. Stained organisms were demonstrated in the hypopharyngeal material from rats in which pneumocystis infection had been activated by the administration of corticosteroid. From the results reported here, the procedure outlined is considered sufficiently sensitive and specific to justify tests on pneumocystis infections in man. The findings in a series of specimens from human subjects will be reported separately. The method also provides an extended approach to related research problems. The need for controls of the procedure at all points is emphasized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202704"} {"pmid": "4202705", "title": "Method for the selective enumeration of blue-green bacteria in water.", "content": "Method for the selective enumeration of blue-green bacteria in water. A membrane filter method for the selective enumeration of blue-green bacteria has been developed which, on the basis of studies with laboratory cultures and field tests, has proved to be both practical and reproducible. The filters are incubated under specified conditions of temperature and illumination on a mineral salts agar medium supplemented with yeast extract and containing cycloheximide to eliminate eukaryotic contaminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202705"} {"pmid": "4202706", "title": "Effects of changes in feed level, starvation, and level of feed after starvation upon the concentration of rumen protozoa in the ovine.", "content": "Effects of changes in feed level, starvation, and level of feed after starvation upon the concentration of rumen protozoa in the ovine. Four rumen fistulated sheep were used in five experiments to investigate the effect of feed level upon the concentration of rumen ciliate protozoa. The sheep were fed once daily 650 g of a pelleted diet composed of corn cobs, 45%; alfalfa meal, 35%; oats, 12.5%; cane molasses, 5%; urea, 0.4%; and vitamins and minerals, 2%. The concentration of protozoa reached minimum and maximum values at 5 and 22.5 h after feeding, respectively. Thus, to estimate apparent generation rates, concentrations of protozoa were determined at 5 and 20 h postfeeding. Apparent generation rate/h = natural log of ([concentration of protozoa at 20 h divided by concentration at 5 h] divided by the time interval, [T20 to T5]). Alteration of the feed to protozoa ratio by starvation and by changing the level of feed (200 to 900 g/day) showed that as the ratio of feed to protozoa increased, generation rate increased. Measurements of liquid turnover rates in the rumen showed that turnover rate decreased as feed level decreased. Turnover rate was near zero when the sheep were starved. Small quantities of soluble substrates, added directly to the rumen of starved sheep, maintained the protozoal population when rumen turnover was minimal. Furthermore, as rumen turnover rate increased with increased levels of feed, the effect of substrate on maintaining the protozoal population was negated. Thus, at high feed levels, turnover rate may be the dominant factor controlling the establishment and concentration of protozoa in the rumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202706"} {"pmid": "4202707", "title": "Effect of propylene oxide treatment on the microflora of pecans.", "content": "Effect of propylene oxide treatment on the microflora of pecans. Studies were conducted to determine the effectiveness of propylene oxide (PO) treatment in controlling the microflora of pecans. As used commercially, PO has little effect on internal bacteria and fungi in pecan halves. Tests of surface washings of commercially treated pecans showed a reduction of 96% in coliform bacteria following PO treatment. Under controlled laboratory conditions, PO gave 80 to 92% reduction of surface microflora and at least 64% reduction of internal flora, but neither bacteria nor fungi could be eliminated completely, even with high dosages. Current assay methods for determining bacterial content of nutmeats were shown to be inadequate because they utilize only surface washings and thus do not give an accurate picture of the total bacterial population of the nutmeat. Consequently, such assays do not permit an accurate assessment of any potential health hazard related to these organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202707"} {"pmid": "4202708", "title": "New toxin from Aspergillus flavus.", "content": "New toxin from Aspergillus flavus. Two nonaflatoxin-producing isolates of Aspergillus flavus produced a new nonfluorescent nitrogen-containing metabolite that was highly toxic to 1-day-old cockerels. The oral mean lethal dose of toxin was 19 mg/kg. Chemical and physical data obtained on the purified toxin demonstrated that it was not one of the previously reported metabolites of A. flavus. The common name \"flavutoxin\" has been assigned to the toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202708"} {"pmid": "4202709", "title": "Distribution of pyrimidine oligonucleotides in complementary strand fractions of Escherichia coli deoxyribonucleic acid.", "content": "Distribution of pyrimidine oligonucleotides in complementary strand fractions of Escherichia coli deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202709"} {"pmid": "4202710", "title": "Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma.", "content": "Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202710"} {"pmid": "4202711", "title": "Carbonic anhydrase catalyzed hydrolysis and decarboxylation. Kinetic studies of enzyme-catalyzed decomposition of mono- and disubstituted derivatives of carbonic acid.", "content": "Carbonic anhydrase catalyzed hydrolysis and decarboxylation. Kinetic studies of enzyme-catalyzed decomposition of mono- and disubstituted derivatives of carbonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202711"} {"pmid": "4202712", "title": "Multiple forms of galactosyltransferase from bovine milk.", "content": "Multiple forms of galactosyltransferase from bovine milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202712"} {"pmid": "4202713", "title": "Human erythrocyte phosphoglycerate kinase: purification, properties, and interaction with its antibody.", "content": "Human erythrocyte phosphoglycerate kinase: purification, properties, and interaction with its antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202713"} {"pmid": "4202714", "title": "Purification and some properties of rat spleen phospholipase A.", "content": "Purification and some properties of rat spleen phospholipase A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202714"} {"pmid": "4202715", "title": "The effects of Ca2+ on procine enteropeptidase activity.", "content": "The effects of Ca2+ on procine enteropeptidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202715"} {"pmid": "4202716", "title": "Inactivation of infectious deoxyribonucleic acid of bacteriophage phi chi X 174 by colicin E2.", "content": "Inactivation of infectious deoxyribonucleic acid of bacteriophage phi chi X 174 by colicin E2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202716"} {"pmid": "4202717", "title": "Gel electrophoresis of RNA under denaturing conditions.", "content": "Gel electrophoresis of RNA under denaturing conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202717"} {"pmid": "4202718", "title": "Further studies of the fluorescent treponemal antibody-cerebrospinal fluid (FTA-CSF) test with a monospecific anti-IgM conjugate.", "content": "Further studies of the fluorescent treponemal antibody-cerebrospinal fluid (FTA-CSF) test with a monospecific anti-IgM conjugate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202718"} {"pmid": "4202719", "title": "Gonococcal pharyngeal infections. Report of 110 cases.", "content": "Gonococcal pharyngeal infections. Report of 110 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202719"} {"pmid": "4202720", "title": "Neisseria gonorrhoeae identified by the direct fluorescent antibody technique in male contacts.", "content": "Neisseria gonorrhoeae identified by the direct fluorescent antibody technique in male contacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202720"} {"pmid": "4202721", "title": "Studies in venereal disease. II. Improved diagnosis of gonorrhoea by the parallel use of conventional and L-phase media for culture.", "content": "Studies in venereal disease. II. Improved diagnosis of gonorrhoea by the parallel use of conventional and L-phase media for culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202721"} {"pmid": "4202722", "title": "Asymptomatic meningococcal urethritis. Possible protective value against gonococcal infection by bacteriocin production.", "content": "Asymptomatic meningococcal urethritis. Possible protective value against gonococcal infection by bacteriocin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202722"} {"pmid": "4202724", "title": "Long-term triple tetracycline (\"Deteclo\") treatment of non-specific urethritis.", "content": "Long-term triple tetracycline (\"Deteclo\") treatment of non-specific urethritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202724"} {"pmid": "4202723", "title": "Comparison of trimethoprim-sulphamethoxazole and penicillin in the treatment of gonorrhoea.", "content": "Comparison of trimethoprim-sulphamethoxazole and penicillin in the treatment of gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202723"} {"pmid": "4202725", "title": "Sialic acid content of red blood cells from protein-calorie malnourished children and during recovery, and from normal children and adults.", "content": "Sialic acid content of red blood cells from protein-calorie malnourished children and during recovery, and from normal children and adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202725"} {"pmid": "4202727", "title": "Editorial: Carbon monoxide, smoking and cardiovascular disease.", "content": "Editorial: Carbon monoxide, smoking and cardiovascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202727"} {"pmid": "4202729", "title": "Fab-related fragments of human IgG produced by partial tryptic proteolysis.", "content": "Fab-related fragments of human IgG produced by partial tryptic proteolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202729"} {"pmid": "4202728", "title": "Salicylamide glucuronide formation in newborns with severe jaundice of unknown etiology and due to glucose-6-phosphate dehydrogenase deficiency in Greece.", "content": "Salicylamide glucuronide formation in newborns with severe jaundice of unknown etiology and due to glucose-6-phosphate dehydrogenase deficiency in Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202728"} {"pmid": "4202730", "title": "Isolation of immunochemically pure IgE from serum of E-myeloma patient Yu.", "content": "Isolation of immunochemically pure IgE from serum of E-myeloma patient Yu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202730"} {"pmid": "4202731", "title": "Formation of a hemolytically active cellular intermediate by the interaction between properdin factors B and D and the activated third component of complement.", "content": "Formation of a hemolytically active cellular intermediate by the interaction between properdin factors B and D and the activated third component of complement. The present studies demonstrate that the factor B-dependent C3 convertase can be affixed to an erythrocyte by use of an intermediate bearing C3b and that this convertase brings the hemolytic reaction to completion with an efficiency comparable to that of classical convertase. The evidence that the EAC43 intermediate was lysed by a new pathway includes requirements for factors B and D and cell-bound C3b for subsequent lysis by the terminal components, C3-C9. The linear stoichiometry of the effective molecule titrations of C3b and factor B, and the first-order kinetics displayed by the generation and decay of the factor B-dependent hemolytic site are characteristics consistent with the one-hit theory as initially developed for the classical complement system. The use of hemolytically active cellular intermediates to examine the reactions occurring with C3b and factors B and D has allowed extension of the one-hit theory to this molecular sequence, development of effective molecule titrations, recognition of the analogies to the functional characteristics of the classical C3 convertase, and discrimination of the probable mechanism of terminal complement activation from reactive lysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202731"} {"pmid": "4202732", "title": "Influence of erythrocyte membrane components on malaria merozoite invasion.", "content": "Influence of erythrocyte membrane components on malaria merozoite invasion. Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus erythrocytes was unaffected by pretreatment with these enzymes. Differences in membrane structure of erythrocytes from various species may explain the absence of an enzyme effect on rhesus erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202732"} {"pmid": "4202733", "title": "The usefulness of thyrotropin-releasing factor (TRF) test in patients with hypothalamic-pituitary disorders.", "content": "The usefulness of thyrotropin-releasing factor (TRF) test in patients with hypothalamic-pituitary disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202733"} {"pmid": "4202734", "title": "New aspects in the biological role of zinc: a stabilizer of macromolecules and biological membranes.", "content": "New aspects in the biological role of zinc: a stabilizer of macromolecules and biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202734"} {"pmid": "4202735", "title": "Methadone inhibition of glycogen synthase and phosphorylase in rat skeletal muscle.", "content": "Methadone inhibition of glycogen synthase and phosphorylase in rat skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202735"} {"pmid": "4202736", "title": "A kinetic study of the participation of zinc in human spermatozoa metabolism.", "content": "A kinetic study of the participation of zinc in human spermatozoa metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202736"} {"pmid": "4202737", "title": "Antigenic independence of the two types of alkaline phosphatases from Serratia marcescens strain 211.", "content": "Antigenic independence of the two types of alkaline phosphatases from Serratia marcescens strain 211.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202737"} {"pmid": "4202740", "title": "HMO performance: the recent evidence.", "content": "HMO performance: the recent evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202740"} {"pmid": "4202739", "title": "Inhibition of insulin release during hypovolemic shock.", "content": "Inhibition of insulin release during hypovolemic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202739"} {"pmid": "4202741", "title": "Willebrand factor: immunological and biological study.", "content": "Willebrand factor: immunological and biological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202741"} {"pmid": "4202742", "title": "Proceedings: Perhexiline versus prenylamine. A controlled clinical trial in coronary insufficiency.", "content": "Proceedings: Perhexiline versus prenylamine. A controlled clinical trial in coronary insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202742"} {"pmid": "4202743", "title": "[Proceedings: Review of the cardiovascular pharmacology of perhexiline].", "content": "[Proceedings: Review of the cardiovascular pharmacology of perhexiline].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202743"} {"pmid": "4202744", "title": "Proceedings: Experience with the use of perhexiline in patients with chronic coronary insufficiency: preliminary report.", "content": "Proceedings: Experience with the use of perhexiline in patients with chronic coronary insufficiency: preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202744"} {"pmid": "4202745", "title": "Effect of ageing on the levels of the main classes of serum immunoglobulins in active chronic hepatitis and in clinically healthy subjects.", "content": "Effect of ageing on the levels of the main classes of serum immunoglobulins in active chronic hepatitis and in clinically healthy subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202745"} {"pmid": "4202750", "title": "Hog cholera (European swine fever).", "content": "Hog cholera (European swine fever).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202750"} {"pmid": "4202752", "title": "Biphenyl-exposed rabbits.", "content": "Biphenyl-exposed rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202752"} {"pmid": "4202751", "title": "Pharmacokinetic evaluation of penicillin and cephalosporin derivatives in serum and milk of lactating cows and ewes.", "content": "Pharmacokinetic evaluation of penicillin and cephalosporin derivatives in serum and milk of lactating cows and ewes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202751"} {"pmid": "4202754", "title": "Control of magnesium-protoporphyrin chelatase activity in Rhodopseudomonas spheroides. Role of light, oxygen, and electron and energy transfer.", "content": "Control of magnesium-protoporphyrin chelatase activity in Rhodopseudomonas spheroides. Role of light, oxygen, and electron and energy transfer. 1. Magnesium-protoporphyrin chelatase activity, previously shown in whole cells of Rhodopseudomonas spheroides, could not be demonstrated in cell-free extracts prepared in different ways, although spheroplasts retained moderate activity. Slight activity was detected also in whole cells of Rhodospirillum rubrum. 2. The effects on the activity of the enzyme of inhibitors of electron and energy transfer were studied in whole cells of Rps. spheroides. Amytal, rotenone, azide and cyanide inhibited at low pO(2) in the dark but not under anaerobic conditions in the light. Antimycin A and 2-heptyl-4-hydroxyquinoline N-oxide, as well as uncouplers and oligomycin, inhibited under all environmental conditions. 3. The effects on magnesium chelatase activity of intermediates of the tricarboxylic acid cycle, of thenoyltrifluoroacetone, of a number of artificial electron donors or acceptors, of various quinones and of the oxidation-reduction indicator dyes Benzyl Viologen and Methyl Viologen are described. 4. It was concluded that electron transport between a b-type and a c-type cytochrome as well as associated energy conservation and transformation reactions were essential for activity. There was also a specific requirement for ATP. 5. Exogenous protoporphyrin and magnesium protoporphyrin monomethyl ester were incorporated into bacteriochlorophyll or late precursors by whole cells. 6. Evidence is presented that the insertion of magnesium was the only step inhibited by oxygen in the biosynthetic pathway between protoporphyrin and bacteriochlorophyll.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202754"} {"pmid": "4202756", "title": "Stimulation of non-conservative DNA synthesis by ultraviolet light in freeze-treated Bacillus subtilis.", "content": "Stimulation of non-conservative DNA synthesis by ultraviolet light in freeze-treated Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202756"} {"pmid": "4202755", "title": "Binding of parathyroid hormone to bovine kidney-cortex plasma membranes.", "content": "Binding of parathyroid hormone to bovine kidney-cortex plasma membranes. 1. Plasma membranes were purified from bovine kidney cortex, with a fourfold increase in specific activity of parathyroid hormone-sensitive adenylate cyclase over that in the crude homogenate. The membranes were characterized by enzyme studies. 2. Parathyroid hormone was labelled with (125)I by an enzymic method and the labelled hormone shown to bind to the plasma membranes and to be specifically displaced by unlabelled hormone. Parathyroid hormone labelled by the chloramine-t procedure showed no specific binding. (75)Se-labelled human parathyroid hormone, prepared in cell culture, also bound to the membranes. 3. Parathyroid hormone was shown to retain biological activity after iodination by the enzymic method, but no detectable activity remained after chloramine-t treatment. 4. High concentration of pig insulin inhibited binding of labelled parathyroid hormone to plasma membranes and partially inhibited the hormone-sensitive adenylate cyclase activity in a crude kidney-cortex preparation. 5. EDTA enhanced and Ca(2+) inhibited binding of labelled parathyroid hormone to plasma membranes. 6. Whereas rat kidney homogenates were capable of degrading labelled parathyroid hormone to trichloroacetic acid-soluble fragments, neither crude homogenates nor purified membranes from bovine kidney showed this property. 7. Binding of parathyroid hormone is discussed in relation to metabolism and initial events in hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202755"} {"pmid": "4202757", "title": "Translational inhibition in extracts from serum-deprived animal cells.", "content": "Translational inhibition in extracts from serum-deprived animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202757"} {"pmid": "4202759", "title": "Maternal age effect associated with yellow pigment in Malpighian tubes of Drosophila melanogaster.", "content": "Maternal age effect associated with yellow pigment in Malpighian tubes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202759"} {"pmid": "4202760", "title": "Growth and enterotoxin B synthesis by Staphylococcus aureus S6 in associative growth with Pseudomonas aeruginosa.", "content": "Growth and enterotoxin B synthesis by Staphylococcus aureus S6 in associative growth with Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202760"} {"pmid": "4202761", "title": "Purification and characterization of Pseudomonas aeruginosa alkaline phosphatase.", "content": "Purification and characterization of Pseudomonas aeruginosa alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202761"} {"pmid": "4202762", "title": "Growth of Streptococcus cremoris and Streptococcus lactis in a chemostat. Production of cells and survival of bacteria during frozen storage.", "content": "Growth of Streptococcus cremoris and Streptococcus lactis in a chemostat. Production of cells and survival of bacteria during frozen storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202762"} {"pmid": "4202765", "title": "Chapter 30. Current status of spinal cord cooling.", "content": "Chapter 30. Current status of spinal cord cooling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202765"} {"pmid": "4202767", "title": "Sedimentation characteristics of thyroglobulin in some amphibians after 131-I iodination in vivo.", "content": "Sedimentation characteristics of thyroglobulin in some amphibians after 131-I iodination in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202767"} {"pmid": "4202768", "title": "Thymidylate synthetase in mutants of Drosophila melanogaster.", "content": "Thymidylate synthetase in mutants of Drosophila melanogaster. Thymidylate synthetase has been examined with respect to the normal pattern of activity throughout the development of the Oregon-R strain of Drosophila melanogaster. Large amounts of the enzyme are present in both the unfertilized and the fertilized eggs. A comparison of the ovarian thymidylate synthetase activity of the Oregon-R strain and the female sterility mutants, fs(2)B, fu, and fs(1)N, indicates variations in the activity of this enzyme in each strain. At four days of age, the ovarian-specific activity of the female sterility mutants is comparable to or less than that of the Oregon-R strain, but it is reduced at fifteen days of age. The enzyme activity per ovary is low in the fs(2)B strain but is similar in the Oregon-R, fu, and fs(1)N strains. When expressed as activity per organism, thymidylate synthetase declines after six to eight hours of development until the minimal level is reached in the late embryonic stage. Enzyme activity rises throughout the larval instars, reaching a maximum immediately after puparium formation. The activity decreases during pupation, but rises again during the first four days of adult life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202768"} {"pmid": "4202769", "title": "Gene conversion and transfer of genetic information within the inverted region of inversion heterozygotes.", "content": "Gene conversion and transfer of genetic information within the inverted region of inversion heterozygotes. Prior studies of recombination which monitor exchange events in exceedingly short intervals (i.e., separable sites within a cistron) reveal that the basic event in recombination involves a non-reciprocal transfer of information, termed conversion. As a logical consequence of the model suggested by the work in Drosophila, the present investigation examined recombination between rosy mutant alleles (ry:3-52.0) in Drosophila melanogaster in a paracentric inversion (In(3R)P(18)) heterozygote, which placed the rosy region approximately at the center of the inverted region. Comparison of the results of this study with experiments carried out in standard chromosome homozygotes reveals a dramatic suppression of classical crossovers between the rosy mutant alleles in the inversion heterozygote. However, conversions continue to occur for all rosy mutant alleles in all heterozygous combinations in the inversion heterozygote. Moreover, the order of magnitude of conversion frequencies seen in the inversion heterozygote does not change from that seen in the standard chromosome homozygote study. The significance of these observations with reference to the role of rearrangements as barriers of information transfer is discussed. Particular attention is directed to the elaborate inversion polymorphisms seen in natural populations, and to notions concerning their role in the evolution of adaptive gene complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202769"} {"pmid": "4202770", "title": "A case of high rate of spontaneous mutation affecting viability in Drosophila melanogaster.", "content": "A case of high rate of spontaneous mutation affecting viability in Drosophila melanogaster. A spontaneous lethal mutation rate approximately twenty to thirty times greater than normal has been discovered in second and third chromosomes derived from an irradiated isogenic line and paired with marked inversion chromosomes. Mutations resulting in reductions of viability of varying magnitude short of complete lethality apparently also occur at a very high rate in the third but not in the second chromosome. The pattern of accumulation of lethal mutations over several generations and viability frequency distributions within generations have been studied in a number of independent experiments. High mutation rate occurs in heterozygous isogenic-derived second and third chromosomes, either together or apart, irrespective of the genetic constitution of nonhomologous chromosomes. High mutation rates were not observed using the same methods with chromosomes of an inbred line from a different source. The possible mechanisms responsible for these results are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202770"} {"pmid": "4202771", "title": "Segmental aneuploidy as a probe for structural genes in Drosophila: mitochondrial membrane enzymes.", "content": "Segmental aneuploidy as a probe for structural genes in Drosophila: mitochondrial membrane enzymes. A method for detecting possible structural genes in D. melanogaster based on gene dosage dependency is presented. By making thirty crosses between Y-autosome translocations, and an attached-4 cross, it is possible to produce large duplications (approximately 150 salivary gland chromosome bands in length) for every autosomal region with the exception of 83DE. The usefulness of the technique was demonstrated by dosage dependency of three known gene-enzyme systems: alpha-glycerophosphate dehydrogenase-1, alcohol dehydrogenase and malate dehydrogenase. A screen for genes affecting two enzymes localized on the inner membrane of the mitochondrion, alpha-glycerophosphate oxidase (alphaGPO) and succinic dehydrogenase (SHD), produced a dosage-sensitive region in each case. Region 50C-52E affected alphaGPO activity and region 28D-29F affected SDH activity. The latter region apparently includes the malic dehydrogenase-1 gene. The methodology and limitations of the technique are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202771"} {"pmid": "4202772", "title": "The crossveinless polygenes in an Iowa population.", "content": "The crossveinless polygenes in an Iowa population. A natural population of Drosophila melanogaster was tested for the presence of crossveinless (cve) alleles over the course of a summer. Approximately 8% of the wild-caught females tested carried enough cve alleles to produce true-breeding crossveinless lines. In some cases, different isofemale lines produced identical cve strains. Also, differences were sometimes observed among independently selected cve sublines of a given isofemale line.-The cv-2 allele was found to occur with a frequency of about 1% to 2%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202772"} {"pmid": "4202773", "title": "The genetic control and biochemical modification of catechol oxidase in maize.", "content": "The genetic control and biochemical modification of catechol oxidase in maize. Three isozyme variants of catechol oxidase have been shown to be determined by alleles of a gene, Cx, which has been located on chromosome 10 less than 0.1 recombination units from the endosperm marker du(1).-The extractable form of the enzyme is modified by an endogeneous \"modifier\" which appears to function as an enzyme substrate. Enzyme and modifier are functionally isolated in intact cells. Modified enzyme has altered kinetics, does not migrate in electrophoresis and most probably results from a \"tanning\" of the enzyme by reaction products. The content of modifier varies in different lines and is genetically determined by gene(s) independent of Cx. Treatment with maleic hydrazide causes a ten-fold reduction in the modifier content of seedlings, allowing the enzyme to be extracted in an unmodified form which will migrate in electrophoresis.-This system of enzyme and modifier fits the requirements of hypersensitive disease resistance in plants and may provide a test system to investigate the biochemical basis of disease resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202773"} {"pmid": "4202774", "title": "Carbonic anhydrase activity in amphibian and reptilian lung: a histochemical and biochemical analysis.", "content": "Carbonic anhydrase activity in amphibian and reptilian lung: a histochemical and biochemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202774"} {"pmid": "4202777", "title": "Energy-dependent release of magnesium from beef heart submitochondrial particles.", "content": "Energy-dependent release of magnesium from beef heart submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202777"} {"pmid": "4202778", "title": "Denaturation of bovine carbonic anhydrase B by guanidine hydrochloride. A process involving separable sequential conformational transitions.", "content": "Denaturation of bovine carbonic anhydrase B by guanidine hydrochloride. A process involving separable sequential conformational transitions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202778"} {"pmid": "4202779", "title": "Purification and properties of a progesterone-induced basic glycoprotein from the uterine fluids of pigs.", "content": "Purification and properties of a progesterone-induced basic glycoprotein from the uterine fluids of pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202779"} {"pmid": "4202780", "title": "Noninvolvement of copper in the L-tryptophan 2,3-digoxygenase reaction.", "content": "Noninvolvement of copper in the L-tryptophan 2,3-digoxygenase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202780"} {"pmid": "4202781", "title": "Control of metabolite secretion in Bacillus subtilis.", "content": "Control of metabolite secretion in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202781"} {"pmid": "4202782", "title": "Chemotactic responses by motile bacteria.", "content": "Chemotactic responses by motile bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202782"} {"pmid": "4202783", "title": "The relationship between the O-antigenic lipopolysaccharides and serological specificity in strains of Pseudomonas aeruginosa of different O-serotypes.", "content": "The relationship between the O-antigenic lipopolysaccharides and serological specificity in strains of Pseudomonas aeruginosa of different O-serotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202783"} {"pmid": "4202784", "title": "The metabolism of 2-oxogluconate by Pseudomonas aeruginosa.", "content": "The metabolism of 2-oxogluconate by Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202784"} {"pmid": "4202786", "title": "The effect of trypsin on the formation of virus-specific surface antigen in cowpox virus-infected cells.", "content": "The effect of trypsin on the formation of virus-specific surface antigen in cowpox virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202786"} {"pmid": "4202785", "title": "Temperature-sensitive events in the growth of alastrim virus in chick embryo cells.", "content": "Temperature-sensitive events in the growth of alastrim virus in chick embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202785"} {"pmid": "4202776", "title": "Dermatological aspects of pseudo-Hurler polydystrophy (mucolipidosis 3).", "content": "Dermatological aspects of pseudo-Hurler polydystrophy (mucolipidosis 3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202776"} {"pmid": "4202787", "title": "Spread of bovine syncytial virus in cell culture.", "content": "Spread of bovine syncytial virus in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202787"} {"pmid": "4202788", "title": "A population model for limited food competition.", "content": "A population model for limited food competition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202788"} {"pmid": "4202789", "title": "Tonic communication: continual effects of discrete signs in animal communication systems.", "content": "Tonic communication: continual effects of discrete signs in animal communication systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202789"} {"pmid": "4202790", "title": "Molecular evolution of myoglobin and the fossil record: a phylogenetic synthesis.", "content": "Molecular evolution of myoglobin and the fossil record: a phylogenetic synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202790"} {"pmid": "4202793", "title": "Immune response to C. albicans in monkeys with experimental candidiasis in the palate.", "content": "Immune response to C. albicans in monkeys with experimental candidiasis in the palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202793"} {"pmid": "4202794", "title": "Histologic variations in the pulp of intact premolars from young individuals.", "content": "Histologic variations in the pulp of intact premolars from young individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202794"} {"pmid": "4202795", "title": "Alkaline phosphatase in the enamel organ of the rat incisor.", "content": "Alkaline phosphatase in the enamel organ of the rat incisor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202795"} {"pmid": "4202799", "title": "The metabolism of ibuprofen.", "content": "The metabolism of ibuprofen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202799"} {"pmid": "4202800", "title": "Demonstration of thyroglobulin in lymph vessels of TSH stimulated guinea pigs by the indirect immunofluorescence technique.", "content": "Demonstration of thyroglobulin in lymph vessels of TSH stimulated guinea pigs by the indirect immunofluorescence technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202800"} {"pmid": "4202801", "title": "Endocrine changes before and after the menarche. 3. Total thyroxine and \"free thyroxine index\", and the binding capacity of thyroxine binding proteins in female adolescents.", "content": "Endocrine changes before and after the menarche. 3. Total thyroxine and \"free thyroxine index\", and the binding capacity of thyroxine binding proteins in female adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202801"} {"pmid": "4202802", "title": "Peripheral plasma levels of oestrone, oestradiol-17beta and progesterone during ovulatory menstrual cycles in the rhesus monkey with special reference to the onset of menstruation.", "content": "Peripheral plasma levels of oestrone, oestradiol-17beta and progesterone during ovulatory menstrual cycles in the rhesus monkey with special reference to the onset of menstruation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202802"} {"pmid": "4202803", "title": "Patterns of circulating oestrone, oestradiol-17beta and progesterone during pregnancy in the rhesus monkey.", "content": "Patterns of circulating oestrone, oestradiol-17beta and progesterone during pregnancy in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202803"} {"pmid": "4202805", "title": "The arterial supply to the lumbo-sacral spinal cord in the monkey: a comparison with man.", "content": "The arterial supply to the lumbo-sacral spinal cord in the monkey: a comparison with man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202805"} {"pmid": "4202804", "title": "Congenital diverticulum of the left ventricle.", "content": "Congenital diverticulum of the left ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202804"} {"pmid": "4202806", "title": "I segment lengths and thin filament periods in skeletal muscle fibers of the Rhesus monkey and the human.", "content": "I segment lengths and thin filament periods in skeletal muscle fibers of the Rhesus monkey and the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202806"} {"pmid": "4202807", "title": "Primary intraorbital meningiomas.", "content": "Primary intraorbital meningiomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202807"} {"pmid": "4202808", "title": "Changes in blood methanol concentrations in chimpanzees during periods of chronic ethanol ingestion.", "content": "Changes in blood methanol concentrations in chimpanzees during periods of chronic ethanol ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202808"} {"pmid": "4202809", "title": "Barbiturate inhibition of growth and of synthesis of deoxyribonucleic acid, ribonucleic acid and protein in cultured mammalian cells.", "content": "Barbiturate inhibition of growth and of synthesis of deoxyribonucleic acid, ribonucleic acid and protein in cultured mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202809"} {"pmid": "4202810", "title": "Presence of histaminase and ornithine decarboxylase activities in rat thymus.", "content": "Presence of histaminase and ornithine decarboxylase activities in rat thymus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202810"} {"pmid": "4202811", "title": "Effect of cholinesterase inhibitors on active potassium influx in monkey erythrocytes.", "content": "Effect of cholinesterase inhibitors on active potassium influx in monkey erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202811"} {"pmid": "4202815", "title": "Malignant lymphoma with a monoclonal F(ab)mu fragment.", "content": "Malignant lymphoma with a monoclonal F(ab)mu fragment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202815"} {"pmid": "4202817", "title": "An alpha heavy chain abnormality in a child with hypogammaglobulinemia.", "content": "An alpha heavy chain abnormality in a child with hypogammaglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202817"} {"pmid": "4202816", "title": "Immunobiology of human anti-IgM iso-antibodies. I. Clinical and serological studies.", "content": "Immunobiology of human anti-IgM iso-antibodies. I. Clinical and serological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202816"} {"pmid": "4202818", "title": "Isolation and characterization of a non-specific esterase enzyme of Ascaris suum perienteric fluid.", "content": "Isolation and characterization of a non-specific esterase enzyme of Ascaris suum perienteric fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202818"} {"pmid": "4202819", "title": "Disc electrophoresis of Ascaris suum female reproductive system esterase enzymes.", "content": "Disc electrophoresis of Ascaris suum female reproductive system esterase enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202819"} {"pmid": "4202820", "title": "1 Anilino-8-naphthalene sulfonate and n-phenyl-1-naphthylamine as the indicators of bacterial thermosensitivity.", "content": "1 Anilino-8-naphthalene sulfonate and n-phenyl-1-naphthylamine as the indicators of bacterial thermosensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202820"} {"pmid": "4202821", "title": "Identification of a large fragment after limited cyanogen bromide cleavage of fibrinogen.", "content": "Identification of a large fragment after limited cyanogen bromide cleavage of fibrinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202821"} {"pmid": "4202822", "title": "Evidence for a novel DNA component in chloroplasts of Euglena gracilis.", "content": "Evidence for a novel DNA component in chloroplasts of Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202822"} {"pmid": "4202823", "title": "On the specificity of antisera against prostaglandins A2 and E2.", "content": "On the specificity of antisera against prostaglandins A2 and E2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202823"} {"pmid": "4202824", "title": "Variable J-chain content in human IgM.", "content": "Variable J-chain content in human IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202824"} {"pmid": "4202825", "title": "A glycosphingolipid sharing reactivity with both wheat germ lectin and \"carcinoembryonic antisera (Gold)\": partial identity of these reactive sites.", "content": "A glycosphingolipid sharing reactivity with both wheat germ lectin and \"carcinoembryonic antisera (Gold)\": partial identity of these reactive sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202825"} {"pmid": "4202826", "title": "Analytical determination of the buoyant density of DNA in acrylamide gels after preparative CsCl gradient centrifugation.", "content": "Analytical determination of the buoyant density of DNA in acrylamide gels after preparative CsCl gradient centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202826"} {"pmid": "4202827", "title": "Urinary proteins of the normal rat.", "content": "Urinary proteins of the normal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202827"} {"pmid": "4202828", "title": "Humoral and cellular immunity in the anergic tuberculosis patient. A prospective study.", "content": "Humoral and cellular immunity in the anergic tuberculosis patient. A prospective study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202828"} {"pmid": "4202829", "title": "Role of adipose tissue lipolysis in postnatal amelioration of thermogenesis in domestic and wild piglets.", "content": "Role of adipose tissue lipolysis in postnatal amelioration of thermogenesis in domestic and wild piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202829"} {"pmid": "4202830", "title": "The structural gene for the ribosomal protein S18 in Escherichia coli. II. Chemical studies on the protein S18 having an altered electrophoretic mobility.", "content": "The structural gene for the ribosomal protein S18 in Escherichia coli. II. Chemical studies on the protein S18 having an altered electrophoretic mobility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202830"} {"pmid": "4202831", "title": "Fine structure and life cycle of Lankesteria clarki sp. n. (Sporozoa: Eugregarinida) parasitic in the mosquito Aedes sierrensis (Ludlow).", "content": "Fine structure and life cycle of Lankesteria clarki sp. n. (Sporozoa: Eugregarinida) parasitic in the mosquito Aedes sierrensis (Ludlow).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202831"} {"pmid": "4202832", "title": "Immunogenicity and infectivity of sporozoites of mammalian malaria isolated by density-gradient centrifugation.", "content": "Immunogenicity and infectivity of sporozoites of mammalian malaria isolated by density-gradient centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202832"} {"pmid": "4202833", "title": "DNA and RNA syntheses by intraerythrocytic stages of Plasmodium knowlesi.", "content": "DNA and RNA syntheses by intraerythrocytic stages of Plasmodium knowlesi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202833"} {"pmid": "4202834", "title": "Localization of some enzymes of beta-oxidation of fatty acids in the peroxisomes of Tetrahymena.", "content": "Localization of some enzymes of beta-oxidation of fatty acids in the peroxisomes of Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202834"} {"pmid": "4202837", "title": "Hormonal responses to intravenous alimentation.", "content": "Hormonal responses to intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202837"} {"pmid": "4202838", "title": "Filter system for intravenous alimentation.", "content": "Filter system for intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202838"} {"pmid": "4202839", "title": "Alteration in heterocyst pattern of Anabaena produced by 7-azatryptophan.", "content": "Alteration in heterocyst pattern of Anabaena produced by 7-azatryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202839"} {"pmid": "4202840", "title": "Slow rate of evolution of alpha A chain of alpha-crystallin.", "content": "Slow rate of evolution of alpha A chain of alpha-crystallin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202840"} {"pmid": "4202842", "title": "Memory establishment via the anterior commissure of monkeys.", "content": "Memory establishment via the anterior commissure of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202842"} {"pmid": "4202844", "title": "The presence of ribonucleotides in mature closed-circular mitochondrial DNA.", "content": "The presence of ribonucleotides in mature closed-circular mitochondrial DNA. Mitochondrial DNA from mouse and HeLa cells is nicked by alkali and chick-embryo ribonuclease H. It has been concluded that ribonucleotides are present in the closed-circular duplex. A comparative study of the scission rates at pH 13.0 of RNA and of mitochondrial DNAs indicates that there are no more than 10 ribonucleotides in the major fraction of the mitochondrial DNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202844"} {"pmid": "4202843", "title": "A general theory of carcinogenesis.", "content": "A general theory of carcinogenesis. A GENERAL HYPOTHESIS OF CARCINOGENESIS IS PROPOSED CONSISTING OF THE FOLLOWING FEATURES: (1) It is suggested that all cells possess multiple structural genes (Tr) capable of coding for transforming factors which can release the cell from its normal constraints on growth. (2) In adult cells they are suppressed by diploid pairs of regulatory genes and some of the transforming genes are tissue specific. (3) The Tr loci are temporarily activated at some stage of embryogenesis and possibly during some stage of the cell cycle in adult cells. (4) Spontaneous tumors, or tumors induced by chemicals or radiation, arise as the result of a double mutation of any set of regulatory genes releasing the suppression of the corresponding Tr genes and leading to transformation of the cell. (5) Autosomal dominant hereditary tumors, such as retinoblastoma, are the result of germ-line inheritance of one inactive regulatory gene. Subsequent somatic mutation of the other regulatory gene leads to tumor formation. (6) The Philadelphia chromosome produces inactivation of one regulatory gene by position effect. A somatic mutation of the other leads to chronic myelogenous leukemia. (7) Oncogenic viruses evolved by the extraction of host Tr genes with their conversion to viral transforming genes. As a result, in addition to the above mechanisms, tumors may also be produced by the reintroduction of these genes into susceptible host cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202843"} {"pmid": "4202845", "title": "Production of a noncovalently bonded pentamer of immunoglobulin M: relationship of J chain.", "content": "Production of a noncovalently bonded pentamer of immunoglobulin M: relationship of J chain. Human immunoglobulin M was reduced with concentrations of 2-mercaptoethylamine chosen so that approximately 40% of the immunoglobulin M was reduced to 7S subunits. Under these conditions, which selectively cleave intersubunit disulfides, J chain was released. The 7S subunits of immunoglobulin M so produced did not contain J chain. The high-molecular-weight immunoglobulin M remaining after treatment with 2-mercaptoethylamine had a sedimentation coefficient of 18.0 S and molecular weight of 1 million, and dissociated in 4 M guanidine into subunits similar in size to the 7S subunits. J chain was found in the 18.0S, noncovalently linked immunoglobulin M from which it was released only after more complete reduction with 10 mM dithiothreitol. The results are consistent with the hypothesis that J chain participates in the formation of the intersubunit linkages. However, it need not necessarily be directly involved in all of the intersubunit disulfides. It may play an important role in modulating the assembly of immunoglobulin M subunits, perhaps by inducing conformational changes that lead to noncovalent interactions between the subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202845"} {"pmid": "4202846", "title": "On the amino-acid sequence of flagellin from Bacillus subtilis 168: comparison with other bacterial flagellins.", "content": "On the amino-acid sequence of flagellin from Bacillus subtilis 168: comparison with other bacterial flagellins. A partial amino-acid sequence of Bacillus subtilis 168 flagellin is presented. The region of unassigned sequence in this 304-residue polypeptide chain spans residues 158-173. Comparison of the 27-residue aminoterminal CNBr peptide of B. subtilis 168 flagellin with that derived from the flagellin of the serologically unrelated strain of B. subtilis, W23, shows only three conservative substitutions, whereas the 16-residue carboxyl-terminal peptides derived from these flagellins were identical. The comparison of the very limited sequence information available on the flagellins of Salmonella and Proteus with that on B. subtilis indicates homology between these proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202846"} {"pmid": "4202847", "title": "A wet chemical method for rendering scanning electron microscopy samples conductive and observations on the surface morphology of human erythrocytes and Ehrlich ascites cells.", "content": "A wet chemical method for rendering scanning electron microscopy samples conductive and observations on the surface morphology of human erythrocytes and Ehrlich ascites cells. An alternate method to the common technique of evaporating a metallic coating on cells to render them conductive for scanning electron microscopy is described. This wet chemical technique is less expensive and easier to use, but is not as widely applicable as the evaporative technique. It should prove invaluable in the identification of artifacts by comparison of micrographs of material prepared in both manners. The first step in our application of this wet chemical method is to use the Centrifugal Cytology bucket to deposit the cells onto conductive polyethylene. After centrifugation and fixation with 4% glutaraldehyde, the sample is placed in a 50% glutaraldehyde solution. After a rinse in distilled water it is treated with ammoniacal silver nitrate. The reduced silver renders the sample conductive and, thus, for erythrocytes, eliminates artifacts due to charging and reduces these artifacts to virtually acceptable levels for larger cells. The surfaces of erythrocytes appear smooth with this technique while those coated by conventional vapor deposition of Au-Pd alloys often appear slightly wrinkled. Ehrlich ascites cells apparently can be divided into two classes by surface morphology. The surface structure of Ehrlich ascites cells rendered conductive by the wet method appears to be finer than conventionally prepared ones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202847"} {"pmid": "4202852", "title": "The projections of the medial geniculate complex within the sylvian fissure of the rhesus monkey.", "content": "The projections of the medial geniculate complex within the sylvian fissure of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202852"} {"pmid": "4202851", "title": "Thrombogenic properties of heparinised vascular catheters.", "content": "Thrombogenic properties of heparinised vascular catheters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202851"} {"pmid": "4202853", "title": "The visuotopic organization of the superior colliculus of the owl monkey (Aotus trivirgatus) and the bush baby (Galago senegalensis).", "content": "The visuotopic organization of the superior colliculus of the owl monkey (Aotus trivirgatus) and the bush baby (Galago senegalensis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202853"} {"pmid": "4202841", "title": "Supraspinal control over segmental centers of antagonist muscles in man. 3. Tuning of spinal reciprocal inhibition system during organization preceding voluntary movement.", "content": "Supraspinal control over segmental centers of antagonist muscles in man. 3. Tuning of spinal reciprocal inhibition system during organization preceding voluntary movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202841"} {"pmid": "4202854", "title": "Changes in cerebroside synthetic activities of the brain with development of the rhesus monkey (Macaca mulatta).", "content": "Changes in cerebroside synthetic activities of the brain with development of the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202854"} {"pmid": "4202855", "title": "Two cases of apparent exclusion of maternity caused by Rh chromosome deletion.", "content": "Two cases of apparent exclusion of maternity caused by Rh chromosome deletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202855"} {"pmid": "4202856", "title": "Planning the nutrition component of long-term care.", "content": "Planning the nutrition component of long-term care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202856"} {"pmid": "4202857", "title": "Effects of protein deficiency on serum albumin-synthesizing activity of rat liver--with special reference to the presence of transcriptional controls.", "content": "Effects of protein deficiency on serum albumin-synthesizing activity of rat liver--with special reference to the presence of transcriptional controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202857"} {"pmid": "4202858", "title": "Immunological studies on the light chains of myosin with special reference to the relationship between light chain components.", "content": "Immunological studies on the light chains of myosin with special reference to the relationship between light chain components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202858"} {"pmid": "4202859", "title": "The purification and properties of cytidine deaminase from Escherichia coli.", "content": "The purification and properties of cytidine deaminase from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202859"} {"pmid": "4202861", "title": "Further studies on a specific basic protein from bread wheat.", "content": "Further studies on a specific basic protein from bread wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202861"} {"pmid": "4202862", "title": "A study on antibodies produced with liver tissue containing Australia antigen and virus-like particles.", "content": "A study on antibodies produced with liver tissue containing Australia antigen and virus-like particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202862"} {"pmid": "4202863", "title": "Experimental avian aspergillosis.", "content": "Experimental avian aspergillosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202863"} {"pmid": "4202864", "title": "Rapid diagnosis of pulmonary mycosis by counterelectrophoresis.", "content": "Rapid diagnosis of pulmonary mycosis by counterelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202864"} {"pmid": "4202874", "title": "The effect of plasma and plasma derivative infusion in the mucopolysaccharidoses.", "content": "The effect of plasma and plasma derivative infusion in the mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202874"} {"pmid": "4202875", "title": "Left ventricular volume changes after amyl nitrite and nitroglycerin in man as measured by ultrasound.", "content": "Left ventricular volume changes after amyl nitrite and nitroglycerin in man as measured by ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202875"} {"pmid": "4202877", "title": "Genetic polymorphism of mannosephosphate isomerase in Primates.", "content": "Genetic polymorphism of mannosephosphate isomerase in Primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202877"} {"pmid": "4202878", "title": "Genetic polymorphism of isocitrate dehydrogenase in Primates.", "content": "Genetic polymorphism of isocitrate dehydrogenase in Primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202878"} {"pmid": "4202879", "title": "Transspecific variability of carbonic anhydrase I in Primates.", "content": "Transspecific variability of carbonic anhydrase I in Primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202879"} {"pmid": "4202880", "title": "Genetic polymorphism of liver esterases in Primates. I. Papio cynocephalus (Linnaeus, 1766).", "content": "Genetic polymorphism of liver esterases in Primates. I. Papio cynocephalus (Linnaeus, 1766).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202880"} {"pmid": "4202881", "title": "Titres of Australia (hepatitis-associated) antigen in healthy carriers, leprosy, cirrhosis of the liver and acute hepatitis.", "content": "Titres of Australia (hepatitis-associated) antigen in healthy carriers, leprosy, cirrhosis of the liver and acute hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202881"} {"pmid": "4202882", "title": "Simian model for the evaluation of immunity to influenza.", "content": "Simian model for the evaluation of immunity to influenza. Rhesus monkeys (Macaca mulatta) exposed to small-particle aerosols of the Aichi strain of type A2 influenza virus responded by shedding virus from the nasopharynx for 7 to 9 days and by seroconversion (hemagglutination inhibition) 8 or 9 days after exposure. After rechallenge with the homologous virus, no replication of the organism was observed, and a serological anamnestic reaction occurred. The data indicate that the rhesus monkey is a useful primate model for evaluating induced immunity to influenza virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202882"} {"pmid": "4202883", "title": "Purification and characterization of Pseudomonas aeruginosa exotoxin.", "content": "Purification and characterization of Pseudomonas aeruginosa exotoxin. A trypsin-sensitive, heat-labile exotoxin of Pseudomonas aeruginosa strain P-A-103 has been purified by a procedure that includes membrane ultrafiltration, hydroxylapatite chromatography, ion-exchange cellulose chromatography, and gel filtration chromatography. The procedure resulted in the recovery of 48% of the exotoxin with a 40-fold increase in specific activity (micrograms of protein per median lethal dose [LD(50)]). The mean lethal dose of the purified toxin administered intravenously into mice weighing 20 g was approximately 6 mug of protein. The toxin contained virtually no nucleic acid, detectable pigment, or lipopolysaccharide. When subjected to sodium dodecyl sulfate polyacrylamide gel electrophoresis, the toxin separated into at least six protein components which appeared to have similar molecular weights. The estimated molecular weight of the toxin is 54,000, and its isoelectric point is 5.0", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202883"} {"pmid": "4202885", "title": "Isolation of a specific enhancer for echovirus 6 from uninfected permissive host cells.", "content": "Isolation of a specific enhancer for echovirus 6 from uninfected permissive host cells. A specific enhancer for the m+ variant of echovirus 6 was isolated from uninfected, permissive host cells. The enhancer transferred the susceptibility to virus infection from permissive cells to less susceptible cells. Enhancer activity in cultured, human cells (WISH) was released by these cells into extracellular fluids at a linear rate. Maximal enhancer activity was recovered from cell monolayers that were extracted with buffered salt solutions (pH 6.6) for 5 h at 37 C. Crude enhancer preparations contained substances that reduced virus titers in permissive host cells and suppressed some of the enhancer activity. Viral inhibitory activity was removed from cellular extracts by either differential centrifugation or ion exchange chromatography. The enhancer, in contrast to inhibitory substances, remained in supernatant fractions after centrifugation at 110,000 x g for 4 h and adsorbed to diethylaminoethyl-Sephadex columns. Enhancer preparations that were devoid of inhibitory activity increased the virus titers in less susceptible simian cell cultures (approximately 100-fold) to the titers attained by fully permissive human cell cultures. A direct relationship between protein concentration and enhancer activity in cellular extracts was demonstrated. Partial purification of the enhancer by differential centrifugation and ammonium sulfate precipitation increased the specific activity of enhancer (units/mg of protein) by 13-fold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202885"} {"pmid": "4202884", "title": "Effects of antithymocyte sera and antimacrophage sera on cell-mediated immune reactions in Listeria-infected mice.", "content": "Effects of antithymocyte sera and antimacrophage sera on cell-mediated immune reactions in Listeria-infected mice. The cell-mediated immune responses of allograft rejection, delayed hypersensitivity, and resistance to Listeria monocytogenes were suppressed by injections of antithymocyte serum (ATS), but the immune responses were not significantly altered by antimacrophage serum (AMS) or normal rabbit serum (NRS). Antisera were prepared in rabbits against purified mouse thymocytes and purified peritoneal macrophages. When mice were injected with ATS near the time of skin grafting, allografts survived significantly longer. Similar administration of AMS or NRS failed to alter the course of graft rejection. Decreased footpad swelling indicated the suppression of delayed hypersensitivity in mice injected with ATS 6 days after a sublethal inoculation of Listeria cells. None of the serum treatments affected the ultimate survival of mice infected with a small number of bacteria. Either ATS or NRS was injected into immunized mice 1 day before and 2 days after a challenge inoculation of Listeria cells. Pronounced suppression of delayed hypersensitivity was found in the ATS-treated groups, along with extensive mortalities that reached 100% in the group receiving the largest dose of ATS. All control animals survived and demonstrated strong delayed hypersensitivity reactions. Antimacrophage serum had no significant effect on the three mechanisms of cell-mediated immunity that were tested. The lymphoid cells which mediate delayed hypersensitivity, antimicrobial cellular immunity, and allograft rejection possess antigenic determinants in common with thymocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202884"} {"pmid": "4202886", "title": "Lipids of putative relevance to virulence in Mycobacterium tuberculosis: correlation of virulence with elaboration of sulfatides and strongly acidic lipids.", "content": "Lipids of putative relevance to virulence in Mycobacterium tuberculosis: correlation of virulence with elaboration of sulfatides and strongly acidic lipids. From examination of some 40 patient strains of Mycobacterium tuberculosis, a statistically very significant correlation (Spearman's rho) can be drawn between the root index of virulence for the guinea pig (D. A. Mitchison) and the ability of the individual strains to elaborate strongly acidic lipids (SAL) in culture. These include both sulfatides (SL) and phospholipids (PL). Since essentially all, if indeed not all, of the virulent and only few attenuated strains are prolific in elaborating SAL, this criterion may be a necessary requirement for the expression of virulence in M. tuberculosis. Tested by chi-square, this premise is seen to be statistically and pragmatically highly significant. We speculate that SL may contribute to the pathogenesis of tuberculosis because of a demonstrable activity directed against host liver mitochondrial membranes (manuscript in preparation) and its synergistic potentiation of the specific toxicity of trehalose dimycolate (cord factor). The activity may also be expressed against phagosomal and lysosomal membranes within macrophages. Because of their strongly anionic character, SL and PL may interact with cationic sites on lysosomal hydrolases with resultant immobilization and/or inactivation of the enzymes. By a similar mechanism, these ionic lipids may alter the activity of bactericidal basic proteins, previously recognized in the lysosomal armamentarium. Since a minor but significant fraction of demonstrably attenuated strains is nevertheless prolific in SL or SAL elaboration, this facility alone is evidently not a sufficient criterion for expression of virulence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202886"} {"pmid": "4202887", "title": "Characterization and serotyping of three feline reovirus isolates.", "content": "Characterization and serotyping of three feline reovirus isolates. Three feline virus isolates were shown to be members of the reovirus group by their growth characteristics in cell cultures, physicochemical properties, and appearance under an electron microscope. Their close serological relationship to, or identity with, human reovirus type III was revealed by hemagglutination, hemagglutination inhibition, serum neutralization, and gel diffusion tests. One feline isolate (636) was pathogenic for suckling mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202887"} {"pmid": "4202888", "title": "Release of beta-lysin from platelets by thrombin and by a factor produced in heparinized blood.", "content": "Release of beta-lysin from platelets by thrombin and by a factor produced in heparinized blood. Removal of calcium by either citrate, oxalate, or ethylenediaminetetraacetate inhibited coagulation of blood at an early stage and prevented the release of beta-lysin from platelets. In contrast, heparin caused platelet agglutination and stimulated beta-lysin release in vitro and in vivo. This release was calcium dependent and may have been due to a calcium-dependent reaction in the blood coagulation sequence. Thrombin which by-passed the early calcium-dependent stages of coagulation directly stimulated the release of beta-lysin from platelets. However, thrombin alone or in combination with other plasma factors was not as effective in releasing beta-lysin as the regular coagulation process. Thrombin's platelet degranulating activity correlated with its beta-lysin releasing activity. In contrast to thrombin, staphylococcal coagulase, which also by-passed the calcium-dependent stages of coagulation, coagulated citrated blood without releasing beta-lysin. The release of beta-lysin has been observed previously in the absence of blood coagulation, but this is the first observation of coagulation without beta-lysin release. It is clear that beta-lysin is released from platelets during coagulation by the direct action of thrombin and that it may be released in an earlier calcium-dependent reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202888"} {"pmid": "4202889", "title": "Action of group A streptococcus extracellular product(s) on the connective tissue of the bovine heart valve.", "content": "Action of group A streptococcus extracellular product(s) on the connective tissue of the bovine heart valve. Group A streptococcal strains isolated from rheumatic fever patients were cultivated in the presence of bovine heart valves in a medium devoid of components from animal origin. Other group A streptococci and various bacteria were used as controls. The supernatant of these cultures was extracted and analyzed chemically and immunologically. The extracts prepared from cultures of two \"rheumatogenic\" strains in the presence of bovine heart valves showed fraction(s) containing proteins, oses (neutral and amined), and uronic and sialic acids. This fraction(s) was immunologically active with both anti-group A streptococcus and antisoluble connective glycoprotein antisera, with a partial identity reaction. Experiments with a diffusion chamber and attempts to precipitate a postulated enzyme from the culture of these strains by ammonium sulfate suggest that this action is due to an extracellular product of the bacteria. The meaning of these data in the physiopathology of rheumatic cardiac lesions is briefly discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202889"} {"pmid": "4202890", "title": "Role of mycobactin in the growth and virulence of tubercle bacilli.", "content": "Role of mycobactin in the growth and virulence of tubercle bacilli. Tubercle bacilli failed to grow in iron-void media enriched with solutions of iron-containing transferrin (Tr) or ferritin (F) because these substances do not provide the bacilli with iron, which is essential for their growth. Animal serum and macrophages possessed no iron carrier with an ability to satisfy the need of the bacteria for the metal. Mycobactin (M), the growth-product of tubercle bacilli, removed iron from Tr and F and supplied the metal for bacillary utilization. The role of M in the growth of tubercle bacilli was influenced by nonionic surfactants which inhibited bacillary growth by removing M from the bacillary cells and interfering with the absorption of M-iron complexes. Experiments with Tween 80, Triton WR-1339, and lecithin showed that avirulent bacilli lose M at lower concentrations of the surfactants than virulent bacilli. Since avirulent and virulent bacilli possess the same amount of M, these findings indicate that M is bound more firmly to lipid-rich virulent than lipid-poor avirulent cells. These findings indicate that the resistance of virulent bacilli to the M-removing activity of the surfactants is an indicator of their ability to multiply in the infected host and may be used as a measure of bacillary virulence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202890"} {"pmid": "4202891", "title": "Reactivity of purified proteins and polysaccharides from Mycobacterium tuberculosis in delayed skin test and cultured lymphocyte mitogenesis assays.", "content": "Reactivity of purified proteins and polysaccharides from Mycobacterium tuberculosis in delayed skin test and cultured lymphocyte mitogenesis assays. Hypersensitivity responses to two highly purified and well characterized mycobacterial proteins and a preparation of mycobacterial arabinogalactanarabinomannan were studied by using guinea pig skin tests and in vitro-cultured human lymphocyte mitogenesis stimulation assays. The purified proteins were found to elicit delayed-type hypersensitivity skin test reactions and to stimulate mitogenesis in cultured lymphocytes. The polysaccharide preparation was found to evoke delayed skin tests but not to stimulate cultured lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202891"} {"pmid": "4202893", "title": "Benign intra-osseous cysts of the jaws.", "content": "Benign intra-osseous cysts of the jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202893"} {"pmid": "4202892", "title": "Antigens of Streptococcus mutans. II. Characterization of an antigen resembling a glycerol teichoic acid in walls of strain BHT.", "content": "Antigens of Streptococcus mutans. II. Characterization of an antigen resembling a glycerol teichoic acid in walls of strain BHT. Cold 10% trichloroacetic acid was used to extract antigens from purified cell walls of Streptococcus mutans BHT. Column chromatography on Biogel P-100 resolved two serologically reactive fractions (B and C). These fractions were ascertained to be relatively pure by recycling on Biogel P-100, Ouchterlony double-diffusion analysis, and immunoelectrophoresis. Fractions B and C demonstrated bands of absolute homology by double-diffusion but different mobilities by immunoelectrophoresis. Chemical analysis indicated that fraction B is a polysaccharide composed principally of rhamnose and galactose, with smaller amounts of glucose and glucosamine. Small quantities of glycerol and phosphorus also were found. Fraction C was composed mainly of galactose, glycerol, and phosphorus. Alkaline hydrolysis of this fraction yielded products typically released by the degradation of a glycerol teichoic acid, such as glycerol monophosphate, glycerol diphosphate, inorganic phosphorus, and several glycosyl glycerol phosphates. Diglycerol triphosphate was not detected. Side-group analysis revealed that glycerol was substituted by mono- and trigalactosyl moieties. Fraction C was deduced to contain 25 glycerol phosphate units per polymer length. Hapten inhibition studies revealed a beta-galactoside as the probable hapten on this antigen. The BHT teichoic acid reacted strongly with FA-1 antiserum. It showed bands of homology with both BHT and FA-1 crude acid extracts upon double-diffusion, using antisera to either strain. The BHT teichoic acid also displayed immunoelectrophoretic behavior identical to one of the mobile FA-1 cell wall antigens, again using either serum to develop precipitin bands. It is concluded this antigen may possess a serotype-specific determinant for S. mutans serotype b.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202892"} {"pmid": "4202894", "title": "A survey of school dental health programs in the state of Connecticut.", "content": "A survey of school dental health programs in the state of Connecticut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202894"} {"pmid": "4202895", "title": "A national leader observes and reflects.", "content": "A national leader observes and reflects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202895"} {"pmid": "4202896", "title": "An immunodiffusion analysis of Mycobacterium lepraemurium Marchoux and Sorel.", "content": "An immunodiffusion analysis of Mycobacterium lepraemurium Marchoux and Sorel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202896"} {"pmid": "4202898", "title": "The sensitivity of Brucella abortus to chemotherapeutic agents.", "content": "The sensitivity of Brucella abortus to chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202898"} {"pmid": "4202897", "title": "The serological response to Aspergillus fumigatus in experimental mycotic abortion in sheep.", "content": "The serological response to Aspergillus fumigatus in experimental mycotic abortion in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202897"} {"pmid": "4202899", "title": "Pyocin-sensitivity testing as a means of typing Pseudomonas aeruginosa.", "content": "Pyocin-sensitivity testing as a means of typing Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202899"} {"pmid": "4202900", "title": "Proceedings: The effect of tissue-culture cells in promoting prolonged survival of Neisseria gonorrhoeae in artificial subcutaneous cavities of mice.", "content": "Proceedings: The effect of tissue-culture cells in promoting prolonged survival of Neisseria gonorrhoeae in artificial subcutaneous cavities of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202900"} {"pmid": "4202901", "title": "Proceedings: Corynecine typing of diphtheria bacilli.", "content": "Proceedings: Corynecine typing of diphtheria bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202901"} {"pmid": "4202902", "title": "Letter: Crystallization and preliminary x-ray investigation of bovine erythrocyte carbonic anhydrase.", "content": "Letter: Crystallization and preliminary x-ray investigation of bovine erythrocyte carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202902"} {"pmid": "4202904", "title": "Electrophoretic and immunological studies on the light chains of myosin.", "content": "Electrophoretic and immunological studies on the light chains of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202904"} {"pmid": "4202905", "title": "Relation between seramarcide, an antitussive for dogs and serratigen from Serratia marcescens.", "content": "Relation between seramarcide, an antitussive for dogs and serratigen from Serratia marcescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202905"} {"pmid": "4202906", "title": "Electrophoretic and immunological studies on the light chains of myosin.", "content": "Electrophoretic and immunological studies on the light chains of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202906"} {"pmid": "4202909", "title": "Neuroleptanalgesia in small animals.", "content": "Neuroleptanalgesia in small animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202909"} {"pmid": "4202916", "title": "Circulatory effects of splenectomy in the horse. I. Effect on red-cell distribution and variability of haematocrit in the peripheral blood.", "content": "Circulatory effects of splenectomy in the horse. I. Effect on red-cell distribution and variability of haematocrit in the peripheral blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202916"} {"pmid": "4202917", "title": "Circulatory effects of splenectomy in the horse. II. Effect on plasma volume and total and circulating red-cell volume.", "content": "Circulatory effects of splenectomy in the horse. II. Effect on plasma volume and total and circulating red-cell volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202917"} {"pmid": "4202903", "title": "One course Sue Barton never took: health care economics.", "content": "One course Sue Barton never took: health care economics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202903"} {"pmid": "4202919", "title": "Experiments on the hepato-oesophageal artery of the mouse.", "content": "Experiments on the hepato-oesophageal artery of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202919"} {"pmid": "4202922", "title": "Intra-abdominal pressure in small ruminants.", "content": "Intra-abdominal pressure in small ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202922"} {"pmid": "4202913", "title": "Immunochemical characteristics and differentiation of Nocardiae.", "content": "Immunochemical characteristics and differentiation of Nocardiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202913"} {"pmid": "4202926", "title": "Effect of contractions in vitro on glycogen content and glycogen synthetase activity in muscle.", "content": "Effect of contractions in vitro on glycogen content and glycogen synthetase activity in muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202926"} {"pmid": "4202925", "title": "Differences in the autoradiographic localization of labelled morphine-like analgesics in the mouse.", "content": "Differences in the autoradiographic localization of labelled morphine-like analgesics in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202925"} {"pmid": "4202927", "title": "Effects of insulin and testosterone on glycogen synthesis and glycogen synthetase activity in rat levator ani muscle.", "content": "Effects of insulin and testosterone on glycogen synthesis and glycogen synthetase activity in rat levator ani muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202927"} {"pmid": "4202928", "title": "The effect of insulin on epinephrine and glucagon inactivated glycogen synthetase I in the isolated perfused rat liver.", "content": "The effect of insulin on epinephrine and glucagon inactivated glycogen synthetase I in the isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202928"} {"pmid": "4202934", "title": "Influence of formaldehyde-treated casein supplements on the concentration of epsilon-N-methyllysine in sheep plasma.", "content": "Influence of formaldehyde-treated casein supplements on the concentration of epsilon-N-methyllysine in sheep plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202934"} {"pmid": "4202937", "title": "Air-blast avoidance learning sets in protein-malnourished monkeys.", "content": "Air-blast avoidance learning sets in protein-malnourished monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202937"} {"pmid": "4202935", "title": "The role in chylomicron formation of phospholipase activity of intestinal Golgi membranes.", "content": "The role in chylomicron formation of phospholipase activity of intestinal Golgi membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202935"} {"pmid": "4202938", "title": "The visual fields of the frog and toad: a comparative study.", "content": "The visual fields of the frog and toad: a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202938"} {"pmid": "4202933", "title": "Nitrogen fixation by Anabaena cylindrica. II. Nitrogenase activity during induction and aging of batch cultures.", "content": "Nitrogen fixation by Anabaena cylindrica. II. Nitrogenase activity during induction and aging of batch cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202933"} {"pmid": "4202936", "title": "Studies on goat anti-CBA thymocyte globulin: the large scale preparation, purification and testing of anti-lymphocyte serum and anti-lymphocyte globulin.", "content": "Studies on goat anti-CBA thymocyte globulin: the large scale preparation, purification and testing of anti-lymphocyte serum and anti-lymphocyte globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202936"} {"pmid": "4202939", "title": "The occurrence of two types of synthesis of deoxyribonucleic acid during normal growth in Bacillus subtilis.", "content": "The occurrence of two types of synthesis of deoxyribonucleic acid during normal growth in Bacillus subtilis. A study of the relative utilization of thymine and thymidine as precursors for DNA synthesis during normal growth in Bacillus subtilis showed that thymine serves preferentially as a precursor for ;repair' synthesis, whereas thymidine is used preferentially for ;replicative' synthesis. Further, evidence was obtained which suggests that during normal growth both ;replicative' and ;repair' DNA syntheses occur simultaneously. ;Repair' synthesis is distinguished not only on the basis of its preferential utilization of thymine but also by its selective inhibition by caffeine. ;Replicative' synthesis, however, is selectively inhibited by 6-(p-hydroxyphenylazo)-uracil. ;Repair' synthesis would seem to be a ;pre-fork' phenomenon and its inhibition is highly lethal to the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202939"} {"pmid": "4202941", "title": "A teaching course in general practice.", "content": "A teaching course in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202941"} {"pmid": "4202940", "title": "The structure of a polymer containing galactosamine from walls of Bacillus subtilis 168.", "content": "The structure of a polymer containing galactosamine from walls of Bacillus subtilis 168. Cell walls of Bacillus subtilis 168 contain a phosphorylated polysaccharide composed of N-acetylgalactosamine, glucose and phosphate. Controlled acid hydrolysis gives 3-O-beta-d-glucopyranosyl-N-acetylgalactosamine with a phosphomonoester group at the 6-position of glucose. It is likely that the polysaccharide consists of disaccharide units connected by phosphodiester residues joining the 1-position of N-acetylgalactosamine to the 6-position of glucose in the neighbouring unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202940"} {"pmid": "4202942", "title": "Interocular transfer in split-brain monkeys following serial disconnection.", "content": "Interocular transfer in split-brain monkeys following serial disconnection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202942"} {"pmid": "4202943", "title": "Cold fiber heat sensitivity: dependency of \"paradoxical\" discharge on body temperature.", "content": "Cold fiber heat sensitivity: dependency of \"paradoxical\" discharge on body temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202943"} {"pmid": "4202945", "title": "Selective removal of albumin from plasma by affinity chromatography.", "content": "Selective removal of albumin from plasma by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202945"} {"pmid": "4202947", "title": "Cell-mediated immune response in malnutrition.", "content": "Cell-mediated immune response in malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202947"} {"pmid": "4202946", "title": "Immune responses in congenitally thymus-less mice. II. Quantitative studies of serum immunoglobulins, the antibody response to sheep erythrocytes, and the effect of thymus allografting.", "content": "Immune responses in congenitally thymus-less mice. II. Quantitative studies of serum immunoglobulins, the antibody response to sheep erythrocytes, and the effect of thymus allografting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202946"} {"pmid": "4202948", "title": "Universal occurrence of antibodies to tubercle bacilli in sera from non-tuberculous and tuberculous individuals.", "content": "Universal occurrence of antibodies to tubercle bacilli in sera from non-tuberculous and tuberculous individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202948"} {"pmid": "4202949", "title": "Rosetting of human red blood cells to thymocytes and thymus-derived cells.", "content": "Rosetting of human red blood cells to thymocytes and thymus-derived cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202949"} {"pmid": "4202953", "title": "Drosophila salivary chromosomes as test system for antinuclear antibody assay.", "content": "Drosophila salivary chromosomes as test system for antinuclear antibody assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202953"} {"pmid": "4202951", "title": "Antigenic changes in transformed FL human amnion cells.", "content": "Antigenic changes in transformed FL human amnion cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202951"} {"pmid": "4202952", "title": "Sensitivity of non-human cells to human lymphocyte 'proliferation inhibitory factor' (PIF) in vitro.", "content": "Sensitivity of non-human cells to human lymphocyte 'proliferation inhibitory factor' (PIF) in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202952"} {"pmid": "4202950", "title": "Inhibition of IgG complex-induced platelet aggregation by antiglobulin-active cryoglobulin IgM components.", "content": "Inhibition of IgG complex-induced platelet aggregation by antiglobulin-active cryoglobulin IgM components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202950"} {"pmid": "4202954", "title": "Immunochemical studies of four human IgM pyroglobulins.", "content": "Immunochemical studies of four human IgM pyroglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202954"} {"pmid": "4202955", "title": "Further studies on the C3b inactivator or conglutinogen activating factor (KAF).", "content": "Further studies on the C3b inactivator or conglutinogen activating factor (KAF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202955"} {"pmid": "4202957", "title": "Comparison of the capillary tube and explant methods for the in vitro assay of tuberculin.", "content": "Comparison of the capillary tube and explant methods for the in vitro assay of tuberculin. Purified antigens prepared from mycobacteria were tested for nonspecific toxicity and tuberculin activity by two in vitro methods. One technique utilized measurements of macrophage migration in 4-day-old cultures of spleen from normal and tuberculin-sensitive rabbits. The other method was a modification of the capillary tube technique. To obtain enough peritoneal macrophages for good quantitation, changes were made in the method of harvesting cells, and in some instances exudates from two or more Wright strain no. 13 guinea pigs were combined. The capillary tube method was as sensitive as the explant method for detecting nonspecific toxicity. Each tuberculin assay included a group of control cultures of cells from sensitive animals, test groups containing two widely spaced concentrations of a standard tuberculin, PPD-S, and one or more concentration of the tuberculin to be tested. Macrophages from tuberculin-sensitive animals were regularly inhibited by 0.25 mug of PPD-S per ml with both in vitro methods. The potency of the test tuberculins relative to that of PPD-S was somewhat greater in capillary tube assays than in explant cultures. A purified tuberculopolysaccharide was equally inhibitory for both normal and tuberculin-sensitive cells in both culture systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202957"} {"pmid": "4202960", "title": "Comparison of strains of BCG. I. Antigenic analysis and tuberculin reactivity.", "content": "Comparison of strains of BCG. I. Antigenic analysis and tuberculin reactivity. At least 10 of 11 demonstrable antigens in unheated culture filtrates of 12 vaccine strains of BCG were shared as determined in a reference antigen-antibody immunoelectrophoresis system. Filtrates from each of the BCG strains gave equivalent skin test reactions in homologously and heterologously sensitized guinea pigs. By these immunological parameters, the 12 BCG strains were remarkably similar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202960"} {"pmid": "4202956", "title": "Quantitative chemical composition of peptidoglycan of Listeria monocytogenes.", "content": "Quantitative chemical composition of peptidoglycan of Listeria monocytogenes. The qualitative and quantitative chemical composition of the peptidoglycan layer of Listeria monocytogenes cell walls was determined. The peptidoglycan layer was isolated from intact cells after treatment with sodium lauryl sulfate and digestion with Pronase. The isolated peptidoglycan contained carbohydrates which included hexose, rhamnose, and amino sugars. The amino sugar was identified as glucosamine which was present in very high micromole concentration, as compared with the amino acids, muramic acid, or diaminopimelic acid. In addition, protein and phosphorus were also present. However, the presence of teichoic acid was not detected in the peptidoglycan. Protein moiety contained a total of 18 amino acids with lysine as the N-terminal amino acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202956"} {"pmid": "4202958", "title": "Extracellular antigens from Listeria monocytogenes. II. Cytotoxicity of hemolytic and lipolytic antigens of Listeria for cultured mouse macrophages.", "content": "Extracellular antigens from Listeria monocytogenes. II. Cytotoxicity of hemolytic and lipolytic antigens of Listeria for cultured mouse macrophages. Purified preparations of hemolytic and lipolytic antigens were shown to be cytotoxic for tissue cultures of mouse peritoneal macrophage monolayers. The percent reduction in viability was proportional to the concentration of antigen used although, for a brief period, the hemolytic antigen stimulated the growth of cultured macrophages. Hemolytic and lipolytic antigens were synthesized by an hemolysin-producing strain (7973), but were deficient or totally lacking in nonhemolysin-producing strains (9037-7, 4219). The inoculation of strain 7973 onto macrophage monolayers at a bacterium to macrophage ratio of 10:1 resulted in a complete loss of viable phagocytic cells. The decrease in viable phagocytic cells was accompanied by an increase in viable listeria. Pronounced cytopathic activity with proliferation of listeria was also observed when 200 U of lipolytic antigen were added to macrophage monolayers that had been infected with the smooth type nonhemolysin-producing strain (4219) on the previous day. On the other hand, a high percentage of macrophages survived when exposed to nonhemolysin-producing strains only. In this case, listeria were not recovered by routine culture methods. The data presented do not establish that phagocytic cell destruction with accompanying microbial proliferation is the direct result of hemolysin elaboration; however, they suggest that there is need for further exploration of the role of the hemolysin in listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202958"} {"pmid": "4202959", "title": "Enzyme-linked immunosorbent assays for cholera serology.", "content": "Enzyme-linked immunosorbent assays for cholera serology. The enzyme-linked immunosorbent assay (ELISA) principle of Engvall and Perlmann, which employs antigen-coated tubes and enzyme-labeled anti-immunoglobulins, was elaborated for use in cholera serology. Immunoglobulin class-specific determinations of primary binding titers of antibodies to cholera exotoxin and endotoxin were more sensitive than were neutralization and vibriocidal tests. It was notable that rather high ELISA titers of immunoglobulin M (IgM) antibodies to exotoxin, which lacked neutralizing capacity were registered, whereas corresponding levels of immunoglobulin G (IgG) antibodies were effectively neutralizing. A modified technique permitting measurement of the binding rate of antibody to the solid-phase antigen was introduced as a possible tool for antibody avidity estimation. Such measurements indicated a wide avidity difference between the IgG and the IgM anti-exotoxin antibodies, which could explain their different neutralizing capacities. The observation that increasing binding rate of the IgG antibodies during the course of the primary immune response could compensate for decreasing antibody amount with regard to neutralizing capacity of serum also indicated the importance of antibody avidity for toxin neutralization. Inhibition with soluble antigen permitted quantitative determination of antigen; levels of exotoxin 0.09 mug/ml and of endotoxin to 1.3 mug/ml were measured.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202959"} {"pmid": "4202962", "title": "Thermography of tuberculin reactions in cattle.", "content": "Thermography of tuberculin reactions in cattle. The allergic reactions of dermal induration and hyperthermia were compared in tuberculin-hypersensitive calves. Tuberculins prepared from Mycobacterium avium, M. bovis, and M. paratuberculosis were administered intradermally and the responses were compared. The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared to contain elements of both immediate and delayed hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202962"} {"pmid": "4202965", "title": "Diffusion artifacts in cytochemistry of catalase.", "content": "Diffusion artifacts in cytochemistry of catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202965"} {"pmid": "4202961", "title": "Experimental induction of anergy to coccidioidin by antigens of Coccidioides immitis.", "content": "Experimental induction of anergy to coccidioidin by antigens of Coccidioides immitis. Failure to react to coccidioidin (anergy) often occurs in patients with disseminated coccidioidomycosis. One possible reason may be desensitization by excessive amounts of antigen. This was studied experimentally by injection of soluble and hyphal antigens of Coccidioides immitis into coccidioidin- and tuberculin-sensitive guinea pigs. Guinea pigs sensitized by injection of killed hyphal cells of C. immitis in complete Freund adjuvant were subsequently injected daily either with soluble coccidioidal antigen administered intraperitoneally or with hyphal antigen administered either subcutaneously or intraperitoneally. Gradual loss of cutaneous reactivity to coccidioidin occurred, but the reactivity to tuberculin remained unimpaired. The rapidity of desensitization was roughly proportional to the dose of antigen with desensitization occurring as early as 6 days after beginning injections. This anergic state was temporary, and reactivity returned several days after discontinuing injection of antigen. Injection of coccidioidal antigen led to production of coccidioidal complement-fixing antibody, but there was no consistent relationship between the antibody titer and state of cutaneous reactivity to coccidioidin. Peritoneal exudate or pulmonary alveolar cells from desensitized animals migrated freely in the presence of coccidioidin but were inhibited in the presence of tuberculin. Heat treatment did not impair the capacity of the soluble or hyphal antigen to induce anergy, thus suggesting that the antigen active in complement fixation was perhaps not involved in desensitization. Polysaccharide obtained by ethanol precipitation of dialyzed coccidioidin failed to induce anergy. Dialysis of the soluble coccidioidal antigen caused the loss of the desensitizing activity. Thus, specific desensitization could be induced by administration of large doses of coccidioidal antigen but dialyzable components appear important in this desensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202961"} {"pmid": "4202967", "title": "A steady state model of sequential irreversible enzyme reactions.", "content": "A steady state model of sequential irreversible enzyme reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202967"} {"pmid": "4202964", "title": "Possible transmission of serum (Australia-antigen-positive) hepatitis via the conjunctiva.", "content": "Possible transmission of serum (Australia-antigen-positive) hepatitis via the conjunctiva. A nursing sister developed Australia-antigen-positive hepatitis 101 days after the blood of an Australia-antigen-positive patient was accidentally introduced into her eye. There may be important implications for those caring for patients with Australia-antigenemia or undertaking laboratory investigations on their blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202964"} {"pmid": "4202963", "title": "Cytological localization of Dengue-2 antigens: an immunological study with ultrastructural correlation.", "content": "Cytological localization of Dengue-2 antigens: an immunological study with ultrastructural correlation. Immunofluorescence and electron microscopy were used to study the development and cytological distribution of dengue-2 virion and nonvirion antigens in monkey kidney cells. The type and combination of fixatives were found to affect the intensity of fluorescence. Paraformaldehyde fixation alone resulted in a low level of fluorescence, but an additional fixation step with ethanol or acetone resulted in maximum staining. No fluorescence was obtained after fixation with glutaraldehyde alone or in combination with other solvents. Methanol caused selective ablation of fluorescence by antibody to purified virions. Dengue-specific fluorescence that was most intense in the perinuclear area radiated in a granular pattern of decreasing intensity into the cytoplasm. The perinuclear fluorescence was associated with nonvirion antigens and the cytoplasmic fluorescence was associated with virion antigens. Electron micrographs of infected cells revealed vesicular bodies with reticular electron-dense centers, clusters of structurally complete virions deep within the endoplasmic reticulum, and single virus particles in vacuoles near the periphery of the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202963"} {"pmid": "4202968", "title": "Malnutrition and hepatitis-associated antigen infection.", "content": "Malnutrition and hepatitis-associated antigen infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202968"} {"pmid": "4202969", "title": "Infantile malnutrition and malabsorption.", "content": "Infantile malnutrition and malabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202969"} {"pmid": "4202970", "title": "Visual discordance cues induce prism adaptation in normal monkeys.", "content": "Visual discordance cues induce prism adaptation in normal monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202970"} {"pmid": "4202974", "title": "White blood cell acid hydrolases in leukaemias, mucopolysaccharidoses and mannosidosis.", "content": "White blood cell acid hydrolases in leukaemias, mucopolysaccharidoses and mannosidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202974"} {"pmid": "4202978", "title": "Maternal protein deprivation and toxemia of pregnancy: studies in the rhesus monkey (Macaca mulatta).", "content": "Maternal protein deprivation and toxemia of pregnancy: studies in the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202978"} {"pmid": "4202979", "title": "Prolactin secretion in sixty-five patients with galactorrhea.", "content": "Prolactin secretion in sixty-five patients with galactorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202979"} {"pmid": "4202980", "title": "Thiol solutions--inhibition of autoxidation.", "content": "Thiol solutions--inhibition of autoxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202980"} {"pmid": "4202981", "title": "Simplified methods for automated ion-exchange separation of peptides and accelerated manual Edman degradations.", "content": "Simplified methods for automated ion-exchange separation of peptides and accelerated manual Edman degradations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202981"} {"pmid": "4202984", "title": "Juvenile xanthogranuloma in a patient with Niemann-Pick disease.", "content": "Juvenile xanthogranuloma in a patient with Niemann-Pick disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202984"} {"pmid": "4202982", "title": "A spectrophotometric assay for Drosophila dopa decarboxylase.", "content": "A spectrophotometric assay for Drosophila dopa decarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202982"} {"pmid": "4202983", "title": "Comparative effects of dihydroergotamine and hydergin on the blood flow, capillary filtration rate and the capacitance vessels in the human calf studied by plethysmography.", "content": "Comparative effects of dihydroergotamine and hydergin on the blood flow, capillary filtration rate and the capacitance vessels in the human calf studied by plethysmography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202983"} {"pmid": "4202987", "title": "The relationship between progestins and gonadotropins during the late luteal phase of the menstrual cycle in rhesus monkeys.", "content": "The relationship between progestins and gonadotropins during the late luteal phase of the menstrual cycle in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202987"} {"pmid": "4202988", "title": "Thyrotropin-releasing hormone in the hypothalamus of the rat.", "content": "Thyrotropin-releasing hormone in the hypothalamus of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202988"} {"pmid": "4202989", "title": "Sexual maturation in the female rhesus monkey and the development of estrogen-induced gonadotropic hormone release.", "content": "Sexual maturation in the female rhesus monkey and the development of estrogen-induced gonadotropic hormone release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202989"} {"pmid": "4202991", "title": "Immunological techniques.", "content": "Immunological techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202991"} {"pmid": "4202990", "title": "Osmotic stimulation of vasotocin secretion by the toad's hypothalamo-neurohypophyseal system in vitro.", "content": "Osmotic stimulation of vasotocin secretion by the toad's hypothalamo-neurohypophyseal system in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202990"} {"pmid": "4202993", "title": "Effect of L-asparagine on growth of Mycobacterium tuberculosis and on utilization of other amino acids.", "content": "Effect of L-asparagine on growth of Mycobacterium tuberculosis and on utilization of other amino acids. l-Asparagine controls the utilization of other amino acids by Mycobacterium tuberculosis (H37Ra) in aerated, liquid synthetic media. In a mixture containing asparagine and either l-alanine or l-glutamic acid, amino acid utilization is diphasic, with asparagine being utilized first. Short-term growth rates and cell yields are diminished and mimic those seen with asparagine alone. Catabolite repression is the probable regulatory mechanism responsible for this effect of asparagine. In contrast, in the presence of aspartic acid, asparagine stimulates growth and increases utilization of aspartic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202993"} {"pmid": "4202992", "title": "Absence of 3'-terminal residues from transfer ribonucleic acid of dormant spores of Bacillus megaterium.", "content": "Absence of 3'-terminal residues from transfer ribonucleic acid of dormant spores of Bacillus megaterium. Essentially all (>97%) of the transfer ribonucleic acid (tRNA) in log-phase and sporulating cells of Bacillus megaterium contains a complete 3'-cytidyl-cytidyl-adenosine terminus. However, about one-third of the tRNA in the dormant spore lacks the 3'-terminal adenosine 5'-monophosphate (AMP) residue, and some of the adjacent cytosine monophosphate residues are also missing. Examination of specific tRNAs indicated that those specific for isoleucine, leucine, and methionine are missing 30 to 40% of their terminal residue, whereas tRNAs specific for tyrosine lack 88% of the 3'-terminal AMP. Defective spore tRNA is not degraded during germination, but the missing residues are added back in the first minutes of the process. The enzyme catalyzing the addition reaction, tRNA nucleotidyltransferase, is present in the dormant spore at a level similar to that found in the vegetative cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202992"} {"pmid": "4202994", "title": "Effect of helium gas at elevated pressure on iron transport and growth of Escherichia coli.", "content": "Effect of helium gas at elevated pressure on iron transport and growth of Escherichia coli. Helium at an ambient pressure of 68 at m with 0.2 atm of O(2) shortened by 1 to 1.5 h the lag phase for growth of Escherichia coli in minimal medium supplemented with 2 muliters of cell-free culture filtrate (CFF) per ml or with 1 muM 2,3-dihydroxybenzoylserine (DHBS), an iron chelator. The lag phase of cultures not exposed to helium could be shortened by use of supplements, but higher concentrations were required-10 to 30 muliters of CFF per ml or 10 to 50 muM DHBS. Strain AN 193 of E. coli, which requires the DHBS precursor 2,3-dihydroxybenzoic acid (DHBA), grew well in media with 10 muM DHBA when exposed to helium at 68 atm, whereas 100 muM DHBA was required for growth in unexposed cultures. In the presence of 100 muM DHBA plus 1.0 muM ethylenediaminetetraactic acid, growth was inhibited at 1 and 68 atm. Growth was restored, however, by the addition of 0.1 muM FeSO(4) at 68 atm and 1.0 muM FeSO(4) at 1 atm, but lag times were invariably shorter in the pressurized cultures. Hydrostatic pressures of 68 atm did not reduce the lag phase in the presence of CFF, DHBS, or DHBA. Our results suggest that 68 atm of helium pressure, but not hydrostatic pressure, elicited a more rapid transport of iron into the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202994"} {"pmid": "4202995", "title": "Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance.", "content": "Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance. Three plasmids designated alpha, beta, and gamma, distinguishable by their molecular weights (6, 17, and 34 million, respectively) were isolated from Streptococcus faecalis strain DS-5 (ATCC 14508). Derivatives of this strain \"cured\" for erythromycin resistance lacked the beta-plasmid. In the parent strain the beta-plasmid was estimated to be present to the extent of one to two copies per chromosomal genome equivalent whereas the alpha- and gamma-plasmids were about nine and five copies, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202995"} {"pmid": "4202997", "title": "Phenotype recognition of pyocyanine mutants in pseudomonas aeruginosa.", "content": "Phenotype recognition of pyocyanine mutants in pseudomonas aeruginosa. Certain classes of pyocyanine mutants in Pseudomonas aeruginosa escape detection when screened in the presence of wild-type or other mutant cells. A technique is described for recognizing mutant phenotypes after cells are in individual agar wells. The procedure eliminates cross-feeding phenomena as well as the masking of mutant phenotypes by diffusing pyocyanine produced by nearby clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202997"} {"pmid": "4202996", "title": "Ultrastructural and chemical alteration of the cell envelope of Pseudomonas aeruginosa, associated with resistance to ethylenediaminetetraacetate resulting from growth in a Mg2+-deficient medium.", "content": "Ultrastructural and chemical alteration of the cell envelope of Pseudomonas aeruginosa, associated with resistance to ethylenediaminetetraacetate resulting from growth in a Mg2+-deficient medium. Cells of Pseudomonas aeruginosa became resistant to the lytic effect of ethylenediametetraacetate (EDTA) when grown in a Mg(2+)-deficient medium. To correlate ultrastructural changes in the cell wall associated with the shift to EDTA-resistance, a freeze-etch study was performed. Upon fracturing, the outer cell wall membrane split down the hydrophobic center to reveal the outer (concave) and inner (convex) layers. The concave cell wall layer of EDTA-sensitive cells grown in Mg(2+)-sufficient medium contained spherical units resting on an underlying smooth support layer. Upon EDTA treatment, approximately one-half of these spherical units were extracted. Cells grown in Mg(2+)-deficient medium were resistant to EDTA. The concave cell wall layer of EDTA-resistant cells had increased numbers of highly compacted spherical units, giving this layer a disorganized appearance. The highly compacted appearance of this layer was unaltered by EDTA treatment. Thus, growth in Mg(2+)-deficient medium resulted in cells which were resistant to EDTA and which possessed an ultrastructurally altered outer layer of the outer cell wall membrane. Cell envelopes from EDTA-resistant cells were found to possess 18% less phosphorus, 16.4% more total carbohydrate, and 13.3% more 2-keto-3-deoxyoctonate than cell envelopes from EDTA-sensitive cells. There were also qualitative, but not quantitative, differences in the protein content of cell envelopes from EDTA-resistant and EDTA-sensitive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202996"} {"pmid": "4202998", "title": "Mapping of the 5-methyltryptophan resistance locus in Bacillus subtilis.", "content": "Mapping of the 5-methyltryptophan resistance locus in Bacillus subtilis. The 5-methyltryptophan resistance locus (mtr) in Bacillus subtilis, which leads to constitutive production of the tryptophan enzymes, has been mapped on the chromosome. The order of loci is ser-1-mtr-aroF-aroB-trp-hisB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202998"} {"pmid": "4202999", "title": "Changes in menaquinone concentration during growth and early sporulation in Bacillus subtilis.", "content": "Changes in menaquinone concentration during growth and early sporulation in Bacillus subtilis. In two strains of Bacillus subtilis, menaquinone-7 has been shown to reach maximal cellular concentrations during early stationary phase. These concentration changes closely parallel the previously reported concentration changes in the cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4202999"} {"pmid": "4203001", "title": "Pneumothorax complicating continuous ventilatory support.", "content": "Pneumothorax complicating continuous ventilatory support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203001"} {"pmid": "4203000", "title": "Characterization of the antigenic subunits of the envelope protein of Yersinia pestis.", "content": "Characterization of the antigenic subunits of the envelope protein of Yersinia pestis. Chemical, physical, and immunological properties of the envelope antigen of Yersinia pestis strains have been investigated. The antigen consists of two components with isoelectric points (pI) of 4.6 and 4.8. One component (pI 4.6) is a protein bound to a small carbohydrate moiety identified as an oligomeric galactan; the other component (pI 4.8) is a simple protein. These two components are antigenically identical. In buffered solution, the antigen exists as aggregates of molecular weights larger than 300,000. The aggregates dissociate into a variety of smaller molecular weight forms depending on the nature of the treatment for dissociation. Each aggregate can be further dissociated into a single antigenic subunit fraction containing protein and glycoprotein species with molecular weights in the range from 15,000 to 17,000. The subunits can be obtained by a dissociation treatment with 0.1% mercaptoethanol in 0.25% sodium dodecyl sulfate at 95 C for 5 min. The subunits will readily reaggregate into a variety of larger molecular weight forms on the removal of dodecyl sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203000"} {"pmid": "4203004", "title": "Some quantitative aspects of in vitro thyroid diagnostic tests.", "content": "Some quantitative aspects of in vitro thyroid diagnostic tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203004"} {"pmid": "4203006", "title": "Occult blood detection in faeces of various animal species.", "content": "Occult blood detection in faeces of various animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203006"} {"pmid": "4203007", "title": "Impaired lymphocyte function in untreated Hodgkin's disease.", "content": "Impaired lymphocyte function in untreated Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203007"} {"pmid": "4203008", "title": "Letter: Statistical analysis of treatment with vitamin E.", "content": "Letter: Statistical analysis of treatment with vitamin E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203008"} {"pmid": "4203010", "title": "Letter: Urinary sphingomyelin in Niemann-Pick disease.", "content": "Letter: Urinary sphingomyelin in Niemann-Pick disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203010"} {"pmid": "4203011", "title": "Letter: Chagas's disease--another hazard in acute leukemia.", "content": "Letter: Chagas's disease--another hazard in acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203011"} {"pmid": "4203009", "title": "Treatment of disseminated gonococcal infection. A prospective evaluation of short-term antibiotic therapy.", "content": "Treatment of disseminated gonococcal infection. A prospective evaluation of short-term antibiotic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203009"} {"pmid": "4203012", "title": "Survival of common bacteria in liquid culture under carbon dioxide at high temperatures.", "content": "Survival of common bacteria in liquid culture under carbon dioxide at high temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203012"} {"pmid": "4203013", "title": "Understanding cerebrovascular function. Contributions of space techniques.", "content": "Understanding cerebrovascular function. Contributions of space techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203013"} {"pmid": "4203014", "title": "Microbial flora found in the products of conception in spontaneous abortions.", "content": "Microbial flora found in the products of conception in spontaneous abortions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203014"} {"pmid": "4203015", "title": "Blood disappearance rates of certain hormones and enzymes advocated as fetoplacental function tests.", "content": "Blood disappearance rates of certain hormones and enzymes advocated as fetoplacental function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203015"} {"pmid": "4203016", "title": "Congenital tuberculosis.", "content": "Congenital tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203016"} {"pmid": "4203017", "title": "Proceedings: Medullary carcinoma of the thyroid gland.", "content": "Proceedings: Medullary carcinoma of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203017"} {"pmid": "4203020", "title": "Proceedings: The cost of cancer.", "content": "Proceedings: The cost of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203020"} {"pmid": "4203019", "title": "Proceedings: Megavoltage irradiation for bladder cancer: alone, postoperative, or preoperative?", "content": "Proceedings: Megavoltage irradiation for bladder cancer: alone, postoperative, or preoperative?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203019"} {"pmid": "4203018", "title": "Proceedings: The role of radiation therapy in the management of patients with carcinoma of the rectum and rectosigmoid.", "content": "Proceedings: The role of radiation therapy in the management of patients with carcinoma of the rectum and rectosigmoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203018"} {"pmid": "4203021", "title": "Proceedings: The role of radiation therapy in the treatment of soft-tissue sarcoma in adults.", "content": "Proceedings: The role of radiation therapy in the treatment of soft-tissue sarcoma in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203021"} {"pmid": "4203022", "title": "Neurons in rhesus monkey visual cortex: systematic relation between time of origin and eventual disposition.", "content": "Neurons in rhesus monkey visual cortex: systematic relation between time of origin and eventual disposition. Autoradiographic evidence after injection of tritiated thymidine indicates that cell position in the laminae of the monkey visual cortex is systematically related to time of cell orgin. The earliest-formed neurons, destined for the deepest stratum, arise at about embryonic day 45, and the last ones, destined for the outermost cell stratum, form at about day 102; cells of intervening layers are generated at intervening times. No neocortical neurons are produced in the last two prenatal months or after birth. Compared to cortical neurons in rodents, those in the monkey arise earlier, and the \"inside-out\" relation of cell position to time of origin is more rigid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203022"} {"pmid": "4203023", "title": "Deuterium oxide effect on temperature-dependent survival in populations of Drosophila melanogaster.", "content": "Deuterium oxide effect on temperature-dependent survival in populations of Drosophila melanogaster. A comparison of the mean life-spans for populations of Drosophila melanogaster at 10 degrees , 20 degrees , 25 degrees , and 30 degrees C maintained on media prepared with distilled water and with 50 percent deuterium oxide shows that deuteration decreases longevity at all four temperatures. The magnitude of the difference between the mean survival times of populations maintained on deuterated and nondeuterated media is inversely related to temperature between 10 degrees and 30 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203023"} {"pmid": "4203024", "title": "Carbonic anhydrase and osteoclasts: localization by labeled inhibitor autoradiography.", "content": "Carbonic anhydrase and osteoclasts: localization by labeled inhibitor autoradiography. Autoradiography with tritiated acetazolamide indicates that osteoclasts of the hen and chick contain concentrations of carbonic anhydrase which are similar to those in pancreatic acinar cells. Grain counts of osteoblasts and osteocytes were not different from background. Thus, a sufficient quantity of carbonic anhydrase seems to be present in osteoclasts to be of physiological importance in bone resorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203024"} {"pmid": "4203025", "title": "Calcium ion release in mechanically disrupted heart cells.", "content": "Calcium ion release in mechanically disrupted heart cells. In cardiac muscle fibers which have had their sarcolemma disrupted intracellular stores of calcium ions can be released by the same chemical stimuli which cause their release from the sarcoplasmic reticulum of skinned skeletal muscle fibers. These stimuli are increases in calcium or caffeine concentrations and substitution of chloride for propionate or sodium for potassium in solutions bathing the fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203025"} {"pmid": "4203026", "title": "Management of the nephrotic syndrome.", "content": "Management of the nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203026"} {"pmid": "4203028", "title": "Salivatory fibres in the trigeminal part of the lingual nerve to the mandibular salivary gland of the monkey.", "content": "Salivatory fibres in the trigeminal part of the lingual nerve to the mandibular salivary gland of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203028"} {"pmid": "4203029", "title": "A new approach to the synthesis of oligodeoxyribonucleotides.", "content": "A new approach to the synthesis of oligodeoxyribonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203029"} {"pmid": "4203030", "title": "Evaluation of heterologous vascular grafts as small vessel substitutes.", "content": "Evaluation of heterologous vascular grafts as small vessel substitutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203030"} {"pmid": "4203031", "title": "Physical measurements of medical electron beams--a review.", "content": "Physical measurements of medical electron beams--a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203031"} {"pmid": "4203032", "title": "Fibroblast surface antigen: a new serum protein.", "content": "Fibroblast surface antigen: a new serum protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203032"} {"pmid": "4203034", "title": "Studies on the control of some simple motor tasks. 3. Comparison of the EMG pattern during ballistically initiated movements in man and squirrel monkey.", "content": "Studies on the control of some simple motor tasks. 3. Comparison of the EMG pattern during ballistically initiated movements in man and squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203034"} {"pmid": "4203033", "title": "Neuronal migration, with special reference to developing human brain: a review.", "content": "Neuronal migration, with special reference to developing human brain: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203033"} {"pmid": "4203027", "title": "Acute stroke management and patient outcome: the value of Neurovascular Care Units (NCU).", "content": "Acute stroke management and patient outcome: the value of Neurovascular Care Units (NCU).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203027"} {"pmid": "4203035", "title": "Studies on the control of some simple motor tasks. IV. Relation between parameters of motion and motor output in squirrel monkey.", "content": "Studies on the control of some simple motor tasks. IV. Relation between parameters of motion and motor output in squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203035"} {"pmid": "4203036", "title": "Responses of small myelinated \"warm\" fibers to noxious heat stimuli applied to the monkey's face.", "content": "Responses of small myelinated \"warm\" fibers to noxious heat stimuli applied to the monkey's face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203036"} {"pmid": "4203037", "title": "Visual discrimination deficits associated with posterior inferotemporal lesions in the monkey.", "content": "Visual discrimination deficits associated with posterior inferotemporal lesions in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203037"} {"pmid": "4203038", "title": "Operable breast cancer: the case against conservative surgery.", "content": "Operable breast cancer: the case against conservative surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203038"} {"pmid": "4203039", "title": "Operable breast cancer: in defense of conservative surgery.", "content": "Operable breast cancer: in defense of conservative surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203039"} {"pmid": "4203041", "title": "Colon and rectal lesions: a tutorendoscopic view.", "content": "Colon and rectal lesions: a tutorendoscopic view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203041"} {"pmid": "4203040", "title": "Features suggesting curability in lymphoma and leukemia.", "content": "Features suggesting curability in lymphoma and leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203040"} {"pmid": "4203060", "title": "Phenotypic variation in the popliteal pterygium syndrome.", "content": "Phenotypic variation in the popliteal pterygium syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203060"} {"pmid": "4203061", "title": "Mass screening newborns for mucopolysaccharidoses.", "content": "Mass screening newborns for mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203061"} {"pmid": "4203062", "title": "Assays for cellular antigens in the presence of detergents.", "content": "Assays for cellular antigens in the presence of detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203062"} {"pmid": "4203063", "title": "Homogeneity of antibodies produced by clones in vitro.", "content": "Homogeneity of antibodies produced by clones in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203063"} {"pmid": "4203064", "title": "Antibody response, measured by a plaque assay, compared to cellular response after skin allograft in mice.", "content": "Antibody response, measured by a plaque assay, compared to cellular response after skin allograft in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203064"} {"pmid": "4203065", "title": "Carbon dioxide production from pyruvate and glucose by bovine oocytes.", "content": "Carbon dioxide production from pyruvate and glucose by bovine oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203065"} {"pmid": "4203066", "title": "Protein incorporation by isolated amphibian oocytes. IV. The role of follicle cells and calcium during protein uptake.", "content": "Protein incorporation by isolated amphibian oocytes. IV. The role of follicle cells and calcium during protein uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203066"} {"pmid": "4203067", "title": "Lysosomal enzymes in relation to the isoproterenol-induced secretory cycle in rat parotid gland.", "content": "Lysosomal enzymes in relation to the isoproterenol-induced secretory cycle in rat parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203067"} {"pmid": "4203068", "title": "Ontogeny of gamma-crystallin in the chick lens.", "content": "Ontogeny of gamma-crystallin in the chick lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203068"} {"pmid": "4203069", "title": "Proceedings: Anatomy and pathophysiology of ocular circulation.", "content": "Proceedings: Anatomy and pathophysiology of ocular circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203069"} {"pmid": "4203070", "title": "Proceedings: Studies on retinal blood flow regulation: the effect of PaCO2 on blood flow, oxygen availability, oxygen consumption rate and ERG in monkeys.", "content": "Proceedings: Studies on retinal blood flow regulation: the effect of PaCO2 on blood flow, oxygen availability, oxygen consumption rate and ERG in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203070"} {"pmid": "4203071", "title": "Proceedings: A comparison of some derivatives of phloretin as prostaglandin antagonists.", "content": "Proceedings: A comparison of some derivatives of phloretin as prostaglandin antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203071"} {"pmid": "4203072", "title": "Proceedings: The effect of increased intraocular pressure on the endothelium of Schlemm's canal.", "content": "Proceedings: The effect of increased intraocular pressure on the endothelium of Schlemm's canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203072"} {"pmid": "4203073", "title": "Proceedings: Experimental iris suture in primates.", "content": "Proceedings: Experimental iris suture in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203073"} {"pmid": "4203074", "title": "Unequivocal identification of sphingomyelin in the lipids of Tetrahymena pyriformis.", "content": "Unequivocal identification of sphingomyelin in the lipids of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203074"} {"pmid": "4203075", "title": "Behavioral effects of tularemia and sandfly fever in man.", "content": "Behavioral effects of tularemia and sandfly fever in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203075"} {"pmid": "4203076", "title": "Interaction of lipopolysaccharides with mitochondria. II. Effects of magnesium ions on toxicity of a rough lipopolysaccharide.", "content": "Interaction of lipopolysaccharides with mitochondria. II. Effects of magnesium ions on toxicity of a rough lipopolysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203076"} {"pmid": "4203077", "title": "Immune response of the human respiratory tract. II. Cell-mediated immunity in the lower respiratory tract to tuberculin and mumps and influenza viruses.", "content": "Immune response of the human respiratory tract. II. Cell-mediated immunity in the lower respiratory tract to tuberculin and mumps and influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203077"} {"pmid": "4203079", "title": "Growth of measles virus in the lymphoid tissues of monkeys.", "content": "Growth of measles virus in the lymphoid tissues of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203079"} {"pmid": "4203078", "title": "Immunogenicity of group A and group C meningococcal polysaccharides in human infants.", "content": "Immunogenicity of group A and group C meningococcal polysaccharides in human infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203078"} {"pmid": "4203080", "title": "Inhibition of DNA and protein synthesis in melanocytes by a melanoma extract.", "content": "Inhibition of DNA and protein synthesis in melanocytes by a melanoma extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203080"} {"pmid": "4203081", "title": "Pancreatic-type tissue in livers of rats fed polychlorinated biphenyls.", "content": "Pancreatic-type tissue in livers of rats fed polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203081"} {"pmid": "4203082", "title": "Replication of bacteriophage SH-133 in the facultative autotroph Hydrogenomonas facilis. I. Bacteriophage synthesis under heterotrophic, autotrophic, and mixotrophic growth conditions.", "content": "Replication of bacteriophage SH-133 in the facultative autotroph Hydrogenomonas facilis. I. Bacteriophage synthesis under heterotrophic, autotrophic, and mixotrophic growth conditions. The ability of bacteriophage SH-133 to replicate in heterotrophically (H-) and autotrophically (A-) grown Hydrogenomonas facilis was examined. Both the synthesis of infectious phage particles and the efficiency of plating (EOP) were reduced by 90% in A-grown cells. Adsorption of phage and lethal effects on H. facilis were identical in both systems. One-step growth experiments showed that cell lysis preceded the appearance of infectious particles in A-grown cells. Burst size studies with mixotrophically grown cells did not indicate the presence of an inhibitor of phage synthesis indigenous to autotrophic metabolism. DNA synthesis was identical in H- and A-grown infected cells; however, protein synthesis was significantly reduced in A-grown infected cells when compared with protein synthesis in H-grown infected cells. The data suggest that the reduction in EOP and phage synthesis in A-grown cells is caused by a defect in viral protein synthesis which results in the limited production of an essential viral protein at the time of cell lysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203082"} {"pmid": "4203083", "title": "Synthesis of the unusual DNA of Bacillus subtilis bacteriophage SP-15.", "content": "Synthesis of the unusual DNA of Bacillus subtilis bacteriophage SP-15. Cultures of Bacillus subtilis infected with phage SP-15 were examined to investigate the metabolic origin of two of the unique components of the phage DNA: the component responsible for the unusually high buoyant density in CsCl and the unusual pyrimidine, 5-(4', 5'-dihydroxypentyl) uracil (DHPU). Newly synthesized pulse-labeled DNA was light in buoyant density and shifted to the high density of mature phage DNA upon further incubation. Parental DNA was converted to a light-density intermediate form prior to replication. When labeled uracil, thymidine, or DHPU were added to infected cells, it was found that only uracil served as the precursor to DHPU and thymine in phage DNA. Analysis of the bases from hydrolyzed DNA of labeled phage or infected cells indicated that the uracil was incorporated into the DNA as such (presumably via deoxyuridine triphosphate) and later converted to DHPU and thymine at the macromolecular level. The sequence of events after phage infection appeared to be: (i) injection of parental DNA; (ii) conversion of parental DNA to a light form; (iii) DNA replication, yielding light DNA containing uracil; (iv) conversion of uracil to DHPU and thymine; and (v) addition of the heavy component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203083"} {"pmid": "4203084", "title": "Replication of bacteriophage SH-133 in the facultative autotroph Hydrogenomonas facilis. II. Bacteriophage synthesis and hydrogenase induction under step-up and step-down growth conditions.", "content": "Replication of bacteriophage SH-133 in the facultative autotroph Hydrogenomonas facilis. II. Bacteriophage synthesis and hydrogenase induction under step-up and step-down growth conditions. Autotrophically grown infected cells are able to replicate phage SH-133 after being switched to a heterotrophic environment (step-up growth). The effect of step-down growth on phage replication varies with the choice of organic substrate. Phage replication and the induction of cellular hydrogenase occur under step-down growth from acetate but not peptone broth. The requirement of a continued source of energy for phage replication in either heterotrophically or autotrophically grown cells could be uniquely demonstrated in this phage-host system by the deletion of hydrogen from the growth medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203084"} {"pmid": "4203085", "title": "Viral protein synthesis in bacteriophage phi 29-infected Bacillus subtilis.", "content": "Viral protein synthesis in bacteriophage phi 29-infected Bacillus subtilis. Twenty-three (14)C-labeled phage phi29-specific proteins in lysates of UV-irradiated Bacillus subtilis have been resolved by sodium dodecyl sulfate polyacrylamide gel electrophoresis and identified by autoradiography. Included in this group of proteins are the six major structural proteins of the virion. Analysis of the temporal sequence of viral protein synthesis indicates that three groups of proteins can be identified by time of appearance, beginning at 2 to 4, 4 to 6, or 8 to 10 min after infection, respectively. These proteins account for approximately 90% of the coding capacity of the phi29 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203085"} {"pmid": "4203086", "title": "Isolation and characterization of a bacteriophage for Thiobacillus novellus.", "content": "Isolation and characterization of a bacteriophage for Thiobacillus novellus. A DNA-containing bacteriophage for Thiobacillus novellus has been isolated from sewage and purified by ammonium sulfate precipitation, differential centrifugation, and cesium chloride equilibrium centrifugation. The buoyant density of this phage in CsCl is 1.51 g/cm(3). Electron microscopy studies have revealed a polyhedral head about 60 nm in diameter and a tail surrounded by a number of fine filaments. It has an adsorption rate constant of 1.1 x 10(-9) ml/min, a latent period of 45 min, and an average burst size of 150. The mole guanine and cytosine content in its DNA has been estimated to be 57 to 58%. Five structural proteins with molecular weights of 62,000, 42,500, 30,500, 17,750, and 13,500 have been detected by polyacrylamide gel electrophoresis techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203086"} {"pmid": "4203087", "title": "Characterization of virus-specific RNAs from subacute sclerosing panencephalitis virus-infected CV-1 cells.", "content": "Characterization of virus-specific RNAs from subacute sclerosing panencephalitis virus-infected CV-1 cells. CV-1 cells infected with subacute sclerosing panencephalitis (SSPE) virus incorporated uridine-(3)H into at least four virus-specific RNA components in the presence of actinomycin D. The component sedimenting fastest had a sedimentation coefficient of 50s corresponding to a molecular weight of 6 x 10(6). The other three RNA components have sedimentation constants of 35s, 22s, and 18s corresponding to molecular weights of 2.5 x 10(6), 1.0 x 10(6), and 0.75 x 10(6), respectively. The base composition of the 50s RNA is distinct from that of cellular RNA and comparable with base compositions of viral RNAs of other paramyxoviruses. The base composition of the 18s RNA shows approximate complementarity with the 50s RNA. RNA-RNA annealing experiments using unlabeled 50s SSPE RNA with labeled 18s RNA from cells infected with SSPE virus or measles virus show 100% annealing with 18s SSPE RNA but only 60% annealing with 18s measles RNA. These experiments suggest some differences between the 18s RNAs of SSPE virus-infected cells and measles virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203087"} {"pmid": "4203088", "title": "Triiodothyronine. Physiological and clinical significance.", "content": "Triiodothyronine. Physiological and clinical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203088"} {"pmid": "4203089", "title": "Letter: Jet lag ketoacidosis.", "content": "Letter: Jet lag ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203089"} {"pmid": "4203090", "title": "Intracellular components associated with Chikungunya virus-specific ribonucleic acids in infected BHK21 cells.", "content": "Intracellular components associated with Chikungunya virus-specific ribonucleic acids in infected BHK21 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203090"} {"pmid": "4203092", "title": "Studies on murine leprosy bacillus. VII. Temperature range and temperature optimum for the growth of the supposed murine leprosy bacillus.", "content": "Studies on murine leprosy bacillus. VII. Temperature range and temperature optimum for the growth of the supposed murine leprosy bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203092"} {"pmid": "4203091", "title": "FP5 factor, an undescribed sex factor of Pseudomonas aeruginosa.", "content": "FP5 factor, an undescribed sex factor of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203091"} {"pmid": "4203094", "title": "Control of infections from intravenous infusions.", "content": "Control of infections from intravenous infusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203094"} {"pmid": "4203098", "title": "Immunological characterization of anti-haemophilic factor A related antigen in haemophilia A.", "content": "Immunological characterization of anti-haemophilic factor A related antigen in haemophilia A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203098"} {"pmid": "4203100", "title": "Failure to thrive, in Lebanon. II. An investigation of the causes.", "content": "Failure to thrive, in Lebanon. II. An investigation of the causes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203100"} {"pmid": "4203101", "title": "Determination of glomerular filtration rate in the newborn. Comparison between results obtained by the single injection technique without collection of urine and the standard clearance technique.", "content": "Determination of glomerular filtration rate in the newborn. Comparison between results obtained by the single injection technique without collection of urine and the standard clearance technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203101"} {"pmid": "4203103", "title": "Effect of fasting and of a protein free diet on amino acid ratios in plasma and erythrocytes in rats.", "content": "Effect of fasting and of a protein free diet on amino acid ratios in plasma and erythrocytes in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203103"} {"pmid": "4203102", "title": "Diagnostic significance of serum orosomucoid level in bacterial infections during neonatal period.", "content": "Diagnostic significance of serum orosomucoid level in bacterial infections during neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203102"} {"pmid": "4203104", "title": "Safety aspects on long-term medication.", "content": "Safety aspects on long-term medication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203104"} {"pmid": "4203105", "title": "Generalized mucormycosis in the golden-bellied mangabey (Cercocebus galeritus chrysogaster, Lydekker).", "content": "Generalized mucormycosis in the golden-bellied mangabey (Cercocebus galeritus chrysogaster, Lydekker).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203105"} {"pmid": "4203108", "title": "Pathological findings on animals in the Royal Zoological Gardens of the Rotterdam Zoo during the years 1963, 1964 and 1965.", "content": "Pathological findings on animals in the Royal Zoological Gardens of the Rotterdam Zoo during the years 1963, 1964 and 1965.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203108"} {"pmid": "4203109", "title": "A method for determination of the synthesis rate of stable and unstable ribonucleic acid in Escherichia coli.", "content": "A method for determination of the synthesis rate of stable and unstable ribonucleic acid in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203109"} {"pmid": "4203110", "title": "Therapeutic implications of copper deficiency in Menkes's steely-hair syndrome.", "content": "Therapeutic implications of copper deficiency in Menkes's steely-hair syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203110"} {"pmid": "4203115", "title": "Kinetics of beta-lactamase inactivation of penicillins. II. Effect of competitive inhibitors.", "content": "Kinetics of beta-lactamase inactivation of penicillins. II. Effect of competitive inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203115"} {"pmid": "4203128", "title": "Cryoglobulinaemia in tropical splenomegaly syndrome.", "content": "Cryoglobulinaemia in tropical splenomegaly syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203128"} {"pmid": "4203129", "title": "Determination of IgG antiglobulins in rheumatoid disease using insolubilized human IgG.", "content": "Determination of IgG antiglobulins in rheumatoid disease using insolubilized human IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203129"} {"pmid": "4203130", "title": "Carcino embryonic antigens (CEA) and non-specific cross-reacting antigens in feces.", "content": "Carcino embryonic antigens (CEA) and non-specific cross-reacting antigens in feces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203130"} {"pmid": "4203131", "title": "Regional hemodynamic effects of dopamine in the unanesthetized primate: failure to alter flow-dependent hepatic drug clearance.", "content": "Regional hemodynamic effects of dopamine in the unanesthetized primate: failure to alter flow-dependent hepatic drug clearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203131"} {"pmid": "4203132", "title": "Evaluation of plasma thyrotrophin response to thyrotrophin releasing hormone in Graves' disease and in hyperactive thyroid adenoma before and after treatment.", "content": "Evaluation of plasma thyrotrophin response to thyrotrophin releasing hormone in Graves' disease and in hyperactive thyroid adenoma before and after treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203132"} {"pmid": "4203137", "title": "Effects of intense auditory stimulation: hearing losses and inner ear changes in the squirrel monkey. II.", "content": "Effects of intense auditory stimulation: hearing losses and inner ear changes in the squirrel monkey. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203137"} {"pmid": "4203136", "title": "Prevention of periodontal disease--a pathologist's view.", "content": "Prevention of periodontal disease--a pathologist's view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203136"} {"pmid": "4203139", "title": "Production of anti-idiotypic and anti-class specific antibody using micro amounts of myeloma serum.", "content": "Production of anti-idiotypic and anti-class specific antibody using micro amounts of myeloma serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203139"} {"pmid": "4203138", "title": "Primate head restrainer using a nonsurgical technique.", "content": "Primate head restrainer using a nonsurgical technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203138"} {"pmid": "4203140", "title": "N-alkylnorketobemidones with strong agonist and weak antagonist properties.", "content": "N-alkylnorketobemidones with strong agonist and weak antagonist properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203140"} {"pmid": "4203142", "title": "Synthetic trypanocides. 3. Structure-activity relationships.", "content": "Synthetic trypanocides. 3. Structure-activity relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203142"} {"pmid": "4203141", "title": "Thiourea derivatives of 2-aminooxazoles showing antibacterial and antifungal activity.", "content": "Thiourea derivatives of 2-aminooxazoles showing antibacterial and antifungal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203141"} {"pmid": "4203143", "title": "Calcium and phosphorus homeostasis in horses.", "content": "Calcium and phosphorus homeostasis in horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203143"} {"pmid": "4203145", "title": "Haematological relationships between New Guinean mothers and their infants.", "content": "Haematological relationships between New Guinean mothers and their infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203145"} {"pmid": "4203144", "title": "Effect of carbohydrate load by intravenous infusion in fasted rats on liver glucose-6-phosphate dehydrogenase and malic enzyme.", "content": "Effect of carbohydrate load by intravenous infusion in fasted rats on liver glucose-6-phosphate dehydrogenase and malic enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203144"} {"pmid": "4203146", "title": "Fatal cerebral oedema with insulitis in diabetic ketoacidosis.", "content": "Fatal cerebral oedema with insulitis in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203146"} {"pmid": "4203150", "title": "Effect of glutaraldehyde fixation on erythrocyte agglutinability.", "content": "Effect of glutaraldehyde fixation on erythrocyte agglutinability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203150"} {"pmid": "4203151", "title": "Relation between bacteriocin production and virulence of Streptococcus faecalis var. liquefaciens.", "content": "Relation between bacteriocin production and virulence of Streptococcus faecalis var. liquefaciens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203151"} {"pmid": "4203152", "title": "Effect of chorionic gonadotropin on corpus luteum of the monkey.", "content": "Effect of chorionic gonadotropin on corpus luteum of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203152"} {"pmid": "4203153", "title": "The isolation of mutants of Aspergillus flavus and A.parasiticus with altered aflatoxin producing ability.", "content": "The isolation of mutants of Aspergillus flavus and A.parasiticus with altered aflatoxin producing ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203153"} {"pmid": "4203154", "title": "Pathogenic effects of Cladosporium herbarum and Penicillium decumbens.", "content": "Pathogenic effects of Cladosporium herbarum and Penicillium decumbens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203154"} {"pmid": "4203157", "title": "Some aspects of intracellular parasitism.", "content": "Some aspects of intracellular parasitism. In intracellular parasitism the host cell is a true and hospitable host. The parasite does not have to break in the door. It has subtle ways of inducing the host to open the door and welcome it in. One of the exciting fields in the future of parasitology is to find out what these ways are and why they are sometimes so highly specific that the cell that invites one parasite in will not open the door to another closely related species. Once inside, the parasite not only exploits nutrients already available in the cell, and the cell's energy-yielding system, but it further induces the cell to assist actively in its nutrition. Like a bandit who has cajoled his way in, the parasite now forces his host to prepare a banquet for him. Finally it may destroy its host cell, as in most of the associations I have described herein, or it may stimulate its host cell to abnormal increase in size or to have an altered metabolism with the formation of new products. Or it may even contribute some positive benefit to the host cell or to the multicellular organism of which the cell is a part, so that the two kinds of organisms then live together in a state of mutualism or symbiosis (26).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203157"} {"pmid": "4203158", "title": "Progress of tuberculous diabetes coming under supervision during the years 1953-65 up to July 1972.", "content": "Progress of tuberculous diabetes coming under supervision during the years 1953-65 up to July 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203158"} {"pmid": "4203159", "title": "Drug resistant pulmonary tuberculosis treated with ethambutol and rifampicin in North East England.", "content": "Drug resistant pulmonary tuberculosis treated with ethambutol and rifampicin in North East England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203159"} {"pmid": "4203160", "title": "The differential tuberculin test in a BCG vaccinated population.", "content": "The differential tuberculin test in a BCG vaccinated population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203160"} {"pmid": "4203148", "title": "Use of videotape feedback as a psychotherapeutic nursing approach with long-term psychiatric patients: A pilot study.", "content": "Use of videotape feedback as a psychotherapeutic nursing approach with long-term psychiatric patients: A pilot study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203148"} {"pmid": "4203161", "title": "Cumulative effects of pulsed exposures of mycobacterium tuberculosis to isoniazid.", "content": "Cumulative effects of pulsed exposures of mycobacterium tuberculosis to isoniazid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203161"} {"pmid": "4203163", "title": "Bladder toxicity due to cyclophosphamide. Experimental induction and treatment.", "content": "Bladder toxicity due to cyclophosphamide. Experimental induction and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203163"} {"pmid": "4203162", "title": "Co-operative controlled trial of a standard regimen of streptomycin, PAS and isoniazid and three alternative regimens of chemotherapy in Britain. A report from the British Medical Research Council.", "content": "Co-operative controlled trial of a standard regimen of streptomycin, PAS and isoniazid and three alternative regimens of chemotherapy in Britain. A report from the British Medical Research Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203162"} {"pmid": "4203165", "title": "A possible D(CW) (e) gene complex of the Rh system.", "content": "A possible D(CW) (e) gene complex of the Rh system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203165"} {"pmid": "4203164", "title": "Rapid development of carcinoma in diverticulum of the bladder. A pitfall in conservative management.", "content": "Rapid development of carcinoma in diverticulum of the bladder. A pitfall in conservative management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203164"} {"pmid": "4203166", "title": "Blood group O(H)-like activity in extracts from some invertebrates. A study with catfish and eel sera and three anti-H lectins.", "content": "Blood group O(H)-like activity in extracts from some invertebrates. A study with catfish and eel sera and three anti-H lectins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203166"} {"pmid": "4203167", "title": "Small scale preparation and clinical use of factor IX-prothrombin complex.", "content": "Small scale preparation and clinical use of factor IX-prothrombin complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203167"} {"pmid": "4203168", "title": "Automated screening test for high titre tetanus antibody in donor plasma.", "content": "Automated screening test for high titre tetanus antibody in donor plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203168"} {"pmid": "4203169", "title": "The role of rheumatoid factor and related human antiglobulins in the radioimmunoassay (Ausria system) for the detection of hepatitis B antigen.", "content": "The role of rheumatoid factor and related human antiglobulins in the radioimmunoassay (Ausria system) for the detection of hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203169"} {"pmid": "4203173", "title": "Free zone electrophoresis of amniotic fluid in normal pregnancies and in pregnancies complicated by haemolytic disease.", "content": "Free zone electrophoresis of amniotic fluid in normal pregnancies and in pregnancies complicated by haemolytic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203173"} {"pmid": "4203174", "title": "Studies on reovirus-antigens. I. Preparation of reovirus-specific immune serum in the rabbit by means of active immunization through the scarified skin.", "content": "Studies on reovirus-antigens. I. Preparation of reovirus-specific immune serum in the rabbit by means of active immunization through the scarified skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203174"} {"pmid": "4203176", "title": "Kinetics of the attachment of radioisotope-labelled adenovirus hemagglutinins to red blood cells and their detachment by antibody and by nonlabelled hemagglutinins of homologous and heterologous types.", "content": "Kinetics of the attachment of radioisotope-labelled adenovirus hemagglutinins to red blood cells and their detachment by antibody and by nonlabelled hemagglutinins of homologous and heterologous types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203176"} {"pmid": "4203175", "title": "Studies on reovirus-antigens. II. Segregation of reovirus-antigens by chromatography on ecteola-cellulose and by centrifugation in a sucrose density gradient.", "content": "Studies on reovirus-antigens. II. Segregation of reovirus-antigens by chromatography on ecteola-cellulose and by centrifugation in a sucrose density gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203175"} {"pmid": "4203177", "title": "Effect of water on the bacterial flora of swimmers' ears.", "content": "Effect of water on the bacterial flora of swimmers' ears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203177"} {"pmid": "4203178", "title": "Trigeminal-facial nerve communications. Their function in facial muscle innervation and reinnervation.", "content": "Trigeminal-facial nerve communications. Their function in facial muscle innervation and reinnervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203178"} {"pmid": "4203179", "title": "Infantile sexuality in monkeys.", "content": "Infantile sexuality in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203179"} {"pmid": "4203180", "title": "Equations of substrate-limited growth: the case for blackman kinetics.", "content": "Equations of substrate-limited growth: the case for blackman kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203180"} {"pmid": "4203181", "title": "Detection of myeloma cells in the urine sediment.", "content": "Detection of myeloma cells in the urine sediment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203181"} {"pmid": "4203182", "title": "Polychlorinated biphenyls in the seastar Acanthaster planci.", "content": "Polychlorinated biphenyls in the seastar Acanthaster planci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203182"} {"pmid": "4203183", "title": "Demonstration of 2-oxoglutarate: glyoxylate carboligase activity in Tetrahymena pyriformis.", "content": "Demonstration of 2-oxoglutarate: glyoxylate carboligase activity in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203183"} {"pmid": "4203184", "title": "Inhibition of ribonuclease activity by bentonite.", "content": "Inhibition of ribonuclease activity by bentonite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203184"} {"pmid": "4203198", "title": "Prefrontal lobe functions and the neocortical commissures in monkeys.", "content": "Prefrontal lobe functions and the neocortical commissures in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203198"} {"pmid": "4203200", "title": "Mesencephalic control of lateral geniculate nucleus in primates. II. Effective loci.", "content": "Mesencephalic control of lateral geniculate nucleus in primates. II. Effective loci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203200"} {"pmid": "4203199", "title": "Mesencephalic control of lateral geniculate nucleus in primates. I. Electrophysiology.", "content": "Mesencephalic control of lateral geniculate nucleus in primates. I. Electrophysiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203199"} {"pmid": "4203201", "title": "Mesencephalic control of lateral geniculate nucleus in primates. 3. Modifications with state of alertness.", "content": "Mesencephalic control of lateral geniculate nucleus in primates. 3. Modifications with state of alertness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203201"} {"pmid": "4203202", "title": "A controlled trial of ambulant out-patient treatment and in-patient rest in bed in the management of tuberculosis of the spine in young Korean patients on standard chemotherapy a study in Masan, Korea. First report of the Medical Research Council Working Party on Tuberculosis of the Spine.", "content": "A controlled trial of ambulant out-patient treatment and in-patient rest in bed in the management of tuberculosis of the spine in young Korean patients on standard chemotherapy a study in Masan, Korea. First report of the Medical Research Council Working Party on Tuberculosis of the Spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203202"} {"pmid": "4203204", "title": "Non-flagellate Pseudomonas aeruginosa in pathological material.", "content": "Non-flagellate Pseudomonas aeruginosa in pathological material. Three isolates of non-flagellate Pseudomonas aeruginosa obtained from pathological material of human cases are described. Two were found in urinary tract infections and the third in a respiratory infection. They were shown by typing methods to be distinct strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203204"} {"pmid": "4203203", "title": "Anterior fusion of the spine for infective lesions in adults.", "content": "Anterior fusion of the spine for infective lesions in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203203"} {"pmid": "4203205", "title": "An automated method for the microbiological assay of serum pyridoxal.", "content": "An automated method for the microbiological assay of serum pyridoxal. A fully automated method for the measurement of serum pyridoxal has been developed. Acid phosphatase was used for dephosphorylation and precipitation of the serum proteins was not required. A chloramphenicol-resistant strain of L. casei was used as the test organism and this removed the need for sterilization. The method gives highly reproducible results, and is suitable for population and institutional studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203205"} {"pmid": "4203207", "title": "Inactivation of endotoxin by serum: a phylogenetic study.", "content": "Inactivation of endotoxin by serum: a phylogenetic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203207"} {"pmid": "4203208", "title": "Notes. Studies of amniotic fluid in women infected with rubella.", "content": "Notes. Studies of amniotic fluid in women infected with rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203208"} {"pmid": "4203209", "title": "Neuronal alterations in developing cortical infarction. An experimental study in monkeys.", "content": "Neuronal alterations in developing cortical infarction. An experimental study in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203209"} {"pmid": "4203210", "title": "Cerebral radiation necrosis simulating a brain tumor. Case report.", "content": "Cerebral radiation necrosis simulating a brain tumor. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203210"} {"pmid": "4203212", "title": "Vasodilating effect of crude platycodin in anesthetized dogs.", "content": "Vasodilating effect of crude platycodin in anesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203212"} {"pmid": "4203211", "title": "Adrenergic mechanism in Tetrahymena. II. Effect of adrenaline on cell proliferation.", "content": "Adrenergic mechanism in Tetrahymena. II. Effect of adrenaline on cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203211"} {"pmid": "4203213", "title": "Comparative studies of hepatic nicotine metabolizing enzyme activities in monkeys and dogs.", "content": "Comparative studies of hepatic nicotine metabolizing enzyme activities in monkeys and dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203213"} {"pmid": "4203214", "title": "Change in catecholamine content of Tetrahymena pyriformis W during growth.", "content": "Change in catecholamine content of Tetrahymena pyriformis W during growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203214"} {"pmid": "4203215", "title": "Comparison of two test kit methods for detection of occult blood in animal faeces.", "content": "Comparison of two test kit methods for detection of occult blood in animal faeces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203215"} {"pmid": "4203206", "title": "Influence of temperature on Drosophila alcohol dehydrogenase polymorphism.", "content": "Influence of temperature on Drosophila alcohol dehydrogenase polymorphism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203206"} {"pmid": "4203238", "title": "Homologous interference of lymphocytic choriomeningitis virus.", "content": "Homologous interference of lymphocytic choriomeningitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203238"} {"pmid": "4203239", "title": "Comparative analysis of interlaboratory variation in drug sensitivity test for Mycobacterium tuberculosis.", "content": "Comparative analysis of interlaboratory variation in drug sensitivity test for Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203239"} {"pmid": "4203240", "title": "Bacteriophage typing of Mycobacterium ranae (Fortuitum). The correlation of lysis by mycobacteriophage BK4 and inositol utilisation.", "content": "Bacteriophage typing of Mycobacterium ranae (Fortuitum). The correlation of lysis by mycobacteriophage BK4 and inositol utilisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203240"} {"pmid": "4203241", "title": "Haemolytic activity of various strains of Acinetobacter.", "content": "Haemolytic activity of various strains of Acinetobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203241"} {"pmid": "4203242", "title": "Production of cold agglutinins in rabbits induced by Mycoplasma pneumoniae, Listeria monocytogenes or Streptococcus MG.", "content": "Production of cold agglutinins in rabbits induced by Mycoplasma pneumoniae, Listeria monocytogenes or Streptococcus MG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203242"} {"pmid": "4203244", "title": "Morphological determinants in O2-transfer across the human and Rhesus hemochorial placenta.", "content": "Morphological determinants in O2-transfer across the human and Rhesus hemochorial placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203244"} {"pmid": "4203243", "title": "Placental function and oxygenation in the fetus.", "content": "Placental function and oxygenation in the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203243"} {"pmid": "4203245", "title": "Threshold values of oxygen deficiency leading to cardiovascular and brain pathological changes in term monkey fetuses.", "content": "Threshold values of oxygen deficiency leading to cardiovascular and brain pathological changes in term monkey fetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203245"} {"pmid": "4203246", "title": "Experimental models for in vivo and in vitro investigations on placental hemodynamics and oxygen supply to the fetus.", "content": "Experimental models for in vivo and in vitro investigations on placental hemodynamics and oxygen supply to the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203246"} {"pmid": "4203247", "title": "Existing anatomical parameters and the need for further determinations for various tissue structures.", "content": "Existing anatomical parameters and the need for further determinations for various tissue structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203247"} {"pmid": "4203248", "title": "Effect of carbonic anhydrase on the facilitated diffusion of CO2 through bicarbonate solutions.", "content": "Effect of carbonic anhydrase on the facilitated diffusion of CO2 through bicarbonate solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203248"} {"pmid": "4203258", "title": "Time course of weight increase of anterior pituitary and thyroxine binding to adenopituitary proteins after a single administration of estrogen.", "content": "Time course of weight increase of anterior pituitary and thyroxine binding to adenopituitary proteins after a single administration of estrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203258"} {"pmid": "4203259", "title": "The detection of LH activity in sheep urine by radioimmunoassay.", "content": "The detection of LH activity in sheep urine by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203259"} {"pmid": "4203249", "title": "Serial passage of 3 strains of avian infectious bronchitis virus in African green monkey kidney cells (VERO).", "content": "Serial passage of 3 strains of avian infectious bronchitis virus in African green monkey kidney cells (VERO).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203249"} {"pmid": "4203252", "title": "Role of desquamated epithelial cells in transmission of Marek's disease.", "content": "Role of desquamated epithelial cells in transmission of Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203252"} {"pmid": "4203251", "title": "Isolation of type-A influenza viruses from imported exotic birds.", "content": "Isolation of type-A influenza viruses from imported exotic birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203251"} {"pmid": "4203261", "title": "Notes on reproduction in captive squirrel monkeys (Saimiri sciureus).", "content": "Notes on reproduction in captive squirrel monkeys (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203261"} {"pmid": "4203262", "title": "Evaluation of the water incentive method of social dominance measurement in primates.", "content": "Evaluation of the water incentive method of social dominance measurement in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203262"} {"pmid": "4203250", "title": "Effect of virus pathogenicity on antibody production in Marek's disease.", "content": "Effect of virus pathogenicity on antibody production in Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203250"} {"pmid": "4203264", "title": "Applicability of heat-stable deoxyribonuclease assay for assessment of staphylococcal growth and the likely presence of enterotoxin in cheese.", "content": "Applicability of heat-stable deoxyribonuclease assay for assessment of staphylococcal growth and the likely presence of enterotoxin in cheese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203264"} {"pmid": "4203263", "title": "Blood groups, red cell enzymes and serum proteins of baboons and vervets.", "content": "Blood groups, red cell enzymes and serum proteins of baboons and vervets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203263"} {"pmid": "4203265", "title": "Effect of pesticides on the methylene blue reduction test in milk.", "content": "Effect of pesticides on the methylene blue reduction test in milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203265"} {"pmid": "4203253", "title": "An easy method for making cutters to use in the agar-gel diffusion technique.", "content": "An easy method for making cutters to use in the agar-gel diffusion technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203253"} {"pmid": "4203269", "title": "Are all those lab tests really worth it?", "content": "Are all those lab tests really worth it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203269"} {"pmid": "4203273", "title": "Summary of recent studies in Japan on methyl mercury poisoning.", "content": "Summary of recent studies in Japan on methyl mercury poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203273"} {"pmid": "4203275", "title": "Studies on the mechanism of learning. II. On the ionic nature of the dendritic action potentials and mescaline spikes.", "content": "Studies on the mechanism of learning. II. On the ionic nature of the dendritic action potentials and mescaline spikes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203275"} {"pmid": "4203277", "title": "Observations on the effect of changes in arterial oxygenation on adenosine induced coronary vasodilation.", "content": "Observations on the effect of changes in arterial oxygenation on adenosine induced coronary vasodilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203277"} {"pmid": "4203279", "title": "The effect of glyceryl trinitate on coronary collateral flow--a preliminary report.", "content": "The effect of glyceryl trinitate on coronary collateral flow--a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203279"} {"pmid": "4203278", "title": "Local oxygen tension and blood flow in the normal and chronic ischemic myocardium in the anesthetized dog.", "content": "Local oxygen tension and blood flow in the normal and chronic ischemic myocardium in the anesthetized dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203278"} {"pmid": "4203280", "title": "Coronary artery reperfusion: early effects on coronary hemodynamics.", "content": "Coronary artery reperfusion: early effects on coronary hemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203280"} {"pmid": "4203283", "title": "Effect of incubation time on folate values.", "content": "Effect of incubation time on folate values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203283"} {"pmid": "4203284", "title": "Simple pyrazinamidase and urease tests for routine identification of mycobacteria.", "content": "Simple pyrazinamidase and urease tests for routine identification of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203284"} {"pmid": "4203285", "title": "Clarification of sonic lysates of Mycobacterium tuberculosis.", "content": "Clarification of sonic lysates of Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203285"} {"pmid": "4203286", "title": "Isolation of tuberculin skin test reactive proteins from heated culture filtrate of Mycobacterium tuberculosis H37Rv.", "content": "Isolation of tuberculin skin test reactive proteins from heated culture filtrate of Mycobacterium tuberculosis H37Rv.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203286"} {"pmid": "4203287", "title": "Modern concepts in the management of surgical diabetic patients.", "content": "Modern concepts in the management of surgical diabetic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203287"} {"pmid": "4203288", "title": "Polycystic jaws in patients with cleft lip and palate.", "content": "Polycystic jaws in patients with cleft lip and palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203288"} {"pmid": "4203289", "title": "Comparative observations on intertubular lymphatics and the organization of the interstitial tissue of the mammalian testis.", "content": "Comparative observations on intertubular lymphatics and the organization of the interstitial tissue of the mammalian testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203289"} {"pmid": "4203290", "title": "Periodic thermal stress: optimal spacing predicted by a simple set-back model of cell division synchronization.", "content": "Periodic thermal stress: optimal spacing predicted by a simple set-back model of cell division synchronization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203290"} {"pmid": "4203291", "title": "Failure of TSH radioimmunoassay to consistently detect mild TSH mediated thyroid stimulation.", "content": "Failure of TSH radioimmunoassay to consistently detect mild TSH mediated thyroid stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203291"} {"pmid": "4203292", "title": "Serum triiodothyronine in health and disease.", "content": "Serum triiodothyronine in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203292"} {"pmid": "4203293", "title": "Serum TSH responses to intravenously and orally administered TRH in man after thyroidectomy for carcinoma of the thyroid.", "content": "Serum TSH responses to intravenously and orally administered TRH in man after thyroidectomy for carcinoma of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203293"} {"pmid": "4203296", "title": "Mendelian segregation of a mouse antibody idiotype.", "content": "Mendelian segregation of a mouse antibody idiotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203296"} {"pmid": "4203295", "title": "Bursal and postbursal stem cells in chicken. Functional characteristics.", "content": "Bursal and postbursal stem cells in chicken. Functional characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203295"} {"pmid": "4203294", "title": "Mesenteric lymph as a major source of serum IgA in guinea pigs and rats.", "content": "Mesenteric lymph as a major source of serum IgA in guinea pigs and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203294"} {"pmid": "4203304", "title": "Growth hormone levels in vitamin B6-deficient rats.", "content": "Growth hormone levels in vitamin B6-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203304"} {"pmid": "4203305", "title": "Plasma disappearance of radioiodinated dog growth hormone in the dog.", "content": "Plasma disappearance of radioiodinated dog growth hormone in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203305"} {"pmid": "4203306", "title": "Importance of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis.", "content": "Importance of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203306"} {"pmid": "4203307", "title": "Studies on the conjugation of horseradish peroxidase to Fab fragments.", "content": "Studies on the conjugation of horseradish peroxidase to Fab fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203307"} {"pmid": "4203308", "title": "Micro-hemagglutination tests for detection of native and single-strand DNA antibodies and circulating DNA antigen.", "content": "Micro-hemagglutination tests for detection of native and single-strand DNA antibodies and circulating DNA antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203308"} {"pmid": "4203310", "title": "Proceedings: The mechanism of action of prostaglandin F2a on cerebral flow in the baboon.", "content": "Proceedings: The mechanism of action of prostaglandin F2a on cerebral flow in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203310"} {"pmid": "4203309", "title": "Differential effects of glycerol treatment on membrane capacity and excitation-contraction coupling in toad sartorius fibres.", "content": "Differential effects of glycerol treatment on membrane capacity and excitation-contraction coupling in toad sartorius fibres. Changes in membrane capacity and excitation-contraction coupling caused by glycerol movements have been investigated in toad sartorius fibres using a standard glycerol-Ringer solution containing 400 mM glycerol.1. The rates of glycerol movement, in and out of fibres, were determined by measuring diameter changes in single fibres. Glycerol equilibrated across the surface membrane within 20-25 min after changes in extracellular glycerol concentration.2. The reduction in membrane capacity, which occurs when glycerol-loaded fibres are returned to Ringer solution, was slower than, and not dependent on, changes in fibre volume.3. To obtain the maximum reduction in membrane capacity, it was necessary to expose fibres to glycerol-Ringer for 50-60 min and then to return them to Ringer for at least 60 min. If preparations were not kept in Ringer for the full 50-60 min, the reduction in membrane capacity could be partially or completely reversed by returning the fibres to glycerol-Ringer.4. When fibres were exposed to glycerol-Ringer there was an initial transient contracture: twitches and K contractures were rapidly inhibited, and then slowly recovered over the next 40-50 min. In some preparations, eventual potentiation of twitches was seen.5. When returned to Ringer solution after 60 min in glycerol-Ringer, preparations lost twitches and K contractures within 5-10 min. The time course of this effect was very similar to the time course of the recovery of the normal volume after the initial swelling.6. The briefer the exposure to the glycerol-Ringer, the slower the loss of twitches and K contractures on return to Ringer. In contrast to the loss of membrane capacity, the lesion of excitation-contraction coupling was essentially irreversible. Exposure times as brief as 5 min were eventually effective in producing paralysed fibres which, however, still responded to caffeine.7. The differences in the glycerol load-times required to produce decoupling of excitation and contraction, and disconnexion of the transverse tubules, show that the two effects are separable and that the first does not depend on the second.8. It is proposed that the two lesions obtained in glycerol-treated fibres may be related to distension of the transverse tubular system. It is shown in an Appendix that the outward movement of glycerol from sarcoplasm to transverse tubules would be expected to produce some early swelling of the tubules and this is related to the loss of contraction. Furthermore, much greater swelling would occur if a slow-loading compartment (presumed to be the sarcoplasmic reticulum) dumped glycerol into the transverse tubules: it is thought that this is related to the disconnexion of the transverse tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203309"} {"pmid": "4203311", "title": "Proceedings: Reactive hyperaemia in the dog heart: assessment of post-hyperaemic coronary vascular reactivity and of the effects of temporarily restricting arterial inflow.", "content": "Proceedings: Reactive hyperaemia in the dog heart: assessment of post-hyperaemic coronary vascular reactivity and of the effects of temporarily restricting arterial inflow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203311"} {"pmid": "4203312", "title": "Proceedings: Extrinsic and intrinsic hysteresis of intrapulmonary bronchi in situ.", "content": "Proceedings: Extrinsic and intrinsic hysteresis of intrapulmonary bronchi in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203312"} {"pmid": "4203313", "title": "Dexamethasone in the management of kerosene pneumonia.", "content": "Dexamethasone in the management of kerosene pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203313"} {"pmid": "4203316", "title": "A method of fixing rat testis for light and electron microscopy.", "content": "A method of fixing rat testis for light and electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203316"} {"pmid": "4203315", "title": "Growing and embedding fern gametophytes for autoradiographic studies.", "content": "Growing and embedding fern gametophytes for autoradiographic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203315"} {"pmid": "4203320", "title": "Regulation of transport systems: a means of controlling metabolic rates.", "content": "Regulation of transport systems: a means of controlling metabolic rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203320"} {"pmid": "4203321", "title": "Control of photosynthetic carbon metabolism.", "content": "Control of photosynthetic carbon metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203321"} {"pmid": "4203322", "title": "Bladder neck obstruction in young male patients.", "content": "Bladder neck obstruction in young male patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203322"} {"pmid": "4203323", "title": "Cecovesicovaginal fistula.", "content": "Cecovesicovaginal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203323"} {"pmid": "4203331", "title": "Effect of pH, sodium chloride, and sodium nitrite on enterotoxin A production.", "content": "Effect of pH, sodium chloride, and sodium nitrite on enterotoxin A production. The combined effects of pH, sodium chloride, and sodium nitrite were studied by using a dialysis sac technique in brain heart infusion broth. Growth and enterotoxin A production by Staphylococcus aureus strain 100 were found to decrease with the addition of sodium nitrite, with a decrease in pH from 7.0, and with an increase in sodium chloride concentration. The significance of these results is discussed in relation to cured meats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203331"} {"pmid": "4203332", "title": "Field evaluation of the gel diffusion test for the diagnosis of ram epididymitis caused by Brucella ovis.", "content": "Field evaluation of the gel diffusion test for the diagnosis of ram epididymitis caused by Brucella ovis. A comparison was made with the microslide gel diffusion technique, the complement fixation test, cultural isolation, and clinical examination in detecting ram epididymitis caused by Brucella ovis. The results of the gel diffusion method are shown to be similar to those obtained by the complement fixation test and isolation of B. ovis from cultures of semen. The technique offers a reliable diagnostic method adaptable to field use in controlling ovine brucellosis and is more practical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203332"} {"pmid": "4203333", "title": "Multiplication of nosocomial pathogens in intravenous feeding solutions.", "content": "Multiplication of nosocomial pathogens in intravenous feeding solutions. A major problem in total parenteral nutrition is sepsis, particularly that caused by Candida. Studies of four solutions, a casein hydrolysate, a fibrin hydrolysate, and two crystalline amino acid solutions, show that the protein hydrolysate solutions appear to be highly selective for Candida over bacteria, whereas the crystalline amino acid solutions are not. These findings suggest that the crystalline amino acid preparations may offer a partial solution to the infection problem by minimizing the contribution of the solution as a reservoir for organism multiplication, because they retard the growth of both bacteria and Candida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203333"} {"pmid": "4203335", "title": "Assimilation of hydrocarbons by Pseudomonas strains isolated from human clinical specimens.", "content": "Assimilation of hydrocarbons by Pseudomonas strains isolated from human clinical specimens. Twenty strains of Pseudomonas isolated from human clinical specimens on routine laboratory media, without hydrocarbon enrichment and unselected for their growth on hydrocarbons, were tested for their ability to utilize a series of eight n-alkanes and two 1-alkenes as a sole carbon and energy source for growth. Hydrocarbon assimilation does occur with such isolates relative to the chain length and the degree of saturation of the hydrocarbon. The data presented show that all 16 stains of Pseudomonas aeruginosa studied grew readily on dodecane through hexadecane and on 1-hexadecene. In addition, most strains of this species grew on undecane and 1-dodecene after prolonged incubation. There was a long lag period, usually a minimum of 4 days, before onset of growth on any hydrocarbon. In no case did hexane or decane support growth. Two strains each of P. maltophilia and P. stutzeri were unable to grow on any of the hydrocarbons tested. Hexane in concentrations above 1% (vol/vol) is bactericidal toward the Pseudomonas inoculum. It is toxic even to cells utilizing different hydrocarbon for growth. The addition of 1% hexane to 1% (vol/vol) hexadecane markedly prolonged the lag phase of P. aeruginosa utilizing the hexadecane for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203335"} {"pmid": "4203334", "title": "Comparison of three culture media for isolation of Mycobacterium tuberculosis: a 6-year study.", "content": "Comparison of three culture media for isolation of Mycobacterium tuberculosis: a 6-year study. Among 2,648 specimens positive on culture for Mycobacterium tuberculosis over a 6-year period, 82% grew on Lowenstein-Jensen medium (LJ), 79% on American Trudeau Society (ATS), and 56% on Middlebrook 7H10 (7H10). When these commercial culture media were compared in regard to the number of acid-fast bacilli seen on the original smears, LJ cultures were found to have the highest isolation rates for each smear category, and 7H10 had the lowest rates. Comparing the media from the aspect of number of mycobacterial colonies produced, LJ and ATS had the highest average colony counts, followed by 7H10. These findings were relatively constant over the 6-year period. One possible reason for the low positive rate of 7H10 was the lack of CO(2) enrichment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203334"} {"pmid": "4203336", "title": "Scanning electron microscopy of bacterial colonies.", "content": "Scanning electron microscopy of bacterial colonies. A technique is described for observing bacterial colony growth. Bacillus cereus, B. subtilis, and B. cereus var. mycoides were grown on strips of dialysis membrane layered on nutrient agar. Microcolonies of the organisms on strips were fixed in Formalin vapor in situ; the strips then were removed from the agar and secured to scanning microscope specimen stubs without markedly disturbing the cellular arrangement. Scanning electron micrographs clearly depict morphology of individual cells, as well as the spatial orientation of cells within the colony. This technique is reproducible, adaptable, and simple.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203336"} {"pmid": "4203337", "title": "Carbohydrate metabolism in lactic streptococci: fate of galactose supplied in free or disaccharide form.", "content": "Carbohydrate metabolism in lactic streptococci: fate of galactose supplied in free or disaccharide form. Phosphorylation of free galactose by lactic streptococci was mediated by an adenosine triphosphate (ATP)-dependent kinase. The phosphoenolpyruvate (PEP) phosphotransferase system (PTS) was involved to a limited extent in transport of the sugar. The conversion of free galactose to glucose also was demonstrated, and uridine diphosphogalactose-4-epimerase was demonstrated to account for this change. Galactose, supplied as lactose, was phosphorylated during transport by means of the PTS with PEP as the phosphate donor. Data also indicated that galactose derived from lactose was catabolized by the glycolytic pathway. Results showed the participation of ATP or PEP, or both, in the phosphorylation of five growth sugars for lactic streptococci, namely, galactose, glucose, lactose, maltose, and mannose. Free galactose was phosphorylated exclusively by ATP except when cells were grown on galactose; in this case, slight involvement of PEP in phosphorylation also was noted. Lactose phosphorylation was much more effective with PEP except when cells were grown on lactose, in which case ATP was equally effective. Glucose was phosphorylated to about the same degree by either ATP or PEP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203337"} {"pmid": "4203338", "title": "Population changes in enteric bacteria and other microorganisms during aerobic thermophilic windrow composting.", "content": "Population changes in enteric bacteria and other microorganisms during aerobic thermophilic windrow composting. Composting of wastes from swine feeding operations was studied. The effects of the frequency of turning the wastes and addition of straw to improve the physical structure were studied to determine the most effective technique to rapidly increase the temperature and, consequently, destroy coliforms and Salmonella. Four different treatments were studied; the results showed that, with addition of 5% (wt/wt) straw and mechanical turning of the compost 20 times per week, the temperature reached 60 C within 3 days and enteric bacteria were destroyed within 14 days.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203338"} {"pmid": "4203339", "title": "Localized epidermolysis bullosa. Report of two cases and evaluation of therapy with glutaraldehyde.", "content": "Localized epidermolysis bullosa. Report of two cases and evaluation of therapy with glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203339"} {"pmid": "4203340", "title": "Letter: Photosensitive lichenoid eruption associated with demeclocycline.", "content": "Letter: Photosensitive lichenoid eruption associated with demeclocycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203340"} {"pmid": "4203341", "title": "Azotobacter vineland II RNA polymerase. XI. Effect of transcription on rifampicin binding.", "content": "Azotobacter vineland II RNA polymerase. XI. Effect of transcription on rifampicin binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203341"} {"pmid": "4203342", "title": "Isolation of a replication-complex from eukaryotes.", "content": "Isolation of a replication-complex from eukaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203342"} {"pmid": "4203343", "title": "Antigenic homology of eukaryotic RNA polymerases.", "content": "Antigenic homology of eukaryotic RNA polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203343"} {"pmid": "4203344", "title": "A new polypeptide associated with RNA polymerase from Bacillus subtilis during late stages of vegetative growth.", "content": "A new polypeptide associated with RNA polymerase from Bacillus subtilis during late stages of vegetative growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203344"} {"pmid": "4203345", "title": "Effect of age of the rat on induction of acetylcholinesterase of the brain by 17 beta-estradiol.", "content": "Effect of age of the rat on induction of acetylcholinesterase of the brain by 17 beta-estradiol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203345"} {"pmid": "4203346", "title": "Proceedings: Prostaglandin generation maintains the smooth muscle tone of the rabbit isolated jejunum.", "content": "Proceedings: Prostaglandin generation maintains the smooth muscle tone of the rabbit isolated jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203346"} {"pmid": "4203347", "title": "Proceedings: Effect of oxypertine on anxiety-induced behaviour in baboons.", "content": "Proceedings: Effect of oxypertine on anxiety-induced behaviour in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203347"} {"pmid": "4203348", "title": "A comparative study of the accessory ganglia of Axenfeld.", "content": "A comparative study of the accessory ganglia of Axenfeld.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203348"} {"pmid": "4203349", "title": "Effects of feeding and fasting on the insulin secretory response to glucose and sulfonylureas in intact rats and isolated perfused rat pancreas.", "content": "Effects of feeding and fasting on the insulin secretory response to glucose and sulfonylureas in intact rats and isolated perfused rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203349"} {"pmid": "4203354", "title": "Sex-linked blood-glucose pattern in rats under varying test conditions.", "content": "Sex-linked blood-glucose pattern in rats under varying test conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203354"} {"pmid": "4203355", "title": "Immunoglobulin classes in mammalian species identifed by cross-reactivity with antisera to human immunoglobulin.", "content": "Immunoglobulin classes in mammalian species identifed by cross-reactivity with antisera to human immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203355"} {"pmid": "4203356", "title": "Characterisation of an allergen extracted from Ascaris suum. Determination of the molecular weight, isoelectric point, amino acid and carbohydrate content of the native allergen.", "content": "Characterisation of an allergen extracted from Ascaris suum. Determination of the molecular weight, isoelectric point, amino acid and carbohydrate content of the native allergen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203356"} {"pmid": "4203358", "title": "The structure of the zonula occludens. A single fibril model based on freeze-fracture.", "content": "The structure of the zonula occludens. A single fibril model based on freeze-fracture. Replicas of freeze-fractured toad urinary bladder and gallbladder were analysed in an attempt to determine the fracturing properties and structure of the zonula occludens (tight junction). Chalcroft and Bullivant have proposed that the junction has a double set of fibrils with one set associated with each of the adjacent cell membranes. However, the fracturing pattern that is observed might also result from only a single set of fibrils which is shared by the adjacent membranes if fracturing occurred around either side of the fibrils. These two models predict quite different structures at regions of the junction where tranl sitions are made between face A and face B. The relative heights of face A and face B and the shape of the transition from face A to face B do not agree with that expected according to the two fibril model but agree exactly with that expected if only a single set of fibrils existed. Further evidence for the single fibril model is derived from fractures of the mucosa membrane which cross the junction to the membrane of the adjacent cell without deflection. Such fractures reveal a single ridge which appears to be identical to the juxtaluminal fibril of the junction. In addition, small ridges are occasionally found in place of the grooves on face B which, although not consistent with the double fibril model, is expected if the single fibril model were correct. Although alternative explanations might account for these observations, we believe that the simplest and most consistent explanation is that the zonula occludens fractures as would be expected of a single set of fibrils shared by adjacent cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203358"} {"pmid": "4203360", "title": "The effect of glutaraldehyde on catalase. Biochemical and cytochemical studies with beef liver catalase and rat liver peroxisomes.", "content": "The effect of glutaraldehyde on catalase. Biochemical and cytochemical studies with beef liver catalase and rat liver peroxisomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203360"} {"pmid": "4203359", "title": "Cryoprotectant-induced redistribution of intramembranous particles in mouse lymphocytes.", "content": "Cryoprotectant-induced redistribution of intramembranous particles in mouse lymphocytes. This study demonstrates, by freeze fracture, clustering of intramembranous particles caused by cryoprotectant treatment of intact unfixed mouse lymphoid cells. Both T and B cells react in a similar fashion, while similar clustering of particles is not observed in some other cell types. The intramembranous particles can be aggregated by incubating unfixed cells in glycerol or dimethylsulfoxide (DMSO) before freezing. The aggregation phenomenon is dependent on the length of time of exposure and the concentration of the cryoprotectants. Further, the cells remain viable and the cryoprotectant-induced clustering is completely reversible. Prefixation of glycerol-treated cells with glutaraldehyde prevents the formation of these particle clusters, and unfixed nonglycerinated cells show no clusters. Thin sections of cells exposed to glycerol or DMSO without previous fixation exhibit bizarre membrane alterations and numerous other degenerative changes. These observations stress the importance of prefixation of lymphoid cells before exposure to glycerol or DMSO, as well as indicate that the membrane characteristics of certain cell types may be probed by glycerol treatment of unfixed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203359"} {"pmid": "4203362", "title": "Studies on the virulence of Neisseria gonorrhoeae. II. Relation of susceptibility to antibiotics and resistance to phagocytosis by polymorphonuclear leukocytes.", "content": "Studies on the virulence of Neisseria gonorrhoeae. II. Relation of susceptibility to antibiotics and resistance to phagocytosis by polymorphonuclear leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203362"} {"pmid": "4203364", "title": "Synthesis and biological activities of substituted glycyrrhetic acids.", "content": "Synthesis and biological activities of substituted glycyrrhetic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203364"} {"pmid": "4203361", "title": "Nucleolar and perichromosomal RNA synthesis during meiotic prophase in the mouse testis.", "content": "Nucleolar and perichromosomal RNA synthesis during meiotic prophase in the mouse testis. The transcriptional activity during meiotic prophase in the mouse testis is studied with light microscopy and high-resolution autoradiographic techniques using [(3)H]uridine as a labeled precursor. In the present study, two types of RNA synthesis are detected during meiotic prophase: an extranucleolar RNA synthesis of perichromosomal localization and a nucleolar RNA synthetic activity. In some of the autosomes and close to the basal knobs, the activity of the nucleolar organizers is evidenced by the incorporation of [(3)H]uridine into nucleolar masses from zygotene on and at earlier labeling times. The evolution of nucleoli and the formation of a nucleolus attached to the sex pair are described during the different meiotic stages. Perichromosomal labeling, from leptotene on, reaches a maximum during middle pachytene and falls progressively to a low level at longer incorporation times. Sertoli's cell, the most active RNA synthetic cell in the seminiferous epithelium, rises to a maximum of labeling and drops at earlier times compared with the meiotic prophase cells. The condensed sex chromosomes show some scattered silver grains especially at middle pachytene. The axial chromosome cores and synaptonemal complexes are devoid of silver grains during the meiotic prophase. The observations suggest that a control mechanism operates during meiotic prophase to regulate transcriptional activity in the sex chromosomes and to provide differential RNA synthesis in autosomal bivalents at various stages of prophase and within certain segments of the chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203361"} {"pmid": "4203363", "title": "Current techniques in assessment of protein nutritional status in the community.", "content": "Current techniques in assessment of protein nutritional status in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203363"} {"pmid": "4203366", "title": "Antiparasitic 5-nitrothiazoles and 5-nitro-4-thiazolines. 4.", "content": "Antiparasitic 5-nitrothiazoles and 5-nitro-4-thiazolines. 4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203366"} {"pmid": "4203365", "title": "Synthesis of 2-oxygenated glycyrrhetic acid derivatives.", "content": "Synthesis of 2-oxygenated glycyrrhetic acid derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203365"} {"pmid": "4203367", "title": "Folic acid analogs. Modifications in the benzene-ring region. 4. 3'-Ethyl- and 3'-isopropylfolic acids.", "content": "Folic acid analogs. Modifications in the benzene-ring region. 4. 3'-Ethyl- and 3'-isopropylfolic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203367"} {"pmid": "4203369", "title": "Syntheses and biological activities of 7-ethyl-8-bromo-10-(1'-D-ribityl)isoalloxazine and 7-bromo-8-ethyl-10-(1'-D-ribityl)isoalloxazine, analogs of riboflavin.", "content": "Syntheses and biological activities of 7-ethyl-8-bromo-10-(1'-D-ribityl)isoalloxazine and 7-bromo-8-ethyl-10-(1'-D-ribityl)isoalloxazine, analogs of riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203369"} {"pmid": "4203368", "title": "Synthesis and biological evaluation of isofolic acid.", "content": "Synthesis and biological evaluation of isofolic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203368"} {"pmid": "4203357", "title": "Experience with Björk-Shiley valvular replacement. A preliminary report.", "content": "Experience with Björk-Shiley valvular replacement. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203357"} {"pmid": "4203370", "title": "Ribosomal RNA cistrons in Euglena gracilis.", "content": "Ribosomal RNA cistrons in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203370"} {"pmid": "4203371", "title": "Prostaglandin inhibition of metabolically induced coronary vasodilation.", "content": "Prostaglandin inhibition of metabolically induced coronary vasodilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203371"} {"pmid": "4203372", "title": "Inotropic stimuli and systolic transmembrane calcium flow in depolarized guinea-pig atria.", "content": "Inotropic stimuli and systolic transmembrane calcium flow in depolarized guinea-pig atria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203372"} {"pmid": "4203373", "title": "Metabolism of diazoxide in man and experimental animals.", "content": "Metabolism of diazoxide in man and experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203373"} {"pmid": "4203374", "title": "Pharmacodynamic interactions among gluco-, mineralo- and glucomineralocorticoids, pregnenolone-16alpha-carbonitrile and various drugs.", "content": "Pharmacodynamic interactions among gluco-, mineralo- and glucomineralocorticoids, pregnenolone-16alpha-carbonitrile and various drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203374"} {"pmid": "4203376", "title": "Plasma and erythrocyte zinc levels in protein-calorie malnutrition.", "content": "Plasma and erythrocyte zinc levels in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203376"} {"pmid": "4203377", "title": "Endotoxemia in the Rhesus monkey: alterations in host lipid and carbohydrate metabolism.", "content": "Endotoxemia in the Rhesus monkey: alterations in host lipid and carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203377"} {"pmid": "4203381", "title": "The absorption, metabolism and excretion of disodium cromoglycate in nine animal species.", "content": "The absorption, metabolism and excretion of disodium cromoglycate in nine animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203381"} {"pmid": "4203382", "title": "The relationship between inhibition of delta-aminolevulinic acid dehydratase by lead and lead mobilization by ethylenediamine tetraacetate (EDTA).", "content": "The relationship between inhibition of delta-aminolevulinic acid dehydratase by lead and lead mobilization by ethylenediamine tetraacetate (EDTA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203382"} {"pmid": "4203384", "title": "Intraepithelial parasitism as an infection mechanism in human paracoccidioidomycosis (South American blastomycosis).", "content": "Intraepithelial parasitism as an infection mechanism in human paracoccidioidomycosis (South American blastomycosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203384"} {"pmid": "4203387", "title": "Human intracranial atherosclerosis. An ultrastructural study of atheromatous plaques.", "content": "Human intracranial atherosclerosis. An ultrastructural study of atheromatous plaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203387"} {"pmid": "4203389", "title": "Serum immunoglobulin levels in atomic bomb survivors in Hiroshima, Japan.", "content": "Serum immunoglobulin levels in atomic bomb survivors in Hiroshima, Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203389"} {"pmid": "4203390", "title": "Observations on asymptomatic infections with Neisseria meningitidis.", "content": "Observations on asymptomatic infections with Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203390"} {"pmid": "4203394", "title": "Aldolase of lactic acid bacteria: a case history in the use of an enzyme as an evolutionary marker.", "content": "Aldolase of lactic acid bacteria: a case history in the use of an enzyme as an evolutionary marker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203394"} {"pmid": "4203398", "title": "Computer morphometrics in craniofacial biology.", "content": "Computer morphometrics in craniofacial biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203398"} {"pmid": "4203400", "title": "Increase in the longevity of adult Drosophila melanogaster kept in permanent darkness.", "content": "Increase in the longevity of adult Drosophila melanogaster kept in permanent darkness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203400"} {"pmid": "4203401", "title": "The thyroid and age.", "content": "The thyroid and age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203401"} {"pmid": "4203403", "title": "Editorial: Renal failure in tropical diseases.", "content": "Editorial: Renal failure in tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203403"} {"pmid": "4203404", "title": "Regeneration of the attachment apparatus on pulpless teeth denuded of cementum in the rhesus monkey.", "content": "Regeneration of the attachment apparatus on pulpless teeth denuded of cementum in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203404"} {"pmid": "4203393", "title": "Reduction of nitrogenous oxides by microorganisms.", "content": "Reduction of nitrogenous oxides by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203393"} {"pmid": "4203407", "title": "Potatoes and birth defects: summary.", "content": "Potatoes and birth defects: summary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203407"} {"pmid": "4203408", "title": "Investigations into the teratogenic potential of imperfect potatoes.", "content": "Investigations into the teratogenic potential of imperfect potatoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203408"} {"pmid": "4203409", "title": "Are potatoes teratogenic for experimental animals?", "content": "Are potatoes teratogenic for experimental animals?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203409"} {"pmid": "4203415", "title": "The origin of immunoglobulin-G in bovine tears.", "content": "The origin of immunoglobulin-G in bovine tears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203415"} {"pmid": "4203416", "title": "Analysis of C1 subcomponents in cell culture media of HeLa cells and diploid human fetal lung fibroblasts.", "content": "Analysis of C1 subcomponents in cell culture media of HeLa cells and diploid human fetal lung fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203416"} {"pmid": "4203418", "title": "Scanning the radiation field of a 25-MeV medical betatron using a new uniformity check system.", "content": "Scanning the radiation field of a 25-MeV medical betatron using a new uniformity check system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203418"} {"pmid": "4203396", "title": "Structure and synthesis of the ribosomal ribonucleic acid of prokaryotes.", "content": "Structure and synthesis of the ribosomal ribonucleic acid of prokaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203396"} {"pmid": "4203395", "title": "Moraxella, Acinetobacter, and the Mimeae.", "content": "Moraxella, Acinetobacter, and the Mimeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203395"} {"pmid": "4203421", "title": "Influence of certain pesticides on microorganisms. Influence of DDT on the synthesis of the particular amino acids in Chlorella vulgaris and Anabaena cylindrica.", "content": "Influence of certain pesticides on microorganisms. Influence of DDT on the synthesis of the particular amino acids in Chlorella vulgaris and Anabaena cylindrica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203421"} {"pmid": "4203419", "title": "Quantitative and qualitative aspects of the plasma protein binding of carbenoxolone, an ulcer-healing drug.", "content": "Quantitative and qualitative aspects of the plasma protein binding of carbenoxolone, an ulcer-healing drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203419"} {"pmid": "4203422", "title": "Plasma proteins in the semen of bulls.", "content": "Plasma proteins in the semen of bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203422"} {"pmid": "4203420", "title": "Interaction of drugs with thyroid hormone binding sites.", "content": "Interaction of drugs with thyroid hormone binding sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203420"} {"pmid": "4203423", "title": "Blood group homologues in orangutans and gorillas of the human Rh-Hr and the chimpanzee C-E-F systems.", "content": "Blood group homologues in orangutans and gorillas of the human Rh-Hr and the chimpanzee C-E-F systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203423"} {"pmid": "4203424", "title": "Feeding levels and feeding sites of red colobus (Colobus badius tephrosceles) in the Gombe National Park.", "content": "Feeding levels and feeding sites of red colobus (Colobus badius tephrosceles) in the Gombe National Park.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203424"} {"pmid": "4203425", "title": "The distribution of the white-collared mangabey, Cercocebus torquatus, in Nigeria.", "content": "The distribution of the white-collared mangabey, Cercocebus torquatus, in Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203425"} {"pmid": "4203426", "title": "Changes in the sexual behaviour of male rhesus monkeys (M. mulatta) at puberty. Comparisons with the behaviour of adults.", "content": "Changes in the sexual behaviour of male rhesus monkeys (M. mulatta) at puberty. Comparisons with the behaviour of adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203426"} {"pmid": "4203430", "title": "Advances in rehabilitative care lag behind progress in managing episodic disease.", "content": "Advances in rehabilitative care lag behind progress in managing episodic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203430"} {"pmid": "4203428", "title": "In vitro fertilization of human ova and blastocyst transfer. An invitational symposium.", "content": "In vitro fertilization of human ova and blastocyst transfer. An invitational symposium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203428"} {"pmid": "4203431", "title": "Pyrolysis-gas-liquid chromatography of fungi: numerical characterization of species variation among members of the Aspergillus glaucus group.", "content": "Pyrolysis-gas-liquid chromatography of fungi: numerical characterization of species variation among members of the Aspergillus glaucus group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203431"} {"pmid": "4203434", "title": "Nurse autonomy and accountability in organized nursing services.", "content": "Nurse autonomy and accountability in organized nursing services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203434"} {"pmid": "4203437", "title": "Concomitant occurrence of neurofibromatosis and carcinoid of the intestine.", "content": "Concomitant occurrence of neurofibromatosis and carcinoid of the intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203437"} {"pmid": "4203444", "title": "The histocompatibility complex of rhesus monkeys. I. Serology and genetics of the RhL-A system.", "content": "The histocompatibility complex of rhesus monkeys. I. Serology and genetics of the RhL-A system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203444"} {"pmid": "4203445", "title": "Scanning electron microscope observations on the spore of Nosema apis Zander.", "content": "Scanning electron microscope observations on the spore of Nosema apis Zander.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203445"} {"pmid": "4203446", "title": "Carcinoma of the ovary. Radiation therapy experience.", "content": "Carcinoma of the ovary. Radiation therapy experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203446"} {"pmid": "4203447", "title": "Mammary nodular hyperplasia in intact rhesus monkeys.", "content": "Mammary nodular hyperplasia in intact rhesus monkeys. Clinical and pathological findings of subcutaneous nodules in the breast regions of 2 untreated control intact female Rhesus monkeys in a long-term study of an oral contraceptive steroid are described. 1 nodule, which was excised early in the study, showed changes characteristic of nodular mammary hyperplasia; no features of neoplasia were present. Some of the nodules were transient. None of the nodules showed a progressive growth pattern during repeated clinical examination over 17-20 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203447"} {"pmid": "4203448", "title": "Besnoitia bennetti in two Mexican burros.", "content": "Besnoitia bennetti in two Mexican burros.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203448"} {"pmid": "4203450", "title": "Prognosis of depressed skull fracture.", "content": "Prognosis of depressed skull fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203450"} {"pmid": "4203451", "title": "Letter: Spinal anesthesia and ephedrine in pregnant monkeys.", "content": "Letter: Spinal anesthesia and ephedrine in pregnant monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203451"} {"pmid": "4203452", "title": "The presence and possible significance of cross-reactive antigens in Rhizobium--legume associations.", "content": "The presence and possible significance of cross-reactive antigens in Rhizobium--legume associations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203452"} {"pmid": "4203453", "title": "Proceedings: Netherlands Society for Microbiology meeting at Utrecht on 2 May 1973. Chemotaxis in microorganisms.", "content": "Proceedings: Netherlands Society for Microbiology meeting at Utrecht on 2 May 1973. Chemotaxis in microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203453"} {"pmid": "4203454", "title": "Proceedings: Netherllands Society for Microbiology meeting at Utrecht on 2 May 1973. Environmental effects on bacterial wall synthesis.", "content": "Proceedings: Netherllands Society for Microbiology meeting at Utrecht on 2 May 1973. Environmental effects on bacterial wall synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203454"} {"pmid": "4203456", "title": "Evaluation of 167Tm HEDTA as a bone scanning agent in humans and its comparison with 18F.", "content": "Evaluation of 167Tm HEDTA as a bone scanning agent in humans and its comparison with 18F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203456"} {"pmid": "4203457", "title": "Intra-uterine infection and cord immunoglobulin M. II. Clinical analysis of infants with elevated cord serum immunoglobulin M.", "content": "Intra-uterine infection and cord immunoglobulin M. II. Clinical analysis of infants with elevated cord serum immunoglobulin M. Cord blood immunoglobulin M was measured in 3474 consecutive newborn infants. A group of 147 infants with elevated IgM values (>/=19.0 mg./100 ml.) were compared with 92 unselected newborn infants with normal IgM values. One infant with clinically unsuspected congenital rubella was detected in the study group while no cases of intra-uterine infection were found among the controls. A greater proportion of mothers in the study group had a history of viral infection. The study group also contained a larger number of mothers who might be considered to be at greater risk of infection with agents known to cause intra-uterine disease. Follow-up studies at 6 months of age revealed no differences between the two groups aside from an increased incidence of minor motor abnormalities in the study group. While it is recognized that infants with cord blood IgM levels truly in excess of 30 mg./100 ml. may represent a high-risk group with respect to proved or subclinical intra-uterine infection, it is concluded that routine cord blood screening for elevated IgM values is not a high-yield procedure for the detection of intra-uterine infection in our population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203457"} {"pmid": "4203459", "title": "Strain-dependent teratogenic effects of 1-ethyl-1-nitrosourea in inbred strains of mice.", "content": "Strain-dependent teratogenic effects of 1-ethyl-1-nitrosourea in inbred strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203459"} {"pmid": "4203458", "title": "A comparison of three in vivo assays for cell tumorigenicity.", "content": "A comparison of three in vivo assays for cell tumorigenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203458"} {"pmid": "4203460", "title": "The reaction between carcinoembryonic antigen and concanavalin A.", "content": "The reaction between carcinoembryonic antigen and concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203460"} {"pmid": "4203461", "title": "Differing methodology and equations used in quantitating immunoglobulins by radial immunodiffusion--a comparative evaluation of reported and commercial techniques.", "content": "Differing methodology and equations used in quantitating immunoglobulins by radial immunodiffusion--a comparative evaluation of reported and commercial techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203461"} {"pmid": "4203462", "title": "Letter: Commercial immunodiffusion plates.", "content": "Letter: Commercial immunodiffusion plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203462"} {"pmid": "4203463", "title": "Letter: Non-narcotic buffer for hemoglobin electrophoresis.", "content": "Letter: Non-narcotic buffer for hemoglobin electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203463"} {"pmid": "4203467", "title": "Pharmacologic weakening of extraocular muscles.", "content": "Pharmacologic weakening of extraocular muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203467"} {"pmid": "4203466", "title": "Injection technique for indocyanine green and sodium fluorescein dye angiography of the eye.", "content": "Injection technique for indocyanine green and sodium fluorescein dye angiography of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203466"} {"pmid": "4203468", "title": "A correlation of anatomic and physiologic parameters in the ureter.", "content": "A correlation of anatomic and physiologic parameters in the ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203468"} {"pmid": "4203469", "title": "The relationship of epididymitis to gonorrhea.", "content": "The relationship of epididymitis to gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203469"} {"pmid": "4203470", "title": "Snake venom toxins. The purification and amino acid sequence of toxin TA2 from Dendroaspis angusticeps venom.", "content": "Snake venom toxins. The purification and amino acid sequence of toxin TA2 from Dendroaspis angusticeps venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203470"} {"pmid": "4203474", "title": "Nutritional status of children at Namitambo, Malawi.", "content": "Nutritional status of children at Namitambo, Malawi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203474"} {"pmid": "4203475", "title": "Influence of maximal vasodilatation on glucose and sodium blood-tissue transport in canine heart.", "content": "Influence of maximal vasodilatation on glucose and sodium blood-tissue transport in canine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203475"} {"pmid": "4203476", "title": "Utilization of fructose by a unicellular blue-green alga, Anacystis nidulans.", "content": "Utilization of fructose by a unicellular blue-green alga, Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203476"} {"pmid": "4203477", "title": "Immunosuppressive activity of a heat-stable factor associated with interferon.", "content": "Immunosuppressive activity of a heat-stable factor associated with interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203477"} {"pmid": "4203478", "title": "Mechanisms of ankle injury.", "content": "Mechanisms of ankle injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203478"} {"pmid": "4203471", "title": "Effect of soft tissues on radiographic measurements of the head.", "content": "Effect of soft tissues on radiographic measurements of the head.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203471"} {"pmid": "4203479", "title": "Injuries of the ankle in children.", "content": "Injuries of the ankle in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203479"} {"pmid": "4203480", "title": "Ankle injuries in athletes.", "content": "Ankle injuries in athletes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203480"} {"pmid": "4203481", "title": "Indications for fusion of the ankle.", "content": "Indications for fusion of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203481"} {"pmid": "4203472", "title": "Pathologic response of gingiva to an amino acid increase.", "content": "Pathologic response of gingiva to an amino acid increase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203472"} {"pmid": "4203483", "title": "The use of peripheral veins for alimentation in paediatric patients.", "content": "The use of peripheral veins for alimentation in paediatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203483"} {"pmid": "4203484", "title": "Enteric duplications.", "content": "Enteric duplications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203484"} {"pmid": "4203485", "title": "A human IgA-myeloma protein with anti-streptococcal hyaluronidase (ASH) activity.", "content": "A human IgA-myeloma protein with anti-streptococcal hyaluronidase (ASH) activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203485"} {"pmid": "4203486", "title": "Bovine fibrinogen-induced platelet factor 3 and acid phosphatase availability in human platelets.", "content": "Bovine fibrinogen-induced platelet factor 3 and acid phosphatase availability in human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203486"} {"pmid": "4203473", "title": "Pulp reaction to a polycarboxylate cement in monkeys.", "content": "Pulp reaction to a polycarboxylate cement in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203473"} {"pmid": "4203487", "title": "Chlorinated hydrocarbons in the Sargasso sea atmosphere and surface water.", "content": "Chlorinated hydrocarbons in the Sargasso sea atmosphere and surface water. Polychlorinated biphenyls (PCB), DDT, and chlordane concentrations were measured in air sampled from a tower on the south shore of Bermuda and in Sargasso Sea surface water approximately 80 to 320 kilometers south of Bermuda. The atmospheric chlorinated hydrocarbons appeared to be gaseous, and the DDT concentration was two orders of magnitude higher than previously reported particulate values. The PCB and DDT were enriched in the surface microlayer (150 micrometers) relative to their concentrations in water at a depth of 30 centimeters. Atmospheric residence times for PCB and DDT of 40 to 50 days, calculated from the concentrations in the air and water, are 20 times shorter than values previously estimated for DDT from rainfall and DDT production data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203487"} {"pmid": "4203488", "title": "Nutritional significance of symbiotic bacteria in two species of hemoflagellates.", "content": "Nutritional significance of symbiotic bacteria in two species of hemoflagellates. Symbiote-free strains of Blastocrithidia culicis and Crithidia oncopelti, obtained by chloramphenicol treatment, were compared nutritionally with normal, symbiote-containing strains. The symbiotic bacteria spare the flagellates requirements for exogenous hemin and for other nutritional factors present in liver extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203488"} {"pmid": "4203489", "title": "Cerebroside antibody inhibits sulfatide synthesis and myelination and demyelinates in cord tissue cultures.", "content": "Cerebroside antibody inhibits sulfatide synthesis and myelination and demyelinates in cord tissue cultures. Antiserum to cerebroside was prepared in rabbits by injection of cerebroside together with bovine serum albumin in complete Freund's adjuvant. When applied to cultures of embryo mouse spinal cord at explantation, this antiserum inhibited sulfatide synthesis and myelination; when applied to myelinated cultures it inhibited sulfatide synthesis and produced demyelination. Complement fixation assays also show antibody to cerebroside in serums from rabbits with experimental allergic encephalomyelitis induced by injection of whole white matter. Absorption of such serum with cerebroside abolishes the inhibiting and demyelinating activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203489"} {"pmid": "4203490", "title": "Leptospirosis in Philippine monkeys.", "content": "Leptospirosis in Philippine monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203490"} {"pmid": "4203491", "title": "Ecological distribution of blood parasites in some arboreal rodents.", "content": "Ecological distribution of blood parasites in some arboreal rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203491"} {"pmid": "4203492", "title": "Sarcocystis from rats of Central Java.", "content": "Sarcocystis from rats of Central Java.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203492"} {"pmid": "4203493", "title": "Relationship between liver weight and body weight in normal monkeys and dogs.", "content": "Relationship between liver weight and body weight in normal monkeys and dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203493"} {"pmid": "4203494", "title": "Distribution and metabolism of DDT, carbaryl and methyl parathion in S-and R-strains of Spodoptera littoralis (Boisd).", "content": "Distribution and metabolism of DDT, carbaryl and methyl parathion in S-and R-strains of Spodoptera littoralis (Boisd).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203494"} {"pmid": "4203495", "title": "The administration of monosodium L-glutamate to neonatal and pregnant rhesus monkeys.", "content": "The administration of monosodium L-glutamate to neonatal and pregnant rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203495"} {"pmid": "4203496", "title": "Serum immunoglobulin and complement levels relative to renal homotransplant rejection and patient survival. A retrospective study.", "content": "Serum immunoglobulin and complement levels relative to renal homotransplant rejection and patient survival. A retrospective study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203496"} {"pmid": "4203497", "title": "Infarction of spinal cord and medulla oblongata caused by fibrocartilaginous emboli. Report of a case.", "content": "Infarction of spinal cord and medulla oblongata caused by fibrocartilaginous emboli. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203497"} {"pmid": "4203498", "title": "Ultrastructural and biochemical study of benign ganglioneuroma.", "content": "Ultrastructural and biochemical study of benign ganglioneuroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203498"} {"pmid": "4203499", "title": "\"Vaso-muscular mediadysplasia\" of the arteria vertebralis.", "content": "\"Vaso-muscular mediadysplasia\" of the arteria vertebralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203499"} {"pmid": "4203502", "title": "Case report: Primary (autoimmune?) parathyroiditis.", "content": "Case report: Primary (autoimmune?) parathyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203502"} {"pmid": "4203504", "title": "Effects of insulin on glucose metabolism in vascular and intestinal smooth muscle.", "content": "Effects of insulin on glucose metabolism in vascular and intestinal smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203504"} {"pmid": "4203506", "title": "Standardization of test-negative cream for Brucella milk ring test.", "content": "Standardization of test-negative cream for Brucella milk ring test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203506"} {"pmid": "4203507", "title": "Efficacy of EDTA-tris-lysozyme lavage in the treatment of experimentally in induced Pseudomonas aeruginosa cystitis in the dog.", "content": "Efficacy of EDTA-tris-lysozyme lavage in the treatment of experimentally in induced Pseudomonas aeruginosa cystitis in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203507"} {"pmid": "4203508", "title": "Myocardial contractility in conscious rhesus monkeys: a method for long-term study.", "content": "Myocardial contractility in conscious rhesus monkeys: a method for long-term study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203508"} {"pmid": "4203510", "title": "Parenteral nutrition by total intravenous feeding.", "content": "Parenteral nutrition by total intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203510"} {"pmid": "4203509", "title": "Childhood, juvenile, and adult cerebral lipidoses. Are these different nosological entities?", "content": "Childhood, juvenile, and adult cerebral lipidoses. Are these different nosological entities?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203509"} {"pmid": "4203511", "title": "Toxic and immunological differences among lipopolysaccharides from Thiobacillus ferrooxidans grown autotrophically and heterotrophically.", "content": "Toxic and immunological differences among lipopolysaccharides from Thiobacillus ferrooxidans grown autotrophically and heterotrophically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203511"} {"pmid": "4203512", "title": "Biological production of 5-methylthioribose.", "content": "Biological production of 5-methylthioribose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203512"} {"pmid": "4203513", "title": "The physiology of teichoic acid deficient staphylococci.", "content": "The physiology of teichoic acid deficient staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203513"} {"pmid": "4203514", "title": "The effect of thyroxine and triiodothyronine on bacterial growth.", "content": "The effect of thyroxine and triiodothyronine on bacterial growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203514"} {"pmid": "4203505", "title": "The appearance of some blood-bourne substances during human pregnancy.", "content": "The appearance of some blood-bourne substances during human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203505"} {"pmid": "4203515", "title": "Alkaline phosphatase of Pseudomonas aeruginosa: the mechanism of secretion and release of the enzyme from whole cells.", "content": "Alkaline phosphatase of Pseudomonas aeruginosa: the mechanism of secretion and release of the enzyme from whole cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203515"} {"pmid": "4203516", "title": "Solitary mastocytoma of infancy.", "content": "Solitary mastocytoma of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203516"} {"pmid": "4203517", "title": "The problem of bacteriologically contaminated infant formulas in a newborn nursery.", "content": "The problem of bacteriologically contaminated infant formulas in a newborn nursery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203517"} {"pmid": "4203518", "title": "Plasma norepinephrine and epinephrine in untreated diabetics, during fasting and after insulin administration.", "content": "Plasma norepinephrine and epinephrine in untreated diabetics, during fasting and after insulin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203518"} {"pmid": "4203520", "title": "Lipid and enzyme changes in the blood and liver of monkeys given butylated hydroxytoluene and butylated hydroxyanisole.", "content": "Lipid and enzyme changes in the blood and liver of monkeys given butylated hydroxytoluene and butylated hydroxyanisole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203520"} {"pmid": "4203521", "title": "The formation of carcinogenic nitroso compounds from nitrite and some types of agricultural chemicals.", "content": "The formation of carcinogenic nitroso compounds from nitrite and some types of agricultural chemicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203521"} {"pmid": "4203522", "title": "Studies on the uridine diphosphate-galactose: lipopolysaccharide galactosyltransferase reaction using a fatty acid mutant of Escherichia coli.", "content": "Studies on the uridine diphosphate-galactose: lipopolysaccharide galactosyltransferase reaction using a fatty acid mutant of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203522"} {"pmid": "4203523", "title": "Protein synthesis with messenger ribonucleic acid fractions from membrane-bound and free liver polysomes. Translation characteristics of liver polysomal ribonucleic acids and evidence for albumin production in a messenger-dependent reticulocyte cell-free system.", "content": "Protein synthesis with messenger ribonucleic acid fractions from membrane-bound and free liver polysomes. Translation characteristics of liver polysomal ribonucleic acids and evidence for albumin production in a messenger-dependent reticulocyte cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203523"} {"pmid": "4203524", "title": "Use of benzamidine to prevent the destruction of thyrotropin-releasing hormone (TRH) by blood.", "content": "Use of benzamidine to prevent the destruction of thyrotropin-releasing hormone (TRH) by blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203524"} {"pmid": "4203525", "title": "Thyroglobulin defect in a human congenital goiter.", "content": "Thyroglobulin defect in a human congenital goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203525"} {"pmid": "4203526", "title": "Effect of synthetic luteinizing hormone-releasing hormone (LH-RH) on the release of gonadotropins in hypophyso-gonadal disorders of children and adolescents. 3. Hypopituitarism.", "content": "Effect of synthetic luteinizing hormone-releasing hormone (LH-RH) on the release of gonadotropins in hypophyso-gonadal disorders of children and adolescents. 3. Hypopituitarism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203526"} {"pmid": "4203528", "title": "Role of central monitoring of efference in short-term memory for movements.", "content": "Role of central monitoring of efference in short-term memory for movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203528"} {"pmid": "4203527", "title": "Secondary hypopituitarism: evidence for continuing regulation of hormone release.", "content": "Secondary hypopituitarism: evidence for continuing regulation of hormone release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203527"} {"pmid": "4203529", "title": "Induction of leukemoid disease in mice by Mycoplasma fermentans.", "content": "Induction of leukemoid disease in mice by Mycoplasma fermentans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203529"} {"pmid": "4203530", "title": "Isolation of cores from hepatitis B Dane particles.", "content": "Isolation of cores from hepatitis B Dane particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203530"} {"pmid": "4203531", "title": "Correspondence: Culture of Neisseria gonorrhoeae.", "content": "Correspondence: Culture of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203531"} {"pmid": "4203532", "title": "Congenital toxoplasmosis. Fetal synthesis of oligoclonal immunoglobulin G in intrauterine infection.", "content": "Congenital toxoplasmosis. Fetal synthesis of oligoclonal immunoglobulin G in intrauterine infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203532"} {"pmid": "4203548", "title": "Activation of hepatic microsomal glucuronyl transferase by bilirubin.", "content": "Activation of hepatic microsomal glucuronyl transferase by bilirubin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203548"} {"pmid": "4203549", "title": "Block of oxytocin-induced parturition and oviposition by prostaglandin inhibitors.", "content": "Block of oxytocin-induced parturition and oviposition by prostaglandin inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203549"} {"pmid": "4203554", "title": "Clinical pharmacology of carbenicillin and gentamicin in the neonate and comparative efficacy with ampicillin and gentamicin.", "content": "Clinical pharmacology of carbenicillin and gentamicin in the neonate and comparative efficacy with ampicillin and gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203554"} {"pmid": "4203555", "title": "The influence of hexachlorophene scrubs on the response to placebo or penicillin therapy in impetigo.", "content": "The influence of hexachlorophene scrubs on the response to placebo or penicillin therapy in impetigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203555"} {"pmid": "4203556", "title": "Crystal formation: a new complication of total parenteral nutrition.", "content": "Crystal formation: a new complication of total parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203556"} {"pmid": "4203557", "title": "Increase in the plasma concentration of free tryptophan caused by probenecid in humans.", "content": "Increase in the plasma concentration of free tryptophan caused by probenecid in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203557"} {"pmid": "4203561", "title": "Effect of gold salts and antimalarials on the rheumatoid factor in rheumatoid arthritis.", "content": "Effect of gold salts and antimalarials on the rheumatoid factor in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203561"} {"pmid": "4203562", "title": "Estriol metabolism in the baboon: analysis of urinary and biliary metabolites.", "content": "Estriol metabolism in the baboon: analysis of urinary and biliary metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203562"} {"pmid": "4203563", "title": "G.C. culture evaluation in a community health center. A study of 870 cases.", "content": "G.C. culture evaluation in a community health center. A study of 870 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203563"} {"pmid": "4203564", "title": "Action of some metal ions, EDTA, and heated milk on the milk-clotting process of Penicillium citrinum rennin-like enzyme.", "content": "Action of some metal ions, EDTA, and heated milk on the milk-clotting process of Penicillium citrinum rennin-like enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203564"} {"pmid": "4203566", "title": "The role of fat as a calorie course in parenteral nutrition.", "content": "The role of fat as a calorie course in parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203566"} {"pmid": "4203569", "title": "Heavy metals--toxicity and environmental pollution.", "content": "Heavy metals--toxicity and environmental pollution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203569"} {"pmid": "4203570", "title": "A survey of naturally occurring chelating ligands.", "content": "A survey of naturally occurring chelating ligands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203570"} {"pmid": "4203572", "title": "Clinical effectiveness of lividomycin on urinary tract infections: evaluation with double-blind method.", "content": "Clinical effectiveness of lividomycin on urinary tract infections: evaluation with double-blind method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203572"} {"pmid": "4203573", "title": "Halofenate: an effective hypolipemia- and hypouricemia-inducing drug.", "content": "Halofenate: an effective hypolipemia- and hypouricemia-inducing drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203573"} {"pmid": "4203574", "title": "Use of lorazepam in treating patients with neurotic and somatized psychovegetative symptoms.", "content": "Use of lorazepam in treating patients with neurotic and somatized psychovegetative symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203574"} {"pmid": "4203575", "title": "Molindone: a crossover evaluation of capsule and tablet formulations in severely ill schizophrenic patients.", "content": "Molindone: a crossover evaluation of capsule and tablet formulations in severely ill schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203575"} {"pmid": "4203576", "title": "Amoxapine and imipramine: a double-blind study in depressed patients.", "content": "Amoxapine and imipramine: a double-blind study in depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203576"} {"pmid": "4203577", "title": "A method of pooling data of different rating scales.", "content": "A method of pooling data of different rating scales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203577"} {"pmid": "4203578", "title": "Homoeosis in Drosophila. I. Complementation studies with revertants of Nasobemia.", "content": "Homoeosis in Drosophila. I. Complementation studies with revertants of Nasobemia. A number of homoeotic mutants have been localized to the proximal right arm of chromosome 3 of Drosophila melanogaster. These include seven alleles of Antennapedia (Antp), which is associated with a transformation of antennae into legs; Nasobemia (Ns), which causes the same phenotype as Antp but was considered by Gehring (1966) not to be an allele; and three genes causing a transformation of second and third legs into first legs: Extra sex comb (Scx), Polycomb (Pc), and Multiple sex comb (Msc.). The alleles of Antp and Scx share a common recessive lethal effect, and Pc maps 0.2-0.3 units to the left of Scx.-In the present investigation, rearrangements associated with the reversion of Ns suggest that its cytological location is in or just distal to salivary chromosome doublet 84B1-2. Although Ns is viable when homozygous, four of its revertants share a common recessive lethal effect. These revertants fail to complement the recessive lethality of Antp(B) and Scx. Furthermore, they show a complex pattern of functional interaction with Pc and with Humeral (Hu), a dominant mutation associated with a rearrangement with one breakpoint just distal to 84B1-2. Finally, analysis of a revertant of Msc indicates that Msc is also located very close to 84B1-2. It is concluded that Ns and Scx are alleles of Antp. Pc shows many functional similarities to the Antp locus, but is probably not allelic. Evidence is presented that these dominant homoeotic genes are neomorphic in nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203578"} {"pmid": "4203579", "title": "The interaction of two complex loci, zeste and bithorax in Drosophila melanogaster.", "content": "The interaction of two complex loci, zeste and bithorax in Drosophila melanogaster. It has been found that certain alleles of the zeste locus (z(a) 1-1.0) have no phenotype of their own, but interact with certain alleles at the bithorax locus (bx 3-58.8). This interaction takes the form of an enhancement of the homeotic bx phenotype to a more extreme form-i.e., the metathorax is transformed into mesothorax in varying degrees depending on the bx allele used. This enhancement is somewhat reminiscent of the transvection effect described by Lewis (1954). The characterization of the interaction thus far has shown that the enhancement only effects bx alleles which arise spontaneously, whereas the origin of the z(a) allele is unimportant. The gene claret nondisjunctional was used for the production of gynandromorphs which showed that the enhancing ability of z(a), like the eye pigment change caused by z, is autonomous. The enhancement of one specific allele (bx(34e)), which is temperature-sensitive, has allowed a delineation of the temperature-sensitive period of the bithorax locus to a period extending from the middle of the second larval instar to the middle of the third larval instar. These results, as well as those of other enhancer and suppressor systems in Drosophila, have revealed the possibility of the involvement of heterocyclic compounds in the control of cell determination and fate in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203579"} {"pmid": "4203580", "title": "Patterns of gene variation in central and marginal populations of Drosophila robusta.", "content": "Patterns of gene variation in central and marginal populations of Drosophila robusta. The central and marginal populations of D. robusta differ greatly in the level of inversion polymorphism; the marginal populations are monomorphic or nearly so and the central populations are highly polymorphic. This paper presents the frequencies of alleles at forty gene loci in various populations of D. robusta, studied by electrophoresis of proteins and enzymes. Population samples were obtained from eight widely separated populations of D. robusta which included the central, the extreme marginal and the intervening populations between the center and the margins. We find that the proportion of polymorphic loci and average heterozygosity per individual is slightly higher in the marginal populations than the central populations. In D. robusta on an average, 39% of the loci are polymorphic and the average proportion of loci heterozygous per individual is 11%. A breakdown of loci in three categories, viz, hydrolytic enzymes and some other enzymes, larval proteins and glycolytic and Kreb's cycle enzymes, shows that in all populations the level of polymorphism is highest in the hydrolytic enzymes, intermediate in larval proteins and least in the glycolytic and Kreb's cycle enzymes. On the average, the proportion of loci heterozygous per individual for three groups of loci is: hydrolytic enzymes and others (.164), larval proteins (.115) and glycolytic and Kreb's cycle enzymes (.037). We also observe that in all populations the level of polymorphism on the X chromosome is far less than the expected 38%; in salivary gland cells the euchromatic length of the X chromosome is 38% of the entire genome. Lower levels of polymorphism for the X chromosome loci are explained due to low probability of balanced polymorphisms for the X-linked loci since the conditions for establishment of balanced polymorphism for X-linked loci are more restrictive than for the autosomal loci.-The polymorphic loci can be grouped according to pattern of allele frequencies in different populations as follows: (1) The allele frequencies are similar in all populations at the XDH, Pep-1 and Hex-1 loci. (2) The alleles at the Est-1, Est-2, Amy loci and the AP-4(1.0) and the LAP-1(.90) alleles show north south clinal change in frequency. (3) There is north south and east west differentiation at the Pt-5, Pt-8 and Pt-9 loci and the allele AP-4(.81). (4) Polymorphism at loci such as Fum, B.Ox, Hex-8, Pep-2 and Pep-3 are restricted to only one or two of the populations. (5) Allele frequencies at the MDH and ODH loci fluctuate between populations. (6) Allele frequencies at many polymorphic loci such as Est-1, Est-2, LAP-1, AP-4, Pt-5, Pt-8, Pt-9, Pt-16, MDH, Fum change clinally within a gene arrangement. The pattern of gene variation in D. robusta is very complex and cannot be easily explained due to migration of neutral alleles between once-isolated populations or to semi-isolation of neutral alleles. The observations of the pattern of allele variation in different populations, high levels of polymorphism in the marginal populations which have small population size and low levels of polymorphism of the X chromosome loci all support the argument in favor of balancing selection as the main mechanism for the maintenance of these polymorphisms. Environmental factors must play a role in the maintenance of a great deal of these polymorphisms, since we observe clinal allele frequency changes even within a given inversion type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203580"} {"pmid": "4203581", "title": "Inherited biochemical variation in Drosophila melanogaster: noise or signal? I. Single-locus analysis.", "content": "Inherited biochemical variation in Drosophila melanogaster: noise or signal? I. Single-locus analysis. A study was conducted using small effective population size as an experimental design to test selective neutrality of seven isozyme polymorphisms. Loci varied as to the degree to which the decay of heterozygosity over 21 generations was retarded. Selection for heterozygotes, overdominance, is implicated for at least four of seven loci. Of these ADH gave the largest heterozygote excess in the presence of inbreeding. An interaction between the small population size treatment and excess heterozygosity suggests that (1) the loci studied may be selectively neutral and linked to other loci which are under the influence of selection or (2) the selection coefficients for the loci studied are not independent of the background genotype. In either case four of the seven enzymes studied are signaling the operation of selection. The problem of distinguishing the effect of a single marker from that of a chromosome segment is emphasized. The identification of the genetic unit of selection is crucial to any interpretation of the meaning of enzyme polymorphisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203581"} {"pmid": "4203597", "title": "Diphthericin types, bacteriophage types and serotypes of Corynebacterium diphtheriae strains isolated in Australia.", "content": "Diphthericin types, bacteriophage types and serotypes of Corynebacterium diphtheriae strains isolated in Australia. A dipthericin typing scheme has been constructed using 441 strains of Corynebacterium diptheriae isolated in eastern Australia from 1962 to 1971. Ten types have been distinguished using seven strains of C. diphtheriae and two strains of C. belfanti as indicators of the diphthericins produced by the newly isolated strains. Strains grouped into types L2, L3 and L3a were found only in Melbourne and types L1 and L4 were predominant in Sydney. Type L5 strains were isolated intermittently throughout the period of study and were found in all eastern states. Numerical analysis of the characteristics of the strains suggests that associations exist between, on the one hand, diphthericin type and, on the other hand, bacteriophage type, serotype and biochemical activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203597"} {"pmid": "4203598", "title": "Variation among strains of Coynebacterium diphtheriae during an outbreak in a restricted environment.", "content": "Variation among strains of Coynebacterium diphtheriae during an outbreak in a restricted environment. Strains of Corynebacterium diphtheriae isolated from a small outbreak in the restricted environment of a Mental Hospital were examined. All belonged to one serotype, but there was marked variation in diphthericin type, in sensitivity to bacteriophages and in the minor antigens possessed. One strain was non-virulent and laboratory-produced variants of this non-virulent strain showed changes in some of the characteristics used in the identification and typing of the organism, such as diphthericin type, sensitivity to bacteriophages and diphthericins, virulence, starch fermentation and, to a lesser extent, in antigenic structure. The epidemiological and experimental findings are consistent with the hypothesis that the strains isolated, both in the hospital and in the laboratory, were derivatives of a single parent and the mechanism of some of the variations could be related to changes in some structural component such as the cell membrane or the cell wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203598"} {"pmid": "4203599", "title": "The effect of collagenase-like peptidase from rat testis and clostridial collagenase A on the rat seminal vesicle secretion and its coagulation.", "content": "The effect of collagenase-like peptidase from rat testis and clostridial collagenase A on the rat seminal vesicle secretion and its coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203599"} {"pmid": "4203600", "title": "Stimulation of actinomycin D-binding to eutherian sperm chromatin by reduction of disulphide bonds.", "content": "Stimulation of actinomycin D-binding to eutherian sperm chromatin by reduction of disulphide bonds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203600"} {"pmid": "4203601", "title": "Electron microscopy of human vaginal epithelium under normal and experimental conditions.", "content": "Electron microscopy of human vaginal epithelium under normal and experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203601"} {"pmid": "4203602", "title": "Posttraumatic ossification of the myocardium.", "content": "Posttraumatic ossification of the myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203602"} {"pmid": "4203605", "title": "Malaria in Vietnam (I Corps sector): review of 214 cases including EEG patterns on 19 acutely ill patients.", "content": "Malaria in Vietnam (I Corps sector): review of 214 cases including EEG patterns on 19 acutely ill patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203605"} {"pmid": "4203607", "title": "Case for diagnosis: phaeosporotrichosis.", "content": "Case for diagnosis: phaeosporotrichosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203607"} {"pmid": "4203606", "title": "Management in military blood banking for conservation of blood resources: new aspects concerning the blood donor base.", "content": "Management in military blood banking for conservation of blood resources: new aspects concerning the blood donor base.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203606"} {"pmid": "4203608", "title": "Perspectives in renovascular hypertension.", "content": "Perspectives in renovascular hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203608"} {"pmid": "4203609", "title": "Blast injury of the ear: treatment and evaluation.", "content": "Blast injury of the ear: treatment and evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203609"} {"pmid": "4203610", "title": "Free-living wild animal studies: a stimulus to zoonoses research.", "content": "Free-living wild animal studies: a stimulus to zoonoses research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203610"} {"pmid": "4203611", "title": "Factors related to the retention of naval flight surgeons.", "content": "Factors related to the retention of naval flight surgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203611"} {"pmid": "4203612", "title": "Maxillofacial rehabilitation in South Vietnam.", "content": "Maxillofacial rehabilitation in South Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203612"} {"pmid": "4203613", "title": "Spontaneous rupture of hypernephroma: case report.", "content": "Spontaneous rupture of hypernephroma: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203613"} {"pmid": "4203614", "title": "School counselor: neglected asset in Department of Defense schools.", "content": "School counselor: neglected asset in Department of Defense schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203614"} {"pmid": "4203620", "title": "Synkavit. Radiosensitizing agent in prostatic carcinoma.", "content": "Synkavit. Radiosensitizing agent in prostatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203620"} {"pmid": "4203621", "title": "Histocompatibility testing in intrafamilial renal transplantation.", "content": "Histocompatibility testing in intrafamilial renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203621"} {"pmid": "4203623", "title": "Circulatory effects of splenectomy in the horse. 3. Effect on pulse-work relationship.", "content": "Circulatory effects of splenectomy in the horse. 3. Effect on pulse-work relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203623"} {"pmid": "4203624", "title": "Milk ejection in primiparous heifers in the presence of their calves.", "content": "Milk ejection in primiparous heifers in the presence of their calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203624"} {"pmid": "4203627", "title": "The determination of testosterone in the plasma of calves by radioimmunoassay.", "content": "The determination of testosterone in the plasma of calves by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203627"} {"pmid": "4203629", "title": "Effect of hysterotomy in ewes at different stages of gestation on consequent fertility.", "content": "Effect of hysterotomy in ewes at different stages of gestation on consequent fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203629"} {"pmid": "4203628", "title": "The effects of pitocin and hysterectomy on growth and involution of the corpus luteum of the rabbit.", "content": "The effects of pitocin and hysterectomy on growth and involution of the corpus luteum of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203628"} {"pmid": "4203632", "title": "Localization of measles antibody and inhibitor activity in fractions of human sera at different stages of the disease, and sera of animals immunized with measles virus. I. Dynamics of increase in measles antibody activity and its localization in children sera after natural infection.", "content": "Localization of measles antibody and inhibitor activity in fractions of human sera at different stages of the disease, and sera of animals immunized with measles virus. I. Dynamics of increase in measles antibody activity and its localization in children sera after natural infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203632"} {"pmid": "4203633", "title": "II. Primary and secondary immunological response of experimental animals to attenuated and nonattenuated measles virus.", "content": "II. Primary and secondary immunological response of experimental animals to attenuated and nonattenuated measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203633"} {"pmid": "4203634", "title": "Experimental studies on attenuated measles virus.", "content": "Experimental studies on attenuated measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203634"} {"pmid": "4203637", "title": "Ontogeny of squirrel monkey calls under normal conditions and under acoustic isolation.", "content": "Ontogeny of squirrel monkey calls under normal conditions and under acoustic isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203637"} {"pmid": "4203638", "title": "Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats.", "content": "Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203638"} {"pmid": "4203639", "title": "Urinary excretion of the mycotoxin, sterigmatocystin by vervet monkeys.", "content": "Urinary excretion of the mycotoxin, sterigmatocystin by vervet monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203639"} {"pmid": "4203641", "title": "Evidence of biological kinship using red cell enzyme polymorphisms to supplement the blood groups.", "content": "Evidence of biological kinship using red cell enzyme polymorphisms to supplement the blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203641"} {"pmid": "4203642", "title": "Antitumor activity of constituents of Pseudomonas aeruginosa.", "content": "Antitumor activity of constituents of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203642"} {"pmid": "4203643", "title": "Dietary appraisal of West Bengal pre-school children and its effect on growth and nutrition.", "content": "Dietary appraisal of West Bengal pre-school children and its effect on growth and nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203643"} {"pmid": "4203644", "title": "A histologic follow-up study of free autogenous skin grafts to the alveolar ridge in humans.", "content": "A histologic follow-up study of free autogenous skin grafts to the alveolar ridge in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203644"} {"pmid": "4203645", "title": "The capacity of the parotid glands to concentrate 99mTc from plasma, used as a function test.", "content": "The capacity of the parotid glands to concentrate 99mTc from plasma, used as a function test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203645"} {"pmid": "4203646", "title": "Operative procedures in periapical surgery with contempraneous root filling.", "content": "Operative procedures in periapical surgery with contempraneous root filling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203646"} {"pmid": "4203647", "title": "A study of failures after endodontic surgery by radiographic, histologic and stereomicroscopic methods.", "content": "A study of failures after endodontic surgery by radiographic, histologic and stereomicroscopic methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203647"} {"pmid": "4203648", "title": "A note on the origin of keratocysts of the jaws.", "content": "A note on the origin of keratocysts of the jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203648"} {"pmid": "4203649", "title": "Occurrence of focal epithelial hyperplasia among Amerindians in Ecuador.", "content": "Occurrence of focal epithelial hyperplasia among Amerindians in Ecuador.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203649"} {"pmid": "4203650", "title": "A histologic study of experimentally produced intra-oral odontogenic fistulae in monkeys.", "content": "A histologic study of experimentally produced intra-oral odontogenic fistulae in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203650"} {"pmid": "4203651", "title": "Effect of pupal necrosis upon periodontal healing after surgical injury in rats.", "content": "Effect of pupal necrosis upon periodontal healing after surgical injury in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203651"} {"pmid": "4203652", "title": "Remarkable recurrence of a keratocyst in a bone-graft.", "content": "Remarkable recurrence of a keratocyst in a bone-graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203652"} {"pmid": "4203653", "title": "The treatment of ankylosis in children.", "content": "The treatment of ankylosis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203653"} {"pmid": "4203654", "title": "Influence of mandibular third molars on related supporting tissues.", "content": "Influence of mandibular third molars on related supporting tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203654"} {"pmid": "4203655", "title": "Five cases of hypophosphatasia with dental findings.", "content": "Five cases of hypophosphatasia with dental findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203655"} {"pmid": "4203656", "title": "Lymphangiosarcoma of the gingiva.", "content": "Lymphangiosarcoma of the gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203656"} {"pmid": "4203657", "title": "New metabolic products of Aspergillus flavus. 3. Biosynthesis of asperentin.", "content": "New metabolic products of Aspergillus flavus. 3. Biosynthesis of asperentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203657"} {"pmid": "4203658", "title": "Chloroplast ribosomal RNA genes in the chloroplast DNA of Euglena gracilis.", "content": "Chloroplast ribosomal RNA genes in the chloroplast DNA of Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203658"} {"pmid": "4203659", "title": "A test for nucleotide sequence homology.", "content": "A test for nucleotide sequence homology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203659"} {"pmid": "4203660", "title": "Formation of rings from Drosophila DNA fragments.", "content": "Formation of rings from Drosophila DNA fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203660"} {"pmid": "4203661", "title": "Stability and fine structure of eukaryotic DNA rings in formamide.", "content": "Stability and fine structure of eukaryotic DNA rings in formamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203661"} {"pmid": "4203662", "title": "Proteins in fluid from non-keratinizing jaw cysts. 1. Separation patterns on cellulose acetate membranes and percentage distribution of the electrophoretic fractions.", "content": "Proteins in fluid from non-keratinizing jaw cysts. 1. Separation patterns on cellulose acetate membranes and percentage distribution of the electrophoretic fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203662"} {"pmid": "4203663", "title": "Activity levels of some oxidoreductases of carbohydrate metabolism in leukoplakic and normal human buccal epithelium.", "content": "Activity levels of some oxidoreductases of carbohydrate metabolism in leukoplakic and normal human buccal epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203663"} {"pmid": "4203664", "title": "Thymidine uptake and cell migration in cheek epithelium of zinc-deficient rats.", "content": "Thymidine uptake and cell migration in cheek epithelium of zinc-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203664"} {"pmid": "4203671", "title": "Total parenteral hyperalimentation versus conventional techniques.", "content": "Total parenteral hyperalimentation versus conventional techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203671"} {"pmid": "4203676", "title": "Disulfide bonds of human IgM: differential sensitivity to reductive cleavage.", "content": "Disulfide bonds of human IgM: differential sensitivity to reductive cleavage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203676"} {"pmid": "4203675", "title": "The enrichment of T-cell functions in a lymphocyte population by anti-immunoglobulin columns.", "content": "The enrichment of T-cell functions in a lymphocyte population by anti-immunoglobulin columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203675"} {"pmid": "4203674", "title": "Amyloid fibril protein subunit, \"protein AS\": distribution in tissue and serum in different clinical types of amyloidosis including that associated with myelomatosis and Waldenström's macroglobulinamia.", "content": "Amyloid fibril protein subunit, \"protein AS\": distribution in tissue and serum in different clinical types of amyloidosis including that associated with myelomatosis and Waldenström's macroglobulinamia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203674"} {"pmid": "4203687", "title": "Stimulation of TSH release and glucose oxidation in pituitaries from thyroidectomized rats by thyrotropin releasing factor (TRF).", "content": "Stimulation of TSH release and glucose oxidation in pituitaries from thyroidectomized rats by thyrotropin releasing factor (TRF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203687"} {"pmid": "4203686", "title": "Fracture healing controlled by 87mSr uptake.", "content": "Fracture healing controlled by 87mSr uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203686"} {"pmid": "4203688", "title": "Current status of the cholesterol hypothesis.", "content": "Current status of the cholesterol hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203688"} {"pmid": "4203689", "title": "Chronic meningococcemia in childhood. Case report and review of the literature.", "content": "Chronic meningococcemia in childhood. Case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203689"} {"pmid": "4203692", "title": "Surveillance of elderly hospital patients for pulmonary tuberculosis.", "content": "Surveillance of elderly hospital patients for pulmonary tuberculosis. A restrospective study of pulmonary tuberculosis in a general hospital showed that the diagnosis had been frequently overlooked in the middleaged or elderly because the patient also suffered from a more acute condition which preoccupied the attention of the doctor. The commonest error was to discount chest x-ray abnormalities by omitting sputum culture or serial radiography.Surveillance was carried out on all patients aged 60 or over admitted to a large general hospital whose routine chest radiograph showed signs of possible pulmonary tuberculosis whether apparently active or inactive. Three sputum samples from each patient were examined for Mycobacterium tuberculosis without reference to the clinical presentation. In a nine-month period six out of 81 patients proved to have active pulmonary tuberculosis (7.4%). It is suggested that this may be a useful method of screening the elderly hospital population for pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203692"} {"pmid": "4203695", "title": "The triiodothyronine and thyroxine response to thyrotrophin-releasing hormone in the assessment of the pituitary-thyroid axis.", "content": "The triiodothyronine and thyroxine response to thyrotrophin-releasing hormone in the assessment of the pituitary-thyroid axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203695"} {"pmid": "4203696", "title": "Plasma thyrotrophin and its response to thyrotrophin releasing hormone in endemic goitre.", "content": "Plasma thyrotrophin and its response to thyrotrophin releasing hormone in endemic goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203696"} {"pmid": "4203697", "title": "Attachment formation and separation in heterosexually naive preadult rheus monkeys (Macaca mulatta).", "content": "Attachment formation and separation in heterosexually naive preadult rheus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203697"} {"pmid": "4203699", "title": "Isolation and properties of mutants of the FP2 sex factor of Pseudomonas aeruginosa.", "content": "Isolation and properties of mutants of the FP2 sex factor of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203699"} {"pmid": "4203700", "title": "Genetic and environmental control of a continuous trait, abnormal abdomen, in Drosophila melanogaster.", "content": "Genetic and environmental control of a continuous trait, abnormal abdomen, in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203700"} {"pmid": "4203701", "title": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations.", "content": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203701"} {"pmid": "4203702", "title": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations.", "content": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203702"} {"pmid": "4203693", "title": "Assessment of indirect haemagglutination procedures for the serological diagnosis of bovine brucellosis.", "content": "Assessment of indirect haemagglutination procedures for the serological diagnosis of bovine brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203693"} {"pmid": "4203704", "title": "Mechanism and kinetics of the Haldane effect in human erythrocytes.", "content": "Mechanism and kinetics of the Haldane effect in human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203704"} {"pmid": "4203705", "title": "Kinetic analysis of calcium transport across the placenta.", "content": "Kinetic analysis of calcium transport across the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203705"} {"pmid": "4203694", "title": "Assessment of fluorescent antibody absorption procedures for differentiation of the serological response to Yersinia enterocolitica serotype IX and Brucella abortus in cattle.", "content": "Assessment of fluorescent antibody absorption procedures for differentiation of the serological response to Yersinia enterocolitica serotype IX and Brucella abortus in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203694"} {"pmid": "4203706", "title": "In vivo regional cerebral blood volume by x-ray fluorescence: validation of method.", "content": "In vivo regional cerebral blood volume by x-ray fluorescence: validation of method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203706"} {"pmid": "4203707", "title": "A bidirectional projection between the gracile nucleus and the cerebellum in the dog? An experimental study with tigrolysis and axonal degeneration methods.", "content": "A bidirectional projection between the gracile nucleus and the cerebellum in the dog? An experimental study with tigrolysis and axonal degeneration methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203707"} {"pmid": "4203708", "title": "Peripheral and thoracic duct lymphocyte blastogenesis by T cell specific mitogens in the rhesus monkey.", "content": "Peripheral and thoracic duct lymphocyte blastogenesis by T cell specific mitogens in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203708"} {"pmid": "4203709", "title": "Essential fatty acid studies in primates linolenic acid requirements of capuchins.", "content": "Essential fatty acid studies in primates linolenic acid requirements of capuchins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203709"} {"pmid": "4203710", "title": "Experimental placental detachment in the rhesus monkey: changes in villous ultrastructure.", "content": "Experimental placental detachment in the rhesus monkey: changes in villous ultrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203710"} {"pmid": "4203712", "title": "Some factors affecting the occurence of lead poisoning in captive primates.", "content": "Some factors affecting the occurence of lead poisoning in captive primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203712"} {"pmid": "4203711", "title": "A comparative study of platelet aggregation in primates.", "content": "A comparative study of platelet aggregation in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203711"} {"pmid": "4203713", "title": "Mechanical properties of the primate thorax.", "content": "Mechanical properties of the primate thorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203713"} {"pmid": "4203715", "title": "Commensals and parasites of African baboons (Papio cynocephalus L. 1766) captured in Rift Valley Province of central Kenya.", "content": "Commensals and parasites of African baboons (Papio cynocephalus L. 1766) captured in Rift Valley Province of central Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203715"} {"pmid": "4203714", "title": "Learning in monkeys fed elevated amino acid diets.", "content": "Learning in monkeys fed elevated amino acid diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203714"} {"pmid": "4203717", "title": "Eruption sequence of the deciduous dentition of Papio cynocephalus.", "content": "Eruption sequence of the deciduous dentition of Papio cynocephalus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203717"} {"pmid": "4203716", "title": "Lipid levels in serum, liver and aorta of the vervet monkey.", "content": "Lipid levels in serum, liver and aorta of the vervet monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203716"} {"pmid": "4203718", "title": "Unilateral renal aplasia in the baboon.", "content": "Unilateral renal aplasia in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203718"} {"pmid": "4203720", "title": "Evaluation of the hypothermic action of tetrahydrocannabinols in mice and squirrel monkeys.", "content": "Evaluation of the hypothermic action of tetrahydrocannabinols in mice and squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203720"} {"pmid": "4203719", "title": "The effects of arachidonic acid, prostaglandin E2 and prostaglandin F2alpha on the longitudinal stomach strip of the rat.", "content": "The effects of arachidonic acid, prostaglandin E2 and prostaglandin F2alpha on the longitudinal stomach strip of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203719"} {"pmid": "4203721", "title": "Increase in hepatic blood flow and d-propranolol clearance by glucagon in the monkey.", "content": "Increase in hepatic blood flow and d-propranolol clearance by glucagon in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203721"} {"pmid": "4203722", "title": "Device for the formation of wells in agar gel.", "content": "Device for the formation of wells in agar gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203722"} {"pmid": "4203723", "title": "Medium for the propagation and assay of lactic and other phages.", "content": "Medium for the propagation and assay of lactic and other phages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203723"} {"pmid": "4203730", "title": "IgM serum agglutinators.", "content": "IgM serum agglutinators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203730"} {"pmid": "4203731", "title": "Characterization of subclass-related F(ab)2, Fab-c and Fch fragments obtainined by short papain digestion of human IgG myeloma proteins.", "content": "Characterization of subclass-related F(ab)2, Fab-c and Fch fragments obtainined by short papain digestion of human IgG myeloma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203731"} {"pmid": "4203732", "title": "Instrumental (operant) conditioning of visceral and autonomic functions.", "content": "Instrumental (operant) conditioning of visceral and autonomic functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203732"} {"pmid": "4203735", "title": "Ossifications as a reaction on metal implants.", "content": "Ossifications as a reaction on metal implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203735"} {"pmid": "4203734", "title": "The effect of serotonin on cerebral and extracerebral blood flow with possible implications in migraine.", "content": "The effect of serotonin on cerebral and extracerebral blood flow with possible implications in migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203734"} {"pmid": "4203736", "title": "Studies on electron transport associated with photosystem I. 3. The reduction sites of various Hill oxidants in the photosynthetic electron transport system.", "content": "Studies on electron transport associated with photosystem I. 3. The reduction sites of various Hill oxidants in the photosynthetic electron transport system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203736"} {"pmid": "4203737", "title": "A new polyamine carrier for the immobilization of proteins. Water-insoluble derivatives of pepsin and trypsin.", "content": "A new polyamine carrier for the immobilization of proteins. Water-insoluble derivatives of pepsin and trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203737"} {"pmid": "4203738", "title": "Soyabean lipoxygenase: an iron-containing enzyme.", "content": "Soyabean lipoxygenase: an iron-containing enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203738"} {"pmid": "4203739", "title": "Soya-bean lipoxygenase: an iron-containing dioxygenase.", "content": "Soya-bean lipoxygenase: an iron-containing dioxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203739"} {"pmid": "4203740", "title": "Solubilization and characterization of hepatic bilirubin UDP-glucuronyltransferase.", "content": "Solubilization and characterization of hepatic bilirubin UDP-glucuronyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203740"} {"pmid": "4203741", "title": "Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.", "content": "Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203741"} {"pmid": "4203744", "title": "Immunochemistry of tetanus toxin. The nitration of tyrosyl residues in tetanus toxin.", "content": "Immunochemistry of tetanus toxin. The nitration of tyrosyl residues in tetanus toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203744"} {"pmid": "4203745", "title": "Large-scale preparation of soluble adenovirus hexon, penton and fiber antigens in highly purified form.", "content": "Large-scale preparation of soluble adenovirus hexon, penton and fiber antigens in highly purified form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203745"} {"pmid": "4203752", "title": "Equine infectious anemia: plasma clearance times of passively transferred antibody in foals.", "content": "Equine infectious anemia: plasma clearance times of passively transferred antibody in foals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203752"} {"pmid": "4203753", "title": "Effects of altered ventricular load on the Walton-Brodie strain gauge arch.", "content": "Effects of altered ventricular load on the Walton-Brodie strain gauge arch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203753"} {"pmid": "4203754", "title": "Organ blood flow during pulsatile cardiopulmonary bypass.", "content": "Organ blood flow during pulsatile cardiopulmonary bypass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203754"} {"pmid": "4203766", "title": "Glomerular filtration rate and extracellular fluid volumes during normoglycemia and moderate hyperglycemia in diabetics.", "content": "Glomerular filtration rate and extracellular fluid volumes during normoglycemia and moderate hyperglycemia in diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203766"} {"pmid": "4203767", "title": "Chimerism following fetal transfusion. Report of leucocyte hybridization and infant with acute lymphocytic leukaemia.", "content": "Chimerism following fetal transfusion. Report of leucocyte hybridization and infant with acute lymphocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203767"} {"pmid": "4203769", "title": "Specificity of lymphocytotoxic anti-human antibodies in normal rabbit sera.", "content": "Specificity of lymphocytotoxic anti-human antibodies in normal rabbit sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203769"} {"pmid": "4203770", "title": "Further evidence for HL-A antigens present on adult peripheral red blood cells.", "content": "Further evidence for HL-A antigens present on adult peripheral red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203770"} {"pmid": "4203771", "title": "Anomalous reactivity of certain HL-A typing sera with leukemic lymphocytes.", "content": "Anomalous reactivity of certain HL-A typing sera with leukemic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203771"} {"pmid": "4203775", "title": "Frequency spectrum of optokinetic nystagmus in the normal monkey.", "content": "Frequency spectrum of optokinetic nystagmus in the normal monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203775"} {"pmid": "4203777", "title": "Ecological significance of endosymbiosis: an overall concept.", "content": "Ecological significance of endosymbiosis: an overall concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203777"} {"pmid": "4203768", "title": "Ferredoxins in the evolution of photosynthetic systems from anaerobic bacteria to higher plants.", "content": "Ferredoxins in the evolution of photosynthetic systems from anaerobic bacteria to higher plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203768"} {"pmid": "4203779", "title": "Inhibition of muscle acetoacetate utilization during diabetic ketoacidosis.", "content": "Inhibition of muscle acetoacetate utilization during diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203779"} {"pmid": "4203781", "title": "Elimination of free and protein-bound ionic mercury (20Hg2+) in man.", "content": "Elimination of free and protein-bound ionic mercury (20Hg2+) in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203781"} {"pmid": "4203780", "title": "Divalent cations and the release reaction of pig platelets.", "content": "Divalent cations and the release reaction of pig platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203780"} {"pmid": "4203782", "title": "Inhibition of Neisseria gonorrhoeae by a factor produced by Candida albicans.", "content": "Inhibition of Neisseria gonorrhoeae by a factor produced by Candida albicans. When Candida albicans is present on Transgrow specimens, Neisseria gonorrhoeae is detected less frequently or else can be seen in Gram stains but cannot be readily cultured. When C. albicans and N. gonorrhoeae are grown together on Transgrow, the gonococcal cells die off much more readily than N. gonorrhoeae grown on Transgrow alone. By use of a cross-streaking technique on agar plates, it has been demonstrated that C. albicans produces a soluble substance inhibitory to N. gonorrhoeae, although not to other microorganisms tested. Preliminary results indicate that this inhibitory factor can be extracted by the use of tertiary butanol. Since approximately one-third of the Transgrow specimens with growth contains yeasts, of which C. albicans is by far the most frequent, this factor presents an important complication in the diagnosis of gonorrhea in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203782"} {"pmid": "4203783", "title": "Lysogenic strains of group N lactic streptococci.", "content": "Lysogenic strains of group N lactic streptococci. A temperate bacteriophage, designated r(1)t, was inducible from the group N lactic streptococcus, Streptococcus cremoris R(1), by ultraviolet irradiation or mitomycin C treatment. Induced lysates produced plaques on lawns of three closely related S. cremoris strains, AM(1), SK(11), and US(3). Strain SK(11) was readily lysogenized. S. cremoris AM(1) was the most reliable indicator strain, although the age of the culture used for seeding plates was critical. Zones of lysis but no plaque formation were observed on lawns of nine additional S. cremoris strains. Phage r(1)t could not be detected in filtrates of stationary-phase R(1) cultures and was near the limits of detection in logarithmically growing cultures. Phage levels were still very low (1 plaque-forming unit on AM(1) per 10 induced cells) in induced lysates of R(1) cultures. These low levels of detectable phage may be attributable to an inadequate indicator, lysogenization of the indicator, adsorption of induced phage to cellular debris, concurrent induction of other undetectable phages, or the production of high proportions of defective phages. Electron micrographs of induced R(1) lysates revealed a high incidence of incomplete phage particles, fragments, and ghosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203783"} {"pmid": "4203784", "title": "Morphological observations of Diplodia maydis on synthetic and natural substrates as revealed by scanning electron microscopy.", "content": "Morphological observations of Diplodia maydis on synthetic and natural substrates as revealed by scanning electron microscopy. Mycelial and spore morphology of Diplodia maydis were investigated by using scanning electron microscopy after growth on various media and natural substrates (oat and corn kernels, and corn husks). Of several specimen preparation methods studied, Parducz fixation followed by critical-point or freeze-drying gave adequate preservation for pycnidia, mycelia, and spores. Morphological characteristics were similar in rotary and reciprocal shaker cultures and differed from that found in stationary cultures in the amount of slime-like material produced and precipitated matter on the mycelial surfaces. In general, mycelial surfaces were smooth. Large areas of coalesced material were present in all samples examined. Slime-like material produced in liquid media appeared as a finely laced net, randomly appearing throughout the mycelia with bead-like structures present along the net. A fine netting also was observed interspersed among the spores inside the pycnidia obtained from oats. Slime-like material was observed to cover the pycnidia produced on oat and corn kernels. In the latter case, the spores were less protected by the outer slime-like covering. Thickened node-like structures were observed in mycelial mats produced in modified Fries 2 medium, on potato dextrose agar plates, and on infected oats. Round and ovate thickened node-like structures were observed in mycelium produced on corn kernels. In general, node-like structures were less abundant in mycelia from naturally infected substrates. Conidia were commonly rounded to tapered and two celled, with a distinctive ridged septum at the middle. Dried spores were collapsed in a characteristic flask-like fashion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203784"} {"pmid": "4203785", "title": "Pyocin sensitivity of Pseudomonas species.", "content": "Pyocin sensitivity of Pseudomonas species. Only the fluorescent pseudomonads, Pseudomonas aeruginosa, P. putida, and P. fluorescens, were sensitive to pyocins produced from P. aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203785"} {"pmid": "4203786", "title": "Simplified method for the purification of group A streptococcal M-proteins: solution of the multiple banding problem.", "content": "Simplified method for the purification of group A streptococcal M-proteins: solution of the multiple banding problem. A simple and rapid procedure for the isolation in high yield (about a 30% recovery based on the total 30 to 60% ammonium sulfate recovery) of homogeneous purified group A streptococcal M-protein is described. M-proteins extracted from whole cells of group A streptococci by treatment with hot HCl were neutralized, fractionated with ammonium sulfate, dialyzed, lyophilized, and then subjected to treatment with hot 60% trichloroacetic acid. This was shown to produce an M-protein preparation, free of group A carbohydrate activity and extraneous antigens, in yields up to 10-fold higher than previous methods in about one-fifth the time. These M-protein preparations were shown to: (i) have similar amino acid compositions to their respective type-specific proteins purified by diethylaminoethyl and O-(carboxymethyl) cellulose chromatography, (ii) react with their respective type-specific antisera in Ouchterlony diffusion, (iii) produce antisera in rabbits capable of promoting streptococcal long-chain formation in vitro, and (iv) give only one major band on polyacrylamide gel disk electrophoresis. The data allow for an explanation of the hitherto described multiple banding M-proteins seen on acrylamide electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203786"} {"pmid": "4203787", "title": "Comparison of methods for enumerating fluorescent bacteria.", "content": "Comparison of methods for enumerating fluorescent bacteria. Comparable numbers of fluorescent bacteria may be obtained by either the most-probable-number procedure or by preparing spread plates on modified Henrici agar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203787"} {"pmid": "4203788", "title": "Bacterial culture longevity: control by inorganic phosphate and temperature.", "content": "Bacterial culture longevity: control by inorganic phosphate and temperature. Death of cells in cultures of six species of gram-negative bacteria was accelerated by incorporation in the medium of 10-fold more inorganic phosphate than was needed for growth. Death induced by inorganic phosphate was independent of the carbohydrate employed and was enhanced by warm temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203788"} {"pmid": "4203789", "title": "Medium containing trypan blue and antibiotics for the detection of Cryptococcus neoformans in clinical samples.", "content": "Medium containing trypan blue and antibiotics for the detection of Cryptococcus neoformans in clinical samples. A medium containing trypan blue, gentamicin, and chloramphenicol is introduced for the detection of Cryptococcus neoformans and Cryptococcus species from clinical samples. Ten recently isolated strains of Cryptococcus species as well as several clinical isolates of C. neoformans incorporated trypan blue and produced dark blue colonies on this mycological medium, whereas other common yeasts were light blue. The laboratory diagnosis of two cases of cryptococcosis was accomplished by the isolation of C. neoformans on the antibiotic-dye-containing medium. Compared to conventional media supporting large numbers of Pseudomonas aeruginosa and other gram-negative bacilli, the new medium was selective for yeasts. In one instance, the colonization of the respiratory tract by C. neoformans which led to fungemia was traced by the use of the antibiotic-dye medium. The antibiotic mixture, utilized herein, was more effective in suppressing bacteria contained in samples from patients than a medium containing cycloheximide and chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203789"} {"pmid": "4203790", "title": "Method for performing aerobic plate counts of anhydrous cosmetics utilizing Tween 60 and Arlacel 80 as dispersing agents.", "content": "Method for performing aerobic plate counts of anhydrous cosmetics utilizing Tween 60 and Arlacel 80 as dispersing agents. An aqueous diluent containing Tween 60 and Arlacel 80 gave greater recovery of microorganisms when compared with two common diluents as determined by aerobic plate count of inoculated anhydrous cosmetics. The greater recovery was caused by better dispersion of the anhydrous cosmetics in the diluents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203790"} {"pmid": "4203791", "title": "Eustachian tube function in the rhesus monkey.", "content": "Eustachian tube function in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203791"} {"pmid": "4203792", "title": "Progressive necrotizing otitis. Malignant external otitis.", "content": "Progressive necrotizing otitis. Malignant external otitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203792"} {"pmid": "4203793", "title": "Gene modulation in Drosophila: dosage compensation of Pgd+ and Zw+ genes.", "content": "Gene modulation in Drosophila: dosage compensation of Pgd+ and Zw+ genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203793"} {"pmid": "4203794", "title": "A ribonucleoprotein group with species- and tissue-specific biological activity. II. Tissue-specific action on the transcription and immunological properties of the RNP group.", "content": "A ribonucleoprotein group with species- and tissue-specific biological activity. II. Tissue-specific action on the transcription and immunological properties of the RNP group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203794"} {"pmid": "4203795", "title": "Pharmacology of the inhibition of platelet aggregation.", "content": "Pharmacology of the inhibition of platelet aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203795"} {"pmid": "4203797", "title": "Heterogeneity in combining site specificity of anti-hapten antibodies produced in response to a panosyl-azoprotein conjugate.", "content": "Heterogeneity in combining site specificity of anti-hapten antibodies produced in response to a panosyl-azoprotein conjugate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203797"} {"pmid": "4203801", "title": "Selection for asymmetrical bias in a behavioural character of Drosophila melanogaster.", "content": "Selection for asymmetrical bias in a behavioural character of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203801"} {"pmid": "4203802", "title": "Genetical variation for enzyme activity in a population of Drosophila melanogaster. I. Extent of the variation for alcohol dehydrogenase activity.", "content": "Genetical variation for enzyme activity in a population of Drosophila melanogaster. I. Extent of the variation for alcohol dehydrogenase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203802"} {"pmid": "4203804", "title": "Dynamics of a relationship: rhesus mother-infant ventro-ventral contact.", "content": "Dynamics of a relationship: rhesus mother-infant ventro-ventral contact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203804"} {"pmid": "4203803", "title": "Bladder hyperthermia in the treatment of vesical papillomatosis.", "content": "Bladder hyperthermia in the treatment of vesical papillomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203803"} {"pmid": "4203805", "title": "An experimental continuous-culture unit for the production of frozen concentrated cheese starters.", "content": "An experimental continuous-culture unit for the production of frozen concentrated cheese starters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203805"} {"pmid": "4203806", "title": "Some properties of frozen concentrated starters produced by continuous culture.", "content": "Some properties of frozen concentrated starters produced by continuous culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203806"} {"pmid": "4203807", "title": "In vitro generation of erythropoietic activity by the lysosome-rich fraction of rat kidneys.", "content": "In vitro generation of erythropoietic activity by the lysosome-rich fraction of rat kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203807"} {"pmid": "4203808", "title": "Experimental pyelonephritis in primates.", "content": "Experimental pyelonephritis in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203808"} {"pmid": "4203809", "title": "Regional and subcellular distribution of choline acetyltransferase in the brain of rats.", "content": "Regional and subcellular distribution of choline acetyltransferase in the brain of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203809"} {"pmid": "4203810", "title": "Isolation of an acid-soluble basic protein from monkey brain.", "content": "Isolation of an acid-soluble basic protein from monkey brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203810"} {"pmid": "4203811", "title": "Ceramic-coated subperiosteal implants. I. A pilot study.", "content": "Ceramic-coated subperiosteal implants. I. A pilot study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203811"} {"pmid": "4203812", "title": "Editorial: Data from hospital records.", "content": "Editorial: Data from hospital records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203812"} {"pmid": "4203813", "title": "Laboratory trials on oxamniquine (UK-4271), a candidate schistosomicide.", "content": "Laboratory trials on oxamniquine (UK-4271), a candidate schistosomicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203813"} {"pmid": "4203815", "title": "Letter: Risk with arterial flow probes.", "content": "Letter: Risk with arterial flow probes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203815"} {"pmid": "4203814", "title": "Editorial: New test for Gilbert syndrome.", "content": "Editorial: New test for Gilbert syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203814"} {"pmid": "4203817", "title": "Proceedings: Spectral sensitivity of the cones measured by means of electroretinography.", "content": "Proceedings: Spectral sensitivity of the cones measured by means of electroretinography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203817"} {"pmid": "4203819", "title": "Absence of circulating interferon in patients with malaria and with American trypanosomiasis.", "content": "Absence of circulating interferon in patients with malaria and with American trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203819"} {"pmid": "4203818", "title": "Astrocytic hamartoma of the optic disc in localized ocular neurofibromatosis (von Recklinghausen's disease).", "content": "Astrocytic hamartoma of the optic disc in localized ocular neurofibromatosis (von Recklinghausen's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203818"} {"pmid": "4203820", "title": "Serum IgG aggregates in systemic lupus erythematosus.", "content": "Serum IgG aggregates in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203820"} {"pmid": "4203821", "title": "Effects of microbial flora on levels of colonay stimulating factor in serums of irradiated CFW mice.", "content": "Effects of microbial flora on levels of colonay stimulating factor in serums of irradiated CFW mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203821"} {"pmid": "4203822", "title": "The use of 14C-cyanate as a method for determining erythrocyte survival.", "content": "The use of 14C-cyanate as a method for determining erythrocyte survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203822"} {"pmid": "4203823", "title": "Response of rabbit testicular capsular contractions to testosterone, prostaglandin E1, and isoproterenol in vitro and in vivo.", "content": "Response of rabbit testicular capsular contractions to testosterone, prostaglandin E1, and isoproterenol in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203823"} {"pmid": "4203824", "title": "Spleen and liver responses of protein-depleted rats to dietary egg protein.", "content": "Spleen and liver responses of protein-depleted rats to dietary egg protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203824"} {"pmid": "4203825", "title": "Intramural diverticulosis of the oesophagus.", "content": "Intramural diverticulosis of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203825"} {"pmid": "4203826", "title": "Studies on the enzyme inducing effect of polychlorinated biphenyls.", "content": "Studies on the enzyme inducing effect of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203826"} {"pmid": "4203827", "title": "Application of sequential analysis to Evans blue-carrageenan-induced pleural effusion for screening compounds for anti-inflammatory activity.", "content": "Application of sequential analysis to Evans blue-carrageenan-induced pleural effusion for screening compounds for anti-inflammatory activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203827"} {"pmid": "4203828", "title": "Comparative effect of carbaryl on rat reproduction and guinea pig teratology when fed either in the diet or by stomach intubation.", "content": "Comparative effect of carbaryl on rat reproduction and guinea pig teratology when fed either in the diet or by stomach intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203828"} {"pmid": "4203833", "title": "Comparative studies on Pseudomonas aeruginosa endotoxin.", "content": "Comparative studies on Pseudomonas aeruginosa endotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203833"} {"pmid": "4203835", "title": "Weill-Marchesani syndrome. Growth hormone, thyroid and chromosome studies.", "content": "Weill-Marchesani syndrome. Growth hormone, thyroid and chromosome studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203835"} {"pmid": "4203840", "title": "Mitochondrial nucleic acids.", "content": "Mitochondrial nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203840"} {"pmid": "4203842", "title": "Treatment of acute myelogenous leukemia with 6-MPR.", "content": "Treatment of acute myelogenous leukemia with 6-MPR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203842"} {"pmid": "4203843", "title": "Effects of synthetic salmon calcitonin in osteogenesis imperfecta.", "content": "Effects of synthetic salmon calcitonin in osteogenesis imperfecta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203843"} {"pmid": "4203844", "title": "Epicillin in the treatment of pharyngitis and otitis media.", "content": "Epicillin in the treatment of pharyngitis and otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203844"} {"pmid": "4203845", "title": "Topical treatment with clotrimazole in dermatomycosis.", "content": "Topical treatment with clotrimazole in dermatomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203845"} {"pmid": "4203846", "title": "Loperamide: an open multicentre trial and double-blind cross-over comparison with placebo in patients with chronic diarrhoea.", "content": "Loperamide: an open multicentre trial and double-blind cross-over comparison with placebo in patients with chronic diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203846"} {"pmid": "4203847", "title": "Diethylpropion hydrochloride: an effective appetite suppressant.", "content": "Diethylpropion hydrochloride: an effective appetite suppressant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203847"} {"pmid": "4203848", "title": "Evaluation of EEG and clinical changes associated with pavabid therapy in chronic brain syndrome.", "content": "Evaluation of EEG and clinical changes associated with pavabid therapy in chronic brain syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203848"} {"pmid": "4203849", "title": "A trial of Gerovital H-3 in depression during senility.", "content": "A trial of Gerovital H-3 in depression during senility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203849"} {"pmid": "4203850", "title": "Prediction of neuroleptic effects of CI-686 based on quantitative pharmaco-electroencephalography: drug profiles and dose response curves based on computerized cerebral bio-potentials.", "content": "Prediction of neuroleptic effects of CI-686 based on quantitative pharmaco-electroencephalography: drug profiles and dose response curves based on computerized cerebral bio-potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203850"} {"pmid": "4203851", "title": "Afrodex vs. placebo in the treatment of male impotence: statistical analysis of two double-blind crossover studies.", "content": "Afrodex vs. placebo in the treatment of male impotence: statistical analysis of two double-blind crossover studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203851"} {"pmid": "4203853", "title": "The repair of fractured anterior teeth using an etch technic sealant, and a composite restorative material.", "content": "The repair of fractured anterior teeth using an etch technic sealant, and a composite restorative material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203853"} {"pmid": "4203854", "title": "The structure of dental practice in Connecticut: a summary from the 1971 practice survey.", "content": "The structure of dental practice in Connecticut: a summary from the 1971 practice survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203854"} {"pmid": "4203855", "title": "Musical wind instrumentalists: facial pain and tooth movement.", "content": "Musical wind instrumentalists: facial pain and tooth movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203855"} {"pmid": "4203856", "title": "Yolk proteins in Drosophila: identification and site of synthesis.", "content": "Yolk proteins in Drosophila: identification and site of synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203856"} {"pmid": "4203876", "title": "Fibrinogen derivatives with a higher molecular weight than that of the parent molecule in cord vein plasma of newborns. I. Identification in single plasma samples.", "content": "Fibrinogen derivatives with a higher molecular weight than that of the parent molecule in cord vein plasma of newborns. I. Identification in single plasma samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203876"} {"pmid": "4203884", "title": "Spontaneous perforation of intrathoracic colon following total esophagectomy.", "content": "Spontaneous perforation of intrathoracic colon following total esophagectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203884"} {"pmid": "4203885", "title": "The ultrastructure of striated muscle in malformed chick limb induced by citral.", "content": "The ultrastructure of striated muscle in malformed chick limb induced by citral.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203885"} {"pmid": "4203889", "title": "Fetal hemopoiesis. I. Electron microscopic studies on human yolk sac hemopoiesis.", "content": "Fetal hemopoiesis. I. Electron microscopic studies on human yolk sac hemopoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203889"} {"pmid": "4203891", "title": "Fine structural changes of allergic aspermatogenesis in the guinea pig. I. The similarity in the initial changes induced by passive transfer of anti-testis serum and by immunization with testicular tissue.", "content": "Fine structural changes of allergic aspermatogenesis in the guinea pig. I. The similarity in the initial changes induced by passive transfer of anti-testis serum and by immunization with testicular tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203891"} {"pmid": "4203892", "title": "Fine structural changes of allergic aspermatogenesis in the guinea pig. II. Induced by the homologous parotid gland as antigen.", "content": "Fine structural changes of allergic aspermatogenesis in the guinea pig. II. Induced by the homologous parotid gland as antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203892"} {"pmid": "4203893", "title": "Nephritogenic properties of nephrotoxic guinea pig antibodies. I. Glomerulonephritis induced by guinea pig IgG antibody in rats.", "content": "Nephritogenic properties of nephrotoxic guinea pig antibodies. I. Glomerulonephritis induced by guinea pig IgG antibody in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203893"} {"pmid": "4203897", "title": "The corpus luteum of the rhesus monkey (Macaca mulatta) during late pregnancy. An electron microscopic study.", "content": "The corpus luteum of the rhesus monkey (Macaca mulatta) during late pregnancy. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203897"} {"pmid": "4203898", "title": "In vitro metabolism of palmitic acid and glucose in the developing tissue of the rhesus monkey.", "content": "In vitro metabolism of palmitic acid and glucose in the developing tissue of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203898"} {"pmid": "4203899", "title": "Indomethacin block of normal onset of parturition in primates.", "content": "Indomethacin block of normal onset of parturition in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203899"} {"pmid": "4203900", "title": "Recent developments in radiotherapy.", "content": "Recent developments in radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203900"} {"pmid": "4203901", "title": "The influence of 1-nitro-9(3'-dimethylamino-propylamino)-acridine on biosynthesis of DNA, RNA and protein in synchronized cultures of Euglena Gracilis.", "content": "The influence of 1-nitro-9(3'-dimethylamino-propylamino)-acridine on biosynthesis of DNA, RNA and protein in synchronized cultures of Euglena Gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203901"} {"pmid": "4203903", "title": "Transformation of Bacillus subtilis using gently lysed L-forms; a new mapping technique.", "content": "Transformation of Bacillus subtilis using gently lysed L-forms; a new mapping technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203903"} {"pmid": "4203902", "title": "Zinc, an essential metal ion for beef liver delta-aminolevulinate dehydratase.", "content": "Zinc, an essential metal ion for beef liver delta-aminolevulinate dehydratase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203902"} {"pmid": "4203896", "title": "Quantitative studies on the drainage of the cerebrospinal fluid into the lymphatic system.", "content": "Quantitative studies on the drainage of the cerebrospinal fluid into the lymphatic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203896"} {"pmid": "4203905", "title": "Characterization of a disulfide bridge linking the J chain to the alpha chain of polymeric immunoglobulin A.", "content": "Characterization of a disulfide bridge linking the J chain to the alpha chain of polymeric immunoglobulin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203905"} {"pmid": "4203904", "title": "Identity of the HL-A common portion fragment and human beta2-microglobulin.", "content": "Identity of the HL-A common portion fragment and human beta2-microglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203904"} {"pmid": "4203906", "title": "Enhancement of the biological activities of soybean agglutinin by cross-linking with glutaraldehyde.", "content": "Enhancement of the biological activities of soybean agglutinin by cross-linking with glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203906"} {"pmid": "4203907", "title": "Purification and properties of the hemagglutinin from Sophora japonica seeds.", "content": "Purification and properties of the hemagglutinin from Sophora japonica seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203907"} {"pmid": "4203908", "title": "On the structure of ovotransferrin. I. Isolation and characterization of cyanogen bromide fragments. Reevaluation of the primary structure.", "content": "On the structure of ovotransferrin. I. Isolation and characterization of cyanogen bromide fragments. Reevaluation of the primary structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203908"} {"pmid": "4203909", "title": "3-Phosphoglycerate kinase from rat tissues. Further characterization and developmental studies.", "content": "3-Phosphoglycerate kinase from rat tissues. Further characterization and developmental studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203909"} {"pmid": "4203910", "title": "Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.", "content": "Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203910"} {"pmid": "4203911", "title": "Macroglobulinemia in a child with acute leukemia.", "content": "Macroglobulinemia in a child with acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203911"} {"pmid": "4203912", "title": "Effects of anticoagulants and storage on granulocyte function in bank blood.", "content": "Effects of anticoagulants and storage on granulocyte function in bank blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203912"} {"pmid": "4203913", "title": "Effect of phenobarbitone on bile flow and bilirubin metabolism in man and the rat.", "content": "Effect of phenobarbitone on bile flow and bilirubin metabolism in man and the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203913"} {"pmid": "4203915", "title": "Sherrington was right about the trapezius muscle innervation.", "content": "Sherrington was right about the trapezius muscle innervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203915"} {"pmid": "4203916", "title": "Antihypertensive and central nervous system depressant properties of 3-(gamma-p-fluorobenzoyl propyl) 2,3,4,4a,5,6-hexahydro-1(H)-pyrazino(1,2-a) quinoline hydrochloride (compound 69-183, centpyraquin).", "content": "Antihypertensive and central nervous system depressant properties of 3-(gamma-p-fluorobenzoyl propyl) 2,3,4,4a,5,6-hexahydro-1(H)-pyrazino(1,2-a) quinoline hydrochloride (compound 69-183, centpyraquin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203916"} {"pmid": "4203917", "title": "Studies on phytohemagglutinins XV. Hemagglutinins of the pea and the lentil: advantage of their application in comparison to concanavalin A in some agglutination reactions.", "content": "Studies on phytohemagglutinins XV. Hemagglutinins of the pea and the lentil: advantage of their application in comparison to concanavalin A in some agglutination reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203917"} {"pmid": "4203919", "title": "Thin layer chromatography methods for detecting hippurate hydrolase activity among various bacteria (Pseudomonas, Bacillus, Enterobacteriaceae).", "content": "Thin layer chromatography methods for detecting hippurate hydrolase activity among various bacteria (Pseudomonas, Bacillus, Enterobacteriaceae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203919"} {"pmid": "4203920", "title": "Emergence of bacteria resistant to gentamicin.", "content": "Emergence of bacteria resistant to gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203920"} {"pmid": "4203921", "title": "The efficacy of animal studies in predicting clinical toxicity of cancer chemotherapeutic drugs.", "content": "The efficacy of animal studies in predicting clinical toxicity of cancer chemotherapeutic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203921"} {"pmid": "4203922", "title": "Fate of the T1 strain of Mycoplasma mycoides in cattle following vaccination.", "content": "Fate of the T1 strain of Mycoplasma mycoides in cattle following vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203922"} {"pmid": "4203923", "title": "Susceptibility of mammalian and avian cell cultures to infection with cell-free turkey herpes virus.", "content": "Susceptibility of mammalian and avian cell cultures to infection with cell-free turkey herpes virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203923"} {"pmid": "4203924", "title": "The influence of pH and histidine dipeptides on the production of staphylococcal alpha-toxin.", "content": "The influence of pH and histidine dipeptides on the production of staphylococcal alpha-toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203924"} {"pmid": "4203926", "title": "Microbiological assay for purine analogues with Lactobacillus casei.", "content": "Microbiological assay for purine analogues with Lactobacillus casei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203926"} {"pmid": "4203925", "title": "Formation and properties of protoplasts from antibiotic-producing strains of Penicillium chrysogenum and Cephalosporium acremonium.", "content": "Formation and properties of protoplasts from antibiotic-producing strains of Penicillium chrysogenum and Cephalosporium acremonium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203925"} {"pmid": "4203927", "title": "Localization of a primate-specific esterase using immunofluorescence and immunoperoxidase techniques.", "content": "Localization of a primate-specific esterase using immunofluorescence and immunoperoxidase techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203927"} {"pmid": "4203928", "title": "The co-existence of acoustic neuroma and otosclerosis.", "content": "The co-existence of acoustic neuroma and otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203928"} {"pmid": "4203929", "title": "Comparative immunological and electrophoretic studies on ribosomal proteins of bacillaceae.", "content": "Comparative immunological and electrophoretic studies on ribosomal proteins of bacillaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203929"} {"pmid": "4203930", "title": "Comparison of ribosomal RNA-binding protein \"L2\" isolated from different bacterial species.", "content": "Comparison of ribosomal RNA-binding protein \"L2\" isolated from different bacterial species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203930"} {"pmid": "4203931", "title": "Erythromycin resistant mutants of Bacillus subtilis.", "content": "Erythromycin resistant mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203931"} {"pmid": "4203932", "title": "Chloramphenicol resistant mutants of Bacillus subtilis.", "content": "Chloramphenicol resistant mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203932"} {"pmid": "4203933", "title": "Platinum coordination complexes in cancer chemotherapy.", "content": "Platinum coordination complexes in cancer chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203933"} {"pmid": "4203938", "title": "The effects of airway occlusion after oxygen breathing on the lungs of newborn infants. Radiologic demonstration in the experimental animal.", "content": "The effects of airway occlusion after oxygen breathing on the lungs of newborn infants. Radiologic demonstration in the experimental animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203938"} {"pmid": "4203937", "title": "Peripelvic new bone formation in hemophilia. Report of three cases.", "content": "Peripelvic new bone formation in hemophilia. Report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203937"} {"pmid": "4203941", "title": "A new 10 MeV linear accelerator for radiation therapy.", "content": "A new 10 MeV linear accelerator for radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203941"} {"pmid": "4203942", "title": "The use of ketamine anesthesia in radiation therapy.", "content": "The use of ketamine anesthesia in radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203942"} {"pmid": "4203939", "title": "Weekly total-skin electron-beam irradiation for mycosis fungoides.", "content": "Weekly total-skin electron-beam irradiation for mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203939"} {"pmid": "4203940", "title": "Comparative beam data for the 25 MV betatron, 8, 6, and 4 MV linear accelerators, and 60Co units. Central-axis depth dose, field flatness, and decrement lines.", "content": "Comparative beam data for the 25 MV betatron, 8, 6, and 4 MV linear accelerators, and 60Co units. Central-axis depth dose, field flatness, and decrement lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203940"} {"pmid": "4203943", "title": "Tomography applied to knee arthrography.", "content": "Tomography applied to knee arthrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203943"} {"pmid": "4203944", "title": "Proton radiation therapy.", "content": "Proton radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203944"} {"pmid": "4203945", "title": "Normal and neoplastic tissue effects of high intensity intracavitary irradiation: cancer of the corpus uteri.", "content": "Normal and neoplastic tissue effects of high intensity intracavitary irradiation: cancer of the corpus uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203945"} {"pmid": "4203947", "title": "The kinetics of extracellular protease production in an abnormal sporulation mutant of B. subtilis.", "content": "The kinetics of extracellular protease production in an abnormal sporulation mutant of B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203947"} {"pmid": "4203948", "title": "Quantitative studies on the dissociation equilibrium of HeLa cell ribosomes.", "content": "Quantitative studies on the dissociation equilibrium of HeLa cell ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203948"} {"pmid": "4203950", "title": "Asymptomatic gonorrhea in the male.", "content": "Asymptomatic gonorrhea in the male. In a prospective study, 133 male contacts of 102 women with gonorrhea were examined. A diagnosis of gonorrhea was made in 63 patients, indicating an infection rate of 47% after exposure. Forty-three percent of the patients with gonorrhea were asymptomatic. The duration of the asymptomatic period ranged from 3 to 154 days. The epidemiologic importance of this hidden infectious reservoir is stressed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203950"} {"pmid": "4203951", "title": "Mammalian-lung galactan.", "content": "Mammalian-lung galactan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203951"} {"pmid": "4203949", "title": "Scanning electron microscopic observation of the organ of Corti of the rhesus monkey.", "content": "Scanning electron microscopic observation of the organ of Corti of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203949"} {"pmid": "4203952", "title": "The long-term maintenance treatment of schizophrenic out-patients with depot flupenthixol.", "content": "The long-term maintenance treatment of schizophrenic out-patients with depot flupenthixol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203952"} {"pmid": "4203954", "title": "Human alpha1-antitrypsin.", "content": "Human alpha1-antitrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203954"} {"pmid": "4203955", "title": "Comparison of 115m cadmium retention in rats following different routes of administration.", "content": "Comparison of 115m cadmium retention in rats following different routes of administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203955"} {"pmid": "4203956", "title": "Glomerular ultrafiltration.", "content": "Glomerular ultrafiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203956"} {"pmid": "4203957", "title": "Prostaglandins, calcium metabolism and cancer.", "content": "Prostaglandins, calcium metabolism and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203957"} {"pmid": "4203958", "title": "Competition of the thyroid hormones for binding sites on rat adenohypophyseal proteins in vitro.", "content": "Competition of the thyroid hormones for binding sites on rat adenohypophyseal proteins in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203958"} {"pmid": "4203959", "title": "Pattern formation in the blue-green alga Anabaena. II. Controlled proheterocyst regression.", "content": "Pattern formation in the blue-green alga Anabaena. II. Controlled proheterocyst regression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203959"} {"pmid": "4203960", "title": "Cyclic membrane flow in the ingestive-digestive system of peritrich protozoans. I. Vesicular fusion at the cytopharynx.", "content": "Cyclic membrane flow in the ingestive-digestive system of peritrich protozoans. I. Vesicular fusion at the cytopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203960"} {"pmid": "4203961", "title": "Cyclic membrane flow in the ingestive-digestive system of peritrich protozoans. II. Cup-shaped coated vesicles.", "content": "Cyclic membrane flow in the ingestive-digestive system of peritrich protozoans. II. Cup-shaped coated vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203961"} {"pmid": "4203962", "title": "Further observations on the fine structure of freeze-cleaved tight junctions.", "content": "Further observations on the fine structure of freeze-cleaved tight junctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203962"} {"pmid": "4203963", "title": "Ultrastructural changes in Euglena after ultraviolet irradiation.", "content": "Ultrastructural changes in Euglena after ultraviolet irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203963"} {"pmid": "4203964", "title": "Do lysophospholipids really exist in Tetrahymena pyriformis?", "content": "Do lysophospholipids really exist in Tetrahymena pyriformis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203964"} {"pmid": "4203966", "title": "Contact B-scan ultrasound.", "content": "Contact B-scan ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203966"} {"pmid": "4203967", "title": "Mediastinal ultrasonography.", "content": "Mediastinal ultrasonography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203967"} {"pmid": "4203970", "title": "70mm camera for ultrasound B-scanning.", "content": "70mm camera for ultrasound B-scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203970"} {"pmid": "4203969", "title": "Echocardiographic demonstration of bacterial vegetations in active infective endocarditis.", "content": "Echocardiographic demonstration of bacterial vegetations in active infective endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203969"} {"pmid": "4203968", "title": "Ankle blood pressures in vascular insufficiency involving the legs.", "content": "Ankle blood pressures in vascular insufficiency involving the legs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203968"} {"pmid": "4203971", "title": "Radiolucent intraocular foreign body localization: a case study.", "content": "Radiolucent intraocular foreign body localization: a case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203971"} {"pmid": "4203972", "title": "Digital computer analysis of time-amplitude ultrasonograms from the human eye. I. Signal acquisition.", "content": "Digital computer analysis of time-amplitude ultrasonograms from the human eye. I. Signal acquisition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203972"} {"pmid": "4203973", "title": "Digital computer analysis of time-amplitude ultrasonograms from the human eye. II. Data processing.", "content": "Digital computer analysis of time-amplitude ultrasonograms from the human eye. II. Data processing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203973"} {"pmid": "4203975", "title": "Left atrial mass simulating cardiomyopathy.", "content": "Left atrial mass simulating cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203975"} {"pmid": "4203976", "title": "Echographic aortic valve oriface dimension: its use in evaluating aortic stneosis and cardiac output.", "content": "Echographic aortic valve oriface dimension: its use in evaluating aortic stneosis and cardiac output.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203976"} {"pmid": "4203974", "title": "Ultrasonic diagnostic procedures in obstetrics and gynecology.", "content": "Ultrasonic diagnostic procedures in obstetrics and gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203974"} {"pmid": "4203979", "title": "Training tank: a method for training technicians in ultrasound scanning.", "content": "Training tank: a method for training technicians in ultrasound scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203979"} {"pmid": "4203978", "title": "Real-time cross-sectional ultrasonic imaging of the heart using a linear array multi-element transducer.", "content": "Real-time cross-sectional ultrasonic imaging of the heart using a linear array multi-element transducer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203978"} {"pmid": "4203977", "title": "Gray scale ultrasound.", "content": "Gray scale ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203977"} {"pmid": "4203980", "title": "A sealed test tank for echoscope performance evaluation.", "content": "A sealed test tank for echoscope performance evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203980"} {"pmid": "4203981", "title": "Ultrasound in the diagnosis of liver disease.", "content": "Ultrasound in the diagnosis of liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203981"} {"pmid": "4203982", "title": "Comparison of frog albumins with those of other vertebrates.", "content": "Comparison of frog albumins with those of other vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203982"} {"pmid": "4203983", "title": "Effect of cations on the blood platelet release reaction.", "content": "Effect of cations on the blood platelet release reaction. 1. Stimulus-secretion phenomena in blood platelets incubated with trypsin or thrombin have been investigated.2. Secretion occurs in at least two stages: (a) induction, obtained when the platelets are incubated with proteolytic enzymes in the presence of the chelating agent EDTA, and (b) release, which occurs with the subsequent addition of Ca(2+) to the incubation medium.3. Ca(2+) was the only essential divalent cation required for release. Ba(2+) and Mg(2+) inhibited release and Sr(2+) could only partially substitute for Ca(2+).4. Blood platelets exhibited recovery from enzymic perturbation by trypsin or thrombin by a mechanism that was temperature dependent, but did not require the synthesis of new protein.5. The results are discussed in relationship to stimulus-secretion in other cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203983"} {"pmid": "4203984", "title": "Sarcocystis in the northern fur seal.", "content": "Sarcocystis in the northern fur seal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203984"} {"pmid": "4203988", "title": "Variation with sex of irradiation-induced chromosome damage in somatic cells of Drosophila melanogaster.", "content": "Variation with sex of irradiation-induced chromosome damage in somatic cells of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203988"} {"pmid": "4203989", "title": "Measurement of human placental lactogen with a simple immunodiffusion kit (Plac--Gest).", "content": "Measurement of human placental lactogen with a simple immunodiffusion kit (Plac--Gest).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203989"} {"pmid": "4203991", "title": "Changes of 17-hydroxycorticosteroids and growth hormone during self-stimulation in monkeys.", "content": "Changes of 17-hydroxycorticosteroids and growth hormone during self-stimulation in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203991"} {"pmid": "4203992", "title": "A torque device for studies of primate limb movements.", "content": "A torque device for studies of primate limb movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203992"} {"pmid": "4203993", "title": "Effects of protein-calorie deficiencies on the learning ability of the Wistar rat.", "content": "Effects of protein-calorie deficiencies on the learning ability of the Wistar rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203993"} {"pmid": "4203995", "title": "Blood metabolites in the diagnosis and treatment of diabetes mellitus.", "content": "Blood metabolites in the diagnosis and treatment of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203995"} {"pmid": "4203994", "title": "Emergency management of the patient with seizures. 1. Classification and treatment system, common seizure disorders.", "content": "Emergency management of the patient with seizures. 1. Classification and treatment system, common seizure disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4203994"} {"pmid": "4204000", "title": "Parathyroid hormone effects in rats treated with diphosphonate.", "content": "Parathyroid hormone effects in rats treated with diphosphonate. The ability of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP; 40 milligrams per kilogram of body weight per day) to reduce the hypercalcemic effect of parathyroid hormone in thyroparathyroidectomized rats was confirmed. However, treatment with this large dose of EHDP enhanced the hypophosphatemic effect of a low dose of parathyroid hormone (10 international units per100 grams of body weight), apparently by promoting the renal excretion of phosphate. The data suggest that EHDP may have a direct effect on the renal action of parathyroid hormone and, in this way, may also affect vitamin D metabolism by the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204000"} {"pmid": "4204008", "title": "The incidence of the various biotypes of Brucella abortus in cattle in the south-west of Scotland.", "content": "The incidence of the various biotypes of Brucella abortus in cattle in the south-west of Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204008"} {"pmid": "4204010", "title": "Continuing education for physicians: report of a WHO Expert Committee.", "content": "Continuing education for physicians: report of a WHO Expert Committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204010"} {"pmid": "4204009", "title": "Bovine farmers' lung: a clinical syndrome in a herd of cattle.", "content": "Bovine farmers' lung: a clinical syndrome in a herd of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204009"} {"pmid": "4204012", "title": "On the impulse conducting system of the monkey heart (Macaca mulatta). II. The atrio-ventricular node and bundle.", "content": "On the impulse conducting system of the monkey heart (Macaca mulatta). II. The atrio-ventricular node and bundle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204012"} {"pmid": "4204014", "title": "Immunoglobulins in populations of subtropical and tropical countries.", "content": "Immunoglobulins in populations of subtropical and tropical countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204014"} {"pmid": "4204015", "title": "Critique of the assay and significance of bilirubin conjugation.", "content": "Critique of the assay and significance of bilirubin conjugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204015"} {"pmid": "4204016", "title": "Skin manifestations of meningococcal infection; an immediate indicator of prognosis.", "content": "Skin manifestations of meningococcal infection; an immediate indicator of prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204016"} {"pmid": "4204017", "title": "Autoimmune hemolytic anemia in a 6-week-old infant.", "content": "Autoimmune hemolytic anemia in a 6-week-old infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204017"} {"pmid": "4204018", "title": "An unusual case of childhood chloral hydrate poisoning.", "content": "An unusual case of childhood chloral hydrate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204018"} {"pmid": "4204019", "title": "Treatment of glottic carcinoma by megavoltage radiation therapy and results.", "content": "Treatment of glottic carcinoma by megavoltage radiation therapy and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204019"} {"pmid": "4204020", "title": "Matrix dosemeter to study the uniformity of high energy x-ray beams.", "content": "Matrix dosemeter to study the uniformity of high energy x-ray beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204020"} {"pmid": "4204021", "title": "Zoonotic potential (Rocky Mountain spotted fever aed tularemia) in the Tennessee Valley region. II. Prevalence of Rickettsia rickettsi and Francisella tularensis in mammals and ticks from Land Between the Lakes.", "content": "Zoonotic potential (Rocky Mountain spotted fever aed tularemia) in the Tennessee Valley region. II. Prevalence of Rickettsia rickettsi and Francisella tularensis in mammals and ticks from Land Between the Lakes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204021"} {"pmid": "4204022", "title": "Studies on the sequential immunization against group B arboviruses in squirrel monkeys, cynomolgus monkeys, rhesus monkeys, and chimpanzees.", "content": "Studies on the sequential immunization against group B arboviruses in squirrel monkeys, cynomolgus monkeys, rhesus monkeys, and chimpanzees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204022"} {"pmid": "4204023", "title": "Experimental infections with African Trypanosomes. VI. Glomerulonephritis involving the alternate pathway of complement activation.", "content": "Experimental infections with African Trypanosomes. VI. Glomerulonephritis involving the alternate pathway of complement activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204023"} {"pmid": "4204024", "title": "Response to treatment in man of multi-drug resistant Plasmodium falciparum from Panama.", "content": "Response to treatment in man of multi-drug resistant Plasmodium falciparum from Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204024"} {"pmid": "4204025", "title": "Immunodiagnosis of human trichinosis using counterelectrophoresis and agar gel diffusion techniques.", "content": "Immunodiagnosis of human trichinosis using counterelectrophoresis and agar gel diffusion techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204025"} {"pmid": "4204026", "title": "Schistosoma japonicum infection in monkeys and baboons: parasitological and pathological findings.", "content": "Schistosoma japonicum infection in monkeys and baboons: parasitological and pathological findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204026"} {"pmid": "4204027", "title": "Comparative efficacy of one and two treatments with tubercidin against Schistosomiasis japonica in monkeys.", "content": "Comparative efficacy of one and two treatments with tubercidin against Schistosomiasis japonica in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204027"} {"pmid": "4204028", "title": "Schistosomiasis mansoni in baboons. II. Acquisition of immunity to challenge infection after repeated small exposures to cercariae of Schistosoma mansoni.", "content": "Schistosomiasis mansoni in baboons. II. Acquisition of immunity to challenge infection after repeated small exposures to cercariae of Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204028"} {"pmid": "4204029", "title": "Dermal sensitivity to paracoccidiodin and histoplasmin in family members of patients with paracoccidioidomycosis.", "content": "Dermal sensitivity to paracoccidiodin and histoplasmin in family members of patients with paracoccidioidomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204029"} {"pmid": "4204030", "title": "Zoonotic potential (Rocky Mountain spotted fever and tularemia) in the Tennessee Valley region. I. Ecologic studies of ticks infesting mammals in Land Between the Lakes.", "content": "Zoonotic potential (Rocky Mountain spotted fever and tularemia) in the Tennessee Valley region. I. Ecologic studies of ticks infesting mammals in Land Between the Lakes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204030"} {"pmid": "4204032", "title": "Gold salts in the treatment of rheumatoid arthritis. A double-blind study.", "content": "Gold salts in the treatment of rheumatoid arthritis. A double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204032"} {"pmid": "4204033", "title": "Serum hyperviscosity in Sjögren's syndrome interaction between IgG and IgG rheumatoid factor.", "content": "Serum hyperviscosity in Sjögren's syndrome interaction between IgG and IgG rheumatoid factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204033"} {"pmid": "4204035", "title": "Some factors influencing the chemical composition of mixed rumen bacteria.", "content": "Some factors influencing the chemical composition of mixed rumen bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204035"} {"pmid": "4204034", "title": "The fusion of erythrocytes by fatty acids, esters, retinol and alpha-tocopherol.", "content": "The fusion of erythrocytes by fatty acids, esters, retinol and alpha-tocopherol. 1. The ability of a number of carboxylic acids, their esters, retinol and alpha-tocopherol to induce fusion of hen erythrocytes in vitro was investigated. 2. Some 30 different fat-soluble substances (100mug/ml) were found to cause the formation of multinucleated erythrocytes with a suspension of 3x10(8) erythrocytes/ml. The most effective agents induced fusion within 5-10min at 37 degrees C; some substances required about 1h. 3. Inclusion of Dextran 60C in the test medium minimized colloid osmotic lysis caused by exogenous lipids that induce cell fusion. 4. Cell swelling, followed by cell adhesion, was then seen to precede cell fusion. 5. Fusion occurred with C(10)-C(14) saturated carboxylic acids, with unsaturated, longer-chain carboxylic acids and their mono-esters; retinol, and to a lesser extent alpha-tocopherol, also caused cell fusion. 6. C(6)-C(9), C(15), C(16) and C(18) saturated carboxylic acids did not induce fusion within 4h; glyceryl dioleate was only weakly active, and glyceryl trioleate was inactive in the test system. 7. Fusion was facilitated by a high ratio of chemical agents to cell number and by incubation between pH5 and 6. It was inhibited by EDTA and by serum albumin. 8. Glyceryl mono-oleate caused both a similar fusion of several species of mammalian erythrocyte and the interspecific fusion of human and chicken erythrocytes. 9. The term ;fusogenic' is proposed to describe chemical, viral and physical agents that cause membranes to fuse. 10. The biochemical mechanisms involved and the possible biological significance of membrane fusion by fusogenic lipids are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204034"} {"pmid": "4204031", "title": "Effects of diffuse transcerebral electrical currents on cortical unit potential activity.", "content": "Effects of diffuse transcerebral electrical currents on cortical unit potential activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204031"} {"pmid": "4204046", "title": "Conjugation of bromosulphthalein (BSP) with reduced glutathione in the gastrointestinal tract in vertebrate species.", "content": "Conjugation of bromosulphthalein (BSP) with reduced glutathione in the gastrointestinal tract in vertebrate species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204046"} {"pmid": "4204047", "title": "Abnormal proteins in Drosophila melanogaster subsequent to 5-bromodeoxyuridine administration.", "content": "Abnormal proteins in Drosophila melanogaster subsequent to 5-bromodeoxyuridine administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204047"} {"pmid": "4204048", "title": "Alteration of L-alanine aminotransferase, L-aspartate aminotransferase and beta-hydroxyacyl dehydrogenase activities in Drosophila melanogaster larvae by nutritional manipulation.", "content": "Alteration of L-alanine aminotransferase, L-aspartate aminotransferase and beta-hydroxyacyl dehydrogenase activities in Drosophila melanogaster larvae by nutritional manipulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204048"} {"pmid": "4204049", "title": "The effect of allatectomy on glycogen metabolism in the fat body of the female housefly, Musca domestica L.", "content": "The effect of allatectomy on glycogen metabolism in the fat body of the female housefly, Musca domestica L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204049"} {"pmid": "4204050", "title": "Stimulation of pituitary prolactin and TSH release in lactating and proestrous rats.", "content": "Stimulation of pituitary prolactin and TSH release in lactating and proestrous rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204050"} {"pmid": "4204052", "title": "Cytoplasmic site synthesis of chloroplast aminoacyl-tRNA synthetases in Euglena gracilis.", "content": "Cytoplasmic site synthesis of chloroplast aminoacyl-tRNA synthetases in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204052"} {"pmid": "4204051", "title": "Isolation and characterization of lipoprotein-X (LP-X) from canine.", "content": "Isolation and characterization of lipoprotein-X (LP-X) from canine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204051"} {"pmid": "4204054", "title": "Editorial: Fitting long-term care to the patient's needs.", "content": "Editorial: Fitting long-term care to the patient's needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204054"} {"pmid": "4204053", "title": "Alkaline phosphatase activity associated to a calcium binding glycoprotein from calf scapula cartilage.", "content": "Alkaline phosphatase activity associated to a calcium binding glycoprotein from calf scapula cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204053"} {"pmid": "4204055", "title": "Diagnosis of pulmonary fungous infections.", "content": "Diagnosis of pulmonary fungous infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204055"} {"pmid": "4204056", "title": "Distribution of 125I-prolactin in mice and rats. Studies with whole-body and microautoradiography.", "content": "Distribution of 125I-prolactin in mice and rats. Studies with whole-body and microautoradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204056"} {"pmid": "4204057", "title": "Hemolytic and conglutinating complement in normal and pathologic human sera.", "content": "Hemolytic and conglutinating complement in normal and pathologic human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204057"} {"pmid": "4204058", "title": "Wine in the treatment of long-term geriatric patients in mental institutions.", "content": "Wine in the treatment of long-term geriatric patients in mental institutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204058"} {"pmid": "4204059", "title": "Anderson-Fabry disease: a histopathological study of three cases with observations on the mechanism of production of pain.", "content": "Anderson-Fabry disease: a histopathological study of three cases with observations on the mechanism of production of pain. A clinical review and histopathological study of three cases of Anderson-Fabry disease is presented and pathological changes in the central and peripheral nervous systems are reported, in some sites for the first time. These are telangiectatic changes in vessels of the sympathetic ganglia in the vertebral trunk; storage of glycolipid in pigmented cells of the substantia nigra and in anterior horn cells; and degeneration of nerve fibres in the dorsal root entry zone and substantia gelatinosa of the spinal cord. The histopathological findings suggest that in this disease pain is due to involvement of dorsal root ganglion cells with associated axonal degeneration of the small fibres in pathways subserving pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204059"} {"pmid": "4204060", "title": "Cerebral circulatory and metabolic effects of hypotension produced by deep halothane anaesthesia.", "content": "Cerebral circulatory and metabolic effects of hypotension produced by deep halothane anaesthesia. Hypotension to a mean blood pressure of 33 mmHg for periods of 70 to 187 minutes was induced by increasing the inspired halothane concentration in 11 baboons which were already anaesthetized with 0·5% halothane, nitrous oxide, and oxygen. During hypotension, cerebral blood flow, measured by Xenon clearance and by a carotid electromagnetic flowmeter, decreased by more than half, and sagittal sinus oxygen saturation was 46%. Cerebral oxygen uptake fell from 5·15 to 3·56 ml./100 g/min at this deeper level of halothane anaesthesia. Cerebral hyperaemia developed after hypotension in those animals which regained a mean blood pressure greater than 70 mmHg. Acidbase measurements on CSF from the cisterna magna revealed no metabolic acidosis during or after hypotension. In all four animals with intact autoregulation before hypotension, this was absent or impaired afterwards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204060"} {"pmid": "4204062", "title": "Neurofibromatosis with laryngeal involvement.", "content": "Neurofibromatosis with laryngeal involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204062"} {"pmid": "4204063", "title": "Allelic contracomplementation possible mechanism for initiating sympatric speciation.", "content": "Allelic contracomplementation possible mechanism for initiating sympatric speciation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204063"} {"pmid": "4204064", "title": "Genetically based behaviour patterns in Drosophila melanogaster.", "content": "Genetically based behaviour patterns in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204064"} {"pmid": "4204065", "title": "Immunological reactions in scrapie: the basis of a rapid titration method.", "content": "Immunological reactions in scrapie: the basis of a rapid titration method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204065"} {"pmid": "4204069", "title": "Right ovarian vein syndrome. Six-year critique.", "content": "Right ovarian vein syndrome. Six-year critique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204069"} {"pmid": "4204068", "title": "Monoamine changes in experimental head and spinal cord trauma: failure to confirm previous observations.", "content": "Monoamine changes in experimental head and spinal cord trauma: failure to confirm previous observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204068"} {"pmid": "4204070", "title": "Gigantic traumatic vesical pseudodiverticulum.", "content": "Gigantic traumatic vesical pseudodiverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204070"} {"pmid": "4204071", "title": "Why the monkey? Use of nonhuman primates in urologic research.", "content": "Why the monkey? Use of nonhuman primates in urologic research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204071"} {"pmid": "4204072", "title": "Editorial: Subhuman primates in biomedical research.", "content": "Editorial: Subhuman primates in biomedical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204072"} {"pmid": "4204075", "title": "Cochlear pathology in monkeys exposed to impulse noise.", "content": "Cochlear pathology in monkeys exposed to impulse noise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204075"} {"pmid": "4204076", "title": "The relation between temporary threshold shift and permanent threshold shift in rhesus monkeys exposed to impulse noise.", "content": "The relation between temporary threshold shift and permanent threshold shift in rhesus monkeys exposed to impulse noise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204076"} {"pmid": "4204077", "title": "Deafening effects of impulse noise on the rhesus monkey.", "content": "Deafening effects of impulse noise on the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204077"} {"pmid": "4204078", "title": "The relationship between permanent threshold shift and the loss of hair cells in monkeys exposed to impulse noise.", "content": "The relationship between permanent threshold shift and the loss of hair cells in monkeys exposed to impulse noise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204078"} {"pmid": "4204082", "title": "Photodecomposition of chlorinated biphenyls and dibenzofurans.", "content": "Photodecomposition of chlorinated biphenyls and dibenzofurans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204082"} {"pmid": "4204085", "title": "Trimethoprim in normal and pathological human lung tissue.", "content": "Trimethoprim in normal and pathological human lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204085"} {"pmid": "4204086", "title": "Relative antagonism in vitro of calcium in serum to the bactericidal activities of gentamicin and tobramycin on Pseudomonas aeruginosa.", "content": "Relative antagonism in vitro of calcium in serum to the bactericidal activities of gentamicin and tobramycin on Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204086"} {"pmid": "4204080", "title": "Comparison of arterial lesions and serum lipids in spider and rhesus monkeys on an egg and butter diet.", "content": "Comparison of arterial lesions and serum lipids in spider and rhesus monkeys on an egg and butter diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204080"} {"pmid": "4204087", "title": "The use of oxyphenbutazone ('Tanderil') in acute pelvic inflammatory disease.", "content": "The use of oxyphenbutazone ('Tanderil') in acute pelvic inflammatory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204087"} {"pmid": "4204088", "title": "Triple tetracycline ('Deteclo') as a single dose oral treatment of uncomplicated gonorrhoea in the male.", "content": "Triple tetracycline ('Deteclo') as a single dose oral treatment of uncomplicated gonorrhoea in the male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204088"} {"pmid": "4204089", "title": "Two trials comparing 'Hydergine' with placebo in the treatment of patients suffering from cerebrovascular insufficiency.", "content": "Two trials comparing 'Hydergine' with placebo in the treatment of patients suffering from cerebrovascular insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204089"} {"pmid": "4204090", "title": "A clinical trial comparing 'Hydergine' with placebo in the treatment of cerebrovascular insufficiency in elderly patients.", "content": "A clinical trial comparing 'Hydergine' with placebo in the treatment of cerebrovascular insufficiency in elderly patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204090"} {"pmid": "4204092", "title": "Unaltered glucagon secretion after seven days of sulphonylurea administration in normal subjects.", "content": "Unaltered glucagon secretion after seven days of sulphonylurea administration in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204092"} {"pmid": "4204079", "title": "Comparative lipid response of four primate species to dietary changes in fat and carbohydrate.", "content": "Comparative lipid response of four primate species to dietary changes in fat and carbohydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204079"} {"pmid": "4204091", "title": "Pharmacodynamic aspects of two sulphonylurea derivatives glipizide and glibenclamide.", "content": "Pharmacodynamic aspects of two sulphonylurea derivatives glipizide and glibenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204091"} {"pmid": "4204093", "title": "An open comparative study of the efficacy and tolerance of a new antidiabetic agent: glipizide.", "content": "An open comparative study of the efficacy and tolerance of a new antidiabetic agent: glipizide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204093"} {"pmid": "4204094", "title": "The epidermal ball cell of toad larvae (Bufo b. bufo Linné, Bufo calamita Laurenti).", "content": "The epidermal ball cell of toad larvae (Bufo b. bufo Linné, Bufo calamita Laurenti).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204094"} {"pmid": "4204095", "title": "Clinical aspects of cluster headache.", "content": "Clinical aspects of cluster headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204095"} {"pmid": "4204096", "title": "Rabbit IgG heavy chains: evolutionary divergence of genes coding for constant region.", "content": "Rabbit IgG heavy chains: evolutionary divergence of genes coding for constant region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204096"} {"pmid": "4204097", "title": "Inactivation of trypsin by antibodies of high affinity.", "content": "Inactivation of trypsin by antibodies of high affinity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204097"} {"pmid": "4204098", "title": "Demonstration of rubella IgM antibody by indirect fluorescent antibody staining, sucrose density gradient centrifugation and mercaptoethanol reduction.", "content": "Demonstration of rubella IgM antibody by indirect fluorescent antibody staining, sucrose density gradient centrifugation and mercaptoethanol reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204098"} {"pmid": "4204099", "title": "Effect of diluent on bacterial counts in milk and milk products.", "content": "Effect of diluent on bacterial counts in milk and milk products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204099"} {"pmid": "4204100", "title": "Membranes of mammary gland. 8. Isolation and composition of nuclei and nuclear membrane from bovine mammary gland.", "content": "Membranes of mammary gland. 8. Isolation and composition of nuclei and nuclear membrane from bovine mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204100"} {"pmid": "4204102", "title": "Maturation of the head of bacteriophage T4. I. DNA packaging events.", "content": "Maturation of the head of bacteriophage T4. I. DNA packaging events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204102"} {"pmid": "4204101", "title": "Intrahypothalamic injections of prostaglandins and prostaglandin antagonists and feeding in sheep.", "content": "Intrahypothalamic injections of prostaglandins and prostaglandin antagonists and feeding in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204101"} {"pmid": "4204103", "title": "Fatty acid distribution in lipids and 32P incorporation into phospholipids during early amphibian development.", "content": "Fatty acid distribution in lipids and 32P incorporation into phospholipids during early amphibian development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204103"} {"pmid": "4204104", "title": "Surface ultrastructure of the mucosa of the soft palate in the vervet monkey.", "content": "Surface ultrastructure of the mucosa of the soft palate in the vervet monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204104"} {"pmid": "4204105", "title": "Baboon peripheral lymphocyte response to phytohaemagglutinin.", "content": "Baboon peripheral lymphocyte response to phytohaemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204105"} {"pmid": "4204106", "title": "Routine autoradiography of tissue culture monolayers.", "content": "Routine autoradiography of tissue culture monolayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204106"} {"pmid": "4204107", "title": "Red cell carbonic anhydrases B and C (CA B and CA C).", "content": "Red cell carbonic anhydrases B and C (CA B and CA C).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204107"} {"pmid": "4204108", "title": "Immunization, isolation of immunoglobulins, estimation of antibody titre.", "content": "Immunization, isolation of immunoglobulins, estimation of antibody titre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204108"} {"pmid": "4204109", "title": "Comparison of antigens: the reaction of 'identity'.", "content": "Comparison of antigens: the reaction of 'identity'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204109"} {"pmid": "4204110", "title": "Comparison of antigens: the reaction of partial identity.", "content": "Comparison of antigens: the reaction of partial identity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204110"} {"pmid": "4204111", "title": "Comparison of two regimens of simplified two-stage chemotherapy in previously untreated pulmonary tuberculosis.", "content": "Comparison of two regimens of simplified two-stage chemotherapy in previously untreated pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204111"} {"pmid": "4204113", "title": "Characterization of haemolytic enterococci isolated from oral infections.", "content": "Characterization of haemolytic enterococci isolated from oral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204113"} {"pmid": "4204114", "title": "Susceptibility of haemolytic oral enterococci to eight antibiotics in vitro.", "content": "Susceptibility of haemolytic oral enterococci to eight antibiotics in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204114"} {"pmid": "4204112", "title": "Studies on the treatment of experimental tuberculosis of the guinea pig with intermittent doses of isoniazid.", "content": "Studies on the treatment of experimental tuberculosis of the guinea pig with intermittent doses of isoniazid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204112"} {"pmid": "4204115", "title": "On-line analysis of optokinetic nystagmus by small general purpose digital computer.", "content": "On-line analysis of optokinetic nystagmus by small general purpose digital computer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204115"} {"pmid": "4204116", "title": "Complex formation between macromolecules and drugs. IX. The competition between two sulfa drugs and phenobarbital, pentobarbital or phenoxymethyl penicillin for binding sites on human serum albumin.", "content": "Complex formation between macromolecules and drugs. IX. The competition between two sulfa drugs and phenobarbital, pentobarbital or phenoxymethyl penicillin for binding sites on human serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204116"} {"pmid": "4204121", "title": "Ribosomes in reticulocyte maturation.", "content": "Ribosomes in reticulocyte maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204121"} {"pmid": "4204125", "title": "Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates.", "content": "Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204125"} {"pmid": "4204124", "title": "The role of oligodendroglia and astroglia in Wallerian degeneration of the optic nerve.", "content": "The role of oligodendroglia and astroglia in Wallerian degeneration of the optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204124"} {"pmid": "4204126", "title": "A cingulo-amygdaloid projection in the rhesus monkey.", "content": "A cingulo-amygdaloid projection in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204126"} {"pmid": "4204129", "title": "Radioautographic localization of inhibition of protein synthesis in specific regions of monkey brain.", "content": "Radioautographic localization of inhibition of protein synthesis in specific regions of monkey brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204129"} {"pmid": "4204128", "title": "Visual receptive fields of frontal eye field neurons.", "content": "Visual receptive fields of frontal eye field neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204128"} {"pmid": "4204127", "title": "Studies on the visual area MT in primates. II. Projection fibers to subcortical structures.", "content": "Studies on the visual area MT in primates. II. Projection fibers to subcortical structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204127"} {"pmid": "4204122", "title": "Interconvertible forms of bacterial RNA polymerase.", "content": "Interconvertible forms of bacterial RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204122"} {"pmid": "4204123", "title": "Visualization of genetic transcription.", "content": "Visualization of genetic transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204123"} {"pmid": "4204130", "title": "Firing changes in cells of the nucleus medialis dorsalis associated with delayed response behavior.", "content": "Firing changes in cells of the nucleus medialis dorsalis associated with delayed response behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204130"} {"pmid": "4204131", "title": "Effects of cooling prefrontal cortex on cell firing in the nucleus medialis dorsalis.", "content": "Effects of cooling prefrontal cortex on cell firing in the nucleus medialis dorsalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204131"} {"pmid": "4204133", "title": "Intraoperative coronary collateral function in patients with coronary occlusive disease. Nitroglycerin responsiveness and angiographic correlations.", "content": "Intraoperative coronary collateral function in patients with coronary occlusive disease. Nitroglycerin responsiveness and angiographic correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204133"} {"pmid": "4204132", "title": "Reduction in severity and extent of myocardial infarction when nitroglycerin and methoxamine are administered during coronary occlusion.", "content": "Reduction in severity and extent of myocardial infarction when nitroglycerin and methoxamine are administered during coronary occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204132"} {"pmid": "4204134", "title": "Simultaneous measurement of total and nutritional coronary blood flow in dogs.", "content": "Simultaneous measurement of total and nutritional coronary blood flow in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204134"} {"pmid": "4204135", "title": "Oral treatment in diabetes.", "content": "Oral treatment in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204135"} {"pmid": "4204136", "title": "Diabetic coma.", "content": "Diabetic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204136"} {"pmid": "4204137", "title": "A computer system for interactive processing and evaluation of light stimulated evoked responses.", "content": "A computer system for interactive processing and evaluation of light stimulated evoked responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204137"} {"pmid": "4204138", "title": "The pharmacology of lorazepam, a broad-spectrum tranquillizer.", "content": "The pharmacology of lorazepam, a broad-spectrum tranquillizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204138"} {"pmid": "4204139", "title": "Precipitin reactions between insulin, proinsulin, insulin chains and insulin antibody.", "content": "Precipitin reactions between insulin, proinsulin, insulin chains and insulin antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204139"} {"pmid": "4204140", "title": "Absorption of hemoglobin and hemoglobin iron in alcohol-induced liver injury.", "content": "Absorption of hemoglobin and hemoglobin iron in alcohol-induced liver injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204140"} {"pmid": "4204141", "title": "The method of intraluminal perfusion of the human small intestine. 3. Absorption studies in disease.", "content": "The method of intraluminal perfusion of the human small intestine. 3. Absorption studies in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204141"} {"pmid": "4204142", "title": "Epidemilogy in the undergraduate curriculum of an African medical school.", "content": "Epidemilogy in the undergraduate curriculum of an African medical school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204142"} {"pmid": "4204143", "title": "Auditory delayed matching in the bottlenose dolphin.", "content": "Auditory delayed matching in the bottlenose dolphin. A bottlenose dolphin, already highly proficient in two-choice auditory discriminations, was trained over a nine-day period on auditory delayed matching-to-sample and then tested on 346 unique matching problems, as a function of the delay between the sample and test sounds. Each problem used new sounds and was from five to 10 trials long, with the same sound used as the sample for all trials of a problem. At each trial, the sample was projected underwater for 2.5 sec, followed by a delay and then by a sequence of two 2.5-sec duration test sounds. One of the test sounds matched the sample and was randomly first or second in the sequence, and randomly appeared at either a left or right speaker. Responses to the locus of the matching test sound were reinforced. Over nine, varying-sized blocks of problems, the longest delay of a set of delays in a block was progressively increased from 15 sec initially to a final value of 120 sec. There was a progressive increase across the early blocks in the percentage of correct Trial 1 responses. A ceiling-level of 100% correct responses was then attained over the final six blocks, during which there were 169 successive Trial 1 responses bracketed by two Trial 1 errors (at 24- and 120-sec delays). Performance on trials beyond the first followed a similar trend. Finally, when the sample duration was decreased to 0.2 sec or less, matching performance on Trial 1 of new problems dropped to chance levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204143"} {"pmid": "4204144", "title": "Phagocytosis and processing of bacteria by peritoneal macrophages.", "content": "Phagocytosis and processing of bacteria by peritoneal macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204144"} {"pmid": "4204145", "title": "Efficacy of ribosomal preparations from Pseudomonas aeruginosa to protect against intravenous Pseudomonas challenge in mice.", "content": "Efficacy of ribosomal preparations from Pseudomonas aeruginosa to protect against intravenous Pseudomonas challenge in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204145"} {"pmid": "4204149", "title": "Polychlorinated biphenyls influence on hatchability.", "content": "Polychlorinated biphenyls influence on hatchability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204149"} {"pmid": "4204150", "title": "The metabolism of 14C aflatoxins in laying hens.", "content": "The metabolism of 14C aflatoxins in laying hens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204150"} {"pmid": "4204151", "title": "Increased aflatoxin production by Aspergillus flavus via cobalt irradiation.", "content": "Increased aflatoxin production by Aspergillus flavus via cobalt irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204151"} {"pmid": "4204152", "title": "Influence of polychlorinated biphenyls in the laying hen.", "content": "Influence of polychlorinated biphenyls in the laying hen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204152"} {"pmid": "4204153", "title": "Studies of the chick edema disease. 10. Toxicity of chick edema factors in the chick, chick embryo, and monkey.", "content": "Studies of the chick edema disease. 10. Toxicity of chick edema factors in the chick, chick embryo, and monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204153"} {"pmid": "4204154", "title": "Carriage of Australia antigen by cockroaches.", "content": "Carriage of Australia antigen by cockroaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204154"} {"pmid": "4204155", "title": "Effect of blood factor deposits in reused dialysers on the dialysance of middle weight molecules.", "content": "Effect of blood factor deposits in reused dialysers on the dialysance of middle weight molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204155"} {"pmid": "4204148", "title": "Increased aflatoxin G1 production by Aspergillus flavus via gamma irradiation.", "content": "Increased aflatoxin G1 production by Aspergillus flavus via gamma irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204148"} {"pmid": "4204156", "title": "The production of immunosuppressive antisera.", "content": "The production of immunosuppressive antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204156"} {"pmid": "4204146", "title": "Efficacy of neomycin aerosols in the treatment of burns.", "content": "Efficacy of neomycin aerosols in the treatment of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204146"} {"pmid": "4204158", "title": "Anti-HAA immunity in renal units with a high and low incidence of serum hepatitis.", "content": "Anti-HAA immunity in renal units with a high and low incidence of serum hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204158"} {"pmid": "4204159", "title": "Medical treatment and intrathecal nerve block.", "content": "Medical treatment and intrathecal nerve block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204159"} {"pmid": "4204165", "title": "Propranolol given twice daily in hypertension.", "content": "Propranolol given twice daily in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204165"} {"pmid": "4204166", "title": "The effect of different serum concentrations of antimicrobial drugs on the Lactobacillus leichmannii vitamin B12 assay.", "content": "The effect of different serum concentrations of antimicrobial drugs on the Lactobacillus leichmannii vitamin B12 assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204166"} {"pmid": "4204167", "title": "Memory and the temporal lobe. A review for clinicians.", "content": "Memory and the temporal lobe. A review for clinicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204167"} {"pmid": "4204169", "title": "Structure, synthesis and external transfer of mucosal immunoglobulins.", "content": "Structure, synthesis and external transfer of mucosal immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204169"} {"pmid": "4204170", "title": "Does behavior evolve?", "content": "Does behavior evolve?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204170"} {"pmid": "4204171", "title": "The problem of comparison in comparative psychology.", "content": "The problem of comparison in comparative psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204171"} {"pmid": "4204172", "title": "Problems of comparative psychology.", "content": "Problems of comparative psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204172"} {"pmid": "4204173", "title": "The organization of comparative psychology.", "content": "The organization of comparative psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204173"} {"pmid": "4204174", "title": "Can psychopathology be reinduced in rhesus monkeys?", "content": "Can psychopathology be reinduced in rhesus monkeys?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204174"} {"pmid": "4204175", "title": "Spinal cord injury: a review of experimental implications for clinical prognosis and treatment.", "content": "Spinal cord injury: a review of experimental implications for clinical prognosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204175"} {"pmid": "4204176", "title": "Measurement of liver blood flow in the infant monkey. A comparison of methods.", "content": "Measurement of liver blood flow in the infant monkey. A comparison of methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204176"} {"pmid": "4204177", "title": "Energy metabolism and intravenous nutrition of premature infants. I. The responses of oxygen consumption, respiratory quotient and substrate utilization to infusion of aminosol-glucose.", "content": "Energy metabolism and intravenous nutrition of premature infants. I. The responses of oxygen consumption, respiratory quotient and substrate utilization to infusion of aminosol-glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204177"} {"pmid": "4204178", "title": "Immunoglobulins in haemolytic disease of the newborn.", "content": "Immunoglobulins in haemolytic disease of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204178"} {"pmid": "4204179", "title": "Interaction between serum calcium concentration and glucose tolerance in normal and azotaemic patients.", "content": "Interaction between serum calcium concentration and glucose tolerance in normal and azotaemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204179"} {"pmid": "4204180", "title": "Effect of transplantation site on the results of pancreatic islet isografts in diabetic rats.", "content": "Effect of transplantation site on the results of pancreatic islet isografts in diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204180"} {"pmid": "4204182", "title": "Superficial hemosiderosis of the central nervous system.", "content": "Superficial hemosiderosis of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204182"} {"pmid": "4204184", "title": "Saguinus geoffroyi as a host for Plasmodium vivax.", "content": "Saguinus geoffroyi as a host for Plasmodium vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204184"} {"pmid": "4204185", "title": "Separation of Toxoplasma gondii trophozoites from mouse exudate cells. Comparison of methods.", "content": "Separation of Toxoplasma gondii trophozoites from mouse exudate cells. Comparison of methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204185"} {"pmid": "4204186", "title": "Preliminary observations of Cebus nigrivittatus (Primates: Cebidae) on the Venezuelan Llanos.", "content": "Preliminary observations of Cebus nigrivittatus (Primates: Cebidae) on the Venezuelan Llanos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204186"} {"pmid": "4204187", "title": "Social preference of the squirrel monkey (Saimiri sciureus).", "content": "Social preference of the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204187"} {"pmid": "4204188", "title": "New drugs and research: glybenclamide (Daonil).", "content": "New drugs and research: glybenclamide (Daonil).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204188"} {"pmid": "4204189", "title": "Fontanel size and epiphyseal ossification in neonates with intrauterine growth retardation. Preliminary communication.", "content": "Fontanel size and epiphyseal ossification in neonates with intrauterine growth retardation. Preliminary communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204189"} {"pmid": "4204190", "title": "Digital hypoplasia and anticonvulsants during gestation: a teratogenic syndrome?", "content": "Digital hypoplasia and anticonvulsants during gestation: a teratogenic syndrome?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204190"} {"pmid": "4204181", "title": "Carcinoembryonic antigen (CEA) in feces and plasma of normal subjects and patients with colorectal carcinoma.", "content": "Carcinoembryonic antigen (CEA) in feces and plasma of normal subjects and patients with colorectal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204181"} {"pmid": "4204191", "title": "Hair tissue as a medium for the differential diagnosis of protein-calorie malnutrition: a commentary.", "content": "Hair tissue as a medium for the differential diagnosis of protein-calorie malnutrition: a commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204191"} {"pmid": "4204193", "title": "Design of a cage for breeding and group behavioural studies of Macaca fascicularis.", "content": "Design of a cage for breeding and group behavioural studies of Macaca fascicularis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204193"} {"pmid": "4204192", "title": "Vaccinia virus replication in enucleate BSC-1 cells: particle production and synthesis of viral DNA and proteins.", "content": "Vaccinia virus replication in enucleate BSC-1 cells: particle production and synthesis of viral DNA and proteins. The growth of vaccinia virus in monolayers of BSC-1 cells enucleated by centrifugation in the presence of cytochalasin B has been studied. No evidence for the production of infectious virus in these cells was obtained, and the production of virus particles was reduced to 8.3% compared with the yield from cytochalasin-treated, uncentrifuged cells. Virus DNA and early and late polypeptides were synthesized with normal timing in enucleate cells, but in reduced amounts; cleavage of structural polypeptide precursors P4a and Px also occurred in enucleate cells. Factories containing immature virus particles were demonstrated in enucleate cells by electron microscopy; these factories were reduced in number and size compared with those found in cytochalasin-treated, uncentrifuged cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204192"} {"pmid": "4204194", "title": "Sedation of sheep and patas monkeys with ketamine.", "content": "Sedation of sheep and patas monkeys with ketamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204194"} {"pmid": "4204197", "title": "Medicine and Public Affairs. The 1975 Nixon budget for health.", "content": "Medicine and Public Affairs. The 1975 Nixon budget for health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204197"} {"pmid": "4204196", "title": "Patterns of amyloidosis and their association with plasma-cell dyscrasia, monoclonal immunoglobulins and Bence-Jones proteins.", "content": "Patterns of amyloidosis and their association with plasma-cell dyscrasia, monoclonal immunoglobulins and Bence-Jones proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204196"} {"pmid": "4204201", "title": "Congenital posterior midline pharyngo-esophageal diverticula.", "content": "Congenital posterior midline pharyngo-esophageal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204201"} {"pmid": "4204202", "title": "Synthesis of diphtheria tox-gene products in Escherichia coli extracts.", "content": "Synthesis of diphtheria tox-gene products in Escherichia coli extracts. In a protein-synthesizing system extracted from E. coli, purified DNA from corynephages betac(tox+) and beta45c was used to direct the in vitro synthesis of diphtheria toxin and of the related nontoxic protein, CRM45, as well as of other beta-phage proteins. When betac(tox+)-DNA or betac-DNA was added to a similar system extracted from the nonlysogenic Corynebacterium diphtheriae strain, C7(s)(-)(tox-), neither toxin nor the CRM45 protein was produced, although other beta-phage proteins were synthesized in amounts equivalent to those produced in the E. coli system from the same amount of beta-phage DNA. Preliminary experiments suggest that both toxinogenic and nontoxinogenic strains of the diphtheria bacillus contain a factor that specificially blocks expression of the tox gene. Synthesis of toxin and the CRM45 protein in the E. coli system could not be inhibited by relatively high concentrations of inorganic iron, but could be inhibited by extracts from the C7(s)(-)(tox-) strain of C. diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204202"} {"pmid": "4204205", "title": "Treatment of aspergillosis with emetine hydrochloride.", "content": "Treatment of aspergillosis with emetine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204205"} {"pmid": "4204203", "title": "Mechanism of DNA replication in Drosophila chromosomes: structure of replication forks and evidence for bidirectionality.", "content": "Mechanism of DNA replication in Drosophila chromosomes: structure of replication forks and evidence for bidirectionality. The replicating chromosomal DNA in Drosophila melanogaster cleavage nuclei has been visualized in the electron microscope as a serial array of closely spaced replicated regions created by pairs of diverging replication forks. The fine structure of the forks is very similar to that observed for the replication forks of bidirectionally replicating bacteriophage DNAs. However, the mean length of the single-stranded gaps in Drosophila forks is less than 200 nucleotide residues, much shorter than the gaps in phage forks. This difference in gap length corresponds to the observed difference in the size of Okazaki fragments from Drosophila and phage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204203"} {"pmid": "4204204", "title": "Calf tendon procollagen peptidase: its purification and endopeptidase mode of action.", "content": "Calf tendon procollagen peptidase: its purification and endopeptidase mode of action. The procollagen peptidase activity of calf tendon has been purified. The enzyme has a high degree of specificity for native procollagen and converts both pro alpha1 and alpha2, to alpha1 and alpha2, respectively. The purified enzyme is an endopeptidase which excises the amino terminal peptide extensions of the precursor chains in block; the molecular size and amino-acid composition of the excised peptides compare favorably with those predicted in previous reports. Antisera to the enzyme and to procollagen have been prepared and have been used to characterize the enzyme, the enzymatically excised peptides, and the enzyme-peptide complex in reaction mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204204"} {"pmid": "4204206", "title": "Mapping human autosomes: evidence supporting assignment of rhesus to the short arm of chromosome No. 1.", "content": "Mapping human autosomes: evidence supporting assignment of rhesus to the short arm of chromosome No. 1. Rh-negative erythrocytes were found in the blood of an Rh-positive man suffering from myelofibrosis. Nucleated hemopoietic precursors were also circulating in his blood, and these cells had an abnormal chromosome complement from which identifiable chromosome segments had been deleted. Correlation of the serological and cytogenetic findings, combined with previous data, indicates that the Rhesus blood group locus is on the distal portion of the short arm of chromosome No. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204206"} {"pmid": "4204207", "title": "Otorhinolaryngology.", "content": "Otorhinolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204207"} {"pmid": "4204209", "title": "Cortisone influences developing collaterals. 1. A morphologic study.", "content": "Cortisone influences developing collaterals. 1. A morphologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204209"} {"pmid": "4204210", "title": "Electron microscopic findings of human auricular appendages.", "content": "Electron microscopic findings of human auricular appendages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204210"} {"pmid": "4204211", "title": "Suppression of experimental allergic thyroiditis in guinea pigs by homologeous and heterologeous thyroglobulin.", "content": "Suppression of experimental allergic thyroiditis in guinea pigs by homologeous and heterologeous thyroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204211"} {"pmid": "4204212", "title": "Attempt to visualise the ventricular conduction system intravitam. Radiologic in vitro visualisation of the left ventricular conduction system in cow, calf and sheep hearts.", "content": "Attempt to visualise the ventricular conduction system intravitam. Radiologic in vitro visualisation of the left ventricular conduction system in cow, calf and sheep hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204212"} {"pmid": "4204216", "title": "Delayed, in vivo hepatic postmorten autolysis. II. Morphological changes in reticulo-endothelial cells.", "content": "Delayed, in vivo hepatic postmorten autolysis. II. Morphological changes in reticulo-endothelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204216"} {"pmid": "4204217", "title": "The distortion and disorganization of the glomerulus in progressive Masugi nephritis in the rat.", "content": "The distortion and disorganization of the glomerulus in progressive Masugi nephritis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204217"} {"pmid": "4204221", "title": "Giant mitochondria. II. Induction of matrix enriched megamitochondria in mouse liver parenchymal cells by ethidium bromide.", "content": "Giant mitochondria. II. Induction of matrix enriched megamitochondria in mouse liver parenchymal cells by ethidium bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204221"} {"pmid": "4204225", "title": "Innovative methods of expanding ambulatory services.", "content": "Innovative methods of expanding ambulatory services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204225"} {"pmid": "4204227", "title": "Carbon nuclear magnetic resonance studies of the histidine residue in alpha-lytic protease. Implications for the catalytic mechanism of serine proteases.", "content": "Carbon nuclear magnetic resonance studies of the histidine residue in alpha-lytic protease. Implications for the catalytic mechanism of serine proteases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204227"} {"pmid": "4204228", "title": "Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey.", "content": "Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204228"} {"pmid": "4204230", "title": "The neuronographic and metric study of the dendritic arbours of neurons in the motor cortex of Macaca mulatta at birth and at 24 months of age.", "content": "The neuronographic and metric study of the dendritic arbours of neurons in the motor cortex of Macaca mulatta at birth and at 24 months of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204230"} {"pmid": "4204229", "title": "The propagation of focal paroxysmal activity in the Macaca mulatta at birth and at 24 months.", "content": "The propagation of focal paroxysmal activity in the Macaca mulatta at birth and at 24 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204229"} {"pmid": "4204231", "title": "The role of the postcentral gyrus in the tactile crossed placing reaction in the Rhesus monkey.", "content": "The role of the postcentral gyrus in the tactile crossed placing reaction in the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204231"} {"pmid": "4204232", "title": "Mutagenicity of derivatives of the oncogenic purine N-oxides.", "content": "Mutagenicity of derivatives of the oncogenic purine N-oxides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204232"} {"pmid": "4204233", "title": "Effects of an elemental diet on human fecal flora.", "content": "Effects of an elemental diet on human fecal flora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204233"} {"pmid": "4204234", "title": "Longevity therapy with chronic patients in a state hospital.", "content": "Longevity therapy with chronic patients in a state hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204234"} {"pmid": "4204235", "title": "Preparation of sphaeroplasts from Lactobacillus casei by growth with low concentration of benzylpenicillin.", "content": "Preparation of sphaeroplasts from Lactobacillus casei by growth with low concentration of benzylpenicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204235"} {"pmid": "4204236", "title": "R-factor mediated resistance to penicillins which does not involve a beta-lactamase.", "content": "R-factor mediated resistance to penicillins which does not involve a beta-lactamase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204236"} {"pmid": "4204237", "title": "The slime of Pseudomonas aeruginosa: biological characterization and possible role in experimental infection.", "content": "The slime of Pseudomonas aeruginosa: biological characterization and possible role in experimental infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204237"} {"pmid": "4204238", "title": "Diphtheria in the United States, 1959-1970.", "content": "Diphtheria in the United States, 1959-1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204238"} {"pmid": "4204239", "title": "Experimental studies of rhesus monkeys infected with epizootic and enzootic subtypes of Venezuelan equine encephalitis virus.", "content": "Experimental studies of rhesus monkeys infected with epizootic and enzootic subtypes of Venezuelan equine encephalitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204239"} {"pmid": "4204241", "title": "Immunochemical evidence for the transport of haemolymph protein into the cuticle of Manduca sexta.", "content": "Immunochemical evidence for the transport of haemolymph protein into the cuticle of Manduca sexta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204241"} {"pmid": "4204240", "title": "Antigen-negative meningitis due to group A Neisseria meningitidis.", "content": "Antigen-negative meningitis due to group A Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204240"} {"pmid": "4204242", "title": "Cathepsin D of rabbit skin: an immunoenzymic study.", "content": "Cathepsin D of rabbit skin: an immunoenzymic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204242"} {"pmid": "4204243", "title": "Elevated antihemophilic factor (AHF, factor VIII) procoagulant activity and AHF-like antigen in alcoholic cirrhosis of the liver.", "content": "Elevated antihemophilic factor (AHF, factor VIII) procoagulant activity and AHF-like antigen in alcoholic cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204243"} {"pmid": "4204244", "title": "Antibody-dependent cellular cytotoxicity to a syngeneic Gross virus-induced lymphoma.", "content": "Antibody-dependent cellular cytotoxicity to a syngeneic Gross virus-induced lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204244"} {"pmid": "4204245", "title": "Nonspecific suppression of tumor growth by an immune reaction to Listeria monocytogenes.", "content": "Nonspecific suppression of tumor growth by an immune reaction to Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204245"} {"pmid": "4204247", "title": "Surface pH changes during and after myocardial ischemia in primates.", "content": "Surface pH changes during and after myocardial ischemia in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204247"} {"pmid": "4204246", "title": "Triglyceride secretion rates: use of Triton WR 1339 in the rhesus monkey.", "content": "Triglyceride secretion rates: use of Triton WR 1339 in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204246"} {"pmid": "4204248", "title": "Sources of gram-negative infection after open-heart surgery.", "content": "Sources of gram-negative infection after open-heart surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204248"} {"pmid": "4204250", "title": "Factors influencing the adsorption of bacteriophage 2 to cells of Pseudomonas aeruginosa.", "content": "Factors influencing the adsorption of bacteriophage 2 to cells of Pseudomonas aeruginosa. Phage 2 adsorbed to Pseudomonas aeruginosa strain BI in 5 mM Tris buffer, providing that cations like Na(+), Mg(2+), or Ca(2+) were present. Adsorption was observed over a broad pH range, reaching a maximum level around pH 7.5, which coincided with the pH required for maximal activity of the phage 2-associated slime polysaccharide depolymerase. Mutants of strain BI and other strains of P. aeruginosa possessing slime layers that were devoid of phage 2 depolymerase substrate were incapable of adsorbing phage 2. On the other hand, those strains containing substrate for the phage 2 depolymerase in the slime layer were capable of adsorbing phage 2. The same relationship of phage depolymerase-substrate interaction to phage adsorption was observed with Pseudomonas phage 8, which possesses a depolymerase that differs in its specificity from the phage 2 depolymerase. The receptor-like activity of purified slime containing the specific substrate for the phage-associated depolymerase was demonstrable by its ability to inactivate phage. However, receptor-like activity or phage inactivation was not observed with those slimes that were devoid of the depolymerase substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204250"} {"pmid": "4204249", "title": "Analysis of bacteriophage phi 29 gene function: protein synthesis in suppressor-sensitive mutant infection of Bacillus subtilis.", "content": "Analysis of bacteriophage phi 29 gene function: protein synthesis in suppressor-sensitive mutant infection of Bacillus subtilis. Phage phi29 suppressor-sensitive (sus) mutants of 14 cistrons have been examined for production of (14)C-labeled viral-specific proteins in restrictive infections of Bacillus subtilis. Proteins specified by four cistrons (H, J, L, and N) have been resolved and identified by sodium dodecyl sulfate gel electrophoresis and autoradiography, and fragments of the normal polypeptides were detected. Mutants of six cistrons (C, D, E, F, I, and M) demonstrated two or more missing bands in the gel profiles, and thus some of these gene products may have regulatory functions. Mutation was detected in at least five genes coding for low-molecular-weight proteins, but a conditionally lethal mutant in only one of these genes has been isolated. Preliminary evidence that a precursor protein is cleaved to generate the neck appendage structural protein and a low-molecular-weight product has been obtained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204249"} {"pmid": "4204251", "title": "Bacteriuria and oral contraceptives. Routine health examinations of 12,076 middle-class women.", "content": "Bacteriuria and oral contraceptives. Routine health examinations of 12,076 middle-class women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204251"} {"pmid": "4204253", "title": "Comparison of phototrap complexes from chromatophores of Rhodospirillum rubrum, Rhodopseudomonas spheroides, and the R-26 mutant of Rhodopseudomonas spheroides.", "content": "Comparison of phototrap complexes from chromatophores of Rhodospirillum rubrum, Rhodopseudomonas spheroides, and the R-26 mutant of Rhodopseudomonas spheroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204253"} {"pmid": "4204254", "title": "Protection by histidine from inactivation of DNA transforming activity by near-ultraviolet light (365 nm) compared with far-ultraviolet light (254 nm).", "content": "Protection by histidine from inactivation of DNA transforming activity by near-ultraviolet light (365 nm) compared with far-ultraviolet light (254 nm).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204254"} {"pmid": "4204257", "title": "Naproxen-metabolism, excretion and comparative pharmacokinetics.", "content": "Naproxen-metabolism, excretion and comparative pharmacokinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204257"} {"pmid": "4204256", "title": "Comparative toxicology of naproxen.", "content": "Comparative toxicology of naproxen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204256"} {"pmid": "4204266", "title": "Nonspecific agents acting on parasites: synergistic effect of nitrogen mustard and acriflavine on resistance formation.", "content": "Nonspecific agents acting on parasites: synergistic effect of nitrogen mustard and acriflavine on resistance formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204266"} {"pmid": "4204267", "title": "The effect of dietary protein depletion on immunocompetence: the importance of nutritional repletion prior to immunologic induction.", "content": "The effect of dietary protein depletion on immunocompetence: the importance of nutritional repletion prior to immunologic induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204267"} {"pmid": "4204269", "title": "Parenteral nutrition in the burned child: a study of twenty-six patients.", "content": "Parenteral nutrition in the burned child: a study of twenty-six patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204269"} {"pmid": "4204268", "title": "Bacterial endocarditis associated with colorectal carcinoma.", "content": "Bacterial endocarditis associated with colorectal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204268"} {"pmid": "4204270", "title": "Behaviour of an aziridine alkylating agent in acid solution.", "content": "Behaviour of an aziridine alkylating agent in acid solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204270"} {"pmid": "4204271", "title": "Aspartate transcarbamylase from Streptococcus faecalis. Purification, properties, and nature of an allosteric activator site.", "content": "Aspartate transcarbamylase from Streptococcus faecalis. Purification, properties, and nature of an allosteric activator site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204271"} {"pmid": "4204272", "title": "Aspartate transcarbamylase from Streptococcus faecalis. Reverse reaction and binding studies.", "content": "Aspartate transcarbamylase from Streptococcus faecalis. Reverse reaction and binding studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204272"} {"pmid": "4204273", "title": "Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site.", "content": "Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204273"} {"pmid": "4204274", "title": "Allosteric effectors of hemoglobin. Interaction of human adult and fetal hemoglobins with poly(carboxylic acids).", "content": "Allosteric effectors of hemoglobin. Interaction of human adult and fetal hemoglobins with poly(carboxylic acids).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204274"} {"pmid": "4204276", "title": "Heterogeneity of lobster agglutinins. II. Specificity of agglutinin-erythrocyte binding.", "content": "Heterogeneity of lobster agglutinins. II. Specificity of agglutinin-erythrocyte binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204276"} {"pmid": "4204275", "title": "Heterogeneity of lobster agglutinins. I. Purification and physiochemical characterization.", "content": "Heterogeneity of lobster agglutinins. I. Purification and physiochemical characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204275"} {"pmid": "4204291", "title": "Effects of halothane on left ventricular function and distribution of regional blood flow in dogs and primates.", "content": "Effects of halothane on left ventricular function and distribution of regional blood flow in dogs and primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204291"} {"pmid": "4204295", "title": "Influence of membrane lipids on the regulatory properties of UDP-glucuronyltransferase.", "content": "Influence of membrane lipids on the regulatory properties of UDP-glucuronyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204295"} {"pmid": "4204294", "title": "Crystalline kidney-bean leucoagglutinin.", "content": "Crystalline kidney-bean leucoagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204294"} {"pmid": "4204296", "title": "Electroejaculation technique in Macaca mulatta (rhesus monkeys).", "content": "Electroejaculation technique in Macaca mulatta (rhesus monkeys).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204296"} {"pmid": "4204298", "title": "The use of sensitized latex in the identification of human bloodstains.", "content": "The use of sensitized latex in the identification of human bloodstains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204298"} {"pmid": "4204299", "title": "Iodination (125I) of the apical plasma membrane of toad bladder epithelium: electron-microscopic autoradiography and physiological effects.", "content": "Iodination (125I) of the apical plasma membrane of toad bladder epithelium: electron-microscopic autoradiography and physiological effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204299"} {"pmid": "4204300", "title": "Varieties of hypothyroidism.", "content": "Varieties of hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204300"} {"pmid": "4204293", "title": "Effect of Na salts of organic acids on acid induced swelling and K loss in Pseudomonas aeruginosa and effect of pH on actions of mercuric, cadmium and zinc salts.", "content": "Effect of Na salts of organic acids on acid induced swelling and K loss in Pseudomonas aeruginosa and effect of pH on actions of mercuric, cadmium and zinc salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204293"} {"pmid": "4204305", "title": "Psychological aspects of sudden unexpected death in infants and children.", "content": "Psychological aspects of sudden unexpected death in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204305"} {"pmid": "4204309", "title": "Prostaglandin mediated inhibition of noradrenaline release at different nerve impulse frequencies.", "content": "Prostaglandin mediated inhibition of noradrenaline release at different nerve impulse frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204309"} {"pmid": "4204310", "title": "Electrophysiological study of the gustatory effects of the sweet proteins monellin and thaumatin in monkey, guinea pig and rat.", "content": "Electrophysiological study of the gustatory effects of the sweet proteins monellin and thaumatin in monkey, guinea pig and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204310"} {"pmid": "4204311", "title": "Funduscopic alterations in the rhesus monkey induced by exposure to heavy ions (O+8) 250 MeV nucleon.", "content": "Funduscopic alterations in the rhesus monkey induced by exposure to heavy ions (O+8) 250 MeV nucleon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204311"} {"pmid": "4204302", "title": "A comparative study of precipiting serological techniques for the detection of meningococcal polysaccharide.", "content": "A comparative study of precipiting serological techniques for the detection of meningococcal polysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204302"} {"pmid": "4204303", "title": "Metabolic inhibition test for the measurement of antibody to Neisseria meningitidis.", "content": "Metabolic inhibition test for the measurement of antibody to Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204303"} {"pmid": "4204313", "title": "Congenital gastric diverticulum as a cause of massive hemorrhage.", "content": "Congenital gastric diverticulum as a cause of massive hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204313"} {"pmid": "4204312", "title": "Increased jejunal IgA synthesis in vitro during acute infectious nonbacterial gastroenteritis.", "content": "Increased jejunal IgA synthesis in vitro during acute infectious nonbacterial gastroenteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204312"} {"pmid": "4204314", "title": "An epidemiologic survey of arterial blood pressure in a large male population group.", "content": "An epidemiologic survey of arterial blood pressure in a large male population group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204314"} {"pmid": "4204315", "title": "Hepatitis and hepatitis B-antigen in Greenland.", "content": "Hepatitis and hepatitis B-antigen in Greenland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204315"} {"pmid": "4204308", "title": "On findings of virus-like structures in uterine cervical carcinoma.", "content": "On findings of virus-like structures in uterine cervical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204308"} {"pmid": "4204316", "title": "Inhibition of in vivo and in vitro epoxidation of aldrin, and potentiation of toxicity of various insecticide chemicals by diquat in two species of fish.", "content": "Inhibition of in vivo and in vitro epoxidation of aldrin, and potentiation of toxicity of various insecticide chemicals by diquat in two species of fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204316"} {"pmid": "4204317", "title": "Polychlorinated biphenyls (PCBs) as inducers of microsomal enzyme activity in the house fly.", "content": "Polychlorinated biphenyls (PCBs) as inducers of microsomal enzyme activity in the house fly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204317"} {"pmid": "4204319", "title": "Precipitating antibodies for an avian adenovirus in Queensland poultry flocks.", "content": "Precipitating antibodies for an avian adenovirus in Queensland poultry flocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204319"} {"pmid": "4204320", "title": "Letter: Very small public health risk from flesh of tuberculous cattle.", "content": "Letter: Very small public health risk from flesh of tuberculous cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204320"} {"pmid": "4204318", "title": "The central nervous system pharmacology of an anti-emetic dihydroindolone derivative.", "content": "The central nervous system pharmacology of an anti-emetic dihydroindolone derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204318"} {"pmid": "4204321", "title": "Identification and measurement of the folates in sheep liver.", "content": "Identification and measurement of the folates in sheep liver. 1. Methods are described for the extraction, separation by ion-exchange chromatography and estimation by microbiological assay of the folates in sheep liver. 2. Injection of [2-(14)C]-pteroylglutamate into a sheep fed on a stock diet led to extensive labelling of chromatographically separable liver folates. About 12% of the label in the liver could not be extracted by the method used. 3. Liver folates were examined in five ewes fed on restricted amounts of a diet of wheaten hay-chaff and gluten and injected weekly with vitamin B(12). Chromatographic separation was followed by microbiological assay with Lactobacillus casei, Streptococcus faecalis R. and Pediococcus cerevisiae both before and after treatment of fractions with conjugase (gamma-glutamylcarboxypeptidase). Evidence was obtained that the folates present were predominantly polyglutamate forms of tetrahydropteroylglutamate, 5-methyltetrahydropteroylglutamate and 5- (and 10-) formyltetrahydropteroylglutamates. Differences in the responses of the assay organisms permitted quantitative distinction between these three main classes of folates. 4. Methyltetrahydrofolates were eluted in seven successive peaks that were separated by constant increments in the logarithm of eluant [P(i)]. A similar relationship existed for seven successive peaks of tetrahydrofolate and may also have existed for each of the two series of formyltetrahydrofolates. 5. Based on these and other observations it is proposed that sheep liver folates consist predominantly of the mono- to hepta-glutamates of each of the reduced pteroates identified. The methods employed allowed quantitative determinations to be made of most of the folates present. The predominant forms were hexaglutamates. 6. Four components active for L. casei were detected that could not be identified. Three of them were polyglutamates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204321"} {"pmid": "4204323", "title": "The role of multivalent cations in the uptake and oxidation of glucose by Pseudomonas fluorescens.", "content": "The role of multivalent cations in the uptake and oxidation of glucose by Pseudomonas fluorescens. The effects of Mg(2+), Mn(2+), Ca(2+) and Fe(3+) on the uptake and oxidation of glucose in induced and non-induced Pseudomonas fluorescens cells were studied. Mg(2+) is the most effective single metal ion in the uptake of glucose by the cell, and it functions in membrane stabilization and enzymic activity. Ca(2+) will substitute for Mg(2+), but Mn(2+) and Fe(3+) will not.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204323"} {"pmid": "4204322", "title": "Folic acid metabolism in vitamin B12-deficient sheep. Depletion of liver folates.", "content": "Folic acid metabolism in vitamin B12-deficient sheep. Depletion of liver folates. 1. Metabolism of folate was studied in six ewes in an advanced state of vitamin B(12) deficiency as judged by voluntary food intake and in their pair-fed controls receiving vitamin B(12). A group of four animals that were maintained throughout the experiment at pasture was also studied. 2. After 34-40 weeks on the cobalt-deficient diet urinary excretion of formiminoglutamate by four deficient animals was about 3.2mmol/day and this was not significantly decreased by injection of three of them with about 4.5mug of [2-(14)C]folate/kg body weight per day for 5 days. Three days after the last injection retention of [2-(14)C]folate by the livers of the deficient animals (5.5% of the dose) was lower than that of their pair-fed controls (26% of the dose) but there was no evidence of net retention of injected folate in the livers of either group. Urinary excretion of (14)C indicated that renal clearance of folate may have been impaired in very severe vitamin B(12) deficiency. 3. As estimated by microbiological assays total folates in the livers of animals at pasture (12.9mug/g) included about 24% of 5-methyltetrahydrofolate as compared with about 72% of a total of 12.5mug/g in three further ewes fed on a stock diet of wheaten hay-chaff and lucerne-chaff. Liver folates of vitamin B(12)-deficient animals (0.5mug/g) included about 88% of 5-methyltetrahydrofolate as compared with about 51% of a total of 5.2mug/g in pair-fed animals treated with vitamin B(12). 4. Chromatography of liver folates of the pair-fed animals permitted quantitative estimates of the pteroylglutamates present. The results showed that the vitamin B(12)-deficient livers were more severely depleted of tetrahydrofolates and formyltetrahydrofolates than of methyltetrahydrofolates and that as the deficiency developed they were more severely depleted of the higher polyglutamates than of the monoglutamate within each of these classes. Results from animals injected with [2-(14)C]folate indicated an impairment of the exchange between pteroylmonoglutamates and pteroylpolyglutamates in the livers of deficient animals. 5. In vitamin B(12)-deficient animals with food intakes below 200g/day some of the liver folates were not completely reduced and some degradation of pteroylpolyglutamates was detected. The latter condition may have been associated with fatty liver. 6. The results are discussed in relation to current theories of vitamin B(12)-folate interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204322"} {"pmid": "4204326", "title": "Effects of colchicine and 2-Br-alpha-ergocryptine-methane-sulfonate (CB 154) on the release of prolactin and growth hormone by functional pituitary tumor cells in culture.", "content": "Effects of colchicine and 2-Br-alpha-ergocryptine-methane-sulfonate (CB 154) on the release of prolactin and growth hormone by functional pituitary tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204326"} {"pmid": "4204327", "title": "Inactivation of protein synthesis stimulating activity in serum by cells.", "content": "Inactivation of protein synthesis stimulating activity in serum by cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204327"} {"pmid": "4204328", "title": "Factors affecting pH-dependent photo-inhibition of division in Euglena gracilis.", "content": "Factors affecting pH-dependent photo-inhibition of division in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204328"} {"pmid": "4204329", "title": "The toxic effects of phenoloxidase from the haemolymph of tenebrionid beetles.", "content": "The toxic effects of phenoloxidase from the haemolymph of tenebrionid beetles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204329"} {"pmid": "4204330", "title": "The effect of eye colour pigments on the action spectrum of Drosophila.", "content": "The effect of eye colour pigments on the action spectrum of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204330"} {"pmid": "4204332", "title": "Alpha-glycerophosphate dehydrogenase in Drosophila melanogaster: kinetic differences and developmental differentiation of the larval and adult isozymes.", "content": "Alpha-glycerophosphate dehydrogenase in Drosophila melanogaster: kinetic differences and developmental differentiation of the larval and adult isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204332"} {"pmid": "4204336", "title": "Synthesis of pyrimido(4,5-b)(1,4)-7-hydrothiazines related to 7,8-dihydropteridines of biological importance.", "content": "Synthesis of pyrimido(4,5-b)(1,4)-7-hydrothiazines related to 7,8-dihydropteridines of biological importance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204336"} {"pmid": "4204335", "title": "6-Phenyl-4,5-dihydro-3(2H)-pyridazinones. A series of hypotensive agents.", "content": "6-Phenyl-4,5-dihydro-3(2H)-pyridazinones. A series of hypotensive agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204335"} {"pmid": "4204338", "title": "Agenesis of the corpus callosum in two sisters.", "content": "Agenesis of the corpus callosum in two sisters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204338"} {"pmid": "4204337", "title": "Thanatophoric dwarfism.", "content": "Thanatophoric dwarfism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204337"} {"pmid": "4204339", "title": "Trisomy 13 in two infants with cyclops.", "content": "Trisomy 13 in two infants with cyclops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204339"} {"pmid": "4204340", "title": "The effect of tanning agents on the permeability of the toad bladder to water and solutes.", "content": "The effect of tanning agents on the permeability of the toad bladder to water and solutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204340"} {"pmid": "4204342", "title": "Studies in the pathogenesis, diagnosis, and treatment of Candida sepsis in children.", "content": "Studies in the pathogenesis, diagnosis, and treatment of Candida sepsis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204342"} {"pmid": "4204343", "title": "Synthesis and antimicrobial properties of 17beta-amino-4-aza-5alpha-androstane and derivatives.", "content": "Synthesis and antimicrobial properties of 17beta-amino-4-aza-5alpha-androstane and derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204343"} {"pmid": "4204341", "title": "Innervation of abdominal paraganglia: an ultrastructural study.", "content": "Innervation of abdominal paraganglia: an ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204341"} {"pmid": "4204345", "title": "Electrokinetic studies of bacteria. IV. Effect of acridines on Streptococcus faecalis.", "content": "Electrokinetic studies of bacteria. IV. Effect of acridines on Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204345"} {"pmid": "4204344", "title": "Structure relationship for binding of sulfonamides and penicillins to bovine serum albumin by fluorescence probe technique.", "content": "Structure relationship for binding of sulfonamides and penicillins to bovine serum albumin by fluorescence probe technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204344"} {"pmid": "4204346", "title": "Pharmacokinetics of pentazocine in the rhesus monkey.", "content": "Pharmacokinetics of pentazocine in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204346"} {"pmid": "4204347", "title": "Drug absorption in rats pretreated with antibiotics.", "content": "Drug absorption in rats pretreated with antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204347"} {"pmid": "4204348", "title": "Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).", "content": "Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204348"} {"pmid": "4204349", "title": "Alterations by neomycin of 45Ca movements and contractile responses in vascular smooth muscle.", "content": "Alterations by neomycin of 45Ca movements and contractile responses in vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204349"} {"pmid": "4204356", "title": "Intragenic somatic recombination in the lozenge cistron of Drosophila.", "content": "Intragenic somatic recombination in the lozenge cistron of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204356"} {"pmid": "4204357", "title": "Biochemical genetics of bacterial sporulation. IV. Sequential development of resistances to chemical and physical agents during sporulation of Bacillus subtilis.", "content": "Biochemical genetics of bacterial sporulation. IV. Sequential development of resistances to chemical and physical agents during sporulation of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204357"} {"pmid": "4204360", "title": "The use of hyperalimentation in patients with potential sepsis.", "content": "The use of hyperalimentation in patients with potential sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204360"} {"pmid": "4204361", "title": "Xenogeneic renal preservation for transplantation in primates. II. Rejection of stored allografts.", "content": "Xenogeneic renal preservation for transplantation in primates. II. Rejection of stored allografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204361"} {"pmid": "4204362", "title": "Separation of the immunosuppressive and glomerular basement membrane-reactive antibodies in horse antiserum to human thymus.", "content": "Separation of the immunosuppressive and glomerular basement membrane-reactive antibodies in horse antiserum to human thymus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204362"} {"pmid": "4204363", "title": "Rabbit antisera to HL-A9 isolated from normal serum.", "content": "Rabbit antisera to HL-A9 isolated from normal serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204363"} {"pmid": "4204358", "title": "The effect of sympathetic denervation on cerebral CO2 sensitivity.", "content": "The effect of sympathetic denervation on cerebral CO2 sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204358"} {"pmid": "4204359", "title": "Stroke surveillance: the concept of stroke team in diagnosis, treatment and prevention.", "content": "Stroke surveillance: the concept of stroke team in diagnosis, treatment and prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204359"} {"pmid": "4204374", "title": "Behavioural changes in primates and diazepam metabolism.", "content": "Behavioural changes in primates and diazepam metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204374"} {"pmid": "4204376", "title": "The microbiology of burukutu beer.", "content": "The microbiology of burukutu beer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204376"} {"pmid": "4204381", "title": "Neurofibromatosis of the pelvis and bladder. Case report and review of the literature.", "content": "Neurofibromatosis of the pelvis and bladder. Case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204381"} {"pmid": "4204379", "title": "Interspecies variations in small intestinal and hepatic drug hydroxylation and glucuronidation.", "content": "Interspecies variations in small intestinal and hepatic drug hydroxylation and glucuronidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204379"} {"pmid": "4204380", "title": "Thyroid function and dysfunction during pregnancy.", "content": "Thyroid function and dysfunction during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204380"} {"pmid": "4204384", "title": "A comparison of in vivo and in vitro microleakage of dental restorations.", "content": "A comparison of in vivo and in vitro microleakage of dental restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204384"} {"pmid": "4204385", "title": "Spontaneous perforation of a jejunal diverticulum.", "content": "Spontaneous perforation of a jejunal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204385"} {"pmid": "4204386", "title": "A 'new' saliva substance, probably inherited, and serologically independent of ABH, Lewis, and Sda blood group substances.", "content": "A 'new' saliva substance, probably inherited, and serologically independent of ABH, Lewis, and Sda blood group substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204386"} {"pmid": "4204387", "title": "Genetic association in myocardial infarction. Ethnicity; ABO, Rh, Le, Xg blood groups; G6PD deficiency; and abnormal haemoglobins.", "content": "Genetic association in myocardial infarction. Ethnicity; ABO, Rh, Le, Xg blood groups; G6PD deficiency; and abnormal haemoglobins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204387"} {"pmid": "4204388", "title": "Health in the midst of economic development in Taiwan.", "content": "Health in the midst of economic development in Taiwan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204388"} {"pmid": "4204392", "title": "A positive approach to being negative.", "content": "A positive approach to being negative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204392"} {"pmid": "4204397", "title": "A controlled comparison of two fully supervised once-weekly regimens in the treatment of newly diagnosed pulmonary tuberculosis.", "content": "A controlled comparison of two fully supervised once-weekly regimens in the treatment of newly diagnosed pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204397"} {"pmid": "4204398", "title": "The differential tuberculin test in tuberculosis patients.", "content": "The differential tuberculin test in tuberculosis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204398"} {"pmid": "4204389", "title": "Effect of iron deprivation and temperature upon bacterial survival.", "content": "Effect of iron deprivation and temperature upon bacterial survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204389"} {"pmid": "4204399", "title": "Tuberculosis in a patient after renal transplantation.", "content": "Tuberculosis in a patient after renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204399"} {"pmid": "4204390", "title": "Particulate nature of o-diphenoloxidase in Mycobacterium leprae and assay of the enzyme by the radioisotope technique.", "content": "Particulate nature of o-diphenoloxidase in Mycobacterium leprae and assay of the enzyme by the radioisotope technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204390"} {"pmid": "4204401", "title": "The fine structure of intracerebral vessels.", "content": "The fine structure of intracerebral vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204401"} {"pmid": "4204402", "title": "Studies on the interaction between staphylococcal protein a and the fc-region of immunoglobulin G.", "content": "Studies on the interaction between staphylococcal protein a and the fc-region of immunoglobulin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204402"} {"pmid": "4204403", "title": "Immunoglobulins in eluates of malignant human tumours.", "content": "Immunoglobulins in eluates of malignant human tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204403"} {"pmid": "4204396", "title": "Ocular coccidioidomycosis. A clinicopathologic case report.", "content": "Ocular coccidioidomycosis. A clinicopathologic case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204396"} {"pmid": "4204406", "title": "Alpha1-fetoprotein and liver-specific antigen in viral hepatitis type B.", "content": "Alpha1-fetoprotein and liver-specific antigen in viral hepatitis type B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204406"} {"pmid": "4204410", "title": "Sex differences, environmental complexity, and mother-infant relations.", "content": "Sex differences, environmental complexity, and mother-infant relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204410"} {"pmid": "4204411", "title": "Differential effects of amygdalectomy in male and female nonhuman primates.", "content": "Differential effects of amygdalectomy in male and female nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204411"} {"pmid": "4204412", "title": "Contrasting adult male roles in different species of nonhuman primates.", "content": "Contrasting adult male roles in different species of nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204412"} {"pmid": "4204413", "title": "Male-female residence arrangements and political power in human hunter-gatherers.", "content": "Male-female residence arrangements and political power in human hunter-gatherers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204413"} {"pmid": "4204414", "title": "Male-female, female-female, and male-male sexual behavior in the stumptail monkey, with special attention to the female orgasm.", "content": "Male-female, female-female, and male-male sexual behavior in the stumptail monkey, with special attention to the female orgasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204414"} {"pmid": "4204415", "title": "The effect of blood on disinfection of surgeons' hands.", "content": "The effect of blood on disinfection of surgeons' hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204415"} {"pmid": "4204416", "title": "Quantitation of C3PA (properdin factor B) and other complement components in diseases associated with a low C3 level.", "content": "Quantitation of C3PA (properdin factor B) and other complement components in diseases associated with a low C3 level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204416"} {"pmid": "4204417", "title": "Heavy chain subclass of human anti-platelet antibodies.", "content": "Heavy chain subclass of human anti-platelet antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204417"} {"pmid": "4204418", "title": "Breakdown of noncollagenous chondromucoprotein matrix by leukocyte lysosome granule lysates from guinea pig, rabbit, and human.", "content": "Breakdown of noncollagenous chondromucoprotein matrix by leukocyte lysosome granule lysates from guinea pig, rabbit, and human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204418"} {"pmid": "4204419", "title": "Increased bactericidal activity by non-specific stimulation of lymphoid cells--experiments in vivo with concanavalin A.", "content": "Increased bactericidal activity by non-specific stimulation of lymphoid cells--experiments in vivo with concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204419"} {"pmid": "4204420", "title": "The early immune response to Mycobacterium lepraemurium in inbred mice and rats.", "content": "The early immune response to Mycobacterium lepraemurium in inbred mice and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204420"} {"pmid": "4204421", "title": "Incidence of nuclear antibodies in patients and in related and unrelated groups from a community with a \"microepidemic\" of systemic lupus erythematosus.", "content": "Incidence of nuclear antibodies in patients and in related and unrelated groups from a community with a \"microepidemic\" of systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204421"} {"pmid": "4204422", "title": "Insulinotrophic drugs. Effect on intestinal abosorption of sugar.", "content": "Insulinotrophic drugs. Effect on intestinal abosorption of sugar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204422"} {"pmid": "4204423", "title": "Insulin degradation. VI. Feedback control by insulin of liver glutathione-insulin transhydrogenase in rat.", "content": "Insulin degradation. VI. Feedback control by insulin of liver glutathione-insulin transhydrogenase in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204423"} {"pmid": "4204424", "title": "Serum enzyme changes in diabetic ketoacidosis.", "content": "Serum enzyme changes in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204424"} {"pmid": "4204425", "title": "Two forms of the DNA ligase of human cells.", "content": "Two forms of the DNA ligase of human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204425"} {"pmid": "4204431", "title": "Neuroendocrine relationships in farm animals: a review.", "content": "Neuroendocrine relationships in farm animals: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204431"} {"pmid": "4204426", "title": "[The growth of avian coccidia in the developing chick embryo and in cultured cells (author's transl)].", "content": "[The growth of avian coccidia in the developing chick embryo and in cultured cells (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204426"} {"pmid": "4204432", "title": "Control of deoxyribonucleic acid synthesis in a Bacillus subtilis mutant temperature sensitive for initiation of chromosome replication.", "content": "Control of deoxyribonucleic acid synthesis in a Bacillus subtilis mutant temperature sensitive for initiation of chromosome replication. We used a Bacillus subtilis mutant described previously, which is temperature sensitive for initiation of replication. The inhibition of deoxyribonucleic acid synthesis occurring at 45 C was shown to be reversed when the temperature is lowered even in the absence of protein synthesis. If the bacteria are returned to 30 C, after a prior period at 45 C, they are able to initiate the first round of replication in the presence of chloramphenicol, but the initiation of the second round still requires protein synthesis. This paper shows that the proteins necessary to initiate the second round of replication can be present in bacteria long before this round is initiated. In addition, the appearance of these proteins seems to be influenced by the length of the previous 45 C period. Although similar reinitiation kinetics are observed at 30 C after prior 45 C periods of 30 or 65 min, the ability to initiate the second round without further protein synthesis appears much earlier after a longer exposure at 45 C. To explain these results, a hypothesis is presented which assumes that two different proteins are both necessary for initiation. Only one of these proteins could be accumulated at 45 C during the inhibition of deoxyribonucleic acid synthesis. A peculiarity of initiation material in mutant Ts 37 is that it may be active at 45 C if it has been exposed previously at 30 C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204432"} {"pmid": "4204434", "title": "C4-dicarboxylate transport in Bacillus subtilis studied with 3-fluoro-L-erythro-malate as a substrate.", "content": "C4-dicarboxylate transport in Bacillus subtilis studied with 3-fluoro-L-erythro-malate as a substrate. Bacillus subtilis cells grown in yeast extract medium accumulated 3-fluoro-l-erythro-[1,2-(14)C(2)]malate more than 30-fold from the surrounding medium. No metabolic products derived from 3-fluoro-l-erythro-malate could be detected in these cells. l-Malate competitively inhibited transport of 3-fluoro-l-erythro-malate. This malate analogue was itself a competitive inhibitor of l-malate uptake. Cells that had been grown in yeast extract supplemented with 5 mM l-malate showed a 10-fold increased affinity towards 3-fluoro-l-erythro-malate relative to cells grown in yeast extract medium with no added malate. Our results suggest that two transport systems for l-malate can be induced in B. subtilis. The first of these systems seems to effect uptake of C(4)-dicarboxylates (l-malate, succinate, and fumarate) in yeast extract medium. The second transport system (or possibly a modification of the first transport system) seems to be induced by addition of l-malate to this medium and is also functioning in malate minimal medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204434"} {"pmid": "4204433", "title": "Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes.", "content": "Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. A strain of Streptococcus faecalis var. zymogenes, designated JH1, had high-level resistance to the antibiotics streptomycin, kanamycin, neomycin, erythromycin, and tetracycline. These resistances were lost en bloc from approximately 0.1% of cells grown in nutrient broth at 45 C. The frequency of resistance loss was not increased by growth in the presence of the \"curing\" agents acriflavine or acridine orange, but after prolonged storage in nutrient agar 17% of cells became antibiotic sensitive. Covalently closed circular deoxyribonucleic acid (DNA) molecules were isolated from the parental strain and from antibiotic-sensitive segregants by using cesium chloride-ethidium bromide gradients. DNA molecular species were identified by using neutral sucrose gradients. Strain JH1 contained two covalently closed circular DNA species of molecular weights 50 x 10(6) and 38 x 10(6). An antibiotic-sensitive segregant, strain JH1-9, had lost the larger molecular species. A second sensitive segregant, strain JH1-5, had also lost the larger molecular species but a new molecular species of approximate molecular weight 6 x 10(6) was present. The antibiotic resistances that were curable from the parental strain were transferred to antibiotic-sensitive strains of S. faecalis and to strain JH1-9, during mixed incubation in nutrient broth at 37 C. Data to be described are interpreted to suggest that the transfer is by a conjugal mechanism. Analysis of the plasmid species in recipient clones showed that all had received the plasmid of molecular weight 50 x 10(6). Strain JH1-5 was not a good recipient. Analysis of one successful recipient clone of JH1-5 revealed that it had gained the 50 x 10(6) molecular weight plasmid but lost the 6 x 10(6) molecular weight species. These data are interpreted to mean that the multiple antibiotic resistance is borne by a transferable plasmid of 50 x 10(6) molecular weight, and that in clone JH1-5 this plasmid suffered a large deletion leaving only a 6 x 10(6) remnant which was incompatible with the complete replicon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204433"} {"pmid": "4204435", "title": "L-amino acid dehydrogenases in Bacillus subtilis spores.", "content": "L-amino acid dehydrogenases in Bacillus subtilis spores. The presence of two kinds of l-amino acid dehydrogenase in resting spores of Bacillus subtilis was indicated. One of them was l-alanine dehydrogenase, which used only l-alanine as a substrate, and the other was nonspecific dehydrogenase, which used l-valine, l-isoleucine, l-leucine, and l-alanine (slightly) as substrates. Several properties of these dehydrogenases were compared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204435"} {"pmid": "4204430", "title": "Screening for alpha 1-antitrypsin deficiency.", "content": "Screening for alpha 1-antitrypsin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204430"} {"pmid": "4204436", "title": "Buoyant density heterogeneity in spores of Bacillus subtilis: biochemical and physiological basis.", "content": "Buoyant density heterogeneity in spores of Bacillus subtilis: biochemical and physiological basis. The biochemical and physiological basis of density heterogeneity in Renografin of Bacillus subtilis W23 spores was determined by analysis of metals, macromolecules, and dipicolinic acid in the two density classes of the population. Germination rate and heat resistance were measured in both density classes. Atomic absorption spectrophotometry revealed that heavy spores (density = 1.335 g/ml) have 30% more calcium than light spores (density = 1.290 g/ml). Other metals found in greater amounts in heavy spores were manganese and potassium. However, light spores had more sodium than heavy spores. The amounts of carbohydrates, nucleic acids, and proteins were the same in both types of spores, but light spores contained more lipids, whereas heavy spores had 30% more dipicolinic acid than light spores. Calcium and lipid were excluded as causes of the heterogeneity in density in that alteration of their contents in spores did not detectably affect the density of these spores. Spores of two densities were genetically similar. Furthermore, light density spores arose earlier during sporulation than heavy spores as determined by releasing refractile forespores at various times during sporulation. We concluded that light spores represent an incomplete stage in development because they became heavy when reinoculated into spent sporulation medium. This must involve the additional accretion or synthesis of dipicolinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204436"} {"pmid": "4204437", "title": "Precursor of 5S ribosomal ribonucleic acid in the blue-green alga Anacystis nidulans.", "content": "Precursor of 5S ribosomal ribonucleic acid in the blue-green alga Anacystis nidulans. The maturation of 5S ribosomal ribonucleic acid (rRNA) in the obligately photoautotrophic unicellular blue-green alga Anacystis nidulans has been studied by using polyacrylamide gel electrophoresis and T1 ribonuclease oligonucleotide analysis. A. nidulans mature 5S rRNA (m5) is of approximately the same molecular weight as the 5S rRNA of Escherichia coli, and is derived by cleavage of a precursor (p5) containing a few (three to six) additional nucleotides. Some of these additional nucleotides occur at the 5' end of the precursor molecule; others may occur at the 3' end. Kinetic experiments indicate that precursors of mature 5S rRNA larger than p5 either do not exist or are very transient in A. nidulans. These results are discussed in relation to those obtained with other prokaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204437"} {"pmid": "4204439", "title": "Effect of viscosity on bacterial motility.", "content": "Effect of viscosity on bacterial motility. The behavior of a number of motile flagellated bacteria toward viscosity characteristics of their fluid environments was observed. All showed an increase in velocity (micrometers per second) in more viscous solutions. Velocity reached a maximum at a characteristic value, however, and thereafter decreased with higher viscosities. Peritrichously flagellated bacteria had maximum velocities at higher viscosities than polarly flagellated bacteria. Effects of temperature, and possible utilization of chemical constituents in the viscous solutions, were studied and found to be negligible factors under the experimental conditions used. Different agents produced the same phenomenon, thus indicating that there probably were no chemically induced metabolic effects. Loss of available water and the possibility of a variable energy supply to the flagellar propulsive system were considered but are believed minimal. Theoretically derived thermodynamic equations were utilized and suggest that the conformation of the flagellar helix affects efficiency of propulsion. Such a relationship between helix waveform and velocity was experimentally observed with Thiospirillum jenese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204439"} {"pmid": "4204438", "title": "Beta-D-phosphogalactoside galactohydrolase from Streptococcus cremoris HP: purification and enzyme properties.", "content": "Beta-D-phosphogalactoside galactohydrolase from Streptococcus cremoris HP: purification and enzyme properties. beta-d-phosphogalactoside galactohydrolase (beta-PGal) was isolated and purified from cell-free extracts of Streptococcus cremoris HP to apparent homogeneity to gel electrophoresis. Using the chromogenic o-nitrophenol-beta-d-galactopyranoside-6-phosphate as substrate, the purified enzyme exhibited a specific activity of 18.71 U/mg of protein and K(m) and V(max) values of 5.88 x 10(-4) M and 23.8 mumol of o-nitrophenol liberated per min per mg of protein, respectively. d-Galactose-6-phosphate was a weak competitive inhibitor of beta-PGal. Activity was relatively heat resistant and was maximal from pH 5.0 to 8.0 and over a temperature range of 45 to 52 C. Dithiothreitol, ethylenediaminetetraacetic acid, and citrate stimulated beta-PGal activity, whereas Mg(2+), Li(1+), and p-hydroxymercuribenzoate were inhibitory. Molecular weight of the enzyme was estimated at 6.76 x 10(4). Amino acid composition was similar to other beta-phosphogalactosidases previously investigated, with the exception that the S. cremoris enzyme contains a small amount of half cystine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204438"} {"pmid": "4204440", "title": "Transcription from the complementary deoxyribonucleic acid strands of Bacillus subtilis during various stages of sporulation.", "content": "Transcription from the complementary deoxyribonucleic acid strands of Bacillus subtilis during various stages of sporulation. The messenger ribonucleic acid (mRNA) pattern of log-phase and sporulating cells of Bacillus subtilis has been analyzed by deoxyribonucleic acid (DNA)-RNA hybrid studies with the complementary-strand fragments of DNA. Approximately 80% of the mRNA of log-phase and sporulating cells from stages I, III, and IV hybridizes with the heavy DNA fragments, and 20% hybridizes with the light DNA fragments. Hybrid competition studies indicated that there was either a greatly reduced rate of transcription or a turn-off of some log-phase genes during the sporulation stages. However, a significant amount of log-phase gene transcription occurred even at late stages of sporulation. Similar studies indicate a significantly increased rate of transcription or a turn-on of sporulation phase genes during the latter stages of sproulation. There is a sequential increase in the amount of sporulation-specific transcription from both complementary-strand fragments of DNA. These results indicate that the RNA polymerase population in sporulating cells can transcribe both log-phase and sporulation-phase genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204440"} {"pmid": "4204441", "title": "Inhibition of the Bacillus subtilis membrane-bound D-alanine carboxypeptidase by 6-aminopenicillanic acid covalently coupled to sepharose.", "content": "Inhibition of the Bacillus subtilis membrane-bound D-alanine carboxypeptidase by 6-aminopenicillanic acid covalently coupled to sepharose. An insoluble penicillin derivative, 6-aminopenicillanic acid covalently coupled to Sepharose, was used to investigate the location of the d-alanine carboxypeptidase in the Bacillus subtilis membrane. Only 50% of the enzymatic activity in protoplasts and 74% of that in purified membranes was sensitive, although the purified enzyme could be inhibited completely by the resin. These results suggest that a minimum of 50% of the d-alanine carboxypeptidase exists on the outer face of the bacterial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204441"} {"pmid": "4204442", "title": "Degradative effect of phenol on endotoxin and lipopolysaccharide preparations from Serratia marcescens.", "content": "Degradative effect of phenol on endotoxin and lipopolysaccharide preparations from Serratia marcescens. It has been established that the well-known deproteinizing action of hot 45% aqueous phenol on whole cells or isolated and purified endotoxin of Serratia marcescens 08 is caused by the cleavage of a phenol-sensitive linkage within the lipid moiety. As a result of this degradation, both the lipopolysaccharide and simple protein fragments retained a part of the lipid moiety. Although not proceeding at the same fast rate as the cleavage of the lipid moiety, such phenol treatment also caused a partial hydrolysis of the O-specific side chain and ester-bound fatty acids. Hydrolysis of the O-specific side chain accounted for 5% of the lipopolysaccharide and that of ester-bound fatty acids accounted for 11% of the total fatty acid content after 60 min of treatment. It is suggested that the presence of these degradation products is one of the main causes of the heterogeneity of endotoxin and lipopolysaccharide preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204442"} {"pmid": "4204443", "title": "Phycobilisomes in blue-green algae.", "content": "Phycobilisomes in blue-green algae. Fifteen species of freshwater blue-green algae, including unicellular, filamentous, and colonial forms, were subjected to a variety of fixatives, fixation conditions, and stains for comparison of the preservation of phycobilisomes. Absorption spectra of the corresponding in vivo and released photosynthetic pigments, in 10 of the species that were maintained in culture, demonstrated the presence of phycocyanin in all 10 species and phycoerythrin in only 2 of them. Spectroscope and electron microscope evidence was obtained for localization of phycobiliproteins in phycobilisomes of Nostoc muscorum. Phycobilisomes were observed in all species examined in situ, strenghening the hypothesis that phycobilisomes are common to all phycobiliprotein-containing photosynthetic blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204443"} {"pmid": "4204444", "title": "Mutant of Bacillus subtilis lacking exo-beta-N-acetylglucosaminidase activity.", "content": "Mutant of Bacillus subtilis lacking exo-beta-N-acetylglucosaminidase activity. A procedure for the isolation of exo-beta-N-acetylglucosaminidase mutants, by using a plate assay method incorporating a fluorescent substrate, has been developed. A mutant lacking exo-beta-N-acetylglucosaminidase activity has been isolated and shown to grow, divide, autolyze, and sporulate as well as the parental strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204444"} {"pmid": "4204445", "title": "Mutant of Azotobacter vinelandii that hyperproduces nitrogenase component II.", "content": "Mutant of Azotobacter vinelandii that hyperproduces nitrogenase component II. A mutant strain of Azotobacter vinelandii that is unable to fix N(2) produces high levels of nitrogenase component II. Activities of revertants from this mutant strain indicate that a single genetic lesion is responsible for both hyperproduction of component II and the inability to produce component I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204445"} {"pmid": "4204446", "title": "Penicillin binding components in Bacillus subtilis during sporulation.", "content": "Penicillin binding components in Bacillus subtilis during sporulation. The penicillin binding components of sporulating Bacillus subtilis 3610 were compared with those of the vegetative organism. No qualitative difference in binding components was observed. The total binding, however, varied with the phase of sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204446"} {"pmid": "4204447", "title": "D-alanine carboxypeptidase and cell wall cross-linking in Bacillus subtilis.", "content": "D-alanine carboxypeptidase and cell wall cross-linking in Bacillus subtilis. Inhibition of d-alanine carboxypeptidase in Bacillus subtilis by 95% caused no measurable change in the degree of cross-linking of the peptidoglycan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204447"} {"pmid": "4204448", "title": "Maturation of spatial delayed responses to auditory cues in kittens.", "content": "Maturation of spatial delayed responses to auditory cues in kittens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204448"} {"pmid": "4204449", "title": "Studies of cell-mediated immunity and allergy in protein energy malnutrition. I. Cell-mediated delayed hypersensitivity.", "content": "Studies of cell-mediated immunity and allergy in protein energy malnutrition. I. Cell-mediated delayed hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204449"} {"pmid": "4204450", "title": "Studies of cell-mediated immunity and allergy in protein energy malnutrition. II. Immediate hypersensitivity.", "content": "Studies of cell-mediated immunity and allergy in protein energy malnutrition. II. Immediate hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204450"} {"pmid": "4204477", "title": "Effect of some factors on the biological activity of measles virus.", "content": "Effect of some factors on the biological activity of measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204477"} {"pmid": "4204479", "title": "Polychlorinated biphenyls in solid waste and solid-waste-related materials.", "content": "Polychlorinated biphenyls in solid waste and solid-waste-related materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204479"} {"pmid": "4204480", "title": "Effect of two isomeric tetrachlorobiphenyls on rats and their hepatic enzymes.", "content": "Effect of two isomeric tetrachlorobiphenyls on rats and their hepatic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204480"} {"pmid": "4204482", "title": "Letter: Iron absorption from skim milk enriched with iron glycerophosphate.", "content": "Letter: Iron absorption from skim milk enriched with iron glycerophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204482"} {"pmid": "4204485", "title": "The immune response of malnourished subjects with special reference to measles.", "content": "The immune response of malnourished subjects with special reference to measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204485"} {"pmid": "4204487", "title": "Pigment production by Pseudomonas reptilivora. I. Effect of iron concentration in culture media.", "content": "Pigment production by Pseudomonas reptilivora. I. Effect of iron concentration in culture media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204487"} {"pmid": "4204488", "title": "Osseous changes in congenital toxoplasmosis.", "content": "Osseous changes in congenital toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204488"} {"pmid": "4204489", "title": "Hepatitis B antigen in a leprosy hospital.", "content": "Hepatitis B antigen in a leprosy hospital. A survey of hospital patients with lepromatous and with tuberculoid leprosy showed 5% of the former and 6.3% of the latter to be carriers of hepatitis B antigen. These findings contradict the hypothesis of a genetically determined predisposition; opportunity for infection appears rather to be the determining factor. It was also found that (1) the number of carriers was higher among patients staying longer in hospital; (2) titres of antigen in patients with lepromatous leprosy were higher than in those with tuberculoid leprosy or in controls; and (3) antigen titres measured twice at an interval of 4 months indicated that the carrying of hepatitis B antigen in patients with leprosy is stable and persistent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204489"} {"pmid": "4204490", "title": "Immunogenicity of purified, inactivated chikungunya virus in monkeys.", "content": "Immunogenicity of purified, inactivated chikungunya virus in monkeys. Chikungunya (CHIK) virus, harvested from infected BHK-21 cell cultures and highly purified by a method combining zinc acetate precipitation, Sephadex-Sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (UV) irradiation and treatment with formalin. Inactivation of the virus by UV light was apparently a first-order reaction. The virus treated with 0.05% formalin at 4 degrees C was inactivated completely after 7 weeks, but when treated with 0.025% formalin retained its plaque infectivity at least 17 weeks. Both UV- and formalin-inactivated viruses induced production of anti-CHIK neutralizing antibodies in Japanese monkeys with no preimmune antibodies. Judging by the titres of antibodies produced, the immunogenic effect of the UV-irradiated virus was superior to that of the formalin-treated virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204490"} {"pmid": "4204491", "title": "A search for the epidemic typhus agent in Ethiopian ticks.", "content": "A search for the epidemic typhus agent in Ethiopian ticks. The presence of antibodies to Rickettsia prowazeki in domestic animals from several parts of Africa, and the isolation of this rickettsia from the blood of goats and sheep and from ticks off cattle or camels in Ethiopia, led to the hypothesis that R. prowazeki in nature may occur in an extrahuman cycle involving ticks and domestic animals. This study attempted to recover R. prowazeki from 2 624 ticks (4 genera, 10 species) collected in central and southern Ethiopia. The ticks were examined by the haemolymph test and by the injection of tissues into guineapigs. No strains of typhus rickettsia were received and there was no serologic evidence suggesting the presence of this agent in any of the ticks examined. One Amblyomma cohaerens contained an organism that reacted specifically with fluorescing antibodies against R. prowazeki; attempts to isolate and identify this agent failed. Fifty-seven (2.2%) Amblyomma ticks (26 A. gemma, 17 A. variegatum, 14 A. cohaerens) were infected with rickettsiae of the spotted fever group, and probably represented R. conori or closely related rickettsial agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204491"} {"pmid": "4204492", "title": "Vaccination of Rhesus monkeys (Macaca mulatta) against Plasmodium knowlesi by the use of nonviable antigen.", "content": "Vaccination of Rhesus monkeys (Macaca mulatta) against Plasmodium knowlesi by the use of nonviable antigen. This study was part of a long-term project with the ultimate goal of developing a malaria vaccine for use in man. Rhesus monkeys that had been vaccinated with a nonviable antigen given in combination with Freund's adjuvant were protected against a normally lethal challenge of Plasmodium knowlesi. Use of the antigen alone or in combination with other adjuvants was not successful. The fact that monkeys were protected against an infection that is normally lethal suggests that a similarly prepared antigen might be of use against malaria in human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204492"} {"pmid": "4204493", "title": "Studies of folic acid compounds in nature. 3. Folic acid compounds in cabbage.", "content": "Studies of folic acid compounds in nature. 3. Folic acid compounds in cabbage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204493"} {"pmid": "4204494", "title": "Effect of amino acid starvation on UV sensitivity of Lactobacillus acidophilus cells.", "content": "Effect of amino acid starvation on UV sensitivity of Lactobacillus acidophilus cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204494"} {"pmid": "4204495", "title": "Immunochemical studies on mannans of the genus Saccharomyces. Group of Torulaspora species.", "content": "Immunochemical studies on mannans of the genus Saccharomyces. Group of Torulaspora species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204495"} {"pmid": "4204497", "title": "Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor.", "content": "Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204497"} {"pmid": "4204496", "title": "Regulation of biosynthesis of secondary metabolites. XV. Isolation and characterization of auxotrophic mutants in Streptomyces aureofaciens.", "content": "Regulation of biosynthesis of secondary metabolites. XV. Isolation and characterization of auxotrophic mutants in Streptomyces aureofaciens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204496"} {"pmid": "4204498", "title": "The nerve-fiber layer of the primate retina: an autoradiographic study.", "content": "The nerve-fiber layer of the primate retina: an autoradiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204498"} {"pmid": "4204501", "title": "Report on drugs, acidic and neutral nitrogenous.", "content": "Report on drugs, acidic and neutral nitrogenous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204501"} {"pmid": "4204502", "title": "Report on multiresidue methods (interlaboratory studies).", "content": "Report on multiresidue methods (interlaboratory studies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204502"} {"pmid": "4204503", "title": "Reverse phase thin layer chromatography of some aroclors, halowaxes, and pesticides.", "content": "Reverse phase thin layer chromatography of some aroclors, halowaxes, and pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204503"} {"pmid": "4204504", "title": "Ceramic-coated subperiosteal implants. II. Clinical and histologic evaluations.", "content": "Ceramic-coated subperiosteal implants. II. Clinical and histologic evaluations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204504"} {"pmid": "4204505", "title": "The activation of mononuclear phagocytes in vitro: immunologically mediated enhancement.", "content": "The activation of mononuclear phagocytes in vitro: immunologically mediated enhancement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204505"} {"pmid": "4204506", "title": "Neurogenic influence on pulmonary compliance.", "content": "Neurogenic influence on pulmonary compliance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204506"} {"pmid": "4204507", "title": "Pharmacologic increases in erythrocyte 2,3-diphosphoglycerate for therapeutic benefit.", "content": "Pharmacologic increases in erythrocyte 2,3-diphosphoglycerate for therapeutic benefit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204507"} {"pmid": "4204499", "title": "Direct determination of carbaryl by gas-liquid chromatography using electron capture detection.", "content": "Direct determination of carbaryl by gas-liquid chromatography using electron capture detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204499"} {"pmid": "4204500", "title": "Photoreduction of 4,4'-dichlorobiphenyl.", "content": "Photoreduction of 4,4'-dichlorobiphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204500"} {"pmid": "4204517", "title": "The relationship of NSD to reactions and complications following treatment for malignant uterine cervical neoplasms.", "content": "The relationship of NSD to reactions and complications following treatment for malignant uterine cervical neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204517"} {"pmid": "4204516", "title": "Periosteal new bone formation (periosteal neostosis) in renal osteodystrophy. Relationship to osteosclerosis, osteitis fibrosa, and osteoid excess.", "content": "Periosteal new bone formation (periosteal neostosis) in renal osteodystrophy. Relationship to osteosclerosis, osteitis fibrosa, and osteoid excess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204516"} {"pmid": "4204519", "title": "Australia antigen in patients with viral hepatitis.", "content": "Australia antigen in patients with viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204519"} {"pmid": "4204518", "title": "Rickettsioses in Dalmatia (Yugoslavia).", "content": "Rickettsioses in Dalmatia (Yugoslavia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204518"} {"pmid": "4204511", "title": "Criteria for an animal model of alcoholism.", "content": "Criteria for an animal model of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204511"} {"pmid": "4204522", "title": "Sciatic nerve entrapment by ectopic bone after posterior fracture-dislocation of the hip.", "content": "Sciatic nerve entrapment by ectopic bone after posterior fracture-dislocation of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204522"} {"pmid": "4204523", "title": "On T-cell-mediated cytotoxicity.", "content": "On T-cell-mediated cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204523"} {"pmid": "4204524", "title": "New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression.", "content": "New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204524"} {"pmid": "4204512", "title": "Heart rate and respiratory rate changes during drug-induced impairment in a conditioned avoidance task in monkeys.", "content": "Heart rate and respiratory rate changes during drug-induced impairment in a conditioned avoidance task in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204512"} {"pmid": "4204515", "title": "A review of methods to induce alcohol addiction in animals.", "content": "A review of methods to induce alcohol addiction in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204515"} {"pmid": "4204525", "title": "Human uromucoid. I. Quantitative immunoassay.", "content": "Human uromucoid. I. Quantitative immunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204525"} {"pmid": "4204527", "title": "Functional units of Streptomyces hyphae, equivalent with prokaryotic cells.", "content": "Functional units of Streptomyces hyphae, equivalent with prokaryotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204527"} {"pmid": "4204513", "title": "A comparison of d-amphetamine, l-amphetamine, and methamphetamine self-administration in rhesus monkeys.", "content": "A comparison of d-amphetamine, l-amphetamine, and methamphetamine self-administration in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204513"} {"pmid": "4204514", "title": "Evidence for ascending noradrenergic mediation of hypothalamic hyperphagia.", "content": "Evidence for ascending noradrenergic mediation of hypothalamic hyperphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204514"} {"pmid": "4204526", "title": "Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs.", "content": "Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204526"} {"pmid": "4204530", "title": "A simple passive hemagglutination-inhibition technic for determination of fibrin degradation products and fibrinogen.", "content": "A simple passive hemagglutination-inhibition technic for determination of fibrin degradation products and fibrinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204530"} {"pmid": "4204531", "title": "Another example of anti-D in a D-positive patient.", "content": "Another example of anti-D in a D-positive patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204531"} {"pmid": "4204532", "title": "Isolation of Neisseria meningitidis from the vagina and cervix.", "content": "Isolation of Neisseria meningitidis from the vagina and cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204532"} {"pmid": "4204533", "title": "Aspergillus myocarditis.", "content": "Aspergillus myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204533"} {"pmid": "4204534", "title": "Heritability estimates and genetic and environmental correlations for the human immunoglobulins G, M, and A.", "content": "Heritability estimates and genetic and environmental correlations for the human immunoglobulins G, M, and A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204534"} {"pmid": "4204535", "title": "Blood groups and immunoglobulin groups in Trio and Wajana Indians from Surinam.", "content": "Blood groups and immunoglobulin groups in Trio and Wajana Indians from Surinam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204535"} {"pmid": "4204536", "title": "Position of the Duffy locus on chromosome 1 in relation to breakpoints for structural rearrangements.", "content": "Position of the Duffy locus on chromosome 1 in relation to breakpoints for structural rearrangements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204536"} {"pmid": "4204537", "title": "Evolving health delivery systems and older people.", "content": "Evolving health delivery systems and older people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204537"} {"pmid": "4204538", "title": "The fastest growing minority: the aging.", "content": "The fastest growing minority: the aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204538"} {"pmid": "4204539", "title": "Health services: their success and failure in reaching older adults.", "content": "Health services: their success and failure in reaching older adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204539"} {"pmid": "4204540", "title": "Health status of older people: cross-national implications.", "content": "Health status of older people: cross-national implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204540"} {"pmid": "4204541", "title": "Rifampin in initial treatment of pulmonary tuberculosis. A.U.S. Public Health Service tuberculosis therapy trial.", "content": "Rifampin in initial treatment of pulmonary tuberculosis. A.U.S. Public Health Service tuberculosis therapy trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204541"} {"pmid": "4204543", "title": "Bacteriocin-typing of Mycobacterium tuberculosis.", "content": "Bacteriocin-typing of Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204543"} {"pmid": "4204542", "title": "Osteomyelitis caused by concurrent infection with Mycobacterium tuberculosis and Blastomyces dermatitidis.", "content": "Osteomyelitis caused by concurrent infection with Mycobacterium tuberculosis and Blastomyces dermatitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204542"} {"pmid": "4204545", "title": "Thyroxine transport and metabolism in methadone and heroin addicts.", "content": "Thyroxine transport and metabolism in methadone and heroin addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204545"} {"pmid": "4204546", "title": "The plasminogen activator of vampire bat saliva.", "content": "The plasminogen activator of vampire bat saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204546"} {"pmid": "4204547", "title": "The relationship between the urethral flora and urinary infection in the catheterised male.", "content": "The relationship between the urethral flora and urinary infection in the catheterised male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204547"} {"pmid": "4204548", "title": "Effect of phenobarbitone on plasma (14C)bilirubin clearance in patients with unconjugated hyperbilirubinaemia.", "content": "Effect of phenobarbitone on plasma (14C)bilirubin clearance in patients with unconjugated hyperbilirubinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204548"} {"pmid": "4204551", "title": "Unsaturated fatty acid synthesis is not required for induction of lactose transport in Escherichia coli.", "content": "Unsaturated fatty acid synthesis is not required for induction of lactose transport in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204551"} {"pmid": "4204552", "title": "Purification and properties of an endo-beta-N-acetylglucosaminidase from Streptomyces griseus.", "content": "Purification and properties of an endo-beta-N-acetylglucosaminidase from Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204552"} {"pmid": "4204549", "title": "Recombination at the bar locus in an inverted attached-X system in Drosophila melanogaster.", "content": "Recombination at the bar locus in an inverted attached-X system in Drosophila melanogaster. Recombination at the Bar locus in Drosophila melanogaster was investigated in an inverted attached-X system which enhanced the frequency of homozygosis for the Bar region. Females among the progeny of homozygous B mothers were searched for changes of B to BB and to B(+). Marker genes were followed and exceptional half-tetrads were analyzed in regard to two hypotheses: that of exchange between obliquely synapsed members of the duplication, which is associated with exchange of outside markers, and that of intrachromosomal exchange, which does not involve recombination of markers.-Recombinant exceptions of B(+) /BB genotype, carrying the outside marker combinations predicted on the hypothesis of exchange between obliquely synapsed duplication members, were encountered repeatedly. It is established that B(+) and BB strands are reciprocal products of the same event.-Twelve nonrecombinant exceptional strands were isolated; ten of these were B(+) and two were BB. Only one of the nonrecombinant half-tetrads offered the opportunity to test the prediction of reciprocity of the intrachromosomal event. Analysis showed the exceptional female to be of the constitution BB/B, a type not expected on the hypothesis. While it could have arisen through some kind of copy error in the repair of a chromatid break, a valid test of the hypothesis of intrachromosomal exchange must rest on the isolation and analysis of more cases of the appropriate exceptional genotype.-In several cases Bar changes were found to be associated with aberrations; all but one of these involved spontaneous, cytologically identifiable deletions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204549"} {"pmid": "4204550", "title": "Heterogeneity of echovirus type 17: comparison of the two lines of the prototype strain.", "content": "Heterogeneity of echovirus type 17: comparison of the two lines of the prototype strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204550"} {"pmid": "4204553", "title": "The release of intact oligosaccharides from specific glycoproteins by endo-beta-N-acetylglucosaminidase H.", "content": "The release of intact oligosaccharides from specific glycoproteins by endo-beta-N-acetylglucosaminidase H.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204553"} {"pmid": "4204554", "title": "The structural gene for O-acetylserine sulfhydrylase A in Salmonella typhimurium. Identity with the trzA locus.", "content": "The structural gene for O-acetylserine sulfhydrylase A in Salmonella typhimurium. Identity with the trzA locus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204554"} {"pmid": "4204555", "title": "Isolation of a second form of calsequestrin.", "content": "Isolation of a second form of calsequestrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204555"} {"pmid": "4204556", "title": "Morphology of the inferior olivary complex of the rhesus monkey (Macaca mulatta).", "content": "Morphology of the inferior olivary complex of the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204556"} {"pmid": "4204557", "title": "Comparison of the infectivity and pathogenicity of six species of African schistosomes and their hybrids. 2. Baboons.", "content": "Comparison of the infectivity and pathogenicity of six species of African schistosomes and their hybrids. 2. Baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204557"} {"pmid": "4204558", "title": "Isolation and characterization of a blood P1 active carbohydrate antigen of Echinococcus granulosus cyst membrane.", "content": "Isolation and characterization of a blood P1 active carbohydrate antigen of Echinococcus granulosus cyst membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204558"} {"pmid": "4204559", "title": "A potent non-peroxidase glycoprotein immunogen in commercial horseradish peroxidase.", "content": "A potent non-peroxidase glycoprotein immunogen in commercial horseradish peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204559"} {"pmid": "4204561", "title": "Fractionation of sera from operationally tolerant rats by DEAE cellulose chromatography; evidence that serum blocking factors are associated with IgG.", "content": "Fractionation of sera from operationally tolerant rats by DEAE cellulose chromatography; evidence that serum blocking factors are associated with IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204561"} {"pmid": "4204560", "title": "A functional abnormality of the fifth component of complement (C5) from human serum of individuals with a familial opsonic defect.", "content": "A functional abnormality of the fifth component of complement (C5) from human serum of individuals with a familial opsonic defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204560"} {"pmid": "4204562", "title": "Rabbit secretory IgA: identification and genetic control of two allotypes of secretory component.", "content": "Rabbit secretory IgA: identification and genetic control of two allotypes of secretory component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204562"} {"pmid": "4204563", "title": "Autoimmune murine thyroiditis. IV. Localization of genetic control of the immune response.", "content": "Autoimmune murine thyroiditis. IV. Localization of genetic control of the immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204563"} {"pmid": "4204564", "title": "Counterimmunoelectrophoresis with adenovirus type-specific anti-hemagglutinin sera as a rapid diagnostic method.", "content": "Counterimmunoelectrophoresis with adenovirus type-specific anti-hemagglutinin sera as a rapid diagnostic method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204564"} {"pmid": "4204565", "title": "Differential contributions of spinal pathways to body representation in postcentral gyrus of Macaca mulatta.", "content": "Differential contributions of spinal pathways to body representation in postcentral gyrus of Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204565"} {"pmid": "4204566", "title": "Response characteristics of single cells in the monkey superior colliculus following ablation or cooling of visual cortex.", "content": "Response characteristics of single cells in the monkey superior colliculus following ablation or cooling of visual cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204566"} {"pmid": "4204567", "title": "Reconstruction of population response to a vibratory stimulus in quickly adapting mechanoreceptive afferent fiber population innervating glabrous skin of the monkey.", "content": "Reconstruction of population response to a vibratory stimulus in quickly adapting mechanoreceptive afferent fiber population innervating glabrous skin of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204567"} {"pmid": "4204568", "title": "Evidence for an endogenous antigen in the adjuvant arthritic rat.", "content": "Evidence for an endogenous antigen in the adjuvant arthritic rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204568"} {"pmid": "4204569", "title": "Adrenal function in normal infants and in marasmus and kwashiorkor: plasma aldosterone concentration and aldosterone secretion rate.", "content": "Adrenal function in normal infants and in marasmus and kwashiorkor: plasma aldosterone concentration and aldosterone secretion rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204569"} {"pmid": "4204571", "title": "Letter: Wheat farmer's asthma in Australia.", "content": "Letter: Wheat farmer's asthma in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204571"} {"pmid": "4204573", "title": "Glucose intolerance in infants of very low birth weight. I. Incidence of hyperglycemia in infants of birth weights 1,100 grams or less.", "content": "Glucose intolerance in infants of very low birth weight. I. Incidence of hyperglycemia in infants of birth weights 1,100 grams or less.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204573"} {"pmid": "4204574", "title": "Total and free thyroid hormone concentrations in the neonatal period.", "content": "Total and free thyroid hormone concentrations in the neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204574"} {"pmid": "4204575", "title": "Custody of the myelodysplastic child: implications for selection for early treatment.", "content": "Custody of the myelodysplastic child: implications for selection for early treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204575"} {"pmid": "4204577", "title": "Separation of photosynthetic systems I and II.", "content": "Separation of photosynthetic systems I and II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204577"} {"pmid": "4204578", "title": "7S immunoglobulin M (IgM) from serum purified by anti-mu-chain immunoadsorbent: comparison of the reassociation properties of 7S IgM and various 19S IgM subunits.", "content": "7S immunoglobulin M (IgM) from serum purified by anti-mu-chain immunoadsorbent: comparison of the reassociation properties of 7S IgM and various 19S IgM subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204578"} {"pmid": "4204579", "title": "Low-molecular-weight antibody in rabbit urine: identity with the Fab immunoglobulin fragment.", "content": "Low-molecular-weight antibody in rabbit urine: identity with the Fab immunoglobulin fragment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204579"} {"pmid": "4204580", "title": "Studies on viral hepatitis and hepatitis B (Australia) antigen.", "content": "Studies on viral hepatitis and hepatitis B (Australia) antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204580"} {"pmid": "4204581", "title": "Ecto-enzyme of granulocytes: 5'-nucleotidase.", "content": "Ecto-enzyme of granulocytes: 5'-nucleotidase. The 5'-nucleotidase of guinea pig polymorphonuclear leukocytes is localized exclusively on the plasma membrane of intact cells. The active site of this enzyme faces the external medium, not the cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204581"} {"pmid": "4204582", "title": "Synthesis and expression of surface antigens during the cell cycle.", "content": "Synthesis and expression of surface antigens during the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204582"} {"pmid": "4204576", "title": "Development of functional tolerance to ethanol in rhesus monkeys (Macaca mulatta).", "content": "Development of functional tolerance to ethanol in rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204576"} {"pmid": "4204588", "title": "B and T cell markers in human proliferative blood diseases and primary immunodeficiencies, with special reference to membrane bound immunoglobulins.", "content": "B and T cell markers in human proliferative blood diseases and primary immunodeficiencies, with special reference to membrane bound immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204588"} {"pmid": "4204591", "title": "Juvenile xanthogranuloma diagnosed by paracentesis.", "content": "Juvenile xanthogranuloma diagnosed by paracentesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204591"} {"pmid": "4204590", "title": "Variant angina pectoris caused by coronary artery spasm.", "content": "Variant angina pectoris caused by coronary artery spasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204590"} {"pmid": "4204592", "title": "Ocular toxicity from ethambutol.", "content": "Ocular toxicity from ethambutol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204592"} {"pmid": "4204593", "title": "Use of chemically defined diets in the management of patients with high output gastrointestinal cutaneous fistulas.", "content": "Use of chemically defined diets in the management of patients with high output gastrointestinal cutaneous fistulas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204593"} {"pmid": "4204594", "title": "Changing methods in the treatment of severe pancreatitis.", "content": "Changing methods in the treatment of severe pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204594"} {"pmid": "4204595", "title": "Further studies on nicotine-induced alterations in histamine metabolism in the rat.", "content": "Further studies on nicotine-induced alterations in histamine metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204595"} {"pmid": "4204583", "title": "The high incidence of anti-HL-A antibodies in anti-D typing reagents. Illustrated by a case of Matuhasi-Ogata phenomenon mimicking a \"D with anti-D\" situation.", "content": "The high incidence of anti-HL-A antibodies in anti-D typing reagents. Illustrated by a case of Matuhasi-Ogata phenomenon mimicking a \"D with anti-D\" situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204583"} {"pmid": "4204596", "title": "Tonsillectomies: in dollars and cents.", "content": "Tonsillectomies: in dollars and cents. Over the last quarter of a century, much controversy has been generated on the indications for tonsillectomy and adenoidectomy. The economic aspects of this operation have received comparatively little attention. The rate per 10,000 children 0 to 19 years of age for the whole province of Ontario for the year 1971 was 174 and ranged from a high of 307 in one county to a low of 59 in another. The total cost of these operations to the health insurance plan was 11.4 million dollars. National studies on the indications for these operations, their benefits and hazards are urgently required.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204596"} {"pmid": "4204597", "title": "Metabolic studies on polychlorinated biphenyls. II. Metabolic fate of 2,4,3',4'-tetrachlorobiphenyl in rats.", "content": "Metabolic studies on polychlorinated biphenyls. II. Metabolic fate of 2,4,3',4'-tetrachlorobiphenyl in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204597"} {"pmid": "4204598", "title": "Metabolic studies on polychlorinated biphenyls. 3. Complete structure and acute toxicity of the metabolites of 2,4,3',4'-tetrachlorobiphenyl.", "content": "Metabolic studies on polychlorinated biphenyls. 3. Complete structure and acute toxicity of the metabolites of 2,4,3',4'-tetrachlorobiphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204598"} {"pmid": "4204584", "title": "The influence of dialysis in 2-mercaptoethanol reduction of erythrocyte antibodies.", "content": "The influence of dialysis in 2-mercaptoethanol reduction of erythrocyte antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204584"} {"pmid": "4204586", "title": "Hepatitis carriers among soldiers who have returned from Vietnam. Australia antigen studies.", "content": "Hepatitis carriers among soldiers who have returned from Vietnam. Australia antigen studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204586"} {"pmid": "4204600", "title": "Letter: The cell division of the pigment epithelium in the repairing retina after photocoagulation.", "content": "Letter: The cell division of the pigment epithelium in the repairing retina after photocoagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204600"} {"pmid": "4204599", "title": "Congenital pseudarthrosis of the radius.", "content": "Congenital pseudarthrosis of the radius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204599"} {"pmid": "4204585", "title": "Pseudomonas septicemia in neutropenic dogs. I. Treatment with granulocyte transfusions.", "content": "Pseudomonas septicemia in neutropenic dogs. I. Treatment with granulocyte transfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204585"} {"pmid": "4204601", "title": "Immune response of pathogen-free mice inoculated intranasally with Mycoplasma pulmonis.", "content": "Immune response of pathogen-free mice inoculated intranasally with Mycoplasma pulmonis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204601"} {"pmid": "4204587", "title": "Evaluation of the use of albumin controls in Rh phenotyping.", "content": "Evaluation of the use of albumin controls in Rh phenotyping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204587"} {"pmid": "4204603", "title": "The association of J chain with the Fc region of human IgM.", "content": "The association of J chain with the Fc region of human IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204603"} {"pmid": "4204602", "title": "Human J-chain: isolation and molecular weight studies.", "content": "Human J-chain: isolation and molecular weight studies. J-chain, a polypeptide chain unique to polymeric immunoglobulins (Igs) which has been postulated to be responsible for joining monomeric subunits into the polymeric forms, was isolated from human IgA, secretory IgA, and IgM by 3 different procedures, disc electrophoresis, immunoadsorbent radioimmunoassay, and dialysis against distilled water. Precipitation in water was the simplest and yielded satisfactory results. Molecular weights of the various J-chain isolates were studied by using 2-species plot analysis of sedimentation equilibrium data. 2 populations of molecules were found: 1 had a molecular weight of 13,300-17,700 and the other of 6400-11,500. Variations in these data from those of other investigators are discussed in terms of isolation procedure differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204602"} {"pmid": "4204604", "title": "Isolation and characterization of the proenzyme form of the C1s subunit of the first complement component.", "content": "Isolation and characterization of the proenzyme form of the C1s subunit of the first complement component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204604"} {"pmid": "4204606", "title": "Antigenicity of reduced and alkylated Australia antigen.", "content": "Antigenicity of reduced and alkylated Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204606"} {"pmid": "4204605", "title": "Membrane receptors and in vitro responsiveness of lymphocytes in human immunodeficiency.", "content": "Membrane receptors and in vitro responsiveness of lymphocytes in human immunodeficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204605"} {"pmid": "4204607", "title": "Immunoglobulins in CSF in multiple sclerosis and other neurological disorders.", "content": "Immunoglobulins in CSF in multiple sclerosis and other neurological disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204607"} {"pmid": "4204614", "title": "Letter: Intal in childhood asthma.", "content": "Letter: Intal in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204614"} {"pmid": "4204617", "title": "The baboon. Hematology.", "content": "The baboon. Hematology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204617"} {"pmid": "4204616", "title": "The baboon. Clinical chemistry.", "content": "The baboon. Clinical chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204616"} {"pmid": "4204618", "title": "The baboon. Parasitology.", "content": "The baboon. Parasitology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204618"} {"pmid": "4204620", "title": "Immunosuppressive activity of the Pseudomonas aeruginosa endotoxin on a lysozyme anti-lysozyme system.", "content": "Immunosuppressive activity of the Pseudomonas aeruginosa endotoxin on a lysozyme anti-lysozyme system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204620"} {"pmid": "4204621", "title": "Phenoloxidase system in wild and mutant adults of drosophila melanogaster. I. Activation and activity of mono- and diphenoloxidases.", "content": "Phenoloxidase system in wild and mutant adults of drosophila melanogaster. I. Activation and activity of mono- and diphenoloxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204621"} {"pmid": "4204622", "title": "Ribonucleoprotein particles containing mRNA and pre-mRNA.", "content": "Ribonucleoprotein particles containing mRNA and pre-mRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204622"} {"pmid": "4204623", "title": "Non-ribosomal polypeptide synthesis.", "content": "Non-ribosomal polypeptide synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204623"} {"pmid": "4204624", "title": "Specific secretory protein of the female genital tract.", "content": "Specific secretory protein of the female genital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204624"} {"pmid": "4204625", "title": "Protein synthesis in mammary gland.", "content": "Protein synthesis in mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204625"} {"pmid": "4204626", "title": "Monoamine-containing cell bodies in the squirrel monkey brain.", "content": "Monoamine-containing cell bodies in the squirrel monkey brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204626"} {"pmid": "4204627", "title": "Osteoradionecrosis of the jaw.", "content": "Osteoradionecrosis of the jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204627"} {"pmid": "4204630", "title": "The influence of oxygen on the fluorescence of lipoxygenase.", "content": "The influence of oxygen on the fluorescence of lipoxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204630"} {"pmid": "4204629", "title": "Effect of mirex on the activities of various rat hepatic mixed-function oxidases.", "content": "Effect of mirex on the activities of various rat hepatic mixed-function oxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204629"} {"pmid": "4204631", "title": "The conversion of bisnorbiotin and bisnordethiobiotin to biotin and dethiobiotin, respectively, by microorganisms.", "content": "The conversion of bisnorbiotin and bisnordethiobiotin to biotin and dethiobiotin, respectively, by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204631"} {"pmid": "4204632", "title": "Immunochemistry of sperm-whale myoglobin. XVII. Conformation and immunochemistry of derivatives modified at lysines 98, 140 and 145 by reaction with 3,3-tetramethyleneglutaric anhydride.", "content": "Immunochemistry of sperm-whale myoglobin. XVII. Conformation and immunochemistry of derivatives modified at lysines 98, 140 and 145 by reaction with 3,3-tetramethyleneglutaric anhydride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204632"} {"pmid": "4204633", "title": "Heat denaturation of bovine serum albumin in alkaline pH region.", "content": "Heat denaturation of bovine serum albumin in alkaline pH region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204633"} {"pmid": "4204634", "title": "Conformational change of bovine serum albumin induced by O.IO m Tris-EDTA-boric acid buffer at pH9.", "content": "Conformational change of bovine serum albumin induced by O.IO m Tris-EDTA-boric acid buffer at pH9.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204634"} {"pmid": "4204635", "title": "Vitamin B12 binding proteins in monkey serum and red cells.", "content": "Vitamin B12 binding proteins in monkey serum and red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204635"} {"pmid": "4204636", "title": "Snake venom toxins. The amino acid sequences of two toxins from Dendroaspis jamesoni kaimosae (Jameson's mamba) venom.", "content": "Snake venom toxins. The amino acid sequences of two toxins from Dendroaspis jamesoni kaimosae (Jameson's mamba) venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204636"} {"pmid": "4204638", "title": "Compensatory renal hypertrophy in eviscerated rats.", "content": "Compensatory renal hypertrophy in eviscerated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204638"} {"pmid": "4204639", "title": "Olfactory recognition in the infant squirrel monkey.", "content": "Olfactory recognition in the infant squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204639"} {"pmid": "4204640", "title": "Growth and behavior of surrogate-reared squirrel monkeys.", "content": "Growth and behavior of surrogate-reared squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204640"} {"pmid": "4204641", "title": "Non-specific immunologic precipitin reactions in alpha-fetoprotein determination. Analysis of two cases.", "content": "Non-specific immunologic precipitin reactions in alpha-fetoprotein determination. Analysis of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204641"} {"pmid": "4204646", "title": "Problems in the definition of ill health.", "content": "Problems in the definition of ill health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204646"} {"pmid": "4204648", "title": "A simple method of preparation of gastrointestinal tract tissues for scanning electron microscopy.", "content": "A simple method of preparation of gastrointestinal tract tissues for scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204648"} {"pmid": "4204647", "title": "Perinatal immunity in calves.", "content": "Perinatal immunity in calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204647"} {"pmid": "4204649", "title": "The stability of second-order conditioned limb responses established in hens with cerebral electrical stimuli.", "content": "The stability of second-order conditioned limb responses established in hens with cerebral electrical stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204649"} {"pmid": "4204650", "title": "Rheumatic fever presenting as an acute abdomen.", "content": "Rheumatic fever presenting as an acute abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204650"} {"pmid": "4204651", "title": "Alterations of serum opsonins in patients with severe thermal injury.", "content": "Alterations of serum opsonins in patients with severe thermal injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204651"} {"pmid": "4204652", "title": "Erythroblast ferritin: synthesis, structure, and function in developing erythroid cells.", "content": "Erythroblast ferritin: synthesis, structure, and function in developing erythroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204652"} {"pmid": "4204653", "title": "The kinetics of 67gallium incorporation into inflammatory lesions: experimental and clinical studies.", "content": "The kinetics of 67gallium incorporation into inflammatory lesions: experimental and clinical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204653"} {"pmid": "4204654", "title": "A new look at mumps encephalitis: inclusion bodies and cytopathic effects.", "content": "A new look at mumps encephalitis: inclusion bodies and cytopathic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204654"} {"pmid": "4204656", "title": "Diarrhea toxin obtained from a waterbloom-producing species, Microcystis aeruginosA Kützing.", "content": "Diarrhea toxin obtained from a waterbloom-producing species, Microcystis aeruginosA Kützing. A diarrhea-producing toxin from a blue-green alga, Microcystis aeruginosa Kützing, was obtained from standing laboratory cultures. The non-dialyzable fraction of the lysate from whole cells produced fluid accumulation in the ligated small intestinal loops in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204656"} {"pmid": "4204659", "title": "Teratogenic effects of aldrin, dieldrin, and endrin in hamsters and mice.", "content": "Teratogenic effects of aldrin, dieldrin, and endrin in hamsters and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204659"} {"pmid": "4204660", "title": "Teratogenic effects of ochratoxin A in mice.", "content": "Teratogenic effects of ochratoxin A in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204660"} {"pmid": "4204661", "title": "Critical point drying of protozoan cells and other biological specimens for scanning electron microscopy: apparatus and methods of specimen preparation.", "content": "Critical point drying of protozoan cells and other biological specimens for scanning electron microscopy: apparatus and methods of specimen preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204661"} {"pmid": "4204665", "title": "The variant form of angina: diagnostic and therapeutic implications.", "content": "The variant form of angina: diagnostic and therapeutic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204665"} {"pmid": "4204667", "title": "Animal reservoirs and Gambian trypanosomiasis.", "content": "Animal reservoirs and Gambian trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204667"} {"pmid": "4204668", "title": "Nephrogenic diabetes insipidus secondary to declomycin.", "content": "Nephrogenic diabetes insipidus secondary to declomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204668"} {"pmid": "4204669", "title": "Steady-state enzyme kinetics with high-affinity substrates or inhibitors. A statistical treatment of dose-response curves.", "content": "Steady-state enzyme kinetics with high-affinity substrates or inhibitors. A statistical treatment of dose-response curves. A statistical treatment of steady-state enzyme kinetic measurements is described that allows for depletion of free substrate or free inhibitor concentrations owing to significant binding to the enzyme. V(max.), K(m) or K(i), enzyme concentration, the concentration of substrate or inhibitor required for a half-maximal effect and standard errors of these parameters can be calculated from dose-response measurements; the concentration of each component of the system may be estimated also. The statistically best values of the parameters are used to convert dose-response curves into convenient linear forms. The method is applied to dose-response measurements of hydroxyquinoline N-oxide inhibition of bacterial respiration and aminopterin inhibition of dihydrofolate reductase. Two FORTRAN programs for this method have been deposited as Supplementary Publication no. SUP 50019 at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms indicated in Biochem. J. (1973) 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204669"} {"pmid": "4204671", "title": "Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia.", "content": "Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204671"} {"pmid": "4204670", "title": "Gastrointestinal problems in the old. II.", "content": "Gastrointestinal problems in the old. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204670"} {"pmid": "4204672", "title": "Specific lymphocyte stimulation by purified, heat-inactivated hepatitis-B antigen.", "content": "Specific lymphocyte stimulation by purified, heat-inactivated hepatitis-B antigen. The ability of purified, heat-inactivated hepatitis-B antigen (HBAg) to stimulate sensitized lymphocytes in vitro was investigated with the lymphocyte stimulation test on lymphocytes from three groups of individuals. Stimulation was minimal in the lymphocytes of two out of 15 normal controls, whereas lymphocytes from nine out of 12 patients who had recovered from hepatitis B showed stimulation, as did lymphocytes from five out of 12 laboratory technicians who had been regularly exposed to HBAg but who had no history of hepatitis or signs of it in the previous two years. No differences were observed in the responses to phytohaemagglutinin of lymphocytes from persons in the three groups. HBAg and HBAg inactivated by heat were shown in immunodiffusion to be immunologically identical. Inactivated HBAg stimulated antibody production in guinea-pigs. These findings suggest that not only humoral but also cell-mediated immunity might be induced by vaccination with purified, heat-inactivated HBAg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204672"} {"pmid": "4204673", "title": "Use of Tenckhoff catheter for peritoneal dialysis in terminal renal failure.", "content": "Use of Tenckhoff catheter for peritoneal dialysis in terminal renal failure. Over a period of 33 months a total of 2,146 peritoneal dialyses were carried out by means of indwelling Tenckhoff catheters in 65 patients suffering from terminal renal failure. The patients were maintained on peritoneal dialysis for periods varying from two weeks to 13 months. Treatment over long periods was possible in only a few cases. Infection and clotting, which tended to limit the functional life of the catheters, was reduced by rigid asepsis and by adding heparin to the dialysate. The Tenckhoff catheter was found to be valuable for peritoneal dialysis as a short-term measure, especially in patients in whom haemodialysis was not immediately feasible, in borderline cases when kidney function was not too seriously impaired, and as an alternative to haemodialysis when that was interrupted by complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204673"} {"pmid": "4204681", "title": "Sulfuric acid for the cleanup of animal tissues for analysis of acid-stable chlorinated hydrocarbon residues.", "content": "Sulfuric acid for the cleanup of animal tissues for analysis of acid-stable chlorinated hydrocarbon residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204681"} {"pmid": "4204675", "title": "Cancer statistics, 1974--worldwide epidemiology.", "content": "Cancer statistics, 1974--worldwide epidemiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204675"} {"pmid": "4204674", "title": "Detection of cervical neoplasia: reducing the risk of error.", "content": "Detection of cervical neoplasia: reducing the risk of error. In cytology studies false negative smears range from 1.8% to 20% due to different levels of cytologic expertise and of material presented to the pathologist. Only 6% of in situ carcinomas of the cervix have an abnormal gross appearance so routine multiple biopsies are needed. Schiller's test, using a weak aqueous solution of iodine, leaves an area of carcinoma unstained but colors normal cervical epithelium a dark brown. However, not all areas which fail to stain represent foci of cancer. Multiple biopsies and endocervical curettage are required, particularly to detect lesions not involving the portio. Conization is the most accurate method for evaluating the suspicious cervix. 80 histo logic sections should be examined from each cervix specimen. Complicati ons of conization may be hemorrhage, cervical stenosis, uterine perforation, and pelvic infection. Only after 4-6 weeks does pelvic infection cease to be a significant risk. When done during pregnancy, conization may cause a fetal loss of 15%. Colposcopy has a low false-negative rate but cannot detect lesions inside the cervical canal. It is the best method of clinical evaluation of patients with abnormal cytological smears, particularly during pregnancy. A colposcopic diagnosis is based on an evaluation of vascular pattern, intercapillary distance, surface contour, color tone, and clarity of demarcation. Where colposcopic examination is unsatisfactory and cytology is positive, conization is indicated. The final diagnosis depends on the histology of the directed biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204674"} {"pmid": "4204685", "title": "Three-dimensional structures of giant mitochondria, dictyosomes and \"concentric lamellar bodies\" formed during the cell cycle of Euglena gracilis (Z) in synchronous culture.", "content": "Three-dimensional structures of giant mitochondria, dictyosomes and \"concentric lamellar bodies\" formed during the cell cycle of Euglena gracilis (Z) in synchronous culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204685"} {"pmid": "4204682", "title": "Removing substances from blood by affinity chromatography. I. Removing bilirubin and other albumin-bound substances from plasma and blood with albumin-conjugated agarose beads.", "content": "Removing substances from blood by affinity chromatography. I. Removing bilirubin and other albumin-bound substances from plasma and blood with albumin-conjugated agarose beads. Substances such as bilirubin that bind tightly to plasma proteins cannot readily be removed from blood. We describe here the use of affinity chromatography as a new approach to the removal of proteinbound metabolites and toxins from blood. Agarose beads were coupled via cyanogen bromide to human serum albumin so as to contain 30-50 mg of albumin/g wet wt. Such beads, when exposed to plasma from a patient with congenital nonhemolytic jaundice labeled with [(14)C]-bilirubin, bound more than 150 mug bilirubin/g of beads. The binding was saturable, concentration-dependent, relatively independent of flow rate, and reversible by elution with plasma, albumin, or 50% (vol/vol) ethanol. The beads could be repeatedly reused without loss of efficiency after ethanol elution and long storage in the cold. Salicylate, cortisol, and taurocholate, which bind weakly to albumin, were retarded by the beads but eluted with neutral buffer. Thyroxine, taurolithocholate, chenodeoxycholate, and digitoxin bound tightly but were eluted with 50% ethanol. Digoxin did not bind at all. When whole blood was passed over agarose-albumin beads, bilirubin was removed, calcium and magnesium fell slightly, but red cells, white cells, platelets, clotting factors, and a variety of electrolytes and proteins were substantially unchanged. Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits. Furthermore, it may be possible to make useful adsorbents by attaching other proteins to agarose or other polymer beads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204682"} {"pmid": "4204683", "title": "Isolation of a novel glycoprotein from the urine of a patient with chronic myelocytic leukemia.", "content": "Isolation of a novel glycoprotein from the urine of a patient with chronic myelocytic leukemia. Patient B. J. with chronic myelocytic leukemia excreted 0.5-1.1 g protein per day in the urine. Gel filtration on Sephadex G-75 showed about one-third of this protein to be in molecular weight range 20,000-40,000 (fraction BJC). BJC, prepared from 9 liters of urine by gel filtration, was chromatographed on carboxymethylcellulose. Two proteins were eluted from the resin in pure form (as shown by zone and immunoelectrophoresis) in yields representing 8 and 3 mg/liter of urine: BJC1 and BJC2. Their amino acid compositions were identical. BJC1 contained 61% carbohydrate (33% hexose, 11% sialic acid, 13% glucosamine, 5% galactosamine). BJC2 contained one-fourth to one-half as much of each carbohydrate. Molecular weight of BJC1 was estimated at 29,000 by gel filtration. Neither glycoprotein reacted with rabbit antiserum to normal human serum.Antiserum to BJC1 was made in the rabbit. Immunoelectrophoresis with this antiserum showed a faint precipitin line, corresponding in mobility to BJC1, in normal human plasma, and a stronger line in most leukemic plasmas. By immunodiffusion, BJC1 was not detectable in normal human urine, but a positive reaction occurred in the following conditions: leukemia, 64-72%; other types of disseminated neoplastic disease, 36-78%; regional ileitis, 45%; ulcerative colitis, 38%; tuberculosis, 33%; during the 1st wk after major surgery, 33%.BJC2 was found in the urine by immunoelectrophoresis in 10% of patients with neoplastic disease and was not observed in urine of other patients or in human plasma. Amino acid composition, carbohydrate content, and antigenic specificity indicate BJC1 is a previously unrecognized member of the system of normal human plasma glycoproteins. Like certain other glycoproteins, its plasma concentration frequently increases in patients with neoplastic disease, chronic inflammatory disease, or tuberculosis and after surgery. Because molecular weight is 29,000, increased plasma concentration readily causes its appearance in the urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204683"} {"pmid": "4204686", "title": "Fine structure of the newt parathyroid gland after EDTA administration: mechanism of formation and extrusion of secretory granules.", "content": "Fine structure of the newt parathyroid gland after EDTA administration: mechanism of formation and extrusion of secretory granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204686"} {"pmid": "4204684", "title": "Design and evaluation by nitrogen balance and blood aminograms of an amino acid mixture for total parenteral nutrition of adults with gastrointestinal disease.", "content": "Design and evaluation by nitrogen balance and blood aminograms of an amino acid mixture for total parenteral nutrition of adults with gastrointestinal disease. This study was undertaken to assess the efficacy of an amino acid mixture formulated for intravenous use from estimates of requirements for essential amino acids of human adults, and from data previously derived from a study using casein hydrolysate as the amino acid source. This mixture contained 39.4% essential amino acids, with glycine, alanine, arginine, histidine, and proline selected to supply the nonessential nitrogen. Nitrogen balance and blood aminograms were measured in six adult patients with gastrointestinal disease, fed intravenously for 1 wk at each of three levels of amino acid intake, while all other nutrients were constant and adequate in relation to body weight. Four of the patients were then fed 1.0 g/kg of egg or meat protein orally for 1 wk at the end of the 3 wk study, while all nutrients other than the amino acids were fed intravenously. Average nitrogen balances of -0.8, 0.5, and 2.2 g/day were observed when the amounts of amino acids infused were 0.25, 0.5, and 1.0 g/kg, respectively. Fasting levels of threonine, glycine, cystine, methionine, isoleucine, tryptophan, and arginine, but not of the other amino acids, increased with the increment in input, although the levels were generally lower than normal. The increase in blood concentration observed during infusion was similar for each of the essential amino acids, indicating that the supply of each of the amino acids was much better balanced for utilization than casein hydrolysate. However the blood aminograms did suggest that some changes in composition of the mixture for the malnourished adult were desirable, such that the amino acid mixture resembled that needed by the normal growing child. Nitrogen balance in the four patients fed orally with high-quality protein averaged 2.0 g/day, showing that an amino acid mixture given intravenously, provided it is well-balanced, can be utilized as efficiently as protein given orally. It is concluded that the prediction of oral requirements for amino acids should be combined with observations on changes in blood aminograms during infusion over a range of amino acid input in the development of amino acid mixtures for intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204684"} {"pmid": "4204687", "title": "Letter: Crystal-like structure in the sporulating cells of Bacillus subtilis 168.", "content": "Letter: Crystal-like structure in the sporulating cells of Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204687"} {"pmid": "4204678", "title": "Cancer mortality in Blacks.", "content": "Cancer mortality in Blacks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204678"} {"pmid": "4204688", "title": "Thyroxine-binding proteins in sheep serum.", "content": "Thyroxine-binding proteins in sheep serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204688"} {"pmid": "4204676", "title": "Systematic head and neck examination.", "content": "Systematic head and neck examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204676"} {"pmid": "4204689", "title": "Effect of thyroidectomy on the concentration of plasma thyroxine-binding proteins in sheep.", "content": "Effect of thyroidectomy on the concentration of plasma thyroxine-binding proteins in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204689"} {"pmid": "4204690", "title": "Evaluation of nitroglycerin ointment.", "content": "Evaluation of nitroglycerin ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204690"} {"pmid": "4204677", "title": "Emotional crises and cancer.", "content": "Emotional crises and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204677"} {"pmid": "4204691", "title": "The simultaneous effect of protein-calorie malnutrition on weight and height velocity.", "content": "The simultaneous effect of protein-calorie malnutrition on weight and height velocity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204691"} {"pmid": "4204693", "title": "Minicells of Bacillus subtilis: a new bacteriophage-blocking agent.", "content": "Minicells of Bacillus subtilis: a new bacteriophage-blocking agent. Bacteriophage SP01, SP17, and phi29 rapidly absorb irreversibly to minicells of Bacillus subtilis but do not produce a lytic cycle in minicells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204693"} {"pmid": "4204692", "title": "Activation of a latent measles virus infection in hamster cells.", "content": "Activation of a latent measles virus infection in hamster cells. The characteristics of infectious measles virus released from latently infected hamster embryo fibroblast cells are described. Low levels of virus were released spontaneously when the cultures were incubated at 37 C; this phenomenon was observed 19 passages after the cells had been exposed to the virus and has continued through cell passage 45. The virus yield could be significantly increased by cocultivation of the hamster cells with BSC-1 cells or incubation of the latently infected cells at 33.5 C rather than at 37 C. Measles virus released after cocultivation demonstrated increased cytopathology in cell culture and reduced temperature sensitivity when compared to the virus released at 33.5 C. After cell passage 45, there was an increase in spontaneous release of virus. However, the viruses recovered by cocultivation or temperature release after cell passage 45 were nearly identical. These observations suggest a possible mechanism for measles virus activation in cells latently infected with this virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204692"} {"pmid": "4204679", "title": "Classics in oncology. Matthew Baillie (1761-1823).", "content": "Classics in oncology. Matthew Baillie (1761-1823).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204679"} {"pmid": "4204694", "title": "Increased nerve-growth-stimulating activity in disseminated neurofibromatosis.", "content": "Increased nerve-growth-stimulating activity in disseminated neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204694"} {"pmid": "4204695", "title": "Editorial: Nerve growth in neurofibromatosis.", "content": "Editorial: Nerve growth in neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204695"} {"pmid": "4204696", "title": "Letter: Enhancement of enzymatic activity in Fabry's disease.", "content": "Letter: Enhancement of enzymatic activity in Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204696"} {"pmid": "4204697", "title": "Letter: Priapism after phenoxybenzamine in a patient with Fabry's disease.", "content": "Letter: Priapism after phenoxybenzamine in a patient with Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204697"} {"pmid": "4204698", "title": "Letter: Cost of health services in Sweden and England.", "content": "Letter: Cost of health services in Sweden and England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204698"} {"pmid": "4204699", "title": "Endotoxic shock.", "content": "Endotoxic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204699"} {"pmid": "4204700", "title": "Endocavity irradiation of early rectal cancers for cure: a series of 123 cases.", "content": "Endocavity irradiation of early rectal cancers for cure: a series of 123 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204700"} {"pmid": "4204701", "title": "Preoperative megavoltage radiotherapy for advanced carcinoma of the rectum.", "content": "Preoperative megavoltage radiotherapy for advanced carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204701"} {"pmid": "4204706", "title": "Postgraduate education and training in public health. Report a WHO Expert Committee.", "content": "Postgraduate education and training in public health. Report a WHO Expert Committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204706"} {"pmid": "4204707", "title": "Environmental and health monitoring in occupational health. Report of a WHO Expert Committee.", "content": "Environmental and health monitoring in occupational health. Report of a WHO Expert Committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204707"} {"pmid": "4204708", "title": "Bioavailability of drugs: principles and problems. Report of a WHO Scientific Group.", "content": "Bioavailability of drugs: principles and problems. Report of a WHO Scientific Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204708"} {"pmid": "4204709", "title": "Malaria control in countries where time-limited eradication is impracticable at present. Report of a WHO Interregional Conference.", "content": "Malaria control in countries where time-limited eradication is impracticable at present. Report of a WHO Interregional Conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204709"} {"pmid": "4204711", "title": "Gold levels in serum during the treatment of rheumatoid arthritis with gold sodium thiomalate.", "content": "Gold levels in serum during the treatment of rheumatoid arthritis with gold sodium thiomalate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204711"} {"pmid": "4204712", "title": "Protein selectivity in the assessment of patients with proteinuria.", "content": "Protein selectivity in the assessment of patients with proteinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204712"} {"pmid": "4204713", "title": "Aetiological factors in ovine posthitis.", "content": "Aetiological factors in ovine posthitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204713"} {"pmid": "4204714", "title": "Degradation of hyaluronic acid by baboon sex-skin tissue.", "content": "Degradation of hyaluronic acid by baboon sex-skin tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204714"} {"pmid": "4204715", "title": "Effect of sulfonylureas on the secretion of pancreatic immunoreactive glucagon and enteric glucagon-like immunoreactivity.", "content": "Effect of sulfonylureas on the secretion of pancreatic immunoreactive glucagon and enteric glucagon-like immunoreactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204715"} {"pmid": "4204716", "title": "A comparative evaluation of the ultrastructural changes following induced cerebral infarction in the squirrel monkey and baboon.", "content": "A comparative evaluation of the ultrastructural changes following induced cerebral infarction in the squirrel monkey and baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204716"} {"pmid": "4204718", "title": "Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 1. Kinetics of formation of the polypeptide components of the crystal protein in vivo.", "content": "Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 1. Kinetics of formation of the polypeptide components of the crystal protein in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204718"} {"pmid": "4204717", "title": "Occurrence of 2-amino-2-deoxy-hexuronic acids as constituents of Vibrio parahaemolyticus K15 antigen.", "content": "Occurrence of 2-amino-2-deoxy-hexuronic acids as constituents of Vibrio parahaemolyticus K15 antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204717"} {"pmid": "4204719", "title": "Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 2. On the relation of transcriptional and translational events in the growth cycle.", "content": "Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 2. On the relation of transcriptional and translational events in the growth cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204719"} {"pmid": "4204720", "title": "Purification and properties of an iodide peroxidase from submaxillary gland of goat.", "content": "Purification and properties of an iodide peroxidase from submaxillary gland of goat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204720"} {"pmid": "4204721", "title": "Evaluation of alclofenac treatment regimes in man.", "content": "Evaluation of alclofenac treatment regimes in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204721"} {"pmid": "4204722", "title": "Virulence of multidrugresistant Mycobacterium tuberculosis.", "content": "Virulence of multidrugresistant Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204722"} {"pmid": "4204724", "title": "General and specific effects of modifiers of mutant expression.", "content": "General and specific effects of modifiers of mutant expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204724"} {"pmid": "4204726", "title": "Growth hormone secretion in protein-calorie malnutrition.", "content": "Growth hormone secretion in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204726"} {"pmid": "4204727", "title": "Response of rhesus monkeys to LRH throughout the ovarian cycle.", "content": "Response of rhesus monkeys to LRH throughout the ovarian cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204727"} {"pmid": "4204728", "title": "Characterization of a human acute phase protein found in association with rubella virus infection.", "content": "Characterization of a human acute phase protein found in association with rubella virus infection. A precipitating antigen, rho, was first detected in the blood of persons with rubella and in rubella virus-infected cell culture fluids (1). Partially purified antigens from both sources were examined and shown to have similar properties, although antigen from serum sedimented more heterogeneously, with estimated coefficients from 15 to 21 S, while that from culture fluids sedimented in the 11-14 S region. In each case, antigen was located in the beta-1 zone after electrophoresis in agarose, and at a density of 1.305 g/ml after centrifugation in CsCl. Stability characteristics were typical of protein antigens. Immunofluorescent microscopy revealed that rubella virus induced the appearance of rho antigen scattered throughout the cytoplasm of infected cells. When cells containing antigen were exposed for 24 h to 5 microg/ml actinomycin D rho was no longer detectable, indicating the probable cellular origin of the antigen. Also, titers in medium of infected cultures showed a reduction after actinomycin treatment, but levels of the virus-specified antigen, iota, were relatively unaffected. Rho appears to be a protein common to man and many animals. In vitro, it was induced by rubella virus and by adenovirus. In vivo, rho titers were shown to be elevated after rubella virus infection and, to a lesser extent, after infection with certain other viruses. High titers were also demonstrated in women late in pregnancy and in patients with rheumatoid arthritis. In man and the chimpanzee, the appearance and decline of rho in the blood after rubella virus infection were temporally similar to the patterns of CRP, although rho seemed to be a more sensitive indicator of infection. The data presented indicate that rho is a newly recognized acute phase protein inducible by certain virus infections and by other unidentified stimuli present prominently in pregnancy and rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204728"} {"pmid": "4204730", "title": "New, third class of amyloid fibril protein.", "content": "New, third class of amyloid fibril protein. An unusual protein AR was isolated from the amyloid fibril preparation derived from a patient with primary amyloidosis. Protein AR was unique in its antigenicity, and revealed no structural identity with any known amyloid proteins or with immunoglobulin chains or fragments. Thus a new third class of amyloid fibril proteins besides the immunoglobulin light-chain variable region fragments and the nonimmunoglobulin protein AS, has been characterized. A component antigenically related to protein AR was found in the serum of the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204730"} {"pmid": "4204731", "title": "Evaluation of thyrotropin-releasing hormone as a potential antidepressant agent in the conscious dog.", "content": "Evaluation of thyrotropin-releasing hormone as a potential antidepressant agent in the conscious dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204731"} {"pmid": "4204732", "title": "Dental defects in hamsters infected with minute virus of mice.", "content": "Dental defects in hamsters infected with minute virus of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204732"} {"pmid": "4204729", "title": "Localization of free and bound secretory component in human intestinal epithelial cells. A model for the assembly of secretory IgA.", "content": "Localization of free and bound secretory component in human intestinal epithelial cells. A model for the assembly of secretory IgA. Antibody reagents were made specific for each of the two forms of human SC, FSC and BSC, which is an integral part of the sIgA molecule. With the fluorescent antibody method the cytological and histological localization of FSC, BSC, and alpha-chains has been studied in various human mucous membranes. SC was present in columnar epithelial cells of the intestines and in the cells of serous acini of bronchial and salivary glands. In contrast, SC was not found in intestinal goblet cells or cells of mucous acini of bronchial and salivary glands. In the columnar epithelial cells of the small and large bowel, FSC was present most prominently in the Golgi zone, and much less prominently in the apical cytoplasm. On the other hand, BSC and alpha-chains were located only in the apical cytoplasm in an overlapping manner. The results favor a model in which sIgA is assembled inside epithelial cells from SC, which was synthesized in the same cell, and IgA, which entered the epithelial cell after synthesis in and secretion by a plasma cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204729"} {"pmid": "4204733", "title": "Dental pulp regeneration aided by blood and blood substitutes after experimentally induced periapical infection.", "content": "Dental pulp regeneration aided by blood and blood substitutes after experimentally induced periapical infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204733"} {"pmid": "4204734", "title": "Analysis of histologic criteria commonly used in pulp studies.", "content": "Analysis of histologic criteria commonly used in pulp studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204734"} {"pmid": "4204739", "title": "Antigenicity and stilbamidine resistance in Trypanosoma brucei rhodesiense.", "content": "Antigenicity and stilbamidine resistance in Trypanosoma brucei rhodesiense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204739"} {"pmid": "4204740", "title": "Letter: Serology and antimicrobial sensitivity of meningococci isolated in Uganda.", "content": "Letter: Serology and antimicrobial sensitivity of meningococci isolated in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204740"} {"pmid": "4204742", "title": "Letter: Acquired resistance to Schistosoma haematobium in the baboon (Papio anubis).", "content": "Letter: Acquired resistance to Schistosoma haematobium in the baboon (Papio anubis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204742"} {"pmid": "4204741", "title": "Enzyme variants in primate malaria parasites.", "content": "Enzyme variants in primate malaria parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204741"} {"pmid": "4204743", "title": "Letter: Identification of guinea-worm species.", "content": "Letter: Identification of guinea-worm species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204743"} {"pmid": "4204744", "title": "Cytotoxic substances in sera from P. knowlesi-infected rhesus monkeys.", "content": "Cytotoxic substances in sera from P. knowlesi-infected rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204744"} {"pmid": "4204745", "title": "6-Phosphogluconate dehydrogenase activity in malaria-infected erythrocytes.", "content": "6-Phosphogluconate dehydrogenase activity in malaria-infected erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204745"} {"pmid": "4204746", "title": "Eperythrozoon and Haemobartonella in primates.", "content": "Eperythrozoon and Haemobartonella in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204746"} {"pmid": "4204747", "title": "Acquired resistance to Schistosoma haematobium in the baboon.", "content": "Acquired resistance to Schistosoma haematobium in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204747"} {"pmid": "4204748", "title": "Malaria parasites in Presbytis aygula. New host record of Hepatocystis semnopitheci.", "content": "Malaria parasites in Presbytis aygula. New host record of Hepatocystis semnopitheci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204748"} {"pmid": "4204749", "title": "Malaria parasites in Callosciurus nigrovittatus.", "content": "Malaria parasites in Callosciurus nigrovittatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204749"} {"pmid": "4204750", "title": "Polychromophilus species in insectivorous bats.", "content": "Polychromophilus species in insectivorous bats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204750"} {"pmid": "4204751", "title": "Hymenopteran egg-parasite of triatomine bugs.", "content": "Hymenopteran egg-parasite of triatomine bugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204751"} {"pmid": "4204752", "title": "Malaria parasites of domestic fowl in Sabah.", "content": "Malaria parasites of domestic fowl in Sabah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204752"} {"pmid": "4204753", "title": "A multi-species malaria antigen for use in the indirect fluorescent antibody test.", "content": "A multi-species malaria antigen for use in the indirect fluorescent antibody test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204753"} {"pmid": "4204754", "title": "Two types of schizonts of Hepatocystis sp., a parasite of insectivorous bats in the Congo-Brazzaville.", "content": "Two types of schizonts of Hepatocystis sp., a parasite of insectivorous bats in the Congo-Brazzaville.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204754"} {"pmid": "4204756", "title": "Vesicoureteral reflux in adults. A twelve-year study of 122 patients.", "content": "Vesicoureteral reflux in adults. A twelve-year study of 122 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204756"} {"pmid": "4204755", "title": "Chemotherapy for bladder cancer.", "content": "Chemotherapy for bladder cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204755"} {"pmid": "4204762", "title": "The effects of anesthetics on permeability to water of the inactivated toad bladder.", "content": "The effects of anesthetics on permeability to water of the inactivated toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204762"} {"pmid": "4204764", "title": "Benzodiazepines in the treatment of epilepsy. A review.", "content": "Benzodiazepines in the treatment of epilepsy. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204764"} {"pmid": "4204766", "title": "Health trends in three Asian countries--Ceylon, Malaysia and Singapore.", "content": "Health trends in three Asian countries--Ceylon, Malaysia and Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204766"} {"pmid": "4204767", "title": "Fine structure and function of ocular tissues. The ciliary body.", "content": "Fine structure and function of ocular tissues. The ciliary body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204767"} {"pmid": "4204768", "title": "Fine structure and function of ocular tissues. The vitreous.", "content": "Fine structure and function of ocular tissues. The vitreous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204768"} {"pmid": "4204769", "title": "Fine structure and function of ocular tissues. Extraocular muscle.", "content": "Fine structure and function of ocular tissues. Extraocular muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204769"} {"pmid": "4204770", "title": "Specialized techniques in electron microscopy.", "content": "Specialized techniques in electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204770"} {"pmid": "4204771", "title": "An ergot alkaloid preparation (Hydergine) in the treatment of presenile brain atrophy (Alzheimer's disease): case report.", "content": "An ergot alkaloid preparation (Hydergine) in the treatment of presenile brain atrophy (Alzheimer's disease): case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204771"} {"pmid": "4204772", "title": "Patient non-compliance within the context of seeking medical care for arthritis.", "content": "Patient non-compliance within the context of seeking medical care for arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204772"} {"pmid": "4204774", "title": "Long-term consequences of vestibular ablation by laser in a monkey.", "content": "Long-term consequences of vestibular ablation by laser in a monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204774"} {"pmid": "4204773", "title": "About quantitative studies on the cerebral cortex.", "content": "About quantitative studies on the cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204773"} {"pmid": "4204775", "title": "Hydergine for cerebral arteriosclerosis.", "content": "Hydergine for cerebral arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204775"} {"pmid": "4204778", "title": "Proceedings: Penicillins: use of an animal model to predict bioavailability.", "content": "Proceedings: Penicillins: use of an animal model to predict bioavailability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204778"} {"pmid": "4204779", "title": "Estimation of molecular weights of rat liver ribosomal proteins.", "content": "Estimation of molecular weights of rat liver ribosomal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204779"} {"pmid": "4204780", "title": "The proteins of rapidly labelled polysomal mRNP of rat liver.", "content": "The proteins of rapidly labelled polysomal mRNP of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204780"} {"pmid": "4204781", "title": "Study of the in-vitro sensitivity of meningococci and its implications in prophylaxis.", "content": "Study of the in-vitro sensitivity of meningococci and its implications in prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204781"} {"pmid": "4204783", "title": "Studies on serum antigens in carp.", "content": "Studies on serum antigens in carp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204783"} {"pmid": "4204784", "title": "Effects of genetic background on the competition between the asc and FM6 chromosomes of Drosophila melanogaster.", "content": "Effects of genetic background on the competition between the asc and FM6 chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204784"} {"pmid": "4204785", "title": "Flavor aversions produced by contingent drug injection: relative effectiveness of apomorphine, emetine, and lithium.", "content": "Flavor aversions produced by contingent drug injection: relative effectiveness of apomorphine, emetine, and lithium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204785"} {"pmid": "4204786", "title": "Preservation of 23-S chloroplast RNA as a single chain of nucleotides.", "content": "Preservation of 23-S chloroplast RNA as a single chain of nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204786"} {"pmid": "4204788", "title": "Neuronal alteration and reinnervation following axonal regeneration and sprouting in mammalian spinal cord.", "content": "Neuronal alteration and reinnervation following axonal regeneration and sprouting in mammalian spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204788"} {"pmid": "4204787", "title": "Morphological plasticity of central adrenergic neurons.", "content": "Morphological plasticity of central adrenergic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204787"} {"pmid": "4204789", "title": "Anatomical and physiological correlates of plasticity in the central nervous system.", "content": "Anatomical and physiological correlates of plasticity in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204789"} {"pmid": "4204777", "title": "The alteration of aversive thresholds with cholinergic and adrenergic agents.", "content": "The alteration of aversive thresholds with cholinergic and adrenergic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204777"} {"pmid": "4204790", "title": "Vitamin E in angina pectoris.", "content": "Vitamin E in angina pectoris. The claim that the symptoms of angina pectoris can usually be relieved by large doses of vitamin E has been reinvestigated by means of a randomized double-blind trial. The trial lasted nine weeks and consisted of two parts. One part was conducted as a regular double-blind trial involving 40 patients, half of whom received 3200 IU of vitamin E daily, while an equal number received an indistinguishable placebo. The second part of the trial involved 15 patients who were already taking a regular daily dose of between 400 and 2400 IU of vitamin E. Eight patients were assigned the same (or a larger) dose of vitamin E, while seven received placebo. Neither part of the trial yielded statistically convincing evidence that vitamin E is of value in the treatment of angina, but a small beneficial effect could not be ruled out. Taken in conjunction with the positive (but statistically non-significant) results obtained in the only other double-blind trial of vitamin E ever carried out on angina, and the encouraging results reported by other investigators in the treatment of intermittent claudication, it is suggested that further double-blind trials are justified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204790"} {"pmid": "4204791", "title": "Estimation of serum and red cell folate by a simple radiometric technique.", "content": "Estimation of serum and red cell folate by a simple radiometric technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204791"} {"pmid": "4204792", "title": "Computer reduction and analysis of neurophysiological data with special emphasis on evoked potential frequency analysis.", "content": "Computer reduction and analysis of neurophysiological data with special emphasis on evoked potential frequency analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204792"} {"pmid": "4204776", "title": "Effects of scopolamine, amphetamine and benzodiazepines on conditioned suppression.", "content": "Effects of scopolamine, amphetamine and benzodiazepines on conditioned suppression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204776"} {"pmid": "4204793", "title": "Stereoscopic form disappearance in temporal lobe dysfunction.", "content": "Stereoscopic form disappearance in temporal lobe dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204793"} {"pmid": "4204796", "title": "Ionophore A23187, calcium and contractility in frog eggs.", "content": "Ionophore A23187, calcium and contractility in frog eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204796"} {"pmid": "4204797", "title": "Photoreactivation of excystment delay in Colpoda, induced by far ultraviolet radiation.", "content": "Photoreactivation of excystment delay in Colpoda, induced by far ultraviolet radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204797"} {"pmid": "4204798", "title": "What is a case of tuberculosis? The tuberculosis case spectrum in eight countries evaluated from 1235 case histories and roentgenograms.", "content": "What is a case of tuberculosis? The tuberculosis case spectrum in eight countries evaluated from 1235 case histories and roentgenograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204798"} {"pmid": "4204799", "title": "Isoniazid chemoprophylaxis of latent primary tuberculosis: in five trial centres in France from 1959 to 1969.", "content": "Isoniazid chemoprophylaxis of latent primary tuberculosis: in five trial centres in France from 1959 to 1969.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204799"} {"pmid": "4204801", "title": "The effect of different preparative methods on nuclear shape in the surface epithelium of the hamster ovary.", "content": "The effect of different preparative methods on nuclear shape in the surface epithelium of the hamster ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204801"} {"pmid": "4204800", "title": "Cellular changes in the lateral geniculate nucleus of infant monkeys after suture of the eyelids.", "content": "Cellular changes in the lateral geniculate nucleus of infant monkeys after suture of the eyelids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204800"} {"pmid": "4204802", "title": "Evaluation of an antiasthmatic agent cromolyn sodium (Aarane, Intal).", "content": "Evaluation of an antiasthmatic agent cromolyn sodium (Aarane, Intal).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204802"} {"pmid": "4204803", "title": "Evaluation of post-episiorrhaphy pain: polyglycolic acid vs catgut sutures.", "content": "Evaluation of post-episiorrhaphy pain: polyglycolic acid vs catgut sutures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204803"} {"pmid": "4204804", "title": "Brenner tumor.", "content": "Brenner tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204804"} {"pmid": "4204805", "title": "Intubation: the simple approach to bleeding from the mesenteric small bowel.", "content": "Intubation: the simple approach to bleeding from the mesenteric small bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204805"} {"pmid": "4204806", "title": "Epidemiology of heroin dependency among soldiers in Vietnam.", "content": "Epidemiology of heroin dependency among soldiers in Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204806"} {"pmid": "4204807", "title": "Opiate addiction and military psychiatry to the end of World War II.", "content": "Opiate addiction and military psychiatry to the end of World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204807"} {"pmid": "4204808", "title": "Nursing practice in a medical research setting.", "content": "Nursing practice in a medical research setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204808"} {"pmid": "4204809", "title": "Dental emergencies occurring among Navy-Marine personnel serving in Vietnam.", "content": "Dental emergencies occurring among Navy-Marine personnel serving in Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204809"} {"pmid": "4204810", "title": "Frequency of hepatitis-associated antigen among drug users in the Naval service.", "content": "Frequency of hepatitis-associated antigen among drug users in the Naval service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204810"} {"pmid": "4204811", "title": "Optic chiasmatic arachnoiditis: improvement of rapidly failing vision following surgical lysis of chiasmatic adhesions and postoperative steroid therapy.", "content": "Optic chiasmatic arachnoiditis: improvement of rapidly failing vision following surgical lysis of chiasmatic adhesions and postoperative steroid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204811"} {"pmid": "4204812", "title": "Injuries to divers by marine animals: a simplified approach to recognition and management.", "content": "Injuries to divers by marine animals: a simplified approach to recognition and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204812"} {"pmid": "4204813", "title": "Editorial: Communicating clinical research in nursing.", "content": "Editorial: Communicating clinical research in nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204813"} {"pmid": "4204814", "title": "Immunoprophylaxis of meningococcal infection.", "content": "Immunoprophylaxis of meningococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204814"} {"pmid": "4204815", "title": "Psychiatric perspectives of the Vietnam veteran.", "content": "Psychiatric perspectives of the Vietnam veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204815"} {"pmid": "4204816", "title": "Oral lymphogranuloma venereum and cervical lymphadenopathy. Case report.", "content": "Oral lymphogranuloma venereum and cervical lymphadenopathy. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204816"} {"pmid": "4204817", "title": "Transformation of an R-factor from Pseudomonas aeruginosa into Rhizobium trifolii.", "content": "Transformation of an R-factor from Pseudomonas aeruginosa into Rhizobium trifolii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204817"} {"pmid": "4204822", "title": "A comparison of direct and diluted sputum culture results.", "content": "A comparison of direct and diluted sputum culture results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204822"} {"pmid": "4204827", "title": "Experimental allergic encephalomyelitis in hamsters.", "content": "Experimental allergic encephalomyelitis in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204827"} {"pmid": "4204828", "title": "Species specificity in the TSH response to the administration of L-dopa.", "content": "Species specificity in the TSH response to the administration of L-dopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204828"} {"pmid": "4204830", "title": "The neural basis of visually guided behavior.", "content": "The neural basis of visually guided behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204830"} {"pmid": "4204829", "title": "Pregnancy-associated serum antigens in the rat and mouse.", "content": "Pregnancy-associated serum antigens in the rat and mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204829"} {"pmid": "4204831", "title": "Platelet aggregation by large molecules.", "content": "Platelet aggregation by large molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204831"} {"pmid": "4204833", "title": "Relationship of the localization of autosomal lethal mutations to their concentrations in natural populations of Drosophila melanogaster.", "content": "Relationship of the localization of autosomal lethal mutations to their concentrations in natural populations of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204833"} {"pmid": "4204832", "title": "Studies on reaction between thrombin and actin.", "content": "Studies on reaction between thrombin and actin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204832"} {"pmid": "4204834", "title": "Repair of UV-damaged DNA by competent and incompetent Bacillus subtilis cells.", "content": "Repair of UV-damaged DNA by competent and incompetent Bacillus subtilis cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204834"} {"pmid": "4204835", "title": "Urethral diverticulum in adult female. Clinical aspects, operative procedure, and pathology.", "content": "Urethral diverticulum in adult female. Clinical aspects, operative procedure, and pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204835"} {"pmid": "4204836", "title": "Bladder diverticulectomy. With aid of inflated Foley balloon catheter.", "content": "Bladder diverticulectomy. With aid of inflated Foley balloon catheter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204836"} {"pmid": "4204837", "title": "Psychophysical studies of monkey vision. I. Macaque luminosity and color vision tests.", "content": "Psychophysical studies of monkey vision. I. Macaque luminosity and color vision tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204837"} {"pmid": "4204838", "title": "Psychophysical studies of monkey vision. II. Squirrel monkey wavelength and saturation discrimination.", "content": "Psychophysical studies of monkey vision. II. Squirrel monkey wavelength and saturation discrimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204838"} {"pmid": "4204839", "title": "Psychophysical studies of monkey vision. 3. Spatial luminance contrast sensitivity tests of macaque and human observers.", "content": "Psychophysical studies of monkey vision. 3. Spatial luminance contrast sensitivity tests of macaque and human observers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204839"} {"pmid": "4204841", "title": "Fate of exogenous DNA in Neisseria meningitidis. I. Preparation of 15N-donor DNA and its fate in transformation.", "content": "Fate of exogenous DNA in Neisseria meningitidis. I. Preparation of 15N-donor DNA and its fate in transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204841"} {"pmid": "4204842", "title": "Fate of exogenous DNA in Neisseria meningitidis. 2. Influence of acriflavin and ethidium bromide and significance of genetic competence on the fate of 15N DNA.", "content": "Fate of exogenous DNA in Neisseria meningitidis. 2. Influence of acriflavin and ethidium bromide and significance of genetic competence on the fate of 15N DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204842"} {"pmid": "4204843", "title": "Identification and quantitation of precipitins against Pseudomonas aeruginosa in patients with cystic fibrosis by means of crossed immunoelectrophoresis with intermediate gel.", "content": "Identification and quantitation of precipitins against Pseudomonas aeruginosa in patients with cystic fibrosis by means of crossed immunoelectrophoresis with intermediate gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204843"} {"pmid": "4204844", "title": "Wall teichoic acids in animal Staphylococcus aureus strains determined by precipitation.", "content": "Wall teichoic acids in animal Staphylococcus aureus strains determined by precipitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204844"} {"pmid": "4204845", "title": "An easy way of improving the flatness of the radiation from a linear accelerator.", "content": "An easy way of improving the flatness of the radiation from a linear accelerator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204845"} {"pmid": "4204846", "title": "Origin of radiation released serotonin in rabbits and mice.", "content": "Origin of radiation released serotonin in rabbits and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204846"} {"pmid": "4204847", "title": "Plasma and leukocyte ascorbic acid levels in the elderly.", "content": "Plasma and leukocyte ascorbic acid levels in the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204847"} {"pmid": "4204848", "title": "Comparison of fibrin hydrolysates and crystalline amino acid solutions in parenteral nutrition.", "content": "Comparison of fibrin hydrolysates and crystalline amino acid solutions in parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204848"} {"pmid": "4204849", "title": "The matabolic fuel regulatory system: implications for protein-sparing therapies during caloric deprivation and disease.", "content": "The matabolic fuel regulatory system: implications for protein-sparing therapies during caloric deprivation and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204849"} {"pmid": "4204850", "title": "Nutritional hazards of food taboos and preferences in Mid-West Nigeria.", "content": "Nutritional hazards of food taboos and preferences in Mid-West Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204850"} {"pmid": "4204851", "title": "Opponent processes as a model of neural organization.", "content": "Opponent processes as a model of neural organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204851"} {"pmid": "4204852", "title": "Experimental carbon monoxide encephalopathy in the primate I. Physiologic and metabolic aspects.", "content": "Experimental carbon monoxide encephalopathy in the primate I. Physiologic and metabolic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204852"} {"pmid": "4204853", "title": "Experimental carbon monoxide encephalopathy in the primate. II. Clinical aspects, neuropathology, and physiologic correlation.", "content": "Experimental carbon monoxide encephalopathy in the primate. II. Clinical aspects, neuropathology, and physiologic correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204853"} {"pmid": "4204854", "title": "SSPE virus infections in suckling hamsters. Modification by intracerebral administration of poly I-C.", "content": "SSPE virus infections in suckling hamsters. Modification by intracerebral administration of poly I-C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204854"} {"pmid": "4204855", "title": "Pulmonary alveolar proteinosis and Nocardia brain abscess. Report of a case.", "content": "Pulmonary alveolar proteinosis and Nocardia brain abscess. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204855"} {"pmid": "4204856", "title": "Studies of a transplantable canine sarcoma.", "content": "Studies of a transplantable canine sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204856"} {"pmid": "4204857", "title": "Oncorna type virus particles in a tumor of a rhesus monkey.", "content": "Oncorna type virus particles in a tumor of a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204857"} {"pmid": "4204859", "title": "Effects of myelopoietic factors isolated from rat serum on murine myelogenous leukemia.", "content": "Effects of myelopoietic factors isolated from rat serum on murine myelogenous leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204859"} {"pmid": "4204858", "title": "Gross virus leukemia in the rat: kinetics of infection and immunity.", "content": "Gross virus leukemia in the rat: kinetics of infection and immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204858"} {"pmid": "4204881", "title": "Measurement of resistance to air flow in the nose in a trial with sodium cromoglycate (BP)solution in allergen-induced nasal stenosis.", "content": "Measurement of resistance to air flow in the nose in a trial with sodium cromoglycate (BP)solution in allergen-induced nasal stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204881"} {"pmid": "4204880", "title": "The localization of \"ordinary\" sex-linked genes in section 20 of the polytene X chromosome of Drosophila melanogaster.", "content": "The localization of \"ordinary\" sex-linked genes in section 20 of the polytene X chromosome of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204880"} {"pmid": "4204882", "title": "Serum IgE levels and the use of sodium cromoglycate (BP) in hay fever: a study of forty-six patients from a single general practice.", "content": "Serum IgE levels and the use of sodium cromoglycate (BP) in hay fever: a study of forty-six patients from a single general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204882"} {"pmid": "4204883", "title": "Trace-element analysis in hair: an evaluation.", "content": "Trace-element analysis in hair: an evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204883"} {"pmid": "4204884", "title": "Rapid ultramicro direct determination of erythrocyte lead concentration by atomic absorption spectrophotometry, with use of a graphite-tube furnace.", "content": "Rapid ultramicro direct determination of erythrocyte lead concentration by atomic absorption spectrophotometry, with use of a graphite-tube furnace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204884"} {"pmid": "4204887", "title": "Notes on the ecology and behaviour of the Angola colobus (Colobus angolensis P. L. Sclater 1860) in N.E. Tanzania.", "content": "Notes on the ecology and behaviour of the Angola colobus (Colobus angolensis P. L. Sclater 1860) in N.E. Tanzania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204887"} {"pmid": "4204888", "title": "Wrist mechanism and locomotor behavior of Dryopithecus (Proconsul) africanus.", "content": "Wrist mechanism and locomotor behavior of Dryopithecus (Proconsul) africanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204888"} {"pmid": "4204889", "title": "Interactions between adult female and infant howling monkeys (Alouatta palliata).", "content": "Interactions between adult female and infant howling monkeys (Alouatta palliata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204889"} {"pmid": "4204891", "title": "Condensation of chromosomes during mitotic prophase. Whole mount electron microscopy of cerebral ganglion cells of Drosophila.", "content": "Condensation of chromosomes during mitotic prophase. Whole mount electron microscopy of cerebral ganglion cells of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204891"} {"pmid": "4204890", "title": "Quality and intensity of sugar solutions as determinants of ingestion by the rhesus monkey (Macaca mulatta).", "content": "Quality and intensity of sugar solutions as determinants of ingestion by the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204890"} {"pmid": "4204892", "title": "Tricomplex, a new type of autosome complement in Drosophila melanogaster.", "content": "Tricomplex, a new type of autosome complement in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204892"} {"pmid": "4204893", "title": "Heritability of recombination frequency. Observations on statistical complications and report on small-scale tests in Drosophila.", "content": "Heritability of recombination frequency. Observations on statistical complications and report on small-scale tests in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204893"} {"pmid": "4204894", "title": "Genetic load in a repeatedly irradiated Drosophila melanogaster population.", "content": "Genetic load in a repeatedly irradiated Drosophila melanogaster population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204894"} {"pmid": "4204895", "title": "Localization of genes controlling radioresistance in Drosophila melanogaster.", "content": "Localization of genes controlling radioresistance in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204895"} {"pmid": "4204896", "title": "Characterization of a meiotic control gene affecting recombination in Drosophila melanogaster.", "content": "Characterization of a meiotic control gene affecting recombination in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204896"} {"pmid": "4204897", "title": "The organization of chromosome fibrils in salivary-gland chromosomes of Drosophila melanogaster. Light microscopical observations of the effect of acetic acid.", "content": "The organization of chromosome fibrils in salivary-gland chromosomes of Drosophila melanogaster. Light microscopical observations of the effect of acetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204897"} {"pmid": "4204898", "title": "Oxidation of catechol in plants. II. Enzymic conversion of catechol to diphenylenedioxide 2,3-quinone in the leaves of Tecoma stans L.", "content": "Oxidation of catechol in plants. II. Enzymic conversion of catechol to diphenylenedioxide 2,3-quinone in the leaves of Tecoma stans L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204898"} {"pmid": "4204899", "title": "Purification and properties of hetero-beta-galactosidases from monkey liver and intestine.", "content": "Purification and properties of hetero-beta-galactosidases from monkey liver and intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204899"} {"pmid": "4204900", "title": "Neurofibromatosis--von Recklinghausen's disease in podiatric medicine. A review and report of two cases.", "content": "Neurofibromatosis--von Recklinghausen's disease in podiatric medicine. A review and report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204900"} {"pmid": "4204902", "title": "Documentation of auxotrophic mutation in blue-green bacteria: characterization of a tryptophan auxotroph in Agmenellum quadruplicatum.", "content": "Documentation of auxotrophic mutation in blue-green bacteria: characterization of a tryptophan auxotroph in Agmenellum quadruplicatum. A tryptophan-requiring auxotroph of Agmenellum quadruplicatum strain BG1, a species of blue-green bacteria, was isolated by means of a nitrosoguanidine-penicillin procedure. Its growth characteristics were determined, and the enzymological block was identified in the A activity of tryptophan synthetase. Starvation of the auxotroph for tryptophan resulted in the derepression of the synthesis of all five enzymes. The first four enzymes derepressed 2- to 3-fold, and tryptophan synthetase B derepressed 20-fold. In the parental prototroph, BG1, anthranilate synthetase was active in crude extracts with ammonia as the amino donor reactant, but not with glutamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204902"} {"pmid": "4204903", "title": "Nature of the elimination of the penicillinase plasmid from Staphylococcus aureus by surface-active agents.", "content": "Nature of the elimination of the penicillinase plasmid from Staphylococcus aureus by surface-active agents. Growth of Stapylococcus aureus in various ionic surface-active agents resulted in loss of the ability to produce penicillinase, whereas growth in nonionic surface-active agents had no effect on penicillinase production. The curing effect of various alkyl sulfates was found to be dependent upon the chain length. Curing by surface-active agents could be inhibited by magnesium. Reciprocal transduction experiments showed that curing by a surface-active agent was a property of the plasmid, not of the bacterial strain in which the plasmic resides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204903"} {"pmid": "4204904", "title": "Deoxyribonucleic acid distribution in Bacillus subtilis independent of cell elongation.", "content": "Deoxyribonucleic acid distribution in Bacillus subtilis independent of cell elongation. A temperature-sensitive DNA(-) mutant of Bacillus subtilis has been studied during the resumption of deoxyribonucleic acid (DNA) synthesis following a 45 to 30 C temperature shift. For several hours after return to 30 C, DNA synthesis proceeds although the cells fail to elongate appreciably. Autoradiographs of cell populations synthesizing DNA during the recovery period demonstrate that DNA can become distributed to previously unoccupied regions along the cell length. By varying the labeling regime, newly synthesized DNA as well as DNA present at the time of transfer from 45 to 30 C were followed independently. Measurements of the percent of cell length covered by grains ((3)H-thymine in DNA) demonstrate the progressive refilling of DNA-vacant cell regions by both newly synthesized and original DNA. These data indicate that cell surface growth is not an absolute requirement for segregation of bacterial DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204904"} {"pmid": "4204905", "title": "Initiation of Bacillus subtilis ribonucleic acid polymerase on deoxyribonucleic acid from bacteriophages 2C, phi 29, T4, and lambda.", "content": "Initiation of Bacillus subtilis ribonucleic acid polymerase on deoxyribonucleic acid from bacteriophages 2C, phi 29, T4, and lambda. Ribonucleic acid (RNA) synthesis primed by bacteriophage T4 or lambda deoxyribonucleic acid (DNA) with Bacillus subtilis RNA polymerase is severely inhibited by high ionic strength. In contrast, RNA synthesis on B. subtilis bacteriophage 2C, SPO1, or phi29 DNA is only moderately affected under similar conditions. The basis of this inhibition lies in the inability of the enzyme to initiate RNA chains with adenosine triphosphate or guanosine triphosphate (ATP, GTP). Binding to templates and the rate of catalysis in high salt after initiation do not seem to be affected. Incorporation of gamma-(32)P-ATP and GTP under a variety of conditions suggests that the specificity of B. subtilis RNA polymerase is different from that of the Escherichia coli enzyme and that it recognizes few promoters on T4 and lambda DNA. Although B. subtilis RNA polymerase initiates RNA chains primarily with ATP or GTP, initiations with pyrimidines can occur on DNA molecules in which hydroxymethyluracil replaces thymine. RNA synthesis on denatured DNA does not seem to be inhibited by high ionic strength, and on native T4 or lambda DNA the inhibition of initiation at constant ionic strength is inversely but not linearly proportional to the ionic radii of cations used to stabilize bihelical DNA to denaturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204905"} {"pmid": "4204906", "title": "Comparative immunological and enzymatic study of the tryptophan synthetase beta 2 subunit in the Enterobacteriaceae.", "content": "Comparative immunological and enzymatic study of the tryptophan synthetase beta 2 subunit in the Enterobacteriaceae. The beta(2) subunits of tryptophan synthetase, formula alpha(2)beta(2), from Escherichia coli, Shigella dysenteriae, Enterobacter aerogenes, Salmonella typhimurium, and Serratia marcescens were compared by three criteria. (i) alphabeta association constants for the various beta(2) subunits and E. coli alpha subunit varied between 3.6 x 10(8)m(-1) for E. coli and 0.33 x 10(8)m(-1) for S. marcescens; values for the other organisms were intermediate. (ii) Antiserum neutralization of the beta(2) subunit enzyme activity using anti-E. coli beta(2) serum showed significant cross-reaction among the organisms (E. coli, 1.0; S. dysenteriae, 0.98; S. typhimurium, 0.67; E. aerogenes, 0.61; S. marcescens, 0.42). (iii) Quantitative microcomplement fixation showed E. coli beta(2) and S. marcescens beta(2) subunits to have an index of dissimilarity of 1.8 while the other organisms had intermediate indexes. Similar complement fixation data were obtained with antisera from separate rabbits and from first course and boost sera. These findings suggest that the general surface structure and the respective alpha subunit binding site of the beta(2) subunits from these Enterobacteriaceae have been strongly conserved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204906"} {"pmid": "4204907", "title": "Genetically controlled removal of \"spore photoproduct\" from deoxyribonucleic acid of ultraviolet-irradiated Bacillus subtilis spores.", "content": "Genetically controlled removal of \"spore photoproduct\" from deoxyribonucleic acid of ultraviolet-irradiated Bacillus subtilis spores. Previous genetic analysis indicated that at least two genes determine the ultraviolet (UV) sensitivity of Bacillus subtilis spores. The present study shows that these genes independently control two distinguishable processes for removing UV-induced spore photoproduct (5-thyminyl-5,6-dihydrothymine, or TDHT) from spore deoxyribonucleic acid. The first, is a spore repair mechanism by which TDHT is removed rapidly without appearing in acid-soluble form. This mechanism, which is demonstrated in both UV-resistant and excision-deficient strains, operates to a certain extent during germination without requiring vegetative growth. The second, demonstrated in a mutant which lacks the first mechanism, removes TDHT relatively slowly and only if germinated spores are allowed to develop toward vegetative cells. The latter mechanism appears identical to excision-resynthesis repair, since the mutation abolishing it renders the irradiated vegetative cells incapable of removing cyclobutane-type pyrimidine dimers. Blocking either one of these mechanisms only slightly affects the UV sensitivity of spores, but blocking both prevents TDHT removal and gives high UV sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204907"} {"pmid": "4204909", "title": "Phenoloxidase activity in mycelia carrying modifier mutations that affect sporocarp development in Schizophyllum commune.", "content": "Phenoloxidase activity in mycelia carrying modifier mutations that affect sporocarp development in Schizophyllum commune. Phenoloxidase activity was studied in mycelia carrying mutations that affect sporocarp formation. The results suggest that phenoloxidase activity may be essential to, but is not sufficient for, the fruiting response in Schizophyllum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204909"} {"pmid": "4204908", "title": "Division site regulation in a temperature-sensitive mutant of Bacillus subtilis.", "content": "Division site regulation in a temperature-sensitive mutant of Bacillus subtilis. Division site location was measured in Bacillus subtilis clones grown from spores at 30 and 45 C. Regulation of division location is lost in mutant 168ts-151 at 45 C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204908"} {"pmid": "4204910", "title": "Time course of purine nucleoside phosphorylase occurrence in sporulation of Bacillus cereus.", "content": "Time course of purine nucleoside phosphorylase occurrence in sporulation of Bacillus cereus. Purine nucleoside phosphorylase (EC 2.4.2.1) from Bacillus cereus T was examined at hourly intervals during growth and sporulation. The enzyme has maximal activity in extracts prepared from cells during stages I and II. The activity during exponential growth is only 6.6% of the maximum and that in free spores is only 3.3%. Conservation of the purine nucleoside phosphorylase during sporulation is apparent as shown by the gradual increase in heat resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204910"} {"pmid": "4204911", "title": "Mapping of rod mutants of Bacillus subtilis.", "content": "Mapping of rod mutants of Bacillus subtilis. Nine class A salt-dependent rod mutants were mapped on the Bacillus subtilis genome by PBS1-mediated transduction. They are distributed into two small linkage groups designated rod B and rod C; mutations in rod B are over 80% cotransducible with pheA and different mutations in rod C are 12 to 21% cotransducible with hisA. It is established that neither rod B nor rod C is linked by transformation to the other identified rod mutations present in 168-ts-200B and 8332 glu(-). It is hypothesized that salt-dependent mutations are due to enzyme alterations which are corrected by high salt concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204911"} {"pmid": "4204912", "title": "Synthesis of pulcherriminic acid by Bacillus subtilis.", "content": "Synthesis of pulcherriminic acid by Bacillus subtilis. The pathway of pulcherriminic acid synthesis in Bacillus subtilis strains AM and AM-L11 (a leucine-requiring auxotroph) was investigated. Determinations of radioactivity in pulcherriminic acid synthesized by cells growing in media containing (14)C-labeled amino acids indicated that B. subtilis produced pulcherriminic acid from l-leucine. The organism utilized the carbon skeletons of two l-leucine molecules to synthesize one molecule of pulcherriminic acid. Similar results were obtained with starved cell suspensions. Growing cells formed significant amounts of pulcherriminic acid only in media including a carbohydrate such as starch. However, carbohydrate carbon was not required for the synthesis of pulcherriminic acid molecules. Data obtained with cell suspensions supported the hypothesis that cyclo-l-leucyl-l-leucyl is an intermediate in pulcherriminic acid biosynthesis and indicated that molecular oxygen is required for the conversion of cyclo-l-leucyl-l-leucyl to pulcherriminic acid. A pathway for the synthesis of pulcherrimin from l-leucine in B. subtilis is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204912"} {"pmid": "4204914", "title": "Perinatal tips.", "content": "Perinatal tips.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204914"} {"pmid": "4204913", "title": "Isotopic study of control of the lysine biosynthetic pathway during sporulation of Bacillus cereus.", "content": "Isotopic study of control of the lysine biosynthetic pathway during sporulation of Bacillus cereus. The extent of incorporation of aspartate into dipicolinic acid and into various amino compounds was determined in Bacillus cereus at various times before, during, and near the end of synthesis of dipicolinic acid. The purpose of this study was to gain further information on the in vivo control of the biosynthesis of amino acids derived from aspartate. Control of the lysine biosynthetic pathway was of particular interest with regard to sporulation, owing to the important role of diaminopimelate and dipicolinate in the structure of the spore. As synthesis of dipicolinate was initiated, incorporation of carbon derived from aspartate was funneled preferentially into this compound as compared with others of the aspartate group. Incorporation into lysine essentially stopped just before the synthesis of dipicolinate began. This is consistent with the previously observed disappearance at this time of diaminopimelic acid decarboxylase in cell-free extracts. Synthesis of diaminopimelate continued during the time of synthesis of dipicolinate. The previous suggestion that diaminopimelate might exert negative control on one of the enzymes between dihydrodipicolinate and diaminopimelate is thus considered unlikely. The possibility is discussed that synthesis of dipicolinate is favored by an increase in the rate of synthesis of dihydrodipicolinate rather than by a block in its rate of utilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204913"} {"pmid": "4204901", "title": "Induction of psychological death in rhesus monkeys.", "content": "Induction of psychological death in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204901"} {"pmid": "4204917", "title": "Bridging a cultural gap for better patient care.", "content": "Bridging a cultural gap for better patient care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204917"} {"pmid": "4204916", "title": "Shoulder girdle neuritis: a clinical and electrophysiological evaluation.", "content": "Shoulder girdle neuritis: a clinical and electrophysiological evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204916"} {"pmid": "4204915", "title": "Tropical sprue in South Vietnam.", "content": "Tropical sprue in South Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204915"} {"pmid": "4204918", "title": "An experiment in postgraduate medical education: an orientation program for residents in clinical research.", "content": "An experiment in postgraduate medical education: an orientation program for residents in clinical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204918"} {"pmid": "4204919", "title": "Acute exertional rhabdomyolysis: a syndrome of increasing importance to the military physician.", "content": "Acute exertional rhabdomyolysis: a syndrome of increasing importance to the military physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204919"} {"pmid": "4204920", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204920"} {"pmid": "4204922", "title": "A fatal case of hexachlorophene poisoning.", "content": "A fatal case of hexachlorophene poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204922"} {"pmid": "4204921", "title": "Multiple intracranial arterial aneurysms: current thoughts about diagnosis and treatment.", "content": "Multiple intracranial arterial aneurysms: current thoughts about diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204921"} {"pmid": "4204923", "title": "Drug induced intrahepatic cholestatic jaundice: case reports.", "content": "Drug induced intrahepatic cholestatic jaundice: case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204923"} {"pmid": "4204925", "title": "Editorial: The uniformed services medical school.", "content": "Editorial: The uniformed services medical school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204925"} {"pmid": "4204924", "title": "Vesicoureteral reflux: a review.", "content": "Vesicoureteral reflux: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204924"} {"pmid": "4204926", "title": "Sitting on a basketball: how it feels to be a paraplegic.", "content": "Sitting on a basketball: how it feels to be a paraplegic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204926"} {"pmid": "4204927", "title": "The dissociation between renal HCO3- reabsorption and H+ secretion in the skate, Raja erinacea.", "content": "The dissociation between renal HCO3- reabsorption and H+ secretion in the skate, Raja erinacea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204927"} {"pmid": "4204929", "title": "Letter: The antimalarial activity of RC-12 against gametocytes and sporogony of Plasmodium cynomolgi.", "content": "Letter: The antimalarial activity of RC-12 against gametocytes and sporogony of Plasmodium cynomolgi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204929"} {"pmid": "4204930", "title": "Letter: Circadian rhythm in the parasitaemia of the primate haemoflagellate, Trypanosoma minasense.", "content": "Letter: Circadian rhythm in the parasitaemia of the primate haemoflagellate, Trypanosoma minasense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204930"} {"pmid": "4204941", "title": "Polycholorinated biphenyls. VI. 2,3,7,8-tetrachlorodibenzofuran, a critical byproduct in the synthesis of 2,2',4,4',5,5'-hexachlorobiphenyl by the Ullmann reaction.", "content": "Polycholorinated biphenyls. VI. 2,3,7,8-tetrachlorodibenzofuran, a critical byproduct in the synthesis of 2,2',4,4',5,5'-hexachlorobiphenyl by the Ullmann reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204941"} {"pmid": "4204944", "title": "Esophageal intramural diverticulosis: a clinical and pathological survey.", "content": "Esophageal intramural diverticulosis: a clinical and pathological survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204944"} {"pmid": "4204950", "title": "Inhibition of metabolism by hydrostatic pressure: what limits microbial growth?", "content": "Inhibition of metabolism by hydrostatic pressure: what limits microbial growth?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204950"} {"pmid": "4204951", "title": "Glycyl-L-leucine hydrolase, a versatile 'master' dipeptidase from monkey small intestine.", "content": "Glycyl-L-leucine hydrolase, a versatile 'master' dipeptidase from monkey small intestine. 1. A highly active and electrophoretically homogeneous dipeptidase was purified from the soluble extracts of monkey small-intestinal mucosa. 2. By gel-filtration studies the molecular weight of the enzyme was found to be 107000. It is composed of two identical, subunits of molecular weight 54000. 3. A paper-chromatographic method of dipeptidase assay was developed to overcome some of the difficulties encountered in the generally used spectrophotometric procedure. By using this method, the K(m) and k(0) values of a few substrates were determined. 4. The substrate specificity of the enzyme was investigated in great detail with substrates of a wide range of possible structural types. The enzyme hydrolyses a very large proportion of the range of dipeptides tested. This enzyme, which exhibits such a wide range of action, has been termed the ;master' dipeptidase of the intestine. Glycylglycine, glycyl-l-proline, glycyl-l-histidine, l-prolylglycine and some of the arginine- and aspartic acid-containing dipeptides were not substrates and are possibly hydrolysed by other peptidases. These results therefore suggest that in the intestine the number of dipeptidases is rather limited. 5. In the light of these findings, the implications on the role of dipeptidases in intestinal peptide transport are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204951"} {"pmid": "4204953", "title": "Purification and some properties of rabbit anti-ovalbumin.", "content": "Purification and some properties of rabbit anti-ovalbumin. Unlike previous reports that the ovalbumin-anti-ovalbumin complex did not dissociate completely in acid media, our results showed complete dissociation of the complex both in 1.2m-acetic acid, pH2.3, and in KCl-HCl, pH2.2, I 0.06. Thus Sephadex chromatography of the solution obtained by dissolving the antigen-antibody precipitate in these media repeatedly gave two peaks corresponding to anti-ovalbumin and ovalbumin. Further, gel-diffusion and immunoelectrophoresis experiments showed that the phosphate groups of ovalbumin are not involved in the antigenic sites. The antibody thus purified was more easily precipitated than previous preparations. The molecular weight and Stokes radius of the antibody were calculated from its gel-filtration behaviour and were found to be 148000 and 4.8nm respectively. The molecular weight determined by sodium dodecyl sulphate-polyacrylamide gel electrophoresis was essentially similar (about 0.7% lower).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204953"} {"pmid": "4204952", "title": "Purification and some properties of cytoplasmic aspartate aminotransferase from sheep liver.", "content": "Purification and some properties of cytoplasmic aspartate aminotransferase from sheep liver. 1. A procedure for the purification of the cytoplasmic isoenzyme of aspartate aminotransferase from sheep liver is described. 2. The purified isoenzyme shows a single component in the ultracentrifuge at pH7.6 and forms a single protein band on agar-gel electrophoresis at pH6.3 or 8.6, as well as when stained for protein or activity after polyacrylamide-gel or cellulose acetate electrophoresis at pH8.8. 3. Immunoelectrophoresis on agar gel yields only one precipitin arc associated with the protein band, with rabbit antiserum to the purified isoenzyme. By immunodiffusion, cross-reaction was detected between the cytoplasmic isoenzymes from sheep liver and pig heart, but not between the cytoplasmic and mitochondrial sheep liver isoenzymes. 4. The s(20,w) of the enzyme is 5.69S and the molecular weight determined by sedimentation equilibrium is 88900; 19313 molecules of oxaloacetate were formed/min per molecule of enzyme at pH7.4 and 25 degrees C. 5. The amino acid composition of the isoenzyme is presented. It has about 790 residues per molecule. 6. The holoenzyme has a maximum of absorption at 362nm at pH7.6 and 25 degrees C. 7. A value of 2.1 was found for the coenzyme/enzyme molar ratio. 8. The purified enzyme revealed two bands of activity on polyacrylamide-gel electrophoresis at pH7.4 and an extra, faster, band in some circumstances. These bands occurred even when dithiothreitol was present throughout the isolation procedure. 9. Three main bands were obtained by electrofocusing on polyacrylamide plates with pI values 5.75, 5.56 and 5.35. 10. Structural similarities with cytoplasmic isoenzymes from other organs are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204952"} {"pmid": "4204954", "title": "Polymerization of proteins with glutaraldehyde. Soluble molecular-weight markers.", "content": "Polymerization of proteins with glutaraldehyde. Soluble molecular-weight markers. Glutaraldehyde is well known for its ability to react with proteins and to produce insoluble cross-linked aggregates. In contrast with this situation, conditions are described here which yield covalently linked soluble protein oligomers. The procedure is applicable to a wide range of proteins, and by slight variation in the reaction conditions, soluble polymers in the molecular weight range 3x10(4)-2x10(7) were produced. The products are valuable as molecular-weight markers, e.g. in sodium dodecyl sulphate-polyacrylamide-gel electrophoresis. The inherent similarities of these oligomers make them superior to commercial molecular-weight protein markers, which may have marked differences in composition and charge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204954"} {"pmid": "4204955", "title": "Use of affinity chromatography for the quantitative study of acceptor-ligand interactions: The lactose synthetase system.", "content": "Use of affinity chromatography for the quantitative study of acceptor-ligand interactions: The lactose synthetase system. From the effects of N-acetyl-d-glucosamine and d-glucose on the elution of the A protein of human lactose synthetase from a column of Sepharose-alpha-lactalbumin, values of 200m(-1) and 0.57m(-1) are deduced for the association constants describing the interaction between the enzyme and the respective monosaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204955"} {"pmid": "4204959", "title": "The size of the Langerhans' islets in infants with severe jaundice of varying etiology.", "content": "The size of the Langerhans' islets in infants with severe jaundice of varying etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204959"} {"pmid": "4204960", "title": "Effects of bilirubin loading of pregnant rats on hepatic UDP-glucuronyltransferase activity in the offspring.", "content": "Effects of bilirubin loading of pregnant rats on hepatic UDP-glucuronyltransferase activity in the offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204960"} {"pmid": "4204964", "title": "The structure of the mitochondrial matrix.", "content": "The structure of the mitochondrial matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204964"} {"pmid": "4204965", "title": "Changes of the ultrastructural pattern of the nucleus and nucleolus in regenerating rat liver.", "content": "Changes of the ultrastructural pattern of the nucleus and nucleolus in regenerating rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204965"} {"pmid": "4204966", "title": "Organization of amphibian extraocular muscles.", "content": "Organization of amphibian extraocular muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204966"} {"pmid": "4204967", "title": "Ultrastructure of neurosecretory cells in the brain of the crab Rhithropanopeus harrisi (Gould).", "content": "Ultrastructure of neurosecretory cells in the brain of the crab Rhithropanopeus harrisi (Gould).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204967"} {"pmid": "4204968", "title": "Periodicity of infectivity of plasmodial gametocytes: the \"Hawking phenomenon\".", "content": "Periodicity of infectivity of plasmodial gametocytes: the \"Hawking phenomenon\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204968"} {"pmid": "4204969", "title": "Experimental infection of African baboon (Papio cynocephalus) with Brugia malayi.", "content": "Experimental infection of African baboon (Papio cynocephalus) with Brugia malayi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204969"} {"pmid": "4204970", "title": "A new biological assay, utilizing parasitic protozoa, for screening carcinogenic substances which induce bladder cancer in man and other mammals.", "content": "A new biological assay, utilizing parasitic protozoa, for screening carcinogenic substances which induce bladder cancer in man and other mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204970"} {"pmid": "4204972", "title": "\"Contractile interstitial cells\" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies.", "content": "\"Contractile interstitial cells\" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies. In the lungs of healthy rats, humans, lambs, and monkeys, about 50% of the alveolar interstitial cells-resembling fibroblasts-contain bundles of fibrils measuring 30-80 A in diameter. Immunofluorescence studies on frozen sections of rat lung demonstrate that many interstitial cells bind sera containing antiactin antibodies. On account of these two sets of findings and our additional in vitro studies suggesting alveolar tissue contraction due to hypoxia or epinephrine, we postulate that the alveolar septa contain contractile cells different from that of smooth muscle. For these cells we propose the name of \"contractile interstitial cells.\" Such cells lie within the thick portion of the air-blood barrier and around the pre- or postcapillary vessels. Hence it is possible that they play a role in the autoregulation of ventilation/perfusion (V/Q) ratio, particularly in hypoxic pulmonary hypertension. These findings, demonstrating a contractile system other than bronchial and arterial smooth muscle, suggest that the alveolus should no more be conceived as a passive \"organ.\"", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204972"} {"pmid": "4204973", "title": "Isolation of ciliated or unciliated basal bodies from the rabbit oviduct.", "content": "Isolation of ciliated or unciliated basal bodies from the rabbit oviduct. Techniques have been developed for the isolation of basal bodies with cilia attached or for the isolation of only basal bodies from the rabbit oviduct. Oviducts are removed, cut open, and placed in an extraction medium composed of 0.25 M sucrose, 0.001 M EDTA, 0.025 M KCl, 0.02 M Hepes buffer pH 7.5, and 0.05% Triton X-100. After the oviduct is agitated in this medium on a Vortex mixer for (1/2) h, the lumenal cortex of each ciliated cell, containing 200-300 basal bodies with cilia attached, is released as a unit. The cortices and the intact nuclei, which are also released from the disrupted cells, form a pellet when the extraction medium is centrifuged at 600 g for 10 min. When cortices which contain only basal bodies are to be isolated, the oviduct is subjected to conditions which remove the cilia prior to being processed as above. The cilia are removed when the oviduct is placed in a medium of 0.25 M sucrose, 0.01 M CaCl(2), 0.02 M Pipes buffer pH 5.5, and 0.05% Triton X-100 and continuously agitated for 15 min on a Vortex mixer. The low pH and Ca(++) solubilize the transition region of the cilium and also prevent the cell from being disrupted. The cortices can be partially purified if the 600-g pellet is resuspended in 2.2 M sucrose pH 6.5 and centrifuged at 40,000 g for 2 h. Under these conditions, 85% of the nuclei form a pellet and the cortices float to the surface of the sucrose. In addition to the basal bodies or basal bodies with cilia, the cortices contain some adherent cytoplasm, a few fibers, and a few vesicles which may be remnants of mitochondria or endoplasmic reticulum. The structure of the cilia and the basal bodies isolated with either procedure is normal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204973"} {"pmid": "4204975", "title": "Calcium and flagellar response during the chemotaxis of bracken spermatozoids.", "content": "Calcium and flagellar response during the chemotaxis of bracken spermatozoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204975"} {"pmid": "4204974", "title": "Porous substructure of the glomerular slit diaphragm in the rat and mouse.", "content": "Porous substructure of the glomerular slit diaphragm in the rat and mouse. The highly ordered, isoporous substructure of the glomerular slit diaphragm was revealed in rat and mouse kidneys fixed by perfusion with tannic acid and glutaraldehyde. The slit diaphragm was similar in both animal species and appeared as a continuous junctional band, 300-450 A wide, consistently present within all slits formed by the epithelial foot processes. The diaphragm exhibited a zipper-like substructure with alternating, periodic cross bridges extending from the podocyte plasma membranes to a central filament which ran parallel to and equidistant from the cell membranes. The dimensions and spacing of the cross bridges defined a uniform population of rectangular pores approximately 40 by 140 A in cross section and 70 A in length. The total area of the pores was calculated to be about 2-3% of the total surface area of the glomerular capillaries. Physiological data indicate that the glomerular filter functions as if it were an isoporous membrane which excludes proteins larger than serum albumin. The similarity between the dimensions of the pores in the slit diaphragm and estimates for the size and shape of serum albumin supports the conclusion from tracer experiments that the slit diaphragm may serve as the principal filtration barrier to plasma proteins in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204974"} {"pmid": "4204976", "title": "Macromolecular requirements for the initiation and maintenance of DNA synthesis during the cell cycle of Tetrahymena pyriformis.", "content": "Macromolecular requirements for the initiation and maintenance of DNA synthesis during the cell cycle of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204976"} {"pmid": "4204977", "title": "The subcellular distribution of lysosomal hydrolases in the Harding-Passey melanoma.", "content": "The subcellular distribution of lysosomal hydrolases in the Harding-Passey melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204977"} {"pmid": "4204978", "title": "Long-term studies of iron metabolism in normal males: comparison of red blood cell radioactivity with whole-body counter data.", "content": "Long-term studies of iron metabolism in normal males: comparison of red blood cell radioactivity with whole-body counter data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204978"} {"pmid": "4204979", "title": "99mTc-tetracyclines: preparation and biological evaluation.", "content": "99mTc-tetracyclines: preparation and biological evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204979"} {"pmid": "4204980", "title": "Use of 2-(4'-hydroxybenzeneazo)benzoic acid to study the binding of L-thyroxine to serum albumins.", "content": "Use of 2-(4'-hydroxybenzeneazo)benzoic acid to study the binding of L-thyroxine to serum albumins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204980"} {"pmid": "4204971", "title": "Hepatitis B antigen-positive hepatitis in an Israeli family.", "content": "Hepatitis B antigen-positive hepatitis in an Israeli family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204971"} {"pmid": "4204981", "title": "Biological significance of serum albumin binding parameters determined in vitro for clofibrate-related hypolipemic drugs: use of 2-(4'-hydroxybenzeneazo)benzoic acid to mirror L-thyroxine binding to and displacement from serum albumins.", "content": "Biological significance of serum albumin binding parameters determined in vitro for clofibrate-related hypolipemic drugs: use of 2-(4'-hydroxybenzeneazo)benzoic acid to mirror L-thyroxine binding to and displacement from serum albumins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204981"} {"pmid": "4204983", "title": "Absence of an electron microscopic substructure in intact flagella of Proteus mirabilis and Bacillus subtilis.", "content": "Absence of an electron microscopic substructure in intact flagella of Proteus mirabilis and Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204983"} {"pmid": "4204982", "title": "In vitro hydrolysis of oxazepam succinate half-ester by a stereospecific soluble esterase from different animal species.", "content": "In vitro hydrolysis of oxazepam succinate half-ester by a stereospecific soluble esterase from different animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204982"} {"pmid": "4204987", "title": "Proceedings: Physical data for electron therapy.", "content": "Proceedings: Physical data for electron therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204987"} {"pmid": "4204986", "title": "Skeletal fluorosis and dietary calcium, vitamin C and protein.", "content": "Skeletal fluorosis and dietary calcium, vitamin C and protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204986"} {"pmid": "4204988", "title": "Proceedings: Elective radiotherapy of the cervical region in carcinoma of the head and neck.", "content": "Proceedings: Elective radiotherapy of the cervical region in carcinoma of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204988"} {"pmid": "4204989", "title": "The precipitin response induced in calves by a single experimental infection with Fasciola hepatica.", "content": "The precipitin response induced in calves by a single experimental infection with Fasciola hepatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204989"} {"pmid": "4204990", "title": "A new intradermal test antigen for the diagnosis of contagious bovine pleuropneumonia.", "content": "A new intradermal test antigen for the diagnosis of contagious bovine pleuropneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204990"} {"pmid": "4204991", "title": "Calf immunoglobulins and congenital malformation.", "content": "Calf immunoglobulins and congenital malformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204991"} {"pmid": "4204992", "title": "IgA immunoglobulin levels in porcine sera and mammary secretions.", "content": "IgA immunoglobulin levels in porcine sera and mammary secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204992"} {"pmid": "4204993", "title": "Plasma protein binding of digitoxin and digoxin in several mammalian species.", "content": "Plasma protein binding of digitoxin and digoxin in several mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204993"} {"pmid": "4204994", "title": "Abnormal behavioural patterns in dogs with cleft palates.", "content": "Abnormal behavioural patterns in dogs with cleft palates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204994"} {"pmid": "4204995", "title": "A sensitive, direct method for the measurement of water loss from body surfaces.", "content": "A sensitive, direct method for the measurement of water loss from body surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204995"} {"pmid": "4204996", "title": "Fibrin deposits in the Kiil dialyser.", "content": "Fibrin deposits in the Kiil dialyser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204996"} {"pmid": "4204997", "title": "Food iron absorption in man. 3. Effect of iron salt, ascorbic acid and desferrioxamine on the isotopic exchange between native food iron and an extrinsic inorganic iron tracer.", "content": "Food iron absorption in man. 3. Effect of iron salt, ascorbic acid and desferrioxamine on the isotopic exchange between native food iron and an extrinsic inorganic iron tracer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204997"} {"pmid": "4204998", "title": "Pathophysiologic basis of therapy for shock and trauma syndromes: use of sequential cardiorespiratory measurements to describe natural histories and evaluate possible mechanisms.", "content": "Pathophysiologic basis of therapy for shock and trauma syndromes: use of sequential cardiorespiratory measurements to describe natural histories and evaluate possible mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204998"} {"pmid": "4205000", "title": "Radionuclide clearance techniques.", "content": "Radionuclide clearance techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205000"} {"pmid": "4204999", "title": "Therapy of nutritional failure.", "content": "Therapy of nutritional failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4204999"} {"pmid": "4205001", "title": "Radiopharmaceuticals for renal studies.", "content": "Radiopharmaceuticals for renal studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205001"} {"pmid": "4205002", "title": "Uptake and removal of cortisol by canine erythrocytes in various electrolyte solutions.", "content": "Uptake and removal of cortisol by canine erythrocytes in various electrolyte solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205002"} {"pmid": "4205008", "title": "Sarcosporidiosis in psittaciformes.", "content": "Sarcosporidiosis in psittaciformes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205008"} {"pmid": "4205009", "title": "Studies on hydatidosis in Indian buffaloes (Bubalus bubalis). I. Some serological observations in natural infections of hydatids in buffaloes.", "content": "Studies on hydatidosis in Indian buffaloes (Bubalus bubalis). I. Some serological observations in natural infections of hydatids in buffaloes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205009"} {"pmid": "4205010", "title": "Studies on hydatidosis in Indian buffaloes (Bubalus bubalis). II. Antigenicity of buffalo hydatid cyst fluid.", "content": "Studies on hydatidosis in Indian buffaloes (Bubalus bubalis). II. Antigenicity of buffalo hydatid cyst fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205010"} {"pmid": "4205011", "title": "The fine structure of the conducting system of the monkey heart (Macaca mulatta). I. The sino-atrial node and the internodal connections.", "content": "The fine structure of the conducting system of the monkey heart (Macaca mulatta). I. The sino-atrial node and the internodal connections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205011"} {"pmid": "4205012", "title": "Alteration of RNA synthesis in vitro with an endogenous regulating factor of cytodifferentiation of Streptomyces griseus.", "content": "Alteration of RNA synthesis in vitro with an endogenous regulating factor of cytodifferentiation of Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205012"} {"pmid": "4205013", "title": "Induced production of beta-galactosidase in Streptomyces griseus.", "content": "Induced production of beta-galactosidase in Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205013"} {"pmid": "4205014", "title": "Effects of the oxathins DCMO and DCMOD on growth, proteins, oxidizing enzymes, and HCN production of low-temperature basidiomycete.", "content": "Effects of the oxathins DCMO and DCMOD on growth, proteins, oxidizing enzymes, and HCN production of low-temperature basidiomycete.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205014"} {"pmid": "4205015", "title": "Arhinencephaly unilateralis, uveal coloboma, and lens reduplication.", "content": "Arhinencephaly unilateralis, uveal coloboma, and lens reduplication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205015"} {"pmid": "4205016", "title": "Sequential studies of experimentally induced ovine listerial abortion: clinical changes and bacteriologic examinations.", "content": "Sequential studies of experimentally induced ovine listerial abortion: clinical changes and bacteriologic examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205016"} {"pmid": "4205017", "title": "Sequential studies of experimentally induced ovine listerial abortion: pathologic changes.", "content": "Sequential studies of experimentally induced ovine listerial abortion: pathologic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205017"} {"pmid": "4205018", "title": "Ultrastructure of pulmonary alveoli of the calf.", "content": "Ultrastructure of pulmonary alveoli of the calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205018"} {"pmid": "4205019", "title": "Immunization of dogs against human chorionic gonadotropin.", "content": "Immunization of dogs against human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205019"} {"pmid": "4205020", "title": "Purification and characterization of hemolysin produced by Listeria monocytogenes.", "content": "Purification and characterization of hemolysin produced by Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205020"} {"pmid": "4205021", "title": "Clearing technique for preparation and photography of anatomic specimens of blood vessels of female genitalia.", "content": "Clearing technique for preparation and photography of anatomic specimens of blood vessels of female genitalia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205021"} {"pmid": "4205023", "title": "The formation of H2-pteroate analogs from PABA-antagonists in a cell-free system of E. coli.", "content": "The formation of H2-pteroate analogs from PABA-antagonists in a cell-free system of E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205023"} {"pmid": "4205022", "title": "Effect of metabolic inhibitors on mesenteric arterial smooth muscle.", "content": "Effect of metabolic inhibitors on mesenteric arterial smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205022"} {"pmid": "4205024", "title": "Rubella: laboratory aspects.", "content": "Rubella: laboratory aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205024"} {"pmid": "4205025", "title": "Present status of vaccines for rubella.", "content": "Present status of vaccines for rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205025"} {"pmid": "4205026", "title": "Iatrogenic perforations of the esophagus. Therapeutic considerations.", "content": "Iatrogenic perforations of the esophagus. Therapeutic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205026"} {"pmid": "4205027", "title": "Metabolic effects of hypoglycemic sulfonylureas. IV. Interference of sulfonylureas with mitochondrial oxidative phosphorylation.", "content": "Metabolic effects of hypoglycemic sulfonylureas. IV. Interference of sulfonylureas with mitochondrial oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205027"} {"pmid": "4205028", "title": "Propargyl amine-induced irreversibel inhibition of non-flavin-linked amine.", "content": "Propargyl amine-induced irreversibel inhibition of non-flavin-linked amine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205028"} {"pmid": "4205029", "title": "Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides.", "content": "Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205029"} {"pmid": "4205032", "title": "Pseudothrombocytopenia: manifestation of a new type of platelet agglutinin.", "content": "Pseudothrombocytopenia: manifestation of a new type of platelet agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205032"} {"pmid": "4205033", "title": "Radioimmunoassay of calcitonin in human plasma.", "content": "Radioimmunoassay of calcitonin in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205033"} {"pmid": "4205034", "title": "Quantitation of serum IgG by solid-phase radioimmunoassay.", "content": "Quantitation of serum IgG by solid-phase radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205034"} {"pmid": "4205035", "title": "Variables in the laboratory diagnosis of Fabry's disease by measurement of methylumbelliferyl-alpha-galactosidase activity.", "content": "Variables in the laboratory diagnosis of Fabry's disease by measurement of methylumbelliferyl-alpha-galactosidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205035"} {"pmid": "4205036", "title": "Measurement of alpha 1-antitrypsin in serum, by immunodiffusion and by enzymatic assay.", "content": "Measurement of alpha 1-antitrypsin in serum, by immunodiffusion and by enzymatic assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205036"} {"pmid": "4205037", "title": "Quantitative determination of hepatitis B antigen by means of radial immunodiffusion.", "content": "Quantitative determination of hepatitis B antigen by means of radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205037"} {"pmid": "4205038", "title": "Antigen binding and complement fixing activity of IgM molecules reassociated in the presence and absence of J chains.", "content": "Antigen binding and complement fixing activity of IgM molecules reassociated in the presence and absence of J chains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205038"} {"pmid": "4205040", "title": "Separation and characterization of cardiac antigen proteins.", "content": "Separation and characterization of cardiac antigen proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205040"} {"pmid": "4205039", "title": "Non-specific cytotoxicity by T cells activated with plant mitogens in vitro and the requirement for plant agents during the killing reaction.", "content": "Non-specific cytotoxicity by T cells activated with plant mitogens in vitro and the requirement for plant agents during the killing reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205039"} {"pmid": "4205042", "title": "Periovulatory time courses of circulating gonadotropic and ovarian hormones in the rhesus monkey.", "content": "Periovulatory time courses of circulating gonadotropic and ovarian hormones in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205042"} {"pmid": "4205044", "title": "The application of the maize-derived gene competition model to the problem of dosage compensation in Drosophila.", "content": "The application of the maize-derived gene competition model to the problem of dosage compensation in Drosophila. The gene competition model, originally formulated from studies on the regulation of alcohol dehydrogenase activity in maize, is also applicable to the phenomenon of dosage compensation in Drosophila. The model accounts for the absence of dosage compensation in sex determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205044"} {"pmid": "4205045", "title": "Mutation induction in the male recombination strains of Drosophila melanogaster.", "content": "Mutation induction in the male recombination strains of Drosophila melanogaster. One group of the second chromosome lines isolated from a southern Texas population of Drosophila melanogaster, which has been known to show relatively high frequencies of male recombinations, was found to increase the frequency of sex-linked recessive lethal mutations from a control frequency of 0.18% to 1.63%. The second group, which showed a very much reduced frequency of male recombinations, was found to cause a slight increase to 0.48%, although it was not statistically significant. The first group was also tested for the recessive lethal mutation frequency in the second chromosome; the frequency increased from a control frequency of 0.28% to 2.82%. Mapping of a portion of the sex-linked lethals indicated a distribution along the entire X chromosome, although there was a tendency of clustering towards the tip of the X chromosome. One sex-linked lethal line so far tested was found to be associated with an inversion (approximate breakpoints, 14A-18A). It was suggested that the element causing male recombination might be similar to the hi mutator gene studied earlier by Ives (1950).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205045"} {"pmid": "4205046", "title": "Developmental and genetic studies on kynurenine hydroxylase from Drosophila melanogaster.", "content": "Developmental and genetic studies on kynurenine hydroxylase from Drosophila melanogaster. The level of kynurenine hydroxylase was measured throughout the development of wild type and the eye color mutants v, cn, st, ltd, cd, kar, w, ca, bri and p(P) of Drosophila melanogaster. In all cases except cn a bimodal distribution of enzyme activity during development was observed. Activity is initially detectable in second instar. A maximum is reached in early third instar. Activity declines prior to puparium formation. Shortly after pupation, activity rises dramatically to reach a maximum about five times the peak larval level. Maximum activity persists for a short time, and then falls sharply prior to emergence. No activity is detectable in cn, cn(3), or cn(35K). In pupae which have zero, one, two or three doses of the cn(+) allele, activity is proportional to the number of the + alleles. This provides further evidence that the cn locus contains the structural gene for kynurenine hydroxylase. Kynurenine hydroxylase is a useful gene product for studying the events of imaginal disc differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205046"} {"pmid": "4205048", "title": "The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. II. Analysis of responses in the thorax selection lines.", "content": "The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. II. Analysis of responses in the thorax selection lines. An analysis was made of changes in mean and variance in some thorax selection lines. The decrease of mean thorax length in the stabilizing selection lines (S) was a consequence of a directional selection component, caused by the skewness of the frequency distributions. The slight or temporary increase of the phenotypic variance and the large increase of the mean value in the disruptive selection lines with random mating (D(R)) could be attributed to differences in reproduction between small and large flies (egg production and mating success). Phenotypic variability was high in two disruptive selection lines with compulsory mating of opposite extremes (D(-)). The mechanism of the change in variability was different in these replicate lines. In D(-)-1 the change was obtained by an increase of the environmental and the nonadditive genetic components of the variance. In D(-)-2 almost exclusively an increase of additive genetic variance occurred.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205048"} {"pmid": "4205047", "title": "The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. I. Mean values and variances.", "content": "The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. I. Mean values and variances. Disruptive and stabilizing selection were applied to thorax and wing length in Drosophila melanogaster. Disruptive selection with negative assortative mating (D(-)) practiced on thorax length caused a large increase of the phenotypic variance; practiced on wing length the increase was less striking. Disruptive selection with random mating (D(R)) caused in most lines only a temporary increase in phenotypic variance, but mean values increased considerably. Stabilizing selection (S) on thorax length or wing length did not decrease the phenotypic variance, but the mean value of the selected character declined.-The proportion of flies emerging decreased in all lines, while development time increased. Variance of development time increased in the D(-)-lines. In both D(-)-lines the frequency of flies with an abnormal number of scutellars was high (> 60% in one of the lines) and there was a temporary increase in abnormal segmentation of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205047"} {"pmid": "4205050", "title": "Association of Bacillus cereus with food poisoning in dogs.", "content": "Association of Bacillus cereus with food poisoning in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205050"} {"pmid": "4205051", "title": "Changes in -S-S- linked structures of the sperm tail during epididymal maturation, with comparative observations in sub-mammalian species.", "content": "Changes in -S-S- linked structures of the sperm tail during epididymal maturation, with comparative observations in sub-mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205051"} {"pmid": "4205055", "title": "Poor transformability with novr and eryr donor DNA of some mitomycin-C-sensitive strains of Haemophilus influenzae.", "content": "Poor transformability with novr and eryr donor DNA of some mitomycin-C-sensitive strains of Haemophilus influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205055"} {"pmid": "4205057", "title": "The nature of chromosomal fragments in X-chromosomes of Drosophila melanogaster.", "content": "The nature of chromosomal fragments in X-chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205057"} {"pmid": "4205056", "title": "Strong antimutagenic effects of fluoride on mutation induction by trenimon and I-phenyl-3,3-dimethyltriazene in Drosophila melanogaster.", "content": "Strong antimutagenic effects of fluoride on mutation induction by trenimon and I-phenyl-3,3-dimethyltriazene in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205056"} {"pmid": "4205052", "title": "On the recovery of adhesiveness by trypsin-dissociated cells.", "content": "On the recovery of adhesiveness by trypsin-dissociated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205052"} {"pmid": "4205060", "title": "Putrescine metabolizing enzyme activities in some rat tissues during postnatal development.", "content": "Putrescine metabolizing enzyme activities in some rat tissues during postnatal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205060"} {"pmid": "4205058", "title": "Isometric training of rats--effects upon fast and slow muscle and modification by an anabolic hormone (nandrolone decanoate). I. Female rats.", "content": "Isometric training of rats--effects upon fast and slow muscle and modification by an anabolic hormone (nandrolone decanoate). I. Female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205058"} {"pmid": "4205061", "title": "Studies of the heterogeneity of Streptomyces griseus protease. Isolation and characterization of an alkaline serine protease from commercial pronase-P derived from Streptomyces griseus K1.", "content": "Studies of the heterogeneity of Streptomyces griseus protease. Isolation and characterization of an alkaline serine protease from commercial pronase-P derived from Streptomyces griseus K1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205061"} {"pmid": "4205062", "title": "A rapid micro-assay of gentamicin, kanamycin or streptomycin in serum containing penicillins or cephalosporins.", "content": "A rapid micro-assay of gentamicin, kanamycin or streptomycin in serum containing penicillins or cephalosporins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205062"} {"pmid": "4205063", "title": "Aspects of the pharmacology of gentamicin during the neonatal period.", "content": "Aspects of the pharmacology of gentamicin during the neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205063"} {"pmid": "4205064", "title": "Pseudomonas bacteremia. Evaluation of factors influencing response to therapy.", "content": "Pseudomonas bacteremia. Evaluation of factors influencing response to therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205064"} {"pmid": "4205054", "title": "The kinetics and thermodynamics of death in multicellular organisms.", "content": "The kinetics and thermodynamics of death in multicellular organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205054"} {"pmid": "4205065", "title": "The microbiology of gentamicin resistance.", "content": "The microbiology of gentamicin resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205065"} {"pmid": "4205066", "title": "A new genus and species of cryptosporidiid Coccidia from India.", "content": "A new genus and species of cryptosporidiid Coccidia from India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205066"} {"pmid": "4205067", "title": "Role of Pseudomonas aeruginosa in actinomycosis-like bovine mastitis.", "content": "Role of Pseudomonas aeruginosa in actinomycosis-like bovine mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205067"} {"pmid": "4205068", "title": "Pulmonary gas exchange following hemorrhagic shock and massive blood transfusion in the baboon.", "content": "Pulmonary gas exchange following hemorrhagic shock and massive blood transfusion in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205068"} {"pmid": "4205070", "title": "Nonketotic hyperglycemia and epilepsia partialis continua.", "content": "Nonketotic hyperglycemia and epilepsia partialis continua.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205070"} {"pmid": "4205069", "title": "Membrane leakage in Bacillus subtilis 168 induced by the hop constituents lupulone, humulone, isohumulone and humulinic acid.", "content": "Membrane leakage in Bacillus subtilis 168 induced by the hop constituents lupulone, humulone, isohumulone and humulinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205069"} {"pmid": "4205071", "title": "Purification and properties of a carotene co-oxidizing lipoxygenase from peas.", "content": "Purification and properties of a carotene co-oxidizing lipoxygenase from peas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205071"} {"pmid": "4205072", "title": "Protocatechuate 3,4-dioxygenase. IV. Preparation and properties of apo- and reconstituted enzymes.", "content": "Protocatechuate 3,4-dioxygenase. IV. Preparation and properties of apo- and reconstituted enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205072"} {"pmid": "4205073", "title": "Purification and some properties or erythrocyte carbonic anhydrase from the European moose.", "content": "Purification and some properties or erythrocyte carbonic anhydrase from the European moose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205073"} {"pmid": "4205076", "title": "Late prognosis of severe brain injury in children.", "content": "Late prognosis of severe brain injury in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205076"} {"pmid": "4205077", "title": "Mechanisms of cerebrospinal fluid absorption.", "content": "Mechanisms of cerebrospinal fluid absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205077"} {"pmid": "4205080", "title": "Dose and time dependent suppressive and enhancing effect of cytostatics in vitro on the target cell killing activity of lymphocytes.", "content": "Dose and time dependent suppressive and enhancing effect of cytostatics in vitro on the target cell killing activity of lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205080"} {"pmid": "4205082", "title": "The kinetics and distribution of potassium in the toad bladder.", "content": "The kinetics and distribution of potassium in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205082"} {"pmid": "4205084", "title": "Urea transport in the toad bladder; coupling of urea flows.", "content": "Urea transport in the toad bladder; coupling of urea flows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205084"} {"pmid": "4205083", "title": "Pathways for movement of ions and water across toad urinary bladder. I. Anatomic site of transepithelial shunt pathways.", "content": "Pathways for movement of ions and water across toad urinary bladder. I. Anatomic site of transepithelial shunt pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205083"} {"pmid": "4205075", "title": "Mucociliary abnormalities underlying impaired mucus elimination.", "content": "Mucociliary abnormalities underlying impaired mucus elimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205075"} {"pmid": "4205086", "title": "Congenitally obstructed bladders: fate after prolonged defunctionalization.", "content": "Congenitally obstructed bladders: fate after prolonged defunctionalization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205086"} {"pmid": "4205087", "title": "Variation in bacteriuria with intestinal loop urinary diversions.", "content": "Variation in bacteriuria with intestinal loop urinary diversions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205087"} {"pmid": "4205085", "title": "A study of the dependence of the human erythrocyte glucose transport system on membrane sulfhydryl groups.", "content": "A study of the dependence of the human erythrocyte glucose transport system on membrane sulfhydryl groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205085"} {"pmid": "4205088", "title": "Stone-containing pyelocaliceal diverticulum: embryogenic, anatomic, radiologic and clinical characteristics.", "content": "Stone-containing pyelocaliceal diverticulum: embryogenic, anatomic, radiologic and clinical characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205088"} {"pmid": "4205089", "title": "The negative effects of supervoltage external irradiation in prostatic carcinoma: report of 2 cases.", "content": "The negative effects of supervoltage external irradiation in prostatic carcinoma: report of 2 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205089"} {"pmid": "4205090", "title": "Intravenous hyperalimentation: a useful adjunct in surgery of the azotemic patient.", "content": "Intravenous hyperalimentation: a useful adjunct in surgery of the azotemic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205090"} {"pmid": "4205081", "title": "A century of progress in experimental leprosy.", "content": "A century of progress in experimental leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205081"} {"pmid": "4205104", "title": "Preparation and use of malarial placenta antigen for immunodiffusion studies in a Nigerian population.", "content": "Preparation and use of malarial placenta antigen for immunodiffusion studies in a Nigerian population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205104"} {"pmid": "4205105", "title": "Concomitant infection of albino mice by Trypanosoma cruzi and Schistosoma mansoni. Parasitological parameters.", "content": "Concomitant infection of albino mice by Trypanosoma cruzi and Schistosoma mansoni. Parasitological parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205105"} {"pmid": "4205106", "title": "Studies with the schistosomicide oxamniquine (UK-4271). II. Activity in primates.", "content": "Studies with the schistosomicide oxamniquine (UK-4271). II. Activity in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205106"} {"pmid": "4205107", "title": "Letter: Plasma IgE levels and Schistosoma haematobium infection.", "content": "Letter: Plasma IgE levels and Schistosoma haematobium infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205107"} {"pmid": "4205108", "title": "Hepatozoon-like parasite (schizonts) in the myocardium of the domestic cat.", "content": "Hepatozoon-like parasite (schizonts) in the myocardium of the domestic cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205108"} {"pmid": "4205110", "title": "Neuraminidase and anti-neuraminidase serum: effect on the cell surface properties.", "content": "Neuraminidase and anti-neuraminidase serum: effect on the cell surface properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205110"} {"pmid": "4205109", "title": "Selective serum IgA deficiency. Frequency among 15,200 French blood donors.", "content": "Selective serum IgA deficiency. Frequency among 15,200 French blood donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205109"} {"pmid": "4205111", "title": "Quantitative variation in the G antigen of the Rh blood group system.", "content": "Quantitative variation in the G antigen of the Rh blood group system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205111"} {"pmid": "4205112", "title": "Independence of the Colton and Yt blood group systems.", "content": "Independence of the Colton and Yt blood group systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205112"} {"pmid": "4205099", "title": "A gonadotropin inhibiting principle in the pineal of human fetuses. Evidence for its identity with arginine vasotocin.", "content": "A gonadotropin inhibiting principle in the pineal of human fetuses. Evidence for its identity with arginine vasotocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205099"} {"pmid": "4205100", "title": "Lack of effect of steroids on thyrotropin-releasing hormone (TRH) mediated thyrotropin (TSH) release in man.", "content": "Lack of effect of steroids on thyrotropin-releasing hormone (TRH) mediated thyrotropin (TSH) release in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205100"} {"pmid": "4205113", "title": "Establishment of new mouse and human pigmented melanoma lines in tissue culture.", "content": "Establishment of new mouse and human pigmented melanoma lines in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205113"} {"pmid": "4205114", "title": "Harding-Passey melanoma in the BALB-C mouse as a model for studying the interactions between host macrophages and tumor cells.", "content": "Harding-Passey melanoma in the BALB-C mouse as a model for studying the interactions between host macrophages and tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205114"} {"pmid": "4205116", "title": "Biochemistry of melanin synthesis: in vivo effects of MSH on tyrosinase and melanogenesis of pigmentary system.", "content": "Biochemistry of melanin synthesis: in vivo effects of MSH on tyrosinase and melanogenesis of pigmentary system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205116"} {"pmid": "4205115", "title": "Control of pigment synthesis in culture.", "content": "Control of pigment synthesis in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205115"} {"pmid": "4205117", "title": "Quantitative measurement of melanin as tyrosine equivalents and as weight of purified melanin.", "content": "Quantitative measurement of melanin as tyrosine equivalents and as weight of purified melanin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205117"} {"pmid": "4205118", "title": "Regulatory mechanisms of tyrosinase activity in melanocyte. I.", "content": "Regulatory mechanisms of tyrosinase activity in melanocyte. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205118"} {"pmid": "4205120", "title": "A revised concept of mammalian melanogenesis: the possible synergistic functions of aerobic dopa oxidase and peroxidase. A review.", "content": "A revised concept of mammalian melanogenesis: the possible synergistic functions of aerobic dopa oxidase and peroxidase. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205120"} {"pmid": "4205119", "title": "Histochemical evidence that peroxidase does not affect melanin formation in feather melanocytes.", "content": "Histochemical evidence that peroxidase does not affect melanin formation in feather melanocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205119"} {"pmid": "4205121", "title": "Purification and properties of tyrosinase isoenzymes from hamster melanoma.", "content": "Purification and properties of tyrosinase isoenzymes from hamster melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205121"} {"pmid": "4205123", "title": "The tyrosinase-protyrosinase system in frog epidermis.", "content": "The tyrosinase-protyrosinase system in frog epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205123"} {"pmid": "4205122", "title": "Peroxidase, \"protyrosinase,\" and the multiple forms of tyrosinase in mice.", "content": "Peroxidase, \"protyrosinase,\" and the multiple forms of tyrosinase in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205122"} {"pmid": "4205125", "title": "Immunological studies on malignant melanomas of man.", "content": "Immunological studies on malignant melanomas of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205125"} {"pmid": "4205124", "title": "Hormonal control of melanocytes: MSH-sensitive adenyl cyclase in the Cloudman melanoma.", "content": "Hormonal control of melanocytes: MSH-sensitive adenyl cyclase in the Cloudman melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205124"} {"pmid": "4205127", "title": "Effect of TRH (thyrotropin-releasing hormone) on the fine structure and replication of TSH and prolactin cells in the rat.", "content": "Effect of TRH (thyrotropin-releasing hormone) on the fine structure and replication of TSH and prolactin cells in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205127"} {"pmid": "4205129", "title": "Antibacterial activity of diacetyl and its influence on the keeping quality of milk.", "content": "Antibacterial activity of diacetyl and its influence on the keeping quality of milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205129"} {"pmid": "4205130", "title": "Diffuse lymphoma of the intestines with a monoclonal gammopathy of IgG3 kappa type.", "content": "Diffuse lymphoma of the intestines with a monoclonal gammopathy of IgG3 kappa type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205130"} {"pmid": "4205131", "title": "Plasma cell interstitial pneumonia and macroglobulinemia. A response to corticosteroid and cyclophosphamide therapy.", "content": "Plasma cell interstitial pneumonia and macroglobulinemia. A response to corticosteroid and cyclophosphamide therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205131"} {"pmid": "4205132", "title": "Waldenström's macroglobulinemia in a patient with a chronic biologic false-positive serologic test for syphilis.", "content": "Waldenström's macroglobulinemia in a patient with a chronic biologic false-positive serologic test for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205132"} {"pmid": "4205133", "title": "Candida tropicalis and Torulopsis glabrata fungemia in a patient treated with long-term hyperalimentation.", "content": "Candida tropicalis and Torulopsis glabrata fungemia in a patient treated with long-term hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205133"} {"pmid": "4205135", "title": "Disodium cromoglycate \"Intal\" (Fisons) \"Rynacrom\" (Fisons).", "content": "Disodium cromoglycate \"Intal\" (Fisons) \"Rynacrom\" (Fisons).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205135"} {"pmid": "4205136", "title": "Connecticut gonorrhea screening program.", "content": "Connecticut gonorrhea screening program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205136"} {"pmid": "4205137", "title": "Paraproteinemias.", "content": "Paraproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205137"} {"pmid": "4205138", "title": "Active immunization to 17 beta-estradiol and its effects upon the reproductive cycle of the rhesus monkey.", "content": "Active immunization to 17 beta-estradiol and its effects upon the reproductive cycle of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205138"} {"pmid": "4205139", "title": "Thyroid activation in rats after intrapituitary administration of synthetic thyrotrophin-releasing factor (TRF).", "content": "Thyroid activation in rats after intrapituitary administration of synthetic thyrotrophin-releasing factor (TRF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205139"} {"pmid": "4205140", "title": "Delta 5-3 beta-hydroxysteroid dehydrogenase-delta 5-delta 4- isomerase activity in the corpus luteum of the pregnant rhesus monkey.", "content": "Delta 5-3 beta-hydroxysteroid dehydrogenase-delta 5-delta 4- isomerase activity in the corpus luteum of the pregnant rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205140"} {"pmid": "4205141", "title": "The effect of fetal sex on placental biosynthesis of progesterone.", "content": "The effect of fetal sex on placental biosynthesis of progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205141"} {"pmid": "4205142", "title": "Metabolic effects of oral contraceptives in monkeys fed adequate protein & low proein diets.", "content": "Metabolic effects of oral contraceptives in monkeys fed adequate protein & low proein diets. The effects of 2 oral contraceptives, Ovulen and Norlestrin, were studied in monkeys fed adequate protein and low protein diets. The experiment was carried out in parts. In the first one, the administration of contraceptives was cyclic and similar to that employed in human subjects. In the other experiments, the contraceptives were given continuously and an attempt was made to exaggerate the deleterious effects of the oral contraceptive on the liver by including small doses of a known hepatotoxic agent, aflatoxin (AT). In Experiment 1, 45 female monkeys were divided into 2 groups of 20 and 25 and received an adequate protein (16%) and low protein diet (4%) respectively. Each monkey was fed 1/5 of a tablet of Ovulen or Norlestrin orally for 3 weeks, and then administration was discontinued for 1 week. In Experiment 2, 35 female monkeys were divided into 7 groups of 5 each. All the animals recieved 4% protein diet. 5 groups were tube fed at the rate of 100 cal/kg body weight, while 2 groups were given diet ad libitum. Group I received the diet alone while groups II-V received 10 mcg AT, 25 mcg AT, 10 mcg AT plus 1/5 Ovulen tablets, and 25 mcg AT plus 1/5 Ovulen tablet respectively daily. Groups VI and VII received the diet ad libitum but were orally fed 75 mcg AT and 75 mcg AT plus 1/5 Ovulen tablet respectively. Serum glutamic-oxalacetic transaminase activity and alkaline phosphatase activity were studied at regular intervals after the administation of oral contraceptives in the experiments. Serum proteins and hemoglobin were also determined. Monkeys fed oral contraceptives showed increased serum glutamic-oxalacetic transaminase and alkaline phosphatase activities irrespective of the level of protein in the diet. Livers of animals receiving oral contraceptives were morphologically similar to the controls fed respective diets. The experiments were conducted for a period of almost 2 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205142"} {"pmid": "4205143", "title": "Studies on different strains of vaccinia virus with particular reference to their quality regarding immunogenicity and reactogenicity. 3. Studies in rabbits and monkeys (Macaca mulatta).", "content": "Studies on different strains of vaccinia virus with particular reference to their quality regarding immunogenicity and reactogenicity. 3. Studies in rabbits and monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205143"} {"pmid": "4205144", "title": "Genital listeriosis in Delhi (India): a pilot study.", "content": "Genital listeriosis in Delhi (India): a pilot study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205144"} {"pmid": "4205146", "title": "Editorial: The use of tears for heterozygote detection and genetic counseling.", "content": "Editorial: The use of tears for heterozygote detection and genetic counseling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205146"} {"pmid": "4205145", "title": "Antibody to hepatitis associated antigen in blood donors of Delhi by Sandwich solid phase radioimmunoassay.", "content": "Antibody to hepatitis associated antigen in blood donors of Delhi by Sandwich solid phase radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205145"} {"pmid": "4205150", "title": "Lack of mutagenicity of the cyclamate metabolites in Drosophila.", "content": "Lack of mutagenicity of the cyclamate metabolites in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205150"} {"pmid": "4205152", "title": "Health insurance in Canada--an overview and commentary.", "content": "Health insurance in Canada--an overview and commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205152"} {"pmid": "4205151", "title": "Use of a hyperbaric solution for administration of intrathecal amphotericin B.", "content": "Use of a hyperbaric solution for administration of intrathecal amphotericin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205151"} {"pmid": "4205153", "title": "Traumatic shock in man.", "content": "Traumatic shock in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205153"} {"pmid": "4205154", "title": "Letter: Actions of propranolol in angina pectoris.", "content": "Letter: Actions of propranolol in angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205154"} {"pmid": "4205155", "title": "Letter: Possible Chagas's disease in United States.", "content": "Letter: Possible Chagas's disease in United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205155"} {"pmid": "4205148", "title": "Two-stage model for human enamel demineralization as determined by scanning electron microscope analysis.", "content": "Two-stage model for human enamel demineralization as determined by scanning electron microscope analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205148"} {"pmid": "4205156", "title": "Cisternograms in the primate Macaca mulatta.", "content": "Cisternograms in the primate Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205156"} {"pmid": "4205147", "title": "Statistical relationship between the presence of human subgingival anaerobic diptheroids and periodontal disease.", "content": "Statistical relationship between the presence of human subgingival anaerobic diptheroids and periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205147"} {"pmid": "4205157", "title": "Local cerebral blood flow.", "content": "Local cerebral blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205157"} {"pmid": "4205158", "title": "Neglect after mesencephalic reticular formation lesions.", "content": "Neglect after mesencephalic reticular formation lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205158"} {"pmid": "4205159", "title": "Evaluation of patients with coronary artery disease.", "content": "Evaluation of patients with coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205159"} {"pmid": "4205160", "title": "Specific injuries of sport.", "content": "Specific injuries of sport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205160"} {"pmid": "4205165", "title": "Hemobilia.", "content": "Hemobilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205165"} {"pmid": "4205168", "title": "The value of laparotomy and splenectomy in the staging of 56 patients with Hodgkin's disease.", "content": "The value of laparotomy and splenectomy in the staging of 56 patients with Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205168"} {"pmid": "4205170", "title": "Chromosome studies in paroxysmal nocturnal haemoglobinuria.", "content": "Chromosome studies in paroxysmal nocturnal haemoglobinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205170"} {"pmid": "4205171", "title": "A new unstable haemoglobin: Hb Buenos Aires, beta 85 (F1) Phe leads to Ser.", "content": "A new unstable haemoglobin: Hb Buenos Aires, beta 85 (F1) Phe leads to Ser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205171"} {"pmid": "4205172", "title": "Rhesus and squirrel monkey placental specific antigen(s).", "content": "Rhesus and squirrel monkey placental specific antigen(s).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205172"} {"pmid": "4205173", "title": "Estriol and estetrol in amniotic fluid.", "content": "Estriol and estetrol in amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205173"} {"pmid": "4205174", "title": "Present status of intrauterine diagnosis of genetic defects.", "content": "Present status of intrauterine diagnosis of genetic defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205174"} {"pmid": "4205177", "title": "Formation of cyanide from o-chlorobenzylidene malononitrile and its toxicological significance.", "content": "Formation of cyanide from o-chlorobenzylidene malononitrile and its toxicological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205177"} {"pmid": "4205180", "title": "Symptomatic relief of the pre-varicose syndrome and the symptomatology associated with varicose veins using ergot compounds.", "content": "Symptomatic relief of the pre-varicose syndrome and the symptomatology associated with varicose veins using ergot compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205180"} {"pmid": "4205181", "title": "Ternidens deminutus (Railliet & Henry, 1909) and hookworm in Rhodesia and a review of the treatment of human infections with T. deminutus.", "content": "Ternidens deminutus (Railliet & Henry, 1909) and hookworm in Rhodesia and a review of the treatment of human infections with T. deminutus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205181"} {"pmid": "4205183", "title": "Cell density as a selective parameter in tetrahymena.", "content": "Cell density as a selective parameter in tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205183"} {"pmid": "4205184", "title": "Changes caused by air-drying and alcohol dehydration of spread insect sperm and fungal spore chromosome fibres.", "content": "Changes caused by air-drying and alcohol dehydration of spread insect sperm and fungal spore chromosome fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205184"} {"pmid": "4205187", "title": "Measurement of the potency of allergy extracts by their inhibitory capacities in the radioallergosorbent test.", "content": "Measurement of the potency of allergy extracts by their inhibitory capacities in the radioallergosorbent test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205187"} {"pmid": "4205188", "title": "Increased circulating IgE in tropical eosinophilia.", "content": "Increased circulating IgE in tropical eosinophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205188"} {"pmid": "4205189", "title": "Temperature-induced derepression of tryptophan biosynthesis in a tryptophanyl-transfer ribonucleic acid synthetase mutant of Bacillus subtilis.", "content": "Temperature-induced derepression of tryptophan biosynthesis in a tryptophanyl-transfer ribonucleic acid synthetase mutant of Bacillus subtilis. A tryptophanyl-transfer ribonucleic acid (tRNA) synthetase (l-tryptophan: tRNA ligase adenosine monophosphate, EC 6.1.1.2) mutant (trpS1) of Bacillus subtilis is derepressed for enzymes of the tryptophan biosynthetic pathway at temperatures which reduce the growth rate but still allow exponential growth. Derepression of anthranilate synthase in a tryptophan-supplemented medium (50 mug/ml) is maximal at 36 C, and the differential rate of synthesis is 600- to 2,000-fold greater than that of the wild-type strain or trpS1 revertants. A study of the derepression pattern in the mutant and its revertants indicates that the 5-fluorotryptophan recognition site of the tryptophanyl-tRNA synthetase is an integral part of the repression mechanism. Evidence for a second locus, unlinked to the trpS1 locus, which functions in the repression of tryptophan biosynthetic enzymes is presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205189"} {"pmid": "4205190", "title": "Lactic acid translocation: terminal step in glycolysis by Streptococcus faecalis.", "content": "Lactic acid translocation: terminal step in glycolysis by Streptococcus faecalis. Streptococcus faecalis obtains metabolic energy chiefly from the conversion of glucose to lactic acid; the present experiments deal with the mechanism of lactic acid translocation across the cytoplasmic membrane. Efflux of [(14)C]lactate from preloaded cells was accelerated by raising the external pH, and also by the ionophores nigericin and valinomycin. These results suggest that lactate leaves the cell by an electroneutral process, presumably as lactic acid. Further evidence was obtained by studying the entry of [(14)C]lactate into nonmetabolizing cells. It appears that the membrane is essentially impermeable to the lactate anion, but allows passage of lactic acid. The most persuasive evidence is that, upon establishment of a pH gradient such that the cytoplasm was alkaline, l-[(14)C]lactate accumulated in the cells against the concentration gradient. Accumulation was transient, and dissipated in parallel with the collapse of the pH gradient. The concentration gradient attained at the peak was a function of the pH difference. Ionophores which are known to collapse a pH gradient, such as nigericin and valinomycin, abolished accumulation of l-lactate. We infer that lactic acid translocation, whether into the cells or outward, is an electroneutral process and for that reason the distribution of lactic acid across the membrane is a function of the pH of cytoplasm and medium. The specificity of translocation and its kinetic parameters suggest that it is mediated by a carrier of low specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205190"} {"pmid": "4205192", "title": "Polyamine levels during growth, sporulation, and spore germination of Bacillus megaterium.", "content": "Polyamine levels during growth, sporulation, and spore germination of Bacillus megaterium. Spermidine was the major (>95%) polyamine of Bacillus megaterium in all stages of growth, although it could be replaced completely by spermine. Log-phase cells had 40 to 50% as much spermidine, based on ribonucleic acid (RNA) content, as did either stationary-phase cells or dormant spores; similar results were obtained in three other bacilli including an asporogenous mutant. Polyamine levels were essentially the same in B. megaterium grown in rich or poor media, or in media of high or low ionic strength. Polyamine levels were elevated three- to sixfold by exogenous spermidine without a major effect on growth, sporulation, or subsequent spore germination. During germination, the absolute amount of spermidine remained constant for almost 2 h until net RNA synthesis had lowered the polyamine/RNA ratio to a value close to that in log-phase cells. At this time, the spermidine level began to rise, and thereafter spermidine and RNA increased in parallel. This parallel relationship between the spermidine and RNA levels was abolished by actinomycin D, but not by chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205192"} {"pmid": "4205191", "title": "Extrachromosomal elements in group N streptococci.", "content": "Extrachromosomal elements in group N streptococci. The deoxyribonucleic acid (DNA) of Streptococcus lactis C2, S. cremoris B(1), and S. diacetilactis 18-16 was labeled by growing cells in Trypticase soy broth containing (3)H-labeled thymine. The cells were gently lysed with lysozyme, ethylenediaminetetraacetic acid, and sodium lauryl sulfate. The chromosomal DNA was separated from plasmid DNA by precipitation with 1.0 M sodium chloride. The existence of covalently closed circular DNA in the three organisms was shown by cesium chloride-ethidium bromide equilibrium density gradient centrifugation of the cleared lysate material. In an attempt to correlate the loss of lactose metabolism with the loss of plasmid DNA, lactose-negative mutants of these organisms were examined for the presence of extrachromosomal particles. Covalently closed circular DNA was detected in the lactose-negative mutants of S. lactis C2 and S. diacetilactis 18-16. In S. cremoris B(1), however, no covalently closed circular DNA was observed by using cesium chloride-ethidium bromide gradients. Electron micrographs of the satellite band material from S. lactis C2 and its lactose-negative mutant confirmed the presence of plasmid DNA. Three distinct plasmids having approximate molecular weights of 1.3 x 10(6), 2.1 x 10(6), and 5.1 x 10(6) were observed in both organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205191"} {"pmid": "4205193", "title": "Size distribution of the closed circular deoxyribonucleic acid molecules of Bacillus megaterium: sedimentation velocity and electron microscope measurements.", "content": "Size distribution of the closed circular deoxyribonucleic acid molecules of Bacillus megaterium: sedimentation velocity and electron microscope measurements. The circular deoxyribonucleic acid (DNA) of Bacillus megaterium was fractionated by sedimentation velocity on preparative zonal gradients. The fractions obtained were characterized by analytical sedimentation velocity analysis on neutral and alkaline sucrose gradients, and by contour length measurement by electron microscopy. Each fraction was found to contain circular molecules of one to three discrete sizes, in various combinations of covalently closed and open circular forms. Estimations of the molecular masses of these sizes gave values of 3.9, 6.2, 16.0, 31, and 60 million daltons for the major molecular species. Minor amounts of molecules of 7.6, 11.7, 47, 89, and 112 million daltons were observed in the electron microscope analyses. Length measurements of almost 600 molecules from the various fractions showed that all except six could be placed in distinct size classes. The distribution of molecular sizes in unfractionated circular DNA was shown to consist primarily of the two smallest size classes, although the relative proportions by weight of five of the classes were roughly equivalent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205193"} {"pmid": "4205194", "title": "Magnesium transport in Bacillus subtilis W23 during growth and sporulation.", "content": "Magnesium transport in Bacillus subtilis W23 during growth and sporulation. The active transport of magnesium by cells of Bacillus subtilis strain W23 occurs by a highly specific transport system (Mg(2+) is favored over Mn(2+), Co(2+), or Ca(2+)) that is energy dependent (i.e., glucose is required in minimal medium and the system is inhibited by cyanide and m-chlorophenyl carbonylcyanidehydrazone). The rate of magnesium uptake by log-phase B. subtilis cells follows saturation kinetics with a K(m) of 2.5 x 10(-4) M and a V(max) of 4.4 mumol per min per g (dry weight) at 30 C. Manganese is a competitive inhibitor showing a K(i) of 5 x 10(-4) M. During sporulation the rate of magnesium transport declines. This decline in rate is specific for the magnesium system as the manganese and calcium transport rates increase. The residual magnesium transport function in sporulating cells shows both an altered K(m) and an altered V(max). The magnesium content of late sporulating cells is also lower than that for log-phase cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205194"} {"pmid": "4205195", "title": "Transport of glucose, gluconate, and methyl alpha-D-glucoside by Pseudomonas aeruginosa.", "content": "Transport of glucose, gluconate, and methyl alpha-D-glucoside by Pseudomonas aeruginosa. Glucose transport by Pseudomonas aeruginosa was studied. These studies were enhanced by the use of a mutant, strain PAO 57, which was unable to grow on glucose but which formed the inducible glucose transport system when grown in media containing glucose or other inducers such as 2-deoxy-d-glucose. Both PAO 57 and parental strain PAO transported glucose with an apparent K(m) of 7 muM. Free glucose was concentrated intracellularly by P. aeruginosa PAO 57 over 200-fold above the external level. These data constitute direct evidence that glucose is transported via active transport by P. aeruginosa. Various experimental data clearly indicated that P. aeruginosa PAO transported methyl alpha-d-glucose (alpha-MeGlc) via the glucose transport system. The apparent K(m) of alpha-MeGlc transport was 7 mM which indicated a 1,000-fold lower affinity of the glucose transport system for alpha-MeGlc than for glucose. While only unchanged alpha-MeGlc was detected intracellularly in P. aeruginosa, alpha-MeGlc was actually concentrated intracellularly less than 2-fold over the external level. Membrane vesicles of P. aeruginosa PAO retained transport activity for gluconate. This solute was concentrated intravesicularly several-fold over the external level. A component of the glucose transport system is believed to have been lost during vesicle preparation since glucose per se was not transported. Instead; glucose was converted to gluconate by membrane-associated glucose dehydrogenase and gluconate was then transported into the vesicles. Although this may constitute an alternate system for glucose transport, it is not a necessary prerequisite for glucose transport by intact cells since P. aeruginosa PAO 57, which lacks glucose dehydrogenase, was able to transport glucose at a rate equal to the parental strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205195"} {"pmid": "4205196", "title": "Regulation of aconitase synthesis in Bacillus subtilis: induction, feedback repression, and catabolite repression.", "content": "Regulation of aconitase synthesis in Bacillus subtilis: induction, feedback repression, and catabolite repression. The synthesis of aconitase in Bacillus subtilis wild-type and different citric acid cycle mutants has been studied and the influence of various growth conditions examined. Aconitase is induced by citrate and precursors of citrate and repressed by glutamate. Induction and repression counteract each other, and at equimolar concentrations of citrate and glutamate, aconitase synthesis is unaffected. Induction by citrate can partly overcome catabolite repression of aconitase. Isocitrate dehydrogenase show endogenous induction of aconitase due to citrate accumulation. Leaky mutants defective in citrate synthase and aconitase cannot be induced by citrate, which indicates that they carry a regulatory mutation. The complex regulation of aconitase is discussed with reference to the participation of this enzyme in glutamate biosynthesis and energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205196"} {"pmid": "4205198", "title": "Cell wall turnover at the hemispherical caps of Bacillus subtilis.", "content": "Cell wall turnover at the hemispherical caps of Bacillus subtilis. Cell walls made by Bacillus subtilis bacteria grown in D(2)O medium have buoyant densities in CsCl which are different from walls made by cells grown in H(2)O medium. Cell wall turnover was studied by measuring the change in wall buoyant density after a B. subtilis culture was shifted from growth in D(2)O medium to aeration in H(2)O medium. Walls from the hemispherical caps were isolated after preferential digestion of wall from the cylindrical regions using the B. subtilis autolytic amidase. The walls from the polar regions were found to turn over extensively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205198"} {"pmid": "4205197", "title": "Physiological studies of Bacillus subtilis minicells.", "content": "Physiological studies of Bacillus subtilis minicells. Minicells produced by Bacillus subtilis strains carrying the div IV-B1 mutation, (CU 403 div IV-B1 and CU 403 div IV-B1, tag-1), were purified by a procedure which destroys parental cells with ultrasound, but spares minicells. Such preparations generally contain 10(9) or more minicells/ml and less than 10(4) colony-forming units/ml. Purified minicells are resistant to autolysis in tris(hydroxymethyl)aminomethane buffer, pH 7.5, at 30 C, conditions which result in total lysis of parental cells. Minicells are not completely devoid of autolytic activity, however. The medium in which minicells are produced, the temperature at which purified minicells are incubated, and the genotype of cells from which the minicells are derived all influence the rate of autolysis of purified minicells. These parameters are demonstrated by using minicells obtained from div IV-B1 and div IV-B1, tag-1 strains. Ultrastructural differences have been observed in the products of autolysis of these two minicell strains. Minicells are sensitive to low levels of lysozyme and yield miniprotoplasts when the wall is removed in an osmotically protective environment. Although minicells are unable to grow, they can maintain their integrity over long periods of time, which suggests functional energy metabolism in minicells. Direct measurements of adenosine 5'-triphosphate (ATP) levels by the luciferase assay indicated that minicells can produce ATP. Oxygen consumption, measured by standard respirometry techniques, also indicates functional metabolism in minicells. These findings demonstrate that minicells purified by ultrasound are suitable material for study of physiological processes in anucleate cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205197"} {"pmid": "4205199", "title": "Chemical composition and ultrastructure of native and reaggregated membranes from protoplasts of Bacillus cereus.", "content": "Chemical composition and ultrastructure of native and reaggregated membranes from protoplasts of Bacillus cereus. Conditions were defined for producing protoplasts with lysozyme and isolating the protoplast membranes from cells of Bacillus cereus T harvested late in the exponential growth phase just before sporogenesis. The membranes contained approximately 60% protein, 30% lipid, 6% carbohydrate, and 1% ribonucleic acid. Seventeen proteins were distinguished by molecular size in the membrane solubilized with sodium dodecyl sulfate, and 12 in that with phenol and acetic acid. The lipid fraction consisted of neutral lipids (28%) and phospholipids (72%). Four phospholipids were identified: diphosphatidyl glycerol, phosphatidyl ethanolamine, phosphatidyl glycerol, and lysophosphatidyl ethanolamine. Eighteen fatty acids were identified, with a predominance of branched C(15) and C(17) and of normal C(16) acids. The carbohydrate fraction consisted of neutral hexoses. A clear supernatant solution from the solubilized preparation became reaggregated into membrane by dialysis in the presence of MgCl(2). The reaggregated membrane had the same main components as the native membrane, but the amount and ratio of protein and lipid depended on the buffer and the MgCl(2) concentration. By electron microscopy, the reaggregated membranes appeared as vesicles or sheets, depending on the MgCl(2) concentration. Hexagonal lattices were occasionally detected in the negatively stained ultrastructure of both native and reaggregated membrane fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205199"} {"pmid": "4205200", "title": "Degradation of thymidine by Lactobacillus acidophilus.", "content": "Degradation of thymidine by Lactobacillus acidophilus. Whole cells of Lactobacillus acidophilus are capable of degrading thymidine to thymine, suggesting the presence of thymidine phosphorylase (or thymidine hydrolase). This activity was also demonstrated in cell-free extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205200"} {"pmid": "4205201", "title": "Degree of completion of 3'-terminus of transfer ribonucleic acids of Bacillus subtilis 168 at various developmental stages and asporogenous mutants.", "content": "Degree of completion of 3'-terminus of transfer ribonucleic acids of Bacillus subtilis 168 at various developmental stages and asporogenous mutants. Transfer ribonucleic acids from sporulating cells, spores, sporangia, or stationary-phase asporogenous mutants of Bacillus subtilis all showed a deficiency in the 3'-terminal adenosine moiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205201"} {"pmid": "4205202", "title": "The effect of anti-plasma cell serum on B cells.", "content": "The effect of anti-plasma cell serum on B cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205202"} {"pmid": "4205203", "title": "Characteristics of secretory immune system in human middle ear: implications in otitis media.", "content": "Characteristics of secretory immune system in human middle ear: implications in otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205203"} {"pmid": "4205204", "title": "Early appearance of sensitized lymphocytes in mice infected with Listeria monocytogenes.", "content": "Early appearance of sensitized lymphocytes in mice infected with Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205204"} {"pmid": "4205205", "title": "Polyribitol-phosphate: an antigen of four gram-positive bacteria cross-reactive with the capsular polysaccharide of haemophilus influenzae type B.", "content": "Polyribitol-phosphate: an antigen of four gram-positive bacteria cross-reactive with the capsular polysaccharide of haemophilus influenzae type B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205205"} {"pmid": "4205206", "title": "The role of T lymphocytes in the primary humoral antibody response to brucellin.", "content": "The role of T lymphocytes in the primary humoral antibody response to brucellin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205206"} {"pmid": "4205207", "title": "Activation of the classic and alternate complement pathways by endotoxin.", "content": "Activation of the classic and alternate complement pathways by endotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205207"} {"pmid": "4205208", "title": "Cytotoxic antibodies and lymphocytes induced by orthotopic tooth bud allografts in mice.", "content": "Cytotoxic antibodies and lymphocytes induced by orthotopic tooth bud allografts in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205208"} {"pmid": "4205209", "title": "Interaction of complement with antigen-antibody complexes of rabbit allotypic antigens and their corresponding antibodies.", "content": "Interaction of complement with antigen-antibody complexes of rabbit allotypic antigens and their corresponding antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205209"} {"pmid": "4205210", "title": "Immunosuppressive effects of anti-lymphocyte serum in complement deficient mice. II. Evidence that activity is mediated by C3 independent antibodies.", "content": "Immunosuppressive effects of anti-lymphocyte serum in complement deficient mice. II. Evidence that activity is mediated by C3 independent antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205210"} {"pmid": "4205213", "title": "Hypothalamic input to supraoptic neurons.", "content": "Hypothalamic input to supraoptic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205213"} {"pmid": "4205214", "title": "Grey's Hospital: the oldest hospital on its original site in the Republic.", "content": "Grey's Hospital: the oldest hospital on its original site in the Republic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205214"} {"pmid": "4205217", "title": "Immunofluorescent demonstration of bacterial antigen in experimental pyelonephritis with antiserum against common enterobacterial antigen.", "content": "Immunofluorescent demonstration of bacterial antigen in experimental pyelonephritis with antiserum against common enterobacterial antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205217"} {"pmid": "4205227", "title": "A new federal financial formula: an interview with the Minister of National Health and Welfare.", "content": "A new federal financial formula: an interview with the Minister of National Health and Welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205227"} {"pmid": "4205228", "title": "Psychiatric care of the disadvantaged child in a private practice setting.", "content": "Psychiatric care of the disadvantaged child in a private practice setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205228"} {"pmid": "4205229", "title": "Suppressive effect of concurrent administration of metal salts on carcinogenesis by 3'-methyl-4-(dimethylamino)azobenzene, and the effect of these metals on aminoazo dye metabolism during carcinogenesis.", "content": "Suppressive effect of concurrent administration of metal salts on carcinogenesis by 3'-methyl-4-(dimethylamino)azobenzene, and the effect of these metals on aminoazo dye metabolism during carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205229"} {"pmid": "4205230", "title": "Disturbance of immune system in mice by administration of 7,12-dimethylbenz(a)anthracene and normal thymocytes.", "content": "Disturbance of immune system in mice by administration of 7,12-dimethylbenz(a)anthracene and normal thymocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205230"} {"pmid": "4205240", "title": "Growth of the blue-green alga Tolypothrix tenuis as affected by cobalt and molybdenum.", "content": "Growth of the blue-green alga Tolypothrix tenuis as affected by cobalt and molybdenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205240"} {"pmid": "4205241", "title": "Effect of copper on the composition of bacterial cell wall peptides.", "content": "Effect of copper on the composition of bacterial cell wall peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205241"} {"pmid": "4205242", "title": "Production of bacterial amylase on some commercial materials.", "content": "Production of bacterial amylase on some commercial materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205242"} {"pmid": "4205243", "title": "Optimal conditions for production of bacterial amylase.", "content": "Optimal conditions for production of bacterial amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205243"} {"pmid": "4205244", "title": "Relationship between soybean cultivars and Rhizobium japonicum serotypes with single- and multi-strain inoculants. I. Greenhouse pot experiments.", "content": "Relationship between soybean cultivars and Rhizobium japonicum serotypes with single- and multi-strain inoculants. I. Greenhouse pot experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205244"} {"pmid": "4205245", "title": "Further investigations on hydroxyproline excretion in bovine puerperal paresis.", "content": "Further investigations on hydroxyproline excretion in bovine puerperal paresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205245"} {"pmid": "4205247", "title": "The influence of selenium administration on copper levels and growth of lambs.", "content": "The influence of selenium administration on copper levels and growth of lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205247"} {"pmid": "4205248", "title": "On the biometry of spermatozoa from different levels of the reproductive tract of buffalo bulls.", "content": "On the biometry of spermatozoa from different levels of the reproductive tract of buffalo bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205248"} {"pmid": "4205249", "title": "A kininogen-kinin like reaction revealed by the marginal distance of the equine lung.", "content": "A kininogen-kinin like reaction revealed by the marginal distance of the equine lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205249"} {"pmid": "4205250", "title": "Histological and histoenzymochemical aspects of ocular tumours in cattle.", "content": "Histological and histoenzymochemical aspects of ocular tumours in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205250"} {"pmid": "4205259", "title": "Cysts of the spinal ganglia.", "content": "Cysts of the spinal ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205259"} {"pmid": "4205268", "title": "Laboratory animal anaesthesia.", "content": "Laboratory animal anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205268"} {"pmid": "4205269", "title": "New appraoch to save health care costs.", "content": "New appraoch to save health care costs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205269"} {"pmid": "4205267", "title": "Toxoplasmosis: an overview.", "content": "Toxoplasmosis: an overview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205267"} {"pmid": "4205270", "title": "Nonrheumatic valvular cardiac disease: a clinicopathologic survey of 27 different conditions causing valvular dysfunction.", "content": "Nonrheumatic valvular cardiac disease: a clinicopathologic survey of 27 different conditions causing valvular dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205270"} {"pmid": "4205276", "title": "Differential effects of chromonar and nitroglycerin on intramyocardial oxygen tension.", "content": "Differential effects of chromonar and nitroglycerin on intramyocardial oxygen tension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205276"} {"pmid": "4205277", "title": "Vaccinia virus morphogenesis: a comparison of virus-induced antigens and polypeptides.", "content": "Vaccinia virus morphogenesis: a comparison of virus-induced antigens and polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205277"} {"pmid": "4205278", "title": "A method of freeze-drying and fixing spermatozoa for electron microscopy.", "content": "A method of freeze-drying and fixing spermatozoa for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205278"} {"pmid": "4205283", "title": "The effect of diphosphonate on calcium phosphate crystallization in urine in vitro.", "content": "The effect of diphosphonate on calcium phosphate crystallization in urine in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205283"} {"pmid": "4205287", "title": "The kinetics of synthesis and degradation of aspartate aminotransferase isozymes in rat peripheral red blood cells during cytodifferentiation.", "content": "The kinetics of synthesis and degradation of aspartate aminotransferase isozymes in rat peripheral red blood cells during cytodifferentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205287"} {"pmid": "4205288", "title": "Blood group antigens I, i, H and HI on monkey, rabbit and guinea pig erythrocytes.", "content": "Blood group antigens I, i, H and HI on monkey, rabbit and guinea pig erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205288"} {"pmid": "4205289", "title": "The effect of intravenous hyperalimentation on erythrocyte lipids.", "content": "The effect of intravenous hyperalimentation on erythrocyte lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205289"} {"pmid": "4205290", "title": "Tyrosinase activity in a highly pigmented human melanoma and in negro skin.", "content": "Tyrosinase activity in a highly pigmented human melanoma and in negro skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205290"} {"pmid": "4205292", "title": "Prevention of microbial catheter contamination in patients receiving parenteral hyperalimentation.", "content": "Prevention of microbial catheter contamination in patients receiving parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205292"} {"pmid": "4205293", "title": "Primary reticulum cell sarcoma of the femur: 12-year follow-up after radiation therapy and pathologic fracture.", "content": "Primary reticulum cell sarcoma of the femur: 12-year follow-up after radiation therapy and pathologic fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205293"} {"pmid": "4205294", "title": "In vitro specificity and in vivo activity of antimacrophage serum.", "content": "In vitro specificity and in vivo activity of antimacrophage serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205294"} {"pmid": "4205296", "title": "On the levels of hemoglobins F and A2 in sickle-cell anemia and some related disorders.", "content": "On the levels of hemoglobins F and A2 in sickle-cell anemia and some related disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205296"} {"pmid": "4205297", "title": "Total balanced intravenous feeding by peripheral veins in paediatric surgery. A summary of 7 years' research and clinical experience.", "content": "Total balanced intravenous feeding by peripheral veins in paediatric surgery. A summary of 7 years' research and clinical experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205297"} {"pmid": "4205302", "title": "Insecticides, polychlorinated biphenyls and mercury in wild cormorants, pelicans, their eggs, food and environment.", "content": "Insecticides, polychlorinated biphenyls and mercury in wild cormorants, pelicans, their eggs, food and environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205302"} {"pmid": "4205301", "title": "Inhibition of microsomal drug metabolism by anticholinesterase insecticides.", "content": "Inhibition of microsomal drug metabolism by anticholinesterase insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205301"} {"pmid": "4205303", "title": "Uptake and accumulation of DDT and PCB by Ephemera danica (Ephemeroptera) in continuous-flow systems.", "content": "Uptake and accumulation of DDT and PCB by Ephemera danica (Ephemeroptera) in continuous-flow systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205303"} {"pmid": "4205304", "title": "Molybdenum toxicity: abnormal cellular division of teratogenic appearance in Euglena gracilis.", "content": "Molybdenum toxicity: abnormal cellular division of teratogenic appearance in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205304"} {"pmid": "4205305", "title": "Chlorinated hydrocarbons in plankton from the Gulf of Mexico and Northern Carribbean.", "content": "Chlorinated hydrocarbons in plankton from the Gulf of Mexico and Northern Carribbean.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205305"} {"pmid": "4205306", "title": "Discharge planning; an asset in the continuum of patient care services.", "content": "Discharge planning; an asset in the continuum of patient care services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205306"} {"pmid": "4205308", "title": "The HMO in perspective.", "content": "The HMO in perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205308"} {"pmid": "4205309", "title": "IgE and IgG antibodies against Aspergillus fumigatus in sera of patients with bronchopulmonary allergic aspergillosis.", "content": "IgE and IgG antibodies against Aspergillus fumigatus in sera of patients with bronchopulmonary allergic aspergillosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205309"} {"pmid": "4205310", "title": "Immuno- and physicochemical studies of an IgA-IgG mixed cryoglobulin.", "content": "Immuno- and physicochemical studies of an IgA-IgG mixed cryoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205310"} {"pmid": "4205311", "title": "Limb immobilization devices for chaired waking monkeys.", "content": "Limb immobilization devices for chaired waking monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205311"} {"pmid": "4205312", "title": "Industrial chemicals. Extraction of polychlorinated biphenyls: evaluation of a column technique applied to polar bear and seal tissue.", "content": "Industrial chemicals. Extraction of polychlorinated biphenyls: evaluation of a column technique applied to polar bear and seal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205312"} {"pmid": "4205313", "title": "Folate coenzymes of Lactobacillus casei and Streptococcus faecalis.", "content": "Folate coenzymes of Lactobacillus casei and Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205313"} {"pmid": "4205314", "title": "Kinetic mechanism of glycogen synthase D from human polymorphonuclear leukocytes.", "content": "Kinetic mechanism of glycogen synthase D from human polymorphonuclear leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205314"} {"pmid": "4205315", "title": "Homocysteine biosynthesis in green plants. O-Phosphorylhomoserine as the physiological substrate for cystathionine gamma-synthase.", "content": "Homocysteine biosynthesis in green plants. O-Phosphorylhomoserine as the physiological substrate for cystathionine gamma-synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205315"} {"pmid": "4205316", "title": "The carboxypeptidase-dependent inactivation of thymidylate synthetase.", "content": "The carboxypeptidase-dependent inactivation of thymidylate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205316"} {"pmid": "4205317", "title": "Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R. Biochemical and biophysical properties of methionine transfer ribonucleic acid.", "content": "Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R. Biochemical and biophysical properties of methionine transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205317"} {"pmid": "4205319", "title": "Separation of dihydroergotoxine (hydergine) into dihydroergocornine, dihydroergocryptine and dihydroergocristine by counter-current distribution.", "content": "Separation of dihydroergotoxine (hydergine) into dihydroergocornine, dihydroergocryptine and dihydroergocristine by counter-current distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205319"} {"pmid": "4205318", "title": "Studies of membrane formation in Tetrahymena pyriformis. The biosynthesis of proteins and their assembly into membranes of growing cells.", "content": "Studies of membrane formation in Tetrahymena pyriformis. The biosynthesis of proteins and their assembly into membranes of growing cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205318"} {"pmid": "4205320", "title": "Functional localization in the trigeminal root.", "content": "Functional localization in the trigeminal root.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205320"} {"pmid": "4205321", "title": "Whirlpool therapy for the treatment of soft tissue wounds complicating extremity fractures.", "content": "Whirlpool therapy for the treatment of soft tissue wounds complicating extremity fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205321"} {"pmid": "4205322", "title": "Letter: Urethritis at a regional VD clinic.", "content": "Letter: Urethritis at a regional VD clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205322"} {"pmid": "4205324", "title": "Cryosurgery of respiratory structures. II. Cryonecrosis of the lung.", "content": "Cryosurgery of respiratory structures. II. Cryonecrosis of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205324"} {"pmid": "4205325", "title": "Another generation gap: physicians vs. the elderly.", "content": "Another generation gap: physicians vs. the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205325"} {"pmid": "4205326", "title": "Low dose prophylactic antibiotics in vaginal hysterectomy.", "content": "Low dose prophylactic antibiotics in vaginal hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205326"} {"pmid": "4205327", "title": "The effect of anticoagulants on the dialysis method of measurement of vitamin B 12 binding capacity of plasma proteins.", "content": "The effect of anticoagulants on the dialysis method of measurement of vitamin B 12 binding capacity of plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205327"} {"pmid": "4205329", "title": "Diagnosis and incidence of Neisseria gonorrhoeae in Cape coloured females in the Western Cape. Laboratory aspects.", "content": "Diagnosis and incidence of Neisseria gonorrhoeae in Cape coloured females in the Western Cape. Laboratory aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205329"} {"pmid": "4205336", "title": "Metabolism of 14C-histamine in amphibians (Bufo bufo) and reptiles (Pseudemys scripta and Testudo hermanni).", "content": "Metabolism of 14C-histamine in amphibians (Bufo bufo) and reptiles (Pseudemys scripta and Testudo hermanni).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205336"} {"pmid": "4205337", "title": "Application of Cu(II) ions for an indicator reaction in volumetric methods of drug assay. VI. Quantitative determination of the active substance in spasmophen and spasmophen-duplex.", "content": "Application of Cu(II) ions for an indicator reaction in volumetric methods of drug assay. VI. Quantitative determination of the active substance in spasmophen and spasmophen-duplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205337"} {"pmid": "4205338", "title": "A comparison of retinal argon laser lesions in man and in cynomolgus monkey.", "content": "A comparison of retinal argon laser lesions in man and in cynomolgus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205338"} {"pmid": "4205340", "title": "Double-mind theory.", "content": "Double-mind theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205340"} {"pmid": "4205349", "title": "Primary dietary prevention of atherosclerosis.", "content": "Primary dietary prevention of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205349"} {"pmid": "4205350", "title": "Hospital food and possibilities of its improvement. Clinical aspects.", "content": "Hospital food and possibilities of its improvement. Clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205350"} {"pmid": "4205351", "title": "Biosynthesis of immunoglobulin A (IgA). Secretion and addition of carbohydrate to monomer and polymer forms of a mouse myeloma protein.", "content": "Biosynthesis of immunoglobulin A (IgA). Secretion and addition of carbohydrate to monomer and polymer forms of a mouse myeloma protein. Cell suspensions of mouse plasma-cell tumour MOPC 315 secreting predominantly IgA (immunoglobulin A) monomer and dimer were incubated with radioactive leucine, mannose, galactose and fucose for various periods of time. The amounts of secreted and intracellular immunoglobulins were measured by co-precipitation with specific antibody, and the molecular species present were assessed by electrophoresis in polyacrylamide gels. Analysis of the secreted myeloma protein demonstrated that monomer and dimer IgA molecules are identical with respect to carbohydrate composition and rate of secretion. Within the cell, the myeloma protein is almost entirely accounted for by monomer units which either leave the cell as such or are polymerized with the addition of J chain close to the time of secretion. The results support the concept of a stepwise addition of carbohydrate residues to IgA immunoglobulin during the process of secretion. Similar patterns of carbohydrate assembly were found for the monomer or dimer molecules. Mannose residues are added at an early stage, whereas fucose is added close to the time of secretion. Galactose is also added early, but some may also be incorporated at a later stage. Control of IgA polymerization is considered unlikely to reflect regulation at the level of carbohydrate addition, and it is suggested that the critical controlling factor is the J chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205351"} {"pmid": "4205344", "title": "Type-A influenza viruses isolated from wild free-flying ducks in California.", "content": "Type-A influenza viruses isolated from wild free-flying ducks in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205344"} {"pmid": "4205353", "title": "Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Control of polymerization by J chain.", "content": "Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Control of polymerization by J chain. Cell suspensions of mouse plasma-cell tumours secreting IgA (immunoglobulin A) and IgM (immunoglobulin M) were incubated with radioactive leucine for various periods of time. The secreted immunoglobulins were precipitated from the culture medium with specific rabbit antisera to determine the relative distribution of radioactivity among the different molecular species, and to estimate the fraction of total radioactivity in the J chain. For IgM-secreting cells there is a balanced synthesis of 7S subunits and J chains, and the secreted product is uniformly assembled to the pentamer. In cells secreting IgA, however, the results demonstrate that the pool of intracellular J chain is less than the intracellular IgA pool. The concentration of J chain is therefore limiting and is less than the requirement for complete polymerization. The major factor that determines whether an intracellular monomer is secreted as such or is polymerized with the addition of J chain is therefore the amount of intracellular J chain. When this is limiting, as it is in cells secreting IgA, then monomer will be secreted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205353"} {"pmid": "4205352", "title": "Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Requirement for J chain and a disulphide-exchanging enzyme for polymerization.", "content": "Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Requirement for J chain and a disulphide-exchanging enzyme for polymerization. Mouse myeloma cells secreting 19S IgM (immunoglobulin M) (MOPC 104E and TEPC 183) or monomer and polymer IgA (immunoglobulin A) (MOPC 315) were incubated with radioactive leucine and the intracellular and secreted immunoglobulins and immunoglobulin subunits were prepared by preparative sucrose-density-gradient centrifugation. Samples were reduced in the presence or absence of isolated J chain, passed over Sephadex G-25 and then incubated at 37 degrees C for 30min with or without a source of disulphide-interchange enzyme. The extent of reassembly of reduced subunits was then evaluated by electrophoresis in polyacrylamide gels. Provided that J chain and the disulphide-interchange enzyme were supplied, both IgM and IgA could be assembled from their respective subunits, obtained by reductive cleavage of polymeric forms. Under similar conditions, assembly of polymeric forms from intracellular or secreted 7S monomer subunits also occurred. Under these conditions polymerization was total, there being no residue of the monomeric form. Reassembly did not occur in the absence of either J chain or the enzyme. All of the J chain released from IgM by reductive cleavage was incorporated back into the reassembled polymer. The J chain is therefore likely to be an essential structural requirement for polymeric immunoglobulins. A variety of controls ruled out non-specific interactions, and further suggested that the amino acid sequence of polypeptide chains determines the specificity of polymerization. The fact that intracellular IgA and IgM monomer subunits known to be deficient in galactose and fucose can be completely polymerized suggests that the addition of carbohydrate does not control polymerization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205352"} {"pmid": "4205354", "title": "Effect of methylglyoxal bis(guanylhydrazone) on polyamine metabolism in normal and regenerating rat liver and rat thymus.", "content": "Effect of methylglyoxal bis(guanylhydrazone) on polyamine metabolism in normal and regenerating rat liver and rat thymus. 1. Injections of sublethal doses of methylglyoxal bis(guanylhydrazone), a potent inhibitor of putrescine-activated S-adenosylmethionine decarboxylase in vitro, resulted after a few days in an immense increase in the activity of S-adenosylmethionine decarboxylase in normal and regenerating rat liver and in rat thymus. The increase in the activity of S-adenosylmethionine decarboxylase was at least partly due to a marked lengthening of the half-life of the enzyme. 2. In regenerating liver and thymus there was also a moderate stimulation of the activity of ornithine decarboxylase (EC 4.1.1.17) and a marked accumulation of tissue putrescine. 3. Injection of methylglyoxal bis(guanylhydrazone) into the rat also markedly decreased the activity of diamine oxidase (EC 1.4.3.6) in thymus. 4. In no cases where doses of methylglyoxal bis(guanylhydrazone) close to the LD(50) dose for the rat were used was it possible to lower tissue spermidine content to any significant extent. 5. Methylglyoxal bis(guanylhydrazone) seemed to act as a competitive inhibitor for the substrate S-adenosylmethionine and as an uncompetitive inhibitor for the activator putrescine in the decarboxylation of S-adenosylmethionine in vitro. 6. In the diamine oxidase reaction, with putrescine as the substrate, methylglyoxal bis(guanylhydrazone) was a non-competitive inhibitor for putrescine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205354"} {"pmid": "4205347", "title": "A comparison of the prophylactic efficacy of lyophilized and cell-associated turkey herpesvirus against Marek's disease.", "content": "A comparison of the prophylactic efficacy of lyophilized and cell-associated turkey herpesvirus against Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205347"} {"pmid": "4205348", "title": "Effects of Eimeria acervulina on intestinal pH in conventional and gnotobiotic chickens.", "content": "Effects of Eimeria acervulina on intestinal pH in conventional and gnotobiotic chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205348"} {"pmid": "4205345", "title": "Pathology and prevention of Leucocytozoon smithi infection of Turkeys.", "content": "Pathology and prevention of Leucocytozoon smithi infection of Turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205345"} {"pmid": "4205357", "title": "Varying persistence of polychlorinated biphenyls in six California soils under laboratory conditions.", "content": "Varying persistence of polychlorinated biphenyls in six California soils under laboratory conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205357"} {"pmid": "4205358", "title": "A search for polychlorinated biphenyls in human milk in rural Colorado.", "content": "A search for polychlorinated biphenyls in human milk in rural Colorado.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205358"} {"pmid": "4205360", "title": "Effects of pH, light and temperature on carbaryl in aqueous media.", "content": "Effects of pH, light and temperature on carbaryl in aqueous media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205360"} {"pmid": "4205346", "title": "Immunization against Marek's disease: influence of strain of chickens, maternal antibody, and type of vaccine.", "content": "Immunization against Marek's disease: influence of strain of chickens, maternal antibody, and type of vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205346"} {"pmid": "4205361", "title": "Embryotoxic effects of three PCB'S in the chicken.", "content": "Embryotoxic effects of three PCB'S in the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205361"} {"pmid": "4205359", "title": "Tests of pesticidal synergism with young pheasants and Japanese quail.", "content": "Tests of pesticidal synergism with young pheasants and Japanese quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205359"} {"pmid": "4205362", "title": "PCB and hydrocarbon contamination of plankton by nets.", "content": "PCB and hydrocarbon contamination of plankton by nets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205362"} {"pmid": "4205363", "title": "A qualitative method for detecting hydroxylated metabolites of polychlorinated biphenyls.", "content": "A qualitative method for detecting hydroxylated metabolites of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205363"} {"pmid": "4205364", "title": "Outer (cell wall) membrane proteins of Pseudomonas aeruginosa.", "content": "Outer (cell wall) membrane proteins of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205364"} {"pmid": "4205366", "title": "\"Whither medicine in Rhodesia\".", "content": "\"Whither medicine in Rhodesia\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205366"} {"pmid": "4205365", "title": "Demonstration of delayed hypersensitivity to Neisseria meningitidis.", "content": "Demonstration of delayed hypersensitivity to Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205365"} {"pmid": "4205367", "title": "New thoughts for old. II.", "content": "New thoughts for old. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205367"} {"pmid": "4205368", "title": "Comparison of preparations of erythrocyte membranes and membrane proteins by SDS-gel electrophoresis.", "content": "Comparison of preparations of erythrocyte membranes and membrane proteins by SDS-gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205368"} {"pmid": "4205369", "title": "Precipitating antibody against core glycolipid of Enterobacteriaceae.", "content": "Precipitating antibody against core glycolipid of Enterobacteriaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205369"} {"pmid": "4205370", "title": "Orosomucoid, seromucoid and haptoglobin in serum during adjuvant arthritis of the rat.", "content": "Orosomucoid, seromucoid and haptoglobin in serum during adjuvant arthritis of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205370"} {"pmid": "4205371", "title": "Intracavitary electron beam therapy for cancer of the uterine cervix: dose-distribution study and clinical result.", "content": "Intracavitary electron beam therapy for cancer of the uterine cervix: dose-distribution study and clinical result.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205371"} {"pmid": "4205373", "title": "Letter: Susceptibility to damage from impulse noise: chinchilla versus man or monkey.", "content": "Letter: Susceptibility to damage from impulse noise: chinchilla versus man or monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205373"} {"pmid": "4205372", "title": "Parenteral hyperalimentation in gynecologic oncology patients.", "content": "Parenteral hyperalimentation in gynecologic oncology patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205372"} {"pmid": "4205374", "title": "Antimetabolites produced by microorganisms. VII. L-(N5-phosphono)methionine-S-sulfoximinyl-L-alanyl-L-alanine.", "content": "Antimetabolites produced by microorganisms. VII. L-(N5-phosphono)methionine-S-sulfoximinyl-L-alanyl-L-alanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205374"} {"pmid": "4205375", "title": "Studies on the antiviral substance. Mechanism of action of bihoromycin, a new antibiotic.", "content": "Studies on the antiviral substance. Mechanism of action of bihoromycin, a new antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205375"} {"pmid": "4205376", "title": "Fluorescence studies on the interaction between heavy meromyosin and magnesium ions. Effect of EDTA.", "content": "Fluorescence studies on the interaction between heavy meromyosin and magnesium ions. Effect of EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205376"} {"pmid": "4205377", "title": "Ionic changes during smooth muscle fixation for electron microscopy.", "content": "Ionic changes during smooth muscle fixation for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205377"} {"pmid": "4205418", "title": "Identification and localization of intraarticular colloidal gold: ultrastructural and electron microprobe examinations of human biopsies.", "content": "Identification and localization of intraarticular colloidal gold: ultrastructural and electron microprobe examinations of human biopsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205418"} {"pmid": "4205419", "title": "The reticulum cell and the reticular cell in the mouse popliteal lymph node. An electron microscopic autoradiographic study.", "content": "The reticulum cell and the reticular cell in the mouse popliteal lymph node. An electron microscopic autoradiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205419"} {"pmid": "4205420", "title": "Nephritogenic properties of nephrotoxic guinea pig antibodies. II. Glomerular lesions induced by F(ab')2 fragments of nephrotoxic IgG1 antibody in rats.", "content": "Nephritogenic properties of nephrotoxic guinea pig antibodies. II. Glomerular lesions induced by F(ab')2 fragments of nephrotoxic IgG1 antibody in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205420"} {"pmid": "4205424", "title": "Effect of heparin, histamine and serotonin on the density-dependent inhibition of replication in two fibroblastic cell lines.", "content": "Effect of heparin, histamine and serotonin on the density-dependent inhibition of replication in two fibroblastic cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205424"} {"pmid": "4205417", "title": "Hunger and satiety in humans during parenteral hyperalimentation.", "content": "Hunger and satiety in humans during parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205417"} {"pmid": "4205430", "title": "Letter: Rhesus prophylaxis after twin delivery.", "content": "Letter: Rhesus prophylaxis after twin delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205430"} {"pmid": "4205431", "title": "Kotonkan, a new rhabdovirus related to Mokola virus of the rabies serogroup.", "content": "Kotonkan, a new rhabdovirus related to Mokola virus of the rabies serogroup.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205431"} {"pmid": "4205432", "title": "Infectivity of sputum-positive tuberculous patients on chemotherapy.", "content": "Infectivity of sputum-positive tuberculous patients on chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205432"} {"pmid": "4205433", "title": "Routine diagnosis of tuberculosis with phase-contrast microscopy.", "content": "Routine diagnosis of tuberculosis with phase-contrast microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205433"} {"pmid": "4205434", "title": "Letter: Selective inhibition of phagocytic activity of rabbit alveolar macrophages by cystic fibrosis serum.", "content": "Letter: Selective inhibition of phagocytic activity of rabbit alveolar macrophages by cystic fibrosis serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205434"} {"pmid": "4205436", "title": "An electron microscopic observation of the nucleolar material attached to the chromosomes of HeLa cells in metaphase.", "content": "An electron microscopic observation of the nucleolar material attached to the chromosomes of HeLa cells in metaphase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205436"} {"pmid": "4205435", "title": "Osmium impregnation of methyl methacrylate vascular casts for scanning electron microscopy.", "content": "Osmium impregnation of methyl methacrylate vascular casts for scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205435"} {"pmid": "4205441", "title": "Microbial degradation of DDT metabolites to carbon dioxide, water, and chloride.", "content": "Microbial degradation of DDT metabolites to carbon dioxide, water, and chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205441"} {"pmid": "4205443", "title": "Effects of sodium arsenite on fetal development.", "content": "Effects of sodium arsenite on fetal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205443"} {"pmid": "4205442", "title": "Polychlorinated terphenyls in the environment.", "content": "Polychlorinated terphenyls in the environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205442"} {"pmid": "4205444", "title": "Chlorinated hydrocarbon residues in marine animals of southern California.", "content": "Chlorinated hydrocarbon residues in marine animals of southern California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205444"} {"pmid": "4205445", "title": "Similarity of a polychlorinated biphenyl (Aroclor 1254) and DDE in rate of elimination from cows.", "content": "Similarity of a polychlorinated biphenyl (Aroclor 1254) and DDE in rate of elimination from cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205445"} {"pmid": "4205446", "title": "Improved procedures for the determination of oxytetracycline in milk, milk products; chicken muscle, liver; and eggs.", "content": "Improved procedures for the determination of oxytetracycline in milk, milk products; chicken muscle, liver; and eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205446"} {"pmid": "4205447", "title": "Discrimination between PCB and DDT residues by a gas chromatographic-mass spectrometric technique.", "content": "Discrimination between PCB and DDT residues by a gas chromatographic-mass spectrometric technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205447"} {"pmid": "4205448", "title": "Polychlorinated biphenyls: photolysis of 3, 4, 3', 4'-tetrachlorobiphenyl and 4, 4'-dichlorobiphenyl in solution.", "content": "Polychlorinated biphenyls: photolysis of 3, 4, 3', 4'-tetrachlorobiphenyl and 4, 4'-dichlorobiphenyl in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205448"} {"pmid": "4205449", "title": "Acute intraperitoneal toxicity of DDT and PCB's in mice using two solvents.", "content": "Acute intraperitoneal toxicity of DDT and PCB's in mice using two solvents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205449"} {"pmid": "4205450", "title": "The malignant transformation as a metabolic steady state transition: the possible significance of the phasing of enzyme synthesis and related aspects.", "content": "The malignant transformation as a metabolic steady state transition: the possible significance of the phasing of enzyme synthesis and related aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205450"} {"pmid": "4205451", "title": "An investigation of the aetiology of the 1966 outbreak of febrile illness in Jabalpur, Madhya Pradesh.", "content": "An investigation of the aetiology of the 1966 outbreak of febrile illness in Jabalpur, Madhya Pradesh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205451"} {"pmid": "4205452", "title": "Preliminary studies of body potassium in normal adults by whole body counter.", "content": "Preliminary studies of body potassium in normal adults by whole body counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205452"} {"pmid": "4205453", "title": "Vital signs in progressive intracranial hypertension: an experimental study.", "content": "Vital signs in progressive intracranial hypertension: an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205453"} {"pmid": "4205454", "title": "Susceptibility of N. gonorrhoeae in vitro to antibiotics (penicillin, oxytetracycline, chloramphenicol and rifampicin).", "content": "Susceptibility of N. gonorrhoeae in vitro to antibiotics (penicillin, oxytetracycline, chloramphenicol and rifampicin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205454"} {"pmid": "4205455", "title": "Use of isotopic abundance ratios in identification of polychlorinated biphenyls by mass spectrometry.", "content": "Use of isotopic abundance ratios in identification of polychlorinated biphenyls by mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205455"} {"pmid": "4205457", "title": "Inhibition of lipid biosynthesis by p-chlorophenoxy-isobutyrate (CPIB) in Tetrahymena pyriformis.", "content": "Inhibition of lipid biosynthesis by p-chlorophenoxy-isobutyrate (CPIB) in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205457"} {"pmid": "4205456", "title": "Antigenic properties of some insects involved in food contamination.", "content": "Antigenic properties of some insects involved in food contamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205456"} {"pmid": "4205458", "title": "Studies on ion transport in cells of photosynthetic bacteria. I. The key role of anions in determining the direction and magnitude of hydrogen ion flux.", "content": "Studies on ion transport in cells of photosynthetic bacteria. I. The key role of anions in determining the direction and magnitude of hydrogen ion flux.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205458"} {"pmid": "4205459", "title": "Studies on ion transport in cells of photosynthetic bacteria. II. Analysis of reversed hydrogen ion change.", "content": "Studies on ion transport in cells of photosynthetic bacteria. II. Analysis of reversed hydrogen ion change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205459"} {"pmid": "4205460", "title": "Studies on ion transport in cells of photosynthetic bacteria. 3. The influence of uncouplers on hydrogen ion change.", "content": "Studies on ion transport in cells of photosynthetic bacteria. 3. The influence of uncouplers on hydrogen ion change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205460"} {"pmid": "4205461", "title": "The characteristic action patterns of crystalline bacterial saccharifying alpha-amylase independent of its microheterogeneity.", "content": "The characteristic action patterns of crystalline bacterial saccharifying alpha-amylase independent of its microheterogeneity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205461"} {"pmid": "4205462", "title": "Competition between Pi and pH indicators in photosynthetic ATP formation in chromatophores of Rhodospirillum rubrum.", "content": "Competition between Pi and pH indicators in photosynthetic ATP formation in chromatophores of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205462"} {"pmid": "4205463", "title": "Effects of ventral putamen lesions on discrimination learning by monkeys.", "content": "Effects of ventral putamen lesions on discrimination learning by monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205463"} {"pmid": "4205464", "title": "Carrier rate of Neisseria meningitidis and the occurrence of sulfonamide resistant strains in Lebanon.", "content": "Carrier rate of Neisseria meningitidis and the occurrence of sulfonamide resistant strains in Lebanon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205464"} {"pmid": "4205465", "title": "A study of passive potassium efflux from human red blood cells using ion-specific electrodes.", "content": "A study of passive potassium efflux from human red blood cells using ion-specific electrodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205465"} {"pmid": "4205466", "title": "The penetration of water into the epithelium of toad urinary bladder and its modification by oxytocin.", "content": "The penetration of water into the epithelium of toad urinary bladder and its modification by oxytocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205466"} {"pmid": "4205467", "title": "An analysis of the relationship between the current and potential generated by a quantum of acetylcholine in muscle fibers without transverse tubules.", "content": "An analysis of the relationship between the current and potential generated by a quantum of acetylcholine in muscle fibers without transverse tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205467"} {"pmid": "4205469", "title": "A new myxosporidan in red and golden shiners.", "content": "A new myxosporidan in red and golden shiners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205469"} {"pmid": "4205468", "title": "Effect of antiserum on maltase from intestinal microvillous membranes of Ascaris suum.", "content": "Effect of antiserum on maltase from intestinal microvillous membranes of Ascaris suum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205468"} {"pmid": "4205470", "title": "An evaluation of the direct agglutination test for Chagas' disease.", "content": "An evaluation of the direct agglutination test for Chagas' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205470"} {"pmid": "4205471", "title": "Significance of intimal arterial changes in non-human vertebrates.", "content": "Significance of intimal arterial changes in non-human vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205471"} {"pmid": "4205472", "title": "Physiologic and clinical actions of nitroglycerin.", "content": "Physiologic and clinical actions of nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205472"} {"pmid": "4205473", "title": "Diagnosis of angina pectoris at the present time.", "content": "Diagnosis of angina pectoris at the present time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205473"} {"pmid": "4205476", "title": "Diabetes mellitus. New developments.", "content": "Diabetes mellitus. New developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205476"} {"pmid": "4205480", "title": "The etiology and pathogenesis of osteoarthrosis: a review.", "content": "The etiology and pathogenesis of osteoarthrosis: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205480"} {"pmid": "4205481", "title": "Long-term toxicity study of methylmercuric chloride in monkeys (first report).", "content": "Long-term toxicity study of methylmercuric chloride in monkeys (first report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205481"} {"pmid": "4205487", "title": "Competitive inhibition between oxytocin and luteinizing hormone-releasing factor (LRF) for the same enzyme system in the rat hypothalamus.", "content": "Competitive inhibition between oxytocin and luteinizing hormone-releasing factor (LRF) for the same enzyme system in the rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205487"} {"pmid": "4205488", "title": "Some factors influencing TRH bioassay in mice.", "content": "Some factors influencing TRH bioassay in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205488"} {"pmid": "4205489", "title": "Rapid estimation of human chorionic somatomammotrophin (HCS) by haemagglutination inhibition and comparison of results with radioimmunoassay.", "content": "Rapid estimation of human chorionic somatomammotrophin (HCS) by haemagglutination inhibition and comparison of results with radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205489"} {"pmid": "4205490", "title": "Influence of oophorectomy, luteectomy, foetal death and dexamethasone on the peripheral plasma levels of oestrogens and progesterone in the pregnant Macaca mulatta.", "content": "Influence of oophorectomy, luteectomy, foetal death and dexamethasone on the peripheral plasma levels of oestrogens and progesterone in the pregnant Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205490"} {"pmid": "4205491", "title": "Nitrogen-15 studies of erythropoiesis during recovery from marasmus.", "content": "Nitrogen-15 studies of erythropoiesis during recovery from marasmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205491"} {"pmid": "4205492", "title": "Vitamins A and E nutrition via intramuscular or oral route.", "content": "Vitamins A and E nutrition via intramuscular or oral route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205492"} {"pmid": "4205494", "title": "Effects of protein-calorie malnutrition on the jejunal mucosa of tetracycline-treated pigs.", "content": "Effects of protein-calorie malnutrition on the jejunal mucosa of tetracycline-treated pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205494"} {"pmid": "4205497", "title": "Cerebral arterial occlusion and cluster headaches in neurofibromatosis.", "content": "Cerebral arterial occlusion and cluster headaches in neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205497"} {"pmid": "4205496", "title": "Red blood cell beta-aminolevulinic acid dehydrase activity. An index of body lead burden.", "content": "Red blood cell beta-aminolevulinic acid dehydrase activity. An index of body lead burden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205496"} {"pmid": "4205500", "title": "Letter: Pseudomonas infections.", "content": "Letter: Pseudomonas infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205500"} {"pmid": "4205495", "title": "Infant and child enteritis-malabsorption-malnutrition: the potential of limited studies with low-dose antibiotic feeding.", "content": "Infant and child enteritis-malabsorption-malnutrition: the potential of limited studies with low-dose antibiotic feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205495"} {"pmid": "4205501", "title": "Letter: What is meant by \"bimonthly\"?", "content": "Letter: What is meant by \"bimonthly\"?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205501"} {"pmid": "4205493", "title": "Plasma and red cell water and elements in protein-calorie malnutrition.", "content": "Plasma and red cell water and elements in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205493"} {"pmid": "4205499", "title": "Immunofluorescent studies in mucous membrane pemphigoid.", "content": "Immunofluorescent studies in mucous membrane pemphigoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205499"} {"pmid": "4205498", "title": "Bacteraemia as a complication of subclavian vein catheterisation.", "content": "Bacteraemia as a complication of subclavian vein catheterisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205498"} {"pmid": "4205502", "title": "Letter: Gold treatment of pemphigus.", "content": "Letter: Gold treatment of pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205502"} {"pmid": "4205504", "title": "Editorial: Hereditary eye disease and prenatal diagnosis.", "content": "Editorial: Hereditary eye disease and prenatal diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205504"} {"pmid": "4205503", "title": "Laboratory diagnosis of increased lead absorption.", "content": "Laboratory diagnosis of increased lead absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205503"} {"pmid": "4205505", "title": "Electrophysiological and psychophysical findings in Hunter syndrome.", "content": "Electrophysiological and psychophysical findings in Hunter syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205505"} {"pmid": "4205507", "title": "Column chromatographic separation of polychlorinated biphenyls from chlorinated hydrocarbon pesticides, and their subsequent gas chromatographic quantitation in terms of derivatives.", "content": "Column chromatographic separation of polychlorinated biphenyls from chlorinated hydrocarbon pesticides, and their subsequent gas chromatographic quantitation in terms of derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205507"} {"pmid": "4205508", "title": "A general method for the preparation of tritiated polychlorobiphenyls of high specific activity: 2,2',5,5'-tetrachlorobiphenyl-(3H) and 2,2',4,4',5,5'-hexachlorobiphenyl-(3H).", "content": "A general method for the preparation of tritiated polychlorobiphenyls of high specific activity: 2,2',5,5'-tetrachlorobiphenyl-(3H) and 2,2',4,4',5,5'-hexachlorobiphenyl-(3H).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205508"} {"pmid": "4205509", "title": "Separation of aldrin from Aroclor 1254.", "content": "Separation of aldrin from Aroclor 1254.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205509"} {"pmid": "4205511", "title": "Mirex residues in wild populations of the edible red crawfish (Procambarus clarki).", "content": "Mirex residues in wild populations of the edible red crawfish (Procambarus clarki).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205511"} {"pmid": "4205510", "title": "PCB residues in Atlantic zooplankton.", "content": "PCB residues in Atlantic zooplankton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205510"} {"pmid": "4205512", "title": "The extended care philosophy: A must for the long-term patient.", "content": "The extended care philosophy: A must for the long-term patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205512"} {"pmid": "4205513", "title": "Tumor-associated antigen(s) from granulosa cell carcinomas of the ovary.", "content": "Tumor-associated antigen(s) from granulosa cell carcinomas of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205513"} {"pmid": "4205516", "title": "Factors influencing admission and discharge from a hospital for the chronic sick in Israel.", "content": "Factors influencing admission and discharge from a hospital for the chronic sick in Israel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205516"} {"pmid": "4205515", "title": "A survey of pulmonary tuberculosis in the elderly in North Staffordshire.", "content": "A survey of pulmonary tuberculosis in the elderly in North Staffordshire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205515"} {"pmid": "4205514", "title": "Treatment of streptococcal pharyngitis with different antibiotic regimens.", "content": "Treatment of streptococcal pharyngitis with different antibiotic regimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205514"} {"pmid": "4205506", "title": "Serum levels of C1q, C1r and C1s in normal and pathologic sera.", "content": "Serum levels of C1q, C1r and C1s in normal and pathologic sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205506"} {"pmid": "4205517", "title": "The changing pattern of geriatric care. A 20-year survey report from the West Cornwall clinical area.", "content": "The changing pattern of geriatric care. A 20-year survey report from the West Cornwall clinical area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205517"} {"pmid": "4205520", "title": "Collaborative study of the recovery and gas chromatographic quantitation of polychlorinated biphenyls in chicken fat and polychlorinated biphenyl-DDT combinations in fish.", "content": "Collaborative study of the recovery and gas chromatographic quantitation of polychlorinated biphenyls in chicken fat and polychlorinated biphenyl-DDT combinations in fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205520"} {"pmid": "4205521", "title": "Polychlorinated biphenyls and polychlorinated terphenyls in Canadian food packaging materials.", "content": "Polychlorinated biphenyls and polychlorinated terphenyls in Canadian food packaging materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205521"} {"pmid": "4205522", "title": "A serum component related to nonimmunoglobulin amyloid protein AS, a possible precursor of the fibrils.", "content": "A serum component related to nonimmunoglobulin amyloid protein AS, a possible precursor of the fibrils. A nonimmunoglobulin protein with the molecular weight of 9,145 (protein AS) has been shown to be a principal component of the amyloid fibrils in different clinical types of amyloidosis. A protein component, antigenically closely related to protein AS, was detected in human sera. The protein AS-related component (protein ASC) was found in the sera of many groups of patients, including 48 out of 55 patients with various clinical types of amyloidosis. No structural relationship of protein ASC to the plasma component of amyloid was found. Protein ASC was also present with high frequency in the serum of diseases known to be frequently complicated by amyloidosis. In some cases, ASC was found in the sera of patients 2-3 yr before the diagnosis of amyloidosis was established. Protein ASC was also frequently found in hypogammaglobulinemia. Among normal individuals, protein ASC was seldom detected in the serum by our techniques, but there was a noticeable increase with age and during pregnancy. Moreover, a more sensitive technique, immunoelectro-osmophoresis, revealed protein ASC in a higher number of sera from both patients and normal controls. Thus protein ASC was suggested to be a normal serum constituent, usually present only in minor quantities. Under certain conditions, protein ASC increases considerably in serum, and may in such instances act as a precursor for the deposition of amyloid fibrils in the tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205522"} {"pmid": "4205523", "title": "Disturbance of serum viscosity in diabetes mellitus.", "content": "Disturbance of serum viscosity in diabetes mellitus. The serum viscosity of diabetic patients has been found to be increased. The elevation averaged 8% above healthy subjects and 6% above nondiabetic patients. The serum viscosity elevation was greater when diabetic sequelae associated with microangiopathy were present. No relation of serum viscosity to age, sex, obesity, duration of disease, or type of treatment was demonstrated. Serum total protein and glucose levels were found to be correlated with serum viscosity, and increases in their serum concentrations were observed in diabetes. Analysis demonstrated that their elevation did not explain either the viscosity increase or the difference in viscosity between diabetics with and without sequelae.Intrinsic viscosity, abbreviated [eta], is a concentration-independent solute property related to molecular shape. [eta] was found to be 7% higher in diabetic than in normal serum. The [eta] difference accounted for at least half of the serum viscosity elevation. The rest of the increase was due to increased serum protein level and increased nonprotein solids, presumably glucose and lipid. Associated with increased [eta] was a decline in albumin: globulin ratio and elevation of the acute phase reactant proteins, alpha(1)-acid glycoprotein, alpha(1)-antitrypsin, haptoglobin, and ceruloplasmin. Studies comparing diabetic and normal serum fractionated by using 21.5% sodium sulfate showed that changes in [eta] were attributable to changes in serum protein composition rather than an inherent qualitative disturbance of protein present in one of the fractions. Since serum viscosity is elevated in early diabetes, it may be a part of the metabolic disturbance of diabetes and could play a role in the development of diabetic microangiopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205523"} {"pmid": "4205525", "title": "Local and systemic cell-mediated immunity after immunization of guinea pigs with live or killed m. tuberculosis by various routes.", "content": "Local and systemic cell-mediated immunity after immunization of guinea pigs with live or killed m. tuberculosis by various routes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205525"} {"pmid": "4205526", "title": "The isolation and characterization of an anti-sheep red blood cell antibody having limited heterogeneity.", "content": "The isolation and characterization of an anti-sheep red blood cell antibody having limited heterogeneity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205526"} {"pmid": "4205528", "title": "Antigenic studies of J chain.", "content": "Antigenic studies of J chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205528"} {"pmid": "4205527", "title": "Characterization of the Fv fragment isolated from a human immunoglobulin M.", "content": "Characterization of the Fv fragment isolated from a human immunoglobulin M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205527"} {"pmid": "4205529", "title": "Requirement for bone marrow-derived cells in resistance to Listeria.", "content": "Requirement for bone marrow-derived cells in resistance to Listeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205529"} {"pmid": "4205518", "title": "The cooperative health statistics system.", "content": "The cooperative health statistics system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205518"} {"pmid": "4205519", "title": "Survey instrument to study institutional care services for convalescent and long-term patients.", "content": "Survey instrument to study institutional care services for convalescent and long-term patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205519"} {"pmid": "4205530", "title": "Changes in antigenic properties of human C3 upon activation and conversion by trypsin.", "content": "Changes in antigenic properties of human C3 upon activation and conversion by trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205530"} {"pmid": "4205531", "title": "Effect of polyadenine: polyuridine on brucellosis in conventional and congenitally athymic mice.", "content": "Effect of polyadenine: polyuridine on brucellosis in conventional and congenitally athymic mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205531"} {"pmid": "4205532", "title": "Mucosal and glandular distribution of immunoglobulin components: differential localization of free and bound SC in secretory epithelial cells.", "content": "Mucosal and glandular distribution of immunoglobulin components: differential localization of free and bound SC in secretory epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205532"} {"pmid": "4205533", "title": "Immunoglobulins with multiple binding functions. II. The use of nylon-polyserine whisker discs in screening myeloma immunoglobulins for binding activity.", "content": "Immunoglobulins with multiple binding functions. II. The use of nylon-polyserine whisker discs in screening myeloma immunoglobulins for binding activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205533"} {"pmid": "4205524", "title": "Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow.", "content": "Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow. The effects of phenobarbital treatment for 12 days on the regional distribution of blood flow and on the disposition of two model drugs, antipyrine and d-propranolol, have been determined in six unanesthetized rhesus monkeys. Phenobarbital significantly increased total hepatic blood flow from 179+/-15 to 239+/-27 ml/min. Liver weight was increased to a similar degree (34%) in phenobarbital-treated animals as compared to control monkeys. The clearance of both antipyrine and d-propranolol was increased and the half-life decreased significantly by phenobarbital. Analysis of the data by a perfusion-limited pharmacokinetic model showed that the changes in antipyrine clearance were due almost entirely to enzyme induction. On the other hand, with d-propranolol, the increase in liver blood flow contributed as much to the enhanced clearance as did the stimulation of drug metabolism. The mechanism by which phenobarbital produces the frequently observed increase in drug clearance, therefore, depends upon the initial clearance value of the drug. For low clearance drugs like antipyrine, clearance changes occur largely as a result of enzyme induction. With higher clearance drugs, the effects of increased hepatic blood flow become progressively more important the greater the initial clearance value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205524"} {"pmid": "4205534", "title": "Studies of cellular immunity in Chagas disease: effect of glutaraldehyde-treated specific antigen on inhibition of leukocyte migration.", "content": "Studies of cellular immunity in Chagas disease: effect of glutaraldehyde-treated specific antigen on inhibition of leukocyte migration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205534"} {"pmid": "4205536", "title": "Medial occipital projections to the nucleus of Darkschewitsch of rhesus monkey.", "content": "Medial occipital projections to the nucleus of Darkschewitsch of rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205536"} {"pmid": "4205535", "title": "Trouble-free microbiologic serum and red cell folate assays.", "content": "Trouble-free microbiologic serum and red cell folate assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205535"} {"pmid": "4205537", "title": "Lactic dehydrogenase activity in the hair follicles of the stump-tailed macaque (Macaca speciosa).", "content": "Lactic dehydrogenase activity in the hair follicles of the stump-tailed macaque (Macaca speciosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205537"} {"pmid": "4205539", "title": "Carbaryl residues in bees, honey, and bee bread following exposure to carbaryl via the food supply.", "content": "Carbaryl residues in bees, honey, and bee bread following exposure to carbaryl via the food supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205539"} {"pmid": "4205538", "title": "PCB levels in egg yolks associated with embryonic mortality and deformity of hatched chicks.", "content": "PCB levels in egg yolks associated with embryonic mortality and deformity of hatched chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205538"} {"pmid": "4205545", "title": "Spontaneous awake EEG patterns in three lines of primate evolution.", "content": "Spontaneous awake EEG patterns in three lines of primate evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205545"} {"pmid": "4205546", "title": "Interocular transfer of mirror image discriminations by chiasm-sectioned monkeys.", "content": "Interocular transfer of mirror image discriminations by chiasm-sectioned monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205546"} {"pmid": "4205547", "title": "Loss of social group affinity following prefrontal lesions in free-ranging macaques.", "content": "Loss of social group affinity following prefrontal lesions in free-ranging macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205547"} {"pmid": "4205548", "title": "Concerning the influence of experimental conditions on social interactions initiated by telestimulation in squirrel monkey groups.", "content": "Concerning the influence of experimental conditions on social interactions initiated by telestimulation in squirrel monkey groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205548"} {"pmid": "4205549", "title": "Interocular reversal of preference for lateral mirror-image shapes by the monkey with sectioned optic chiasm.", "content": "Interocular reversal of preference for lateral mirror-image shapes by the monkey with sectioned optic chiasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205549"} {"pmid": "4205551", "title": "On the sensitivity of pseudomonas and proteus to the combination of trimethoprim and sulphamethoxazole.", "content": "On the sensitivity of pseudomonas and proteus to the combination of trimethoprim and sulphamethoxazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205551"} {"pmid": "4205550", "title": "Control of catabolism of mitochondria in oncogenesis. I. Increase of hepatic mitochondrial population during feeding inactive or marginally active amino azo dyes: absence of de novo biosynthesis.", "content": "Control of catabolism of mitochondria in oncogenesis. I. Increase of hepatic mitochondrial population during feeding inactive or marginally active amino azo dyes: absence of de novo biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205550"} {"pmid": "4205552", "title": "Follow-up of a group of workers exposed to dusts containing derivatives of Bacillus subtilis.", "content": "Follow-up of a group of workers exposed to dusts containing derivatives of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205552"} {"pmid": "4205553", "title": "Clinical and immunological responses to enzymes of Bacillus subtilis in factory workers and consumers.", "content": "Clinical and immunological responses to enzymes of Bacillus subtilis in factory workers and consumers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205553"} {"pmid": "4205554", "title": "Farmer's lung: a comparison of simple diagnostic techniques and antigen preparation in human and bovine disease.", "content": "Farmer's lung: a comparison of simple diagnostic techniques and antigen preparation in human and bovine disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205554"} {"pmid": "4205555", "title": "The anatomy of the mitochondrial DNA. The localization of the heat-induced and RNAase-induced scissions in the phosphodiester backbones.", "content": "The anatomy of the mitochondrial DNA. The localization of the heat-induced and RNAase-induced scissions in the phosphodiester backbones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205555"} {"pmid": "4205556", "title": "Mutants of Bacillus subtilis blocked in acetoin reductase.", "content": "Mutants of Bacillus subtilis blocked in acetoin reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205556"} {"pmid": "4205558", "title": "Comparison of the suppressive effect of thymus cells and the suppression by neonatal application of antigen.", "content": "Comparison of the suppressive effect of thymus cells and the suppression by neonatal application of antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205558"} {"pmid": "4205557", "title": "Active subunits of transaldolase bound to sepharose.", "content": "Active subunits of transaldolase bound to sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205557"} {"pmid": "4205559", "title": "Antibodies specific for human T lymphocytes in cold agglutinin and lymphocytotoxic sera.", "content": "Antibodies specific for human T lymphocytes in cold agglutinin and lymphocytotoxic sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205559"} {"pmid": "4205560", "title": "Seasonal and hormonally induced changes in the serum level of the precursor protein vitellogenin in relation to ovarian vitellogenic growth in the toad Bufo bufo bufo (L.).", "content": "Seasonal and hormonally induced changes in the serum level of the precursor protein vitellogenin in relation to ovarian vitellogenic growth in the toad Bufo bufo bufo (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205560"} {"pmid": "4205561", "title": "The effect of lesions in the centromedian nucleus of the thalamus on the monkey's performance in delayed alternation and object reversal tasks.", "content": "The effect of lesions in the centromedian nucleus of the thalamus on the monkey's performance in delayed alternation and object reversal tasks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205561"} {"pmid": "4205563", "title": "Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations.", "content": "Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205563"} {"pmid": "4205564", "title": "The effect of an ethanol-extractable thyroxine binding substance in plasma on the measurement of thyroxine by competitive binding.", "content": "The effect of an ethanol-extractable thyroxine binding substance in plasma on the measurement of thyroxine by competitive binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205564"} {"pmid": "4205566", "title": "Late hemispherectomy complications. Unilateral hydrocephalus from aqueductal obstruction.", "content": "Late hemispherectomy complications. Unilateral hydrocephalus from aqueductal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205566"} {"pmid": "4205567", "title": "Participation of medial pontine reticular formation in eye movement generation in monkey.", "content": "Participation of medial pontine reticular formation in eye movement generation in monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205567"} {"pmid": "4205569", "title": "Precentral and postcentral cortical activity in association with visually triggered movement.", "content": "Precentral and postcentral cortical activity in association with visually triggered movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205569"} {"pmid": "4205568", "title": "Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb.", "content": "Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205568"} {"pmid": "4205565", "title": "Progesterone-binding protein in human myometrium. Influence of metal ions on binding.", "content": "Progesterone-binding protein in human myometrium. Influence of metal ions on binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205565"} {"pmid": "4205572", "title": "Scanning of the apical pole of distal tubular cells under differing acid-base conditions.", "content": "Scanning of the apical pole of distal tubular cells under differing acid-base conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205572"} {"pmid": "4205562", "title": "Muscle AMP aminohydrolase. X. Effect of anions on the kinetic and regulatory properties of the rat muscle enzyme.", "content": "Muscle AMP aminohydrolase. X. Effect of anions on the kinetic and regulatory properties of the rat muscle enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205562"} {"pmid": "4205579", "title": "Zen macrobiotic dietary problems in infancy.", "content": "Zen macrobiotic dietary problems in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205579"} {"pmid": "4205580", "title": "Serum aldosterone concentrations related to sodium balance in the newborn infant.", "content": "Serum aldosterone concentrations related to sodium balance in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205580"} {"pmid": "4205578", "title": "Catheter complications in total parenteral nutrition. A prospective study of 200 consecutive patients.", "content": "Catheter complications in total parenteral nutrition. A prospective study of 200 consecutive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205578"} {"pmid": "4205581", "title": "Visceral neurofibromatosis and hypertension in childhood.", "content": "Visceral neurofibromatosis and hypertension in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205581"} {"pmid": "4205582", "title": "Neonatal gonococcal arthritis: three cases and review of the literature.", "content": "Neonatal gonococcal arthritis: three cases and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205582"} {"pmid": "4205583", "title": "Chelation therapy in children with subclinical plumbism.", "content": "Chelation therapy in children with subclinical plumbism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205583"} {"pmid": "4205584", "title": "Acetylcholinesterase from a non-membrane source (Bungarus fasciatus venom).", "content": "Acetylcholinesterase from a non-membrane source (Bungarus fasciatus venom).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205584"} {"pmid": "4205585", "title": "Alcoholism and animals.", "content": "Alcoholism and animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205585"} {"pmid": "4205586", "title": "Smallpox vaccination and its consequences: first experiences with the highly attenuated smallpox vaccine \"MVA\".", "content": "Smallpox vaccination and its consequences: first experiences with the highly attenuated smallpox vaccine \"MVA\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205586"} {"pmid": "4205591", "title": "Calcium-induced extrusion of secretory granules (exocytosis) in mast cells exposed to 48-80 or the ionophores A-23187 and X-537A.", "content": "Calcium-induced extrusion of secretory granules (exocytosis) in mast cells exposed to 48-80 or the ionophores A-23187 and X-537A. Isolated peritoneal mast cells from rats were observed, by phase contrast microscopy, to extrude secretory granules when exposed to 48/80 or the ionophores A-23187 and X-537A, which are known to facilitate transmembrane fluxes of calcium. These effects were abolished when the cells were treated with EDTA and suspended in a Ca-free environment. Ca-deprived cells exposed to any one of the three drugs promptly extruded granules when calcium, but not magnesium, was added to the incubation medium. Such Ca-evoked or Ca-dependent responses persisted when Na was omitted from the incubation medium and replaced with sucrose, choline, or K. The responses thus seem independent of possible shifts in the alkali metal ions. The results are considered support for the view that Ca influx mediates stimulus-secretion coupling and does so by initiating exocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205591"} {"pmid": "4205592", "title": "A comparison of bovine prothrombin, factor IX (Christmas factor), and factor X (Stuart factor).", "content": "A comparison of bovine prothrombin, factor IX (Christmas factor), and factor X (Stuart factor). A comparison has been made of the electrophoretic behavior, chemical composition, amino-terminal sequence, and immunological properties of bovine prothrombin, factor IX (Christmas factor), and factor X (Stuart factor). Some immunological crossreactivity was found between the antibody to prothrombin and factor X although prothrombin and factor X differ substantially in amino-acid and carbohydrate composition. Considerable amino-acid sequence homology was found in the amino-terminal portion of prothrombin, factor IX, and the light chain of factor X. These data provide further evidence to support the hypothesis that at least three of the vitamin K-dependent clotting factors have evolved from a common ancestral gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205592"} {"pmid": "4205593", "title": "In vitro synthesis of ribosomal proteins directed by Escherichia coli DNA.", "content": "In vitro synthesis of ribosomal proteins directed by Escherichia coli DNA. In vitro synthesis of a number of E. coli 30S ribosomal proteins has been demonstrated in a cell-free system consisting of ribosomes, initiation factors, RNA polymerase, a fraction containing soluble enzymes and factors, and E. coli DNA. DNA-dependent synthesis of the following 30S proteins has been demonstrated: S4, S5, S7, S8, S9, S10, S13, S14, S16, S19, and S20.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205593"} {"pmid": "4205594", "title": "Chemotactic activity in dialyzable transfer factor.", "content": "Chemotactic activity in dialyzable transfer factor. Dialyzable transfer factor from human leukocytes was found to be strongly chemotactic for granulocytes and weakly chemotactic for monocytes in vitro. Chemotactic properties were also demonstrated in vivo in rhesus monkey skin. Initial purification of the dialyzable transfer factor by Sephadex G-25 chromatography revealed multiple fractions containing material with 255-nm absorbance. The fractions containing chemotactic activity were also capable of transferring delayed hypersensitivity to rhesus monkeys. This chemotactic material has an apparent molecular weight of 5000 daltons or less and was not inactivated by goat antibody to components C3 or C5 of human complement; chemotactic activity was lost after storage for two weeks at 4 degrees and the activity of two of three preparations was decreased by heating for 30 min at 56 degrees . This previously undescribed chemotactic activity of dialyzable transfer factor may have significance in relation to cell-mediated immune responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205594"} {"pmid": "4205595", "title": "Immunostimulation with bacterial phospholipid extracts.", "content": "Immunostimulation with bacterial phospholipid extracts. Injection of bacterial phospholipid extracts (EBP) into mice increased their resistance towards a Listeria monocytogenes infection. The blood clearance of virulent Salmonella typhimurium was enhanced and the degree of clearance correlated with the dose of extract injected. The multiplication of Listeria monocytogenes in spleen and liver of mice was inhibited and this inhibition was also correlated with the amount of extract injected. The absence of apparent toxicity in mice, of splenoand hepatomegaly, and of lymphoid hyperplasia, distinguish this immunostimulant from other known bacterial stimulants of host resistance to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205595"} {"pmid": "4205596", "title": "Toxigenic algae.", "content": "Toxigenic algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205596"} {"pmid": "4205597", "title": "Role of prostaglandins in estrogen-induced uterine hyperemia.", "content": "Role of prostaglandins in estrogen-induced uterine hyperemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205597"} {"pmid": "4205598", "title": "Inability of prostaglandin synthesis inhibitors to affect adipose tissue lipolysis.", "content": "Inability of prostaglandin synthesis inhibitors to affect adipose tissue lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205598"} {"pmid": "4205599", "title": "Specific binding sites in the rabbit kidney for prostaglandin A.", "content": "Specific binding sites in the rabbit kidney for prostaglandin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205599"} {"pmid": "4205602", "title": "Increased forearm venous compliance during exercise with nitroglycerin.", "content": "Increased forearm venous compliance during exercise with nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205602"} {"pmid": "4205603", "title": "The estimation of molecular weight of tonofilaments by gel-filtration in 6M guanidine hydrochloride and by sodium dodecylsulfate acrylamide gel electrophoresis.", "content": "The estimation of molecular weight of tonofilaments by gel-filtration in 6M guanidine hydrochloride and by sodium dodecylsulfate acrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205603"} {"pmid": "4205604", "title": "Insulin deficiency and hyperosmolar coma.", "content": "Insulin deficiency and hyperosmolar coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205604"} {"pmid": "4205605", "title": "Gonococcal infection. Clinical, epidemiologic and laboratory perspectives.", "content": "Gonococcal infection. Clinical, epidemiologic and laboratory perspectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205605"} {"pmid": "4205606", "title": "Thyrotropin-releasing hormone.", "content": "Thyrotropin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205606"} {"pmid": "4205612", "title": "A contribution to the solitary ciliogenesis.", "content": "A contribution to the solitary ciliogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205612"} {"pmid": "4205611", "title": "Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats.", "content": "Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205611"} {"pmid": "4205613", "title": "Contribution to study of the arterial supply of the gastrointestinal tract of the toad (Bufo bufo).", "content": "Contribution to study of the arterial supply of the gastrointestinal tract of the toad (Bufo bufo).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205613"} {"pmid": "4205618", "title": "Macroglobulin-producing histiocytic lymphoma of hepatic origin.", "content": "Macroglobulin-producing histiocytic lymphoma of hepatic origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205618"} {"pmid": "4205627", "title": "Residues of mirex and certain other chlorinated hydrocarbon insecticides in beef fat--1971.", "content": "Residues of mirex and certain other chlorinated hydrocarbon insecticides in beef fat--1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205627"} {"pmid": "4205629", "title": "Perforated jejunal diverticulum diagnosed as acute appendicitis.", "content": "Perforated jejunal diverticulum diagnosed as acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205629"} {"pmid": "4205630", "title": "Osteochondritis dissecans of the talus.", "content": "Osteochondritis dissecans of the talus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205630"} {"pmid": "4205631", "title": "Neurological sequelae of decompression in supersonic transport aircraft.", "content": "Neurological sequelae of decompression in supersonic transport aircraft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205631"} {"pmid": "4205633", "title": "Specific impairment of host defense for pseudomonas infection in mice by a burn toxin derived from thermally altered human skin.", "content": "Specific impairment of host defense for pseudomonas infection in mice by a burn toxin derived from thermally altered human skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205633"} {"pmid": "4205635", "title": "The unilateral engram.", "content": "The unilateral engram. It is proposed that the corpus callosum has a major role in the processes of memory; first, by providing access by each hemisphere to memory traces stored in the other, and second, by controlling the formation of memory traces in such a way that they are laid down in only one hemisphere instead of in both. This dual mechanism would have the effect of doubling the mnemonic storage capacity of the brain. Evidence in favor of this hypothesis in briefly reviewed. It is also supported by experiments using electrical excitation of the striate cortex as a conditional stimulus in macaques, and by experiments on maze behavior in the m e species. Experiments with the anterior commissure, on the other hand, show that it, in contrast to the splenium of the corpus callosum, can actually transfer an engram from one hemisphere to the other. Finally, it is shown that the splenium provides an effective path of communication between the central visual system in one hemisphere and the amygdala in the other.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205635"} {"pmid": "4205636", "title": "Some characteristics of self-stimulation behavior of dogs.", "content": "Some characteristics of self-stimulation behavior of dogs. Self-stimulation was studied in dogs chronically implanted with electrodes in different points within the basal forebrain. The animals exhibiting pure self-rewarding behavior were defined as \"optimal\" and \"good self-stimulators\", whereas those with concomitant aversive phenomena were incorporated into the third category called \"self-stimulation-withdrawal\". In \"optimal self-stimulators\" a remarkable resistance of the response to extinction was noted. A strong negative attitude toward food was found in four dogs upon stimulation of the self-rewarding loci. Penile erection accompanied self-stimulation in two animals. Sniffing at first always followed incentive brain stimulation, but later it appeared at the beginning of each experiment and/or preceded the bouts of pressing. A rise of hypothalamic temperature was noted in mast of the animals. In some cases this was equal to or exceeded 1 degree Celsius. The temperature increase was accompanied by intense panting between the bouts. Seizures appeared locally as contractions of masticatory muscles and sometimes developed into a generalized fit. Anatomically the \"reward area\" in the dog extends from the septum and the preoptic area to the mammillary bodies and reaches laterally to the internal capsule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205636"} {"pmid": "4205637", "title": "Analysis of the polychlorinated biphenyl problem. Application of gas chromatography-mass spectrometry with computer controlled repetitive data acquisition from selected specific lons.", "content": "Analysis of the polychlorinated biphenyl problem. Application of gas chromatography-mass spectrometry with computer controlled repetitive data acquisition from selected specific lons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205637"} {"pmid": "4205639", "title": "Demonstration of nuclear and cytoplasmic fluorescence in brain tissues of schizophrenic and nonschizophrenic patients.", "content": "Demonstration of nuclear and cytoplasmic fluorescence in brain tissues of schizophrenic and nonschizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205639"} {"pmid": "4205641", "title": "Health services for foster children: an evaluation of agency programs.", "content": "Health services for foster children: an evaluation of agency programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205641"} {"pmid": "4205644", "title": "Clinical and social aspects of a non-geriatric long-stay psychiatric unit.", "content": "Clinical and social aspects of a non-geriatric long-stay psychiatric unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205644"} {"pmid": "4205643", "title": "Antidepressant effect of thyrotropin-releasing hormone (TRH) and the plasma thyrotropin levels in depression.", "content": "Antidepressant effect of thyrotropin-releasing hormone (TRH) and the plasma thyrotropin levels in depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205643"} {"pmid": "4205642", "title": "L-glutamate decarboxylase and choline acetyltransferase activity in the substantia nigra and the striatum after surgical interruption of the strio-nigral fibres of the baboon.", "content": "L-glutamate decarboxylase and choline acetyltransferase activity in the substantia nigra and the striatum after surgical interruption of the strio-nigral fibres of the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205642"} {"pmid": "4205645", "title": "Timing of meiotic crossing-over in Drosophila melanogaster.", "content": "Timing of meiotic crossing-over in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205645"} {"pmid": "4205646", "title": "Effects of cadmium on development time and prepupal puffing pattern of Drosophila melanogaster.", "content": "Effects of cadmium on development time and prepupal puffing pattern of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205646"} {"pmid": "4205647", "title": "A chlorine-free embedding medium for use in x-ray analytical electron microscope localisation of chloride in biological tissues.", "content": "A chlorine-free embedding medium for use in x-ray analytical electron microscope localisation of chloride in biological tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205647"} {"pmid": "4205640", "title": "Gonococcal vaccine studies in Inuvik.", "content": "Gonococcal vaccine studies in Inuvik.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205640"} {"pmid": "4205650", "title": "Maridomycin, a new macrolide antibiotic. I. Taxonomy and fermentation.", "content": "Maridomycin, a new macrolide antibiotic. I. Taxonomy and fermentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205650"} {"pmid": "4205649", "title": "Functional radioisotope investigations in chronic nephritis.", "content": "Functional radioisotope investigations in chronic nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205649"} {"pmid": "4205648", "title": "The effects of different preparative procedures on the ultrastructure of the hamster ovary. I. Effects of various fixative solutions on ovarian oocytes and their granulosa cells.", "content": "The effects of different preparative procedures on the ultrastructure of the hamster ovary. I. Effects of various fixative solutions on ovarian oocytes and their granulosa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205648"} {"pmid": "4205652", "title": "Aminoglycoside antibiotics. IV. BU-1709 E1 and E2, new aminoglycoside antibiotics related to the butirosins.", "content": "Aminoglycoside antibiotics. IV. BU-1709 E1 and E2, new aminoglycoside antibiotics related to the butirosins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205652"} {"pmid": "4205651", "title": "Study on in vitro activity of the antibiotics tobramycin and gentamicin against Pseudomonas aeruginosa clinical strains.", "content": "Study on in vitro activity of the antibiotics tobramycin and gentamicin against Pseudomonas aeruginosa clinical strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205651"} {"pmid": "4205653", "title": "Isolation and characterization of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid from Pseudomonas aeruginosa grown on n-paraffin.", "content": "Isolation and characterization of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid from Pseudomonas aeruginosa grown on n-paraffin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205653"} {"pmid": "4205654", "title": "Bias functions and operating characteristics of rats discriminating auditory stimuli.", "content": "Bias functions and operating characteristics of rats discriminating auditory stimuli. Rats were trained to discriminate between two bursts of random noise that differed in intensity. In a two-lever, discrete-trial procedure, correct responses were reinforced with brain stimulation, and incorrect responses produced timeout. Responding was studied as a function of the decibel difference between the stimuli, the probabilities of presenting the stimuli, the relative duration of timeout consequent upon the two types of incorrect responses, and the absolute duration of timeout consequent upon incorrect responses. The results showed that the distribution of responses between the two levers depended upon the stimulus probabilities, but were independent of either the absolute or relative durations of timeout. When the stimulus probabilities were varied, the response probabilities did not match the stimulus probabilities; when the relative durations of timeout were varied, the animals did not obtain the maximum rate of reinforcement per unit time. Instead, the animals distributed their responses so as to obtain the maximum number of reinforcements at each level of discrimination. In addition, the level of discrimination increased as a function of the decibel difference between the stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205654"} {"pmid": "4205658", "title": "Monkeys agree-noise is upsetting.", "content": "Monkeys agree-noise is upsetting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205658"} {"pmid": "4205657", "title": "Basic studies on 3', 4'-dideoxykanamycin B.", "content": "Basic studies on 3', 4'-dideoxykanamycin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205657"} {"pmid": "4205659", "title": "Role of a myocardial depressant factor in shock states.", "content": "Role of a myocardial depressant factor in shock states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205659"} {"pmid": "4205662", "title": "Thermal degradation of some parenteral solutions of reserpine. 2. Effects of ionic strength, dielectric constant, inert gas and stabilizers.", "content": "Thermal degradation of some parenteral solutions of reserpine. 2. Effects of ionic strength, dielectric constant, inert gas and stabilizers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205662"} {"pmid": "4205660", "title": "The case history of monkey no. 109: first experimentally produced vertical gaze palsy.", "content": "The case history of monkey no. 109: first experimentally produced vertical gaze palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205660"} {"pmid": "4205661", "title": "Potential changes associated with eye movements in the thalamus, visual cortex and reticular formation.", "content": "Potential changes associated with eye movements in the thalamus, visual cortex and reticular formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205661"} {"pmid": "4205686", "title": "Birth order and parental experience in monkeys and man.", "content": "Birth order and parental experience in monkeys and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205686"} {"pmid": "4205687", "title": "Biochemistry of natural proteinase inhibitors.", "content": "Biochemistry of natural proteinase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205687"} {"pmid": "4205688", "title": "Biological control of mosquito larvae.", "content": "Biological control of mosquito larvae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205688"} {"pmid": "4205689", "title": "Courtship behavior in Drosophila.", "content": "Courtship behavior in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205689"} {"pmid": "4205690", "title": "Animal learning. Visceral and autonomic conditioning.", "content": "Animal learning. Visceral and autonomic conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205690"} {"pmid": "4205691", "title": "Spatial vision.", "content": "Spatial vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205691"} {"pmid": "4205692", "title": "Somesthesis.", "content": "Somesthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205692"} {"pmid": "4205693", "title": "Brain function: changing ideas on the role of sensory, motor, and association cortex in behavior.", "content": "Brain function: changing ideas on the role of sensory, motor, and association cortex in behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205693"} {"pmid": "4205695", "title": "Coccidioidomycosis in a baboon recently imported from California.", "content": "Coccidioidomycosis in a baboon recently imported from California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205695"} {"pmid": "4205699", "title": "Intracellular location of newly synthesized growth hormone.", "content": "Intracellular location of newly synthesized growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205699"} {"pmid": "4205700", "title": "On the macromolecular composition of the jelly coat from Strongylocentrotus purpuratus eggs.", "content": "On the macromolecular composition of the jelly coat from Strongylocentrotus purpuratus eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205700"} {"pmid": "4205701", "title": "Macrophage spreading in vitro. II. Manganese and other metals as inducers or as co-factors for induced spreading.", "content": "Macrophage spreading in vitro. II. Manganese and other metals as inducers or as co-factors for induced spreading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205701"} {"pmid": "4205702", "title": "A radioimmunoassay for myosin in cultured skeletal muscle cells.", "content": "A radioimmunoassay for myosin in cultured skeletal muscle cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205702"} {"pmid": "4205711", "title": "Effect of beta-mercaptoethanol on the binary fission in Spirotomum ambiguum Mull-Ehrbg.", "content": "Effect of beta-mercaptoethanol on the binary fission in Spirotomum ambiguum Mull-Ehrbg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205711"} {"pmid": "4205712", "title": "The role of wounds in the epidemiology of nosocomial infections due to Pseudomonas aeruginosa.", "content": "The role of wounds in the epidemiology of nosocomial infections due to Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205712"} {"pmid": "4205717", "title": "Gene control of soluble protein levels during development of abnormal abdomen in Drosophila.", "content": "Gene control of soluble protein levels during development of abnormal abdomen in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205717"} {"pmid": "4205718", "title": "Editorial: Trimethoprim-sulfamethoxazole (TMP-SMZ)--better late than never.", "content": "Editorial: Trimethoprim-sulfamethoxazole (TMP-SMZ)--better late than never.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205718"} {"pmid": "4205721", "title": "A study on the effects of ibuprofen on the metabolism of antipyrine in man.", "content": "A study on the effects of ibuprofen on the metabolism of antipyrine in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205721"} {"pmid": "4205723", "title": "Letter: Intal in refractory asthmatic paediatric cases.", "content": "Letter: Intal in refractory asthmatic paediatric cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205723"} {"pmid": "4205722", "title": "Cannabis and reverse tolerance: pharmacological entity or psychological phenomenon?", "content": "Cannabis and reverse tolerance: pharmacological entity or psychological phenomenon?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205722"} {"pmid": "4205713", "title": "Comparable bactericidal activity of two chemosterilizers.", "content": "Comparable bactericidal activity of two chemosterilizers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205713"} {"pmid": "4205715", "title": "Effect of microbial interactions on in vitro plaque formation by Streptococcus mutans.", "content": "Effect of microbial interactions on in vitro plaque formation by Streptococcus mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205715"} {"pmid": "4205714", "title": "Radiographic cephalometric method of assessment of craniofacial growth in monkeys.", "content": "Radiographic cephalometric method of assessment of craniofacial growth in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205714"} {"pmid": "4205716", "title": "Electron probe microanalysis of human enamel microstructure.", "content": "Electron probe microanalysis of human enamel microstructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205716"} {"pmid": "4205731", "title": "An evaluation of EDTA in endodontics.", "content": "An evaluation of EDTA in endodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205731"} {"pmid": "4205733", "title": "Medicolegal blood grouping tests (parentage exclusion tests).", "content": "Medicolegal blood grouping tests (parentage exclusion tests).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205733"} {"pmid": "4205734", "title": "Clinical microbiology of unusual Pseudomonas species.", "content": "Clinical microbiology of unusual Pseudomonas species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205734"} {"pmid": "4205738", "title": "Immunodiffusion studies on some Proteus strains.", "content": "Immunodiffusion studies on some Proteus strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205738"} {"pmid": "4205739", "title": "The significance of Australia-antibody in blood donors. Study of liver histology in donors and post-transfusion hepatitis in recipients.", "content": "The significance of Australia-antibody in blood donors. Study of liver histology in donors and post-transfusion hepatitis in recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205739"} {"pmid": "4205740", "title": "New electrophoretic information on the surface composition of the rat erythrocyte.", "content": "New electrophoretic information on the surface composition of the rat erythrocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205740"} {"pmid": "4205741", "title": "Bacillus megaterium, KM beta-galactosidase: purification by affinity chromatography and characterization of the active species.", "content": "Bacillus megaterium, KM beta-galactosidase: purification by affinity chromatography and characterization of the active species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205741"} {"pmid": "4205742", "title": "Bacteriophage-coded thymidylate synthetase. Evidence that the T4 enzyme is a capsid protein.", "content": "Bacteriophage-coded thymidylate synthetase. Evidence that the T4 enzyme is a capsid protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205742"} {"pmid": "4205743", "title": "Alpha-L-iduronidase activity in cultured skin fibroblasts and amniotic fluid cells.", "content": "Alpha-L-iduronidase activity in cultured skin fibroblasts and amniotic fluid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205743"} {"pmid": "4205748", "title": "Computational methods in beam therapy planning.", "content": "Computational methods in beam therapy planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205748"} {"pmid": "4205749", "title": "EXTDOS 71. Revised and expanded version of EXTDOS, a program for treatment planning in external beam therapy.", "content": "EXTDOS 71. Revised and expanded version of EXTDOS, a program for treatment planning in external beam therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205749"} {"pmid": "4205750", "title": "A versatile system for three-dimensional radiation dose computation and display, RTP.", "content": "A versatile system for three-dimensional radiation dose computation and display, RTP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205750"} {"pmid": "4205751", "title": "Program IRREG-calculation of dose from irregularly shaped radiation beams.", "content": "Program IRREG-calculation of dose from irregularly shaped radiation beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205751"} {"pmid": "4205753", "title": "A computer program for optimised stationary beam treatment planning using score functions.", "content": "A computer program for optimised stationary beam treatment planning using score functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205753"} {"pmid": "4205752", "title": "National Cancer Center radiotherapy computer system.", "content": "National Cancer Center radiotherapy computer system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205752"} {"pmid": "4205755", "title": "Relative performance of selected toxigenic and non-toxigenic isolates of Aspergillus flavus Link ex Fries on different culture media.", "content": "Relative performance of selected toxigenic and non-toxigenic isolates of Aspergillus flavus Link ex Fries on different culture media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205755"} {"pmid": "4205756", "title": "Uterine bleeding in rhesus monkeys after insertion of polyethylene and copper containing polyethylene intrauterine contraceptive devices.", "content": "Uterine bleeding in rhesus monkeys after insertion of polyethylene and copper containing polyethylene intrauterine contraceptive devices. The effect of polyethylene devices, with or without copper, on the incidence of postinsertion bleeding episodes in rhesus monkeys is reported. 24 rhesus monkeys were divided into 4 groups. Group 1 was fitted with the Lippes loop (No. 25). Group 2 was fitted with the loop with 2 cm copper wire (.2 mm diam.) wound around it. Group 3 was fitted with plain polyethylene T-device without copper, and Group 4 was fitted with copper-T (model TCu-200 L). Vaginal smears of all of the monkeys were examined every 12 hours for microscopic bleeding. 1 of the animals of each group showing frank uterine bleeding was sacrificed. The uterus was dissected out and processed for histological studies. The results showed that the incidence of postinsertion bleeding in rhesus monkeys varied according to the design and material of the devices. The severity of bleeding was markedly less with either the plain T-device or the T-device with copper, as compared to Lippes loop with or without this metal. The copper containing Lippes loop caused less bleeding in so far as duration and flow were concerned than the loop without copper. The severity of bleeding in animals fitted with plain T-device was less than that seen after insertion of the plain Lippes loop. This suggests that the design of the device is a crucial factor in bleeding. A comparison between plain T-devices and copper T-devices showed a beneficial action of copper in reducing the incidence of postinsertion bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205756"} {"pmid": "4205757", "title": "Antigenic relationship between ruminant serum proteins.", "content": "Antigenic relationship between ruminant serum proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205757"} {"pmid": "4205758", "title": "Studies on antiviral property of fruiting Myxobacteria (Myxococcus virescens).", "content": "Studies on antiviral property of fruiting Myxobacteria (Myxococcus virescens).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205758"} {"pmid": "4205759", "title": "The primary structures of alpha and beta chains of adult hemoglobin of the Japanese monkey (Macata fuscata fuscata). Biochemical studies on hemoglobins and myoglobins. XI.", "content": "The primary structures of alpha and beta chains of adult hemoglobin of the Japanese monkey (Macata fuscata fuscata). Biochemical studies on hemoglobins and myoglobins. XI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205759"} {"pmid": "4205760", "title": "The primary structures of the alpha and beta polypeptide chains of adult hemoglobin of the Hanumam langur (Presbytis entellus).", "content": "The primary structures of the alpha and beta polypeptide chains of adult hemoglobin of the Hanumam langur (Presbytis entellus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205760"} {"pmid": "4205761", "title": "Chemical modification of neutral subtilopeptidase by aromatic diazo compounds.", "content": "Chemical modification of neutral subtilopeptidase by aromatic diazo compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205761"} {"pmid": "4205762", "title": "Letter: Pure-tone thresholds of the squirrel monkey (Saimiri sciureus).", "content": "Letter: Pure-tone thresholds of the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205762"} {"pmid": "4205763", "title": "Isolation and properties of mutants of the FP2 sex factor of Pseudomonas aeruginosa.", "content": "Isolation and properties of mutants of the FP2 sex factor of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205763"} {"pmid": "4205754", "title": "Gram-negative infections in the ICU.", "content": "Gram-negative infections in the ICU.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205754"} {"pmid": "4205764", "title": "Studies related to penicillins. XI. Mechanism of degradation of benzylpenicillinic and phenoxymethylpenicillinic acid by mercury(II) acetate.", "content": "Studies related to penicillins. XI. Mechanism of degradation of benzylpenicillinic and phenoxymethylpenicillinic acid by mercury(II) acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205764"} {"pmid": "4205765", "title": "The genetic analysis of the direct and correlated response to selection for chaetae in Drosophila melanogaster.", "content": "The genetic analysis of the direct and correlated response to selection for chaetae in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205765"} {"pmid": "4205766", "title": "Genetic and environmental control of a continuous trait, abnormal abdomen, in Drosophila melanogaster.", "content": "Genetic and environmental control of a continuous trait, abnormal abdomen, in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205766"} {"pmid": "4205767", "title": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations.", "content": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205767"} {"pmid": "4205768", "title": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations.", "content": "Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205768"} {"pmid": "4205770", "title": "Acute urethritis in male college students.", "content": "Acute urethritis in male college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205770"} {"pmid": "4205771", "title": "The effect of peroxidized arachidonic acid upon human platelet aggregation.", "content": "The effect of peroxidized arachidonic acid upon human platelet aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205771"} {"pmid": "4205775", "title": "No one told me to.", "content": "No one told me to.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205775"} {"pmid": "4205774", "title": "Evocation of a biphasic febrile response in the rhesus monkey by intracerebral injection of bacterial endotoxins.", "content": "Evocation of a biphasic febrile response in the rhesus monkey by intracerebral injection of bacterial endotoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205774"} {"pmid": "4205769", "title": "Isozyme mutation rate in mutator stock of Drosophila melanogaster.", "content": "Isozyme mutation rate in mutator stock of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205769"} {"pmid": "4205782", "title": "Intestinal microbial flora and proteolytic activity of intestinal contents.", "content": "Intestinal microbial flora and proteolytic activity of intestinal contents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205782"} {"pmid": "4205789", "title": "Amniotic fluid, epinephrine, and norepinephrine. I. Comparison between the human and baboon.", "content": "Amniotic fluid, epinephrine, and norepinephrine. I. Comparison between the human and baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205789"} {"pmid": "4205793", "title": "Gonococcal conjunctivitis.", "content": "Gonococcal conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205793"} {"pmid": "4205794", "title": "Insulin response in patients receiving concentrated infusions of glucose and casein hydrolysate for complete parenteral nutrition.", "content": "Insulin response in patients receiving concentrated infusions of glucose and casein hydrolysate for complete parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205794"} {"pmid": "4205795", "title": "The effects of short-term steroid therapy on lung bacterial clearance and survival in rats.", "content": "The effects of short-term steroid therapy on lung bacterial clearance and survival in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205795"} {"pmid": "4205796", "title": "Total intravenous feeding of infants and children without use of a central venous catheter.", "content": "Total intravenous feeding of infants and children without use of a central venous catheter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205796"} {"pmid": "4205797", "title": "New techniques for long-term intravenous feeding: an artificial gut in 75 patients.", "content": "New techniques for long-term intravenous feeding: an artificial gut in 75 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205797"} {"pmid": "4205790", "title": "Letter: Intrapartum sedation of fetus.", "content": "Letter: Intrapartum sedation of fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205790"} {"pmid": "4205798", "title": "Studies on the growth of Thiobacillus ferrooxidans. II. Toxicity of uranium to growing cultures and tolerance conferred by mutation, other metal cations and EDTA.", "content": "Studies on the growth of Thiobacillus ferrooxidans. II. Toxicity of uranium to growing cultures and tolerance conferred by mutation, other metal cations and EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205798"} {"pmid": "4205800", "title": "Dihydrogenated alkaloids of ergot in geriatric patients: symptomatic treatment of cerebrovascular insufficiency.", "content": "Dihydrogenated alkaloids of ergot in geriatric patients: symptomatic treatment of cerebrovascular insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205800"} {"pmid": "4205799", "title": "Proceedings: Intravenous hyperalimentation in the treatment of inflammatory diseases of the bowel.", "content": "Proceedings: Intravenous hyperalimentation in the treatment of inflammatory diseases of the bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205799"} {"pmid": "4205791", "title": "Letter: Intrapartum sedation of fetus.", "content": "Letter: Intrapartum sedation of fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205791"} {"pmid": "4205803", "title": "X-ray analysis of retinal photoreceptor structure.", "content": "X-ray analysis of retinal photoreceptor structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205803"} {"pmid": "4205804", "title": "An analysis of the absorption and circular dichroism of some visual pigments.", "content": "An analysis of the absorption and circular dichroism of some visual pigments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205804"} {"pmid": "4205792", "title": "Ketamine and epilepsy.", "content": "Ketamine and epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205792"} {"pmid": "4205805", "title": "Serum immunoglobulin levels in women using intrauterine contraceptive devices.", "content": "Serum immunoglobulin levels in women using intrauterine contraceptive devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205805"} {"pmid": "4205806", "title": "Letter: Differentiation of coccidia in cats and transmission of toxoplasmosis.", "content": "Letter: Differentiation of coccidia in cats and transmission of toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205806"} {"pmid": "4205808", "title": "Modulation of hypothalamic ICSS by concurrent limbic stimulation.", "content": "Modulation of hypothalamic ICSS by concurrent limbic stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205808"} {"pmid": "4205809", "title": "Congenital anterior urethral diverticulum in the male.", "content": "Congenital anterior urethral diverticulum in the male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205809"} {"pmid": "4205810", "title": "Geometric penumbra calculations for a gas target neutron source.", "content": "Geometric penumbra calculations for a gas target neutron source.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205810"} {"pmid": "4205811", "title": "X radiation and sensitized lymphocyte migration.", "content": "X radiation and sensitized lymphocyte migration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205811"} {"pmid": "4205812", "title": "Combined cytolytic effect of x irradiation and cell-mediated immune reactions on tumor cells in vitro.", "content": "Combined cytolytic effect of x irradiation and cell-mediated immune reactions on tumor cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205812"} {"pmid": "4205815", "title": "Carcinoembryonic antigen in patients with squamous cell carcinoma of the cervix uteri and vulva.", "content": "Carcinoembryonic antigen in patients with squamous cell carcinoma of the cervix uteri and vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205815"} {"pmid": "4205817", "title": "Control of the differentiated state in somatic cell hybrids.", "content": "Control of the differentiated state in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205817"} {"pmid": "4205816", "title": "Mapping of behavior in Drosophila mosaics.", "content": "Mapping of behavior in Drosophila mosaics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205816"} {"pmid": "4205818", "title": "Genetics of sperm development in Drosophila.", "content": "Genetics of sperm development in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205818"} {"pmid": "4205822", "title": "Determination of regional myocardial blood flow (MBF) in patients with anginal pain.", "content": "Determination of regional myocardial blood flow (MBF) in patients with anginal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205822"} {"pmid": "4205824", "title": "Cobalt 60 treatment field verification by xeroradiography.", "content": "Cobalt 60 treatment field verification by xeroradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205824"} {"pmid": "4205823", "title": "Serial scintigrams in the course of ectopic bone formation in paraplegic patients.", "content": "Serial scintigrams in the course of ectopic bone formation in paraplegic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205823"} {"pmid": "4205813", "title": "Oxygen cycles and metabolic autoregulation.", "content": "Oxygen cycles and metabolic autoregulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205813"} {"pmid": "4205825", "title": "Percentage depth dose for high energy x-ray beams in radiotherapy.", "content": "Percentage depth dose for high energy x-ray beams in radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205825"} {"pmid": "4205814", "title": "The effect of graded hypocapnia and hypercapnia on regional cerebral blood flow and cerebral vessel caliber in the rhesus monkey: study of cerebral hemodynamics following subarachnoid hemorrhage and traumatic internal carotid spasm.", "content": "The effect of graded hypocapnia and hypercapnia on regional cerebral blood flow and cerebral vessel caliber in the rhesus monkey: study of cerebral hemodynamics following subarachnoid hemorrhage and traumatic internal carotid spasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205814"} {"pmid": "4205831", "title": "Reduced sulphation factor in undernourished children.", "content": "Reduced sulphation factor in undernourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205831"} {"pmid": "4205832", "title": "Serum C3 levels in acute glomerulonephritis and postnephritic children.", "content": "Serum C3 levels in acute glomerulonephritis and postnephritic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205832"} {"pmid": "4205833", "title": "Massive gastrointestinal bleeding. A panel by correspondence.", "content": "Massive gastrointestinal bleeding. A panel by correspondence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205833"} {"pmid": "4205834", "title": "Adrenal steroids in the treatment of malignant hematologic disease.", "content": "Adrenal steroids in the treatment of malignant hematologic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205834"} {"pmid": "4205835", "title": "Human prolactin in clinical endocrinology: the impact of radioimmunoassays.", "content": "Human prolactin in clinical endocrinology: the impact of radioimmunoassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205835"} {"pmid": "4205836", "title": "Megavoltage radiation therapy for supraglottic carcinoma. Results of treatment.", "content": "Megavoltage radiation therapy for supraglottic carcinoma. Results of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205836"} {"pmid": "4205837", "title": "Radiation dosimetry for large, irregularly-shaped fields in the treatment of acute lymphocytic leukemia.", "content": "Radiation dosimetry for large, irregularly-shaped fields in the treatment of acute lymphocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205837"} {"pmid": "4205838", "title": "Effect of various atomic number absorbers on skin dose for 10-MeV x rays.", "content": "Effect of various atomic number absorbers on skin dose for 10-MeV x rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205838"} {"pmid": "4205839", "title": "Pseudomonas osteomyelitis. Radiologic features.", "content": "Pseudomonas osteomyelitis. Radiologic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205839"} {"pmid": "4205841", "title": "Chronic overdrive pacing in the control of refractory ventricular arrhythmias.", "content": "Chronic overdrive pacing in the control of refractory ventricular arrhythmias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205841"} {"pmid": "4205842", "title": "Letter: Bacillus cereus endocarditis in an addict.", "content": "Letter: Bacillus cereus endocarditis in an addict.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205842"} {"pmid": "4205844", "title": "Phase IV final health regulations. Commentary and background material as provided by the Cost of Living Council.", "content": "Phase IV final health regulations. Commentary and background material as provided by the Cost of Living Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205844"} {"pmid": "4205845", "title": "Fluorescent antibody studies in malignant melanoma.", "content": "Fluorescent antibody studies in malignant melanoma. Sera from 57 patients with malignant melanoma and 39 control patients were tested by immunofluorescence techniques against 6 melanoma cell lines. Thirty-two per cent of tests with sera from melanoma patients showed fluorescence with these cell lines whereas only 17% of tests with control sera were positive. Reactions occurred in 21% of tests with sera from patients with primary melanoma compared with 40% with secondary melanomata and 54% with \"cured\" melanomata. The cell lines varied in antigenicity but this did not correlate with either pigmentation or length of time in culture. The cell lines which were most reactive with sera from melanoma patients were also most reactive with control sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205845"} {"pmid": "4205846", "title": "Chronic prostatitis--an Australian view.", "content": "Chronic prostatitis--an Australian view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205846"} {"pmid": "4205847", "title": "Studies on carcinogenic azo dyes. 3. Retention of tritium during enzymatic hydroxylation of 3'-methyl-4-dimethylaminoazobenzene(4'-3H or 5'-3H) or chemical substitutions of the related compound, and the effect of the repeated administration of this azo dye on the retention of tritium.", "content": "Studies on carcinogenic azo dyes. 3. Retention of tritium during enzymatic hydroxylation of 3'-methyl-4-dimethylaminoazobenzene(4'-3H or 5'-3H) or chemical substitutions of the related compound, and the effect of the repeated administration of this azo dye on the retention of tritium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205847"} {"pmid": "4205871", "title": "Ocular hypertensive response to alkali burns in the monkey.", "content": "Ocular hypertensive response to alkali burns in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205871"} {"pmid": "4205874", "title": "An apparatus for the measurement of lipoxygenase activity and pentane production.", "content": "An apparatus for the measurement of lipoxygenase activity and pentane production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205874"} {"pmid": "4205876", "title": "Letter: The probable identity of bacilysin and tetaine.", "content": "Letter: The probable identity of bacilysin and tetaine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205876"} {"pmid": "4205873", "title": "The use of blood.", "content": "The use of blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205873"} {"pmid": "4205875", "title": "Studies on the antitumor activity of an alazopeptin isolated from a new strain of Streptomyces.", "content": "Studies on the antitumor activity of an alazopeptin isolated from a new strain of Streptomyces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205875"} {"pmid": "4205877", "title": "Letter: Fusaric acid derivatives: the effect on dopamine beta-hydroxylase.", "content": "Letter: Fusaric acid derivatives: the effect on dopamine beta-hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205877"} {"pmid": "4205878", "title": "The effect of sea star coelomocyte extract on cell-mediated resistance to Listeria monocytogenes in mice.", "content": "The effect of sea star coelomocyte extract on cell-mediated resistance to Listeria monocytogenes in mice. Mice treated with sea star factor (SSF), a protein extracted from sea star coelomocytes, became highly susceptible to infection with a normally sublethal dose of Listeria monocytogenes. This was in contrast to the expected result of increased resistance originally postulated because of the macrophage-activating properties of SSF. Enhanced susceptibility was seen when SSF was given from 96 h before to 48 h after infection with Listeria. Mice pretreated with SSF failed to develop immunity to Listeria when given a dose of organisms capable of immunizing nontreated mice. Treatment of immune mice with SSF did not alter their immune status. In addition, incubation of immune lymphocytes with SSF in vitro did not alter their ability to adoptively transfer immunity to normal recipients. Immune lymphocytes treated with SSF and then incubated with anti-SSF and C did, however, lose the ability to transfer immunity. These results suggest that SSF enhances infection by binding to T lymphocytes, inhibiting their replication upon contact with Listeria antigen and thus preventing the generation of a population of sensitized lymphocytes capable of effecting anti-Listeria immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205878"} {"pmid": "4205879", "title": "Synergism between ecologic and immunologic control mechanisms of intestinal flora.", "content": "Synergism between ecologic and immunologic control mechanisms of intestinal flora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205879"} {"pmid": "4205880", "title": "Resistance of Neisseria gonorrhoeae to phagocytosis: relationship to colonial morphology and surface pili.", "content": "Resistance of Neisseria gonorrhoeae to phagocytosis: relationship to colonial morphology and surface pili.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205880"} {"pmid": "4205882", "title": "New drugs--no. 14. Glibenclamide. Mechanism of action.", "content": "New drugs--no. 14. Glibenclamide. Mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205882"} {"pmid": "4205881", "title": "Pyelonephritis. XVII. Comparison of combinations of vancomycin, ampicillin, streptomycin, and gentamicin in the treatment of enterococcal infection in rats.", "content": "Pyelonephritis. XVII. Comparison of combinations of vancomycin, ampicillin, streptomycin, and gentamicin in the treatment of enterococcal infection in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205881"} {"pmid": "4205884", "title": "The value of radiotherapy in the management of malignant melanoma of the nasal cavity.", "content": "The value of radiotherapy in the management of malignant melanoma of the nasal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205884"} {"pmid": "4205883", "title": "Auto-immunity in nasal allergy.", "content": "Auto-immunity in nasal allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205883"} {"pmid": "4205885", "title": "Gonococcal ophthalmia neonatorum. Relationship of time of infection to relevant control measures.", "content": "Gonococcal ophthalmia neonatorum. Relationship of time of infection to relevant control measures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205885"} {"pmid": "4205886", "title": "Total parenteral nutrition and Crohn's disease.", "content": "Total parenteral nutrition and Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205886"} {"pmid": "4205887", "title": "Mechanisms of carbohydrate-induced hypertriglyceridemia.", "content": "Mechanisms of carbohydrate-induced hypertriglyceridemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205887"} {"pmid": "4205888", "title": "Tuberculosis in Acukland.", "content": "Tuberculosis in Acukland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205888"} {"pmid": "4205889", "title": "Intensive monitoring for adverse drug effects in patients discharged from acute medical wards.", "content": "Intensive monitoring for adverse drug effects in patients discharged from acute medical wards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205889"} {"pmid": "4205892", "title": "Cytological investigation of crossovers induced by irradiation in males of Drosophila melanogaster.", "content": "Cytological investigation of crossovers induced by irradiation in males of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205892"} {"pmid": "4205891", "title": "Study of the mutation process induced by N-nitrosomethylurea at various stages of spermatogenesis of Drosophila melanogaster. Fertility, crossing-over, and recessive sex-linked lethal mutations.", "content": "Study of the mutation process induced by N-nitrosomethylurea at various stages of spermatogenesis of Drosophila melanogaster. Fertility, crossing-over, and recessive sex-linked lethal mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205891"} {"pmid": "4205893", "title": "Investigation of the mutagenic activity of phenothiazines and other drug preparations.", "content": "Investigation of the mutagenic activity of phenothiazines and other drug preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205893"} {"pmid": "4205894", "title": "New boron-induced puffs and modificational localization of a gene.", "content": "New boron-induced puffs and modificational localization of a gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205894"} {"pmid": "4205895", "title": "Study of the competitive capacity of Drosophila melanogaster individuals heterozygous for radioinduced mutations.", "content": "Study of the competitive capacity of Drosophila melanogaster individuals heterozygous for radioinduced mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205895"} {"pmid": "4205898", "title": "Hemochromatosis presenting as diabetic ketoacidosis with extreme hyperglycemia.", "content": "Hemochromatosis presenting as diabetic ketoacidosis with extreme hyperglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205898"} {"pmid": "4205899", "title": "Studies on tetrapeptides related to thyrotropin releasing hormone and luteinizing hormone releasing hormone.", "content": "Studies on tetrapeptides related to thyrotropin releasing hormone and luteinizing hormone releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205899"} {"pmid": "4205900", "title": "The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes.", "content": "The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205900"} {"pmid": "4205901", "title": "Status and prospects of research in hereditary deafness.", "content": "Status and prospects of research in hereditary deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205901"} {"pmid": "4205902", "title": "Longitudinal differentiation of chromosomes.", "content": "Longitudinal differentiation of chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205902"} {"pmid": "4205903", "title": "Localization of gene function.", "content": "Localization of gene function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205903"} {"pmid": "4205904", "title": "Dosage compensation in Drosophila.", "content": "Dosage compensation in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205904"} {"pmid": "4205905", "title": "Recombination deficient mutants of E. coli and other bacteria.", "content": "Recombination deficient mutants of E. coli and other bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205905"} {"pmid": "4205906", "title": "[Studies on the present state of resistance to framycetin among strains of staphylococci, enterobacteriaceae and pseudomonas].", "content": "[Studies on the present state of resistance to framycetin among strains of staphylococci, enterobacteriaceae and pseudomonas].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205906"} {"pmid": "4205907", "title": "Levodopa in the treatment of arterial insufficiency of the lower limbs. Clinical and rheographic trial.", "content": "Levodopa in the treatment of arterial insufficiency of the lower limbs. Clinical and rheographic trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205907"} {"pmid": "4205908", "title": "Unprimed glucan biosynthesis by a particulate ADP-glucose-glucan glucosyl transferase from an Escherichia coli mutant and its stimulation by a protein factor.", "content": "Unprimed glucan biosynthesis by a particulate ADP-glucose-glucan glucosyl transferase from an Escherichia coli mutant and its stimulation by a protein factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205908"} {"pmid": "4205909", "title": "Methylation of 4-thio-2'-deoxyuridylate by thymidylate synthetase.", "content": "Methylation of 4-thio-2'-deoxyuridylate by thymidylate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205909"} {"pmid": "4205910", "title": "Rat serum albumin biosynthesis: evidence for a precursor.", "content": "Rat serum albumin biosynthesis: evidence for a precursor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205910"} {"pmid": "4205927", "title": "Clearance rate of exogenous 3H-thymidine from the plasma of pregnant rhesus monkeys.", "content": "Clearance rate of exogenous 3H-thymidine from the plasma of pregnant rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205927"} {"pmid": "4205928", "title": "Beta trace protein. Purification and urinary excretion studies in selected diseases.", "content": "Beta trace protein. Purification and urinary excretion studies in selected diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205928"} {"pmid": "4205929", "title": "Quantitative determination of IgE by single radial immunodiffusion. A comparison of three different methods for intensification of precipitates.", "content": "Quantitative determination of IgE by single radial immunodiffusion. A comparison of three different methods for intensification of precipitates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205929"} {"pmid": "4205930", "title": "Significance of C-reactive protein binding by lecithin: a simplified procedure for CRP isolation.", "content": "Significance of C-reactive protein binding by lecithin: a simplified procedure for CRP isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205930"} {"pmid": "4205931", "title": "Analytical characterization of the urinary proteins from sixty patients with monoclonal gammopathies.", "content": "Analytical characterization of the urinary proteins from sixty patients with monoclonal gammopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205931"} {"pmid": "4205932", "title": "A major role of the fifth component of complement (C5) in the opsonization of yeast particles. Partial dichotomy of function and immunochemical measurement.", "content": "A major role of the fifth component of complement (C5) in the opsonization of yeast particles. Partial dichotomy of function and immunochemical measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205932"} {"pmid": "4205934", "title": "Case report. Diverticulum of pharyngoesophageal junction.", "content": "Case report. Diverticulum of pharyngoesophageal junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205934"} {"pmid": "4205933", "title": "Nutrition and cell growth.", "content": "Nutrition and cell growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205933"} {"pmid": "4205936", "title": "Studies on the catalytic mechanism of a serine protease from Streptomyces griseus.", "content": "Studies on the catalytic mechanism of a serine protease from Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205936"} {"pmid": "4205937", "title": "Competition in Drosophila. 3. A possible maternal effect.", "content": "Competition in Drosophila. 3. A possible maternal effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205937"} {"pmid": "4205935", "title": "Murein hydrolases in the envelope of Escherichia coli. Properties in situ and solubilization from the envelope.", "content": "Murein hydrolases in the envelope of Escherichia coli. Properties in situ and solubilization from the envelope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205935"} {"pmid": "4205938", "title": "Succession & stratification of organisms in sewage oxidation pond.", "content": "Succession & stratification of organisms in sewage oxidation pond.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205938"} {"pmid": "4205939", "title": "Cytological effect of versene on the production of dicentric bridges in spermatocytic chromosomes of grasshopper, Spathosternum prasiniferum Walker.", "content": "Cytological effect of versene on the production of dicentric bridges in spermatocytic chromosomes of grasshopper, Spathosternum prasiniferum Walker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205939"} {"pmid": "4205940", "title": "Characterisation & identification of two aerobic spore forming bacteria producing extracellular glutamic acid & valine respectively.", "content": "Characterisation & identification of two aerobic spore forming bacteria producing extracellular glutamic acid & valine respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205940"} {"pmid": "4205941", "title": "Staphylococcal enterotoxin synthesis during the exponential, transitional, and stationary growth phases.", "content": "Staphylococcal enterotoxin synthesis during the exponential, transitional, and stationary growth phases. Small inocula (1 to 10 colony-forming units per ml of broth) of Staphylococcus aureus strains S-6, S-6R, and FRI-100 were employed to study growth and enterotoxin synthesis in 4% protein hydrolysate powder broths. For each strain, the exponential growth phase ended once the population approached 10(9) to 2 x 10(9) colony-forming units per ml. By that time, the concentrations of enterotoxins A and B reached the minimal level (1 to 2 mug/ml) at which the single gel diffusion tube method becomes applicable. By microslides and reverse passive hemagglutination, enterotoxins A and B were found to be synthesized during the exponential growth phase, but at different exponential rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205941"} {"pmid": "4205943", "title": "Eperythrozoon coccoides. II. Effect on interferon production and role of humoral antibody in host resistance.", "content": "Eperythrozoon coccoides. II. Effect on interferon production and role of humoral antibody in host resistance. Eperythrozoon coccoides was shown to inhibit the interferon response in mice only during the first 3 weeks after acute infection. By 6 weeks the production of interferon in response to Newcastle disease virus returned to a normal level. Antibody to E. coccoides could be demonstrated by three methods: (i) neutralization, (ii) indirect fluorescent antibody, and (iii) gel diffusion. The clearance of the parasitemia could be correlated with the appearance of circulating antibody. The critical role of humoral antibody was confirmed by evidence that immunosuppressive therapy prevented, in an infected animal, clearing of E. coccoides from the blood and converted a nonlethal infection to one with a 100% mortality. Administration of immune serum to the E. coccoides-infected, immunosuppressed animal, however, resulted in clearing of the parasitemia and prevention of death. Finally, a series of immunosuppressive regimens failed to exacerbate E. coccoides in animals after recovery from the acute phase of infection. E. coccoides may not be as important a laboratory contaminant as postulated originally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205943"} {"pmid": "4205942", "title": "Peptic digestion of streptococcal M protein. I. Effect of digestion at suboptimal pH upon the biological and immunochemical properties of purified M protein extracts.", "content": "Peptic digestion of streptococcal M protein. I. Effect of digestion at suboptimal pH upon the biological and immunochemical properties of purified M protein extracts. Purified streptococcal M protein vaccines often produce non-type-specific immunotoxic reactions in the skin or the blood of humans. In an attempt to free the type-specific M antigen (TSM) of such non-type-specific (NTSM) immunotoxic properties, purified M protein preparations were subjected to brief periods (5 to 10 min) of enzymatic digestion in dilute solutions of pepsin (20 mug/ml) at pH 5.0. Such peptic digestion abolished the ability of M protein to aggregate platelets in human platelet-rich plasma and to precipitate plasma fibrinogen. It greatly reduced (up to 16-fold) the capacity of M protein to react with the NTSM complement-fixing antibody that is normally present in human serum. In contrast, it had no effect upon the reactivity of the type-specific M antigen; the pepsin-treated M protein retained its ability to inhibit type-specific streptococcal opsonization by homologous M antibody, and, moreover, retained its ability to elicit type-specific opsonic antibody responses in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205942"} {"pmid": "4205944", "title": "Antibody-mediated inhibition of dextran-sucrose-induced agglutination of Streptococcus mutans.", "content": "Antibody-mediated inhibition of dextran-sucrose-induced agglutination of Streptococcus mutans. Immune sera to strains of Streptococcus mutans were found to inhibit agglutination of bacterial suspensions to which either high-molecular-weight dextran or sucrose was added. This inhibitory activity was shown to be mediated by antibody of the immunoglobulin G class. A semiquantitative assay was developed which demonstrated cross-inhibition of dextran/sucrose-induced agglutination among several strains of S. mutans. Antiserum to a partially purified glucosyltransferase was found to lack agglutination inhibition activity, consistent with the hypothesis that the dextran-binding antigen detected by the assay is immunologically distinct from the glucan-synthetic enzyme. A model for glucan synthesis and binding consistent with the reported data is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205944"} {"pmid": "4205945", "title": "Development of a purified cholera toxoid. I. Purification of toxin.", "content": "Development of a purified cholera toxoid. I. Purification of toxin. The enterotoxin from Vibrio cholerae is selectively concentrated from cell-free culture supernatant by co-precipitation with hexametaphosphate and is further purified by adsorption on aluminum hydroxide powder. The bulk of residual somatic antigen becomes insoluble upon lyophilization of the toxin preparation and is removed by centrifugation of the rehydrated material. Other contaminants are eliminated by treatment with activated carbon. Preparations of toxin, purified by this method, have been characterized by: (i) a single immunoprecipitin line against polyvalent antisera; (ii) homogeneity on acrylamide gels; (iii) specific activities on the order of 22 limit-of-bluing doses/mug; (iv) ultraviolet spectra characteristic of pure protein; and (v) overall yields on the order of 50%, irrespective of purification scale. Such preparations, however, have been shown to contain trace amounts of somatic antigen when they are intensively tested either for their ability to elevate serum vibriocidal antibody titers in immunized rabbits or for their ability to increase resistance of immunized mice to live vibrio challenge. In the latter test system, the level of residual somatic antigen per 50 mug of toxin (toxoid) antigen generally did not exceed 0.025% of the Division of Biological Standards reference vaccine, V. cholerae Inaba IN-12. Methods for elimination of this small amount of somatic antigen have been investigated and are discussed. The particular combination of purification steps which are presently described have been easily and reproducibly applied on a production scale to prepare gram amounts of toxin with a high degree of purity, even under a variety of initial conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205945"} {"pmid": "4205946", "title": "Development of a purified cholera toxoid. II. Preparation of a stable, antigenic toxoid by reaction of purified toxin with glutaraldehyde.", "content": "Development of a purified cholera toxoid. II. Preparation of a stable, antigenic toxoid by reaction of purified toxin with glutaraldehyde. Evidence is presented which confirms that cholera toxoids obtained by reaction of purified toxin with Formalin possess the ability to partially reactivate both in vivo and in vitro. At the same time, conditions are presented for the preparation of stable, antigenic cholera toxoids by reaction of purified toxin with glutaraldehyde. Treatment of purified cholera toxin with approximately 200 mol of glutaraldehyde per mol of toxin at pH 7.8 reproducibly resulted in the preparation of toxoids which: (i) possessed less than 20 bluing doses per 100 mug; (ii) did not reactivate in vivo or in vitro; (iii) precipitated with, and neutralized antitoxin; (iv) elevated prolonged serum antitoxin in immunized rabbits; (v) protected immunized guinea pigs against toxin skin challenge; and (vi) lent themselves to enhanced antigenicity by means of an in situ adjuvant system which may be suitable for man. Acrylamide gel electrophoresis and molecular sieve chromatography of a series of glutaraldehyde-derived toxoids suggested that the reaction products consisted of monomeric and polymeric species and that the proportion of higher-molecular-weight species was determined by the relative concentrations of toxin and glutaraldehyde. The results suggested a relationship between complete and irreversible elimination of toxicity and the formation of higher-molecular-weight toxoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205946"} {"pmid": "4205947", "title": "Vi antigen from Salmonella typhosa and immunity against typhoid fever. I. Isolation and immunologic properties in animals.", "content": "Vi antigen from Salmonella typhosa and immunity against typhoid fever. I. Isolation and immunologic properties in animals. The role of Vi antigen in human immunity against typhoid fever has been debated for decades. Circumstantial evidence indicates that Vi antigen may play a role in pathogenicity and immunity. A Vi preparation was isolated from Salmonella typhosa, the causative organism in human typhoid fever, by a mild precipitation method. It was significantly more potent in animal studies than preparations from Citrobacter used in the past for human study and less toxic than conventional typhoid vaccines. With this antigen, the role of Vi antigen in human protection is now being investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205947"} {"pmid": "4205948", "title": "Relationship of antimicrobial cellular immunity to delayed hypersensitivity in Listeriosis.", "content": "Relationship of antimicrobial cellular immunity to delayed hypersensitivity in Listeriosis. The relationship of antimicrobial cellular immunity to delayed hypersensitivity (DH) was studied in mice antigenically stimulated by living Listeria monocytogenes confined to diffusion chambers in peritoneal cavities or by subcutaneous inoculation of sublethal doses of the organism. Mice showed DH reactions when tested 6 days after inoculation, and reactions were positive for at least 90 days in some mice. DH also became established when the mice were stimulated by antigens diffusing from peritoneal chambers containing viable Listeria. Mice were categorized as DH positive or DH negative if they developed more or less than a 5% increase in foot volume 24 h after the injection of Listeria antigen. Some antigenically stimulated mice did not elicit the DH reaction. Consequently, the animals were arranged as immunized groups (DH positive and DH negative) and Listeria chamber implant groups (DH positive and DH negative). When challenged with L. monocytogenes, all four groups were significantly resistant as compared with controls. Thus, the in vivo tests for immunity and DH did not show direct correlation. The results suggested that antimicrobial cellular immunity can occur as a phenomenon independent of DH. Evidence for antimicrobial cellular immunity as the principle mechanism of resistance in murine listeriosis is discussed with consideration for possible heterogeneity of function by thymus-derived lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205948"} {"pmid": "4205949", "title": "Feline immunoglobulins.", "content": "Feline immunoglobulins. Immunoglobulins (Ig) in feline sera and secretions were identified by immuno-electrophoresis and immunodiffusion with rabbit antisera prepared to feline IgG, IgA, IgM, and whole serum. Adult cat sera, colostral whey, postcolostral sera, tears, and nasal secretions contained IgG, IgA, and IgM. IgG was the only Ig identified in precolostral sera and cerebrospinal fluid. Milk, intestinal contents, pooled allantoic and amniotic fluids, and saliva from adult cats and urine from suckling kittens contained IgG and IgA. Ig were not detected in urine from adult cats. Bile was unique in that IgA and IgM were the predominant Ig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205949"} {"pmid": "4205951", "title": "Biological and physical properties of the suckling mouse cataract agent grown in chicken embryos.", "content": "Biological and physical properties of the suckling mouse cataract agent grown in chicken embryos. Experiments were carried out with the suckling mouse cataract agent (SMCA) in an attempt to better characterize the nature of this agent. Despite the fact that high titers of SMCA were found in the chorioallantoic fluid of inoculated chicken embryos, the agent did not replicate in chicken embryo epithelial cell cultures. SMCA did not interfere with Sindbis virus plaque formation and was not inhibited by chicken interferon or polyinosinic-polycytidylic acid. The agent was relatively resistant to high pH and osmotic shock but was inactivated by low pH. Electron micrographs of negatively stained particles concentrated and semipurified from infected chicken embryo chorioallantoic fluids revealed pleomorphic particles ranging from approximately 70 to 400 nm in diameter. SMCA was resistant to kanamycin, novobiocin, and sodium aurothiomalate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205951"} {"pmid": "4205950", "title": "Mechanism of adherence of Streptococcus mutans to smooth surfaces. II. Nature of the binding site and the adsorption of dextran-levan synthetase enzymes on the cell-wall surface of the streptococcus.", "content": "Mechanism of adherence of Streptococcus mutans to smooth surfaces. II. Nature of the binding site and the adsorption of dextran-levan synthetase enzymes on the cell-wall surface of the streptococcus. The mechanism of adsorption of the Streptococcus mutans enzymes responsible for the synthesis of insoluble dextran-levan to the S. mutans cell-wall binding sites has been studied. Certain characteristics of these binding sites are presented. The adsorption of these enzymes to the cell surface occurred rapidly without the addition of a source of energy and over a pH range of 3 to 11. The adsorption was inhibited by soluble dextran, probably due to the strong affinity of the polymer to the enzyme. All other polymers and sugars studied showed little or no inhibition. The adsorption was also inhibited by antibody globulin to the a-d immunologically specific group antigen surface polysaccharide of S. mutans and by anti-dextran globulin. The inhibition by anti-a-d globulin is considered to be due to a restriction of access of enzyme to the binding site of the enzyme which may be located in close proximity to the group antigen. On the other hand, anti-dextran globulin appeared to directly inhibit the adsorption by covering the binding site. Dextranase destroyed the binding site and released glucose from the S. mutans cells. These data indicate that S. mutans grown in media containing glucose possesses a small amount of dextran on the cell surface, and that this dextran is, or is a part of, the binding site for enzymes which synthesize the insoluble dextran-levan polymer. Trypsin inhibited the synthesis of insoluble polysaccharide and the adherence of cells. It is not clear in this case that destruction of the binding sites occurred. These data present a partial explanation of the processes which may be concerned in the formation of dental plaque on the smooth surfaces of teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205950"} {"pmid": "4205952", "title": "Nonspecific inhibition of growth of intracellular Listeria monocytogenes by lymphocyte culture products.", "content": "Nonspecific inhibition of growth of intracellular Listeria monocytogenes by lymphocyte culture products. Supernatant fluids from mycobacteria-immune and mitogen-stimulated lymphocyte cultures were able to inhibit the intracellular growth of listeria in listeria-infected macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205952"} {"pmid": "4205954", "title": "Maturation-inducing substance in starfishes.", "content": "Maturation-inducing substance in starfishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205954"} {"pmid": "4205953", "title": "Decreased susceptibility to Listeria monocytogenes in mice after infection with Trichinella spiralis.", "content": "Decreased susceptibility to Listeria monocytogenes in mice after infection with Trichinella spiralis. Mice challenged intravenously with Listeria monocytogenes at 7 or 21 days after Trichinella spiralis infection demonstrated a higher mean lethal dose and longer survival time than normal mice. This effect of helminthic infection was abrogated after 49 days.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205953"} {"pmid": "4205955", "title": "Report on drugs, acidic and neutral nitrogenous organics.", "content": "Report on drugs, acidic and neutral nitrogenous organics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205955"} {"pmid": "4205956", "title": "Report on multiresidue methods (interlaboratory studies).", "content": "Report on multiresidue methods (interlaboratory studies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205956"} {"pmid": "4205957", "title": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). II. Catecholamine-containing groups.", "content": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). II. Catecholamine-containing groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205957"} {"pmid": "4205958", "title": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). 3. Serotonin-containing groups.", "content": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). 3. Serotonin-containing groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205958"} {"pmid": "4205959", "title": "The morphology of retinal neurons of the owl monkey Aotes.", "content": "The morphology of retinal neurons of the owl monkey Aotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205959"} {"pmid": "4205960", "title": "A clinical trial of a calculus-inhibitory dentifrice.", "content": "A clinical trial of a calculus-inhibitory dentifrice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205960"} {"pmid": "4205968", "title": "Total replacement of the elbow joint.", "content": "Total replacement of the elbow joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205968"} {"pmid": "4205969", "title": "Porcine congenital infection due to Mycobacterium tuberculosis typus avium.", "content": "Porcine congenital infection due to Mycobacterium tuberculosis typus avium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205969"} {"pmid": "4205970", "title": "Effects of epinephrine and progesterone on the ocular hypertensive response to intravenous infusion of prostaglandin A2.", "content": "Effects of epinephrine and progesterone on the ocular hypertensive response to intravenous infusion of prostaglandin A2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205970"} {"pmid": "4205971", "title": "Pregnancy blockade by indomethacin, an inhibitor of prostaglandin synthesis: its reversal by prostaglandins and progesterone in mice.", "content": "Pregnancy blockade by indomethacin, an inhibitor of prostaglandin synthesis: its reversal by prostaglandins and progesterone in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205971"} {"pmid": "4205972", "title": "Effect of metal-complexing agents on the oxygenase activity of sheep vesicular glands.", "content": "Effect of metal-complexing agents on the oxygenase activity of sheep vesicular glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205972"} {"pmid": "4205973", "title": "Arachidonic acid-induced human platelet aggregation and prostaglandin formation.", "content": "Arachidonic acid-induced human platelet aggregation and prostaglandin formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205973"} {"pmid": "4205974", "title": "The embryo as a transplant.", "content": "The embryo as a transplant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205974"} {"pmid": "4205976", "title": "The selection of teaching-learning materials in health sciences education: report of a WHO study group.", "content": "The selection of teaching-learning materials in health sciences education: report of a WHO study group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205976"} {"pmid": "4205977", "title": "Toxicological evaluation of certain food additives with a review of general principles and of specifications. Seventeenth report of the joint FAO-WHO Expert Committee on Food Additives.", "content": "Toxicological evaluation of certain food additives with a review of general principles and of specifications. Seventeenth report of the joint FAO-WHO Expert Committee on Food Additives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205977"} {"pmid": "4205978", "title": "Drug hydroxylation and glucuronidation in liver microsomes of phenobarbital-treated rats.", "content": "Drug hydroxylation and glucuronidation in liver microsomes of phenobarbital-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205978"} {"pmid": "4205979", "title": "Investigation of the protease forming ability of Serratia marcescens and one of its mutant strains.", "content": "Investigation of the protease forming ability of Serratia marcescens and one of its mutant strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205979"} {"pmid": "4205980", "title": "Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis.", "content": "Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205980"} {"pmid": "4205981", "title": "Mycobacterium tuberculosis strains showing positive iron uptake.", "content": "Mycobacterium tuberculosis strains showing positive iron uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205981"} {"pmid": "4205982", "title": "A cryptic prophage carried by Bacillus cereus.", "content": "A cryptic prophage carried by Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205982"} {"pmid": "4205984", "title": "Serological relationship between Pseudomonas aeruginosa and Enterobacteriaceae. II. Relationship of Pseudomonas aeruginosa O antigens to Escherichia, Shigella, Proteus, Morganella, Rettgerella and Providencia.", "content": "Serological relationship between Pseudomonas aeruginosa and Enterobacteriaceae. II. Relationship of Pseudomonas aeruginosa O antigens to Escherichia, Shigella, Proteus, Morganella, Rettgerella and Providencia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205984"} {"pmid": "4205983", "title": "Whole body counting of 32P-endotoxin elimination in endotoxin-tolerant and control mice.", "content": "Whole body counting of 32P-endotoxin elimination in endotoxin-tolerant and control mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205983"} {"pmid": "4205986", "title": "Simple, sensitive spectrophotofluorometric method for hydrazine in plasma.", "content": "Simple, sensitive spectrophotofluorometric method for hydrazine in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205986"} {"pmid": "4205985", "title": "Life span and fine structural changes in oxygen-poisoned Drosophila melanogaster.", "content": "Life span and fine structural changes in oxygen-poisoned Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205985"} {"pmid": "4205987", "title": "Application of the carbon cup atomisation technique in water analysis by atomic-absorption spectroscopy.", "content": "Application of the carbon cup atomisation technique in water analysis by atomic-absorption spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205987"} {"pmid": "4205988", "title": "Synthesis of valinomycin by the phosphite method.", "content": "Synthesis of valinomycin by the phosphite method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4205988"} {"pmid": "4206020", "title": "Effects of calcium and strontium on divalent ion content of refractive granules in Tetrahymena pyriformis.", "content": "Effects of calcium and strontium on divalent ion content of refractive granules in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206020"} {"pmid": "4206022", "title": "Observations on alternative health strategies.", "content": "Observations on alternative health strategies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206022"} {"pmid": "4206021", "title": "Role of specific sperm antigens in fertilization.", "content": "Role of specific sperm antigens in fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206021"} {"pmid": "4206023", "title": "Blood bank inventory policies: a computer simulation.", "content": "Blood bank inventory policies: a computer simulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206023"} {"pmid": "4206024", "title": "Analysis of multiple sources of variation: comparison of three techniques.", "content": "Analysis of multiple sources of variation: comparison of three techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206024"} {"pmid": "4206025", "title": "Isolation of an acidic surface antigen from a conventional strain of Staphylococcus aureus.", "content": "Isolation of an acidic surface antigen from a conventional strain of Staphylococcus aureus. Staphylococcus aureus strain 7007, a prototype isolated from a hospital burn unit, was shown to exhibit a significant degree of resistance to ingestion by mouse polymorphonuclear leukocytes. An acidic surface antigen was isolated from strain 7007 by a combination of 10% trichloroacetic acid extraction, ion-exchange chromatography, and gel filtration. Chemical analysis indicated that the surface antigen consists of an unknown aminouronic acid and an amino sugar. Immunochemical analysis suggested that the 7007 antigen is a common feature of all the strains collected from the burn unit. No cross-reactivity was observed between the carbohydrate preparations of various hospital staphylococcal strains and the 7007 heteropolymer. These results suggested the possibility that the surface antigen of strain 7007 represents a strain- or type-specific antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206025"} {"pmid": "4206026", "title": "Effects of carbon dust inhalation on the cell-mediated immune response in mice.", "content": "Effects of carbon dust inhalation on the cell-mediated immune response in mice. The effects of carbon dust inhalation on the bone marrow-derived (B) and thymus-derived (T) lymphocyte populations of spleen and mediastinal lymph node (MLN) cultures were examined. The concanavalin A (Con A)-responsive cell population (T cells) in the spleen was found to be depressed after 7 days of pre-exposure to carbon dust. However, this effect was transient, and after 14, 21, and 28 days of pre-exposure to carbon dust, the Con A-responsive cells exhibited a 30 to 40% enhancement over control group responses. Conversely, Con A-responsive cells in the pooled MLN cultures exhibited depression, ranging from 22 to 33% below control group values, after 7, 14, and 28 days of pre-exposure to carbon dust. The lipopolysaccharide (LPS)-responsive cell population (B cells) in the spleens of carbon-exposed mice was found not to differ significantly from control group values after all times of pre-exposure. LPS-responsive cells in the MLN cultures exhibited enhancement, ranging from 49 to 74% above control values, after 14, 21, and 28 days of pre-exposure to carbon dust. The ability of carbon spleen cell cultures from carbon-exposed mice to undergo antigen induced blast transformation after sensitization with Mycobacterium tuberculosis H37Ra was also determined. Mice exposed to carbon dust inhalation 2 weeks before and 3 weeks after aerosol or subcutaneous immunization exhibited significantly enhanced ratios of transformation upon culture of their spleen lymphocytes with purified protein derivative of tuberculin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206026"} {"pmid": "4206018", "title": "The familial nephrotic syndrome. II. A clinicopathological study.", "content": "The familial nephrotic syndrome. II. A clinicopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206018"} {"pmid": "4206017", "title": "Editorial: home dialysis or transplantation.", "content": "Editorial: home dialysis or transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206017"} {"pmid": "4206028", "title": "Stability of the rabbit immunogenic marker of RA 27-3 rubella vaccine virus after human passage.", "content": "Stability of the rabbit immunogenic marker of RA 27-3 rubella vaccine virus after human passage. Rabbits were inoculated intravenously with \"wild\" rubella virus, RA 27/3 rubella vaccine virus, or rubella virus isolated from recipients of RA 27/3 vaccine. Rabbits receiving \"wild\" virus developed rubella hemagglutination inhibition antibody, and those receiving vaccine virus did not. One of the five reisolates tested produced a low transient antibody response in two of the five rabbits inoculated with this strain. The study indicates that the rabbit immunogenic marker after intravenous injection can be used to determine if a rubella virus isolated from a patient is of \"wild\" or vaccine origin. There was no significant change in the reduced immunogenicity characteristics of the RA 27/3 vaccine virus after human passage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206028"} {"pmid": "4206027", "title": "Pseudomonas aeruginosa exotoxin in mice: localization and effect on protein synthesis.", "content": "Pseudomonas aeruginosa exotoxin in mice: localization and effect on protein synthesis. We studied the fate of (125)I-labeled Pseudomonas aeruginosa (PA 103) exotoxin injected intravenously into mice and the effect of the exotoxin on the protein synthesis of various organs. After 2 h, only 5% of the injected label remained in the blood, in comparison with 30% of the injected control, consisting of [(125)I]bovine serum albumin. The highest concentration of radioactivity was consistently observed in the kidneys of toxin-treated mice. Lesser amounts of the label were found in the liver and the spleen. The heart, pancreas, lung, and brain showed very little uptake. Approximately 30% of the label (non-trichloroacetic acid precipitable) was recovered from the urine within 2 h after the injection. The behavior of [(125)I]toxoid was similar to that of the [(125)I]toxin. In contrast, in [(125)I]bovine serum albumin-treated mice, the label was uniformly distributed among the organs examined, and the concentration was low. After intravenous administration of the exotoxin, a 50% inhibition of protein synthesis was observed in the liver within 4 h, and virtually complete inhibition was observed shortly before the time of death. Kidney and spleen displayed slight reduction of protein synthesis at 2 to 4 h and approximately 50% reduction during the terminal stage. It appeared that the highest concentration of the toxin occurred in the kidney, where it was degraded, but its greatest toxic effect took place in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206027"} {"pmid": "4206029", "title": "Immunological study of the heat-labile enterotoxins of Escherichia coli and Vibrio cholerae.", "content": "Immunological study of the heat-labile enterotoxins of Escherichia coli and Vibrio cholerae. Immunodiffusion experiments were conducted to associate a precipitin line with Escherichia coli heat-labile enterotoxin (LT). Wild strains of porcine and of human enteropathogenic E. coli as well as laboratory-derived enterotoxigenic variants of E. coli K-12 were used for LT antigen preparations. These were produced mainly by ultrafiltration and ammonium sulfate precipitation of broth culture supernatants. When antisera with anti-LT activity were reacted with antigen preparations from Ent(+) and Ent(-) variants of E. coli K-12, a line \"a\" was given by Ent(+) but not by Ent(-) preparations. Line \"a\" was removed by absorption of anti-LT serum with antigen preparation from an Ent(+)E. coli K-12, but was unaffected when the antigen preparation used to absorb the serum was from an Ent(-)E. coli K-12. A line identical to \"a\" was given by antigen preparations from wild strains of porcine enteropathogenic E. coli reacted with homologous or heterologous anti-LT sera. One human strain of enteropathogenic E. coli was shown to possess an antigen identical to that which gave rise to line \"a.\" To demonstrate this line it was necessary to use high concentrations of gammaglobulin and high concentrations of the crude antigen preparations. LT preparations reacted with anticholera toxin to give a line \"c,\" which showed a reaction of partial identity with line \"b\" produced by reaction of pure choleragenoid and anticholera toxin. Lines \"a\" and \"c\" gave reactions of identity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206029"} {"pmid": "4206019", "title": "Growth in children with renal disease with particular reference to the effects of calorie malnutrition: a review.", "content": "Growth in children with renal disease with particular reference to the effects of calorie malnutrition: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206019"} {"pmid": "4206030", "title": "Mechanisms of immunity in typhus infections. IV. Failure of chicken embryo cells in culture to restrict growth of antibody-sensitized Rickettsia prowazeki.", "content": "Mechanisms of immunity in typhus infections. IV. Failure of chicken embryo cells in culture to restrict growth of antibody-sensitized Rickettsia prowazeki. Rickettsia prowazeki, pretreated with typhus immune human serum, readily infects, and grows in, chicken embryo cells in culture. This finding is similar to those of previous studies which showed that typhus rickettsiae, pretreated with immune serum, grow in cells of the yolk sac of embryonated hen eggs and in the cells of the midgut of the human body louse. In contrast, identically treated typhus rickettsiae were destroyed by human macrophages in culture. Collectively, these observations seem to support an emerging concept that the fate of antibody-sensitized typhus rickettsiae depends upon the presence or absence of certain specialized properties of the host cell into which they gain entrance-nonphagocytic cells or \"nonprofessional\" phagocytic cells versus certain kinds of \"professional\" phagocytes. The phenomena involved probably have an important bearing on the mechanisms of the persisting infection and the nonsterile immunity which characterizes convalescence from typhus fever in man. They also form the basis for certain practical technical innovations in the laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206030"} {"pmid": "4206032", "title": "The densities of colloidal iron hydroxide particles bound to microvilli and the spaces between them: studies on glutaraldehyde-fixed Ehrlich ascites tumour cells.", "content": "The densities of colloidal iron hydroxide particles bound to microvilli and the spaces between them: studies on glutaraldehyde-fixed Ehrlich ascites tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206032"} {"pmid": "4206033", "title": "An examination into the phenomenon of granulation, in mu particles of stock 540 Paramecium aurelia.", "content": "An examination into the phenomenon of granulation, in mu particles of stock 540 Paramecium aurelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206033"} {"pmid": "4206038", "title": "Filamentous bacterial viruses. XI. Molecular architecture of the class II (Pf1, Xf) virion.", "content": "Filamentous bacterial viruses. XI. Molecular architecture of the class II (Pf1, Xf) virion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206038"} {"pmid": "4206036", "title": "Hexachlorophene and the food and drug administration.", "content": "Hexachlorophene and the food and drug administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206036"} {"pmid": "4206031", "title": "Changes in the scintigraphic aspects of liver after partial high-energy irradiation.", "content": "Changes in the scintigraphic aspects of liver after partial high-energy irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206031"} {"pmid": "4206035", "title": "Review of the toxicity of hexachlorophene, including its neurotoxicity.", "content": "Review of the toxicity of hexachlorophene, including its neurotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206035"} {"pmid": "4206037", "title": "Hexachlorophene in perspective.", "content": "Hexachlorophene in perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206037"} {"pmid": "4206051", "title": "Cationic leukocyte antigen in urine of patients with chronic myelocytic leukaemia.", "content": "Cationic leukocyte antigen in urine of patients with chronic myelocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206051"} {"pmid": "4206053", "title": "The significance of protein disulfide and sulfhydryl groups in prostaglandin action.", "content": "The significance of protein disulfide and sulfhydryl groups in prostaglandin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206053"} {"pmid": "4206054", "title": "Measurement of prostaglandin f-2 alpha metabolites by radioimmunoassay.", "content": "Measurement of prostaglandin f-2 alpha metabolites by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206054"} {"pmid": "4206055", "title": "An inhibitor of the action of prostaglandins in sheep and human semen.", "content": "An inhibitor of the action of prostaglandins in sheep and human semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206055"} {"pmid": "4206061", "title": "Growth of Theileria parva-infected bovine lymphoid cells in whole-body irradiated mice.", "content": "Growth of Theileria parva-infected bovine lymphoid cells in whole-body irradiated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206061"} {"pmid": "4206052", "title": "Treatment of infective endocarditis--1973.", "content": "Treatment of infective endocarditis--1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206052"} {"pmid": "4206066", "title": "Proceedings: Radiation treatment of carcinoma of the nasal vestibule.", "content": "Proceedings: Radiation treatment of carcinoma of the nasal vestibule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206066"} {"pmid": "4206067", "title": "Proceedings: Electron beam therapy of head and neck tumors.", "content": "Proceedings: Electron beam therapy of head and neck tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206067"} {"pmid": "4206068", "title": "Proceedings: Time dose factors in radiation induced osteitis.", "content": "Proceedings: Time dose factors in radiation induced osteitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206068"} {"pmid": "4206069", "title": "Proceedings: Experimental verification of a method for varying the effective angle of wedge filters.", "content": "Proceedings: Experimental verification of a method for varying the effective angle of wedge filters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206069"} {"pmid": "4206070", "title": "Serologic studies in farmer's lung. Precipitins to the thermophilic actinomycetes.", "content": "Serologic studies in farmer's lung. Precipitins to the thermophilic actinomycetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206070"} {"pmid": "4206071", "title": "Primary meningococcal pneumonia.", "content": "Primary meningococcal pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206071"} {"pmid": "4206072", "title": "Possibilities and limitations of delegated literature searches by computer.", "content": "Possibilities and limitations of delegated literature searches by computer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206072"} {"pmid": "4206073", "title": "A variation of the sulfide contraction procedure for synthesis of corrinoid systems.", "content": "A variation of the sulfide contraction procedure for synthesis of corrinoid systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206073"} {"pmid": "4206074", "title": "Formation of a 1-hydroxycorrin complex by photochemical A-D-secocorrin leads to corrin cycloisomerization.", "content": "Formation of a 1-hydroxycorrin complex by photochemical A-D-secocorrin leads to corrin cycloisomerization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206074"} {"pmid": "4206075", "title": "Photographing specimens immersed in fluid.", "content": "Photographing specimens immersed in fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206075"} {"pmid": "4206076", "title": "Brain permeability of water.", "content": "Brain permeability of water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206076"} {"pmid": "4206077", "title": "A monoclonal IgM with antibodylike specificity for phospholipids in a patient with lymphoma.", "content": "A monoclonal IgM with antibodylike specificity for phospholipids in a patient with lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206077"} {"pmid": "4206078", "title": "Plasma cell dyscrasia associated with the production of incomplete (?deleted) IgGlambda molecules, gamma heavy chains, and free lambda chains containing carbohydrate: description of the first case.", "content": "Plasma cell dyscrasia associated with the production of incomplete (?deleted) IgGlambda molecules, gamma heavy chains, and free lambda chains containing carbohydrate: description of the first case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206078"} {"pmid": "4206079", "title": "Cerebrovascular Moyamoya disease.", "content": "Cerebrovascular Moyamoya disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206079"} {"pmid": "4206080", "title": "Insulin and growth hormone secretion in rats with ventromedial hypothalamic lesions maintained on restricted food intake.", "content": "Insulin and growth hormone secretion in rats with ventromedial hypothalamic lesions maintained on restricted food intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206080"} {"pmid": "4206081", "title": "Insulin degradation. IX. On the presence of glutathione-insulin transhydrogenase in human leukocytes.", "content": "Insulin degradation. IX. On the presence of glutathione-insulin transhydrogenase in human leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206081"} {"pmid": "4206082", "title": "Sodium retention accompanying insulin treatment of diabetes mellitus.", "content": "Sodium retention accompanying insulin treatment of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206082"} {"pmid": "4206083", "title": "Kinetic studies of levansucrase of Bacillus subtilis.", "content": "Kinetic studies of levansucrase of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206083"} {"pmid": "4206084", "title": "Phasing effects of light on cell division in exponentially increasing cultures of Tetrahymena grown at low temperatures.", "content": "Phasing effects of light on cell division in exponentially increasing cultures of Tetrahymena grown at low temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206084"} {"pmid": "4206085", "title": "Interactions of retinol-binding protein with various chromophores and with thyroxine-binding protein. A model for visual pigments.", "content": "Interactions of retinol-binding protein with various chromophores and with thyroxine-binding protein. A model for visual pigments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206085"} {"pmid": "4206086", "title": "Monographs on fragrance raw materials.", "content": "Monographs on fragrance raw materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206086"} {"pmid": "4206087", "title": "Toxicology: cost-time.", "content": "Toxicology: cost-time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206087"} {"pmid": "4206088", "title": "The relative susceptibility of four cephalosporins to a beta-lactamase from Bacillus cereus.", "content": "The relative susceptibility of four cephalosporins to a beta-lactamase from Bacillus cereus. The effects of purified beta-lactamase from Bacillus cereus on the activity of four cephalosporins are described. Drug inactivation was measured spectrophotometrically and confirmed by microbiological assay and by microbiological techniques involving determinations of minimum inhibitory concentrations and growth curves of Staphylococcus aureus NCTC 6571 (Oxford) in broth containing drug +/- enzyme. Cephaloridine was the most sensitive of the four cephalosporins, followed by cephalothin and the sodium salt of 7-cyanacetamidocephalosporanic acid, with cephalexin considerably resistant to inactivation. The possible use of this beta-lactamase in the sterility testing of cephaloridine and cephalothin is examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206088"} {"pmid": "4206089", "title": "Social rank, observability, and sexual behaviour of rhesus monkeys (Macaca mulatta).", "content": "Social rank, observability, and sexual behaviour of rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206089"} {"pmid": "4206090", "title": "Letter: Lymphoma and anticonvulsive therapy.", "content": "Letter: Lymphoma and anticonvulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206090"} {"pmid": "4206091", "title": "Supraventricular arrhythmias caused by parenteral hyperalimentation.", "content": "Supraventricular arrhythmias caused by parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206091"} {"pmid": "4206092", "title": "Absence of concurrent permeability changes of intestinal mucosa in association with cholera toxin-induced secretion.", "content": "Absence of concurrent permeability changes of intestinal mucosa in association with cholera toxin-induced secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206092"} {"pmid": "4206097", "title": "Letter: Asymptomatic gonorrhea in men.", "content": "Letter: Asymptomatic gonorrhea in men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206097"} {"pmid": "4206095", "title": "Protein nutrition and liver disease after jejunoileal bypass for morbid obesity.", "content": "Protein nutrition and liver disease after jejunoileal bypass for morbid obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206095"} {"pmid": "4206096", "title": "Editorial: Somatostatin: newcomer from the hypothalamus.", "content": "Editorial: Somatostatin: newcomer from the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206096"} {"pmid": "4206098", "title": "Letter: Range of normal serum magnesium values.", "content": "Letter: Range of normal serum magnesium values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206098"} {"pmid": "4206099", "title": "Effect of thyrotropin releasing hormone (TRH) on the menstrual cycle in women.", "content": "Effect of thyrotropin releasing hormone (TRH) on the menstrual cycle in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206099"} {"pmid": "4206100", "title": "Some thoughts on assessing the effectiveness of passive immunization to Rh.", "content": "Some thoughts on assessing the effectiveness of passive immunization to Rh. In 1000 Rh-negative women who are delivered of Rh-positive fetuses and receive passive immunity postpartum, there will be 5-10 failures to protect against sensitization. Studies have been conducted to find out possible explanations for the failures and to devise means of preventing some or all of them. Results from the investigations indicate that if all postabortal and postpartum patients at risk receive anti-D immune globulin and are carefully screened for large fetomaternal bleeds by the use of direct counting of fetal red cells in the maternal circulation, the number of failures to protect against Rh sensitization can be reduced to an undiminishable minimum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206100"} {"pmid": "4206101", "title": "Amniotic fluid alpha-fetoprotein in anencephaly.", "content": "Amniotic fluid alpha-fetoprotein in anencephaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206101"} {"pmid": "4206106", "title": "Evaluation of a latex agglutination test for amoebiasis.", "content": "Evaluation of a latex agglutination test for amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206106"} {"pmid": "4206107", "title": "Immunization of monkeys against a recently isolated human strain of Trypanosoma rhodesiense by use of gamma irradiation.", "content": "Immunization of monkeys against a recently isolated human strain of Trypanosoma rhodesiense by use of gamma irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206107"} {"pmid": "4206108", "title": "Antigenic variation in cyclically transmitted isolates of Trypanosoma gambiense.", "content": "Antigenic variation in cyclically transmitted isolates of Trypanosoma gambiense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206108"} {"pmid": "4206109", "title": "Immunoglobulins in bovine trypanosomiasis.", "content": "Immunoglobulins in bovine trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206109"} {"pmid": "4206110", "title": "Serum protein changes in trypanosomiasis in cattle.", "content": "Serum protein changes in trypanosomiasis in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206110"} {"pmid": "4206111", "title": "Experimental Trypanosoma cruzi infections in Erthrocebus patas.", "content": "Experimental Trypanosoma cruzi infections in Erthrocebus patas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206111"} {"pmid": "4206112", "title": "The capillary-tube agglutination (CA) test. A proposed aid for the diagnosis of trypanosomiasis in the field.", "content": "The capillary-tube agglutination (CA) test. A proposed aid for the diagnosis of trypanosomiasis in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206112"} {"pmid": "4206113", "title": "Serological studies on strains of Trypanosoma vivax.", "content": "Serological studies on strains of Trypanosoma vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206113"} {"pmid": "4206114", "title": "Domestic risk factor--an attempt to assess risk of infection with Trypanosoma cruzi in houses in Brazil.", "content": "Domestic risk factor--an attempt to assess risk of infection with Trypanosoma cruzi in houses in Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206114"} {"pmid": "4206115", "title": "The host selection pattern and infection rates of Panstrongylus megistus in an area of eastern Brazil.", "content": "The host selection pattern and infection rates of Panstrongylus megistus in an area of eastern Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206115"} {"pmid": "4206116", "title": "Isolation of a non-haemadsorbing strain of African swine fever (ASF) virus from a natural outbreak of the disease.", "content": "Isolation of a non-haemadsorbing strain of African swine fever (ASF) virus from a natural outbreak of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206116"} {"pmid": "4206117", "title": "Experimental Sarcoptes scabiei infection in pigs: clinical signs and significance of infection.", "content": "Experimental Sarcoptes scabiei infection in pigs: clinical signs and significance of infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206117"} {"pmid": "4206118", "title": "Comparative studies on tomato aspermy and cucumber mosaic viruses. I. Physical and chemical properties.", "content": "Comparative studies on tomato aspermy and cucumber mosaic viruses. I. Physical and chemical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206118"} {"pmid": "4206119", "title": "Prenatal screening in the serodiagnosis of blood group sensitization.", "content": "Prenatal screening in the serodiagnosis of blood group sensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206119"} {"pmid": "4206120", "title": "Effect of heparin on the concentration of insulin in serum and plasma.", "content": "Effect of heparin on the concentration of insulin in serum and plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206120"} {"pmid": "4206123", "title": "Pathology of macroglobulinemia--a review of Japanese cases.", "content": "Pathology of macroglobulinemia--a review of Japanese cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206123"} {"pmid": "4206124", "title": "Renal artery stenosis in childhood neurofibromatosis.", "content": "Renal artery stenosis in childhood neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206124"} {"pmid": "4206125", "title": "A cephalometric evaluation of the old Milwaukee brace and the modified Milwaukee brace in relation to the normal growing child.", "content": "A cephalometric evaluation of the old Milwaukee brace and the modified Milwaukee brace in relation to the normal growing child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206125"} {"pmid": "4206126", "title": "Vaccination against Marek's disease with herpes virus of turkeys.", "content": "Vaccination against Marek's disease with herpes virus of turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206126"} {"pmid": "4206127", "title": "Blood vessels of the ciliary ganglion in man.", "content": "Blood vessels of the ciliary ganglion in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206127"} {"pmid": "4206129", "title": "Outbreak of meningococcal disease in Devon.", "content": "Outbreak of meningococcal disease in Devon. In a recent outbreak of 31 cases of meningococcal disease in Devon there were six deaths. Several patients had an unusual rash as the presenting feature and there was an unusually high incidence of complications, affecting the central nervous system, joints, and the heart among other sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206129"} {"pmid": "4206128", "title": "Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis.", "content": "Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis. This paper reports our experience in monitoring gentamicin therapy during the treatment of 68 episodes of serious Gram-negative sepsis in 65 hospital patients. Most of the patients had major underlying disease. Of those who were adequately treated (peak serum concentrations of 5 mug/ml or more in 72 hours for septicaemia, urinary tract infection, and wound infection; and 8 mug/ml or more at some time during the course of treatment for pneumonia) 84% (46 out of 55) were cured. These serum concentrations could be achieved only by starting with a regimen of 5 mg/kg/day in three divided doses in all adult patients, subsequent dosage being determined by the results of rapid serum assay. The incidence of nephrotoxicity and symptomatic ototoxicity was no greater than in previous series. The main reason for assaying serum gentamicin is to ensure that an adequate dosage is achieved as soon as possible. In patients with impaired renal function or receiving prolonged high dosage assays also serve to guard against an excessive accumulation of gentamicin and an increased risk of toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206128"} {"pmid": "4206130", "title": "Letter: Clinical diagnosis of Reye's syndrome.", "content": "Letter: Clinical diagnosis of Reye's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206130"} {"pmid": "4206131", "title": "Mechanism of the formation of concanavalin A-teichoic acid complexes.", "content": "Mechanism of the formation of concanavalin A-teichoic acid complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206131"} {"pmid": "4206133", "title": "Tissue distribution of coenzyme and other forms of vitamin B12 in control subjects and patients with pernicious anaemia.", "content": "Tissue distribution of coenzyme and other forms of vitamin B12 in control subjects and patients with pernicious anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206133"} {"pmid": "4206121", "title": "Letter: Coagulation defects and arteriosclerosis in rabbits induced by diet containing triglycerides.", "content": "Letter: Coagulation defects and arteriosclerosis in rabbits induced by diet containing triglycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206121"} {"pmid": "4206134", "title": "The possible site of action of sodium cromoglycate assessed by exercise challenge.", "content": "The possible site of action of sodium cromoglycate assessed by exercise challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206134"} {"pmid": "4206122", "title": "Familial thyroxine-binding globulin deficiency. A study of three Danish families.", "content": "Familial thyroxine-binding globulin deficiency. A study of three Danish families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206122"} {"pmid": "4206135", "title": "Field studies on the use of coated porous polyurethane plugs as indwelling monitors of organochlorine pesticides and polychlorinated biphenyl contents of streams.", "content": "Field studies on the use of coated porous polyurethane plugs as indwelling monitors of organochlorine pesticides and polychlorinated biphenyl contents of streams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206135"} {"pmid": "4206136", "title": "Evaluation of internal exposure to radionuclides of I, Cs and Co during maintenance operations on primary steam leak in a nuclear power station.", "content": "Evaluation of internal exposure to radionuclides of I, Cs and Co during maintenance operations on primary steam leak in a nuclear power station.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206136"} {"pmid": "4206137", "title": "The fetal uptake of cerium-144-praseodymium-144 after injection of its chelates to pregnant rat.", "content": "The fetal uptake of cerium-144-praseodymium-144 after injection of its chelates to pregnant rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206137"} {"pmid": "4206139", "title": "Experimental amblyopia in monkeys. Further behavioral observations and clinical correlations.", "content": "Experimental amblyopia in monkeys. Further behavioral observations and clinical correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206139"} {"pmid": "4206138", "title": "On prognosis and treatment of acute severe pancreatitis with severe uremia.", "content": "On prognosis and treatment of acute severe pancreatitis with severe uremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206138"} {"pmid": "4206140", "title": "Histological studies of the visual system in monkeys with experimental amblyopia.", "content": "Histological studies of the visual system in monkeys with experimental amblyopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206140"} {"pmid": "4206141", "title": "Soybean protein flavor components: a review.", "content": "Soybean protein flavor components: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206141"} {"pmid": "4206142", "title": "Fatty acid derivatives and glycolipids in high-protein bakery products.", "content": "Fatty acid derivatives and glycolipids in high-protein bakery products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206142"} {"pmid": "4206143", "title": "Neurophysiologic and behavioral toxicologic testing to detect subclinical neurologic alterations induced by environmental toxicants.", "content": "Neurophysiologic and behavioral toxicologic testing to detect subclinical neurologic alterations induced by environmental toxicants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206143"} {"pmid": "4206144", "title": "Efferent connections of the red nucleus in the brainstem and spinal cord of the Rhesus monkey.", "content": "Efferent connections of the red nucleus in the brainstem and spinal cord of the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206144"} {"pmid": "4206146", "title": "A combined fluorescence histochemical and electron microscopic method for studying special monoamine-containing cells (SIF cells).", "content": "A combined fluorescence histochemical and electron microscopic method for studying special monoamine-containing cells (SIF cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206146"} {"pmid": "4206148", "title": "Effect of oral alanine on blood beta-hydroxybutyrate and plasma glucose, insulin, free fatty acids, and growth hormone in normal and diabetic subjects.", "content": "Effect of oral alanine on blood beta-hydroxybutyrate and plasma glucose, insulin, free fatty acids, and growth hormone in normal and diabetic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206148"} {"pmid": "4206145", "title": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). IV. An atlas.", "content": "Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). IV. An atlas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206145"} {"pmid": "4206147", "title": "The local antibody response to R.S. virus infection in the respiratory tract.", "content": "The local antibody response to R.S. virus infection in the respiratory tract. Nasopharyngeal secretions were taken during the acute phase of illness from 66 infants and children admitted to hospital with lower respiratory tract infections. Second secretions were taken, after an interval of 7 days, from 33 of these patients. A significant increase in neutralizing activity to R.S. virus was demonstrated in the nasopharyngeal secretions of patients in response to severe R.S. virus infection. Seventeen out of 25 patients (68%) with R.S. virus infections developed a rise in secretory neutralizing titre, compared with only 1 out of 8 patients (13%) with respiratory infections not involving R.S. virus.A high titre of secretory neutralizing activity was found more often in the acute phase of illness in patients with R.S. virus infections, especially bronchiolitis, than in patients with respiratory infections not involving R.S. virus. Fifteen out of 34 patients (44%) with R.S. virus bronchiolitis were found to possess a neutralizing titre of (1/4) or more in their first secretions, compared with 4 out of 12 patients (33%) with R.S. virus infections other than bronchiolitis and 3 out of 20 patients (15%) with respiratory infections not involving R.S. virus.A quantitative analysis of the immunoglobulins present in the secretions indicated that IgA was the only immunoglobulin consistently present at a detectable concentration. The geometric mean values of IgA, IgM and IgG in the secretions examined were found to be 22.3, 4.3 and 5.3 mg./100 ml. respectively.The neutralizing activity against R.S. virus, present in the secretions, was shown to be due to specific IgA antibody. This was accomplished by removing the neutralizing activity in two secretions by absorption with anti-IgA serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206147"} {"pmid": "4206149", "title": "Veterinary medicine and surgery in the Republic of Vietnam.", "content": "Veterinary medicine and surgery in the Republic of Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206149"} {"pmid": "4206150", "title": "The melena to admission time: a critical look at the patient with occult gastrointestinal bleeding.", "content": "The melena to admission time: a critical look at the patient with occult gastrointestinal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206150"} {"pmid": "4206151", "title": "Conservation surgery of the larynx and hypopharynx.", "content": "Conservation surgery of the larynx and hypopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206151"} {"pmid": "4206153", "title": "Interface of dental research, federal and civilian.", "content": "Interface of dental research, federal and civilian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206153"} {"pmid": "4206152", "title": "Acute epididymitis in Vietnam: review of 52 cases.", "content": "Acute epididymitis in Vietnam: review of 52 cases. The treatment experience of 52 military personnel in Viet Nam who had their 1st episode of acute epididymitis during a 9-month period in 1970-71 is reviewed. 75% of the patients were ages 18-30. The right side was involved in 48.1% of cases and the left in 44.2%; the remaining 7 cases showed bilateral involvement. Urine analysis revealed pyuria in 36 patients (69.2%). White blood cells in urine were too numerous to count in 20 patients (38.5%). Urine cultures were negative in all but 1 case. The patients were hospitalized a median number of 9 days. The therapeutic regimen consisted of absolute bed rest, elevation of the scrotum, and ice to the scrotum until tenderness disappeared. Tetracycline was generally administered. 28 patients showed no obvious factor related to the etiology or pathogenesis of the epididymitis; however, 3 had gonorrheal urethritis on admission, 7 had had gonorrhea within 8 weeks of admission, 4 had had nongonococcal urethritis within the prior 8 weeks, and 6 had acute or subacute prostatitis on admission. The paradox observed in this series between positive urinalasis and negative urine cultures may be explained by anaerobic and microaerophilic forms of the usual urinary pathogenic bacteria. The frequency of recovery of pathogenic bacteria has been shown to be enhanced when anaerobic and microaerophilic cultures are performed. Antibiotics thus assume an important role in the treatment of acute epididymitis, even if urine cultures are negative by the usual methods. Further research is needed to confirm this hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206152"} {"pmid": "4206154", "title": "Case for diagnosis: a rapidly enlarging mass involving the right maxillary ridge.", "content": "Case for diagnosis: a rapidly enlarging mass involving the right maxillary ridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206154"} {"pmid": "4206155", "title": "The bus case: earliest contact military psychiatry.", "content": "The bus case: earliest contact military psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206155"} {"pmid": "4206156", "title": "An experimental evaluation of a therapeutic community.", "content": "An experimental evaluation of a therapeutic community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206156"} {"pmid": "4206157", "title": "Regional perinatal health centers.", "content": "Regional perinatal health centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206157"} {"pmid": "4206159", "title": "Communication innovations at the mental hygiene consultation service-inpatient psychiatry interface.", "content": "Communication innovations at the mental hygiene consultation service-inpatient psychiatry interface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206159"} {"pmid": "4206158", "title": "A respirator development.", "content": "A respirator development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206158"} {"pmid": "4206161", "title": "Murine typhus in Vietnam.", "content": "Murine typhus in Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206161"} {"pmid": "4206162", "title": "Coronary artery disease: its impact on Naval and Marine Corps personnel.", "content": "Coronary artery disease: its impact on Naval and Marine Corps personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206162"} {"pmid": "4206163", "title": "The use of metronidazole in treating complications of amebiasis.", "content": "The use of metronidazole in treating complications of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206163"} {"pmid": "4206160", "title": "Chemotherapeutic results in a multi-drug resistant strain of Plasmodium falciparum malaria from Vietnam.", "content": "Chemotherapeutic results in a multi-drug resistant strain of Plasmodium falciparum malaria from Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206160"} {"pmid": "4206164", "title": "Pemphigus-like antibodies in sera of patients with thermal burns, gunshot wounds, and skin grafts.", "content": "Pemphigus-like antibodies in sera of patients with thermal burns, gunshot wounds, and skin grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206164"} {"pmid": "4206165", "title": "Ultrasound and plantar warts: a double blind study.", "content": "Ultrasound and plantar warts: a double blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206165"} {"pmid": "4206166", "title": "Lobo's disease involving the skin of a dolphin.", "content": "Lobo's disease involving the skin of a dolphin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206166"} {"pmid": "4206167", "title": "Bradycardia tachycardia syndrome in a patient with a mitral prosthesis: case report.", "content": "Bradycardia tachycardia syndrome in a patient with a mitral prosthesis: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206167"} {"pmid": "4206168", "title": "Arteriovenous malformations in Koreans.", "content": "Arteriovenous malformations in Koreans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206168"} {"pmid": "4206169", "title": "Alcoholism clinic in a military setting: a combined disulfiram and group therapy outpatient program.", "content": "Alcoholism clinic in a military setting: a combined disulfiram and group therapy outpatient program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206169"} {"pmid": "4206171", "title": "Isolated Crohn's disease of the appendix: case report.", "content": "Isolated Crohn's disease of the appendix: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206171"} {"pmid": "4206170", "title": "Parenteral hyperalimentation for severe postvagotomy gastric stasis: case report.", "content": "Parenteral hyperalimentation for severe postvagotomy gastric stasis: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206170"} {"pmid": "4206173", "title": "Editorial: The hip osteotomy in orthopaedic surgery.", "content": "Editorial: The hip osteotomy in orthopaedic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206173"} {"pmid": "4206172", "title": "One stage diagnosis and treatment of intrathoracic disease.", "content": "One stage diagnosis and treatment of intrathoracic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206172"} {"pmid": "4206174", "title": "Dosage compensation of sex-linked genes in Drosophila melanogaster. The activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in flies with normal and disturbed genetic balance.", "content": "Dosage compensation of sex-linked genes in Drosophila melanogaster. The activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in flies with normal and disturbed genetic balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206174"} {"pmid": "4206175", "title": "Content of RNA polymerase in haploid and merodiploid strains of Escherichia coli.", "content": "Content of RNA polymerase in haploid and merodiploid strains of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206175"} {"pmid": "4206178", "title": "The diagnosis of bovine mastitis: a critical evaluation of a polyvalent radial immunodiffusion test and other methods.", "content": "The diagnosis of bovine mastitis: a critical evaluation of a polyvalent radial immunodiffusion test and other methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206178"} {"pmid": "4206179", "title": "Locomotor body equilibrium after diazepam injection in the squirrel monkey.", "content": "Locomotor body equilibrium after diazepam injection in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206179"} {"pmid": "4206180", "title": "Combined radiotherapy and chemotherapy in the treatment of Hodgkin's disease.", "content": "Combined radiotherapy and chemotherapy in the treatment of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206180"} {"pmid": "4206181", "title": "Use of serial exercise tests to assess the efficacy and duration of action of drugs for asthma.", "content": "Use of serial exercise tests to assess the efficacy and duration of action of drugs for asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206181"} {"pmid": "4206183", "title": "Metabolism of synthetic steroids by animals and man.", "content": "Metabolism of synthetic steroids by animals and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206183"} {"pmid": "4206184", "title": "Teratogenic screening methods and their application to contraceptive products.", "content": "Teratogenic screening methods and their application to contraceptive products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206184"} {"pmid": "4206185", "title": "U.S. Food and Drug Administration requirements for toxicity testing of contraceptive products.", "content": "U.S. Food and Drug Administration requirements for toxicity testing of contraceptive products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206185"} {"pmid": "4206187", "title": "Special requirements for plastic devices.", "content": "Special requirements for plastic devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206187"} {"pmid": "4206186", "title": "Design of early clinical trials for new contraceptive methods.", "content": "Design of early clinical trials for new contraceptive methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206186"} {"pmid": "4206188", "title": "Special problems in toxicity testing of long acting depot contraceptives.", "content": "Special problems in toxicity testing of long acting depot contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206188"} {"pmid": "4206189", "title": "Special requirements for testing post-coital contraceptives.", "content": "Special requirements for testing post-coital contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206189"} {"pmid": "4206190", "title": "Special requirements for testing spermicides.", "content": "Special requirements for testing spermicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206190"} {"pmid": "4206191", "title": "Special requirements for toxicity testing of oral compounds administered continuously or cyclically.", "content": "Special requirements for toxicity testing of oral compounds administered continuously or cyclically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206191"} {"pmid": "4206192", "title": "Special requirements for toxicological testing of metal-releasing intrauterine devices.", "content": "Special requirements for toxicological testing of metal-releasing intrauterine devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206192"} {"pmid": "4206193", "title": "Special toxicology for the prostaglandins.", "content": "Special toxicology for the prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206193"} {"pmid": "4206194", "title": "Absorption and elimination of polychlorinated biphenyls (PCB) in goldfish.", "content": "Absorption and elimination of polychlorinated biphenyls (PCB) in goldfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206194"} {"pmid": "4206195", "title": "Regional variation in the presence of mast cells in the mammalian brain.", "content": "Regional variation in the presence of mast cells in the mammalian brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206195"} {"pmid": "4206196", "title": "On the phenomenon of the two linear Hammett relationships: its origin and its use as a tool in the analysis of diamine oxidase preparations.", "content": "On the phenomenon of the two linear Hammett relationships: its origin and its use as a tool in the analysis of diamine oxidase preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206196"} {"pmid": "4206197", "title": "Muscular subaortic stenosis and Friedreich's ataxia.", "content": "Muscular subaortic stenosis and Friedreich's ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206197"} {"pmid": "4206198", "title": "Placental CO2 transfer after fetal carbonic anhydrase inhibition.", "content": "Placental CO2 transfer after fetal carbonic anhydrase inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206198"} {"pmid": "4206201", "title": "Immunological identification of nascent subunits of wheat ribulose diphosphate carboxylase on ribosomes of both chloroplast and cytoplasmic origin.", "content": "Immunological identification of nascent subunits of wheat ribulose diphosphate carboxylase on ribosomes of both chloroplast and cytoplasmic origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206201"} {"pmid": "4206202", "title": "Hyaluronidase and esterase activities of the venom of the poisonous brown recluse spider.", "content": "Hyaluronidase and esterase activities of the venom of the poisonous brown recluse spider.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206202"} {"pmid": "4206203", "title": "A rat liver protein with potential thrombin activity: properties and partial purification.", "content": "A rat liver protein with potential thrombin activity: properties and partial purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206203"} {"pmid": "4206206", "title": "Mechanocardiography and hemodynamics.", "content": "Mechanocardiography and hemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206206"} {"pmid": "4206199", "title": "The similarities of optokinetic after-nystagmus to the vestibular nystagmus.", "content": "The similarities of optokinetic after-nystagmus to the vestibular nystagmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206199"} {"pmid": "4206200", "title": "Quantitative determination of secretory immunoglobulin A (SIgA) in middle ear effusions.", "content": "Quantitative determination of secretory immunoglobulin A (SIgA) in middle ear effusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206200"} {"pmid": "4206204", "title": "Physiological correlates of auditory stimulus periodicity.", "content": "Physiological correlates of auditory stimulus periodicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206204"} {"pmid": "4206205", "title": "Structural and physiological features of the organ of Corti.", "content": "Structural and physiological features of the organ of Corti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206205"} {"pmid": "4206209", "title": "Facilitation of Fe(II) autoxidation by Fe(3) complexing agents.", "content": "Facilitation of Fe(II) autoxidation by Fe(3) complexing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206209"} {"pmid": "4206208", "title": "Early diagnosis of arterial atherosclerosis by means of resonance electrosphygmography.", "content": "Early diagnosis of arterial atherosclerosis by means of resonance electrosphygmography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206208"} {"pmid": "4206207", "title": "Hemodynamic stress and relief of the heart in the light of comparative physiological investigations.", "content": "Hemodynamic stress and relief of the heart in the light of comparative physiological investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206207"} {"pmid": "4206210", "title": "The storage and manipulation of radiation dose data in a small digital computer.", "content": "The storage and manipulation of radiation dose data in a small digital computer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206210"} {"pmid": "4206211", "title": "Letter: A rapid method for the determination of tumour RBE.", "content": "Letter: A rapid method for the determination of tumour RBE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206211"} {"pmid": "4206213", "title": "Ossifying lipoma.", "content": "Ossifying lipoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206213"} {"pmid": "4206220", "title": "Hypersensitivtiy responses in monkeys. VI. P-K, histamine, 48-80 responses after challenges with heterologous antigen or the other agents.", "content": "Hypersensitivtiy responses in monkeys. VI. P-K, histamine, 48-80 responses after challenges with heterologous antigen or the other agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206220"} {"pmid": "4206212", "title": "Dwarfism in the newborn: the nomenclature, radiological features and genetic significance.", "content": "Dwarfism in the newborn: the nomenclature, radiological features and genetic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206212"} {"pmid": "4206218", "title": "Uptake of disodium cromoglycate in obstructive airways disease.", "content": "Uptake of disodium cromoglycate in obstructive airways disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206218"} {"pmid": "4206217", "title": "Allergy to snake venom: the use of radioimmunoassay for the detection of IgE antibodies against antigens not suitable for cutaneous tests.", "content": "Allergy to snake venom: the use of radioimmunoassay for the detection of IgE antibodies against antigens not suitable for cutaneous tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206217"} {"pmid": "4206214", "title": "Penicillin treatment of gonorrhoea in Edinburgh.", "content": "Penicillin treatment of gonorrhoea in Edinburgh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206214"} {"pmid": "4206219", "title": "The effect of frequent administration of sodium cromoglycate to asthmatic children who previously responded poorly.", "content": "The effect of frequent administration of sodium cromoglycate to asthmatic children who previously responded poorly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206219"} {"pmid": "4206215", "title": "Absence of chlorinated dibenzodioxins and dibenzofurans from aquatic animals.", "content": "Absence of chlorinated dibenzodioxins and dibenzofurans from aquatic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206215"} {"pmid": "4206216", "title": "Polychlorinated biphenyls (PCB) in sea water and their effect on reproduction of Gammarus oceanicus.", "content": "Polychlorinated biphenyls (PCB) in sea water and their effect on reproduction of Gammarus oceanicus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206216"} {"pmid": "4206240", "title": "An overview of the mycotoxicoses of domestic animals.", "content": "An overview of the mycotoxicoses of domestic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206240"} {"pmid": "4206242", "title": "Proceedings: Serum amylase and related enzymes in diabetic ketoacidosis.", "content": "Proceedings: Serum amylase and related enzymes in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206242"} {"pmid": "4206241", "title": "Superiority of simplified assay for folate with Lactobacillus casei ATCC 7469 over assay with chloramphenicol-adapted strain.", "content": "Superiority of simplified assay for folate with Lactobacillus casei ATCC 7469 over assay with chloramphenicol-adapted strain. Direct assay of serum folate by mixing serum with a mixture of L. casei and medium without autoclaving was found to provide serum folate results similar to those by extraction of serum with heat. This procedure was found more reliable than that using the same technique with chloramphenicol and a strain of L. casei adapted to grow in this material. A portion of apparent folate activity assayed in haemolysates by such direct assay was found to be due to material other than folate. It is recommended that heat extraction of haemolysates be continued for determination of whole blood folate, or that an additional standardization of technique be included if direct assay is used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206241"} {"pmid": "4206243", "title": "Echocardiographic M-scan technique in the diagnosis of pericardial effusion.", "content": "Echocardiographic M-scan technique in the diagnosis of pericardial effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206243"} {"pmid": "4206244", "title": "DEAE-cellulose chromatography: a method for dissociation of soluble immune complexes of hepatitis B antigen.", "content": "DEAE-cellulose chromatography: a method for dissociation of soluble immune complexes of hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206244"} {"pmid": "4206245", "title": "Reaction mechanisms of nascent C567 (reactive lysis). II. Killing of a rough form of Escherichia coli by C567, C8, and C9.", "content": "Reaction mechanisms of nascent C567 (reactive lysis). II. Killing of a rough form of Escherichia coli by C567, C8, and C9.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206245"} {"pmid": "4206246", "title": "An immunologic model in laboratory animals for the study of Neisseria gonorrhoeae.", "content": "An immunologic model in laboratory animals for the study of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206246"} {"pmid": "4206247", "title": "Characterization of brain-associated rabies neutralizing substance.", "content": "Characterization of brain-associated rabies neutralizing substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206247"} {"pmid": "4206248", "title": "Pharmacokinetics of ampicillin in the newborn infant.", "content": "Pharmacokinetics of ampicillin in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206248"} {"pmid": "4206249", "title": "Protective effect of pyocin against lethal Pseudomonas aeruginosa infections in mice.", "content": "Protective effect of pyocin against lethal Pseudomonas aeruginosa infections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206249"} {"pmid": "4206250", "title": "The effect of chemotherapy for tuberculosis on immunity to tuberculosis.", "content": "The effect of chemotherapy for tuberculosis on immunity to tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206250"} {"pmid": "4206254", "title": "On the control of cholesterol synthesis.", "content": "On the control of cholesterol synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206254"} {"pmid": "4206255", "title": "Management of stable angina.", "content": "Management of stable angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206255"} {"pmid": "4206256", "title": "Microbes. 4. Robert Koch: anthrax bacilli isolated.", "content": "Microbes. 4. Robert Koch: anthrax bacilli isolated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206256"} {"pmid": "4206257", "title": "Studies in head injury. I. An experimental model of closed head injury.", "content": "Studies in head injury. I. An experimental model of closed head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206257"} {"pmid": "4206258", "title": "Studies in head injury. II. Effect of dexamethasone on traumatic brain swelling.", "content": "Studies in head injury. II. Effect of dexamethasone on traumatic brain swelling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206258"} {"pmid": "4206264", "title": "RNA synthesis in the uterine epithelium stimulated by estrogen injection.", "content": "RNA synthesis in the uterine epithelium stimulated by estrogen injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206264"} {"pmid": "4206263", "title": "The synthesis of fat and water soluble arseno organic compounds in marine and limnetic algae.", "content": "The synthesis of fat and water soluble arseno organic compounds in marine and limnetic algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206263"} {"pmid": "4206268", "title": "Uptake and hydrolysis of 131-I-albumin in the toad liver. The effect of low body temperature.", "content": "Uptake and hydrolysis of 131-I-albumin in the toad liver. The effect of low body temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206268"} {"pmid": "4206269", "title": "Cultivation of animal cells in chemically defined media, a review.", "content": "Cultivation of animal cells in chemically defined media, a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206269"} {"pmid": "4206270", "title": "Isoelectric fractionation of sulfated glycoproteins on polytetrafluoroethylene-coated columns.", "content": "Isoelectric fractionation of sulfated glycoproteins on polytetrafluoroethylene-coated columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206270"} {"pmid": "4206271", "title": "Specific tlc, gc, and gc-ms methods for kinetic studies with COMT.", "content": "Specific tlc, gc, and gc-ms methods for kinetic studies with COMT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206271"} {"pmid": "4206273", "title": "Flexibacteria.", "content": "Flexibacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206273"} {"pmid": "4206272", "title": "Differentiation of DNA and RNA on filter paper discs.", "content": "Differentiation of DNA and RNA on filter paper discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206272"} {"pmid": "4206274", "title": "Amidase activity of human alpha-macroglobulin.", "content": "Amidase activity of human alpha-macroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206274"} {"pmid": "4206275", "title": "Inhibition of growth of transplantable melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse) by chlorpromazine.", "content": "Inhibition of growth of transplantable melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse) by chlorpromazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206275"} {"pmid": "4206276", "title": "Inhibiting effect of chloroquine diphosphate on the growth of tumors and activity of some acid hydrolases of a melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse).", "content": "Inhibiting effect of chloroquine diphosphate on the growth of tumors and activity of some acid hydrolases of a melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206276"} {"pmid": "4206278", "title": "A new case of IgD-myeloma associated with hypogammaglobulinemia.", "content": "A new case of IgD-myeloma associated with hypogammaglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206278"} {"pmid": "4206284", "title": "Evaluation of lidoflazine as an anti-anginal drug.", "content": "Evaluation of lidoflazine as an anti-anginal drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206284"} {"pmid": "4206285", "title": "Reaching in light and dark after unilateral posterior parietal ablations in the monkey.", "content": "Reaching in light and dark after unilateral posterior parietal ablations in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206285"} {"pmid": "4206286", "title": "An international survey on nutrition and pancreatitis.", "content": "An international survey on nutrition and pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206286"} {"pmid": "4206287", "title": "Developmental studies on some enzymes associated with 'detoxication'.", "content": "Developmental studies on some enzymes associated with 'detoxication'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206287"} {"pmid": "4206290", "title": "Careful presentation of evidence helps clear hospital.", "content": "Careful presentation of evidence helps clear hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206290"} {"pmid": "4206291", "title": "The CHSLP financial model.", "content": "The CHSLP financial model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206291"} {"pmid": "4206292", "title": "The use of a whole body counter for measuring bone marrow erythroid activity by profile scanning.", "content": "The use of a whole body counter for measuring bone marrow erythroid activity by profile scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206292"} {"pmid": "4206293", "title": "Recent advances in whole-body counting: a review.", "content": "Recent advances in whole-body counting: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206293"} {"pmid": "4206295", "title": "Effects of microsporidan infection on larval trematodes: infection with Nosema strigeoideae or N. echinostomi.", "content": "Effects of microsporidan infection on larval trematodes: infection with Nosema strigeoideae or N. echinostomi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206295"} {"pmid": "4206296", "title": "The etiological agent of cytoplasmic incompatibility in Culex pipiens.", "content": "The etiological agent of cytoplasmic incompatibility in Culex pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206296"} {"pmid": "4206297", "title": "The infection of nonmosquito hosts by injection with spores of the microsporidan Nosema algerae.", "content": "The infection of nonmosquito hosts by injection with spores of the microsporidan Nosema algerae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206297"} {"pmid": "4206298", "title": "High energy x-ray therapy of gastric carcinoma.", "content": "High energy x-ray therapy of gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206298"} {"pmid": "4206299", "title": "An electron microscopic study of the neurons of the primate motor and somatic sensory cortices.", "content": "An electron microscopic study of the neurons of the primate motor and somatic sensory cortices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206299"} {"pmid": "4206300", "title": "An electron microscope study of the termination of afferent connections to the primate motor cortex.", "content": "An electron microscope study of the termination of afferent connections to the primate motor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206300"} {"pmid": "4206303", "title": "Preparation and use of benzhydrylamine polymers in peptide synthesis. II. Syntheses of thyrotropin releasing hormone, thyrocalcitonin 26-32, and eledoisin.", "content": "Preparation and use of benzhydrylamine polymers in peptide synthesis. II. Syntheses of thyrotropin releasing hormone, thyrocalcitonin 26-32, and eledoisin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206303"} {"pmid": "4206304", "title": "The importance of routine urine culture in malnourished children.", "content": "The importance of routine urine culture in malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206304"} {"pmid": "4206305", "title": "Nutritional problems of children in new urban families.", "content": "Nutritional problems of children in new urban families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206305"} {"pmid": "4206307", "title": "Adrenal regulation of protein synthesis in protein malnutrition.", "content": "Adrenal regulation of protein synthesis in protein malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206307"} {"pmid": "4206306", "title": "Pediatric surgery. 1.", "content": "Pediatric surgery. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206306"} {"pmid": "4206301", "title": "Advantages and limitations of radioisotope clearance methods from a clinician's point of view.", "content": "Advantages and limitations of radioisotope clearance methods from a clinician's point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206301"} {"pmid": "4206302", "title": "Renal clearance investigation with radionuclides.", "content": "Renal clearance investigation with radionuclides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206302"} {"pmid": "4206317", "title": "Aphakia and multiple ocular defects in Saint Bernard puppies.", "content": "Aphakia and multiple ocular defects in Saint Bernard puppies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206317"} {"pmid": "4206320", "title": "Content of beta-2-microglobulin and albumin in human amniotic fluid. A study of normal pregnancies and pregnancies complicated by haemolytic disease.", "content": "Content of beta-2-microglobulin and albumin in human amniotic fluid. A study of normal pregnancies and pregnancies complicated by haemolytic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206320"} {"pmid": "4206310", "title": "Present day management and treatment of Hodgkin's disease.", "content": "Present day management and treatment of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206310"} {"pmid": "4206321", "title": "Isolation and identification of Corynebacterium vaginale (Haemophilus vaginalis) in women with infections of the lower genital tract.", "content": "Isolation and identification of Corynebacterium vaginale (Haemophilus vaginalis) in women with infections of the lower genital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206321"} {"pmid": "4206322", "title": "Effect of oral contraceptives on the plasma concentration of pyridoxal phosphate.", "content": "Effect of oral contraceptives on the plasma concentration of pyridoxal phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206322"} {"pmid": "4206325", "title": "Multiple fetal and adult hemoglobins in Malaysian Macaca nemestrina: consequences of a-chain variation.", "content": "Multiple fetal and adult hemoglobins in Malaysian Macaca nemestrina: consequences of a-chain variation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206325"} {"pmid": "4206326", "title": "Amino acid compositions of the tryptic peptides comprising the beta-hemoglobin chain of Macaca nemestrina.", "content": "Amino acid compositions of the tryptic peptides comprising the beta-hemoglobin chain of Macaca nemestrina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206326"} {"pmid": "4206324", "title": "Intestinal absorption of D-xylose and folic acid in protein-deficient patas monkeys (Erythrocebus patas).", "content": "Intestinal absorption of D-xylose and folic acid in protein-deficient patas monkeys (Erythrocebus patas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206324"} {"pmid": "4206328", "title": "Sharing of Cercarienhüllen Reaktion antigens between Schistosoma mansoni cercariae and adults and uninfected Biomphalaria pfeifferi.", "content": "Sharing of Cercarienhüllen Reaktion antigens between Schistosoma mansoni cercariae and adults and uninfected Biomphalaria pfeifferi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206328"} {"pmid": "4206329", "title": "Ecology of viruses isolated from Panamanian phlebotomine sandflies.", "content": "Ecology of viruses isolated from Panamanian phlebotomine sandflies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206329"} {"pmid": "4206330", "title": "Childhood pigeon breeder's disease.", "content": "Childhood pigeon breeder's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206330"} {"pmid": "4206331", "title": "Simian gastropathy with submucosal glands and cysts. Gastritis glandularis or cystica profunda?", "content": "Simian gastropathy with submucosal glands and cysts. Gastritis glandularis or cystica profunda?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206331"} {"pmid": "4206323", "title": "Isolation of Candida species from the gastrointestinal tract in malnourished children.", "content": "Isolation of Candida species from the gastrointestinal tract in malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206323"} {"pmid": "4206327", "title": "Behavior of an all-juvenile group of Rhesus monkeys.", "content": "Behavior of an all-juvenile group of Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206327"} {"pmid": "4206334", "title": "Effects of nitroglycerin on left ventricular wall motion in coronary artery disease.", "content": "Effects of nitroglycerin on left ventricular wall motion in coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206334"} {"pmid": "4206335", "title": "The analysis of the effects of early experiences.", "content": "The analysis of the effects of early experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206335"} {"pmid": "4206336", "title": "Dynamics of spermiogenesis in Drosophila melanogaster. 3. Relation between axoneme and mitochondrial derivatives.", "content": "Dynamics of spermiogenesis in Drosophila melanogaster. 3. Relation between axoneme and mitochondrial derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206336"} {"pmid": "4206337", "title": "Comparative growth characteristics of VERO cells on gas-permeable and conventional supports.", "content": "Comparative growth characteristics of VERO cells on gas-permeable and conventional supports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206337"} {"pmid": "4206338", "title": "DNA synthesis following refeeding of starved Tetrahymena pyriformis GL: starved cells are arrested in G 1.", "content": "DNA synthesis following refeeding of starved Tetrahymena pyriformis GL: starved cells are arrested in G 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206338"} {"pmid": "4206339", "title": "A convenient method for enucleating cells in quantity.", "content": "A convenient method for enucleating cells in quantity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206339"} {"pmid": "4206340", "title": "Perivascular hemorrhagic lesions in temporal cortex following cerebral infarction (a morphological study).", "content": "Perivascular hemorrhagic lesions in temporal cortex following cerebral infarction (a morphological study).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206340"} {"pmid": "4206341", "title": "The chemical composition and ultrastructure of the cell wall of Scenedesmus obliquus. II. Amino acids, proteins and antigens.", "content": "The chemical composition and ultrastructure of the cell wall of Scenedesmus obliquus. II. Amino acids, proteins and antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206341"} {"pmid": "4206342", "title": "Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid.", "content": "Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid. The in vitro binding properties of enterotoxins of Vibrio cholerae and Escherichia coli to different pure gangliosides and related neutral glycosphin-golipids were analyzed with a sorbent assay utilizing plastic tubes to which the glycolipid substances had been coupled. It was found that the cholera toxin bound to G(M1) ganglioside better than to the other tested substances G(M3), G(M3)-NGN, G(M2), G(D1a), G(D1b), G(T), G(A1), tetrahexoside-GlcNac and globoside. With this assay using G(M1)-coated tubes it is possible to measure cholera toxin even at concentrations below 1 ng/ml. Also enterotoxin of various E. coli strains bound to G(M1), but the affinity was much less than for cholera toxin. The G(M1) ganglioside, in contrast to the other glycosphingolipids, effectively inactivated cholera toxin as determined with the intradermal and the ileal loop assays; approximately equimolar concentrations of the ganglioside in relation to toxin sufficed. Also, the skin and ileal loop activities of E. coli enterotoxins could be inhibited by G(M1); however, several orders more of the ganglioside were required for such inhibition than for inactivation of the cholera toxin, and the differences between G(M1) and the other substances were less pronounced for E. coli toxins. Preincubation of rabbit ileal loops with choleragenoid, a natural toxoid of V. cholerae which has binding properties to the G(M1) ganglioside similar to cholera toxin, made the loops resistant to subsequently added enterotoxin of V. cholerae. The responsiveness to enterotoxin of E. coli was not reduced by this toxoid. A likely interpretation of these data is that the G(M1) ganglioside constitutes or at least contains the structure of functional tissue receptors for the cholera toxin, whereas the weak binding to G(M1) by E. coli enterotoxins is probably a pathogenetically insignificant reflection of structural similarities between these toxins and cholera toxin. Consequently, the cholera toxoid by occupying functional intestinal G(M1) receptors for the cholera toxin could inhibit the ileal response to this toxin, but not the response to E. coli enterotoxin since the intestinal receptors for the latter toxin are not affected by the cholera toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206342"} {"pmid": "4206343", "title": "Pathogenicity and immunogenic efficacy of a live attentuated plaque vaccine in vervet monkeys.", "content": "Pathogenicity and immunogenic efficacy of a live attentuated plaque vaccine in vervet monkeys. A live attenuated Yersinia pestis (Pasteurella pestis) vaccine strain designated EV51f, which had been passaged through guinea pigs previously treated with ferrous sulfate, was shown to be pathogenic for African green vervet monkeys (Cercopithecus aethips pygerythrus), but not for guinea pigs. The bacilli multiplied in the monkeys, as shown by positive blood cultures, caused an elevation of white cell counts and rectal temperatures, and resulted in death of 26% (13/50) of animals. Postmortem findings of these animals were typical of bubonic-septicemic plague. This vaccine did not cause deaths in 50 guinea pigs even in doses up to 100 million viable bacilli inoculated subcutaneously. It is suggested that the virulence of an attenuated Y. pestis strain which does not produce pigment on a defined medium containing hemin, but possesses all other known virulence determinants, is dependent on the availability of iron in vivo. The serological response of the monkeys as determined by the hemagglutinating and mouse protective antibodies was high one month after vaccination and also in guinea pigs, as shown by virulent challenge. This antibody level declined in monkeys over a period of nearly 6 months, and a decline in immunity was confirmed by virulent challenge which resulted in the death of 30% of vaccinated monkeys. The level of immunity in monkeys did not appear to be related to the dose of vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206343"} {"pmid": "4206346", "title": "Contact sensitivity in vitro: activation of actively allergized lymphocytes by a beryllium complex.", "content": "Contact sensitivity in vitro: activation of actively allergized lymphocytes by a beryllium complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206346"} {"pmid": "4206345", "title": "Pathogenesis and immunology of experimental gonococcal infection: virulence of colony types of Neisseria gonorrhoeae for chicken embryos.", "content": "Pathogenesis and immunology of experimental gonococcal infection: virulence of colony types of Neisseria gonorrhoeae for chicken embryos. The virulence of gonococcal strains and colony types was evaluated in embryonated hen eggs of various ages inoculated by different routes. Striking differences in virulence of colony types were revealed by intravenous inoculation of 11-day embryos. T1 and T2 colony types were found to have high virulence for embryos, whereas T3 and T4 colony types were relatively avirulent. These observations are in accord with previous studies in volunteers. The differences in virulence were not related to differences in toxicity of killed gonococci, sonic lysates, or to the susceptibility of gonococci to cidal effects of chicken embryo blood. Rather, they appeared to involve differences in clearance of gonococci from the blood stream and subsequent multiplication of the virulent colony types. Infection with virulent colony types appears to be primarily bacteremic in this model. Preliminary experiments indicated that chicken embryos may be protected against the lethal infection by prior treatment of the inoculum with normal and immune rabbit serum. This protective effect was not associated with bactericidal activity. The chicken embryo model is potentially useful as a means of investigating attributes of virulence of gonococci and factors in immunity against gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206345"} {"pmid": "4206344", "title": "Immunological studies on the envelope component of Venezuelan equine encephalomyelitis virus.", "content": "Immunological studies on the envelope component of Venezuelan equine encephalomyelitis virus. Treatment of purified Venezuelan equine encephalomyelitis virus with the nonionic detergent Triton X-100 permitted spearation of the envelope from the core component. The isolated envelope was a noninfectious immunogen which reacted in hemagglutination, hemagglutination inhibition, complement fixation, and neutralization serological reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206344"} {"pmid": "4206347", "title": "Structure and biological functions of human IgD. 3. Phylogenetic studies of IgD.", "content": "Structure and biological functions of human IgD. 3. Phylogenetic studies of IgD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206347"} {"pmid": "4206348", "title": "Isolation of a low molecular weight ragweed pollen allergen: Ra5.", "content": "Isolation of a low molecular weight ragweed pollen allergen: Ra5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206348"} {"pmid": "4206349", "title": "A study of immunoglobulins in jejunal secretion and serum of patients suffering from Mediterranean cirrhosis.", "content": "A study of immunoglobulins in jejunal secretion and serum of patients suffering from Mediterranean cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206349"} {"pmid": "4206350", "title": "Regulation of lipogenesis and the total activities of lipogenic enzymes in a primary culture of hepatocytes from prenatal and early postnatal chicks.", "content": "Regulation of lipogenesis and the total activities of lipogenic enzymes in a primary culture of hepatocytes from prenatal and early postnatal chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206350"} {"pmid": "4206351", "title": "Purification of ribonucleic acid polymerase from SP82-infected Bacillus subtilis.", "content": "Purification of ribonucleic acid polymerase from SP82-infected Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206351"} {"pmid": "4206352", "title": "In vivo and in vitro transcription by ribonucleic acid polymerase from SP82-infected Bacillus subtilis.", "content": "In vivo and in vitro transcription by ribonucleic acid polymerase from SP82-infected Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206352"} {"pmid": "4206353", "title": "Recognition of primary sequence variations among sperm whale myoglobin components with successive proteolysis procedures.", "content": "Recognition of primary sequence variations among sperm whale myoglobin components with successive proteolysis procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206353"} {"pmid": "4206354", "title": "A mammalian endonuclease specific for apurinic sites in double-stranded deoxyribonucleic acid. I. Purification and general properties.", "content": "A mammalian endonuclease specific for apurinic sites in double-stranded deoxyribonucleic acid. I. Purification and general properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206354"} {"pmid": "4206355", "title": "Preparation and prolonged tissue retention of liposome-encapsulated chelating agents.", "content": "Preparation and prolonged tissue retention of liposome-encapsulated chelating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206355"} {"pmid": "4206358", "title": "Identification of blood meals of sandflies (Diptera: psychodidae).", "content": "Identification of blood meals of sandflies (Diptera: psychodidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206358"} {"pmid": "4206356", "title": "Three isoaccepting forms of leucyl transfer RNA in mitochondria.", "content": "Three isoaccepting forms of leucyl transfer RNA in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206356"} {"pmid": "4206357", "title": "Cerebral circulation and metabolism. Summary of International Symposium, June 6-10, 1973.", "content": "Cerebral circulation and metabolism. Summary of International Symposium, June 6-10, 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206357"} {"pmid": "4206359", "title": "Long term effects of aflatoxin B1 and viral hepatitis on marmoset liver. A preliminary report.", "content": "Long term effects of aflatoxin B1 and viral hepatitis on marmoset liver. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206359"} {"pmid": "4206360", "title": "Ultrastructural changes in the liver of baboons following lead and endotoxin administration.", "content": "Ultrastructural changes in the liver of baboons following lead and endotoxin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206360"} {"pmid": "4206361", "title": "Mechanism of denaturation of haemoglobin by alkali.", "content": "Mechanism of denaturation of haemoglobin by alkali.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206361"} {"pmid": "4206362", "title": "Intra- and interpopulation selection concerning the alcohol dehydrogenase locus in Drosophila melanogaster.", "content": "Intra- and interpopulation selection concerning the alcohol dehydrogenase locus in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206362"} {"pmid": "4206365", "title": "Therapeutic value of local perfusion for acute spinal cord trauma.", "content": "Therapeutic value of local perfusion for acute spinal cord trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206365"} {"pmid": "4206363", "title": "Nitrosocarbaryl as a potent mutagen of environmental significance.", "content": "Nitrosocarbaryl as a potent mutagen of environmental significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206363"} {"pmid": "4206366", "title": "In vivo measurement of cerebral glucose metabolism employing 11C-labeled glucose.", "content": "In vivo measurement of cerebral glucose metabolism employing 11C-labeled glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206366"} {"pmid": "4206367", "title": "Impaired tool-using behavior in monkeys from bilateral destruction of the dorsomedial nuclei of the thalamus.", "content": "Impaired tool-using behavior in monkeys from bilateral destruction of the dorsomedial nuclei of the thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206367"} {"pmid": "4206368", "title": "Clinical grade, regional cerebral blood flow, and angiographical spasm in the monkey after subarachnoid hemorrhage.", "content": "Clinical grade, regional cerebral blood flow, and angiographical spasm in the monkey after subarachnoid hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206368"} {"pmid": "4206369", "title": "The effect of chronic cerebellar stimulation upon epilepsy in man.", "content": "The effect of chronic cerebellar stimulation upon epilepsy in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206369"} {"pmid": "4206370", "title": "Magnocellular neuroendocrine cells in the monkey hypothalamus.", "content": "Magnocellular neuroendocrine cells in the monkey hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206370"} {"pmid": "4206371", "title": "The modification of L-dopa induced dyskinesias in the monkey by unilateral nigral lesions.", "content": "The modification of L-dopa induced dyskinesias in the monkey by unilateral nigral lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206371"} {"pmid": "4206372", "title": "Experimental tremor following CNS lesions in monkeys.", "content": "Experimental tremor following CNS lesions in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206372"} {"pmid": "4206373", "title": "Physiopathological study in monkeys with partial and complete destruction of cerebellar structures.", "content": "Physiopathological study in monkeys with partial and complete destruction of cerebellar structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206373"} {"pmid": "4206374", "title": "Some new observations on intracerebellar nuclei: their participation in patterned movements.", "content": "Some new observations on intracerebellar nuclei: their participation in patterned movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206374"} {"pmid": "4206375", "title": "\"Triadic\" synapses and other articulations of interneurons in the lateral geniculate nucleus of rhesus monkeys.", "content": "\"Triadic\" synapses and other articulations of interneurons in the lateral geniculate nucleus of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206375"} {"pmid": "4206376", "title": "Petit mal status presenting as psychasis.", "content": "Petit mal status presenting as psychasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206376"} {"pmid": "4206377", "title": "Cerebellopontine influence on the motor system: a functional and anatomical study following section of the brachium pontis in trained macaque monkeys.", "content": "Cerebellopontine influence on the motor system: a functional and anatomical study following section of the brachium pontis in trained macaque monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206377"} {"pmid": "4206378", "title": "Visual inhibition of nystagmus by the flocculus.", "content": "Visual inhibition of nystagmus by the flocculus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206378"} {"pmid": "4206379", "title": "Abnormal drug metabolism in rats after an inflammatory insult.", "content": "Abnormal drug metabolism in rats after an inflammatory insult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206379"} {"pmid": "4206380", "title": "The prophylactic and therapeutic effects of gold sodium thiomalate against adjuvant-induced polyarthritis in rats.", "content": "The prophylactic and therapeutic effects of gold sodium thiomalate against adjuvant-induced polyarthritis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206380"} {"pmid": "4206381", "title": "Esophageal surgery: a procedure for posterior invagination esophagogastrostomy in one-stage without positional change.", "content": "Esophageal surgery: a procedure for posterior invagination esophagogastrostomy in one-stage without positional change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206381"} {"pmid": "4206382", "title": "Surgical management of carcinoma of the maxilla.", "content": "Surgical management of carcinoma of the maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206382"} {"pmid": "4206386", "title": "Causes of death in irradiated adult insects.", "content": "Causes of death in irradiated adult insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206386"} {"pmid": "4206385", "title": "Urinary excretion in the rat of nifurpipone (NP) and of nitrofurantoin (NTF) administered by different routes.", "content": "Urinary excretion in the rat of nifurpipone (NP) and of nitrofurantoin (NTF) administered by different routes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206385"} {"pmid": "4206387", "title": "Response pattern complexity of auditory cells in the cortex of unanesthetized monkeys.", "content": "Response pattern complexity of auditory cells in the cortex of unanesthetized monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206387"} {"pmid": "4206390", "title": "The inactivation by carbenoxolone of individual human pepsinogens and pepsins.", "content": "The inactivation by carbenoxolone of individual human pepsinogens and pepsins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206390"} {"pmid": "4206391", "title": "Transfer factor--fact or fiction?", "content": "Transfer factor--fact or fiction?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206391"} {"pmid": "4206395", "title": "Restraint and anesthesia in zoo animal practice.", "content": "Restraint and anesthesia in zoo animal practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206395"} {"pmid": "4206392", "title": "GM1-gangliosidosis. I. Clinical aspects and biochemistry.", "content": "GM1-gangliosidosis. I. Clinical aspects and biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206392"} {"pmid": "4206393", "title": "Effect of diphenylhydantoin on insulin response in the oral glucose tolerance test in children and adolescents.", "content": "Effect of diphenylhydantoin on insulin response in the oral glucose tolerance test in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206393"} {"pmid": "4206394", "title": "Sorbitol in total parenteral nutrition in pediatric patients.", "content": "Sorbitol in total parenteral nutrition in pediatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206394"} {"pmid": "4206396", "title": "Pentastoma larvae in a squirrel monkey.", "content": "Pentastoma larvae in a squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206396"} {"pmid": "4206398", "title": "Persistent pupillary membranes in a rhesus monkey.", "content": "Persistent pupillary membranes in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206398"} {"pmid": "4206399", "title": "Candida albicans infections associated with antibiotic and corticosteroid therapy in spider monkeys.", "content": "Candida albicans infections associated with antibiotic and corticosteroid therapy in spider monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206399"} {"pmid": "4206397", "title": "Pulmonary pathology in stillborn nonhuman primates.", "content": "Pulmonary pathology in stillborn nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206397"} {"pmid": "4206400", "title": "Detection of isoniazid in urine and blood serum of nonhuman primates.", "content": "Detection of isoniazid in urine and blood serum of nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206400"} {"pmid": "4206401", "title": "Alpha-ketoglutaric semialdehyde dehydrogenase of Pseudomonas. Properties of the separately induced isoenzymes.", "content": "Alpha-ketoglutaric semialdehyde dehydrogenase of Pseudomonas. Properties of the separately induced isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206401"} {"pmid": "4206402", "title": "An alpha-D-galactosyl-binding lectin from Bandeiraea simplicifolia seeds. Isolation by affinity chromatography and characterization.", "content": "An alpha-D-galactosyl-binding lectin from Bandeiraea simplicifolia seeds. Isolation by affinity chromatography and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206402"} {"pmid": "4206403", "title": "Nutritional study of three strains of Naegleria gruberi.", "content": "Nutritional study of three strains of Naegleria gruberi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206403"} {"pmid": "4206404", "title": "Kudoa cerebralis sp. n. (Myxosporidea, Chloromyxidae) from the striped bass, Morone saxatilis (Walbaum).", "content": "Kudoa cerebralis sp. n. (Myxosporidea, Chloromyxidae) from the striped bass, Morone saxatilis (Walbaum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206404"} {"pmid": "4206405", "title": "Microsporidian parasites of trematode larvae from aquatic snails in West Malaysia.", "content": "Microsporidian parasites of trematode larvae from aquatic snails in West Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206405"} {"pmid": "4206406", "title": "Three avenues to ecologic research on parasitic protozoa.", "content": "Three avenues to ecologic research on parasitic protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206406"} {"pmid": "4206407", "title": "Rumen ciliate fauna of Alaskan moose (Alces americana), musk-ox (Ovibos moschatus) and Dall moutain sheep (Ovis dalli).", "content": "Rumen ciliate fauna of Alaskan moose (Alces americana), musk-ox (Ovibos moschatus) and Dall moutain sheep (Ovis dalli).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206407"} {"pmid": "4206408", "title": "Pollution.", "content": "Pollution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206408"} {"pmid": "4206409", "title": "Effects of PCB and DDE in cormorants and evaluation of PCB residues from an experimental study.", "content": "Effects of PCB and DDE in cormorants and evaluation of PCB residues from an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206409"} {"pmid": "4206410", "title": "Reproductive failure and mortality in mink fed on Great Lakes fish.", "content": "Reproductive failure and mortality in mink fed on Great Lakes fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206410"} {"pmid": "4206413", "title": "Obstruction of the common bile duct. Duodenal diverticula.", "content": "Obstruction of the common bile duct. Duodenal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206413"} {"pmid": "4206411", "title": "The role of pheromones in the social communication of marmoset monkeys (Callithricidae).", "content": "The role of pheromones in the social communication of marmoset monkeys (Callithricidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206411"} {"pmid": "4206412", "title": "On the fine structure of the acidophilic hot-spring alga Cyanidium caldarium: a taxonomic approach.", "content": "On the fine structure of the acidophilic hot-spring alga Cyanidium caldarium: a taxonomic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206412"} {"pmid": "4206426", "title": "Feto-maternal production and transfer of cortisol in the rhesus (Macaca mulatta).", "content": "Feto-maternal production and transfer of cortisol in the rhesus (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206426"} {"pmid": "4206427", "title": "Quantification of 20alpha- and 20beta-dihydroprogesterone in plasma of the pregnant rhesus monkey.", "content": "Quantification of 20alpha- and 20beta-dihydroprogesterone in plasma of the pregnant rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206427"} {"pmid": "4206429", "title": "A comparison of vocalizations of red-tailed monkeys and blue monkeys, Ceropithecus ascanius and C. mitis, in Uganda.", "content": "A comparison of vocalizations of red-tailed monkeys and blue monkeys, Ceropithecus ascanius and C. mitis, in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206429"} {"pmid": "4206442", "title": "Beneficial electrophysiologic effects of nitroglycerin during acute myocardial infarction.", "content": "Beneficial electrophysiologic effects of nitroglycerin during acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206442"} {"pmid": "4206443", "title": "Nitroglycerin-induced reduction in the incidence of spontaneous ventricular fibrillation during coronary occlusion in dogs.", "content": "Nitroglycerin-induced reduction in the incidence of spontaneous ventricular fibrillation during coronary occlusion in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206443"} {"pmid": "4206444", "title": "Ocular side-effects of oral contraceptives.", "content": "Ocular side-effects of oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206444"} {"pmid": "4206445", "title": "Minimizing systemic infection during complete parenteral alimentation of small infants.", "content": "Minimizing systemic infection during complete parenteral alimentation of small infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206445"} {"pmid": "4206432", "title": "Effects of intensity on the phototactic responses of adult anuran amphibians: a comparative survey.", "content": "Effects of intensity on the phototactic responses of adult anuran amphibians: a comparative survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206432"} {"pmid": "4206447", "title": "Electric birefringence of native DNA in an alternating field.", "content": "Electric birefringence of native DNA in an alternating field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206447"} {"pmid": "4206450", "title": "Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia.", "content": "Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206450"} {"pmid": "4206441", "title": "Rifampicin: a first line tuberculostatic drug. A critical review and appraisal.", "content": "Rifampicin: a first line tuberculostatic drug. A critical review and appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206441"} {"pmid": "4206452", "title": "Standardization of diagnostic materials. 5. Tissue culture media and reagents.", "content": "Standardization of diagnostic materials. 5. Tissue culture media and reagents. The various factors that affect the growth of cell cultures in vitro are considered and suggestions are made as to where the standardization of components would help to provide more uniform products. The manufacture of powdered media in bulk and the establishment of cell banks have been major advances, but much research is needed for the standardization or replacement of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206452"} {"pmid": "4206451", "title": "A controlled field trial of a serogroup A meningococcal polysaccharide vaccine.", "content": "A controlled field trial of a serogroup A meningococcal polysaccharide vaccine. A controlled field trial of a serogroup A meningococcal polysaccharide vaccine was conducted at three locations in Egypt during the winter cerebrospinal meningitis (CSM) season of 1971-72. The study population consisted of schoolchildren 6-15 years of age. No cases of serogroup A meningococcal CSM occurred in the group of students vaccinated with the test vaccine whereas 8 cases occurred in the control group vaccinated with tetanus toxoid, and 151 cases occurred in an unvaccinated contrast group. The case rate was significantly different between the test and control groups as well as between the test and contrast groups but was similar between the control and contrast groups. The previously demonstrated safety of the vaccine was confirmed. A significant serological response was elicited in the majority of the vaccinated students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206451"} {"pmid": "4206455", "title": "Polymer enhancement of automated immunological nephelometric analysis, as illustrated by determination of urinary albumin.", "content": "Polymer enhancement of automated immunological nephelometric analysis, as illustrated by determination of urinary albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206455"} {"pmid": "4206456", "title": "Transport of 5-methyltetrahydrofolic acid into the cerebrospinal fluid in man.", "content": "Transport of 5-methyltetrahydrofolic acid into the cerebrospinal fluid in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206456"} {"pmid": "4206458", "title": "Genetic control of quantitative variation in self-incompatibility proteins detected by immunodiffusion.", "content": "Genetic control of quantitative variation in self-incompatibility proteins detected by immunodiffusion. Single radial immunodiffusion was used to study the self-incompatibility (S) proteins present in stigmas of two inbred lines of Brassica oleracea: a self-incompatible line and a self-compatible mutant derived from it. The genetic basis of observed quantitative differences in S proteins between the two inbreds was shown to be determined by a single gene with dosage effects. Self-pollination of individual plants with high, intermediate and low levels of S protein in the stigmas, respectively, resulted in low, intermediate and high seed set.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206458"} {"pmid": "4206459", "title": "A new mutant controlling mitotic chromosome disjunction in Drosophila melanogaster.", "content": "A new mutant controlling mitotic chromosome disjunction in Drosophila melanogaster. A new mutant, mit (mitotic loss inducer), is described. The mutant is recessive and maternal in action, producing gynandromorphs and haplo-4 mosaics among the progeny of homozygous mit females. Mosaic loss of maternal or paternal chromosomes can occur. The probabilities of either maternal or paternal X chromosome loss are equal. mit has been mapped to approximately 57 on the standard X chromosome map.-Using gyandromorphs generated by mit, a morphogenetic fate map, placing the origins of 40 cuticular structures on the blastoderm surface, has been constructed. This fate map is consistent with embryological data and with the two other fate maps generated in different ways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206459"} {"pmid": "4206461", "title": "Immunogenetic aspects of nasopharyngeal carcinoma. II. Analysis of ABO, rhesus and MNSs red cell systems.", "content": "Immunogenetic aspects of nasopharyngeal carcinoma. II. Analysis of ABO, rhesus and MNSs red cell systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206461"} {"pmid": "4206463", "title": "Prospects for the prenatal diagnosis of familial hypercholesterolemia.", "content": "Prospects for the prenatal diagnosis of familial hypercholesterolemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206463"} {"pmid": "4206462", "title": "Binding of metabolites of dietary 4-dimethyl-aminoazobenzene and 2-methyl-4-dimethylamino-azobenzene to rat liver DNA and protein of subcellular fractions.", "content": "Binding of metabolites of dietary 4-dimethyl-aminoazobenzene and 2-methyl-4-dimethylamino-azobenzene to rat liver DNA and protein of subcellular fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206462"} {"pmid": "4206460", "title": "The effect of phenobarbital on cholesterol gallstones in hamsters.", "content": "The effect of phenobarbital on cholesterol gallstones in hamsters. This experimental study was undertaken to follow the influence of phenobarbital on bile chemistry and gallstone formation. Phenobarbital (400 mg/kg/day) was administered to golden hamsters receiving a diet known to induce cholesterol gallstones. After a 28-day period none of the control animals had gallstones whereas five of 12 animals with added phenobarbital developed stones. Ten of 19 animals on the lithogenic diet formed gallstones but when phenobarbital was added gallstones occurred in 16 of 19 hamsters. The administration of phenobarbital resulted in the production of bile which was relatively more saturated with cholesterol, the bile salt + phospholipid: cholesterol of 24.8 +/- 12.7 in control animals altering to 9.1 +/- 6.2 in animals receiving phenobarbital. Hepatic bilirubin uridine diphosphate-glucuronyl transferase activity was not increased in animals on phenobarbital. It was concluded that, in the hamster at least, there is no indication that large doses of phenobarbital will reduce the potential for gallstone formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206460"} {"pmid": "4206464", "title": "Low dosage anti-D immunoglobulin in the prevention of rhesus isoimmunization.", "content": "Low dosage anti-D immunoglobulin in the prevention of rhesus isoimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206464"} {"pmid": "4206465", "title": "Periodontal traumatism produced by sustained increase in occlusal vertical dimension: a histopathological study.", "content": "Periodontal traumatism produced by sustained increase in occlusal vertical dimension: a histopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206465"} {"pmid": "4206466", "title": "Demonstration by placebo response in asthma by means of exercise testing.", "content": "Demonstration by placebo response in asthma by means of exercise testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206466"} {"pmid": "4206468", "title": "Positive Foley catheter tip cultures--fact or fancy?", "content": "Positive Foley catheter tip cultures--fact or fancy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206468"} {"pmid": "4206467", "title": "Isolation of human and porcine islets of Langerhans and islet transplantation in pigs.", "content": "Isolation of human and porcine islets of Langerhans and islet transplantation in pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206467"} {"pmid": "4206469", "title": "Editorial: Prostaglandins--tour d'horizon.", "content": "Editorial: Prostaglandins--tour d'horizon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206469"} {"pmid": "4206470", "title": "Analysis of selected characteristics of a matched sample of nonprofit and proprietary nursing homes in the state of Washington.", "content": "Analysis of selected characteristics of a matched sample of nonprofit and proprietary nursing homes in the state of Washington.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206470"} {"pmid": "4206474", "title": "Evolution in action.", "content": "Evolution in action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206474"} {"pmid": "4206475", "title": "Reduction in brain dopamine following experimental cerebral ischaemia.", "content": "Reduction in brain dopamine following experimental cerebral ischaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206475"} {"pmid": "4206477", "title": "Vaccination of rhesus monkeys against malaria by use of sucrose density gradient fractions of Plasmodium knowlesi antigens.", "content": "Vaccination of rhesus monkeys against malaria by use of sucrose density gradient fractions of Plasmodium knowlesi antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206477"} {"pmid": "4206476", "title": "Blue-green bacteria synthesise L-tyrosine by the pretyrosine pathway.", "content": "Blue-green bacteria synthesise L-tyrosine by the pretyrosine pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206476"} {"pmid": "4206478", "title": "Vitamin B12 antagonism by monocarboxylic acids and anilides of cyanocobalamin.", "content": "Vitamin B12 antagonism by monocarboxylic acids and anilides of cyanocobalamin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206478"} {"pmid": "4206479", "title": "Human thyroxine-binding globulin (TBG) solid phase radioassay.", "content": "Human thyroxine-binding globulin (TBG) solid phase radioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206479"} {"pmid": "4206480", "title": "Circulating antibodies and leucocyte migration inhibition to colon-associated antigen in ulcerative colitis and Crohn's disease.", "content": "Circulating antibodies and leucocyte migration inhibition to colon-associated antigen in ulcerative colitis and Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206480"} {"pmid": "4206481", "title": "Tuberculosis in a domesticated Asiatic elephant Elephas maximus.", "content": "Tuberculosis in a domesticated Asiatic elephant Elephas maximus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206481"} {"pmid": "4206472", "title": "Bacterial colonial microstructure.", "content": "Bacterial colonial microstructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206472"} {"pmid": "4206473", "title": "Effect of esters of p-hydroxybenzoic acid on spheroplasts of Serratia marcescens and protoplasts of Bacillus megaterium.", "content": "Effect of esters of p-hydroxybenzoic acid on spheroplasts of Serratia marcescens and protoplasts of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206473"} {"pmid": "4206471", "title": "Ferulic acid as the inductor of messenger RNA synthesis related to laccase formation in the wood rotting fungus Pleurotus ostreatus.", "content": "Ferulic acid as the inductor of messenger RNA synthesis related to laccase formation in the wood rotting fungus Pleurotus ostreatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206471"} {"pmid": "4206484", "title": "Miliary tuberculosis.", "content": "Miliary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206484"} {"pmid": "4206485", "title": "Aspergillus species endocarditis. The new face of a not so rare disease.", "content": "Aspergillus species endocarditis. The new face of a not so rare disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206485"} {"pmid": "4206487", "title": "Methods to determine CO2 levels in a gonococcal transport system (Transgrow).", "content": "Methods to determine CO2 levels in a gonococcal transport system (Transgrow).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206487"} {"pmid": "4206488", "title": "The post-mortem microbiological analysis as an indicator of nosocomially-significant microorganisms in the hospital environment.", "content": "The post-mortem microbiological analysis as an indicator of nosocomially-significant microorganisms in the hospital environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206488"} {"pmid": "4206489", "title": "A five-year inhalation study with natural uranium dioxide (UO2) dust. II. Postexposure retention and biologic effects in the monkey, dog and rat.", "content": "A five-year inhalation study with natural uranium dioxide (UO2) dust. II. Postexposure retention and biologic effects in the monkey, dog and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206489"} {"pmid": "4206490", "title": "Childhood acromegaly: successful therapy with conventional radiation and effects of chlorpromazine on growth hormone and prolactin secretion.", "content": "Childhood acromegaly: successful therapy with conventional radiation and effects of chlorpromazine on growth hormone and prolactin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206490"} {"pmid": "4206491", "title": "Transport of thyroid hormones in serum and cerebrospinal fluid.", "content": "Transport of thyroid hormones in serum and cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206491"} {"pmid": "4206492", "title": "Thyrotropin and thyroidal responses to consecutive doses of thyrotropin-releasing hormone.", "content": "Thyrotropin and thyroidal responses to consecutive doses of thyrotropin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206492"} {"pmid": "4206493", "title": "Growth hormone, thyrotropin, and prolactin responses to thyrotropin-releasing hormone following diethylstilbestrol pretreatment.", "content": "Growth hormone, thyrotropin, and prolactin responses to thyrotropin-releasing hormone following diethylstilbestrol pretreatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206493"} {"pmid": "4206494", "title": "Immunogenicity and partial purification of soluble H-2 antigens extracted with hypertonic salt.", "content": "Immunogenicity and partial purification of soluble H-2 antigens extracted with hypertonic salt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206494"} {"pmid": "4206495", "title": "Specific binding of mouse IgE with rat mast cells.", "content": "Specific binding of mouse IgE with rat mast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206495"} {"pmid": "4206496", "title": "Effect of anti-mu-specific immunosuppression on Friend virus leukemia.", "content": "Effect of anti-mu-specific immunosuppression on Friend virus leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206496"} {"pmid": "4206497", "title": "Participation of different cell populations in antigen- and mitogen-induced lymphocyte proliferation. Evidence that blastogenic factor-sensitive lymphocytes are inactivated by 5-bromo-2'-deoxyuridine.", "content": "Participation of different cell populations in antigen- and mitogen-induced lymphocyte proliferation. Evidence that blastogenic factor-sensitive lymphocytes are inactivated by 5-bromo-2'-deoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206497"} {"pmid": "4206498", "title": "Aggregation of Fc'mu subfragments produced by tryptic hydrolysis of human IgM at elevated temperature.", "content": "Aggregation of Fc'mu subfragments produced by tryptic hydrolysis of human IgM at elevated temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206498"} {"pmid": "4206499", "title": "Forssman-containing liposomes: complement-dependent damage due to interaction with a monoclonal IgM.", "content": "Forssman-containing liposomes: complement-dependent damage due to interaction with a monoclonal IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206499"} {"pmid": "4206500", "title": "Skin glands as organs of communication in mammals.", "content": "Skin glands as organs of communication in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206500"} {"pmid": "4206501", "title": "Comparative chemistry of sebum.", "content": "Comparative chemistry of sebum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206501"} {"pmid": "4206502", "title": "Letter: Electron microscopic visualization of the folded chromosome of Escherichia coli.", "content": "Letter: Electron microscopic visualization of the folded chromosome of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206502"} {"pmid": "4206503", "title": "Letter: Crystallography of Bacillus subtilis levansucrase.", "content": "Letter: Crystallography of Bacillus subtilis levansucrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206503"} {"pmid": "4206504", "title": "Synthesis and turnover of Euglena gracilis mitochondrial DNA.", "content": "Synthesis and turnover of Euglena gracilis mitochondrial DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206504"} {"pmid": "4206505", "title": "Proceedings: Role of cerebellum in prism adaptation.", "content": "Proceedings: Role of cerebellum in prism adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206505"} {"pmid": "4206506", "title": "Acid protease activity in Plasmodium falciparum and P. knowlesi and ghosts of their respective host red cells.", "content": "Acid protease activity in Plasmodium falciparum and P. knowlesi and ghosts of their respective host red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206506"} {"pmid": "4206508", "title": "Part II. The spinal cord injured patient.", "content": "Part II. The spinal cord injured patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206508"} {"pmid": "4206509", "title": "Special needs of long-term patients.", "content": "Special needs of long-term patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206509"} {"pmid": "4206507", "title": "Cerebrospinal fluid pulsatile force and focal ventricular dilatation in cases of growing skull fracture.", "content": "Cerebrospinal fluid pulsatile force and focal ventricular dilatation in cases of growing skull fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206507"} {"pmid": "4206511", "title": "Characterization of echovirus types 7, 12, and 29 hemagglutinins for human and monkey erythrocytes.", "content": "Characterization of echovirus types 7, 12, and 29 hemagglutinins for human and monkey erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206511"} {"pmid": "4206512", "title": "The prevention of radiation-induced, early, transient incapacitation of monkeys by an antihistamine.", "content": "The prevention of radiation-induced, early, transient incapacitation of monkeys by an antihistamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206512"} {"pmid": "4206513", "title": "Effects of extracellular proteases on incorporation of amino acids into protein by isolated rat tissues.", "content": "Effects of extracellular proteases on incorporation of amino acids into protein by isolated rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206513"} {"pmid": "4206514", "title": "Inhibition of human platelet-collagen adhesion reaction by amitriptyline and imipramine.", "content": "Inhibition of human platelet-collagen adhesion reaction by amitriptyline and imipramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206514"} {"pmid": "4206515", "title": "Studies on the red cell and antibody-reactive sites of the parvovirus H-1: effect of fixatives.", "content": "Studies on the red cell and antibody-reactive sites of the parvovirus H-1: effect of fixatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206515"} {"pmid": "4206516", "title": "The role of demethylbetahistine in the depressor response to betahistine in the rat.", "content": "The role of demethylbetahistine in the depressor response to betahistine in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206516"} {"pmid": "4206517", "title": "Strain specificity of monodisperse gamma-globulin appearance after immunization of inbred mice.", "content": "Strain specificity of monodisperse gamma-globulin appearance after immunization of inbred mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206517"} {"pmid": "4206518", "title": "Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment.", "content": "Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206518"} {"pmid": "4206519", "title": "An anatomico-physiological principle governing the direction of the gastro-intestinal mucosal folds during life.", "content": "An anatomico-physiological principle governing the direction of the gastro-intestinal mucosal folds during life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206519"} {"pmid": "4206520", "title": "Carbenicillin-induced coagulopathy.", "content": "Carbenicillin-induced coagulopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206520"} {"pmid": "4206522", "title": "A new, highly susceptible laboratory animal for Chagas's disease.", "content": "A new, highly susceptible laboratory animal for Chagas's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206522"} {"pmid": "4206523", "title": "American trypanosomiasis: a new host.", "content": "American trypanosomiasis: a new host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206523"} {"pmid": "4206524", "title": "Infections with Plasmodium falciparum and Plasmodium vivax in the owl monkey--model systems for basic biological and chemotherapeutic studies.", "content": "Infections with Plasmodium falciparum and Plasmodium vivax in the owl monkey--model systems for basic biological and chemotherapeutic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206524"} {"pmid": "4206525", "title": "The trypanocidal action of human serum and of baboon plasma.", "content": "The trypanocidal action of human serum and of baboon plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206525"} {"pmid": "4206526", "title": "Letter: Sarcocystis in the Malaysian long-tailed monkey, Macaca irus.", "content": "Letter: Sarcocystis in the Malaysian long-tailed monkey, Macaca irus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206526"} {"pmid": "4206527", "title": "Letter: Malarial relapse mechanism.", "content": "Letter: Malarial relapse mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206527"} {"pmid": "4206528", "title": "Sarcosporidiosis in man.", "content": "Sarcosporidiosis in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206528"} {"pmid": "4206530", "title": "Proceedings: Attempted infection of chimpanzees and cats with Sarcocystis of cattle.", "content": "Proceedings: Attempted infection of chimpanzees and cats with Sarcocystis of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206530"} {"pmid": "4206529", "title": "Arbovirus studies in Nupeko forest, a possible natural focus of yellow fever virus in Nigeria. I. Description of the area and serological survey of humans and other vertebrate hosts.", "content": "Arbovirus studies in Nupeko forest, a possible natural focus of yellow fever virus in Nigeria. I. Description of the area and serological survey of humans and other vertebrate hosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206529"} {"pmid": "4206532", "title": "Proceedings: An infection of Klossiella muris Smith and Johnson, 1902, in a wild Mus musculus from Iran.", "content": "Proceedings: An infection of Klossiella muris Smith and Johnson, 1902, in a wild Mus musculus from Iran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206532"} {"pmid": "4206531", "title": "Experimental Trypanosoma cruzi infection in rhesus monkeys--the acute phase.", "content": "Experimental Trypanosoma cruzi infection in rhesus monkeys--the acute phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206531"} {"pmid": "4206533", "title": "Proceedings: Culture of Schistosoma haematobium and the effects of immune sera in vitro.", "content": "Proceedings: Culture of Schistosoma haematobium and the effects of immune sera in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206533"} {"pmid": "4206534", "title": "Chemical and physicochemical properties of two strains of tobacco streak virus.", "content": "Chemical and physicochemical properties of two strains of tobacco streak virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206534"} {"pmid": "4206535", "title": "LambdaattB-attP, a lambda derivative containing both sites involved in integrative recombination.", "content": "LambdaattB-attP, a lambda derivative containing both sites involved in integrative recombination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206535"} {"pmid": "4206536", "title": "Selective inhibition of viral protein accumulation in interferon-treated cells; nondiscriminate inhibition of the translation of added viral and cellular messenger RNAs in their extracts.", "content": "Selective inhibition of viral protein accumulation in interferon-treated cells; nondiscriminate inhibition of the translation of added viral and cellular messenger RNAs in their extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206536"} {"pmid": "4206537", "title": "Chromatic information processing in the foveal projection (area striata) of unanesthetized primate.", "content": "Chromatic information processing in the foveal projection (area striata) of unanesthetized primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206537"} {"pmid": "4206541", "title": "Effects of selective coronary hypotension and nitroglycerin or Bay a 1040 on the distribution of Rb86 clearance in the canine heart.", "content": "Effects of selective coronary hypotension and nitroglycerin or Bay a 1040 on the distribution of Rb86 clearance in the canine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206541"} {"pmid": "4206542", "title": "Effects of thyrotropin-releasing hormone (TRH) in maternal, fetal and newborn rats.", "content": "Effects of thyrotropin-releasing hormone (TRH) in maternal, fetal and newborn rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206542"} {"pmid": "4206543", "title": "The effect of caloric deprivation upon thyroid function in the neonatal rat.", "content": "The effect of caloric deprivation upon thyroid function in the neonatal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206543"} {"pmid": "4206544", "title": "Role of glucose as a regulator and precursor of amino acids in the pancreatic beta-cells.", "content": "Role of glucose as a regulator and precursor of amino acids in the pancreatic beta-cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206544"} {"pmid": "4206545", "title": "Aromatization by the immature rhesus monkey ovary.", "content": "Aromatization by the immature rhesus monkey ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206545"} {"pmid": "4206546", "title": "Cone mechanisms in the electroretinogram of the cynomolgus monkey.", "content": "Cone mechanisms in the electroretinogram of the cynomolgus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206546"} {"pmid": "4206547", "title": "Experimental ocular irradiation with accelerated protons.", "content": "Experimental ocular irradiation with accelerated protons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206547"} {"pmid": "4206538", "title": "Gargoylism--Hurlers syndrome.", "content": "Gargoylism--Hurlers syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206538"} {"pmid": "4206548", "title": "Citrate-Mg2+ transport in Bacillus subtilis. Studies with 2-fluoro-L-erythro-citrate as a substrate.", "content": "Citrate-Mg2+ transport in Bacillus subtilis. Studies with 2-fluoro-L-erythro-citrate as a substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206548"} {"pmid": "4206549", "title": "Studies on human beta-D-N-acetylhexosaminidases. 3. Biochemical genetics of Tay-Sachs and Sandhoff's diseases.", "content": "Studies on human beta-D-N-acetylhexosaminidases. 3. Biochemical genetics of Tay-Sachs and Sandhoff's diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206549"} {"pmid": "4206550", "title": "Generation of superoxide free radical during the autoxidation of thiols.", "content": "Generation of superoxide free radical during the autoxidation of thiols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206550"} {"pmid": "4206551", "title": "Characterization of the binding protein for epidermal growth factor.", "content": "Characterization of the binding protein for epidermal growth factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206551"} {"pmid": "4206552", "title": "Determination of the structure and conformation of bacterial polysaccharides by carbon 13 nuclear magnetic resonance. Studies on the group-specific antigens of Neisseria meningitidis serogroups A and X.", "content": "Determination of the structure and conformation of bacterial polysaccharides by carbon 13 nuclear magnetic resonance. Studies on the group-specific antigens of Neisseria meningitidis serogroups A and X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206552"} {"pmid": "4206553", "title": "Hetero-implants of epiphyseal cartilage in fracture gaps.", "content": "Hetero-implants of epiphyseal cartilage in fracture gaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206553"} {"pmid": "4206554", "title": "Immunological studies on the acidic chromogranins and on dopamine beta-hydroxylase (EC 1.14.2.1) of bovine chromaffin granules.", "content": "Immunological studies on the acidic chromogranins and on dopamine beta-hydroxylase (EC 1.14.2.1) of bovine chromaffin granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206554"} {"pmid": "4206555", "title": "Temperature-sensitive mutations affecting the regenerative sodium channel in Drosophila melanogaster.", "content": "Temperature-sensitive mutations affecting the regenerative sodium channel in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206555"} {"pmid": "4206556", "title": "Lactose loading test on protein calorie malnutrition.", "content": "Lactose loading test on protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206556"} {"pmid": "4206557", "title": "Clinical uses of central venous cannulation.", "content": "Clinical uses of central venous cannulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206557"} {"pmid": "4206559", "title": "Scattered radiation dosage as a function of x-ray energy.", "content": "Scattered radiation dosage as a function of x-ray energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206559"} {"pmid": "4206558", "title": "Comparison of electron beams from the Siemens betatron and the Sagittaire linear accelerator.", "content": "Comparison of electron beams from the Siemens betatron and the Sagittaire linear accelerator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206558"} {"pmid": "4206560", "title": "Physical characteristics of fast-neutron beams from a compact medical cyclotron.", "content": "Physical characteristics of fast-neutron beams from a compact medical cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206560"} {"pmid": "4206564", "title": "Compression osteosynthesis of lateral malleolar fractures with a figure-of-eight cerclage.", "content": "Compression osteosynthesis of lateral malleolar fractures with a figure-of-eight cerclage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206564"} {"pmid": "4206565", "title": "Studies on Crohn's disease. 3. Concentrations of immunoglobulins G, A, and M in the mucosa of the terminal ileum.", "content": "Studies on Crohn's disease. 3. Concentrations of immunoglobulins G, A, and M in the mucosa of the terminal ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206565"} {"pmid": "4206567", "title": "Effects of methoxyflurane and two metabolites on sodium transport in the toad bladder.", "content": "Effects of methoxyflurane and two metabolites on sodium transport in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206567"} {"pmid": "4206569", "title": "Mycetoma formation in Trichophyton rubrum infection.", "content": "Mycetoma formation in Trichophyton rubrum infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206569"} {"pmid": "4206571", "title": "Adjuvant long-term chemotherapy in complex treatment of operable breast cancer.", "content": "Adjuvant long-term chemotherapy in complex treatment of operable breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206571"} {"pmid": "4206570", "title": "Placental lactogen levels in rhesus isoimmunization.", "content": "Placental lactogen levels in rhesus isoimmunization. A prospective study of the plasma levels of human placental lactogen (HPL) in pregnancies complicated by rhesus isoimmunization showed that in mild and moderately affected cases the levels were normal, while in severely affected cases they were raised. Serial levels of HPL before the 26th week provide a valuable indication of fetal outcome, and we suggest that this estimation should be used routinely as an adjunct to other tests in the management of rhesus isoimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206570"} {"pmid": "4206572", "title": "Attempts to demonstrate \"tumor-globulin\" in sera of patients with malignant neoplasms.", "content": "Attempts to demonstrate \"tumor-globulin\" in sera of patients with malignant neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206572"} {"pmid": "4206573", "title": "Reversible increase in pulmonary vascular permeability after Pseudomonas aeruginosa bacteremia in unanesthetized sheep.", "content": "Reversible increase in pulmonary vascular permeability after Pseudomonas aeruginosa bacteremia in unanesthetized sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206573"} {"pmid": "4206576", "title": "Acrosomal proteinase inhibitors in rhesus monkey (Macaca mulatta) oviduct fluid.", "content": "Acrosomal proteinase inhibitors in rhesus monkey (Macaca mulatta) oviduct fluid. Acrosomal proteinase inhibitors were found in rhesus monkey fallopian tubes. Spermatozoa contain a proteolytic enzyme in their acrosomal heads and which would be adversely affected by the presence of acrosomal proteinase inhibitors. The inhibitor concentration was high before ovulation, decreased to low levels around the time of ovulation, and rose to high levels again within 1-3 days after ovulation. Alpha-1-antitrypsin, alpha-2-macroglobulin and alpha-1-antichymotrypsin all followed this high-low-high pattern. Alpha-1-antitrypsin in human cervical mucus is found to follow a similar waxing and waning according to progesterone secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206576"} {"pmid": "4206577", "title": "Uterine bleeding in the rhesus monkey in response to various designs of intrauterine devices.", "content": "Uterine bleeding in the rhesus monkey in response to various designs of intrauterine devices. To study quantitative menstrual blood loss (MBL), 10 normally rhesus monkeys and 18 ovariectomized, hormonally supplemented monkeys (estradiol and progesterone) were inserted with IUDs: a silastic cylinder and 3 modifications the polyethylene Tatum T device. A 92% increase (p.01) in MBL was noted in the Y-T device monkeys (n=7) and a 70% increase (p.05) in the large oval T ones (n=5). MBL was unaffected by the small oval T, and by the cylindrical Silastic devices after the second postinsertion period. Intermenstrual bleeding was observed in 4 of 7 Y-T device animals but was uncorrelated with MBL. It was concluded that rhesus monkeys may serve as good research models for designing human IUDs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206577"} {"pmid": "4206578", "title": "Oral contraceptive activity of danazol in the rhesus monkey.", "content": "Oral contraceptive activity of danazol in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206578"} {"pmid": "4206568", "title": "Functional morphology of the lining membrane of the middle ear and Eustachian tube: an overview.", "content": "Functional morphology of the lining membrane of the middle ear and Eustachian tube: an overview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206568"} {"pmid": "4206580", "title": "Physiological genetics of melanotic tumours in Drosophila melanogaster. VII. The relationship of dietary sterols to tumour penetrance.", "content": "Physiological genetics of melanotic tumours in Drosophila melanogaster. VII. The relationship of dietary sterols to tumour penetrance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206580"} {"pmid": "4206579", "title": "The role of mycoplasma infection in human reproductive failure.", "content": "The role of mycoplasma infection in human reproductive failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206579"} {"pmid": "4206581", "title": "A case for the abolition of long stay hospitals and beds.", "content": "A case for the abolition of long stay hospitals and beds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206581"} {"pmid": "4206582", "title": "Ejaculation by male rhesus in the absence of female partners.", "content": "Ejaculation by male rhesus in the absence of female partners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206582"} {"pmid": "4206574", "title": "Use of an elemental diet for intestinal disorders and for the critically ill.", "content": "Use of an elemental diet for intestinal disorders and for the critically ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206574"} {"pmid": "4206583", "title": "Glycogen synthetase and phosphorylase activities in different tissues of genetically obese mice.", "content": "Glycogen synthetase and phosphorylase activities in different tissues of genetically obese mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206583"} {"pmid": "4206584", "title": "Pituitary function in malnutrition.", "content": "Pituitary function in malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206584"} {"pmid": "4206575", "title": "Diverticulosis of the appendix: a collective review.", "content": "Diverticulosis of the appendix: a collective review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206575"} {"pmid": "4206585", "title": "Treatment of functional hypothyroidism by oral TRF monitored by daily urinary thyroxine and histamine assay.", "content": "Treatment of functional hypothyroidism by oral TRF monitored by daily urinary thyroxine and histamine assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206585"} {"pmid": "4206586", "title": "Bioassay and immunoassay measurements of serum thyrotropin in primary hypothyroidism before and after the administration of thyrotropin releasing hormone.", "content": "Bioassay and immunoassay measurements of serum thyrotropin in primary hypothyroidism before and after the administration of thyrotropin releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206586"} {"pmid": "4206587", "title": "Genetic marker systems in Arctic populations. II. Polymorphism of C'3 in Finnish Lapps.", "content": "Genetic marker systems in Arctic populations. II. Polymorphism of C'3 in Finnish Lapps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206587"} {"pmid": "4206588", "title": "Frequency of Gm, Inv and ISf phenotypes in the population of 4 Yugoslavian villages.", "content": "Frequency of Gm, Inv and ISf phenotypes in the population of 4 Yugoslavian villages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206588"} {"pmid": "4206589", "title": "Carbonic anhydrase II polymorphism in Africa.", "content": "Carbonic anhydrase II polymorphism in Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206589"} {"pmid": "4206591", "title": "B and T lymphocyte subpopulations in human peripheral blood.", "content": "B and T lymphocyte subpopulations in human peripheral blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206591"} {"pmid": "4206590", "title": "ABO and Rh blood groups in relation to sex ratio of sibs.", "content": "ABO and Rh blood groups in relation to sex ratio of sibs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206590"} {"pmid": "4206595", "title": "Technique for obtaining pure endometrial fluid from rhesus monkeys.", "content": "Technique for obtaining pure endometrial fluid from rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206595"} {"pmid": "4206593", "title": "Nonlethal deciliation of Tetrahymena by a local anesthetic and its utility as a tool for studying cilia regeneration.", "content": "Nonlethal deciliation of Tetrahymena by a local anesthetic and its utility as a tool for studying cilia regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206593"} {"pmid": "4206592", "title": "Histone F1 of Tetrahymena macronuclei: unique electrophoretic properties and phosphorylation of F1 in an amitotic nucleus.", "content": "Histone F1 of Tetrahymena macronuclei: unique electrophoretic properties and phosphorylation of F1 in an amitotic nucleus. Histone fraction F1 has been isolated and purified from macronuclei of the ciliated protozoan, Tetrahymena pyriformis. In many respects, Tetrahymena F1 is similar to that of other organisms. It is the only Tetrahymena histone soluble in 5% perchloric acid or 5% trichloroacetic acid, has a higher molecular weight than any other Tetrahymena histone, is the histone most easily dissociated from Tetrahymena chromatin, and is susceptible to specific proteolytic cleavage. However, unlike F1 in all other organisms, Tetrahymena F1 is not the slowest-migrating histone fraction when analyzed by polyacrylamide gel electrophoresis at low pH. Tetrahymena F1 also exhibits unusual behavior in sodium dodecyl sulfate-containing polyacrylamide gels, migrating faster than calf thymus F1 at pH 10, and slower than calf thymus F1 at pH 7.6. Tetrahymena F1 was found to be highly phosphorylated in rapidly growing cells, suggesting that the relationship between cell replication and F1 phosphorylation previously observed in mammalian cells may extend to all eukaryotes. The observation that extensive F1 phosphorylation occurs in macronuclei, which divide amitotically, argues against a unique role for F1 phosphorylation in the process of chromosome condensation at mitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206592"} {"pmid": "4206596", "title": "The effect of the concentration of golden hamster spermatozoa on the acrosome reaction and egg penetration in vitro.", "content": "The effect of the concentration of golden hamster spermatozoa on the acrosome reaction and egg penetration in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206596"} {"pmid": "4206594", "title": "Genetic control of mitochondrial thymidine kinase in human-mouse and monkey-mouse somatic cell hybrids.", "content": "Genetic control of mitochondrial thymidine kinase in human-mouse and monkey-mouse somatic cell hybrids. Distinctive thymidine (dT) kinase molecular forms are present in mouse, human, and monkey mitochondria. Disk polyacrylamide gel electrophoresis (disk PAGE) analyses have shown that the mitochondrial-specific dT kinases differ from cytosol dT kinases in relative electrophoretic mobilities (Rm). Furthermore, the mouse mitochondrial dT kinase differs in Rm value from primate mitochondrial dT kinases. The mouse and primate cytosol dT kinases can also be distinguished. Disk PAGE analyses have been carried out on the cytosol and mitochondrial dT kinases of human-mouse (WIL-8) and monkey-mouse (mK.CV(III)) somatic cell hybrids in order to learn whether the mitochondria of the hybrid cells contained murine mitochondrial-specific, primate mitochondrial-specific, or both dT kinases. WIL-8 cells were derived from cytosol dT kinase-negative, mitochondrial dT kinase-positive mouse fibro blasts and from cytosol dT kinase-positive, mitochondrial dT kinase-positive human embryonic lung cells; they contained mostly mouse chromosomes and a few human chromosomes, including the determinant for human cytosol dT kinase. The mK.CV(III) cells were derived from cytosol dT kinase-negative, mitochondrial dT kinase-positive mouse kidney cells and from cytosol dT kinase-positive, mitochondrial dT kinase-positive monkey kidney cells; they contained mostly mouse chromosomes and a few monkey chromosomes, including the determinant for monkey cytosol dT kinase. Disk PAGE analyses demonstrated that the mitochondria of human-mouse and monkey-mouse somatic cell hybrids contained the mouse-specific mitochondrial dT kinase but not the human- or monkey-specific mitochondrial dT kinase. These findings suggest that primate cytosol and mitochondrial thymidine kinase genes are coded on different chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206594"} {"pmid": "4206600", "title": "Biopsy of enlarged, superficial lymph nodes.", "content": "Biopsy of enlarged, superficial lymph nodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206600"} {"pmid": "4206601", "title": "Editorial: Pancreatic transplants: new wrinkles.", "content": "Editorial: Pancreatic transplants: new wrinkles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206601"} {"pmid": "4206597", "title": "Extracorporeal chemotherapy with L-asparaginase in man.", "content": "Extracorporeal chemotherapy with L-asparaginase in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206597"} {"pmid": "4206598", "title": "Everting ectopic ureteroceles.", "content": "Everting ectopic ureteroceles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206598"} {"pmid": "4206599", "title": "Symptomatic therapy in viral illness. A controlled study of effects on work performance.", "content": "Symptomatic therapy in viral illness. A controlled study of effects on work performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206599"} {"pmid": "4206602", "title": "Antenatal diagnosis and therapeutic trends in sphingolipidoses.", "content": "Antenatal diagnosis and therapeutic trends in sphingolipidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206602"} {"pmid": "4206603", "title": "Minocycline (minocin).", "content": "Minocycline (minocin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206603"} {"pmid": "4206605", "title": "Explanation of degree of correlation of sibling generation times in animal cells.", "content": "Explanation of degree of correlation of sibling generation times in animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206605"} {"pmid": "4206606", "title": "Autosomal recessive mutation in sugar response of Drosophila.", "content": "Autosomal recessive mutation in sugar response of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206606"} {"pmid": "4206607", "title": "Retardation of discrimination reversal by delta9-tetrahydrocannabinol in monkeys.", "content": "Retardation of discrimination reversal by delta9-tetrahydrocannabinol in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206607"} {"pmid": "4206614", "title": "Electrolyte compatibility in a synthetic amino acid hyperalimentation solution.", "content": "Electrolyte compatibility in a synthetic amino acid hyperalimentation solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206614"} {"pmid": "4206615", "title": "Monitoring the effectiveness of antimicrobial agents in a general hospital.", "content": "Monitoring the effectiveness of antimicrobial agents in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206615"} {"pmid": "4206612", "title": "Parenteral hyperalimentation--a quality of care survey and review.", "content": "Parenteral hyperalimentation--a quality of care survey and review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206612"} {"pmid": "4206613", "title": "Physiochemical considerations in intravenous hyperalimentation.", "content": "Physiochemical considerations in intravenous hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206613"} {"pmid": "4206616", "title": "Stability of parenteral solutions of cefazolin sodium.", "content": "Stability of parenteral solutions of cefazolin sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206616"} {"pmid": "4206619", "title": "Hyaluronidase effects on aqueous outflow resistance. Quantitative and localizing studies in the rhesus monkey eye.", "content": "Hyaluronidase effects on aqueous outflow resistance. Quantitative and localizing studies in the rhesus monkey eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206619"} {"pmid": "4206617", "title": "Primary malignant medulloepithelioma of the retinal stalk.", "content": "Primary malignant medulloepithelioma of the retinal stalk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206617"} {"pmid": "4206618", "title": "Experimental retinal detachment in the owl monkey. 10. The early receptor poential.", "content": "Experimental retinal detachment in the owl monkey. 10. The early receptor poential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206618"} {"pmid": "4206620", "title": "The effect of tobramycin on rabbit eyes.", "content": "The effect of tobramycin on rabbit eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206620"} {"pmid": "4206621", "title": "The effect of tobramycin on gentamicin-resistant strains in Pseudomonas keratitis.", "content": "The effect of tobramycin on gentamicin-resistant strains in Pseudomonas keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206621"} {"pmid": "4206608", "title": "Cholinergic influence on intravenous cocaine self-administration by rhesus monkeys.", "content": "Cholinergic influence on intravenous cocaine self-administration by rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206608"} {"pmid": "4206609", "title": "Acute tolerance to the effects of delta-9-tetrahydrocannabinol on spaced responding by monkeys.", "content": "Acute tolerance to the effects of delta-9-tetrahydrocannabinol on spaced responding by monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206609"} {"pmid": "4206622", "title": "The zoogeography of Polychromophilus and description of a new species of a gregarine (Lankesteria galliardi).", "content": "The zoogeography of Polychromophilus and description of a new species of a gregarine (Lankesteria galliardi).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206622"} {"pmid": "4206624", "title": "Letter: Prey-predator transmission in the epizootiology of ovine sarcosporidiosis.", "content": "Letter: Prey-predator transmission in the epizootiology of ovine sarcosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206624"} {"pmid": "4206625", "title": "Mechanics of ciliary locomotion.", "content": "Mechanics of ciliary locomotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206625"} {"pmid": "4206626", "title": "Fibrous dysplastic lesions of the jaws in Nigerians.", "content": "Fibrous dysplastic lesions of the jaws in Nigerians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206626"} {"pmid": "4206637", "title": "Distribution of the Kell blood groups in the Spanish population.", "content": "Distribution of the Kell blood groups in the Spanish population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206637"} {"pmid": "4206640", "title": "Detection of relationships among microsporidan isolates by electrophoretic analysis: hydrophobic extracts.", "content": "Detection of relationships among microsporidan isolates by electrophoretic analysis: hydrophobic extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206640"} {"pmid": "4206642", "title": "The effect of cryosurgery on peripheral nerves.", "content": "The effect of cryosurgery on peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206642"} {"pmid": "4206638", "title": "The retinotectal projection from a double-ventral compound eye in Xenopus laevis.", "content": "The retinotectal projection from a double-ventral compound eye in Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206638"} {"pmid": "4206639", "title": "Germ cell migration in toad (Bufo bufo): effect of ventral grafting of embryonic dorsal regions.", "content": "Germ cell migration in toad (Bufo bufo): effect of ventral grafting of embryonic dorsal regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206639"} {"pmid": "4206641", "title": "Detection of relationships among microsporidan isolates by electrophoretic analysis: hydrophilic extracts.", "content": "Detection of relationships among microsporidan isolates by electrophoretic analysis: hydrophilic extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206641"} {"pmid": "4206644", "title": "Intravenous hyperalimentation in cancer patients.", "content": "Intravenous hyperalimentation in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206644"} {"pmid": "4206643", "title": "An immunologic rationale for suture line recurrence in carcinoma of the colon.", "content": "An immunologic rationale for suture line recurrence in carcinoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206643"} {"pmid": "4206645", "title": "Family structure, child location and nutritional disease in rural Haiti.", "content": "Family structure, child location and nutritional disease in rural Haiti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206645"} {"pmid": "4206646", "title": "Letter: Hyperosmolar diabetic coma--ketotic and nonketotic.", "content": "Letter: Hyperosmolar diabetic coma--ketotic and nonketotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206646"} {"pmid": "4206648", "title": "Study reveals increases--in costs, in per diem rates, and in per diem expenditures.", "content": "Study reveals increases--in costs, in per diem rates, and in per diem expenditures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206648"} {"pmid": "4206649", "title": "Associative learning of Drosophila melanogaster.", "content": "Associative learning of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206649"} {"pmid": "4206650", "title": "Negative reinforcing properties of morphine-antagonists in naive rhesus monkeys.", "content": "Negative reinforcing properties of morphine-antagonists in naive rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206650"} {"pmid": "4206658", "title": "Association of pili with rough colony type of Moraxella bovis.", "content": "Association of pili with rough colony type of Moraxella bovis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206658"} {"pmid": "4206657", "title": "African swine fever: detection of antibody by reverse single radial immunodiffusion.", "content": "African swine fever: detection of antibody by reverse single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206657"} {"pmid": "4206659", "title": "Scanning isoelectric focusing in small density-gradient colums. 3. A method for detailed mapping of biological activity of column contents applied to pea lipoxygenase.", "content": "Scanning isoelectric focusing in small density-gradient colums. 3. A method for detailed mapping of biological activity of column contents applied to pea lipoxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206659"} {"pmid": "4206655", "title": "Allergic reaction patterns in relation to age, sex, season, eosinophilia and some genetic marker systems.", "content": "Allergic reaction patterns in relation to age, sex, season, eosinophilia and some genetic marker systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206655"} {"pmid": "4206654", "title": "Homocytotropic antibody in schistosomiasis mansoni.", "content": "Homocytotropic antibody in schistosomiasis mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206654"} {"pmid": "4206660", "title": "Affinity chromatography of carbonic anhydrase.", "content": "Affinity chromatography of carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206660"} {"pmid": "4206661", "title": "The nose as a model for the study of respiratory tract allergic disease.", "content": "The nose as a model for the study of respiratory tract allergic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206661"} {"pmid": "4206662", "title": "Fractionation and chemical characterization studies on Micropolyspora faeni antigens.", "content": "Fractionation and chemical characterization studies on Micropolyspora faeni antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206662"} {"pmid": "4206663", "title": "Immunology of byssinosis: a study of the reactions between the isolated byssinosis \"antigen\" and human immunoglobulins.", "content": "Immunology of byssinosis: a study of the reactions between the isolated byssinosis \"antigen\" and human immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206663"} {"pmid": "4206667", "title": "Root-end closure techniques including apexification.", "content": "Root-end closure techniques including apexification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206667"} {"pmid": "4206666", "title": "Alpha crystallin subunits in the bovine lens.", "content": "Alpha crystallin subunits in the bovine lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206666"} {"pmid": "4206664", "title": "Characterization of reaction centers from photosynthetic bacteria. II. Amino acid composition of the reaction center protein and its subunits in Rhodopseudomonas spheroides R-26.", "content": "Characterization of reaction centers from photosynthetic bacteria. II. Amino acid composition of the reaction center protein and its subunits in Rhodopseudomonas spheroides R-26.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206664"} {"pmid": "4206665", "title": "Alpha-keto esters as substrates of erythrocyte carbonic anhydrase. Kinetic studies of enzyme-catalyzed hydration of methyl and ethyl pyruvate.", "content": "Alpha-keto esters as substrates of erythrocyte carbonic anhydrase. Kinetic studies of enzyme-catalyzed hydration of methyl and ethyl pyruvate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206665"} {"pmid": "4206671", "title": "Thyrotropin response to thyrotropin releasing hormone in normal subjects.", "content": "Thyrotropin response to thyrotropin releasing hormone in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206671"} {"pmid": "4206672", "title": "Activity of neurons in the lower precentral cortex during voluntary and rhythmical jaw movements in the monkey.", "content": "Activity of neurons in the lower precentral cortex during voluntary and rhythmical jaw movements in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206672"} {"pmid": "4206675", "title": "Diclonal and multiple gammopathies.", "content": "Diclonal and multiple gammopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206675"} {"pmid": "4206673", "title": "Homologues of the human M-N blood types in gorillas and other non-human primates.", "content": "Homologues of the human M-N blood types in gorillas and other non-human primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206673"} {"pmid": "4206674", "title": "Glycolytic intermediates and adenine nucleotides of human platelets. I. The influence of ACD and EDTA anticoagulants.", "content": "Glycolytic intermediates and adenine nucleotides of human platelets. I. The influence of ACD and EDTA anticoagulants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206674"} {"pmid": "4206680", "title": "Basilar membrane tuning curves in the guinea pig.", "content": "Basilar membrane tuning curves in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206680"} {"pmid": "4206647", "title": "An evaluation of the latex agglutination test for the detection of hepatitis associated antigen.", "content": "An evaluation of the latex agglutination test for the detection of hepatitis associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206647"} {"pmid": "4206681", "title": "Evidence from Mössbauer experiments for nonlinear vibration in the cochlea.", "content": "Evidence from Mössbauer experiments for nonlinear vibration in the cochlea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206681"} {"pmid": "4206689", "title": "Study indicates which patients nurses don't like: the unpleasant, the long-term, the mentally ill, the hypochondriacs, and the dying.", "content": "Study indicates which patients nurses don't like: the unpleasant, the long-term, the mentally ill, the hypochondriacs, and the dying.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206689"} {"pmid": "4206690", "title": "Biologic monitor is best test of ETO sterilizer.", "content": "Biologic monitor is best test of ETO sterilizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206690"} {"pmid": "4206692", "title": "Membrane-to-membrane interactions in mitochondria treated with basic proteins.", "content": "Membrane-to-membrane interactions in mitochondria treated with basic proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206692"} {"pmid": "4206685", "title": "Foci of degeneration produced by measles virus in cell cultures with antibody-free liquid medium.", "content": "Foci of degeneration produced by measles virus in cell cultures with antibody-free liquid medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206685"} {"pmid": "4206684", "title": "The significance of post-traumatic status epilepticus in childhood.", "content": "The significance of post-traumatic status epilepticus in childhood. Five cases of early post-traumatic status epilepticus in childhood are reported. In all cases the trauma was apparently of a minor nature and the seizures appeared within two hours after injury. In none of the cases was a significant intracranial clot detected, nor was lasting cerebral damage evident. This is in contrast with adults, where status epilepticus after head injury is thought to be an ominous sign. Rapid improvement in level of consciousness after prompt treatment is certainly the most important criterion in assessing the role of the seizures. In the same period of time, post-traumatic status epilepticus was not seen in children with more severe head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206684"} {"pmid": "4206696", "title": "The relationship of a caprine mycoplasma to PG3, the type strain of Mycoplasma mycoides subsp. capri.", "content": "The relationship of a caprine mycoplasma to PG3, the type strain of Mycoplasma mycoides subsp. capri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206696"} {"pmid": "4206697", "title": "Incidence and significance of mycoplasmas in sick cats.", "content": "Incidence and significance of mycoplasmas in sick cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206697"} {"pmid": "4206698", "title": "Influence and use of the employ of disodium cromoglycate \"DSCG\" on circadian rhythms in pulmonary mechanics.", "content": "Influence and use of the employ of disodium cromoglycate \"DSCG\" on circadian rhythms in pulmonary mechanics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206698"} {"pmid": "4206677", "title": "Platelet aggregation by ristocetin in EDTA plasma: extension clumping with high concentrations of EDTA.", "content": "Platelet aggregation by ristocetin in EDTA plasma: extension clumping with high concentrations of EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206677"} {"pmid": "4206703", "title": "Reaginic antibodies and helminth infection.", "content": "Reaginic antibodies and helminth infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206703"} {"pmid": "4206676", "title": "Preprothrombin and prothrombin in full-term newborns.", "content": "Preprothrombin and prothrombin in full-term newborns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206676"} {"pmid": "4206706", "title": "Clinical symptoms induced by E. coli endotoxin in goats.", "content": "Clinical symptoms induced by E. coli endotoxin in goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206706"} {"pmid": "4206705", "title": "Hydroxyproline excretion in bovine puerperal paresis with special reference to bone resorption.", "content": "Hydroxyproline excretion in bovine puerperal paresis with special reference to bone resorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206705"} {"pmid": "4206714", "title": "Intraluminal diverticulum of the duodenum--cass report and review of the literature.", "content": "Intraluminal diverticulum of the duodenum--cass report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206714"} {"pmid": "4206715", "title": "Congenital hemihypertrophy with abnormalities of the aortic arch, and of the skeletal, cutaneous and ocular systems.", "content": "Congenital hemihypertrophy with abnormalities of the aortic arch, and of the skeletal, cutaneous and ocular systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206715"} {"pmid": "4206716", "title": "Whole body counting using a twin-detector scanner.", "content": "Whole body counting using a twin-detector scanner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206716"} {"pmid": "4206719", "title": "Preliminary observations on the influence of proflavin, ethidium bromide and elevated temperature on the production of the antibiotic nisin by Streptococcus lactis strains.", "content": "Preliminary observations on the influence of proflavin, ethidium bromide and elevated temperature on the production of the antibiotic nisin by Streptococcus lactis strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206719"} {"pmid": "4206720", "title": "Changes occurring in proteins of bull semen plasma owing to inflammatory conditions of the efferent ducts.", "content": "Changes occurring in proteins of bull semen plasma owing to inflammatory conditions of the efferent ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206720"} {"pmid": "4206723", "title": "A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states.", "content": "A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206723"} {"pmid": "4206726", "title": "Clinical and microbiological evaluation of pivampicillin in the treatment of urinary tract infections.", "content": "Clinical and microbiological evaluation of pivampicillin in the treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206726"} {"pmid": "4206725", "title": "Nefopam hydrochloride for pain relief.", "content": "Nefopam hydrochloride for pain relief.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206725"} {"pmid": "4206724", "title": "Treadmill exercise-tolerance test behavior in anginal patients treated with perhexiline maleate.", "content": "Treadmill exercise-tolerance test behavior in anginal patients treated with perhexiline maleate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206724"} {"pmid": "4206727", "title": "Effect of candicidin on fungal flora of the gastrointestinal tract.", "content": "Effect of candicidin on fungal flora of the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206727"} {"pmid": "4206728", "title": "Single-session, two-dose therapy with doxycycline for gonorrhea.", "content": "Single-session, two-dose therapy with doxycycline for gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206728"} {"pmid": "4206729", "title": "\"Combination\" anti-asthmatic therapy: recent developments.", "content": "\"Combination\" anti-asthmatic therapy: recent developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206729"} {"pmid": "4206730", "title": "Study of the serum half life of lividomycin in uraemic patients.", "content": "Study of the serum half life of lividomycin in uraemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206730"} {"pmid": "4206718", "title": "The possible role of the dog in the epidemiology of ovine sarcosporidiosis.", "content": "The possible role of the dog in the epidemiology of ovine sarcosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206718"} {"pmid": "4206732", "title": "Doxycycline in renal insufficiency.", "content": "Doxycycline in renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206732"} {"pmid": "4206731", "title": "Comparative serum theophylline levels following the oral administration of elixophyllin and somophyllino-O, a new preparation of aminophylline.", "content": "Comparative serum theophylline levels following the oral administration of elixophyllin and somophyllino-O, a new preparation of aminophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206731"} {"pmid": "4206733", "title": "A pharmacologic evaluation of fluoxymesterone in normal men.", "content": "A pharmacologic evaluation of fluoxymesterone in normal men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206733"} {"pmid": "4206735", "title": "Relapse in chronic urinary tract infection in a child due to Salmonella brandenburg.", "content": "Relapse in chronic urinary tract infection in a child due to Salmonella brandenburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206735"} {"pmid": "4206736", "title": "The place of general practice.", "content": "The place of general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206736"} {"pmid": "4206742", "title": "Methods for the measurement of chloroplast volume and structure in vitro and in vivo.", "content": "Methods for the measurement of chloroplast volume and structure in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206742"} {"pmid": "4206743", "title": "Acid-base indicator for the measurement of rapid changes in hydrogen ion concentration.", "content": "Acid-base indicator for the measurement of rapid changes in hydrogen ion concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206743"} {"pmid": "4206744", "title": "Nitrogen fixation--assay methods and techniques.", "content": "Nitrogen fixation--assay methods and techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206744"} {"pmid": "4206745", "title": "Hydrogen ion buffers.", "content": "Hydrogen ion buffers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206745"} {"pmid": "4206748", "title": "Visual stimulus control of intracranial self-stimulation in the squirrel monkey (Saimiri sciureus).", "content": "Visual stimulus control of intracranial self-stimulation in the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206748"} {"pmid": "4206749", "title": "Prefrontal lesions alter eating and hoarding behavior in rats.", "content": "Prefrontal lesions alter eating and hoarding behavior in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206749"} {"pmid": "4206751", "title": "The operational definition of human attachment.", "content": "The operational definition of human attachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206751"} {"pmid": "4206752", "title": "Organic factors and psychophysiology in childhood schizophrenia.", "content": "Organic factors and psychophysiology in childhood schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206752"} {"pmid": "4206760", "title": "Antibiotics produced by Streptomyces. IX. Heptafungin-A, a new heptaene macrolide antibiotic.", "content": "Antibiotics produced by Streptomyces. IX. Heptafungin-A, a new heptaene macrolide antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206760"} {"pmid": "4206762", "title": "Effect of DDT and sevin on soil fungi.", "content": "Effect of DDT and sevin on soil fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206762"} {"pmid": "4206761", "title": "Regulated biosynthesis of protease and alpha-amylase in Bacillus subtilis.", "content": "Regulated biosynthesis of protease and alpha-amylase in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206761"} {"pmid": "4206763", "title": "Phenotypic derepression of enzymes of the isoleucine-valine pathway by isoleucine in Pseudomonas aeruginosa.", "content": "Phenotypic derepression of enzymes of the isoleucine-valine pathway by isoleucine in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206763"} {"pmid": "4206765", "title": "Proceedings: New outlook on the epidemiology and epizoology of listeriosis.", "content": "Proceedings: New outlook on the epidemiology and epizoology of listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206765"} {"pmid": "4206764", "title": "Serological relationship between Pseudomonas aeruginosa and Enterobacteriaceae. I. Relationship of Pseudomonas aeruginosa O antigens to Salmonella, Arizona and Citrobacter.", "content": "Serological relationship between Pseudomonas aeruginosa and Enterobacteriaceae. I. Relationship of Pseudomonas aeruginosa O antigens to Salmonella, Arizona and Citrobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206764"} {"pmid": "4206766", "title": "Proceedings: Listeria monocytogenes: some biochemical and serological aspects.", "content": "Proceedings: Listeria monocytogenes: some biochemical and serological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206766"} {"pmid": "4206767", "title": "Proceedings: Listeriosis: its veterinary hygienic significance in Hungary.", "content": "Proceedings: Listeriosis: its veterinary hygienic significance in Hungary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206767"} {"pmid": "4206771", "title": "Proceedings: Ability of Listeria monocytogenes strains to attack carbohydrates and related compounds.", "content": "Proceedings: Ability of Listeria monocytogenes strains to attack carbohydrates and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206771"} {"pmid": "4206770", "title": "Proceedings: Phosphatase activity of listeria.", "content": "Proceedings: Phosphatase activity of listeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206770"} {"pmid": "4206769", "title": "Proceedings: Biological properties of virulent and avirulent Listeria monocytogenes strains.", "content": "Proceedings: Biological properties of virulent and avirulent Listeria monocytogenes strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206769"} {"pmid": "4206768", "title": "Proceedings: Present situation of human listeriosis in Hungary.", "content": "Proceedings: Present situation of human listeriosis in Hungary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206768"} {"pmid": "4206772", "title": "Proceedings: Listeria monocytogenes-haemolysin: lecithinase.", "content": "Proceedings: Listeria monocytogenes-haemolysin: lecithinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206772"} {"pmid": "4206773", "title": "Proceedings: Flagellation in virulent and avirulent Listeria monocytogenes strains.", "content": "Proceedings: Flagellation in virulent and avirulent Listeria monocytogenes strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206773"} {"pmid": "4206774", "title": "Proceedings: Survival versus growth of a facultative psychrotroph.", "content": "Proceedings: Survival versus growth of a facultative psychrotroph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206774"} {"pmid": "4206775", "title": "Proceedings: Experience with nalidixic acid-trypaflavine agar.", "content": "Proceedings: Experience with nalidixic acid-trypaflavine agar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206775"} {"pmid": "4206776", "title": "Proceedings: Methods to isolate Listeria monocytogenes from different materials.", "content": "Proceedings: Methods to isolate Listeria monocytogenes from different materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206776"} {"pmid": "4206777", "title": "Proceedings: Differential media for the isolation of Listeria monocytogenes.", "content": "Proceedings: Differential media for the isolation of Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206777"} {"pmid": "4206778", "title": "Proceedings: Listeriosis in professionally exposed persons.", "content": "Proceedings: Listeriosis in professionally exposed persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206778"} {"pmid": "4206779", "title": "Proceedings: Screening examination for listeriosis in pregnancy.", "content": "Proceedings: Screening examination for listeriosis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206779"} {"pmid": "4206780", "title": "Proceedings: Serological screening of pregnant women for listeriosis.", "content": "Proceedings: Serological screening of pregnant women for listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206780"} {"pmid": "4206781", "title": "Proceedings: Listeriosis in puerperal women and their infants.", "content": "Proceedings: Listeriosis in puerperal women and their infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206781"} {"pmid": "4206783", "title": "Proceedings: Tetracycline treatment of pregnant women with suspected listeriosis.", "content": "Proceedings: Tetracycline treatment of pregnant women with suspected listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206783"} {"pmid": "4206782", "title": "Proceedings: Listeriosis and gestation.", "content": "Proceedings: Listeriosis and gestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206782"} {"pmid": "4206784", "title": "Proceedings: Congenital listeriosis.", "content": "Proceedings: Congenital listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206784"} {"pmid": "4206785", "title": "Proceedings: Involvement of the central nervous system in neonatal listeriosis.", "content": "Proceedings: Involvement of the central nervous system in neonatal listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206785"} {"pmid": "4206786", "title": "Proceedings: Listeric meningitis: report of a case.", "content": "Proceedings: Listeric meningitis: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206786"} {"pmid": "4206787", "title": "Proceedings: The pathogenicity of Listeria monocytogenes.", "content": "Proceedings: The pathogenicity of Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206787"} {"pmid": "4206789", "title": "Proceedings: Pathogenicity of Listeria monocytogenes in the rat.", "content": "Proceedings: Pathogenicity of Listeria monocytogenes in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206789"} {"pmid": "4206788", "title": "Proceedings: An outbreak of listeriosis in domestic rabbits.", "content": "Proceedings: An outbreak of listeriosis in domestic rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206788"} {"pmid": "4206790", "title": "Proceedings: Active immunization with formol vaccine against sheep listeriosis.", "content": "Proceedings: Active immunization with formol vaccine against sheep listeriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206790"} {"pmid": "4206791", "title": "Proceedings: Abortion in Gray's monkey (Cercopithecus mona) associated with Listeria monocytogenes.", "content": "Proceedings: Abortion in Gray's monkey (Cercopithecus mona) associated with Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206791"} {"pmid": "4206793", "title": "The major dilemma of mental retardation: shall we prevent it? (Some social implications of research in mental retardation).", "content": "The major dilemma of mental retardation: shall we prevent it? (Some social implications of research in mental retardation).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206793"} {"pmid": "4206796", "title": "Immunoglobulins in aqueous humor and iris from endogenous uveitis and cataract patients.", "content": "Immunoglobulins in aqueous humor and iris from endogenous uveitis and cataract patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206796"} {"pmid": "4206797", "title": "Microsurgical studies. II. Corneal endothelial healing and posterior wound closure after \"through and through\" suturing.", "content": "Microsurgical studies. II. Corneal endothelial healing and posterior wound closure after \"through and through\" suturing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206797"} {"pmid": "4206798", "title": "Aphakic soft contact lenses. I. A clinical and bacteriological study.", "content": "Aphakic soft contact lenses. I. A clinical and bacteriological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206798"} {"pmid": "4206799", "title": "Comparison of methods used for solubilization of human erythrocyte membrane protein.", "content": "Comparison of methods used for solubilization of human erythrocyte membrane protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206799"} {"pmid": "4206800", "title": "The attachment of IgG molecules on the red cell surface.", "content": "The attachment of IgG molecules on the red cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206800"} {"pmid": "4206801", "title": "Non-specific attachment of IgG to erythrocytes.", "content": "Non-specific attachment of IgG to erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206801"} {"pmid": "4206802", "title": "Methyldopa-induced erythrocyte binding IgG: another model of nonspecific attachment of immunoglobulins to erythrocytes.", "content": "Methyldopa-induced erythrocyte binding IgG: another model of nonspecific attachment of immunoglobulins to erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206802"} {"pmid": "4206804", "title": "Studies on the pyocins of Pseudomonas aeruginosa: morphology and mode of action of contractile pyocins.", "content": "Studies on the pyocins of Pseudomonas aeruginosa: morphology and mode of action of contractile pyocins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206804"} {"pmid": "4206803", "title": "Studies on the pyocins of Pseudomonas aeruginosa: production of contractile and flexuous pyocins in Pseudomonas aeruginosa.", "content": "Studies on the pyocins of Pseudomonas aeruginosa: production of contractile and flexuous pyocins in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206803"} {"pmid": "4206805", "title": "The inhibition of growth of Escherichia coli spheroplasts by antibacterial agents.", "content": "The inhibition of growth of Escherichia coli spheroplasts by antibacterial agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206805"} {"pmid": "4206807", "title": "Childhood lead poisoning: medical review.", "content": "Childhood lead poisoning: medical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206807"} {"pmid": "4206806", "title": "The bioassay of rubratoxins A and B using Tetrahymena pyriformis strain W.", "content": "The bioassay of rubratoxins A and B using Tetrahymena pyriformis strain W.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206806"} {"pmid": "4206795", "title": "Effect of pH on Blepharisma intermedium. 2. Cytochemical changes.", "content": "Effect of pH on Blepharisma intermedium. 2. Cytochemical changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206795"} {"pmid": "4206808", "title": "Synthesis and antibacterial properties of substituted decylbarbituric acids.", "content": "Synthesis and antibacterial properties of substituted decylbarbituric acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206808"} {"pmid": "4206809", "title": "2-Ethylpyridine derivatives with antitubercular properties.", "content": "2-Ethylpyridine derivatives with antitubercular properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206809"} {"pmid": "4206811", "title": "Use of Medicaid payment files for medical care research.", "content": "Use of Medicaid payment files for medical care research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206811"} {"pmid": "4206810", "title": "Community hospitals and Medicaid.", "content": "Community hospitals and Medicaid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206810"} {"pmid": "4206812", "title": "Quality and cost control: Medicare and beyond.", "content": "Quality and cost control: Medicare and beyond.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206812"} {"pmid": "4206815", "title": "New treatment for acanthosis nigricans.", "content": "New treatment for acanthosis nigricans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206815"} {"pmid": "4206818", "title": "Antimicrobial activity of sodium copper chlorophyllin.", "content": "Antimicrobial activity of sodium copper chlorophyllin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206818"} {"pmid": "4206822", "title": "Prevalence of Neisseria meningitidis serogroups in Egypt.", "content": "Prevalence of Neisseria meningitidis serogroups in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206822"} {"pmid": "4206823", "title": "Results and appraisal of a nutrition survey in Malawi.", "content": "Results and appraisal of a nutrition survey in Malawi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206823"} {"pmid": "4206824", "title": "Amino acid ratios in protein-energy malnutrition.", "content": "Amino acid ratios in protein-energy malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206824"} {"pmid": "4206825", "title": "Distribution, biotransformation and excretion of bupivacaine in the rat and the monkey.", "content": "Distribution, biotransformation and excretion of bupivacaine in the rat and the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206825"} {"pmid": "4206826", "title": "Acute gonorrheal proctitis.", "content": "Acute gonorrheal proctitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206826"} {"pmid": "4206827", "title": "Effect of oxytetracycline, doxycycline and folic acid on nitrogen balance during parenteral nutrition.", "content": "Effect of oxytetracycline, doxycycline and folic acid on nitrogen balance during parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206827"} {"pmid": "4206830", "title": "Unresponsiveness to thyrotropin-releasing hormone (TRH) in treated Graves' hyperthyroidism and in euthyroid Graves' disease.", "content": "Unresponsiveness to thyrotropin-releasing hormone (TRH) in treated Graves' hyperthyroidism and in euthyroid Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206830"} {"pmid": "4206829", "title": "15N studies of endogenous faecal nitrogen in infants.", "content": "15N studies of endogenous faecal nitrogen in infants. (15)N from labelled yeast protein, fed to marasmic and recovered infants, appeared in the stool shortly after administration and continued to be excreted for 100 hours. Unabsorbed dietary (15)N, which appeared with carmine-marked stools, formed only part of this excretion. Calculations of the endogenous nitrogen content of infant stool agreed closely with those of previous workers. The use of intravenously injected (15)N showed that part of the stool nitrogen was derived from this source. It was excreted as urea, ammonia, and other compounds, and totalled about 2% of the administered urea. The persistence of the (15)N in the stool suggests that it had in part been incorporated into cellular material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206829"} {"pmid": "4206831", "title": "Thyroxine-binding-globulin (T.B.G.) deficiency and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in the same family.", "content": "Thyroxine-binding-globulin (T.B.G.) deficiency and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in the same family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206831"} {"pmid": "4206832", "title": "Comparison of serum prolactin and thyrotropin responses to thyrotropin-releasing hormone in patients with Graves' ophthalmopathy.", "content": "Comparison of serum prolactin and thyrotropin responses to thyrotropin-releasing hormone in patients with Graves' ophthalmopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206832"} {"pmid": "4206833", "title": "The inhibition of infection by cucumber mosaic virus and influenza virus by extracts from Phytolacca americana.", "content": "The inhibition of infection by cucumber mosaic virus and influenza virus by extracts from Phytolacca americana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206833"} {"pmid": "4206834", "title": "Physico-chemical evidence for the re-classification of the caliciviruses.", "content": "Physico-chemical evidence for the re-classification of the caliciviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206834"} {"pmid": "4206835", "title": "Serological studies with purified neuraminidase antigens of influenza B viruses.", "content": "Serological studies with purified neuraminidase antigens of influenza B viruses. Neuraminidase (N) can be extracted from virus particles of influenza B strains by treatment with trypsin, in a form which is free from the viral HA and has specific immunological activity. The N antigen of B/LEE/40 behaves differently from that of 1965-6 strains in gel diffusion and enzyme inhibition tests with animal antisera raised by infection or by artificial immunization with the homologous or heterologous strains. The frequency and titres of NI antibody detected in human sera by B/LEE antigen are different from those found with antigen from B/Eng/13/65. The latter antibody appears to contribute to the effect of serum HI antibody in protecting volunteers exposed to a deliberate intranasal challenge infection of the B/Eng/13/65 strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206835"} {"pmid": "4206836", "title": "Selective elimination of Enterobacteriaceae species from the digestive tract in mice and monkeys.", "content": "Selective elimination of Enterobacteriaceae species from the digestive tract in mice and monkeys. In mice and in monkeys, ;selective' elimination of Enterobacteriaceae species from the digestive tract of animals with a sensitive flora was accomplished by oral treatment with nalidixic acid (1 mg./g. body weight in mice and 0.4 mg./g. body weight in monkeys). During treatment, the concentration of enterococci (and also of Candida albicans in the monkey) remained unaltered. This indicates that the fraction of the anaerobic microflora which is responsible for the colonization resistance of the digestive tract is not affected by the treatment. An important consequence seems to be, that elimination of yeast and fungi with fungistatic drugs can be started at the same time as elimination of Enterobacteriaceae is attempted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206836"} {"pmid": "4206838", "title": "Exposure to hepatitis B virus and development of the chronic HBAg carrier state in children.", "content": "Exposure to hepatitis B virus and development of the chronic HBAg carrier state in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206838"} {"pmid": "4206837", "title": "Mechanism of depigmentation by hydroquinone.", "content": "Mechanism of depigmentation by hydroquinone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206837"} {"pmid": "4206839", "title": "Posthypoglycemic hyperglycemia in diabetic children.", "content": "Posthypoglycemic hyperglycemia in diabetic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206839"} {"pmid": "4206840", "title": "Meningiomas of childhood and adolescence.", "content": "Meningiomas of childhood and adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206840"} {"pmid": "4206842", "title": "Fucosidosis: clinical, biochemical, immunologic, and genetic studies in two new cases.", "content": "Fucosidosis: clinical, biochemical, immunologic, and genetic studies in two new cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206842"} {"pmid": "4206841", "title": "The Winchester syndrome: a nonlysosomal connective tissue disease.", "content": "The Winchester syndrome: a nonlysosomal connective tissue disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206841"} {"pmid": "4206843", "title": "Therapeutic implications of electrolyte, water, and nitrogen losses during recovery from protein-calorie malnutrition.", "content": "Therapeutic implications of electrolyte, water, and nitrogen losses during recovery from protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206843"} {"pmid": "4206845", "title": "Models of the saccadic eye movement control system.", "content": "Models of the saccadic eye movement control system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206845"} {"pmid": "4206851", "title": "Chemical nature of monogenean sclerites. I. Stabilization of clamp-protein by formation of dityrosine.", "content": "Chemical nature of monogenean sclerites. I. Stabilization of clamp-protein by formation of dityrosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206851"} {"pmid": "4206855", "title": "Immunochemical cross-reactivity between the dissociated capsid proteins of PVY group plant viruses.", "content": "Immunochemical cross-reactivity between the dissociated capsid proteins of PVY group plant viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206855"} {"pmid": "4206847", "title": "Production of aflatoxin by cultures derived from conidia stored in the laboratory.", "content": "Production of aflatoxin by cultures derived from conidia stored in the laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206847"} {"pmid": "4206859", "title": "Are silicone rubber T-tubes better than latex rubber tubes in the common bile duct? A rhesus monkey model.", "content": "Are silicone rubber T-tubes better than latex rubber tubes in the common bile duct? A rhesus monkey model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206859"} {"pmid": "4206858", "title": "The effect of malnutrition on the pattern of growth in the rat kidney and the renal response to acidosis.", "content": "The effect of malnutrition on the pattern of growth in the rat kidney and the renal response to acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206858"} {"pmid": "4206860", "title": "Radical total glossectomy.", "content": "Radical total glossectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206860"} {"pmid": "4206863", "title": "Simple and complex spike activities of the cerebellar Purkinje cell in relation to selective alternate movement in intact monkey.", "content": "Simple and complex spike activities of the cerebellar Purkinje cell in relation to selective alternate movement in intact monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206863"} {"pmid": "4206862", "title": "Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia.", "content": "Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206862"} {"pmid": "4206864", "title": "Studies on the control of some simple motor tasks. V. Changes in motor output following dorsal root section in squirrel monkey.", "content": "Studies on the control of some simple motor tasks. V. Changes in motor output following dorsal root section in squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206864"} {"pmid": "4206865", "title": "What constitutes adequate medical therapy for the patient with angina pectoris?", "content": "What constitutes adequate medical therapy for the patient with angina pectoris?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206865"} {"pmid": "4206861", "title": "Letter: CCNU in teatment of recurrent medulloblastoma.", "content": "Letter: CCNU in teatment of recurrent medulloblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206861"} {"pmid": "4206868", "title": "Clonal analysis of cell division in the Bacillus subtilis div IV-B1 minicell-producing mutant.", "content": "Clonal analysis of cell division in the Bacillus subtilis div IV-B1 minicell-producing mutant. Spores of the Bacillus subtilis minicell-producing mutant div IV-B1 were germinated and grown to microcolonies in chambers which facilitate continuous observation of the developing clones with a phase-contrast microscope. Time lapse photographs were taken of 46 clones, covering the period from the beginning of outgrowth until at least two rounds of cell division had been completed. Cell lineages were constructed from contour length measurements of the photographs. These data include cell lengths, division site locations, and cell numbers in clones of various ages. From these data we have determined that the probability of a minicell being produced at any division by the div IV-B1 mutant is 0.31. The location of the abnormal division site which generates the first minicell produced in the outgrowing clone appears to be random with respect to the existing cell poles. In contrast, the location of the second abnormal division site, and hence the second minicell, is not random but rather occurs preferentially in proximity to the first minicell. This clustering of abnormal events suggests that division site location is related to pole age (generations), although other influences on minicell clustering cannot be ruled out at present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206868"} {"pmid": "4206866", "title": "Transcriptional control in the L-arabinose operon of Escherichia coli B-r.", "content": "Transcriptional control in the L-arabinose operon of Escherichia coli B-r. The structural genes involved in l-arabinose metabolism are regulated by the protein product of the araC gene. This protein functions as both an activator and repressor of enzyme synthesis in this gene complex. Using lambdah80dara deoxyribonucleic acid in hybridization studies, we have shown that the ara operon, including structural genes araB, araA, and araD, is transcribed in the direction araB to araD and that initiation of transcription of these genes requires an active araC gene. The half-life of this message, approximately 3 min at 30 C, is the same in the presence or absence of the araC protein in the activator state. However, an unexplained 2-min lag in decay of ara messenger ribonucleic acid that does not occur in decay of lac messenger ribonucleic acid is observed. This lag period requires activated araC protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206866"} {"pmid": "4206867", "title": "Direct enzymatic repair of deoxyribonucleic acid single-strand breaks in dormant spores.", "content": "Direct enzymatic repair of deoxyribonucleic acid single-strand breaks in dormant spores. With the alkaline sucrose gradient centrifugation method, it was found that dormant spores of Clostridium botulinum subjected to 300 krads of gamma radiation showed a distinct decrease in deoxyribonucleic acid (DNA) fragment size, indicating induction of single-strand breaks (SSB). A two- to threefold difference in radiation resistance of spores of two strains of C. botulinum, 33A (37% survival dose [D(37)] = 110 krads) and 51B (D(37) = 47 krads), was accompanied by relatively larger DNA fragments (molecular weight 7.9 x 10(7)) obtained during extraction from the radiation-resistant strain 33A and smaller DNA fragments (molecular weight 1.8 x 10(7)) obtained under identical conditions from radiation-sensitive strain 51B. The apparent number of DNA SSB produced by 300 krads in strains 33A and 51B was 0.37 and 3.50, respectively, per 10(8) daltons of DNA. Addition of 0.02 M ethylenediaminetetraacetic acid (EDTA) to spore suspensions during irradiation doubled the apparent number of SSB in strain 33A but had no effect on strain 51B. In vivo, 0.02 M EDTA present during irradiation to 100 to 300 krads decreased survival of spores of 33A by about 30% but had little or no effect on 51B. Survival of 33A was also reduced by about 45% when the spores were irradiated while frozen in dry ice (-75 C) and, after irradiation, immediately exposed to 0.03 M EDTA for 1 h to inhibit repair in the dormant spores. These results suggest that the highly radiation-resistant strain 33A may be able to accomplish repair of SSB during irradiation or after irradiation under nonphysiological conditions, i.e., in the dormant state. This repair can be inhibited by EDTA. Sedimentation patterns show that DNA from spores of both strains 33A and 51B did not show any postirradiation repair during the first 6 h of germination, as opposed to Bacillus subtilis spores, which exhibit repair immediately after germination. These observations suggest the existence of direct repair in physiological dormant spores of strain 33A in the cryptobiotic resting state in the absence of germination. The repair seems to be similar to that of polynucleotide ligase activity shown to be operative in some vegetative cells. Apparently radiation-sensitive strains such as 51B and B. subtilis are generally poor in DNA repair enzyme activity under conditions of spore dormancy, which may account for the approximately threefold difference in radiation sensitivity or DNA fragility of different strains, or both.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206867"} {"pmid": "4206869", "title": "Amino-terminal sequence of the tryptophan synthetase alpha chain of Bacillus subtilis.", "content": "Amino-terminal sequence of the tryptophan synthetase alpha chain of Bacillus subtilis. The sequence of the 46 NH(2)-terminal residues of the tryptophan synthetase alpha chain of Bacillus subtilis was determined and compared with the corresponding sequences of Escherichia coli, Shigella dysenteriae, Salmonella typhimurium, Aerobacter aerogenes, Serratia marcescens, and Pseudomonas putida. A deletion of six residues was found at the NH(2)-terminal end of the alpha chain of B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206869"} {"pmid": "4206870", "title": "Use of ultraviolet radiation to locate dipicolinic acid in Bacillus cereus spores.", "content": "Use of ultraviolet radiation to locate dipicolinic acid in Bacillus cereus spores. A novel method is described that allows a direct determination of the location of a portion of the dipicolinic acid (DPA) in spores. Ultraviolet (UV) irradiation is shown to cause cross-linkage of DPA to spore proteins which have the characteristics of membrane proteins. We suggest that DPA resides in the inner forespore membrane (IFSM) and spore cytoplasm (i.e., the spore protoplast). Only that portion of the DPA in the vicinity of the IFSM appeared to form UV-induced DPA-protein adducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206870"} {"pmid": "4206871", "title": "Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R: partial purification and properties of methionyl-transfer ribonucleic acid synthetase and methionyl-transfer ribonucleic acid formyltransferase.", "content": "Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R: partial purification and properties of methionyl-transfer ribonucleic acid synthetase and methionyl-transfer ribonucleic acid formyltransferase. The initiation of protein synthesis by Streptococcus faecalis R grown in folate-free culture occurs without N-formylation or N-acylation of methionyl-tRNA(f) (Met). Methionyl-tRNA synthetase and methionyl-tRNA formyltransferase were partially purified from S. faecalis grown under normal culture conditions in the presence of folate (plus-folate); the general properties of the enzymes were determined and compared with the properties of the enzymes purified from wild-type cells grown in the absence of folate (minus-folate). S. faecalis methionyl-tRNA synthetase displays optimal activity at pH values between 7.2 and 7.8, requires Mg(2+), and has an apparent molecular weight of 106,000, as determined by gel filtration, and 127,000, as determined by sucrose density gradient centrifugation. The K(m) values of plus-folate methionyl-tRNA synthetase for each of the three substrates in the aminoacylation reaction (l-methionine, adenosine triphosphate, and tRNA) are nearly identical to the respective substrate Michaelis constants of minus-folate methionyl-tRNA synthetase. Furthermore, both plus- and minus-folate S. faecalis methionyl-tRNA synthetases catalyze, at equal rates, the aminoacylation of tRNA(f) (Met) and tRNA(m) (Met) isolated from either plus-folate or minus-folate cells. S. faecalis methionyl-tRNA formyltransferase displays optimal activity at pH values near 7.0, is stimulated by Mg(2+), and has an apparent molecular weight of approximately 29,900 when estimated by sucrose density gradient centrifugation. The K(m) value of plus-folate formyltransferase for plus-folate Met-tRNA(f) (Met) does not differ significantly from that of minus-folate formyltransferase for minus-folate Met-tRNA(f) (Met). Both enzymes can utilize either 10-formyltetrahydrofolate or 10-formyltetrahydropteroyltriglutamate as the formyl donor; the Michaelis constant for the monoglutamyl pteroyl coenzyme is slightly less than that of the triglutamyl pteroyl coenzyme for both transformylases. Tetrahydrofolate and uncharged tRNA(f) (Met) are competitive inhibitors of both plus- and minus-folate S. faecalis formyltransferase; folic acid, pteroic acid, aminopterin, and Met-tRNA(m) (Met) are not inhibitory. These results indicate that the presence or absence of folic acid in the culture medium of S. faecalis has no apparent effect on either methionyl-tRNA synthetase or methionyl-tRNA formyltransferase, the two enzymes directly involved in the formation of formylmethionyl-tRNA(f) (Met). Therefóre, the lack of N-formylation of Met-tRNA(f) (Met) in minus-folate S. faecalis is due to the absence of the formyl donor, a 10-formyl-tetrahydropteroyl derivative. Although the general properties of S. faecalis methionyl-tRNA synthetase are similar to those of other aminoacyl-tRNA synthetases, S. faecalis methionyl-tRNA formyltransferase differs from other previously described transformylases in certain kinetic parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206871"} {"pmid": "4206872", "title": "Phospholipid metabolism and membrane synthesis during sporulation in Bacillus megaterium.", "content": "Phospholipid metabolism and membrane synthesis during sporulation in Bacillus megaterium. In view of previously published reports of localized membrane growth in exponentially growing Bacillus megaterium and in sporulating Bacillus cereus, an attempt was made to describe phospholipid metabolism and the topology of membrane synthesis during sporulation in B. megaterium. The cells were pulsed with radioactive glycerol or acetate at the time of septum formation, and the specific activity of the lipid fraction was measured at various times through the free spore stage. The bulk of the material labeled during septation could not be recovered in the spore. Rather, it was found that the labeled lipid fraction underwent considerable turnover during spore development. Additionally, other experiments revealed that the lipid made before the initiation of sporulation was also subject to extensive turnover. In order to minimize both the confounding effects of lipid turnover and the possible presence of lateral diffusion of labeled lipid in the membrane, autoradiography of cells pulse labeled with radioactive glycerol at the time of septation was performed; a symmetrical grain distribution resulted. Thus, despite previously published suggestions to the contrary, the current experimental techniques could not demonstrate the existence of localized membrane synthesis in B. megaterium during sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206872"} {"pmid": "4206873", "title": "Glucose transport in Brucella abortus.", "content": "Glucose transport in Brucella abortus. Brucella abortus British strain 19 transported glucose with an apparent K(m) of 0.16 mM and an apparent V(max) of 250 nmol per min per mg of N. The only common glucose analogue transported was 2-deoxyglucose (2-DOG), with an apparent K(i) of 0.73 mM. Alpha- or beta-methyl glucosides and 3-O-methylglucose were not transported. Transport was linear for 70 to 90 s, depending on the concentration of substrate used. 2-Deoxyglucose was transported as the free sugar and was not further metabolized once inside the cell. There was no glucose phosphoenolpyruvate phosphotransferase system (PEP-PTS) present, and there were no inhibitors present in Brucella cell-free extract that inhibited the Escherichia coli glucose PEP-PTS. N-Ethylmaleimide (NEM) and p-chloromercuribenzoate (pCMB) completely inhibited transport of glucose and 2-DOG. Glutathione, dithiothreitol, and beta-mercaptoethanol reversed the effects of pCMB but not of NEM. A pH optimum of 7.2 and a temperature optimum of 37 to 45 C were observed for both K(m) and V(max). The glucose transport system appeared to be constitutive for glucose transport in cells grown on fructose, galactose, erythritol, or glucose. The electron transfer inhibitors carbonyl cyanide, m-chlorophenylhydrazone, NaN(3), 2,4-dinitrophenol, and KCN inhibited 2-DOG transport to a greater extent than did the metabolic energy inhibitors NaAsO(4), iodoacetate, KF, and 2-heptyl-4-hydroxyquinoline-N-oxide. Dicyclohexylcarbodiimide, an inhibitor of membrane-bound adenosine triphosphatases, inhibited transport by 100%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206873"} {"pmid": "4206875", "title": "Exclusion of induced bacteriophage from cells of a lysogenic Bacillus megaterium committed to sporulation.", "content": "Exclusion of induced bacteriophage from cells of a lysogenic Bacillus megaterium committed to sporulation. Spontaneous release of the temperate bacteriophage T (phiT), carried by Bacillus megaterium 899a, occurred during early growth of the host cells. Rejuvenated cells (accomplished by a 5x dilution in fresh medium) and unrejuvenated cells were induced by mitomycin C during the course of sporulation and subsequent phage phiT production measured by burst size. Induction of sequential samples of unrejuvenated cells resulted in burst sizes that fell to zero as T(0) sporulation time in the main culture was approached. This drop in burst size was not considered a sporulation event, as it also occurred during analogous stages of growth in an asporogenous mutant. Rejuvenated, induced portions of the culture of sporulating cells of B. megaterium 899a gave large burst sizes until T(+2), when the burst sizes fell to zero. The stage I asporogenous mutant, treated in a similar manner, gave lower, but still substantial, burst sizes; thus, the sharp decline in burst size of induced rejuvenated sporulating cells appeared to be a sporulation event. Sporulating cells induced at times shortly after T(1.5) formed spores in which the induced phage were trapped until germination of the spores, which formed infectious centers. This induced phage-trapping was maximal when the sporulating cultures were induced at T(2.25). Commitment to sporulation could be defined by our system as that point beyond which rejuvenated sporulating cells were unable to support the replication of the phage. This point also correlated with the increase in induced phage-trapping by spores. Two other methods gave a similar commitment time. Commitment to sporulation, in spite of added glucose or fresh complex medium, occurred at the same time. Electron micrography showed that the committed cell was still undergoing engulfment. The fate of induced phage phiT was determined at different points during growth and sporulation. Induction at times prior to T(0), which were longer than the eclipse period of the phage, resulted in a burst size of approximately 50. At times prior to T(0), shorter than the phage eclipse period, induction led to lysis with low burst sizes, approaching zero. The pattern of spontaneous phage release during growth was similar. From T(0) up to the point of commitment to sporulation, induction resulted in the blocking of spore formation without lysis. At the commitment point, induced phage were trapped and carried into spores which germinated to give infectious centers. The spontaneous derepression of phage at a time which blocked spore formation led to 7 x 10(4) infectious centers per ml and would not normally be noticed. Derepression at the time of phage entrapment was not observed to occur without induction with mitomycin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206875"} {"pmid": "4206874", "title": "Subunit cell wall of Sulfolobus acidocaldarius.", "content": "Subunit cell wall of Sulfolobus acidocaldarius. The cell wall of Sulfolobus acidocaldarius has been isolated. Cells were mechanically disrupted with a French press, and the cytoplasmic membrane was removed by extracting cell-envelope fragments with Triton X-100. The Triton-insoluble cell wall material retained the characteristic subunit structure when examined in the electron microscope. Isolated cell wall fragments formed in open sheets that were easily separated from cytoplasmic contamination. Chemical studies showed that the Triton-insoluble cell wall fragments consisted of lipoprotein with small amounts of carbohydrate and hexosamine. The amino acid composition indicated a highly charged hydrophobic cell surface. The presence of diaminopimelic acid with only traces of muramic acid indicates that the cell envelope does not have a rigid peptidoglycan layer. The results of chemical analyses and electron microscopy suggest a wall-membrane interaction stabilizing the cell envelope. The chemical and physical properties of this type of cell envelope would appear to form the basis for a new major division of bacteria with the definitive characteristics of a morphologically distinct subunit cell wall devoid of peptidoglycan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206874"} {"pmid": "4206876", "title": "Properties and developmental roles of the lysyl- and tryptophanyl-transfer ribonucleic acid synthetases of Bacillus subtilis: common genetic origin of the corresponding spore and vegetative enzymes.", "content": "Properties and developmental roles of the lysyl- and tryptophanyl-transfer ribonucleic acid synthetases of Bacillus subtilis: common genetic origin of the corresponding spore and vegetative enzymes. The lysyl-transfer ribonucleic acid synthetase (LRS) and tryptophanyl-transfer ribonucleic acid synthetases (TRS) (l-lysine:tRNA ligase [AMP], EC 6.1.1.6; and l-tryptophan:tRNA ligase [AMP], EC 6.1.1.2) have been purified 60- and 100-fold, respectively, from vegetative cells and spores of Bacillus subtilis. There are no significant differences between the corresponding spore and vegetative enzymes with respect to their elution characteristics from columns of phosphocellulose or hydroxylapatite, their molecular weight (~130,000 for LRS and ~87,000 for TRS as determined by gel filtration), their kinetic constants for substrates (in the amino acid-dependent adenosine triphosphate-pyrophosphate exchange reaction), and the kinetics of inactivation by heat and by antibody. The Mg(2+) requirement for optimal enzyme activity of the corresponding spore and vegetative enzyme differ slightly. Mutants having defective (temperature sensitive) vegetative LRS or TRS activities produce spores in which these enzymes are also defective. The mutant spores are more heat sensitive than the parental type, but contain normal levels of dipicolinic acid. They germinate normally at the restrictive temperature (43 C), but are blocked at specific developmental stages in outgrowth. No modification in temperature sensitivity phenotype occurs during outgrowth, nor is there a change in molecular weight of the two enzymes. The implication is that the LRS and TRS activities of the vegetative and spore stages are each coded (at least in part) by the same structural gene. The temperature sensitivity of mutant spores is discussed with respect to those factors which are involved in the formation of the heat-resistant state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206876"} {"pmid": "4206877", "title": "Alloantibodies and Australia antigen after open heart surgery.", "content": "Alloantibodies and Australia antigen after open heart surgery. The development of irregular serum antibodies (alloantibodies) following massive transfusion was studied in 144 patients who had undergone cardiac valve replacement. An overall incidence of alloimmunization of 8.3% was found. Of the 15 antibodies detected nine were Rhesus anti-E and four anti-Kell. The incidence of anti-E formation in Rhesus E-negative patients was 11.4%; the corresponding figure for anti-Kell was 3.2%. The results suggest that the risk of allo-immunization is directly related to the volume of blood transfused, and Rhesus E-negative persons appear to be at particular risk. Australia (Au) antigen investigations were also carried out in 102 of these cases. Three patients were Au antigen positive, one of them developing acute hepatitis. In each case no Au antigen could be detected in the donor blood that was used. It is suggested that tests for alloantibodies and for the Australia antigen should become part of the routine follow-up of any patient receiving massive transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206877"} {"pmid": "4206878", "title": "Host-parasite relationship in echinococcosis. I. Parasite biomass and antibody response in three strains of inbred mice against graded doses of Echinococcus multilocularis cysts.", "content": "Host-parasite relationship in echinococcosis. I. Parasite biomass and antibody response in three strains of inbred mice against graded doses of Echinococcus multilocularis cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206878"} {"pmid": "4206882", "title": "Leucocytozoon grusi sp. n. (Sporozoa: Leucocytozoidae) from a sandhill crane, Grus canadensis (L.).", "content": "Leucocytozoon grusi sp. n. (Sporozoa: Leucocytozoidae) from a sandhill crane, Grus canadensis (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206882"} {"pmid": "4206879", "title": "Observations on the relapse activity of Plasmodium simiovale in the rhesus monkey.", "content": "Observations on the relapse activity of Plasmodium simiovale in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206879"} {"pmid": "4206880", "title": "Immunofluorescent staining of plasmodial oocysts in the mosquito.", "content": "Immunofluorescent staining of plasmodial oocysts in the mosquito.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206880"} {"pmid": "4206881", "title": "Experimental infection of monkeys with Nanophyetus salmincola.", "content": "Experimental infection of monkeys with Nanophyetus salmincola.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206881"} {"pmid": "4206883", "title": "Parasites of golden trout from California.", "content": "Parasites of golden trout from California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206883"} {"pmid": "4206884", "title": "Effect of immune rabbit IgG on the primary immune response to Trichinella spiralis in mice.", "content": "Effect of immune rabbit IgG on the primary immune response to Trichinella spiralis in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206884"} {"pmid": "4206885", "title": "Embryonic neuropathy. A hypothesis of neural chest injury as the pathogenesis of congenital malformations.", "content": "Embryonic neuropathy. A hypothesis of neural chest injury as the pathogenesis of congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206885"} {"pmid": "4206886", "title": "Rh(D) immunization after massive transfusion of Rh(D)-positive blood.", "content": "Rh(D) immunization after massive transfusion of Rh(D)-positive blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206886"} {"pmid": "4206888", "title": "Red blood cell velocity in nailfold capillaries of man measured by a television microscopy technique.", "content": "Red blood cell velocity in nailfold capillaries of man measured by a television microscopy technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206888"} {"pmid": "4206887", "title": "Inhibition of Pseudomonas aeruginosa by ascorbic acid acting singly and in combination with antimicrobials: in-vitro and in-vivo studies.", "content": "Inhibition of Pseudomonas aeruginosa by ascorbic acid acting singly and in combination with antimicrobials: in-vitro and in-vivo studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206887"} {"pmid": "4206889", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 19-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 19-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206889"} {"pmid": "4206892", "title": "Schwann cell and myelin changes caused by some toxic agents and trauma.", "content": "Schwann cell and myelin changes caused by some toxic agents and trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206892"} {"pmid": "4206893", "title": "Temporomandibular arthropathy.", "content": "Temporomandibular arthropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206893"} {"pmid": "4206895", "title": "Letter: Mycetoma.", "content": "Letter: Mycetoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206895"} {"pmid": "4206894", "title": "South American trypanosomiasis (Chagas' disease).", "content": "South American trypanosomiasis (Chagas' disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206894"} {"pmid": "4206899", "title": "The effects of early malnutrition in man on body composition and adipose tissue cellularity at adult age.", "content": "The effects of early malnutrition in man on body composition and adipose tissue cellularity at adult age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206899"} {"pmid": "4206900", "title": "A clinical syndrome with inborn defect in erythropoiesis, dysplastic kidneys, eye lesions, malformation of the teeth and impaired hearing. A new syndrome in a 28-year-old woman.", "content": "A clinical syndrome with inborn defect in erythropoiesis, dysplastic kidneys, eye lesions, malformation of the teeth and impaired hearing. A new syndrome in a 28-year-old woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206900"} {"pmid": "4206901", "title": "Evaluation of primate allografts following treatment with immuosuppression and ameroid constrictors.", "content": "Evaluation of primate allografts following treatment with immuosuppression and ameroid constrictors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206901"} {"pmid": "4206902", "title": "A technique for the prevention of pneumothorax in pulmonary aspiration biopsy.", "content": "A technique for the prevention of pneumothorax in pulmonary aspiration biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206902"} {"pmid": "4206903", "title": "Evidence for a retinohypothalamic pathway in the golden hamster.", "content": "Evidence for a retinohypothalamic pathway in the golden hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206903"} {"pmid": "4206904", "title": "IgG, IgA, IgM, and IgD antiglobulins in juvenile rheumatoid arthritis.", "content": "IgG, IgA, IgM, and IgD antiglobulins in juvenile rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206904"} {"pmid": "4206905", "title": "Identification of bacteria from blood and joint fluids of human subjects as Bacillus licheniformis.", "content": "Identification of bacteria from blood and joint fluids of human subjects as Bacillus licheniformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206905"} {"pmid": "4206906", "title": "Articular and cutaneous manifestations of gonorrhoea. Review of sixteen cases.", "content": "Articular and cutaneous manifestations of gonorrhoea. Review of sixteen cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206906"} {"pmid": "4206907", "title": "A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors.", "content": "A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors. A new method is described for plotting kinetic results for inhibited enzyme-catalysed reactions. It provides a simple way of determining the inhibition constant, K'(i), of an uncompetitive, mixed or non-competitive inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206907"} {"pmid": "4206908", "title": "Preparation of some immobilized linked enzyme systems and their use in the automated determination of disaccharides.", "content": "Preparation of some immobilized linked enzyme systems and their use in the automated determination of disaccharides. 1. Glucose oxidase (EC 1.1.3.4), amyloglucosidase (EC 3.2.1.3), invertase (EC 3.2.1.26) and beta-galactosidase (EC 3.2.1.23) were covalently attached via glutaraldehyde to the inside surface of nylon tube. 2. The linked enzyme system, comprising invertase immobilized within a nylon tube acting in series with glucose oxidase immobilized in a similar way, was used for the automated determination of sucrose. 3. The linked enzyme system, comprising beta-galactosidase immobilized within a nylon tube acting in series with glucose oxidase immobilized in a similar way, was used for the automated determination of lactose. 4. The linked enzyme system, comprising amyloglucosidase immobilized within a nylon tube acting in series with glucose oxidase immobilized in a similar way, was used for the automated determination of maltose. 5. Mixtures of glucose oxidase and amyloglucosidase were immobilized within the same piece of nylon tube and used for the automated determination of maltose. 6. Mixtures of glucose oxidase and invertase were immobilized within the same piece of nylon tube and used for the automated determination of sucrose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206908"} {"pmid": "4206910", "title": "Inhibition of enzymes by metal ion-chelating reagents. Theory and new graphical methods of study.", "content": "Inhibition of enzymes by metal ion-chelating reagents. Theory and new graphical methods of study. 1. The mechanism of inhibition of enzymes by metal ion-chelating reagents is discussed and equations derived. 2. Two distinct mechanisms are postulated and graphical methods are given for differentiating between them. 3. Where the metal ion is actually removed from the enzyme to form a co-ordination complex in solution, a procedure is described for obtaining the stability constant for metal-enzyme interaction, the number of metal ions involved and the stoicheiometry of metal ion-ligand interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206910"} {"pmid": "4206909", "title": "Distribution of sulphate and iduronic acid residues in heparin and heparan sulphate.", "content": "Distribution of sulphate and iduronic acid residues in heparin and heparan sulphate. 1. A method was developed for determination of the uronic acid composition of heparin-like glycosaminoglycans. Polymers or oligosaccharides are degraded to monosaccharides by a combination of acid hydrolysis and deamination with HNO(2). The resulting uronic acid monosaccharides (accounting for about 70% of the uronic acid contents of the starting materials) are isolated and converted into the corresponding aldono-1,4-lactones, which are separated by g.l.c. The calculated ratios of glucuronic acid/iduronic acid are reproducible within 5%. 2. Samples of heparin from pig intestinal mucosa (molar ratio of sulphate/disaccharide unit, 2.40) and heparan sulphate from human aorta (sulphate/disaccharide ratio, 0.46) were subjected to uronic acid analysis. l-Iduronic acid constituted 77% and 19% respectively of the total uronic acid contents. 3. The correlation between the contents of sulphate and iduronic acid indicated by this finding also applied to the fractionated deamination products of the two polymers. The sulphated fragments varied in size from disaccharide to octasaccharide (or larger) and showed sulphate/disaccharide molar ratios in the range of 0.05-2.0. The proportion of iduronic acid increased with increasing ester sulphate contents of the oligosaccharides. 4. Previous studies on the biosynthesis of heparin in a cell-free system have shown that l-iduronic acid residues are formed by C-5 epimerization of d-glucuronic acid units at the polymer level; the process requires concomitant sulphation of the polymer. The results obtained in the present structural study conform to these findings, and suggest further that similar mechanisms may operate in the biosynthesis of heparan sulphate. The epimerization reaction appears to be linked to the sulphation of hydroxyl groups but does not seem to require sulphation of the target uronic acid residues. The significance of sulphamino groups in relation to the formation of iduronic acid is unknown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206909"} {"pmid": "4206911", "title": "Inhibition of enzymes by metal ion-chelating reagents. The action of copper-chelating reagents on diamine oxidase.", "content": "Inhibition of enzymes by metal ion-chelating reagents. The action of copper-chelating reagents on diamine oxidase. 1. The inhibition of diamine oxidase has been studied by using the following copper-chelating reagents: 1,10-phenanthroline; 2,2'-bipyridyl; 8-hydroxyquinoline (oxine); diethyldithiocarbamate and dithio-oxamide (rubeanic acid). 2. Addition of chelating reagent caused a rapid inhibition of enzyme to a degree dependent solely on the final inhibitor concentration. Addition of substrate gave linear initial rates of reaction showing that under these conditions the inhibition was not being rapidly reversed. 3. The inhibition has been investigated by using new graphical methods and has been found in all cases to involve the chelating agents completely removing two Cu(2+) ions from the enzyme. An alternative possibility, involving ligand substitution, was eliminated. 4. A value of K=8.0x10(-33)m(-2) has been found for the enzyme in equilibrium with 2 Cu(2+) ions (i.e. beta(2), the stability constant for diamine oxidase/two Cu(2+), is 32.1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206911"} {"pmid": "4206912", "title": "The molecular weight of J chains derived from human immunoglobulin M.", "content": "The molecular weight of J chains derived from human immunoglobulin M. J chain was isolated from sulphonated human immunoglobulin M molecules by electrophoresis on polyacrylamide gels. When determined by electrophoresis in sodium dodecyl sulphate-polyacrylamide gels, the molecular weight of the protein was about 27000. After suspension in 5m-guanidine hydrochloride solution for 21 days, two groups of three bands appeared on the gels. Most of the protein dissociated to components of molecular weight 15000. The molecular weight of purified J chain was also determined by ultracentrifugation. In borate-saline solution the average weight-average molecular weight was about 29000. The molecular weight slowly decreased upon prolonged exposure to guanidine hydrochloride, and after 14 days the minimum molecular weight was about 15000. Some association between chains still existed. These data suggest that J chain derived from the paraprotein exists in borate-saline solution as dimers held by strong non-covalent forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206912"} {"pmid": "4206913", "title": "The incorporation of J chain into reassembled human immunoglobulin M.", "content": "The incorporation of J chain into reassembled human immunoglobulin M. Human IgM (immunoglobulin M) was reduced with 24mm-mercaptoethylamine. This atreatment resulted in complete dissociation to IgMs subunits and free J chain. Intr-subunit interchain disulphide bonds remained intact. The mixture then was encouraged to reoxidize. The schlieren pattern of the reoxidized mixture showed the presence of a considerable quantity of IgM in addition to residual IgMs. The isolated reassembled IgM did not dissociate in 5m-guanidinium hydrochloride. It apparently contained the same amount of covalently attached J chain as did native IgM. The J chain was a part of the high-molecular-weight Fc fragment obtained from the reassembled IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206913"} {"pmid": "4206914", "title": "A new case of mu heavy chain disease: clinical and immunochemical studies.", "content": "A new case of mu heavy chain disease: clinical and immunochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206914"} {"pmid": "4206915", "title": "Granulocyte transfusions in leukopenic dogs: in vivo and in vitro function of granulocytes obtained by continuous-flow filtration leukopheresis.", "content": "Granulocyte transfusions in leukopenic dogs: in vivo and in vitro function of granulocytes obtained by continuous-flow filtration leukopheresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206915"} {"pmid": "4206916", "title": "Placental transfer of 14C labelled succinylcholine in near-term Macaca mulatta monkeys.", "content": "Placental transfer of 14C labelled succinylcholine in near-term Macaca mulatta monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206916"} {"pmid": "4206917", "title": "Vestibular nucleus units in alert monkeys are also influenced by moving visual fields.", "content": "Vestibular nucleus units in alert monkeys are also influenced by moving visual fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206917"} {"pmid": "4206918", "title": "Immunohistochemical localization and immunoelectrophoresis of cholinergic synaptic vesicle protein constituents from the Torpedo.", "content": "Immunohistochemical localization and immunoelectrophoresis of cholinergic synaptic vesicle protein constituents from the Torpedo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206918"} {"pmid": "4206919", "title": "Neocortical and limbic lesion effects on primate phonation.", "content": "Neocortical and limbic lesion effects on primate phonation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206919"} {"pmid": "4206926", "title": "Serum gold levels during chrysotherapy with relation to urinary and fecal excretion.", "content": "Serum gold levels during chrysotherapy with relation to urinary and fecal excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206926"} {"pmid": "4206920", "title": "Digital rectal examination.", "content": "Digital rectal examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206920"} {"pmid": "4206927", "title": "Evaluation of albutoin as an antiepileptic drug.", "content": "Evaluation of albutoin as an antiepileptic drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206927"} {"pmid": "4206928", "title": "Trypanosoma cruzi: protection of mice with epimastigote antigens from immunologically different parasite strains.", "content": "Trypanosoma cruzi: protection of mice with epimastigote antigens from immunologically different parasite strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206928"} {"pmid": "4206929", "title": "Influence of methods of preparation on the infectivity, agglutination, activity, and ultrastructure of bloodstream trypanosomes.", "content": "Influence of methods of preparation on the infectivity, agglutination, activity, and ultrastructure of bloodstream trypanosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206929"} {"pmid": "4206930", "title": "Schistosoma mansoni: IgG and IgE skin-sensitizing antibodies in infected baboons.", "content": "Schistosoma mansoni: IgG and IgE skin-sensitizing antibodies in infected baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206930"} {"pmid": "4206931", "title": "Echinococcus granulosus: penetration of macromolecules and their localization on the parasite membranes of cysts.", "content": "Echinococcus granulosus: penetration of macromolecules and their localization on the parasite membranes of cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206931"} {"pmid": "4206933", "title": "Plasmodium cynomolgi: influence of x-irradiation and sporozoite dilution on relapse patterns in infected rhesus monkeys.", "content": "Plasmodium cynomolgi: influence of x-irradiation and sporozoite dilution on relapse patterns in infected rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206933"} {"pmid": "4206932", "title": "Effects of orally administered insecticides and polychlorinated biphenyls on the parasite fauna of two species of piscivorous birds.", "content": "Effects of orally administered insecticides and polychlorinated biphenyls on the parasite fauna of two species of piscivorous birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206932"} {"pmid": "4206924", "title": "Lung cancer.", "content": "Lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206924"} {"pmid": "4206934", "title": "Trypanosoma cruzi: possible stimulatory factor(s) on brown adipose tissue of mice.", "content": "Trypanosoma cruzi: possible stimulatory factor(s) on brown adipose tissue of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206934"} {"pmid": "4206935", "title": "Heligmosomoides polygrus (equals nematospiroides dubius): humoral and intestinal immunologic responses to infection in mice.", "content": "Heligmosomoides polygrus (equals nematospiroides dubius): humoral and intestinal immunologic responses to infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206935"} {"pmid": "4206921", "title": "Malignant melanoma: to biopsy or not to biopsy.", "content": "Malignant melanoma: to biopsy or not to biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206921"} {"pmid": "4206936", "title": "Schistosoma mansoni: effect of some cations on the proteolytic enzymes of cercariae.", "content": "Schistosoma mansoni: effect of some cations on the proteolytic enzymes of cercariae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206936"} {"pmid": "4206923", "title": "Diagnostic radiology for cancer.", "content": "Diagnostic radiology for cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206923"} {"pmid": "4206937", "title": "Complement fixation tests with cell culture fluid as antigen in comparison with cell culture neutralization tests in the identification of freshly isolated dengue virus: a pilot study.", "content": "Complement fixation tests with cell culture fluid as antigen in comparison with cell culture neutralization tests in the identification of freshly isolated dengue virus: a pilot study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206937"} {"pmid": "4206922", "title": "Classics in oncology. Sir Percivall Pott (1714-1788).", "content": "Classics in oncology. Sir Percivall Pott (1714-1788).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206922"} {"pmid": "4206938", "title": "A study of urethritis in males with particular reference to mycoplasma and TRIC-agent.", "content": "A study of urethritis in males with particular reference to mycoplasma and TRIC-agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206938"} {"pmid": "4206939", "title": "Solubilization of brain membrane proteins, polypeptide composition of fractions with different solubility characteristics.", "content": "Solubilization of brain membrane proteins, polypeptide composition of fractions with different solubility characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206939"} {"pmid": "4206940", "title": "Perinatal mortality and birthweight in Makassar, Indonesia.", "content": "Perinatal mortality and birthweight in Makassar, Indonesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206940"} {"pmid": "4206941", "title": "Early biochemical events occurring after infection of Bacillus cereus 569-SP1 with bacteriophage GSW.", "content": "Early biochemical events occurring after infection of Bacillus cereus 569-SP1 with bacteriophage GSW. After infection of Bacillus cereus 569-SP1 with the 5-hydroxymethyluracil-containing phage GSW, new dTTPase, dUTPase, and dUMP-hydroxymethylase activities appear. No significant changes in activities of other pyrimidine ribonucleoside or 2'-deoxyribonucleoside triphosphate nucleotidohydrolases were detected. dUTP and dUMP inhibit the dTTPase activity, whereas dTTP failed to inhibit dUTPase activity. The K(m) value for the substrate dUTP is 10(-4) M and for dTTP is 4.85 x 10(-4) M. Thymidylate synthetase activity is inhibited only when cells are infected during the late lag or very early log phases of growth; when cells are infected with phage during mid-log, thymidylate synthetase activity is unaffected. The data support the suggestion that, although phage GSW may inhibit an otherwise expected increase in activity of thymidylate synthetase, it fails to affect the already existing activity. The data presented do not allow discrimination as to whether the phage specifies inhibition of de novo synthesis of thymidylate synthetase or the increase in activity of already existing but not fully expressed enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206941"} {"pmid": "4206942", "title": "Abortive infection of lysogenic Bacillus subtilis 168(SPO2) by bacteriophage phi 1.", "content": "Abortive infection of lysogenic Bacillus subtilis 168(SPO2) by bacteriophage phi 1. Virulent bacteriophage phi1 was not able to productively infect strains of Bacillus subtilis which were lysogenic for the temperate bacteriophage SPO2, although it adsorbed to, penetrated, and killed these bacteria. Studies of phage and host nucleic acid production in the nonpermissive host demonstrated that normal phi1 transcription was initiated early in the latent period, but this was followed by a general failure of host and phage nucleic acid synthesis about 10 to 15 min after infection. Mixed infections of phi1 and SPO2c(1), a clear-plaque mutant of SPO2, indicated that a similar inhibition of phi1 development occurred when this phage infected nonlysogenic B. subtilis cells committed to the SPO2c(1) lytic cycle. It is proposed that the SPO2- and SPO2c(1)-mediated interference did not act directly on the phi1 genome, but rather these phages altered the host physiology in such a manner that some normal step in phi1 development triggered a collapse of vital metabolic activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206942"} {"pmid": "4206943", "title": "Bacteriophage interference in Bacillus subtilis 168.", "content": "Bacteriophage interference in Bacillus subtilis 168. Strains of Bacillus subtilis lysogenic for temperate bacteriophage SPO2 inhibit the development of bacteriophage phi1. After infection by bacteriophage phi1, DNA and RNA synthesis in the lysogenic host terminates, culminating in cell death. Bacteriophage SPO2 also prevents the production of bacteriophage phi105. Mechanisms for these two types of bacteriophage interference are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206943"} {"pmid": "4206944", "title": "Letter: Current management of gonorrhea.", "content": "Letter: Current management of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206944"} {"pmid": "4206945", "title": "Why residency programs in the military: the impact of history and influencing forces.", "content": "Why residency programs in the military: the impact of history and influencing forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206945"} {"pmid": "4206946", "title": "Acute mesenteric lymphadenitis due to Salmonella enteritidis mimicking appendicitis: case report.", "content": "Acute mesenteric lymphadenitis due to Salmonella enteritidis mimicking appendicitis: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206946"} {"pmid": "4206948", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206948"} {"pmid": "4206947", "title": "A review of 168 maxillo-facial fractures treated at Naval Hospital, Long Beach.", "content": "A review of 168 maxillo-facial fractures treated at Naval Hospital, Long Beach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206947"} {"pmid": "4206949", "title": "The outcome of 89 American and 224 Vietnamese sustaining brain wounds in Vietnam.", "content": "The outcome of 89 American and 224 Vietnamese sustaining brain wounds in Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206949"} {"pmid": "4206950", "title": "Immunological basis for the development of vaccines.", "content": "Immunological basis for the development of vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206950"} {"pmid": "4206951", "title": "Ventricular septal defects caused by stab wounds: report of two cases.", "content": "Ventricular septal defects caused by stab wounds: report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206951"} {"pmid": "4206952", "title": "Hyperemia and strokes: an evaluation of radioisotope findings.", "content": "Hyperemia and strokes: an evaluation of radioisotope findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206952"} {"pmid": "4206953", "title": "Simultaneous bilateral spontaneous pneumothorax.", "content": "Simultaneous bilateral spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206953"} {"pmid": "4206954", "title": "Blood preservation solutions. XI. Raising the pH to improve hemoglobin function.", "content": "Blood preservation solutions. XI. Raising the pH to improve hemoglobin function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206954"} {"pmid": "4206955", "title": "Significant research and future needs for improving patient care.", "content": "Significant research and future needs for improving patient care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206955"} {"pmid": "4206956", "title": "Complications of arterial puncture.", "content": "Complications of arterial puncture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206956"} {"pmid": "4206957", "title": "Distribution and prevalence of Bancroftian filariasis in US Army Special Forces Camps in the Republic of Vietnam.", "content": "Distribution and prevalence of Bancroftian filariasis in US Army Special Forces Camps in the Republic of Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206957"} {"pmid": "4206958", "title": "Sickle crisis precipitated by exercise rhabdomyolysis in a patient with sickle cell trait: case report.", "content": "Sickle crisis precipitated by exercise rhabdomyolysis in a patient with sickle cell trait: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206958"} {"pmid": "4206959", "title": "Military medicine and everybody's medicine.", "content": "Military medicine and everybody's medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206959"} {"pmid": "4206960", "title": "Editorial: Medicine at the crossroads.", "content": "Editorial: Medicine at the crossroads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206960"} {"pmid": "4206961", "title": "Introduction: Immunotherapy of cancer in man, a reality.", "content": "Introduction: Immunotherapy of cancer in man, a reality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206961"} {"pmid": "4206963", "title": "Transfer of steroidal hormones from blood to the cerebrospinal fluid in the Rhesus monkey.", "content": "Transfer of steroidal hormones from blood to the cerebrospinal fluid in the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206963"} {"pmid": "4206964", "title": "The effect of monoamine precursors on the release of growth hormone in the Rhesus monkey.", "content": "The effect of monoamine precursors on the release of growth hormone in the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206964"} {"pmid": "4206965", "title": "Contact between the mastitis laboratory and herd.", "content": "Contact between the mastitis laboratory and herd.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206965"} {"pmid": "4206966", "title": "Proctological admissions under a general surgeon.", "content": "Proctological admissions under a general surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206966"} {"pmid": "4206967", "title": "Radiological diagnosis.", "content": "Radiological diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206967"} {"pmid": "4206968", "title": "Management of bowel complications of radiotherapy.", "content": "Management of bowel complications of radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206968"} {"pmid": "4206969", "title": "Effects of long-term anticonvulsant therapy on calcium and vitamin D metabolism.", "content": "Effects of long-term anticonvulsant therapy on calcium and vitamin D metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206969"} {"pmid": "4206973", "title": "A study of the microbiological environment of the respiratory intensive care unit, the Royal Victoria Hospital.", "content": "A study of the microbiological environment of the respiratory intensive care unit, the Royal Victoria Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206973"} {"pmid": "4206974", "title": "The adsorption of Pseudomonas aeruginosa pilus-dependent bacteriophages to a host mutant with nonretractile pili.", "content": "The adsorption of Pseudomonas aeruginosa pilus-dependent bacteriophages to a host mutant with nonretractile pili.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206974"} {"pmid": "4206975", "title": "A spheroplast assay for recombination in bacteriophage lambda DNA.", "content": "A spheroplast assay for recombination in bacteriophage lambda DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206975"} {"pmid": "4206977", "title": "Trauma rounds: The role of hyperalimentation in patients with multiple injuries.", "content": "Trauma rounds: The role of hyperalimentation in patients with multiple injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206977"} {"pmid": "4206976", "title": "Purification and properties of Herpesvirus saimiri DNA.", "content": "Purification and properties of Herpesvirus saimiri DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206976"} {"pmid": "4206995", "title": "Stage 3 Hodgkin's disease: six years experience.", "content": "Stage 3 Hodgkin's disease: six years experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206995"} {"pmid": "4206996", "title": "Whole cell heat-killed gram-negative bacilli vaccine.", "content": "Whole cell heat-killed gram-negative bacilli vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206996"} {"pmid": "4206997", "title": "C. G. Kratzenstein professor physices experimentalis Petropol. et Havn. and his Studies on Electricity during the eighteenth century.", "content": "C. G. Kratzenstein professor physices experimentalis Petropol. et Havn. and his Studies on Electricity during the eighteenth century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206997"} {"pmid": "4206999", "title": "Carcinoma linguae. A series of 96 patients.", "content": "Carcinoma linguae. A series of 96 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4206999"} {"pmid": "4207000", "title": "The distribution of 198Au injected intravenously as a colloid and in solution.", "content": "The distribution of 198Au injected intravenously as a colloid and in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207000"} {"pmid": "4207001", "title": "Spectral distributions from 60Co therapy units.", "content": "Spectral distributions from 60Co therapy units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207001"} {"pmid": "4207002", "title": "Measurements of primary spectra from a kilocurie 60Co unit and a 6 MeV linear accelerator.", "content": "Measurements of primary spectra from a kilocurie 60Co unit and a 6 MeV linear accelerator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207002"} {"pmid": "4207003", "title": "Cervical pharyngostomy. A safe alternative for gastrointestinal decompression.", "content": "Cervical pharyngostomy. A safe alternative for gastrointestinal decompression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207003"} {"pmid": "4207004", "title": "Eschar: a major factor in postburn pneumonia.", "content": "Eschar: a major factor in postburn pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207004"} {"pmid": "4207005", "title": "High velocity missile injury. An experimental study of the retentive forces of tissue.", "content": "High velocity missile injury. An experimental study of the retentive forces of tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207005"} {"pmid": "4207007", "title": "Surgical intervention in acute necrotizing pancreatitis.", "content": "Surgical intervention in acute necrotizing pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207007"} {"pmid": "4207006", "title": "Use of chemically defined diets in the management of patients with acute inflammatory bowel disease.", "content": "Use of chemically defined diets in the management of patients with acute inflammatory bowel disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207006"} {"pmid": "4207008", "title": "Review of the toxicity of long-term phosgene exposure.", "content": "Review of the toxicity of long-term phosgene exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207008"} {"pmid": "4207009", "title": "Preparation of hair for lead analysis.", "content": "Preparation of hair for lead analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207009"} {"pmid": "4207010", "title": "Recurrent experimental allergic polyganglioradiculoneuritis. Multiple demyelinating episodes in rhesus monkey sensitized with rabbit sciatic nerve myelin.", "content": "Recurrent experimental allergic polyganglioradiculoneuritis. Multiple demyelinating episodes in rhesus monkey sensitized with rabbit sciatic nerve myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207010"} {"pmid": "4207011", "title": "Early traumatic epilepsy. Incidence and significance after nonmissile injuries.", "content": "Early traumatic epilepsy. Incidence and significance after nonmissile injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207011"} {"pmid": "4207012", "title": "Penetrating keratoplasty with use of through-and-through nylon sutures.", "content": "Penetrating keratoplasty with use of through-and-through nylon sutures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207012"} {"pmid": "4207013", "title": "Xenon photocoagulation and the retinal vasculature.", "content": "Xenon photocoagulation and the retinal vasculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207013"} {"pmid": "4207014", "title": "Treatment of nonspecific diarrhea in infants.", "content": "Treatment of nonspecific diarrhea in infants. A treatment schedule based on the thesis that failure to allow for mucosal regeneration contributes to the morbidity and mortality from nonspecific diarrhea in infancy is presented. This treatment approach has been found successful. In diarrhea, because a vicious cycle of intestinal hypermotility can be started regardless of the initial cause, the preferred course is to put the bowel at rest initially and allow the intestinal mucosa an opportunity to heal. With a dehydrated infant, parenteral fluids calculated to repair deficits in 24-48 hours are administered. Nothing is given by mouth during this initial period. It is believed that persisting with oral feedings often delays healing and prolongs the illness. Once the deficits have been corrected and the stool volume has decreased, the patient is offered small amounts of a glucose-electrolyte solution by mouth. The volume is gradually increased until the infant's maintenance requirement for water is met. Before starting milk feedings the glucose-electrolyte solution is continued for at least 24 hours. The formula initially administered is a 25% solution in a volume which fulfills fluid requirements. At 24-hour intervals, the concentration of the formula is increased. The patient is observed closely during the advancement. There is immediate return to the glucose-electrolyte solution if there should be an increase in stool number, volume or water content. A recurrence of diarrhea is often presaged by a fall in stool pH (below 6). A stool pH below 6 strongly suggests impaired carbohydrate absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207014"} {"pmid": "4207015", "title": "Effects of alpha-ecdysone, beta-ecdysone and inokosterone on the in vitro evagination of Drosophila leg discs and the subsequent differentiation of imaginal integumentary structures.", "content": "Effects of alpha-ecdysone, beta-ecdysone and inokosterone on the in vitro evagination of Drosophila leg discs and the subsequent differentiation of imaginal integumentary structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207015"} {"pmid": "4207017", "title": "Environmental regulation of enzymes in the microbodies and mitochondria of dark-grown, greening, and light-grown Euglena graclis.", "content": "Environmental regulation of enzymes in the microbodies and mitochondria of dark-grown, greening, and light-grown Euglena graclis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207017"} {"pmid": "4207016", "title": "Developmental changes of adenosine deaminase, xanthine oxidase, and uricase in mouse tissues.", "content": "Developmental changes of adenosine deaminase, xanthine oxidase, and uricase in mouse tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207016"} {"pmid": "4207018", "title": "Platelet and fibrinogen reactions in Pseudomonas aeruginosa exotoxin shock.", "content": "Platelet and fibrinogen reactions in Pseudomonas aeruginosa exotoxin shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207018"} {"pmid": "4207019", "title": "Brachial arteriovenous shunts for hemodialysis and extracorporeal procedures.", "content": "Brachial arteriovenous shunts for hemodialysis and extracorporeal procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207019"} {"pmid": "4207020", "title": "Influence of age and sex on serum copper and ceruloplasmin levels.", "content": "Influence of age and sex on serum copper and ceruloplasmin levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207020"} {"pmid": "4207021", "title": "A predictor for total body potassium in man based on height, weight, sex and age: applications in metabolic disorders.", "content": "A predictor for total body potassium in man based on height, weight, sex and age: applications in metabolic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207021"} {"pmid": "4207022", "title": "Gold kinetics following aurothiomalate therapy: use of a whole-body radiation counter.", "content": "Gold kinetics following aurothiomalate therapy: use of a whole-body radiation counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207022"} {"pmid": "4207026", "title": "Transfusion of neutrophils as prevention or treatment of infection in patients with neutropenia.", "content": "Transfusion of neutrophils as prevention or treatment of infection in patients with neutropenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207026"} {"pmid": "4207025", "title": "Calcitonin as a tumor marker. Use of the radioimmunoassay for calcitonin in the postoperative evaluation of patients with medullary thyroid carcinoma.", "content": "Calcitonin as a tumor marker. Use of the radioimmunoassay for calcitonin in the postoperative evaluation of patients with medullary thyroid carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207025"} {"pmid": "4207028", "title": "Effect of ascorbic acid on lipoprotein lipase activity.", "content": "Effect of ascorbic acid on lipoprotein lipase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207028"} {"pmid": "4207029", "title": "Cortical control of cell division.", "content": "Cortical control of cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207029"} {"pmid": "4207032", "title": "Effect of FSH on the in vitro uptake of 3H-testosterone by the cultured seminiferous tubule.", "content": "Effect of FSH on the in vitro uptake of 3H-testosterone by the cultured seminiferous tubule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207032"} {"pmid": "4207038", "title": "Maturation of fetal body systems. Report of a WHO scientific group.", "content": "Maturation of fetal body systems. Report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207038"} {"pmid": "4207039", "title": "Mycoplasma aetiology of keratoconjunctivitis (\"pink-eye\") in domestic ruminants.", "content": "Mycoplasma aetiology of keratoconjunctivitis (\"pink-eye\") in domestic ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207039"} {"pmid": "4207040", "title": "The role of the conceptus in plasma protein metabolism in the rat.", "content": "The role of the conceptus in plasma protein metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207040"} {"pmid": "4207041", "title": "The effect of corticosteroid on absorption and endogenous production of immunoglobulins in calves.", "content": "The effect of corticosteroid on absorption and endogenous production of immunoglobulins in calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207041"} {"pmid": "4207042", "title": "Proceedings: The influence of glucagon on regional blood flow in the rhesus monkey.", "content": "Proceedings: The influence of glucagon on regional blood flow in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207042"} {"pmid": "4207043", "title": "Proceedings: A technique for studying drug absorption from the lung in man.", "content": "Proceedings: A technique for studying drug absorption from the lung in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207043"} {"pmid": "4207044", "title": "Proceedings: Anti-nociceptive effects in N-substituted cyclohexylmethylbenzamides.", "content": "Proceedings: Anti-nociceptive effects in N-substituted cyclohexylmethylbenzamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207044"} {"pmid": "4207045", "title": "Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase.", "content": "Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. 1. DL-C-Allyglycine, 4-deoxypyridoxine hydrochloride and 3-mercaptopropionic acid have been studied with reference to their convulsant effects in mice and in baboons (Papio papio) with photosensitive epilepsy, and their action on the cerebral enzyme synthesizing gamma-aminobutyric acid (L-glutamate-1-carboxy-lyase).2. In mice, the ED(50) values for seizures following intraperitoneal injection were allylglycine 1.0 mmol/kg body weight, 4-deoxypyridoxine 1.1 mmol/kg and 3-mercaptopropionic acid 0.27 mmol/kg. Latency to seizure onset was longest after allylglycine (44-240 min), intermediate after 4-deoxypyridoxine (9-114 min) and shortest after 3-mercaptopropionic acid (2.5-8 min).3. In Papio papio intravenous administration of subconvulsant doses of allylglycine (0.87-3.1 mmol/kg), or of 4-deoxypyridoxine (0.21-0.53 mmol/kg) enhanced the occurrence and persistence of myoclonic responses to intermittent photic stimulation, and augmented the associated electroencephalographic abnormalities, without modifying their character or distribution. Higher doses produced brief seizures recurring at regular intervals, between 2-14 h after allylglycine (4.0-4.3 mmol/kg) or 1-4 h after 4-deoxypyridoxine (0.53-0.87 mmol/kg). Electroencephalographically these seizures originated unilaterally in the occipital or posterior parietal cortex.4. In Papio papio photically-induced epileptic responses were enhanced 5-10 min after the intravenous injection of 3-mercaptopropionic acid (0.09-0.28 mmol/kg). A sequence of brief generalized seizures followed by complete recovery occurred 4-17 min after the injection of 3-mercaptopropionic acid (0.28-0.38 mmol/kg). Fatal status epilepticus followed the injection of 3-mercaptopropionic acid (0.57-0.75 mmol/kg). E.E.G. records showed generalized cortical involvement at the onset of the seizures.5. L-Glutamate 1-carboxy-lyase (GAD) activity was determined in whole brain homogenates from mice killed at various intervals after receiving i.p. a convulsant dose of one of the compounds. Inhibition of GAD activity was evident 30-60 min before seizure onset following allylglycine or 4-deoxypyridoxine administration, and was maximal (40-60%) just before or during seizure activity. Addition of pyridoxal phosphate to the brain homogenate relieved inhibition produced by 4-deoxypyridoxine but not that produced by allylglycine. Inhibition of GAD activity in brain homogenates from animals killed 2 or 4 min after injection of a convulsant dose of 3-mercaptopropionic acid varied from 0-49% depending on the dose of 3-mercaptopropionic acid and the concentration of substrate in the assay system.6. Kinetic analysis of the inhibition of GAD activity following direct addition of the compounds to mouse brain homogenates indicated that 3-mercaptopropionic acid (0.01-0.5 mM) was competitive with respect to the substrate. A comparable percentage inhibition of GAD activity was obtained only with much higher concentrations of 4-deoxypyridoxne, i.e. 10-50 mM. Allylglycine in vitro was a very weak inhibitor of GAD activity.7. Three biochemically different mechanisms underlie the inhibition of cerebral GAD activity that precedes seizures induced by ailylglycine, 4-deoxypyridoxine and 3-mercaptopropionic acid. The data are consistent with a critical reduction in the rate of synthesis of gamma-aminobutyric acid being responsible for the onset of seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207045"} {"pmid": "4207047", "title": "Ganglioside changes in slow virus diseases: analyses of chimpanzee brains infected with kuru and Creutzfeldt-Jakob agents.", "content": "Ganglioside changes in slow virus diseases: analyses of chimpanzee brains infected with kuru and Creutzfeldt-Jakob agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207047"} {"pmid": "4207046", "title": "Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs.", "content": "Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. 1. Resting splenic venous outflow from anaesthetized dogs contains prostaglandin-like material: the concentration increases after intra-arterial injections of bradykinin into the spleen, and is abolished by treatment with indomethacin.2. Intra-arterial injections of bradykinin into the spleen of lightly anaesthetized dogs elicit a dose-dependent reflex increase in the blood pressure, which is reduced but not abolished by treatment with indomethacin.3. Addition of prostaglandin E(1) or E(2) either by injections or by infusions restores the reflex increase in the blood pressure due to bradykinin injections after indomethacin treatment.4. The sensitizing action of endogenously released prostaglandins at or near the afferent nerve endings is discussed.5. The analgesic activity of aspirin-like drugs is explained in terms of the removal of the sensitizing activity of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207046"} {"pmid": "4207048", "title": "Short latency jaw movement produced by low intensity intracortical microstimulation of the precentral face area in monkeys.", "content": "Short latency jaw movement produced by low intensity intracortical microstimulation of the precentral face area in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207048"} {"pmid": "4207049", "title": "The permeability to small ions of tight junctions between cerebral endothelial cells.", "content": "The permeability to small ions of tight junctions between cerebral endothelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207049"} {"pmid": "4207050", "title": "Behavioral consequences of selective subtotal ablations in the postcentral gyrus of Macaca mulatta.", "content": "Behavioral consequences of selective subtotal ablations in the postcentral gyrus of Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207050"} {"pmid": "4207051", "title": "Inhibition of lordosis behavior in ovariectomized guinea pigs by mesencephalic implants of progesterone.", "content": "Inhibition of lordosis behavior in ovariectomized guinea pigs by mesencephalic implants of progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207051"} {"pmid": "4207054", "title": "The growth of Mycobacterium leprae in snakes.", "content": "The growth of Mycobacterium leprae in snakes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207054"} {"pmid": "4207055", "title": "Cell electrophoresis of amphibian blastula and gastrula cells; the relationship of surface charge and morphogenetic movement.", "content": "Cell electrophoresis of amphibian blastula and gastrula cells; the relationship of surface charge and morphogenetic movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207055"} {"pmid": "4207056", "title": "DNA synthesis following gross alterations of the nucleocytoplasmic ratio in the ciliate Stentor coeruleus.", "content": "DNA synthesis following gross alterations of the nucleocytoplasmic ratio in the ciliate Stentor coeruleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207056"} {"pmid": "4207058", "title": "Radiation resistance of spores of Bacillus subtilis and B. stearothermophilus at various water activities.", "content": "Radiation resistance of spores of Bacillus subtilis and B. stearothermophilus at various water activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207058"} {"pmid": "4207059", "title": "Further studies with lipoamide dehydrogenase mutants of Escherichia coli K12.", "content": "Further studies with lipoamide dehydrogenase mutants of Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207059"} {"pmid": "4207060", "title": "In vitro protein synthesis and measurement of the stability of messenger RNA in the blue-green alga, anabaena variabilis.", "content": "In vitro protein synthesis and measurement of the stability of messenger RNA in the blue-green alga, anabaena variabilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207060"} {"pmid": "4207061", "title": "The spontaneous release of somatic antigen from Vibrio cholerae.", "content": "The spontaneous release of somatic antigen from Vibrio cholerae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207061"} {"pmid": "4207062", "title": "The mast cells of the mammalian central nervous system. 2. The effect of proton irradiation in the monkey.", "content": "The mast cells of the mammalian central nervous system. 2. The effect of proton irradiation in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207062"} {"pmid": "4207069", "title": "Some paediatric problems of Australian Aborigines.", "content": "Some paediatric problems of Australian Aborigines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207069"} {"pmid": "4207071", "title": "Conditioned behavior in Drosophila melanogaster.", "content": "Conditioned behavior in Drosophila melanogaster. Populations of Drosophila were trained by alternately exposing them to two odorants, one coupled with electric shock. On testing, the flies avoided the shock-associated odor. Pseudoconditioning, excitatory states, odor preference, sensitization, habituation, and subjective bias have been eliminated as explanations. The selective avoidance can be extinguished by retraining. All flies in the population have equal probability of expressing this behavior. Memory persists for 24 hr. Another paradigm has been developed in which flies learn to discriminate between light sources of different color.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207071"} {"pmid": "4207070", "title": "Mechanism of IgM polymerization.", "content": "Mechanism of IgM polymerization. The stoichiometry of J chain in pentamer IgM has been determined by measuring the radiolabeled thiols in the constituent chains after complete reduction and alkylation of the polymer. One mole of J was found to be disulfide bonded to 1 mol of pentamer. The linkage of J chain in IgM has been determined by correlating the J disulfides cleaved with the subunits released after limited reduction and alkylation of the polymer. The analyses showed that: (a) Significant amounts of monomers, as well as small quantities of dimers, trimers, and tetramers, were generated by the reducing conditions employed. (b) The number of J disulfide bonds broken did not correspond to the extent of depolymerization. (c) No J disulfides were cleaved in the J-containing dimer products of the limited reduction. These data demonstrated that the J chain is located as a disulfide clasp between two of the IgM monomer subunits. From the observed linkage, the assembly of IgM is postulated to proceed by a series of sequential disulfide exchanges beginning with the formation of the J-containing dimer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207070"} {"pmid": "4207073", "title": "Induction of nucleolar and mitochondrial DNA replication in Tetrahymena pyriformis.", "content": "Induction of nucleolar and mitochondrial DNA replication in Tetrahymena pyriformis. Selective induction of replication of nucleolar and mitochondrial DNA has been demonstrated in starved-refed cultures of Tetrahymena pyriformis by different techniques. Labeling of starved cells with [(3)H]thymidine during a nutritional shift-up and analysis of the DNA in isopycnic CsCl gradients shows that the two initially labeled species of DNA are two species banding on the heavy and light side of the bulk macronuclear DNA. In isolated macronuclei the radioactivity is found only in the high density fraction, which has been shown to be of nucleolar origin. In sucrose gradients the newly replicated mitochondrial and nucleolar DNAs sediment considerably slower than the bulk DNA, as one discrete band corresponding to a molecular weight of about 3 to 4 x 10(7). Electron microscope autoradiography of cells labeled with [(3)H]thymidine as above shows that the peripheral nucleoli of the macronucleus as well as the mitochondria are labeled before any radioactivity is found in the chromatin granules of the macronucleus. The results clearly indicate that nucleolar and mitochondrial DNA replication are under a control independent of that for the replication of bulk DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207073"} {"pmid": "4207072", "title": "Control of translation in cultured cells: continued synthesis and accumulation of messenger RNA in nondividing cultures.", "content": "Control of translation in cultured cells: continued synthesis and accumulation of messenger RNA in nondividing cultures. Nontransformed animal fibroblasts in tissue culture regulate total protein and ribosomal RNA synthesis coordinately with changes in the cellular growth state. Here it is shown that the amounts and rates of synthesis of cytoplasmic poly(A)-containing RNA, presumed to be mRNA, do not appreciably change with alterations in growth state. In nongrowing (resting) cultures of BALB/c 3T3 cells presumptive mRNA molecules predominantly accumulate as cytoplasmic ribonucleoprotein particles; the RNA from which can be chased into the polyribosomal structure upon activation of the resting cultures with animal sera. It is suggested that the decreased protein synthetic rate in resting as compared with growing cells is in part due to a failure of preexisting mRNAs to attach to ribosomes and that addition of serum to the tissue culture medium can partially overcome this translational lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207072"} {"pmid": "4207074", "title": "Prostaglandin F in moneky uterine fluid during the menstrual cycle and following steroid treatment.", "content": "Prostaglandin F in moneky uterine fluid during the menstrual cycle and following steroid treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207074"} {"pmid": "4207076", "title": "The family practitioner and the juvenile diabetic.", "content": "The family practitioner and the juvenile diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207076"} {"pmid": "4207078", "title": "Levels of plasma immunoglobulins in Malaysians.", "content": "Levels of plasma immunoglobulins in Malaysians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207078"} {"pmid": "4207077", "title": "The rationale for the use of drugs in the treatment of diabetes mellitus.", "content": "The rationale for the use of drugs in the treatment of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207077"} {"pmid": "4207079", "title": "Alteration of the liver blood flow and phagocytic activity of the reticuloendothelial system in monkeys infected with Plasmodium knowlesi.", "content": "Alteration of the liver blood flow and phagocytic activity of the reticuloendothelial system in monkeys infected with Plasmodium knowlesi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207079"} {"pmid": "4207080", "title": "Accidental human infection with Plasmodium cynomolgi bastianellii.", "content": "Accidental human infection with Plasmodium cynomolgi bastianellii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207080"} {"pmid": "4207081", "title": "Studies on the erythrophagocytosis in rhesus monkeys infected with Plasmodium knowlesi.", "content": "Studies on the erythrophagocytosis in rhesus monkeys infected with Plasmodium knowlesi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207081"} {"pmid": "4207082", "title": "The association of neoplastic diseases and mycotoxins in the environment.", "content": "The association of neoplastic diseases and mycotoxins in the environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207082"} {"pmid": "4207083", "title": "The effect of Travase on wound healing.", "content": "The effect of Travase on wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207083"} {"pmid": "4207084", "title": "Interference with organogenesis and fetal development.", "content": "Interference with organogenesis and fetal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207084"} {"pmid": "4207085", "title": "Human coumarin prothrombin. Chromatographic, coagulation and immunologic studies.", "content": "Human coumarin prothrombin. Chromatographic, coagulation and immunologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207085"} {"pmid": "4207086", "title": "Platelet factor 3 activity in washed platelets.", "content": "Platelet factor 3 activity in washed platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207086"} {"pmid": "4207087", "title": "Platelets and clot retraction. Effect of divalent cations and several drugs.", "content": "Platelets and clot retraction. Effect of divalent cations and several drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207087"} {"pmid": "4207099", "title": "The cephalic arterial system in insectivores, primates, rodents and lagomorphs, with special reference to the systematic classification.", "content": "The cephalic arterial system in insectivores, primates, rodents and lagomorphs, with special reference to the systematic classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207099"} {"pmid": "4207101", "title": "Carbamate resistance in Musca domestica nebulo.", "content": "Carbamate resistance in Musca domestica nebulo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207101"} {"pmid": "4207100", "title": "Prostaglandins--basic and clinical considerations.", "content": "Prostaglandins--basic and clinical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207100"} {"pmid": "4207103", "title": "A comparison of the life cycles of Toxoplasma and Hepatozoon, with reference to the general phenomenon and the role of cyst formation in the Coccidia.", "content": "A comparison of the life cycles of Toxoplasma and Hepatozoon, with reference to the general phenomenon and the role of cyst formation in the Coccidia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207103"} {"pmid": "4207106", "title": "A double-blind trial of long-term lithium therapy in mental defectives.", "content": "A double-blind trial of long-term lithium therapy in mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207106"} {"pmid": "4207109", "title": "Uptake of the yolk protein, lipovitellin, by developing crustacean oocytes.", "content": "Uptake of the yolk protein, lipovitellin, by developing crustacean oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207109"} {"pmid": "4207108", "title": "The toxicity of polychlorinated polycyclic compounds and related chemicals.", "content": "The toxicity of polychlorinated polycyclic compounds and related chemicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207108"} {"pmid": "4207110", "title": "Effects and interactions of juvenile hormone and beta-ecdysone on Drosophila imaginal discs cultured in vitro.", "content": "Effects and interactions of juvenile hormone and beta-ecdysone on Drosophila imaginal discs cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207110"} {"pmid": "4207111", "title": "Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. I. Dependence upon ecdysone concentration.", "content": "Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. I. Dependence upon ecdysone concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207111"} {"pmid": "4207112", "title": "Dependence of transdetermination frequency on the developmental stage of cultured imaginal discs of Drosophila melanogaster.", "content": "Dependence of transdetermination frequency on the developmental stage of cultured imaginal discs of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207112"} {"pmid": "4207115", "title": "Intracistronic mapping of electrophoretic sites in Drosophila melanogaster: fidelity of information transfer by gene conversion.", "content": "Intracistronic mapping of electrophoretic sites in Drosophila melanogaster: fidelity of information transfer by gene conversion. A convenient method is described for the intracistronic mapping of genetic sites responsible for electrophoretic variation of a specific protein in Drosophila melanogaster. A number of wild-type isoalleles of the rosy locus have been isolated which are associated with the production of electrophoretically distinguishable xanthine dehydrogenases. Large-scale recombination experiments were carried out involving null enzyme mutants induced on electrophoretically distinct wild-type isoalleles, the genetic basis for which is followed as a nonselective marker in the cross. Additionally, a large-scale recombination experiment was carried out involving null enzyme rosy mutants induced on the same wild-type isoallele. Examination of the electrophoretic character of crossover and convertant products recovered from the latter experiment revealed that all exhibited the same parental electrophoretic character. In addition to documenting the stability of the xanthine dehydrogenase electrophoretic character, this observation argues against a special mutagenesis hypothesis to explain conversions resulting from allele recombination studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207115"} {"pmid": "4207116", "title": "The genetic structure of natural populations of Drosophila melanogaster. XI. Genetic variability in a local population.", "content": "The genetic structure of natural populations of Drosophila melanogaster. XI. Genetic variability in a local population. Six hundred and ninety-one second chromosomes were extracted from a Raleigh, North Carolina population, and the following experimental results were obtained: (1) Salivary gland chromosomes of all lines were observed and the number of inversion-carrying chromosomes was 130, among which 76 carried In(2R)NS, 36 carried In(2L)t, 4 carried In(2L)t and In(2R)NS, and 14 carried different kinds of rare inversions. (2) Viabilities of homozygotes and heterozygotes were examined. The frequency of lethal-carrying chromosomes was 275/691 (or 0.398):70/130 (or 0.538) in inversion-carrying chromosomes and 205/561 (or 0.365) in inversion-free chromosomes. The former is significantly higher than the latter. The average homozygote viability was 0.4342 including lethal lines and 0.7163 excluding those, the average heterozygote viability being 1.0000. The detrimental load to lethal load ratio (D:L ratio) was 0.334/0.501 = 0.67. The average viability of lethal heterozygotes was less than that of lethal-free heterozygotes, significantly in inversion-free individuals but not significantly so in inversion-carrying individuals. Inversion heterozygotes seem to have slightly better viability than the inversion-free heterozygotes on the average, but not significantly so. (3) The average degree of dominance of viability polygenes was estimated to be 0.293 +/- 0.071 for all heterozygotes whose component chromosomes had better viabilities than 0.6 of the average heterozygote viability, 0.177 +/- 0.077 for inversion-free heterozygotes and 0.489 +/- 0.082 for inversion heterozygotes. (4) Mutation rates of viability polygenes and lethal genes were estimated on the basis of genetic loads and average degrees of dominance of lethal genes and viability polygenes. Estimates were very close to those obtained by direct estimation. (5) Possible overdominance and epistasis were detected, but the magnitude must be very small. (6) The effective size of the population was estimated to be much greater than 10,000 by using the allelism rate of lethal-carrying chromosomes (0.0040) and their frequency.-On the basis of these findings and the comparison with the predicted result (Mukai and Maruyama 1971), the mechanisms of the maintenance of genetic variability in the population are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207116"} {"pmid": "4207118", "title": "Induction of sexual reproduction in Opalina sudafricana by injecting its host Bufo regularis with gibberellic acid.", "content": "Induction of sexual reproduction in Opalina sudafricana by injecting its host Bufo regularis with gibberellic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207118"} {"pmid": "4207117", "title": "An ultrastructural study of the response of Blatella germanica (Orthoptera: Blattidae) to the nematode Abbreviata caucasica (Spirurida: Physalopteridae).", "content": "An ultrastructural study of the response of Blatella germanica (Orthoptera: Blattidae) to the nematode Abbreviata caucasica (Spirurida: Physalopteridae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207117"} {"pmid": "4207119", "title": "Duration and specificity of sodium cromolyn on allergen inhalation challenges in asthmatics.", "content": "Duration and specificity of sodium cromolyn on allergen inhalation challenges in asthmatics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207119"} {"pmid": "4207121", "title": "Kinetics of cross-linking of peptidoglycan in Bacillus megaterium.", "content": "Kinetics of cross-linking of peptidoglycan in Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207121"} {"pmid": "4207120", "title": "Human carbonic anhydrases. XII. The complete primary structure of the C isozyme.", "content": "Human carbonic anhydrases. XII. The complete primary structure of the C isozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207120"} {"pmid": "4207122", "title": "Purification and properties of L-lysine monooxygenase from Pseudomonas fluorescens.", "content": "Purification and properties of L-lysine monooxygenase from Pseudomonas fluorescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207122"} {"pmid": "4207123", "title": "Regulatory properties of the flavoprotein L-lysine monooxygenase.", "content": "Regulatory properties of the flavoprotein L-lysine monooxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207123"} {"pmid": "4207124", "title": "Vascularization and the gliding mechanism of free flexor-tendon grafts inserted by the silicone-rod method.", "content": "Vascularization and the gliding mechanism of free flexor-tendon grafts inserted by the silicone-rod method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207124"} {"pmid": "4207125", "title": "Steinmann-pin fixation in the treatment of unstable fractures of the ankle.", "content": "Steinmann-pin fixation in the treatment of unstable fractures of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207125"} {"pmid": "4207126", "title": "Effect of tolbutamide on the metabolism of Tetrahymena.", "content": "Effect of tolbutamide on the metabolism of Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207126"} {"pmid": "4207127", "title": "The mammalian pars intermedia: a review of its structure and function.", "content": "The mammalian pars intermedia: a review of its structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207127"} {"pmid": "4207128", "title": "Blood-group-like substances in some marine invertebrates. 3. Glycoproteins with blood-group A specificity in the cephalopods Sepia officinalis L. and Loligo vulgaris Lam.", "content": "Blood-group-like substances in some marine invertebrates. 3. Glycoproteins with blood-group A specificity in the cephalopods Sepia officinalis L. and Loligo vulgaris Lam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207128"} {"pmid": "4207129", "title": "Functional organization of a visual area in the posterior bank of the superior temporal sulcus of the rhesus monkey.", "content": "Functional organization of a visual area in the posterior bank of the superior temporal sulcus of the rhesus monkey. 1. Anatomical studies have shown the cortex of the posterior bank of the superior temporal sulcus to receive a projection from visual cortical areas, including areas 17, 18 and 19. In this paper the response of single neurones in this area to simple visual stimulation is reported. Ten monkeys were studied.2. A clear but relatively crude topographic representation of the visual field was found. There was a large variation in the size of the receptive fields of individual cells, even in a single penetration. Some cells, with the central parts of their receptive fields located from between 1 and 5 degrees from the centre of gaze had receptive fields averaging about 10 degrees x 10 degrees or even larger. Other cells with central receptive fields had much smaller field sizes.3. Two main types of neurones were encountered, with subdivisions within each type. The first type responded to movement irrespective of form. These could be subdivided into neurones which responded to movement in any direction within the receptive field and neurones which responded to movement in one direction only (directionally selective neurones). Another type of cell was responsive to both contour and movement, much like the complex and lower order hypercomplex cells. Almost all such neurones were directionally selective.4. In oblique penetrations through this cortical region, there tended frequently to be an orderly shift in preferred directions of motion, thus suggesting the possibility of a columnar organization for movement.5. Combined anatomical (degeneration) and electrophysiological experiments showed that these types of neurones are found in those regions of the posterior bank of the superior temporal sulcus receiving a direct projection from area 17.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207129"} {"pmid": "4207131", "title": "The effect of sodium and calcium ions on the release of catecholamines from the adrenal medulla: sodium deprivation induces release by exocytosis in the absence of extracellular calcium.", "content": "The effect of sodium and calcium ions on the release of catecholamines from the adrenal medulla: sodium deprivation induces release by exocytosis in the absence of extracellular calcium. 1. Perfusing bovine adrenal glands with Na(+)-free Locke solution for 15-40 min did not modify the increase in the release of catecholamines from glands stimulated by acetylcholine. However, after 80-100 min of perfusion with Na(+)-free solution, the response to acetylcholine stimulation was decreased or abolished.2. Immediately after switching the perfusion medium to Na(+)-free solution, there was a sharp increase (6-10 times over control values) in catecholamine output.3. Graded substitution of Na(+) in the perfusion fluid enhanced the output of catecholamines. This increase in the output of amines was linearly related to the logarithm of the extracellular Na(+) concentration.4. The release of catecholamines in the absence of Na(+) was not reduced by the presence of atropine and hexamethonium nor by the omission of Ca(2+) in the presence of EDTA or EGTA.5. Excess of Mg(2+) in the perfusion fluid reduced (10 mM-Mg(2+)) or blocked (20 mM-Mg(2+)) the increase in the output of catecholamines induced by Na(+) deprivation in the presence or absence of extracellular Ca(2+).6. Na(+) deprivation induced release of catecholamines during perfusion of the glands with depolarizing concentrations (56 mM) of K(+).7. In the presence or the absence of extracellular Ca(2+), the increase in the output of catecholamines induced by Na(+) deprivation was accompanied by an increase in the output of dopamine beta-hydroxylase, but not of lactate dehydrogenase. In addition, during perfusion with Ca(2+) free solution, Na(+) deprivation induced a parallel increase in both catecholamine and adenosine triphosphate outputs.8. The ratios of catecholamines to dopamine beta-hydroxylase and catecholamines to adenosine triphosphate determined in the perfusates collected from glands during perfusion with Na(+)-free medium were similar to those measured in the soluble contents of isolated chromaffin granules. These results provided biochemical evidence in favour of exocytosis as the mechanism of secretion during Na(+) deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207131"} {"pmid": "4207130", "title": "Ionic mechanism for the photoreceptor potential of the retina of Bufo marinus.", "content": "Ionic mechanism for the photoreceptor potential of the retina of Bufo marinus. 1. Membrane potentials were recorded from single rods in the isolated retina of Bufo marinus while the ionic composition of the extracellular medium was rapidly changed. Substitution of 2 mM aspartate(-) for Cl(-) produced a prompt depolarization of horizontal cells, but no modification of either resting potential or response to light in receptor cells. This implies that feed-back from horizontal cells to receptor cells was not active.2. During substitution of choline(+) or Li(+) for Na(+), and during isosmotic substitution of sucrose for NaCl, the resting potential of receptor cells became more negative and responses to light were abolished. During exposure to K(+)-free medium, the resting potential became slightly more negative and the responses to light became larger and developed small after-depolarizations. Exposure to [K(+)](out) of four times normal resulted in permanent diminution of response magnitude and permanent change of response waveshape. Removal of Mg(2+), four times normal [Mg(2+)](out) or substitution of methylsulphate(-) for Cl(-) had no effect on resting potential or responses to light. With the exception of the small effects seen with altered [K(+)](out) these results are consistent with the receptor potential being generated by a light-induced decrease of membrane conductance to Na(+).3. Exposure to decreased [Ca(2+)](out) caused both a depolarization of the receptor membrane in the dark and an increase in the magnitude of the maximal response that could be evoked by a test stimulus. The magnitude of the increase in response equalled the magnitude of the depolarization. Exposure to increased [Ca(2+)](out) or steady background light caused both a steady hyperpolarization and a decrease in the magnitude of the maximal response that could be evoked by a test stimulus. For steady hyperpolarizations greater than 3.5 mV, whether caused by elevated [Ca(2+)](out) or steady background light, the decrease in response magnitude exceeded the magnitude of the hyperpolarization. These results imply that externally applied Ca(2+) ions mimic the effects of steady background lights, but the applied Ca(2+) ions must do more than merely decrease membrane conductance to Na(+).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207130"} {"pmid": "4207132", "title": "Tuberculosis in a family day-care home. Report of an outbreak and recommendations for prevention.", "content": "Tuberculosis in a family day-care home. Report of an outbreak and recommendations for prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207132"} {"pmid": "4207133", "title": "Gonococcal colony types.", "content": "Gonococcal colony types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207133"} {"pmid": "4207134", "title": "Editorial: The nondiscriminant gonococcus.", "content": "Editorial: The nondiscriminant gonococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207134"} {"pmid": "4207135", "title": "Infective endocarditis. A review of selected topics.", "content": "Infective endocarditis. A review of selected topics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207135"} {"pmid": "4207136", "title": "Bacteremia caused by gram-negative bacilli.", "content": "Bacteremia caused by gram-negative bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207136"} {"pmid": "4207140", "title": "Amniotic fluid assay as an index for gestational age and fetal development in the baboon.", "content": "Amniotic fluid assay as an index for gestational age and fetal development in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207140"} {"pmid": "4207141", "title": "Ultrasonic aspiration transducer for management of Rh incompatibility.", "content": "Ultrasonic aspiration transducer for management of Rh incompatibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207141"} {"pmid": "4207142", "title": "A dose-rate effect in the ultraviolet inactivation of bacterial spores.", "content": "A dose-rate effect in the ultraviolet inactivation of bacterial spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207142"} {"pmid": "4207145", "title": "Comparative investigations on several immunodiffusion methods for Australia antigen detection. II. Electroimmunodiffusion.", "content": "Comparative investigations on several immunodiffusion methods for Australia antigen detection. II. Electroimmunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207145"} {"pmid": "4207146", "title": "Studies on the sensitivity of a passive hemagglutination test in the detection of antimeasles antibodies.", "content": "Studies on the sensitivity of a passive hemagglutination test in the detection of antimeasles antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207146"} {"pmid": "4207147", "title": "Investigations on human antibodies against Australia antigen.", "content": "Investigations on human antibodies against Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207147"} {"pmid": "4207148", "title": "Letter: False positive reactions in the electroimmunodiffusion technique for Australia antigen detection.", "content": "Letter: False positive reactions in the electroimmunodiffusion technique for Australia antigen detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207148"} {"pmid": "4207149", "title": "Immunochemical study of the interaction between staphylococcal protein A, rabbit antistaphylococcal sera, and selected sera from nonimmunized animals.", "content": "Immunochemical study of the interaction between staphylococcal protein A, rabbit antistaphylococcal sera, and selected sera from nonimmunized animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207149"} {"pmid": "4207150", "title": "Immunoglobulins in feces from infants fed human or bovine milk.", "content": "Immunoglobulins in feces from infants fed human or bovine milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207150"} {"pmid": "4207151", "title": "On the frequency of valine in position 2 of the V k3 subgroup.", "content": "On the frequency of valine in position 2 of the V k3 subgroup.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207151"} {"pmid": "4207152", "title": "The principle of immunopotentiation in treatment of rheumatoid arthritis: effect of transfer factor.", "content": "The principle of immunopotentiation in treatment of rheumatoid arthritis: effect of transfer factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207152"} {"pmid": "4207153", "title": "Summary of recent abstracts. VII. Rickettsial diseases.", "content": "Summary of recent abstracts. VII. Rickettsial diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207153"} {"pmid": "4207155", "title": "Intestinal cystoplasty. Long-term functional result.", "content": "Intestinal cystoplasty. Long-term functional result.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207155"} {"pmid": "4207154", "title": "Ureteral duplication and prostatic disease.", "content": "Ureteral duplication and prostatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207154"} {"pmid": "4207156", "title": "Diverticula of female urethra. Diagnostic importance of postvoiding film.", "content": "Diverticula of female urethra. Diagnostic importance of postvoiding film.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207156"} {"pmid": "4207157", "title": "Condyloma acuminatum of male urethra. Successful management with 5-fluorouracil.", "content": "Condyloma acuminatum of male urethra. Successful management with 5-fluorouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207157"} {"pmid": "4207158", "title": "Enhancement of microsomal drug hydroxylation and glucuronidation in rat liver by phenobarbital and 3-methylcholanthrene in combination.", "content": "Enhancement of microsomal drug hydroxylation and glucuronidation in rat liver by phenobarbital and 3-methylcholanthrene in combination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207158"} {"pmid": "4207160", "title": "Water movement in the vitreous body, evaluated experimentally and theoretically.", "content": "Water movement in the vitreous body, evaluated experimentally and theoretically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207160"} {"pmid": "4207159", "title": "Activation and inactivation of membrane-bound UDP-glucuronosyltransferase by organic solvents in vitro.", "content": "Activation and inactivation of membrane-bound UDP-glucuronosyltransferase by organic solvents in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207159"} {"pmid": "4207161", "title": "Placental transfer of a cephalosporin derivative (C 36'278-Ba).", "content": "Placental transfer of a cephalosporin derivative (C 36'278-Ba).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207161"} {"pmid": "4207162", "title": "Bacteriostatic action of middle ear exudate and blood leucocytes.", "content": "Bacteriostatic action of middle ear exudate and blood leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207162"} {"pmid": "4207163", "title": "Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen.", "content": "Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207163"} {"pmid": "4207164", "title": "Concerning the role of zinc in the antitumor activity of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazonato) zinc(II) and related chelates.", "content": "Concerning the role of zinc in the antitumor activity of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazonato) zinc(II) and related chelates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207164"} {"pmid": "4207172", "title": "Effects of concentration of volatile metabolites from bacteria and germinating seeds on fungi in the presence of selective absorbents.", "content": "Effects of concentration of volatile metabolites from bacteria and germinating seeds on fungi in the presence of selective absorbents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207172"} {"pmid": "4207173", "title": "Immunological response of guinea pigs experimentally infected with Histoplasma duboisii.", "content": "Immunological response of guinea pigs experimentally infected with Histoplasma duboisii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207173"} {"pmid": "4207174", "title": "Dimension control in bacteria.", "content": "Dimension control in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207174"} {"pmid": "4207175", "title": "The isolation of blue-green bacteria in pure culture.", "content": "The isolation of blue-green bacteria in pure culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207175"} {"pmid": "4207177", "title": "Cystic fibrosis: synthesis of ciliary inhibitor by amniotic cells.", "content": "Cystic fibrosis: synthesis of ciliary inhibitor by amniotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207177"} {"pmid": "4207176", "title": "Sympathetic and parasympathetic components of reflex tachycardia induced by hypotension in conscious dogs with and without heart failure.", "content": "Sympathetic and parasympathetic components of reflex tachycardia induced by hypotension in conscious dogs with and without heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207176"} {"pmid": "4207178", "title": "The genetics of hereditary angioedema: a hypothesis.", "content": "The genetics of hereditary angioedema: a hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207178"} {"pmid": "4207179", "title": "An analysis of the development program in relation to RNA metabolism in the ciliate Stylonychia mytilus.", "content": "An analysis of the development program in relation to RNA metabolism in the ciliate Stylonychia mytilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207179"} {"pmid": "4207180", "title": "Development of the temperature-sensitive homoeotic mutant ophthalmoptera of Drosophila melanogaster.", "content": "Development of the temperature-sensitive homoeotic mutant ophthalmoptera of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207180"} {"pmid": "4207181", "title": "Development of early behaviors in neonatal squirrel monkeys and cotton-top tamarins.", "content": "Development of early behaviors in neonatal squirrel monkeys and cotton-top tamarins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207181"} {"pmid": "4207184", "title": "Enhancing factor on anti-hapten antibody response released from PPDs-stimulated tubercle bacilli-sensitized cells.", "content": "Enhancing factor on anti-hapten antibody response released from PPDs-stimulated tubercle bacilli-sensitized cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207184"} {"pmid": "4207185", "title": "Purification and properties of the C4 inactivator from nurse shark serum.", "content": "Purification and properties of the C4 inactivator from nurse shark serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207185"} {"pmid": "4207186", "title": "Structural features of pig IgA.", "content": "Structural features of pig IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207186"} {"pmid": "4207187", "title": "Two new inhibitory activities in blood of mice with delayed hypersensitivity, after challenge with specific antigen.", "content": "Two new inhibitory activities in blood of mice with delayed hypersensitivity, after challenge with specific antigen. In addition to the activities associated with migration inhibitory factor and type II interferon, two other inhibitory activities have been found in the sera of mice infected intravenously with BCG and 3 weeks later challenged intravenously with old tuberculin. Growth of three bacteria, Streptococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, and one yeast, Candida albicans, was inhibited in vitro by a factor or factors in the serum. Also, hematopoiesis of mouse bone marrow cells in a soft agar medium was suppressed by the serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207187"} {"pmid": "4207188", "title": "Detection of nonspecific resistance to Listeria monocytogenes in rabbits infected with Treponema pallidum.", "content": "Detection of nonspecific resistance to Listeria monocytogenes in rabbits infected with Treponema pallidum. Several lines of evidence suggest that cell-mediated immunity (CMI) is suppressed in the early stages of infection caused by Treponema pallidum and becomes activated at the time that latency is induced. In the studies reported in this paper, rabbits were infected intravenously with T. pallidum and subsequently challenged with Listeria monocytogenes. Enhanced ability to suppress the growth of Listeria was detected in their livers between 3 and 5 weeks after infection with T. pallidum, corresponding to the onset and regression of the generalized syphilitic eruption. A second infection of T. pallidum 4 weeks after the first, at a time when suppression was beginning to wane, prolonged the listericidal activity. These observations support the hypothesis that infection by T. pallidum stimulates CMI, which, in turn, may play a role in inducing latency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207188"} {"pmid": "4207190", "title": "Occurrence of quinovosamine in lipopolysaccharides of Brucella species.", "content": "Occurrence of quinovosamine in lipopolysaccharides of Brucella species. Lipopolysaccharides obtained from Brucella abortus, B. melitensis, and B. suis, but not B. canis, were found to contain amino sugars identified as glucosamine and quinovosamine by cation exchange and thin-layer cellulose chromatography and ninhydrin degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207190"} {"pmid": "4207189", "title": "Respiratory immune response to aerosolized keyhole limpet hemocyanin in primate lungs.", "content": "Respiratory immune response to aerosolized keyhole limpet hemocyanin in primate lungs. Methodology for delivery of antigen to the lower respiratory tract of rhesus monkeys and the recovery of respiratory secretions (RS) by bronchial lavage has been evaluated and has been done on repeated occasions without apparent risk to animals. Rhesus immunoglobulin (Ig)G, IgM, and IgA were identified in RS by their cross-reactivity with human IgG, IgA, and IgM, and relative concentrations of rhesus IgA and IgG could be evaluated in sequential samples of RS and serum (S) by radial immunodiffusion analysis using antiserum specific for human gamma and alpha chains. Administration of keyhole limpet hemocyanin (KLH) by aerosol was compared with intravenous administration of KLH. The aerosol route of administration resulted in IgG, IgM, and IgA antibodies detectable by radio-immunodiffusion in RS but only IgG antibodies in serum. After separate sequences of exposure to KLH delivered to the lung, a secondary type of immune response in the lung appeared as indicated by time of appearance and height of antibody titers. Antibody titers against KLH were estimated by passive hemagglutination of tanned sheep red cells coated with KLH, and anti-KLH titers were comparatively higher in RS of animals immunized by the respiratory route. Treatment of RS and S with 2-mercaptoethanol resulted in reduction of hemagglutination titers of both S and RS, but the degree of reduction varied in different samples and was independent of whether or not the S and RS were collected simultaneously. These results indicate that at least part of the antibody response to aerosolized KLH in rhesus monkeys occurs in the lung and that antibodies may appear in all three immunoglobulin classes in this response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207189"} {"pmid": "4207191", "title": "Replication of macronuclear DNA in the cytoplasm of Tetrahymena pyriformis.", "content": "Replication of macronuclear DNA in the cytoplasm of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207191"} {"pmid": "4207192", "title": "Observations implicating an extracellular enzymic mechanism of control of bone morphogenesis.", "content": "Observations implicating an extracellular enzymic mechanism of control of bone morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207192"} {"pmid": "4207193", "title": "Distribution of peroxidase activity in Tetrahymena pyriformis mitochondria.", "content": "Distribution of peroxidase activity in Tetrahymena pyriformis mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207193"} {"pmid": "4207194", "title": "Giant lysosomes in cultured monkey kidney cells.", "content": "Giant lysosomes in cultured monkey kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207194"} {"pmid": "4207195", "title": "Immunochemistry of counterimmunoelectrophoresis and the effect of electroendosmotic flow on reactivity.", "content": "Immunochemistry of counterimmunoelectrophoresis and the effect of electroendosmotic flow on reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207195"} {"pmid": "4207196", "title": "Spontaneous rosettes as a T-lymphocyte marker: a modified method giving consistent results. SRBC rosettes.", "content": "Spontaneous rosettes as a T-lymphocyte marker: a modified method giving consistent results. SRBC rosettes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207196"} {"pmid": "4207197", "title": "Detection and quantitation of chicken antibodies to streptococcal carbohydrate by high-salt reverse radial immunodiffusion.", "content": "Detection and quantitation of chicken antibodies to streptococcal carbohydrate by high-salt reverse radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207197"} {"pmid": "4207198", "title": "Heterogeneity of RNA polymerase in Escherichia coli. I. A new holoenzyme containing a new sigma factor.", "content": "Heterogeneity of RNA polymerase in Escherichia coli. I. A new holoenzyme containing a new sigma factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207198"} {"pmid": "4207199", "title": "Blood levels of free and bound thyroid hormones.", "content": "Blood levels of free and bound thyroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207199"} {"pmid": "4207200", "title": "On earlier states of the biochemical system.", "content": "On earlier states of the biochemical system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207200"} {"pmid": "4207201", "title": "Antagonism of ethanol narcosis by thyrotropin releasing hormone.", "content": "Antagonism of ethanol narcosis by thyrotropin releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207201"} {"pmid": "4207202", "title": "Cytoplasmic factors in the gonads of Culex pipiens complex mosquitoes.", "content": "Cytoplasmic factors in the gonads of Culex pipiens complex mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207202"} {"pmid": "4207205", "title": "The significance of brucella antibodies in patients in a rural area.", "content": "The significance of brucella antibodies in patients in a rural area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207205"} {"pmid": "4207206", "title": "Evaluation of systemic steroid treatment in children with asthma.", "content": "Evaluation of systemic steroid treatment in children with asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207206"} {"pmid": "4207204", "title": "Transfection of Bacillus subtilis with bacteriophage H1 DNA: fate of transfecting DNA and transfection enhancement in B. subtilis uur+ and uur- strains.", "content": "Transfection of Bacillus subtilis with bacteriophage H1 DNA: fate of transfecting DNA and transfection enhancement in B. subtilis uur+ and uur- strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207204"} {"pmid": "4207207", "title": "Renal blood flow and function following suprarenal ligation of the inferior caval vein. An experimental study in the rabbit.", "content": "Renal blood flow and function following suprarenal ligation of the inferior caval vein. An experimental study in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207207"} {"pmid": "4207208", "title": "An anthrax outbreak in Berkshire.", "content": "An anthrax outbreak in Berkshire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207208"} {"pmid": "4207213", "title": "Interaction between azotobacter chroococcum, bacillus megaterium var. phosphaticum and rhizobium sp.", "content": "Interaction between azotobacter chroococcum, bacillus megaterium var. phosphaticum and rhizobium sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207213"} {"pmid": "4207216", "title": "The effect of certain nitro-herbicides on the growth of some soil-inhabiting fungi.", "content": "The effect of certain nitro-herbicides on the growth of some soil-inhabiting fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207216"} {"pmid": "4207217", "title": "An apparatus for the microslide immunodiffusion.", "content": "An apparatus for the microslide immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207217"} {"pmid": "4207218", "title": "Intracortical distribution of renal blood flow during saline infusion in dogs.", "content": "Intracortical distribution of renal blood flow during saline infusion in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207218"} {"pmid": "4207219", "title": "Influence of aldosterone on active sodium transport by the toad bladder: a kinetic approach.", "content": "Influence of aldosterone on active sodium transport by the toad bladder: a kinetic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207219"} {"pmid": "4207220", "title": "Primate biliary physiology. IX. Effects of acute biliary obstruction on biliary lipid metabolism in the monkey.", "content": "Primate biliary physiology. IX. Effects of acute biliary obstruction on biliary lipid metabolism in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207220"} {"pmid": "4207221", "title": "Kinetics of kinin release in canine plasma.", "content": "Kinetics of kinin release in canine plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207221"} {"pmid": "4207222", "title": "Nitroglycerin and chromonar on small-vessel blood content of the ventricular walls.", "content": "Nitroglycerin and chromonar on small-vessel blood content of the ventricular walls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207222"} {"pmid": "4207224", "title": "Changes in the subunit structure of Bacillus subtilis RNA polymerase during sporulation.", "content": "Changes in the subunit structure of Bacillus subtilis RNA polymerase during sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207224"} {"pmid": "4207225", "title": "Transcriptional systems in eukaryotic cells.", "content": "Transcriptional systems in eukaryotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207225"} {"pmid": "4207226", "title": "The stringent response--21 years on.", "content": "The stringent response--21 years on.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207226"} {"pmid": "4207229", "title": "New concepts in the management of mycosis fungoides.", "content": "New concepts in the management of mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207229"} {"pmid": "4207228", "title": "A dermatosis specifically associated with a tumour of pancreatic alpha cells.", "content": "A dermatosis specifically associated with a tumour of pancreatic alpha cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207228"} {"pmid": "4207230", "title": "The use of the hamster stomach in vitro as an assay preparation for prostaglandins.", "content": "The use of the hamster stomach in vitro as an assay preparation for prostaglandins. 1. Hamster stomach strips in vitro are useful test preparations for the assay of prostaglandins E and F in the nanogram concentration range. Three-minute cycles can be used for long periods without spontaneous contractions or significant base-line instability.2. The mean percentage error and the precision index of six 4-point assays of prostaglandin E(2) were 7.8 and 0.057, respectively.3. The relative sensitivity to different prostaglandins was E(2)/E(1) approximately 1, E(2)/F(1alpha) approximately 65 and E(2)/A(1) approximately 400.4. These preparations were relatively insensitive to 5-hydroxytryptamine (prostaglandin E(2)/5-HT approximately 20,000) and histamine (prostaglandin E(2)/histamine approximately 200).5. These results suggest that the hamster stomach preparation can be used to differentiate between 5-hydroxytryptamine and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207230"} {"pmid": "4207232", "title": "Response of flocculus Purkinje cells to adequate vestibular stimulation in the alert monkey: fixation vs. compensatory eye movements.", "content": "Response of flocculus Purkinje cells to adequate vestibular stimulation in the alert monkey: fixation vs. compensatory eye movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207232"} {"pmid": "4207231", "title": "A kallikrein-like substance in cat nasal secretion.", "content": "A kallikrein-like substance in cat nasal secretion. Incubation of cat nasal secretion with cat plasma releases a substance which will contract the cat isolated jejunum, a tissue specifically sensitive to bradykinin and similar peptides. The smooth muscle stimulating activity of the incubate is potentiated and prolonged 'by the addition of the kininase inhiibitor, EDTA. From the results it is concluded that the incubation of cat nasal secretion and plasma releases a kinin-like substance, and that this kinin may have a role in the secretory and vasomotor activity of the nasal mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207231"} {"pmid": "4207233", "title": "Editorial: Diagnosis of thyroid diseases.", "content": "Editorial: Diagnosis of thyroid diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207233"} {"pmid": "4207234", "title": "Therapeutic efficacy of rifampin in newly detected pulmonary tuberculosis.", "content": "Therapeutic efficacy of rifampin in newly detected pulmonary tuberculosis. A comparison was made of the therapeutic efficiency and tolerance of rifampin-based regimens and that of the standard triple-drug combination in the treatment of 92 newly diagnosed cases of pulmonary tuberculosis. The three drug regimens investigated were: A, rifampin-INH; B, rifampin-INH-streptomycin; and C, INH-PAS-streptomycin. Therapeutic progress was measured in terms of sputum conversion on culture and microscopy. The rifampin combinations produced a somewhat earlier sputum conversion. With regimens containing this potent antibiotic the phenomenon of microscopically-positive but culture-negative specimens was more frequently observed. The tolerance exhibited to the rifampin regimens was far greater than that to the conventional triple-drug combination. Nevertheless, periodic laboratory examinations are essential during rifampin therapy for safe utilization of the drug. An incidental finding of this study was the increase in primary resistance to streptomycin particularly among recent immigrants to Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207234"} {"pmid": "4207235", "title": "Thymidine metabolism during normal and compensatory renal growth.", "content": "Thymidine metabolism during normal and compensatory renal growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207235"} {"pmid": "4207236", "title": "Corynebacterium, tubercle bacillus and cancer.", "content": "Corynebacterium, tubercle bacillus and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207236"} {"pmid": "4207237", "title": "Retinal synaptogenesis in the primate.", "content": "Retinal synaptogenesis in the primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207237"} {"pmid": "4207238", "title": "The inhibitory effect of pentobarbital Na on aqueous humor formation.", "content": "The inhibitory effect of pentobarbital Na on aqueous humor formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207238"} {"pmid": "4207239", "title": "Chromatographic and biological aspects of DDT and its metabolites.", "content": "Chromatographic and biological aspects of DDT and its metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207239"} {"pmid": "4207240", "title": "Effects of microquantities of testosterone on the epididymis and accessory glands of the castrated rhesus monkey, Macaca mulatta.", "content": "Effects of microquantities of testosterone on the epididymis and accessory glands of the castrated rhesus monkey, Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207240"} {"pmid": "4207241", "title": "Behavioral activities and cardiovascular functions: effects of hexamethonium on cardiovascular changes during strong sustained static work in rhesus monkeys.", "content": "Behavioral activities and cardiovascular functions: effects of hexamethonium on cardiovascular changes during strong sustained static work in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207241"} {"pmid": "4207242", "title": "The role of the autonomic nervous system in the responses of the perfused canine paw to prostaglandins B1 and B2.", "content": "The role of the autonomic nervous system in the responses of the perfused canine paw to prostaglandins B1 and B2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207242"} {"pmid": "4207243", "title": "Prevention of acute pulmonary insufficiency by eriodictyol.", "content": "Prevention of acute pulmonary insufficiency by eriodictyol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207243"} {"pmid": "4207244", "title": "The effect of acetazolamide and furosemide on cerebrospinal fluid production and choroid plexus carbonic anhydrase activity.", "content": "The effect of acetazolamide and furosemide on cerebrospinal fluid production and choroid plexus carbonic anhydrase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207244"} {"pmid": "4207245", "title": "Morphine metabolism in vivo and in vitro by homozygous Gunn rats.", "content": "Morphine metabolism in vivo and in vitro by homozygous Gunn rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207245"} {"pmid": "4207246", "title": "Evaluation of the crypt surface adjacent to metal endosseous implants: an electron microscopic study in clinically successful implants.", "content": "Evaluation of the crypt surface adjacent to metal endosseous implants: an electron microscopic study in clinically successful implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207246"} {"pmid": "4207247", "title": "Protease-sensitive transfection of Bacillus subtilis with bacteriophage GA-1 DNA: a probable case of heterologous transfection.", "content": "Protease-sensitive transfection of Bacillus subtilis with bacteriophage GA-1 DNA: a probable case of heterologous transfection. The host bacterium of bacteriophage GA-1, Bacillus sp. G1R, was compared with respect to its taxonomic relationship to Bacillus subtilis, B. licheniformis, and B. pumilis. The physiological-biochemical properties of Bacillus sp. G1R are equal to those of B. licheniformis, but the thermal denaturation midpoint of G1R DNA differs by 3 C and the buoyant density by 0.005 g/cm(3) from that of B. licheniformis. Transformation with G1R donor DNA was neither observed in B. licheniformis nor in B. subtilis-competent recipients. Bacteriophage GA-1 shows neither infectivity on B. licheniformis nor on B. subtilis. However, infection of competent B. subtilis cultures with phenol-extracted GA-1 DNA results in the production of infective GA-1 particles. The transfecting activity of GA-1 DNA is destroyed by treatment with proteolytic enzymes. Resistance of transfecting DNA to inactivation by trypsin develops earlier than that to inactivation by DNase. Protease-treated GA-1 DNA competes with transforming DNA to approximately the same extent as does untreated GA-1 DNA, suggesting that uptake of GA-1 DNA is not affected by protease treatment. CsCl density gradient centrifugation reveals that the density of trypsinized GA-1 DNA is 0.004 g/cm(3) greater than that of untreated DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207247"} {"pmid": "4207249", "title": "Psychomotor epilepsy in childhood.", "content": "Psychomotor epilepsy in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207249"} {"pmid": "4207250", "title": "Diagnosis and treatment of childhood myoclonic seizures.", "content": "Diagnosis and treatment of childhood myoclonic seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207250"} {"pmid": "4207255", "title": "Plasma transferrin in Singapore women during pregnancy.", "content": "Plasma transferrin in Singapore women during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207255"} {"pmid": "4207256", "title": "The role of infection on wound healing.", "content": "The role of infection on wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207256"} {"pmid": "4207257", "title": "Dicephalus, spina bifida, Arnold-Chiari malformation and duplication of thoracic organs in a calf. Description of the case and critical discussion of the pathogenesis of the Arnold-Chiari malformation.", "content": "Dicephalus, spina bifida, Arnold-Chiari malformation and duplication of thoracic organs in a calf. Description of the case and critical discussion of the pathogenesis of the Arnold-Chiari malformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207257"} {"pmid": "4207258", "title": "Blood and milk levels of chloramphenicol in normal and mastitic cows and ewes after intramuscular administration of chloramphenicol and chloramphenicol sodium succinate.", "content": "Blood and milk levels of chloramphenicol in normal and mastitic cows and ewes after intramuscular administration of chloramphenicol and chloramphenicol sodium succinate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207258"} {"pmid": "4207261", "title": "Multiple myeloma of IgA type in a dog.", "content": "Multiple myeloma of IgA type in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207261"} {"pmid": "4207262", "title": "Prenatal development and activity of the thyroid gland of the buffalo.", "content": "Prenatal development and activity of the thyroid gland of the buffalo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207262"} {"pmid": "4207263", "title": "Diabetes mellitus with pancreatic atrophy in antelopes in the Amsterdam zoo.", "content": "Diabetes mellitus with pancreatic atrophy in antelopes in the Amsterdam zoo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207263"} {"pmid": "4207264", "title": "N-bromosuccinimide protects chick embryos against the lathyrogenic effect of isonicotinic acid hydrazide.", "content": "N-bromosuccinimide protects chick embryos against the lathyrogenic effect of isonicotinic acid hydrazide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207264"} {"pmid": "4207266", "title": "Experimental iris sutures in the monkey.", "content": "Experimental iris sutures in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207266"} {"pmid": "4207267", "title": "Puerperal morbidity and internal fetal monitoring.", "content": "Puerperal morbidity and internal fetal monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207267"} {"pmid": "4207268", "title": "Placental transfer and distribution of nicotine in the pregnant rhesus monkey.", "content": "Placental transfer and distribution of nicotine in the pregnant rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207268"} {"pmid": "4207269", "title": "Venous thrombosis on prosthetic surfaces. Evolution and blood coagulation studies in a nonhuman primate model.", "content": "Venous thrombosis on prosthetic surfaces. Evolution and blood coagulation studies in a nonhuman primate model. Thrombi deposited on prosthetic devices in the superior vena cava of the rhesus monkey were studied by morphologic and biochemical technics. Glass or silicone-coated glass (SCG) rings were implanted for 30 minutes to 14 days. Thrombus was deposited on the surface of each prosthetic device, and deposition was much greater and more rapid on glass surfaces than on SCG surfaces. On SCG surfaces, initial deposits consisting of single platelets, small platelet aggregates and erythrocytes were seen by scanning electron microscopy. These were followed by larger platelet aggregates, fibrin and, much later, leukocytes. Transmission electron micrographs revealed disintegration of the platelets forming aggregates and an osmiophilic deposit on the prosthetic surface. Shortened partial thromboplastin times were observed in all test animals but the sham-operated one, and therefore may be predictive of thrombus formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207269"} {"pmid": "4207272", "title": "Mycobacterial skin tests in humans 12 years after infection with Mycobacterium marinum.", "content": "Mycobacterial skin tests in humans 12 years after infection with Mycobacterium marinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207272"} {"pmid": "4207271", "title": "Pulmonary intravascular leukocyte sequestration. A potential mechanism of lung injury.", "content": "Pulmonary intravascular leukocyte sequestration. A potential mechanism of lung injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207271"} {"pmid": "4207270", "title": "Pancreatic beta cell replication induced by glucocorticoids in subhuman primates.", "content": "Pancreatic beta cell replication induced by glucocorticoids in subhuman primates. Pancreatic islets were studied by means of light microsocpy, autoradiography and electron microscopy in untreated Macaca cyclopis monkeys and after the administration of large quantities of adrenal glucocorticoids. Mild hyperglycemia and profound elevations of serum immunoreactive insulin were induced by glucocorticoid injections of 1 to 3 weeks duration, with a gradual return to pretreatment levels within 2 months after cessation of treatment. Morphologic alterations included degranulation and hyperplasia of pancreatic beta cells. These were noted in association with increased numbers of labeled islet cells after the administration of (3)H-thymidine and beta cells undergoing mitotic division, and could be correlated directly with the magnitude of serum insulin elevation. Evidence of acinar-islet or duct-islet cell transformation was absent. Beta cell regranulation and the twofold increase in extractable pancreatic insulin which followed the cessation of injections demonstrated the survival and functional integrity of the newly formed beta cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207270"} {"pmid": "4207273", "title": "Ethambutol-isoniazid versus streptomycin-ethambutol-isoniazid in original treatment of cavitary tuberculosis.", "content": "Ethambutol-isoniazid versus streptomycin-ethambutol-isoniazid in original treatment of cavitary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207273"} {"pmid": "4207274", "title": "Letter: Urethral burning as a side effect of cromolyn sodium.", "content": "Letter: Urethral burning as a side effect of cromolyn sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207274"} {"pmid": "4207275", "title": "Skeletal reactions to neoplasms.", "content": "Skeletal reactions to neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207275"} {"pmid": "4207276", "title": "Small-sample blood culture method for identification of bacteria in central arterial and peripheral blood.", "content": "Small-sample blood culture method for identification of bacteria in central arterial and peripheral blood. A blood culture technique that utilized small arterial blood samples or peripheral capillary blood was tested in beagle dogs and pig-tailed macaque monkeys. A bolus of 2.0 x 10(7)Escherichia coli (ATCC 25922) was injected intravenously into five animals of each species. Blood samples were taken before injection of the organisms and 10, 15, 20, 30, 60, and 120 min after injection. Arterial blood samples (2.0 and 0.2 ml) and peripheral capillary samples (0.14 ml) were taken at each sampling time. Pour plates were prepared from arterial blood for colony counts. All three blood sampling methods were equally effective in detecting sepsis when 10 or more organisms per ml of blood were present. Below this level, the 2.0-ml sample was more effective. Contamination of the peripheral sample with air or skin contaminants was a problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207276"} {"pmid": "4207277", "title": "New gas chromatographic characterization procedure: preliminary studies on some Pseudomonas species.", "content": "New gas chromatographic characterization procedure: preliminary studies on some Pseudomonas species. Strains of saccharolytic and nonsaccharolytic Pseudomonas species were examined by a new single-step gas chromatographic characterization procedure. Cells were digested in a methanolic solution of tetramethylammonium hydroxide pentahydrate, and the digestates were subjected to gas-liquid chromatographic analysis. The chromatograms were examined for similarities and differences in their overall patterns. A single component was defined for use as an internal qualitative and quantitative standardizing component in order to develop relative retention time-relative peak height profiles of each organism. Comparison of these profiles enabled the characterization of strains of Pseudomonas aeruginosa, P. putida, P. cepacia, P. pseudomallei, P. stutzeri, P. pseudoalcaligenes, P. alcaligenes, P. diminuta, P. denitrificans, and P. acidovorans. The P. maltophilia and P. putrefaciens digestates showed chromatograms which were superficially similar yet easily distinguished as belonging to different species. The chromatograms of these two organisms were very different from those of other pseudomonads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207277"} {"pmid": "4207278", "title": "Polygalacturonate lyase production by Bacillus subtilis and Flavobacterium pectinovorum.", "content": "Polygalacturonate lyase production by Bacillus subtilis and Flavobacterium pectinovorum. Nutritional factors relating to the production of polygalacturonate lyases by strains of Bacillus subtilis and Flavobacterium pectinovorum were examined. Studies were carried out in shake flask cultures. In the case of B. subtilis the enzyme was produced constitutively, whereas in the case of F. pectinovorum it was only produced in quantity in the presence of pectic substances. Glucose was the most suitable carbon source for production of the polygalacturonate lyase of B. subtilis; of the nitrogen sources examined, the highest activities per milliliter of supernatant and per milligram of cells were obtained with glutamine and ammonium sulfate, respectively. The pattern of enzyme production and growth was similar although enzyme production ceased at pH 5.3. Sodium polypectate was the best inducer of polygalacturonate lyase with F. pectinovorum. Highest activity per milliliter of cell-free supernatant was obtained with skin milk powder as nitrogen source, although ammonium sulfate gave highest enzyme production per unit of biomass. Growth of F. pectinovorum occurred between pH 5.7 and 7.2. Enzyme production occurred during active growth and was independent of the pH of the medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207278"} {"pmid": "4207279", "title": "Stable mycoplasma antigen preparations for indirect hemagglutination tests.", "content": "Stable mycoplasma antigen preparations for indirect hemagglutination tests. In immunological studies of mycoplasmas, the use of glutaraldehyde for the fixative makes it possible to use erythrocytes from commercially available defibrinated sheep blood. It eliminates the necessity of having to screen blood from individual sheep to obtain a suitable source of erythrocytes, as when employing tannic acid for fixation and sensitization. The chemical bonding of soluble mycoplasma proteins to glutaraladehyde-fixed sheep erythrocytes by bis-diazotized 3,3'dimethoxy derivative, benzidine, yields preparations that are satisfactory antigens for performing the indirect hemagglutination test by the microtiter technique. The antigenic preparations are satisfactory for use after storage at 4 or -10 C for many months. Incorporation of 5% glycerine in the final suspending milieu makes it possible to obtain uniform suspensions of the fixed and sensitized sheep erythrocytes after freezing and after repeated freezing and thawing. Proteins from Mycoplasma arthritidis and M. hominis have been coupled to glutaraldehyde-fixed erythrocytes by diazotization. The last mentioned preparation detected the presence of antibodies in titers greater than 1:10 in 37% of 237 pregnant women whose ages ranged between 20 and 30 years. There was no correlation between the presence of specific antibodies in the blood and the isolation of M. hominis from the cervical canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207279"} {"pmid": "4207280", "title": "Slide agglutination method for the serological identification of Neisseria gonorrhoeae with anti-gonococcal antibodies adsorbed to protein A-containing staphylococci.", "content": "Slide agglutination method for the serological identification of Neisseria gonorrhoeae with anti-gonococcal antibodies adsorbed to protein A-containing staphylococci. A rapid slide agglutination test has been developed for the identification of Neisseria gonorrhoeae that are primarily detected as oxidase-positive colonies in gonococcal cultures. The technique is based on the specific nonimmune reactivity between the Fc portion of immunoglobulin (Ig)G and staphylococcal protein A. IgG molecules adsorbed to stabilized staphylococci will thereby become oriented with their antigen-reactive sites that are directed outwards. Protein A-containing staphylococci with unabsorbed anti-gonococcal antibodies gave positive co-agglutination reactions with gonococci but also with meningococci, some Moraxella, Haemophilus, and Pseudomonas strains. These crossreactions were eliminated by absorption of the anti-gonococcal antiserum with meningococcal and Moraxella organisms prior to the coating of reagent staphylococci. In the routine culture diagnosis of N. gonorrhoeae the use of specific gonococcal reagent staphylococci gave concordant results with fermentation procedures and immunofluorescent techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207280"} {"pmid": "4207281", "title": "Inhibition of aflatoxin production and tentative identification of an aflatoxin intermediate \"versiconal acetate\" from treatment with dichlorvos.", "content": "Inhibition of aflatoxin production and tentative identification of an aflatoxin intermediate \"versiconal acetate\" from treatment with dichlorvos. In general, aflatoxin production by Aspergillus flavus and A. parasiticus was greatly reduced in vitro in the presence of the insecticide dichlorvos. Reduction in yield of the toxins was accompanied by the apperance of a previously unidentified orange pigment. Spectral analyses of the pigment and of its methylated and acetylated derivatives indicated the compound to be versiconal acetate (IV). The data suggest that IV is an intermediate in the metabolic cycle that may terminate in the production of aflatoxin or of the versicolorins, or both. Dichlorvos apparently inhibits biosynthesis of the difurano ring structure common to the aflatoxins and the versicolorins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207281"} {"pmid": "4207283", "title": "Simplified sugar fermentation plate technique for identification of Neisseria gonorrhoeae.", "content": "Simplified sugar fermentation plate technique for identification of Neisseria gonorrhoeae. A simplified sugar fermentation technique incorporating (i) a glucose and (ii) a maltose, lactose, and sucrose plate was developed for confirming large numbers of Neisseria gonorrhoeae cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207283"} {"pmid": "4207282", "title": "Pyocin typing of Pseudomonas aeruginosa: a simplified method.", "content": "Pyocin typing of Pseudomonas aeruginosa: a simplified method. A simplified method has been devised for typing Pseudomonas aeruginosa by pyocin production. Pyocins are produced as strains grow overnight in Trypticase soy broth (without glucose) plus 1% potassium nitrate. Because P. aeruginosa can use nitrate instead of oxygen as a terminal electron acceptor, mechanical shaking is not necessary, nor is induction by mitomycin C. Pyocins can now be produced in screw-cap tubes in a water bath or incubator. A total of 250 strains were tested as possible pyocin indicators, which included 60 strains already used in pyocin-typing systems. The final set contained 18 indicators which were chosen because (i) they had clear positive or clear negative reactions, thus eliminating reactions difficult to read, (ii) they had few zones due to bacteriophage lysis, and (iii) they were most sensitive in differentiating clinical isolates of P. aeruginosa. The final typing method was tested in several studies and the results were clear; thus definitive epidemiological conclusions could be made. Because it is simple to perform and easily automated, the new method should have application in many hospitals; however, it should be used only in carefully planned epidemiological studies. The method and its application are described in detail, and some pitfalls are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207282"} {"pmid": "4207285", "title": "Serological characterization of buffalopox virus.", "content": "Serological characterization of buffalopox virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207285"} {"pmid": "4207284", "title": "Carrier cultures of human fetal diploid cells infected with coxsackievirus type B2.", "content": "Carrier cultures of human fetal diploid cells infected with coxsackievirus type B2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207284"} {"pmid": "4207286", "title": "Maturation of chloroplast rRNA in Euglena gracilis.", "content": "Maturation of chloroplast rRNA in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207286"} {"pmid": "4207287", "title": "A rotor speed dependent crossover in sedimentation velocities of DNA's of different sizes.", "content": "A rotor speed dependent crossover in sedimentation velocities of DNA's of different sizes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207287"} {"pmid": "4207288", "title": "The synthesis of MS 1 and MS 2 by Bacillus subtilis.", "content": "The synthesis of MS 1 and MS 2 by Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207288"} {"pmid": "4207289", "title": "Hepatic DNA repair synthesis in rats fed 3'-methyl-4-dimethylaminoazobenzene.", "content": "Hepatic DNA repair synthesis in rats fed 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207289"} {"pmid": "4207290", "title": "Studies on the fluorophore sempervirene and its complexes with DNA.", "content": "Studies on the fluorophore sempervirene and its complexes with DNA. Evidence that the fluorophore sempervirene binds to nucleic acids is presented. The complexes were studied by fluorescence intensity, spectra, decay lifetime, and polarization methods. Both fluorescent and nonfluorescent complexes are formed. The sempervirene is rigidly fixed to DNA. If ethidium bromide and sempervirene are bound to DNA, energy can be transferred from sempervirene to ethidium. Sempervirene is taken up by mammalian cells and appears in the cytoplasm. This unusual new probe should be useful in molecular and cellular investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207290"} {"pmid": "4207291", "title": "The influence of anaesthetics on the increase in the water permeability of the toad bladder induced by vasopressin.", "content": "The influence of anaesthetics on the increase in the water permeability of the toad bladder induced by vasopressin. 1 Single lobes of the bladder of Bufo marinus were isolated and filled with, and suspended in, oxygenated Ringer solution. The fluid in contact with the outside (serosa) of the lobes had a total osmolarity of 225 m-osmol/litre, and that bathing the inside (mucosa) of 45 m-osmol/litre.2 Osmotic water flow from mucosa to serosa was measured by weighing the lobes every 30 minutes. It was negligible unless vasopressin was added to the serosal bath. Standard concentrations of either 1.25 or 6.25 mu/ml were used to render the bladder lobes permeable to water.3 The presence in the serosal medium of pentobarbitone or thiopentone in concentrations ranging from 0.25 to 2.5 mM, or of chloralose in concentrations ranging from 0.65 to 6.5 mM, diminished the increase in water permeability induced by vasopressin.4 The three anaesthetics exerted similar inhibitory effects on the action of vasopressin from the serosal and from the mucosal surface of the bladder.5 In the presence of a constant high concentration of anaesthetic, increasing the concentration of vasopressin over three orders of magnitude led to stepwise increases of osmotic water flow out of the lobes, although at every dose level the effect of vasopressin was depressed by the anaesthetic. However, it was not completely abolished even if the concentration of vasopressin was close to threshold.6 The increase in water permeability of the bladder induced by 3',5'-adenosine monophosphate (cyclic AMP) was also depressed by the three anaesthetics.7 Possible explanations of the findings are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207291"} {"pmid": "4207292", "title": "The actions of prostaglandins E2 and F2alpha on human foetal intestine.", "content": "The actions of prostaglandins E2 and F2alpha on human foetal intestine. Human foetal small and large intestine responded to prostaglandins E(2) and F(2alpha), the gestational age of the tissue being between 14 and 26 weeks. The predominant response to both prostaglandins was a contraction of each region of the intestine studied. The response to both prostaglandins was antagonized selectively by poly.phloretin phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207292"} {"pmid": "4207294", "title": "Sensitivity to irradiation of the brain stem. Irradiation myelitis in the treatment of a nasopharynx carcinoma.", "content": "Sensitivity to irradiation of the brain stem. Irradiation myelitis in the treatment of a nasopharynx carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207294"} {"pmid": "4207293", "title": "Treatment of supraglottic cancer by radical high dose radiotherapy.", "content": "Treatment of supraglottic cancer by radical high dose radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207293"} {"pmid": "4207296", "title": "Restoration of fertility in sterilized Drosophila eggs by transplantation of polar cytoplasm.", "content": "Restoration of fertility in sterilized Drosophila eggs by transplantation of polar cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207296"} {"pmid": "4207295", "title": "Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. II. Osseous and fibro-osseous lesions, including osteoma, fibrous dysplasia, ossifying fibroma, osteoblastoma, giant cell tumor, and osteosarcoma.", "content": "Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. II. Osseous and fibro-osseous lesions, including osteoma, fibrous dysplasia, ossifying fibroma, osteoblastoma, giant cell tumor, and osteosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207295"} {"pmid": "4207297", "title": "Repair of a genetically-caused defect in oogenesis in Drosophila melanogaster by transplantation of cytoplasm from wild-type eggs and by injection of pyrimidine nucleosides.", "content": "Repair of a genetically-caused defect in oogenesis in Drosophila melanogaster by transplantation of cytoplasm from wild-type eggs and by injection of pyrimidine nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207297"} {"pmid": "4207299", "title": "Sources and disposition of pituitary prolactin in maternal circulation, amniotic fluid, fetus and placenta in the pregnant rhesus monkey.", "content": "Sources and disposition of pituitary prolactin in maternal circulation, amniotic fluid, fetus and placenta in the pregnant rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207299"} {"pmid": "4207298", "title": "Ovulating-inducing activity of FSH in the rat.", "content": "Ovulating-inducing activity of FSH in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207298"} {"pmid": "4207300", "title": "The pineal gland: a supplemental source of hypothalamic-releasing hormones.", "content": "The pineal gland: a supplemental source of hypothalamic-releasing hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207300"} {"pmid": "4207301", "title": "Interaction between thymic hormone and hypophyseal growth hormone on production of precipitating antibodies in the rat.", "content": "Interaction between thymic hormone and hypophyseal growth hormone on production of precipitating antibodies in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207301"} {"pmid": "4207302", "title": "Transmission of kuru and Creutzfeldt-Jakob disease to marmoset monkeys.", "content": "Transmission of kuru and Creutzfeldt-Jakob disease to marmoset monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207302"} {"pmid": "4207305", "title": "Ticarcillin, a new semisynthetic penicillin active on Pseudomonas aeruginosa: in vitro activity and blood levels in man.", "content": "Ticarcillin, a new semisynthetic penicillin active on Pseudomonas aeruginosa: in vitro activity and blood levels in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207305"} {"pmid": "4207306", "title": "Adhesion of Vi antigen and toxicity in typhoid vaccines inactivated by acetone or by heat and phenol.", "content": "Adhesion of Vi antigen and toxicity in typhoid vaccines inactivated by acetone or by heat and phenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207306"} {"pmid": "4207307", "title": "Immunological investigations of meningococcal disease. II. Some characteristics of group C antigen of Neisseria meningitidis in the sera of patients with fulminant meningococcemia.", "content": "Immunological investigations of meningococcal disease. II. Some characteristics of group C antigen of Neisseria meningitidis in the sera of patients with fulminant meningococcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207307"} {"pmid": "4207308", "title": "Course of experimental scrapie virus infection in the goat.", "content": "Course of experimental scrapie virus infection in the goat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207308"} {"pmid": "4207310", "title": "Demonstration of Neisseria gonorrhoeae with fluorescent antibody in patients with disseminated gonococcal infection.", "content": "Demonstration of Neisseria gonorrhoeae with fluorescent antibody in patients with disseminated gonococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207310"} {"pmid": "4207309", "title": "Epidemic disease due to serogroup C Neisseria meningitidis in Saõ Paulo, Brazil.", "content": "Epidemic disease due to serogroup C Neisseria meningitidis in Saõ Paulo, Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207309"} {"pmid": "4207311", "title": "Vitamin A-induced nonspecific resistance to infection.", "content": "Vitamin A-induced nonspecific resistance to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207311"} {"pmid": "4207312", "title": "Letter: Wound infection with Shigella flexneri.", "content": "Letter: Wound infection with Shigella flexneri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207312"} {"pmid": "4207313", "title": "Letter: Dopa oxidase bands.", "content": "Letter: Dopa oxidase bands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207313"} {"pmid": "4207314", "title": "Blue-green algal proteins: assembly forms of C-phycocyanin from Synechococcus sp.", "content": "Blue-green algal proteins: assembly forms of C-phycocyanin from Synechococcus sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207314"} {"pmid": "4207304", "title": "The effect of intraspinal masses on flow in the epidural venous system.", "content": "The effect of intraspinal masses on flow in the epidural venous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207304"} {"pmid": "4207303", "title": "Imaging with radioactive microspheres to demonstrate maternal circulation in the placenta of rhesus monkeys.", "content": "Imaging with radioactive microspheres to demonstrate maternal circulation in the placenta of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207303"} {"pmid": "4207315", "title": "Thyrotropin releasing hormone: enhancement of DOPA activity in thyroidectomized rats.", "content": "Thyrotropin releasing hormone: enhancement of DOPA activity in thyroidectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207315"} {"pmid": "4207316", "title": "Remote nerve fibre bundle alterations in the retina as caused by argon laser photocoagulation.", "content": "Remote nerve fibre bundle alterations in the retina as caused by argon laser photocoagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207316"} {"pmid": "4207317", "title": "Bioconvection patterns in swimming microorganism cultures as an example of Rayleigh-Taylor instability.", "content": "Bioconvection patterns in swimming microorganism cultures as an example of Rayleigh-Taylor instability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207317"} {"pmid": "4207318", "title": "Decrease of polysomes in Tetrahymena after synchronisation shocks.", "content": "Decrease of polysomes in Tetrahymena after synchronisation shocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207318"} {"pmid": "4207319", "title": "Progress of a breeding project for non-human primates in Colombia.", "content": "Progress of a breeding project for non-human primates in Colombia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207319"} {"pmid": "4207320", "title": "Social hierarchy in monkeys (Macaca mulatta) modified by chlordiazepoxide hydrochloride.", "content": "Social hierarchy in monkeys (Macaca mulatta) modified by chlordiazepoxide hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207320"} {"pmid": "4207321", "title": "The use of immunoelectro-osmophoresis in the laboratory diagnosis of disseminated intravascular coagulation.", "content": "The use of immunoelectro-osmophoresis in the laboratory diagnosis of disseminated intravascular coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207321"} {"pmid": "4207322", "title": "The agar dilution method of testing the sensitivity of bacteria to antibiotics.", "content": "The agar dilution method of testing the sensitivity of bacteria to antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207322"} {"pmid": "4207323", "title": "Bacterial suspensions for the growth of Naegleria species.", "content": "Bacterial suspensions for the growth of Naegleria species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207323"} {"pmid": "4207324", "title": "Estimating lecithin-sphingomyelin area ratio in amniotic fluid. A modified method for the prediction of neonatal respiratory distress.", "content": "Estimating lecithin-sphingomyelin area ratio in amniotic fluid. A modified method for the prediction of neonatal respiratory distress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207324"} {"pmid": "4207325", "title": "Aspects of experimental hepatocarcinogenesis. I. Early hyperplastic foci.", "content": "Aspects of experimental hepatocarcinogenesis. I. Early hyperplastic foci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207325"} {"pmid": "4207326", "title": "Some aspects of epilepsy and convulsions in childhood.", "content": "Some aspects of epilepsy and convulsions in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207326"} {"pmid": "4207327", "title": "Radiolabeled chelates for visualization of kidney function and structure with emphasis on their use in renal insufficiency.", "content": "Radiolabeled chelates for visualization of kidney function and structure with emphasis on their use in renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207327"} {"pmid": "4207338", "title": "Exploratory behavior and activity of infant monkeys during nutritional and rearing restriction.", "content": "Exploratory behavior and activity of infant monkeys during nutritional and rearing restriction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207338"} {"pmid": "4207339", "title": "Nutritional vitamin B12 deficiency in rhesus monkeys.", "content": "Nutritional vitamin B12 deficiency in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207339"} {"pmid": "4207340", "title": "Evaluation of the nutritional quality of food supplies: prediction of \"desirable\" or \"safe\" protein: calorie ratios.", "content": "Evaluation of the nutritional quality of food supplies: prediction of \"desirable\" or \"safe\" protein: calorie ratios.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207340"} {"pmid": "4207341", "title": "Chromium nutrition in man.", "content": "Chromium nutrition in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207341"} {"pmid": "4207342", "title": "Studies on the antimalarial effects of RC-12 and WR 14,997 on the development of Plasmodium cynomolgi in mosquitoes and Rhesus monkeys.", "content": "Studies on the antimalarial effects of RC-12 and WR 14,997 on the development of Plasmodium cynomolgi in mosquitoes and Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207342"} {"pmid": "4207343", "title": "Schistosomiasis haematobia in African, hamadryas, and gelada baboons.", "content": "Schistosomiasis haematobia in African, hamadryas, and gelada baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207343"} {"pmid": "4207346", "title": "Health and health services in the United States. A perspective and a discussion of some issues.", "content": "Health and health services in the United States. A perspective and a discussion of some issues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207346"} {"pmid": "4207345", "title": "Latent radiation injury of lungs or heart activated by steroid withdrawal.", "content": "Latent radiation injury of lungs or heart activated by steroid withdrawal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207345"} {"pmid": "4207347", "title": "Letter: Lingual thyroid.", "content": "Letter: Lingual thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207347"} {"pmid": "4207348", "title": "Letter: Psuedomonas septicemia and splenectomy.", "content": "Letter: Psuedomonas septicemia and splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207348"} {"pmid": "4207349", "title": "Improved management of esophageal perforation: exclusion and diversion in continuity.", "content": "Improved management of esophageal perforation: exclusion and diversion in continuity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207349"} {"pmid": "4207350", "title": "Small intestinal atresia: the critical role of a functioning anastomosis.", "content": "Small intestinal atresia: the critical role of a functioning anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207350"} {"pmid": "4207352", "title": "Porcine aortic valves as replacements for human heart valves.", "content": "Porcine aortic valves as replacements for human heart valves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207352"} {"pmid": "4207351", "title": "Candida sepsis: pathogenesis and principles of treatments.", "content": "Candida sepsis: pathogenesis and principles of treatments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207351"} {"pmid": "4207353", "title": "Pharmacological evaluation of 3-(N-3,3-diphenylpropyl-N-methyl)-aminopropan-1-ol-hydrochloride (PF-82), a new type of antidepressant drug.", "content": "Pharmacological evaluation of 3-(N-3,3-diphenylpropyl-N-methyl)-aminopropan-1-ol-hydrochloride (PF-82), a new type of antidepressant drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207353"} {"pmid": "4207355", "title": "Mannosidosis: detection of the disease and of heterozygotes using serum and leucocytes.", "content": "Mannosidosis: detection of the disease and of heterozygotes using serum and leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207355"} {"pmid": "4207356", "title": "Synthesis of diphtheria toxin in E. coli cell-free lysate.", "content": "Synthesis of diphtheria toxin in E. coli cell-free lysate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207356"} {"pmid": "4207357", "title": "Effects of the diastereoisomers of methylenetetrahydrofolate on the reaction catalyzed by thymidylate synthetase.", "content": "Effects of the diastereoisomers of methylenetetrahydrofolate on the reaction catalyzed by thymidylate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207357"} {"pmid": "4207361", "title": "Conjugation in Tetrahymena: the relationship between the division cycle and cell pairing.", "content": "Conjugation in Tetrahymena: the relationship between the division cycle and cell pairing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207361"} {"pmid": "4207362", "title": "Drosophilia myogenesis in vitro: the genesis of \"small\" myocytes and myotubes.", "content": "Drosophilia myogenesis in vitro: the genesis of \"small\" myocytes and myotubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207362"} {"pmid": "4207363", "title": "Permeabilization of Drosophila eggs.", "content": "Permeabilization of Drosophila eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207363"} {"pmid": "4207365", "title": "Assessors of fetal perinatal mortality in diabetic pregnancy. Analysis of 1,332 pregnancies in the Copenhagen series, 1946-1972.", "content": "Assessors of fetal perinatal mortality in diabetic pregnancy. Analysis of 1,332 pregnancies in the Copenhagen series, 1946-1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207365"} {"pmid": "4207364", "title": "Observations on lipolysis in ketosis-resistant, growth-onset diabetes.", "content": "Observations on lipolysis in ketosis-resistant, growth-onset diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207364"} {"pmid": "4207367", "title": "Inhibition by somatostatin on the release of TSH induced in man by thyrotropin-releasing factor.", "content": "Inhibition by somatostatin on the release of TSH induced in man by thyrotropin-releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207367"} {"pmid": "4207366", "title": "Homeostasis of body weight in a diabetes clinic population.", "content": "Homeostasis of body weight in a diabetes clinic population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207366"} {"pmid": "4207369", "title": "Thermal inactivation of thyroxine-binding globulin for direct radioimmunoassay of triiodothyronine in serum.", "content": "Thermal inactivation of thyroxine-binding globulin for direct radioimmunoassay of triiodothyronine in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207369"} {"pmid": "4207358", "title": "Phagocytic activity of macrophages from C57-Bl and CBA mice.", "content": "Phagocytic activity of macrophages from C57-Bl and CBA mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207358"} {"pmid": "4207368", "title": "Effect of acute and long-standing hypocalcemia on blood pressure and plasma renin activity in man.", "content": "Effect of acute and long-standing hypocalcemia on blood pressure and plasma renin activity in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207368"} {"pmid": "4207360", "title": "Two Bence Jones proteins of different immunological type (light chains kappa and lambda) in a case of micromolecular myeloma.", "content": "Two Bence Jones proteins of different immunological type (light chains kappa and lambda) in a case of micromolecular myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207360"} {"pmid": "4207370", "title": "Failure of somatostatin to suppress thyrotropin releasing factor and luteinizing hormone releasing factor-induced growth hormone release in acromegaly.", "content": "Failure of somatostatin to suppress thyrotropin releasing factor and luteinizing hormone releasing factor-induced growth hormone release in acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207370"} {"pmid": "4207371", "title": "Maternal dietary deficiency and cellular development of progeny in the rat.", "content": "Maternal dietary deficiency and cellular development of progeny in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207371"} {"pmid": "4207359", "title": "Values of the IgG, IgA, IgM immunoglobulins and of the fraction C'3 of the complement in 200 normal subjects.", "content": "Values of the IgG, IgA, IgM immunoglobulins and of the fraction C'3 of the complement in 200 normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207359"} {"pmid": "4207372", "title": "Radiation therapy of inoperable localized prostate carcinoma: an assessment of tumor response and complications.", "content": "Radiation therapy of inoperable localized prostate carcinoma: an assessment of tumor response and complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207372"} {"pmid": "4207373", "title": "Thydrotropin releasing hormone: antagonism of pentobarbital in rodents.", "content": "Thydrotropin releasing hormone: antagonism of pentobarbital in rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207373"} {"pmid": "4207374", "title": "Effect of carbonic anhydrase inhibition on shell penetration by the muricid gastropod Urosalpinx cinerea.", "content": "Effect of carbonic anhydrase inhibition on shell penetration by the muricid gastropod Urosalpinx cinerea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207374"} {"pmid": "4207375", "title": "Thyrotropin-releasing hormone is not the sole physiologic mediator of prolactin release during suckling.", "content": "Thyrotropin-releasing hormone is not the sole physiologic mediator of prolactin release during suckling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207375"} {"pmid": "4207376", "title": "Editorial: Control of prolactin in man.", "content": "Editorial: Control of prolactin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207376"} {"pmid": "4207377", "title": "Letter: Quantitation of nerve-growth-stimulating activity.", "content": "Letter: Quantitation of nerve-growth-stimulating activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207377"} {"pmid": "4207378", "title": "Gene dosage compensation in metafemales (3X;2A) of Drosophila.", "content": "Gene dosage compensation in metafemales (3X;2A) of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207378"} {"pmid": "4207379", "title": "Non-specific \"pairing\" of DNA molecules by recombination enzyme of Bacillus subtilis.", "content": "Non-specific \"pairing\" of DNA molecules by recombination enzyme of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207379"} {"pmid": "4207381", "title": "Pulmonary embolism complicating permanent cardiac pacing.", "content": "Pulmonary embolism complicating permanent cardiac pacing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207381"} {"pmid": "4207382", "title": "Letter: Heterotopic bone formation in abdominal scars.", "content": "Letter: Heterotopic bone formation in abdominal scars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207382"} {"pmid": "4207383", "title": "The significance of epileptic seizures in infancy and childhood.", "content": "The significance of epileptic seizures in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207383"} {"pmid": "4207385", "title": "Acute pressure changes and possible secondary tissue changes due to laser or xenon photocoagulation.", "content": "Acute pressure changes and possible secondary tissue changes due to laser or xenon photocoagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207385"} {"pmid": "4207386", "title": "A low-molecular-weight protein cross-reacting with human liver N-acetyl-beta-D-glucosaminidase.", "content": "A low-molecular-weight protein cross-reacting with human liver N-acetyl-beta-D-glucosaminidase. Antisera were raised to preparations of hexosaminidase isoenzymes A and B purified from human liver. Protein that cross-reacted with the liver hexosaminidase was detected by an antibody-consumption method. A cross-reacting protein with a low molecular weight (20000) was partially characterized and purified from control human liver. This protein is also present in the liver of patients with Tay-Sachs disease or with Sandhoff's disease. Hexosaminidases A and B gave an immunological reaction of partial identity with the low-molecular-weight protein. The possible identity of the low-molecular-weight cross-reacting protein as a subunit of hexosaminidase is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207386"} {"pmid": "4207387", "title": "Mannosidosis in Angus cattle. The enzymic defect.", "content": "Mannosidosis in Angus cattle. The enzymic defect. Normal calf alpha-mannosidase activity exists in at least three forms separable by chromatography on DEAE-cellulose and by starch-gel electrophoresis. Two components, A and B, have optimum activity between pH3.75 and 4.75, but component C has an optimum of pH6.6. Components A and B are virtually absent from the tissues of a calf with mannosidosis and the residual activity is due to component C. The acidic and neutral forms of alpha-mannosidase differ in their molecular weights and sensitivity to EDTA, Zn(2+), Co(2+) and Mn(2+). An acidic alpha-mannosidase component (pH optimum 4.0) accounts for most of the activity in normal plasma but it is absent from the plasma of a calf with mannosidosis. Although the acidic alpha-mannosidase component is probably related to tissue components A and B, it can be distinguished from them by ion-exchange chromatography and gel filtration. The optimum pH of the low residual activity in the plasma from a calf with mannosidosis is pH5.5-5.75. The results support the hypothesis that Angus-cattle mannosidosis is a storage disease caused by a deficiency of lysosomal acidic alpha-mannosidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207387"} {"pmid": "4207389", "title": "Dihydrofolate reductase: low-resolution mass-spectrometric analysis of an elastase digest as a sequencing tool.", "content": "Dihydrofolate reductase: low-resolution mass-spectrometric analysis of an elastase digest as a sequencing tool. An elastase digest of a protein of unknown structure, dihydrofolate reductase, was studied by mass spectrometry. This soluble digest contained a large number of small peptides in different yields, within the ideal molecular-weight range (200-1200) for mixture-analysis mass spectrometry. Sequences of the major component peptides in the digest are reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207389"} {"pmid": "4207388", "title": "Cathepsin B1. A lysosomal enzyme that degrades native collagen.", "content": "Cathepsin B1. A lysosomal enzyme that degrades native collagen. 1. Experiments were made to determine whether the purified lysosomal proteinases, cathepsins B1 and D, degrade acid-soluble collagen in solution, reconstituted collagen fibrils, insoluble collagen or gelatin. 2. At acid pH values cathepsin B1 released (14)C-labelled peptides from collagen fibrils reconstituted at neutral pH from soluble collagen. The purified enzyme required activation by cysteine and EDTA and was inhibited by 4-chloromercuribenzoate, by the chloromethyl ketones derived from tosyl-lysine and acetyltetra-alanine and by human alpha(2)-macroglobulin. 3. Cathepsin B1 degraded collagen in solution, the pH optimum being pH4.5-5.0. The initial action was cleavage of the non-helical region containing the cross-link; this was seen as a decrease in viscosity with no change in optical rotation. The enzyme also attacked the helical region of collagen by a mechanism different from that of mammalian neutral collagenase. No discrete intermediate products of a specific size were observed in segment-long-spacing crystalloids (measured as native collagen molecules aligned with N-termini together along the long axis) or as separate peaks on gel filtration chromatography. This suggests that once an alpha-chain was attacked it was rapidly degraded to low-molecular-weight peptides. 4. Cathepsin B1 degraded insoluble collagen with a pH optimum below 4; this value is lower than that found for the soluble substrate, and a possible explanation is given. 5. The lysosomal carboxyl proteinase, cathepsin D, had no action on collagen or gelatin at pH3.0. Neither cathepsin B1 nor D cleaved Pz-Pro-Leu-Gly-Pro-d-Arg. 6. Cathepsin B1 activity was shown to be essential for the degradation of collagen by lysosomal extracts. 7. Cathepsin B1 may provide an alternative route for collagen breakdown in physiological and pathological situations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207388"} {"pmid": "4207390", "title": "Mild and efficient solubilization of Escherichia coli cells for the analysis of chromosomal DNA by sucrose gradient centrifugation.", "content": "Mild and efficient solubilization of Escherichia coli cells for the analysis of chromosomal DNA by sucrose gradient centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207390"} {"pmid": "4207391", "title": "Proceedings: An oxygen electrode for cranial implantation.", "content": "Proceedings: An oxygen electrode for cranial implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207391"} {"pmid": "4207392", "title": "Relation between zinc and iron and peroxidation of lipids in liver homogenate in CaEDTA-treated rats.", "content": "Relation between zinc and iron and peroxidation of lipids in liver homogenate in CaEDTA-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207392"} {"pmid": "4207394", "title": "Liquid formula and chemically defined diets.", "content": "Liquid formula and chemically defined diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207394"} {"pmid": "4207395", "title": "The effects of thrombin on phytohemagglutinin receptor sites in human platelets.", "content": "The effects of thrombin on phytohemagglutinin receptor sites in human platelets. We have previously demonstrated that lentil phytohemagglutinin (lentil-PHA) binds to human platelet membranes without causing either aggregation or the release reaction. When platelets are treated with thrombin, there is an increase in lentil-PHA binding suggesting the appearance of new receptor sites on the cell surface. We prepared a lentil-PHA-ferritin conjugate using affinity chromatography which was used to saturate cell surface receptor sites. Studies using this conjugate suggest that thrombin causes a complex change in the platelet surface involving a decrease in the number of lentil-PHA receptor sites on the external platelet surface with a marked increase in sites within the center of the canalicular system. These increased sites may result from fusion of granule membranes with the canalicular membranes during the secretion process. There is no obvious relationship between lentil-PHA receptor sites and intramembranous particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207395"} {"pmid": "4207398", "title": "Membrane junctions in the intermembrane space of mitochondria from mammalian tissues.", "content": "Membrane junctions in the intermembrane space of mitochondria from mammalian tissues. There have been several reports describing paracrystalline arrays in the intermembrane space of mitochondria. On closer inspection these structures appear to be junctions of two adjoining membranes. There are two types. They can be formed between the outer and inner mitochondrial membranes (designated outer-inner membrane junctions) or between two cristal membranes (intercristal membrane junctions). In rat heart, adjoining membranes appeared associated via a central dense midline approximately 30 A wide. In rat kidney, the junction had a ladder-like appearance with electron-dense \"bridges\" approximately 80 A wide, spaced 130 A apart, connecting the adjoining membranes. We have investigated the conditions which favor the visualization of such structures in mitochondria. Heart mitochondria isolated rapidly from fresh tissue (within 30 min of death) contain membrane junctions in approximately 10-15% of the cross sections. This would indicate that the percentage of membrane junctions in the entire mitochondrion is far greater. Mitochondria isolated from heart tissue which was stored for 1 h at 0 degrees -4 degrees C showed an increased number of membrane junctions, so that 80% of the mitochondrial cross sections show membrane junctions. No membrane junctions are observed in mitochondria in rapidly fixed fresh tissue or in mitochondria isolated from tissue disrupted in fixative. Thus, the visualization of junctions in the intermembrane space of mitochondria appears to be dependent upon the storage of tissue after death. Membrane junctions can also be observed in mitochondria from other stored tissues such as skeletal muscle, kidney, and interstitial cells from large and small intestine. In each case, no such junctions are observed in these tissues when they are fixed immediately after removal from the animal. It would appear that most studies in the literature in which isolated mitochondria from tissues such as heart or kidney were used were carried out on mitochondria which contained membrane junctions. The presence of such structures does not significantly affect normal mitochondrial function in terms of respiratory control and oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207398"} {"pmid": "4207397", "title": "Mitochondrial and cytoplasmic ribosomes from Tetrahymena pyriformis. Correlative analysis by gel electrophoresis and electron microscopy.", "content": "Mitochondrial and cytoplasmic ribosomes from Tetrahymena pyriformis. Correlative analysis by gel electrophoresis and electron microscopy. Mitochondrial and cytoplasmic ribosomes from Tetrahymena pyriformis have been isolated and studied by the techniques of polyacrylamide gel electrophoresis and electron microscopy used in conjunction. Although the two ribosome types show the same coefficient of sedimentation (80S) in sucrose gradients, they can be distinguished by gel electrophoresis: mitoribosomes migrate in a single band, considerably slower than the cytoribosome band. Electron microscope observations of negatively stained cytoribosomes show typical rounded or triangular profiles, about 275 x 230 A; mitoribosome profiles are much larger and clearly elongate, about 370 x 240 A. An electron-opaque spot delimits two nearly equal size subunits. In mixtures of mito- and cytoribosomes, each type can be recognized by its characteristic electrophoretic mobility and by its distinctive fine structure. Cytoribosomal 60S and 40S subunits each produce a distinct electrophoretic band. On the contrary, neither electrophoretic analysis, using a variety of conditions, nor electron microscopy is able to discern two different subunit types in the single 55S mitoribosomal subunit peak. Electrophoretic analysis of RNA shows that both ribosomal RNA species are present in the mitoribosomal subunit fraction. These results establish that mitoribosomes from T. pyriformis dissociate into two subunits endowed with the same sedimentation coefficient, the same electrophoretic mobility, and a similar morphology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207397"} {"pmid": "4207396", "title": "Effects of serum on membrane transport. II. Serum and the stimulation of adenosine transport, a possible mechanism.", "content": "Effects of serum on membrane transport. II. Serum and the stimulation of adenosine transport, a possible mechanism. When monolayers of freshly obtained rabbit lung macrophages are exposed to the nucleoside analogue, showdomycin (sho), adenosine transport, measured over a 45 s interval, is irreversibly inhibited. Low doses of the drug or short periods of exposure, however, do not result in decreased transport, while higher concentrations or longer exposures result in exponential decline. The initial lag is not due to a long reaction time of sho with the transport carrier or to nonspecific sites absorbing the drug. Previously it was shown that preincubation of monolayers with normal rabbit serum (NRS) results in increased adenosine transport. When monolayers are first exposed to sho so as to inhibit transport to varying degrees and then incubated with NRS, transport is increased over the inhibited level. Several experiments make it unlikely that serum removes the drug from the cell surface in a nonspecific fashion. Moreover, serum given before, during, or after sho alters the dose response curve so that no shoulder is seen. One way to explain these results makes use of target theory: the adenosine transport system could be comprised mainly of \"coupled\" or \"clustered\" sites of which only one is active at any time as well as \"hidden\" sites which are inactive. When a site in a group is irreversibly inactivated by sho, another in the group becomes activated. Serum might activate or uncouple all sites and also cause the appearance of hidden sites, which previously neither transported nor bound sho.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207396"} {"pmid": "4207399", "title": "Radium uptake by fresh water algae.", "content": "Radium uptake by fresh water algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207399"} {"pmid": "4207401", "title": "Contribution to knowledge of factors participating in virulence of Listeria monocytogenes. I. Isolation and properties of the biologically active complex E.", "content": "Contribution to knowledge of factors participating in virulence of Listeria monocytogenes. I. Isolation and properties of the biologically active complex E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207401"} {"pmid": "4207402", "title": "Homogeneity of Rickettsia prowazeki E strain egg culture as to the capacity to increase virulence in passages on white mouse lungs.", "content": "Homogeneity of Rickettsia prowazeki E strain egg culture as to the capacity to increase virulence in passages on white mouse lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207402"} {"pmid": "4207403", "title": "The need for field-laboratory facilities for primate research.", "content": "The need for field-laboratory facilities for primate research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207403"} {"pmid": "4207404", "title": "The sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (Macaca fascicularis).", "content": "The sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (Macaca fascicularis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207404"} {"pmid": "4207405", "title": "Two distinctive types of owl monkeys (Aotus).", "content": "Two distinctive types of owl monkeys (Aotus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207405"} {"pmid": "4207406", "title": "The ABO blood groups in vervet monkeys (Cercopithecus pygerythrus F. Cuvier).", "content": "The ABO blood groups in vervet monkeys (Cercopithecus pygerythrus F. Cuvier).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207406"} {"pmid": "4207407", "title": "Vascular heterograft: human umbilical cord vein as an aortic substitute in baboon. A preliminary report.", "content": "Vascular heterograft: human umbilical cord vein as an aortic substitute in baboon. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207407"} {"pmid": "4207408", "title": "Comparison of two early separation and weaning schedules of infant rhesus monkeys (Macaca mulatta).", "content": "Comparison of two early separation and weaning schedules of infant rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207408"} {"pmid": "4207409", "title": "Lymphocyte transformation induced by culture media supplemented with primate serum.", "content": "Lymphocyte transformation induced by culture media supplemented with primate serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207409"} {"pmid": "4207410", "title": "Single toxic doses of 131-I: administration to Macaca mulatta. Preliminary report.", "content": "Single toxic doses of 131-I: administration to Macaca mulatta. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207410"} {"pmid": "4207411", "title": "Depression of polymorph counts by various scrapie agents.", "content": "Depression of polymorph counts by various scrapie agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207411"} {"pmid": "4207412", "title": "Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone.", "content": "Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207412"} {"pmid": "4207413", "title": "Mechanisms for control of neural activity of the cerebral association cortex. I. The occurrence of augmenting potentials in the frontal granular cortex during stimulations of the nucleus medialis dorsalis.", "content": "Mechanisms for control of neural activity of the cerebral association cortex. I. The occurrence of augmenting potentials in the frontal granular cortex during stimulations of the nucleus medialis dorsalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207413"} {"pmid": "4207414", "title": "Mechanisms for control of neural activity of the cerebral association cortex. II. The occurrence of recruiting type of potentials in the frontal granular cortex during stimulations of medial thalamus.", "content": "Mechanisms for control of neural activity of the cerebral association cortex. II. The occurrence of recruiting type of potentials in the frontal granular cortex during stimulations of medial thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207414"} {"pmid": "4207420", "title": "Post-prandial EEG synchronization in normal and hypothalamically lesioned rats.", "content": "Post-prandial EEG synchronization in normal and hypothalamically lesioned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207420"} {"pmid": "4207421", "title": "Operant discrimination of interoceptive urinary bladder stimulation in the monkey.", "content": "Operant discrimination of interoceptive urinary bladder stimulation in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207421"} {"pmid": "4207422", "title": "Interocular reversal of up-down mirror images in pigeons.", "content": "Interocular reversal of up-down mirror images in pigeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207422"} {"pmid": "4207423", "title": "Producing and interpreting experimental olfactory deficits.", "content": "Producing and interpreting experimental olfactory deficits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207423"} {"pmid": "4207424", "title": "Sleep induced by hypothalamic self-stimulation in cat.", "content": "Sleep induced by hypothalamic self-stimulation in cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207424"} {"pmid": "4207434", "title": "Polymers in medicine.", "content": "Polymers in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207434"} {"pmid": "4207425", "title": "Cardiac involvement in inherited disorders of metabolism.", "content": "Cardiac involvement in inherited disorders of metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207425"} {"pmid": "4207435", "title": "Biopolymers: origin, chemistry, and biology.", "content": "Biopolymers: origin, chemistry, and biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207435"} {"pmid": "4207436", "title": "Cis-trans-isomerism of thyrotropin releasing hormone (TRH) in aqueous solution.", "content": "Cis-trans-isomerism of thyrotropin releasing hormone (TRH) in aqueous solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207436"} {"pmid": "4207439", "title": "Food poisoning due to Vibrio parahaemolyticus.", "content": "Food poisoning due to Vibrio parahaemolyticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207439"} {"pmid": "4207490", "title": "Immunological studies on human salivary albumin.", "content": "Immunological studies on human salivary albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207490"} {"pmid": "4207491", "title": "Effect of anti-cell and anti-axial filament sera on Leptospira.", "content": "Effect of anti-cell and anti-axial filament sera on Leptospira.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207491"} {"pmid": "4207492", "title": "The reaction of near-isogenic lines of flax to the rust fungus Melampsora lini. II. Biochemical studies.", "content": "The reaction of near-isogenic lines of flax to the rust fungus Melampsora lini. II. Biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207492"} {"pmid": "4207493", "title": "Properties of genetically polymorphic isozymes of alcohol dehydrogenase in Drosophila melanogaster.", "content": "Properties of genetically polymorphic isozymes of alcohol dehydrogenase in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207493"} {"pmid": "4207495", "title": "Alkaline phosphatase of Drosophila melanogaster. 3. Tyrosine-O-phosphate as substrate.", "content": "Alkaline phosphatase of Drosophila melanogaster. 3. Tyrosine-O-phosphate as substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207495"} {"pmid": "4207494", "title": "The relative quantities and catalytic activities of enzymes produced by alleles at the alcohol dehydrogenase locus in Drosophila melanogaster.", "content": "The relative quantities and catalytic activities of enzymes produced by alleles at the alcohol dehydrogenase locus in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207494"} {"pmid": "4207496", "title": "Pteridine diuretics as biopterin antagonists.", "content": "Pteridine diuretics as biopterin antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207496"} {"pmid": "4207497", "title": "Preparation of human kininogen. 3. Enzymatic digestion and modification.", "content": "Preparation of human kininogen. 3. Enzymatic digestion and modification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207497"} {"pmid": "4207498", "title": "Effects of the mycotoxin sporidesmin on swelling and respiration of liver mitochondria.", "content": "Effects of the mycotoxin sporidesmin on swelling and respiration of liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207498"} {"pmid": "4207499", "title": "The involvement of the disulphide group of sporidesmin in the action of the toxin on swelling and respiration of liver mitochondria.", "content": "The involvement of the disulphide group of sporidesmin in the action of the toxin on swelling and respiration of liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207499"} {"pmid": "4207500", "title": "Lymphographic appearances in Waldenstrom's macroglobulinaemia.", "content": "Lymphographic appearances in Waldenstrom's macroglobulinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207500"} {"pmid": "4207502", "title": "Eosinophillic granuloma of the lung with sawdust and horse protein hypersensitivity.", "content": "Eosinophillic granuloma of the lung with sawdust and horse protein hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207502"} {"pmid": "4207504", "title": "Experimental extrinsic allergic alveolitis induced in the guinea-pig with Streptomyces olivaceus.", "content": "Experimental extrinsic allergic alveolitis induced in the guinea-pig with Streptomyces olivaceus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207504"} {"pmid": "4207503", "title": "Farmer's lung following inhalation of Aspergillus flavus growing in mouldy corn.", "content": "Farmer's lung following inhalation of Aspergillus flavus growing in mouldy corn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207503"} {"pmid": "4207506", "title": "Persistent scabious nodules.", "content": "Persistent scabious nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207506"} {"pmid": "4207509", "title": "Mutagenicity experiments with the tranquillizer meprobamate in Drosophila melanogaster and in human leukocyte chromosomes in vitro.", "content": "Mutagenicity experiments with the tranquillizer meprobamate in Drosophila melanogaster and in human leukocyte chromosomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207509"} {"pmid": "4207513", "title": "Existence of two distinct hemolysins in Vibrio parahaemolyticus.", "content": "Existence of two distinct hemolysins in Vibrio parahaemolyticus. Two distinct hemolysins were demonstrated in Vibrio parahaemolyticus. A thermostable direct hemolysin purified from V. parahemolyticus WP-1, a Kanagawa phenomenon (KP)-positive strain, is antigenically different from a thermolabile hemolysin produced by V. parahaemolyticus T-3454, a KP-negative strain. The thermostable direct hemolysin was found in KP-positive strains but not in KP-negative strains. On the other hand, the thermolabile hemolysins were found in both KP-positive and -negative strains, although some KP-positive strains did not produce this hemolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207513"} {"pmid": "4207514", "title": "Assessment of germ tube dispersion activity of serum from experimental candidiasis: a new procedure for serodiagnosis.", "content": "Assessment of germ tube dispersion activity of serum from experimental candidiasis: a new procedure for serodiagnosis. Germ tubes of Candida albicans and C. stellatoidea clump in normal serum but disperse in serum from animals infected with either species of Candida. A new procedure for the assessment of grades of germ tube dispersion activity of serum is presented; this procedure is to count the number of freely dispersed germ tubes in test serum into which a definite number of yeast-type C. albicans has been inoculated. The relationship between the serum activity and macroscopic lesions caused by candidal infection is observed, indicating the possibility of applying the phenomenon to the serodiagnosis of deep-seated candidiasis. The specificity and sensitivity of the test are also examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207514"} {"pmid": "4207515", "title": "Enhanced in vitro phagocytosis of Listeria monocytogenes by human monocytes in the presence of ampicillin, tetracycline, and chloramphenicol.", "content": "Enhanced in vitro phagocytosis of Listeria monocytogenes by human monocytes in the presence of ampicillin, tetracycline, and chloramphenicol. An in vitro system was developed to test the phagocytic activity of human macrophages grown from blood monocytes in the presence of the antibiotics ampicillin, tetracycline, and chloramphenicol. (3)H-labeled Listeria monocytogenes served as test organism. Subinhibitory amounts of the antibiotics enhanced the phagocytic activity significantly (P < 0.025). Macrophages pretreated with the drugs in identical concentrations showed the same phagocytic activity as control cells in the absence of the drugs. Because the drug concentrations used were similar to those that may be attained in man at certain places of inflammation, enhanced phagocytosis in the presence of antibiotics may have clinical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207515"} {"pmid": "4207516", "title": "Serological and cellular immune activity of peptidoglucomannan fractions of Candida albicans cell walls.", "content": "Serological and cellular immune activity of peptidoglucomannan fractions of Candida albicans cell walls. A two-stage extraction of isolated cell walls of C. albicans resulted in 45% solubilization into antigens of high molecular weight leaving a wall residue which also had antigenic properties. Ice-cold dilute alkali removed 25% of the defatted cell walls. The extract was nondialyzable, had a glucose-to-mannose ratio of 2:3 and an amino acid content of 7.32%, and was designated peptidoglucomannan (PGM). An additional 26% of the walls resistant to stage I were solubilized by sonic treatment yielding a fraction having a glucose-to-mannose ratio of 6:1, termed soluble mannoglucan (sMG). The residue after extraction and sonic treatment contained 10.9% mannose, which was the insoluble mannoglucan. The gel permeation behavior of PGM and sMG on BioGel A5M was similar; each contained two components, one estimated to exceed 5 x 10(6) molecular weight and a second smaller species. The soluble cell wall fractions were active in immunodiffusion and carried antigenic group specificity. Immunoelectrophoresis of PGM, sMG, and mannan revealed some heterogeneity. The insoluble mannoglucan had agglutinating activity. A distinctive immunodiffusion pattern of cell wall antigens was formed with the serum of a leukemic patient with candidiasis. All three cell wall antigens and mannan elicited delayed-type hypersensitivity as measured by skin-test and specific inhibition of macrophage migration. A dose of 25 mug of PGM was sufficient to inhibit 89.9% migration in the peritoneal exudates of guinea pigs immunized with cell walls, and 10 mug of PGM inhibited 91.7% migration in guinea pigs immunized with insoluble mannoglucan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207516"} {"pmid": "4207519", "title": "Viability of L-phase variants after centrifugation.", "content": "Viability of L-phase variants after centrifugation. L-phase variants of several genera may be centrifuged with minimal, if any, loss of viability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207519"} {"pmid": "4207517", "title": "Differential attachment by piliated and nonpiliated Neisseria gonorrhoeae to human sperm.", "content": "Differential attachment by piliated and nonpiliated Neisseria gonorrhoeae to human sperm. Piliated type 1 Neisseria gonorrhoeae attached to 50% of human sperm after incubation of mixtures in vitro for 15 min at 35 C. In contrast, nonpiliated type 4 N. gonorrhoeae attached to only 23% of sperm. Similar results were obtained with three different strains of N. gonorrhoeae. Treatment with heat or formaldehyde to kill bacteria did not affect the amount of attachment by piliated or nonpiliated types. Escherichia coli and N. subflava, other species of piliated bacteria, attached to about 40% of sperm, and the nonpiliated species N. meningitidis and N. catarrhalis attached to a comparable number of sperm, as did type 4 N. gonorrhoeae. Prior incubation of type 1 N. gonorrhoeae with purified antibody prepared against gonococcal pili reduced the percentage of sperm with attached bacteria to the same level as that for nonpiliated type 4 gonococci. Similar treatment of other piliated organisms or of nonpiliated Neisseria did not affect the attachment of the bacteria to sperm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207517"} {"pmid": "4207518", "title": "BCG antibody profiles in tuberculoid and lepromatous leprosy.", "content": "BCG antibody profiles in tuberculoid and lepromatous leprosy. In sera from 12 patients with polar tuberculoid leprosy, 12 with subpolar tuberculoid leprosy, and 16 with lepromatous leprosy were demonstrated a total number of 125 anti-BCG precipitins by means of crossed immunoelectrophoresis with intermediate gel. Up to 14 different precipitins were found in individual sera, and the complexity in antibody response was higher than previously realized. The specificity of 69% of the antibodies was defined, and these antibodies were titrated in three arbitrary titer units. A highly significant difference (P < 0.002) was found in antibody response between the tuberculoid and the lepromatous group. Due to simplicity, sensitivity, and high resolution, the method used is a promising tool for providing exact data to be used as guidelines for purification of important individual mycobacterial antigens. The need for reference antisera is emphasized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207518"} {"pmid": "4207520", "title": "Rickettsial infectious antibody complexes: detection by antiglobulin plaque reduction technique.", "content": "Rickettsial infectious antibody complexes: detection by antiglobulin plaque reduction technique. Rickettsia rickettsii and R. australis formed infectious antibody complexes when reacted with homologous convalescent serum. The addition of antiglobulin to these complexes showed neutralization of plaques proportional to the concentration of rickettsial immune serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207520"} {"pmid": "4207522", "title": "Conization operation using an automated cutting device.", "content": "Conization operation using an automated cutting device.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207522"} {"pmid": "4207523", "title": "The treatment of pharyngeal pouch.", "content": "The treatment of pharyngeal pouch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207523"} {"pmid": "4207525", "title": "The rôle of zinc in promoting the opalescence and cold precipitation of boar seminal plasma. II. Relationship of a zinc-precipitable protein with the haemagglutinin.", "content": "The rôle of zinc in promoting the opalescence and cold precipitation of boar seminal plasma. II. Relationship of a zinc-precipitable protein with the haemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207525"} {"pmid": "4207526", "title": "Host DNA synthesis-suppressing factor in culture fluid of tissue cultures infected with measles virus.", "content": "Host DNA synthesis-suppressing factor in culture fluid of tissue cultures infected with measles virus. Host DNA synthesis is suppressed by the culture fluid of cell cultures infected with measles virus. This activity in the culture fluid is initiated somewhat later than the growth of infectious virus. Ninety percent of host DNA synthesis in HeLa cells is inhibited by culture fluid of 3-day-old cell cultures of Vero or HeLa cells infected with measles virus. This suppressing activity is not a property of the virion, but is due to nonvirion-associated component which shows none of the activities of measles virus such as hemagglutination, hemolysis, or cell fusion nor does it have the antigenicity of measles virus as tested by complement-fixation or hemagglutination-inhibiting antibody blocking tests. Neutralization of the activity of this component is not attained with the pooled sera of convalescent measles patients. This component has molecular weights of about 45,000, 20,000, and 3,000 and appears to be a heat-stable protein. The production of host DNA suppressing factor (DSF) is blocked by cycloheximide. Neither UV-inactivated nor antiserum-neutralized measles virus produce DSF. Furthermore, such activity of nonvirion-associated component is not detected in the culture fluid of cultures infected with other RNA viruses such as poliovirus, vesicular stomatitis virus, or Sindbis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207526"} {"pmid": "4207527", "title": "Scrapie and transmissible mink encephalopathy: search for infectious nucleic acid.", "content": "Scrapie and transmissible mink encephalopathy: search for infectious nucleic acid. Brain preparations from animals with scrapie or transmissible mink encephalopathy were phenol extracted and examined for the presence of pathogenic nucleic acid. Animals inoculated with various extracts remained healthy, and analysis on 2.6 to 5% polyacrylamide gels failed to detect a difference in extractable RNA species between infected and normal mink brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207527"} {"pmid": "4207528", "title": "The action of rubiflavin and other cytostatic antibiotics on Euglena gracilis.", "content": "The action of rubiflavin and other cytostatic antibiotics on Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207528"} {"pmid": "4207529", "title": "Chromosomal characteristics of a lymphoblastoid line from baboon Chacma Papio-papio: similarity to human lymphoblastoid lines.", "content": "Chromosomal characteristics of a lymphoblastoid line from baboon Chacma Papio-papio: similarity to human lymphoblastoid lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207529"} {"pmid": "4207521", "title": "Carbuncle: discussion and a report of two cases.", "content": "Carbuncle: discussion and a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207521"} {"pmid": "4207530", "title": "Physical and chemical abnormalities in a series of 155 paraproteinemic sera of the main immunoglobulin classes.", "content": "Physical and chemical abnormalities in a series of 155 paraproteinemic sera of the main immunoglobulin classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207530"} {"pmid": "4207531", "title": "Effects of ephemeral fever on milk production and reproduction of dairy cattle.", "content": "Effects of ephemeral fever on milk production and reproduction of dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207531"} {"pmid": "4207533", "title": "Intrauterine rubella infection.", "content": "Intrauterine rubella infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207533"} {"pmid": "4207532", "title": "Tracheobronchial anomalies in children.", "content": "Tracheobronchial anomalies in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207532"} {"pmid": "4207534", "title": "Agammaglobulinemia associated with Australia-antigen-positive chronic active hepatitis.", "content": "Agammaglobulinemia associated with Australia-antigen-positive chronic active hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207534"} {"pmid": "4207540", "title": "Significance of arterial lesions in the comparative pathology of spontaneous atherosclerosis.", "content": "Significance of arterial lesions in the comparative pathology of spontaneous atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207540"} {"pmid": "4207541", "title": "Accuracy and precision in measurement of human serum immunoglobulins G, A and M.", "content": "Accuracy and precision in measurement of human serum immunoglobulins G, A and M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207541"} {"pmid": "4207542", "title": "Presence in dental plaque of a polysaccharide antigen of the anaerobic oral filamentous organism Eubacterium saburreum.", "content": "Presence in dental plaque of a polysaccharide antigen of the anaerobic oral filamentous organism Eubacterium saburreum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207542"} {"pmid": "4207543", "title": "Fibrosarcoma with metastasis in a rhesus monkey.", "content": "Fibrosarcoma with metastasis in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207543"} {"pmid": "4207544", "title": "Experimental studies on the formation of epithelioid cells induced by fractionated substances of tubercle vacilli.", "content": "Experimental studies on the formation of epithelioid cells induced by fractionated substances of tubercle vacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207544"} {"pmid": "4207545", "title": "Immunochemical properties of rabbit antibodies in membranous glomerulonephritis.", "content": "Immunochemical properties of rabbit antibodies in membranous glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207545"} {"pmid": "4207546", "title": "Electron microscopical study on the tumor of von Recklinghausen's neurofibromatosis.", "content": "Electron microscopical study on the tumor of von Recklinghausen's neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207546"} {"pmid": "4207547", "title": "On non-specific inhibition of rat liver microsomal UDP glucuronyltransferase by some drugs.", "content": "On non-specific inhibition of rat liver microsomal UDP glucuronyltransferase by some drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207547"} {"pmid": "4207548", "title": "Epoxide hydrase in human liver biopsy specimens: assay and properties.", "content": "Epoxide hydrase in human liver biopsy specimens: assay and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207548"} {"pmid": "4207554", "title": "Pulpal response to a new composite dental restorative material.", "content": "Pulpal response to a new composite dental restorative material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207554"} {"pmid": "4207562", "title": "ATP-dependent deoxyribonuclease from normal and rec-mutant strains of Bacillus subtilis.", "content": "ATP-dependent deoxyribonuclease from normal and rec-mutant strains of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207562"} {"pmid": "4207563", "title": "Absence of nucleic acid in proteocin, a defective phage of Proteus mirabilis D52.", "content": "Absence of nucleic acid in proteocin, a defective phage of Proteus mirabilis D52.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207563"} {"pmid": "4207570", "title": "The repair of ultraviolet-damaged DNA in Bacillus subtilis.", "content": "The repair of ultraviolet-damaged DNA in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207570"} {"pmid": "4207569", "title": "Proceedings: Lysosomal enzymes in lymphocytes.", "content": "Proceedings: Lysosomal enzymes in lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207569"} {"pmid": "4207556", "title": "Proceedings: 122. Comparison of thermoregulatory responses in the Japanese monkey(Macaca fuscata) and the crab-eating monkey (Macaca irus) during cold exposure.", "content": "Proceedings: 122. Comparison of thermoregulatory responses in the Japanese monkey(Macaca fuscata) and the crab-eating monkey (Macaca irus) during cold exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207556"} {"pmid": "4207571", "title": "Leucocytes and thrombosis. II. Relationship between leucocyte behaviour and divalent cations, sulphydryl groups, red cells and adenosine diphosphate.", "content": "Leucocytes and thrombosis. II. Relationship between leucocyte behaviour and divalent cations, sulphydryl groups, red cells and adenosine diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207571"} {"pmid": "4207572", "title": "Involvement of small mammals in the transmission of scrub typhus in Malaysia: isolation and serological evidence.", "content": "Involvement of small mammals in the transmission of scrub typhus in Malaysia: isolation and serological evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207572"} {"pmid": "4207573", "title": "Toxoplasmosis in free-ranging chacma baboons (Papio ursinus) from the Kruger National Park.", "content": "Toxoplasmosis in free-ranging chacma baboons (Papio ursinus) from the Kruger National Park.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207573"} {"pmid": "4207574", "title": "Effects of immunosuppressive agents on the course of Trypanosoma (trypanozoon) brucei infections in heat-stressed mice.", "content": "Effects of immunosuppressive agents on the course of Trypanosoma (trypanozoon) brucei infections in heat-stressed mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207574"} {"pmid": "4207575", "title": "Exercise electrocardiography: recognition of the ischemic response, false positive and negative patterns.", "content": "Exercise electrocardiography: recognition of the ischemic response, false positive and negative patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207575"} {"pmid": "4207579", "title": "Ventricular contractility during controlled exercise and emotion in the primate.", "content": "Ventricular contractility during controlled exercise and emotion in the primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207579"} {"pmid": "4207577", "title": "Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris.", "content": "Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207577"} {"pmid": "4207578", "title": "Digesta passage and water exchange in the equine large intestine.", "content": "Digesta passage and water exchange in the equine large intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207578"} {"pmid": "4207576", "title": "Effects of perhexiline on symptomatic and hemodynamic responses to exercise in patients with angina pectoris.", "content": "Effects of perhexiline on symptomatic and hemodynamic responses to exercise in patients with angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207576"} {"pmid": "4207586", "title": "Amniotic fluid vitamin B12-binding protein. Purification and characterization with isoelectric focusing and other techniques.", "content": "Amniotic fluid vitamin B12-binding protein. Purification and characterization with isoelectric focusing and other techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207586"} {"pmid": "4207584", "title": "Two-trait selection and the genetic correlation. I. Prediction of responses in single-trait and in two-trait selection.", "content": "Two-trait selection and the genetic correlation. I. Prediction of responses in single-trait and in two-trait selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207584"} {"pmid": "4207585", "title": "Two-trait selection and the genetic correlation. II. Changes in the genetic correlation during two-trait selection.", "content": "Two-trait selection and the genetic correlation. II. Changes in the genetic correlation during two-trait selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207585"} {"pmid": "4207581", "title": "Heterotrophic potential for amino acid uptake in a naturally eutrophic lake.", "content": "Heterotrophic potential for amino acid uptake in a naturally eutrophic lake. The uptake of sixteen (14)C-labeled amino acids by the indigenous heterotrophic microflora of Upper Klamath Lake, Oregon, was measured using the kinetic approach. The year-long study showed a seasonal variation in the maximum uptake velocity, V(max), of all the amino acids which was proportional to temperature. The maximum total flux of amino acids by the heterotrophic microflora ranged from 1.2 to 11.9 mumol of C per liter per day (spring to summer). Glutamate, asparagine, aspartate, and serine had the highest V(max) values and were respired to the greatest extent. The percentages of the gross (net + respired) uptake of the amino acids which were respired to CO(2) ranged from 2% for leucine to 63% for glutamate. Serine, lysine, and glycine were the most abundant amino acids found in Upper Klamath Lake surface water; at intermediate concentrations were alanine, aspartate, and threonine; and the remaining amino acids were always below 7.5 x 10(-8) M (10 mug/liter). The amino acid concentrations determined chemically appear to be the sum of free and adsorbed amino acids, since the values obtained were usually greater than the (K(t) + S(n)) values obtained by the heterotrophic uptake experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207581"} {"pmid": "4207582", "title": "Scanning electron microscope study of Neisseria gonorrhoeae.", "content": "Scanning electron microscope study of Neisseria gonorrhoeae. Morphological studies utilizing various microscopy techniques have aided in our understanding of the gonococcus and gonorrhea. In this study scanning electron microscopy was used to study differences in virulent (colony types 1 and 2) and avirulent (colony types 3 and 4) gonococci relative to colony appearance, patterns of growth in liquid media, and surface features of individual cocci. Colony types of virulent gonococci are smaller in diameter but have a higher evaluation than those of avirulent mutants. Colony type 2 has a convex undersurface that is associated with surface pitting of solid media. When the colonies are grown in liquid media, various degrees of autoagglutination are observed; this is most pronounced with type 2 and least evident with type 4. Although pili may be involved in this phenomena, other mechanisms must be employed, since type 3 gonococci that lack pili autoagglutinate. Pili are seen on types 1 and 2 and are absent from types 3 and 4. They appear as individual threads radiating from the bacteria or as bundles of pili attaching adjacent cocci. Another extracellular structure consists of small spherical bodies that can coat the bacteria surface, attach to pili, or exist free from other bacterial components. These spheres are least evident with type 4. The gonococcal surface is pebbly with multiple sulci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207582"} {"pmid": "4207580", "title": "Radioimmunoassay on polycarbonate membranes: a sensitive and simplified method for the detection and quantitation of antibody.", "content": "Radioimmunoassay on polycarbonate membranes: a sensitive and simplified method for the detection and quantitation of antibody. A new radioimmunoassay technique is described in which a sampling manifold and polycarbonate filter membranes are used. Antigen-antibody reactions take place on the membranes. The manifold permits the simultaneous running of 30 samples and a rapid wash technique in which the washing solution is introduced into the manifold wells and suctioned off from below. The polycarbonate membrane offers a distinct advantage over the cellulose acetate in that nonspecific protein adsorption is substantially reduced. Antigens employed are whole bacteria or soluble antigen coupled to Sepharose beads and are layered over the membrane surface. A radiolabeled antibody is used to measure the primary antigen-antibody interaction. The sensitivity of the procedure is equal to that of fluorescent antibody tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207580"} {"pmid": "4207587", "title": "Reaggregation studies on the polypeptide chains of calf lens alpha-crystallin.", "content": "Reaggregation studies on the polypeptide chains of calf lens alpha-crystallin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207587"} {"pmid": "4207589", "title": "Letter: Fascioliasis.", "content": "Letter: Fascioliasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207589"} {"pmid": "4207583", "title": "Energy dispersion x-ray analysis by scanning electron microscopy for measuring cellular elemental composition in bacterial cells.", "content": "Energy dispersion x-ray analysis by scanning electron microscopy for measuring cellular elemental composition in bacterial cells. The use of scanning electron microscopy in conjuction with energy dispersion analysis of X rays is presented as a technique in a novel application to in situ studies of cellular elemental composition. The method has been applied, in the example of its use reported here, to examining the effects of copper-chromearsenic wood preservative on growth and element uptake of selected bacteria in agar cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207583"} {"pmid": "4207590", "title": "Controlled trial of various anti-D dosages in suppression of Rh sensitization following pregnancy. Report to the Medical Research Council by the working party on the use of anti-D-immunoglobulin for the prevention of isoimmunization of Rh-negative women during pregnancy.", "content": "Controlled trial of various anti-D dosages in suppression of Rh sensitization following pregnancy. Report to the Medical Research Council by the working party on the use of anti-D-immunoglobulin for the prevention of isoimmunization of Rh-negative women during pregnancy. In a controlled trial phials containing 200 mug, 100 mug, 50 mug, or 20 mug of IgG anti-D were given to nearly 2,000 D-negative primiparae whose infants were D-positive and ABO-compatible. Only mothers whose serum lacked anti-D were included and the dose of anti-D was always given within 36 hours of delivery. Each phial contained the same total volume of immunoglobulin and the particular dose given to any patient was not known to the clinician. The anti-D content of the phials was estimated three times during the course of the trials and remained fairly constant. Six months after delivery the incidence of a positive indirect antiglobulin test result, indicating the presence of anti-D, in the four dose groups (with about 450 women in each group) was as follows: 0.22%, 0.23%, 0.44%, and 1.35%. The trend towards an increase in the frequency of failures as the dose decreases was significant at the level of P=0.02.In each dose group about 200 women were followed to the end of a second pregnancy with a D-positive infant. The failure rates (in order of decreasing dosage) as judged by a positive indirect antiglobulin test result at the second delivery were as follows: 1.5%, 1.1%, 1.5% and 2.9%. The differences between the dose groups were not statistically significant. The overall failure rate (1.7%) was about one-tenth of that expected in an untreated series. Though the results failed to prove any differences in success rates between doses of 200, 100, 50, and 20 mug of anti-D, they do suggest, in conformity with other evidence, that a dose of 20 mug is suboptimal for routine use. The results support the belief that a dose of 100 mug is adequate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207590"} {"pmid": "4207592", "title": "Comparative study of the effects of two copper compounds on the respiration and survival of Biomphalaria glabrata (mollusca: pulmonata).", "content": "Comparative study of the effects of two copper compounds on the respiration and survival of Biomphalaria glabrata (mollusca: pulmonata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207592"} {"pmid": "4207595", "title": "Epilepsy in cerebral hydatidosis.", "content": "Epilepsy in cerebral hydatidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207595"} {"pmid": "4207593", "title": "Clinical note: seizures and EEG activation after trimipramine.", "content": "Clinical note: seizures and EEG activation after trimipramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207593"} {"pmid": "4207596", "title": "Intracarotid pentylenetetrazol injections in the cat.", "content": "Intracarotid pentylenetetrazol injections in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207596"} {"pmid": "4207597", "title": "Basilar dendrite bundles of giant pyramidal cells.", "content": "Basilar dendrite bundles of giant pyramidal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207597"} {"pmid": "4207594", "title": "Diazepam treatment for acute convulsions in children. A report of 41 patients, three with plasma levels.", "content": "Diazepam treatment for acute convulsions in children. A report of 41 patients, three with plasma levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207594"} {"pmid": "4207609", "title": "The occurrence of antigens of Dermatophagoides farinae Hughes in allergenic extracts of house dust.", "content": "The occurrence of antigens of Dermatophagoides farinae Hughes in allergenic extracts of house dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207609"} {"pmid": "4207599", "title": "Aeruginocine typing of Pseudomonas aeruginosa.", "content": "Aeruginocine typing of Pseudomonas aeruginosa. Aeruginocine typing using eight indicator strains of Wahba on Bacto tryptone-glucose yeast extract Agar (Difco) with an incubation temperature of 32 degrees C was found to be a reproducible and easy method which could be readily adopted by a diagnostic clinical laboratory. The results of aeruginocine typing of 1500 strains of Ps. aeruginosa suggest that hospitals differ in the range and patterns of aeruginocine types of strains isolated in them. In addition to representatives of nine of the 10 pyocine types of Wahba, a large number of strains isolated in India were found to fall into other groups not described in Wahba's system. Hence, 20 new inhibition patterns (aeruginocine types) are proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207599"} {"pmid": "4207598", "title": "Behavioral control of firing patterns of normal and abnormal neurons in chronic epileptic cortex.", "content": "Behavioral control of firing patterns of normal and abnormal neurons in chronic epileptic cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207598"} {"pmid": "4207608", "title": "Temperature, crowding and other environmental pressures in Drosophila melanogaster (adult progeny numger).", "content": "Temperature, crowding and other environmental pressures in Drosophila melanogaster (adult progeny numger).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207608"} {"pmid": "4207606", "title": "Hyperalimentation hypophosphatemia: hematologic-neurologic dysfunction due to ATP depletion.", "content": "Hyperalimentation hypophosphatemia: hematologic-neurologic dysfunction due to ATP depletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207606"} {"pmid": "4207607", "title": "Paradoxical effects of isoproterenol, nitroglycerin and exercise in conscious dogs with myocardial ischemia.", "content": "Paradoxical effects of isoproterenol, nitroglycerin and exercise in conscious dogs with myocardial ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207607"} {"pmid": "4207612", "title": "Instability of nitroglycerin tablets.", "content": "Instability of nitroglycerin tablets. Nitroglycerin is a volatile substance which evaporates from tablets if strict precautions are not taken. The tablets kept in small, amber, tightly capped glass bottles in a refrigerator maintain their potency for three to five months if bottles are opened once a week. After five months the unused tablets should be discarded. Tablets kept in a pill box and carried with the patient will deteriorate in a week and should be discarded thereafter. Cotton, plastic or paper stuffed in the bottle and frequent opening will reduce the potency of NG tablets considerably. Physicians, pharmacists and drug manufacturers should supply full instructions to patients on how to prevent rapid deterioration of their supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207612"} {"pmid": "4207616", "title": "Hippocampal damage and schizophrenia: a critique of Mednick's theory.", "content": "Hippocampal damage and schizophrenia: a critique of Mednick's theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207616"} {"pmid": "4207611", "title": "Studies on heterologous immunity in schistosomiasis. 7. Observations on the development of acquired homologous and heterologous immunity to Schistosoma mansoni in baboons.", "content": "Studies on heterologous immunity in schistosomiasis. 7. Observations on the development of acquired homologous and heterologous immunity to Schistosoma mansoni in baboons. Observations were made on the development of immunity to Schistosoma mansoni in baboons using both homologous and heterologous systems. The baboons were immunized by either (a) a single exposure to cercariae of the homologous species S. mansoni, or (b) 1-2 exposures to cercariae of either a S. rodhaini/S. mansoni hybrid or a S. mattheei/S. haematobium hybrid, or (c) repeated exposure to the cercariae of S. rodhaini or S. bovis. Baboons immunized with 500 cercariae of the homologous parasite developed partial immunity to reinfection, as did the baboons immunized with multiple exposures to the heterologous cercariae of S. rodhaini and S. bovis, although these parasites produced neither adult worms nor eggs in the baboons. The hybrids gave rise to well-established adult worm infections, but produced less immunity, even though the S. rodhaini/S. mansoni hybrid was genetically very similar to S. mansoni. These results indicate that adult worms are not essential to produce a considerable degree of immunity to reinfection, which can be engendered by the earlier stages of the parasites. However, none of the immune responses prevented egg deposition in the tissues, and considerable pathological changes resulted from the challenge infection. These observations suggest that although heterologous infections show some promise as immunizing agents, further studies are needed of the pathological changes resulting from their use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207611"} {"pmid": "4207619", "title": "The effect of ascorbic acid and potassium ferricyanide as melanogenesis inhibitors on the development of pigmentation in Mexican axolotls.", "content": "The effect of ascorbic acid and potassium ferricyanide as melanogenesis inhibitors on the development of pigmentation in Mexican axolotls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207619"} {"pmid": "4207618", "title": "Vaccination against malaria: evaluation of a plasmodial vaccine fraction and a preliminary study of some immunologic adjuvants in a primate model system: a brief report.", "content": "Vaccination against malaria: evaluation of a plasmodial vaccine fraction and a preliminary study of some immunologic adjuvants in a primate model system: a brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207618"} {"pmid": "4207617", "title": "Diverticulum of the bladder with ureteral orifice opening into the diverticulum: report of case.", "content": "Diverticulum of the bladder with ureteral orifice opening into the diverticulum: report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207617"} {"pmid": "4207629", "title": "A new species of Pleistophora (Microsporida: Pleistophoridae) parasitic in the shrimp Palaemonetes pugio.", "content": "A new species of Pleistophora (Microsporida: Pleistophoridae) parasitic in the shrimp Palaemonetes pugio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207629"} {"pmid": "4207625", "title": "Susceptibility and immune response to experimental plague in two species of langurs and in African green (grivet) monkeys.", "content": "Susceptibility and immune response to experimental plague in two species of langurs and in African green (grivet) monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207625"} {"pmid": "4207628", "title": "Ultrastructure of Nosema oryzaephili and the taxonomic value of the polar filament.", "content": "Ultrastructure of Nosema oryzaephili and the taxonomic value of the polar filament.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207628"} {"pmid": "4207630", "title": "Mattesia bombi n. sp. (Neogregarinida: Ophrocystidae), a parasite of Bombus (Hymenoptera: Apidae).", "content": "Mattesia bombi n. sp. (Neogregarinida: Ophrocystidae), a parasite of Bombus (Hymenoptera: Apidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207630"} {"pmid": "4207624", "title": "Properties of plasminogen activators formed by neoplastic human cell cultures.", "content": "Properties of plasminogen activators formed by neoplastic human cell cultures. A series of human cell lines has been examined for fibrinolysis in culture. The sera that are activating for fibrinolysis by human cells are mouse, monkey, human, horse, and bovine. Individual human sera show considerable variation in the ability to activate fibrinolysis. In common with other neoplastic or transformed mammalian and avian cell cultures, human cell lines of neoplastic origin produce substantial amounts of plasminogen activator. Several cultures of nonmalignant origin also produce plasminogen activator, whereas cultures obtained from trypsinized human embryos, or from human embryonic skin do not. The human melanoma plasminogen activators are of two kinds: a major component with a mol wt of 50,000, and a minor species with a mol wt of approximately 60,000. Both are DFP sensitive, serine proteases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207624"} {"pmid": "4207622", "title": "Thrombocytopenia in experimental trypanosomiasis.", "content": "Thrombocytopenia in experimental trypanosomiasis. The effect of experimental trypanosomiasis on coagulation was studied because a patient in this hospital with Rhodesian trypanosomiasis developed thrombocytopenia with disseminated intravascular coagulation. Rats injected intraperitoneally with this strain of Trypanosoma rhodesiense consistently developed trypanosomiasis and severe thrombocytopenia without changes in hematocrit or concentration of fibrinogen or fibrin split products. At the time of 50% mortality (4-5 days) mean platelet counts per cubic millimeter of infected rats were 18,000+/-9,000 (+/-2 SEM) compared to 1,091,000+/-128,000 in uninfected controls. In vitro, concentrated trypanosomes and trypanosomefree supernates of disrupted organisms added to normal rat, rabbit, or human blood produced platelet aggregation within 30 min. This platelet aggregation was not blocked by inhibitors of ADP, kinins, or early or late components of complement. In vivo thrombocytopenia also occurred in infected rabbits congenitally deficient in C6 and in infected, splenectomized rats. Although the aggregating substance obtained from disrupted trypanosomes is heat-labile, it is active in the presence of complement inhibitors, suggesting that this trypanosomal product may be a protein enzyme or toxin. Since the phenomenon is independent of immune complexes, complement, ADP, and kinins, it appears to represent a new mechanism of microbial injury of platelets and the induction of thrombocytopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207622"} {"pmid": "4207623", "title": "A serum factor in chronic hypocomplementemic hephritis distinct from immunoglobulins and activating the alternate pathway of complement.", "content": "A serum factor in chronic hypocomplementemic hephritis distinct from immunoglobulins and activating the alternate pathway of complement. Nephritic factor (C3NeF) has been isolated from plasma of patients with hypocomplementemic chronic glomerulonephritis (HCG) by ion exchange and molecular sieve chromatography. This material was further treated with solidified anti-Ig antiserum. The purified material failed to react with antiserum to human IgG, IgG3, Fab, Fc, and kappa and lambda chains, but retained full C3NeF activity. The nonidentity of C3NeF with IgG was further demonstrated by Ouchterlony analysis using anti-IgG and anti-C3NeF. Isolated C3NeF was found to be a protein with a sedimentation coefficient of 7S and a mol wt of 150,000 daltons, which on microzone electrophoresis and gel electrophoresis at pH 8.6 behaved as a gamma-globulin. C3NeF is not a C1q precipitin and does not activate the classical complement pathway. Unlike cobra venom factor, it failed to enter into a complex with C3 proactivator (C3PA) when incubated with normal human serum (NHS) and then subjected to sucrose density gradient ultracentrifugation. The action of isolated C3NeF on C3 requires C3PA, C3PA convertase (C3PAse), and properdin (P). Similarly, C3PA conversion by C3NeF requires P, C3PAse, and C3. Total hemolytic activity was lost by incubation of 64 microg of C3NeF/1 ml NHS at 37 degrees C for 30 min. Both C3a and C5a anaphylatoxin could be generated by C3NeF in serum previously depleted of anaphylatoxin inactivator. Anti-C3NeF was found to detect an antigen in all NHS tested. Treatment of NHS with solidified anti-C3NeF caused impairment of the alternate complement pathway. It failed to sustain lysis of glutathione-treated human erythrocytes initiated by inulin. It is conceivable that the normal serum constituent which is removed by anti-C3NeF constitutes the inactive precursor of C3NeF, and a heretofore unrecognized component of the alternate pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207623"} {"pmid": "4207627", "title": "Live, attenuated Yersinia pestis vaccine: virulent in nonhuman primates, harmless to guinea pigs.", "content": "Live, attenuated Yersinia pestis vaccine: virulent in nonhuman primates, harmless to guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207627"} {"pmid": "4207631", "title": "Comparative virulence of Nosema plodiae and Nosema heterosporum in the Indian meal moth, Plodia interpunctella.", "content": "Comparative virulence of Nosema plodiae and Nosema heterosporum in the Indian meal moth, Plodia interpunctella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207631"} {"pmid": "4207626", "title": "Comparison of the immune response to three different Yersinia pestis vaccines in guinea pigs and langurs.", "content": "Comparison of the immune response to three different Yersinia pestis vaccines in guinea pigs and langurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207626"} {"pmid": "4207620", "title": "Isolation and characterization of an abnormal human intrinsic factor.", "content": "Isolation and characterization of an abnormal human intrinsic factor. A patient has been described previously who presented at age 13 with vitamin B(12) (B(12)) deficiency secondary to a functionally abnormal intrinsic factor (IF). IF has now been isolated from the gastric juice of the patient, his sister, and both parents, who are first cousins, by using affinity chromatography on B(12)-Sepharose. Patient IF appeared normal in terms of (a) B(12) binding, (b) mol wt, (c) total amino acid and carbohydrate composition, and (d) immunodiffusion with rabbit anti-patient and anti-normal IF sera. After adsorption with normal IF, however, anti-patient IF serum precipitated the various IFs as follows: patient IF (> 95%); mother, father, and sister IF (50%); and normal IF (< 10%). Additional adsorption with mother, father, or sister IF completely inhibited the precipitation of patient IF. The association constant determined for patient IF-B(12) and human ileal mucosal homogenates (0.1 x 10(9) M(-1)) was 60-fold lower than that determined with normal IF-B(12) (6.0 x 10(9) M(-1)). Intermediate amounts of ileal IF-B(12) binding were observed with mother, father, and sister IF-B(12). These in vitro studies were supported by multiple Schilling tests, performed with a totally gastrectomized volunteer, that gave the following mean urinary excretions of [(57)Co]B(12): free B(12) (0.5%); + patient gastric juice (2.6%); + mother or father gastric juice (17%); and + normal gastric juice (26%). These studies demonstrate that the patient is homozygous and that the mother, father, and sister are heterozygous for a structurally abnormal IF that has a markedly decreased, but not absent, affinity for ileal IF-B(12) receptors. These studies also indicate that the B(12) and ileal binding sites are located on different portions of the IF molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207620"} {"pmid": "4207632", "title": "Occurrence of a haplosporidian in native oysters (Ostrea lurida) from Yaquina bay and Alsea bay, Oregon.", "content": "Occurrence of a haplosporidian in native oysters (Ostrea lurida) from Yaquina bay and Alsea bay, Oregon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207632"} {"pmid": "4207621", "title": "Development of cellular and humoral immunity in the respiratory tract of rabbits to Pseudomonas lipopolysaccharide.", "content": "Development of cellular and humoral immunity in the respiratory tract of rabbits to Pseudomonas lipopolysaccharide. Immunization with Pseudomonas lipopolysaccharide induced both cellular and humoral immunity in rabbits, particularly in the respiratory tract after intranasal immunization. Either parenteral (i.m.) or intranasal immunization elicited an IgG antibody response in respiratory secretions, but only intranasal immunization produced secretory IgA antibody. Immunization by both routes stimulated serum IgM and IgG agglutinative antibodies. Because both methods of immunization produced skin test reactivity which had components of both Arthus and tuberculin-like reactions, cellular immunity was more readily assessed by the measurement of migration inhibitory factor (MIF) released from immune lymphocytes in respiratory and spleen cell suspensions after challenge with the lipopolysaccharide antigen. After intranasal vaccination, MIF activity was detected in the respiratory tract by direct assay; in contrast, i.m. immunized rabbits did not produce respiratory MIF. Both modes of immunization resulted in splenic MIF activity. However, lymphocytes were only capable of producing MIF for short periods after primary immunization had ended, apparently losing this function in about 2-3 wk. Therefore, it was concluded that cellular immunity by in vitro assay was transient after primary immunization with this Pseudomonas antigen in contrast to the more persistent humoral immunity. The biological significance of immune lymphocytes as part of the coordinated host defense of the lung needs further evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207621"} {"pmid": "4207635", "title": "Marburg virus disease.", "content": "Marburg virus disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207635"} {"pmid": "4207634", "title": "Lead encephalopathy. Report of a case associated with industrial exposure.", "content": "Lead encephalopathy. Report of a case associated with industrial exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207634"} {"pmid": "4207636", "title": "The vaccination of man and other animals against rabies.", "content": "The vaccination of man and other animals against rabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207636"} {"pmid": "4207640", "title": "Metabolic controls in precancerous liver. V. Loss of control of cholesterol synthesis during feeding of the hepatocarcinogen 3'-methyl-4-dimethylaminoazobenzene.", "content": "Metabolic controls in precancerous liver. V. Loss of control of cholesterol synthesis during feeding of the hepatocarcinogen 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207640"} {"pmid": "4207639", "title": "Visualization of catalase on acrylamide gels.", "content": "Visualization of catalase on acrylamide gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207639"} {"pmid": "4207642", "title": "The geographic unit as a phase in merging hospital and community programs.", "content": "The geographic unit as a phase in merging hospital and community programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207642"} {"pmid": "4207641", "title": "Experimental digital replantation.", "content": "Experimental digital replantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207641"} {"pmid": "4207605", "title": "Cervical mycobacterial disease.", "content": "Cervical mycobacterial disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207605"} {"pmid": "4207604", "title": "Anatomy and physiology of the optic nerve head.", "content": "Anatomy and physiology of the optic nerve head.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207604"} {"pmid": "4207643", "title": "I. The future role of the state hospital.", "content": "I. The future role of the state hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207643"} {"pmid": "4207644", "title": "3. Where is my home? The closing of state mental hospitals.", "content": "3. Where is my home? The closing of state mental hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207644"} {"pmid": "4207645", "title": "Lethal and genetic effects of radiophosphorus decay in bacteriophages SP82G and T7.", "content": "Lethal and genetic effects of radiophosphorus decay in bacteriophages SP82G and T7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207645"} {"pmid": "4207652", "title": "Electrical activity of the motor cortex associated with voluntary movements in the baboon.", "content": "Electrical activity of the motor cortex associated with voluntary movements in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207652"} {"pmid": "4207651", "title": "The occurrence and possible functional significance of -S-S- crosslinks in sperm heads, with particular reference to eutherian mammals.", "content": "The occurrence and possible functional significance of -S-S- crosslinks in sperm heads, with particular reference to eutherian mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207651"} {"pmid": "4207653", "title": "Remote control system for very small micro-electrode advancens.", "content": "Remote control system for very small micro-electrode advancens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207653"} {"pmid": "4207654", "title": "Emptying the bladder by stimulating sacral ventral roots.", "content": "Emptying the bladder by stimulating sacral ventral roots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207654"} {"pmid": "4207656", "title": "Recording from single-cells in infero-temporal cortex of the monkey during discrimination performance.", "content": "Recording from single-cells in infero-temporal cortex of the monkey during discrimination performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207656"} {"pmid": "4207655", "title": "The role of the carotid body chemoreceptors and carotid sinus baroreceptors in the control of cerebral blood vessels.", "content": "The role of the carotid body chemoreceptors and carotid sinus baroreceptors in the control of cerebral blood vessels. 1. Cerebral blood flow was measured in 17 baboons, anaesthetized with pentobarbitone, paralysed with gallamine and mechanically ventilated and in which the right sinus and both aortic nerves had been cut and the left carotid sinus vascularly isolated. Later in each experiment, the head was artificially perfused with femoral arterial blood via the innominate artery.2. Stimulation of the carotid body chemoreceptors with venous blood invariably caused a rise in regional cerebral blood flow whether the head was naturally or artificially perfused. This response was almost completely abolished if the VIIth cranial nerves were cut intracranially.3. Regional cerebral blood flow varied inversely with carotid sinus pressure.4. After the remaining (left) sinus nerve had been cut, the cerebral vascular response to hypoxia was negligible and the response to hypercapnia was markedly reduced. Blood flow then varied with perfusion pressure.5. These results provide further evidence that cerebral blood vessels are reflexly controlled and that the peripheral arterial receptors are involved. Their action is most conspicuous in the vascular response to hypoxia and together with intrinsic factors in the cerebral vascular bed, they determine the size of the vascular response to changes in CO(2) and pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207655"} {"pmid": "4207648", "title": "What are comprehensive health services?", "content": "What are comprehensive health services?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207648"} {"pmid": "4207657", "title": "The rapid achievement and maintenance of a steady level of an injected substance in the blood plasma.", "content": "The rapid achievement and maintenance of a steady level of an injected substance in the blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207657"} {"pmid": "4207649", "title": "Priorities and decision making in health planning.", "content": "Priorities and decision making in health planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207649"} {"pmid": "4207658", "title": "The compliance of contracting skeletal muscle.", "content": "The compliance of contracting skeletal muscle. 1. The method of controlled releases was used to obtain tension-extension curves in toad (Bufo bufo) sartorii under a variety of conditions at 0 degrees C.2. The curves obtained were approximately linear over a considerable range of force (0.4P(0) to P(0)) if the releases were given from the plateau of tetanic tension. The slope of this linear region was little affected by changes of release velocity in the range 10-120 mm/sec.3. Such changes as did occur with alterations in release velocity could be quantitatively accounted for in terms of the internal shortening predicted by A. V. Hill's two-component model.4. As the muscles were stretched above l(0), we found that the maximum stiffness of the tetanized muscles fell in much the same way as the maximum developed force, P(0).5. In another series of experiments we found a rapid change in the overall shape of the tension-extension curve during the early phase of force development in an isometric tetanus. The stiffness of the muscle increased with increasing developed force during this period.6. The force-velocity curve in these muscles was measured by two methods, both giving a similar result. Surprisingly, toad muscle appears to have about the same intrinsic speed as frog muscle at 0 degrees C. The a.b product from our experiments is considerably greater than the reported values for the maintenance heat rate at 0 degrees C in these muscles.7. The probable site of the variable compliance in active muscle is discussed. It seems most likely that this is within the A-band, perhaps in the cross-bridges themselves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207658"} {"pmid": "4207650", "title": "The scope and bounds of health economics and medical economics.", "content": "The scope and bounds of health economics and medical economics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207650"} {"pmid": "4207647", "title": "Is there a future for family medicine?", "content": "Is there a future for family medicine?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207647"} {"pmid": "4207646", "title": "Maximum and optimum in health services.", "content": "Maximum and optimum in health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207646"} {"pmid": "4207691", "title": "Dopa metabolism by Mycobacterium leprae: its implications in culture of the bacillus and chemotherapy of leprosy.", "content": "Dopa metabolism by Mycobacterium leprae: its implications in culture of the bacillus and chemotherapy of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207691"} {"pmid": "4207693", "title": "Population genetics of modifiers of meiotic drive. II. Linkage modification in the segregation distortion system.", "content": "Population genetics of modifiers of meiotic drive. II. Linkage modification in the segregation distortion system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207693"} {"pmid": "4207692", "title": "Structure and function of plant microbodies.", "content": "Structure and function of plant microbodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207692"} {"pmid": "4207694", "title": "Use of 18F labelled fluorocarbon-11 to investigate the fate of inhaled fluorocarbons in man and in the rat.", "content": "Use of 18F labelled fluorocarbon-11 to investigate the fate of inhaled fluorocarbons in man and in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207694"} {"pmid": "4207696", "title": "Thyroid function through pregnancy and in the fetus and newly born from a goiter endemic in Peru.", "content": "Thyroid function through pregnancy and in the fetus and newly born from a goiter endemic in Peru.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207696"} {"pmid": "4207698", "title": "Total serum T3 and TSH response to TRH stimulation in patients with endemic goiter.", "content": "Total serum T3 and TSH response to TRH stimulation in patients with endemic goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207698"} {"pmid": "4207697", "title": "TSH response to synthetic TRH in endemic goitre.", "content": "TSH response to synthetic TRH in endemic goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207697"} {"pmid": "4207699", "title": "Some aspects of humoral immunologic reactivity in habitual abortion. (Assay of antitrophoblast IgG, IgA, and IgM by radial immunodiffusion: relationship with leukocyte agglutinating antibodies).", "content": "Some aspects of humoral immunologic reactivity in habitual abortion. (Assay of antitrophoblast IgG, IgA, and IgM by radial immunodiffusion: relationship with leukocyte agglutinating antibodies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207699"} {"pmid": "4207701", "title": "Arginosuccinicaciduria. The hair abnormality.", "content": "Arginosuccinicaciduria. The hair abnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207701"} {"pmid": "4207700", "title": "Hemolytic uremic syndrome associated with infectious mononucleosis.", "content": "Hemolytic uremic syndrome associated with infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207700"} {"pmid": "4207702", "title": "Congestive heart failure secondary to idiopathic hypoparathyroidism.", "content": "Congestive heart failure secondary to idiopathic hypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207702"} {"pmid": "4207703", "title": "On the thermodynamics of cell injury. Some insights into the molecular mechanisms.", "content": "On the thermodynamics of cell injury. Some insights into the molecular mechanisms. A method is presented for determining the thermodynamic parameters of the rate-limiting chemical reaction in cell injury. From these parameters one can deduce certain molecular details of this reaction, such as the number of molecular events required for a specific observable injury, the approximate number of the chemical bonds broken and the degree of molecular configurational change involved. Inactivation of cell division in vitro by heat and by an alkylating agent have been studied by this method. In each case cell injury involved only one to three catastrophic molecular events, which were irreparable within a 3-day period. This suggests that in each case there had been an alteration of a genome essential for cell division. In the case of thermal injury this critical molecular event had the thermodynamic characteristics of a massive configurational change, compatible with the uncoiling of a DNA segment. In the case of alkylation injury the thermodynamic parameters were those of a small localized event with little configurational change and energetically compatible with an alkylation-depurination of DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207703"} {"pmid": "4207705", "title": "Aspects of dependency.", "content": "Aspects of dependency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207705"} {"pmid": "4207706", "title": "Bacterial degradation of cyclohexane. Participation of a co-oxidation reaction.", "content": "Bacterial degradation of cyclohexane. Participation of a co-oxidation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207706"} {"pmid": "4207707", "title": "Comparison of an oral and an intravenous feeding regimen in the newborn.", "content": "Comparison of an oral and an intravenous feeding regimen in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207707"} {"pmid": "4207708", "title": "Serum levels of immune globulins in postmaturity.", "content": "Serum levels of immune globulins in postmaturity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207708"} {"pmid": "4207709", "title": "Thyroid status in the newborn infant. Effective thyroxine ratio and free thyroxine index.", "content": "Thyroid status in the newborn infant. Effective thyroxine ratio and free thyroxine index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207709"} {"pmid": "4207710", "title": "Proceedings: Problems encountered in design of diets for treatment of protein energy malnutrition.", "content": "Proceedings: Problems encountered in design of diets for treatment of protein energy malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207710"} {"pmid": "4207711", "title": "L-threonine deaminase in marine planktonic algae. IV. Studies of substrate specificity and inhibition from substrate analogs. Evidence for additional L-serine deaminase activity in the cryptophyte Chroomonas salina.", "content": "L-threonine deaminase in marine planktonic algae. IV. Studies of substrate specificity and inhibition from substrate analogs. Evidence for additional L-serine deaminase activity in the cryptophyte Chroomonas salina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207711"} {"pmid": "4207704", "title": "Recently defined onco-fetal antigens and their potential application in clinical medicine.", "content": "Recently defined onco-fetal antigens and their potential application in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207704"} {"pmid": "4207716", "title": "Autoimmunity and the retina. II. Raised serum IgM levels in retinitis pigmentosa.", "content": "Autoimmunity and the retina. II. Raised serum IgM levels in retinitis pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207716"} {"pmid": "4207715", "title": "Immunoglobulins in aqueous humour and iris from patients with endogenous uveitis and patients with cataract.", "content": "Immunoglobulins in aqueous humour and iris from patients with endogenous uveitis and patients with cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207715"} {"pmid": "4207718", "title": "Differential activity of prefrontal units during right and left delayed response trials.", "content": "Differential activity of prefrontal units during right and left delayed response trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207718"} {"pmid": "4207717", "title": "Effects of papaverine on the retinal microcirculation.", "content": "Effects of papaverine on the retinal microcirculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207717"} {"pmid": "4207713", "title": "Hemophilus influenzae septic arthritis. A mimicker of gonococcal arthritis.", "content": "Hemophilus influenzae septic arthritis. A mimicker of gonococcal arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207713"} {"pmid": "4207719", "title": "Binding of thymus histone F1 and E. coli RNA polymerase to DNA of polytene chromosomes of Drosophila.", "content": "Binding of thymus histone F1 and E. coli RNA polymerase to DNA of polytene chromosomes of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207719"} {"pmid": "4207720", "title": "Different DNA replication behavior of a tandem duplication in Drosophila melanogaster.", "content": "Different DNA replication behavior of a tandem duplication in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207720"} {"pmid": "4207723", "title": "Characterization of the soluble proteins from rabbit eye lens.", "content": "Characterization of the soluble proteins from rabbit eye lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207723"} {"pmid": "4207712", "title": "Bacteriolytic and bactericidal activity of sera and synovial fluids in rheumatoid arthritis and in osteoarthritis.", "content": "Bacteriolytic and bactericidal activity of sera and synovial fluids in rheumatoid arthritis and in osteoarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207712"} {"pmid": "4207724", "title": "Single cell activity in the ventral lateral thalamus of the unanesthetized monkey.", "content": "Single cell activity in the ventral lateral thalamus of the unanesthetized monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207724"} {"pmid": "4207714", "title": "Proceedings: Quinidine induced lupus erythematosus.", "content": "Proceedings: Quinidine induced lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207714"} {"pmid": "4207725", "title": "Preservation of cutaneous temperature sensitivity after ablation of sensory cortex in monkeys.", "content": "Preservation of cutaneous temperature sensitivity after ablation of sensory cortex in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207725"} {"pmid": "4207726", "title": "Regional cerebral blood flow of the main visual pathways during photic stimulation of the retina in intact and split-brain monkeys.", "content": "Regional cerebral blood flow of the main visual pathways during photic stimulation of the retina in intact and split-brain monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207726"} {"pmid": "4207721", "title": "Pseudomonas osteomyelitis of the metatarsal sesamoid of the great toe.", "content": "Pseudomonas osteomyelitis of the metatarsal sesamoid of the great toe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207721"} {"pmid": "4207728", "title": "Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species.", "content": "Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207728"} {"pmid": "4207729", "title": "Leukemia virus-induced immunosuppression. X. Depression of T cell-mediated cytotoxicity after infection of mice with Friend leukemia virus.", "content": "Leukemia virus-induced immunosuppression. X. Depression of T cell-mediated cytotoxicity after infection of mice with Friend leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207729"} {"pmid": "4207722", "title": "Salmonella Paratyphi osteomyelitis. Report of a case simulating a giant cell tumor.", "content": "Salmonella Paratyphi osteomyelitis. Report of a case simulating a giant cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207722"} {"pmid": "4207730", "title": "Interaction of rheumatoid factor with infectious vaccinia virus-antibody complexes.", "content": "Interaction of rheumatoid factor with infectious vaccinia virus-antibody complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207730"} {"pmid": "4207731", "title": "Sites of localization and synthesis of Ss protein in mice.", "content": "Sites of localization and synthesis of Ss protein in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207731"} {"pmid": "4207732", "title": "The binding of alpha-1 antitrypsin to human IgA.", "content": "The binding of alpha-1 antitrypsin to human IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207732"} {"pmid": "4207733", "title": "Subclavian vein catheterization in the infant.", "content": "Subclavian vein catheterization in the infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207733"} {"pmid": "4207734", "title": "Traumatic prevertebral pharyngoesophageal pseudodiverticulum in the newborn infant.", "content": "Traumatic prevertebral pharyngoesophageal pseudodiverticulum in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207734"} {"pmid": "4207737", "title": "Morphogenesis of wheat striate mosaic virus--the internal nucleoprotein component.", "content": "Morphogenesis of wheat striate mosaic virus--the internal nucleoprotein component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207737"} {"pmid": "4207736", "title": "Urethral diverticulum: complication of abdominoperineal pull-through procedure.", "content": "Urethral diverticulum: complication of abdominoperineal pull-through procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207736"} {"pmid": "4207739", "title": "Letter: Primary structure of tuberculin-active protein from tubercule bacilli.", "content": "Letter: Primary structure of tuberculin-active protein from tubercule bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207739"} {"pmid": "4207735", "title": "Traumatic perforation of the pharynx in a newborn baby.", "content": "Traumatic perforation of the pharynx in a newborn baby.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207735"} {"pmid": "4207740", "title": "Serological typing of Pseudomonas aeruginosa and several points to be considered.", "content": "Serological typing of Pseudomonas aeruginosa and several points to be considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207740"} {"pmid": "4207741", "title": "Cell proliferation in mouse kidney induced by lead. I. Synthesis of deoxyribonucleic acid.", "content": "Cell proliferation in mouse kidney induced by lead. I. Synthesis of deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207741"} {"pmid": "4207742", "title": "The use of contrast enemas in the diagnosis of neonatal intestinal obstruction.", "content": "The use of contrast enemas in the diagnosis of neonatal intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207742"} {"pmid": "4207745", "title": "Specificity of antibodies to the modified DNA of phages SPO1 and T4.", "content": "Specificity of antibodies to the modified DNA of phages SPO1 and T4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207745"} {"pmid": "4207744", "title": "The mechanism of transfection. Kinetics and nature of B. subtilis transfection by phage SP-50 desoxyribonucleic acid.", "content": "The mechanism of transfection. Kinetics and nature of B. subtilis transfection by phage SP-50 desoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207744"} {"pmid": "4207743", "title": "Acute arthritis caused by gram-negative bacilli: a clinical characterization.", "content": "Acute arthritis caused by gram-negative bacilli: a clinical characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207743"} {"pmid": "4207746", "title": "The addition of proteins carrying fluorochrome to polytene chromosomes of Drosophila.", "content": "The addition of proteins carrying fluorochrome to polytene chromosomes of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207746"} {"pmid": "4207747", "title": "Letter: Multiple sclerosis and diseased sheep brain.", "content": "Letter: Multiple sclerosis and diseased sheep brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207747"} {"pmid": "4207748", "title": "A complex cerebral vascular malformation studied by angiography; multiple aneurysms angiomas and arterial ectasia.", "content": "A complex cerebral vascular malformation studied by angiography; multiple aneurysms angiomas and arterial ectasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207748"} {"pmid": "4207749", "title": "Turkey leucocytozoon infection. 3. Ultrastructure of Leucocytozoon smithi gametocytes.", "content": "Turkey leucocytozoon infection. 3. Ultrastructure of Leucocytozoon smithi gametocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207749"} {"pmid": "4207750", "title": "Bone ash and duodenal calcium-binding protein in chicks treated with EHDP.", "content": "Bone ash and duodenal calcium-binding protein in chicks treated with EHDP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207750"} {"pmid": "4207753", "title": "Outpatient screening for gastrointestinal lesions using guaiac-impregnated slides.", "content": "Outpatient screening for gastrointestinal lesions using guaiac-impregnated slides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207753"} {"pmid": "4207754", "title": "Effect of administered human growth hormone on growth retardation in inflammatory bowel disease.", "content": "Effect of administered human growth hormone on growth retardation in inflammatory bowel disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207754"} {"pmid": "4207755", "title": "Activity of lividomycin against Pseudomonas aeruginosa: its inactivation by phosphorylation induced by resistant strains.", "content": "Activity of lividomycin against Pseudomonas aeruginosa: its inactivation by phosphorylation induced by resistant strains. The antibacterial activity and enzymatic inactivation of lividomycin, a new aminoglycosidic antibiotic, were studied with 13 strains of Pseudomonas aeruginosa. The minimal inhibitory concentration of lividomycin was 12.5 to 25 mug/ml, and three strains were resistant to high concentrations of lividomycin (more than 200 mug/ml). It was found that P. aeruginosa TI-13 and K-11, highly lividomycin-resistant strains of clinical origin, strongly inactivated the drug. The third resistant strain, Km-41/R, was developed in vitro. Unlike the other resistant strains, Km-41/R, was developed in vitro. Unlike the other resistant strains, Km-41/R did not inactivate the drug, indicating that different mechanisms were involved in lividomycin resistance. By use of a cell-free extract from P. aeruginosa TI-13, the inactivation of lividomycin was found to be caused by the formation of a monophosphorylated product of the drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207755"} {"pmid": "4207756", "title": "Transferable drug resistance in Pseudomonas aeruginosa.", "content": "Transferable drug resistance in Pseudomonas aeruginosa. Three strains of Pseudomonas aeruginosa were demonstrated to transfer double-drug resistance by conjugation to a P. aeruginosa recipient at frequencies of 10(-4) to 10(-2) per recipient cell. Two of the three strains also transferred to Escherichia coli at frequencies which were 10(3)- to 10(5)-fold lower, but the third strain could not be demonstrated to do so. The latter strain, however, conferred maleness on the Pseudomonas recipient. The transfer of streptomycin resistance was associated with the acquisition of streptomycin phosphorylase by both P. aeruginosa and E. coli recipients. Maximal broth mating frequencies were obtained with nonagitated cultures less than 1 mm in depth. A pyocine selection system based on donor sensitivity and recipient resistance is described and appears to have future value as a generalized selective device for use after matings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207756"} {"pmid": "4207757", "title": "Antibiotic synergism against Listeria monocytogenes.", "content": "Antibiotic synergism against Listeria monocytogenes. The effectiveness of ampicillin, penicillin, streptomycin, and gentamicin against 20 strains of Listeria monocytogenes was studied in vitro. For all strains, the minimal bactericidal concentration (MBC) of both ampicillin and penicillin was much higher than the minimal inhibitory concentration (MIC). The MBC of both streptomycin and gentamicin was close to the MIC, but relatively high concentrations of these antibiotics were necessary to inhibit the growth of most of the strains of Listeria. The combination of penicillin plus streptomycin was synergistic against 19 of 20 strains and in the remaining strain produced enhanced killing (but of less magnitude than our criterion for synergism). Combinations of penicillin plus gentamicin, ampicillin plus streptomycin, and ampicillin plus gentamicin produced enhanced killing against all strains tested. No antagonism was observed when ampicillin or penicillin was combined with streptomycin or gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207757"} {"pmid": "4207758", "title": "Activity of two chlorinated lincomycin analogues against chloroquine-resistant falciparum malaria in owl monkeys.", "content": "Activity of two chlorinated lincomycin analogues against chloroquine-resistant falciparum malaria in owl monkeys. The chloroquine-resistant Oak Knoll strain of Plasmodium falciparum, recently adapted to the owl monkey (Aotus trivirgatus), was insusceptible to chloroquine therapy. Two chlorinated lincomycin analogues tested in this host-parasite system cured blood-induced infections. Acute infections were treated orally for 7 consecutive days with either 15 or 75 mg of clindamycin hydrochloride (U-21) per kg per day, 10 or 50 mg of N-demethyl-4'-pentyl clindamycin hydrochloride (U-24) per kg per day, or 20 mg of chloroquine base per kg per day. These lincomycin analogues cleared trophozoites from the peripheral blood by the end of the 7-day treatment period. The speed of clearance of parasites was not dose-related, but curative activity appeared dependent upon the amount of drug given as well as the number of daily treatments. The efficacy of U-21 and U-24 is of particular interest since they represent major structural departures from compounds commonly used in the treatment of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207758"} {"pmid": "4207759", "title": "Relationship between the uptake of isoniazid and its action on in vivo mycolic acid synthesis in Mycobacterium tuberculosis.", "content": "Relationship between the uptake of isoniazid and its action on in vivo mycolic acid synthesis in Mycobacterium tuberculosis. A direct relationship was established between the rate of uptake of isoniazid and the action of this drug on in vivo mycolic acid synthesis in Mycobacterium tuberculosis H37Ra. The rate of uptake of isoniazid increased linearly with its external concentration and appeared to reach a maximal value of 52 pmoles per hr per 10(9) cells at an external concentration of about 13 mum. Correspondingly, the rate of inhibition of mycolic acid synthesis increased with the rise in the rate of uptake of the drug. A 50% inhibition of mycolic acid synthesis occurred when the uptake of isoniazid reached 5.2 pmoles per 10(9) cells. Calculations showed that this level of drug uptake represents an internal cellular concentration of 9 mum. These results show clearly that the action of isoniazid on the mycolate synthetase system of M. tuberculosis is rapid and that this enzyme system is highly sensitive to the drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207759"} {"pmid": "4207760", "title": "Immunochemical studies on lipopolysaccharide from agglutinable and non-agglutinable vibrios.", "content": "Immunochemical studies on lipopolysaccharide from agglutinable and non-agglutinable vibrios. Lipopolysaccharide (LPS) prepared from Vibrio cholerae and a non-agglutinable (NAG; not agglutinable with O-group I serum according to Gardner and Venkatraman [13]) vibrio strain, isolated from a patient with cholera-like clinical symptoms, have been compared with respect to their chemical composition and immunological behavior. In addition to a significant difference in the chemical composition between the two lipopolysaccharides, the LPS from V. cholerae, unlike that from the NAG vibrio, requires prior treatment with alkali for it to be an effective antigen in the indirect hemagglutination test with sheep cells. It has been suggested that the alkali acts by removing excess O-acetyl group from LPS of agglutinable vibrios. LPS from the NAG vibrio consistently showed a lower antibody response in rabbits in terms of agglutinin and vibriocidal titer. Also, the class of agglutinin antibody elicited by LPS of the NAG vibrio was predominantly immunoglobin M, and that from V. cholerae was immunoglobulin G under comparable conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207760"} {"pmid": "4207761", "title": "Some factors affecting the viability of dried bacteria during storage in vacuo.", "content": "Some factors affecting the viability of dried bacteria during storage in vacuo. The effects of various substances on the viability of freeze-dried cells of Pseudomonas fluorescens and Salmonella newport were studied during storage in vacuo for 5 years. Mixtures of two organisms were dried together and studied in two factorial experiments. The first was a complete factorial using six factors and two levels; the second was a fractional replicate with four factors at two levels and three others at four concentrations. A study of ribose binding by cells of S. newport was made by using [U-(14)C]ribose. Substantial improvements in viability were obtained by drying in the presence of sucrose, glutamate, and semicarbazide. Low concentrations of ribose increased the death rate during drying, but these adverse effects were prevented by equimolar amounts of semicarbazide. Ribose binding increased with storage time and, although its incorporation changed, most of the increase in total ribose occurred after the main decrease in viability. Storage temperature caused larger changes in viability than did level changes of residual water in the cells. Although the results are complicated by a large number of interactions, they confirm and extend the hypothesis that reactions between carbonyl compounds and cellular components are a major cause of the mortality occurring during storage of dried microorganisms. A particular mixture of sucrose, glutamate, and semicarbazide is proposed as a means of reducing death when prolonged storage in the dry state is desired.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207761"} {"pmid": "4207762", "title": "Comparative denitrification of selected microorganisms in a culture medium and in autoclaved soil.", "content": "Comparative denitrification of selected microorganisms in a culture medium and in autoclaved soil. The denitrifying behavior of selected soil bacteria was compared in a culture solution and in soil that was sterilized by autoclaving. The essential characteristics concerning nitrate reduction and the formation of nitrogenous gases did not change significantly for most bacteria in the two environments. Bacteria whose denitrification product was nitrous oxide evolved the same gas both in soil and in a liquid system, whereas other bacteria formed only nitrogen gas. The validity of laboratory observations in relation to field studies in the domain of denitrification is discussed and evaluated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207762"} {"pmid": "4207763", "title": "Stomach fermentation in East African Colobus monkeys in their natural state.", "content": "Stomach fermentation in East African Colobus monkeys in their natural state. The microbial fermentation in the stomachs of two monkeys, Colobus polykomos, collected in Kenya, was studied. The gas accumulated within the stomach contained H(2) but no CH(4). Volatile fatty acid concentrations were high, but accumulated acid prevented determination of the fermentation rate in untreated, incubated stomach contents. Upon addition of bicarbonate, a very rapid rate could be demonstrated. Some D- and L-lactate were in the stomach contents. Starchy seeds or fruits rather than leaves appeared to have been consumed. Microscopically, the most prominent microorganisms seen were large, very refringent cocci, possibly Sarcina ventriculi, and various smaller cocci and rods. The 28 cultured strains of bacteria included 14 Staphylococcus, 2 Streptococcus, 10 Propionibacterium, and 2 Peptostreptococcus. The culture count constituted 10 to 20% of the direct count. No protozoa or cellulolytic bacteria were found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207763"} {"pmid": "4207764", "title": "New system for cultivation of Neisseria gonorrhoeae.", "content": "New system for cultivation of Neisseria gonorrhoeae. A modified Thayer-Martin medium, containing 2.0% agar, 0.25% dextrose, and 5.0 mug of trimethoprim per ml was compared to Thayer-Martin medium for growth of stock cultures of Neisseria gonorrhoeae and for isolation of N. gonorrhoeae from clinical specimens. Stock cultures and male urethral cultures grew equally well on both media, but the modified Thayer-Martin medium detected 10% more female patients positive for gonococci. A description is given of the use of a citric acid-sodium bicarbonate tablet for generating carbon dioxide in a sealed plastic bag containing a culture plate. Equivalent results were obtained on duplicate plates of 336 cultures and specimens when this procedure was compared with the standard candle jar extinction method of incubation. The tablet and plastic bag system has the advantages of economy, ease of use, and safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207764"} {"pmid": "4207767", "title": "Velocity profiles in the retinal microcirculation.", "content": "Velocity profiles in the retinal microcirculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207767"} {"pmid": "4207765", "title": "Some observations on the propagation of avian infectious bronchitis virus in tissue culture.", "content": "Some observations on the propagation of avian infectious bronchitis virus in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207765"} {"pmid": "4207766", "title": "Agglutination of red blood cells by polyelectrolytes and antibodies.", "content": "Agglutination of red blood cells by polyelectrolytes and antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207766"} {"pmid": "4207769", "title": "Editorial: Acute cavitary histoplasmosis--fact or fiction?", "content": "Editorial: Acute cavitary histoplasmosis--fact or fiction?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207769"} {"pmid": "4207770", "title": "Lower lung field tuberculosis.", "content": "Lower lung field tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207770"} {"pmid": "4207771", "title": "Right coronary arterial spasm causing Prinzmetal's variant angina.", "content": "Right coronary arterial spasm causing Prinzmetal's variant angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207771"} {"pmid": "4207772", "title": "Serotaxonomy of Aotus. A preliminary study.", "content": "Serotaxonomy of Aotus. A preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207772"} {"pmid": "4207774", "title": "Distribution, divergence and speciation of the drill and mandrill.", "content": "Distribution, divergence and speciation of the drill and mandrill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207774"} {"pmid": "4207775", "title": "Parental care in a group of free-ranging rhesus monkeys (Macaca mulatta).", "content": "Parental care in a group of free-ranging rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207775"} {"pmid": "4207776", "title": "Social structure of the squirrel monkey (Saimiri sciureus, Iquitos): relationships among behavior, heartrate, and physical distance.", "content": "Social structure of the squirrel monkey (Saimiri sciureus, Iquitos): relationships among behavior, heartrate, and physical distance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207776"} {"pmid": "4207768", "title": "Two outbreaks of Bacillus cereus food poisoning in Canada.", "content": "Two outbreaks of Bacillus cereus food poisoning in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207768"} {"pmid": "4207777", "title": "Interrelationship of blood groups between rhesus macaques (Macaca mulatta) and Celebes ape (Macaca niger).", "content": "Interrelationship of blood groups between rhesus macaques (Macaca mulatta) and Celebes ape (Macaca niger).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207777"} {"pmid": "4207779", "title": "Immediate surgical repositioning of one- and two-tooth dento-osseous segments.", "content": "Immediate surgical repositioning of one- and two-tooth dento-osseous segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207779"} {"pmid": "4207780", "title": "Prevention of postoperative symptoms by general antibiotic treatment and local bandage in removal of mandibular third molars.", "content": "Prevention of postoperative symptoms by general antibiotic treatment and local bandage in removal of mandibular third molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207780"} {"pmid": "4207781", "title": "Neomycin-bacitracin cones in impacted third molar sockets.", "content": "Neomycin-bacitracin cones in impacted third molar sockets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207781"} {"pmid": "4207782", "title": "Unusual complication following surgically treated fracture of the mandibular condyle.", "content": "Unusual complication following surgically treated fracture of the mandibular condyle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207782"} {"pmid": "4207783", "title": "Fibrosarcoma of the tongue.", "content": "Fibrosarcoma of the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207783"} {"pmid": "4207784", "title": "The evaluation of ankle pathology with arthrography.", "content": "The evaluation of ankle pathology with arthrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207784"} {"pmid": "4207785", "title": "M-81, a new peptide antibiotic produced by Streptomyces griseus subsp. Psychrophilus at moderate temperature.", "content": "M-81, a new peptide antibiotic produced by Streptomyces griseus subsp. Psychrophilus at moderate temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207785"} {"pmid": "4207786", "title": "On the mode of action of hodydamycin.", "content": "On the mode of action of hodydamycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207786"} {"pmid": "4207787", "title": "Cryomycin and M-81 production from hexamethylenediamine.", "content": "Cryomycin and M-81 production from hexamethylenediamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207787"} {"pmid": "4207788", "title": "New metabolic products of Aspergillus flavus. IV. 4'-Hydroxyasperentin and 5'-hydroxyasperentin 8-methyl ether.", "content": "New metabolic products of Aspergillus flavus. IV. 4'-Hydroxyasperentin and 5'-hydroxyasperentin 8-methyl ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207788"} {"pmid": "4207789", "title": "Cytological evidence for catecholamine-containing sensory cells bordering the ventricle of the toad hypothalamus.", "content": "Cytological evidence for catecholamine-containing sensory cells bordering the ventricle of the toad hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207789"} {"pmid": "4207790", "title": "Antibodies to sperms and seminal plasma in infertile couples.", "content": "Antibodies to sperms and seminal plasma in infertile couples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207790"} {"pmid": "4207791", "title": "Comparison of three serological methods for the detection of hepatitis-associated antigen.", "content": "Comparison of three serological methods for the detection of hepatitis-associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207791"} {"pmid": "4207792", "title": "Laboratory aspects of gonorrhea control. II.", "content": "Laboratory aspects of gonorrhea control. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207792"} {"pmid": "4207793", "title": "Replacement of functional parenchymal cells by fat and connective tissue in human submandibular salivary glands: an age-related change.", "content": "Replacement of functional parenchymal cells by fat and connective tissue in human submandibular salivary glands: an age-related change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207793"} {"pmid": "4207794", "title": "Total body irradiation effects on the bone resorption mechanism in rats subjected to orthodontic movements.", "content": "Total body irradiation effects on the bone resorption mechanism in rats subjected to orthodontic movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207794"} {"pmid": "4207795", "title": "A comparative assay of the in-vitro and in-vivo behavior of three chemically induced neoplasms of rat submandibular glands.", "content": "A comparative assay of the in-vitro and in-vivo behavior of three chemically induced neoplasms of rat submandibular glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207795"} {"pmid": "4207796", "title": "Observations on the ultrastructure of the epithelium in oral lichen planus.", "content": "Observations on the ultrastructure of the epithelium in oral lichen planus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207796"} {"pmid": "4207797", "title": "The experimental production of odontogenic keratocysts.", "content": "The experimental production of odontogenic keratocysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207797"} {"pmid": "4207798", "title": "Electron microscopy of enamel surface after reactions of apatite accretion.", "content": "Electron microscopy of enamel surface after reactions of apatite accretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207798"} {"pmid": "4207799", "title": "The acquired pellicle: variability and subject-dependence of specific proteins.", "content": "The acquired pellicle: variability and subject-dependence of specific proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207799"} {"pmid": "4207800", "title": "The immunology of cancer.", "content": "The immunology of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207800"} {"pmid": "4207801", "title": "Microradiographic study of human temporomandibular disks obtained at autopsy.", "content": "Microradiographic study of human temporomandibular disks obtained at autopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207801"} {"pmid": "4207808", "title": "Defensive use by an insect of a plant resin.", "content": "Defensive use by an insect of a plant resin. Larvae of the sawfly Neodiprion sertifer (Hymenoptera: Diprionidae), when disturbed, discharge an oily oral effluent essentially identical chemically to the terpenoid resin of its host plant (Pinus sylvestris). The resin is sequestered by the larva upon feeding, and stored in two compressible diverticular pouches of the foregut. The fluid is effectively deterrent to predators. The defensive use by an insect of a plant resin provides an instance of secondary utilization by a herbivore of the protective chemical weaponry of its host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207808"} {"pmid": "4207810", "title": "Medical Grand Rounds: from the Department of Medicine, University of Virginia Medical Center. Meningococcal meningitis and meningococcemia.", "content": "Medical Grand Rounds: from the Department of Medicine, University of Virginia Medical Center. Meningococcal meningitis and meningococcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207810"} {"pmid": "4207811", "title": "A note on the susceptibility of sheep and goats to East Coast fever.", "content": "A note on the susceptibility of sheep and goats to East Coast fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207811"} {"pmid": "4207815", "title": "Timely topics in microbiology, 1972: gram positive.", "content": "Timely topics in microbiology, 1972: gram positive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207815"} {"pmid": "4207816", "title": "Results and problems of O-Glycoside synthesis.", "content": "Results and problems of O-Glycoside synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207816"} {"pmid": "4207817", "title": "Recent discoveries in the evolution of protein.", "content": "Recent discoveries in the evolution of protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207817"} {"pmid": "4207830", "title": "The effects of prefrontal lobotomy on aggressive behavior in dogs.", "content": "The effects of prefrontal lobotomy on aggressive behavior in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207830"} {"pmid": "4207831", "title": "Mycoplasma bovigenitalium: experimental induction of genital disease in bulls.", "content": "Mycoplasma bovigenitalium: experimental induction of genital disease in bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207831"} {"pmid": "4207832", "title": "Hepatitis associated antigen in blood donors in Ethiopia.", "content": "Hepatitis associated antigen in blood donors in Ethiopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207832"} {"pmid": "4207834", "title": "Rumen microbial numbers in lambs as affected by level of feed intake and dietary diethylstilestrol.", "content": "Rumen microbial numbers in lambs as affected by level of feed intake and dietary diethylstilestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207834"} {"pmid": "4207836", "title": "Intraluminal diverticulum of the duodenum: report of a case with roentgenologic and endoscopic appearance.", "content": "Intraluminal diverticulum of the duodenum: report of a case with roentgenologic and endoscopic appearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207836"} {"pmid": "4207835", "title": "Regional circulatory adjustments to eating and digestion in conscious unrestrained primates.", "content": "Regional circulatory adjustments to eating and digestion in conscious unrestrained primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207835"} {"pmid": "4207849", "title": "Contributions to the optimal use of human blood. 3. Large-scale preparation of human c1 esterase inhibitor concentrate for clinical use.", "content": "Contributions to the optimal use of human blood. 3. Large-scale preparation of human c1 esterase inhibitor concentrate for clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207849"} {"pmid": "4207850", "title": "An international proficiency survey for the detection of hepatitis B antigen and antibody in blood donations by counterimmunoelectrophoresis.", "content": "An international proficiency survey for the detection of hepatitis B antigen and antibody in blood donations by counterimmunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207850"} {"pmid": "4207851", "title": "Presence of chronic lymphoid leukaemia associated antigen in other malignant haematological diseases.", "content": "Presence of chronic lymphoid leukaemia associated antigen in other malignant haematological diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207851"} {"pmid": "4207857", "title": "Sexual differences in the anterior dentition in African primates.", "content": "Sexual differences in the anterior dentition in African primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207857"} {"pmid": "4207858", "title": "Canine role in dental wear patterns: Macaca nemestrina.", "content": "Canine role in dental wear patterns: Macaca nemestrina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207858"} {"pmid": "4207859", "title": "Thermal solubility of gene 8 coast protein in 2 M urea for fd phage.", "content": "Thermal solubility of gene 8 coast protein in 2 M urea for fd phage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207859"} {"pmid": "4207860", "title": "Chemical modification of tyrosine residue in \"toxin B\" from the venom of the Indian cobra, Naja naja.", "content": "Chemical modification of tyrosine residue in \"toxin B\" from the venom of the Indian cobra, Naja naja.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207860"} {"pmid": "4207861", "title": "Effects of carboxyhemoglobin on the determination of methemoglobin in blood.", "content": "Effects of carboxyhemoglobin on the determination of methemoglobin in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207861"} {"pmid": "4207862", "title": "Prolonged remissions of lymphatic leukemia in DBA-2 mice induced with endogenously produced lactate dehydrogenase antibody.", "content": "Prolonged remissions of lymphatic leukemia in DBA-2 mice induced with endogenously produced lactate dehydrogenase antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207862"} {"pmid": "4207863", "title": "Assay of phospholipids in the amniotic fluid.", "content": "Assay of phospholipids in the amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207863"} {"pmid": "4207864", "title": "Insulin: a comparison of the results of plasma and serum assays using a double-antibody technique.", "content": "Insulin: a comparison of the results of plasma and serum assays using a double-antibody technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207864"} {"pmid": "4207866", "title": "Purification and properties of S-100 protein from porcine brain.", "content": "Purification and properties of S-100 protein from porcine brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207866"} {"pmid": "4207865", "title": "The occurrence and nature of precipitating antibodies in anti-DNA sera.", "content": "The occurrence and nature of precipitating antibodies in anti-DNA sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207865"} {"pmid": "4207867", "title": "L-histidine ammonia-lyase in rat liver. I. Purification and general characteristics.", "content": "L-histidine ammonia-lyase in rat liver. I. Purification and general characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207867"} {"pmid": "4207868", "title": "Sensitivity of Escherichia coli to viral nucleic acid. VII. Further studies on Ca2+-induced competence.", "content": "Sensitivity of Escherichia coli to viral nucleic acid. VII. Further studies on Ca2+-induced competence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207868"} {"pmid": "4207869", "title": "Biosynthesis of seminolipid: sulfation in vivo and in vitro.", "content": "Biosynthesis of seminolipid: sulfation in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207869"} {"pmid": "4207870", "title": "Formation and reversion of Streptomycete protoplasts: cultural condition and morphological study.", "content": "Formation and reversion of Streptomycete protoplasts: cultural condition and morphological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207870"} {"pmid": "4207871", "title": "Mesosomes in Bacillus cereus 569 and the production of extra membranes by treatment with actinomycin-D.", "content": "Mesosomes in Bacillus cereus 569 and the production of extra membranes by treatment with actinomycin-D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207871"} {"pmid": "4207872", "title": "Effects of sodium dodecyl sulphate on the structure of purified pyocin sheaths.", "content": "Effects of sodium dodecyl sulphate on the structure of purified pyocin sheaths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207872"} {"pmid": "4207873", "title": "An investigation by autoradiography and electron microscopy of the localization of prenols in Lactobacillus casei.", "content": "An investigation by autoradiography and electron microscopy of the localization of prenols in Lactobacillus casei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207873"} {"pmid": "4207875", "title": "Failure of buffered 5-hydroxytryptamine to increase brain capillary permeability to albumin in monkeys.", "content": "Failure of buffered 5-hydroxytryptamine to increase brain capillary permeability to albumin in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207875"} {"pmid": "4207874", "title": "Biologic characteristics of transformed rhesus foreskin cells infected with Mason-Pfizer monkey virus.", "content": "Biologic characteristics of transformed rhesus foreskin cells infected with Mason-Pfizer monkey virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207874"} {"pmid": "4207876", "title": "Myiasis of the external auditory meatus.", "content": "Myiasis of the external auditory meatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207876"} {"pmid": "4207877", "title": "The value of alpha-fetoprotein in the prenatal diagnosis of neural tube defects.", "content": "The value of alpha-fetoprotein in the prenatal diagnosis of neural tube defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207877"} {"pmid": "4207878", "title": "Location of double bonds in long chain esters by methoxymercuration-demercuration followed by mass spectroscopy.", "content": "Location of double bonds in long chain esters by methoxymercuration-demercuration followed by mass spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207878"} {"pmid": "4207881", "title": "Pyruvate carboxylase cold inactivation and sulfhydryl groups.", "content": "Pyruvate carboxylase cold inactivation and sulfhydryl groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207881"} {"pmid": "4207886", "title": "Further parasites of the family Garniidae (Coccidiida: Haemosporidiidea) in Brazilian lizards. Fallisia effusa gen.nov., sp.nov. and Fallisia modesta gen.nov., sp.nov.", "content": "Further parasites of the family Garniidae (Coccidiida: Haemosporidiidea) in Brazilian lizards. Fallisia effusa gen.nov., sp.nov. and Fallisia modesta gen.nov., sp.nov.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207886"} {"pmid": "4207887", "title": "Minor physical anomalies and neurologic status in hyperactive boys.", "content": "Minor physical anomalies and neurologic status in hyperactive boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207887"} {"pmid": "4207893", "title": "An unusual lymphoma of the palate.", "content": "An unusual lymphoma of the palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207893"} {"pmid": "4207896", "title": "Metabolism of the hydroxyethylrutosides. II. Excretion and metabolism of 3',4',7-tri-O-(beta-hydroxyethyl) rutoside and related compounds in laboratory animals after parenteral administration.", "content": "Metabolism of the hydroxyethylrutosides. II. Excretion and metabolism of 3',4',7-tri-O-(beta-hydroxyethyl) rutoside and related compounds in laboratory animals after parenteral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207896"} {"pmid": "4207899", "title": "On the nature of the haploid syndrome in Bufo arenarum.", "content": "On the nature of the haploid syndrome in Bufo arenarum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207899"} {"pmid": "4207901", "title": "Maintenance treatment of chronic schizophrenia with neuroleptic drugs.", "content": "Maintenance treatment of chronic schizophrenia with neuroleptic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207901"} {"pmid": "4207902", "title": "Radiation quality independent liquid ionization chamber for dosimetry of electron radiation from medical accelerators.", "content": "Radiation quality independent liquid ionization chamber for dosimetry of electron radiation from medical accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207902"} {"pmid": "4207903", "title": "Gastrointestinal protein loss induced by 60Co irradiation of the abdomen in mice.", "content": "Gastrointestinal protein loss induced by 60Co irradiation of the abdomen in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207903"} {"pmid": "4207904", "title": "Effect of radiation treatment on cell-mediated immune response in carcinoma of the breast.", "content": "Effect of radiation treatment on cell-mediated immune response in carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207904"} {"pmid": "4207905", "title": "Reaction of bromoacetazolamide with crystals of human carbonic anhydrase C.", "content": "Reaction of bromoacetazolamide with crystals of human carbonic anhydrase C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207905"} {"pmid": "4207907", "title": "Fibrin gel structure: influence of calcium and covalent cross-linking on the elasticity.", "content": "Fibrin gel structure: influence of calcium and covalent cross-linking on the elasticity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207907"} {"pmid": "4207906", "title": "Nonidentity of liver alcohol dehydrogenase and the principal protein target of hepatic azocarcinogen.", "content": "Nonidentity of liver alcohol dehydrogenase and the principal protein target of hepatic azocarcinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207906"} {"pmid": "4207908", "title": "Nitrogen isotope effects on the papain-catalyzed hydrolysis of N-benzoyl-L-argininamide.", "content": "Nitrogen isotope effects on the papain-catalyzed hydrolysis of N-benzoyl-L-argininamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207908"} {"pmid": "4207909", "title": "Immunologic and electrophoretic identity between nervous system-specific proteins antigen alpha and 14-3-2.", "content": "Immunologic and electrophoretic identity between nervous system-specific proteins antigen alpha and 14-3-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207909"} {"pmid": "4207910", "title": "Intimal thickening in normocholesterolemic rhesus monkeys fed low supplements of dietary cholesterol.", "content": "Intimal thickening in normocholesterolemic rhesus monkeys fed low supplements of dietary cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207910"} {"pmid": "4207911", "title": "Prostaglandin B2-induced cutaneous vasoconstriction of the canine hind paw.", "content": "Prostaglandin B2-induced cutaneous vasoconstriction of the canine hind paw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207911"} {"pmid": "4207912", "title": "Measurement of IgG and albumin content of cerebrospinal fluid, and its interpretation.", "content": "Measurement of IgG and albumin content of cerebrospinal fluid, and its interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207912"} {"pmid": "4207913", "title": "Ascaridia galli: effects of immunosuppressive drugs or bursectomy in chickens.", "content": "Ascaridia galli: effects of immunosuppressive drugs or bursectomy in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207913"} {"pmid": "4207914", "title": "Theileria annulata: cross-reactions between a cell culture schizont antigen and antigens of East African species in the indirect fluorescent antibody test.", "content": "Theileria annulata: cross-reactions between a cell culture schizont antigen and antigens of East African species in the indirect fluorescent antibody test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207914"} {"pmid": "4207915", "title": "Lack of protection against Trypanosoma cruzi by multiple doses of T. lewisi culture forms. A discussion on some strains of \"lewisi\".", "content": "Lack of protection against Trypanosoma cruzi by multiple doses of T. lewisi culture forms. A discussion on some strains of \"lewisi\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207915"} {"pmid": "4207900", "title": "Mycolonus epilepsy with cherry-red spot in adult: a peculiar form of mucopolysaccharidosis. (A clinical genetic, chemical and ultrastructural study).", "content": "Mycolonus epilepsy with cherry-red spot in adult: a peculiar form of mucopolysaccharidosis. (A clinical genetic, chemical and ultrastructural study).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207900"} {"pmid": "4207916", "title": "Hymenolepis diminuta: an electron microscope study of ion absorption.", "content": "Hymenolepis diminuta: an electron microscope study of ion absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207916"} {"pmid": "4207917", "title": "Protein uptake by the intestine: evidence for absorption of intact macromolecules.", "content": "Protein uptake by the intestine: evidence for absorption of intact macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207917"} {"pmid": "4207919", "title": "A million procrustean beds.", "content": "A million procrustean beds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207919"} {"pmid": "4207918", "title": "Changes in intestinal lactase and alkaline phosphatase activity levels with age in the baboon (Papio papio).", "content": "Changes in intestinal lactase and alkaline phosphatase activity levels with age in the baboon (Papio papio).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207918"} {"pmid": "4207921", "title": "Anaerobic bacteria isolated from decubitus ulcers.", "content": "Anaerobic bacteria isolated from decubitus ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207921"} {"pmid": "4207923", "title": "Radioimmunoassay methods for carcinoembryonic antigen.", "content": "Radioimmunoassay methods for carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207923"} {"pmid": "4207922", "title": "Diagnostic serology inhuman mycoplasmas.", "content": "Diagnostic serology inhuman mycoplasmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207922"} {"pmid": "4207924", "title": "Combination of absorption technique and alpha-amylase activity determination in the same gel medium.", "content": "Combination of absorption technique and alpha-amylase activity determination in the same gel medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207924"} {"pmid": "4207925", "title": "The measurement of IgG anti-IgG antibody in rheumatoid arthritis.", "content": "The measurement of IgG anti-IgG antibody in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207925"} {"pmid": "4207926", "title": "Reversed electroimmunodiffusion for quantitating precipitins.", "content": "Reversed electroimmunodiffusion for quantitating precipitins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207926"} {"pmid": "4207927", "title": "Haemaccel--an improved diluent for incomplete enzyme treated anti-Rh serum.", "content": "Haemaccel--an improved diluent for incomplete enzyme treated anti-Rh serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207927"} {"pmid": "4207928", "title": "The use of cholera toxin for obtaining rabbit secretory immunoglobulins.", "content": "The use of cholera toxin for obtaining rabbit secretory immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207928"} {"pmid": "4207930", "title": "A method for demonstrating mono- and oligomeric units of IgA myeloma proteins in the mouse.", "content": "A method for demonstrating mono- and oligomeric units of IgA myeloma proteins in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207930"} {"pmid": "4207929", "title": "The antigen and virus of Aleutian disease in mink.", "content": "The antigen and virus of Aleutian disease in mink.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207929"} {"pmid": "4207931", "title": "Micro-capillary agglutination.", "content": "Micro-capillary agglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207931"} {"pmid": "4207932", "title": "A two-stage method for cross-linking antibody globulin to ferritin by glutaraldehyde. II. Antigen binding and agglutinating capacity.", "content": "A two-stage method for cross-linking antibody globulin to ferritin by glutaraldehyde. II. Antigen binding and agglutinating capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207932"} {"pmid": "4207933", "title": "Superior colliculus neurons studied during head and eye movements of the behaving monkey.", "content": "Superior colliculus neurons studied during head and eye movements of the behaving monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207933"} {"pmid": "4207934", "title": "Studies on mechanism of inhibition of cardiac muscle contractile tension by ryanodine. Mechanical response.", "content": "Studies on mechanism of inhibition of cardiac muscle contractile tension by ryanodine. Mechanical response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207934"} {"pmid": "4207935", "title": "Evaluation of the effects of the finger fracture technique used in hepatic resection.", "content": "Evaluation of the effects of the finger fracture technique used in hepatic resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207935"} {"pmid": "4207938", "title": "Histochemical study of few enzymes in the adrenaline treated heart of fresh water crab, Paratelphusa masoniana.", "content": "Histochemical study of few enzymes in the adrenaline treated heart of fresh water crab, Paratelphusa masoniana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207938"} {"pmid": "4207939", "title": "Action of exogenous thymidine in vivo on progenitor cell cycle in intestinal epithelium.", "content": "Action of exogenous thymidine in vivo on progenitor cell cycle in intestinal epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207939"} {"pmid": "4207942", "title": "Cytochemical investigations of the metabolism of alveolar and peritoneal macrophages.", "content": "Cytochemical investigations of the metabolism of alveolar and peritoneal macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207942"} {"pmid": "4207944", "title": "Ultrahistochemical demonstration of positively charged groups at the surface of human red blood cells.", "content": "Ultrahistochemical demonstration of positively charged groups at the surface of human red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207944"} {"pmid": "4207947", "title": "I. Distribution of urea-stable and urea-labile lactate dehydrogenase activity in rabbit aorta following a single mechanical dilatation injury: a histochemical study on methodology and histotopography.", "content": "I. Distribution of urea-stable and urea-labile lactate dehydrogenase activity in rabbit aorta following a single mechanical dilatation injury: a histochemical study on methodology and histotopography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207947"} {"pmid": "4207946", "title": "Effect of estradiol on the mouse female reproductive system in organ culture.", "content": "Effect of estradiol on the mouse female reproductive system in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207946"} {"pmid": "4207952", "title": "Comparative recovery of 1972-1973 influenza virus isolates in embryonated eggs and primary rhesus monkey kidney cell cultures after one freeze-thaw cycle.", "content": "Comparative recovery of 1972-1973 influenza virus isolates in embryonated eggs and primary rhesus monkey kidney cell cultures after one freeze-thaw cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207952"} {"pmid": "4207953", "title": "Antimycobacterial activity of some quinolyl aryl sulfides, sulfones, and ethers, in vitro.", "content": "Antimycobacterial activity of some quinolyl aryl sulfides, sulfones, and ethers, in vitro. A series of 61 compounds of six different categories (nitrosulfides, nitrosulfones, aminosulfides, aminosulfones, nitroethers, and aminoethers), all heterocyclic analogues of diaminodiphenyl sulfone (DADS), were synthesized by replacing one of the benzene rings of DADS by a 5-nitro-quinoline ring and the other benzene ring by various heterocyclic nuclei. Among these compounds, 51 were found to inhibit the growth of Mycobacterium tuberculosis at a concentration of 40 mug or less per ml; 8 compounds were effective at a concentration of 1 mug/ml and 9 were effective at a concentration of 0.1 mug/ml. 5-Amino-8-quinolyl-2,4-dichlorophenyl sulfide was found to be 20 times more effective than isonicotinic acid hydrazide and 80 times more effective than streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207953"} {"pmid": "4207954", "title": "Butirosin, a new aminoglycosidic antibiotic complex: bacterial origin and some microbiological studies.", "content": "Butirosin, a new aminoglycosidic antibiotic complex: bacterial origin and some microbiological studies. Butirosin, a new aminoglycosidic antibiotic complex, was produced by submerged fermentation with each of two strains of Bacillus circulans. A paper-disc, agar-diffusion assay which employs Escherichia coli (P-D 04863) as the test organism has been developed. Shaken-flask and stirred-jar fermentations in a medium containing glycerol, soybean meal, meat peptone, ammonium chloride, and calcium carbonate reach titers of 500 to 700 mug of butirosin base per ml. Butirosin is active against several gram-positive and gram-negative bacteria including Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207954"} {"pmid": "4207955", "title": "Concentrations of ampicillin and chloramphenicol in the serum of patients with acute Salmonella enteric fever.", "content": "Concentrations of ampicillin and chloramphenicol in the serum of patients with acute Salmonella enteric fever. Concentrations of ampicillin and chloramphenicol were measured in the serum of patients being treated for acute infections by Salmonella typhi or S. paratyphi A. Ampicillin was administered by the oral or intramuscular routes, whereas chloramphenicol was given orally only. Ampicillin concentrations were highest 1 hr after initiation of intramuscular therapy and 2 hr after oral administration. The serum concentration of ampicillin was significantly higher when it was given intramuscularly than when it was given orally. However, serum concentrations in orally treated patients were approximately the same at 1 hr after the fifth dose as they were 1 hr after the first dose, in contrast to intramuscularly treated patients, in whom the serum concentration of ampicillin was significantly lower 1 hr after the fifth dose. On the other hand, serum concentrations of chloramphenicol were significantly higher after the fifth dose than after the first dose. The rates of cure, relapse, and drug treatment failure were similar for all treatment regimens, and the drug concentrations attained in serum were generally above the minimal inhibitory concentration for the infecting salmonellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207955"} {"pmid": "4207956", "title": "Inhibition of growth of T-strain mycoplasmas by hydroxamic acids and by aurothiomalate.", "content": "Inhibition of growth of T-strain mycoplasmas by hydroxamic acids and by aurothiomalate. Sorbyl-, benzoyl-, and 3-amino-benzoyl hydroxamic acids inhibited the development of an alkaline pH by T-strain cultures grown in broth containing 0.05% urea and phenol red. The specificity of this urease inhibition was demonstrated by the inhibition, by 10(-4)m sorbyl-hydroxamic acid, of the release of (14)CO(2) from (14)C-urea by washed T-strain mycoplasmas in 4 hr of incubation. Sorbyl-, benzoyl-, and 3-amino-benzoyl hydroxamic acids at a concentration of 10(-3)m markedly inhibited the multiplication of T-strain 354 during 18 hr of incubation; this inhibition was not corrected by thymidine at a concentration of 500 mug per ml. Aurothiomalate was 20 times more inhibitory to Mycoplasma hominis DC-63 than to T-strain 354; equivalent inhibitory concentrations were 50 mug per ml for M. hominis and 1,200 mug per ml for T strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207956"} {"pmid": "4207958", "title": "Uptake and binding of 14C-ethambutol by tubercle bacilli and the relation of binding to growth inhibition.", "content": "Uptake and binding of 14C-ethambutol by tubercle bacilli and the relation of binding to growth inhibition. Studies were designed to characterize ethambutol uptake by Mycobacterium tuberculosis (H37Ra) and to relate uptake to the time-dependent, concentration-independent nature of growth inhibition by ethambutol. When cells grown aerated at 37 C in Sauton medium were exposed for 7 hr to 0.2, 0.5, 1.0, 2.5, and 5.0 mug of (14)C-ethambutol per ml, uptake increased with time and was a linear function of concentration. The process was inhibited at 22 C. Studies with chloramphenicol, sodium azide, and 2,4-dinitrophenol indicated that uptake is independent of requirements for protein synthesis and energy. The organism did not accumulate ethambutol against a concentration gradient. It can be concluded that ethambutol enters the cells in a passive manner. Kinetic studies of (14)C loss from tubercle bacilli pretreated with labeled drug suggested the existence of two ethambutol fractions within the cell: a highly variable labile pool and a second fraction that is small and quite firmly bound. Levels of cell-bound drug may be independent of total uptake, but this possibility was not established unequivocally. Definitive evidence showing identity in the concentrations of bound drug regardless of total uptake could explain the apparent discrepancy between concentration-dependent uptake and concentration-independent growth inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207958"} {"pmid": "4207957", "title": "Simple photometric assay of beta-lactamase activity.", "content": "Simple photometric assay of beta-lactamase activity. A simple photometric assay of beta-lactamase activity was developed. The method is based on a decrease in optical density at 620 nm caused by the formation of a penicilloic acid-iodine complex. The enzymatic reaction is instantaneously stopped by the addition of a concentrated iodine-tungstate solution. Data showing the time and concentration dependence of the reaction are presented. By varying both the time of the assay and the concentration of the enzyme, substrates of widely different V(max) values could be assayed. The assay is compared with other methods of determining beta-lactamase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207957"} {"pmid": "4207959", "title": "The role of lysosomes in production of ischemic nerve cell changes.", "content": "The role of lysosomes in production of ischemic nerve cell changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207959"} {"pmid": "4207960", "title": "Cue-locus--a factor in the behavioral deficiency of the developing protein-malnourished monkey (Macaca Mulatta).", "content": "Cue-locus--a factor in the behavioral deficiency of the developing protein-malnourished monkey (Macaca Mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207960"} {"pmid": "4207961", "title": "Editorial: Methoxyflurane nephrotoxicity.", "content": "Editorial: Methoxyflurane nephrotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207961"} {"pmid": "4207962", "title": "Editorial: Gonorrhoea of the pharynx.", "content": "Editorial: Gonorrhoea of the pharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207962"} {"pmid": "4207963", "title": "Diagnosis and treatment of essential fatty acid deficiency in man.", "content": "Diagnosis and treatment of essential fatty acid deficiency in man. Essential fatty acid deficiency was found on four occasions in three adult patients with malabsorption after intestinal resection. Diagnosis was primarily based on the gas chromatographic finding of the abnormal fatty acid 5, 8, 11- (omega9) eicosatrienoic acid in plasma lecithin. None of the patients had received parenteral nutrition with a fat-free source of calories but all had been on a reduced intake of dietary fat at some stage. Treatment with intravenous Intralipid rapidly reversed the abnormal plasma fatty acid pattern and also cleared the rash in the patient wih he most severe deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207963"} {"pmid": "4207964", "title": "Prevalence of hepatitis B antigen and antibody in prostitutes.", "content": "Prevalence of hepatitis B antigen and antibody in prostitutes. We investigated the prevalence of hepatitis B antigen (HBAg) and antibody (HBAb) in 293 prostitutes and in 379 pregnant women of similar age and of low socioeconomic level, who served as controls. HBAg was found in 4.4% of prostitutes and 3.4% of controls. The prevalence of HBAb was significantly higher (P <0.001) in prostitutes (56.7%) than in controls (24.5%). The prevalence of HBAb was clearly age-dependent in both groups. Evidence of hepatitis B virus infection significantly increased with the number of years in prostitution. The evidence of increased infection rates among prostitutes and their distribution support the hypothesis that hepatitis B infection is sexually transmitted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207964"} {"pmid": "4207965", "title": "\"Anticonvulsant action\" of vitamin D in epileptic patients? A controlled pilot study.", "content": "\"Anticonvulsant action\" of vitamin D in epileptic patients? A controlled pilot study. The frequency of epileptic seizures was observed in a controlled therapeutic trial on 23 epileptic inpatients before and after treatment with vitamin D(2) or placebo in addition to anticonvulsant drugs. The number of seizures was reduced during treatment with vitamin D(2) but not with placebo. The effect was unrelated to changes in serum calcium or magnesium. The results may support the concept that epileptics should be treated prophylactically with vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207965"} {"pmid": "4207966", "title": "Immunochemical method for quantitative estimation of an inducible enzyme--lupanine hydroxylase.", "content": "Immunochemical method for quantitative estimation of an inducible enzyme--lupanine hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207966"} {"pmid": "4207968", "title": "Complications of intravenous alimentation in seriously ill infants.", "content": "Complications of intravenous alimentation in seriously ill infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207968"} {"pmid": "4207967", "title": "Chemically defined diets.", "content": "Chemically defined diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207967"} {"pmid": "4207969", "title": "The Fürbringer hypothesis of nerve-muscle specificity reexamined with respect to the facial musculature.", "content": "The Fürbringer hypothesis of nerve-muscle specificity reexamined with respect to the facial musculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207969"} {"pmid": "4207970", "title": "Clinical experiences with the use of cromolyn sodium in asthmatic children.", "content": "Clinical experiences with the use of cromolyn sodium in asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207970"} {"pmid": "4207972", "title": "Asthma. Panel discussion. Question and answer session.", "content": "Asthma. Panel discussion. Question and answer session.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207972"} {"pmid": "4207971", "title": "Selection of patients for cromolyn therapy.", "content": "Selection of patients for cromolyn therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207971"} {"pmid": "4207973", "title": "Asthma control: an update.", "content": "Asthma control: an update.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207973"} {"pmid": "4207975", "title": "Analysis of tRNAs during the development of Drosophila.", "content": "Analysis of tRNAs during the development of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207975"} {"pmid": "4207976", "title": "Expression of xanthine dehydrogenase activity during embryonic development of Drosophila melanogaster.", "content": "Expression of xanthine dehydrogenase activity during embryonic development of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207976"} {"pmid": "4207977", "title": "The maternal and zygotic control of development by cinnamon, a new mutant in Drosophila melanogaster.", "content": "The maternal and zygotic control of development by cinnamon, a new mutant in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207977"} {"pmid": "4207979", "title": "Variations in myoneme birefringence in relation to length changes in Stentor coeruleus.", "content": "Variations in myoneme birefringence in relation to length changes in Stentor coeruleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207979"} {"pmid": "4207980", "title": "The shuttling activity of nuclear RNAs is not an artefact of experimental manipulation.", "content": "The shuttling activity of nuclear RNAs is not an artefact of experimental manipulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207980"} {"pmid": "4207978", "title": "The synthetic and minimal culture requirements for evagination of imaginal discs of Drosophila melanogaster in vitro.", "content": "The synthetic and minimal culture requirements for evagination of imaginal discs of Drosophila melanogaster in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207978"} {"pmid": "4207981", "title": "The oral apparatus of Tetrahymena pyriformis, mating type 1, variety 1. I. Solubilization and electrophoretic separation of oral apparatus proteins.", "content": "The oral apparatus of Tetrahymena pyriformis, mating type 1, variety 1. I. Solubilization and electrophoretic separation of oral apparatus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207981"} {"pmid": "4207983", "title": "Personnel practices in long-term care facilities.", "content": "Personnel practices in long-term care facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207983"} {"pmid": "4207984", "title": "Polycarboxylate cement as a pulp capping agent.", "content": "Polycarboxylate cement as a pulp capping agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207984"} {"pmid": "4207990", "title": "Carbamazepine for epilepsy. A controlled prospective evaluation.", "content": "Carbamazepine for epilepsy. A controlled prospective evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207990"} {"pmid": "4207991", "title": "Radionuclide scanning and microangiography of evolving and completed brain infarction. A correlative study in monkeys.", "content": "Radionuclide scanning and microangiography of evolving and completed brain infarction. A correlative study in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207991"} {"pmid": "4207992", "title": "Simultaneous measurement of internal and external carotid blood flow in the monkey. An approach to the study of migraine mechanisms.", "content": "Simultaneous measurement of internal and external carotid blood flow in the monkey. An approach to the study of migraine mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207992"} {"pmid": "4207995", "title": "Effect of synthetic salmon calcitonin on iodine metabolism in rabbits.", "content": "Effect of synthetic salmon calcitonin on iodine metabolism in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207995"} {"pmid": "4207994", "title": "Role of histaminase and corticosterone on the depletion of tissue histamine in the irradiated rats.", "content": "Role of histaminase and corticosterone on the depletion of tissue histamine in the irradiated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207994"} {"pmid": "4207998", "title": "The immunosuppressive potency of antilymphocyte serum is related to activity against human thymic lymphocyte-specific antigens.", "content": "The immunosuppressive potency of antilymphocyte serum is related to activity against human thymic lymphocyte-specific antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4207998"} {"pmid": "4208009", "title": "Prophylactic antibiotics in elective abdominal hysterectomy.", "content": "Prophylactic antibiotics in elective abdominal hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208009"} {"pmid": "4208010", "title": "An integrated direct functional test of the adenohypophysis.", "content": "An integrated direct functional test of the adenohypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208010"} {"pmid": "4208011", "title": "The effect of force on craniofacial development.", "content": "The effect of force on craniofacial development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208011"} {"pmid": "4208012", "title": "Separation of sulfur-containing components of transfer ribonucleic acid on Bio-Gel P-2 and Sephadex G-10 columns.", "content": "Separation of sulfur-containing components of transfer ribonucleic acid on Bio-Gel P-2 and Sephadex G-10 columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208012"} {"pmid": "4208013", "title": "Automated determination of delta-aminolevulinic acid dehydratase activity in human erythrocytes.", "content": "Automated determination of delta-aminolevulinic acid dehydratase activity in human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208013"} {"pmid": "4208014", "title": "Semi-automated ninhydrin assay of Kjeldahl nitrogen.", "content": "Semi-automated ninhydrin assay of Kjeldahl nitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208014"} {"pmid": "4208015", "title": "Intraocular injection of gentamicin. Single injection therapy of experimental bacterial endophthalmitis.", "content": "Intraocular injection of gentamicin. Single injection therapy of experimental bacterial endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208015"} {"pmid": "4208016", "title": "Acid hydrolase deficiencies and abnormal glycoproteins in mucolipidosis. 3 (pseudo-Hurler polydystrophy).", "content": "Acid hydrolase deficiencies and abnormal glycoproteins in mucolipidosis. 3 (pseudo-Hurler polydystrophy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208016"} {"pmid": "4208017", "title": "Proceedings: Population differences in meiotic recombination frequency between loci on chromosome 1.", "content": "Proceedings: Population differences in meiotic recombination frequency between loci on chromosome 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208017"} {"pmid": "4208018", "title": "Proceedings: A family study suggesting genetic linkage of phosphopyruvate hydratse (enolase) to the Rh blood group system.", "content": "Proceedings: A family study suggesting genetic linkage of phosphopyruvate hydratse (enolase) to the Rh blood group system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208018"} {"pmid": "4208019", "title": "Further evidence for cortical control over replication of the macronucleus and basal bodies in Stentor.", "content": "Further evidence for cortical control over replication of the macronucleus and basal bodies in Stentor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208019"} {"pmid": "4208020", "title": "Transplantation of nuclei into the polar plasm of Drosophila eggs.", "content": "Transplantation of nuclei into the polar plasm of Drosophila eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208020"} {"pmid": "4208021", "title": "Effect of cytochalasin B on the evagination in vitro of leg imaginal discs.", "content": "Effect of cytochalasin B on the evagination in vitro of leg imaginal discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208021"} {"pmid": "4208022", "title": "Pigment cell development in rhesus monkey eyes: an electron microscopic and histochemical study.", "content": "Pigment cell development in rhesus monkey eyes: an electron microscopic and histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208022"} {"pmid": "4208023", "title": "Development of glycogen storage ability under cortisol control in primary cultures of rat fetal hepatocytes.", "content": "Development of glycogen storage ability under cortisol control in primary cultures of rat fetal hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208023"} {"pmid": "4208024", "title": "Temperature-sensitive mutations in Drosophila melanogaster. 8. Temperature-sensitive periods of the lethal and morphological phenotypes of selected combinations of notch-locus mutations.", "content": "Temperature-sensitive mutations in Drosophila melanogaster. 8. Temperature-sensitive periods of the lethal and morphological phenotypes of selected combinations of notch-locus mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208024"} {"pmid": "4208025", "title": "Pattern formation in imaginal discs of Drosophila melanogaster after irradiation of embryos and young larvae.", "content": "Pattern formation in imaginal discs of Drosophila melanogaster after irradiation of embryos and young larvae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208025"} {"pmid": "4208026", "title": "The development of the imaginal abdomen of Drosophila melanogaster.", "content": "The development of the imaginal abdomen of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208026"} {"pmid": "4208027", "title": "Developmental properties of Shibire: a pleiotropic mutation affecting larval and adult locomotion and development.", "content": "Developmental properties of Shibire: a pleiotropic mutation affecting larval and adult locomotion and development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208027"} {"pmid": "4208028", "title": "Partricin, an antifungal and antiprotozoal polyene antibiotic.", "content": "Partricin, an antifungal and antiprotozoal polyene antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208028"} {"pmid": "4208029", "title": "Editorial: Coxsackie heart disease.", "content": "Editorial: Coxsackie heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208029"} {"pmid": "4208030", "title": "Comparative study of Minocycline and Ampicillin in the treatment of urinary tract infections.", "content": "Comparative study of Minocycline and Ampicillin in the treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208030"} {"pmid": "4208031", "title": "Bioavailability of primidone in epileptic patients.", "content": "Bioavailability of primidone in epileptic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208031"} {"pmid": "4208032", "title": "Effect of long-term administration of Pindolol (LB-46, Visken) in essential circulatory hyperkinesis. A double-blind, cross-over study.", "content": "Effect of long-term administration of Pindolol (LB-46, Visken) in essential circulatory hyperkinesis. A double-blind, cross-over study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208032"} {"pmid": "4208034", "title": "The use of tissue adhesive (isobutyl cyanoacrylate) and topical steroid (0.1 percent dexamethasone) in experimental tympanoplasty.", "content": "The use of tissue adhesive (isobutyl cyanoacrylate) and topical steroid (0.1 percent dexamethasone) in experimental tympanoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208034"} {"pmid": "4208033", "title": "Studies on the surface of chick blastoderm cells. 3. Calcium binding to ionogenic sites.", "content": "Studies on the surface of chick blastoderm cells. 3. Calcium binding to ionogenic sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208033"} {"pmid": "4208035", "title": "Effects of lead on the vestibular system: preliminary findings.", "content": "Effects of lead on the vestibular system: preliminary findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208035"} {"pmid": "4208036", "title": "Letter: When is glutamate neurotoxic?", "content": "Letter: When is glutamate neurotoxic?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208036"} {"pmid": "4208037", "title": "Policy options and the impact of national health insurance.", "content": "Policy options and the impact of national health insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208037"} {"pmid": "4208038", "title": "Diabetic ketoacidosis.", "content": "Diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208038"} {"pmid": "4208041", "title": "The effect of experimental spasm on the CO2 response of cerebral bloodflow in primates.", "content": "The effect of experimental spasm on the CO2 response of cerebral bloodflow in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208041"} {"pmid": "4208042", "title": "Autolysis in Listeria monocytogenes: effect of inhibitors of cell wall and protein synthesis.", "content": "Autolysis in Listeria monocytogenes: effect of inhibitors of cell wall and protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208042"} {"pmid": "4208044", "title": "Lipid and bone matrix calcification in vitro.", "content": "Lipid and bone matrix calcification in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208044"} {"pmid": "4208043", "title": "Hypertonic salt extraction of HL-A antigens: assessment of protease activity.", "content": "Hypertonic salt extraction of HL-A antigens: assessment of protease activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208043"} {"pmid": "4208045", "title": "Growth inhibition and pyocin receptor properties of endotoxin from Pseudomonas aeruginosa.", "content": "Growth inhibition and pyocin receptor properties of endotoxin from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208045"} {"pmid": "4208046", "title": "Factors affecting autolysis of Neisseria gonorrhoeae.", "content": "Factors affecting autolysis of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208046"} {"pmid": "4208047", "title": "Sensitization of E. coli to the serum bactericidal system and to lysozyme by ethyleneglycoltetraacetic acid.", "content": "Sensitization of E. coli to the serum bactericidal system and to lysozyme by ethyleneglycoltetraacetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208047"} {"pmid": "4208048", "title": "Chemistry of hypothalamic releasing factors.", "content": "Chemistry of hypothalamic releasing factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208048"} {"pmid": "4208049", "title": "Further observations on the structure and function of median eminence, with reference to the organization of RF-producing elements in the endocrine hypothalamus.", "content": "Further observations on the structure and function of median eminence, with reference to the organization of RF-producing elements in the endocrine hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208049"} {"pmid": "4208050", "title": "The influence of the circadian thyrotropin rhythm on the thyrotropin response to thyrotropin-releasing hormone in normal subjects.", "content": "The influence of the circadian thyrotropin rhythm on the thyrotropin response to thyrotropin-releasing hormone in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208050"} {"pmid": "4208051", "title": "Investigation of Bacillus subtilis mutants with changed capacity for formation of competent cells.", "content": "Investigation of Bacillus subtilis mutants with changed capacity for formation of competent cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208051"} {"pmid": "4208052", "title": "Influence of vasopressin and topical bile salts on the gastric mucosal barrier of the subhuman primate.", "content": "Influence of vasopressin and topical bile salts on the gastric mucosal barrier of the subhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208052"} {"pmid": "4208053", "title": "Total body potassium in surgical patients.", "content": "Total body potassium in surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208053"} {"pmid": "4208055", "title": "Affective state and thyrotropin and prolactin responses after repeated injections of thyrotropin-releasing hormone in depressed patients.", "content": "Affective state and thyrotropin and prolactin responses after repeated injections of thyrotropin-releasing hormone in depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208055"} {"pmid": "4208058", "title": "The relationships between nitrogen fixation and photosynthesis. The third Rubbo Memorial Oration, 1972.", "content": "The relationships between nitrogen fixation and photosynthesis. The third Rubbo Memorial Oration, 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208058"} {"pmid": "4208059", "title": "Concentrations of immunoglobulins and albumin in lymph collected from various regions of the body of the sheep.", "content": "Concentrations of immunoglobulins and albumin in lymph collected from various regions of the body of the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208059"} {"pmid": "4208060", "title": "D-alanine carboxypeptidase from Streptococcus faecalis.", "content": "D-alanine carboxypeptidase from Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208060"} {"pmid": "4208061", "title": "Estimations of membrane potentials in Streptococcus faecalis by means of a fluorescent probe.", "content": "Estimations of membrane potentials in Streptococcus faecalis by means of a fluorescent probe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208061"} {"pmid": "4208062", "title": "Adsorption of bacteriophages specific for Pseudomonas aeruginosa R factors RP1 and R1822.", "content": "Adsorption of bacteriophages specific for Pseudomonas aeruginosa R factors RP1 and R1822.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208062"} {"pmid": "4208063", "title": "Discrimination of isolation peep variants by squirrel monkeys.", "content": "Discrimination of isolation peep variants by squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208063"} {"pmid": "4208065", "title": "Incidence of minor fractures in twisting injuries of the ankle.", "content": "Incidence of minor fractures in twisting injuries of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208065"} {"pmid": "4208066", "title": "Medial dislocation of the ankle without fracture: a case report.", "content": "Medial dislocation of the ankle without fracture: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208066"} {"pmid": "4208067", "title": "Comparison of ophthalmic vehicles using fluorescein uptake technique.", "content": "Comparison of ophthalmic vehicles using fluorescein uptake technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208067"} {"pmid": "4208068", "title": "Cross reactions to antigens causing hypersensitivity pneumonitis.", "content": "Cross reactions to antigens causing hypersensitivity pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208068"} {"pmid": "4208069", "title": "Erythema marginatum preceding hereditary angioedema.", "content": "Erythema marginatum preceding hereditary angioedema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208069"} {"pmid": "4208070", "title": "Factors influencing the frequency of mesosomes observed in fixed and unfixed cells of Streptococcus faecalis.", "content": "Factors influencing the frequency of mesosomes observed in fixed and unfixed cells of Streptococcus faecalis. Mesosomes of Streptococcus faecalis (American Type Culture Collection 9790) were seen about 92% less frequently in freeze fractures of unfixed cells than in freeze fractures and sections of fixed cells. This difference in frequency was not related to any period of unbalanced macromolecular synthesis induced by chemical fixation. All measured synthetic processes (DNA, RNA, and protein synthesis, and glycerol incorporation) were halted with either osmium tetroxide (OS) or glutaraldehyde fixation. That fewer mesosomes were seen in freeze fractures of unfixed cells was probably due to the difficulty of observing cross-fractured mesosomes in this organism in the unfixed state. Unfortunately, mesosomes probably preferentially cross fracture in the unfixed state and therefore are usually only observed, infrequently, in those cases where the freeze fracture follows the surface layer of a mesosomal membrane. However, the addition of glycerol to unfixed cells, especially in the chilled state, greatly increased the frequency of observation of cytoplasmic mesosomes in freeze fractures. It is thought that glycerol, like chemical fixation, increases the number of surface-fractured mesosomes, which in turn increases the frequency of mesosome observation. It was also observed that cellular autolysis occurring during OS fixation seemingly reduced the number of mesosomes observed in thin sections and freeze fractures of OS-fixed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208070"} {"pmid": "4208071", "title": "Nafenopin-induced hepatic microbody (peroxisome) proliferation and catalase synthesis in rats and mice. Absence of sex difference in response.", "content": "Nafenopin-induced hepatic microbody (peroxisome) proliferation and catalase synthesis in rats and mice. Absence of sex difference in response. Nafenopin (2-methyl-2[p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy]-propionic acid; Su-13437), a potent hypolipidemic compound, was administered in varying concentrations in ground Purina Chow to male and female rats, wild type (Cs(a) strain) mice and acatalasemic (Cs(b) strain) mice to determine the hepatic microbody proliferative and catalase-inducing effects. In all groups of animals, administration of nafenopin at dietary levels of 0.125% and 0.25% produced a significant and sustained increase in the number of peroxisomes. The hepatic microbody proliferation in both male and female rats and wild type Cs(a) strain mice treated with nafenopin was of the same magnitude and was associated with a two-fold increase in catalase activity and in the concentration of catalase protein. The increase in microbody population in acatalasemic mice, although not accompanied by increase in catalase activity, was associated with a twofold increase in the amount of catalase protein. The absence of sex difference in microbody proliferative response in nafenopin-treated rats and wild type mice is of particular significance, since ethyl-alpha-p-chlorophenoxyisobutyrate (CPIB)-induced microbody proliferation and increase in catalase activity occurred only in males. Nafenopin can, therefore, be used as an inducer of microbody proliferation and of catalase synthesis in both sexes of rats and mice. The serum glycerol-glycerides were markedly lowered in all the animals given nafenopin, which paralleled the increase in liver catalase. All the above effects of nafenopin were fully reversed when the drug was withdrawn from the diet of male rats. During reversal, several microbody nucleoids were seen free in the hyaloplasm or in the dilated endoplasmic reticulum channels resulting from a rapid reduction in microbody matrix proteins after the withdrawal of nafenopin from the diet. Because of microbody proliferation and catalase induction with increasing number of hypolipidemic compounds, additional studies are necessary to determine the interrelationships of microbody proliferation, catalase induction, and hypolipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208071"} {"pmid": "4208072", "title": "Accumulation of replicative intermediates of mitochondrial DNA in Tetrahymena pyriformis grown in ethidium bromide.", "content": "Accumulation of replicative intermediates of mitochondrial DNA in Tetrahymena pyriformis grown in ethidium bromide. The effect of growth of Tetrahymena pyriformis in ethidium bromide (EthBr) on the structure and synthesis of mitochondrial DNA (mtDNA) has been investigated. During the first 5 h of growth in EthBr, mtDNA synthesis is inhibited 95% or more. After 10-15 h, this block is partially released and large numbers of replicating molecules accumulate, indicating that inhibition by EthBr primarily affects the rate of chain growth and not the initiation of new rounds of replication. The accumulated molecules sediment more rapidly than normal Tetrahymena mtDNA and do not contain enough single-strand regions to distinguish them from normal Tetrahymena mtDNA when banded in buoyant CsCl or NaI gradients. Electron microscopy shows that the predominant species in this rapidly sedimenting DNA is a linear molecule containing one symmetrical double-stranded replication loop of varying size located at its center. No degradation of mtDNA from cells grown in EthBr was detected in alkaline velocity gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208072"} {"pmid": "4208073", "title": "Autoradiographic localization of 13N after fixation of 13N-labeled nitrogen gas by a heterocyst-forming blue-green alga.", "content": "Autoradiographic localization of 13N after fixation of 13N-labeled nitrogen gas by a heterocyst-forming blue-green alga. (13)N, generated by proton bombardment of (13)C powder, is rapidly and easily converted to (13)N-N(2), 0.01 atm pressure, ca. 10 mCi/ml, by automated Dumas combustion. (13)N fixed (as (13)N-N(2)) by algal filaments was localized by an autoradiographic technique which permits track autoradiography with isotopes having short half-lives. Our findings show directly that a minimum of about 25% of the N(2) fixation by intact, aerobically grown filaments of Anabaena cylindrica is carried out by the heterocysts. If all of the N(2) fixation takes place in the heterocysts, then the movement of nitrogen along the filaments can be characterized by a constant tau < ca. 5 s (cell(-2)).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208073"} {"pmid": "4208075", "title": "Vasopressin-induced changes in the toad urinary bladder epithelial surface.", "content": "Vasopressin-induced changes in the toad urinary bladder epithelial surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208075"} {"pmid": "4208074", "title": "Action of cytochalasin D on cells of established lines. I. Early events.", "content": "Action of cytochalasin D on cells of established lines. I. Early events. HeLa, Vero, L, HEp2, and MDBK cells respond immediately to 0.2-0.5 microg/ml cytochalasin D (CD) with sustained contraction (contracture), loss of microvilli, expression of endoplasmic contents (zeiosis), nuclear protrusion, and extension of cytoplasmic processes. The development of these changes is depicted, and the dose-response patterns in these cell lines are described. MDBK is generally most resistant and HeLa most sensitive to these effects of CD. Cells in G(1) are most sensitive to CD; responsiveness decreases progressively during early S and is least in mid S through G(2). CD inhibits transport of [(14)C]deoxyglucose in HeLa by about 45% but has no significant effect on hexose uptake in Vero and MDBK; sugar transport is thus apparently unrelated to any morphologic effect of CD. Although spreading and attachment are impeded, CD does not decrease and may even enhance the adhesiveness of established monolayers. Contraction appears to be a primary early effect of CD, upon which other visible changes follow. It is prevented by some inhibitors of energy metabolism (deoxyglucose and dinitrophenol) and does not occur in glycerinated models without ATP. The possible bases of the contractile response to CD are discussed. Although direct or indirect action of CD on some microfilaments may occur, a generalized structural disruption of contractile filaments by CD is considered unlikely.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208074"} {"pmid": "4208079", "title": "Inhibition by carboxylic acids of an o-diphenol oxidase from Prunus avium fruits.", "content": "Inhibition by carboxylic acids of an o-diphenol oxidase from Prunus avium fruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208079"} {"pmid": "4208080", "title": "The efficacy of systemic antibiotics in the treatment of granulating wounds.", "content": "The efficacy of systemic antibiotics in the treatment of granulating wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208080"} {"pmid": "4208081", "title": "Cardiopulmonary changes with veno-arterial bypass in the hypoxic primate.", "content": "Cardiopulmonary changes with veno-arterial bypass in the hypoxic primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208081"} {"pmid": "4208082", "title": "Mitral valve replacement with the glutaraldehyde-preserved porcine heterograft. Clinical, hemodynamic, and pathological correlations.", "content": "Mitral valve replacement with the glutaraldehyde-preserved porcine heterograft. Clinical, hemodynamic, and pathological correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208082"} {"pmid": "4208084", "title": "Cancer of the gastrointestinal Tract. D. Gastric cancer: treatment principles.", "content": "Cancer of the gastrointestinal Tract. D. Gastric cancer: treatment principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208084"} {"pmid": "4208083", "title": "A new diagnostic test for acute myocardial infarction. The detection of myoglobinuria by radioimmunodiffusion assay.", "content": "A new diagnostic test for acute myocardial infarction. The detection of myoglobinuria by radioimmunodiffusion assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208083"} {"pmid": "4208089", "title": "Studies on precipitating antibodies for Aspergillus flavus antigens in patients with proliferative diseases.", "content": "Studies on precipitating antibodies for Aspergillus flavus antigens in patients with proliferative diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208089"} {"pmid": "4208099", "title": "Comparative distemper vaccine titrations in ferrets and minks.", "content": "Comparative distemper vaccine titrations in ferrets and minks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208099"} {"pmid": "4208101", "title": "Drugs which inhibit prostaglandin biosynthesis.", "content": "Drugs which inhibit prostaglandin biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208101"} {"pmid": "4208102", "title": "Antibiotic-disinfection compatibility studies in solution used for dipping turkey hatching eggs.", "content": "Antibiotic-disinfection compatibility studies in solution used for dipping turkey hatching eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208102"} {"pmid": "4208104", "title": "The effect of environmental temperature on parathyphoid infection in the neonatal chicken.", "content": "The effect of environmental temperature on parathyphoid infection in the neonatal chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208104"} {"pmid": "4208103", "title": "Some effects of DDT, toxaphene and polychlorinated biphenyl on thyroid function in Bobwhite quail.", "content": "Some effects of DDT, toxaphene and polychlorinated biphenyl on thyroid function in Bobwhite quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208103"} {"pmid": "4208110", "title": "Some causal factors in autogrooming behaviour of adult Stump-Tailed Macaques (Macaca arctoides).", "content": "Some causal factors in autogrooming behaviour of adult Stump-Tailed Macaques (Macaca arctoides).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208110"} {"pmid": "4208111", "title": "The development of sociosexual behaviours in Japanese macaques Macaca fuscata.", "content": "The development of sociosexual behaviours in Japanese macaques Macaca fuscata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208111"} {"pmid": "4208112", "title": "Triadic differentiation: an inhibitory process protecting pair bonds in baboons.", "content": "Triadic differentiation: an inhibitory process protecting pair bonds in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208112"} {"pmid": "4208113", "title": "Mercapturic acid biosynthesis: the separate identities of glutathione-S-aryl chloride transferase and ligandin.", "content": "Mercapturic acid biosynthesis: the separate identities of glutathione-S-aryl chloride transferase and ligandin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208113"} {"pmid": "4208114", "title": "The combined effect of glycogen and ATP on the D to I conversion of glycogen synthetase.", "content": "The combined effect of glycogen and ATP on the D to I conversion of glycogen synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208114"} {"pmid": "4208115", "title": "Generation of parvalbumin-like proteins from troponin.", "content": "Generation of parvalbumin-like proteins from troponin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208115"} {"pmid": "4208116", "title": "The effect of ionic strength on alkaline phosphatase.", "content": "The effect of ionic strength on alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208116"} {"pmid": "4208117", "title": "Carbonic anhydrase isoenzyme B in the erythrocytes of uremic subjects.", "content": "Carbonic anhydrase isoenzyme B in the erythrocytes of uremic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208117"} {"pmid": "4208118", "title": "Triiodothyronine radioimmunoassay: a study of the interactions of T3 with anti-T3 antisera and with thyroxine binding globulin in the presence of ANS (ammonium-8-anilino naphthalene-1-sulfonate).", "content": "Triiodothyronine radioimmunoassay: a study of the interactions of T3 with anti-T3 antisera and with thyroxine binding globulin in the presence of ANS (ammonium-8-anilino naphthalene-1-sulfonate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208118"} {"pmid": "4208119", "title": "A study on the kinetics of pancreatic kallikrein with the substrate benzoyl arginine ethyl ester using a spectrophotometric assay.", "content": "A study on the kinetics of pancreatic kallikrein with the substrate benzoyl arginine ethyl ester using a spectrophotometric assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208119"} {"pmid": "4208120", "title": "3-Methoxy-4-hydroxyphenethylene glycol in plasma.", "content": "3-Methoxy-4-hydroxyphenethylene glycol in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208120"} {"pmid": "4208121", "title": "Immunoglobulin A (IgA) with properties of both cryoglobulin and pyroglobulin.", "content": "Immunoglobulin A (IgA) with properties of both cryoglobulin and pyroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208121"} {"pmid": "4208122", "title": "Separation of folates from antibiotics using triethylamino cellulose.", "content": "Separation of folates from antibiotics using triethylamino cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208122"} {"pmid": "4208127", "title": "Immunoreactive growth hormone levels in mice with the obese-hyperglycemic syndrome (genotype obob).", "content": "Immunoreactive growth hormone levels in mice with the obese-hyperglycemic syndrome (genotype obob).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208127"} {"pmid": "4208128", "title": "Thyrotrophin response to intravenous thyrotrophin-releasing hormone in patients with hepatic and renal disease.", "content": "Thyrotrophin response to intravenous thyrotrophin-releasing hormone in patients with hepatic and renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208128"} {"pmid": "4208129", "title": "Localization of proteinase(s) near the cell surface of Streptococcus lactis.", "content": "Localization of proteinase(s) near the cell surface of Streptococcus lactis. Two criteria suggest that most of the proteinase of Streptococcus lactis is localized in the cell wall. (i) Intact cells possess proteinase activity when incubated with a high-molecular-weight substrate. (ii) Most of the cell-bound proteinase activity is released during spheroplast formation under conditions which result in the release of only 1% of the intracellular enzymes aldolase and glyceraldehyde-3-phosphate dehydrogenase. The solubilized cell wall, plasma membrane, and cytoplasm fractions contained 84, 0, and 16%, respectively, of the total proteinase activity with casein as substrate. The physiological role of a surface-bound proteinase in this organism is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208129"} {"pmid": "4208130", "title": "Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: ultrastructure of competent and noncompetent cells and cellular changes during development of competence.", "content": "Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: ultrastructure of competent and noncompetent cells and cellular changes during development of competence. By means of electron microscope autoradiography of component cultures of Bacillus subtilis exposed to [(3)H]thymidine-labeled transforming deoxyribonucleic acid competent and noncompetent cells can be distinguished. Competence is not limited to a specific phase of the cell division cycle. With serial section electron microscopy of competent and noncompetent cells, two types of mesosomal structures are observed: mesosomes connected to the plasma membrane only (plasma membrane mesosomes) and mesosomes which are additionally connected to the nuclear bodies (nuclear mesosomes). The two types show different cellular distributions. Especially the number of nuclear mesosomes is higher in competent than in noncompetent cells. This, and the observation that the increase and decrease of competence is correlated with both the number of cells carrying nuclear mesosomes and the number of nuclear mesosomes per cell, suggests that mesosomes are involved in the acquisition of competence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208130"} {"pmid": "4208132", "title": "Novel ribonucleic acid species accumulated in the dark in the blue-green alga Anacystis nidulans.", "content": "Novel ribonucleic acid species accumulated in the dark in the blue-green alga Anacystis nidulans. In the dark, the obligately photoautotrophic blue-green alga Anacystis nidulans accumulates large relative amounts of two novel stable ribonucleic acid species (RNAs). These species are also made in illuminated cells but are unstable in them. When darkened cells are reilluminated, these RNAs are rapidly degraded; degradation is inhibited by chloramphenicol. Upon denaturation with heat or urea, one novel species (0.33 x 10(6) daltons) dissociates into two fragments that comigrate with the second novel species (0.16 x 10(6) daltons) on polyacrylamide gels. Both RNAs are associated with particles sedimenting between 30S and 50S through sucrose gradients and are removed from these particles at low magnesium concentration. The function(s) of these RNAs remains unknown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208132"} {"pmid": "4208131", "title": "Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: localization of uptake and of transport of transforming deoxyribonucleic acid in competent cells.", "content": "Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: localization of uptake and of transport of transforming deoxyribonucleic acid in competent cells. With the aid of serial-section electron microscopy two types of mesosomes can be distinguished in cells of competent cultures of Bacillus subtilis: (i) mesosomes connected to the plasma membrane only (plasma membrane mesosomes) and (ii) mesosomes which extend from the plasma membrane into the nuclear bodies (nuclear mesosomes). Contrary to plasma membrane mesosomes, nuclear mesosomes are absent from the tip zones. Electron microscopic autoradiography of sections of Bacillus subtilis cells exposed to [(3)H]thymidine-labeled transforming deoxyribonucleic acid (DNA) for a short period of time shows that the DNA becomes associated with mesosomes. As a function of time the DNA migrates towards the nucleoids. Transport of DNA is completed within 15 to 60 min after termination of DNA uptake. During its migration the DNA continues to be associated with mesosomes, presumably with nuclear mesosomes. DNA initially associated with plasma membrane mesosomes of the tip zones is probably transported first towards the middle zones peripherally and from there towards the nucleoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208131"} {"pmid": "4208133", "title": "An unusual mutant affecting the frequency of organelle mutation.", "content": "An unusual mutant affecting the frequency of organelle mutation. A mutant of Euglena gracilis Z is described that spontaneously produces irreversibly bleached mutants at a high frequency. Bleaching only occurs during exponential growth under highly aerobic conditions. The kinetics for bleaching and growth of bleached and nonbleached cells suggest that mutation is induced by segregation of a cellular component that becomes limiting after several culture generations. The properties of spontaneous bleaching closely resemble the properties of induced organelle mutagenesis in E. gracilis and yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208133"} {"pmid": "4208134", "title": "Outer membrane proteins of Escherichia coli. 3. Evidence that the major protein of Escherichia coli O111 outer membrane consists of four distinct polypeptide species.", "content": "Outer membrane proteins of Escherichia coli. 3. Evidence that the major protein of Escherichia coli O111 outer membrane consists of four distinct polypeptide species. Previous studies have shown that the outer membrane of Escherichia coli O111 gives a single, major, 42,000-dalton protein peak when analyzed by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis at neutral pH. Further studies have shown that this peak consists of more than a single polypeptide species, and on alkaline SDS-gel electrophoresis this single peak is resolved into three subcomponents designated as proteins 1, 2, and 3. By chromatography of solubilized, outer membrane protein on diethylaminoethyl-cellulose followed by chromatography on Sephadex G-200 in the presence of SDS, it was possible to separate the 42,000-dalton major protein into four distinct protein fractions. Comparison of cyanogen bromide peptides derived from these fractions indicated that they represented at least four distinct polypeptide species. Two of these proteins migrated as proteins 1 and 2 on alkaline gels. The other two proteins migrated as protein 3 on alkaline gels and cannot be separated by SDS-polyacrylamide gel electrophoresis. In purified form, these major proteins do not contain bound lipopolysaccharide, phospholipid, or phosphate. These proteins may contain a small amount of carbohydrate, as evidenced by the labeling of these proteins by glucosamine, and to a lesser extent by glucose, under conditions where the metabolism of these sugars to amino acids and lipids is blocked. All of the proteins were labeled to the same extent by these sugars. Thus, it was concluded that there are at least four distinct polypeptide species with apparent molecular masses of about 42,000 daltons in the outer membrane of E. coli O111.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208134"} {"pmid": "4208135", "title": "Lipoteichoic acids from Streptococcus sanguis.", "content": "Lipoteichoic acids from Streptococcus sanguis. Two lipoteichoic acids, membrane (MLTA) and wall (WLTA), have been purified from Streptococcus sanguis by Sepharose and Ecteola-cellulose column chromatographies and concanavalin A-conjugated Sepharose affinity column chromatography. The teichoic acids were homogenous as judged by disc gel electrophoresis, column chromatography, and double diffusion tests. Both MLTA and WLTA consisted of glycerol, phosphate, glucose, and fatty acids in the ratios of 0.95:1:0.71:0.046 and 0.99:1:0.79:0.023, respectively. alpha-Glycerol-phosphate was obtained by the partial acid hydrolysis of the lipoteichoic acids suggesting that their backbone structure consists of the glycerol moieties linked by 1, 3-phosphodiester bonds. Both WLTA and MLTA form aggregates, perhaps due to micelle formation, in concentrated solution. The aggregate form of MLTA dissociates to a much greater extent than that of WLTA under similar conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208135"} {"pmid": "4208136", "title": "Polyelectrolyte nature of bacterial teichoic acids.", "content": "Polyelectrolyte nature of bacterial teichoic acids. Several physicochemical properties of the teichoic acid of Bacillus subtilis 168 have been determined. The teichoic acid partial specific volume was found to be 0.57 ml/g. The apparent weight-average molecular weight of the polymer was 24,800. Sedimentation was strongly dependent on solvent. The sedimentation coefficient of the teichoic acid was found to have a value of s(20.w) (0) = 1.90S. In dilute buffers and distilled water, the teichoic acid possessed a rigid rod or extended conformation. Salts induced a loss of secondary structure in the polymer, resulting in a random coil configuration. Salt-induced structural changes in the teichoic acid were determined by viscosities, ultraviolet difference spectra, and inhibition of precipitation with concanavalin A. Divalent cations such as Mg(2+) had little effect on the teichoic acid structure. The salt-induced structural changes were reversible, as evidenced by return of the original properties upon dialysis of the teichoic acid against water. Sodium chloride inhibited the adsorption of bacteriophage ø25 to B. subtilis cell walls. Teichoic acid conformation may have a significant influence on the physiology of bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208136"} {"pmid": "4208137", "title": "Detachment and chemical characterization of the regularly arranged subunits from the surface of an Acinetobacter.", "content": "Detachment and chemical characterization of the regularly arranged subunits from the surface of an Acinetobacter. Acinetobacter sp. strain MJT/F5/199A carries an array of tetragonally arranged subunits on its outer surface. The subunits can be detached from isolated cell walls by incubation with 1 M urea or by washing with water after treatment with 10 mM ethylenediaminetetraacetic acid or ethyleneglycol-bis(beta-aminoethylether)N,N'-tetraacetic acid. After removal of the urea, they reaggregate into the same ordered array at air-water interfaces in the presence of MgCl(2). The detached subunits were characterized as an acidic protein of molecular weight 65,000. They represent one-fifth of the total cell wall protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208137"} {"pmid": "4208138", "title": "Penetration of Bdellovibrio bacteriovorus into host cells.", "content": "Penetration of Bdellovibrio bacteriovorus into host cells. Electron microscopy reveals that, in Bdellovibrio infection, after the formation of a passage pore in the host cell wall, the differentiated parasite penetration pole is associated with the host protoplast. This firm contact persists throughout the parasite penetration and after this process is completed. In penetrated hosts this contact is also apparent by phase microscopy. The association between the walls of the parasite and the host at the passage pore, on the other hand, is transient. Bdellovibrio do not penetrate hosts whose protoplast and cell walls are separated by plasmolysis, or in which the membrane-wall relationship is affected by low turgor pressure. It is concluded, therefore, that for penetration to occur it is essential that the host protoplast be within reach of the parasite, so that a firm contact can be established between them. A penetration mechanism is proposed that is effected by forces generated by fluxes of water and solutes due to structural changes in the infected host envelope. These forces cause a differential expansion of the host protoplast and cell wall and their separation from each other around the entry site, while the parasite remains firmly anchored to the host protoplast. Consequently, the parasite ends up enclosed in the expanded host periplasm. The actual entry, therefore, is a passive act of the parasite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208138"} {"pmid": "4208140", "title": "Effect of temperature on the distribution of membrane particles in Streptococcus faecalis as seen by the freeze-fracture technique.", "content": "Effect of temperature on the distribution of membrane particles in Streptococcus faecalis as seen by the freeze-fracture technique. When cells of Streptococcus faecalis ATCC 9790 were incubated at temperatures above 10 C before being frozen for freeze-fracture, a random distribution of particles was observed on the outer fracture face of the freeze-cleaved cell membrane. However, when cells were incubated below 10 C before freezing, particleless patches were seen on this membrane surface. The size of the patches produced on chilling could be increased by centrifugation or by storing the chilled cells overnight at about 3 C. Patch formation appeared readily reversible, since the medium and large patches that formed on chilling could not be observed in cells warmed for 10 s at 25 C. However, during the transition from the patch to patchless state, smaller patches not seen in the chilled cells were observed. This suggested that the smaller patches might have been intermediate forms produced by the fragmentation of larger patches on warming.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208140"} {"pmid": "4208139", "title": "Cell separation in blue-green bacteria.", "content": "Cell separation in blue-green bacteria. Autolysin-like enzymes appear to be responsible for cell separation in Agmenellum quadruplicatum. Mutants that are impaired in cell separation and grow as chains exhibit reduced cell lytic activity. Lysozyme, extracted autolysin, and antibiotics that affect peptidoglycan synthesis phenotypically suppress chain formation. Various aspects of the regulation of the cell separation process were also examined. Studies involving antibiotic inhibitors of macromolecular synthesis and general growth inhibitors provided no evidence for the active regulation of the cell separation process during the latter portion of the division cycle. Evidence was obtained, however, for the partial restriction of peptidogly-can hydrolysis by unknown secondary modifications. The thin electron-dense layer of peptidoglycan along the sides of cells was much more resistant to hydrolysis by egg-white lysozyme than was the septum between daughter cells. The middle portion of the septum was more sensitive than was the layer immediately adjacent to the cytoplasmic membrane. Under conditions that would not osmotically stabilize spheroplasts, lysozyme facilitates rapid cell separation in chain-forming mutants with little leakage of cellular protein or loss of viability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208139"} {"pmid": "4208141", "title": "The synthesis of polyribitol phosphate. II. On the mechanism of polyribitol phosphate polymerase.", "content": "The synthesis of polyribitol phosphate. II. On the mechanism of polyribitol phosphate polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208141"} {"pmid": "4208142", "title": "Unusual molecular properties of human IgG3 proteins due to an extended hinge region.", "content": "Unusual molecular properties of human IgG3 proteins due to an extended hinge region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208142"} {"pmid": "4208143", "title": "Symposium on reproduction of arthropods of medical and veterinary importance. I. Insect gametogenesis.", "content": "Symposium on reproduction of arthropods of medical and veterinary importance. I. Insect gametogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208143"} {"pmid": "4208144", "title": "Studies on the development of Rhodnius prolixus and the effects of its symbiote Nocardia rhodnii.", "content": "Studies on the development of Rhodnius prolixus and the effects of its symbiote Nocardia rhodnii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208144"} {"pmid": "4208145", "title": "Control of plague vectors on Peromyscus maniculatus by use of 2 percent carbaryl dust in bait stations.", "content": "Control of plague vectors on Peromyscus maniculatus by use of 2 percent carbaryl dust in bait stations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208145"} {"pmid": "4208149", "title": "Studies of the specificity of an antibody directed against probenecid. Investigations with probenecid analogs.", "content": "Studies of the specificity of an antibody directed against probenecid. Investigations with probenecid analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208149"} {"pmid": "4208150", "title": "Effects on drug metabolism of carbaryl and 1-naphthol in the mouse.", "content": "Effects on drug metabolism of carbaryl and 1-naphthol in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208150"} {"pmid": "4208152", "title": "The glycogen synthase system in skeletal muscle of normal humans and patients with myotonic dystrophy: effect of glucose and insulin administration.", "content": "The glycogen synthase system in skeletal muscle of normal humans and patients with myotonic dystrophy: effect of glucose and insulin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208152"} {"pmid": "4208156", "title": "Calorie supplementation and growth of pre-school children.", "content": "Calorie supplementation and growth of pre-school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208156"} {"pmid": "4208155", "title": "Fat-free parenteral alimentation of infants.", "content": "Fat-free parenteral alimentation of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208155"} {"pmid": "4208158", "title": "Letter: Adrenal regulation of protein synthesis in protein malnutrition.", "content": "Letter: Adrenal regulation of protein synthesis in protein malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208158"} {"pmid": "4208157", "title": "Metabolic effects of oral contraceptives in monkeys fed on adequate and low protein diets.", "content": "Metabolic effects of oral contraceptives in monkeys fed on adequate and low protein diets. Rhesus monkeys were given either high estrogen, low progesterone or low estrogen-high progesterone oral contraceptive agents (OCAs) and maintained on either a 16% protein diet or a 4% protein diet. Both OCAs created a small but significant fall in hemoglobin and serum protein. On both diets, OCAs led to a gradual elevation of serum alkaline phosphatase and serum glutamic oxalic transaminase (SGOT) activities. There were no histologic liver lesions. On the low protein diet, glucose tolerance was impaired between cycles 10 and 11, and on the high protein diet between cycles 16 and 20. Vitamins B-12, A, and thiamine tended to be lower in OCA animals. The conclusion of these experiments is that the hazard of using OCAs is not exaggerated by protein deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208157"} {"pmid": "4208153", "title": "A medium for rapid identification and enumeration of Aspergillus flavus and related organisms.", "content": "A medium for rapid identification and enumeration of Aspergillus flavus and related organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208153"} {"pmid": "4208164", "title": "WHO Expert Committee on Filariasis. Third report.", "content": "WHO Expert Committee on Filariasis. Third report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208164"} {"pmid": "4208165", "title": "Food-borne disease: methods of sampling and examination in surveillance programmes. Report of a WHO study group.", "content": "Food-borne disease: methods of sampling and examination in surveillance programmes. Report of a WHO study group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208165"} {"pmid": "4208166", "title": "Analysis of spore and antibiotic markers in revertants from asporogenous and sporogenous non-producer mutants of Bacillus subtilis.", "content": "Analysis of spore and antibiotic markers in revertants from asporogenous and sporogenous non-producer mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208166"} {"pmid": "4208167", "title": "Utilization of adenosine as a tool in studies on the regulation of liver glycogen biosynthesis.", "content": "Utilization of adenosine as a tool in studies on the regulation of liver glycogen biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208167"} {"pmid": "4208169", "title": "Metalloalkaline phosphatases from Bacillus subtilis: physicochemical and enzymatic properties.", "content": "Metalloalkaline phosphatases from Bacillus subtilis: physicochemical and enzymatic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208169"} {"pmid": "4208170", "title": "The physical and chemical properties of a chicken egg white glycoprotein purified by nondenaturing methodology.", "content": "The physical and chemical properties of a chicken egg white glycoprotein purified by nondenaturing methodology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208170"} {"pmid": "4208171", "title": "Studies on the mechanism of cell attachment to a substratum: evidence for three biochemically distinct processes.", "content": "Studies on the mechanism of cell attachment to a substratum: evidence for three biochemically distinct processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208171"} {"pmid": "4208172", "title": "Fructose-1,6-diphosphate aldolase from Lactobacillus casei. I. Functional similarities with the rabbit muscle aldolase.", "content": "Fructose-1,6-diphosphate aldolase from Lactobacillus casei. I. Functional similarities with the rabbit muscle aldolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208172"} {"pmid": "4208173", "title": "Fructose-1,6-diphosphate aldolase from Lactobacillus casei. II. Multiple forms and their characteristics.", "content": "Fructose-1,6-diphosphate aldolase from Lactobacillus casei. II. Multiple forms and their characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208173"} {"pmid": "4208174", "title": "Purification and properties of tyrosinases from Vibrio tyrosinaticus.", "content": "Purification and properties of tyrosinases from Vibrio tyrosinaticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208174"} {"pmid": "4208175", "title": "The fate of 2-, 3-, and 4-chlorobiphenyl following intravenous administration to the thorny skate (Raja radiata) and the winter skate (Raja ocellata).", "content": "The fate of 2-, 3-, and 4-chlorobiphenyl following intravenous administration to the thorny skate (Raja radiata) and the winter skate (Raja ocellata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208175"} {"pmid": "4208176", "title": "Tissue modifications in monkeys as related to absorption, distribution, and excretion of polychlorinated biphenyls.", "content": "Tissue modifications in monkeys as related to absorption, distribution, and excretion of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208176"} {"pmid": "4208180", "title": "Supratentorial tuberculoma: a case report and review.", "content": "Supratentorial tuberculoma: a case report and review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208180"} {"pmid": "4208179", "title": "Absorption of anticonvulsants after jejunoileal bypass.", "content": "Absorption of anticonvulsants after jejunoileal bypass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208179"} {"pmid": "4208181", "title": "Letter: Treatment of angina pectoris.", "content": "Letter: Treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208181"} {"pmid": "4208182", "title": "Letter: Treatment of angina pectoris.", "content": "Letter: Treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208182"} {"pmid": "4208183", "title": "Renal tubular function in asthmatic children on long-term disodium cromoglycate.", "content": "Renal tubular function in asthmatic children on long-term disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208183"} {"pmid": "4208184", "title": "A study of the effect of betahistine on gastric acid secretion in man.", "content": "A study of the effect of betahistine on gastric acid secretion in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208184"} {"pmid": "4208178", "title": "Bacteria isolated from imported salted duck eggs.", "content": "Bacteria isolated from imported salted duck eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208178"} {"pmid": "4208188", "title": "Neuronal activity in the chronic and acute epileptogenic focus.", "content": "Neuronal activity in the chronic and acute epileptogenic focus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208188"} {"pmid": "4208189", "title": "Trunk rigidity and limb hypotonia produced in squirrel monkeys by direct cholinergic stimulation of the globus pallidus.", "content": "Trunk rigidity and limb hypotonia produced in squirrel monkeys by direct cholinergic stimulation of the globus pallidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208189"} {"pmid": "4208190", "title": "Cells of origin of the spinocervical tract in the monkey.", "content": "Cells of origin of the spinocervical tract in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208190"} {"pmid": "4208177", "title": "Cholesteryl ester metabolism in liver and blood plasma of various animal species.", "content": "Cholesteryl ester metabolism in liver and blood plasma of various animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208177"} {"pmid": "4208191", "title": "Epileptic neurons during sleep and wakefulness.", "content": "Epileptic neurons during sleep and wakefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208191"} {"pmid": "4208192", "title": "Effects of visual cortical lesions upon ambulatory and static localization of light in space.", "content": "Effects of visual cortical lesions upon ambulatory and static localization of light in space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208192"} {"pmid": "4208193", "title": "Rheumatoid factor in a series of 155 subjects with paraproteinaemia of the main immunoglobulin classes.", "content": "Rheumatoid factor in a series of 155 subjects with paraproteinaemia of the main immunoglobulin classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208193"} {"pmid": "4208194", "title": "Pre-institutionalization factors as predictors of adjustment to a long-term care facility.", "content": "Pre-institutionalization factors as predictors of adjustment to a long-term care facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208194"} {"pmid": "4208195", "title": "Isolation procedure for bacterial DNA based on gel permeation chromatography on a sepharose column.", "content": "Isolation procedure for bacterial DNA based on gel permeation chromatography on a sepharose column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208195"} {"pmid": "4208196", "title": "Interactions of sulfonylureas with plasma proteins.", "content": "Interactions of sulfonylureas with plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208196"} {"pmid": "4208197", "title": "Selenium heterocycles. X. Synthesis and antibacterial activity of pyridyl-1,2,3-thiadiazoles and pyridyl-1,2,3-selenadiazoles.", "content": "Selenium heterocycles. X. Synthesis and antibacterial activity of pyridyl-1,2,3-thiadiazoles and pyridyl-1,2,3-selenadiazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208197"} {"pmid": "4208199", "title": "Mild chymotryptic cleavage of human IgG and its major subclasses.", "content": "Mild chymotryptic cleavage of human IgG and its major subclasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208199"} {"pmid": "4208200", "title": "Complex formation between monoclonal IgM and albumin.", "content": "Complex formation between monoclonal IgM and albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208200"} {"pmid": "4208201", "title": "Erysipelas-like disease caused by Yersinia enterocolitica.", "content": "Erysipelas-like disease caused by Yersinia enterocolitica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208201"} {"pmid": "4208203", "title": "The prognosis of chronic staphylococcal osteomyelitis after long-term antibiotic treatment.", "content": "The prognosis of chronic staphylococcal osteomyelitis after long-term antibiotic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208203"} {"pmid": "4208202", "title": "Mumps meningoencephalitis in Stockholm. IV. Attempts at virus isolation from the urine in hospitalized mumps cases with or without diagnosed mumps meningoencephalitis.", "content": "Mumps meningoencephalitis in Stockholm. IV. Attempts at virus isolation from the urine in hospitalized mumps cases with or without diagnosed mumps meningoencephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208202"} {"pmid": "4208204", "title": "In vitro sensitivity of isolates of Pseudomonas aeruginosa to carbenicillin, gentamicin, tobramycin, and some other antibiotics.", "content": "In vitro sensitivity of isolates of Pseudomonas aeruginosa to carbenicillin, gentamicin, tobramycin, and some other antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208204"} {"pmid": "4208205", "title": "The isolation of strains of rickettsiae of the spotted fever group in Israel and their differentiation from other members of the group by immunofluorescence methods.", "content": "The isolation of strains of rickettsiae of the spotted fever group in Israel and their differentiation from other members of the group by immunofluorescence methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208205"} {"pmid": "4208206", "title": "Candida albicans antibodies in candidiasis.", "content": "Candida albicans antibodies in candidiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208206"} {"pmid": "4208207", "title": "Concentration of penicillin and tetracycline in maxillary sinus secretion after a single dose.", "content": "Concentration of penicillin and tetracycline in maxillary sinus secretion after a single dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208207"} {"pmid": "4208208", "title": "Trimethoprim in the treatment and long-term control of urinary tract infection.", "content": "Trimethoprim in the treatment and long-term control of urinary tract infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208208"} {"pmid": "4208209", "title": "Orthopaedic infections treated at an infectious disease hospital.", "content": "Orthopaedic infections treated at an infectious disease hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208209"} {"pmid": "4208210", "title": "An evaluation of the genetic structure of a Drosophila melanogaster population with respect to the characteristic radius incompletus. I. Change in characteristic caused by selection.", "content": "An evaluation of the genetic structure of a Drosophila melanogaster population with respect to the characteristic radius incompletus. I. Change in characteristic caused by selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208210"} {"pmid": "4208211", "title": "The effect of boron on the nucleolus, chromocenter, and chromosomes of Drosophila melanogaster salivary gland cells.", "content": "The effect of boron on the nucleolus, chromocenter, and chromosomes of Drosophila melanogaster salivary gland cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208211"} {"pmid": "4208212", "title": "Investigation of the operon of riboflavin biosynthesis in Bacillus subtilis. 3. Production and properties of mutants with a complex regulator genotype.", "content": "Investigation of the operon of riboflavin biosynthesis in Bacillus subtilis. 3. Production and properties of mutants with a complex regulator genotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208212"} {"pmid": "4208224", "title": "Ectopic atrial rhythms in the primate.", "content": "Ectopic atrial rhythms in the primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208224"} {"pmid": "4208227", "title": "Effect of hemorrhagic shock on capillary transport in dog skeletal muscle.", "content": "Effect of hemorrhagic shock on capillary transport in dog skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208227"} {"pmid": "4208228", "title": "Studies on the antithrombotic effect of dextran effect on platelet 5-hydroxytryptamine and adenine nucleotides.", "content": "Studies on the antithrombotic effect of dextran effect on platelet 5-hydroxytryptamine and adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208228"} {"pmid": "4208229", "title": "Study on the acute effects of O-(beta-hydroxyethyl)-rutoside (HR) on the increased muscle capillary permeability in long-term diabetics.", "content": "Study on the acute effects of O-(beta-hydroxyethyl)-rutoside (HR) on the increased muscle capillary permeability in long-term diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208229"} {"pmid": "4208230", "title": "Betahistine HCL antagonism upon neural influence on microcirculation.", "content": "Betahistine HCL antagonism upon neural influence on microcirculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208230"} {"pmid": "4208231", "title": "Effects of O-(beta-hydroxyethyl)-rutosides (HR) and indomethacin on transcapillary macromolecular transport and prostaglandins following scalding injury.", "content": "Effects of O-(beta-hydroxyethyl)-rutosides (HR) and indomethacin on transcapillary macromolecular transport and prostaglandins following scalding injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208231"} {"pmid": "4208232", "title": "Vascular and extravascular spaces in two transplantable tumors of the rat.", "content": "Vascular and extravascular spaces in two transplantable tumors of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208232"} {"pmid": "4208233", "title": "Characterization of rat liver lysosomal cathepsin A1.", "content": "Characterization of rat liver lysosomal cathepsin A1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208233"} {"pmid": "4208234", "title": "Purification and properties of cathepsin D from human erythrocytes.", "content": "Purification and properties of cathepsin D from human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208234"} {"pmid": "4208235", "title": "Studies on the lipase of Chromobacterium viscosum. 3. Purification of a low molecular weight lipase and its enzymatic properties.", "content": "Studies on the lipase of Chromobacterium viscosum. 3. Purification of a low molecular weight lipase and its enzymatic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208235"} {"pmid": "4208236", "title": "Purification and properties of a nitrate reductase-inactivating enzyme.", "content": "Purification and properties of a nitrate reductase-inactivating enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208236"} {"pmid": "4208237", "title": "Interaction of bovine carbonic anhydrase with acetate ions.", "content": "Interaction of bovine carbonic anhydrase with acetate ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208237"} {"pmid": "4208226", "title": "The molecular basis of contractility. I.", "content": "The molecular basis of contractility. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208226"} {"pmid": "4208238", "title": "NMR studies of the two binding sites of acetate ions to manganese(II) carbonic anhydrase.", "content": "NMR studies of the two binding sites of acetate ions to manganese(II) carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208238"} {"pmid": "4208239", "title": "The identification of the forms of folate found in the liver, kidney and intestine of the monkey and their biosynthesis from exogenous pteroylglutamate (folic acid).", "content": "The identification of the forms of folate found in the liver, kidney and intestine of the monkey and their biosynthesis from exogenous pteroylglutamate (folic acid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208239"} {"pmid": "4208240", "title": "Antibodies to indolealkylamines: serotonin and melatonin.", "content": "Antibodies to indolealkylamines: serotonin and melatonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208240"} {"pmid": "4208241", "title": "The transfer of glucose to steroids by sheep liver microsomes.", "content": "The transfer of glucose to steroids by sheep liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208241"} {"pmid": "4208242", "title": "The 4.5 Angstrom resolution structure of a bacterial serine protease from Streptomyces griseus.", "content": "The 4.5 Angstrom resolution structure of a bacterial serine protease from Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208242"} {"pmid": "4208243", "title": "Biosynthesis of the diguanosine nucleotides. I. Purification and properties of an enzyme from yolk platelets of brine shrimp embryos.", "content": "Biosynthesis of the diguanosine nucleotides. I. Purification and properties of an enzyme from yolk platelets of brine shrimp embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208243"} {"pmid": "4208245", "title": "A rapid quantitative microtitration of Pseudomonas aeruginosa antibody.", "content": "A rapid quantitative microtitration of Pseudomonas aeruginosa antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208245"} {"pmid": "4208244", "title": "The effect of the amount of nucleic acid load on hydroxylapatite chromatography.", "content": "The effect of the amount of nucleic acid load on hydroxylapatite chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208244"} {"pmid": "4208246", "title": "Serological survey of Pseudomonas aeruginosa strains isolated from patients in Canadian hospitals.", "content": "Serological survey of Pseudomonas aeruginosa strains isolated from patients in Canadian hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208246"} {"pmid": "4208247", "title": "Glycerol ester hydrolase, lipase, of Myxococcus xanthus FB.", "content": "Glycerol ester hydrolase, lipase, of Myxococcus xanthus FB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208247"} {"pmid": "4208248", "title": "New data on the taxonomy of the Brazilian marmosets of the genus Callithrix Erxleben, 1777.", "content": "New data on the taxonomy of the Brazilian marmosets of the genus Callithrix Erxleben, 1777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208248"} {"pmid": "4208249", "title": "Heart rate (radiotelemetrical registration) in macaques and baboons according to dominant-submissive rank in a group.", "content": "Heart rate (radiotelemetrical registration) in macaques and baboons according to dominant-submissive rank in a group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208249"} {"pmid": "4208250", "title": "Maternal-fetal weight relationships in primates.", "content": "Maternal-fetal weight relationships in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208250"} {"pmid": "4208251", "title": "The effect of corpora allata on the plasma membrane of the symbiotic bacteria of the oocyte surface of Periplaneta americana L.", "content": "The effect of corpora allata on the plasma membrane of the symbiotic bacteria of the oocyte surface of Periplaneta americana L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208251"} {"pmid": "4208256", "title": "Influence of growth conditions on the composition of some streptococcal amino acid pools.", "content": "Influence of growth conditions on the composition of some streptococcal amino acid pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208256"} {"pmid": "4208268", "title": "Spinal cord blood flow in the rhesus monkey by the hydrogen clearance method.", "content": "Spinal cord blood flow in the rhesus monkey by the hydrogen clearance method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208268"} {"pmid": "4208269", "title": "Studies on dentin. I. Mantle dentin.", "content": "Studies on dentin. I. Mantle dentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208269"} {"pmid": "4208270", "title": "Studies on plasma somatomedin activity in different animal species.", "content": "Studies on plasma somatomedin activity in different animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208270"} {"pmid": "4208271", "title": "Parathyroid hormone secretion in disorders of calcium metabolism studied by means of EDTA.", "content": "Parathyroid hormone secretion in disorders of calcium metabolism studied by means of EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208271"} {"pmid": "4208272", "title": "The changing scene in public health: Delta Omega Lecture.", "content": "The changing scene in public health: Delta Omega Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208272"} {"pmid": "4208273", "title": "Cross-resistance and collateral susceptibility to antifolic antimalarial compounds.", "content": "Cross-resistance and collateral susceptibility to antifolic antimalarial compounds. Series of strains of Streptococcus faecium ATCC 8043, Lactobacillus casei ATCC 7469, and Pediococcus cerevisiae ATCC 8081 with increasing resistance to the active antifolate antimalarial drugs chlorguanide triazine (CGT), pyrimethamine (PM), and trimethoprim (TMP) were isolated. These mutant strains, stable for at least 3 to 5 years, were examined for cross-resistance and collateral susceptibility to the above compounds and to methotrexate (MTX). Generally, they exhibited cross-resistance to all four compounds, but resistance of a strain to one compound did not predict accurately its resistance to another drug. Unexpectedly, L. casei resistant to CGT exhibited collateral susceptibility to MTX, TMP, and PM varying from 5- to 20-fold. P. cerevisiae developed resistance to CGT readily but maintained its susceptibility to PM and TMP after prolonged exposure to these compounds. Resistance to these antimalarial antifolates was accompanied by only low-grade cross-resistance to MTX, a representative antileukemic antifolate agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208273"} {"pmid": "4208274", "title": "Mechanisms and spectrum of streptomycin resistance in a natural population of Pseudomonas aeruginosa.", "content": "Mechanisms and spectrum of streptomycin resistance in a natural population of Pseudomonas aeruginosa. A survey of 200 strains of Pseudomonas aeruginosa isolated from clinical specimens was made in an attempt to correlate the spectrum of their streptomycin resistance and the mechanism of resistance. The strains can be classified into three groups, according to their level of resistance to streptomycin: susceptible, low-level resistant, and high-level resistant strains. The mechanism of resistance of high-level resistant strains is either an R factor-mediated inactivation of streptomycin by phosphorylation or streptomycin-resistant ribosomes. However, such high-level resistant strains comprised less than 10% of the total strains isolated; the majority of the strains resistant to streptomycin were of low-level resistance. The latter are associated with a diminished uptake of streptomycin, and no evidence of streptomycin inactivation, resistant ribosomes, or R factors could be detected. The most probable explanation of low-level resistance is reduced permeability to streptomycin. Modification of the growth medium used in uptake studies simultaneously affected strongly both streptomycin incorporation and the minimal inhibitory concentration of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208274"} {"pmid": "4208275", "title": "Comparison of tobramycin, gentamicin, colistin, and carbenicillin in Pseudomonas sepsis in monkeys.", "content": "Comparison of tobramycin, gentamicin, colistin, and carbenicillin in Pseudomonas sepsis in monkeys. Intravenous inoculation of 3.4 x 10(10) to 7.4 x 10(10)Pseudomonas aeruginosa organisms into rhesus monkeys 4 days after intravenous or intratracheal inoculation of 2.0 to 2.5 mg of vincristine sulfate resulted in fatal sepsis in eight of nine monkeys. After intramuscular administration, in two equal doses, of 5 mg of tobramycin, gentamicin, and colistin per kg per day beginning 16 hr after challenge, 4 of 11, 4 of 11, and 3 of 10 monkeys died, respectively. Administration of daily doses of 100 to 400 mg of carbenicillin per kg was followed by death in 5 of 12. Duration of illness in the surviving monkeys in each therapy group was similar. Under the conditions of this study, prior administration of vincristine sulfate resulted in a decrease in leukocytes and enhanced susceptibility to Pseudomonas infection. Using this model for studies of comparative efficacy of antibiotics, we observed comparable results after treatment with tobramycin, gentamicin, colistin, and carbenicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208275"} {"pmid": "4208277", "title": "Inhibition of chlorination in Streptomyces aureofaciens by nitriles and related compounds.", "content": "Inhibition of chlorination in Streptomyces aureofaciens by nitriles and related compounds. A number of nitriles and cyano compounds inhibited chlorination by Streptomyces aureofaciens. In most cases, this inhibition was enhanced by bromide. Methylene blue and p-amino-propiophenone reversed the inhibition to some extent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208277"} {"pmid": "4208276", "title": "Comparison of colistin-carbenicillin, colistin, and carbenicillin in Pseudomonas sepsis in monkeys.", "content": "Comparison of colistin-carbenicillin, colistin, and carbenicillin in Pseudomonas sepsis in monkeys. Intravenous inoculation of 6.2 x 10(10) to 6.7 x 10(10)Pseudomonas aeruginosa organisms into rhesus monkeys 5 days after intratracheal inoculation of 2.0 to 2.5 mg of vincristine sulfate resulted in fatal sepsis in 8 of 10 untreated monkeys. When similarly infected monkeys were treated intramuscularly with 2.5 mg of colistin or 50 mg of carbenicillin per kg per day, all three monkeys in each treatment group survived; one of three monkeys receiving both antibiotics at the above doses died. Six of seven monkeys treated with 1.25 mg of colistin per kg per day and three of seven treated with 25 mg of carbenicillin per kg per day died; four of nine monkeys receiving both antibiotics at these doses died. A combination of the data obtained at both dose levels tested shows that 6 of 10, 3 of 10, and 5 of 12 monkeys, respectively, died after treatment with colistin, carbenicillin, and the colistin-carbenicillin combination. Antibacterial activity of serum from both infected and normal monkeys was not appreciably different when the two antibiotics were given singly or in combination. Under the conditions of this study and with the doses employed, the response of monkeys treated with the antibiotic combination did not differ significantly from that of monkeys treated with a single agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208276"} {"pmid": "4208278", "title": "Biliary excretion of a new semisynthetic cephalosporin, cephacetrile.", "content": "Biliary excretion of a new semisynthetic cephalosporin, cephacetrile. The biliary excretion of a new derivative of cephalosporin, cephacetrile (CIBA 36 278 Ba), was studied (i) in the isolated perfused rabbit liver, (ii) in humans with a duodenal tube, and (iii) in patients after cholecystectomy with a Kehr's drain in the common bile duct. The biliary excretion of the antibiotic was very low in the perfused liver, and no antibiotic activity was found in liver tissue at the end of the experiment. This observation, together with the finding of a rapid decline of the antibiotic concentration in the circulating blood serum, favors the assumption that a metabolic transformation of CIBA 36 278 Ba in liver tissue takes place. In humans, the antibiotic concentration was found to be low both in the duodenal juice and in the bile obtained by external drainage. The biliary concentrations found in these subjects seem to be inferior to those required for the inhibition of the common bacteria of biliary infections. In renal failure, however, the biliary excretion of CIBA 36 278 Ba increased considerably.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208278"} {"pmid": "4208279", "title": "A9145, a new adenine-containing antifungal antibiotic: fermentation.", "content": "A9145, a new adenine-containing antifungal antibiotic: fermentation. A9145 is a basic, water-soluble, antifungal antibiotic which is produced in a complex organic medium by Streptomyces griseolus. The metabolite has a molecular weight of 510, and contains adenine as well as sugar hydroxyl and amino groups. Although glucose, fructose, glucose polymers, and some long-chain fatty acid methyl esters supported biosynthesis, oils were superior, with cottonseed oil being preferred. Several ions and salts, especially Co(2+), PO(4) (3-), and CaCO(3), were stimulatory. Adenine, nucleosides, and some amino acids increased the accumulation of A9145 in shaken-flask fermentors. Enrichment of the culture medium with tyrosine afforded maximal enhancement of antibiotic production in both flask and tank fermentors. Control of the dissolved O(2) level was also critical, the optimal concentration being 3 x 10(-2) to 4.5 x 10(-2) mumole of O(2)/ml. Optimization of various fermentation parameters increased antibiotic titers approximately 135-fold in shaken flask fermentors and 225-fold in stirred vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208279"} {"pmid": "4208280", "title": "Cation reversal of inhibition of growth by valinomycin in Streptococcus pyogenes and Clostridium sporogenes.", "content": "Cation reversal of inhibition of growth by valinomycin in Streptococcus pyogenes and Clostridium sporogenes. Study of the antimicrobial spectrum of valinomycin revealed that, in addition to the gram-positive bacteria reported in literature, Streptococcus pyogenes and Clostridium sporogenes are also susceptible to this antibiotic. The minimal inhibitory concentrations (MIC) of the antibiotic for S. pyogenes grown aerobically and anaerobically did not differ markedly, negating the hypothesis that oxidative phosphorylation is involved in the mechanism of action of this antibiotic. This conclusion is further strengthened by the inhibition of growth of C. sporogenes, an obligate anaerobe. In a medium with a low K(+) concentration, the MIC for S. pyogenes was 0.02 mug/ml, the lowest ever recorded for this antibiotic. The inhibition of growth of S. pyogenes and C. sporogenes was readily reversed by addition of K(+) to the medium, indicating a compensation for net efflux of K(+) from the cells when the transmembrane potential reached equilibrium. In contrast to these bacteria, Bacillus subtilis was less susceptible to the antibiotic when the potassium concentration of the medium was low. The addition of potassium in the presence of valinomycin increased the inhibition of growth, which appears to result from dissipation of metabolic energy as in the mitochondrial system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208280"} {"pmid": "4208282", "title": "Amoxicillin, a new penicillin antibiotic.", "content": "Amoxicillin, a new penicillin antibiotic. Amoxicillin (alpha-amino-p-hydroxybenzyl penicillin, BRL 2333) is a new semisynthetic penicillin which is structurally similar to ampicillin, but which is better absorbed and yields higher concentrations in serum and urine. The in vitro susceptibility of 145 strains of Enterobacteriaceae and 30 isolates of Pseudomonas aeruginosa was determined against various concentrations of amoxicillin and ampicillin in agar. In addition, inhibitory zones around discs containing 10 mug of amoxicillin were measured and compared with results of agar dilution studies. The drug also was evaluated in the treatment of 38 patients with bacteriuria, who received doses of either 750 mg or 1 g/day for 10 days. In vitro, amoxicillin was comparable in activity to ampicillin; most isolates of Escherichia coli and Proteus mirabilis were inhibited by 10 mug or less/ml, whereas the majority of strains of Enterobacter, Klebsiella, indole-positive Proteus species, and Pseudomonas grew in concentrations greater than 50 mug/ml. Clinically, amoxicillin was effective in eradicating bacteriuria due to susceptible organisms and was very well tolerated. For practical purposes, however, amoxicillin performed no better than a host of other drugs presently available for the treatment of acute, uncomplicated bacteriuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208282"} {"pmid": "4208281", "title": "In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.", "content": "In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses. Virazole (1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a highly soluble new synthetic nucleoside having significant, reproducible activity against a broad spectrum of deoxyribonucleic acid and ribonucleic acid viruses in vitro. The drug inhibited viral cytopathogenic effects in monolayers of cells infected for 3 days with type 3 adeno, types 1 and 2 herpes, myxoma, cytomegalo, vaccinia, infectious bovine rhinotracheitis, types 1A, 2, 8, 13, and 56 rhino, types 1 and 3 parainfluenza, vesicular stomatitis, subacute sclerosing panencephalitis, Semliki Forest, Newcastle disease, and measles viruses. Hemagglutinin production by influenza A(2), influenza B, and type 1 parainfluenza viruses in chicken embryo cells was reduced by Virazole treatment. Recoverable intra- and extracellular virus titers were reduced by the drug in experiments with type 1 herpes, vaccinia, type 3 parainfluenza, and vesicular stomatitis viruses. Plaque formation by type 1 herpesvirus was also inhibited by exposure of the infected cells to Virazole. Pretreatment of cells with the compound, followed by its removal before addition of type 1 herpesvirus, severely lessened the antiviral activity; the compound was still moderately effective in reducing the viral effects on the cells when added as long as 22 hr after the virus. Parallel experiments, in which the antiviral activity of a number of known active drugs was compared, indicated Virazole to have at least a comparable degree of activity, and it was also active against a wider variety of viruses than any of these known active materials. The CCED(50) of Virazole to chicken embryo cells was approximately 1,000 mug/ml, although concentrations as low as 10 mug/ml caused slight (15%) inhibition in total cellular protein after 72 hr of incubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208281"} {"pmid": "4208283", "title": "Comparison of gentamicin, carbenicillin and gentamicin, and carbenicillin in Pseudomonas sepsis in monkeys.", "content": "Comparison of gentamicin, carbenicillin and gentamicin, and carbenicillin in Pseudomonas sepsis in monkeys. Intravenous inoculation of 6.0 x 10(10)Pseudomonas aeruginosa organisms into rhesus monkeys 4 days after intratracheal inoculation of 2.5 mg of vincristine sulfate resulted in fatal sepsis in all of three untreated control monkeys. After intramuscular administration of either 2.5 mg of gentamicin or 50 mg of carbenicillin per kg per day, three of four monkeys in each group survived. When both antibiotics were given at the same dose but in separate sites, six of eight monkeys survived. Antibacterial activity of serum from infected monkeys or normal monkeys was not appreciably different when the two antibiotics were combined. Under the conditions of this study, there was no apparent difference in response of monkeys treated either with gentamicin or carbenicillin alone or with the combination of the two antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208283"} {"pmid": "4208284", "title": "Molecular characterization of the R factors implicated in the carbenicillin resistance of a sequence of Pseudomonas aeruginosa strains isolated from burns.", "content": "Molecular characterization of the R factors implicated in the carbenicillin resistance of a sequence of Pseudomonas aeruginosa strains isolated from burns. An outbreak of R-factor-mediated carbenicillin resistance in Pseudomonas aeruginosa in burned patients in March 1969 was followed by a second outbreak 6 months later. No R-factor-carrying P. aeruginosa strains were detected in the intervening period but R-factor-determined lactamase was commonly encountered, particularly in Klebsiella aerogenes strains. A comparison of the molecular properties of the R factors in pseudomonads from the first and second phases with those in the Klebsiella strains from the intervening period showed them to be very closely related. A single R-factor type therefore may have been maintained in the Burns Unit between the two Pseudomonas outbreaks as a plasmid conferring resistance to ampicillin in K. aerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208284"} {"pmid": "4208285", "title": "Discrepancy between carbenicillin and ampicillin activities against enterococci and Listeria.", "content": "Discrepancy between carbenicillin and ampicillin activities against enterococci and Listeria. For infections of the newborn, carbenicillin has theoretical advantages over ampicillin, when given with an aminoglycoside, because of its activity against Pseudomonas and many indole-positive Proteus strains. Agar and broth dilution susceptibility studies demonstrated comparable activities of carbenicillin and ampicillin against coliform organisms but greater resistance of enterococci and Listeria to carbenicillin. However, the significance of the higher inhibitory concentrations is questionable because many serum specimens containing concentrations of carbenicillin lower than the minimal bactericidal values for Listeria and enterococcus strains had demonstrable in vitro bactericidal activity. Carbenicillin and gentamicin combinations had greater antibacterial activities than either drug alone against all enterococci tested and against 50% of Listeria strains. The questions of efficacy raised by contradictory in vitro data may be answered by clinical studies of carbenicillin and gentamicin in infections of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208285"} {"pmid": "4208286", "title": "Mode of action illudin S.", "content": "Mode of action illudin S. The effect of the antitumor antibiotic illudin S on bacterial macromolecular synthesis was investigated. Illudin S was found to be inhibitory to in vivo deoxyribonucleic acid (DNA) synthesis from thymidine. Ribonucleic acid (RNA) synthesis was inhibited only at a concentration of illudin S 10 times that which inhibited DNA synthesis. The rate of protein synthesis remained the same except for a brief initial inhibition. When thymidine triphosphate was used for in vitro DNA synthesis, inhibition by illudin S did not occur, as tested with partially purified DNA polymerase II from Escherichia coli pol A(1) (-), with E. coli DNA-dependent RNA polymerase, with E. coli pol A(1) (-) spheroplasts, and with frozen and thawed Bacillus subtilis cells. A protein fraction isolated from B. subtilis capable of forming thymidine mono-, di-, and triphosphates from thymidine was not inhibited by illudin S. Furthermore, (14)C-illudin S taken up by B. subtilis cells was reisolated unchanged, making an intracellular activation of illudin S unlikely. Therefore, an attractive hypothesis is that illudin S inhibits DNA synthesis from thymidine which does not proceed through deoxyribonucleoside triphosphates, the generally accepted substrates for DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208286"} {"pmid": "4208287", "title": "Interaction between deoxyribonucliec acid and distamycin A studied by transformation in Bacillus subtilis.", "content": "Interaction between deoxyribonucliec acid and distamycin A studied by transformation in Bacillus subtilis. Distamycin A inhibits deoxyribonucleic acid (DNA)-mediated transformation and transfection in Bacillus subtilis at doses with little or no antibacterial effect. The inhibition of transformation parallels the inhibition of DNA uptake; further-more, during the transformation process, donor DNA molecules become distamycin and deoxyribonuclease resistant at the same time. This demonstrates that the drug acts by inhibiting DNA uptake. Although the drug is known to bind DNA, the inhibition is not related to affinity of the drug for DNA. This is shown by the lack of dependence of the extent of inhibition on DNA concentration, whereas the degree of inhibition depends upon cell concentration. Supporting this view is the fact that transformation by single-stranded DNA was also inhibited, even though the drug does not bind to denatured DNA. Distamycin A probably interferes with transformation by competing with DNA for some unknown bacterial component involved in transport of DNA into the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208287"} {"pmid": "4208288", "title": "Susceptibility of whole cells and spheroplasts of Pseudomonas aeruginosa to actinomycin D.", "content": "Susceptibility of whole cells and spheroplasts of Pseudomonas aeruginosa to actinomycin D. Cells of Pseudomonas aeruginosa suspended in 0.2 M Mg(2+), 20% sucrose, 0.01 M tris(hydroxymethyl)aminomethane, or water partially release lipopolysaccharide. The release of alkaline phosphatase from the periplasmic space and the ability to form spheroplasts on lysozyme treatment is directly related to the lipopolysaccharide released during treatment with 0.2 M Mg(2+), 20% sucrose, or other agents. The synthesis of ribonucleic acid (RNA) by intact cells, magnesium-lysozyme spheroplasts, or 20% sucrose-lysozyme spheroplasts is not sensitive to actinomycin D, whereas RNA synthesis by intact cells or spheroplasts in the presence of ethylene-diaminetetraacetic acid (EDTA) is sensitive to actinomycin D. EDTA alone has an inhibitory effect on RNA synthesis by whole cell, by magnesium-lysozyme spheroplasts, and by 20% sucrose-lysozyme spheroplasts. The experimental data indicate that, although the cell wall is damaged by 0.2 M Mg(2+) or 20% sucrose treatment in the presence of lysozyme, the treated cells or spheroplasts are still resistant to actinomycin D. These results suggest that the cytoplasmic membrane should be considered as the final and determinative barrier to this antibiotic in this organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208288"} {"pmid": "4208289", "title": "Pharmacokinetic studies of tobramycin and gentamicin.", "content": "Pharmacokinetic studies of tobramycin and gentamicin. Broth dilution susceptibility tests of 100 isolates of Pseudomonas aeruginosa and 101 isolates of Staphylococcus aureus against tobramycin (formerly nebramycin factor 6) and gentamicin showed that tobramycin was more effective against P. aeruginosa and less effective against S. aureus. The minimal inhibitory concentration of tobramycin against the Pseudomonas sp. isolates that required 5 mug of gentamicin per ml for inhibition ranged from 0.63 to 0.31 mug/ml. Peak concentrations in the blood of 10 healthy adults after intramuscular injection of 80 and 40 mg of tobramycin averaged 3.7 +/- 0.62 and 2.4 +/- 0.27 mug/ml, and declined to 0.56 +/- 0.05 and 0.26 +/- 0.02 mug/ml, respectively, after 6 h. The urine recovery averaged 60%. The half-life was 1.6 h. During continuous intravenous infusion of tobramycin and gentamicin (infusion rate 6.6 mg per h), blood levels at steady state were 0.94 +/- 0.10 and 1.04 +/- 0.06 mug/ml, respectively. For both antibiotics, the calculated distribution volume ranged from 15 to 17 liters. The renal clearance to tobramycin averaged 76% and that of gentamicin averaged 85% of the total clearance, indicating that the drugs are primarily eliminated by the kidneys. The present results suggest that tobramycin may be more successful in the treatment of Pseudomonas infections than gentamicin at the same dosage (80 mg intramuscularly three to four times daily).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208289"} {"pmid": "4208290", "title": "Pharmacokinetics of the aminoglycoside antibiotic tobramycin in humans.", "content": "Pharmacokinetics of the aminoglycoside antibiotic tobramycin in humans. The pharmacokinetics, distribution, and plasma and renal clearance of a new aminoglycoside antibiotic, tobramycin, was studied in the treatment of 18 elderly male patients (average age, 69 years) with urinary tract infections. Ten of these patients had normal renal function and eight had impaired renal function of various degrees. After administration of 1 mg of tobramycin/kg of body weight every 6 to 8 h (two to three times the half-life), urine concentrations were found to be sufficient in the treatment of urinary tract infections caused by susceptible organisms. The renal clearance of tobramycin during constant intravenous infusion was also studied in eight patients. Good correlation was found between the patients serum creatinine and the half-life of tobramycin. The half-life of tobramycin in patients with normal renal function (serum creatine [Formula: see text] to 1.5 mg/100) was on the average 3 h. For practical purposes, therefore, the dosage of tobramycin in the treatment of urinary tract infections should be 1 mg/kg of body weight every 6 to 8 h in patients with normal renal function. For patients with impaired renal function, the dosage interval is calculated by multiplying the patients' serum creatinine by six. If the dosage intervals are kept unchanged, the dosage must be divided by the patients' serum creatinine. The initial loading dose should always be 1 mg/kg. The total renal clearance of tobramycin (92% of the glomerular filtration rate) was not influenced by the administration of probenecid, which indicates that tobramycin is excreted only by glomerular filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208290"} {"pmid": "4208291", "title": "Increased susceptibility of Neisseria gonorrhoea from a rural area.", "content": "Increased susceptibility of Neisseria gonorrhoea from a rural area. The in vitro susceptibility of 18 to 24 isolates of Neisseria gonorrhoea were tested against 12 different antimicrobial agents. These isolates represent all of the gonococcal organisms which had been isolated by the bacteriology laboratory of the Vermont State Department of Health from 1 March to 31 July 1972 and originated from patients cultured in Vermont. These isolates were considerably more susceptible to penicillin G and tetracycline than are current isolates from elsewhere in the United States and Canada. Possible explanations for this difference are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208291"} {"pmid": "4208292", "title": "Penicillin-tobramycin synergism against enterococci: a comparison with penicillin and gentamicin.", "content": "Penicillin-tobramycin synergism against enterococci: a comparison with penicillin and gentamicin. Combinations of penicillin plus tobramycin have been compared with penicillin plus gentamicin against 27 strains of enterococci isolated from blood cultures. Penicillin plus gentamicin was synergistic against all strains. The combination of penicillin plus tobramycin was equally effective against strains of Streptococcus facalis, but was ineffective against all four strains of S. faecium tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208292"} {"pmid": "4208293", "title": "Chloroquine-resistant Plasmodium falciparum: difference in the handling of 14C-amodiaquin and 14C-chloroquine.", "content": "Chloroquine-resistant Plasmodium falciparum: difference in the handling of 14C-amodiaquin and 14C-chloroquine. (14)C-amodiaquin and (14)C-chloroquine were used to study drug binding by preparations of owl monkey erythrocytes infected either with a chloroquine-susceptible (CS) or with a chloroquine-resistant (CR) strain of P. falciparum. Both of these drugs are derivatives of 4-aminoquinoline, but they differ in their side chains, and there are differences in the way they are handled by preparations of erythrocytes infected with malaria parasites. Although the apparent association constant for the binding of either drug is approximately 10(7) mol(-1), two to three times more radioactivity was bound from (14)C-amodiaquin than from (14)C-chloroquine. Furthermore, there was no apparent difference between CS and CR parasites with respect to (14)C-amodiaquin binding, whereas erythrocytes infected with CR parasites have a deficiency of (14)C-chloroquine binding. This difference in the handling of amodiaquin probably accounts for its superiority in the treatment of the owl monkey and of humans infected with CR P. falciparum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208293"} {"pmid": "4208294", "title": "Silver sulfadiazine: effect on the ultrastructure of Pseudomonas aeruginosa.", "content": "Silver sulfadiazine: effect on the ultrastructure of Pseudomonas aeruginosa. Pseudomonas aeruginosa exposed to silver sulfadiazine (AgSu) were examined in an electron microscope. The treated cells were distorted in shape, and structures (blebs) protruded from the cell surface. These \"blebs\" appeared to arise from the cell wall. A strain of P. aeruginosa resistant to AgSu did not display these changes. Upon exposure of P. aeruginosa to silver nitrate, none of these changes was seen; rather, such cells are characterized by large, central aggregations of nuclear material. The results are consistent with previous findings which suggested that AgSu acted at the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208294"} {"pmid": "4208296", "title": "Mechanisms of R factor R931 and chromosomal tetracycline resistance in Pseudomonas aeruginosa.", "content": "Mechanisms of R factor R931 and chromosomal tetracycline resistance in Pseudomonas aeruginosa. The mechanism of tetracycline resistance mediated by R931 (a Pseudomonas aeruginosa R factor not yet successfully transferred to Escherichia coli recipients) was examined. In strain 931 (R931) (minimal inhibitory concentration [MIC] 200 mug/ml) significant tetracycline uptake did not occur until 100 mug of tetracycline per ml was included in uptake studies. The introduction of R931 into strain 280 resulted in a significant decline in (3)H-tetracycline uptake. In both strains 931 (R931) and 280 (R931), a further reduction in tetracycline uptake resulted from pre-incubation with 1 mug of tetracycline per ml. Tetracycline resistance in R(-)P. aeruginosa strains 1731, 1885, and 494, considered to be of chromosomal origin, was associated with a lack of tetracycline uptake until the MIC of the strain was obtained. No evidence of tetracycline inactivation or ribosomal resistance was detected in R(-) or R(+) strains. The MIC for R(-) strains was generally about 25 mug/ml and that for R(+) strains was 75 to 200 mug/ml.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208296"} {"pmid": "4208295", "title": "Characteristics of R931 and other Pseudomonas aeruginosa R factors.", "content": "Characteristics of R931 and other Pseudomonas aeruginosa R factors. R factors were detected in 3.3% of 233 hospital isolates of Pseudomonas aeruginosa using P. aeruginosa recipients in conjugations. Transferred markers included streptomycin, tetracycline, and sulfonamide resistance. Gentamicin resistance was transferred from two strains previously shown to acetylate gentamicin. A group of R factors exemplified by R931 were characterized by failure to transfer to Escherichia coli recipients. Such R factors formed a single compatibility group when examined in a P. aeruginosa recipient. Other P. aeruginosa R factors, including RP4, showed stable coexistence with the R931 group. It is proposed that RP4 and similar R factors be members of the P-1 compatibility group and that R931, R3108, R209, and R130 be members of a group termed P-2. The buoyant densities of all R factors examined were similar, about 1.716 to 1.719 g/cm(3). The content of R-factor deoxyribonucleic acid (DNA) relative to the total DNA varied among the different R factors, ranging from about 18 +/- 2% in log-phase cells of 931 (R931) to undetectable for 679 (R679). However, R679, which transferred from strain 679 at extremely low and irregular frequencies to an E. coli host, was shown to represent about 4% R-factor DNA in that host. The relative DNA content of R931 appeared to decline in the stationary growth phase of 931 (R931) or 280 (R931). R931 covalently closed circular DNA was isolated by ethidium bromide-CsCl gradient centrifugation and examined by electron microscopy. Two major molecular distributions existed, having contour lengths of 0.5 and 12.4 mum. The molecular weights were estimated to be 10(6) and 25 x 10(6). Both molecules were under relaxed replication control. R factor R931 exists as a naturally occurring high-frequency transfer system in P. aeruginosa strains 931 and 1310. However, in strain 280 it acts as if subject to fertility repression. Other members of the P-2 compatibility group also are high-frequency transfer systems in the natural host and in strain 1310. RP4 is restricted from recipient strain 1310. Some additional recipient effects were noted in that strains 1310 or 280 sometimes differed in recipient effectiveness with a given donor. Agglutination reactions with absorbed antiserum were able to distinguish between two members of the same R-factor compatibility group, R931 and R3108.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208295"} {"pmid": "4208297", "title": "Pharmacokinetic studies in animals and humans of a new cephalosporin, the sodium salt of 7-cyanacetamidocephalosporanic acid.", "content": "Pharmacokinetic studies in animals and humans of a new cephalosporin, the sodium salt of 7-cyanacetamidocephalosporanic acid. The sodium salt of 7-cyanacetamidocephalosporanic acid (CAA) had a relatively short serum half-life in rabbits (21 min by intravenous and 30 min by intramuscular administration) and in humans (33 min by intravenous injection). The drug was not extensively bound (about 35%) to serum in either species. Even after large doses (500 mg/kg), CAA was not well absorbed from the gastrointestinal tract of rabbits. Urinary excretion of antibacterial activity was rapid after intravenous and intramuscular administration in rabbits and after intravenous administration in men. Expressed as unchanged CAA, antibacterial activity appeared in the urine to the extent of 84% for humans, 35% for rabbits and 32% for rats. Excretion proceeded partly by active renal tubular secretion in rabbits. In this latter species, low concentrations of the active drug were detected in cerebrospinal fluid and bile after an intravenous dose of 25 mg/kg. CAA was well tolerated after intravenous administration of a single dose in both rabbits and humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208297"} {"pmid": "4208299", "title": "Transfection in B. subtilis.", "content": "Transfection in B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208299"} {"pmid": "4208298", "title": "Immunological recognition of polynucleotide structure.", "content": "Immunological recognition of polynucleotide structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208298"} {"pmid": "4208300", "title": "Recent advances in molecular pathology. Regression of atherosclerosis--a perspective.", "content": "Recent advances in molecular pathology. Regression of atherosclerosis--a perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208300"} {"pmid": "4208302", "title": "Effects of elevated temperature on the mycetome and symbiotes of the bed bug Cimex lectularius (Heteroptera).", "content": "Effects of elevated temperature on the mycetome and symbiotes of the bed bug Cimex lectularius (Heteroptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208302"} {"pmid": "4208301", "title": "Proceedings: Effect of growth hormone release inhibiting hormone on the release of growth hormone and other pituitary hormones in man.", "content": "Proceedings: Effect of growth hormone release inhibiting hormone on the release of growth hormone and other pituitary hormones in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208301"} {"pmid": "4208303", "title": "Effect of prolonged storage of spores on field applications of Nosema locustae (Microsporida: Nosematidae) against grasshoppers.", "content": "Effect of prolonged storage of spores on field applications of Nosema locustae (Microsporida: Nosematidae) against grasshoppers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208303"} {"pmid": "4208304", "title": "Pathological effects of Urosporidium (Haplosporida) infection in microphallid metacercariae.", "content": "Pathological effects of Urosporidium (Haplosporida) infection in microphallid metacercariae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208304"} {"pmid": "4208306", "title": "Total-body potassium and lean body mass in males with an abnormal sex chromosome complement.", "content": "Total-body potassium and lean body mass in males with an abnormal sex chromosome complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208306"} {"pmid": "4208307", "title": "The effect of sex hormones on rat liver carbonic anhydrase.", "content": "The effect of sex hormones on rat liver carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208307"} {"pmid": "4208305", "title": "The phylogeny of human globin genes investigated by the maximum parsimony method.", "content": "The phylogeny of human globin genes investigated by the maximum parsimony method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208305"} {"pmid": "4208308", "title": "Some dynamic properties of linear, hyperbolic and sigmoidal multi-enzyme systems with feedback control.", "content": "Some dynamic properties of linear, hyperbolic and sigmoidal multi-enzyme systems with feedback control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208308"} {"pmid": "4208310", "title": "Pentane production by peanut lipoxygenase.", "content": "Pentane production by peanut lipoxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208310"} {"pmid": "4208314", "title": "Studies of complement levels in normal human pregnancy.", "content": "Studies of complement levels in normal human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208314"} {"pmid": "4208315", "title": "The integrative approach in medicine--implications of neuroendocrine mechanisms.", "content": "The integrative approach in medicine--implications of neuroendocrine mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208315"} {"pmid": "4208316", "title": "Sex differences in passion and play.", "content": "Sex differences in passion and play.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208316"} {"pmid": "4208317", "title": "Sexuality and reproduction.", "content": "Sexuality and reproduction. The relationship between coital rates, a quantitative index of sexuality, and the quality and quantity of reproduction is discussed in terms of sex ratio, delayed fertilization, frequency of intercourse, intercourse distribution within the menstrual cycle, acceleration of ovulation, and the quality of intercourse. Frequency of intercourse affects chances of conception, but its effect on twinning and sex ratio are unclear. Current research on reproduction offers little evidence of the effect of intercourse quality on reproduction in fully fecund individuals; research into the possible effect on reduced fecundity would be desirable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208317"} {"pmid": "4208318", "title": "Observations on the development of antibodies to thiamine tetrahydrofurfuryl disulfide in rabbits.", "content": "Observations on the development of antibodies to thiamine tetrahydrofurfuryl disulfide in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208318"} {"pmid": "4208320", "title": "Structural organization of developing chloroplasts in Euglena.", "content": "Structural organization of developing chloroplasts in Euglena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208320"} {"pmid": "4208321", "title": "The effect of ethylenediaminetetraacetic acid on yeast cell membranes.", "content": "The effect of ethylenediaminetetraacetic acid on yeast cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208321"} {"pmid": "4208323", "title": "Pyrazapon (CI-683): a new antianxiety agent.", "content": "Pyrazapon (CI-683): a new antianxiety agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208323"} {"pmid": "4208327", "title": "Childhood asthma in Finland. A survey of 559 patients.", "content": "Childhood asthma in Finland. A survey of 559 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208327"} {"pmid": "4208328", "title": "Histochemical localization of acetylcholinesterase enzyme in the 'limbic system' of the brain of the squirrel monkey (Saimiri sciureus).", "content": "Histochemical localization of acetylcholinesterase enzyme in the 'limbic system' of the brain of the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208328"} {"pmid": "4208330", "title": "Serine neutral proteinase from Bacillus pumilus as metalloenzyme.", "content": "Serine neutral proteinase from Bacillus pumilus as metalloenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208330"} {"pmid": "4208329", "title": "Organon thalamo-chorioidalis in the taenia thalami of the cat and other mammals.", "content": "Organon thalamo-chorioidalis in the taenia thalami of the cat and other mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208329"} {"pmid": "4208331", "title": "Capacity of group A, B, C, D, and G streptococci to agglutinate sensitized sheep red cells.", "content": "Capacity of group A, B, C, D, and G streptococci to agglutinate sensitized sheep red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208331"} {"pmid": "4208332", "title": "Association of capsid protein with Semliki Forest virus messenger RNAs.", "content": "Association of capsid protein with Semliki Forest virus messenger RNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208332"} {"pmid": "4208333", "title": "\"Pitting\" and \"corrosion\" of the surface of agar cultures by colonies of some bacteria from the respiratory tract.", "content": "\"Pitting\" and \"corrosion\" of the surface of agar cultures by colonies of some bacteria from the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208333"} {"pmid": "4208334", "title": "Search for thymidine phosphorylase, nucleoside deoxyribosyltransferase and thymidine kinase in genus Neisseria.", "content": "Search for thymidine phosphorylase, nucleoside deoxyribosyltransferase and thymidine kinase in genus Neisseria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208334"} {"pmid": "4208335", "title": "Bacteriophage typing of Mycobacterium ranae (Fortuitum). The use of unadapted and adapted phages in the development of a typing system.", "content": "Bacteriophage typing of Mycobacterium ranae (Fortuitum). The use of unadapted and adapted phages in the development of a typing system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208335"} {"pmid": "4208337", "title": "Patient compliance with antibiotic regimens.", "content": "Patient compliance with antibiotic regimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208337"} {"pmid": "4208336", "title": "Encephalogenic cardiomyopathy after stimulation of the brain stem in monkeys.", "content": "Encephalogenic cardiomyopathy after stimulation of the brain stem in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208336"} {"pmid": "4208338", "title": "Problems of treatment of anorexia nervosa.", "content": "Problems of treatment of anorexia nervosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208338"} {"pmid": "4208339", "title": "The treatment of advanced prostatic carcinoma with medroxyprogesterone.", "content": "The treatment of advanced prostatic carcinoma with medroxyprogesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208339"} {"pmid": "4208340", "title": "A comparison of propranolol and prindolol in the treatment of essential hypertension.", "content": "A comparison of propranolol and prindolol in the treatment of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208340"} {"pmid": "4208341", "title": "Clinical evaluation of SE 1520 in the treatment of hypertension.", "content": "Clinical evaluation of SE 1520 in the treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208341"} {"pmid": "4208342", "title": "A double-blind comparison of two oral contraceptives containing 50 mu g. and 30 mu g. ethinyl estradiol.", "content": "A double-blind comparison of two oral contraceptives containing 50 mu g. and 30 mu g. ethinyl estradiol. 150 women participated in a double-blind clinical trial comparing 2 dosages of an oral contraceptive agent: 250 mcg d-norgestrel + 50 mcg ethinyl estradiol and 150 mcg d-norgestrel + 30 mcg ethinyl estradiol. The 150/30 combination resulted in shorter cycles, longer menses (p.001), shorter latent period (p.001), and a higher instance of breakthrough bleeding and spotting (p.05 and p.001). The 250/50 dose caused a significantly higher incidence of breast discomfort (p.001), leg cramps (.02), and nausea (.001). More 250/50 dose women dropped out for more than 1 reason than in the lower dose group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208342"} {"pmid": "4208343", "title": "A double-blind clinical evaluation of the safety and efficacy of phentermine hydrochloride (Fastin) in the treatment of exogenous obesity.", "content": "A double-blind clinical evaluation of the safety and efficacy of phentermine hydrochloride (Fastin) in the treatment of exogenous obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208343"} {"pmid": "4208344", "title": "Doxycycline treatment in gonorrhea.", "content": "Doxycycline treatment in gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208344"} {"pmid": "4208345", "title": "The rapidity of the effect of different types of topical corticosteroids: a double-blind comparison between Diproderm ointment 0.05 percent and Calmuril-Hydrocortisone 1 percent.", "content": "The rapidity of the effect of different types of topical corticosteroids: a double-blind comparison between Diproderm ointment 0.05 percent and Calmuril-Hydrocortisone 1 percent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208345"} {"pmid": "4208346", "title": "Osteomyelitis associated with vascular insufficiency.", "content": "Osteomyelitis associated with vascular insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208346"} {"pmid": "4208347", "title": "Clinical observations on the use of a long-acting phenothiazine (fluphenazine enanthate) in chronic schizophrenics.", "content": "Clinical observations on the use of a long-acting phenothiazine (fluphenazine enanthate) in chronic schizophrenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208347"} {"pmid": "4208348", "title": "The use of mesoridazine in geriatrics.", "content": "The use of mesoridazine in geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208348"} {"pmid": "4208349", "title": "Structure-activity relationships within the class of 1,4-benzodiazepines: presence of chlorine and central nervous system activities.", "content": "Structure-activity relationships within the class of 1,4-benzodiazepines: presence of chlorine and central nervous system activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208349"} {"pmid": "4208350", "title": "Bioavailability and activity of betamethasone 17-benzoate in gel and cream formulations: comparison with proprietary topical corticosteroid preparations in the vasoconstrictor assay.", "content": "Bioavailability and activity of betamethasone 17-benzoate in gel and cream formulations: comparison with proprietary topical corticosteroid preparations in the vasoconstrictor assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208350"} {"pmid": "4208351", "title": "Characteristic actions of CDP-choline on the central nervous system.", "content": "Characteristic actions of CDP-choline on the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208351"} {"pmid": "4208352", "title": "A comparison of three laboratory tests for pregnancy diagnosis in the mare.", "content": "A comparison of three laboratory tests for pregnancy diagnosis in the mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208352"} {"pmid": "4208353", "title": "The neutral proteases of human granulocytes. Isolation and partial characterization of granulocyte elastases.", "content": "The neutral proteases of human granulocytes. Isolation and partial characterization of granulocyte elastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208353"} {"pmid": "4208354", "title": "Secondary isotope effect in the phosphorylase reaction.", "content": "Secondary isotope effect in the phosphorylase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208354"} {"pmid": "4208355", "title": "Purification and some properties of an endocellular sucrase from a constitutive mutant of Bacillus subtilis Marburg 168.", "content": "Purification and some properties of an endocellular sucrase from a constitutive mutant of Bacillus subtilis Marburg 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208355"} {"pmid": "4208356", "title": "Fluorescent products from aging Drosophila melanogaster: an indicator of free radical lipid peroxidation damage.", "content": "Fluorescent products from aging Drosophila melanogaster: an indicator of free radical lipid peroxidation damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208356"} {"pmid": "4208357", "title": "Are there major degenerative changes in the flight muscle of ageing diptera?", "content": "Are there major degenerative changes in the flight muscle of ageing diptera?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208357"} {"pmid": "4208362", "title": "Perfusion fixation of the kidney of the domestic fowl.", "content": "Perfusion fixation of the kidney of the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208362"} {"pmid": "4208363", "title": "Cellular distribution of beta-trace protein in CNS and brain tumours.", "content": "Cellular distribution of beta-trace protein in CNS and brain tumours. The low-molecular weight beta-trace protein constitutes about seven per cent of the total protein content in human cerebrospinal fluid. Within the central nervous system the protein is found predominantly in white matter and fractions enriched in glial cells. Immunofluorescence studies on sections of monkey brains show that beta-trace protein is particularly localized to cells such as astrocytes and oligodendrocytes. Significantly higher amounts of beta-trace protein are found in brain tumours derived from glial cells than in other tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208363"} {"pmid": "4208360", "title": "Orally administered betahistine and regional cerebral blood flow in cerebrovascular disease.", "content": "Orally administered betahistine and regional cerebral blood flow in cerebrovascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208360"} {"pmid": "4208369", "title": "Combined intrathecal and intramuscular gentamicin for gram-negative meningitis. Pharmacologic study of 21 patients.", "content": "Combined intrathecal and intramuscular gentamicin for gram-negative meningitis. Pharmacologic study of 21 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208369"} {"pmid": "4208370", "title": "Acquired phagocyte dysfunction. A complication of the hypophosphatemia of parenteral hyperalimentation.", "content": "Acquired phagocyte dysfunction. A complication of the hypophosphatemia of parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208370"} {"pmid": "4208371", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208371"} {"pmid": "4208361", "title": "Inhibition of clofibrate-induced antidiuresis by glybenclamide in patients with pituitary diabetes insipidus.", "content": "Inhibition of clofibrate-induced antidiuresis by glybenclamide in patients with pituitary diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208361"} {"pmid": "4208372", "title": "Editorial: Hypoalimentation during hyperalimentation.", "content": "Editorial: Hypoalimentation during hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208372"} {"pmid": "4208374", "title": "Letter: Contamination of fluid for parenteral nutrition.", "content": "Letter: Contamination of fluid for parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208374"} {"pmid": "4208373", "title": "Editorial: Vasodilator therapy of myocardial infarction.", "content": "Editorial: Vasodilator therapy of myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208373"} {"pmid": "4208359", "title": "Administrative problems and solutions in screening for gonorrhea.", "content": "Administrative problems and solutions in screening for gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208359"} {"pmid": "4208375", "title": "Organochlorine residues in woodcock wings, 11 states--1970-71.", "content": "Organochlorine residues in woodcock wings, 11 states--1970-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208375"} {"pmid": "4208376", "title": "Residues of mirex and certain other chlorinated hydrocarbon insecticides in beef fat--1971.", "content": "Residues of mirex and certain other chlorinated hydrocarbon insecticides in beef fat--1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208376"} {"pmid": "4208377", "title": "Residues of PCB's and PCT's in Canadian and imported European cheeses, Canada--1972.", "content": "Residues of PCB's and PCT's in Canadian and imported European cheeses, Canada--1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208377"} {"pmid": "4208380", "title": "Long-term treatment of endogenous depression with nortriptyline with control of plasma levels.", "content": "Long-term treatment of endogenous depression with nortriptyline with control of plasma levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208380"} {"pmid": "4208381", "title": "Psychiatric inpatients in 1982: how many beds?", "content": "Psychiatric inpatients in 1982: how many beds?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208381"} {"pmid": "4208382", "title": "Medical Research Council Unit on the Development and Integration of Behaviour.", "content": "Medical Research Council Unit on the Development and Integration of Behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208382"} {"pmid": "4208383", "title": "Inter-laboratory discrepancies in serum immunoglobulin estimations.", "content": "Inter-laboratory discrepancies in serum immunoglobulin estimations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208383"} {"pmid": "4208384", "title": "The natural history of bacterial colonization of the newborn in a maternity hospital. I.", "content": "The natural history of bacterial colonization of the newborn in a maternity hospital. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208384"} {"pmid": "4208378", "title": "Methamphetamine effects on responding under a multiple schedule of shock presentation.", "content": "Methamphetamine effects on responding under a multiple schedule of shock presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208378"} {"pmid": "4208385", "title": "Editorial: Oral therapy in diabetes mellitus.", "content": "Editorial: Oral therapy in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208385"} {"pmid": "4208386", "title": "Bilateral symmetrical periarticular trauma in epileptics.", "content": "Bilateral symmetrical periarticular trauma in epileptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208386"} {"pmid": "4208387", "title": "Failure of chemotherapy in treatment of giant condyloma acuminata (Buschke-Loewenstein tumor).", "content": "Failure of chemotherapy in treatment of giant condyloma acuminata (Buschke-Loewenstein tumor).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208387"} {"pmid": "4208388", "title": "Factor VIII, a series of homologous oligomers and a complex of two proteins.", "content": "Factor VIII, a series of homologous oligomers and a complex of two proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208388"} {"pmid": "4208379", "title": "Suppression of cocaine self-administration by extinction and punishment.", "content": "Suppression of cocaine self-administration by extinction and punishment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208379"} {"pmid": "4208389", "title": "Shwartzman reaction in an HL-A-identical renal allograft.", "content": "Shwartzman reaction in an HL-A-identical renal allograft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208389"} {"pmid": "4208396", "title": "Chronogenetics. Its foundations, scope, and impact.", "content": "Chronogenetics. Its foundations, scope, and impact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208396"} {"pmid": "4208398", "title": "Tympanoplasty for bony ossicular fixation.", "content": "Tympanoplasty for bony ossicular fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208398"} {"pmid": "4208399", "title": "Staphylococcal endocarditis following septorhinoplasty.", "content": "Staphylococcal endocarditis following septorhinoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208399"} {"pmid": "4208400", "title": "Letter: Gold nephropathy and glucocorticoids.", "content": "Letter: Gold nephropathy and glucocorticoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208400"} {"pmid": "4208401", "title": "Immunological enhancement of atherogenesis in rabbits. Persistent susceptibility to atherogenic diet following experimentally induced serum sickness.", "content": "Immunological enhancement of atherogenesis in rabbits. Persistent susceptibility to atherogenic diet following experimentally induced serum sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208401"} {"pmid": "4208402", "title": "Alveolar macrophage function in immunized, burned rats.", "content": "Alveolar macrophage function in immunized, burned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208402"} {"pmid": "4208403", "title": "A comparative study of the distribution of soluble and particulate glycyl-L-leucine hydrolase in the small intestine.", "content": "A comparative study of the distribution of soluble and particulate glycyl-L-leucine hydrolase in the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208403"} {"pmid": "4208404", "title": "Increased glucuronidation of bilirubin in man and rat by administration of antipyrine (phenazone).", "content": "Increased glucuronidation of bilirubin in man and rat by administration of antipyrine (phenazone).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208404"} {"pmid": "4208406", "title": "The ventilatory response in diabetic ketoacidosis.", "content": "The ventilatory response in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208406"} {"pmid": "4208405", "title": "Effect of nicotinic acid on cholesterol metabolism in monkeys.", "content": "Effect of nicotinic acid on cholesterol metabolism in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208405"} {"pmid": "4208407", "title": "Hypothalamic control of anterior pituitary hormone secretion--characterized hypothalamic-hypophysiotropic peptides.", "content": "Hypothalamic control of anterior pituitary hormone secretion--characterized hypothalamic-hypophysiotropic peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208407"} {"pmid": "4208408", "title": "Establishment of multiple lymphoblastoid lines from single lymph nodes and study of their immunoglobulin synthesis.", "content": "Establishment of multiple lymphoblastoid lines from single lymph nodes and study of their immunoglobulin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208408"} {"pmid": "4208409", "title": "The underdevelopment of health or the health of underdevelopment: an analysis of the distribution of human health resources in Latin America.", "content": "The underdevelopment of health or the health of underdevelopment: an analysis of the distribution of human health resources in Latin America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208409"} {"pmid": "4208397", "title": "Experimental middle ear effusions: an immunofluorescent study.", "content": "Experimental middle ear effusions: an immunofluorescent study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208397"} {"pmid": "4208410", "title": "Percent charging of transfer ribonucleic acid and levels of ppGpp and pppGpp in dormant and germinated spores of Bacillus megaterium.", "content": "Percent charging of transfer ribonucleic acid and levels of ppGpp and pppGpp in dormant and germinated spores of Bacillus megaterium. The levels of transfer ribonucleic acids (tRNAs) specific for 14 amino acids were almost identical in dormant spores and in spores germinated from 6 to 75 min. Germinated spore tRNAs specific for all amino acids tested were between 63 and 93% charged, and there was no significant change in this value from 6 to 75 min of germination. In contrast, tRNAs isolated from dormant spores specific for nine different amino acids were almost completely(>93%) uncharged. However, some dormant spore tRNAs, i.e., those for arginine, histidine, isoleucine, and valine, showed significant (21 to 72%) levels of aminoacylation. Dormant spores contained no detectable guanosine penta- (pppGpp), tetra- (ppGpp), or triphosphate (GTP). However, these nucleotides appeared in the first minutes of germination, and thereafter all increased in parallel with a ratio of pppGpp plus ppGpp to GTP of 0.07 to 0.11, which is characteristic of unstarved vegetative cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208410"} {"pmid": "4208411", "title": "Physiological influences on cell division patterns in the div IV-B1 MINIcell-producing mutant of Bacillus subtilis.", "content": "Physiological influences on cell division patterns in the div IV-B1 MINIcell-producing mutant of Bacillus subtilis. The proportion of abnormal divisions resulting in minicells is influenced by growth stage and medium composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208411"} {"pmid": "4208412", "title": "Acceleration of dextransucrase activity of Streptococcus mutans by secretory immunoglobulin A.", "content": "Acceleration of dextransucrase activity of Streptococcus mutans by secretory immunoglobulin A. The effect of immunoglobulins on the activity of dextransucrase purified from Streptococcus mutans strain HS-6 is described. When human salivary immunoglobulin A (IgA) or colostral IgA, either natured or denatured, was incubated with dextransucrase, the rate of the dextran synthesis was markedly accelerated, whereas human serum IgA or IgG neither accelerated nor inhibited the enzyme activity. The results suggest that a portion unique for secretory IgA, the secretory component, might be related to the enzyme acceleration. On the other hand, specific rabbit antiserum against the dextransucrase inhibited completely dextran synthesis by the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208412"} {"pmid": "4208413", "title": "Specificity and induction of undecyl acetate esterase from Pseudomonas cepacia grown on 2-tridecanone.", "content": "Specificity and induction of undecyl acetate esterase from Pseudomonas cepacia grown on 2-tridecanone. Undecyl acetate esterase from Pseudomonas cepacia grown on 2-tridecanone was strongly inhibited by organophosphates and other esterase inhibitors. Also, p-chloromercuribenzoate at 1 x 10(-4) M showed a 70% inhibition of esterase activity. The enzyme hydrolyzed both aliphatic and aromatic acetate esters at substrate concentrations of 0.25 M. Under these conditions the highest reaction rate was toward undecyl acetate. No lipase or proteolytic activity was demonstrated. Undecyl acetate esterase was classified as a carboxylesterase (B-esterase). Cell-free activity studies on the production of undecyl acetate esterase grown on different carbon sources plus zymogram studies demonstrated that the enzyme was inducible when 2-tridecanone, 2-tridecanol, undecyl acetate and, to a lesser extent, 1-undecanol were growth substrates. Induction of undecyl acetate esterase during oxidation of 2-tridecanone supports the view that undecyl acetate is an intermediate in the degradation of the methyl ketone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208413"} {"pmid": "4208414", "title": "Tests for deoxyribonucleic acid synthesis in toluenized Bacillus subtilis cells.", "content": "Tests for deoxyribonucleic acid synthesis in toluenized Bacillus subtilis cells. Several tests were devised to further characterize deoxyribonucleic acid (DNA) synthesis in toluenized Bacillus subtilis cells. Vigorous agitation of toluenized cells (localization test) demonstrated that the DNA replication is exclusively a cell-associated process. A DNA \"repair\" condition was also applied to toluenized cells and shown to be distinct from DNA replication in its DNA polymerase I dependency and its ability to synthesize DNA on template which is either cell associated or free, outside the cell. This repair condition was used in conjunction with the localization test to demonstrate the penetration of deoxyribonuclease I and possibly DNA polymerase I into toluenized cells. Therefore, we suggest that the localization test can be used to test the penetration of proteins into toluenized cells for both the DNA repair and replication processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208414"} {"pmid": "4208415", "title": "Pyruvate carboxylase deficiency in pleiotropic carbohydrate-negative mutant strains of Pseudomonas aeruginosa.", "content": "Pyruvate carboxylase deficiency in pleiotropic carbohydrate-negative mutant strains of Pseudomonas aeruginosa. Cell extracts of Pseudomonas aeruginosa strain PAO were found to contain pyruvate carboxylase activity. Specific activities were minimal when cells were grown on Casamino Acids, acetate, or succinate, but were three- to fourfold higher when cells were grown in glucose, gluconate, glycerol, lactate, or pyruvate minimal media. The reaction in crude cell extracts and in partially purified preparations was dependent on pyruvate, adenosine 5'-triphosphate, and Mg(2+), but was not affected by either the presence or absence of acetyl coenzyme A. Activity was nearly totally inhibited by avidin and this inhibition was substantially blocked by free biotin in incubation mixtures. Cell extracts were shown to fix (14)CO(2) in a reaction that had these same characteristics. Eight pleiotropic, carbohydrate-negative mutant strains of the organism were isolated after nitrosoguanidine mutagenesis. Each mutant strain grew normally in acetate, succinate, and citrate minimal media but failed to utilize glucose, gluconate, 2-ketogluconate, mannitol, glycerol, lactate, and pyruvate as sole sources of carbon and energy. These strains were found by quantitative transductional analysis with phage F116 to form a single linkage group. Cell extracts of each mutant strain were either lacking or severely deficient in pyruvate carboxylase activity. Spontaneous revertants of five of the eight strains were isolated and found to recover simultaneously both pyruvate carboxylase activity and the ability to utilize each of the C(6) and C(3) compounds. A second linkage group of similar mutant strains that grew on the C(3) compounds was found to contain normal levels of pyruvate carboxylase activity, but each strain was deficient in an enzyme of the Entner-Doudoroff pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208415"} {"pmid": "4208416", "title": "Induction of partial immunologic tolerance in rats and progressive loss of cellular antigenicity in Gross virus lymphoma.", "content": "Induction of partial immunologic tolerance in rats and progressive loss of cellular antigenicity in Gross virus lymphoma. Gross virus-induced lymphoma cells express strong virus-associated (Gross murine leukemia virus [G-MuLV]) antigens and are consistently rejected when grafted in normal adult syngeneic rats. By contrast, similar grafts are tolerated and allowed to grow progressively by rats that have been injected at birth with deaggregated G-MuLV antigens. However, the tolerance induced by this procedure is only partial as the grafted lymphoma cells lose their G-MuLV membrane antigens. These cells showing an antigenic disjunction, with negative membrane and positive cytoplasmic G-MuLV antigenic expression, become transplantable in normal-nonconditioned adult recipients. By further grafting, the expression of cytoplasmic G-MuLV antigens is similarly lost while the lymphoma cells substantially increase their transplantability, rate of growth, and capacity for metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208416"} {"pmid": "4208419", "title": "The nicotinic cholinergic receptor protein: improved purification method, preliminary amino acid composition and observed auto-immuno response.", "content": "The nicotinic cholinergic receptor protein: improved purification method, preliminary amino acid composition and observed auto-immuno response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208419"} {"pmid": "4208418", "title": "Nuclear localization of S-100 protein.", "content": "Nuclear localization of S-100 protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208418"} {"pmid": "4208417", "title": "The mediator of cellular immunity. VII. Localization of sensitized lymphocytes in inflammatory exudates.", "content": "The mediator of cellular immunity. VII. Localization of sensitized lymphocytes in inflammatory exudates. Peritoneal exudates induced in rats infected with Listeria monocytogenes contain sensitized lymphocytes which can protect normal recipients against a Listeria challenge. The protective cells arise in lymphoid tissue remote from the peritoneal cavity. Those formed in the caudal lymph nodes of subcutaneously infected rats are delivered to the thoracic duct and hence to the blood from where they are drawn into exudates. Immunoblasts are the most immature members of this protective cell population and they alone among the cells in central lymph localize in exudates induced by killed bacteria. They do so in substantial numbers, but only during the early postinduction period. The \"homing\" of immunoblasts to inflammatory foci seems to be determined by a general property of the cells rather than their immunological commitment; however, the intense inflammation induced by organisms to which an animal has been specifically sensitized is accompanied by an exuberant influx of immunoblasts into lesions. Sensitized lymphocytes that extravasate in the inflamed peritoneal may generate more of their own kind, but some give rise to small lymphocytes. The latter also have protective properties and, with time, comprise an increasing portion of the protective cell population. The results imply that the tissue disposition of sensitized lymphocytes in the body is determined by a complementary relationship between blood-borne immunoblasts and vascular endothelium in inflamed tissue. The results also provide a plausible explanation for the concentration of sensitized lymphocytes at sites of microbial implantation where they alone would be expected to collaborate with monocyte-derived macrophages in the control of infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208417"} {"pmid": "4208420", "title": "Immunological approach to the characterization of cholinergic vesicular protein.", "content": "Immunological approach to the characterization of cholinergic vesicular protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208420"} {"pmid": "4208421", "title": "Immunochemical studies on cholinergic synaptic vesicles.", "content": "Immunochemical studies on cholinergic synaptic vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208421"} {"pmid": "4208422", "title": "Electrophoretic profiles of aqueous-soluble proteins of human cerebral cortex: population and developmental characteristics.", "content": "Electrophoretic profiles of aqueous-soluble proteins of human cerebral cortex: population and developmental characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208422"} {"pmid": "4208423", "title": "Increased concentrations of acidic metabolites of dopamine in the superior cervical ganglion following preganglionic stimulation in vivo.", "content": "Increased concentrations of acidic metabolites of dopamine in the superior cervical ganglion following preganglionic stimulation in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208423"} {"pmid": "4208425", "title": "Antibacterial efficiency of mercurials.", "content": "Antibacterial efficiency of mercurials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208425"} {"pmid": "4208424", "title": "Brain sphingolipids in I cell disease (mucolipidosis II).", "content": "Brain sphingolipids in I cell disease (mucolipidosis II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208424"} {"pmid": "4208426", "title": "Intestinal motor effects of a unique analgesic agent.", "content": "Intestinal motor effects of a unique analgesic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208426"} {"pmid": "4208427", "title": "Letter: Relationship between pH and antibacterial activity of glutaraldehyde.", "content": "Letter: Relationship between pH and antibacterial activity of glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208427"} {"pmid": "4208428", "title": "Intracellular J chain in mouse plasmacytomas secreting IgA, IgM and IgG.", "content": "Intracellular J chain in mouse plasmacytomas secreting IgA, IgM and IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208428"} {"pmid": "4208430", "title": "Complement-mediated mixed aggregation of murine spleen cells.", "content": "Complement-mediated mixed aggregation of murine spleen cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208430"} {"pmid": "4208429", "title": "Lipopolysaccharides inhibit lymphosarcoma cells of bone marrow orgin.", "content": "Lipopolysaccharides inhibit lymphosarcoma cells of bone marrow orgin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208429"} {"pmid": "4208431", "title": "Bacteroids in the ovaries of a tsetse fly.", "content": "Bacteroids in the ovaries of a tsetse fly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208431"} {"pmid": "4208432", "title": "Infectious particles in a marine ciliate.", "content": "Infectious particles in a marine ciliate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208432"} {"pmid": "4208433", "title": "Deposition of DDE and polychlorinated biphenyls in dated sediments of the Santa Barbara basin.", "content": "Deposition of DDE and polychlorinated biphenyls in dated sediments of the Santa Barbara basin. Analysis of dated oceanic sediments from the Santa Barbara Basin of the Southern California Bight has shown that deposition of polychlorinated biphenyls (PCB) began about 1945 and that DDE [1,1-dichloro-2-2-bis(p-chloro-phenyl)ethylene] first appeared in sediments deposited about 1952. Concentrations of both show a progressive increase through 1967; estimated deposition rates (in grams per square meter per year) in 1967 of DDE and PCB were 1.9 x 10(-4) and 1.2 x 10(-4), respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208433"} {"pmid": "4208440", "title": "Addison's disease--serological studies.", "content": "Addison's disease--serological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208440"} {"pmid": "4208441", "title": "The effect of thyrotrophin releasing hormone on the release of thyrotrophin and other pituitary hormones in man under basal conditions and following adrenergic blocking agents.", "content": "The effect of thyrotrophin releasing hormone on the release of thyrotrophin and other pituitary hormones in man under basal conditions and following adrenergic blocking agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208441"} {"pmid": "4208443", "title": "Thyrotrophin releasing factor (TRF) in cerebrospinal fluid of the 3rd ventricle of rat.", "content": "Thyrotrophin releasing factor (TRF) in cerebrospinal fluid of the 3rd ventricle of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208443"} {"pmid": "4208442", "title": "Iodoproteins in congenital goitre with elevated levels of serum TSH and T3.", "content": "Iodoproteins in congenital goitre with elevated levels of serum TSH and T3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208442"} {"pmid": "4208444", "title": "Para-articular ossifications after total hip replacement.", "content": "Para-articular ossifications after total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208444"} {"pmid": "4208446", "title": "Inborn errors of lipid metabolism.", "content": "Inborn errors of lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208446"} {"pmid": "4208445", "title": "On the transferrin concentration in serum of sows and growing pigs and in sow colostrum.", "content": "On the transferrin concentration in serum of sows and growing pigs and in sow colostrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208445"} {"pmid": "4208447", "title": "Liver injury in protein-calorie malnutrition: an electron microscopic study.", "content": "Liver injury in protein-calorie malnutrition: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208447"} {"pmid": "4208448", "title": "Stature and lean body mass.", "content": "Stature and lean body mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208448"} {"pmid": "4208449", "title": "Impaired cellular immunity in marasmic infants.", "content": "Impaired cellular immunity in marasmic infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208449"} {"pmid": "4208450", "title": "Serum levels of immunoglobulins, cell-mediated immunity, and phagocytosis in protein-calorie malnutrition.", "content": "Serum levels of immunoglobulins, cell-mediated immunity, and phagocytosis in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208450"} {"pmid": "4208451", "title": "Some effects of malnutrition on the immune response in man.", "content": "Some effects of malnutrition on the immune response in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208451"} {"pmid": "4208452", "title": "Effects of protein insufficiency on immune responsiveness.", "content": "Effects of protein insufficiency on immune responsiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208452"} {"pmid": "4208454", "title": "Something old, something new in the visual act of the patient with strabismus.", "content": "Something old, something new in the visual act of the patient with strabismus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208454"} {"pmid": "4208453", "title": "An evaluation of factors associated with the depression of immunity in malnutrition and in measles.", "content": "An evaluation of factors associated with the depression of immunity in malnutrition and in measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208453"} {"pmid": "4208455", "title": "Bacterial microflora of the upper gastrointestinal tract in infants without diarrhoea.", "content": "Bacterial microflora of the upper gastrointestinal tract in infants without diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208455"} {"pmid": "4208456", "title": "Iodine balance studies in protein-calorie malnutrition.", "content": "Iodine balance studies in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208456"} {"pmid": "4208458", "title": "On the increased precursor incorporation into the DNA of rat liver mitochondria irradiated in vitro.", "content": "On the increased precursor incorporation into the DNA of rat liver mitochondria irradiated in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208458"} {"pmid": "4208459", "title": "The use of immunoadsorbent columns for the isolation of antibodies specific for antigens associated with human bronchogenic carcinoma.", "content": "The use of immunoadsorbent columns for the isolation of antibodies specific for antigens associated with human bronchogenic carcinoma. An immunoadsorbent technique is described whereby tumour-specific antibodies may be isolated. Extracts from normal human lung tissue were pooled and bound to cyanogen bromide activated Sepharose 4B. Antisera raised in rabbits to a variety of extracts from human bronchogenic carcinoma were passed through these immunoadsorbent columns to yield antisera specific for tumour-associated antigens as demonstrated by immunodiffusion and immunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208459"} {"pmid": "4208461", "title": "Reinterpretation of hyperamylasemia in diabetic coma.", "content": "Reinterpretation of hyperamylasemia in diabetic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208461"} {"pmid": "4208462", "title": "Immunochemical measurement of lipoprotein-X.", "content": "Immunochemical measurement of lipoprotein-X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208462"} {"pmid": "4208464", "title": "Effects of hypoglycemic sulfonamides on glucagon and insulin secretion in ducks and dogs.", "content": "Effects of hypoglycemic sulfonamides on glucagon and insulin secretion in ducks and dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208464"} {"pmid": "4208463", "title": "Metabolic effects of sodium bicarbonate in management of diabetic ketoacidosis.", "content": "Metabolic effects of sodium bicarbonate in management of diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208463"} {"pmid": "4208465", "title": "Metabolism of trehalose in Euglena gracilis. Beta glucose 1,6-bisphosphate, activation factor of phosphoglucomutase for beta glucose 1-phosphate.", "content": "Metabolism of trehalose in Euglena gracilis. Beta glucose 1,6-bisphosphate, activation factor of phosphoglucomutase for beta glucose 1-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208465"} {"pmid": "4208467", "title": "If all the sea were PCB.", "content": "If all the sea were PCB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208467"} {"pmid": "4208468", "title": "Effects of anti-human neutrophil antibodies in vitro. Quantitative studies.", "content": "Effects of anti-human neutrophil antibodies in vitro. Quantitative studies. Opsonic, antiphagocytic, cytotoxic, and metabolic effects of homologous and heterologous antibodies against human neutrophils were analyzed by means of quantitative assays to facilitate detection of antibody activity, and to probe membrane function of these cells. Normal human neutrophils were purified by gradient centrifugation, sensitized with heat-inactivated antineutrophil antisera, and incubated with rabbit alveolar macrophages in balanced salt solution containing nitroblue tetrazolium. The macrophages engulfed sensitized neutrophils and reduced nitroblue tetrazolium to formazan in phagocytic vacuoles. The initial rate of nitroblue tetrazolium reduction by macrophages ingesting the neutrophils was measured spectrophotometrically. Neutrophils treated with rabbit anti-human leukocyte antiserum or IgG, with sera from mothers of infants with neonatal isoimmune neutropenia, and with 27% of sera from frequently transfused patients promoted rapid rates of nitroblue tetrazolium reduction by alveolar macrophages. This indicates that antineutrophil antibodies without added complement opsonized neutrophils for ingestion by the macrophages. Some sera from frequently transfused patients with opsonic activity for certain donors' neutrophils did not agglutinate these neutrophils (44%), did not lyse them in the presence of fresh plasma (47%), and did not inhibit phagocytosis of particles by the neutrophils (26%). The reverse was not observed. The opsonic activity of antineutrophil antiserum appears to be the most sensitive and a quantitative means of detecting antibody activity in vitro.Low concentrations of rabbit anti-human leukocyte antisera or IgG stimulated the ingestion rate of unopsonized or opsonized particles by human neutrophils, and, as previously reported by others, enhanced rates of oxidation of [1-(14)C]glucose by the cells. High concentrations of the antisera or IgG inhibited ingestion. All concentrations of homologous antineutrophil antisera tested only inhibited ingestion of particles by neutrophils and none altered rates of resting glucose oxidation by the cells. The findings suggest that heterologous antibodies disturb membrane antigens that trigger oxidative metabolism and enhance as well as inhibit ingestion, and that these antigens are common to all human neutrophils. In contrast to other studies with antimacrophage antibodies, antineutrophil antibodies altered phagocytic rates of both unopsonized and opsonized particles although there were differences in dose-response curves depending on the type of particle tested. Thus, antineutrophil antibodies do not merely cover selected receptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208468"} {"pmid": "4208469", "title": "The effects of the natriuretic factor from uremic urine on sodium transport, water and electrolyte content, and pyruvate oxidation by the isolated toad bladder.", "content": "The effects of the natriuretic factor from uremic urine on sodium transport, water and electrolyte content, and pyruvate oxidation by the isolated toad bladder. The urine of patients with chronic uremia contains a gel filtration fraction that is natriuretic in the rat. The effects of this fraction on the isolated urinary bladder of the toad were examined in the present studies. When added to the serosal surface of the bladder, a significant and substantial fall in short-circuit current and potential difference was observed. The changes began after a lag period of at least 10 min and continued over a period of 60 min. The decrease in short-circuit current at the end of 1 h averaged 44%. The same fraction from the urine of normal subjects produced no significant change in either short-circuit current or potential difference. When the isolated epithelial cells from the toad bladder were incubated in the presence of the inhibitor, intracellular sodium content increased significantly. There was no change in intracellular water content; hence the intracellular concentration of sodium increased by a mean of 7 meq/liter. The changes in intracellular potassium content and concentration were not satistically significant. When the isolated epithelia were incubated with the uremic factor, there was also a significant decrease in pyruvate utilization in relation to cells from paired hemibladders incubated in the absence of the fraction. The fraction from normal subjects produced no change in either intracellular sodium content or pyruvate oxidation. The results suggest that the inhibitor acts from the serosal surface, inhibits sodium transport across the serosal barrier, and produces a decrease in substrate utilization in association with the change in transepithelial sodium transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208469"} {"pmid": "4208471", "title": "The mechanism of uridine diphosphate-sugar-4-epimerase reactions. Isotope discrimination with 4-tritiated substrates.", "content": "The mechanism of uridine diphosphate-sugar-4-epimerase reactions. Isotope discrimination with 4-tritiated substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208471"} {"pmid": "4208470", "title": "Hypothalamic-pituitary function in diverse hyperprolactinemic states.", "content": "Hypothalamic-pituitary function in diverse hyperprolactinemic states. Prolactin secretion in normal adults is characterized by periods of episodic secretion which increase in magnitude during sleep. In this study, we report the 24-h mean prolactin concentrations, prolactin secretory patterns, and associated pituitary hormone function in nine patients (seven women and two men) with hyperprolactinemia of diverse etiologies. Four of the women and one of the men had clinically demonstrable pituitary tumors, one boy had a hypothalamic tumor, and the three other women had \"functional\" hyperprolactinemia. The 24-h mean prolactin concentrations derived from averaging the 20-min interval samples for 24 h ranged from 28.6 to 1,220 ng/ml. The plasma prolactin patterns in these patients showed persistence of episodic secretion in all and loss of the normal sleep-wake difference in plasma prolactin in seven of nine. Three of the patients with galactorrhea and comparable 24-h mean prolactin concentrations (58.3, 59.7, and 64.3 ng/ml) showed similar prolactin secretory patterns despite different etiologic mechanisms. Evaluation of the secretory patterns of luteinizing hormone (LH) in these patients showed loss of normal pulsatile LH release and a low 24-h mean LH concentration in the patient with the pituitary tumor, while the two patients without clinically demonstrable pituitary tumors (\"post-pill\" galactorrhea and \"idiopathic\" galactorrhea) showed normal LH secretory patterns and 24-h mean LH concentrations. The 24-h mean cortisol concentrations and secretory patterns were normal in five of the seven patients who had these parameters measured. The patient with the hypothalamic tumor had a low 24-h mean cortisol concentration and production rate and absent response to metyrapone. The patient with \"idiopathic\" galactorrhea had an elevated 24-h mean cortisol concentration but normal cortisol production rate and urinary 17-hydroxycorticoid excretion. Growth hormone secretion was abnormal in four of the patients (one with the hypothalamic tumor and three with pituitary tumors). Thyrotropin-releasing hormone (TRH) administration in four patients resulted in normal TSH release in two patients (one of whom developed galactorrhea after the test), an absent response in the patient with the hypothalamic tumor, and a blunted response in one of the women with a pituitary tumor. The two men had low 24-h mean plasma testosterone concentrations (69 and 30 ng/100 ml) and symptoms of impotence and loss of libido. Five of the women (four with pituitary tumors and one with Chiari-Frommel syndrome) had either low 24-h mean LH concentrations, abnormal LH secretory patterns, or both. These data indicate that patients with hyperprolactinemia encompassing a varied etiological range frequently show loss of the normal sleep-associated increase in prolactin secretion as well as abnormalities in the regulation of the other hypothalamic pituitary-regulated hormones. The finding that the abnormalities in LH, growth hormone, thyrotropin, and cortisol (adrenocorticotrophic) secretion were almost uniformly confined to the patients with the clinically demonstrable hypothalamic or pituitary tumors suggests that the size of the lesion is the critical factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208470"} {"pmid": "4208472", "title": "Deoxyribonucleic acid polymerase from Tetrahymena pyriformis. Purification and properties of the major activity in exponentially growing cells.", "content": "Deoxyribonucleic acid polymerase from Tetrahymena pyriformis. Purification and properties of the major activity in exponentially growing cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208472"} {"pmid": "4208473", "title": "On the specificity of phospho-N-acetylmuramyl-pentapeptide translocase. The peptide subunit of uridine diphosphate-N-actylmuramyl-pentapeptide.", "content": "On the specificity of phospho-N-acetylmuramyl-pentapeptide translocase. The peptide subunit of uridine diphosphate-N-actylmuramyl-pentapeptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208473"} {"pmid": "4208474", "title": "A proteolytically activated tyrosinase from frog epidermis.", "content": "A proteolytically activated tyrosinase from frog epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208474"} {"pmid": "4208477", "title": "How to handle secondary impression trays.", "content": "How to handle secondary impression trays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208477"} {"pmid": "4208476", "title": "Subunit I of G beta replicase and 30 S ribosomal protein S1 of Escherichia coli. Evidence for the identity of the two proteins.", "content": "Subunit I of G beta replicase and 30 S ribosomal protein S1 of Escherichia coli. Evidence for the identity of the two proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208476"} {"pmid": "4208475", "title": "Cytoplasmic type 80 S ribosomes associated with yeast mitochondria. 3. Changes in the amount of bound ribosomes in response to changes in metabolic state.", "content": "Cytoplasmic type 80 S ribosomes associated with yeast mitochondria. 3. Changes in the amount of bound ribosomes in response to changes in metabolic state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208475"} {"pmid": "4208478", "title": "Analysis of lung culture of Rickettsia prowazedi E strain with regard to its capacity of increasing virulence in passages on the lungs of white mice.", "content": "Analysis of lung culture of Rickettsia prowazedi E strain with regard to its capacity of increasing virulence in passages on the lungs of white mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208478"} {"pmid": "4208479", "title": "The longterm care of the patient suffering from cerebral palsy. II.", "content": "The longterm care of the patient suffering from cerebral palsy. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208479"} {"pmid": "4208480", "title": "Synthesis and antifolate activity of 10-deazaminopterin.", "content": "Synthesis and antifolate activity of 10-deazaminopterin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208480"} {"pmid": "4208481", "title": "Synthesis of 1-deaza-N10-methylfolic acid and related compounds.", "content": "Synthesis of 1-deaza-N10-methylfolic acid and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208481"} {"pmid": "4208482", "title": "Ethambutol. Synthesis of an unsaturated analog.", "content": "Ethambutol. Synthesis of an unsaturated analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208482"} {"pmid": "4208483", "title": "The induction of tumour immunity in mice using glutaraldehyde-treated tumor cells.", "content": "The induction of tumour immunity in mice using glutaraldehyde-treated tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208483"} {"pmid": "4208484", "title": "Immunological detection of antigen(s) associated with rat colon carcinoma.", "content": "Immunological detection of antigen(s) associated with rat colon carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208484"} {"pmid": "4208485", "title": "Riboflavin and adrenal cortex.", "content": "Riboflavin and adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208485"} {"pmid": "4208486", "title": "The yellow baby.", "content": "The yellow baby.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208486"} {"pmid": "4208487", "title": "Present status of radium.", "content": "Present status of radium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208487"} {"pmid": "4208489", "title": "Pulp structure in bilateral and opposing pairs of teeth.", "content": "Pulp structure in bilateral and opposing pairs of teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208489"} {"pmid": "4208490", "title": "Biologic tests of a methyl methacrylate composite material.", "content": "Biologic tests of a methyl methacrylate composite material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208490"} {"pmid": "4208491", "title": "Selective destruction of the pigmented epithelium in the ciliary body of the eye.", "content": "Selective destruction of the pigmented epithelium in the ciliary body of the eye. Perfusion of the internal carotid artery with hypertonic solution selectively destroys most of the pigmented epithelium of the ciliary body of the monkey eye, converts fenestrated endothelium of capillaries to continuous endothelium, and transiently breaks down the blood-aqueous barrier. The nonpigmented epithelium regenerates and the intraocular pressure returns to normal even though the pigmented epithelium is permanently destroyed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208491"} {"pmid": "4208502", "title": "Effect of TRH, and short-term exposure to experimental stress or cold on the serum immunoassayable TSH concentration in the rat.", "content": "Effect of TRH, and short-term exposure to experimental stress or cold on the serum immunoassayable TSH concentration in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208502"} {"pmid": "4208503", "title": "In vitro procedure for measuring phagocytosis of blood neutrophils.", "content": "In vitro procedure for measuring phagocytosis of blood neutrophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208503"} {"pmid": "4208504", "title": "Brucella ovis as a cause of abortion in ewes.", "content": "Brucella ovis as a cause of abortion in ewes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208504"} {"pmid": "4208505", "title": "Diagnosis of Mycobacterium bovis and Mycobacterium paratuberculosis infections in cattle by in vitro lymphocyte immunostimulation.", "content": "Diagnosis of Mycobacterium bovis and Mycobacterium paratuberculosis infections in cattle by in vitro lymphocyte immunostimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208505"} {"pmid": "4208506", "title": "Comparative in vitro activity of three aminoglycosidic antibiotics: BB-K8, kanamycin, and gentamicin.", "content": "Comparative in vitro activity of three aminoglycosidic antibiotics: BB-K8, kanamycin, and gentamicin. Kanamycin, BB-K8, and gentamicin were tested in parallel against 1,037 bacterial strains isolated from clinical material. The activity of BB-K8 at 20 mug/ml was comparable to that of gentamicin at 8 mug/ml against Pseudomonas aeruginosa and against Enterobacteriaceae, with the exception of gentamicin-resistant strains of Proteus rettgeri and Providencia stuartii, in which case the activities of BB-K8 and kanamycin were the same. BB-K8 exhibited little or no activity against streptococci. The activity of BB-K8 was affected by pH and inoculum size. A regression graph for inhibition data with a 10-mug disk of BB-K8 was developed, and synergistic activity of penicillin and BB-K8 against Streptococcus faecalis was tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208506"} {"pmid": "4208507", "title": "Antiprotozoal activity of rubratoxin B.", "content": "Antiprotozoal activity of rubratoxin B. Growth of Tetrahymena pyriformis HSM was inhibited by a concentration of 25 mug of rubratoxin B per ml of growth medium. The inhibitory effect of aflatoxin B(1)-rubratoxin B mixtures on growth of T. pyriformis was induced by rubratoxin B only. Total cellular deoxyribonucleic acid increased in the presence of 5 mug of rubratoxin B per ml of growth medium, whereas higher concentrations (25 mug/ml of growth medium) were required before a decrease in total protein was observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208507"} {"pmid": "4208508", "title": "Enumeration of tubercle bacilli in sputum of patients with pulmonary tuberculosis.", "content": "Enumeration of tubercle bacilli in sputum of patients with pulmonary tuberculosis. A method for precise microscopic enumeration of acid-fast bacilli in the sputum of patients with pulmonary tuberculosis is described. The total number of acid-fast bacilli and the number of culturable cell units of tubercle bacilli per milliliter of sputum were determined in 269 specimens from 28 patients collected prior to and/or during chemotherapy, to establish the usefulness of the procedure for evaluation of the effects of chemotherapy. Prior to or very early in the course of therapy, there was good agreement between microscopically and culturally measurable bacilli in 27 of 28 patients. Thereafter, there were systematic divergences in five patients and occasional divergences in most others. Yet, in general, in 20 of the 28 patients, the microscopically determined population provided a useful measure of the number of culturable tubercle bacilli present. Although the microscopic procedure does not allow species identification of mycobacteria or differentiation between viable and nonviable cells, it often provided, within hours rather than days or weeks, useful information on the residual burden of acid-fast bacilli in sputum during chemotherapy. The nature of the disease in those patients in whom microscopy failed to provide useful information is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208508"} {"pmid": "4208509", "title": "Inactivation of dried bacteria and bacterial spores by means of gamma irradiation at high temperatures.", "content": "Inactivation of dried bacteria and bacterial spores by means of gamma irradiation at high temperatures. Dried preparations with Streptococcus faecium, strain A(2)1, and spores of Bacillus sphaericus, strain C(I)A, normally used for control of the microbiological efficiency of radiation sterilization plants and preparations with spores of Bacillus subtilis, normally used for control of sterilization by dry heat, formalin, and ethylene oxide, as well as similar preparations with Micrococcus radiodurans, strain R(1), and spores of Bacillus globigii (B. subtilis, var. niger) were gamma irradiated with dose rates from 16 to 70 krad/h at temperatures from 60 to 100 C. At 80 C the radiation response of the spore preparations was the same as at room temperature, whereas the radiation resistance of the preparations with the two vegetative strains was reduced. At 100 C the radiation response of preparations with spores of B. subtilis was unaffected by the high temperature, whereas at 16 and and 25 krad/h the radiation resistance of the radiation-resistant sporeformer B. sphaericus, strain C(I)A, was reduced to the level of radiation resistance of preparations with spores of B. subtilis. It is concluded that combinations of heat and gamma irradiation at the temperatures and dose rates tested may have very few practical applications in sterilization of medical equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208509"} {"pmid": "4208510", "title": "Effect of heat on the antimicrobial activity of brillant green dye.", "content": "Effect of heat on the antimicrobial activity of brillant green dye. Antimicrobial activity of brilliant green dye in Trypticase soy broth (BBL) is reduced and ultimately destroyed by prolonged autoclaving at 121 C. Loss of antimicrobial activity is accompanied by decolorization of the dye. This is consistent with other evidence that antimicrobial activity of brilliant green resides in the colored dye ion. The dye is not decolorized when heated in distilled water or peptone, but is decolorized by heating in glucose, glycine, or sodium dodecyl sulfate, showing that decolorization results from reaction with components of the medium. To ensure optimal results, it is recommended that bacteriological media be sterilized by heat prior to addition of brilliant green dye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208510"} {"pmid": "4208511", "title": "Salmonellae in the environment around a chicken processing plant.", "content": "Salmonellae in the environment around a chicken processing plant. Studies have been conducted over a 2-year period to determine the extent to which a poultry processing plant served as a reservoir of salmonellae reaching the external environment, to examine the question of the importance of salmonellae in the environment, and to consider how best to control the spread of the organisms. The studies have been undertaken at a chicken processing plant handling between 75,000 and 80,000 birds per day. Populations of salmonellae and indicator bacteria were estimated in the raw wastes, through the waste treatment plant, and in the receiving stream waters. The results demonstrate that salmonellae are present in poultry processing wastes in a surprisingly constant relation to fecal coliforms (in excess of 1 Salmonella per 500 fecal coliforms), that serotypes in the environment are constantly changing, and that they may reflect unusual conditions in the processing plant, or a possible source of infection among human and animal residents of the environment. Disinfection of poultry processing wastes is recommended.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208511"} {"pmid": "4208512", "title": "Immobilized aspartase-containing microbial cells: preparation and enzymatic properties.", "content": "Immobilized aspartase-containing microbial cells: preparation and enzymatic properties. The immobilization of asparatase-containing Escherichia coli was investigated by various methods, and the most active immobilized cells were obtained by entrapment in a polyacrylamide gel lattice. Other asparatase-containing bacteria were also entrapped by the same method, and the enzymatically active immobilized cells were obtained. The aspartase activity of the immobilized E. coli cells was increased nine- to tenfold by autolysis of the cells entrapped in the gel lattice. Enzymatic properties of the immobilized E. coli cells were investigated and compared with those of the intact cells. The optimal pH was 8.5 for the immobilized cells and 10.5 for the intact cells. The aspartase activities of immobilized and intact cells were not activated by Mn(2+), which can activate the immobilized and native aspartases. The heat stability of the immobilized cells was somewhat higher than that of the intact cells. Bivalent metal ions such as Mn(2+), Mg(2+), Ca(2+) protected against thermal inactivation of the aspartase activity of the immobilized and intact cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208512"} {"pmid": "4208513", "title": "Proteinase activity in slow lactic acid-producing variants of Streptococcus lactis.", "content": "Proteinase activity in slow lactic acid-producing variants of Streptococcus lactis. Variants of Streptococcus lactis that produce lactic acid slowly in milk were isolated by inducing plasmid loss in the wild type at 39 to 40 C. Such strains had lost most of their surface-bound proteinase activity and were designated prt(-). The specific proteinase activities of S. lactis C10 prt(+) whole cells and solubilized cell walls were 7 and 18 times, respectively, those of the prt(-) strain, but spheroplast lysates of prt(+) and prt(-) strains contained similar proteinase activity. S. lactis H1 showed a similar relative distribution of activity between prt(+) and prt(-) cellular fractions, although the overall level was lower. The limited growth in milk, characteristic of prt(-) strains, can be explained in terms of their low surface-bound proteinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208513"} {"pmid": "4208514", "title": "Membrane filter method for the isolation and enumeration of Pseudomonas aeruginosa from swimming pools.", "content": "Membrane filter method for the isolation and enumeration of Pseudomonas aeruginosa from swimming pools. A membrane filter technique using black membrane filters, MacConkey agar and fluorescence under ultraviolet (UV) light was investigated for the quantitative isolation of Pseudomonas aeruginosa from swimming pools. Three thousand four hundred forty-five samples were collected from public swimming pools and enumerated by this method over a 6-month period. Fluorescent cultures were isolated from 222 specimens. Seventy-seven of these fluorescent cultures were selected for biochemical screening, with 75 (97%) being verified as P. aeruginosa. To further assess the specificity and sensitivity of this UV screening technique, a comparative study was made of some morphological and biochemical characteristics of fluorescent pseudomonads obtained from different sources. The sensitivity of the method was unimpaired by either colony types or biochemical variations of P. aeruginosa. The failure of the other two fluorescent species, P. fluorescens and P. putida, to grow and/or fluoresce on MacConkey agar at 37 C illustrates the specificity of this technique. Further studies are needed to compare the viability of P. aeruginosa on MacConkey agar to that of efficacious nonselective media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208514"} {"pmid": "4208516", "title": "Evaluation of fetal risk resulting from cord-entanglements during parturition.", "content": "Evaluation of fetal risk resulting from cord-entanglements during parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208516"} {"pmid": "4208517", "title": "Sialic acid content of cortical bone.", "content": "Sialic acid content of cortical bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208517"} {"pmid": "4208519", "title": "Preparation of immobilized lactase. Continued studies on the enzymatic hydrolysis of lactose.", "content": "Preparation of immobilized lactase. Continued studies on the enzymatic hydrolysis of lactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208519"} {"pmid": "4208518", "title": "AMP-aminohydrolase of human skeletal muscle: partial purification and properties.", "content": "AMP-aminohydrolase of human skeletal muscle: partial purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208518"} {"pmid": "4208524", "title": "Distribution and biochemical effects of pentylenetetrazol in brains of swine treated with a polychlorinated biphenyl.", "content": "Distribution and biochemical effects of pentylenetetrazol in brains of swine treated with a polychlorinated biphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208524"} {"pmid": "4208526", "title": "Partial characterization of aerolysin, a lytic exotoxin from Aeromonas hydrophila.", "content": "Partial characterization of aerolysin, a lytic exotoxin from Aeromonas hydrophila. Conditions are defined for the production, in high titers, of an extracellular hemolytic toxin of Aeromonas hydrophila, here termed \"aerolysin.\" Substantial purification of the toxin was accomplished by means of salt fractionation, dialysis, and gel filtration, with a yield of 24% of the starting activity. Analysis of the product by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate revealed a single, heavy protein band and a number of faint protein bands. The estimated molecular weight of the heavy band (50,000) was in close agreement with that (53,000) of the substance responsible for hemolytic activity as determined by gel filtration. Purified aerolysin is a labile substance, apparently protein. It is not inactivated by any of several proteases under the conditions employed nor is it inhibited by any of several lipids tested. About 0.1 mug administered to mice intravenously is lethal. The physical properties of aerolysin show considerable resemblance to those described for the exotoxin of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208526"} {"pmid": "4208527", "title": "Characterization and evaluation of a soluble antigen complex prepared from the yeast phase of Histoplasma capsulatum.", "content": "Characterization and evaluation of a soluble antigen complex prepared from the yeast phase of Histoplasma capsulatum. Soluble yeast-phase (YPS) antigen preparations (Reeves et al., 1972) were obtained from three strains of Histoplasma capsulatum. These were analyzed by agar-gel diffusion and complement fixation tests with human sera from known cases of histoplasmosis. Two of the preparations contained the H and M antigens normally found in histoplasmin, whereas the third preparation contained the H but not the M antigen. In addition, a group of unknown antigens, designated as the Y (yeast) antigens, were demonstrated in all three YPS preparations. On the basis of Sephadex gel filtration data, the molecular weight of the YPS M antigen was estimated to range from 117,000 to greater than 200,000; that of the YPS H antigen was estimated to range from about 60,000 to greater than 200,000; and that of the Y antigens was estimated to range from less than 10,000 to 100,000. Complement fixation tests with human homologous and heterologous sera showed that the Y antigens were specific for H. capsulatum; Y antigens were not detected in the single lot of histoplasmin used in this study. When 60 human histoplasmosis sera and serum samples from nine animals experimentally infected with H. capsulatum were analyzed, it was found that antibodies to the Y antigens occurred with about the same frequency as antibodies to the H antigen but with less frequency than that of antibodies to the M antigen. When used in rabbits as immunogens for the preparation of specific antisera to H. capsulatum, the components of the YPS preparations caused the formation of numerous cross-reacting antibodies. The data from this study show that the value of the YPS preparations for the serological diagnosis of histoplasmosis rests on the specificity of the H, M, and Y antigens and on the fact that the primary production of antibodies is restricted to these antigens in the course of natural infections. The YPS preparations were found to be stable for a period of at least 11 months under a variety of storage conditions and temperatures. Data obtained with various killing agents and metabolic inhibitors suggest an improved method for preparing the YPS antigens by using a suitable strain and killing the cells with iodoacetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208527"} {"pmid": "4208528", "title": "Isolation of substances responsible for lymphokine activity from sensitized mouse spleen cells.", "content": "Isolation of substances responsible for lymphokine activity from sensitized mouse spleen cells. Cultures of brucella-sensitized mouse spleen cells exposed to Brucella abortus antigens in vitro release macrophage migration inhibition factor (MIF) and macrophage spreading factor. Subjecting the supernatants from such cultures to preparative scale electrophoresis in acrylamide gel yields several fractions, one of which contains both MIF and macrophage spreading factor. This material has properties attributable to guinea pig MIF: it is nondialyzable, heat stable, nontoxic to macrophages from heterologous murine donors, and has a greater anodal electrophoretic mobility than guinea pig serum albumin. Another fraction from the gel column inhibits macrophage spreading; its electrophoretic mobility is similar to that of guinea pig gamma globulin. Neither brucella antigen nor skin reactive substances were detectable in any acrylamide gel column fraction when tested by the mouse footpad induration assay technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208528"} {"pmid": "4208529", "title": "New streptococcal serotypes causing pyoderma and acute glomerulonephritis types 59,60, and 61.", "content": "New streptococcal serotypes causing pyoderma and acute glomerulonephritis types 59,60, and 61. Three new streptococcal M serotypes, types 59, 60, and 61; have been described. They were first isolated from patients with pyoderma and acute glomerulonephritis (AGN), seen during epidemiological studies in Alabama. A possible antigenic relationship between types 59 and 61 was suggested by their T-agglutination reactions; a more specific T antiserum prepared for type 59 was useful in separating these two types, as well as other strains known to share T antigens 11, 12, and 5/27/44. On the basis of precipitin tests, a common antigenic determinant among types 59, 61, and 49 was suggested. This is of interest in view of the relation between these types and AGN. Type 59 has been relatively more widespread in distribution than type 61, but neither have been related to epidemic AGN. Type 60, first identified as \"T-4,\" thus being related to previously described M types which share this antigen, is of great interest in terms of the epidemiology of AGN. Most strains in our collection were recovered from patients with pyoderma and AGN or from their infected siblings. Recently, the type was found to be prevalent among patients with pyoderma and AGN seen in Trinidad. Data reported in relation to these new types further illustrate the dichotomy in M serotypes common to pyoderma and AGN on the one hand and those types found in collections of patients with pharyngitis on the other hand. The high rate of non-M-typable streptococci among pyoderma collections, encountered earlier, is best explained by lack of suitable reference antisera available for prevalent pyoderma serotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208529"} {"pmid": "4208530", "title": "Bacterial clearance and endocarditis in American opossums.", "content": "Bacterial clearance and endocarditis in American opossums. The American opossum is the only experimental animal that regularly develops bacterial endocarditis spontaneously. There was no relation between the ability of opossums to clear bacteria from the bloodstream and the subsequent development of endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208530"} {"pmid": "4208531", "title": "Suppression of growth of Ehrlich ascites tumor cells in mice by trehalose-6,6'-dimycolate (cord factor) and BCG.", "content": "Suppression of growth of Ehrlich ascites tumor cells in mice by trehalose-6,6'-dimycolate (cord factor) and BCG. Growth of Ehrlich ascites tumor cells in mice pretreated with cord factor was compared to growth of the tumor cells after pretreatment with Calmette-Guérin bacilli. Growth of Ehrlich ascites cells was strongly inhibited in the peritoneal cavities of mice pretreated with 80 mug of cord factor. The median survival time of the animals was prolonged (70 versus 17 days), and 40% of the mice survived more than 90 days. Tumor suppression was still detectable 36 days after administration of cord factor. The effect of cord factor was local. Comparable results were obtained with living or killed Calmette-Guérin bacilli. The results are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208531"} {"pmid": "4208532", "title": "Activity of carbenicillin and ticarcillin against Pseudomonas aeruginosa compared by paired in vitro tests.", "content": "Activity of carbenicillin and ticarcillin against Pseudomonas aeruginosa compared by paired in vitro tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208532"} {"pmid": "4208533", "title": "Experience with low temperature storage of bacteria and fungi.", "content": "Experience with low temperature storage of bacteria and fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208533"} {"pmid": "4208523", "title": "Prevention of hemolysis induced by ellipticine (NSC-71795) in rhesus monkeys.", "content": "Prevention of hemolysis induced by ellipticine (NSC-71795) in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208523"} {"pmid": "4208535", "title": "Total synthesis of bisnorpenicillin V.", "content": "Total synthesis of bisnorpenicillin V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208535"} {"pmid": "4208536", "title": "Antimicrobial activity of 8-deazafolic acid.", "content": "Antimicrobial activity of 8-deazafolic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208536"} {"pmid": "4208539", "title": "Tetrathionate broth as a medium for simultaneous demonstration of Salmonella and Pseudomonas aeruginosa.", "content": "Tetrathionate broth as a medium for simultaneous demonstration of Salmonella and Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208539"} {"pmid": "4208541", "title": "Polychlorinated biphenyl toxicity to Japanese quail as related to degree of chlorination.", "content": "Polychlorinated biphenyl toxicity to Japanese quail as related to degree of chlorination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208541"} {"pmid": "4208542", "title": "Differences in response of caged White Leghorn layers to various polychlorinated biphenyls (PCBs) in the diet.", "content": "Differences in response of caged White Leghorn layers to various polychlorinated biphenyls (PCBs) in the diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208542"} {"pmid": "4208543", "title": "Surface changes in the epicardium of chickens fed polychlorinated biphenyls.", "content": "Surface changes in the epicardium of chickens fed polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208543"} {"pmid": "4208544", "title": "Selection for body weight at eight weeks of age. 13. Fecundity.", "content": "Selection for body weight at eight weeks of age. 13. Fecundity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208544"} {"pmid": "4208545", "title": "Transplantation of posterior polar plasm in Drosophila. Induction of germ cells at the anterior pole of the egg.", "content": "Transplantation of posterior polar plasm in Drosophila. Induction of germ cells at the anterior pole of the egg. In Drosophila melanogaster the primordial germ cells are normally formed at the posterior tip of the egg during the preblastoderm stage. In order to determine whether the posterior polar plasm is capable of inducing the formation of primordial germ cells in another region of the embryo, portions of this cytoplasm were transferred from wild-type embryos of the early cleavage stage to the anterior tip of mwh e embryos of the same age. At various times after the injection (15-200 min), embryos were fixed for histological analysis. Alternating thick and thin sections were examined for the presence of experimentally induced pole cells. In more than half of the embryos analyzed in this way, one to six cells were found containing the polar granules as well as round nuclear structures, both of which are characteristic of normal pole cells and are not present in blastoderm cells. In order to determine whether these \"pole cells\" function normally, i.e., develop further into germ cells, the cells induced at the anterior tip of mwh e blastoderm embryos were introduced into the posterior region of y w sn(3) hosts of the same age. The flies resulting from these embryos were mated to y w sn(3) partners. In addition to the expected y w sn(3) progeny, wild-type flies heterozygous for mwh e and, therefore, descended from the experimentally induced pole cells were found in 4% of the crosses. Such flies did not appear in the control experiments after transfer of normal anterior cells from noninjected blastoderm embryos. These results demonstrate that the posterior polar plasm can be transferred to the anterior tip of the embryo and that in this presumptive somatic region it still retains its capacity to determine the formation of the primordial germ cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208545"} {"pmid": "4208546", "title": "A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.", "content": "A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Dialyzed serum from clotted monkey blood (\"blood serum\") promotes the proliferation of monkey arterial smooth muscle cells in culture, but dialyzed serum prepared from recalcified platelet-poor plasma (\"plasma serum\") is much less effective. Addition of platelets and calcium to platelet-poor plasma increases the activity of plasma serum to the same level achieved with blood serum. Furthermore, addition to plasma serum of a platelet-free supernatant prepared by exposing purified platelets to thrombin also stimulates the proliferation of smooth muscle cells. Thus, much of the growth-promoting activity of dialyzed serum is directly or indirectly derived from platelets. This finding has important implications for the response of arteries to localized injury and provides a key to further understanding of the role of factors derived from blood serum in promoting cell proliferation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208546"} {"pmid": "4208547", "title": "Unequal mitotic sister chromatin exchange as the mechanism of ribosomal RNA gene magnification.", "content": "Unequal mitotic sister chromatin exchange as the mechanism of ribosomal RNA gene magnification. It is hypothesized that magnification of the gene coding for ribosomal RNA occurs by unequal mitotic sister chromatid exchange on the basis of five different lines of evidence. These are: (1) rDNA magnification occurs in mitotically active germ cells; (2) decreases in rDNA redundancy can be genetically produced, a phenomenon termed reduction; (3) magnification and reduction events are reversible and reciprocal; (4) it is possible to generate bb(+) and bb somatic bristle mosaics (bb mutants are partially deficient for rRNA genes); and (5) magnification of bb in a ring X chromosome is reduced. Implications of these results and the unequal sister exchange (USE) hypothesis are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208547"} {"pmid": "4208549", "title": "Genetic control of imaginal disc development in Drosophila.", "content": "Genetic control of imaginal disc development in Drosophila. Many of the functions required for formation of the imaginal discs of Drosophila melanogaster larvae, from which adult structures are derived, are disc-specific and not required for formation of other larval tissues. Mutants blocked in disc-specific functions can produce mature viable larvae, indicating that larval development is not dependent on concomitant disc development. Some of the mutant larvae have no detectable discs (discless mutants), and other have small discs that cannot differentiate into adult structures (small disc mutants). From the results of genetic complementation and mapping experiments with such mutants, it was estimated that the genome of D. melanogaster contains around a thousand complementation groups, or about a fifth of all complementation groups in the genome, that are essential specifically for the development of all the discs. The developmental defects in some of the disc mutants appear to involve autonomous functions of the imaginal cells, and in other mutants functions provided by the larval environment to support disc development. This distinction was made on the basis of two functional tests. The purpose of one of the tests was to detect the presence in young embryos of determined imaginal cells capable of differentiating after transplantation to a wild-type host; the other test measured the capacity of early third-instar larvae to act as hosts for the further development of immature discs transplanted from a wild-type donor. Three discless mutants that were tested in this way appeared to be defective in autonomous functions of the imaginal cells, since the embryos contained no imaginal cells that could be detected in the first test, whereas the larvae, although devoid of discs, showed a normal capacity to support disc development in the second test. One of the small disc mutants tested was defective in a larval rather than an imaginal cell function, since the embryos had a normal complement of functional imaginal cells, whereas the larvae were incapable of supporting disc development. Thus, both types of disc-specific functions are essential for normal disc development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208549"} {"pmid": "4208548", "title": "Kinetic evidence for the presence of two prostaglandin receptor sites regulating the activity of intestinal adenylate cyclase sensitive to Escherichia coli enterotoxin.", "content": "Kinetic evidence for the presence of two prostaglandin receptor sites regulating the activity of intestinal adenylate cyclase sensitive to Escherichia coli enterotoxin. Kinetic behavior most consistent with the presence of two independent, but simultaneously acting, regulatory effector sites for prostaglandins has been presented for adenylate cyclase (EC 4.6.1.1) of rabbit intestinal epithelial cells. One site regulates activation of the catalytic site, while the other site regulates inhibition. A synthetic prostaglandin analogue, 7-oxa-13-prostynoic acid, is recognized at both sites in a concentration-dependent manner. At concentrations of 7-oxa-13-prostynoic acid less than 45 mug/ml, activation is seen, while at higher concentrations, inhibition is seen. Different naturally occurring prostaglandins appear to be site-specific. Prostaglandin E(1) gives only activation of the cyclase, while prostaglandin A(1) gives only inhibition of the activated cyclase. When saturating concentrations of prostaglandin E(1) are used to activate adenylate cyclase, no further activation by 7-oxa-13-prostynoic acid can be elicited, indicating that both molecules activate at the same site. The similarity of inhibition constants for both 7-oxa-13-prostynoic acid and prostaglandin A(1) suggests that the mode of binding is the same for both compounds and that they probably inhibit by acting at the same site. The inhibition by 7-oxa-13-prostynoic acid and by prostaglandin A(1) overrides enzyme activation produced by either Escherichia coli enterotoxin, prostaglandin E(1), or sodium fluoride, suggesting that in intestinal adenylate cyclase this site is the primary regulatory site (i.e., primary allosteric effector site) for enzyme activity. These data suggest that sites exist on adenylate cyclase which would allow prostaglandins to serve as the intracellular messengers by which the cell controls its adenylate-cyclase-mediated response to extracellular stimulation, as with hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208548"} {"pmid": "4208550", "title": "Evidence for the presence of the toxin-binding protein on the plasma membrane of sugarcane cells.", "content": "Evidence for the presence of the toxin-binding protein on the plasma membrane of sugarcane cells. Helminthosporoside is a host-specific toxin produced by Helminthosporium sacchari, both in culture and in infected sugarcane tissue. The susceptibility of any given clone of sugarcane to disease is invariably associated with the presence of a toxin-binding protein. This report presents evidence for the presence of the toxin-binding protein on the plasma membrane of the plant cell. This evidence includes, among others: (1) The protection of susceptible plant tissues by prior treatment with antiserum to the binding protein, (2) the successful pyridoxylation and reduction of the binding protein in vivo followed by its isolation, (3) the reaction of sugarcane cells and free protoplasts with [(3)H]antiserum prepared against the binding protein, and (4) the agglutination of sugarcane protoplast preparations with antiserum to the binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208550"} {"pmid": "4208551", "title": "Partial purification of detergent-soluble HL-A antigen and its cleavage by papain.", "content": "Partial purification of detergent-soluble HL-A antigen and its cleavage by papain. HL-A antigen solubilized with the non-ionic detergent, Brij 99, has been purified to about 50% of homogeneity from a cultured human lymphoblast line. It consists of two nonidentical subunits of 44,000 and 12,000 molecular weight (MW). Upon papain proteolysis the 44,000 MW peptide is converted by at least two cleavages to a 34,000 MW peptide, but the 12,000 MW peptide appears to be unchanged. Concomitantly, the apparent molecular weight in gel filtration chromatography under nondenaturing conditions in the presence of Brij 99 is reduced from 460,000 to 45,000. HL-A molecules produced by direct papain proteolysis of membranes and by papain treatment of purified detergent-soluble HL-A are identical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208551"} {"pmid": "4208557", "title": "Epileptic fits in cysticercosis.", "content": "Epileptic fits in cysticercosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208557"} {"pmid": "4208556", "title": "Tuberculosis survey in East Central State, Nigeria: implications for tuberculosis programme development.", "content": "Tuberculosis survey in East Central State, Nigeria: implications for tuberculosis programme development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208556"} {"pmid": "4208558", "title": "Use of sulfadiazine in the prophylaxis of group A meningococcal carriers in Egypt.", "content": "Use of sulfadiazine in the prophylaxis of group A meningococcal carriers in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208558"} {"pmid": "4208559", "title": "Pediatric urinary tract infection. Significance of vaginal bacteria.", "content": "Pediatric urinary tract infection. Significance of vaginal bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208559"} {"pmid": "4208565", "title": "A simplified and rapid direct method for the determination of triiodothyronine in human serum.", "content": "A simplified and rapid direct method for the determination of triiodothyronine in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208565"} {"pmid": "4208568", "title": "Scanning electron microscopy on the distribution of the minute blood vessels in the thyroiod gland of the dog, rat and rhesus monkey.", "content": "Scanning electron microscopy on the distribution of the minute blood vessels in the thyroiod gland of the dog, rat and rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208568"} {"pmid": "4208567", "title": "Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis.", "content": "Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis. When an actively growing culture of the H37Ra strain of Mycobacterium tuberculosis was exposed to isoniazid at a concentration of 0.5 mug/ml, the cells began to lose their ability to synthesize mycolic acids immediately. After 60 min, the cells had completely lost this ability. The synthesis of the three mycolate components-alpha-mycolate, methoxymycolate, and beta-mycolate-was inhibited. The viability of the isoniazid-treated cells was unaffected up to about 60 min of exposure, after which time there was a gradual decline in the viability to about 18% after 180 min. Correspondingly, growth of the drug-treated cells slowed down and stopped after 24 hr. The inhibition of the synthesis of mycolic acids was reversible if the drug was removed before the loss of viability set in. Incubation of the viable cells in the absence of the drug for 24 hr restored the mycolate synthesis. These results strongly suggest that the inhibition of the synthesis of the mycolic acids is closely associated with the primary mechanism of action of isoniazid on the tubercle bacilli. The sequence of events which leads to the loss of viability of cells exposed to isoniazid is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208567"} {"pmid": "4208569", "title": "Activation of prephenoloxidase. 3. Release of a peptide from prephenoloxidase by the activating enzyme.", "content": "Activation of prephenoloxidase. 3. Release of a peptide from prephenoloxidase by the activating enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208569"} {"pmid": "4208570", "title": "Dissociation of tetanus neurotoxin into two polypeptide fragments.", "content": "Dissociation of tetanus neurotoxin into two polypeptide fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208570"} {"pmid": "4208571", "title": "Enzymatic breakdown of tetanus toxin.", "content": "Enzymatic breakdown of tetanus toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208571"} {"pmid": "4208572", "title": "Chemical modification of the tryptophan residue in toxin B from the venom of the Indian cobra.", "content": "Chemical modification of the tryptophan residue in toxin B from the venom of the Indian cobra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208572"} {"pmid": "4208574", "title": "The pathology of experimental lead encephalopathy in the baboon (Papio anubis).", "content": "The pathology of experimental lead encephalopathy in the baboon (Papio anubis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208574"} {"pmid": "4208573", "title": "Quantitative aspects of ribosomal RNA synthesis during ovarian development in two mutants of Drosophila melanogaster.", "content": "Quantitative aspects of ribosomal RNA synthesis during ovarian development in two mutants of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208573"} {"pmid": "4208577", "title": "Delta-aminolevulinic acid synthetase activity in normal human bone marrow and in patients with idiopathic sideroblastic anemia.", "content": "Delta-aminolevulinic acid synthetase activity in normal human bone marrow and in patients with idiopathic sideroblastic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208577"} {"pmid": "4208578", "title": "Regulatory link between lactate dehydrogenase and biosynthesis of porphyrin and heme in microorganisms.", "content": "Regulatory link between lactate dehydrogenase and biosynthesis of porphyrin and heme in microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208578"} {"pmid": "4208579", "title": "Effect of oxygen on heme and cytochrome content in some facultative bacteria.", "content": "Effect of oxygen on heme and cytochrome content in some facultative bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208579"} {"pmid": "4208580", "title": "Role of oxygen in the late steps of heme synthesis in pseudomonads and Escherichia coli.", "content": "Role of oxygen in the late steps of heme synthesis in pseudomonads and Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208580"} {"pmid": "4208581", "title": "Comparison of porphyrin and heme biosynthesis in various heterotrophic bacteria.", "content": "Comparison of porphyrin and heme biosynthesis in various heterotrophic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208581"} {"pmid": "4208583", "title": "Peptic digestion of pig IgM.", "content": "Peptic digestion of pig IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208583"} {"pmid": "4208584", "title": "Equine anti-hapten antibody. 8. Isoelectric fractions of IgM and 7S anti-lactose antibody.", "content": "Equine anti-hapten antibody. 8. Isoelectric fractions of IgM and 7S anti-lactose antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208584"} {"pmid": "4208585", "title": "Does J chain mediate the combination of 19S IgM and dimeric IgA with the secretory component rather than being necessary for their polymerization?", "content": "Does J chain mediate the combination of 19S IgM and dimeric IgA with the secretory component rather than being necessary for their polymerization?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208585"} {"pmid": "4208586", "title": "The membranes of the basal labyrinth in kidney cells of the stickleback, Gasterosteus aculeatus, studied in ultrathin sections and freeze-etch replicas.", "content": "The membranes of the basal labyrinth in kidney cells of the stickleback, Gasterosteus aculeatus, studied in ultrathin sections and freeze-etch replicas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208586"} {"pmid": "4208589", "title": "Spermatogenesis in pharate adult testes of Drosophila in tissue cultures without ecdysones.", "content": "Spermatogenesis in pharate adult testes of Drosophila in tissue cultures without ecdysones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208589"} {"pmid": "4208588", "title": "Differentiation in breast cancer.", "content": "Differentiation in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208588"} {"pmid": "4208587", "title": "Clinical value of tumour-associated antigens.", "content": "Clinical value of tumour-associated antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208587"} {"pmid": "4208606", "title": "Palindromes in chromosomes.", "content": "Palindromes in chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208606"} {"pmid": "4208607", "title": "The structure of psi DNA.", "content": "The structure of psi DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208607"} {"pmid": "4208608", "title": "Vaginal flap incision for urethral diverticulectomy.", "content": "Vaginal flap incision for urethral diverticulectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208608"} {"pmid": "4208609", "title": "Nocardiosis of the testis.", "content": "Nocardiosis of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208609"} {"pmid": "4208611", "title": "Serum folic acid levels and pregnancy in South Australia. A study of the factors associated with low serum folic acid levels with particular reference to racial groups and lactation.", "content": "Serum folic acid levels and pregnancy in South Australia. A study of the factors associated with low serum folic acid levels with particular reference to racial groups and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208611"} {"pmid": "4208612", "title": "Letter: The use of nebulized intal in asthma.", "content": "Letter: The use of nebulized intal in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208612"} {"pmid": "4208613", "title": "Rapid grouping of streptococci by immunoelectroosmophoresis.", "content": "Rapid grouping of streptococci by immunoelectroosmophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208613"} {"pmid": "4208616", "title": "The establishment of rumen ciliate protozoa in sheep fed on whole barley to appetite.", "content": "The establishment of rumen ciliate protozoa in sheep fed on whole barley to appetite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208616"} {"pmid": "4208617", "title": "Autoradiographic evidence for the occurrence of cell fusion cultures of Theileria-infected bovine lymphoid cells.", "content": "Autoradiographic evidence for the occurrence of cell fusion cultures of Theileria-infected bovine lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208617"} {"pmid": "4208618", "title": "An investigation of the association between circulating antibody levels and systemic anaphylactic sensitivity in cattle.", "content": "An investigation of the association between circulating antibody levels and systemic anaphylactic sensitivity in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208618"} {"pmid": "4208619", "title": "Capsular and somatic antigens of Pasteurella multocida, types B and E.", "content": "Capsular and somatic antigens of Pasteurella multocida, types B and E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208619"} {"pmid": "4208626", "title": "Factor XII-induced fibrinolysis: studies on the separation of prekallikrein, plasminogen proactivator, and factor XI in human plasma.", "content": "Factor XII-induced fibrinolysis: studies on the separation of prekallikrein, plasminogen proactivator, and factor XI in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208626"} {"pmid": "4208629", "title": "Uses of epidemiology in housing programmes and in planning human settlements. Report of a WHO Expert Committee on Housing and Health.", "content": "Uses of epidemiology in housing programmes and in planning human settlements. Report of a WHO Expert Committee on Housing and Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208629"} {"pmid": "4208620", "title": "Histochemistry of enzymes involved in the synthesis and breakdown of glycogen in the junctional zone of the rat's placenta.", "content": "Histochemistry of enzymes involved in the synthesis and breakdown of glycogen in the junctional zone of the rat's placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208620"} {"pmid": "4208631", "title": "Retinal effects of a multiple-pulse laser.", "content": "Retinal effects of a multiple-pulse laser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208631"} {"pmid": "4208632", "title": "Metabolism of two valence states of inhaled antimony in hamsters.", "content": "Metabolism of two valence states of inhaled antimony in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208632"} {"pmid": "4208634", "title": "Immune response to Listeria monocytogenes in rabbits and humans.", "content": "Immune response to Listeria monocytogenes in rabbits and humans. Rabbits were immunized with listeria antigens, staphylococcus antigen, or with both, and the course of their immune response was monitored. Antibodies to Listeria and Staphylococcus were produced in both immunoglobulin M (IgM) and immunoglobulin G (IgG) classes in response to inoculation with the specific antigen. Cross-responses occurred in rabbits injected only with Listeria or only with Staphylococcus, as well as in rabbits injected with both antigens. L. monocytogenes serotype 4d appeared to be immunologically distinct from L. monocytogenes serotype 2 and its cross-reaction with S. aureus. Human sera from bacteriologically confirmed cases of listeriosis were examined to determine the nature of the immunological response of man to Listeria. In the sera studied, IgM was the predominant antibody produced to Listeria, whereas cross-reactions with Staphylococcus were observed in both the IgM and the IgG antibody classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208634"} {"pmid": "4208635", "title": "Resistance to gonorrhea possibly mediated by bacterial interference.", "content": "Resistance to gonorrhea possibly mediated by bacterial interference. Two men with no prior history of urethritis failed to develop gonorrhea after sexual exposures to women with genital gonococcal infection. Usual methods of prophylaxis, such as antibiotics or condoms, were not employed. The aerobic bacterial flora of these men's urethras consisted of several bacteria, some of which inhibited the in vitro growth of Neisseria gonorrhoeae. The hypothesis is suggested that bacterial interference may have played a role in protecting these men from gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208635"} {"pmid": "4208636", "title": "Rapid detection of Clostridium botulinum toxin by capillary tube diffusion.", "content": "Rapid detection of Clostridium botulinum toxin by capillary tube diffusion. A micro capillary agar-gel diffusion system for the detection of botulinal toxin in foods and cultures was developed and evaluated. Toxins types A, B, and E, produced in culture broth with and without added trypsin, and type E toxin, produced in inoculated canned clams, were tested with this system and with the mouse bioassay procedure. With nontrypsinized toxin, the capillary diffusion system detected as little as 100 minimal lethal doses (MLD) per ml but was effective only at higher levels, 10(6) to 1.5 x 10(7) MLD/ml, when used with trypsinized toxin. The inability to detect lower levels of trypsinized toxin was due to thioglycolate present in the medium used to produce toxin. Evidently, trypsinization of toxin produces polypeptides still held together by disulfide bonds. Cleavage of these bonds by reduction with thioglycolate reduces the sensitivity of the capillary method. Trypsinized toxin produced in broth without thioglycolate was detected as readily as nontrypsinized toxin. Toxin was detected in canned clams containing as low as 100 MLD/ml. No cross-reactions were observed with type E toxin and types A and B antitoxins. Extensive studies using the capillary method for detecting types A and B toxins were not performed; however, a suspected sample of commercially canned mushrooms gave a positive type B reaction but not a type A reaction. This typing was confirmed later by the mouse bioassay. Toxin was present at a level of 100 MLD/ml. The procedure developed may prove useful as a rapid screening method for the detection of botulinal toxin in foods, with final identification made by using the mouse bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208636"} {"pmid": "4208637", "title": "NYC medium for simultaneous isolation of Neisseria gonorrhoeae, large-colony mycoplasmas, and T-mycoplasmas.", "content": "NYC medium for simultaneous isolation of Neisseria gonorrhoeae, large-colony mycoplasmas, and T-mycoplasmas. NYC medium, primarily designed for isolation of pathogenic Neisseria, also readily supports the growth of large-colony mycoplasmas and T-mycoplasmas. When compared with A-3 agar medium and PPLO agar in clinical field trials, NYC medium performed equally as well as these mycoplasma-specific media in providing recovery of Mycoplasma species from female genital specimens. The transparent, highly-selective NYC medium permits direct, microscopic observation and presumptive identification of mycoplasmas, as well as Neisseria gonorrhoeae, without interference from contaminating saprophytes. As a single medium it can therefore be doubly useful in the diagnosis of gonorrhea and in the recognition of active or asymptomatic mycoplasma infections. Used in gonorrhea screening programs, the medium can be valuable in establishing the frequency of association of mycoplasmas with urogenital tract infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208637"} {"pmid": "4208638", "title": "Retention of 14C-labeled tuberculin purified protein derivative in the skin of sensitized and nonsensitized animals.", "content": "Retention of 14C-labeled tuberculin purified protein derivative in the skin of sensitized and nonsensitized animals. Tuberculin purified protein derivative labeled with (14)C ([(14)C]PPD) with a biological potency equivalent to the International Standard for tuberculin PPD was used to study the retention of tuberculin PPD in the skin of sensitized and nonsensitized animals. We found that [(14)C]PPD was almost entirely cleared from the skin test site during the first 18 to 24 h after injection and that when approximately 5% of the initial concentration of [(14)C]PPD was present in the skin test site, the size of the tuberculin skin reaction in sensitized guinea pigs was at its maximum. Furthermore, the addition of 5 or 50 mug of Tween 80 per ml to a solution of PPD did not change either the rate of clearance of PPD from the skin test sites of sensitized guinea pigs or the size of the tuberculin skin reactions. There was no difference in the rate of clearance of [(14)C]PPD from the skin test sites between sensitized and nonsensitized guinea pigs and between guinea pigs of different age. However, there was a significant difference in the rate of clearance of [(14)C]PPD between the guinea pig and the mouse. Finally, the percentage of [(14)C]PPD retained in the site of injection at 24 h was in the neighborhood of 5% of the initial concentration of the solution of PPD injected. The significance of these phenomena is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208638"} {"pmid": "4208639", "title": "Aflatoxin-producing strains of Aspergillus flavus detected by fluorescence of agar medium under ultraviolet light.", "content": "Aflatoxin-producing strains of Aspergillus flavus detected by fluorescence of agar medium under ultraviolet light. The fluorescence method of detecting aflatoxin-producing strains of Aspergillus flavus and related species utilizes the ultraviolet-induced fluorescence of aflatoxin produced in a modified Czapek's solution agar containing corn steep liquor, HgCl(2), and (NH(4))H(2)PO(4) instead of NaNO(3). The presence of aflatoxin is confirmed by thin-layer chromatography of CHCl(3) extracts of the fluorescing agar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208639"} {"pmid": "4208640", "title": "Plaque assay of rickettsiae in a mammalian cell line.", "content": "Plaque assay of rickettsiae in a mammalian cell line. Clear-cut and repeatable plaque assays were obtained for three rickettsiae of the spotted fever group (Rickettsia rickettsi, R. conori, and R. montana) in Vero cells used in a manner similar to that for arboviruses. In addition, three typhus group agents (R. typhi, R. canada, R. prowazeki) induced plaques in these cells. In preliminary tests Coxiella burneti (Nine Mile strain) failed to produce plaques. Comparable results were obtained in plastic flasks and plastic culture trays incubated in ambient air with or without addition of N-2-hydroxyethyl-piperazine-N'-2-ethanesulfinic acid buffer. Larger and more well defined R. rickettsi plaques were produced when cultures were overlaid with Leibovitz (L15) medium than with either medium 199 or Eagle medium. Phosphate-buffered saline containing bovine plasma albumin (fraction V), in contrast to brain heart infusion broth, as a diluent for preparing inocula consistently permitted development of larger and more numerous plaques with three agents: R. rickettsi, R. conori, and R. montana. When R. rickettsi and R. typhi were assayed in parallel in primary chicken embryo cultures and Vero cells, comparable results were obtained, but with R. canada results in Vero cells were superior. In contrast, R. prowazeki produced inconsistent results in Vero cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208640"} {"pmid": "4208641", "title": "Epidemiological tracing of Pseudomonas aeruginosa: antibiogram and serotyping.", "content": "Epidemiological tracing of Pseudomonas aeruginosa: antibiogram and serotyping. The spread of a particular strain of Pseudomonas aeruginosa through a pediatric burn unit was monitored using serological typing and antibiotic susceptibility data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208641"} {"pmid": "4208642", "title": "Raman spectroscopy in vivo: evidence on the structure of dipicolinate in intact spores of Bacillus megaterium.", "content": "Raman spectroscopy in vivo: evidence on the structure of dipicolinate in intact spores of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208642"} {"pmid": "4208643", "title": "Anomalous molecular weights to proteases in gel chromatography.", "content": "Anomalous molecular weights to proteases in gel chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208643"} {"pmid": "4208644", "title": "Ribsome and messenger specificity in protein synthesis by bacteria.", "content": "Ribsome and messenger specificity in protein synthesis by bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208644"} {"pmid": "4208645", "title": "Exploitation of the oxygen enhancement ratio in clinical practice.", "content": "Exploitation of the oxygen enhancement ratio in clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208645"} {"pmid": "4208646", "title": "Effects of radiation dose-rate from protracted, continuous irradiation to ultra-high dose-rates from pulsed accelerators.", "content": "Effects of radiation dose-rate from protracted, continuous irradiation to ultra-high dose-rates from pulsed accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208646"} {"pmid": "4208647", "title": "Cortical motor representation of the laryngeal muscles in Macaca mulatta.", "content": "Cortical motor representation of the laryngeal muscles in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208647"} {"pmid": "4208648", "title": "The postnatal development of antigens on mouse brain cell surfaces.", "content": "The postnatal development of antigens on mouse brain cell surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208648"} {"pmid": "4208649", "title": "Metabolism of acid-soluble nucleotides in starved-refed-synchronized Tetrahymena pyriformis GL.", "content": "Metabolism of acid-soluble nucleotides in starved-refed-synchronized Tetrahymena pyriformis GL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208649"} {"pmid": "4208651", "title": "Genetic, cytological, and ultrastructural characterization of a temperature-sensitive lethal in Drosophila melanogaster.", "content": "Genetic, cytological, and ultrastructural characterization of a temperature-sensitive lethal in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208651"} {"pmid": "4208652", "title": "Radioimmunoassay of rat parathyroid hormone in serum and tissue extracts.", "content": "Radioimmunoassay of rat parathyroid hormone in serum and tissue extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208652"} {"pmid": "4208650", "title": "The organization and gross mineralization patterns of the collagen fibres in Sharpey fibre bone.", "content": "The organization and gross mineralization patterns of the collagen fibres in Sharpey fibre bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208650"} {"pmid": "4208653", "title": "Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat.", "content": "Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208653"} {"pmid": "4208654", "title": "Stimulation of prolactin release in vivo by thyrotropin-releasing hormone (TRH) through direct action on the ectopic rat pituitary.", "content": "Stimulation of prolactin release in vivo by thyrotropin-releasing hormone (TRH) through direct action on the ectopic rat pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208654"} {"pmid": "4208655", "title": "Neurological and psychomotor functions in children with an increased lead burden.", "content": "Neurological and psychomotor functions in children with an increased lead burden. Fifty-eight children with an increased lead burden underwent comprehensive investigations and were reevaluated 1(1/2) to 3 years later. Of these children 23-27% were noted to have minor neurological dysfunction and various forms of motor impairment during each evaluation. While the initial psychological assessment revealed low average mental abilities in the majority of children, during follow-up examination a significant increase in certain areas of intellectual functioning was observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208655"} {"pmid": "4208656", "title": "Biochemical and toxicological response of infant baboons to lead driers in paint.", "content": "Biochemical and toxicological response of infant baboons to lead driers in paint. In an effort to define the toxicology and disposition of lead compounds that presently exist in paint (i.e., organic driers), a controlled dose feeding study was initiated early this year with the use of 28 infant baboons as experimental animals. The infant baboon, established as a metabolic model for a child ingesting lead, will be used to determine the adequacy of present as well as recently recommended limitations for lead in paint to assure protection from this potential source of lead exposure. To accomplish this goal, research has been designed to determine basic dose-response relationships in animals ingesting constant daily doses of a dried paint, a lead octoate drier, and lead acetate. Doses for these compounds have been chosen to cover a broad range of concentrations including that recommended by the American Academy of Pediatrics from the maximum daily permissible lead ingestion, and associated estimates of paint intake by children with pica. PARAMETERS OF METABOLIC RESPONSE FOR EACH LEAD COMPOUND, INCLUDE: general clinical surveillance, lead concentrations in blood, urine and feces, erythrocytic delta-aminolevulinic acid dehydratase and free erythrocytic porphyrin. The response of several of these measures of lead exposure as a function of time will be discussed for each compound at the several dose levels administered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208656"} {"pmid": "4208657", "title": "Experimental acute lead encephalopathy in the juvenile rhesus monkey.", "content": "Experimental acute lead encephalopathy in the juvenile rhesus monkey. Lead subacetate (0.5g) and 1000 units of vitamin D were given three times a week to four newly-weaned rhesus monkeys. In addition, two animals received only the vitamin D. The poisoned animals had an increase in the urinary excretion of delta-aminolevulinic acid, an elevated content of lead in the blood, and a fall in hemoglobin concentration. Between 6 and 18 weeks the animals suddenly developed ataxia, nystagmus, generalized weakness, and convulsions. At this time the animals were killed by perfusion of fixative and the brain prepared for light and electron microscopic studies. Definite morphological evidence of disease was confined to the central nervous system, except for one animal which showed the characteristic renal inclusions of lead poisoning. All animals showed PAS-positive globules associated with blood vessels and an exudative edema involving the white matter of the cerebral hemispheres and cerebellum. Ultra-structurally, this appeared as a granular precipitate within an expanded extracellular space. Alterations of nerve fibers were not seen in the white matter but axonal swelling was observed in the cerebral cortex. The perikaryon and neuropil appeared normal. The control animals showed no significant cerebral changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208657"} {"pmid": "4208659", "title": "Influence of oxygen and pH on plating efficiency and colony development of WI-38 and Vero cells.", "content": "Influence of oxygen and pH on plating efficiency and colony development of WI-38 and Vero cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208659"} {"pmid": "4208658", "title": "Pathobiological and behavioral effects of lead intoxication in the infant rhesus monkey.", "content": "Pathobiological and behavioral effects of lead intoxication in the infant rhesus monkey. When infant rhesus monkeys were exposed to lead via the addition of lead acetate (0.5-9 mg/kg body weight) to their formula or by the consumption of lead particles from lead-based surrogate mothers, they developed symptoms of lead intoxication within 6 weeks. Seizures, muscular tremors, and altered social interaction were the predominant changes. Visual impairment was also apparent in the more severely affected animals. In the animals showing obvious symptoms lead levels varied between 300 to 500 mug/100 ml of blood. Even in those animals having blood lead levels below 100 mug, hyperactivity and insomnia were observed. When the exposure to lead was eliminated, seizures subsided and visual impairment was reduced; however, the abnormal social interaction persisted. These animals also experienced a gradual decline in hematocrit and hemoglobin values during the period of examination. Liver and kidney biopsies obtained from these lead-exposed animals revealed characteristic intranuclear inclusions.When adolescent and adult monkeys were exposed to doses of lead acetate similar to those employed in the infant experiments, lead levels in excess of 200 mug/100 ml of blood were recorded. However, there were no obvious behavioral abnormalities observed. There were, however, numerous lead inclusion bodies in kidney biopsy specimens from these animals. These data suggest that, like man, the infant nonhuman primate is much more susceptible to lead intoxication than is the adult. The clinical and behavioral changes recorded in these infant rhesus monkeys suggest their use as an experimental model to evaluate lead intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208658"} {"pmid": "4208660", "title": "Phase-dependent lobopodial contact paralysis.", "content": "Phase-dependent lobopodial contact paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208660"} {"pmid": "4208662", "title": "D-ribulose 1,5-diphosphate carboxylase from Rhodospirillum rubrum. II. Quaternary structure, composition, catalytic, and immunological properties.", "content": "D-ribulose 1,5-diphosphate carboxylase from Rhodospirillum rubrum. II. Quaternary structure, composition, catalytic, and immunological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208662"} {"pmid": "4208661", "title": "D-ribulose 1,5-diphosphate carboxylase from Rhodospirillum rubrum. I. Levels, purification, and effects of metallic ions.", "content": "D-ribulose 1,5-diphosphate carboxylase from Rhodospirillum rubrum. I. Levels, purification, and effects of metallic ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208661"} {"pmid": "4208663", "title": "On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells.", "content": "On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208663"} {"pmid": "4208664", "title": "A comparison of the L-arabinose- and D-galactose-binding proteins of Escherichia coli B-r.", "content": "A comparison of the L-arabinose- and D-galactose-binding proteins of Escherichia coli B-r.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208664"} {"pmid": "4208666", "title": "Meningococcal conjunctivitis. Report of a case.", "content": "Meningococcal conjunctivitis. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208666"} {"pmid": "4208667", "title": "Development of knowledge of unity of tuberculosis and of the portals of entry of tubercle bacilli.", "content": "Development of knowledge of unity of tuberculosis and of the portals of entry of tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208667"} {"pmid": "4208665", "title": "Purification and properties of flagellar outer doublet tubulin from Naegleria gruberi and a radioimmune assay for tubulin.", "content": "Purification and properties of flagellar outer doublet tubulin from Naegleria gruberi and a radioimmune assay for tubulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208665"} {"pmid": "4208668", "title": "A method of freeze-drying and fixing bacterial cultures for electron microscopy.", "content": "A method of freeze-drying and fixing bacterial cultures for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208668"} {"pmid": "4208669", "title": "Erroneous Model S Coulter Counter values on patients undergoing parenteral nutrition with intravenous lipid emulsions.", "content": "Erroneous Model S Coulter Counter values on patients undergoing parenteral nutrition with intravenous lipid emulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208669"} {"pmid": "4208674", "title": "Problems in geriatrics.", "content": "Problems in geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208674"} {"pmid": "4208675", "title": "Nursing procedures: you'd be amazed at what they cost. (And maybe you're not to blame).", "content": "Nursing procedures: you'd be amazed at what they cost. (And maybe you're not to blame).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208675"} {"pmid": "4208676", "title": "Cromolyn--metaproterenol.", "content": "Cromolyn--metaproterenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208676"} {"pmid": "4208677", "title": "The effect of prostaglandin E2 on the rhesus monkey pupil.", "content": "The effect of prostaglandin E2 on the rhesus monkey pupil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208677"} {"pmid": "4208678", "title": "Effects of sequential treatment with estradiol and PGF2alpha on the length of the primate menstrual cycle.", "content": "Effects of sequential treatment with estradiol and PGF2alpha on the length of the primate menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208678"} {"pmid": "4208682", "title": "Platelet aggregation induced by procollagen.", "content": "Platelet aggregation induced by procollagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208682"} {"pmid": "4208681", "title": "Biosynthetic activities in normal and pathological platelet populations.", "content": "Biosynthetic activities in normal and pathological platelet populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208681"} {"pmid": "4208683", "title": "Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) deficiency: immunologic studies on the mutant enzyme.", "content": "Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) deficiency: immunologic studies on the mutant enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208683"} {"pmid": "4208684", "title": "Immunological studies of hypoxanthine-guanine phosphoribosyltransferase in Lesch-Nyhan syndrome.", "content": "Immunological studies of hypoxanthine-guanine phosphoribosyltransferase in Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208684"} {"pmid": "4208685", "title": "Unstable HPRTase in subjects with abnormal urinary oxypurine excretion.", "content": "Unstable HPRTase in subjects with abnormal urinary oxypurine excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208685"} {"pmid": "4208686", "title": "Human hypoxanthine-guanine phosphoribosyltransferase (HGPRT): purification and properties.", "content": "Human hypoxanthine-guanine phosphoribosyltransferase (HGPRT): purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208686"} {"pmid": "4208687", "title": "The enzymatic conversion of cis-(14C)phytofluene, trans-(14C)phytofluene, and trans-zeta-(14C)carotene to poly-cis-acyclic carotenes by a cell-free preparation of tangerine tomato fruit plastids.", "content": "The enzymatic conversion of cis-(14C)phytofluene, trans-(14C)phytofluene, and trans-zeta-(14C)carotene to poly-cis-acyclic carotenes by a cell-free preparation of tangerine tomato fruit plastids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208687"} {"pmid": "4208688", "title": "Chemical modification studies of chloroplast membranes. Water oxidation inhibition by diazonium-benzenesulfonic acid.", "content": "Chemical modification studies of chloroplast membranes. Water oxidation inhibition by diazonium-benzenesulfonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208688"} {"pmid": "4208689", "title": "tRNA methylases from HeLa cells: purification and properties of an adenine-1-methylase and a guanine-N2-methylase.", "content": "tRNA methylases from HeLa cells: purification and properties of an adenine-1-methylase and a guanine-N2-methylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208689"} {"pmid": "4208690", "title": "L-Rhamnulose 1-phosphate aldolase of Escherichia coli. The role of metal in enzyme structure.", "content": "L-Rhamnulose 1-phosphate aldolase of Escherichia coli. The role of metal in enzyme structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208690"} {"pmid": "4208699", "title": "Antigenic analysis of raw soybean: variation of host response during prolonged immunization.", "content": "Antigenic analysis of raw soybean: variation of host response during prolonged immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208699"} {"pmid": "4208700", "title": "Purification and characteristics of pyocin B39. I. General properties.", "content": "Purification and characteristics of pyocin B39. I. General properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208700"} {"pmid": "4208701", "title": "Isolation of Toxoplasma during unsuccessful attempts to isolate Rickettsiae from swine and rodents in Taiwan.", "content": "Isolation of Toxoplasma during unsuccessful attempts to isolate Rickettsiae from swine and rodents in Taiwan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208701"} {"pmid": "4208702", "title": "Bacterial meningitis: current status of vaccines against the meningococcus and hemophilus influenzae type B.", "content": "Bacterial meningitis: current status of vaccines against the meningococcus and hemophilus influenzae type B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208702"} {"pmid": "4208703", "title": "A review of brucellosis in the horse.", "content": "A review of brucellosis in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208703"} {"pmid": "4208704", "title": "Editorial: Diet and diverticular disease.", "content": "Editorial: Diet and diverticular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208704"} {"pmid": "4208705", "title": "Collaborative study of the determination of polychlorinated biphenyls in paperboard.", "content": "Collaborative study of the determination of polychlorinated biphenyls in paperboard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208705"} {"pmid": "4208706", "title": "Manual microbiological turbidimetric analysis of chlortetracycline in feeds.", "content": "Manual microbiological turbidimetric analysis of chlortetracycline in feeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208706"} {"pmid": "4208707", "title": "Direct chromatography of some N-methylcarbamate pesticides.", "content": "Direct chromatography of some N-methylcarbamate pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208707"} {"pmid": "4208708", "title": "Confirmation of pesticide residue identity. VII. Solid matrix derivation procedure for the simultaneous confirmation of heptachlor and endrin residues in the presence of large quantities of polychlorinated biphenyls.", "content": "Confirmation of pesticide residue identity. VII. Solid matrix derivation procedure for the simultaneous confirmation of heptachlor and endrin residues in the presence of large quantities of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208708"} {"pmid": "4208709", "title": "Colorimetric method for estimation of carbaryl and its residues on grains.", "content": "Colorimetric method for estimation of carbaryl and its residues on grains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208709"} {"pmid": "4208710", "title": "Determination of carbaryl in pesticide formulations and fertilizers by high-pressure liquid chromatography.", "content": "Determination of carbaryl in pesticide formulations and fertilizers by high-pressure liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208710"} {"pmid": "4208711", "title": "Human leukemia cell antigens: serologic characterization with xenoantisera.", "content": "Human leukemia cell antigens: serologic characterization with xenoantisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208711"} {"pmid": "4208713", "title": "Differential analysis of cyclocytidine, 1-beta-D-arabinofuranosylcytosine, and 1-beta-D-arabinofuranosyluracil by ultraviolet spectophotometry.", "content": "Differential analysis of cyclocytidine, 1-beta-D-arabinofuranosylcytosine, and 1-beta-D-arabinofuranosyluracil by ultraviolet spectophotometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208713"} {"pmid": "4208712", "title": "Human leukemia antigens: partial isolation and characterization.", "content": "Human leukemia antigens: partial isolation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208712"} {"pmid": "4208714", "title": "Effect of Brucella abortus infection (vaccine strain 19BA) on Rauscher leukemia virus and L1210 leukemia in mice.", "content": "Effect of Brucella abortus infection (vaccine strain 19BA) on Rauscher leukemia virus and L1210 leukemia in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208714"} {"pmid": "4208715", "title": "Effect of oral contraceptives on the mammary glands of Rhesus monkeys: a preliminary report.", "content": "Effect of oral contraceptives on the mammary glands of Rhesus monkeys: a preliminary report. To determine the relationship of oral contraceptive use and breast cancer, 96 rhesus monkeys were administered either Enovid-E (2.5 mg norethynodrel and .1 mg mestranol) or Ovulen (1 mg ethynodiol diacetate and .1 mg mestranol) cyclically for 5 years at doses of 1, 10 and 50 times the human dose. The animals' progress was compared with a control group of 32 monkeys. General physical and mammary gland examinations were conducted before treatment and monthly thereafter. During the 5 year study period none of the treated animals demonstrated clinical evidence of mammary gland lesions, no deaths from breast malignancy occurred, and no palpable breast nodules were found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208715"} {"pmid": "4208716", "title": "The problem of the alcohol-dependent individual.", "content": "The problem of the alcohol-dependent individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208716"} {"pmid": "4208717", "title": "Editorial: Plastic surgical treatment of basal cell skin cancer.", "content": "Editorial: Plastic surgical treatment of basal cell skin cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208717"} {"pmid": "4208718", "title": "Improved therapy for Vietnam acquired vivax malaria.", "content": "Improved therapy for Vietnam acquired vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208718"} {"pmid": "4208720", "title": "Host factors in human frostbite.", "content": "Host factors in human frostbite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208720"} {"pmid": "4208719", "title": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamá and Colombia. V. Arbovirus infection in non-human vertebrates.", "content": "A survey to assess potential human disease hazards along proposed sea level canal routes in Panamá and Colombia. V. Arbovirus infection in non-human vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208719"} {"pmid": "4208721", "title": "Serum uric acid and cholesterol variability for men aboard a Polaris submarine.", "content": "Serum uric acid and cholesterol variability for men aboard a Polaris submarine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208721"} {"pmid": "4208722", "title": "Medical evacuations for selected chronic diseases: USARPAC, 1970-71.", "content": "Medical evacuations for selected chronic diseases: USARPAC, 1970-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208722"} {"pmid": "4208723", "title": "The effect of premedication and angiography on arterial blood gases.", "content": "The effect of premedication and angiography on arterial blood gases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208723"} {"pmid": "4208724", "title": "Meningococcemia presenting as septic arthritis: case report.", "content": "Meningococcemia presenting as septic arthritis: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208724"} {"pmid": "4208725", "title": "Cerebral vasospasm: a review.", "content": "Cerebral vasospasm: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208725"} {"pmid": "4208726", "title": "The Alcohol Rehabilitation Unit, National Naval Medical Center, Bethesda.", "content": "The Alcohol Rehabilitation Unit, National Naval Medical Center, Bethesda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208726"} {"pmid": "4208739", "title": "Preparation of mono-specific antisera against staphylococcal alpha- and beta-hemolysin by using agar gel precipitates as immunogen.", "content": "Preparation of mono-specific antisera against staphylococcal alpha- and beta-hemolysin by using agar gel precipitates as immunogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208739"} {"pmid": "4208740", "title": "Reserpine in experimental cerebral edema: further observations.", "content": "Reserpine in experimental cerebral edema: further observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208740"} {"pmid": "4208742", "title": "Recurrent pneumomediastinum in diabetic ketoacidosis.", "content": "Recurrent pneumomediastinum in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208742"} {"pmid": "4208741", "title": "Pesticide residues in total diet samples. VI.", "content": "Pesticide residues in total diet samples. VI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208741"} {"pmid": "4208743", "title": "Letter: Anticonvulsant therapy in cerebral injuries.", "content": "Letter: Anticonvulsant therapy in cerebral injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208743"} {"pmid": "4208745", "title": "Temporally-related stimulus properties of delta9-tetrahydrocannabinol in monkeys.", "content": "Temporally-related stimulus properties of delta9-tetrahydrocannabinol in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208745"} {"pmid": "4208747", "title": "Intrathoracic vagus nerve tumours.", "content": "Intrathoracic vagus nerve tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208747"} {"pmid": "4208748", "title": "The identification of rumen ciliates from eastern Bos taurus.", "content": "The identification of rumen ciliates from eastern Bos taurus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208748"} {"pmid": "4208749", "title": "Histocompatibility-linked immune-response genes in the rhesus monkey.", "content": "Histocompatibility-linked immune-response genes in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208749"} {"pmid": "4208751", "title": "Further studies of tissue-typing sera in baboons.", "content": "Further studies of tissue-typing sera in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208751"} {"pmid": "4208750", "title": "Beneficial influence of limited histocompatibility of bone marrow grafted to unrelated rhesus monkeys preconditioned with x-ray and ALS.", "content": "Beneficial influence of limited histocompatibility of bone marrow grafted to unrelated rhesus monkeys preconditioned with x-ray and ALS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208750"} {"pmid": "4208753", "title": "Further studies with HL-A reagents raised in primates: analysis of the human HL-A2-HL-A28 cross-reaction.", "content": "Further studies with HL-A reagents raised in primates: analysis of the human HL-A2-HL-A28 cross-reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208753"} {"pmid": "4208752", "title": "Isolation of baboon xenogeneic histocompatibility antigens.", "content": "Isolation of baboon xenogeneic histocompatibility antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208752"} {"pmid": "4208754", "title": "Characterization of lymphocyte subpopulations of nonhuman primates separated by free-flow electrophoresis.", "content": "Characterization of lymphocyte subpopulations of nonhuman primates separated by free-flow electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208754"} {"pmid": "4208755", "title": "Use of nonhuman primates for assaying tumorigenicity of viral-vaccine cell substrates.", "content": "Use of nonhuman primates for assaying tumorigenicity of viral-vaccine cell substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208755"} {"pmid": "4208756", "title": "Immunopathogenesis of dengue infection in the rhesus monkey.", "content": "Immunopathogenesis of dengue infection in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208756"} {"pmid": "4208757", "title": "Transfer of delayed hypersensitivity to nonsensitive human leukocytes with rhesus-monkey lymphoid RNA extracts.", "content": "Transfer of delayed hypersensitivity to nonsensitive human leukocytes with rhesus-monkey lymphoid RNA extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208757"} {"pmid": "4208758", "title": "Studies on rhesus-monkey nondialyzable and dialyzable transfer factors.", "content": "Studies on rhesus-monkey nondialyzable and dialyzable transfer factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208758"} {"pmid": "4208763", "title": "Isolation of Theileria mutans from cattle in Essex.", "content": "Isolation of Theileria mutans from cattle in Essex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208763"} {"pmid": "4208764", "title": "Lassa fever and Marburg virus disease.", "content": "Lassa fever and Marburg virus disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208764"} {"pmid": "4208768", "title": "Effect of barometric pressure change on the ear following stapedectomy.", "content": "Effect of barometric pressure change on the ear following stapedectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208768"} {"pmid": "4208770", "title": "Heat stability of the precipitin reactants in normal chicken sera.", "content": "Heat stability of the precipitin reactants in normal chicken sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208770"} {"pmid": "4208769", "title": "Genetic control of urea resistant esterase of liver extracts in chicken.", "content": "Genetic control of urea resistant esterase of liver extracts in chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208769"} {"pmid": "4208772", "title": "Protein-bound sulfhydryl groups and thiolesters in mitochondria and submitochondrial particles and their relationships to oxidative phosphorylation.", "content": "Protein-bound sulfhydryl groups and thiolesters in mitochondria and submitochondrial particles and their relationships to oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208772"} {"pmid": "4208771", "title": "Studies on the mechanism of action of nalidixic acid.", "content": "Studies on the mechanism of action of nalidixic acid. With three independent techniques (absorption spectrophotometry, measurement of the deoxyribonucleic acid [DNA] melting temperature, and equilibrium dialysis), no evidence has been found for the binding of nalidixic acid to purified DNA. Also, no evidence has been found to support the hypothesis that nalidixic acid is permanently modified to a new, active compound by the bacterial cell. By using an in vitro DNA replication system developed by Bonhoeffer and colleagues, soluble extracts from nalidixic acid-sensitive cells have been shown to confer nalidixic acid sensitivity on the DNA synthesis of lysates from nalidixic acid-resistant cells. The activity in the extracts is only present in sensitive cells and is nondialyzable and heat sensitive. Finally, two known nalidixic acid-resistant mutants of Escherichia coli, mapping at nal A and nal B, respectively, have been tested to determine whether either of them is a transport mutant. It has been shown that nal B(r) is a transport mutant whereas nal A(r) is not.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208771"} {"pmid": "4208773", "title": "Interaction of spinach leaf adenosine diphosphate glucose alpha-1,4-glucan alpha-4-glucosyl transferase and alpha-1,4-glucan, alpha-1,4-glucan-6-glycosyl transferase in synthesis of branched alpha-glucan.", "content": "Interaction of spinach leaf adenosine diphosphate glucose alpha-1,4-glucan alpha-4-glucosyl transferase and alpha-1,4-glucan, alpha-1,4-glucan-6-glycosyl transferase in synthesis of branched alpha-glucan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208773"} {"pmid": "4208774", "title": "Bacillus licheniformis 749-C plasma membrane penicillinase, a hydrophobic polar protein.", "content": "Bacillus licheniformis 749-C plasma membrane penicillinase, a hydrophobic polar protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208774"} {"pmid": "4208775", "title": "Studies on spinach leaf ribulosebisphosphate carboxylase. Carboxylase and oxygenase reaction examined by immunochemical methods.", "content": "Studies on spinach leaf ribulosebisphosphate carboxylase. Carboxylase and oxygenase reaction examined by immunochemical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208775"} {"pmid": "4208776", "title": "Purification and properties of T2 bacteriophage-induced thymidylate synthetase.", "content": "Purification and properties of T2 bacteriophage-induced thymidylate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208776"} {"pmid": "4208777", "title": "Purification of rat urinary kallikreins and their specific antibody.", "content": "Purification of rat urinary kallikreins and their specific antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208777"} {"pmid": "4208778", "title": "Topography of ribosomal proteins of the Escherichia coli 30S subunit as studied with the reversible cross-linking reagent methyl 4-mercaptobutyrimidate.", "content": "Topography of ribosomal proteins of the Escherichia coli 30S subunit as studied with the reversible cross-linking reagent methyl 4-mercaptobutyrimidate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208778"} {"pmid": "4208779", "title": "Platelet satellitism.", "content": "Platelet satellitism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208779"} {"pmid": "4208780", "title": "Responsiveness of human granulocytic leukemic cells to colony-stimulating factor.", "content": "Responsiveness of human granulocytic leukemic cells to colony-stimulating factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208780"} {"pmid": "4208782", "title": "The synaptinemal complex in homologous and nonhomologous pairing of chromosomes.", "content": "The synaptinemal complex in homologous and nonhomologous pairing of chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208782"} {"pmid": "4208783", "title": "One the nature of chromosome-sized DNA molecules.", "content": "One the nature of chromosome-sized DNA molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208783"} {"pmid": "4208784", "title": "The units of DNA replication in Drosophila melanogaster chromosomes.", "content": "The units of DNA replication in Drosophila melanogaster chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208784"} {"pmid": "4208785", "title": "Organization and transcription of DNA in chromosomes and mitochondria of Drosophila.", "content": "Organization and transcription of DNA in chromosomes and mitochondria of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208785"} {"pmid": "4208786", "title": "Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA.", "content": "Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208786"} {"pmid": "4208787", "title": "Bulk isolation of metaphase chromosomes from an in vitro cell line of Drosophila melanogaster.", "content": "Bulk isolation of metaphase chromosomes from an in vitro cell line of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208787"} {"pmid": "4208788", "title": "Repetitive sequences in isolated Thomas circles from Drosophila melanogaster.", "content": "Repetitive sequences in isolated Thomas circles from Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208788"} {"pmid": "4208789", "title": "Repetitive DNA in polytene chromosomes of Drosophila melanogaster.", "content": "Repetitive DNA in polytene chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208789"} {"pmid": "4208791", "title": "Unequal mitotic sister chromatid exchange and disproportionate replication as mechanisms regulating ribosomal RNA gene redundancy.", "content": "Unequal mitotic sister chromatid exchange and disproportionate replication as mechanisms regulating ribosomal RNA gene redundancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208791"} {"pmid": "4208790", "title": "Studies on the transfer RNA genes of Drosophila.", "content": "Studies on the transfer RNA genes of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208790"} {"pmid": "4208792", "title": "An examination of the one cistron: one chromomere concept.", "content": "An examination of the one cistron: one chromomere concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208792"} {"pmid": "4208793", "title": "Analysis of a whole chromosome in Drosophila.", "content": "Analysis of a whole chromosome in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208793"} {"pmid": "4208794", "title": "The one band-one gene hypothesis: evidence from a cytogenetic analysis of mutant and nonmutant rearrangement breadpoints in Drosophila melanogaster.", "content": "The one band-one gene hypothesis: evidence from a cytogenetic analysis of mutant and nonmutant rearrangement breadpoints in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208794"} {"pmid": "4208795", "title": "Organization of chromomeres.", "content": "Organization of chromomeres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208795"} {"pmid": "4208796", "title": "Chromosome structure in ciliated protozoans.", "content": "Chromosome structure in ciliated protozoans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208796"} {"pmid": "4208797", "title": "Temporal control of puffing activity in polytene chromosomes.", "content": "Temporal control of puffing activity in polytene chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208797"} {"pmid": "4208798", "title": "Transcription and chromatin structure.", "content": "Transcription and chromatin structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208798"} {"pmid": "4208799", "title": "Ultrastructure of active eukaryotic genomes.", "content": "Ultrastructure of active eukaryotic genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208799"} {"pmid": "4208801", "title": "Experimental glaucoma in the rhesus monkey.", "content": "Experimental glaucoma in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208801"} {"pmid": "4208802", "title": "Lenticular and fundus changes induced by the intraocular infusion of sodium aspartate.", "content": "Lenticular and fundus changes induced by the intraocular infusion of sodium aspartate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208802"} {"pmid": "4208803", "title": "Some enzymic properties of human lens esterase I.", "content": "Some enzymic properties of human lens esterase I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208803"} {"pmid": "4208804", "title": "Intraocular pressure following long posterior ciliary canal cautery in primates.", "content": "Intraocular pressure following long posterior ciliary canal cautery in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208804"} {"pmid": "4208805", "title": "The nature of chorioretinal lesions produced by the gallium arsenide laser.", "content": "The nature of chorioretinal lesions produced by the gallium arsenide laser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208805"} {"pmid": "4208806", "title": "Transient lack of thyrotropin (TSH) response to thyrotropin-releasing hormone (TRH) in treated hyperthyroid patients with normal or low serum thyroxine (T4) and triiodothyronine (T3).", "content": "Transient lack of thyrotropin (TSH) response to thyrotropin-releasing hormone (TRH) in treated hyperthyroid patients with normal or low serum thyroxine (T4) and triiodothyronine (T3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208806"} {"pmid": "4208807", "title": "Serum growth hormone and prolactin response to thyrotropin-releasing hormone in patients with acromegaly before and after surgery.", "content": "Serum growth hormone and prolactin response to thyrotropin-releasing hormone in patients with acromegaly before and after surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208807"} {"pmid": "4208808", "title": "Parathyroid function in patients with hyper- or hypothyroidism.", "content": "Parathyroid function in patients with hyper- or hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208808"} {"pmid": "4208809", "title": "Recovery of function: a review of studies pertaining to the serial lesion procedure and brain damage in infancy.", "content": "Recovery of function: a review of studies pertaining to the serial lesion procedure and brain damage in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208809"} {"pmid": "4208810", "title": "Letter: Effect of Rev 1 vaccination.", "content": "Letter: Effect of Rev 1 vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208810"} {"pmid": "4208811", "title": "Assessment of bowel viability using 99Mtechnetium-tagged albumin microspheres.", "content": "Assessment of bowel viability using 99Mtechnetium-tagged albumin microspheres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208811"} {"pmid": "4208812", "title": "Experimental evaluation of the \"gastric barrier\" in CSF shunt infections.", "content": "Experimental evaluation of the \"gastric barrier\" in CSF shunt infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208812"} {"pmid": "4208813", "title": "The study of bile salt kinetics in the experimental animal using a new technique.", "content": "The study of bile salt kinetics in the experimental animal using a new technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208813"} {"pmid": "4208816", "title": "Spontaneous diabetes in monkeys.", "content": "Spontaneous diabetes in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208816"} {"pmid": "4208815", "title": "Histopathology of the myocardium in 50 apparently healthy cats.", "content": "Histopathology of the myocardium in 50 apparently healthy cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208815"} {"pmid": "4208817", "title": "Clinical assessment of reproductive function in female rhesus monkeys: individual physical examination.", "content": "Clinical assessment of reproductive function in female rhesus monkeys: individual physical examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208817"} {"pmid": "4208828", "title": "Lethal trait A 46 in cattle. Immunological investigations.", "content": "Lethal trait A 46 in cattle. Immunological investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208828"} {"pmid": "4208829", "title": "Editorial: Drugs in asthma.", "content": "Editorial: Drugs in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208829"} {"pmid": "4208830", "title": "The changing role of occupational therapy.", "content": "The changing role of occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208830"} {"pmid": "4208831", "title": "Characterization of salivary proteins in patients with Sjögren's syndrome.", "content": "Characterization of salivary proteins in patients with Sjögren's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208831"} {"pmid": "4208833", "title": "Micromelic type of spondylo-meta-epiphyseal dysplasia.", "content": "Micromelic type of spondylo-meta-epiphyseal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208833"} {"pmid": "4208832", "title": "Biologic effects of dental materials. 3. Toxicity and antimicrobial effect of endodontic antiseptics in vitro.", "content": "Biologic effects of dental materials. 3. Toxicity and antimicrobial effect of endodontic antiseptics in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208832"} {"pmid": "4208835", "title": "The effect of products D and E on the thrombin induced conversion of fibrinogen to fibrin.", "content": "The effect of products D and E on the thrombin induced conversion of fibrinogen to fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208835"} {"pmid": "4208834", "title": "IgG subclasses: relationship to clinical aspects of multiple myeloma and frequency distribution among M-components.", "content": "IgG subclasses: relationship to clinical aspects of multiple myeloma and frequency distribution among M-components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208834"} {"pmid": "4208837", "title": "Fine structure of rat incisor ameloblasts in transition between enamel secretion and maturation stages.", "content": "Fine structure of rat incisor ameloblasts in transition between enamel secretion and maturation stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208837"} {"pmid": "4208836", "title": "Red-cell carbonic anhydrase isoenyzmes in megaloblastic anaemia.", "content": "Red-cell carbonic anhydrase isoenyzmes in megaloblastic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208836"} {"pmid": "4208838", "title": "Characteristics of a nucleoproteinaceous subviral entity resulting from partial degradation of southern bean mosaic virus.", "content": "Characteristics of a nucleoproteinaceous subviral entity resulting from partial degradation of southern bean mosaic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208838"} {"pmid": "4208839", "title": "F116, D3 and G101: temperate bacteriophages of Pseudomonas aeruginosa.", "content": "F116, D3 and G101: temperate bacteriophages of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208839"} {"pmid": "4208840", "title": "effects of aldehyde fixation and of preganglionic denervation on acetylcholinesterase and butyrocholinesterase of cat autonomic ganglia.", "content": "effects of aldehyde fixation and of preganglionic denervation on acetylcholinesterase and butyrocholinesterase of cat autonomic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208840"} {"pmid": "4208841", "title": "Squirrel monkey platform runway test. A preliminary report.", "content": "Squirrel monkey platform runway test. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208841"} {"pmid": "4208843", "title": "The switch point in mu heavy chains of human IgM immunoglobulins.", "content": "The switch point in mu heavy chains of human IgM immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208843"} {"pmid": "4208842", "title": "Hydrogen-tritium exchange in polypeptides. Models of alpha-helical and beta conformations.", "content": "Hydrogen-tritium exchange in polypeptides. Models of alpha-helical and beta conformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208842"} {"pmid": "4208844", "title": "Isolation and properties of the principal liver protein conjugate of a hepatic carcinogen.", "content": "Isolation and properties of the principal liver protein conjugate of a hepatic carcinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208844"} {"pmid": "4208845", "title": "Kinetics of interaction of cyanate ion with cobalt bovine carbonic anhydrase.", "content": "Kinetics of interaction of cyanate ion with cobalt bovine carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208845"} {"pmid": "4208846", "title": "Characterization of an additional protein in pancreatic juice of men with chronic calcifying pancreatitis. Identification to lactoferrin.", "content": "Characterization of an additional protein in pancreatic juice of men with chronic calcifying pancreatitis. Identification to lactoferrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208846"} {"pmid": "4208848", "title": "Anterior pharyngeal pouch.", "content": "Anterior pharyngeal pouch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208848"} {"pmid": "4208849", "title": "Three unusual foreign bodies.", "content": "Three unusual foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208849"} {"pmid": "4208850", "title": "Microtubules and movement in the archigregarine, Selenidium fallax.", "content": "Microtubules and movement in the archigregarine, Selenidium fallax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208850"} {"pmid": "4208851", "title": "The purification and properties of a ribonuclease of the roe of the scallop Chlamys opercularis.", "content": "The purification and properties of a ribonuclease of the roe of the scallop Chlamys opercularis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208851"} {"pmid": "4208852", "title": "Protein synthesis in a cell-free preparation from rumen Protozoa.", "content": "Protein synthesis in a cell-free preparation from rumen Protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208852"} {"pmid": "4208853", "title": "Angiokeratoma corporis diffusum (Fabry's diseases).", "content": "Angiokeratoma corporis diffusum (Fabry's diseases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208853"} {"pmid": "4208854", "title": "Human pancreatic proteolytic enzymes and protein inhibitors. Isolation and molecular properties.", "content": "Human pancreatic proteolytic enzymes and protein inhibitors. Isolation and molecular properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208854"} {"pmid": "4208847", "title": "Can Aspergillus flavus cause maduromycetoma?", "content": "Can Aspergillus flavus cause maduromycetoma?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208847"} {"pmid": "4208855", "title": "Selection for reduced crossing over in Drosophila melanogaster.", "content": "Selection for reduced crossing over in Drosophila melanogaster. Selection was practiced for reducing crossing over between the third chromosome genes Sb and H(2) of Drosophila melanogaster; the method employed was to select the repulsion double heterozygotes Sb+/+H(2) every generation. Two replicate selection lines were maintained. After 24 generations of selection, Line 1 showed no significant difference from the control, although the regression of recombination value on generation was significant. In generation 20, Line 2 had a significantly lower recombination value than the control, as well as having a highly significant regression coefficient. No chromosome rearrangements were involved in the response. It was concluded that there was substantial genic variability in the frequency of crossing over between Sb and H(2) in the base population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208855"} {"pmid": "4208856", "title": "On recombination-defective meiotic mutants in Drosophila melanogaster.", "content": "On recombination-defective meiotic mutants in Drosophila melanogaster. The genetic effects of four recombination-defective meiotic mutants in D. melanogaster on recombination, segregation and the relationship between the two have been examined. The results suggest the following. (1) The anomalous meiotic segregation observed in females carrying recombination-defective meiotic mutants is a normal consequence of the reduction in exchange; each recombination-defective mutant can, therefore, be defined by a single lesion in the control of recombination. (2) Of the operations used to date to characterize this lesion, the most informative is whether the decrease in recombination is uniform along the chromosome arm or nonuniform; in particular, if the formation of recombinants is visualized as a two-step process consisting of the establishment of possible exchange points (exchange preconditions) followed by exchange itself, then mutants that uniformly decrease crossing over involve defects in the second step while mutants that result in a nonuniform decrease involve defects in the establishment of exchange preconditions. (3) Of the fourteen loci identified by recombination-defective meiotic mutants, only one (with two alleles) is involved in exchange itself; the others all reduce recombination most drastically in distal regions, suggesting that the establishment of exchange preconditions involves polar processes. (4) A very general description of the polar establishment of exchange preconditions is presented; this description has the property that if a precondition meiotic mutant affects interference, the coefficient of coincidence will be increased in proportion to the decrease in recombination which is what is observed for all recombination-defective meiotic mutants studied to date.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208856"} {"pmid": "4208857", "title": "Genetic dissection of segregation distortion. I. Suicide combinations of SD genes.", "content": "Genetic dissection of segregation distortion. I. Suicide combinations of SD genes. Two major loci in the Tft-cn region of an SD chromosome have been separated by recombination and identified. The allele at the left-hand locus on an SD chromosome is called Sd; the allele at the right-hand locus is called Rsp. Both Sd and Rsp are necessary to bring about a distortion of the segregation ratio in heterozygous SD males, although the particular degree of distortion exhibited by an SD chromosome is influenced by the constellation of polygenic modifiers of SD in the genome. The coupling phase of the alleles, Sd Rsp/Sd(+)Rsp(+), produces about 89-90% of Sd Resp-bearing progeny. The repulsion phase, Sd Rsp(+)/Sd(+)Rsp, produces 10-20% of Sd Rsp(+)-bearing progeny. No coupling-repulsion effects between Sd and Rsp are apparent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208857"} {"pmid": "4208859", "title": "A cold-sensitive zygotic lethal causing high frequencies of nondisjunction during meiosis I in Drosophila melanogaster females.", "content": "A cold-sensitive zygotic lethal causing high frequencies of nondisjunction during meiosis I in Drosophila melanogaster females. The X-linked, cold-sensitive zygotic lethal, l(1)TW-6(cs), both in homozygous and heterozygous females, induces nondisjunction of all four chromosomes at Meiosis I at both 25 degrees and 17 degrees . Nondisjunction frequencies approaching 0.5 for the X and fourth chromosomes have been observed at 16 degrees -18 degrees . The disjunction of the X chromosomes in males is not affected. The mutant causes mitotic irregularities in zygotes at both 25 degrees and 17 degrees . Mortality of all zygotes produced by the crosses 6(cs)/6(cs)x6(cs)/B(s)Y and FM7/6(cs)x6(cs)/B(s)Y is respectively 86% and 67-74% at 25 degrees and 99.8-99.9% and 94% at 17 degrees . The mortality of 6(cs) hemizygotes derived from females carrying no doses of 6(cs) (C(1)DX,y f/yx6(cs)/B(s)Y) is 45-55% at 25 degrees and 98% at 17 degrees . The length of the temperature-sensitive period for 6(cs) homo- and hemizygotes is affected by the maternal dosage of 6(cs); the shortest TSP is for zero and the longest is for two maternal doses. Mortality takes place primarily during embryogenesis with some larval and little pupal mortality. Analysis of sectioned embryos indicates that the large array of different patterns of damage observed could have arisen from abnormal cleavage divisions and the incomplete population of the blastoderm with nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208859"} {"pmid": "4208858", "title": "The developmental genetics of the temperature sensitive lethal allele of the suppressor of forked, 1(1)su(f)ts67g, in Drosophila melanogaster.", "content": "The developmental genetics of the temperature sensitive lethal allele of the suppressor of forked, 1(1)su(f)ts67g, in Drosophila melanogaster. A temperature-sensitive lethal allele of suppressor of forked, l(1)su(f)(ts67g) (ts67), has been discovered and characterized as follows: Flies which are hemizygous for ts67 live at 18 degrees and 25 degrees but die at 30 degrees primarily as larvae. The temperature-sensitive period for ts67 homozygotes or hemizygotes begins in second instar and ends at pupation. ts67 is lethal at 30 degrees when heterozygous with suppressor of forked (su(f)), a deficiency for suppressor of forked (su(f)(-)), and a non-conditional lethal allele of suppressor of forked (3DES). It is viable at 30 degrees when heterozygous with the wild-type allele of suppressor of forked. At 25 degrees but not at 18 degrees forked bristles are suppressed in flies of the following genotypes: f(s)ts67/Y, f(s)ts67/f(s)ts67, f(s)ts67/f(s)su(f), f(u)ts67/f(s)3DES, f(u)ts67/f(s)su(f)(-), f(u)ts67/f(s)su(f). There is some suppression of forked bristles at 25 degrees in the heterozygote, f(s)ts67/f(s)+(su(f)). The forked bristle phenotype is not suppressed at either temperature in flies of the genotypes f(u)ts67/Y, f(u)ts67/f(u)ts67/ (f(s) and f(u) indicating suppressible and unsuppressible alleles of forked). The temperature-sensitive period for suppression of forked bristles begins at pupation and extends through the period of bristle synthesis. The deficiency phenotype (bristles reduced in size or absent, wing wrinkled or blistered, eyes rough) typical of flies of the genotype f(s)su(f)/f(s)su(f)(-) at 18 degrees and 25 degrees , is exhibited by flies of the genotypes f(s)ts67/f(s)su(f)(-) at 25 degrees and f(u)ts67/f(s)su(f) at 29 degrees . An allele of lozenge (lz(1)) which can be suppressed by su(f) is suppressed at 25 degrees but not at 18 degrees in lz(1)ts67/Y males. ts67 homozygous females are fertile at 25 degrees but sterile at 30 degrees . The hypothesis is discussed that the su(f) locus codes for a ribosomal protein and that suppression and enhancement are affected by mutations at the locus by mutant ribosome-induced misreading. The possibility is presented that ts67 may be used to determine the translation time in development of any gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208858"} {"pmid": "4208860", "title": "The effects of r- and K-selection on components of variance for two quantitative traits.", "content": "The effects of r- and K-selection on components of variance for two quantitative traits. The genetic and environmental components of variance for two quantitative characters were measured in the descendants of Drosophila melanogaster populations which had been grown for several generations at densities of 100, 200, 300, and 400 eggs per vial. Populations subject to intermediate densities had a greater proportion of phenotypic variance available for selection than populations from either extreme. Selection on either character would be least effective under pure r-selection, a frequent attribute of selection programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208860"} {"pmid": "4208861", "title": "The distribution of mucins in the nasopharynx of some primates.", "content": "The distribution of mucins in the nasopharynx of some primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208861"} {"pmid": "4208862", "title": "Development of the secondary interstitial gland in the rabbit ovary.", "content": "Development of the secondary interstitial gland in the rabbit ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208862"} {"pmid": "4208863", "title": "Proceedings: The pharyngeal hypophysis in the laboratory animal.", "content": "Proceedings: The pharyngeal hypophysis in the laboratory animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208863"} {"pmid": "4208864", "title": "Proceedings: Immunoglobulin in pig salivary gland homogenates.", "content": "Proceedings: Immunoglobulin in pig salivary gland homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208864"} {"pmid": "4208865", "title": "Proceedings: Gene frequency variation in Kenya baboon populations.", "content": "Proceedings: Gene frequency variation in Kenya baboon populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208865"} {"pmid": "4208866", "title": "Hearing in the owl monkey (Aotus trivirgatus). I. Auditory sensitivity.", "content": "Hearing in the owl monkey (Aotus trivirgatus). I. Auditory sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208866"} {"pmid": "4208867", "title": "Thermal thresholds of the rhesus monkey (Macaca mulatta).", "content": "Thermal thresholds of the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208867"} {"pmid": "4208868", "title": "Ovarian hormones and sexual behavior in Macaca Nemestrina.", "content": "Ovarian hormones and sexual behavior in Macaca Nemestrina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208868"} {"pmid": "4208869", "title": "The effect of enzymes on structural and biological properties of Semliki forest virus.", "content": "The effect of enzymes on structural and biological properties of Semliki forest virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208869"} {"pmid": "4208870", "title": "Effect of fragmentation on interferon induction by double-stranded virus RNA.", "content": "Effect of fragmentation on interferon induction by double-stranded virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208870"} {"pmid": "4208871", "title": "Tissue fixation with diimidoesters as an alternative to aldehydes. I. Comparison of cross-linking and ultrastructure obtained with dimethylsuberimidate and glutaraldehyde.", "content": "Tissue fixation with diimidoesters as an alternative to aldehydes. I. Comparison of cross-linking and ultrastructure obtained with dimethylsuberimidate and glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208871"} {"pmid": "4208872", "title": "Amodioquine induced oral pigmentation--a light and electron microscopic study.", "content": "Amodioquine induced oral pigmentation--a light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208872"} {"pmid": "4208873", "title": "The effects of bacterial plaque extracts on organ cultures of fetal rat masticatory mucosa. I. Histochemistry.", "content": "The effects of bacterial plaque extracts on organ cultures of fetal rat masticatory mucosa. I. Histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208873"} {"pmid": "4208874", "title": "The effects of bacterial plaque extracts on organ cultures of fetal rat masticatory mucosa. II. Electron microscopy.", "content": "The effects of bacterial plaque extracts on organ cultures of fetal rat masticatory mucosa. II. Electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208874"} {"pmid": "4208875", "title": "The crypt surface of blade-vent implants in clinical failure: an electron microscopic study.", "content": "The crypt surface of blade-vent implants in clinical failure: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208875"} {"pmid": "4208879", "title": "Translation of Pseudomonas aeruginosa bacteriophage PP7 RNA by a cell-free amino acid incorporating system from Escherichia coli.", "content": "Translation of Pseudomonas aeruginosa bacteriophage PP7 RNA by a cell-free amino acid incorporating system from Escherichia coli. We have compared the activities of the RNA genomes of Pseudomonas aeruginosa phage PP7 and coliphages Qbeta and f2 in a cell-free amino acid incorporating system derived from Escherichia coli. The rate of incorporation of [(14)C]leucine in the PP7 RNA-directed system is greater than in the systems directed by either Qbeta or f2 RNA. The response to changes in phage RNA concentrations is similar in all the systems, reaching a saturation level at 0.75 to 1.0 mg of RNA per ml of reaction mixture. Analysis of complete reaction mixtures of the PP7 RNA and of the Qbeta RNA systems by sucrose gradient centrifugation shows generally similar patterns for both RNAs. The principal differences are that in the PP7 system a slightly higher percentage of RNA forms ribosome complexes and that the polysomes are somewhat smaller. PP7 RNA is also degraded more extensively during the reaction than is Qbeta RNA. Analysis of the products of the reactions by acrylamide gel electrophoresis shows that PP7 coat protein is the only identifiable product of the PP7 RNA-directed system, suggesting that only the coat protein cistron is translated by E. coli ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208879"} {"pmid": "4208880", "title": "Ribosomal protein neighborhoods. 3. Cooperativity of assembly.", "content": "Ribosomal protein neighborhoods. 3. Cooperativity of assembly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208880"} {"pmid": "4208881", "title": "Strains of Bacillus subtilis synthesizing elevated levels of isoleucine-valine biosynthetic enzymes.", "content": "Strains of Bacillus subtilis synthesizing elevated levels of isoleucine-valine biosynthetic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208881"} {"pmid": "4208885", "title": "Differentiation of the contractile effects of prostaglandin E2 and the C-terminal octapeptide of cholecystokinin in isolated guinea-pig gallbladder.", "content": "Differentiation of the contractile effects of prostaglandin E2 and the C-terminal octapeptide of cholecystokinin in isolated guinea-pig gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208885"} {"pmid": "4208883", "title": "The demonstration of antibodies to Sarcocystis fusiformis antigen in sera of Isospora hominis carriers, using the indirect fluorescence technique.", "content": "The demonstration of antibodies to Sarcocystis fusiformis antigen in sera of Isospora hominis carriers, using the indirect fluorescence technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208883"} {"pmid": "4208884", "title": "Biliary excretion of some penicillins, quaternary ammonium compounds and tertiary amines, including aspects on mechanisms for their excretion.", "content": "Biliary excretion of some penicillins, quaternary ammonium compounds and tertiary amines, including aspects on mechanisms for their excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208884"} {"pmid": "4208886", "title": "The indirect immunoenzyme test for the detection of antibodies against North American Borreliae. I. Technic and results with sera of vervet monkeys (Cercopithecus aethiops).", "content": "The indirect immunoenzyme test for the detection of antibodies against North American Borreliae. I. Technic and results with sera of vervet monkeys (Cercopithecus aethiops).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208886"} {"pmid": "4208887", "title": "Efficacy of the Candida precipitin test. Verification with a protoplast antigen preparation.", "content": "Efficacy of the Candida precipitin test. Verification with a protoplast antigen preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208887"} {"pmid": "4208888", "title": "Rapid detection of bacteremia by a radiometric system. A clinical evaluation.", "content": "Rapid detection of bacteremia by a radiometric system. A clinical evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208888"} {"pmid": "4208889", "title": "Parenteral nutrition in seriously ill neonates. Search for the ideal mixture.", "content": "Parenteral nutrition in seriously ill neonates. Search for the ideal mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208889"} {"pmid": "4208890", "title": "Serum proteins in hepatosis of pregnancy and pre-eclampsia.", "content": "Serum proteins in hepatosis of pregnancy and pre-eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208890"} {"pmid": "4208891", "title": "Pigmenturia from conga drumming. Hemoglobinuria and myoglobinuria.", "content": "Pigmenturia from conga drumming. Hemoglobinuria and myoglobinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208891"} {"pmid": "4208892", "title": "Care of the aged: an English lesson?", "content": "Care of the aged: an English lesson?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208892"} {"pmid": "4208893", "title": "Editorial: How clinically useful is T and B cell quantitation?", "content": "Editorial: How clinically useful is T and B cell quantitation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208893"} {"pmid": "4208894", "title": "Autonomic drugs in ophthalmology: some problems and promises. I. Directly and indirectly acting parasympathomimetic drugs.", "content": "Autonomic drugs in ophthalmology: some problems and promises. I. Directly and indirectly acting parasympathomimetic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208894"} {"pmid": "4208895", "title": "Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.", "content": "Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. A new cephalosporin with a highly reactive beta-lactam ring was found to give an immediate color change in the presence of beta-lactamases from many bacteria, including staphylococci, Bacillus species, Enterobacteriaceae, and Pseudomonas. The reaction is confined to organisms producing beta-lactamases, but it is sufficiently sensitive to indicate the presence of this enzyme is small amounts in strains previously considered not to produce it. The compound has an unusual ultraviolet spectrum, and the color change can be followed quantitatively by measuring changes in absorption which occur in the 380- to 500-nm region, where cephalosporins normally have no absorption. The development of color is thought to be a consequence of the beta-lactam ring being unusually highly conjugated with the 3-substituent. Although in the bacteria only beta-lactamases produce this color change, it was found that serum and tissues from experimental animals also rapidly produced the colored breakdown product, which was then excreted in the urine. The mechanism of the mammalian breakdown was considered to be different from that found in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208895"} {"pmid": "4208896", "title": "Evaluation of a new cephalosporin antibiotic, cephapirin.", "content": "Evaluation of a new cephalosporin antibiotic, cephapirin. Cephapirin sodium, a parenterally administered derivative of cephalosporanic acid, was tested in vitro against 150 stock cultures of Enterobacteriaceae and 30 stock cultures each of Pseudomonas aeruginosa and Staphylococcus aureus. Both broth- and agar-dilution techniques were employed with two sizes of inocula of organisms. At a concentration of 7.5 mug or less/ml, cephapirin inhibited and killed 100% of strains of Escherichia coli and Proteus mirabilis and more than 80% of Klebsiella species when tested against an inoculum of 10(5) bacterial cells/ml. However, even at 100 mug/ml, only a few isolates of other Enterobacteriaceae and Pseudomonas were inhibited. A 100-fold increase in the inoculum resulted in decreased susceptibility of organisms. All penicillin-susceptible as well as penicillin-resistant S. aureus isolates were inhibited and killed by 5 mug or less of cephapirin/ml when tested with an inoculum of either 10(4) or 10(6) organisms/ml. The drug also was studied in various doses in the treatment of 77 patients with diverse infections. Cephapirin was effective in the treatment of 27 of 32 patients with pulmonary infection, as well as in 6 of 7 patients with staphylococcal or streptococcal soft tissue infection. Of 25 patients with urinary-tract infections, 19 developed a negative culture during therapy. A single 4-g intramuscular dose of cephapirin was effective in only 2 of 11 patients with gonococcal urethritis or endocervicitis. Two patients with gonococcal urethritis treated with multiple injections were cured. The drug was well tolerated except for pain at the site of injection in 14 patients and phlebitis in 4 patients. No abnormalities in renal or hepatic function could be attributed to cephapirin. In addition, no abnormalities were found in the renal tubules of rabbits challenged with 500 mg of cephapirin/kg. If further studies document that cephapirin is well tolerated by the parenteral route, it may have advantages over cephalothin or cephaloridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208896"} {"pmid": "4208897", "title": "Effect of exogenous penicillin on penicillin biosynthesis.", "content": "Effect of exogenous penicillin on penicillin biosynthesis. The addition of phenoxymethylpenicillin (10 mg/ml) at any time during the penicillin fermentation inhibited further accumulation of the antibiotic in broth but had no effect on growth. Benzylpenicillin, 6-aminopenicillanic acid (6-APA), and some semisynthetic penicillins also showed this effect, but penicillin N, penicilloic acid, cephalosporin C, and 7-aminocephalosporanic acid did not limit penicillin accretion. Incorporation of radioactive precursors (cysteine, valine, and sodium phenoxyacetate) into penicillin in the presence of inhibitory concentrations of the antibiotic indicated that penicillin synthesis continued despite the lack of accretion of the antibiotic in broth. The rates of penicillin synthesis in a 48-hr and a 136-hr culture were compared by short-term exposure to Na(2) (35)SO(4), and no significant difference in the biosynthetic rate was observed. Exogenous penicillin in the range of 1 to 15 mg/ml of culture broth had no effect on utilization of acetate or glucose by Penicillium chrysogenum. The antibiotic-synthesizing capacity of the organism was not irreversibly inhibited by exogenous penicillin. The degradation of penicillin during the fermentation was also studied. Penicillin V was stable in broth filtrate. Catabolic enzymes such as penicillinase and penicillin-acylase were not demonstrated in whole broth, nor was the accumulation of 6-APA, penicilloic acid, or other degradation products detected. An examination of the intracellular penicillin concentration and the amount of penicillin associated with the mycelium revealed that cells contained significantly more penicillin late in the fermentation than earlier in the cycle. This cell-associated antibiotic may be a regulatory factor in further penicillin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208897"} {"pmid": "4208898", "title": "Factors influencing the microbiological assay of tobramycin.", "content": "Factors influencing the microbiological assay of tobramycin. Tobramycin belongs to the aminoglycoside class of antibiotics. Assay procedures were investigated to determine the most suitable methods for the assay of tobramycin in blood, urine, and pharmaceutical preparations. The agar-plate assay was the method of choice for determinations in urine and serum. The turbidimetric assay was selected for the assay of pharmaceutical preparations. An extraction technique is described that minimizes problems encountered in the estimation of tobramycin in urine. Sample diluents, pH, and molarity were important and were variable depending on assay methods. Evidence is presented to show binding of tobramycin to alpha-cellulose susceptibility discs. Iron and sodium ions demonstrated potential inhibition of tobramycin in all assay methods tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208898"} {"pmid": "4208899", "title": "Effect of chemotherapeutic agents upon microorganisms isolated from cancer patients.", "content": "Effect of chemotherapeutic agents upon microorganisms isolated from cancer patients. Attempting to explain the predominance of Pseudomonas in leukemic patients, five of the most common gram-negative organisms isolated from sites of infection in cancer patients were exposed to several of the chemotherapeutic agents used in the treatment of this disease (methotrexate, cytosine arabinoside, cyclophosphamide, and 6-mercaptopurine). At concentrations of 125 mug/ml or higher, methotrexate inhibited all organisms except Pseudomonas. Cytosine arabinoside inhibited Escherichia and Klebsiella but appeared to stimulate the growth of Pseudomonas slightly at the higher concentrations. Thus, significant differences existed in individual susceptibilities to these agents. Clinical isolates were more resistant than the corresponding laboratory strains not previously exposed to these compounds. The resistance of Escherichia coli to cyclophosphamide was decreased 26% when it was grown in mixed culture with Pseudomonas. Only Pseudomonas was resistant to all of these compounds whether in pure or mixed culture. These observations may help to explain, in part, the predominant role that Pseudomonas plays as an infectious agent in leukemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208899"} {"pmid": "4208900", "title": "Scanning electron microscopy of the H37Ra strain of Mycobacterium tuberculosis exposed to isoniazid.", "content": "Scanning electron microscopy of the H37Ra strain of Mycobacterium tuberculosis exposed to isoniazid. The morphology of cells of the H37Ra strain of Mycobacterium tuberculosis exposed to 0.5 mug of isonicotinic acid hydrazide (isoniazid) per ml was examined by scanning electron microscopy (SEM). Cells that were exposed to isoniazid for 3 h showed no detectable change, whereas cells exposed to the drug for 24 h exhibited diverse morphological features. From our examination of these SEM pictures, we have reconstructed the probable sequence of morphological changes to be as follows: (i) the wrinkling of the cell surface was ascribed as the earliest observable change, (ii) the cell surface then became very rough and ragged, (iii) eventually the cytoplasmic material was extruded from the cell, (iv) this event produced a collapsed cell, (v) the cells began to fragment, (vi) the fragmented cells then coalesced to form an amorphous mass of cell debris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208900"} {"pmid": "4208901", "title": "Bactericidal action of an antibiotic produced by Myxococcus xanthus.", "content": "Bactericidal action of an antibiotic produced by Myxococcus xanthus. Myxococcus xanthus produced an antibiotic during the end of its exponential growth phase which was capable of inhibiting growth of several gram-positive and gram-negative bacteria. The antibiotic was bactericidal to growing cultures only; chloramphenicol inhibited the bactericidal action of the antibiotic. Upon addition of the antibiotic to Escherichia coli B, deoxyribonucleic acid and ribonucleic acid as well as turbidity of the culture continued to increase even after the viable count decreased; the culture lysed about 60 min after addition of sufficient concentrations of the antibiotic. Spheroplasts could be prepared if the antibiotic was added to a culture growing in the presence of high concentrations of sucrose and MgSO(4). Mutants of M. xanthus FB which are incapable of fruiting body formation or glycerol-induced myxospore formation also produced the antibiotic. A mutant of E. coli resistant to the purified antibiotic was isolated in order to study the role of the antibiotic in the predatory behavior of myxococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208901"} {"pmid": "4208902", "title": "Streptococcal pharyngitis therapy: comparison of clindamycin palmitate and potassium phenoxymethyl penicillin.", "content": "Streptococcal pharyngitis therapy: comparison of clindamycin palmitate and potassium phenoxymethyl penicillin. Clindamycin palmitate and potassium phenoxymethyl penicillin were evaluated in 103 children with upper respiratory illnesses and pharyngeal group A streptococci, from November 1970 to July 1971. The children were assigned randomly by weight to one of the antibiotic regimens given orally for 10 days. Clindamycin palmitate and potassium phenoxymethyl penicillin dosages were 75 and 125 mg, respectively, in 5 ml tid for children weighing less than 25 kg, and 150 and 250 mg, respectively, in 10 ml bid for children weighing 25 kg or more. Recurrences of the original streptococcal group A, M, and T types within 3 weeks after the end of treatment were classified as failures. The failure rates were: clindamycin palmitate, 10% (5 of 52), and potassium phenoxymethyl penicillin, 18% (9 of 51). Possible drug-related rashes were observed in 8 of 52 clindamycin palmitate-treated patients. The geometric mean minimal inhibitory concentrations of clindamycin and penicillin against 103 isolates of group A streptococci were 0.033 and 0.007 mug/ml, respectively. The serum concentrations about 70 min after ingesting 150 mg of clindamycin palmitate averaged 3.8 mug/ml and after 250 mg of potassium phenoxymethyl penicillin averaged 0.9 mug/ml. Clindamycin palmitate was as effective as potassium phenoxymethyl penicillin in eradicating group A streptococci from the pharynx in tid and bid regimens. Nevertheless, because of its rash-producing tendency in some patients and higher cost, clindamycin palmitate should not be preferred to penicillin for treatment of streptococcal sore throat in the non-penicillin-allergic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208902"} {"pmid": "4208904", "title": "Letter: Chronic brucellosis.", "content": "Letter: Chronic brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208904"} {"pmid": "4208905", "title": "Letter: Treatment of meningococcal carriers.", "content": "Letter: Treatment of meningococcal carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208905"} {"pmid": "4208906", "title": "Variation in the occurrence of extracellular diffusible antigens in temperature-induced variants of Erwinia herbicola Y46, and observations of their relationships with Erwinia amylovora.", "content": "Variation in the occurrence of extracellular diffusible antigens in temperature-induced variants of Erwinia herbicola Y46, and observations of their relationships with Erwinia amylovora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208906"} {"pmid": "4208907", "title": "The in vitro degradation of the herbicide bromoxynil.", "content": "The in vitro degradation of the herbicide bromoxynil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208907"} {"pmid": "4208908", "title": "Endotracheally administered gentamicin for the prevention of infections of the respiratory tract in patients with tracheostomy: a double-blind study.", "content": "Endotracheally administered gentamicin for the prevention of infections of the respiratory tract in patients with tracheostomy: a double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208908"} {"pmid": "4208909", "title": "Australia hepatitis-associated antigen in cirrhosis of the liver at Aurangabad.", "content": "Australia hepatitis-associated antigen in cirrhosis of the liver at Aurangabad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208909"} {"pmid": "4208910", "title": "Haemagglutination by Chikungunya virus--pH range and erythrocytes of different animals.", "content": "Haemagglutination by Chikungunya virus--pH range and erythrocytes of different animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208910"} {"pmid": "4208911", "title": "Nematodes in rhesus monkeys.", "content": "Nematodes in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208911"} {"pmid": "4208912", "title": "Kinetics of formation and dissociation of manganese-bovine carbonic anhydrase B.", "content": "Kinetics of formation and dissociation of manganese-bovine carbonic anhydrase B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208912"} {"pmid": "4208914", "title": "The relationship between PF-DIL and activated human Hageman factor.", "content": "The relationship between PF-DIL and activated human Hageman factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208914"} {"pmid": "4208913", "title": "Hypothalamic regulatory hormones: a review.", "content": "Hypothalamic regulatory hormones: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208913"} {"pmid": "4208915", "title": "IgM-forming cells as the immediate precursor of IgA-producing cells during ontogeny of the immunoglobulin-producing system of the chicken.", "content": "IgM-forming cells as the immediate precursor of IgA-producing cells during ontogeny of the immunoglobulin-producing system of the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208915"} {"pmid": "4208916", "title": "Dissociation and recombination of the subunits of the cholera enterotoxin (choleragen).", "content": "Dissociation and recombination of the subunits of the cholera enterotoxin (choleragen).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208916"} {"pmid": "4208917", "title": "Chain interactions and idiotypic specificities of homogeneous rabbit anti-lactose antibodies.", "content": "Chain interactions and idiotypic specificities of homogeneous rabbit anti-lactose antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208917"} {"pmid": "4208918", "title": "Effector mechanisms of cell-mediated immunity to xenogeneic cell antigens.", "content": "Effector mechanisms of cell-mediated immunity to xenogeneic cell antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208918"} {"pmid": "4208919", "title": "Interaction of isoantibody and cytotoxic lymphocytes with allogeneic tumor cells.", "content": "Interaction of isoantibody and cytotoxic lymphocytes with allogeneic tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208919"} {"pmid": "4208920", "title": "Modification of NZB-NZW F1 autoimmune disease by development of tolerance to DNA.", "content": "Modification of NZB-NZW F1 autoimmune disease by development of tolerance to DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208920"} {"pmid": "4208921", "title": "Crossed immunoelectrophoresis and electroimmunoassay of IgG.", "content": "Crossed immunoelectrophoresis and electroimmunoassay of IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208921"} {"pmid": "4208922", "title": "The occurrence of shared idiotypic specificity among the goat antibodies that distinguish human hemoglobin S from A.", "content": "The occurrence of shared idiotypic specificity among the goat antibodies that distinguish human hemoglobin S from A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208922"} {"pmid": "4208923", "title": "Serum immunoglobulin E levels in patients with neoplastic disease.", "content": "Serum immunoglobulin E levels in patients with neoplastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208923"} {"pmid": "4208924", "title": "Studies on human secretory immunoglobulin A. VI. Cyanogen bromide cleavage.", "content": "Studies on human secretory immunoglobulin A. VI. Cyanogen bromide cleavage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208924"} {"pmid": "4208925", "title": "Prevention of myeloma growth in BALB-c mice by injection of anti-immunoglobulin antisera.", "content": "Prevention of myeloma growth in BALB-c mice by injection of anti-immunoglobulin antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208925"} {"pmid": "4208926", "title": "Interaction of C-reactive protein complexes with the complement system. II. Consumption of guinea pig complement by CRP complexes: requirement for human C1q.", "content": "Interaction of C-reactive protein complexes with the complement system. II. Consumption of guinea pig complement by CRP complexes: requirement for human C1q.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208926"} {"pmid": "4208927", "title": "The diagnosis of ruptured fetal membranes by measurement of the diamine oxidase (DAO) activity in vaginal fluid.", "content": "The diagnosis of ruptured fetal membranes by measurement of the diamine oxidase (DAO) activity in vaginal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208927"} {"pmid": "4208939", "title": "Letter: Alcoholic cirrhosis in baboons.", "content": "Letter: Alcoholic cirrhosis in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208939"} {"pmid": "4208938", "title": "Comparative studies of alpha-lactalbumin and lysozyme: Echidna lysozyme.", "content": "Comparative studies of alpha-lactalbumin and lysozyme: Echidna lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208938"} {"pmid": "4208962", "title": "Effects of dihydrotestosterone on sexual behavior of castrated male rhesus monkeys.", "content": "Effects of dihydrotestosterone on sexual behavior of castrated male rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208962"} {"pmid": "4208960", "title": "A study of the histologic reaction of submerged root segments.", "content": "A study of the histologic reaction of submerged root segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208960"} {"pmid": "4208963", "title": "Schedule-induced drinking following omission of reinforcement in the rhesus monkey.", "content": "Schedule-induced drinking following omission of reinforcement in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208963"} {"pmid": "4208961", "title": "Normal physiological patterns and physiological-behavioral correlations in unrestrained monkey infants.", "content": "Normal physiological patterns and physiological-behavioral correlations in unrestrained monkey infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208961"} {"pmid": "4208965", "title": "Correlation of physical characteristics of 4 MV X-ray beams with skin reactions of patients undergoing radiation therapy.", "content": "Correlation of physical characteristics of 4 MV X-ray beams with skin reactions of patients undergoing radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208965"} {"pmid": "4208964", "title": "Irradiation in the local control of malignant lymphoreticular tumors (non-Hodgkin's malignant lymphoma).", "content": "Irradiation in the local control of malignant lymphoreticular tumors (non-Hodgkin's malignant lymphoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208964"} {"pmid": "4208970", "title": "Functional and histological findings in acoustic tumor.", "content": "Functional and histological findings in acoustic tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208970"} {"pmid": "4208968", "title": "Mechanisms of renal excretion of urate in the rat.", "content": "Mechanisms of renal excretion of urate in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208968"} {"pmid": "4208969", "title": "Tuberculous cervical lymphadenitis.", "content": "Tuberculous cervical lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208969"} {"pmid": "4208972", "title": "Methionine transfer RNAs from the blue-green alga Anacystis nidulans.", "content": "Methionine transfer RNAs from the blue-green alga Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208972"} {"pmid": "4208974", "title": "Proceedings: The intracranial volume-pressure response during experimental brain compression in primates.", "content": "Proceedings: The intracranial volume-pressure response during experimental brain compression in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208974"} {"pmid": "4208971", "title": "Cardiolipin specific phospholipase D activity in Escherichia coli extracts.", "content": "Cardiolipin specific phospholipase D activity in Escherichia coli extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208971"} {"pmid": "4208973", "title": "Peroperative evaluation of the viability of ischaemic colon in primates.", "content": "Peroperative evaluation of the viability of ischaemic colon in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208973"} {"pmid": "4208975", "title": "Proceedings: Comparison of central venous pressure with continuous blood volume measurement during haemorrhage and infusion.", "content": "Proceedings: Comparison of central venous pressure with continuous blood volume measurement during haemorrhage and infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208975"} {"pmid": "4208978", "title": "Editorial: Budget cuts are not the answer.", "content": "Editorial: Budget cuts are not the answer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208978"} {"pmid": "4208959", "title": "Neutralizing and precipitating antibodies against infectious bronchitis virus in chickens.", "content": "Neutralizing and precipitating antibodies against infectious bronchitis virus in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208959"} {"pmid": "4208979", "title": "Classification of hypothyroidism in evaluating patients after radioiodine therapy by serum cholesterol, T3-uptake. Total T4, FT4-index, total T3, basal TSH and TRH-test.", "content": "Classification of hypothyroidism in evaluating patients after radioiodine therapy by serum cholesterol, T3-uptake. Total T4, FT4-index, total T3, basal TSH and TRH-test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208979"} {"pmid": "4208981", "title": "Basement membrane abnormalities in melanotic tumor formation of Drosophila.", "content": "Basement membrane abnormalities in melanotic tumor formation of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208981"} {"pmid": "4208980", "title": "Intramitochondrial bodies in the B-cells of rat's pancreas treated by glybenclamide.", "content": "Intramitochondrial bodies in the B-cells of rat's pancreas treated by glybenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208980"} {"pmid": "4208982", "title": "Antibodies to the insect moulting hormone beta-ecdysone.", "content": "Antibodies to the insect moulting hormone beta-ecdysone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208982"} {"pmid": "4208989", "title": "Review of progress and application in acoustis microscopy.", "content": "Review of progress and application in acoustis microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208989"} {"pmid": "4208987", "title": "Australia antigen in the Solomon Islands.", "content": "Australia antigen in the Solomon Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208987"} {"pmid": "4208988", "title": "Fine structure and function of ocular tissues. The optic nerve.", "content": "Fine structure and function of ocular tissues. The optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208988"} {"pmid": "4208991", "title": "The dorsal thalamus of the cat and comparison with monkey and man.", "content": "The dorsal thalamus of the cat and comparison with monkey and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208991"} {"pmid": "4208994", "title": "Products of linoleic hydroperoxide-decomposing enzyme of alfalfa seed.", "content": "Products of linoleic hydroperoxide-decomposing enzyme of alfalfa seed. Alfalfa seeds and seedlings contain an enzyme that catalyzes a reaction with the 13- and 9-hydroperoxides of linoleic acid to form 13-hydroxy-10-oxo-trans-octadecenoic acid and 9-hydroxy-12-oxo-trans-10-octadecenoic acid, respectively. When commercial lipoxygenase is used to generate the hydroperoxides, the above acids appear in about 2:1 proportions, respectively. The products of the action of the enzyme on the hydroperoxides were stabilized for analysis by reduction with H(2) and LiAIH(4). Trimethylsilyl derivatives of reduced products were analyzed by combined gas-liquid chromatography-mass spectrometry. Specific deuterium labeling permitted definite location of the oxo functions. (18)O(2) labeling experiments showed that the oxygens of both the oxo and the hydroxyl functions were derived from the hydroperoxide. Retention of both oxygens suggests that the reaction proceeds through a cyclic epiperoxide followed by a ketohydroxy-forming rearrangement. No products of hydroperoxide isomerase were found in reactions catalyzed by the crude enzyme from alfalfa seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208994"} {"pmid": "4208993", "title": "Cholesterol metabolism in rhesus monkey, squirrel monkey, and baboon.", "content": "Cholesterol metabolism in rhesus monkey, squirrel monkey, and baboon. The metabolism of cholesterol was studied in baboons, rhesus monkeys, and squirrel monkeys while they were being fed either a low fat, low cholesterol (basal) diet or the basal diet supplemented with saturated fat and cholesterol (atherogenic diet). When the diet was changed from basal to atherogenic, the mean total serum cholesterol concentration increased from 70 to 180 mg/dl in the baboon, from 168 to 283 mg/dl in the squirrel monkey, and from 144 to 608 mg/dl in the rhesus monkey. In animals fed the atherogenic diet, the percentage of dietary cholesterol absorbed was greatest in the rhesus monkey and least in the baboon. The fraction of the total body pool of cholesterol that was derived from the diet was greatest in the squirrel monkey and least in the baboon. The turnover of the body pool of cholesterol was several times faster in the squirrel monkey than in the baboon or the rhesus monkey when either dict was fed. The mean total fecal excretion of endogenous cholesterol and bile acid increased in all species on transition to the atherogenic diet; however, the relative contributions of the neutral and acidic fractions to the increase in total excretion differed among species. The difference in percentage of dietary cholesterol absorbed may, in part, account for the large differences in serum cholesterol during the atherogenic diet period. Comparison with other published results indicates that of these species cholesterol metabolism in the baboon is most like that in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208993"} {"pmid": "4208995", "title": "Artifacts produced by acidic hydrolysis of lipids containing 3-hydroxyalkanoic acids.", "content": "Artifacts produced by acidic hydrolysis of lipids containing 3-hydroxyalkanoic acids. After acidic hydrolysis of lipid A preparations from pseudomonads, products containing both hydroxy and nonhydroxy fatty acids were obtained. The major products were alkanoate esters of the hydroxy acids. Similar compounds were formed when a 3-hydroxy acid was heated with a nonhydroxy acid under the same conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208995"} {"pmid": "4208996", "title": "Anti-C, anti-e and anti-Ce (rhi) as a cause of hemolytic disease of the newborn in a Thai family.", "content": "Anti-C, anti-e and anti-Ce (rhi) as a cause of hemolytic disease of the newborn in a Thai family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208996"} {"pmid": "4208997", "title": "The need for trained medical professionals.", "content": "The need for trained medical professionals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208997"} {"pmid": "4208998", "title": "Drug rehabilitation in the combat zone.", "content": "Drug rehabilitation in the combat zone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208998"} {"pmid": "4208999", "title": "Categorization of seizure disorders in combat zone evacuees.", "content": "Categorization of seizure disorders in combat zone evacuees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208999"} {"pmid": "4209000", "title": "Case for diagnosis.", "content": "Case for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209000"} {"pmid": "4209001", "title": "Home dialysis experience at Madigan Army Medical Center.", "content": "Home dialysis experience at Madigan Army Medical Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209001"} {"pmid": "4209002", "title": "Methoxyflurane nephrotoxicity: case report.", "content": "Methoxyflurane nephrotoxicity: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209002"} {"pmid": "4208990", "title": "Pulpal response of monkeys to a composite resin cement.", "content": "Pulpal response of monkeys to a composite resin cement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4208990"} {"pmid": "4209003", "title": "Donnatal intoxication: case report.", "content": "Donnatal intoxication: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209003"} {"pmid": "4209004", "title": "Delayed infection following tantalum cranioplasty: case report.", "content": "Delayed infection following tantalum cranioplasty: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209004"} {"pmid": "4209005", "title": "Subarachnoid hemorrhage presenting as cardiac arrhythmia: case report.", "content": "Subarachnoid hemorrhage presenting as cardiac arrhythmia: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209005"} {"pmid": "4209006", "title": "Editorial: oral fluid intake accuracy.", "content": "Editorial: oral fluid intake accuracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209006"} {"pmid": "4209007", "title": "Progressive ossification of the leptomeninges in atrophic encephalopathy.", "content": "Progressive ossification of the leptomeninges in atrophic encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209007"} {"pmid": "4209021", "title": "Ion exchange and affinity chromatography during the purification of human plasminogen on sepharose-L-lysine.", "content": "Ion exchange and affinity chromatography during the purification of human plasminogen on sepharose-L-lysine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209021"} {"pmid": "4209023", "title": "Did this boy have meningitis?", "content": "Did this boy have meningitis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209023"} {"pmid": "4209022", "title": "Eight children with coexistent sickle cell anemia and plumbism.", "content": "Eight children with coexistent sickle cell anemia and plumbism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209022"} {"pmid": "4209024", "title": "Candida endocarditis and encephalitis in an infant.", "content": "Candida endocarditis and encephalitis in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209024"} {"pmid": "4209025", "title": "Candida endocarditis complicating glucose total intravenous nutrition.", "content": "Candida endocarditis complicating glucose total intravenous nutrition. A case of Candida albicans endocarditis is reported. The endocarditis occurred in a patient with a chronic illness who received intermittent glucose total intravenous nutrition for approximately 10 weeks. The patient developed severe aortic insufficiency with his valvular endocarditis and required emergency aortic valve replacement. Aggressive surgery and medical treatment appear to be the treatment of choice for these critically ill patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209025"} {"pmid": "4209027", "title": "Novel human serum protein from fibroblast plasma membrane.", "content": "Novel human serum protein from fibroblast plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209027"} {"pmid": "4209028", "title": "Review: The endocrine glands in infantile malnutrition.", "content": "Review: The endocrine glands in infantile malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209028"} {"pmid": "4209029", "title": "Oxidation of phenols by cells and cell-free enzymes from Candida tropicalis.", "content": "Oxidation of phenols by cells and cell-free enzymes from Candida tropicalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209029"} {"pmid": "4209030", "title": "Proceedings: Immunoglobulins in early syphilis.", "content": "Proceedings: Immunoglobulins in early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209030"} {"pmid": "4209031", "title": "The influence of repeated and prolonged stimulation on the PHA-response of lymphocytes in Hodgkin's disease.", "content": "The influence of repeated and prolonged stimulation on the PHA-response of lymphocytes in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209031"} {"pmid": "4209032", "title": "Enhanced uptake of anti-Rho coated red cells by cultured human monocytes.", "content": "Enhanced uptake of anti-Rho coated red cells by cultured human monocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209032"} {"pmid": "4209034", "title": "Lysozyme-negative, peroxidase-positive mononuclear cells: a new kinetically distinct cell population in normal rat blood.", "content": "Lysozyme-negative, peroxidase-positive mononuclear cells: a new kinetically distinct cell population in normal rat blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209034"} {"pmid": "4209035", "title": "Splenic feedback in red cell regeneration.", "content": "Splenic feedback in red cell regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209035"} {"pmid": "4209036", "title": "'Nonsecretory' multiple myeloma. Report of a case.", "content": "'Nonsecretory' multiple myeloma. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209036"} {"pmid": "4209038", "title": "Effect of glucose on the biosynthesis of the membranes of Bacillus.", "content": "Effect of glucose on the biosynthesis of the membranes of Bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209038"} {"pmid": "4209040", "title": "Grey scale echography in the diagnosis of intrahepatic disease.", "content": "Grey scale echography in the diagnosis of intrahepatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209040"} {"pmid": "4209041", "title": "Ultrasound studies in premature infants after birth.", "content": "Ultrasound studies in premature infants after birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209041"} {"pmid": "4209042", "title": "Letter: Fetal biparietal diameters correlated with gestational age.", "content": "Letter: Fetal biparietal diameters correlated with gestational age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209042"} {"pmid": "4209039", "title": "Effects of ions on vesicles and phospholipid dispersions studied by polarization of fluorescence.", "content": "Effects of ions on vesicles and phospholipid dispersions studied by polarization of fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209039"} {"pmid": "4209043", "title": "Proceedings: Studies on glucuronic acid metabolism: effect of uridine diphosphate glucuronic acid and thiol groups on the enzymes in the glucuronic acid metabolism series.", "content": "Proceedings: Studies on glucuronic acid metabolism: effect of uridine diphosphate glucuronic acid and thiol groups on the enzymes in the glucuronic acid metabolism series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209043"} {"pmid": "4209044", "title": "Proceedings: Possible mechanism of action of methyldopa: relationship studies between route on administration, dose, plasma concentration and hemodynamic changes in conscious monkeys.", "content": "Proceedings: Possible mechanism of action of methyldopa: relationship studies between route on administration, dose, plasma concentration and hemodynamic changes in conscious monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209044"} {"pmid": "4209045", "title": "Proceedings: Studies on drug dependence report. 19: quantitative evaluation of reinforcing effect on drug-seeking behavior.", "content": "Proceedings: Studies on drug dependence report. 19: quantitative evaluation of reinforcing effect on drug-seeking behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209045"} {"pmid": "4209046", "title": "Epidemiologic aspects of nontuberculous mycobacterial disease and of tuberculosis in British Columbia.", "content": "Epidemiologic aspects of nontuberculous mycobacterial disease and of tuberculosis in British Columbia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209046"} {"pmid": "4209048", "title": "Evidence for two immunologically distinct acetyl-co-enzyme A synthetase in yeast.", "content": "Evidence for two immunologically distinct acetyl-co-enzyme A synthetase in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209048"} {"pmid": "4209049", "title": "Effect of photooxidation of bacterial liquefying alpha-amylase dependent on the degree of polymerization of linear substrates.", "content": "Effect of photooxidation of bacterial liquefying alpha-amylase dependent on the degree of polymerization of linear substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209049"} {"pmid": "4209047", "title": "UV irradiation of poplar cells of Drosophila melanogaster embryos. V. A study of the meiotic recombination in females with chromosomes of different structure.", "content": "UV irradiation of poplar cells of Drosophila melanogaster embryos. V. A study of the meiotic recombination in females with chromosomes of different structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209047"} {"pmid": "4209053", "title": "Degradation of tuberculoproteins by cathepsin D-type proteinase of alveolar and peritoneal macrophages of mice.", "content": "Degradation of tuberculoproteins by cathepsin D-type proteinase of alveolar and peritoneal macrophages of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209053"} {"pmid": "4209050", "title": "Population genetics in the American Tropics. IX. Rhythmic genetic changes that prove the adaptive nature of the detrimental load in Drosophila melanogaster from Caracolisito, Colombia.", "content": "Population genetics in the American Tropics. IX. Rhythmic genetic changes that prove the adaptive nature of the detrimental load in Drosophila melanogaster from Caracolisito, Colombia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209050"} {"pmid": "4209052", "title": "In vitro activity of cephalosporins against Mycobacterium tuberculosis H37Rv: structure-activity relationships.", "content": "In vitro activity of cephalosporins against Mycobacterium tuberculosis H37Rv: structure-activity relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209052"} {"pmid": "4209051", "title": "Metabolism of lysolecithin in vivo and in vitro with particular emphasis on the arterial wall.", "content": "Metabolism of lysolecithin in vivo and in vitro with particular emphasis on the arterial wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209051"} {"pmid": "4209054", "title": "Slime production by Pseudomonas aeruginosa. IV. Chemical analysis of two varieties of slime produced by Pseudomonas aeruginosa.", "content": "Slime production by Pseudomonas aeruginosa. IV. Chemical analysis of two varieties of slime produced by Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209054"} {"pmid": "4209055", "title": "Stability of frozen solutions of cephapirin sodium.", "content": "Stability of frozen solutions of cephapirin sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209055"} {"pmid": "4209056", "title": "Diethylpropion hydrochloride (Tenuate Dospan) in combination with hypotensive agents in the treatment of obesity associated with hypertension.", "content": "Diethylpropion hydrochloride (Tenuate Dospan) in combination with hypotensive agents in the treatment of obesity associated with hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209056"} {"pmid": "4209057", "title": "Tobramycin therapy of pulmonary infections in patients with cystic fibrosis.", "content": "Tobramycin therapy of pulmonary infections in patients with cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209057"} {"pmid": "4209058", "title": "Clinical experience with doxycycline in the treatment of surgical soft-tissue infections.", "content": "Clinical experience with doxycycline in the treatment of surgical soft-tissue infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209058"} {"pmid": "4209059", "title": "Treatment of otitis externa: a controlled bacteriological-clinical evaluation.", "content": "Treatment of otitis externa: a controlled bacteriological-clinical evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209059"} {"pmid": "4209060", "title": "Prevention of swimmer's ear by simple prophylactic regimen.", "content": "Prevention of swimmer's ear by simple prophylactic regimen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209060"} {"pmid": "4209061", "title": "Tolmetin versus placebo for the treatment of rheumatoid arthritis: a sequential double-blind clinical trial.", "content": "Tolmetin versus placebo for the treatment of rheumatoid arthritis: a sequential double-blind clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209061"} {"pmid": "4209062", "title": "Doxepin versus amitriptyline in depression: a sequential double-blind study.", "content": "Doxepin versus amitriptyline in depression: a sequential double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209062"} {"pmid": "4209064", "title": "Effect of CDP-choline in experimental cerebral hemorrhage.", "content": "Effect of CDP-choline in experimental cerebral hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209064"} {"pmid": "4209063", "title": "An early clinical trial of lenperone (AHR 2277), a butyrophenone, in chronic schizophrenia.", "content": "An early clinical trial of lenperone (AHR 2277), a butyrophenone, in chronic schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209063"} {"pmid": "4209067", "title": "Antibiotic disk susceptibility tests with Neisseria gonorrhoeae.", "content": "Antibiotic disk susceptibility tests with Neisseria gonorrhoeae. We have used a standardized disk diffusion procedure to test the susceptibility of 892 isolates of Neisseria gonorrhoeae to six antibiotics. The disk diffusion test described is a modification of the disk test of Bauer, Kirby, Sherris, and Turck, which is widely used for susceptibility testing of fast-growing, aerobic pathogens. With all six antibiotics (penicillin, ampicillin, tetracycline, erythromycin, chloramphenicol, and cephaloridine), disk test results were found to be reproducible and correlated well with the minimal inhibitory concentration as determined by an agar dilution procedure. The coefficients of correlation ranged from -0.79 with cephaloridine to -0.93 with penicillin. The technique described for disk susceptibility testing of gonococci can be used both for research and clinical purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209067"} {"pmid": "4209068", "title": "Semiautomated turbidimetric microbiological assay for determination of cefazolin.", "content": "Semiautomated turbidimetric microbiological assay for determination of cefazolin. The Autoturb System, a semiautomated system for photometric bioassay, was used to determine cefazolin content. Suitable conditions for the assay using Streptococcus faecalis ATCC 10541 as the indicator organism included a medium pH of 6.0 to 7.0 and an incubation time of 3 to 3.5 h at 36 C. Multiple independent assays of samples from a common batch showed the test to be highly reproducible. Accuracy of the turbidimetric assay was evaluated by comparing data obtained from a chemical (hydroxylamine) and a biological (disk diffusion) assay. The available data show the turbidimetric assay to be a rapid, accurate, and reproducible method for determining the biological activity of cefazolin samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209068"} {"pmid": "4209069", "title": "Dissociation between results of in vitro and in vivo antibiotic susceptibility tests for some strains of Pseudomonas aeruginosa.", "content": "Dissociation between results of in vitro and in vivo antibiotic susceptibility tests for some strains of Pseudomonas aeruginosa. The relative efficacy in vivo of the polymyxin and aminoglycoside antibiotics in experimental Pseudomonas infection has apparently never been established. This study was designed to determine such efficacy in experimental infection of mice. Eleven strains of Pseudomonas aeruginosa were selected for the study, representing six of the seven recognized immunotypes. All strains were susceptible to colistin, gentamicin, and tobramycin in vitro, and all were virulent for mice. None was lethal because of preformed toxins. Infections were established in mice by intraperitoneal (i.p.) injection of 100 ID(50) of bacteria (infectious doses that would kill 50% of the mice). Graduated doses of antibiotics or saline were given subcutaneously 1 h later. Infections by three strains of P. aeruginosa were cured by low doses of all three antibiotics. Infections by two strains were relatively resistant in vivo to all three antibiotics. Infections by seven strains were relatively resistant in vivo to colistimethate. For most strains, colistimethate was less effective in vivo than gentamicin or tobramycin. To determine the influence of the size of the bacterial inoculum upon the results of chemotherapy, groups of mice were infected with serial dilutions of bacterial suspensions and treated with antibiotics. The antibiotics were more effective when a lighter bacterial inoculum was used. However, colistimethate at 30 mg/kg failed to cure some infections established with an inoculum of only 10 ID(50). To examine the possibility that death despite apparently adequate chemotherapy might be due to bacterial lysis and delayed release of toxins, numbers of viable bacteria in the peritoneal cavity of treated animals were determined by colony count. Antibiotic failure by colistimethate was associated with a steady rise in the number of i.p. bacteria. The findings support the conclusion that i.p. infections in mice with some strains of P. aeruginosa that are fully susceptible in vitro are relatively resistant to chemotherapy in vivo. The dissociation between in vitro and in vivo results was greatest for colistimethate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209069"} {"pmid": "4209071", "title": "Selective phosphorylation of the 5''-hydroxy group of ribostamycin by a new enzyme from Pseudomonas aeruginosa.", "content": "Selective phosphorylation of the 5''-hydroxy group of ribostamycin by a new enzyme from Pseudomonas aeruginosa. It was found that the 5''-hydroxy group of ribostamycin was preferentially phosphorylated by a cell-free extract from Pseudomonas aeruginosa GN 573, a clinical isolate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209071"} {"pmid": "4209070", "title": "Biological assay of streptonigrin (NSC 45383) in body fluids and tissues of mice.", "content": "Biological assay of streptonigrin (NSC 45383) in body fluids and tissues of mice. Streptonigrin, a quinone antitumor antibiotic, has been reported to be effective in human trials. A sensitive and precise microbiological assay for the determination of distribution and concentrations of streptonigrin in the body fluids and tissues of treated mice has been developed in an attempt to supplement successful clinical application of this drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209070"} {"pmid": "4209075", "title": "Ecology of Simuliidae, Mermithidae, and Microsporida in Newfoundland freshwaters.", "content": "Ecology of Simuliidae, Mermithidae, and Microsporida in Newfoundland freshwaters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209075"} {"pmid": "4209074", "title": "Diabetic ketosis.", "content": "Diabetic ketosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209074"} {"pmid": "4209076", "title": "The effect of extracellualr calcium on thermal excitability of the sensory units in the tooth of the cat.", "content": "The effect of extracellualr calcium on thermal excitability of the sensory units in the tooth of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209076"} {"pmid": "4209079", "title": "Letter: Minimal effective dosage of cromolyn.", "content": "Letter: Minimal effective dosage of cromolyn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209079"} {"pmid": "4209080", "title": "Letter: Families with high serum enzyme levels.", "content": "Letter: Families with high serum enzyme levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209080"} {"pmid": "4209078", "title": "Editorial: Slow virus infections.", "content": "Editorial: Slow virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209078"} {"pmid": "4209081", "title": "Loss of visual suppression of vestibular nystagmus after flocculus lesions.", "content": "Loss of visual suppression of vestibular nystagmus after flocculus lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209081"} {"pmid": "4209077", "title": "Idiopathic membrano-proliferative glomerulonephritis in children (corrections between light, electron, immunofluorescent microscopic appearances and serum C3 and C4 levels).", "content": "Idiopathic membrano-proliferative glomerulonephritis in children (corrections between light, electron, immunofluorescent microscopic appearances and serum C3 and C4 levels).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209077"} {"pmid": "4209086", "title": "Fine structure of Haemoproteus columbae Kruse during differentiation of the ookinete.", "content": "Fine structure of Haemoproteus columbae Kruse during differentiation of the ookinete.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209086"} {"pmid": "4209087", "title": "Fine structure of differentiating oocysts and mature sporozoites of Haemoproteus metchnikovi in its intermediate host Chrysops callidus.", "content": "Fine structure of differentiating oocysts and mature sporozoites of Haemoproteus metchnikovi in its intermediate host Chrysops callidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209087"} {"pmid": "4209085", "title": "A study on procaine and procaine adrenaline injections of the British Pharmacopoeia 1968.", "content": "A study on procaine and procaine adrenaline injections of the British Pharmacopoeia 1968.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209085"} {"pmid": "4209088", "title": "Phosphorus regeneration in fresh-water paramecia.", "content": "Phosphorus regeneration in fresh-water paramecia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209088"} {"pmid": "4209093", "title": "The occurrence of vitellogenin in workers and queens of Apis mellifica and the possibility of its transmission to the queen.", "content": "The occurrence of vitellogenin in workers and queens of Apis mellifica and the possibility of its transmission to the queen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209093"} {"pmid": "4209092", "title": "Beta-alanine and adaptation in Drosophila.", "content": "Beta-alanine and adaptation in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209092"} {"pmid": "4209094", "title": "Precipitation of myelin basic protein by beta-lipoprotein of human serum. A study of similarities and differences of the precipitation in normal sera and sera from patients with multiple sclerosis.", "content": "Precipitation of myelin basic protein by beta-lipoprotein of human serum. A study of similarities and differences of the precipitation in normal sera and sera from patients with multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209094"} {"pmid": "4209095", "title": "Cellular patterns of differing circadian rhythms and levels of RNA synthesis in Drosophila salivary glands.", "content": "Cellular patterns of differing circadian rhythms and levels of RNA synthesis in Drosophila salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209095"} {"pmid": "4209101", "title": "Antigenic reactivity of inactivated Bacillus subtilis enzyme preparations.", "content": "Antigenic reactivity of inactivated Bacillus subtilis enzyme preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209101"} {"pmid": "4209102", "title": "Serum IgG, IgA, IgM, and IgE levels and allergy in Filipino children in the United States.", "content": "Serum IgG, IgA, IgM, and IgE levels and allergy in Filipino children in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209102"} {"pmid": "4209072", "title": "Photochemistry of bioactive compounds: photoproducts and kinetics of polychlorinated biphenyls.", "content": "Photochemistry of bioactive compounds: photoproducts and kinetics of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209072"} {"pmid": "4209103", "title": "The effect of changes of dietary calcium concentration on calcium metabolism in sheep.", "content": "The effect of changes of dietary calcium concentration on calcium metabolism in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209103"} {"pmid": "4209104", "title": "Studies on a smooth phage-resistant variant of Brucella abortus. I. Immunological properties.", "content": "Studies on a smooth phage-resistant variant of Brucella abortus. I. Immunological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209104"} {"pmid": "4209105", "title": "Body retention of injected 67Cu in patients with homozygous or heterozygous Wilson's disease and in normal subjects. Comparison of whole-body counting systems.", "content": "Body retention of injected 67Cu in patients with homozygous or heterozygous Wilson's disease and in normal subjects. Comparison of whole-body counting systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209105"} {"pmid": "4209106", "title": "Localization of thyrotropin-releasing factor (TRF) in the hypothalamus of the rat.", "content": "Localization of thyrotropin-releasing factor (TRF) in the hypothalamus of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209106"} {"pmid": "4209073", "title": "Physicochemical appraisal of changes in egg white during storage.", "content": "Physicochemical appraisal of changes in egg white during storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209073"} {"pmid": "4209108", "title": "Cell survival and architectonic differentiation of the hypothalamic mamillary region of the newborn mouse in culture.", "content": "Cell survival and architectonic differentiation of the hypothalamic mamillary region of the newborn mouse in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209108"} {"pmid": "4209107", "title": "Kinetics of thyroxine and triiodothyronine in a case of thyroxine-binding globulin deficiency with hypothyroidism.", "content": "Kinetics of thyroxine and triiodothyronine in a case of thyroxine-binding globulin deficiency with hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209107"} {"pmid": "4209110", "title": "Isolation and characterization of soluble and particulate thyroid iodoproteins in human congenital goiter.", "content": "Isolation and characterization of soluble and particulate thyroid iodoproteins in human congenital goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209110"} {"pmid": "4209109", "title": "Fractionated action of ethylenimine on the rate of mutation in Drosophila melanogaster.", "content": "Fractionated action of ethylenimine on the rate of mutation in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209109"} {"pmid": "4209113", "title": "Proceedings: Pharmacological studies on polychlorobiphenyl (PCB). 3. Effect on the content and metabolism of vitamin B2 and B6, and ascorbic acid in various organs of the rat.", "content": "Proceedings: Pharmacological studies on polychlorobiphenyl (PCB). 3. Effect on the content and metabolism of vitamin B2 and B6, and ascorbic acid in various organs of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209113"} {"pmid": "4209112", "title": "Major urinary protein and immunoglobulin allotypes of recombinant inbred mouse strains.", "content": "Major urinary protein and immunoglobulin allotypes of recombinant inbred mouse strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209112"} {"pmid": "4209116", "title": "Health problems and medical care in Papua New Guinea.", "content": "Health problems and medical care in Papua New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209116"} {"pmid": "4209117", "title": "Sex-linked auxotrophic and putative auxotrophic mutants of Drosophila melanogaster.", "content": "Sex-linked auxotrophic and putative auxotrophic mutants of Drosophila melanogaster. Thirty-two mutants with improved growth response on a yeast-sucrose compared with a defined medium have been characterized with respect to ribonucleoside supplementability. Twenty mutants respond to either pyrimidine ribonucleoside. Four mutants respond to one or both purine ribonucleosides. Eight mutants (\"putative\" auxotrophs) do not respond to dietary RNA supplementation. Mapping and complementation studies suggest that eleven loci are represented: one, rudimentary, probably accounts for all pyrimidine requirers; there are three purine loci and seven at which the putative auxotrophs are found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209117"} {"pmid": "4209111", "title": "Proceedings: Long-term toxicity study of methylmercuric chloride in monkeys.", "content": "Proceedings: Long-term toxicity study of methylmercuric chloride in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209111"} {"pmid": "4209115", "title": "The impact of chemotherapy on the care of patients with tuberculosis.", "content": "The impact of chemotherapy on the care of patients with tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209115"} {"pmid": "4209118", "title": "Development in genetic mosaics of aristapedia, a homoeotic mutant of Drosophila melanogaster.", "content": "Development in genetic mosaics of aristapedia, a homoeotic mutant of Drosophila melanogaster. Development of the homoeotic mutation, aristapedia (ss(a)), was investigated by means of genetic mosaics. The wild-type alleles of aristapedia and the bristle markers yellow, singed, and forked were removed from cells at different times in development by X-ray induced somatic crossing-over. The phenotype of the resulting clones was examined in order to ascertain whether it was leg or antenna. The y sn f; ss(a) clones showed a leg phenotype if induced before the mid-third instar, but showed an antennal phenotype if induced after this time. Late non-expression of ss(a) may be due either to an influence of surrounding ss(+) tissues on the small ss(a) clones, or to a persistence of the effect of ss(+) for one or two cell generations after it is removed from a cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209118"} {"pmid": "4209121", "title": "Congenital lactose intolerance of gastrogen origin associated with cataracts.", "content": "Congenital lactose intolerance of gastrogen origin associated with cataracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209121"} {"pmid": "4209120", "title": "Chemistry of wheat proteins and the nature of the damaging substances.", "content": "Chemistry of wheat proteins and the nature of the damaging substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209120"} {"pmid": "4209123", "title": "Aflatoxins in foods and feedstuffs. 3. Fluorodenisitometric method for determination of aflatoxins M1 and M2 in presence of aflatoxins B1, B2, G1, and G21.", "content": "Aflatoxins in foods and feedstuffs. 3. Fluorodenisitometric method for determination of aflatoxins M1 and M2 in presence of aflatoxins B1, B2, G1, and G21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209123"} {"pmid": "4209122", "title": "Anthyridine and 1,10,11,12-tetraazanaphthacene derivatives: synthesis and biological properties.", "content": "Anthyridine and 1,10,11,12-tetraazanaphthacene derivatives: synthesis and biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209122"} {"pmid": "4209129", "title": "Traumatic lesions of the ankle joint. The supination-external rotation mechanism.", "content": "Traumatic lesions of the ankle joint. The supination-external rotation mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209129"} {"pmid": "4209127", "title": "Camazepam versus diazepam: a double-blind study during endoscopy inspection.", "content": "Camazepam versus diazepam: a double-blind study during endoscopy inspection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209127"} {"pmid": "4209128", "title": "Visual suppression of vestibular nystagmus in rhesus monkeys.", "content": "Visual suppression of vestibular nystagmus in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209128"} {"pmid": "4209126", "title": "Study of a new antihypertensive (guanabenz).", "content": "Study of a new antihypertensive (guanabenz).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209126"} {"pmid": "4209130", "title": "Familial IgA defects.", "content": "Familial IgA defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209130"} {"pmid": "4209136", "title": "Microbial models of mammalian metabolism. Aromatic hydroxylation.", "content": "Microbial models of mammalian metabolism. Aromatic hydroxylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209136"} {"pmid": "4209139", "title": "Lymphocyte-macrophage interaction in resistance to Listeria momocytogenes.", "content": "Lymphocyte-macrophage interaction in resistance to Listeria momocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209139"} {"pmid": "4209140", "title": "Scrub typhus antibody in mammals in three habitats in Sabah.", "content": "Scrub typhus antibody in mammals in three habitats in Sabah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209140"} {"pmid": "4209137", "title": "Changes in conformation and nucleotide binding of Ca, Mn, or MgG-actin upon removal of the bound divalent cation. Studies of ultraviolet difference spectra and optical rotation.", "content": "Changes in conformation and nucleotide binding of Ca, Mn, or MgG-actin upon removal of the bound divalent cation. Studies of ultraviolet difference spectra and optical rotation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209137"} {"pmid": "4209138", "title": "Accumulation of 3H-1-lysine by brain and plasma in male and female rats treated acutely wigh morphine sulfate.", "content": "Accumulation of 3H-1-lysine by brain and plasma in male and female rats treated acutely wigh morphine sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209138"} {"pmid": "4209141", "title": "Protein calorie malnutrition: a major health problem of multiple causation in Malaysia.", "content": "Protein calorie malnutrition: a major health problem of multiple causation in Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209141"} {"pmid": "4209142", "title": "The molecular biology of Euglena gracilis. IX. Amino acid pool composition.", "content": "The molecular biology of Euglena gracilis. IX. Amino acid pool composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209142"} {"pmid": "4209143", "title": "The estimation of serum cholinesterase in the presence of anti-cholinesterase insecticides.", "content": "The estimation of serum cholinesterase in the presence of anti-cholinesterase insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209143"} {"pmid": "4209144", "title": "Antibodies against different viral antigens in cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases.", "content": "Antibodies against different viral antigens in cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209144"} {"pmid": "4209145", "title": "Physiologic and pathophysiologic relationship between the electroencephalogram and the regional cerebral blood flow.", "content": "Physiologic and pathophysiologic relationship between the electroencephalogram and the regional cerebral blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209145"} {"pmid": "4209148", "title": "Multiple myeloma. I. Clinical, biochemical and immunochemical aspects.", "content": "Multiple myeloma. I. Clinical, biochemical and immunochemical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209148"} {"pmid": "4209149", "title": "The ultrastructure of melanoma cells treated with 5-bromodeoxyuridine.", "content": "The ultrastructure of melanoma cells treated with 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209149"} {"pmid": "4209151", "title": "Cannabis: a psychopharmacological review.", "content": "Cannabis: a psychopharmacological review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209151"} {"pmid": "4209154", "title": "Browning of the lens in generalized albinism.", "content": "Browning of the lens in generalized albinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209154"} {"pmid": "4209155", "title": "Circulating autoantibodies in ocular pemphigoid.", "content": "Circulating autoantibodies in ocular pemphigoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209155"} {"pmid": "4209156", "title": "The production of antibodies against mammalian LDH-1.", "content": "The production of antibodies against mammalian LDH-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209156"} {"pmid": "4209157", "title": "Hydroxyapatite column chromatography in procedures for isolation of purified DNA.", "content": "Hydroxyapatite column chromatography in procedures for isolation of purified DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209157"} {"pmid": "4209158", "title": "Testicular lesions in rats treated for one year with ethambutol in low doses.", "content": "Testicular lesions in rats treated for one year with ethambutol in low doses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209158"} {"pmid": "4209160", "title": "Raised intracranial pressure and cerebral blood flow. 3. Venous outflow tract pressures and vascular resistances in experimental intracranial hypertension.", "content": "Raised intracranial pressure and cerebral blood flow. 3. Venous outflow tract pressures and vascular resistances in experimental intracranial hypertension. Pressure changes within the venous outflow tract from the brain were studied in anaesthetized baboons. Segmental vascular resistance changes were also calculated and the results correlated with the changes in cerebral blood flow, measured by the (133)Xenon clearance method. Three different methods were used to raise intracranial pressure: cisterna magna infusion, a supratentorial subdural balloon, and an infratentorial subdural balloon. A close correlation was found between the cortical vein pressure and intracranial pressure with all methods of raising intracranial pressure: the overall correlation coefficient was 0·98. In the majority of animals sagittal sinus pressure showed little change through a wide range of intracranial pressure. In three of the six animals in the cisterna magna infusion group, however, sagittal sinus pressure increased to levels approaching the intracranial pressure during the later stages of intracranial hypertension. Jugular venous pressure showed little change with increasing intracranial pressure. The relationship between cerebral prefusion pressure and cerebral blood flow differed according to the method of increasing intracranial pressure. This was due to differing patterns of change in prevenous vascular resistance as venous resistance increased progressively with increasing pressure in all three groups. The present results confirm, therefore, the validity of the current definition of cerebral perfusion pressure-that is, cerebral perfusion pressure is equal to mean arterial pressure minus mean intracranial pressure-by demonstrating that intracranial pressure does represent the effective cerebral venous outflow pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209160"} {"pmid": "4209159", "title": "Hepatic blood flow and portal vein pressure during intravenous infusion of amino acids in dogs.", "content": "Hepatic blood flow and portal vein pressure during intravenous infusion of amino acids in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209159"} {"pmid": "4209161", "title": "Stereotactic amygdaloidotomy for aggressive behaviour.", "content": "Stereotactic amygdaloidotomy for aggressive behaviour. Amygdaloidotomy was performed bilaterally on 15 and unilaterally on three patients exhibiting severe aggressive or self-mutilating behaviour. Nine subjects (50%) were improved a year after operation; improvement was maintained in seven (39%) for periods ranging from 27 months to nearly six years. Four non-epileptic cases had convulsions during the period of review; one of them has a persistent mild hemiparesis dating from the postoperative period. There was a tendency for epileptics to respond better than non-epileptics and for mentally retarded patients to respond poorly, but none of the differences was statistically significant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209161"} {"pmid": "4209165", "title": "Isocitrate lyase from the free-living nematode, Tubatrix aceti: purification and properties.", "content": "Isocitrate lyase from the free-living nematode, Tubatrix aceti: purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209165"} {"pmid": "4209164", "title": "Intestinal alkaline phosphatase. Physical properties and quaternary structure.", "content": "Intestinal alkaline phosphatase. Physical properties and quaternary structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209164"} {"pmid": "4209166", "title": "Effects of abnormal base ionizations on Mg2 plus binding to transfer ribonucleic acid as studied by a fluorescent probe.", "content": "Effects of abnormal base ionizations on Mg2 plus binding to transfer ribonucleic acid as studied by a fluorescent probe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209166"} {"pmid": "4209167", "title": "Energetics and spectral changes in ligand binding by homogeneous rabbit anti-lactose antibody.", "content": "Energetics and spectral changes in ligand binding by homogeneous rabbit anti-lactose antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209167"} {"pmid": "4209170", "title": "Proceedings: Evaluation of a rat thyrotrophin radioimmunoassay and its applications.", "content": "Proceedings: Evaluation of a rat thyrotrophin radioimmunoassay and its applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209170"} {"pmid": "4209177", "title": "Immune response to Mycobacterium leprae in indeterminate leprosy patients.", "content": "Immune response to Mycobacterium leprae in indeterminate leprosy patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209177"} {"pmid": "4209173", "title": "Hydrolysis of casein by three extracellular proteolytic enzymes from Staphylococcus aureus, strain V8.", "content": "Hydrolysis of casein by three extracellular proteolytic enzymes from Staphylococcus aureus, strain V8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209173"} {"pmid": "4209176", "title": "Agglutinins against group 3 atypical mycobacteria.", "content": "Agglutinins against group 3 atypical mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209176"} {"pmid": "4209172", "title": "Current understanding of human prolactin physiology and its diagnostic and therapeutic applications: a review.", "content": "Current understanding of human prolactin physiology and its diagnostic and therapeutic applications: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209172"} {"pmid": "4209175", "title": "The formation of a calcium-dependent extracellular proteolytic enzyme from Staphylococcus aureus.", "content": "The formation of a calcium-dependent extracellular proteolytic enzyme from Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209175"} {"pmid": "4209178", "title": "Rabbit anti rat lymphocyte serum: immunosuppression mediated by a pure IgM fraction.", "content": "Rabbit anti rat lymphocyte serum: immunosuppression mediated by a pure IgM fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209178"} {"pmid": "4209181", "title": "An orthopantomographic study of developmental mandibular bone defects (Stafne's idiopathic bone cavities).", "content": "An orthopantomographic study of developmental mandibular bone defects (Stafne's idiopathic bone cavities).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209181"} {"pmid": "4209180", "title": "Relation between fragments after oblique sliding osteotomy of the mandibular rami and its influence on postoperative conditions.", "content": "Relation between fragments after oblique sliding osteotomy of the mandibular rami and its influence on postoperative conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209180"} {"pmid": "4209183", "title": "The relationship between hyphal branching, specific growth rate and colony radial growth rate in Penicillium chrysogenum.", "content": "The relationship between hyphal branching, specific growth rate and colony radial growth rate in Penicillium chrysogenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209183"} {"pmid": "4209179", "title": "Cellular and humoral pathways in the neuroendocrine regulation of reproductive function.", "content": "Cellular and humoral pathways in the neuroendocrine regulation of reproductive function. Studies carried out in recent years, including those conducted by the author on the rhesus monkey, which have added more information on the possible cellular and humoral pathways by which the neural and endocrine functions concerned with reproductive phenomena are integrated are reviewed. The possible involvement of the circumventricular structures, especially the tanycyte ependyma and the pineal gland in the detection of the endogenous levels of gonadal hormones, and the cerebrospinal fluid (CSF) in the transmission of hormonal information to the various parts of the brain indicated further areas of research to be explored. Such exploration should be conducted in diverse, yet complimentary, disciplines so that the whole spectrum of events known to occur in the neuroendocrine regulation of reproduction can be studied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209179"} {"pmid": "4209184", "title": "Editorial: Coming of age of medical primatology.", "content": "Editorial: Coming of age of medical primatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209184"} {"pmid": "4209174", "title": "The role of calcium for stability and activity of an extracellular proteolytic enzyme from Staphylococcus aureus.", "content": "The role of calcium for stability and activity of an extracellular proteolytic enzyme from Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209174"} {"pmid": "4209187", "title": "Comparative study of radiosensitivity of peripheral blood lymphocyte chromosomes of Macaca mulatta at different doses of irradiation.", "content": "Comparative study of radiosensitivity of peripheral blood lymphocyte chromosomes of Macaca mulatta at different doses of irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209187"} {"pmid": "4209186", "title": "Blood groups of mountain gorillas (Gorilla gorilla beringei).", "content": "Blood groups of mountain gorillas (Gorilla gorilla beringei).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209186"} {"pmid": "4209188", "title": "Ultrastructural observations on scrapie in the gerbil.", "content": "Ultrastructural observations on scrapie in the gerbil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209188"} {"pmid": "4209189", "title": "Inoculation of cattle with bovine lymphoid cell lines infected with Theileria annulata.", "content": "Inoculation of cattle with bovine lymphoid cell lines infected with Theileria annulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209189"} {"pmid": "4209185", "title": "Studies on menstrual blood loss in intact and experimental rhesus monkeys.", "content": "Studies on menstrual blood loss in intact and experimental rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209185"} {"pmid": "4209190", "title": "African swine fever: comparison of four serotests on porcine serums in Spain.", "content": "African swine fever: comparison of four serotests on porcine serums in Spain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209190"} {"pmid": "4209193", "title": "Woodruffia metabolica: an exception to the rule of desmodexy.", "content": "Woodruffia metabolica: an exception to the rule of desmodexy. Woodruffia metabolica (Protozoa, Ciliophora) has a compound fiber on the left side of its ciliary rows composed of parallel, overlapping ribbons of kinetosome-based microtubules. No similar structure is found connecting the kinetosomes on the right side of the ciliary rows. This arrangement is in opposition to the rule of desmodexy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209193"} {"pmid": "4209194", "title": "To the possible spread of scabies through bed linen.", "content": "To the possible spread of scabies through bed linen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209194"} {"pmid": "4209195", "title": "Pair formation in tetrahymena pyriformis, an inducible developmental system.", "content": "Pair formation in tetrahymena pyriformis, an inducible developmental system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209195"} {"pmid": "4209196", "title": "Glycogen synthetase and phosphorylase in developing chick glycogen body.", "content": "Glycogen synthetase and phosphorylase in developing chick glycogen body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209196"} {"pmid": "4209199", "title": "Community health education: a challenge to hospital and medical staffs.", "content": "Community health education: a challenge to hospital and medical staffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209199"} {"pmid": "4209182", "title": "The composition of several commercial rapid tube and saline anti-D reagents.", "content": "The composition of several commercial rapid tube and saline anti-D reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209182"} {"pmid": "4209201", "title": "Immunologic reactivity in rabbits remotely deprived of the sacculus rotundus.", "content": "Immunologic reactivity in rabbits remotely deprived of the sacculus rotundus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209201"} {"pmid": "4209202", "title": "Conductance of active and passive pathways in the toad bladder.", "content": "Conductance of active and passive pathways in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209202"} {"pmid": "4209203", "title": "Aldosterone stimulation of acidification of urine by isolated urinary bladder of the Colombian toad.", "content": "Aldosterone stimulation of acidification of urine by isolated urinary bladder of the Colombian toad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209203"} {"pmid": "4209204", "title": "Evolution of a facilitated diffusion pathway for amides in the erythrocyte.", "content": "Evolution of a facilitated diffusion pathway for amides in the erythrocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209204"} {"pmid": "4209200", "title": "Control of cell division in bacteria.", "content": "Control of cell division in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209200"} {"pmid": "4209205", "title": "Stimulation by amphotericin B of active Na transport across amphibian cornea.", "content": "Stimulation by amphotericin B of active Na transport across amphibian cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209205"} {"pmid": "4209206", "title": "Spatial distribution of human cell survival and oxygen effect in a therapeutic helium ion beam.", "content": "Spatial distribution of human cell survival and oxygen effect in a therapeutic helium ion beam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209206"} {"pmid": "4209207", "title": "ISAH: a versatile treatment positioner for external radiation therapy.", "content": "ISAH: a versatile treatment positioner for external radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209207"} {"pmid": "4209210", "title": "Radiation therapy of Hodgkin's disease: significance of splenic involvement.", "content": "Radiation therapy of Hodgkin's disease: significance of splenic involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209210"} {"pmid": "4209208", "title": "Spatial distribution of human cell survival in a neutron bean designed for therapy.", "content": "Spatial distribution of human cell survival in a neutron bean designed for therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209208"} {"pmid": "4209211", "title": "Theoretical explanations of drug-dissociated behaviors.", "content": "Theoretical explanations of drug-dissociated behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209211"} {"pmid": "4209212", "title": "Hallucinogens as discriminative stimuli.", "content": "Hallucinogens as discriminative stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209212"} {"pmid": "4209209", "title": "Experience with fast neutron therapy usine the Texas A and M variable energy cyclotron.", "content": "Experience with fast neutron therapy usine the Texas A and M variable energy cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209209"} {"pmid": "4209213", "title": "Experimental inhibition of serotonin by antibiotic: prevention of cerebral vasospasm.", "content": "Experimental inhibition of serotonin by antibiotic: prevention of cerebral vasospasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209213"} {"pmid": "4209217", "title": "Continuous nasogastric infusion feedings of infants of low birth weight.", "content": "Continuous nasogastric infusion feedings of infants of low birth weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209217"} {"pmid": "4209218", "title": "Feeding the low birth weight infant: orally or parenterally? Preliminary results of a comparative study.", "content": "Feeding the low birth weight infant: orally or parenterally? Preliminary results of a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209218"} {"pmid": "4209219", "title": "Prenatal diagnosis and selective abortion for anencephaly and spina bifida.", "content": "Prenatal diagnosis and selective abortion for anencephaly and spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209219"} {"pmid": "4209220", "title": "Simple method for detecting amylase inhibitors in biological materials.", "content": "Simple method for detecting amylase inhibitors in biological materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209220"} {"pmid": "4209221", "title": "Interferon response of the fetal Rhesus monkey after viral infection.", "content": "Interferon response of the fetal Rhesus monkey after viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209221"} {"pmid": "4209215", "title": "Proceedings: 320. Visuokinetic neurons of the prefrontal cortex and delayed response.", "content": "Proceedings: 320. Visuokinetic neurons of the prefrontal cortex and delayed response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209215"} {"pmid": "4209214", "title": "Proceedings: 314. Group I activated neurons of 3a area and voluntary forearm movement in the monkey.", "content": "Proceedings: 314. Group I activated neurons of 3a area and voluntary forearm movement in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209214"} {"pmid": "4209216", "title": "Proceedings: 362. Response of the amphibian papilla nerve in the toad bufomarinus.", "content": "Proceedings: 362. Response of the amphibian papilla nerve in the toad bufomarinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209216"} {"pmid": "4209222", "title": "Surface pattern of some microsporidian spores as seen in the scanning electron microscope.", "content": "Surface pattern of some microsporidian spores as seen in the scanning electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209222"} {"pmid": "4209224", "title": "Effects of age on the susceptibility of larvae and nymphs of Ixodes ricinus (L.) to insecticides.", "content": "Effects of age on the susceptibility of larvae and nymphs of Ixodes ricinus (L.) to insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209224"} {"pmid": "4209223", "title": "The protozoan flora of potable water from natural sources and its sub-clinical implications.", "content": "The protozoan flora of potable water from natural sources and its sub-clinical implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209223"} {"pmid": "4209227", "title": "Nitrogen metabolism and ultrastructure in Anabaena cylindrica. I. The effect of nitrogen starvation.", "content": "Nitrogen metabolism and ultrastructure in Anabaena cylindrica. I. The effect of nitrogen starvation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209227"} {"pmid": "4209225", "title": "Bladder diverticula in infants and children.", "content": "Bladder diverticula in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209225"} {"pmid": "4209226", "title": "High pressure voiding urethrography. Principle and technique.", "content": "High pressure voiding urethrography. Principle and technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209226"} {"pmid": "4209228", "title": "Photochemical disproportionation of sulfur into sulfide and sulfate by Chlorobium limicola forma thiosulfatophilum.", "content": "Photochemical disproportionation of sulfur into sulfide and sulfate by Chlorobium limicola forma thiosulfatophilum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209228"} {"pmid": "4209234", "title": "Prolactin and mental illness.", "content": "Prolactin and mental illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209234"} {"pmid": "4209235", "title": "A Welsh forensic psychiatric service for doctors.", "content": "A Welsh forensic psychiatric service for doctors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209235"} {"pmid": "4209237", "title": "Oculofacial anomalies and corneal ulceration.", "content": "Oculofacial anomalies and corneal ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209237"} {"pmid": "4209238", "title": "rDNA magnification at the bobbed locus of the Y chromosome in Drosophila melanogaster.", "content": "rDNA magnification at the bobbed locus of the Y chromosome in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209238"} {"pmid": "4209244", "title": "Management of depressed fractures of the skull.", "content": "Management of depressed fractures of the skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209244"} {"pmid": "4209243", "title": "Protein-calorie malnutrition in Fiji (a clinical survey of malnourished children, admitted to the Colonial War Memorial Hospital, Suva).", "content": "Protein-calorie malnutrition in Fiji (a clinical survey of malnourished children, admitted to the Colonial War Memorial Hospital, Suva).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209243"} {"pmid": "4209245", "title": "Aeruginocin tolerant mutants of Pseudomonas aeruginosa.", "content": "Aeruginocin tolerant mutants of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209245"} {"pmid": "4209247", "title": "Beta2-microglobulin: occurrence in fetal life and malignancy.", "content": "Beta2-microglobulin: occurrence in fetal life and malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209247"} {"pmid": "4209248", "title": "Evidence for membrane cholesterol as the common binding site for cereolysin, streptolysin O and saponin.", "content": "Evidence for membrane cholesterol as the common binding site for cereolysin, streptolysin O and saponin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209248"} {"pmid": "4209249", "title": "Metallic copper as an intrauterine contraceptive agent.", "content": "Metallic copper as an intrauterine contraceptive agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209249"} {"pmid": "4209254", "title": "Vasopressin release from the isolated neurohypophysis induced by a calcium ionophore, X-537A.", "content": "Vasopressin release from the isolated neurohypophysis induced by a calcium ionophore, X-537A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209254"} {"pmid": "4209256", "title": "An evaluation of 1-(4-methyl) 2, 5-dimethoxyphenyl-2-aminobutane (MDPA-1) as an enhancer of memory and learning.", "content": "An evaluation of 1-(4-methyl) 2, 5-dimethoxyphenyl-2-aminobutane (MDPA-1) as an enhancer of memory and learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209256"} {"pmid": "4209257", "title": "Prolonged parenteral nutrition in the home.", "content": "Prolonged parenteral nutrition in the home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209257"} {"pmid": "4209258", "title": "Fatty acid-induced tuberculocidal activity in sera of guinea pigs treated with bacillus Calmette-Guérin and lipopolysaccharide.", "content": "Fatty acid-induced tuberculocidal activity in sera of guinea pigs treated with bacillus Calmette-Guérin and lipopolysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209258"} {"pmid": "4209259", "title": "The small intestinal lesion induced by Hawaii agent acute infectious nonbacterial gastroenteritis.", "content": "The small intestinal lesion induced by Hawaii agent acute infectious nonbacterial gastroenteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209259"} {"pmid": "4209261", "title": "Chemistry and enzymology of kcat inhibitors.", "content": "Chemistry and enzymology of kcat inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209261"} {"pmid": "4209260", "title": "Fetal malnutrition.", "content": "Fetal malnutrition. Fetal malnutrition has been associated with maturational defect in cell metabolism. A series of studies on anthropometric and clinical aspects of patients with intrauterine malnutrition was conducted to establish the relationship between intrauterine growth failure and cell function. The 1st study assessed intrauterine growth in 128 cases. 36 infants were found to be small for gestational age and exhibited usual signs of fetal growth retardation. The mothers of these infants were similar with respect to age, weight, height, nutritional patterns, and prior pregnancy histories. The 2nd study determined whether there was a unique pattern for certain cell energy function in leukocytes of mothers and their small-for-gestational age infants at the time of birth, and whether this pattern was the same as that found in infants with severe postnatal protein-calorie malnutrition. The findings showed that the altered pattern of energy metabolism in leukocytes of infants with intrauterine growth retardation was the same as that found in young infants with postnatal protein-calorie malnutrition. The similarity of enzyme pattern in the adenine nucleotide contents of maternal and cord blood leukocytes at time of delivery also supported the interrelationship between energy metabolisms of mothers and their fetuses. The 3rd study suggested that fetal malnutrition may be reflected in placental tissues. These studies may prove useful in developing diagnostic tools for monitoring fetal growth and for establishing criteria for intervention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209260"} {"pmid": "4209263", "title": "A thin, flat, parallel plate ionization chamber for electron beam depth-dose measurements.", "content": "A thin, flat, parallel plate ionization chamber for electron beam depth-dose measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209263"} {"pmid": "4209262", "title": "Methylmalonic acid excretion studies.", "content": "Methylmalonic acid excretion studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209262"} {"pmid": "4209264", "title": "Histones of Drosophila embryos. Electrophoretic isolation and structural studies.", "content": "Histones of Drosophila embryos. Electrophoretic isolation and structural studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209264"} {"pmid": "4209265", "title": "Activation of succinate dehydrogenase by FMNH2 and by photoreduction.", "content": "Activation of succinate dehydrogenase by FMNH2 and by photoreduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209265"} {"pmid": "4209268", "title": "Trimethoprim-sensitivity testing and thymineless mutants.", "content": "Trimethoprim-sensitivity testing and thymineless mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209268"} {"pmid": "4209267", "title": "Site of attachment of J chain to human immunoglobulin M.", "content": "Site of attachment of J chain to human immunoglobulin M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209267"} {"pmid": "4209266", "title": "Role of myosin light chains in calcium regulation.", "content": "Role of myosin light chains in calcium regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209266"} {"pmid": "4209269", "title": "Partial characterisation of Escherichia coli haemolysin.", "content": "Partial characterisation of Escherichia coli haemolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209269"} {"pmid": "4209270", "title": "Diagnosis of subacute sclerosing panencephalitis by serial tissue co-cultivation.", "content": "Diagnosis of subacute sclerosing panencephalitis by serial tissue co-cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209270"} {"pmid": "4209271", "title": "Thyrotropin-releasing hormone: regional distribution in rat brain.", "content": "Thyrotropin-releasing hormone: regional distribution in rat brain. A sensitive and specific radioimmnunoassay has been used to measure the distribution of thyrotropin-releasing hormone (TRH) in rat brain. All areas of brain tested, except cerebellum, contained readily measurable amounts of TRH. The hypothalamus contained only 31.2 percent of the total brain content of TRH. These results support recent suggestions of central actions for TRH in addition to its hypophysiotropic functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209271"} {"pmid": "4209272", "title": "Thyrotropin-releasing hormone in specific nuclei of rat brain.", "content": "Thyrotropin-releasing hormone in specific nuclei of rat brain. The regional distribution of thyrotropin-releasing hormone (TRH) in rat brain was studied. The greatest concentration of TRH was found in the median eminence. High concentrations were also found in several hypothalamic nuclei. Outside the hypothalamus, relatively large amounts of TRH were found in the septal and preoptic areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209272"} {"pmid": "4209273", "title": "Symptomatic arachnoid diverticula.", "content": "Symptomatic arachnoid diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209273"} {"pmid": "4209274", "title": "Periventricular leukoencephalopathy in the monkey. A search for the \"normal control\" and the \"early lesion\".", "content": "Periventricular leukoencephalopathy in the monkey. A search for the \"normal control\" and the \"early lesion\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209274"} {"pmid": "4209276", "title": "The nature of Encephalitozoon brumpti Coulon, 1924.", "content": "The nature of Encephalitozoon brumpti Coulon, 1924.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209276"} {"pmid": "4209275", "title": "Hypothalamic releasing factors and Parkinson disease.", "content": "Hypothalamic releasing factors and Parkinson disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209275"} {"pmid": "4209277", "title": "Effects of L-tryptophan, L-3, 4, dihydroxyphenylalanine and tranylcypromine on the electroencephalogram and on photically induced epilepsy in the baboon, Papio papio.", "content": "Effects of L-tryptophan, L-3, 4, dihydroxyphenylalanine and tranylcypromine on the electroencephalogram and on photically induced epilepsy in the baboon, Papio papio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209277"} {"pmid": "4209279", "title": "Rebound eating following carbachol-induced drinking in rats.", "content": "Rebound eating following carbachol-induced drinking in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209279"} {"pmid": "4209278", "title": "Equine infectious anemia.", "content": "Equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209278"} {"pmid": "4209280", "title": "A contact detection system for identifying individual animals in groups.", "content": "A contact detection system for identifying individual animals in groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209280"} {"pmid": "4209281", "title": "Activities of DNA degrading enzymes in the slime mold Physarum polycephalum. Evidence for five different enzymes.", "content": "Activities of DNA degrading enzymes in the slime mold Physarum polycephalum. Evidence for five different enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209281"} {"pmid": "4209282", "title": "The effect of fixation on the wave propagation of the protozoan axostyle.", "content": "The effect of fixation on the wave propagation of the protozoan axostyle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209282"} {"pmid": "4209283", "title": "Utile and futile cycles in the liver.", "content": "Utile and futile cycles in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209283"} {"pmid": "4209285", "title": "Are segments of chloroplast DNA differentially amplified?", "content": "Are segments of chloroplast DNA differentially amplified?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209285"} {"pmid": "4209284", "title": "Enhanced specificity of epinephrine binding by rat liver plasma membranes in the presence of EDTA.", "content": "Enhanced specificity of epinephrine binding by rat liver plasma membranes in the presence of EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209284"} {"pmid": "4209286", "title": "Calcium ion regulation of flagellar beat symmetry in reactivated sea urchin spermatozoa.", "content": "Calcium ion regulation of flagellar beat symmetry in reactivated sea urchin spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209286"} {"pmid": "4209287", "title": "Ultrastructural localization of cell wall teichoic acids in Streptococcus faecalis by means of concanavalin A.", "content": "Ultrastructural localization of cell wall teichoic acids in Streptococcus faecalis by means of concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209287"} {"pmid": "4209289", "title": "The basic nuclear proteins of the cellular slime mold Dictyostelium discoideum.", "content": "The basic nuclear proteins of the cellular slime mold Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209289"} {"pmid": "4209291", "title": "Lung contamination by Ce and La. Evolution of the early spontaneous absorption as a function of the initial lung burden.", "content": "Lung contamination by Ce and La. Evolution of the early spontaneous absorption as a function of the initial lung burden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209291"} {"pmid": "4209288", "title": "The influence of EDTA on the composition of alginate synthesized by Azotobacter vinelandii.", "content": "The influence of EDTA on the composition of alginate synthesized by Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209288"} {"pmid": "4209292", "title": "Retention of inhaled antimony-124 in the beagle dog as a function of temperature of aerosol formation.", "content": "Retention of inhaled antimony-124 in the beagle dog as a function of temperature of aerosol formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209292"} {"pmid": "4209293", "title": "Investigations on radiosensitive and radioresistant populations of Drosophila melanogaster. IV. The genetics of the relative radioresistance in stage-7 oocytes of the irradiated population RO I.", "content": "Investigations on radiosensitive and radioresistant populations of Drosophila melanogaster. IV. The genetics of the relative radioresistance in stage-7 oocytes of the irradiated population RO I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209293"} {"pmid": "4209294", "title": "The induction of aneuploidy by colcemid fed to Drosophila melanogaster females.", "content": "The induction of aneuploidy by colcemid fed to Drosophila melanogaster females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209294"} {"pmid": "4209295", "title": "Heterologous interchange and non-disjunction of distributively paired chromosomes in Drosophila melanogaster: immature oocytes.", "content": "Heterologous interchange and non-disjunction of distributively paired chromosomes in Drosophila melanogaster: immature oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209295"} {"pmid": "4209296", "title": "Genetically significant dose from beam therapy in Japan, 1971.", "content": "Genetically significant dose from beam therapy in Japan, 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209296"} {"pmid": "4209297", "title": "Growth of surface colonies of the gliding bacterium Myxococcus xanthus.", "content": "Growth of surface colonies of the gliding bacterium Myxococcus xanthus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209297"} {"pmid": "4209298", "title": "Participation of two photosystems in the photo-phobotaxis of Phormidium uncinatum.", "content": "Participation of two photosystems in the photo-phobotaxis of Phormidium uncinatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209298"} {"pmid": "4209301", "title": "The reproductive cycle of the gelada baboon.", "content": "The reproductive cycle of the gelada baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209301"} {"pmid": "4209300", "title": "Ozone effects on chlorophylls a and b.", "content": "Ozone effects on chlorophylls a and b.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209300"} {"pmid": "4209299", "title": "Indentification of a pH 6.5 acetohydroxyacid synthetase in Bacillus subtilis.", "content": "Indentification of a pH 6.5 acetohydroxyacid synthetase in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209299"} {"pmid": "4209306", "title": "Tobacco budworm: chemosterilization by fumigation with thiotepa.", "content": "Tobacco budworm: chemosterilization by fumigation with thiotepa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209306"} {"pmid": "4209307", "title": "Corynebacterium diphtheriae infections in Tanzania.", "content": "Corynebacterium diphtheriae infections in Tanzania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209307"} {"pmid": "4209308", "title": "Immunisation of marmoset monkeys with a killed oncogenic herpesvirus.", "content": "Immunisation of marmoset monkeys with a killed oncogenic herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209308"} {"pmid": "4209311", "title": "Effect of anti-C4 on cellular synthesis of C4 by guinea pig peritoneal macrophages, pulmonary macrophages, liver or spleen cells.", "content": "Effect of anti-C4 on cellular synthesis of C4 by guinea pig peritoneal macrophages, pulmonary macrophages, liver or spleen cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209311"} {"pmid": "4209310", "title": "Intraluminal duodenal diverticulum.", "content": "Intraluminal duodenal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209310"} {"pmid": "4209314", "title": "Preparation of penicillin N and isopenicillin N.", "content": "Preparation of penicillin N and isopenicillin N.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209314"} {"pmid": "4209312", "title": "Isolation and properties of recombination-deficient mutants of Pseudomonas aeruginosa.", "content": "Isolation and properties of recombination-deficient mutants of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209312"} {"pmid": "4209313", "title": "Localization of chemically induced breaks in chromosomes of human leucocytes.", "content": "Localization of chemically induced breaks in chromosomes of human leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209313"} {"pmid": "4209315", "title": "Recent studies on the origins of cellular organelles.", "content": "Recent studies on the origins of cellular organelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209315"} {"pmid": "4209316", "title": "Studies of ribosomal diffusion coefficients using laser light-scattering spectroscopy.", "content": "Studies of ribosomal diffusion coefficients using laser light-scattering spectroscopy. Using an optical beating technique, the diffusion coefficients and relative scattered intensity of Escherichia coli 70S, 50S, and 30S ribosomes are measured as a function of temperature and Mg(2+) concentration. For solutions at 10 mM Mg(2+) and between 0 degrees C and about 40 degrees C, the values of D(20,w) obtained are 1.7, 1.9, and approximately 2.1 x 10(-7) cm(2)/s, respectively. Preparative procedures drastically affect these values and equivalent hydrodynamic ellipsoids of revolution models give large axial ratios indicating extensive hydration or a deviation from the assumed shape. Calculations also indicate that the subunits expand upon dissociation. Measurements of D(20,w) vs. temperature indicate that 70S particles undergo a conformational change prior to dissociation and can be heat dissociated at 30-32 degrees C at low concentrations. Treatment of 70S ribosomes with EDTA causes a biphasic dissociation reaction. Addition of Mg(2+) after dissociation with EDTA shows that longer waiting times yield fewer 70S particles and that even short waiting times may yield ribosomes differing from the native conformation. Addition of p-chloromercuribenzoic acid (PCMB) is shown to dissociate 70S particles, but to a lesser extent than ethylenediaminetetraacetic acid (EDTA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209316"} {"pmid": "4209318", "title": "Glucose-6-phosphate dehydrogenase Jackson. A new variant associated with hemolytic anemia.", "content": "Glucose-6-phosphate dehydrogenase Jackson. A new variant associated with hemolytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209318"} {"pmid": "4209317", "title": "Serologic recognition of the histocompatibility antigens using agglutination and cytotoxicity techniques.", "content": "Serologic recognition of the histocompatibility antigens using agglutination and cytotoxicity techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209317"} {"pmid": "4209321", "title": "Complement-mediated changes in morphology of hepatitis B antigen-antibody complexes.", "content": "Complement-mediated changes in morphology of hepatitis B antigen-antibody complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209321"} {"pmid": "4209319", "title": "Cell wall alterations of gram-negative bacteria by aminoglycoside antibiotics.", "content": "Cell wall alterations of gram-negative bacteria by aminoglycoside antibiotics. After treatment with aminoglycoside antibiotics, Escherichia coli B and Pseudomonas aeruginosa P28 showed numerous blebs on the cell wall surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209319"} {"pmid": "4209322", "title": "Differences between Bombay and Rhnull phenotypes.", "content": "Differences between Bombay and Rhnull phenotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209322"} {"pmid": "4209323", "title": "Time-related changes in reaction determining hepatitis B antigen in viral hepatitis patients.", "content": "Time-related changes in reaction determining hepatitis B antigen in viral hepatitis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209323"} {"pmid": "4209324", "title": "Differentiation of Drosophila neuroblasts to form ganglion-like clusters of neurons in vitro.", "content": "Differentiation of Drosophila neuroblasts to form ganglion-like clusters of neurons in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209324"} {"pmid": "4209325", "title": "The effect of humoral agents on the cranial circulation of the monkey.", "content": "The effect of humoral agents on the cranial circulation of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209325"} {"pmid": "4209326", "title": "In vitro immunological characteristics of lymphoid cells derived from owl monkeys infected with Herpesvirus saimiri.", "content": "In vitro immunological characteristics of lymphoid cells derived from owl monkeys infected with Herpesvirus saimiri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209326"} {"pmid": "4209327", "title": "Immunological and virological investigations on owl monkeys infected with Herpesvirus saimiri.", "content": "Immunological and virological investigations on owl monkeys infected with Herpesvirus saimiri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209327"} {"pmid": "4209328", "title": "Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey.", "content": "Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209328"} {"pmid": "4209329", "title": "Specificity differentiation (SPD) of oncogenic and non-oncogenic herpesviruses by immunofluorescence.", "content": "Specificity differentiation (SPD) of oncogenic and non-oncogenic herpesviruses by immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209329"} {"pmid": "4209330", "title": "Immunochemical quantitation of dextran by a polymer enhanced nephelometric procedure.", "content": "Immunochemical quantitation of dextran by a polymer enhanced nephelometric procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209330"} {"pmid": "4209331", "title": "Cortisone-resistant thymocytes as target cells in lymphocyte-mediated cytolysis.", "content": "Cortisone-resistant thymocytes as target cells in lymphocyte-mediated cytolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209331"} {"pmid": "4209332", "title": "Iron absorption from maize. Effect of ascorbic acid on iron absorption from maize supplemented with ferrous sulphate.", "content": "Iron absorption from maize. Effect of ascorbic acid on iron absorption from maize supplemented with ferrous sulphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209332"} {"pmid": "4209334", "title": "The effects of orbital and dorsolateral frontal cortical ablations on ethanol self-selection and emotional behaviors in monkeys (Macaca nemestrina).", "content": "The effects of orbital and dorsolateral frontal cortical ablations on ethanol self-selection and emotional behaviors in monkeys (Macaca nemestrina).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209334"} {"pmid": "4209333", "title": "Detection of brief light flashes by monkeys (Macaca nemestrina) with dorsolateral frontal ablations.", "content": "Detection of brief light flashes by monkeys (Macaca nemestrina) with dorsolateral frontal ablations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209333"} {"pmid": "4209348", "title": "Membrane-bound DD-carboxypeptidase and LD-transpeptidase of Streptococcus faecalis ATCC 9790.", "content": "Membrane-bound DD-carboxypeptidase and LD-transpeptidase of Streptococcus faecalis ATCC 9790.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209348"} {"pmid": "4209347", "title": "Composition of lipopolysaccharides from Myxococcus fulvus and other fruiting and non-fruiting myxobacteria.", "content": "Composition of lipopolysaccharides from Myxococcus fulvus and other fruiting and non-fruiting myxobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209347"} {"pmid": "4209350", "title": "Reactive hyperaemia in the dog heart: studies on mechanisms.", "content": "Reactive hyperaemia in the dog heart: studies on mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209350"} {"pmid": "4209352", "title": "Mutagenicity of reactive derivatives of carcinogenic hydrocarbons: evidence of DNA repair.", "content": "Mutagenicity of reactive derivatives of carcinogenic hydrocarbons: evidence of DNA repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209352"} {"pmid": "4209349", "title": "Some kinetic properties of human-milk galactosyl transferase.", "content": "Some kinetic properties of human-milk galactosyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209349"} {"pmid": "4209353", "title": "Pathogenesis of anemia associated with Mycoplasma pneumoniae.", "content": "Pathogenesis of anemia associated with Mycoplasma pneumoniae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209353"} {"pmid": "4209354", "title": "Bilateral ossification of the ear canal in an American Cocker Spaniel.", "content": "Bilateral ossification of the ear canal in an American Cocker Spaniel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209354"} {"pmid": "4209357", "title": "The immunology of experimental Chagas' disease. 3. Rejection of allogeneic heart cells in vitro.", "content": "The immunology of experimental Chagas' disease. 3. Rejection of allogeneic heart cells in vitro. Experiments that consisted of incubation of Trypanosoma cruzi-sensitized lymphocytes derived from chronically infected rabbits and from rabbits repeatedly immunized with a small particle or membrane fraction derived from homogenates of T. cruzi forms, showed destruction of allogeneic, parasitized and nonparasitized heart cells in vitro. Mononuclear cells collected from peripheral blood were incubated for 1 h at 37 degrees C to isolate the lymphocytes. Following incubation, over 99% of the cells in the supernate were lymphocytes, which were utilized in these experiments. At the start of these experiments, 70-80% of the sensitized lymphocytes were unattached, small and round, with sparse filipodia. In the ensuing hours, marked heart cell destruction, similar to that seen in an active lesion when lymphocytes invade heart tissue, were observed. After 18 h incubation, about 65-70% of the lymphocytes were attached, larger, and rough surfaced. Inhibition of monocyte migration tests, each in the presence of the antigens of subcellular fractions of T. cruzi organisms and of allogeneic heart myofibers, indicated the presence of a cross-reacting antigen common to both the parasite and the heart in the small particle or membrane fractions. The particulate antigens of the 30,000 g, 35-min fraction of heart muscle gave rise to inhibition of monocyte migration as did the counterpart fraction derived from T. cruzi organisms. The destruction of nonparasitized target heart cells by T. cruzi-sensitized lymphocytes is an in vitro model of the chronic myocarditis of Chagas' disease, and the recognition of cross-reactive antigens of the host cell by T. cruzi-sensitized lymphocytes is believed to be the pathogenic basis for subsequent tissue injury in the chronic phase of this disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209357"} {"pmid": "4209358", "title": "Role of meningococcal endotoxin in meningococcal purpura.", "content": "Role of meningococcal endotoxin in meningococcal purpura. Enteric bacilli and meningococci (MGC) both contain potent endotoxins, but purpuric skin lesions indistinguishable from the experimental dermal Shwartzman reaction are much more common during meningococcal bacteremia than during bacteremia with enteric organisms. Highly purified lipopolysaccharides (LPS), virtually free of contamination by protein, RNA, and capsule, were extracted by a modification of the phenol-water technique from MGC (serogroups A, B, and C) and enteric bacilli (Escherichia coli 04 and 0:111, and Salmonella typhimurium). Polysaccharides in these LPS were similar by gas chromatography except for one galactose-deficient strain of MGC (135B). LPS from MGC and enterics were equally potent for the general Shwartzman reaction and mouse lethality, but LPS from MGC was 5-10 times more potent in inducing the dermal Shwartzman reaction. The greater skin potency of LPS from MGC explains the prominence of purpura in meningococcemia. Comparison of the properties of LPS may explain other differences in clinical syndromes caused by gram-negative bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209358"} {"pmid": "4209359", "title": "Restoration of mycolate synthetase activity in Mycobacterium tuberculosis exposed to isoniazid.", "content": "Restoration of mycolate synthetase activity in Mycobacterium tuberculosis exposed to isoniazid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209359"} {"pmid": "4209362", "title": "Niacin-negative Mycobacterium tuberculosis.", "content": "Niacin-negative Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209362"} {"pmid": "4209360", "title": "Primary drug resistance: a continuing study of drug resistance in tuberculosis in a veteran population within the United States. X. September 1970 to September 1973.", "content": "Primary drug resistance: a continuing study of drug resistance in tuberculosis in a veteran population within the United States. X. September 1970 to September 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209360"} {"pmid": "4209361", "title": "Primary drug resistance in children. Drug susceptibility of strains of M. tuberculosis isolated from children during the years 1969 to 1972 at the Kings County Hospital Medical Center of Brooklyn.", "content": "Primary drug resistance in children. Drug susceptibility of strains of M. tuberculosis isolated from children during the years 1969 to 1972 at the Kings County Hospital Medical Center of Brooklyn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209361"} {"pmid": "4209363", "title": "Letter: Protein calorie malnutrition, gastric motility and diabetes.", "content": "Letter: Protein calorie malnutrition, gastric motility and diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209363"} {"pmid": "4209365", "title": "Evidence for cellular control in the synthesis of acetoin or alpha-ketoisovaleric acid by microorganisms.", "content": "Evidence for cellular control in the synthesis of acetoin or alpha-ketoisovaleric acid by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209365"} {"pmid": "4209367", "title": "The influence of culture conditions on the antigenic products of Saprolegnia.", "content": "The influence of culture conditions on the antigenic products of Saprolegnia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209367"} {"pmid": "4209355", "title": "A rapid method for estimating microsomal oxidase activity in the housefly with (14C)parathion as substrate.", "content": "A rapid method for estimating microsomal oxidase activity in the housefly with (14C)parathion as substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209355"} {"pmid": "4209372", "title": "Immunoglobulin abnormalities in multiple sclerosis.", "content": "Immunoglobulin abnormalities in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209372"} {"pmid": "4209369", "title": "Levels of serum immunoglobulins in juvenile rheumatoid arthritis.", "content": "Levels of serum immunoglobulins in juvenile rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209369"} {"pmid": "4209370", "title": "Similarities between the scrapie agent and the agent of the potato spindle tuber disease.", "content": "Similarities between the scrapie agent and the agent of the potato spindle tuber disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209370"} {"pmid": "4209374", "title": "Longterm clinical study with glibenclamide.", "content": "Longterm clinical study with glibenclamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209374"} {"pmid": "4209371", "title": "Properties of SSPE virus; tissue culture and animal studies.", "content": "Properties of SSPE virus; tissue culture and animal studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209371"} {"pmid": "4209380", "title": "Isolation of Trypanosoma cruzi in an acutely infected patient.", "content": "Isolation of Trypanosoma cruzi in an acutely infected patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209380"} {"pmid": "4209375", "title": "Editorial: Of what measures are second generation suphonylureas?", "content": "Editorial: Of what measures are second generation suphonylureas?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209375"} {"pmid": "4209379", "title": "Whole-body counting: analysis of retention data for isotopes having prominent fecal excretion.", "content": "Whole-body counting: analysis of retention data for isotopes having prominent fecal excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209379"} {"pmid": "4209381", "title": "A method for counting and concentrating living Trypanosoma cruzi in blood lysed with ammonium chloride.", "content": "A method for counting and concentrating living Trypanosoma cruzi in blood lysed with ammonium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209381"} {"pmid": "4209382", "title": "Immunity to Eimeria maxima: reactions of antisera in vitro and protection in vivo.", "content": "Immunity to Eimeria maxima: reactions of antisera in vitro and protection in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209382"} {"pmid": "4209378", "title": "Immunological and biochemical studies on fractionated bull spermatozoa.", "content": "Immunological and biochemical studies on fractionated bull spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209378"} {"pmid": "4209383", "title": "Immunoglobulin levels in a laboratory-acquired case of human Chagas' disease.", "content": "Immunoglobulin levels in a laboratory-acquired case of human Chagas' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209383"} {"pmid": "4209384", "title": "Hematozoa from Colorado birds. IV. Galliformes.", "content": "Hematozoa from Colorado birds. IV. Galliformes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209384"} {"pmid": "4209388", "title": "Bacteriocinogeny in the Athiorhodaceae.", "content": "Bacteriocinogeny in the Athiorhodaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209388"} {"pmid": "4209385", "title": "A rapid method for the purification of immunoglobulin M (IgM) from the sera of certain mammalian species.", "content": "A rapid method for the purification of immunoglobulin M (IgM) from the sera of certain mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209385"} {"pmid": "4209386", "title": "Low grade osteomyelitis of the jaws-with actinomycosis.", "content": "Low grade osteomyelitis of the jaws-with actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209386"} {"pmid": "4209390", "title": "The radioallergosorbent test (RAST) in the diagnosis of atopic allergy.", "content": "The radioallergosorbent test (RAST) in the diagnosis of atopic allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209390"} {"pmid": "4209387", "title": "Adhesion of dextran to Streptococcus mutans.", "content": "Adhesion of dextran to Streptococcus mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209387"} {"pmid": "4209389", "title": "Evolution of reaginic antibodies in specific hyposensitization.", "content": "Evolution of reaginic antibodies in specific hyposensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209389"} {"pmid": "4209392", "title": "The relationship between blood coagulation and thrombosis and atherosclerosis in man, monkeys and carnivores.", "content": "The relationship between blood coagulation and thrombosis and atherosclerosis in man, monkeys and carnivores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209392"} {"pmid": "4209393", "title": "The effect of molecular iodine on platelet aggregation in vitro.", "content": "The effect of molecular iodine on platelet aggregation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209393"} {"pmid": "4209391", "title": "Immunological studies on the blood coagulation Factor X and its warfarin-induced precursor.", "content": "Immunological studies on the blood coagulation Factor X and its warfarin-induced precursor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209391"} {"pmid": "4209394", "title": "Some serum globulin changes in East Coast fever.", "content": "Some serum globulin changes in East Coast fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209394"} {"pmid": "4209395", "title": "Are all the Salmonella serological O factors polysaccharides?", "content": "Are all the Salmonella serological O factors polysaccharides?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209395"} {"pmid": "4209397", "title": "The cytogenetic analysis of a fractured gene in Drosophila.", "content": "The cytogenetic analysis of a fractured gene in Drosophila. The data presented in this study are derived from the analyses of Notch mutants known to be associated with visible cytological deficiencies. One mutant, Df(1)N(62b1), described as a right-side deficiency, bears a deletion that apparently initiates within the Notch locus and extends to the right as far as the locus of dm. Recombination experiments using heterozygotes of Df(1)N(62b1) with a series of intragenic point mutants within the Notch cistron suggest that this deficiency represents a deletion for the right-end portion of the gene. A consideration of the cytology of Df(1)N(62b1) supports the cytogenetic inference that, if a Notch locus-3C7 relationship is valid, the missing portion of the gene as assayed by recombination experiments has an interband position between 3C7 and 8.-The data derived from two left-side deficiencies with a genetic lesion in Notch and a deletion extending to w are somewhat equivocal, but they do support the presumed Notch locus-3C7 band relationship and thereby enhance the likelihood that Df(1)N(62b1) is correctly interpreted.-Cytogenetic information presently available suggests that, although a significant portion of the Notch cistron has a position on the salivary map identified as interband 3C7 to 8, the 3C7 band is part of the total picture of the Notch gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209397"} {"pmid": "4209398", "title": "Protein-calorie malnutrition diagnosis by hair tissue: a review.", "content": "Protein-calorie malnutrition diagnosis by hair tissue: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209398"} {"pmid": "4209401", "title": "A porcine immunoglobulin Fcmu polymer that has no J chain.", "content": "A porcine immunoglobulin Fcmu polymer that has no J chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209401"} {"pmid": "4209400", "title": "The subcellular distribution of 14C-glibenclamide in different tissues of rat.", "content": "The subcellular distribution of 14C-glibenclamide in different tissues of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209400"} {"pmid": "4209402", "title": "Characterization of the selenium in rat liver mitochondria as glutathione peroxidase.", "content": "Characterization of the selenium in rat liver mitochondria as glutathione peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209402"} {"pmid": "4209403", "title": "Purification of a hemagglutinin from Limulus polyphemus by affinity chromatography.", "content": "Purification of a hemagglutinin from Limulus polyphemus by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209403"} {"pmid": "4209404", "title": "A note on the use of reduced transport fluid (RTF) for isolation of Neisseria gonorrhoeae.", "content": "A note on the use of reduced transport fluid (RTF) for isolation of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209404"} {"pmid": "4209405", "title": "Susceptibility of mucoid Pseudomonas aeruginosa to gentamicin disks.", "content": "Susceptibility of mucoid Pseudomonas aeruginosa to gentamicin disks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209405"} {"pmid": "4209407", "title": "Letter: Somatostatin action on pancreas.", "content": "Letter: Somatostatin action on pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209407"} {"pmid": "4209406", "title": "The radiologist in prevention and diagnosis of instrumental perforation of the esophagus.", "content": "The radiologist in prevention and diagnosis of instrumental perforation of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209406"} {"pmid": "4209408", "title": "The alcohol dehydrogenases of Drosophila melanogaster: frequency changes associated with heat and cold shock.", "content": "The alcohol dehydrogenases of Drosophila melanogaster: frequency changes associated with heat and cold shock. Laboratory populations of Drosophila melanogaster were subjected to heat and cold shock of sufficient duration and intensity to cause about 90 percent mortality. Alcohol dehydrogenase phenotypes were determined in survivors and controls. Significant changes in phenotypic frequencies occurred as a result of both treatments such that relative fitness appeared to be dependent on temperature. The alcohol dehydrogenase phenotype most frequently surviving heat under laboratory conditions is the same phenotype as that previously found to be higher in frequency in natural populations in areas with higher average temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209408"} {"pmid": "4209409", "title": "Intracellular proteolytic activity in developing myxospores of Myxococcus xanthus.", "content": "Intracellular proteolytic activity in developing myxospores of Myxococcus xanthus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209409"} {"pmid": "4209413", "title": "Hematozoa of passeriform birds from insular Newfoundland.", "content": "Hematozoa of passeriform birds from insular Newfoundland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209413"} {"pmid": "4209414", "title": "Fissure sealants. Laboratory studies.", "content": "Fissure sealants. Laboratory studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209414"} {"pmid": "4209417", "title": "Blood groups in Zambia.", "content": "Blood groups in Zambia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209417"} {"pmid": "4209416", "title": "Population studies on the Aland Islands. II. Historical population structure: inference from bioassay of kinship and migration.", "content": "Population studies on the Aland Islands. II. Historical population structure: inference from bioassay of kinship and migration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209416"} {"pmid": "4209419", "title": "The selection for mutants in Drosophila melanogaster hypersensitive to alpha-methyl dopa, a dopa decarboxylase inhibitor.", "content": "The selection for mutants in Drosophila melanogaster hypersensitive to alpha-methyl dopa, a dopa decarboxylase inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209419"} {"pmid": "4209418", "title": "Identification of the structural gene of levansucrase in Bacillus subtilis Marburg.", "content": "Identification of the structural gene of levansucrase in Bacillus subtilis Marburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209418"} {"pmid": "4209420", "title": "Specific recognition in gene conversion. The extent of repair synthesis in SPP1 transfection of B. subtilis.", "content": "Specific recognition in gene conversion. The extent of repair synthesis in SPP1 transfection of B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209420"} {"pmid": "4209421", "title": "A technique for isolating the enamel organ of the rat incisor for histologic studies.", "content": "A technique for isolating the enamel organ of the rat incisor for histologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209421"} {"pmid": "4209422", "title": "Experimental study on fractures of the mandibular condylar process (mandibular condylar process fractures).", "content": "Experimental study on fractures of the mandibular condylar process (mandibular condylar process fractures).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209422"} {"pmid": "4209423", "title": "Closed condylotomy in the treatment of osteoarthritis of the temporomandibular joint.", "content": "Closed condylotomy in the treatment of osteoarthritis of the temporomandibular joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209423"} {"pmid": "4209424", "title": "A histologic study of experimentally induced periapical inflammation in primary teeth in monkeys.", "content": "A histologic study of experimentally induced periapical inflammation in primary teeth in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209424"} {"pmid": "4209425", "title": "Treatment of oroantral communication.", "content": "Treatment of oroantral communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209425"} {"pmid": "4209426", "title": "Absorbable synthetic suture material for internal fixation of fractures of the mandible.", "content": "Absorbable synthetic suture material for internal fixation of fractures of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209426"} {"pmid": "4209427", "title": "Aspiration cytology in the diagnosis of orofacial masses.", "content": "Aspiration cytology in the diagnosis of orofacial masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209427"} {"pmid": "4209430", "title": "An improved high-level whole-body counter.", "content": "An improved high-level whole-body counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209430"} {"pmid": "4209429", "title": "Cellular necrosis model in tissue culture: uptake of 99mTc-tetracycline and the pertechnetate ion.", "content": "Cellular necrosis model in tissue culture: uptake of 99mTc-tetracycline and the pertechnetate ion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209429"} {"pmid": "4209431", "title": "Iron hydroxide particle retention in primate lungs.", "content": "Iron hydroxide particle retention in primate lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209431"} {"pmid": "4209434", "title": "Orosomucoid content of pleural and peritoneal effusions.", "content": "Orosomucoid content of pleural and peritoneal effusions. 22 nonneoplastic, noninflammatory effusions (cirrhosis and congestive heart failure), 12 non-neoplastic inflammatory effusions (tuberculosis, lupus erythematosus, rheumatoid arthritis, and idiopathic pleuropericarditis), and 58 neoplastic effusions (cancer of lung, breast, ovary, and pancreas, and lymphoma) were analyzed by radial immunodiffusion for orosomucoid concentration. The average concentration +/-SE was 35+/-4, 65+/-17, and 130+/-13 mg/100 ml in the three types of effusion, respectively. By gel filtration and ion exchange chromatography, orosomucoid was isolated from 12 nonmalignant and 14 malignant fluids. The orosomucoid preparations reacted as single components in acrylamide gel electrophoresis at pH 9.0, and in immunodiffusion and immunoelectrophoresis against antisera to human serum and to human plasma orosomucoid. In radial immunodiffusion, the slope of the line relating concentration to the square of the diameter of the precipitate area was identical for orosomucoid isolated from normal human plasma and from nonneoplastic effusions, but was subnormal for orosomucoid isolated from neoplastic fluids. All orosomucoid preparations had normal amino acid composition. Orosomucoid from the nonmalignant effusions had normal carbohydrate content. 11 of 14 samples of orosomucoid isolated from neoplastic fluids had abnormalities in carbohydrate composition, consisting of subnormal content of sialic acid (11 of 14), hexose (10 of 14), and hexosamine (3 of 14), and abnormally high content of hexosamine (4 of 14). Discriminant analysis showed that concentration of orosomucoid distinguished between neoplastic and nonneoplastic noninflammatory effusions more effectively than concentration of total protein, albumin, alpha(1), alpha(2), beta, or gamma-globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209434"} {"pmid": "4209436", "title": "Multiple complications and death following protriptyline overdose.", "content": "Multiple complications and death following protriptyline overdose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209436"} {"pmid": "4209435", "title": "Clorazepate dipotassium in the treatment of intractable epilepsy.", "content": "Clorazepate dipotassium in the treatment of intractable epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209435"} {"pmid": "4209437", "title": "Autotransfusion in the subhuman primate.", "content": "Autotransfusion in the subhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209437"} {"pmid": "4209438", "title": "Surgical management of perforated duodenal diverticula.", "content": "Surgical management of perforated duodenal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209438"} {"pmid": "4209439", "title": "Nonoperative roentgenologic instrumentation technics of the postoperative biliary tract. Treatment of biliary stricture and retained stones.", "content": "Nonoperative roentgenologic instrumentation technics of the postoperative biliary tract. Treatment of biliary stricture and retained stones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209439"} {"pmid": "4209440", "title": "Nitrogen and amino acid metabolism in adults with protein-calorie malnutrition.", "content": "Nitrogen and amino acid metabolism in adults with protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209440"} {"pmid": "4209450", "title": "[Repeat intervention of the biliary tract from the internistic viewpoint].", "content": "[Repeat intervention of the biliary tract from the internistic viewpoint].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209450"} {"pmid": "4209453", "title": "An electron microscopic study of the intracellular development of echovirus 22.", "content": "An electron microscopic study of the intracellular development of echovirus 22.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209453"} {"pmid": "4209454", "title": "Studies on the mechanisms of influenza virus infection in hamster trachea organ culture. Correlation of reduced viral adsorption with age-related resistance to infection.", "content": "Studies on the mechanisms of influenza virus infection in hamster trachea organ culture. Correlation of reduced viral adsorption with age-related resistance to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209454"} {"pmid": "4209455", "title": "Comparison of maternal and cord serum titres for measles and for rubella antibodies.", "content": "Comparison of maternal and cord serum titres for measles and for rubella antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209455"} {"pmid": "4209456", "title": "Bovine respiratory syncytial virus: host range in laboratory animals and cell cultures.", "content": "Bovine respiratory syncytial virus: host range in laboratory animals and cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209456"} {"pmid": "4209457", "title": "Enzymic properties of diamine oxidase from hog kidney.", "content": "Enzymic properties of diamine oxidase from hog kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209457"} {"pmid": "4209460", "title": "Impairments in primate information processing resulting from nitrogen narcosis.", "content": "Impairments in primate information processing resulting from nitrogen narcosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209460"} {"pmid": "4209461", "title": "Hippocampal, hypothalamic and lateral geniculate activity during visual discrimination in the monkey.", "content": "Hippocampal, hypothalamic and lateral geniculate activity during visual discrimination in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209461"} {"pmid": "4209462", "title": "Cell mediated lympholysis in man. A case of \"non relevant\" killing of third party persons.", "content": "Cell mediated lympholysis in man. A case of \"non relevant\" killing of third party persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209462"} {"pmid": "4209465", "title": "Carbonic anhydrase activity in the saliva of children and its relation to caries activity.", "content": "Carbonic anhydrase activity in the saliva of children and its relation to caries activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209465"} {"pmid": "4209469", "title": "Nasal congestion as a side effect of cromolyn sodium.", "content": "Nasal congestion as a side effect of cromolyn sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209469"} {"pmid": "4209470", "title": "Thyrotropin-releasing hormone in chicks.", "content": "Thyrotropin-releasing hormone in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209470"} {"pmid": "4209471", "title": "Letter: Replacement treatment of hypothyroidism.", "content": "Letter: Replacement treatment of hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209471"} {"pmid": "4209472", "title": "Stabilization and activation of a human glucose-6-phosphate dehydrogenase variant with enzyme deficiency by specific antibody.", "content": "Stabilization and activation of a human glucose-6-phosphate dehydrogenase variant with enzyme deficiency by specific antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209472"} {"pmid": "4209473", "title": "[The antibacterial activity of thyme and wild thyme oils].", "content": "[The antibacterial activity of thyme and wild thyme oils].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209473"} {"pmid": "4209474", "title": "Iodometric determination of penicillins using iodine monochloride.", "content": "Iodometric determination of penicillins using iodine monochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209474"} {"pmid": "4209475", "title": "Fine structure of Haemoproteus columbae Kruse during macrogametogenesis and fertilization.", "content": "Fine structure of Haemoproteus columbae Kruse during macrogametogenesis and fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209475"} {"pmid": "4209476", "title": "Intestinal parasite survey of kindergarten children in New Orleans.", "content": "Intestinal parasite survey of kindergarten children in New Orleans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209476"} {"pmid": "4209478", "title": "Recent advances in the pathophysiology of the parathyroid glands.", "content": "Recent advances in the pathophysiology of the parathyroid glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209478"} {"pmid": "4209482", "title": "Chemotaxis toward amino acids in Bacillus subtilis.", "content": "Chemotaxis toward amino acids in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209482"} {"pmid": "4209483", "title": "Conjugation and phage MS 2 infection with Hfr Escherichia coli.", "content": "Conjugation and phage MS 2 infection with Hfr Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209483"} {"pmid": "4209484", "title": "Molecular heterogeneity of the bdellovibrios: metallo and serine proteases unique to each species.", "content": "Molecular heterogeneity of the bdellovibrios: metallo and serine proteases unique to each species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209484"} {"pmid": "4209485", "title": "Autolytic activity associated with myxospore formation in Myxococcus xanthus.", "content": "Autolytic activity associated with myxospore formation in Myxococcus xanthus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209485"} {"pmid": "4209487", "title": "Algicidal effect of 2,4-dichlorophenoxy acetic acid on blue-green alga Cylindrospermum sp.", "content": "Algicidal effect of 2,4-dichlorophenoxy acetic acid on blue-green alga Cylindrospermum sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209487"} {"pmid": "4209486", "title": "Selective inhibition of plasmid DNA production in Bacillus megaterium by 6-(p-hydroxy-phenylazo)-uracil: evidence for multiple maintenance systems.", "content": "Selective inhibition of plasmid DNA production in Bacillus megaterium by 6-(p-hydroxy-phenylazo)-uracil: evidence for multiple maintenance systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209486"} {"pmid": "4209489", "title": "Proceedings: Effects of PCB administration on two generations and its chronic toxicity on the third generation in mice. 2.", "content": "Proceedings: Effects of PCB administration on two generations and its chronic toxicity on the third generation in mice. 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209489"} {"pmid": "4209490", "title": "Proceedings: Mechanism of action of circulatory drugs with regard to effects on venous return. 2.", "content": "Proceedings: Mechanism of action of circulatory drugs with regard to effects on venous return. 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209490"} {"pmid": "4209492", "title": "Prevention of tuberculous cavity formation by desensitization with tuberculin-active peptide.", "content": "Prevention of tuberculous cavity formation by desensitization with tuberculin-active peptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209492"} {"pmid": "4209493", "title": "Hypersensitivity lung disease in the turkey raising industry.", "content": "Hypersensitivity lung disease in the turkey raising industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209493"} {"pmid": "4209494", "title": "Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins.", "content": "Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209494"} {"pmid": "4209495", "title": "Ontogeny of Tamm-Horsfall urinary glycoprotein.", "content": "Ontogeny of Tamm-Horsfall urinary glycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209495"} {"pmid": "4209497", "title": "Serum proteins and alkaline phosphatase levels in patients with tuberous sclerosis.", "content": "Serum proteins and alkaline phosphatase levels in patients with tuberous sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209497"} {"pmid": "4209498", "title": "A calorimetric study of the binding of sulfonamides and cyanate to carbonic anhydrase.", "content": "A calorimetric study of the binding of sulfonamides and cyanate to carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209498"} {"pmid": "4209499", "title": "Hemoglobin S-Ga Georgia disease: a case report.", "content": "Hemoglobin S-Ga Georgia disease: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209499"} {"pmid": "4209501", "title": "Letter: Intrathoracic foregut cysts.", "content": "Letter: Intrathoracic foregut cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209501"} {"pmid": "4209500", "title": "Sodium valproate in treatment of epilepsy.", "content": "Sodium valproate in treatment of epilepsy. Sodium valproate has a simple chemical structure unlike other anticonvulsants. It has been given to 63 patients with various types of epilepsy whose attacks were frequent and of whom 40 had failed to respond to other anticonvulsants. Fits stopped completely in 27 patients (43%) and 14 (22%) showed a reduction of attacks by more than 50%. The best results were in patients with absences (typical and atypical) associated with spike and wave discharges on the electroencephalogram. Myoclonic epilepsies responded well and improvement occurred with tonic-clonic seizures and focal motor fits. There was little or no improvement in temporal lobe epilepsy. Sodium valproate given alone did not cause unwanted effects but it potentiated many other anticonvulsants. An unusual side effect was temporary hair loss. A number of patients became more alert, school performances improved, and the management of subnormal patients became easier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209500"} {"pmid": "4209502", "title": "Influence of local hydrophobic environment on acid dissociation constants of coordinated water molecules.", "content": "Influence of local hydrophobic environment on acid dissociation constants of coordinated water molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209502"} {"pmid": "4209503", "title": "Immune damage to liposomes containing lipids from Schistosoma mansoni worms.", "content": "Immune damage to liposomes containing lipids from Schistosoma mansoni worms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209503"} {"pmid": "4209505", "title": "Measurement of posture in japanese monkey (Macaca fuscata) by telemetry.", "content": "Measurement of posture in japanese monkey (Macaca fuscata) by telemetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209505"} {"pmid": "4209504", "title": "Mutagenicity testing of cyclamate and some pesticides in Drosophila melanogaster.", "content": "Mutagenicity testing of cyclamate and some pesticides in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209504"} {"pmid": "4209506", "title": "Comparative characterization of microbiological and biological assays of protein quality of some foodstuffs.", "content": "Comparative characterization of microbiological and biological assays of protein quality of some foodstuffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209506"} {"pmid": "4209508", "title": "Amylase content of mixed saliva in children.", "content": "Amylase content of mixed saliva in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209508"} {"pmid": "4209507", "title": "Malignant external otitis and facial paralysis.", "content": "Malignant external otitis and facial paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209507"} {"pmid": "4209510", "title": "Serum IgE levels in individuals infected with Schistosoma mansoni and Schistosoma haematobium.", "content": "Serum IgE levels in individuals infected with Schistosoma mansoni and Schistosoma haematobium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209510"} {"pmid": "4209509", "title": "Animal atmospheric exposure chamber system using a modified tank respirator.", "content": "Animal atmospheric exposure chamber system using a modified tank respirator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209509"} {"pmid": "4209511", "title": "Gonorrhea.", "content": "Gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209511"} {"pmid": "4209512", "title": "The IUD and prostaglandins: a review of the evidence.", "content": "The IUD and prostaglandins: a review of the evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209512"} {"pmid": "4209513", "title": "Microbial production of cobalamin (vitamin B 12).", "content": "Microbial production of cobalamin (vitamin B 12).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209513"} {"pmid": "4209515", "title": "Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria.", "content": "Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. Various species of Streptomyces possess aminoglycoside-modifying enzymes. Streptomyces kanamyceticus contains an enzyme that acetylates the 6'-amino group of kanamycin A and B, gentamicin C(1a), and neomycin. Streptomyces spectabilis produces an enzyme that acetylates the 2'-amino group of the hexose ring of gentamicin C(1a). These enzymes catalyze reactions identical to those catalyzed by enzymes found in gram-negative bacteria containing R(antibiotic resistance)-factors. The discovery of these enzymes suggests the possibility of an evolutionary relationship between the aminoglycosideinactivating enzymes (produced by resistance determinants) in bacteria containing R-factors and similar enzymes found in the actinomycetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209515"} {"pmid": "4209516", "title": "Methyldopa: physicochemical characterization of the erythrocyte autoantibody.", "content": "Methyldopa: physicochemical characterization of the erythrocyte autoantibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209516"} {"pmid": "4209517", "title": "The etiology and implications of lactose intolerance.", "content": "The etiology and implications of lactose intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209517"} {"pmid": "4209518", "title": "An inhibitory effect of tolbutamide and glibenclamide (glyburide) on the pancreatic islets of normal animals.", "content": "An inhibitory effect of tolbutamide and glibenclamide (glyburide) on the pancreatic islets of normal animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209518"} {"pmid": "4209521", "title": "Galvanic skin responses (GSR) and plethysmographic changes induced by chlorimipramine, imipramine and placebo.", "content": "Galvanic skin responses (GSR) and plethysmographic changes induced by chlorimipramine, imipramine and placebo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209521"} {"pmid": "4209520", "title": "Physical compatibility and chemical stability of cephapirin sodium in combination with non-antibiotic drugs in large-volume parenteral solutions. II.", "content": "Physical compatibility and chemical stability of cephapirin sodium in combination with non-antibiotic drugs in large-volume parenteral solutions. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209520"} {"pmid": "4209523", "title": "The ultrastructure of the rat renal medulla as observed after improved fixation methods.", "content": "The ultrastructure of the rat renal medulla as observed after improved fixation methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209523"} {"pmid": "4209522", "title": "Activity of BB-K8 (amikacin) against clinical isolates resistant to one or more aminoglycoside antibiotics.", "content": "Activity of BB-K8 (amikacin) against clinical isolates resistant to one or more aminoglycoside antibiotics. One hundred fifty-two bacterial strains that possess resistance to kanamycin A, gentamicin, or tobramycin, or to more than one of these antibiotics, were collected from various sources in Canada, Europe, Japan, and the United States. This collection was composed of Staphylococcus aureus and Pseudomonas aeruginosa and members of the Enterobacteriaceae family. Their susceptibility to BB-K8 (amikacin), a new broad-spectrum semisynthetic derivative of kanamycin A, and to the other agents, was determined on Mueller-Hinton Medium by the twofold agar dilution method. Test results revealed that 60.5% of the isolates were resistant to 8 mug of tobramycin per ml, 67.1% to 8 mug of gentamicin per ml, 86.2% to 20 mug of kanamycin A per ml, and only 8.6% to 20 mug of amikacin per ml. Of interest is the fact that the amikacin-resistant strains were generally resistant to all of the other aminoglycosides. The broad spectrum of amikacin was not totally unexpected, because the compound has been shown to be a poor substrate for most enzymes that inactivate other aminoglycosides through O-phosphorylation, O-adenylylation, or N-acetylation. A number of susceptibility profiles were obtained when the organisms were tested against a series of nine aminoglycosides. The majority of these profiles resembled those found for organisms that possess known mechanisms of enzymatic inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209522"} {"pmid": "4209524", "title": "Editorial: Familial medullary carcinoma of the thyroid.", "content": "Editorial: Familial medullary carcinoma of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209524"} {"pmid": "4209525", "title": "Biliary magnesium loss in the postoperative patient.", "content": "Biliary magnesium loss in the postoperative patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209525"} {"pmid": "4209528", "title": "Cell death and autonomous gene action in lethals affecting imaginal discs in Drosophila melanogaster.", "content": "Cell death and autonomous gene action in lethals affecting imaginal discs in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209528"} {"pmid": "4209529", "title": "Biological properties of macarbomycin, an antibiotic containing phosphorus.", "content": "Biological properties of macarbomycin, an antibiotic containing phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209529"} {"pmid": "4209530", "title": "Letter: Four minor antibiotics from macarbomycins.", "content": "Letter: Four minor antibiotics from macarbomycins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209530"} {"pmid": "4209531", "title": "EM49, a new peptide antibiotic. I. Fermentation, isolation, and preliminary characterization.", "content": "EM49, a new peptide antibiotic. I. Fermentation, isolation, and preliminary characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209531"} {"pmid": "4209533", "title": "Letter: Synthesis of (S)-4-amino-2-hydroxybutyryl derivatives of 3',4'-dideoxykanamycin B and their antibacterial activities.", "content": "Letter: Synthesis of (S)-4-amino-2-hydroxybutyryl derivatives of 3',4'-dideoxykanamycin B and their antibacterial activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209533"} {"pmid": "4209535", "title": "Sarcoidal reactions in animals intensively immunized with tetanus vaccine.", "content": "Sarcoidal reactions in animals intensively immunized with tetanus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209535"} {"pmid": "4209534", "title": "Two types of melanogenesis in monolayer cultures of melanoma cells.", "content": "Two types of melanogenesis in monolayer cultures of melanoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209534"} {"pmid": "4209536", "title": "Effects of 2,4-dinitrophenol and dinactin on heat-sensitive and ecdysone-specific puffs of Drosophila salivary gland chromosomes in vitro.", "content": "Effects of 2,4-dinitrophenol and dinactin on heat-sensitive and ecdysone-specific puffs of Drosophila salivary gland chromosomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209536"} {"pmid": "4209538", "title": "Antigenic differences between normal mouse epidermis and methylcholanthrene-induced squamous-cell carcinomas.", "content": "Antigenic differences between normal mouse epidermis and methylcholanthrene-induced squamous-cell carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209538"} {"pmid": "4209543", "title": "Long-term management of airway secretions and bronchospasm in chronic obstructive lung disease.", "content": "Long-term management of airway secretions and bronchospasm in chronic obstructive lung disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209543"} {"pmid": "4209544", "title": "Transient peripheral plasmacytosis.", "content": "Transient peripheral plasmacytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209544"} {"pmid": "4209547", "title": "Isolation and in vitro cultivation of the mammalian microsporidian Encephalitozoon cuniculi.", "content": "Isolation and in vitro cultivation of the mammalian microsporidian Encephalitozoon cuniculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209547"} {"pmid": "4209545", "title": "Early appearance and regional differences in intraneuronal and extraneuronal lipofuscin accumulation with age in the brain of a nonhuman primate (Macaca mulatta).", "content": "Early appearance and regional differences in intraneuronal and extraneuronal lipofuscin accumulation with age in the brain of a nonhuman primate (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209545"} {"pmid": "4209546", "title": "Bone mineral content of the femoral neck after irradiation.", "content": "Bone mineral content of the femoral neck after irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209546"} {"pmid": "4209548", "title": "Evaluation of bladder diverticulum using fiberoptic bronchoscope.", "content": "Evaluation of bladder diverticulum using fiberoptic bronchoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209548"} {"pmid": "4209550", "title": "Problems in the extraction DNA when utilizing pancreatic RNAase and pronase.", "content": "Problems in the extraction DNA when utilizing pancreatic RNAase and pronase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209550"} {"pmid": "4209549", "title": "Properties and function of the pyruvate: ferredoxin oxidoreductase from the blue-green alga Anabaena cylindrica.", "content": "Properties and function of the pyruvate: ferredoxin oxidoreductase from the blue-green alga Anabaena cylindrica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209549"} {"pmid": "4209554", "title": "The effects of protein synthesis-inhibiting antibiotics on the puffing pattern of Drosophila salivary gland chromosomes in vitro.", "content": "The effects of protein synthesis-inhibiting antibiotics on the puffing pattern of Drosophila salivary gland chromosomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209554"} {"pmid": "4209555", "title": "Population mean marrow dose and leukaemia significant dose from beam-therapy in Japan, 1971.", "content": "Population mean marrow dose and leukaemia significant dose from beam-therapy in Japan, 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209555"} {"pmid": "4209556", "title": "The anatomical basis of prosopagnosia.", "content": "The anatomical basis of prosopagnosia. Evidence is presented that patients with prosopagnosia have right anterior inferior occipital lesions in the region of the occipital temporal junction. Many if not all cases have an additional lesion in the left hemisphere; this is often but apparently not always symmetrical with the right hemisphere lesion. This evidence is discussed in relation to the anatomical connections of these regions and the results of experiments in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209556"} {"pmid": "4209557", "title": "Isozymes of lysozyme in leukocytes and egg white: evidence for the species-specific control of egg-white lysozyme synthesis.", "content": "Isozymes of lysozyme in leukocytes and egg white: evidence for the species-specific control of egg-white lysozyme synthesis. Two structurally distinct forms of eggwhite lysozyme (EC 3.2.1.17) are known. The egg white of some species contains both of these forms, while the egg white of other species appears to contain only one or the other of them. We have immunological and electrophoretic evidence that the chicken, which has only one lysozyme type in its egg white, contains both types in its polymorphonuclear leukocytes. Experiments on Embden goose bone marrow showed that this tissue also contains both lysozymes, even though the egg white of this species contains only one of them. Our studies suggest that many avian species have the genetic loci that code for both forms of lysozyme, but that a species-specific regulatory mechanism controls whether one or the other or both of them are expressed during egg white production. The fact that two distinct lysozymes are present in chicken leukocytes may be of significance to the antibacterial mechanism of these cells, especially in light of the fact that they lack myeloperoxidase, an important leukocyte enzyme in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209557"} {"pmid": "4209558", "title": "The activity-related ionization in carbonic anhydrase.", "content": "The activity-related ionization in carbonic anhydrase. The catalytic activity of carbonic anhydrase (EC 4.2.1.1) is linked to the ionization of a group in close proximity to the essential zinc ion. Studies have been undertaken to delineate the ionizations germane to the active-site chelate system. Several imidazole ligand systems were studied in order to approach a representative chelate. The simplest involved the complexation of Zn(II) by imidazole and by N-methylimidazole. As well, two bidentate systems, Zn(II)-4,4'-bis-imidazoylmethane and Co(II)-cyclic-L-histidyl-L-histidine were investigated. It was found that in a species containing metal-bound water and imidazole coordinated by means of the pyridinium nitrogen, the most acidic group was the pyrrole N-H in the imidazole ring. By the use of N-methylimidazole, the pK(a) of a metal-bound water molecule in a tri-imidazole ligand field was found to be 9.1. Noting the preference for labilization of the pyrrole hydrogen, the catalytic features of carbonic anhydrase are reexamined assuming that the pK(enz) is associated with the N-H ionization, and not with the ionization of metal-bound water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209558"} {"pmid": "4209563", "title": "Viral infections of the fetus.", "content": "Viral infections of the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209563"} {"pmid": "4209567", "title": "Serum and cerebrospinal fluid magnesium and calcium contents in idiopathic grandmal epilepsy.", "content": "Serum and cerebrospinal fluid magnesium and calcium contents in idiopathic grandmal epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209567"} {"pmid": "4209566", "title": "An introduction to principles of veterinary clinical pharmacology: the elimination of drugs. 1. Rate of drug elimination.", "content": "An introduction to principles of veterinary clinical pharmacology: the elimination of drugs. 1. Rate of drug elimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209566"} {"pmid": "4209571", "title": "Manifestations of copper deficiency in a patient with systemic sclerosis on intravenous hyperalimentation.", "content": "Manifestations of copper deficiency in a patient with systemic sclerosis on intravenous hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209571"} {"pmid": "4209572", "title": "Blood viscosity in Waldenström's macroglobulinemia.", "content": "Blood viscosity in Waldenström's macroglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209572"} {"pmid": "4209573", "title": "Biochemical and genetic studies in two families with Fabry disease.", "content": "Biochemical and genetic studies in two families with Fabry disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209573"} {"pmid": "4209574", "title": "Scanning electron microscopy in the ultrastructural analysis of the mammalian cerebral ventricular system.", "content": "Scanning electron microscopy in the ultrastructural analysis of the mammalian cerebral ventricular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209574"} {"pmid": "4209575", "title": "Renal tubular antigen excretion in normal human urine. I. Immunochemical indentification.", "content": "Renal tubular antigen excretion in normal human urine. I. Immunochemical indentification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209575"} {"pmid": "4209580", "title": "New attachment after treatment of intrabony defects in monkeys.", "content": "New attachment after treatment of intrabony defects in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209580"} {"pmid": "4209578", "title": "Selective release of content from microsomal vesicles without membrane disassembly. II. Electrophoretic and immunological characterization of microsomal subfractions.", "content": "Selective release of content from microsomal vesicles without membrane disassembly. II. Electrophoretic and immunological characterization of microsomal subfractions. Rough and smooth microsomes were shown to have similar sets of polypeptide chains except for the proteins of ribosomes bound to the rough endoplasmic reticulum (ER). More than 50 species of polypeptides were detected by acrylamide gel electrophoresis, ranging in molecular weight from 10,000 to approximately 200,000 daltons. The content of rough and smooth microsomes was separated from the membrane vesicles using sublytic concentrations of detergents and differential centrifugation. A specific subset of proteins which consisted of approximately 25 polypeptides was characteristic of the microsomal content. Some of these proteins showed high rates of in vivo incorporation of radioactive leucine or glucosamine, but several others incorporated only low levels of radioactivity within short labeling intervals and appeared to be long-term residents of the lumen of the ER. Seven polypeptides in the content subfractions, including serum albumin, contained almost 50% of the leucine radioactivity incorporated during 5 min and cross-reacted with antiserum against rat serum. Almost all microsomal glycoproteins were at least partly released with the microsomal content. Smooth microsomes contained higher levels of albumin than rough microsomes, but after short times of labeling with [(3)H]leucine the specific activity of albumin in the latter was higher, supporting the notion that newly synthesized serum proteins are transferred from rough to smooth portions of the ER. On the other hand, after labeling for 30 min with [(3)H]glucosamine, smooth microsomes contained higher levels of radioactivity than rough microsomes. This would be expected if glycosidation of newly synthesized polypeptides proceeds during their transit through ER cisternae. The labeling pattern of membrane proteins in microsomes obtained from animals which received three daily injections of [(3)H]leucine, the last administered 1 day before sacrifice, followed the intensity of bands stained with Coomassie blue, with a main radioactive peak corresponding to cytochrome P 450. After the long-term labeling procedure most content proteins had low levels of radioactivity; this was especially true of serum proteins which were highly labeled after 30 min.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209578"} {"pmid": "4209579", "title": "Antibody-mediated effects on the periodontium.", "content": "Antibody-mediated effects on the periodontium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209579"} {"pmid": "4209577", "title": "Reversible, thermotropic alteration of nuclear membrane stucture and nucleocytoplasmic RNA transport in Tetrahymena.", "content": "Reversible, thermotropic alteration of nuclear membrane stucture and nucleocytoplasmic RNA transport in Tetrahymena. We examine the effect of cooling upon the freeze-etch ultrastructure of nuclear membranes, as well as upon nucleocytoplasmic RNA transport in the unicellular eukaryote Tetrahymena pyriformis. Chilling produces smooth, particle-free areas on both faces of the two freeze-fractured macronuclear membranes. Upon return to optimum growth temperature the membrane-associated particles revert to their normal uniform distribution and the smooth areas disappear. Chilling lowers the incorporation of [(14)C]uridine into whole cells and their cytoplasmic RNA. Cooling from the optimum growth temperature of 28 degrees to 18 degrees C (or above) decreases [(14)C]uridine incorporation into cells more than into their cytoplasmic RNA; chilling to below 18 degrees C but above 10 degrees C causes the reverse. [(14)C]Uridine incorporation into whole cells and their cytoplasmic RNA reflects overall RNA synthesis and nucleocytoplasmic RNA transport, respectively. RNA transport decreases strongly between 20 degrees and 16 degrees C, which is also the temperature range where morphologically detectable nuclear membrane transitions occur. This suggests that the nuclear envelope limits the rate of nucleocytoplasmic RNA transport at low temperatures. We hypothesize that a thermotropic lipid phase transition switches nuclear pore complexes from an \"open\" to a \"closed\" state with respect to nucleocytoplasmic RNA transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209577"} {"pmid": "4209581", "title": "Osseous grafts and implants in the restoration of large oral defects.", "content": "Osseous grafts and implants in the restoration of large oral defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209581"} {"pmid": "4209583", "title": "In vitro and in vivo activity of certain thiosemicarbazones against Trypanosoma cruzi.", "content": "In vitro and in vivo activity of certain thiosemicarbazones against Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209583"} {"pmid": "4209582", "title": "Amine functions of reduced basicity. Hypoglycemic and natriuretic alpha-alkoxybenzylamidoximes, amidines, and cycloamidines.", "content": "Amine functions of reduced basicity. Hypoglycemic and natriuretic alpha-alkoxybenzylamidoximes, amidines, and cycloamidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209582"} {"pmid": "4209584", "title": "Comparison of culture-induced, phenobarbital-induced and naturally-developing UDP-glucuronyltransferase.", "content": "Comparison of culture-induced, phenobarbital-induced and naturally-developing UDP-glucuronyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209584"} {"pmid": "4209585", "title": "Nature of residual erythrocyte catalase activity in Swiss-type acatalasemia.", "content": "Nature of residual erythrocyte catalase activity in Swiss-type acatalasemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209585"} {"pmid": "4209587", "title": "Migration of mast cells through the area postrema.", "content": "Migration of mast cells through the area postrema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209587"} {"pmid": "4209588", "title": "A rapid technique for separation of thymocytes from suspensions by centrifugation through silicone oil.", "content": "A rapid technique for separation of thymocytes from suspensions by centrifugation through silicone oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209588"} {"pmid": "4209589", "title": "Electron microscopic autoradiographic study of cholesteral passage across arterial and capillary endothelium.", "content": "Electron microscopic autoradiographic study of cholesteral passage across arterial and capillary endothelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209589"} {"pmid": "4209590", "title": "Transfer of heme from ferrihemoglobin and ferrihemoglobin isolated chains to hemopexin.", "content": "Transfer of heme from ferrihemoglobin and ferrihemoglobin isolated chains to hemopexin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209590"} {"pmid": "4209591", "title": "A woman with multiple congenital anomalies, mental retardation and mosaicism for an unusual translocation chromosome t(6;19).", "content": "A woman with multiple congenital anomalies, mental retardation and mosaicism for an unusual translocation chromosome t(6;19).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209591"} {"pmid": "4209592", "title": "Partial trisomy 13 in a case of Cyclopia with 13-14 translocation.", "content": "Partial trisomy 13 in a case of Cyclopia with 13-14 translocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209592"} {"pmid": "4209595", "title": "Factors involved in the production of amblyopia.", "content": "Factors involved in the production of amblyopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209595"} {"pmid": "4209596", "title": "Ruptured cervical aneurysm with neurofibromatosis.", "content": "Ruptured cervical aneurysm with neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209596"} {"pmid": "4209599", "title": "Cutis verticis gyrata and the Lennox syndrome.", "content": "Cutis verticis gyrata and the Lennox syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209599"} {"pmid": "4209600", "title": "Cerebral degenerative disorders of infancy and childhood.", "content": "Cerebral degenerative disorders of infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209600"} {"pmid": "4209601", "title": "Endogenous glyceride synthesis rate in baboons fed diets containing sucrose or glucose.", "content": "Endogenous glyceride synthesis rate in baboons fed diets containing sucrose or glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209601"} {"pmid": "4209602", "title": "Lymphoma in owl monkeys (Aotus trivirgatus) inoculated with Herpesvirus saimiri: clinical, hematologic and pathologic findings.", "content": "Lymphoma in owl monkeys (Aotus trivirgatus) inoculated with Herpesvirus saimiri: clinical, hematologic and pathologic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209602"} {"pmid": "4209603", "title": "Recognition impaired and association intact in the memory of monkeys after transection of the fornix.", "content": "Recognition impaired and association intact in the memory of monkeys after transection of the fornix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209603"} {"pmid": "4209604", "title": "A non-modality specific impairment in spatial learning after fornix lesions in monkeys.", "content": "A non-modality specific impairment in spatial learning after fornix lesions in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209604"} {"pmid": "4209605", "title": "Specialization of the left hemisphere in baboon-evidence from directional preferences.", "content": "Specialization of the left hemisphere in baboon-evidence from directional preferences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209605"} {"pmid": "4209597", "title": "Segmental middle cerebral artery occlusion in primates: an experimental method requiring minimal surgery and anesthesia.", "content": "Segmental middle cerebral artery occlusion in primates: an experimental method requiring minimal surgery and anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209597"} {"pmid": "4209598", "title": "The distribution and density of reduced cerebral blood flow following acute middle cerebral artery occlusion: an experimental study by the technique of hydrogen clearance in baboons.", "content": "The distribution and density of reduced cerebral blood flow following acute middle cerebral artery occlusion: an experimental study by the technique of hydrogen clearance in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209598"} {"pmid": "4209619", "title": "The amino acid sequence of streptomyces griseus trypsin. II; The tryptic peptides.", "content": "The amino acid sequence of streptomyces griseus trypsin. II; The tryptic peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209619"} {"pmid": "4209621", "title": "Animal DNA-dependent RNA polymerases. Molecular structures and immunological properties of calf-thymus enzyme AI and of calf-thymus and rat-liver enzymes B.", "content": "Animal DNA-dependent RNA polymerases. Molecular structures and immunological properties of calf-thymus enzyme AI and of calf-thymus and rat-liver enzymes B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209621"} {"pmid": "4209622", "title": "An immunological investigation of the structure and function of ribulose 1,5-bisphosphate carboxylase.", "content": "An immunological investigation of the structure and function of ribulose 1,5-bisphosphate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209622"} {"pmid": "4209623", "title": "Isolation of carbonic anhydrase from dog erythrocytes and determination of its N-terminal amino-acid sequence.", "content": "Isolation of carbonic anhydrase from dog erythrocytes and determination of its N-terminal amino-acid sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209623"} {"pmid": "4209625", "title": "Editorial: Diabetes in the young.", "content": "Editorial: Diabetes in the young.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209625"} {"pmid": "4209626", "title": "Recent advances in surgery of the brain. Dr. P. Kutumbiah endowment lecture--1971.", "content": "Recent advances in surgery of the brain. Dr. P. Kutumbiah endowment lecture--1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209626"} {"pmid": "4209627", "title": "Place of the anesthetist in the intensive care unit.", "content": "Place of the anesthetist in the intensive care unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209627"} {"pmid": "4209629", "title": "Coccidia of the cotton rat, Sigmodon hispidus, from Alabama.", "content": "Coccidia of the cotton rat, Sigmodon hispidus, from Alabama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209629"} {"pmid": "4209630", "title": "Mandibular joint involvement in a case of Fanconi's syndrome with renal failure.", "content": "Mandibular joint involvement in a case of Fanconi's syndrome with renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209630"} {"pmid": "4209628", "title": "Use of parenteral hyperalimentation in treatment of alkaline reflux gastritis.", "content": "Use of parenteral hyperalimentation in treatment of alkaline reflux gastritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209628"} {"pmid": "4209631", "title": "Coeliac disease. Barium studies.", "content": "Coeliac disease. Barium studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209631"} {"pmid": "4209634", "title": "Unusual spondyloepiphyseal and spondylometaphyseal dysplasias of childhood.", "content": "Unusual spondyloepiphyseal and spondylometaphyseal dysplasias of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209634"} {"pmid": "4209632", "title": "The blockade of the local generation of prostaglandins explains the analgesic action of aspirin.", "content": "The blockade of the local generation of prostaglandins explains the analgesic action of aspirin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209632"} {"pmid": "4209643", "title": "Effects of puff-adder venom on coagulation, fibrinolysis and platelet aggregation in the baboon.", "content": "Effects of puff-adder venom on coagulation, fibrinolysis and platelet aggregation in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209643"} {"pmid": "4209640", "title": "Transferable resistance to carbenicillin and gentamicin in Pseudomonas aeruginosa.", "content": "Transferable resistance to carbenicillin and gentamicin in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209640"} {"pmid": "4209638", "title": "The clinical usefulness of C-reactive protein (CRP) determinations in bacterial meningitis and septicemia in infancy.", "content": "The clinical usefulness of C-reactive protein (CRP) determinations in bacterial meningitis and septicemia in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209638"} {"pmid": "4209642", "title": "Detection of biological false positive syphilis serum reactions.", "content": "Detection of biological false positive syphilis serum reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209642"} {"pmid": "4209641", "title": "A carbenicillin R factor from Pseudomonas aeruginosa.", "content": "A carbenicillin R factor from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209641"} {"pmid": "4209644", "title": "Combined action of sulbenicillin and gentamicin.", "content": "Combined action of sulbenicillin and gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209644"} {"pmid": "4209646", "title": "Epiphyseal injuries.", "content": "Epiphyseal injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209646"} {"pmid": "4209647", "title": "The child who convulses with fever.", "content": "The child who convulses with fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209647"} {"pmid": "4209645", "title": "Pediatric surgery. Current concepts.", "content": "Pediatric surgery. Current concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209645"} {"pmid": "4209648", "title": "Normal serum triiodothyronine concentration and the lack of TSH response to TRH in patients with euthyroid Graves' disease.", "content": "Normal serum triiodothyronine concentration and the lack of TSH response to TRH in patients with euthyroid Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209648"} {"pmid": "4209651", "title": "Viral and non-viral properties of the scrapie agent.", "content": "Viral and non-viral properties of the scrapie agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209651"} {"pmid": "4209649", "title": "Fluorescein angiography of the glaucomatous disc.", "content": "Fluorescein angiography of the glaucomatous disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209649"} {"pmid": "4209650", "title": "Kuru and Creutzfeldt-Jakob disease. Experimental models of noninflammatory degenerative slow virus disease of the central nervous system.", "content": "Kuru and Creutzfeldt-Jakob disease. Experimental models of noninflammatory degenerative slow virus disease of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209650"} {"pmid": "4209652", "title": "Enhancement of baboon liver allografts with noncytotoxic preparations of alloimmune IgG.", "content": "Enhancement of baboon liver allografts with noncytotoxic preparations of alloimmune IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209652"} {"pmid": "4209653", "title": "Antimacaque thymocyte globulins. Toxicity and immunodepressive effect in the human species.", "content": "Antimacaque thymocyte globulins. Toxicity and immunodepressive effect in the human species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209653"} {"pmid": "4209657", "title": "Genetic transformation of the blue-green bacterium, Anacystis nidulans.", "content": "Genetic transformation of the blue-green bacterium, Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209657"} {"pmid": "4209661", "title": "Food preservation and antibacterial properties of four fluoroalkane compounds.", "content": "Food preservation and antibacterial properties of four fluoroalkane compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209661"} {"pmid": "4209660", "title": "Human antibody response to group A streptococcal teichoic acid.", "content": "Human antibody response to group A streptococcal teichoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209660"} {"pmid": "4209662", "title": "Prolactin and thyrotropin in thyroid diseases: lack of evidence for a physiological role of thyrotropin-releasing hormone in the regulation of prolactin secretion.", "content": "Prolactin and thyrotropin in thyroid diseases: lack of evidence for a physiological role of thyrotropin-releasing hormone in the regulation of prolactin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209662"} {"pmid": "4209663", "title": "Vertebral epidermal transamidases.", "content": "Vertebral epidermal transamidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209663"} {"pmid": "4209664", "title": "Relative rates of transcapillary movement of free thyroxine, protein-bound thyroxine, thyroxine-binding proteins, and albumin.", "content": "Relative rates of transcapillary movement of free thyroxine, protein-bound thyroxine, thyroxine-binding proteins, and albumin. The rate of appearance of labeled thyroxine (T4) and albumin in lymph from various areas after simultaneous i.v. injection of the labeled substances in conscious ambulatory sheep has been used to estimate the relative rates of transcapillary movement of stable T4 and albumin. Labeled T4 appeared in hepatic lymph at the same rate as albumin. In intestinal and leg lymph, labeled T4 appeared eight and four times as rapidly as albumin indicating that T4 crosses capillaries in these areas independently of and much more rapidly than albumin and other proteins having similar distribution kinetics. The lymph:plasma ratios for all the T4-binding proteins including albumin were very similar in any one area showing that the relative fractional rates of transcapillary movement of these proteins were very similar. Therefore in extrahepatic areas, transcapillary movement of T4 in the protein-bound form was quantitatively much less important than in the free form. The findings support earlier views, recently questioned, that free T4 is of considerable physiological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209664"} {"pmid": "4209666", "title": "Poly-DL-alanyl skin isograft rejection by purified anti-poly-DL-alanyl antibodies.", "content": "Poly-DL-alanyl skin isograft rejection by purified anti-poly-DL-alanyl antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209666"} {"pmid": "4209667", "title": "Interaction between an R factor and an element conferring resistance to mercuric ions in Pseudomonas aeruginosa.", "content": "Interaction between an R factor and an element conferring resistance to mercuric ions in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209667"} {"pmid": "4209669", "title": "X-ray induced mitotic recombination in Drosophila melanogaster. 3. Dose dependence of the \"pairing\" component.", "content": "X-ray induced mitotic recombination in Drosophila melanogaster. 3. Dose dependence of the \"pairing\" component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209669"} {"pmid": "4209668", "title": "Direct assay for sigma factor activity and demonstration of the loss of this activity during sporulation in Bacillus subtilis.", "content": "Direct assay for sigma factor activity and demonstration of the loss of this activity during sporulation in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209668"} {"pmid": "4209671", "title": "Phenotypic properties of Bacillus subtilis mutants defective in recombination and repair functions.", "content": "Phenotypic properties of Bacillus subtilis mutants defective in recombination and repair functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209671"} {"pmid": "4209670", "title": "The ribosomal proteins of Drosophila melanogaster. 3. Further studies on the ribosomal protein composition during development.", "content": "The ribosomal proteins of Drosophila melanogaster. 3. Further studies on the ribosomal protein composition during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209670"} {"pmid": "4209678", "title": "Actions of chinoform and oxine on the isolated phrenic nerve-diaphragm preparation of the rat: the accumulation of chinoform by rat diaphragm strip.", "content": "Actions of chinoform and oxine on the isolated phrenic nerve-diaphragm preparation of the rat: the accumulation of chinoform by rat diaphragm strip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209678"} {"pmid": "4209680", "title": "A \"double-blind\" trial of disodium cromoglycate in Thai asthmatic children.", "content": "A \"double-blind\" trial of disodium cromoglycate in Thai asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209680"} {"pmid": "4209681", "title": "Interferon production by simian lymphoblastoid cell lines.", "content": "Interferon production by simian lymphoblastoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209681"} {"pmid": "4209682", "title": "Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates.", "content": "Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209682"} {"pmid": "4209683", "title": "The induction of a fatal desmoplastic mesothelial reaction in rabbits with mouse Ehrlich ascites carcinomata.", "content": "The induction of a fatal desmoplastic mesothelial reaction in rabbits with mouse Ehrlich ascites carcinomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209683"} {"pmid": "4209684", "title": "Induction of autoallergic gastritis in dogs.", "content": "Induction of autoallergic gastritis in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209684"} {"pmid": "4209685", "title": "Clinical and hormonal response to bromocriptin (CB-154) in the galactorrhea syndromes.", "content": "Clinical and hormonal response to bromocriptin (CB-154) in the galactorrhea syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209685"} {"pmid": "4209686", "title": "Growth hormone in adults with protein-calorie malnutrition.", "content": "Growth hormone in adults with protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209686"} {"pmid": "4209687", "title": "Immunochemical quantitation of human transcortin.", "content": "Immunochemical quantitation of human transcortin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209687"} {"pmid": "4209688", "title": "Thyroxine-binding globulin in infant protein-calorie malnutrition.", "content": "Thyroxine-binding globulin in infant protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209688"} {"pmid": "4209689", "title": "Nanophyetus salmincola infections in kippered salmon.", "content": "Nanophyetus salmincola infections in kippered salmon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209689"} {"pmid": "4209690", "title": "Carcinoma of the cervix: establishment of a hyperbaric oxygen trial associated with the use of the cathetron.", "content": "Carcinoma of the cervix: establishment of a hyperbaric oxygen trial associated with the use of the cathetron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209690"} {"pmid": "4209691", "title": "Nitroglycerin to unmask reversible asynergy. Correlation with post coronary bypass ventriculography.", "content": "Nitroglycerin to unmask reversible asynergy. Correlation with post coronary bypass ventriculography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209691"} {"pmid": "4209692", "title": "The development of the macronucleus in the ciliated protozoan Stylonychia mytilus.", "content": "The development of the macronucleus in the ciliated protozoan Stylonychia mytilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209692"} {"pmid": "4209694", "title": "Computerized intravenous glybenclamide test in early diagnosis of diabetes mellitus.", "content": "Computerized intravenous glybenclamide test in early diagnosis of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209694"} {"pmid": "4209693", "title": "In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas.", "content": "In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209693"} {"pmid": "4209695", "title": "Letter: Development of gelatin-urease films.", "content": "Letter: Development of gelatin-urease films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209695"} {"pmid": "4209696", "title": "Simplified water-loading test in bacteriuria.", "content": "Simplified water-loading test in bacteriuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209696"} {"pmid": "4209701", "title": "Response of units in striate cortex of squirrel monkeys to visual and electrical stimuli.", "content": "Response of units in striate cortex of squirrel monkeys to visual and electrical stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209701"} {"pmid": "4209702", "title": "Effects of dentate cooling on rapid alternating arm movements.", "content": "Effects of dentate cooling on rapid alternating arm movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209702"} {"pmid": "4209704", "title": "Cross-reactivity of monkey pituitary extracts in human radioimmunoassays.", "content": "Cross-reactivity of monkey pituitary extracts in human radioimmunoassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209704"} {"pmid": "4209705", "title": "Effect of exogenous estradiol-17 beta on vitellogenic oocyte growth in ovaries of the toad Bufo bufo bufo (L.) during the postspawning period.", "content": "Effect of exogenous estradiol-17 beta on vitellogenic oocyte growth in ovaries of the toad Bufo bufo bufo (L.) during the postspawning period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209705"} {"pmid": "4209706", "title": "Variations in plasma amino acid concentrations after abdominal surgical procedures.", "content": "Variations in plasma amino acid concentrations after abdominal surgical procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209706"} {"pmid": "4209707", "title": "Investigations on some physico-chemical and immunological properties of viral hepatitis antigen (HB Ag).", "content": "Investigations on some physico-chemical and immunological properties of viral hepatitis antigen (HB Ag).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209707"} {"pmid": "4209708", "title": "Brain growth in children with marasmus. A study using head circumference measurement, transillumination and ultrasonic echo ventriculography.", "content": "Brain growth in children with marasmus. A study using head circumference measurement, transillumination and ultrasonic echo ventriculography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209708"} {"pmid": "4209709", "title": "Intra-abdominal vascular complications of diabetic ketosis.", "content": "Intra-abdominal vascular complications of diabetic ketosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209709"} {"pmid": "4209710", "title": "Carcino--embryonic antigen and its significance.", "content": "Carcino--embryonic antigen and its significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209710"} {"pmid": "4209715", "title": "Effect of palatoplasty and cleft extent on facial and dental relations.", "content": "Effect of palatoplasty and cleft extent on facial and dental relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209715"} {"pmid": "4209714", "title": "Factors affecting fluid movement and intercellular space formation in the toad bladder.", "content": "Factors affecting fluid movement and intercellular space formation in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209714"} {"pmid": "4209716", "title": "Inhibition of inter-microbial predation by chlorinated hydrocarbons.", "content": "Inhibition of inter-microbial predation by chlorinated hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209716"} {"pmid": "4209717", "title": "Effect of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid on glutamate uptake by synaptosomes.", "content": "Effect of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid on glutamate uptake by synaptosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209717"} {"pmid": "4209718", "title": "Coronary bypass grafts.", "content": "Coronary bypass grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209718"} {"pmid": "4209719", "title": "Endarterectomy in surgical treatment of coronary disease.", "content": "Endarterectomy in surgical treatment of coronary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209719"} {"pmid": "4209720", "title": "Eradication of carriage of Neisseria meningitidis in families: a study in Brazil.", "content": "Eradication of carriage of Neisseria meningitidis in families: a study in Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209720"} {"pmid": "4209721", "title": "The human fallopian tube: a laboratory model for gonococcal infection.", "content": "The human fallopian tube: a laboratory model for gonococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209721"} {"pmid": "4209723", "title": "Comparison of three agents of acute infectious nonbacterial gastroenteritis by cross-challenge in volunteers.", "content": "Comparison of three agents of acute infectious nonbacterial gastroenteritis by cross-challenge in volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209723"} {"pmid": "4209722", "title": "Gas chromatography as a potential means of diagnosing arthritis. I. Differentiation between staphylococcal, streptococcal, gonococcal, and traumatic arthritis.", "content": "Gas chromatography as a potential means of diagnosing arthritis. I. Differentiation between staphylococcal, streptococcal, gonococcal, and traumatic arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209722"} {"pmid": "4209724", "title": "Transmission of rat virus in milk of rats.", "content": "Transmission of rat virus in milk of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209724"} {"pmid": "4209725", "title": "Studies with (plus)--octanoylcarnitine in experimental diabetic ketoacidosis.", "content": "Studies with (plus)--octanoylcarnitine in experimental diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209725"} {"pmid": "4209726", "title": "Absorption of amino acids in malnourished rats.", "content": "Absorption of amino acids in malnourished rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209726"} {"pmid": "4209727", "title": "Hypergraphia in temporal lobe epilepsy.", "content": "Hypergraphia in temporal lobe epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209727"} {"pmid": "4209728", "title": "Furosemide and pentobarbital in cryogenic cerebral injury and edema.", "content": "Furosemide and pentobarbital in cryogenic cerebral injury and edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209728"} {"pmid": "4209729", "title": "Intraluminal duodenal diverticulum. A rare cause of acute pancreatitis.", "content": "Intraluminal duodenal diverticulum. A rare cause of acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209729"} {"pmid": "4209730", "title": "Fusion of the scoliotic spine in young children.", "content": "Fusion of the scoliotic spine in young children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209730"} {"pmid": "4209731", "title": "The role of genetic balance in control of transcription rate in the X-chromosomes of Drosophila melanogaster.", "content": "The role of genetic balance in control of transcription rate in the X-chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209731"} {"pmid": "4209732", "title": "Mitosis-like macronuclear division in a ciliate.", "content": "Mitosis-like macronuclear division in a ciliate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209732"} {"pmid": "4209733", "title": "The histones of the ciliated protozoan Stylonychia mytilus.", "content": "The histones of the ciliated protozoan Stylonychia mytilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209733"} {"pmid": "4209734", "title": "Leukocyte antigens of primates.", "content": "Leukocyte antigens of primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209734"} {"pmid": "4209736", "title": "Children with protein-calorie malnutrition evacuated to Gabon during the Nigerian civil war.", "content": "Children with protein-calorie malnutrition evacuated to Gabon during the Nigerian civil war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209736"} {"pmid": "4209738", "title": "Teaching better nutrition by domiciliary management of cases of protein calorie malnutrition in rural areas (a longitudinal study of clinical and economical aspects).", "content": "Teaching better nutrition by domiciliary management of cases of protein calorie malnutrition in rural areas (a longitudinal study of clinical and economical aspects).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209738"} {"pmid": "4209737", "title": "Depression of immunity in protein-calorie malnutrition: a post-mortem study.", "content": "Depression of immunity in protein-calorie malnutrition: a post-mortem study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209737"} {"pmid": "4209739", "title": "Lead poisoning. Current status of the problem facing pediatricians.", "content": "Lead poisoning. Current status of the problem facing pediatricians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209739"} {"pmid": "4209741", "title": "Spin-lattice relaxation times of imidazole protons and their relevance to NMR studies of proteins.", "content": "Spin-lattice relaxation times of imidazole protons and their relevance to NMR studies of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209741"} {"pmid": "4209740", "title": "The EEC syndrome.", "content": "The EEC syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209740"} {"pmid": "4209743", "title": "Letter: Random deviations or asynchronous DNA synthesis?", "content": "Letter: Random deviations or asynchronous DNA synthesis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209743"} {"pmid": "4209742", "title": "Reduced susceptibility to scrapie in mice after steroid administration.", "content": "Reduced susceptibility to scrapie in mice after steroid administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209742"} {"pmid": "4209744", "title": "Dominance and sexual behavior: a hypothesis.", "content": "Dominance and sexual behavior: a hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209744"} {"pmid": "4209745", "title": "The action of protein synthesis inhibitors and thyrotropin releasing factor on the ultrastructure of rat thyrotrophs.", "content": "The action of protein synthesis inhibitors and thyrotropin releasing factor on the ultrastructure of rat thyrotrophs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209745"} {"pmid": "4209746", "title": "Accurate office diagnosis of vaginitis.", "content": "Accurate office diagnosis of vaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209746"} {"pmid": "4209747", "title": "Ultrastructural changes in the bacterial vegetative endocarditis.", "content": "Ultrastructural changes in the bacterial vegetative endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209747"} {"pmid": "4209748", "title": "Proceedings: Overview of the mammary gland.", "content": "Proceedings: Overview of the mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209748"} {"pmid": "4209749", "title": "Proceedings: The mammary glands of rhesus monkeys.", "content": "Proceedings: The mammary glands of rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209749"} {"pmid": "4209751", "title": "Recovery of Neisseria meningitidis from the nasopharynx. Comparison of two techniques.", "content": "Recovery of Neisseria meningitidis from the nasopharynx. Comparison of two techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209751"} {"pmid": "4209750", "title": "Proceedings: Neuroendocrinology of lactation.", "content": "Proceedings: Neuroendocrinology of lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209750"} {"pmid": "4209752", "title": "Oculodentodigital dysplasia. Picture of the month.", "content": "Oculodentodigital dysplasia. Picture of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209752"} {"pmid": "4209753", "title": "Diphenylhydantoin--induced hepatic necrosis.", "content": "Diphenylhydantoin--induced hepatic necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209753"} {"pmid": "4209754", "title": "Quantitative scintigraphic method of estimating the circulation of cerebrospinal fluid.", "content": "Quantitative scintigraphic method of estimating the circulation of cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209754"} {"pmid": "4209756", "title": "Unit activity in accessory optic system in alert monkeys.", "content": "Unit activity in accessory optic system in alert monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209756"} {"pmid": "4209755", "title": "Cerebellopontine cisternography with a positive contrast medium.", "content": "Cerebellopontine cisternography with a positive contrast medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209755"} {"pmid": "4209757", "title": "Dose distribution analysis of moving-strip technique for abdominal irradiation using 10 MV x rays.", "content": "Dose distribution analysis of moving-strip technique for abdominal irradiation using 10 MV x rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209757"} {"pmid": "4209759", "title": "Letter: Norrie's disease.", "content": "Letter: Norrie's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209759"} {"pmid": "4209758", "title": "BB-K8: A new aminoglycoside for intravitreal injection in bacterial endophthalmitis.", "content": "BB-K8: A new aminoglycoside for intravitreal injection in bacterial endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209758"} {"pmid": "4209762", "title": "Comparative responsiveness of euthyroid and hypothyroid rat pituitary tissue to thyrotropin releasing hormone in vitro.", "content": "Comparative responsiveness of euthyroid and hypothyroid rat pituitary tissue to thyrotropin releasing hormone in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209762"} {"pmid": "4209760", "title": "Arterial infusion of 5-fluorouracil as a treatment for carcinoma of the prostate.", "content": "Arterial infusion of 5-fluorouracil as a treatment for carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209760"} {"pmid": "4209761", "title": "Enhancement and deactivation of some microsomal glycosyl transferases.", "content": "Enhancement and deactivation of some microsomal glycosyl transferases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209761"} {"pmid": "4209765", "title": "Purification and some serological properties of staphylococcal nuclease.", "content": "Purification and some serological properties of staphylococcal nuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209765"} {"pmid": "4209766", "title": "Passive electrical properties of toad urinary bladder epithelium. Intercellular electrical coupling and transepithelial cellular and shunt conductances.", "content": "Passive electrical properties of toad urinary bladder epithelium. Intercellular electrical coupling and transepithelial cellular and shunt conductances. The electrical resistances of the transcellular and paracellular pathways across the toad urinary bladder epithelium (a typical \"tight\" sodium-transporting epithelium) were determined by two independent sets of electrophysiological measurements: (a) the measurement of the total transepithelial resistance, the ratio of resistance of the apical to the basal cell membrane, and cable analysis of the voltage spread into the epithelium; (b) the measurement of the total transepithelial resistance and the ratio of resistances of both cell membranes before and after replacing all mucosal sodium with potassium (thus, increasing selectively the resistance of the apical membrane). The results obtained with both methods indicate the presence of a finite transepithelial shunt pathway, whose resistance is about 1.8 times the resistance of the transcellular pathway. Appropriate calculations show that the resistance of the shunt pathway is almost exclusively determined by the zonula occludens section of the limiting junctions. The mean resistance of the apical cell membrane is 1.7 times that of the basal cell membrane. The use of nonconducting materials on the mucosal side allowed us to demonstrate that apparently all epithelial cells are electrically coupled, with a mean space constant of 460 microm, and a voltage spread consistent with a thin sheet model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209766"} {"pmid": "4209767", "title": "Gonogrow, an improved, selective medium for the isolation of Neisseria gonorrhoeae.", "content": "Gonogrow, an improved, selective medium for the isolation of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209767"} {"pmid": "4209768", "title": "Evaluation of skin cleansing procedures using the wipe-rinse technique.", "content": "Evaluation of skin cleansing procedures using the wipe-rinse technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209768"} {"pmid": "4209769", "title": "The use of sodium sulfite as a neutralizer for evaluating povidone-iodine preparations.", "content": "The use of sodium sulfite as a neutralizer for evaluating povidone-iodine preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209769"} {"pmid": "4209770", "title": "Fracture of the talus. A study of its genesis and morphology based upon cases with associated ankle fracture.", "content": "Fracture of the talus. A study of its genesis and morphology based upon cases with associated ankle fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209770"} {"pmid": "4209771", "title": "Rupture of the posterior talotibial ligament with the avulsion of a bone fragment from the talus.", "content": "Rupture of the posterior talotibial ligament with the avulsion of a bone fragment from the talus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209771"} {"pmid": "4209772", "title": "Cardiohemodynamic effects of nitroglycerin and several vasodilators.", "content": "Cardiohemodynamic effects of nitroglycerin and several vasodilators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209772"} {"pmid": "4209773", "title": "Angina pectoris induced by intravenous administration of 50 per cent glucose.", "content": "Angina pectoris induced by intravenous administration of 50 per cent glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209773"} {"pmid": "4209774", "title": "Thymineless death in Bacillus subtilis: correlation between cell lysis and deoxyribonucleic acid breakdown.", "content": "Thymineless death in Bacillus subtilis: correlation between cell lysis and deoxyribonucleic acid breakdown. Bacillus subtilis carrying an inducible defective phage is several times more sensitive to thymineless death than a mutagenized derivative that behaves as a nonlysogen. When the integrity of the deoxyribonucleic acid (DNA) of both strains was examined during thymine starvation by transformation experiments, sedimentation studies, and measurements of acid-soluble DNA degradation products, it was shown that extensive DNA breakdown occurred only in the lysogenic strain. During thymine starvation of this strain, there is a progressive proclivity to lysis, followed by leakage of DNA and DNA degradation products. Such leakage was not observed in the nonlysogen. A correlation between proclivity to lysis and extensive DNA degradation is indicated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209774"} {"pmid": "4209775", "title": "Sensitivity of an early step in the sporulation of Bacillus subtilis to selective inhibition by ethidium bromide.", "content": "Sensitivity of an early step in the sporulation of Bacillus subtilis to selective inhibition by ethidium bromide. When a final concentration of 0.4 mug of ethidium bromide (EB) per ml, which is subinhibitory to vegetative growth, is added to sporulating cells of Bacillus subtilis Marburg during either stage 0 or the early part of stage 1, morphogenesis is blocked. If the given concentration of EB is added after the early part of stage 1, sporogenesis is unaffected. The synthesis of the serine protease and antibiotic, which are believed to be associated with sporulation events during the early part of stage 0, are not inhibited by EB. Enhanced binding of [(14)C]benzylpenicillin to sporulating cells during septation (stage 2) is a measure of the presence of terminal enzymes for germ cell wall peptidoglycan synthesis. EB does not interfere with the binding of penicillin to sporulating cells, but penicillin remains more permanently bound to EB-treated postlogarithmic cells than to untreated sporulating cells. The absence of an interval of increased penicillin binding activity during stage 2 by sporulating cells treated with EB indicates that EB blocks sporulation prior to the completion of the germ cell wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209775"} {"pmid": "4209776", "title": "Adenine nucleotide changes associated with the initiation of sporulation in Bacillus subtilis.", "content": "Adenine nucleotide changes associated with the initiation of sporulation in Bacillus subtilis. At the end of the exponential growth phase of Bacillus subtilis, there is a decrease in the energy level of the cell, whether expressed as adenosine triphosphate concentration or adenylate energy charge. Phosphate limitation of exponentially growing cells produces a similar decrease in the energy level of the cell, and sporulation is derepressed in the presence of 10 mM glucose. A reduction in the tryptophan concentration of the medium during phosphate limitation of the tryptophan auxotroph B. subtilis 168 prevented the decrease in energy charge. Cells do not sporulate under these conditions. Energy charge values of 0.30 to 0.35 found during sporulation do not lead to cell death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209776"} {"pmid": "4209777", "title": "Nitrogenase activity and photosynthesis in Plectonema boryanum.", "content": "Nitrogenase activity and photosynthesis in Plectonema boryanum. Nitrogen-starved Plectonema boryanum 594 cultures flushed with N(2)/CO(2) or A/CO(2) (99.7%/0.3%, vol/vol) exhibited nitrogenase activity when assayed either by acetylene reduction or hydrogen evolution. Oxygen evolution activities and phycocyanin pigments decreased sharply before and during the development of nitrogenase activity, but recovered in the N(2)/CO(2) cultures after a period of active nitrogen fixation. Under high illumination, the onset of nitrogenase activity was delayed; however, the presence of 3-(3, 4-dichlorophenyl)-1, 1-dimethylurea (DCMU) eliminated this lag. Oxygen was a strong and irreversible inhibitor of nitrogenase activity at low (>0.5%) concentrations. In the dark, low oxygen tensions (0.5%) stimulated nitrogenase activity (up to 60% of that in the light), suggesting a limited but significant respiratory protection of nitrogenase at low oxygen tensions. DCMU was not a strong inhibitor of nitrogenase activity. A decrease in nitrogenase activity after a period of active nitrogen fixation was observed in the N(2)/CO(2-), but not in the A/CO(2-), flushed cultures. We suggest that this decrease in nitrogenase activity is due to exhaustion of stored substrate reserves as well as inhibition by the renewed oxygen evolution of the cultures. Repeated peaks of alternating nitrogenase activity and oxygen evolution were observed in some experiments. Our results indicate a temporal separation of these basically incompatible reactions in P. boryanum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209777"} {"pmid": "4209779", "title": "Salivary Pseudomonas aeruginosa.", "content": "Salivary Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209779"} {"pmid": "4209780", "title": "Mechanism of inhibition of bacterial growth by adenine.", "content": "Mechanism of inhibition of bacterial growth by adenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209780"} {"pmid": "4209782", "title": "The stability of taka-amylase A immobilized on various sizes of matrix.", "content": "The stability of taka-amylase A immobilized on various sizes of matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209782"} {"pmid": "4209778", "title": "Septum formation in Escherichia coli: characterization of septal structure and the effects of antibiotics on cell division.", "content": "Septum formation in Escherichia coli: characterization of septal structure and the effects of antibiotics on cell division. Septa can be demonstrated in sections of Escherichia coli strains B and B/r after fixation with acrolein and glutaraldehyde. The septum consists of an ingrowth of the cytoplasmic membrane and the mucopeptide layer; the outer membrane is excluded from the septum until the cells begin to separate. Mesosomes have also been observed. The septum is highly labile and, except in the chain-forming strains, E. coli D22 env A and CRT 97, not easily preserved by standard procedures. The labile nature of the septum may be due to the presence of autolysin(s) located at the presumptive division site. Blocking division by addition of ampicillin (2 to 5 mug/ml) to cells of E. coli B/r produces a bulge at the middle of the cells; bulge formation is stopped by addition of chloramphenicol. Cephalosporins also induce bulge formation but may stop cell elongation as well as division. Bulge formation, due to the presumed action of an autolysin(s), may be an initial step in the septation sequence when the mucopeptide is modified to allow construction of the septum. In a nonseptate filament-forming strain, PAT 84, which ceases to divide at 42 C, bulge formation only occurs in the presence of ampicillin at the time of a shift-down at 30 C or at 42 C in the presence of NaCl (0.25 to 0.34 M). Experiments with chloramphenicol suggest that the filaments are fully compartmentalized but fail to divide owing to the inactivation, rather than loss of synthesis, of an autolysin at 42 C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209778"} {"pmid": "4209781", "title": "Separation of transfer RNA's from Bacillus subtilis, Bacillus stearothermophilus and chicken liver by polyacrylamide gel electrophoresis.", "content": "Separation of transfer RNA's from Bacillus subtilis, Bacillus stearothermophilus and chicken liver by polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209781"} {"pmid": "4209783", "title": "Partial purification and some properties of cyclamate sulfamatase.", "content": "Partial purification and some properties of cyclamate sulfamatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209783"} {"pmid": "4209784", "title": "Evidence for the role of disulfide bonds in the masking of chromophore groups in bovine kappa-casein.", "content": "Evidence for the role of disulfide bonds in the masking of chromophore groups in bovine kappa-casein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209784"} {"pmid": "4209787", "title": "Interspecific variability of red cell phosphoglycerate kinase in primates.", "content": "Interspecific variability of red cell phosphoglycerate kinase in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209787"} {"pmid": "4209789", "title": "Clinical significance of native DNA antibodies in systemic lupus erythematosus and other connective tissue diseases.", "content": "Clinical significance of native DNA antibodies in systemic lupus erythematosus and other connective tissue diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209789"} {"pmid": "4209790", "title": "Hperglycaemic hyperosmolar non-ketotic metabolic decompensation in diabetes.", "content": "Hperglycaemic hyperosmolar non-ketotic metabolic decompensation in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209790"} {"pmid": "4209797", "title": "The characterization of a Bacillus capable of blue-green bactericidal activity.", "content": "The characterization of a Bacillus capable of blue-green bactericidal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209797"} {"pmid": "4209796", "title": "Induction of the L-phase of Listeria monocytogenes by rabbit alveolar macrophages in vitro.", "content": "Induction of the L-phase of Listeria monocytogenes by rabbit alveolar macrophages in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209796"} {"pmid": "4209785", "title": "Recent advances in parenteral nutrition.", "content": "Recent advances in parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209785"} {"pmid": "4209798", "title": "Aliphatic alcohols and bacterial motile behavior.", "content": "Aliphatic alcohols and bacterial motile behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209798"} {"pmid": "4209804", "title": "Glycolipids of urinary tract transitional epithelium.", "content": "Glycolipids of urinary tract transitional epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209804"} {"pmid": "4209813", "title": "Studies on the degradation of sym-homospermidine by Pseudomonas aeruginosa.", "content": "Studies on the degradation of sym-homospermidine by Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209813"} {"pmid": "4209814", "title": "Proceedings: Secretion of airway in anaphylactic shock and the effect of certain drugs.", "content": "Proceedings: Secretion of airway in anaphylactic shock and the effect of certain drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209814"} {"pmid": "4209815", "title": "Secondary respiratory infection in hospital patients: effect of antimicrobial agents and environment.", "content": "Secondary respiratory infection in hospital patients: effect of antimicrobial agents and environment. A prospective study of 358 medical and 234 postoperative patients with clinical evidence of secondary chest infection showed that previous administration of antimicrobial agents greatly reduced the chance of obtaining a clear-cut laboratory report. In patients with radiographical evidence of pneumonia this led to a fourfold decrease in the overall rate of isolation of potential pathogens. Furthermore, 81 diverse \"coliforms\" were isolated from 258 medical and surgical patients who had received previous antimicrobial therapy while only four coliforms (all Escherichia coli) were isolated from 334 untreated patients. Thus the general hospital environment on its own seemed to have a negligible influence in promoting the growth of coliform flora in sputum. Any unique effect of underlying disease in this regard was masked by that of previous therapy. Finally, the results raised the possibility that previous antimicrobial therapy might have increased the risk of secondary pneumonia in hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209815"} {"pmid": "4209817", "title": "Use of elemental diets to correct catabolic states prior to surgery.", "content": "Use of elemental diets to correct catabolic states prior to surgery. An elemental diet was used to prepare 11 severely debilitated malnourished patients for operation. Indications included: 1) as a substitute for parenteral hyperalimentation when catheter sepsis occurred with the latter; 2) high small fistulae; 3) short bowel syndrome; 4) radiation enteritis; and 5) partial obstruction of the gastrointestinal tract. All patients were converted to a positive nitrogen balance as evidenced by a substantial gain in weight and in serum albumin levels. All tolerated corrective operations without difficulty and their wounds healed per primum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209817"} {"pmid": "4209818", "title": "Serum antibody in patients with breast disease: Correlation with histopathology.", "content": "Serum antibody in patients with breast disease: Correlation with histopathology. Antibody to a breast cancer antigen was detected by immunodiffusion or complement fixation in at least one serum sample in 46% of 84 patients with a diagnosis of carcinoma, 34% of 96 patients with fibrocystic disease and 25% of 44 patients with fibroadenoma. A single serum sample obtained from screenees of the Detection Center for Breast Diseases was tested by immunodiffusion only and antibody was found in 3 of 206 screenees (1.5%). Eleven of 13 patients with breast cancer metastatic to lymph nodes and no detectable serum antibody either had recurrence or were dead within 12 months of mastectomy. Fifteen of 18 patients with breast cancer metastatic to lymph nodes and with detectable serum antibody were alive and free of disease for up to 24 months. Histologic slides from patients with a diagnosis of fibrocystic disease or fibroadenoma were reviewed for the presence of ductal epithelial hyperplasia. Ductal epithelial hyperplasia was present in a similar per cent of patients with no detectable serum antibody as those with antibody detected in the serum. Severe sinus histiocytosis of the axillary lymph nodes was present in 45% of those cancer patients with serum antibody and only 11% of those cancer patients with no detectable serum antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209818"} {"pmid": "4209820", "title": "Unresponsiveness of exocrine rat pancreas to calcemic challenges (hypercalcemia, EDTA hypocalcemia or calcitonin administration) which influence stomach function.", "content": "Unresponsiveness of exocrine rat pancreas to calcemic challenges (hypercalcemia, EDTA hypocalcemia or calcitonin administration) which influence stomach function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209820"} {"pmid": "4209821", "title": "Origin of cerebellar climbing fibers in the rhesus monkey.", "content": "Origin of cerebellar climbing fibers in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209821"} {"pmid": "4209822", "title": "Evaluation of genetic structure of Drosophila melanogaster population with respect to the characteristic radius incompletus. Report II. Verification of Wright and Fisher systems.", "content": "Evaluation of genetic structure of Drosophila melanogaster population with respect to the characteristic radius incompletus. Report II. Verification of Wright and Fisher systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209822"} {"pmid": "4209816", "title": "Contamination of cord blood with maternal blood during delivery.", "content": "Contamination of cord blood with maternal blood during delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209816"} {"pmid": "4209825", "title": "The fine structure of cysts of Frenkelia (the M-organism).", "content": "The fine structure of cysts of Frenkelia (the M-organism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209825"} {"pmid": "4209826", "title": "The age of Ixodes ricinus ticks as a factor of their susceptibility to pp-DDT, imidan and carbaryl.", "content": "The age of Ixodes ricinus ticks as a factor of their susceptibility to pp-DDT, imidan and carbaryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209826"} {"pmid": "4209827", "title": "Inactivation of allantoinase of Pseudomonas aeruginosa in vivo.", "content": "Inactivation of allantoinase of Pseudomonas aeruginosa in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209827"} {"pmid": "4209831", "title": "Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. II. The effects of inhibitors of protein synthesis.", "content": "Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. II. The effects of inhibitors of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209831"} {"pmid": "4209834", "title": "Monolayer mass culture on disposable plastic spirals.", "content": "Monolayer mass culture on disposable plastic spirals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209834"} {"pmid": "4209832", "title": "EM49, a new peptide antibiotic. 3. biological characterization in vitro and in vivo.", "content": "EM49, a new peptide antibiotic. 3. biological characterization in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209832"} {"pmid": "4209836", "title": "Suppression of tumor growth and regression of established tumor with oil-attached mycobacterial fractions.", "content": "Suppression of tumor growth and regression of established tumor with oil-attached mycobacterial fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209836"} {"pmid": "4209835", "title": "Distribution and excretion of cyclocytidine in monkeys, dogs, and rats.", "content": "Distribution and excretion of cyclocytidine in monkeys, dogs, and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209835"} {"pmid": "4209837", "title": "DNA reassociation kinetics of closely related species.", "content": "DNA reassociation kinetics of closely related species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209837"} {"pmid": "4209838", "title": "Intercellular adhesion: modification by dielectric properties of the medium.", "content": "Intercellular adhesion: modification by dielectric properties of the medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209838"} {"pmid": "4209839", "title": "Changes in serum thyroxine-binding proteins in endemic goitre and endemic cretinism.", "content": "Changes in serum thyroxine-binding proteins in endemic goitre and endemic cretinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209839"} {"pmid": "4209840", "title": "A comparison of effective thyroxine ratio, free thyroxine index and free thyroxine concentration in correcting for thyroxine-binding abnormalities in serum.", "content": "A comparison of effective thyroxine ratio, free thyroxine index and free thyroxine concentration in correcting for thyroxine-binding abnormalities in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209840"} {"pmid": "4209841", "title": "The clinical application of a new prosthetic arteriovenous shunt. Characteristics and advantages over the standard A-V shunt and the A-V fistula.", "content": "The clinical application of a new prosthetic arteriovenous shunt. Characteristics and advantages over the standard A-V shunt and the A-V fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209841"} {"pmid": "4209843", "title": "Prevention of induced autophagy by emetine in exocrine cells of mouse pancreas and seminal vesicle.", "content": "Prevention of induced autophagy by emetine in exocrine cells of mouse pancreas and seminal vesicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209843"} {"pmid": "4209842", "title": "Isolation and partial characterization of the internal structural proteins from murine intracisternal A particles.", "content": "Isolation and partial characterization of the internal structural proteins from murine intracisternal A particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209842"} {"pmid": "4209844", "title": "Fine structural alterations in mesothelial cells associated with cardiac anomaly.", "content": "Fine structural alterations in mesothelial cells associated with cardiac anomaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209844"} {"pmid": "4209845", "title": "Nuclear fibrous lamina in pathological human synovial membrane.", "content": "Nuclear fibrous lamina in pathological human synovial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209845"} {"pmid": "4209848", "title": "The behavior of delta-aminolevulinic acid levels in the blood of patients on regular dialysis treatment (RDT).", "content": "The behavior of delta-aminolevulinic acid levels in the blood of patients on regular dialysis treatment (RDT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209848"} {"pmid": "4209850", "title": "On the effects of tricarboxylic acid cycle intermediates on sodium transport by the toad bladder.", "content": "On the effects of tricarboxylic acid cycle intermediates on sodium transport by the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209850"} {"pmid": "4209861", "title": "Ketogenesis and the Indian diabetic.", "content": "Ketogenesis and the Indian diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209861"} {"pmid": "4209862", "title": "Letter: Hyperamylasemia and diabetic ketoacidosis.", "content": "Letter: Hyperamylasemia and diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209862"} {"pmid": "4209864", "title": "Relationship of delayed-type hypersensitivity and acquired cellular resistance in experimental airborne tuberculosis.", "content": "Relationship of delayed-type hypersensitivity and acquired cellular resistance in experimental airborne tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209864"} {"pmid": "4209863", "title": "Specific human antibodies to enterotoxins A, B, and C1 of Staphylococcus: their increased synthesis in staphylococcal infection.", "content": "Specific human antibodies to enterotoxins A, B, and C1 of Staphylococcus: their increased synthesis in staphylococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209863"} {"pmid": "4209865", "title": "Letter: Alcohol and the liver.", "content": "Letter: Alcohol and the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209865"} {"pmid": "4209866", "title": "Multiple gene sites for 5S and 18 plus 28S RNA on chromosomes of Glyptotendipes barbipes (Staeger).", "content": "Multiple gene sites for 5S and 18 plus 28S RNA on chromosomes of Glyptotendipes barbipes (Staeger). Ribosomal RNAs (28 + 18S and 5S) and 4S RNA extracted from the chironomid Glyptotendipes barbipes were iodinated in vitro with (125)I and hybridized to the salivary gland chromosomes of G. barbipes and Drosophila melanogaster. Iodinated 18 + 28 S RNA labeled three puffed sites with associated nucleoli on chromosomes IR, IIL, and IIIL of G. barbipes and the nucleolar organizer of Drosophila. Labeled 5S RNA hybridized to three sites on chromosome IIIR, two sites on chromosome IIR and one site in a Balbiani ring on chromosome IV of Glyptotendipes. Most of the label produced by this RNA was localized seven bands away from the centromere on the right arm of chromosome III, and we consider this to be the main site complementary to 5S RNA in the chironomid. This same RNA preparation specifically labeled the 56 EF region of chromosome IIR of Drosophila which has been shown previously to be the only site labeled when hybridized with homologous 5S RNA. Hybridization of G. barbipes chromosomes with iodinated 4S RNA produced no clearly localized labeled sites over the exposure periods studied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209866"} {"pmid": "4209868", "title": "The structural basis of selective gene expression in eukaryotes.", "content": "The structural basis of selective gene expression in eukaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209868"} {"pmid": "4209867", "title": "Thrombin substrates and the proteolytic site of thrombin action on human-platelet plasma membranes.", "content": "Thrombin substrates and the proteolytic site of thrombin action on human-platelet plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209867"} {"pmid": "4209870", "title": "Effect of unilateral visual deprivation on the activities of acetylcholinesterase, cholinesterase and carbonic anhydrase of the optic lobe of pigeon.", "content": "Effect of unilateral visual deprivation on the activities of acetylcholinesterase, cholinesterase and carbonic anhydrase of the optic lobe of pigeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209870"} {"pmid": "4209871", "title": "Editorial: Blind children.", "content": "Editorial: Blind children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209871"} {"pmid": "4209872", "title": "Urinary excretion of fibrinogen-related materials, complement, and immunoglobulins in proliferative glomerulonephritis and after renal transplantation.", "content": "Urinary excretion of fibrinogen-related materials, complement, and immunoglobulins in proliferative glomerulonephritis and after renal transplantation. Using a radial immunodiffusion technique we measured the urinary concentration of material related to complement (C3), IgM, and IgG along with fibrin-fibrinogen degradation products and heterophile (sheep) haemagglutinins in 15 patients with proliferative glomerulonephritis and in 10 patients after renal transplantation. There was a significant correlation between all variables measured, and serial studies showed that with the exception of IgG-related materials potentially useful information could be obtained on the detection of rejection and the response to treatment in both conditions. The significance of these observations is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209872"} {"pmid": "4209874", "title": "Prolactin response to thyrotrophin releasing hormone in thyrotoxicosis.", "content": "Prolactin response to thyrotrophin releasing hormone in thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209874"} {"pmid": "4209873", "title": "Effects of vasopressin on toad bladder membrane proteins: relationship to transport of sodium and water.", "content": "Effects of vasopressin on toad bladder membrane proteins: relationship to transport of sodium and water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209873"} {"pmid": "4209875", "title": "Editorial: Facial hyperkinesis.", "content": "Editorial: Facial hyperkinesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209875"} {"pmid": "4209876", "title": "Artificial feeding of prisoners.", "content": "Artificial feeding of prisoners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209876"} {"pmid": "4209877", "title": "Inquest on hunger-striker.", "content": "Inquest on hunger-striker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209877"} {"pmid": "4209878", "title": "The agar gel double diffusion test for detection of the Australia antigen.", "content": "The agar gel double diffusion test for detection of the Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209878"} {"pmid": "4209881", "title": "On the chemical aspects of penicillin activity.", "content": "On the chemical aspects of penicillin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209881"} {"pmid": "4209880", "title": "The influence of dietary intake on endogenous acid production. Theoretical and experimental background.", "content": "The influence of dietary intake on endogenous acid production. Theoretical and experimental background.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209880"} {"pmid": "4209883", "title": "Synthesis of von Willebrand factor by cultured human endothelial cells.", "content": "Synthesis of von Willebrand factor by cultured human endothelial cells. Cultured human endothelial cells synthesize and secrete a protein(s) which has Factor VIII antigen but which lacks Factor VIII clot-promoting activity (J. Clin. Invest. 52, 2757-2764, 1973). Von Willebrand factor activity has been identified in medium from cultured human endothelial cells. This activity was demonstrated by the ability to correct the defect in platelet adhesiveness of blood obtained from patients with von Willebrand's disease. This activity also supported ristocetin-induced aggregation of washed normal human platelets. The von Willebrand factor activity from cultured endothelial cells has physicochemical and immunologic properties like those of the von Willebrand factor activity and the Factor VIII antigen present in human plasma and the Factor VIII antigen synthesized by human endothelial cells in vitro. Rabbit antibody to chromatographic fractions containing endothelial cell von Willebrand factor inhibits the platelet retention of normal blood in glass bead columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209883"} {"pmid": "4209886", "title": "Effect of the lesion of the mammillary bodies on the performance in the open field.", "content": "Effect of the lesion of the mammillary bodies on the performance in the open field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209886"} {"pmid": "4209888", "title": "Studies on the activated sludge bacteria participating in the biodegradation of methanol, formaldehyde and ethylene glycol. I. Isolation and identification.", "content": "Studies on the activated sludge bacteria participating in the biodegradation of methanol, formaldehyde and ethylene glycol. I. Isolation and identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209888"} {"pmid": "4209889", "title": "Studies on the activated sludge bacteria participating in the biodegradation of methanol, formaldehyde and ethylene glycol. II. Utilization of various carbon and nitrogen compounds.", "content": "Studies on the activated sludge bacteria participating in the biodegradation of methanol, formaldehyde and ethylene glycol. II. Utilization of various carbon and nitrogen compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209889"} {"pmid": "4209891", "title": "35Cl nuclear magnetic resonance study of zinc and phosphate binding of E. coli alkaline phosphatase.", "content": "35Cl nuclear magnetic resonance study of zinc and phosphate binding of E. coli alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209891"} {"pmid": "4209893", "title": "Protomer stability and sclerotization in vitro.", "content": "Protomer stability and sclerotization in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209893"} {"pmid": "4209892", "title": "An immunochemical study of the calcium ion-binding protein (troponin-C) and the inhibitory protein (troponin-I) of the troponin complex and their interaction.", "content": "An immunochemical study of the calcium ion-binding protein (troponin-C) and the inhibitory protein (troponin-I) of the troponin complex and their interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209892"} {"pmid": "4209894", "title": "Distribution of microtubules in the golgi apparatus of Euglena gracilis.", "content": "Distribution of microtubules in the golgi apparatus of Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209894"} {"pmid": "4209895", "title": "Plasticity of cortical cell firing patterns after load changes.", "content": "Plasticity of cortical cell firing patterns after load changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209895"} {"pmid": "4209896", "title": "The membrane surfaces of the toad bladder: scanning and transmission electron-microscopy.", "content": "The membrane surfaces of the toad bladder: scanning and transmission electron-microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209896"} {"pmid": "4209898", "title": "D2O-alanine exchange reactions catalyzed by alanine racemase and glutamic pyruvic transminase.", "content": "D2O-alanine exchange reactions catalyzed by alanine racemase and glutamic pyruvic transminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209898"} {"pmid": "4209897", "title": "Neutral proteinase of rabbit skin: an enzyme capable of degrading skin protein and inducing an inflammatory response.", "content": "Neutral proteinase of rabbit skin: an enzyme capable of degrading skin protein and inducing an inflammatory response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209897"} {"pmid": "4209899", "title": "Analytical-band centrifugation of the active form of pig kidney diamine oxidase.", "content": "Analytical-band centrifugation of the active form of pig kidney diamine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209899"} {"pmid": "4209900", "title": "Biogenesis of multiple cellulase components of Pseudomonas fluorescens var. cellulosa. I. Effects of culture conditions on the multiplicity of cellulase.", "content": "Biogenesis of multiple cellulase components of Pseudomonas fluorescens var. cellulosa. I. Effects of culture conditions on the multiplicity of cellulase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209900"} {"pmid": "4209901", "title": "Staining of myofibrils with fluorescent antibody against the 10S component of the original alpha-actinin preparation.", "content": "Staining of myofibrils with fluorescent antibody against the 10S component of the original alpha-actinin preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209901"} {"pmid": "4209903", "title": "Proceeding: The site of conduction block in peripheral nerves compressed by a pneumatic tourniquet.", "content": "Proceeding: The site of conduction block in peripheral nerves compressed by a pneumatic tourniquet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209903"} {"pmid": "4209904", "title": "Proceedings: Effect of prostaglandins on water transport across the isolated toad bladder.", "content": "Proceedings: Effect of prostaglandins on water transport across the isolated toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209904"} {"pmid": "4209905", "title": "Proceedings: The effect of ouabain, low temperature and exposure to Li solutions on cation fluxes in amphibian oocytes.", "content": "Proceedings: The effect of ouabain, low temperature and exposure to Li solutions on cation fluxes in amphibian oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209905"} {"pmid": "4209906", "title": "Proceedings: The effect of thyrotrophin releasing factor on the secretion of thyroid stimulating hormone and prolactin from the chicken anterior pituitary gland.", "content": "Proceedings: The effect of thyrotrophin releasing factor on the secretion of thyroid stimulating hormone and prolactin from the chicken anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209906"} {"pmid": "4209909", "title": "The limitations and dangers of commerciogenic nutritious foods.", "content": "The limitations and dangers of commerciogenic nutritious foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209909"} {"pmid": "4209911", "title": "HL-A antigens and some immunological parameters in psoriasis.", "content": "HL-A antigens and some immunological parameters in psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209911"} {"pmid": "4209910", "title": "The relevance of a serological classification of chronic hepatitis.", "content": "The relevance of a serological classification of chronic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209910"} {"pmid": "4209914", "title": "Chronic eosinophilic pneumonia, a manifestation of allergic aspergillosis.", "content": "Chronic eosinophilic pneumonia, a manifestation of allergic aspergillosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209914"} {"pmid": "4209915", "title": "Gastrointestinal transit time in ovarian carcinoma irradiated with 60Co.", "content": "Gastrointestinal transit time in ovarian carcinoma irradiated with 60Co.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209915"} {"pmid": "4209916", "title": "Estimation of the size of a T-cell-induced lytic lesion.", "content": "Estimation of the size of a T-cell-induced lytic lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209916"} {"pmid": "4209918", "title": "Brain activity during emotional states.", "content": "Brain activity during emotional states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209918"} {"pmid": "4209917", "title": "Effect of bicarbonate on oxygen transport in juvenile diabetic ketoacidosis.", "content": "Effect of bicarbonate on oxygen transport in juvenile diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209917"} {"pmid": "4209919", "title": "Prevention of adhesion in injury of the extensor mechanism of the fingers.", "content": "Prevention of adhesion in injury of the extensor mechanism of the fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209919"} {"pmid": "4209920", "title": "Structure activity relationship in sixteen membered macrolide antibiotics.", "content": "Structure activity relationship in sixteen membered macrolide antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209920"} {"pmid": "4209923", "title": "Potential antileprotic agents. 3. Inhibition of mycobacterial dihydrofolic reductase by 2,4-diamino-5-methyl-6-alkylquinazolines.", "content": "Potential antileprotic agents. 3. Inhibition of mycobacterial dihydrofolic reductase by 2,4-diamino-5-methyl-6-alkylquinazolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209923"} {"pmid": "4209924", "title": "Studies of prolactin and TSH secretion by continuous infusion of small amounts of thyrotropin-releasing hormone (TRH).", "content": "Studies of prolactin and TSH secretion by continuous infusion of small amounts of thyrotropin-releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209924"} {"pmid": "4209925", "title": "The use of 4-6 MeV electrons for the conservative treatment of retinoblastoma.", "content": "The use of 4-6 MeV electrons for the conservative treatment of retinoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209925"} {"pmid": "4209926", "title": "The ultrastructure of the human placental bed.", "content": "The ultrastructure of the human placental bed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209926"} {"pmid": "4209928", "title": "Diphtheria toxin and mutant proteins.", "content": "Diphtheria toxin and mutant proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209928"} {"pmid": "4209927", "title": "The surgical treatment of carcinoma of the oesophagus.", "content": "The surgical treatment of carcinoma of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209927"} {"pmid": "4209930", "title": "Enhancement of cord factor-toxicity by sulfolipid.", "content": "Enhancement of cord factor-toxicity by sulfolipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209930"} {"pmid": "4209929", "title": "Stereochemistry and toxicity of cord factor.", "content": "Stereochemistry and toxicity of cord factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209929"} {"pmid": "4209931", "title": "Evaluation of some morphological characteristics of spores of two species of Microsporida by scanning electron microscope and freeze-etching techniques.", "content": "Evaluation of some morphological characteristics of spores of two species of Microsporida by scanning electron microscope and freeze-etching techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209931"} {"pmid": "4209932", "title": "Functional and electron microscopic changes in the trabecular meshwork remaining after trabeculectomy in cynomolgus monkeys.", "content": "Functional and electron microscopic changes in the trabecular meshwork remaining after trabeculectomy in cynomolgus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209932"} {"pmid": "4209933", "title": "Failure to induce autoimmune disease with neonatal bursectomy in chickens.", "content": "Failure to induce autoimmune disease with neonatal bursectomy in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209933"} {"pmid": "4209934", "title": "Studies on the mouse mammary tumour agent (MTA). IV. Lactate and malate dehydrogenase isozymes in normal mammary gland of R3f, C57BL and in virus-induced and spontaneous mammary adenocarcinoma in C57BL and R3 mouse strains.", "content": "Studies on the mouse mammary tumour agent (MTA). IV. Lactate and malate dehydrogenase isozymes in normal mammary gland of R3f, C57BL and in virus-induced and spontaneous mammary adenocarcinoma in C57BL and R3 mouse strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209934"} {"pmid": "4209935", "title": "Distribution of alkaline phosphatase in the digestive system of a few teleost fishes.", "content": "Distribution of alkaline phosphatase in the digestive system of a few teleost fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209935"} {"pmid": "4209938", "title": "Mechanisms regulating ovarian cycle in the toad Bufo bufo bufo (L): role of presence of second growth phase oocytes in controlling recruitment from pool of first growth phase oocytes.", "content": "Mechanisms regulating ovarian cycle in the toad Bufo bufo bufo (L): role of presence of second growth phase oocytes in controlling recruitment from pool of first growth phase oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209938"} {"pmid": "4209939", "title": "Some biological and morphological characteristics of the agent 3053 LB isolated from the plasma of a leukemic cow.", "content": "Some biological and morphological characteristics of the agent 3053 LB isolated from the plasma of a leukemic cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209939"} {"pmid": "4209941", "title": "Roentgenologic determination of foetal maturity.", "content": "Roentgenologic determination of foetal maturity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209941"} {"pmid": "4209942", "title": "Microcalorimetry applied to certain species of bacteria growing in sterilized separated milk.", "content": "Microcalorimetry applied to certain species of bacteria growing in sterilized separated milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209942"} {"pmid": "4209943", "title": "Secretion of collagen by corneal epithelium. II. Effect of the underlying substratum on secretion and polymerization of epithelial products.", "content": "Secretion of collagen by corneal epithelium. II. Effect of the underlying substratum on secretion and polymerization of epithelial products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209943"} {"pmid": "4209944", "title": "Incorporation of 3H-thymidine in rhesus monkey (Macaca mulatta) embryos.", "content": "Incorporation of 3H-thymidine in rhesus monkey (Macaca mulatta) embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209944"} {"pmid": "4209945", "title": "Antibodies against Sertoli cells in human infertility.", "content": "Antibodies against Sertoli cells in human infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209945"} {"pmid": "4209946", "title": "Endogenous endotoxemia during hemorrhagic shock in the subhuman primate.", "content": "Endogenous endotoxemia during hemorrhagic shock in the subhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209946"} {"pmid": "4209947", "title": "Postoperative nutrition and colonic wound healing, serum protein metabolism, and body weight.", "content": "Postoperative nutrition and colonic wound healing, serum protein metabolism, and body weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209947"} {"pmid": "4209948", "title": "Insulin response in patients undergoing prolonged intravenous hyperalimentation.", "content": "Insulin response in patients undergoing prolonged intravenous hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209948"} {"pmid": "4209949", "title": "Cortisol responses to normotensive and hypotensive oligemia in unanesthetized primates.", "content": "Cortisol responses to normotensive and hypotensive oligemia in unanesthetized primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209949"} {"pmid": "4209950", "title": "Treatment of acute renal failure with intravenous administration of essential amino acids and glucose.", "content": "Treatment of acute renal failure with intravenous administration of essential amino acids and glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209950"} {"pmid": "4209951", "title": "Portacaval shunt in established experimental mammary carcinoma.", "content": "Portacaval shunt in established experimental mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209951"} {"pmid": "4209952", "title": "Pulmonary function studies with Xenon 133 after orthotopic cardiopulmonary autotransplantation in primates.", "content": "Pulmonary function studies with Xenon 133 after orthotopic cardiopulmonary autotransplantation in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209952"} {"pmid": "4209953", "title": "Acid and gastrin response to acute hypercalcemia in conscious monkeys.", "content": "Acid and gastrin response to acute hypercalcemia in conscious monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209953"} {"pmid": "4209955", "title": "An inhibitor, obtained from primates, of gastrin-stimulated gastric acid in rats.", "content": "An inhibitor, obtained from primates, of gastrin-stimulated gastric acid in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209955"} {"pmid": "4209954", "title": "Gastrin response to feeding.", "content": "Gastrin response to feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209954"} {"pmid": "4209956", "title": "External compression of the cardia related to gastroesophageal reflux.", "content": "External compression of the cardia related to gastroesophageal reflux.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209956"} {"pmid": "4209958", "title": "Normothermic vs hypothermic perfusion in treatment of acute experimental spinal cord injury.", "content": "Normothermic vs hypothermic perfusion in treatment of acute experimental spinal cord injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209958"} {"pmid": "4209957", "title": "Cerebral blood flow and its responsiveness to arterial PCO2: alterations before and after experimental head injury.", "content": "Cerebral blood flow and its responsiveness to arterial PCO2: alterations before and after experimental head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209957"} {"pmid": "4209959", "title": "Middle cerebral arterial spasm from subarachnoid blood: spasmolysis with topical use of nitroglycerin.", "content": "Middle cerebral arterial spasm from subarachnoid blood: spasmolysis with topical use of nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209959"} {"pmid": "4209961", "title": "Effect of cryosurgery on the tympanic membrane.", "content": "Effect of cryosurgery on the tympanic membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209961"} {"pmid": "4209960", "title": "Long-term recording of primate cochlear potentials through an inner ear electrode implant.", "content": "Long-term recording of primate cochlear potentials through an inner ear electrode implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209960"} {"pmid": "4209962", "title": "Correlation between buccal smear abnormalities and serum protein levels in infants suffering from protein calorie malnutrition and vitamin A deficiency.", "content": "Correlation between buccal smear abnormalities and serum protein levels in infants suffering from protein calorie malnutrition and vitamin A deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209962"} {"pmid": "4209963", "title": "Non-reciprocal intragenic mitotic recombination in Drosophila melanogaster.", "content": "Non-reciprocal intragenic mitotic recombination in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209963"} {"pmid": "4209964", "title": "The genetics of some second chromosome melanotic tumour mutants of Drosophila melanogaster.", "content": "The genetics of some second chromosome melanotic tumour mutants of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209964"} {"pmid": "4209967", "title": "Glycoside conjugative activity in different insect and vertebrate species.", "content": "Glycoside conjugative activity in different insect and vertebrate species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209967"} {"pmid": "4209968", "title": "Detection of metabolic carcinogen intermediates in urine of carcinogen-fed rats by means of bacterial mutagenesis.", "content": "Detection of metabolic carcinogen intermediates in urine of carcinogen-fed rats by means of bacterial mutagenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209968"} {"pmid": "4209969", "title": "Nitroglycerin-induced suppression of excitation of afferent cardiac sympathetic nerves during myocardial ischemia.", "content": "Nitroglycerin-induced suppression of excitation of afferent cardiac sympathetic nerves during myocardial ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209969"} {"pmid": "4209970", "title": "Regulation of neutral protease productivity in Bacillus subtilis: transformation of high protease productivity.", "content": "Regulation of neutral protease productivity in Bacillus subtilis: transformation of high protease productivity. A transformable strain of Bacillus subtilis 6160, a derivative of B. subtilis 168, produces three kinds of casein hydrolytic enzymes (alkaline protease, neutral protease, and esterase) in a culture medium. B. natto IAM 1212 produces 15 to 20 times as much total proteolytic activity as does B. subtilis. Extracellular proteases produced by the two strains were separated into each enzyme fraction by diethylaminoethyl-Sephadex A-50 column chromatography. The difference in the total protease activities of extracellular proteases between the two strains was due to the amount of neutral protease. The ratios of neutral protease activity to alkaline protease activity (N/A) were 1.1 in B. subtilis 6160 and 13.0 in B. natto IAM 1212. Enzymological and immunological properties of alkaline protease and neutral protease obtained from the two strains were quite similar or identical, respectively. Specific activities measured by an immunological analysis of the two neutral proteases against casein were also equal. A genetic character of high protease productivity in B. natto IAM 1212 was transferred to B. subtilis 6160 by the deoxyribonucleic acid-mediated transformation. Among 73 transformants that acquired high protease productivity, 69 produced a higher amount of neutral protease and the ratios of N/A were changed to 15 to 60. Three other strains were transformed in the productivity of neutral protease and alpha-amylase simultaneously, and one showed considerable change in the production of alkaline protease and neutral protease. The specific activities (casein hydrolytic activities/enzyme molecules) of neutral proteases from the representative four transformants were equal to those of the two parental strains. These results suggested the presence of a specific gene(s) that participated in the productivity of neutral protease in B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209970"} {"pmid": "4209971", "title": "Protein-calorie malnutrition. A host determinant for Pneumocystis carinii infection.", "content": "Protein-calorie malnutrition. A host determinant for Pneumocystis carinii infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209971"} {"pmid": "4209972", "title": "Further investigations on pulsatile movements in the cerebrospinal fluid pathways.", "content": "Further investigations on pulsatile movements in the cerebrospinal fluid pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209972"} {"pmid": "4209973", "title": "The healing of experimentally induced pulpitis.", "content": "The healing of experimentally induced pulpitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209973"} {"pmid": "4209974", "title": "M-protein.", "content": "M-protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209974"} {"pmid": "4209976", "title": "Problems of immunology in myasthenia, polymyositis and Guillain-Barré syndrome.", "content": "Problems of immunology in myasthenia, polymyositis and Guillain-Barré syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209976"} {"pmid": "4209982", "title": "Immunoglobulins of the Indian buffalo.", "content": "Immunoglobulins of the Indian buffalo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209982"} {"pmid": "4209983", "title": "Absorption spectra of algal and chloroplast suspensions: a simple method using conventional spectrophotometers.", "content": "Absorption spectra of algal and chloroplast suspensions: a simple method using conventional spectrophotometers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209983"} {"pmid": "4209985", "title": "Letter: Biological effects of azomycin (2-nitro-imidazole): inhibition of ribonucleotide reductase.", "content": "Letter: Biological effects of azomycin (2-nitro-imidazole): inhibition of ribonucleotide reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209985"} {"pmid": "4209989", "title": "Antibody deficiency syndromes in children. Analysis of serum immunoglobulins in 1170 hospitalized children.", "content": "Antibody deficiency syndromes in children. Analysis of serum immunoglobulins in 1170 hospitalized children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209989"} {"pmid": "4209990", "title": "Chromatographic separation and serologic analysis of antibodies in the sera of mothers with ABO incompatibility.", "content": "Chromatographic separation and serologic analysis of antibodies in the sera of mothers with ABO incompatibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209990"} {"pmid": "4209991", "title": "Influence of Corynebacterium diphtheriae and pseudodiphtheriae on embryonic quinea pig cell cultures. II. Ultrastructural studies on infected culture cells.", "content": "Influence of Corynebacterium diphtheriae and pseudodiphtheriae on embryonic quinea pig cell cultures. II. Ultrastructural studies on infected culture cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209991"} {"pmid": "4209992", "title": "Enzymatic repair of deoxyribonucleic acid; the biochemical and biological repair properties of a deoxyribonucleic acid polymerase from micrococcus luteus.", "content": "Enzymatic repair of deoxyribonucleic acid; the biochemical and biological repair properties of a deoxyribonucleic acid polymerase from micrococcus luteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209992"} {"pmid": "4209994", "title": "The enzymic and non-enzymic degradation of colneleic acid, an unsaturated fatty acid ether intermediate in the lipoxygenase pathway of linoleic acid oxidation in potato (Solanum tuberosum) tubers.", "content": "The enzymic and non-enzymic degradation of colneleic acid, an unsaturated fatty acid ether intermediate in the lipoxygenase pathway of linoleic acid oxidation in potato (Solanum tuberosum) tubers. Colneleic acid is an unsaturated ether fatty acid derived from linoleic acid via a lipoxygenase-mediated enzyme pathway. It is degraded (a) by an enzyme in potato tubers which is heat-labile and non-dialysable and (b) by a model system containing catalytic amounts of Fe(2+) ions. Both enzyme- and Fe(2+)-catalysed systems have similar properties with respect to pH optima (pH5.0-5.5), oxygen requirement (0.6-0.7 mol of O(2) consumed/mol of ether degraded), inhibitors and reaction products. An unstable product breaks down to C(8) and C(9) carbonyl fragments. Both systems are inhibited by low concentrations of antioxidants (e.g. 5mum-butylated hydroxytoluene) and some chelating agents (e.g. 5mum-diethyldithio-carbamate). The model system is strongly inhibited by metal ions, particularly Cu(2+) and Fe(3+), at 20mum. Hydrogen peroxide and haemoproteins do not substitute for the enzyme or Fe(2+) ions but the non-haem iron protein, ferredoxin, does catalyse the degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209994"} {"pmid": "4209999", "title": "New problems in sonar diagnosis in obstetrics and gynecology.", "content": "New problems in sonar diagnosis in obstetrics and gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209999"} {"pmid": "4210000", "title": "Pathophysiology of Salmonella diarrhea in the Rhesus monkey: Intestinal transport, morphological and bacteriological studies.", "content": "Pathophysiology of Salmonella diarrhea in the Rhesus monkey: Intestinal transport, morphological and bacteriological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210000"} {"pmid": "4210001", "title": "A physiological model to study gallbladder function in primates.", "content": "A physiological model to study gallbladder function in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210001"} {"pmid": "4210002", "title": "Letter: Long-term parenteral nutrition.", "content": "Letter: Long-term parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210002"} {"pmid": "4210004", "title": "Letter: Pheochromocytoma and hyperparathyroidism.", "content": "Letter: Pheochromocytoma and hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210004"} {"pmid": "4210003", "title": "Cost of medical care in a practice of internal medicine. A study in a group of seven internists.", "content": "Cost of medical care in a practice of internal medicine. A study in a group of seven internists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210003"} {"pmid": "4210005", "title": "Amoxicillin: in vitro susceptibility of \"blood culture strains\" of gram-negative bacilli and comparisons with penicillin G ampicillin, and carbenicillin.", "content": "Amoxicillin: in vitro susceptibility of \"blood culture strains\" of gram-negative bacilli and comparisons with penicillin G ampicillin, and carbenicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210005"} {"pmid": "4210007", "title": "Determination of blood acetylcholinesterase inhibition caused by reversible inhibitors in vivo.", "content": "Determination of blood acetylcholinesterase inhibition caused by reversible inhibitors in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210007"} {"pmid": "4210006", "title": "Amoxicillin in the treatment of uncomplicated gonococcal urethritis in males.", "content": "Amoxicillin in the treatment of uncomplicated gonococcal urethritis in males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210006"} {"pmid": "4210008", "title": "Minicells of Bacillus subtilis. A unique system for transport studies.", "content": "Minicells of Bacillus subtilis. A unique system for transport studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210008"} {"pmid": "4210009", "title": "Letter: Acute brucellosis presenting as epididymo-orchitis.", "content": "Letter: Acute brucellosis presenting as epididymo-orchitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210009"} {"pmid": "4210011", "title": "Contamination of blood cultures from a commercial beta-lactamase preparations.", "content": "Contamination of blood cultures from a commercial beta-lactamase preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210011"} {"pmid": "4210010", "title": "Diabetic ketoacidosis presenting as neurosurgical emergencies.", "content": "Diabetic ketoacidosis presenting as neurosurgical emergencies. Three cases of ketoacidosis in previously unsuspected diabetics are described. Each was admitted to hospital as a neurosurgical emergency. The recognition of this rare presentation is stressed since prompt treatment of the metabolic disturbance rapidly resolves the neurological abnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210010"} {"pmid": "4210012", "title": "The bladder lymphatics. A study of drug transport.", "content": "The bladder lymphatics. A study of drug transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210012"} {"pmid": "4210013", "title": "Serum beta 2-glycoprotein 1 phenotype frequencies in an English population.", "content": "Serum beta 2-glycoprotein 1 phenotype frequencies in an English population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210013"} {"pmid": "4210014", "title": "Mannose phosphate isomerase: additional variants in primates.", "content": "Mannose phosphate isomerase: additional variants in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210014"} {"pmid": "4210016", "title": "A method for cloning anchorage-dependent cells in agarose.", "content": "A method for cloning anchorage-dependent cells in agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210016"} {"pmid": "4210017", "title": "Plant carbonic anhydrase. Properties and carbon dioxide hydration kinetics.", "content": "Plant carbonic anhydrase. Properties and carbon dioxide hydration kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210017"} {"pmid": "4210018", "title": "Structure of immunoglobulin A. Cysteine-containing peptides of the alpha chain of an immunoglobulin A-1 myeloma protein.", "content": "Structure of immunoglobulin A. Cysteine-containing peptides of the alpha chain of an immunoglobulin A-1 myeloma protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210018"} {"pmid": "4210019", "title": "Potatoes and spina bifida.", "content": "Potatoes and spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210019"} {"pmid": "4210021", "title": "The TSH, FSH and prolactin responses to continuous infusions of TRH and the effects of oestrogen administration in normal males.", "content": "The TSH, FSH and prolactin responses to continuous infusions of TRH and the effects of oestrogen administration in normal males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210021"} {"pmid": "4210022", "title": "Thyroid function in euthyroid subjects with autonomous thyroid nodules.", "content": "Thyroid function in euthyroid subjects with autonomous thyroid nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210022"} {"pmid": "4209997", "title": "Proceedings: 313. Unit activity of the prefrontal cortex and light-lever press reaction.", "content": "Proceedings: 313. Unit activity of the prefrontal cortex and light-lever press reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4209997"} {"pmid": "4210023", "title": "Control of sn-glycerol 3-phosphate oxidation in brown adipose tissue mitochondria by calcium and acyl-CoA.", "content": "Control of sn-glycerol 3-phosphate oxidation in brown adipose tissue mitochondria by calcium and acyl-CoA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210023"} {"pmid": "4210024", "title": "Disc-gel electrophoresis of plus and minus strains and of gymnothecial cultures of Arthroderma tuberculatum.", "content": "Disc-gel electrophoresis of plus and minus strains and of gymnothecial cultures of Arthroderma tuberculatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210024"} {"pmid": "4210025", "title": "Effect of dimethyl sulfoxide on natural resistance to bacterial infections in mice.", "content": "Effect of dimethyl sulfoxide on natural resistance to bacterial infections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210025"} {"pmid": "4210026", "title": "Ultrastructure of Rhodospirillum rubrum after freeze-etching.", "content": "Ultrastructure of Rhodospirillum rubrum after freeze-etching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210026"} {"pmid": "4210033", "title": "Mutagenic activity of the insecticide oxydemetonmethyl in a resistant strain of Drosophila melanogaster.", "content": "Mutagenic activity of the insecticide oxydemetonmethyl in a resistant strain of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210033"} {"pmid": "4210035", "title": "Titration of precipitating antibody in equine infectious anemia.", "content": "Titration of precipitating antibody in equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210035"} {"pmid": "4210036", "title": "Bacillus cereus outgrowth \"early proteins\" and their possible role in control of transcription.", "content": "Bacillus cereus outgrowth \"early proteins\" and their possible role in control of transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210036"} {"pmid": "4210037", "title": "Genetic analysis of rec mutants of Bacillus subtilis. Evidence for at least six linkage groups.", "content": "Genetic analysis of rec mutants of Bacillus subtilis. Evidence for at least six linkage groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210037"} {"pmid": "4210038", "title": "Multi-locus polymorphism and selection in a population of Drosophila melanogaster. I. Linkage disequilibrium on chromosome 3.", "content": "Multi-locus polymorphism and selection in a population of Drosophila melanogaster. I. Linkage disequilibrium on chromosome 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210038"} {"pmid": "4210039", "title": "Ankle sprains in young athletes. Relation of severity and disability.", "content": "Ankle sprains in young athletes. Relation of severity and disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210039"} {"pmid": "4210043", "title": "Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. A morphological and histochemical study of the pars recta during malonate poisoning.", "content": "Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. A morphological and histochemical study of the pars recta during malonate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210043"} {"pmid": "4210042", "title": "Effects of 5-bromodeoxyuridine on rat embryo cell cultures.", "content": "Effects of 5-bromodeoxyuridine on rat embryo cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210042"} {"pmid": "4210041", "title": "Quantitative cytochemical estimation of the effect of pentagastrin (0.005-5 pg-ml) and of plasma gastrin on the guinea-pig fundus in vitro.", "content": "Quantitative cytochemical estimation of the effect of pentagastrin (0.005-5 pg-ml) and of plasma gastrin on the guinea-pig fundus in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210041"} {"pmid": "4210044", "title": "Quantitative changes in mitochondria of guinea pig myocardium following anaesthesia with halothane.", "content": "Quantitative changes in mitochondria of guinea pig myocardium following anaesthesia with halothane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210044"} {"pmid": "4210046", "title": "Urinary acidification and carbonic anhydrase distribution in bladders of Dominican and Colombian toads.", "content": "Urinary acidification and carbonic anhydrase distribution in bladders of Dominican and Colombian toads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210046"} {"pmid": "4210050", "title": "Clinical assessment of glybenclamide (daonil) in diabetes mellitus.", "content": "Clinical assessment of glybenclamide (daonil) in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210050"} {"pmid": "4210053", "title": "Neurofibromatosis with meningioma orbit (a case report).", "content": "Neurofibromatosis with meningioma orbit (a case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210053"} {"pmid": "4210059", "title": "TRH stimulated TSH response in euthyroid healthy subjects and patients with thyroid dysfunction.", "content": "TRH stimulated TSH response in euthyroid healthy subjects and patients with thyroid dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210059"} {"pmid": "4210063", "title": "Biological characterization of a high energy neutron beam for radiation therapy.", "content": "Biological characterization of a high energy neutron beam for radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210063"} {"pmid": "4210064", "title": "Localization error in the radiotherapy of Hodgkin's disease and malignant lymphoma with extended mantle fields.", "content": "Localization error in the radiotherapy of Hodgkin's disease and malignant lymphoma with extended mantle fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210064"} {"pmid": "4210061", "title": "Urine homovanillic acid and tissue dopa oxidase in patients with melanoma.", "content": "Urine homovanillic acid and tissue dopa oxidase in patients with melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210061"} {"pmid": "4210062", "title": "The RBE of neutrons in vivo.", "content": "The RBE of neutrons in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210062"} {"pmid": "4210060", "title": "A comparative study on drug hydroxylation and glucuronidation in liver microsomes of phenobarbital and 3-methylcholanthrene treated rats.", "content": "A comparative study on drug hydroxylation and glucuronidation in liver microsomes of phenobarbital and 3-methylcholanthrene treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210060"} {"pmid": "4210065", "title": "A report on three years' fast neutron therapy from the Medical Research Council's cyclotron at Hammersmith Hospital, London.", "content": "A report on three years' fast neutron therapy from the Medical Research Council's cyclotron at Hammersmith Hospital, London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210065"} {"pmid": "4210066", "title": "An experimental model for chronic communicating hydrocephalus.", "content": "An experimental model for chronic communicating hydrocephalus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210066"} {"pmid": "4210067", "title": "Sequential changes of vascular ultrastructure in experimental cerebral vasospasm. Myonecrosis of subarachnoid arteries.", "content": "Sequential changes of vascular ultrastructure in experimental cerebral vasospasm. Myonecrosis of subarachnoid arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210067"} {"pmid": "4210068", "title": "Extradural ossification following an extradural hematoma. Case report.", "content": "Extradural ossification following an extradural hematoma. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210068"} {"pmid": "4210069", "title": "Effects of operantly conditioning epileptic unit activity on seizure frequencies and electrophysiology of neocortical experimental foci.", "content": "Effects of operantly conditioning epileptic unit activity on seizure frequencies and electrophysiology of neocortical experimental foci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210069"} {"pmid": "4210072", "title": "Recent research on malaria in mammals excluding man.", "content": "Recent research on malaria in mammals excluding man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210072"} {"pmid": "4210073", "title": "New knowledge of toxoplasma and toxoplasmosis.", "content": "New knowledge of toxoplasma and toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210073"} {"pmid": "4210075", "title": "Errors in performance and interpretation of echocardiograms.", "content": "Errors in performance and interpretation of echocardiograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210075"} {"pmid": "4210074", "title": "The influence of ovarian sonication on fetal development in the rat.", "content": "The influence of ovarian sonication on fetal development in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210074"} {"pmid": "4210076", "title": "The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone.", "content": "The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210076"} {"pmid": "4210077", "title": "Isolation of ferritin from human mammary and pancreatic carcinomas by means of antibody immunoadsorbents.", "content": "Isolation of ferritin from human mammary and pancreatic carcinomas by means of antibody immunoadsorbents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210077"} {"pmid": "4210078", "title": "Effect of vitamin B-12 deprivation on the rates of synthesis and degradation of rat liver fatty acid synthetase.", "content": "Effect of vitamin B-12 deprivation on the rates of synthesis and degradation of rat liver fatty acid synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210078"} {"pmid": "4210079", "title": "Chemical and physical properties of a carotenoprotein from Rhodospirillum rubrum.", "content": "Chemical and physical properties of a carotenoprotein from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210079"} {"pmid": "4210080", "title": "Studies on Fd-fragments of human immunoglobulins. II. The preparation and characterization of peptic (Fab')2-fragments and an Fd'-fragment of IgA-myeloma proteins.", "content": "Studies on Fd-fragments of human immunoglobulins. II. The preparation and characterization of peptic (Fab')2-fragments and an Fd'-fragment of IgA-myeloma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210080"} {"pmid": "4210081", "title": "The influence of magnesium on the chlorophyll fluorescence yield of isolated chloroplasts.", "content": "The influence of magnesium on the chlorophyll fluorescence yield of isolated chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210081"} {"pmid": "4210083", "title": "Studies of serum from patients with breast cancer.", "content": "Studies of serum from patients with breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210083"} {"pmid": "4210058", "title": "Comparative scrapie activity of brain material and cerebrospinal fluid from scrapie-affected rats.", "content": "Comparative scrapie activity of brain material and cerebrospinal fluid from scrapie-affected rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210058"} {"pmid": "4210084", "title": "Studies on dextranase. II. New exo-dextranase from Brevibacterium fuscum var. Dextranlyticum.", "content": "Studies on dextranase. II. New exo-dextranase from Brevibacterium fuscum var. Dextranlyticum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210084"} {"pmid": "4210085", "title": "The sulfhydryl groups of porcine pancreatic alpha-amylase: unmasking, reactivity and function.", "content": "The sulfhydryl groups of porcine pancreatic alpha-amylase: unmasking, reactivity and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210085"} {"pmid": "4210086", "title": "Activation energy of glucuronide biosynthesis.", "content": "Activation energy of glucuronide biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210086"} {"pmid": "4210087", "title": "DNA-dependent poly (G) synthesizing activities in DNA-dependent RNA polymerase fractions from cauliflower inflorescence.", "content": "DNA-dependent poly (G) synthesizing activities in DNA-dependent RNA polymerase fractions from cauliflower inflorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210087"} {"pmid": "4210089", "title": "Single-dose oral therapy for uncomplicated gonorrhea: comparison of amoxicillin and ampicillin given with and without probenecid.", "content": "Single-dose oral therapy for uncomplicated gonorrhea: comparison of amoxicillin and ampicillin given with and without probenecid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210089"} {"pmid": "4210090", "title": "Therapy of uncomplicated gonococcal urethritis in the male with a single dose of amoxicillin.", "content": "Therapy of uncomplicated gonococcal urethritis in the male with a single dose of amoxicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210090"} {"pmid": "4210092", "title": "Treatment of uncomplicated gonorrhea with amoxicillin.", "content": "Treatment of uncomplicated gonorrhea with amoxicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210092"} {"pmid": "4210094", "title": "Experimental Pseudomonas granuloma in the skin of guinea pigs.", "content": "Experimental Pseudomonas granuloma in the skin of guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210094"} {"pmid": "4210091", "title": "Treatment of uncomplicated gonorrhea in women with a single dose of amoxicillin.", "content": "Treatment of uncomplicated gonorrhea in women with a single dose of amoxicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210091"} {"pmid": "4210097", "title": "The trypanosomes of anura.", "content": "The trypanosomes of anura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210097"} {"pmid": "4210096", "title": "Comparative study of the function of polytene chromosomes in laboratory stocks of Drosophila melanogaster and the l(3)tl mutant (lethal tumorous larvae). I. Analysis of puffing patterns in autosomes of the laboratory stock Batumi-L.", "content": "Comparative study of the function of polytene chromosomes in laboratory stocks of Drosophila melanogaster and the l(3)tl mutant (lethal tumorous larvae). I. Analysis of puffing patterns in autosomes of the laboratory stock Batumi-L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210096"} {"pmid": "4210098", "title": "Diagnostic ultrasound in radiation treatment planning.", "content": "Diagnostic ultrasound in radiation treatment planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210098"} {"pmid": "4210095", "title": "Changed pattern of transcription and replication in polytene chromosomes of Drosophila melanogaster resulting from eu-heterochromatin rearrangement.", "content": "Changed pattern of transcription and replication in polytene chromosomes of Drosophila melanogaster resulting from eu-heterochromatin rearrangement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210095"} {"pmid": "4210100", "title": "Prednisolone-induced mucormycosis in rhesus monkeys.", "content": "Prednisolone-induced mucormycosis in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210100"} {"pmid": "4210099", "title": "Metabolism of carbaryl by selected human tissues using an organ-maintenance technique.", "content": "Metabolism of carbaryl by selected human tissues using an organ-maintenance technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210099"} {"pmid": "4210102", "title": "Lymphocyte stimulation in Candida albicans infections.", "content": "Lymphocyte stimulation in Candida albicans infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210102"} {"pmid": "4210101", "title": "Mycologic, serologic and histologic findings in bovine abortion associated with Allescheria boydii.", "content": "Mycologic, serologic and histologic findings in bovine abortion associated with Allescheria boydii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210101"} {"pmid": "4210104", "title": "Growth of measles virus in nervous tissues. II. Neurotropic properties of a SSPE virus in hamsters.", "content": "Growth of measles virus in nervous tissues. II. Neurotropic properties of a SSPE virus in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210104"} {"pmid": "4210103", "title": "Effect of estrogen on serum total and free thyroxine and triiodothyronine in a thyroxine-binding globulin deficient family.", "content": "Effect of estrogen on serum total and free thyroxine and triiodothyronine in a thyroxine-binding globulin deficient family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210103"} {"pmid": "4210105", "title": "Normal values of the serum protein fractions in cynomolgus monkeys used as experimental animals.", "content": "Normal values of the serum protein fractions in cynomolgus monkeys used as experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210105"} {"pmid": "4210106", "title": "Recent developments in magnesium research in pediatrics.", "content": "Recent developments in magnesium research in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210106"} {"pmid": "4210107", "title": "Glutathione reductase in the sea urchin egg. II. Cleavage-associating fluctuation of the activity and its possible regulatory mechanism.", "content": "Glutathione reductase in the sea urchin egg. II. Cleavage-associating fluctuation of the activity and its possible regulatory mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210107"} {"pmid": "4210111", "title": "Management of urinary tract infection in acute paraplegic patients with special reference to the paper strip screening test for infection.", "content": "Management of urinary tract infection in acute paraplegic patients with special reference to the paper strip screening test for infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210111"} {"pmid": "4210109", "title": "Evidence of homology between the beta-chain of human haptoglobin and the chymotrypsin family of serine proteases.", "content": "Evidence of homology between the beta-chain of human haptoglobin and the chymotrypsin family of serine proteases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210109"} {"pmid": "4210113", "title": "The incidence of ABO and Rh blood groups in the Bellary area--a random survey.", "content": "The incidence of ABO and Rh blood groups in the Bellary area--a random survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210113"} {"pmid": "4210114", "title": "Haemorrhagic complications after penicillin therapy.", "content": "Haemorrhagic complications after penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210114"} {"pmid": "4210115", "title": "The patterns of infection in cystic fibrosis.", "content": "The patterns of infection in cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210115"} {"pmid": "4210116", "title": "Faulty proteins: altered gene products in senescent cells and organisms.", "content": "Faulty proteins: altered gene products in senescent cells and organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210116"} {"pmid": "4210117", "title": "Circulatory effects of intravenously administered rolitetracycline and other tetracyclines in animal experiments.", "content": "Circulatory effects of intravenously administered rolitetracycline and other tetracyclines in animal experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210117"} {"pmid": "4210119", "title": "Different immunofluorescent titres of Candida albicans blastospores and pseudohyphae.", "content": "Different immunofluorescent titres of Candida albicans blastospores and pseudohyphae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210119"} {"pmid": "4210126", "title": "Reflex (sensory precipitation) epilepsy (review and case report).", "content": "Reflex (sensory precipitation) epilepsy (review and case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210126"} {"pmid": "4210130", "title": "Agar ingestion and serum bilirubin values in newborn infants.", "content": "Agar ingestion and serum bilirubin values in newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210130"} {"pmid": "4210124", "title": "Genetic improvement of plant protein.", "content": "Genetic improvement of plant protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210124"} {"pmid": "4210128", "title": "Comparative in vitro activity of kanendomycin, kanamycin, gentamicin and streptomycin against 100 consecutive cultures of tubercle bacilli recovered from patients.", "content": "Comparative in vitro activity of kanendomycin, kanamycin, gentamicin and streptomycin against 100 consecutive cultures of tubercle bacilli recovered from patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210128"} {"pmid": "4210129", "title": "National health insurance proposals: which one will it be?", "content": "National health insurance proposals: which one will it be?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210129"} {"pmid": "4210125", "title": "Accumulation of dietary polychlorinated biphenyls (Aroclor 1254) by rainbow trout (Salmo gairdneri).", "content": "Accumulation of dietary polychlorinated biphenyls (Aroclor 1254) by rainbow trout (Salmo gairdneri).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210125"} {"pmid": "4210127", "title": "Immunológical studies in lymphoma patients IX. Detection of antimycotic antibodies.", "content": "Immunológical studies in lymphoma patients IX. Detection of antimycotic antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210127"} {"pmid": "4210145", "title": "A method to demonstrate the specificity and sensitivity of fluorescent antibody by immunoelectrophoresis and immunodiffusion using ultraviolet light photography.", "content": "A method to demonstrate the specificity and sensitivity of fluorescent antibody by immunoelectrophoresis and immunodiffusion using ultraviolet light photography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210145"} {"pmid": "4210146", "title": "Electroimmunodiffusion on cellulose acetate: a rapid method for analysis of bovine lactoferrin in chromatography effluents.", "content": "Electroimmunodiffusion on cellulose acetate: a rapid method for analysis of bovine lactoferrin in chromatography effluents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210146"} {"pmid": "4210148", "title": "Uptake of glibornuride by microdissected pancreatic islets.", "content": "Uptake of glibornuride by microdissected pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210148"} {"pmid": "4210147", "title": "Isolation and purification of an organ-specific autoantigen from rabbit seminal plasma.", "content": "Isolation and purification of an organ-specific autoantigen from rabbit seminal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210147"} {"pmid": "4210149", "title": "Letter: Effects of formaldehyde and glutaraldehyde fixation on the monoamine oxidase activity in isolated rat liver mitochondria.", "content": "Letter: Effects of formaldehyde and glutaraldehyde fixation on the monoamine oxidase activity in isolated rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210149"} {"pmid": "4210151", "title": "Transcription of mammalian satellite DNAs by homologous DNA-dependent RNA polymerases.", "content": "Transcription of mammalian satellite DNAs by homologous DNA-dependent RNA polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210151"} {"pmid": "4210150", "title": "Coatings as barriers to prevent polychlorinated biphenyl contamination of silage.", "content": "Coatings as barriers to prevent polychlorinated biphenyl contamination of silage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210150"} {"pmid": "4210153", "title": "Effect of photooxidative conditions on levels of superoxide dismutase in Anacystis nidulans.", "content": "Effect of photooxidative conditions on levels of superoxide dismutase in Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210153"} {"pmid": "4210155", "title": "Analysis of herbicides.", "content": "Analysis of herbicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210155"} {"pmid": "4210156", "title": "Synthesis of 3'-amido-3'-deoxyadenosine 3',5'-cyclophosphate.", "content": "Synthesis of 3'-amido-3'-deoxyadenosine 3',5'-cyclophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210156"} {"pmid": "4210158", "title": "Exchange within heterozygous inversions in Drosophila melanogaster.", "content": "Exchange within heterozygous inversions in Drosophila melanogaster. The exchange behavior of non-attached, whole arm, X chromosome inversions was reexamined using nondisjunction in XXY females as an indirect measure of the frequency of nonexchange tetrads. Crossing over is quite normal in these inversion heterozygotes and is independent of the arrangement of the basal heterochromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210158"} {"pmid": "4210157", "title": "Specificity of purified hemagglutinin (lectin) from Lotus tetragonolobus.", "content": "Specificity of purified hemagglutinin (lectin) from Lotus tetragonolobus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210157"} {"pmid": "4210159", "title": "Complementation analysis of late lethal mutants of Drosophila melanogaster.", "content": "Complementation analysis of late lethal mutants of Drosophila melanogaster. Late larval and pupal lethal mutants of Drosophila define those gene functions which are essential for the development of pupae (metamorphosis) but not for embryonic or larval development. In a previous report the isolation of a large number of such mutants was outlined, and a description of the imaginal disc defects in those mutants was described. This report concerns genetic analysis of those mutants. 3746 different pairwise combinations of mutants have been tested for complementation. Only 10 pairs fail to complement. In all of the cases tested, the lethal mutation in each member of a non-complementing pair has a similar map location. In addition to the non-complementing pairs one group of seven partially-complementing mutants has been identified. Comparisons of the imaginal disc defects within the non-complementing pairs and the lethal hybrids formed by the respective pairs were made to test for uniformity of phenotype. No significant qualitative differences were detected between any non-complementing pairs or their respective hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210159"} {"pmid": "4210162", "title": "Hypertension detection by dentists.", "content": "Hypertension detection by dentists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210162"} {"pmid": "4210161", "title": "Marginal leakage of various restorative materials.", "content": "Marginal leakage of various restorative materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210161"} {"pmid": "4210154", "title": "Effects of 60Co gamma irradiation on aflatoxin B1 and B2 production by Aspergillus flavus.", "content": "Effects of 60Co gamma irradiation on aflatoxin B1 and B2 production by Aspergillus flavus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210154"} {"pmid": "4210166", "title": "Seizures in patients over the age of 40: a general hospital study.", "content": "Seizures in patients over the age of 40: a general hospital study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210166"} {"pmid": "4210169", "title": "Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain.", "content": "Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210169"} {"pmid": "4210168", "title": "Electrocardiogram as a guide to potassium replacement in diabetic ketoacidosis.", "content": "Electrocardiogram as a guide to potassium replacement in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210168"} {"pmid": "4210170", "title": "Cecal diverticulum strangulated in femoral hernia.", "content": "Cecal diverticulum strangulated in femoral hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210170"} {"pmid": "4210171", "title": "Amniotic fluid tests for fetal maturity.", "content": "Amniotic fluid tests for fetal maturity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210171"} {"pmid": "4210172", "title": "Development of enteric parasites in parenterally fed rats.", "content": "Development of enteric parasites in parenterally fed rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210172"} {"pmid": "4210173", "title": "Stimulation of prolactin and growth hormone release by TRH infused into a hypophysial portal vessel.", "content": "Stimulation of prolactin and growth hormone release by TRH infused into a hypophysial portal vessel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210173"} {"pmid": "4210160", "title": "Tay-Sachs' disease and Fabry's disease: clinical and chemical diagnosis of two metabolic eye diseases.", "content": "Tay-Sachs' disease and Fabry's disease: clinical and chemical diagnosis of two metabolic eye diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210160"} {"pmid": "4210174", "title": "Relationship of ambient temperature to serum prolactin in heifers.", "content": "Relationship of ambient temperature to serum prolactin in heifers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210174"} {"pmid": "4210175", "title": "Intravenous hyperalimentation.", "content": "Intravenous hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210175"} {"pmid": "4210179", "title": "The diagnosis of myocardial infarction in the Wolff-Parkinson-White syndrome.", "content": "The diagnosis of myocardial infarction in the Wolff-Parkinson-White syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210179"} {"pmid": "4210180", "title": "The social context of coronary artery surgery.", "content": "The social context of coronary artery surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210180"} {"pmid": "4210181", "title": "The effects of extraoral low-pull traction to the mandibular dentition of Macaca mulatta.", "content": "The effects of extraoral low-pull traction to the mandibular dentition of Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210181"} {"pmid": "4210182", "title": "Neuromuscular and skeletal adaptations to altered function in the orofacial region.", "content": "Neuromuscular and skeletal adaptations to altered function in the orofacial region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210182"} {"pmid": "4210183", "title": "Gastric clearance of serum albumin in normal man and in certain gastroduodenal disorders.", "content": "Gastric clearance of serum albumin in normal man and in certain gastroduodenal disorders. Serum albumin gastric loss was estimated from the measurement of non-dialysable radioactivity of the gastric juice after intravenous injection of radioiodinated serum albumin (RISA). Immunochemical quantitation of serum albumin was performed in some of the samples. In the control group, the mean gastric clearance of albumin was 1.71 ml per hour with a range of 0.41 to 4.41 ml per hour. This represented a gastric loss of 1.9 gram of albumin per day and 11% of the daily degradation of albumin. There was no significant change in the gastric albumin loss after stimulating the gastric secretion. No significant difference in the gastric albumin leakage was found between normal subjects and patients with gastric or duodenal ulcer. IN PERNICIOUS ANAEMIA ALBUMIN LOSS INTO THE STOMACH WAS GREATER (MEAN: 3.72 ml per hour; SD 1.52 ml) than in the normal group and accounted for the greater albumin fractional catabolic rate. This fact had never been proved before. In both patients with giant rugae of the gastric mucosa the gastric clearance of serum albumin was also increased. It is concluded first that albumin is not secreted by the chief and parietal cells of the mucosa and probably passes through the gastric wall between the cells of the mucosa, perhaps during the exfoliation of the surface epithelial cells, and secondly that the stomach is one of the sites of serum albumin breakdown, a fact that supports the view that the gastrointestinal tract plays a major role in the catabolism of serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210183"} {"pmid": "4210184", "title": "Dietary fat and coronary heart disease: A review. I. Diet in the prevention of coronary heart disease and some pathogenetic aspects.", "content": "Dietary fat and coronary heart disease: A review. I. Diet in the prevention of coronary heart disease and some pathogenetic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210184"} {"pmid": "4210185", "title": "Resistance of Neisseria gonorrhoeae to penicillin in 199 gonococcal infections in women and the response of those infections to penicillin treatment.", "content": "Resistance of Neisseria gonorrhoeae to penicillin in 199 gonococcal infections in women and the response of those infections to penicillin treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210185"} {"pmid": "4210188", "title": "Physical changes in the bone tissue of the skull due to head injury.", "content": "Physical changes in the bone tissue of the skull due to head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210188"} {"pmid": "4210192", "title": "Kinetic behavior of enzymes in artificial membranes. Inhibition and reversibility effects.", "content": "Kinetic behavior of enzymes in artificial membranes. Inhibition and reversibility effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210192"} {"pmid": "4210193", "title": "The role of insulin and growth hormone in fetal growth.", "content": "The role of insulin and growth hormone in fetal growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210193"} {"pmid": "4210194", "title": "Letter: Comparison of pain cry in neonates with and without feeding tube.", "content": "Letter: Comparison of pain cry in neonates with and without feeding tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210194"} {"pmid": "4210198", "title": "Effect of caffeine on crossing-over in Drosophila melanogaster.", "content": "Effect of caffeine on crossing-over in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210198"} {"pmid": "4210199", "title": "Report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry.", "content": "Report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210199"} {"pmid": "4210200", "title": "Antigenicity of normal and tumoral glycoproteins correlated with their action on serum glycoproteins.", "content": "Antigenicity of normal and tumoral glycoproteins correlated with their action on serum glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210200"} {"pmid": "4210201", "title": "The influence of radiation on blood vessels and circulation. Chapter VII. Functional response of heart and major vessels.", "content": "The influence of radiation on blood vessels and circulation. Chapter VII. Functional response of heart and major vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210201"} {"pmid": "4210203", "title": "Special needs of long-term patients.", "content": "Special needs of long-term patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210203"} {"pmid": "4210202", "title": "Actions of lithium ions and insulin on glucose utilization, glycogen synthesis and glycogen synthase in the isolated rat diaphragm.", "content": "Actions of lithium ions and insulin on glucose utilization, glycogen synthesis and glycogen synthase in the isolated rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210202"} {"pmid": "4210196", "title": "Stepping movements evoked by repetitive dorsal root stimulation in a mesencephalic cat.", "content": "Stepping movements evoked by repetitive dorsal root stimulation in a mesencephalic cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210196"} {"pmid": "4210197", "title": "Cortico-mamillary tracts of the brain.", "content": "Cortico-mamillary tracts of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210197"} {"pmid": "4210195", "title": "Dominant afferentation and quantitative reorganization of auditory and visual analyzers in the brainstem of carnivores and primates, including man.", "content": "Dominant afferentation and quantitative reorganization of auditory and visual analyzers in the brainstem of carnivores and primates, including man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210195"} {"pmid": "4210209", "title": "Cleavage of actin by thrombin.", "content": "Cleavage of actin by thrombin. Under certain conditions actin can be split by thrombin. Actin prepared in the presence of excess Ca(++) was found to be resistant to thrombin. However, if actin was purified without added Ca(++), both G- and F- actin underwent thrombic digestion, although a considerable proportion of actin molecules remained intact. Similar results were obtained with actin (in 50% sucrose) devoid of nucleotide and divalent cations but retaining its native characteristic. The removal of tightly bound Ca(++) from actin by EDTA accelerated the thrombic splitting and made the complete fragmentation of G-actin possible. Thrombin first cleaves actin into two pieces and subsequently one of them, fragment K (molecular weight 37,000 on sodium dodecyl sulfate-polyacrylamide gel), splits further, resulting in fragments L (molecular weight 27,000) and M (molecular weight about 10,000).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210209"} {"pmid": "4210210", "title": "Actin antibody: the specific visualization of actin filaments in non-muscle cells.", "content": "Actin antibody: the specific visualization of actin filaments in non-muscle cells. Actin purified from mouse fibroblasts by sodium dodecyl sulfate gel electrophoresis was used as antigen to obtain an antibody in rabbits. The elicited antibody was shown to be specific for actin as judged by immunodiffusion and complement fixation against partially purified mouse fibroblast actin and highly purified chicken muscle actin. The antibody was used in indirect immunofluorescence to demonstrate by fluorescence light microscopy the distribution and pattern of actin-containing filaments in a variety of cell types. Actin filaments were shown to span the cell length or to concentrate in \"focal points\" in patterns characteristic for each individual cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210210"} {"pmid": "4210213", "title": "Radiology of small intestinal bleeding.", "content": "Radiology of small intestinal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210213"} {"pmid": "4210211", "title": "Homology between bakers' yeast cytochrome b2 and liver microsomal cytochrome b5.", "content": "Homology between bakers' yeast cytochrome b2 and liver microsomal cytochrome b5. The amino-acid sequence of the hemebinding region of bakers' yeast cytochrome b(2) [L-(+)-lactate dehydrogenase, EC 1.1.2.3] has been determined. It shows a strong similarity with the sequence of microsomal cytochrome b(5), and appears to be compatible with the same kind of peptide-chain folding, in agreement with data obtained previously by various physiochemical methods. The comparison shows that the fifth and sixth heme ligands must be histidine residues, thus substantiating previous conclusions drawn in particular from photooxidation experiments and nuclear magnetic resonance studies. The data reported in this paper suggest a common origin for the two proteins. Implications for their biochemical evolution are presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210211"} {"pmid": "4210212", "title": "Functional differences in the multiple hemocyanins of the horseshoe crab, Limulus polyphemus L.", "content": "Functional differences in the multiple hemocyanins of the horseshoe crab, Limulus polyphemus L. Hemocyanin in the hemolymph of the horseshoe crab, Limulus polyphemus L., is a high-molecular-weight copper protein which binds oxygen cooperatively and shows a higher oxygen affinity at pH 7 than at pH 9. Treatment with EDTA (ethylenediaminetetra-acetate) disaggregates the hemocyanin molecules and abolishes both the reverse Bohr effect and cooperative oxygen binding. Chloride ions interact with the EDTA-treated material and, in the presence of saturating amounts of NaCl, a reverse Bohr effect is restored, but cooperativity is not. The EDTA-treated hemocyanin contains at least five electrophoretically distinct hemocyanins. These hemocyanins have similar molecular weights (about 66,000) but are functionally dissimilar. They have different oxygen affinities and different responses to chloride ions. The effect of chloride ions on unfractionated hemocyanin is due to pH-dependent chloride interactions with only two of the five hemocyanin components. The functional differences between the hemocyanin components may provide Limulus with a valuable respiratory flexibility in its interaction with the environment. The kinetics of oxygen combination and dissociation for the various hemocyanin preparations show that variations in the rate of oxygen dissociation are primarily responsible for the observed differences in oxygen affinity. The rate of oxygen dissociation varies 20-fold under conditions where the apparent rate of oxygen combination shows less than a 2-fold variation. Cooperative interactions in the untreated hemocyanin are most obvious in the \"off\" reaction, which increases in rate as successive oxygen molecules are released.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210212"} {"pmid": "4210214", "title": "Myonecrosis in chronic experimental vasospasm.", "content": "Myonecrosis in chronic experimental vasospasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210214"} {"pmid": "4210215", "title": "The effects of testosterone on the sexual skin and genitalia of the male talapoin monkey.", "content": "The effects of testosterone on the sexual skin and genitalia of the male talapoin monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210215"} {"pmid": "4210216", "title": "Degradation of immunoglobulins by secretions of human reproductive tracts.", "content": "Degradation of immunoglobulins by secretions of human reproductive tracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210216"} {"pmid": "4210217", "title": "Proceedings: Electrical responses of the limbic regions to exogenous testosterone and stimulation of the genital regions.", "content": "Proceedings: Electrical responses of the limbic regions to exogenous testosterone and stimulation of the genital regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210217"} {"pmid": "4210221", "title": "The first two electron linear accelerators in South Africa.", "content": "The first two electron linear accelerators in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210221"} {"pmid": "4210222", "title": "Proplast in cavity obliteration and soft tissue augmentation.", "content": "Proplast in cavity obliteration and soft tissue augmentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210222"} {"pmid": "4210223", "title": "Studies on physiology and biochemistry of mammalian epididymis: Histology, enzyme and electrolyte composition of epididymis--a comparative study.", "content": "Studies on physiology and biochemistry of mammalian epididymis: Histology, enzyme and electrolyte composition of epididymis--a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210223"} {"pmid": "4210224", "title": "Influence of biological criteria on the magnitude of damage induced by gamma-rays and gamma-irradiated medium.", "content": "Influence of biological criteria on the magnitude of damage induced by gamma-rays and gamma-irradiated medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210224"} {"pmid": "4210225", "title": "Genetic effects induced in Drosophila melanogaster cultured on irradiated glucose medium.", "content": "Genetic effects induced in Drosophila melanogaster cultured on irradiated glucose medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210225"} {"pmid": "4210226", "title": "Induction of mutations by thioridazine hydrochloride, an active ingredient of Mellaril.", "content": "Induction of mutations by thioridazine hydrochloride, an active ingredient of Mellaril.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210226"} {"pmid": "4210227", "title": "Fermentative production of alpha-amylase by Aspergillus flavus.", "content": "Fermentative production of alpha-amylase by Aspergillus flavus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210227"} {"pmid": "4210228", "title": "Detection of preformed enterotoxins of staphylococci in dairy products employing serological method.", "content": "Detection of preformed enterotoxins of staphylococci in dairy products employing serological method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210228"} {"pmid": "4210220", "title": "Etiology of tuberculosis cutis in Jakarta.", "content": "Etiology of tuberculosis cutis in Jakarta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210220"} {"pmid": "4210218", "title": "Need for improved plant proteins in world nutrition.", "content": "Need for improved plant proteins in world nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210218"} {"pmid": "4210229", "title": "Influence of external factors on extracellular amino acid accumulation by Bacillus megaterium strain C II 19.", "content": "Influence of external factors on extracellular amino acid accumulation by Bacillus megaterium strain C II 19.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210229"} {"pmid": "4210230", "title": "Australia antigen in chronic liver diseases.", "content": "Australia antigen in chronic liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210230"} {"pmid": "4210243", "title": "Gonadotropins and their antibodies.", "content": "Gonadotropins and their antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210243"} {"pmid": "4210245", "title": "Viruses and the etiology of diabetes.", "content": "Viruses and the etiology of diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210245"} {"pmid": "4210237", "title": "Fetal electrocardiographic evaluation of Rh-immunized pregnancies. Preliminary results by a new averaging technique.", "content": "Fetal electrocardiographic evaluation of Rh-immunized pregnancies. Preliminary results by a new averaging technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210237"} {"pmid": "4210235", "title": "Preliminary results of Rh-prophylaxis during pregnancy.", "content": "Preliminary results of Rh-prophylaxis during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210235"} {"pmid": "4210246", "title": "Morphologic changes of uterine wall following intra-amniotic injection of hypertonic saline in the rhesus monkey.", "content": "Morphologic changes of uterine wall following intra-amniotic injection of hypertonic saline in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210246"} {"pmid": "4210247", "title": "Firing patterns of hypothalamic supraoptic neurons during water deprivation in monkeys.", "content": "Firing patterns of hypothalamic supraoptic neurons during water deprivation in monkeys. Water deprivation in monkeys caused an acceleration of action potential firing of supraoptic neurons, but not of neurons located 2 to 3 millimeters above the hypothalamic supraoptic nucleus. Whereas in the normally hydrated animal only 12 percent of the neuroendocrine cells discharged periodically, the proportion of these periodic bursters increased markedly with increasing plasma osmolarity. This finding suggests that such periodically firing supraoptic neurons are those engaged in active neurohypophyseal hormone secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210247"} {"pmid": "4210248", "title": "Intrathoracic meningocele associated with multiple neurofibromatosis: a rare cause of mediastinal tumour.", "content": "Intrathoracic meningocele associated with multiple neurofibromatosis: a rare cause of mediastinal tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210248"} {"pmid": "4210234", "title": "Prevention of Rh immunization in Germany.", "content": "Prevention of Rh immunization in Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210234"} {"pmid": "4210249", "title": "Irreversible binding of ethynyl-estradiol metabolites to protein and nucleic acids as catalyzed by rat liver microsomes and mushroom tyrosinase.", "content": "Irreversible binding of ethynyl-estradiol metabolites to protein and nucleic acids as catalyzed by rat liver microsomes and mushroom tyrosinase. It is known that most carcinogenic chemicals can be bound irreversibly to proteins or nucleic acids. A study is presented that explored the irreversible binding of 17alpha-ethinyl estradiol to proteins and nucleic acids by the catalytic action of rat liver microsomes and muschroom tyrosinase. The microsomal binding reaction was inhibited by glutathione and cysteine and its derivatives though it was not affected by lysine and amines. Binding reactivity in the tyrosinase system was inhibited by glutathione, cysteine and its derivates, lysine, and amines. Polylysine did not bind the metabolite of ethinyl estradiol, which suggests the NH2 groups do not bind to the intermediate in the microsomal reaction. However, polylysine did bind irreversibly with esthinyl estradiol metabolites in tyrosinase catalysis. The nonenzymatic reaction of 17beta-hydroxy-4,10(1)-estradiene-2,3-dione with cysteine, lysine, and lysine derivates was found to support the thesis that estrogen o-quinones are the intermediates involved in the protein binding of estrogens in tyrosinase catalysis. An irreversible binding of ethinyl estradiol to DNA and RNA occurred with tyrosinase but not with rat liver microsomes. It was concluded that the results of rat liver microsome catalysis make it unlikely that estrogens are chemical carcinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210249"} {"pmid": "4210252", "title": "Trace analysis of organic compounds.", "content": "Trace analysis of organic compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210252"} {"pmid": "4210253", "title": "The sulfonamide-aminosulfone rearrangement: a rearrangement induced anionically, cationically, and thermally.", "content": "The sulfonamide-aminosulfone rearrangement: a rearrangement induced anionically, cationically, and thermally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210253"} {"pmid": "4210254", "title": "The pigments of reddish hair and feathers.", "content": "The pigments of reddish hair and feathers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210254"} {"pmid": "4210256", "title": "The continuing problem of sepsis-following enzymatic debridement of burns.", "content": "The continuing problem of sepsis-following enzymatic debridement of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210256"} {"pmid": "4210257", "title": "Stroke: early portents of functional recovery in Black patients.", "content": "Stroke: early portents of functional recovery in Black patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210257"} {"pmid": "4210265", "title": "Mass transfer of Co2 across membranes: facilitation in the presence of bicarbonate ion and the enzyme carbonic anhydrase.", "content": "Mass transfer of Co2 across membranes: facilitation in the presence of bicarbonate ion and the enzyme carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210265"} {"pmid": "4210266", "title": "An unusual tumour of the neck and superior mediastinum.", "content": "An unusual tumour of the neck and superior mediastinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210266"} {"pmid": "4210270", "title": "Single radial diffusion using catalase antibody as screening method of hypocatalasemia.", "content": "Single radial diffusion using catalase antibody as screening method of hypocatalasemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210270"} {"pmid": "4210271", "title": "The effects of protein calorie malnutrition on immune competence of the surgical patient.", "content": "The effects of protein calorie malnutrition on immune competence of the surgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210271"} {"pmid": "4210272", "title": "Evaluation of mitochondrial function in the ischemic rat liver.", "content": "Evaluation of mitochondrial function in the ischemic rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210272"} {"pmid": "4210273", "title": "Epithelial cell phagocytosis of Listeria monocytogenes in the conjunctiva.", "content": "Epithelial cell phagocytosis of Listeria monocytogenes in the conjunctiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210273"} {"pmid": "4210274", "title": "Primary reconstruction of depressed frontal skull fractures including those involving the sinus, orbit, and cribriform plate.", "content": "Primary reconstruction of depressed frontal skull fractures including those involving the sinus, orbit, and cribriform plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210274"} {"pmid": "4210275", "title": "Epilepsy after monmissile depressed skull fracture.", "content": "Epilepsy after monmissile depressed skull fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210275"} {"pmid": "4210279", "title": "The secretory immunologic system of fowl. IV. Serum and salivary immunoglobulins in normal, agammaglobulinemic and dysgammaglobulinemic chickens.", "content": "The secretory immunologic system of fowl. IV. Serum and salivary immunoglobulins in normal, agammaglobulinemic and dysgammaglobulinemic chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210279"} {"pmid": "4210278", "title": "Animal model: Oxygen toxicity in nonhuman primates.", "content": "Animal model: Oxygen toxicity in nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210278"} {"pmid": "4210277", "title": "Liver cell differentiation in a chemically defined medium. Morphologic and enzymatic comparisons of in utero rat liver and liver rudiment grown in organ culture.", "content": "Liver cell differentiation in a chemically defined medium. Morphologic and enzymatic comparisons of in utero rat liver and liver rudiment grown in organ culture. The liver diverticulum of the 11-day rat embryo has been grown in a chemically defined medium. Cytodifferentiation and enzymatic activities in the organ culture have been compared with those in the embryonic liver developing in vivo. In the absence of hormone and tissue extracts the liver diverticulum grew and differentiated extensively in the synthetic medium. The appearance and development of cytoplasmic organelles (rough and smooth endoplasmic reticulum, Golgi complex and glycogen particles) and enzymatic activity (glycogen synthetase) in both the embryonic liver and the comparable organ-cultured liver diverticulum were parallel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210277"} {"pmid": "4210276", "title": "Pyelonephritis. 18. Effect of treatment on the pathology of enterococcal pyelonephritis in the rat.", "content": "Pyelonephritis. 18. Effect of treatment on the pathology of enterococcal pyelonephritis in the rat. The effect of antimicrobial therapy on the histopathologic progression of experimental hematogenous pyelonephritis induced in rats by Streptococcus faecalis was studied. Treatment sufficient to render the renal parenchyma sterile strikingly decreased the incidence and severity of calyceal lesions, delayed the progression of papillary lesions but had little effect on the severity of cortical interstitial and tubular alterations. L-forms could not be demonstrated to participate in the pathogenesis of these lesions. Kanamycin had an independent nephrotoxic effect which complicated interpretation of the effect of therapy in animals receiving this agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210276"} {"pmid": "4210280", "title": "Precipitation of serum and tissue proteins by phytohaemagglutinin (PHA) in breast cancer patients.", "content": "Precipitation of serum and tissue proteins by phytohaemagglutinin (PHA) in breast cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210280"} {"pmid": "4210282", "title": "Reciprocal induction of cell division by cells of complementary mating types in Tetrahymena.", "content": "Reciprocal induction of cell division by cells of complementary mating types in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210282"} {"pmid": "4210281", "title": "Sexual dimorphism in the secondary immune response of the Syrian hamster.", "content": "Sexual dimorphism in the secondary immune response of the Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210281"} {"pmid": "4210283", "title": "The rate of uptake of 3H-actinomycin during the cell cycle of Tetrahymena.", "content": "The rate of uptake of 3H-actinomycin during the cell cycle of Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210283"} {"pmid": "4210284", "title": "Rough membranes in Schizosaccharomyces pombe protoplasts.", "content": "Rough membranes in Schizosaccharomyces pombe protoplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210284"} {"pmid": "4210285", "title": "Unit discharges in the mediodorsal nucleus of the squirrel monkey evoked by electrical stimulation of the olfactory bulb.", "content": "Unit discharges in the mediodorsal nucleus of the squirrel monkey evoked by electrical stimulation of the olfactory bulb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210285"} {"pmid": "4210286", "title": "Electroencephalographic changes induced by cerebellar stimulation in freely moving primates.", "content": "Electroencephalographic changes induced by cerebellar stimulation in freely moving primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210286"} {"pmid": "4210287", "title": "Cortical cell discharge patterns in anticipation of a trained movement.", "content": "Cortical cell discharge patterns in anticipation of a trained movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210287"} {"pmid": "4210289", "title": "Changes in complement activity, serum proteins, and prothrombin time in guinea pigs fed rubratoxin alone or in combination with aflatoxin.", "content": "Changes in complement activity, serum proteins, and prothrombin time in guinea pigs fed rubratoxin alone or in combination with aflatoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210289"} {"pmid": "4210290", "title": "Pathogenesis of Trypanosoma equiperdum in deer mice (Peromyscus maniculatus).", "content": "Pathogenesis of Trypanosoma equiperdum in deer mice (Peromyscus maniculatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210290"} {"pmid": "4210293", "title": "Acute transmural myocardial infarction. Its occurrence in a young man without demonstrable coronary artery disease.", "content": "Acute transmural myocardial infarction. Its occurrence in a young man without demonstrable coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210293"} {"pmid": "4210295", "title": "Familial hepatic cirrhosis in infants associated with alpha1-antitrypsin SZ phenotype.", "content": "Familial hepatic cirrhosis in infants associated with alpha1-antitrypsin SZ phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210295"} {"pmid": "4210294", "title": "Management of childhood asthma in Britain.", "content": "Management of childhood asthma in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210294"} {"pmid": "4210296", "title": "X-linked B lymphocyte deficiency. I. Panhypo-gamma-globulinemia and dys-gamma-globulinemia in siblings.", "content": "X-linked B lymphocyte deficiency. I. Panhypo-gamma-globulinemia and dys-gamma-globulinemia in siblings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210296"} {"pmid": "4210297", "title": "Comparative pharmacokinetics of amikacin and kanamycin.", "content": "Comparative pharmacokinetics of amikacin and kanamycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210297"} {"pmid": "4210298", "title": "Bioequivalency of generic and brand-named chlorpromazine.", "content": "Bioequivalency of generic and brand-named chlorpromazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210298"} {"pmid": "4210299", "title": "Allozyme variation in the fruit flies Dacus tryoni and Dacus neohumeralis (Tephritidae).", "content": "Allozyme variation in the fruit flies Dacus tryoni and Dacus neohumeralis (Tephritidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210299"} {"pmid": "4210300", "title": "Phenol oxidase activity and the lozenge locus of Drosophila melanogaster.", "content": "Phenol oxidase activity and the lozenge locus of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210300"} {"pmid": "4210301", "title": "Adh-n5: a temperature-sensitive mutant at the Adh locus in Drosophila.", "content": "Adh-n5: a temperature-sensitive mutant at the Adh locus in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210301"} {"pmid": "4210302", "title": "Two new antisickling agents and the use of amino acid salts.", "content": "Two new antisickling agents and the use of amino acid salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210302"} {"pmid": "4210303", "title": "Assay of serum folate: difference in serum folate values obtained by L. casei bioassay and competitive protein-binding assay.", "content": "Assay of serum folate: difference in serum folate values obtained by L. casei bioassay and competitive protein-binding assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210303"} {"pmid": "4210304", "title": "A simple procedure for the isolation of IgG anti-nuclear antibodies from human serum.", "content": "A simple procedure for the isolation of IgG anti-nuclear antibodies from human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210304"} {"pmid": "4210305", "title": "A new colorimetric method for the determination of glutathione in erythrocytes.", "content": "A new colorimetric method for the determination of glutathione in erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210305"} {"pmid": "4210307", "title": "Occupational allergy to animal dander and sera.", "content": "Occupational allergy to animal dander and sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210307"} {"pmid": "4210308", "title": "Synthesis of free ATP from membrane-bound ATP in chromatophores of Rhodospirillum rubrum.", "content": "Synthesis of free ATP from membrane-bound ATP in chromatophores of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210308"} {"pmid": "4210309", "title": "Polarized light spectroscopy of photosynthetic membranes in magneto-oriented whole cells and chloroplasts. Fluorescence and dichroism.", "content": "Polarized light spectroscopy of photosynthetic membranes in magneto-oriented whole cells and chloroplasts. Fluorescence and dichroism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210309"} {"pmid": "4210316", "title": "Neuronal mechanism of the disynaptic inhibition evoked in primate spinal motoneurones from the corticospinal tract.", "content": "Neuronal mechanism of the disynaptic inhibition evoked in primate spinal motoneurones from the corticospinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210316"} {"pmid": "4210317", "title": "Effects of selective frontal lobe lesions on response to separation in adolescent rhesus monkeys.", "content": "Effects of selective frontal lobe lesions on response to separation in adolescent rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210317"} {"pmid": "4210318", "title": "Proteins in bull rete testis and cauda epididymidia plasma.", "content": "Proteins in bull rete testis and cauda epididymidia plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210318"} {"pmid": "4210321", "title": "Induction of mitotic gene conversion in Saccharomyces cerevisiae by N-nitrosated pesticides.", "content": "Induction of mitotic gene conversion in Saccharomyces cerevisiae by N-nitrosated pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210321"} {"pmid": "4210322", "title": "A cytogenetic analysis of x-ray induced \"visible\" mutations at the yellow locus of Drosophila melanogaster.", "content": "A cytogenetic analysis of x-ray induced \"visible\" mutations at the yellow locus of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210322"} {"pmid": "4210323", "title": "The effect of caffeine on repair systems in oocytes of Drosophila melanogaster. I.", "content": "The effect of caffeine on repair systems in oocytes of Drosophila melanogaster. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210323"} {"pmid": "4210325", "title": "ATP-dependent deoxyribonuclease in Bacillus subtilis and a mutant deficient in this activity.", "content": "ATP-dependent deoxyribonuclease in Bacillus subtilis and a mutant deficient in this activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210325"} {"pmid": "4210320", "title": "Coacervate systems and origin of life.", "content": "Coacervate systems and origin of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210320"} {"pmid": "4210326", "title": "Modification of radiation-induced genetic damage in Drosophila melanogaster male germ cells with nucleic acid precursors. 3. Effects on the premeiotic cells.", "content": "Modification of radiation-induced genetic damage in Drosophila melanogaster male germ cells with nucleic acid precursors. 3. Effects on the premeiotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210326"} {"pmid": "4210327", "title": "Differences in the mother-infant relations of squirrel monkeys housed in social and restricted environments.", "content": "Differences in the mother-infant relations of squirrel monkeys housed in social and restricted environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210327"} {"pmid": "4210328", "title": "Social preferences of mother and infant squirrel monkeys following different rearing experiences.", "content": "Social preferences of mother and infant squirrel monkeys following different rearing experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210328"} {"pmid": "4210319", "title": "The development and diversification of Precambrian life.", "content": "The development and diversification of Precambrian life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210319"} {"pmid": "4210330", "title": "Virulence of Pseudomonas aeruginosa and spontaneous spread of pseudomonas pneumonia in a mink ranch.", "content": "Virulence of Pseudomonas aeruginosa and spontaneous spread of pseudomonas pneumonia in a mink ranch. Comparative studies on the virulence of two strains of Pseudomonas aeruginosa isolated from otic pus and mink pneumonic lesion, respectively, were made by means of intranasal inoculation in mink. The minimal lethal dose of the former (strain NC-5, highly virulent for mice) was 10(10), and that of the latter (strain No. 5, moderately virulent for mice) was 5.5 x 10(6). By planting droplets of P. aeruginosa suspension on the mink in the wire cages, an enzootic lethal pneumonia was brought about in a ranch. This disease spread to the neighboring 12 mink in turn, in one direction, with new cases occurring every day or every other day for 13 days.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210330"} {"pmid": "4210331", "title": "Mycobacterial components responsible for the induction of a chronic immunological inflammatory response in rabbit lungs.", "content": "Mycobacterial components responsible for the induction of a chronic immunological inflammatory response in rabbit lungs. Fractions of the tubercle bacillus were examined for their capacity to produce an allergic pulmonary granulomatous response in rabbits. We found that emulsions containing old tuberculin and even old tuberculin alone in an emulsion could induce a pulmonary inflammatory reaction comparable in intensity to that produced with killed BCG. Emulsions lacking old tuberculin failed to produce an allergic pulmonary inflammatory response. The significance of these results in relation to immunological and nonimmunological chronic inflammation is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210331"} {"pmid": "4210333", "title": "T cell dependence of macrophage activation and mobilization during infection with Mycobacterium tuberculosis.", "content": "T cell dependence of macrophage activation and mobilization during infection with Mycobacterium tuberculosis. Mice made T cell-deficient as adults by thymectomy and lethal irradiation, and infected with Mycobacterium tuberculosis, showed a greatly reduced capacity to develop nonspecific resistance to challenge with a heterologous bacterium. The capacity to develop nonspecific resistance was restored, however, by an infusion of syngeneic thymocytes. Evidence was presented which showed that the capacity of mycobacteria-infected mice to resist a lethal challenge with a heterologous organism rested on the capacity of macrophages existing at the time of challenge to reduce the number of challenge organisms to a sublethal level within 8 h. This antibacterial activity of macrophages was substantially reduced in T cell-deficient mice but could be restored by an infusion of syngeneic thymocytes. It was concluded that T cell-deficient mice have a reduced capacity to mobilize and activate macrophages because of their reduced capacity to respond immunologically to antigens of M. tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210333"} {"pmid": "4210332", "title": "Phagocytosis of live versus heat-killed bacteria by human polymorphonuclear leukocytes.", "content": "Phagocytosis of live versus heat-killed bacteria by human polymorphonuclear leukocytes. Heat-killed Pseudomonas aeruginosa are phagocytized much more slowly by human polymorphonuclear leukocytes than are the live organisms. The post-phagocytic increase in hexose monophosphate shunt activity (HMS) parallels the ingestion of the bacteria. The addition of serum to the live organisms causes a marked increase in both ingestion and cellular HMS activity; serum actually causes an inhibition of both uptake and HMS activity when added to the heat-killed organisms. Differences in postphagocytic HMS activity between live and heat-killed organisms were observed with three different species of bacteria, indicating that the phenomenon is not restricted to P. aeruginosa. These data emphasize that the influence of the particle on the phagocytic process is considerable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210332"} {"pmid": "4210334", "title": "Immunity to Candida albicans induced by Listeria monocytogenes.", "content": "Immunity to Candida albicans induced by Listeria monocytogenes. Immunity to Candida albicans was studied in Swiss-Webster white female mice. Lethal and sublethal infections with C. albicans did not enhance immunity to a subsequent Listeria monocytogenes challenge. Mice sensitized to L. monocytogenes and then challenged with C. albicans intravenously were able to reduce the population of C. albicans in their kidneys after being boosted (rechallenged) with L. monocytogenes. However, the acquired cellular immunity so induced was very short-lived. Both C. albicans-sensitized and nonsensitized control mice showed an immediate-type and delayed-type skin test response to the cell wall antigen(s) of C. albicans but not to the cytoplasmic antigen(s). There did not appear to be any correlation between increase in skin test response and progression of the candida infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210334"} {"pmid": "4210335", "title": "Purification and antigenicity of an M-like protein of Streptococcus equi.", "content": "Purification and antigenicity of an M-like protein of Streptococcus equi. A cell wall component of Streptococcus equi analogous to the M protein of group A streptococci has been identified and purified. A highly purified product has been obtained from cells by hot acid extraction, followed by acid precipitation, ammonium sulfate fractionation, and column chromatography. This product reacts with S. equi antiserum. The existence of this fraction in S. equi has been confirmed by the failure of trypsin-treated cells and their extracts to remove the long-chaining capacity of S. equi antiserum. The antigenicity of this M-like protein when incorporated in adjuvant has been assessed in rabbits and horses. In the rabbit, multiple doses of as low as 10 mug resulted in the production of serum capable of inducing long-chain formation and opsonizing and mouse protective antibody. Two doses of 100 mug elicited similar responses. The bactericidal capacity of this serum could be eliminated by absorption with whole S. equi cells or their extracts, but not by absorption with trypsin-treated cells or extracts therefrom. Horses vaccinated 15 months previously with a whole-cell killed vaccine and given 200 mug of the purified protein intramuscularly showed evidence of an anamnestic response to the antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210335"} {"pmid": "4210336", "title": "Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia cynthia pupae.", "content": "Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia cynthia pupae. Pupae of the silk moth, Samia cynthia, were found to contain an inducible antibacterial activity in their hemolymph. This immunity response was provoked by primary infections with either Escherichia coli K-12 or Enterobacter cloacae. In both cases the antibacterial activity was directed chiefly towards E. coli. During standard conditions, 1% of hemolymph could kill 10(3) to 10(4) viable E. coli, strain D31, within 5 min. A lower level of antibacterial activity was induced by injections of a sterile salt solution. The killing of strain D31 followed single-hit kinetics, and increasing rate constants were obtained for increasing amounts of hemolymph. The reaction was sensitive to pretreatment with trypsin and it was protected by reducing agents. The activity was inhibited by microgram quantities of lipopolysaccharide (LPS) prepared from certain LPS mutants of E. coli K-12. A comparison of the susceptibility showed that \"heptose-less\" LPS mutants were more sensitive to killing than other strains. During standard conditions hemolymph will lyse both E. coli and Micrococcus lysodeikticus. Lysis of E. coli followed a multi-hit kinetics and it was inhibited by LPS, whereas lysis of M. lysodeikticus was unaffected by LPS. Hemolymph was fractionated on Sephadex G-200, and the lytic activities were recovered in partly overlapping peaks. Reconstitution with pooled fractions gave synergistic effects with the killing assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210336"} {"pmid": "4210337", "title": "Slime of Pseudomonas aeruginosa: in vivo production.", "content": "Slime of Pseudomonas aeruginosa: in vivo production. Indirect hemagglutination inhibition tests were employed to detect slime in concentrations as low as 1 mug/ml. Increasing concentrations of slime resulted in proportionately greater inhibition of hemagglutination. Peritoneal aspirates and plasma of mice injected with slime were shown to exhibit the inhibitory activity of slime. The rapid dissemination of slime into the peripheral circulation was also indicated by the hemagglutination of mouse erythrocytes by specific anti-slime serum. By similar methods, the inhibitory activity of slime was also detected in peritoneal aspirates and plasma of mice infected with lethal doses of viable Pseudomonas aeruginosa. Furthermore, the inhibitory activity was found to increase with time after viable cell infection, whereas such increases were not detected after the injection of heat-killed organisms. Ferritin-labeled slime antibodies were found to completely surround cells of Pseudomonas aeruginosa obtained from the peritoneal cavity of mice 5 h postinfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210337"} {"pmid": "4210338", "title": "Fish rhabdovirus replication in non-piscine cell culture: new system for the study of rhabdovirus-cell interaction in which the virus and cell have different temperature optima.", "content": "Fish rhabdovirus replication in non-piscine cell culture: new system for the study of rhabdovirus-cell interaction in which the virus and cell have different temperature optima. The replication of three rhabdoviruses associated with diseases of fish has been demonstrated in cells of continuously cultivated non-piscine cell lines. Spring viremia of carp (SVC) virus and the salmonid fish viruses, Egtved and infectious hematopoietic necrosis virus, all replicated in mammalian WI-38 (human diploid cell strain) and BHK/21 cells and in cells of one or more reptilian cell lines at the temperatures commonly used to propagate these viruses in fish cells. The infections were cytopathic: SVC virus plaque assays may be performed in several types of mammalian cell culture. \"Autointerference\" apparently mediated by abortive \"T\" particle formation was observed during serial nondiluted passages of SVC virus in BHK/21 and TH1 cells, but not in RTG-2 or WI-38 cells. Optimal temperatures for replication of SVC and Egtved viruses in BHK/21 cells were identical to those determined in poikilothermic vertebrate cell cultures. However, these viruses replicated relatively more efficiently at suboptimal temperatures in \"cold-blooded\" vertebrate cells than in the hamster cells. Studies of [(3)H]uridine incorporation into uninfected BHK/21 cells incubated at different temperatures revealed that [(3)H]uridine uptake is sharply reduced at temperatures below 24.5 C. Growth curve studies of SVC virus in BHK/21 cells incubated at 23 C revealed that a clear-cut large excess of virus-induced [(3)H]uridine incorporation could be demonstrated in the absence of actinomycin D. Actinomycin D treatment (1 mug/ml) led to efficient inhibition of control cell [(3)H]uridine uptake, but also markedly reduced the total counts per minute of virus-induced [(3)H]uridine uptake, without depressing the yield of released infectious virus. Actinomycin D added to SVC virus-infected BHK/21 cell cultures at concentrations as low as 0.01 mug/ml caused a significant decrease in the level of virus-induced [(3)H]uridine uptake, despite the fact that this concentration is insufficient to efficiently suppress \"background\" cellular [(3)H]uridine incorporation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210338"} {"pmid": "4210339", "title": "Ultrastructural studies of Rickettsia prowazeki from louse midgut cells to feces: search for \"dormant\" forms.", "content": "Ultrastructural studies of Rickettsia prowazeki from louse midgut cells to feces: search for \"dormant\" forms. An electron microscope study of infected human louse gut cells and feces was made to determine whether a valid correlation exists between the increased resistance of Rickettsia prowazeki (in the louse feces) to adverse environmental influences and changes in the organism which might be reflected in its ultrastructure. Upon fine structural examination of this intracellular parasite as it passed from the louse midgut cell to the feces, it was apparent that no such morphological changes had occurred.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210339"} {"pmid": "4210340", "title": "Immunodiffusion analysis of membranes of Thermoplasma acidophilum.", "content": "Immunodiffusion analysis of membranes of Thermoplasma acidophilum. Isolates of Thermoplasma acidophilum were divided into serological groups based on immunodiffusion studies of solubilized-membrane preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210340"} {"pmid": "4210341", "title": "Interferon induction in mice by lipopolysaccharide from Brucella abortus.", "content": "Interferon induction in mice by lipopolysaccharide from Brucella abortus. Endotoxin or lipopolysaccharide isolated from Brucella abortus (strain 456) produced a typical endotoxin-type interferon response in mice with peak levels of the inhibitor occurring 2 h after intravenous injection of the stimuli. Brucella lipopolysaccharide was a much less effective interferon stimulus than the lipopolysaccharide isolated from Salmonella typhimurium (strain LT-2).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210341"} {"pmid": "4210344", "title": "Pectinase activities in some fungi.", "content": "Pectinase activities in some fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210344"} {"pmid": "4210345", "title": "Isolation and characterization of ribosomes from Streptomyces griseus spores.", "content": "Isolation and characterization of ribosomes from Streptomyces griseus spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210345"} {"pmid": "4210346", "title": "Observations on the reproducibility of the bromelised test cell anti-D assay using the auto-analyser.", "content": "Observations on the reproducibility of the bromelised test cell anti-D assay using the auto-analyser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210346"} {"pmid": "4210348", "title": "Blood-group-like substances in some marine invertebrates. I. Blood-group A reactive substances in the ascidian Phallusia mammilata (Cuvier) and in the lancelet Amphioxus (branchiostoma) lanceolatus (Pallas).", "content": "Blood-group-like substances in some marine invertebrates. I. Blood-group A reactive substances in the ascidian Phallusia mammilata (Cuvier) and in the lancelet Amphioxus (branchiostoma) lanceolatus (Pallas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210348"} {"pmid": "4210347", "title": "Efficiency of anti-D IgG prevention after induced abortion.", "content": "Efficiency of anti-D IgG prevention after induced abortion. A study was conducted to investigate the efficacy of anti-D immunoglobulin prevention after induced abortion. Serological data of Rh(D)-negative women whose pregnancies were terminated and who were given anti-D IgG in 1971 and 1972 in Hungary were compiled. During the 2 years, a total of 8986 women undergoing abortion were given anti-D IgG. Among these were 2419 primigravidae. Of these, subsequent serological tests could be performed in 1588. At the 3- and 6-month control examinations anti-D IgG could be demonstrated in 4 patients. The figure amounts to a failure rate of .25%.. 2 of the 4 patients proved to be positive only by the papain test. When using the risk figures reported in the literature, it was determined that anti-D prophylaxis diminishes immunization of the abortion recipient to about 1/20. It is concluded that results of the prophylaxis and the observation that 38% of the women undergoing induced abortion are young justify the opinion of those who advocate administration of anti-D in induced abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210347"} {"pmid": "4210349", "title": "Bone growth in protein calorie malnutrition.", "content": "Bone growth in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210349"} {"pmid": "4210353", "title": "Protein-calorie malnutrition in children and its relation to psychological development and behavior.", "content": "Protein-calorie malnutrition in children and its relation to psychological development and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210353"} {"pmid": "4210354", "title": "Blepharmone: a conjugation-inducing glycoprotein in the ciliate blepharisma.", "content": "Blepharmone: a conjugation-inducing glycoprotein in the ciliate blepharisma. Gamone 1 of Blepharisma intermedium was isolated, identified as a slightly basic glycoprotein (mizoleclular weight, 2 x 10(5)), and designated as blepharmnone. At the concentration of 6 x 10(-8) milligram per milliliter, it specifically transforms matinig type 2 cells, so that they can conjugate in about 2 hours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210354"} {"pmid": "4210355", "title": "Initiation of the transcription of phi29 DNA by Bacillus subtilis RNA polymerase.", "content": "Initiation of the transcription of phi29 DNA by Bacillus subtilis RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210355"} {"pmid": "4210356", "title": "Effect of an epipodophyllotoxin derivative (VP 16-213) on macromolecular synthesis and mitosis in mastocytoma cells in vitro.", "content": "Effect of an epipodophyllotoxin derivative (VP 16-213) on macromolecular synthesis and mitosis in mastocytoma cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210356"} {"pmid": "4210351", "title": "Two years study on sugar intolerance in Indonesian children.", "content": "Two years study on sugar intolerance in Indonesian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210351"} {"pmid": "4210357", "title": "Immunochemical studies on duck (Anas platyrhynchos) ovotransferrin-isolation, isoelectric fractionation and antigen-antibody reaction.", "content": "Immunochemical studies on duck (Anas platyrhynchos) ovotransferrin-isolation, isoelectric fractionation and antigen-antibody reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210357"} {"pmid": "4210350", "title": "Schönlein-Henoch syndrome in a case of protein calorie malnutrition (case report).", "content": "Schönlein-Henoch syndrome in a case of protein calorie malnutrition (case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210350"} {"pmid": "4210358", "title": "Metabolic clearance rate of progesterone during lactation in the Rhesus monkey.", "content": "Metabolic clearance rate of progesterone during lactation in the Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210358"} {"pmid": "4210359", "title": "Evidence for multiple polypeptide chains in the membrane protein spectrin.", "content": "Evidence for multiple polypeptide chains in the membrane protein spectrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210359"} {"pmid": "4210360", "title": "Human liver aminopeptidase. Role of metal ions in mechanism of action.", "content": "Human liver aminopeptidase. Role of metal ions in mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210360"} {"pmid": "4210362", "title": "Effect of reaction conditions on the reassociation of divergent deoxyribonucleic acid sequences.", "content": "Effect of reaction conditions on the reassociation of divergent deoxyribonucleic acid sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210362"} {"pmid": "4210361", "title": "Identity of the Fc fragments of pathological and normal human immunoglobulin M.", "content": "Identity of the Fc fragments of pathological and normal human immunoglobulin M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210361"} {"pmid": "4210363", "title": "Three-segment RNA genome of Lumbo virus (Bunyavirus).", "content": "Three-segment RNA genome of Lumbo virus (Bunyavirus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210363"} {"pmid": "4210364", "title": "Localized humoral immunity with particular reference to ruminants.", "content": "Localized humoral immunity with particular reference to ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210364"} {"pmid": "4210365", "title": "A new acidic protease in human seminal plasma.", "content": "A new acidic protease in human seminal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210365"} {"pmid": "4210366", "title": "The reassociation of ribosomal subunits from the muscle of normal and diabetic animals.", "content": "The reassociation of ribosomal subunits from the muscle of normal and diabetic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210366"} {"pmid": "4210367", "title": "Dissociation of skeletal muscle ribosomes from normal and diabetic animals by initiation factors EIF-3.", "content": "Dissociation of skeletal muscle ribosomes from normal and diabetic animals by initiation factors EIF-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210367"} {"pmid": "4210368", "title": "Studies on anti-poly(adenosine diphosphate ribose) antibody.", "content": "Studies on anti-poly(adenosine diphosphate ribose) antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210368"} {"pmid": "4210372", "title": "Skin disinfection with ethanol, without and with additives.", "content": "Skin disinfection with ethanol, without and with additives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210372"} {"pmid": "4210373", "title": "Aflatoxins in mutants of Aspergillus flavus.", "content": "Aflatoxins in mutants of Aspergillus flavus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210373"} {"pmid": "4210375", "title": "A radioisotope study of the vascular response to sagittal split osteotomy of the mandibular ramus.", "content": "A radioisotope study of the vascular response to sagittal split osteotomy of the mandibular ramus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210375"} {"pmid": "4210376", "title": "Letter: Volumes of injections in mice.", "content": "Letter: Volumes of injections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210376"} {"pmid": "4210377", "title": "Studies on cell adhesion in tissue culture. XV. Some effects of cycloheximide on cell detachment.", "content": "Studies on cell adhesion in tissue culture. XV. Some effects of cycloheximide on cell detachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210377"} {"pmid": "4210378", "title": "EM autoradiographic studies on polytene nuclei of Drosophila melanogaster. II. Organization and transcriptive activity of the chromocentre.", "content": "EM autoradiographic studies on polytene nuclei of Drosophila melanogaster. II. Organization and transcriptive activity of the chromocentre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210378"} {"pmid": "4210379", "title": "Disinfecting hydrotherapy equipment.", "content": "Disinfecting hydrotherapy equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210379"} {"pmid": "4210380", "title": "Hemispheric differences in the discrimination of line orientation.", "content": "Hemispheric differences in the discrimination of line orientation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210380"} {"pmid": "4210381", "title": "The effects of posterior cortical lesions on eye orientation during visual discrimination by monkeys.", "content": "The effects of posterior cortical lesions on eye orientation during visual discrimination by monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210381"} {"pmid": "4210382", "title": "Cerebral dominance in monkeys?", "content": "Cerebral dominance in monkeys?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210382"} {"pmid": "4210374", "title": "Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi.", "content": "Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210374"} {"pmid": "4210384", "title": "Detection of IgM heterogeneity dependent on the support medium of immunoelectrophoresis.", "content": "Detection of IgM heterogeneity dependent on the support medium of immunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210384"} {"pmid": "4210385", "title": "An assay of bilirubin UDP-glucuronyl transferase on needle-biopsies applied to Gilbert's syndrome.", "content": "An assay of bilirubin UDP-glucuronyl transferase on needle-biopsies applied to Gilbert's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210385"} {"pmid": "4210383", "title": "Plasma cell dyscrasias (except myeloma).", "content": "Plasma cell dyscrasias (except myeloma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210383"} {"pmid": "4210386", "title": "An assessment of the suitability of bromocresol green for the determination of serum albumin.", "content": "An assessment of the suitability of bromocresol green for the determination of serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210386"} {"pmid": "4210387", "title": "Recovery from malnutrition: food preference and neophobia.", "content": "Recovery from malnutrition: food preference and neophobia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210387"} {"pmid": "4210390", "title": "Relations of HL-A and Rh systems to immune reactivity. Joint report of the results of 'HL-A and immune response' workshop, Budapest 1972.", "content": "Relations of HL-A and Rh systems to immune reactivity. Joint report of the results of 'HL-A and immune response' workshop, Budapest 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210390"} {"pmid": "4210391", "title": "Production of cycloheximide by Streptomyces sp.", "content": "Production of cycloheximide by Streptomyces sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210391"} {"pmid": "4210392", "title": "Serological studies on toxoplasmosis in patients with typhoid fever.", "content": "Serological studies on toxoplasmosis in patients with typhoid fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210392"} {"pmid": "4210393", "title": "The histaminase activity of guinea-pig's plasma during experimental inflammation. II. Some properties of the enzyme.", "content": "The histaminase activity of guinea-pig's plasma during experimental inflammation. II. Some properties of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210393"} {"pmid": "4210394", "title": "Practical application of a simplified vitamin B12 radioassay.", "content": "Practical application of a simplified vitamin B12 radioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210394"} {"pmid": "4210395", "title": "Total nutrition by peripheral vein--the lipid system.", "content": "Total nutrition by peripheral vein--the lipid system. A means for providing total nutrition is described in which 10% soybean oil-eggyolk phosphatide-glycerol emulsion (Intralipid) and a solution of 5% dextrose in 5% protein hydrolysate are given simultaneously into a peripheral vein, utilizing two giving sets united by a Y-connector at the needle. No ketonuria occurred, and there were no side effects from the lipid emulsion. Advantages of this system include absence of significant peripheral phlebitis, avoidance of the hazards of caval catheters, and absence of the complications of hypertonic solutions. Disadvantages include restricted forearm movement and frequent regulation of flow-rates.This system was used in 23 patients for periods of 4 to 78 days (mean 16.3 days). Weight gain and healing occurred, and all survived but one patient who died of myocardial infarction following successful surgical closure of an enterocolocutaneous fistula. The lipid system adds another method to the measures available for the management of major nutritional problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210395"} {"pmid": "4210397", "title": "A comparison of nutritional gains resulting from intravenous and enteral feeding.", "content": "A comparison of nutritional gains resulting from intravenous and enteral feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210397"} {"pmid": "4210396", "title": "Coronary hypertonia and angina.", "content": "Coronary hypertonia and angina. Coronary hypertonia was observed in a patient with unstable angina. It was possible on one occasion to reproduce the clinical picture, electrocardiographic changes, lactate production and coronary hypertonia by means of atrial pacing. He had a normal left coronary arteriogram when the diffuse spasm was relieved by nitroglycerin. Therefore hypertonia (or spasm) of the left coronary artery was believed to be the cause of his variant angina with subendocardial ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210396"} {"pmid": "4210398", "title": "Energy requirement in regenerative and atrophic processes of the liver in man and other mammals.", "content": "Energy requirement in regenerative and atrophic processes of the liver in man and other mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210398"} {"pmid": "4210399", "title": "Myocardial viability after transient ischemia in primates.", "content": "Myocardial viability after transient ischemia in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210399"} {"pmid": "4210400", "title": "Bacterial growth inhibition by amniotic fluid. I. In vitro evidence for bacterial growth-inhibiting activity.", "content": "Bacterial growth inhibition by amniotic fluid. I. In vitro evidence for bacterial growth-inhibiting activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210400"} {"pmid": "4210402", "title": "Congenital lesions of the inner ear, demonstrated by tomography.", "content": "Congenital lesions of the inner ear, demonstrated by tomography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210402"} {"pmid": "4210404", "title": "Cochlear electrical activity in noise-induced hearing lossmbehavioral and electrophysiological studies in primates.", "content": "Cochlear electrical activity in noise-induced hearing lossmbehavioral and electrophysiological studies in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210404"} {"pmid": "4210401", "title": "Maternal mumps infection during gestation: observations on the progeny.", "content": "Maternal mumps infection during gestation: observations on the progeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210401"} {"pmid": "4210403", "title": "The ganglion on the internal laryngeal nerve.", "content": "The ganglion on the internal laryngeal nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210403"} {"pmid": "4210405", "title": "Transport of lead 203 and calcium 47 from mother to offspring.", "content": "Transport of lead 203 and calcium 47 from mother to offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210405"} {"pmid": "4210406", "title": "Organized labor and the prepaid group practice movement.", "content": "Organized labor and the prepaid group practice movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210406"} {"pmid": "4210407", "title": "Response of the left ventricle to nitroglycerin in patients with and without mitral regurgitation.", "content": "Response of the left ventricle to nitroglycerin in patients with and without mitral regurgitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210407"} {"pmid": "4210416", "title": "On the control of gonadotropin secretion in the rhesus monkey.", "content": "On the control of gonadotropin secretion in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210416"} {"pmid": "4210412", "title": "Prevention of Rh-immunization in Sweden.", "content": "Prevention of Rh-immunization in Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210412"} {"pmid": "4210413", "title": "Management of pregnancy complicated by Rh-immunization. Review with respect to own investigations and results.", "content": "Management of pregnancy complicated by Rh-immunization. Review with respect to own investigations and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210413"} {"pmid": "4210425", "title": "IgG levels in amniotic fluid.", "content": "IgG levels in amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210425"} {"pmid": "4210424", "title": "Elastase of Pseudomonas aeruginosa: inactivation of complement components and complement-derived chemotactic and phagocytic factors.", "content": "Elastase of Pseudomonas aeruginosa: inactivation of complement components and complement-derived chemotactic and phagocytic factors. A purified elastase from Pseudomonas aeruginosa was highly destructive for fluid-phase and cell-bound C1 and C3 and fluid-phase C5, C8, and C9. Inactivation of C4, C2, C6, and C7 by the enzyme varied from 0 to 67%. Low concentrations of elastase generated, then inactivated, a chemotactic factor from human C5 but not from C3. Higher enzyme concentrations inactivated the C5 chemotactic activity at a faster rate. Elastase treatment of sensitized pseudomonads containing cell-bound C3 reduced the phagocytic indexes of polymorphonuclear leukocytes. The data support the proposed chemopathogenic role of the elastase in generation of the characteristic non-inflammatory Pseudomonas vasculitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210424"} {"pmid": "4210426", "title": "Escherichia coli gene transfer to unrelated bacteria by a histidine operon--RP1 drug resistance plasmic complex.", "content": "Escherichia coli gene transfer to unrelated bacteria by a histidine operon--RP1 drug resistance plasmic complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210426"} {"pmid": "4210427", "title": "Complement and antibody in self-agglutinating human semen.", "content": "Complement and antibody in self-agglutinating human semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210427"} {"pmid": "4210428", "title": "\"Lower\" gastrointestinal tract hemorrhage: new concepts based on arteriography.", "content": "\"Lower\" gastrointestinal tract hemorrhage: new concepts based on arteriography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210428"} {"pmid": "4210430", "title": "Management of juvenile laryngeal papilloma: further observations.", "content": "Management of juvenile laryngeal papilloma: further observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210430"} {"pmid": "4210431", "title": "Adaptive responses to total intravenous feeding.", "content": "Adaptive responses to total intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210431"} {"pmid": "4210432", "title": "Neurophysiological effects of dorsal column stimulation in man and monkey.", "content": "Neurophysiological effects of dorsal column stimulation in man and monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210432"} {"pmid": "4210433", "title": "Multiple IgM autoantibodies in a nonhuman primate.", "content": "Multiple IgM autoantibodies in a nonhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210433"} {"pmid": "4210434", "title": "The inactivator of the first component of human complement (C1INA). The complex formation with the activated first component of human complement (C1) or with its subcomponents.", "content": "The inactivator of the first component of human complement (C1INA). The complex formation with the activated first component of human complement (C1) or with its subcomponents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210434"} {"pmid": "4210435", "title": "Structure and biochemistry of phloem-proteins isolated from Cucurbita maxima.", "content": "Structure and biochemistry of phloem-proteins isolated from Cucurbita maxima.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210435"} {"pmid": "4210436", "title": "Neisseria meningitidis serogroup Y: incidence and description of clinical illness.", "content": "Neisseria meningitidis serogroup Y: incidence and description of clinical illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210436"} {"pmid": "4210437", "title": "Cromolyn sodium therapy for chronic perennial asthma. A double-blind study of 40 children.", "content": "Cromolyn sodium therapy for chronic perennial asthma. A double-blind study of 40 children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210437"} {"pmid": "4210438", "title": "Frequency of the ocular choroid blush during arteriography.", "content": "Frequency of the ocular choroid blush during arteriography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210438"} {"pmid": "4210439", "title": "Feather keratin--analysis of subunit heterogeneity.", "content": "Feather keratin--analysis of subunit heterogeneity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210439"} {"pmid": "4210441", "title": "The Lansing effect revisited. I. Life-span.", "content": "The Lansing effect revisited. I. Life-span.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210441"} {"pmid": "4210442", "title": "Pulmonary tuberculosis in free-living lechwe antelope in Zambia.", "content": "Pulmonary tuberculosis in free-living lechwe antelope in Zambia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210442"} {"pmid": "4210443", "title": "A pathogenic theilerial syndrome of cattle in the Narok District of Kenya. I. Transmission studies.", "content": "A pathogenic theilerial syndrome of cattle in the Narok District of Kenya. I. Transmission studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210443"} {"pmid": "4210444", "title": "A pathogenic theilerial syndrome of cattle in the Narok District of Kenya. II. Serological studies.", "content": "A pathogenic theilerial syndrome of cattle in the Narok District of Kenya. II. Serological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210444"} {"pmid": "4210445", "title": "East Coast Fever: field challenge of cattle immunised against Theileria parva (Muguga).", "content": "East Coast Fever: field challenge of cattle immunised against Theileria parva (Muguga).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210445"} {"pmid": "4210446", "title": "Sarcosporidiosis-a review.", "content": "Sarcosporidiosis-a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210446"} {"pmid": "4210447", "title": "Effects of nutritional state and of administration of glucose, glibenclamide or diazoxide on the storage of amylase in mouse pancreas.", "content": "Effects of nutritional state and of administration of glucose, glibenclamide or diazoxide on the storage of amylase in mouse pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210447"} {"pmid": "4210453", "title": "Identification of Neisseria gonorrhoeae in synovial membrane by electron microscopy.", "content": "Identification of Neisseria gonorrhoeae in synovial membrane by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210453"} {"pmid": "4210454", "title": "Trends in disease caused by Neisseria meningitidis: 1972 and 1973.", "content": "Trends in disease caused by Neisseria meningitidis: 1972 and 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210454"} {"pmid": "4210455", "title": "Computerized system for stimulus generation, control, behavioral data acquisition and summary for primate visual psychophysics.", "content": "Computerized system for stimulus generation, control, behavioral data acquisition and summary for primate visual psychophysics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210455"} {"pmid": "4210456", "title": "Protein deprivation in primates. 3. Cage activities and chain-pulling behavior of adult rhesus monkeys maintained on low-protein diets.", "content": "Protein deprivation in primates. 3. Cage activities and chain-pulling behavior of adult rhesus monkeys maintained on low-protein diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210456"} {"pmid": "4210457", "title": "Clozapine--a new antipsychotic agent.", "content": "Clozapine--a new antipsychotic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210457"} {"pmid": "4210458", "title": "Clozapine--a potential antipsychotic agent without extrapyramidal manifestations.", "content": "Clozapine--a potential antipsychotic agent without extrapyramidal manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210458"} {"pmid": "4210459", "title": "A double-blind comparison of once-a-day pimozide, trifluoperazine, and placebo in the maintenance care of chronic schizophrenic outpatients.", "content": "A double-blind comparison of once-a-day pimozide, trifluoperazine, and placebo in the maintenance care of chronic schizophrenic outpatients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210459"} {"pmid": "4210460", "title": "Orgotein: a new anti-inflammatory metalloprotein drug: preliminary evaluation of clinical efficacy and safety in degenerative joint disease.", "content": "Orgotein: a new anti-inflammatory metalloprotein drug: preliminary evaluation of clinical efficacy and safety in degenerative joint disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210460"} {"pmid": "4210449", "title": "The severity of lactose intolerance in Indonesian children.", "content": "The severity of lactose intolerance in Indonesian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210449"} {"pmid": "4210461", "title": "Double-blind study of the analgesic effect of ethoheptazine-aspirin.", "content": "Double-blind study of the analgesic effect of ethoheptazine-aspirin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210461"} {"pmid": "4210462", "title": "A double-blind study to assess the efficacy of oral tilidine hydrochloride (W5759A)among a group of post-operative orthopedic and trauma patients.", "content": "A double-blind study to assess the efficacy of oral tilidine hydrochloride (W5759A)among a group of post-operative orthopedic and trauma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210462"} {"pmid": "4210463", "title": "Controlled-release potassium supplementation.", "content": "Controlled-release potassium supplementation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210463"} {"pmid": "4210464", "title": "Gastrointestinal blood loss in patients receiving acetylsalicylic acid or diftalone, a new antiinflammatory drug: a comparative evaluation.", "content": "Gastrointestinal blood loss in patients receiving acetylsalicylic acid or diftalone, a new antiinflammatory drug: a comparative evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210464"} {"pmid": "4210465", "title": "Evaluation of corticosteroids intended for use as topical anti-inflammatory drugs.", "content": "Evaluation of corticosteroids intended for use as topical anti-inflammatory drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210465"} {"pmid": "4210466", "title": "Immunopathological studies in patients with farmer's lung.", "content": "Immunopathological studies in patients with farmer's lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210466"} {"pmid": "4210467", "title": "Septicaemia and meningitis caused by Neisseria mucosa varietas heidelbergensis.", "content": "Septicaemia and meningitis caused by Neisseria mucosa varietas heidelbergensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210467"} {"pmid": "4210468", "title": "The histaminase activity of guinea-pig's plasma during experimental inflammation. I. The enzyme activity.", "content": "The histaminase activity of guinea-pig's plasma during experimental inflammation. I. The enzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210468"} {"pmid": "4210470", "title": "Differentiation and medical importance of saccharolytic intestinal Bacteroides.", "content": "Differentiation and medical importance of saccharolytic intestinal Bacteroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210470"} {"pmid": "4210471", "title": "Mycobacterial proficiency testing in the Quality Evaluation Programs of the College of American Pathologists, 1972.", "content": "Mycobacterial proficiency testing in the Quality Evaluation Programs of the College of American Pathologists, 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210471"} {"pmid": "4210476", "title": "Pulmonary bacterial susceptibility in the burned rat.", "content": "Pulmonary bacterial susceptibility in the burned rat. An in vivo model system, using the burned rat as a model of altered host resistance, was developed and studied to investigate the lung's ability to handle an aerosolized bacterial insult of either P. aeruginosa or S. aureus. Rates of lung bacterial clearance were correlated with mortality, bacteriologic and histologic results. Susceptibility of the lung to sepsis was shown to be directly related to host resistance and was significantly increased following cutaneous thermal injury. Exposure of burned, non-seeded rats to a bacterial aerosol on day one post burn resulted in a mortality of 50% (P. aeruginosa) and 11.1% (S. aureus). This mortality clearly demonstrates an increased susceptibility at day one post burn. In contrast, this susceptibility gradually decreased with time; no mortality in the burned rat when exposed on day six post burn or in the normal, unburned rat. Histologic findings correlate well with the mortality results showing a gradually decreasing severity of pneumonitis if aerosol exposure was further delayed. Lung bacterial clearance studies revealed that the initial good response of the pulmonary defense mechanisms immediately following aerosol challenge are short-lived and that a marked increase in pulmonary bacterial susceptibility occurs as early as 24 hours following thermal injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210476"} {"pmid": "4210477", "title": "Pancreatic secretion in response to jejunal feeding of elemental diet.", "content": "Pancreatic secretion in response to jejunal feeding of elemental diet. The instillation of elemental diet into the proximal jejunum of dogs results in a brisk pancreatic secretory response, but the fluid is watery and \"enzyme-poor.\" The administration of the caloric equivalent in a standard blenderized ward diet induces pancreatic enzyme secretion. Although elemental diet does not \"rest\" the pancreas, the failure of these preparations to stimulate pancreatic enzyme secretion gives them a theoretical advantage as a nutritional source in the convalescent phase of acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210477"} {"pmid": "4210474", "title": "Two-site model for human dental enamel dissolution in EDTA.", "content": "Two-site model for human dental enamel dissolution in EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210474"} {"pmid": "4210472", "title": "Plaque formation by mixed cultures of nonprimary plaque-forming microorganisms.", "content": "Plaque formation by mixed cultures of nonprimary plaque-forming microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210472"} {"pmid": "4210482", "title": "Development of antennal imaginal disks in Drosophila melanogaster by induced mosaicism. Experiments with strains y sn ++ and y sn ++; ssa.", "content": "Development of antennal imaginal disks in Drosophila melanogaster by induced mosaicism. Experiments with strains y sn ++ and y sn ++; ssa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210482"} {"pmid": "4210481", "title": "Studies in immunodermatology. V. Basement membrane and reticulin antigens in human sera.", "content": "Studies in immunodermatology. V. Basement membrane and reticulin antigens in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210481"} {"pmid": "4210473", "title": "Effects of tetracyclines on membranous bone growth and dentin apposition in young rhesus monkeys.", "content": "Effects of tetracyclines on membranous bone growth and dentin apposition in young rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210473"} {"pmid": "4210475", "title": "Electromyography of the mandibular postural position in the rhesus monkey (Macaca mulatta).", "content": "Electromyography of the mandibular postural position in the rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210475"} {"pmid": "4210483", "title": "Antagonistic effects of glutamine and histamine on in vitro lysozyme activity.", "content": "Antagonistic effects of glutamine and histamine on in vitro lysozyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210483"} {"pmid": "4210485", "title": "Instrumented PVP-augmented antiglobulin tests. I. Detection of allogeneic antibodies coating otherwise normal erythrocytes.", "content": "Instrumented PVP-augmented antiglobulin tests. I. Detection of allogeneic antibodies coating otherwise normal erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210485"} {"pmid": "4210486", "title": "Navajo jaundice: a variant of neonatal hyperbilirubinemia associated with breast feeding.", "content": "Navajo jaundice: a variant of neonatal hyperbilirubinemia associated with breast feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210486"} {"pmid": "4210478", "title": "A self control method for long term anticoagulation therapy.", "content": "A self control method for long term anticoagulation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210478"} {"pmid": "4210488", "title": "Regulation of antibiotic production: catabolite inhibition and the dualistic effect of glucose on indolmycin production.", "content": "Regulation of antibiotic production: catabolite inhibition and the dualistic effect of glucose on indolmycin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210488"} {"pmid": "4210490", "title": "Metatropic dqarfism.", "content": "Metatropic dqarfism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210490"} {"pmid": "4210491", "title": "Primate red cell enzymes: glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase.", "content": "Primate red cell enzymes: glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210491"} {"pmid": "4210495", "title": "Observations on precipitins against a peptidase with chymotrypsin-like activity of Micropolyspora faeni, in sera of cattle exposed to mouldy hay.", "content": "Observations on precipitins against a peptidase with chymotrypsin-like activity of Micropolyspora faeni, in sera of cattle exposed to mouldy hay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210495"} {"pmid": "4210496", "title": "Eperythrozoon and Haemobartonella in monkeys.", "content": "Eperythrozoon and Haemobartonella in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210496"} {"pmid": "4210497", "title": "Ehnanced resistance to certain infections in vitamin A-treated mice.", "content": "Ehnanced resistance to certain infections in vitamin A-treated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210497"} {"pmid": "4210498", "title": "Augmentation of wound strength by pretreatment with epinephrine.", "content": "Augmentation of wound strength by pretreatment with epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210498"} {"pmid": "4210499", "title": "High levels of serum complement factors in juvenille rheumatoid arthritis.", "content": "High levels of serum complement factors in juvenille rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210499"} {"pmid": "4210500", "title": "Is chiasma determination sequential?", "content": "Is chiasma determination sequential?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210500"} {"pmid": "4210487", "title": "Use of marrow-cancellous bone grafts in maxillary alveolar and palatal clefts.", "content": "Use of marrow-cancellous bone grafts in maxillary alveolar and palatal clefts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210487"} {"pmid": "4210501", "title": "Haemocyanin synthesis and the branchial gland of Octopus.", "content": "Haemocyanin synthesis and the branchial gland of Octopus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210501"} {"pmid": "4210503", "title": "Biosynthesis of biopterin by Chinese hamster ovary (CHO K1) cell culture.", "content": "Biosynthesis of biopterin by Chinese hamster ovary (CHO K1) cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210503"} {"pmid": "4210502", "title": "Ribonucleotide reductase from Euglena gracilis. A 5'-deoxyadenoslycobalamin-dependent enzyme.", "content": "Ribonucleotide reductase from Euglena gracilis. A 5'-deoxyadenoslycobalamin-dependent enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210502"} {"pmid": "4210504", "title": "The interaction of a cationic detergent with bovine serum albumin and other proteins.", "content": "The interaction of a cationic detergent with bovine serum albumin and other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210504"} {"pmid": "4210505", "title": "Glycosphingolipids covalently linked to agarose gel or glass beads. Use of the compounds for purification of antibodies directed against globoside and hematoside.", "content": "Glycosphingolipids covalently linked to agarose gel or glass beads. Use of the compounds for purification of antibodies directed against globoside and hematoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210505"} {"pmid": "4210507", "title": "Isolation and properties of two inhibitors of proteinase B from yeast.", "content": "Isolation and properties of two inhibitors of proteinase B from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210507"} {"pmid": "4210506", "title": "Characterization of the functional activities of the subunits of 3-deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase from Bacillus subtilis 168.", "content": "Characterization of the functional activities of the subunits of 3-deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase from Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210506"} {"pmid": "4210508", "title": "Induction of chymotrypsinogen by hydrocortisone in embryonic chick pancreas in vitro.", "content": "Induction of chymotrypsinogen by hydrocortisone in embryonic chick pancreas in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210508"} {"pmid": "4210509", "title": "Diazepam inhibition of post-tetanic potentiation in bullfrog sympathetic ganglia: possible role of prostaglandins.", "content": "Diazepam inhibition of post-tetanic potentiation in bullfrog sympathetic ganglia: possible role of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210509"} {"pmid": "4210510", "title": "The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols.", "content": "The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210510"} {"pmid": "4210511", "title": "Small-intestinal bacterial flora in dermatitis herpetiformis.", "content": "Small-intestinal bacterial flora in dermatitis herpetiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210511"} {"pmid": "4210513", "title": "Multilaboratory comparison of three immunodiffusion methods used for the detection of precipitating antibodies in hypersensitivity pneumonitis.", "content": "Multilaboratory comparison of three immunodiffusion methods used for the detection of precipitating antibodies in hypersensitivity pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210513"} {"pmid": "4210512", "title": "The role of vitreous collagen in platelet aggregation in vitro and in vivo.", "content": "The role of vitreous collagen in platelet aggregation in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210512"} {"pmid": "4210514", "title": "Antianginal effects of chromonar. A combined investigation.", "content": "Antianginal effects of chromonar. A combined investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210514"} {"pmid": "4210515", "title": "Pharmacokinetics of pivampicillin and ampicillin in man.", "content": "Pharmacokinetics of pivampicillin and ampicillin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210515"} {"pmid": "4210516", "title": "Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model.", "content": "Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210516"} {"pmid": "4210517", "title": "Lidocaine disposition kinetics in monkey and man. II. Effects of hemorrhage and sympathomimetic drug administration.", "content": "Lidocaine disposition kinetics in monkey and man. II. Effects of hemorrhage and sympathomimetic drug administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210517"} {"pmid": "4210521", "title": "Biochemical effects of denervation in subhuman primate muscles.", "content": "Biochemical effects of denervation in subhuman primate muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210521"} {"pmid": "4210522", "title": "Paraventricular \"pseudotumor\". A case report.", "content": "Paraventricular \"pseudotumor\". A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210522"} {"pmid": "4210523", "title": "Osteoradionecrosis of the mandible resulting from external megavoltage radiation therapy.", "content": "Osteoradionecrosis of the mandible resulting from external megavoltage radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210523"} {"pmid": "4210524", "title": "Some applications of scintiscanning to radiation therapy.", "content": "Some applications of scintiscanning to radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210524"} {"pmid": "4210525", "title": "From animals to man: metabolic considerations.", "content": "From animals to man: metabolic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210525"} {"pmid": "4210526", "title": "Pharmacodynamic and pharmacokinetic measurements of antitumor agents.", "content": "Pharmacodynamic and pharmacokinetic measurements of antitumor agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210526"} {"pmid": "4210527", "title": "Unusual extraperitoneal lesions of the pelvis.", "content": "Unusual extraperitoneal lesions of the pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210527"} {"pmid": "4210528", "title": "Maintenance of urinary asepsis in subhuman primates during chronic catheter drainage.", "content": "Maintenance of urinary asepsis in subhuman primates during chronic catheter drainage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210528"} {"pmid": "4210529", "title": "Infectious process in the lungs after intranasal challenge of white mice with Rickettsia prowazekii. A histologic immunoluminescent and electron microscopic study.", "content": "Infectious process in the lungs after intranasal challenge of white mice with Rickettsia prowazekii. A histologic immunoluminescent and electron microscopic study. The lungs of white mice given intranasal injections of various amounts of Rickettsia prowazekii were studied. Agent parasitism, mainly in the alveolar epithelium and nonciliated cells of bronchiolar epithelium, underlies the infectious process developing in the lungs. Rickettsiae may lodge in these cells without inducing both local and general alterations or a leukocyte response. After being released from the cells they inhabit, rickettsiae evoke acute exudative inflammation. The inflammation is accompanied by marked circulatory disorders, necrosis of exudate cells and vascular thrombosis, which are induced by toxic products of the agent. Polymorphonuclear leukocytes and macrophages represent the main defense mechanism of a host. They ingest and destroy rickettsial organisms. If infection runs a favorable course, phagocytes destroy the rickettsiae, and the organisms are entirely cleared from the lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210529"} {"pmid": "4210518", "title": "A perspective of Soviet blood banking.", "content": "A perspective of Soviet blood banking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210518"} {"pmid": "4210520", "title": "Hepatitis B virus subtypes ad and ay among blood donors in the Greater Los Angeles area.", "content": "Hepatitis B virus subtypes ad and ay among blood donors in the Greater Los Angeles area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210520"} {"pmid": "4210519", "title": "The relation between response to hypotonic stress and the 51Cr recovery in vivo of preserved platelets.", "content": "The relation between response to hypotonic stress and the 51Cr recovery in vivo of preserved platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210519"} {"pmid": "4210538", "title": "Associations between coronary mortality and the weather, Chicago, 1967.", "content": "Associations between coronary mortality and the weather, Chicago, 1967.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210538"} {"pmid": "4210549", "title": "Significance of serum fungal inhibitory factor in dermatophytosis.", "content": "Significance of serum fungal inhibitory factor in dermatophytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210549"} {"pmid": "4210537", "title": "Impact of Medicaid and an OEO health center on use of dental services in an urban area.", "content": "Impact of Medicaid and an OEO health center on use of dental services in an urban area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210537"} {"pmid": "4210550", "title": "Effects of prostaglandins on the internal and external carotid blood flow in the monkey.", "content": "Effects of prostaglandins on the internal and external carotid blood flow in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210550"} {"pmid": "4210553", "title": "Letter: Central venous catheter maintenance.", "content": "Letter: Central venous catheter maintenance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210553"} {"pmid": "4210551", "title": "Proteolysis of preformed protein in wound nutrition.", "content": "Proteolysis of preformed protein in wound nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210551"} {"pmid": "4210552", "title": "Effect of complete parenteral nutrition including fat emulsion on plasma lipid.", "content": "Effect of complete parenteral nutrition including fat emulsion on plasma lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210552"} {"pmid": "4210539", "title": "An exploratory study of associate degree programs for mental health workers.", "content": "An exploratory study of associate degree programs for mental health workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210539"} {"pmid": "4210554", "title": "Parenteral hyperalimentation.", "content": "Parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210554"} {"pmid": "4210555", "title": "Letter: The use of nebulized Intal in asthma.", "content": "Letter: The use of nebulized Intal in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210555"} {"pmid": "4210541", "title": "Influence of postpartum home visits on postpartum clinic attendance.", "content": "Influence of postpartum home visits on postpartum clinic attendance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210541"} {"pmid": "4210544", "title": "Medical costs and other aspects of dog bites in Baltimore.", "content": "Medical costs and other aspects of dog bites in Baltimore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210544"} {"pmid": "4210542", "title": "Supplying health care to nondelegates during 1972 national political conventions.", "content": "Supplying health care to nondelegates during 1972 national political conventions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210542"} {"pmid": "4210559", "title": "The day hospitals organisation: the first 4 years.", "content": "The day hospitals organisation: the first 4 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210559"} {"pmid": "4210560", "title": "The auditory system of the medulla and localization.", "content": "The auditory system of the medulla and localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210560"} {"pmid": "4210561", "title": "Neurophysiological mechanisms of sound localization.", "content": "Neurophysiological mechanisms of sound localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210561"} {"pmid": "4210546", "title": "Irregular reporting of tuberculosis cases by laboratories in Nassau County, N.Y.", "content": "Irregular reporting of tuberculosis cases by laboratories in Nassau County, N.Y.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210546"} {"pmid": "4210562", "title": "Development of some mechanisms useful in sound localization.", "content": "Development of some mechanisms useful in sound localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210562"} {"pmid": "4210564", "title": "Living with long-term home dialysis.", "content": "Living with long-term home dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210564"} {"pmid": "4210565", "title": "Glomerulitis in typhoid fever.", "content": "Glomerulitis in typhoid fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210565"} {"pmid": "4210566", "title": "Ethambutol in pregnancy: observations on embryogenesis.", "content": "Ethambutol in pregnancy: observations on embryogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210566"} {"pmid": "4210567", "title": "Pulmonary allergic granulomatosis: a possible drug reaction in a patient receiving cromolyn sodium.", "content": "Pulmonary allergic granulomatosis: a possible drug reaction in a patient receiving cromolyn sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210567"} {"pmid": "4210568", "title": "The use of total-body counters for the study of iron metabolism and iron loss.", "content": "The use of total-body counters for the study of iron metabolism and iron loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210568"} {"pmid": "4210570", "title": "Treatment of advanced tumours of head and neck with fast neutrons.", "content": "Treatment of advanced tumours of head and neck with fast neutrons. Fast neutrons interact with matter in a different way from x and gamma rays. They have been used at Hammersmith Hospital for the past four years in the treatment of advanced tumours in several sites of the body, and the results of this treatment in the first 100 cases of tumours of the head and neck are described here. Altogether 62 patients who had been referred for fast neutron therapy because it was thought that no other treatment would be effective experienced complete regression of the tumours, and only two recurred. Tumours of the buccal cavity and salivary glands responded particularly well and the relief of pain and ulceration was striking. Side effects were not serious and did not differ from those seen with supervoltage radiation, apart from the reaction of the skin. Follow-up was short, however, owing to deaths from metastases, and out of 76 patients treated more than one year previously only 30 survived. Cases which have not metastasized must therefore be treated so that the effects on tumours and adjacent normal tissues can be observed for several years after treatment. The results obtained so far indicate that it is now justifiable to use neutrons in such cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210570"} {"pmid": "4210571", "title": "Letter: Maternal blood group A and pre-eclampsia.", "content": "Letter: Maternal blood group A and pre-eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210571"} {"pmid": "4210572", "title": "Red cell zinc and red cell zinc metalloenzymes in hyperthyroidism.", "content": "Red cell zinc and red cell zinc metalloenzymes in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210572"} {"pmid": "4210573", "title": "Pituitary-thyroid function after total adrenalectomy in patients with Cushing's disease.", "content": "Pituitary-thyroid function after total adrenalectomy in patients with Cushing's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210573"} {"pmid": "4210574", "title": "Phenolic metabolites of DL-norgestrel: a method for the removal of 1-hydroxylated metabolites, potential sources of phenolic artifacts.", "content": "Phenolic metabolites of DL-norgestrel: a method for the removal of 1-hydroxylated metabolites, potential sources of phenolic artifacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210574"} {"pmid": "4210575", "title": "Electron microscopy of gonococci in the urethral secretions of patients with gonorrhoea treated with penicillin and erythromycin.", "content": "Electron microscopy of gonococci in the urethral secretions of patients with gonorrhoea treated with penicillin and erythromycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210575"} {"pmid": "4210576", "title": "Immunofluorescence staining for the detection of Neisseria gonorrhoeae in women.", "content": "Immunofluorescence staining for the detection of Neisseria gonorrhoeae in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210576"} {"pmid": "4210577", "title": "Modified transport and growth medium for the cultivation of Neisseria gonorrhoeae.", "content": "Modified transport and growth medium for the cultivation of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210577"} {"pmid": "4210578", "title": "Sensitivity to ampicillin, penicillin, and tetracyline of gonococci in Rotterdam.", "content": "Sensitivity to ampicillin, penicillin, and tetracyline of gonococci in Rotterdam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210578"} {"pmid": "4210579", "title": "Growth and effect of mycoplasmas in Fallopian tube organ cultures.", "content": "Growth and effect of mycoplasmas in Fallopian tube organ cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210579"} {"pmid": "4210580", "title": "Sexually-transmitted diseases in women.", "content": "Sexually-transmitted diseases in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210580"} {"pmid": "4210581", "title": "An approach to VD control based on a study in Kingston, Jamaica.", "content": "An approach to VD control based on a study in Kingston, Jamaica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210581"} {"pmid": "4210582", "title": "Hepatitis B antigen in prostitutes.", "content": "Hepatitis B antigen in prostitutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210582"} {"pmid": "4210583", "title": "Letter: Puerperal rubella vaccination and anti-D immunoglobulin.", "content": "Letter: Puerperal rubella vaccination and anti-D immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210583"} {"pmid": "4210584", "title": "Phospholipids in amniotic fluid. I. Relationship of phospholipid concentrations to gestation, maternal disease and fetal outcome.", "content": "Phospholipids in amniotic fluid. I. Relationship of phospholipid concentrations to gestation, maternal disease and fetal outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210584"} {"pmid": "4210586", "title": "The metabolism of (75Se)selenite in young women.", "content": "The metabolism of (75Se)selenite in young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210586"} {"pmid": "4210585", "title": "The metabolism of 14C-labelled essential amino acids given by intragastric or intravenous infusion to rats on normal and protein-free diets.", "content": "The metabolism of 14C-labelled essential amino acids given by intragastric or intravenous infusion to rats on normal and protein-free diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210585"} {"pmid": "4210587", "title": "The utilization of gelled maize starch in the small intestine of sheep.", "content": "The utilization of gelled maize starch in the small intestine of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210587"} {"pmid": "4210588", "title": "Plasma fibrinogen and its fragments during streptokinase treatment.", "content": "Plasma fibrinogen and its fragments during streptokinase treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210588"} {"pmid": "4210589", "title": "Pilus-dependence of four Pseudomonas aeruginosa bacteriophages with non-contractile tails.", "content": "Pilus-dependence of four Pseudomonas aeruginosa bacteriophages with non-contractile tails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210589"} {"pmid": "4210590", "title": "Integrity of cell-bound poly(I).poly(C).", "content": "Integrity of cell-bound poly(I).poly(C).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210590"} {"pmid": "4210591", "title": "Modifications by sodium auro-thio-malate of the expression of virulence in mice by defined strains of Semliki Forest virus.", "content": "Modifications by sodium auro-thio-malate of the expression of virulence in mice by defined strains of Semliki Forest virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210591"} {"pmid": "4210593", "title": "Screening for gonorrhea in a low-risk population.", "content": "Screening for gonorrhea in a low-risk population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210593"} {"pmid": "4210592", "title": "Amniotic fluid glucose concentration.", "content": "Amniotic fluid glucose concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210592"} {"pmid": "4210594", "title": "Studies on uterine flushings in the baboon. 3. Immunochemical composition in animals with and without intrauterine contraceptive devices.", "content": "Studies on uterine flushings in the baboon. 3. Immunochemical composition in animals with and without intrauterine contraceptive devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210594"} {"pmid": "4210595", "title": "Enhancement of the IgG antibody production to Escherichia coli O antigen by prior exposure to serologically different E. coli bacteria.", "content": "Enhancement of the IgG antibody production to Escherichia coli O antigen by prior exposure to serologically different E. coli bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210595"} {"pmid": "4210596", "title": "Transient antigen-specific non-reactivity of an organ induced in sensitized animals by repeated challenges. A new experimental phenomenon observed in the parotid gland of rats.", "content": "Transient antigen-specific non-reactivity of an organ induced in sensitized animals by repeated challenges. A new experimental phenomenon observed in the parotid gland of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210596"} {"pmid": "4210597", "title": "Osteoclastic resorption of 3H-proline labelled bone, dentine and cementum in the rat.", "content": "Osteoclastic resorption of 3H-proline labelled bone, dentine and cementum in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210597"} {"pmid": "4210598", "title": "Genetic control of spermiogenesis in Drosophila melanogaster: the effects of abnormal cytoplasmic microtubule populations in mutant ms(3)10R and its colcemid-induced phenocopy.", "content": "Genetic control of spermiogenesis in Drosophila melanogaster: the effects of abnormal cytoplasmic microtubule populations in mutant ms(3)10R and its colcemid-induced phenocopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210598"} {"pmid": "4210599", "title": "Dynamics of spermiogenesis in Drosophila melanogaster. IV. Nuclear transformation.", "content": "Dynamics of spermiogenesis in Drosophila melanogaster. IV. Nuclear transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210599"} {"pmid": "4210600", "title": "Chemical modification of mushroom tyrosinase for stabilization to reaction inactivation.", "content": "Chemical modification of mushroom tyrosinase for stabilization to reaction inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210600"} {"pmid": "4210601", "title": "Seeing form.", "content": "Seeing form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210601"} {"pmid": "4210602", "title": "Brain damage and seeing: a new look at some old problems.", "content": "Brain damage and seeing: a new look at some old problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210602"} {"pmid": "4210603", "title": "The argon laser-the effect on retinal tissues and its clinical applications.", "content": "The argon laser-the effect on retinal tissues and its clinical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210603"} {"pmid": "4210604", "title": "Vortex patterns of the corneal epithelium.", "content": "Vortex patterns of the corneal epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210604"} {"pmid": "4210605", "title": "Ocular brucellosis.", "content": "Ocular brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210605"} {"pmid": "4210606", "title": "Myocardial changes in monkeys fed mustard oil.", "content": "Myocardial changes in monkeys fed mustard oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210606"} {"pmid": "4210608", "title": "Long-term results of carotid artery surgery for cerebrovascular insufficiency.", "content": "Long-term results of carotid artery surgery for cerebrovascular insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210608"} {"pmid": "4210609", "title": "Antibiotic susceptibility of gram-negative bacilli isolated from blood cultures. Results of tests with 35 agents and strains from 169 patients at Boston City Hospital during 1972.", "content": "Antibiotic susceptibility of gram-negative bacilli isolated from blood cultures. Results of tests with 35 agents and strains from 169 patients at Boston City Hospital during 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210609"} {"pmid": "4210620", "title": "Cell fusion induced by Germiston and Wesselsbron viruses.", "content": "Cell fusion induced by Germiston and Wesselsbron viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210620"} {"pmid": "4210619", "title": "Parenteral hyperalimentation.", "content": "Parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210619"} {"pmid": "4210622", "title": "Therapeutic intravenous alimentation for traumatic chylous ascites in a child.", "content": "Therapeutic intravenous alimentation for traumatic chylous ascites in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210622"} {"pmid": "4210621", "title": "Jaundice, hypertrophic pyloric stenosis, and hepatic glucuronyl transferase.", "content": "Jaundice, hypertrophic pyloric stenosis, and hepatic glucuronyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210621"} {"pmid": "4210636", "title": "Human and bovine prothrombin similarities.", "content": "Human and bovine prothrombin similarities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210636"} {"pmid": "4210637", "title": "Power spectra of pulse sequences and implications for membrane fluctuations.", "content": "Power spectra of pulse sequences and implications for membrane fluctuations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210637"} {"pmid": "4210638", "title": "A stochastic model for chemical kinetics.", "content": "A stochastic model for chemical kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210638"} {"pmid": "4210665", "title": "Projections from the pulvinar to the middle temporal visual area (MT) in the owl monkey, Aotus trivirgatus.", "content": "Projections from the pulvinar to the middle temporal visual area (MT) in the owl monkey, Aotus trivirgatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210665"} {"pmid": "4210664", "title": "Demonstration of detergent-soluble antigen specific for the synaptosomal membrane-fraction isolated from the cat cerebral cortex.", "content": "Demonstration of detergent-soluble antigen specific for the synaptosomal membrane-fraction isolated from the cat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210664"} {"pmid": "4210679", "title": "Electrophysiological analysis of the effects of L-dopa on the reciprocal corticothalamic projections in the squirrel monkey. I. Iatrogenic coma and disinhibition of medial thalamic neurons.", "content": "Electrophysiological analysis of the effects of L-dopa on the reciprocal corticothalamic projections in the squirrel monkey. I. Iatrogenic coma and disinhibition of medial thalamic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210679"} {"pmid": "4210680", "title": "Control of stable RNA synthesis in a temperature-sensitive mutant of elongation factor G of Bacillus subtilis.", "content": "Control of stable RNA synthesis in a temperature-sensitive mutant of elongation factor G of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210680"} {"pmid": "4210681", "title": "Dark repair of DNA containing \"spore photoproduct\" in Bacillus subtilis.", "content": "Dark repair of DNA containing \"spore photoproduct\" in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210681"} {"pmid": "4210683", "title": "Effect of supratentorial space-occupying lesions on regional intracranial pressure and local cerebral blood flow: an experimental study in baboons.", "content": "Effect of supratentorial space-occupying lesions on regional intracranial pressure and local cerebral blood flow: an experimental study in baboons. Cortical blood flow and epidural intracranial pressure have been measured in the two supratentorial compartments of the intracranial space in experimental baboons during the acute expansion of a parieto-occipital epidural balloon. Differential pressures between the two halves of the supratentorial space have been found, and these have been associated with evidence that flow has fallen more quickly in the hemisphere most compressed. The evidence points to a more rapid exhaustion of the autoregulatory capacity in the hemisphere subjected to greater compression, a fall in perfusion pressure to below critical autoregulatory levels occurring slightly before that in the opposite hemisphere, and the establishment of a differential flow pattern for a short time during a critical phase of compression. The displacements induced by inflation of the parieto-occipital balloon have been described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210683"} {"pmid": "4210682", "title": "Inactivation of 6-phosphogluconate dehydrogenase structural gene of Drosophila melanogaster caused by translocation to heterochromatin.", "content": "Inactivation of 6-phosphogluconate dehydrogenase structural gene of Drosophila melanogaster caused by translocation to heterochromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210682"} {"pmid": "4210684", "title": "Tuberculous meningitis as a complication of sarcoidosis.", "content": "Tuberculous meningitis as a complication of sarcoidosis. In two patients with well established sarcoidosis, the acute onset of meningitis proved to be due to tuberculosis rather than to an extension of sarcoid granulomata to the meninges. The cerebrospinal fluid changes are very similar, and the differential diagnosis rests on a search for Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210684"} {"pmid": "4210685", "title": "Muscle blood flow in Duchenne type muscular dystrophy, limb-girdle dystrophy, polymyositis, and in normal controls.", "content": "Muscle blood flow in Duchenne type muscular dystrophy, limb-girdle dystrophy, polymyositis, and in normal controls. Muscle blood flow (MBF) was measured using the local (133)Xenon injection method in patients with Duchenne type muscular dystrophy (six), limb-girdle dystrophy (four), polymyositis (seven), and in normal controls (11). Measurements were made at rest and during hyperaemia induced by ischaemic exercise and by histamine injection. Capillary diffusion capacity was measured with the (51)Cr-EDTA method in three patients with Duchenne dystrophy and in six normal controls. Patients with Duchenne dystrophy had normal MBF during rest and during hyperaemia after exercise and significantly increased MBF after histamine injection. The capillary diffusion capacity was higher than normal, but not significantly. In limb-girdle dystrophy MBF was normal, while in polymyositis it was significantly decreased in all three circulatory states. The relevance of the findings to the proposed ischaemic aetiology of Duchenne dystrophy is considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210685"} {"pmid": "4210686", "title": "Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man.", "content": "Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man. Concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were significantly higher in CSF obtained after injection of air during pneumoencephalography (PEG) than in lumbar CSF, as drawn before the injection. There was a high correlation between levels in the `mixed' and lumbar samples of CSF in the case of each of the two acids. The concentration of lumbar HVA, but not that of 5-HIAA, was negatively correlated with CSF pressure. 5-HIAA levels were low in both samples of CSF in a group of epileptics, by comparison with controls. In two patients with Kufs disease and in one with Niemann-Pick disease, the concentration of HVA was very low in the lumbar sample. The application of a standardized PEG technique in the study of monoamine metabolism in man is suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210686"} {"pmid": "4210687", "title": "Two cases of hepatic mastocytoma in sheep.", "content": "Two cases of hepatic mastocytoma in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210687"} {"pmid": "4210688", "title": "Giant cell aortitis in a South American monkey (Callimico goeldii).", "content": "Giant cell aortitis in a South American monkey (Callimico goeldii).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210688"} {"pmid": "4210689", "title": "Endometriosis in four irradiated rhesus monkeys.", "content": "Endometriosis in four irradiated rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210689"} {"pmid": "4210691", "title": "Letter: Osteitis deformans in a macaque.", "content": "Letter: Osteitis deformans in a macaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210691"} {"pmid": "4210690", "title": "Chronic eosinophilic myositis in a rhesus monkey infected with sarcosporidiosis.", "content": "Chronic eosinophilic myositis in a rhesus monkey infected with sarcosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210690"} {"pmid": "4210697", "title": "A new genus of late oligocene monkey (Cebidae, Platyrrhini) with notes on postorbital closure and Platyrrhine evolution.", "content": "A new genus of late oligocene monkey (Cebidae, Platyrrhini) with notes on postorbital closure and Platyrrhine evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210697"} {"pmid": "4210698", "title": "Ecological relations and niche separation between sympatric terrestrial primates in Ethiopia.", "content": "Ecological relations and niche separation between sympatric terrestrial primates in Ethiopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210698"} {"pmid": "4210699", "title": "A ten-year summary of reproductive data for free-ranging Macaca mulatta.", "content": "A ten-year summary of reproductive data for free-ranging Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210699"} {"pmid": "4210700", "title": "Nucleus ventroposterior inferior (VPI) as the ventibular thalamic relay in the rhesus monkey. I. Field potential investigation.", "content": "Nucleus ventroposterior inferior (VPI) as the ventibular thalamic relay in the rhesus monkey. I. Field potential investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210700"} {"pmid": "4210701", "title": "Complement-induced changes in the core structure of sheep erythrocyte membranes: a study by freeze-etch electron microscopy.", "content": "Complement-induced changes in the core structure of sheep erythrocyte membranes: a study by freeze-etch electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210701"} {"pmid": "4210703", "title": "Purification and kinetic mechanism of rat liver glycogen synthase.", "content": "Purification and kinetic mechanism of rat liver glycogen synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210703"} {"pmid": "4210702", "title": "Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria.", "content": "Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210702"} {"pmid": "4210704", "title": "Phasic myocardial blood content. An experimental study on effects of hypoxaemia, ischaemia and coronary drugs.", "content": "Phasic myocardial blood content. An experimental study on effects of hypoxaemia, ischaemia and coronary drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210704"} {"pmid": "4210705", "title": "Hematology of laboratory baboons in Kenya.", "content": "Hematology of laboratory baboons in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210705"} {"pmid": "4210706", "title": "Chromosome banding patterns in squirrel monkeys (Saimiri sciureus).", "content": "Chromosome banding patterns in squirrel monkeys (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210706"} {"pmid": "4210708", "title": "Serum thyrotropin during daily life and in response to thyrotropin releasing hormone in normal subjects and juvenile diabetics.", "content": "Serum thyrotropin during daily life and in response to thyrotropin releasing hormone in normal subjects and juvenile diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210708"} {"pmid": "4210707", "title": "Comparative metabolism of drugs in man and monkeys.", "content": "Comparative metabolism of drugs in man and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210707"} {"pmid": "4210709", "title": "Relationship between plasma corticosterone and the development of ketoacidosis in the alloxan diabetic rat.", "content": "Relationship between plasma corticosterone and the development of ketoacidosis in the alloxan diabetic rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210709"} {"pmid": "4210711", "title": "FSA-foetal sulphoglycoprotein antigen associated with gastric cancer.", "content": "FSA-foetal sulphoglycoprotein antigen associated with gastric cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210711"} {"pmid": "4210726", "title": "Comparative sensitivity of gel-diffusion and tube agglutination tests for the detection of Brucella canis antibodies in experimentally infected dogs.", "content": "Comparative sensitivity of gel-diffusion and tube agglutination tests for the detection of Brucella canis antibodies in experimentally infected dogs. The microslide gel-diffusion and macro-tube agglutination techniques to detect Brucella canis antibodies in dogs were compared. Sera from dogs experimentally infected with B. canis and a random sample of dog sera with unknown histories of exposure to this organism were examined. The results of the gel-diffusion method employing specific rough Brucella saline-extract antigens of B. canis and Brucella ovis were comparable to those obtained by the tube agglutination test. The easily prepared, stable R antigen in the freeze-dried form offers a convenient, simple, and reliable diagnostic method for the serological detection of canine brucellosis by the gel-diffusion test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210726"} {"pmid": "4210728", "title": "Development of a defined minimal medium for the growth of Neisseria gonorrhoeae.", "content": "Development of a defined minimal medium for the growth of Neisseria gonorrhoeae. This investigation describes the development of a solid and a liquid medium (Gonococcal Genetic Medium; GGM) which support the rapid growth of 41 gonococcal clinical isolates and laboratory strains with a minimum number of nutritional components. The complete medium contains minimal salts, eight amino acids, two nitrogen bases, vitamins, coenzymes, key metabolic intermediates, and some miscellaneous components. Results indicate that GGM can be modified and simplified even further than we described. In liquid GGM, several gonococcal strains grew logarithmically after a 2- to 3-h lag period with generation times ranging from 72 to 115 min, reaching optical densities of 175 to 320 Klett units in the presence of seven amino acids and in the absence of a CO(2) atmosphere. The development of a solid and a liquid defined minimal medium such as GGM should greatly broaden the avenues of experimentation for biochemical genetic studies with N. gonorrhoeae, especially gonococcal genetic transformation. N. gonorrhoeae can be classified into eight major and minor phenotypic groups, depending on its growth responses on GGM to just five amino acids: cysteine and cystine, arginine, proline, isoleucine, and serine. Such results demonstrate the feasibility of using GGM as a simple, sensitive, rapid probe for investigating the epidemiological patterns of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210728"} {"pmid": "4210727", "title": "Simple, inexpensive procedure for the disruption of bacteria.", "content": "Simple, inexpensive procedure for the disruption of bacteria. Small volumes (1 to 2 ml) of bacterial cultures, with turbidities ranging from 3 to 10, were disrupted 50 to 90% (measured as a decrease in turbidity) within 2 min, by shaking them on a Vortex-type mixer in the presence of glass beads. This method of disrupton was effective for cells in the following genera: Streptococcus, Lactobacillus, Staphylococcus, Bacillus, and Escherichia. After low-speed centrifugation, the resulting extract can be used as potential sources for enzymes, transforming deoxyribonucleic acids, cell walls, membranes, etc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210727"} {"pmid": "4210729", "title": "Use of sodium polyanethol sulfonate in the preparation of 5 per cent sheep blood agar plates.", "content": "Use of sodium polyanethol sulfonate in the preparation of 5 per cent sheep blood agar plates. An alternative method to defibrinating sheep blood for use in bacteriological media is described. The new procedure incorporates sodium polyanethol sulfonate in a concentration of 0.05% (vol/vol). In testing 117 bacterial and fungal isolates, no significant differences were found with respect to adequate growth, pigment production, hemolytic reactions, and other physical attributes. Further tests demonstrate that the sodium polyanethol sulfonate in sheep blood agar plates does not cause any aberrations in zone sizes around disks used in antibiotic susceptibility tests. Consequently, the method represents a suitable alternative to the use of defibrinated sheep blood in the preparation of bacteriological media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210729"} {"pmid": "4210730", "title": "Characterization of the precipitin bands detected in the immunodiffusion test for paracoccidioidomycosis.", "content": "Characterization of the precipitin bands detected in the immunodiffusion test for paracoccidioidomycosis. In order to characterize the precipitin bands detected in the immunodiffusion test for paracoccidioidomycosis, a study was undertaken in 54 patients with the disease. On the basis of the pattern of known control sera, the three commonly observed lines of precipitate were designated as 1, 2, and 3 according to their location in the immunodiffusion plate. At time of diagnosis, 28 of the patients exhibited all three bands, 16 gave two bands, and 10 showed only one precipitin line. Over 50 of the sera with three bands had high complement fixation titers (above 1:512), whereas those with one band exhibited lower titers. A similar picture was obtained with the quantitative agar-gel techniques, where titers of 1:64 and above were more commonly observed in sera with three precipitin lines. Follow-up studies carried out in 18 patients revealed that band 3 disappeared first, followed by band 2, and, finally, by band 1. At the end of 2 to 3 years, 85.7% of the patients had lost band 3, 75% band 2, and only 27.7% band 1. Cross-reactions with histoplasmin were found in eight patients who gave the M precipitin line with this antigen. It was found that the latter band and our paracoccidioidin band 3 fused, producing lines of identity. Bands 1 and 2 were specific. The implications of these findings are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210730"} {"pmid": "4210732", "title": "Antibiotics excreted into the bile--action on the tone and motility of the bile duct.", "content": "Antibiotics excreted into the bile--action on the tone and motility of the bile duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210732"} {"pmid": "4210751", "title": "Purification and some properties of streptolysin O.", "content": "Purification and some properties of streptolysin O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210751"} {"pmid": "4210754", "title": "Intravenous hyperalimentation for the onco-surgical patient.", "content": "Intravenous hyperalimentation for the onco-surgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210754"} {"pmid": "4210756", "title": "Rapid assay of proteolytic enzymes on film material.", "content": "Rapid assay of proteolytic enzymes on film material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210756"} {"pmid": "4210757", "title": "The diagnostic significance of anginal symptoms.", "content": "The diagnostic significance of anginal symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210757"} {"pmid": "4210758", "title": "Dilution curves studies in coumarin plasma and in artificially depleted abnormal control plasmas.", "content": "Dilution curves studies in coumarin plasma and in artificially depleted abnormal control plasmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210758"} {"pmid": "4210759", "title": "Some observations on the fine structure of the epidermal-dermal junction in the skin of the frog tadpole, Rana rugosa.", "content": "Some observations on the fine structure of the epidermal-dermal junction in the skin of the frog tadpole, Rana rugosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210759"} {"pmid": "4210760", "title": "Tuberculosis in mink.", "content": "Tuberculosis in mink.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210760"} {"pmid": "4210762", "title": "The organization of the second visual area (V II) in the owl monkey: a second order transformation of the visual hemifield.", "content": "The organization of the second visual area (V II) in the owl monkey: a second order transformation of the visual hemifield.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210762"} {"pmid": "4210761", "title": "Iron absorption after splenectomy in hereditary spherocytosis.", "content": "Iron absorption after splenectomy in hereditary spherocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210761"} {"pmid": "4210763", "title": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Influence of exogenous low-level currents. Are weak oscillating fields detected by the brain?", "content": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Influence of exogenous low-level currents. Are weak oscillating fields detected by the brain?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210763"} {"pmid": "4210764", "title": "Survival of Listeria monocytogenes in soil and water.", "content": "Survival of Listeria monocytogenes in soil and water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210764"} {"pmid": "4210765", "title": "A survey for sarcosporidial cysts in east African game animals.", "content": "A survey for sarcosporidial cysts in east African game animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210765"} {"pmid": "4210766", "title": "A note on the blood parasites of some birds from the Republic of Madagascar.", "content": "A note on the blood parasites of some birds from the Republic of Madagascar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210766"} {"pmid": "4210767", "title": "Parasites of the tide pool fish Liparis atlanticus (Osteichthyes:Liparidae).", "content": "Parasites of the tide pool fish Liparis atlanticus (Osteichthyes:Liparidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210767"} {"pmid": "4210768", "title": "Indications of a viral etiology for marble spleen disease in pheasants.", "content": "Indications of a viral etiology for marble spleen disease in pheasants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210768"} {"pmid": "4210769", "title": "Isolation of viruses from wild mammals in West Africa, 1966-1970.", "content": "Isolation of viruses from wild mammals in West Africa, 1966-1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210769"} {"pmid": "4210772", "title": "Acidic fraction of ribosomal proteins from Lactobacillus acidophilus.", "content": "Acidic fraction of ribosomal proteins from Lactobacillus acidophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210772"} {"pmid": "4210771", "title": "The distribution and character of glomerular deposits in systemic lupus erythematosus.", "content": "The distribution and character of glomerular deposits in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210771"} {"pmid": "4210774", "title": "The negatively charged protein extracted from Tetrahymena pyriformis as an attractant in Amoeba proteus chemotaxis.", "content": "The negatively charged protein extracted from Tetrahymena pyriformis as an attractant in Amoeba proteus chemotaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210774"} {"pmid": "4210773", "title": "Localization of intracellular antigens by immunoelectron microscopy.", "content": "Localization of intracellular antigens by immunoelectron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210773"} {"pmid": "4210775", "title": "Further studies on the factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro.", "content": "Further studies on the factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210775"} {"pmid": "4210776", "title": "Method for the analysis of tRNA patterns in Drosophila melanogaster using an amino acid analyser.", "content": "Method for the analysis of tRNA patterns in Drosophila melanogaster using an amino acid analyser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210776"} {"pmid": "4210778", "title": "Somple flow-cell for the fluorimetric study of conformational changes of proteins on agarose matrix.", "content": "Somple flow-cell for the fluorimetric study of conformational changes of proteins on agarose matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210778"} {"pmid": "4210777", "title": "A scanning dual wavelength spectrophotometer: application to the study of photosynthetic electron transport.", "content": "A scanning dual wavelength spectrophotometer: application to the study of photosynthetic electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210777"} {"pmid": "4210779", "title": "Radioimmunoassays of 3,4,5-trimethoxyphenethylamine (mescaline) and 2,5-dimethoxy-4-methylphenyl-isopropylamine(DOM).", "content": "Radioimmunoassays of 3,4,5-trimethoxyphenethylamine (mescaline) and 2,5-dimethoxy-4-methylphenyl-isopropylamine(DOM).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210779"} {"pmid": "4210781", "title": "Effect of brinolase on lens extraction in cynomolgus monkeys (Macaca fascicularis). A double blind study.", "content": "Effect of brinolase on lens extraction in cynomolgus monkeys (Macaca fascicularis). A double blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210781"} {"pmid": "4210780", "title": "Analysis of polypeptide molecular weights by electrophoresis in urea.", "content": "Analysis of polypeptide molecular weights by electrophoresis in urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210780"} {"pmid": "4210782", "title": "Brinolase for lens extractopm in cynomolgus monkey (Macaca fascicularis). A toxicity study.", "content": "Brinolase for lens extractopm in cynomolgus monkey (Macaca fascicularis). A toxicity study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210782"} {"pmid": "4210796", "title": "Schwann cells and perineurium in neuroma. Some morphological aspects.", "content": "Schwann cells and perineurium in neuroma. Some morphological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210796"} {"pmid": "4210795", "title": "Reversed-phase liquid chromatography of some pesticides and related compounds. Solubility-retention relationships.", "content": "Reversed-phase liquid chromatography of some pesticides and related compounds. Solubility-retention relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210795"} {"pmid": "4210797", "title": "Distribution of goldthioglucose in mice with and without experimental allergic encephalomyelitis.", "content": "Distribution of goldthioglucose in mice with and without experimental allergic encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210797"} {"pmid": "4210798", "title": "Ultrastructural reorganization, DNA synthesis and mitotic division of myocytes in atria of rats with left ventricle infarction. An electron microscopic and autoradiographic study.", "content": "Ultrastructural reorganization, DNA synthesis and mitotic division of myocytes in atria of rats with left ventricle infarction. An electron microscopic and autoradiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210798"} {"pmid": "4210799", "title": "Trisomy for short arm of chromosome 20.", "content": "Trisomy for short arm of chromosome 20.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210799"} {"pmid": "4210800", "title": "The pharyngeal hypophysis in some laboratory animals.", "content": "The pharyngeal hypophysis in some laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210800"} {"pmid": "4210803", "title": "The natural history of endogenous skin malignancy as a basis for experimental research.", "content": "The natural history of endogenous skin malignancy as a basis for experimental research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210803"} {"pmid": "4210810", "title": "WHO Expert Committee on Malaria: sixteenth report.", "content": "WHO Expert Committee on Malaria: sixteenth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210810"} {"pmid": "4210812", "title": "Polyribosomes associated with the Golgi apparatus.", "content": "Polyribosomes associated with the Golgi apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210812"} {"pmid": "4210814", "title": "Typing of Pseudomonas aeruginosa.", "content": "Typing of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210814"} {"pmid": "4210813", "title": "The influence of juvenile hormone on the plasma membrane of symbiotic bacteria.", "content": "The influence of juvenile hormone on the plasma membrane of symbiotic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210813"} {"pmid": "4210821", "title": "Frustration and self-aggression in social isolate rhesus monkeys.", "content": "Frustration and self-aggression in social isolate rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210821"} {"pmid": "4210824", "title": "Studies in partially-treated and chronic gonococcal urethritis.", "content": "Studies in partially-treated and chronic gonococcal urethritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210824"} {"pmid": "4210825", "title": "Protein-calorie malnutrition in West African children.", "content": "Protein-calorie malnutrition in West African children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210825"} {"pmid": "4210826", "title": "Magnesium deficiency.", "content": "Magnesium deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210826"} {"pmid": "4210827", "title": "Clinico-electroencephalographic study of epilepsy after head injury.", "content": "Clinico-electroencephalographic study of epilepsy after head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210827"} {"pmid": "4210828", "title": "Latex agglutination test for invasive amoebiasis.", "content": "Latex agglutination test for invasive amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210828"} {"pmid": "4210819", "title": "Wernicke's encephalopathy in a child with congenital cardiomegaly. 2. Morphological aspects and pathogenetic considerations.", "content": "Wernicke's encephalopathy in a child with congenital cardiomegaly. 2. Morphological aspects and pathogenetic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210819"} {"pmid": "4210831", "title": "The nutrition problem in India.", "content": "The nutrition problem in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210831"} {"pmid": "4210833", "title": "Asthma preventive developed.", "content": "Asthma preventive developed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210833"} {"pmid": "4210839", "title": "Population genetic studies in Nigeria.", "content": "Population genetic studies in Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210839"} {"pmid": "4210841", "title": "Nycthemeral variation in the parasitaemia of Trypanosoma minasense in naturally infected marmosets of the genus Callithrix (primates, Callithricidae).", "content": "Nycthemeral variation in the parasitaemia of Trypanosoma minasense in naturally infected marmosets of the genus Callithrix (primates, Callithricidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210841"} {"pmid": "4210844", "title": "Rhesus non-isoimmunization. A review and case report.", "content": "Rhesus non-isoimmunization. A review and case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210844"} {"pmid": "4210845", "title": "Juvenile hormone and the adult development of Drosophila.", "content": "Juvenile hormone and the adult development of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210845"} {"pmid": "4210846", "title": "The effects of heavy metal ions on the motility of sea urchin spermatozoa.", "content": "The effects of heavy metal ions on the motility of sea urchin spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210846"} {"pmid": "4210848", "title": "A comparison of the absorption of effervescent preparations of paracetamol and penicillin V (phenoxymethylpenicillin) with solid dose forms of these drugs.", "content": "A comparison of the absorption of effervescent preparations of paracetamol and penicillin V (phenoxymethylpenicillin) with solid dose forms of these drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210848"} {"pmid": "4210847", "title": "DMSO: a new respiratory stimulant?", "content": "DMSO: a new respiratory stimulant?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210847"} {"pmid": "4210865", "title": "Radiation enteritis.", "content": "Radiation enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210865"} {"pmid": "4210866", "title": "Intravenous hyperalimentation protocol.", "content": "Intravenous hyperalimentation protocol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210866"} {"pmid": "4210858", "title": "Unproven methods of cancer management. Grape diet.", "content": "Unproven methods of cancer management. Grape diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210858"} {"pmid": "4210868", "title": "Use of cromolyn sodium in childhood asthma.", "content": "Use of cromolyn sodium in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210868"} {"pmid": "4210855", "title": "The role of genetics in human cancer.", "content": "The role of genetics in human cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210855"} {"pmid": "4210856", "title": "Lymphomas--troublesome problems in management.", "content": "Lymphomas--troublesome problems in management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210856"} {"pmid": "4210862", "title": "Alexander Hughes Bennett (1848-1901) and Rickman John Godlee (1849-1925).", "content": "Alexander Hughes Bennett (1848-1901) and Rickman John Godlee (1849-1925).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210862"} {"pmid": "4210859", "title": "Early diagnosis of colorectal cancer.", "content": "Early diagnosis of colorectal cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210859"} {"pmid": "4210857", "title": "Precancerous lesions of the uterine cervix in pregnancy.", "content": "Precancerous lesions of the uterine cervix in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210857"} {"pmid": "4210861", "title": "Malignant scrotal masses in children.", "content": "Malignant scrotal masses in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210861"} {"pmid": "4210860", "title": "Endoscopic examination of the colon and rectum.", "content": "Endoscopic examination of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210860"} {"pmid": "4210864", "title": "Editorial: Cancer nursing--something old, something new.", "content": "Editorial: Cancer nursing--something old, something new.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210864"} {"pmid": "4210877", "title": "Cell interaction in conjugation of ciliates.", "content": "Cell interaction in conjugation of ciliates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210877"} {"pmid": "4210878", "title": "Beta, gamma unsaturated amino acids as irreversible enzyme inhibitors.", "content": "Beta, gamma unsaturated amino acids as irreversible enzyme inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210878"} {"pmid": "4210871", "title": "Metastatic cervical nodes of unknown primary origin.", "content": "Metastatic cervical nodes of unknown primary origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210871"} {"pmid": "4210863", "title": "A case of cerebral tumor--the surgical treatment.", "content": "A case of cerebral tumor--the surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210863"} {"pmid": "4210879", "title": "Chelating agents for the binding of metal ions to macromolecules.", "content": "Chelating agents for the binding of metal ions to macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210879"} {"pmid": "4210880", "title": "Lymphocyte transformation in human Plasmodium falciparum malaria.", "content": "Lymphocyte transformation in human Plasmodium falciparum malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210880"} {"pmid": "4210881", "title": "Recovery from anti-IG induced immunosuppression: implications for a model of Ig-secreting cell development.", "content": "Recovery from anti-IG induced immunosuppression: implications for a model of Ig-secreting cell development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210881"} {"pmid": "4210869", "title": "Human cancer virus vaccines.", "content": "Human cancer virus vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210869"} {"pmid": "4210872", "title": "Evarts A. Graham (1883-1957).", "content": "Evarts A. Graham (1883-1957).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210872"} {"pmid": "4210882", "title": "The role of activated macrophages in specific and nonspecific cytostasis of tumor cells.", "content": "The role of activated macrophages in specific and nonspecific cytostasis of tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210882"} {"pmid": "4210883", "title": "A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement.", "content": "A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210883"} {"pmid": "4210884", "title": "TRIC type K, a new immunologic type of Chlamydia trachomatis.", "content": "TRIC type K, a new immunologic type of Chlamydia trachomatis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210884"} {"pmid": "4210870", "title": "Diagnosis and management of common skin cancers.", "content": "Diagnosis and management of common skin cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210870"} {"pmid": "4210873", "title": "Successful removal of an entire lung for carcinoma of the bronchus.", "content": "Successful removal of an entire lung for carcinoma of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210873"} {"pmid": "4210885", "title": "Distribution of isotypic and allotypic human IgG antigens in non-human primates.", "content": "Distribution of isotypic and allotypic human IgG antigens in non-human primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210885"} {"pmid": "4210886", "title": "Immunoglobulin expression of cells from human lymphoblastoid lines. I. Heavy and light chain antigens of the cell surface.", "content": "Immunoglobulin expression of cells from human lymphoblastoid lines. I. Heavy and light chain antigens of the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210886"} {"pmid": "4210874", "title": "Editorial: A patient's right to die--the easy way out?", "content": "Editorial: A patient's right to die--the easy way out?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210874"} {"pmid": "4210887", "title": "Immunoglobulin expression of cells from human lymphoblastoid lines. II. Interrelationship among surface, cellular, and secreted immunoglobulins.", "content": "Immunoglobulin expression of cells from human lymphoblastoid lines. II. Interrelationship among surface, cellular, and secreted immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210887"} {"pmid": "4210888", "title": "Human lymphocyte membrane immunoglobulin as a reflection of maturation.", "content": "Human lymphocyte membrane immunoglobulin as a reflection of maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210888"} {"pmid": "4210889", "title": "The capping of surface immunoglobulin on mouse myeloma cells.", "content": "The capping of surface immunoglobulin on mouse myeloma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210889"} {"pmid": "4210890", "title": "Specific assay of gentamicin in the presence of penicillins and cephalosporins. Use of commercially manufactured beta-lactamases.", "content": "Specific assay of gentamicin in the presence of penicillins and cephalosporins. Use of commercially manufactured beta-lactamases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210890"} {"pmid": "4210891", "title": "Studies of the formation of a violet-reddish pigment from the cephalosporin derivative celospor (C 36,278-Ba).", "content": "Studies of the formation of a violet-reddish pigment from the cephalosporin derivative celospor (C 36,278-Ba).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210891"} {"pmid": "4210893", "title": "Clinical and laboratory investigations on ticarcillin, an anti-pseudomonal antibiotic.", "content": "Clinical and laboratory investigations on ticarcillin, an anti-pseudomonal antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210893"} {"pmid": "4210892", "title": "Preliminary clinical experience with ticarcillin (BRL 2288) in 101 patients treated for severe respiratory infections.", "content": "Preliminary clinical experience with ticarcillin (BRL 2288) in 101 patients treated for severe respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210892"} {"pmid": "4210894", "title": "Interaction aspects of antimycobacterial drugs in the chemotherapy of tuberculosis. II. The role of rifampicin and other drugs in the dependent or independent action of drug associations in vitro.", "content": "Interaction aspects of antimycobacterial drugs in the chemotherapy of tuberculosis. II. The role of rifampicin and other drugs in the dependent or independent action of drug associations in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210894"} {"pmid": "4210895", "title": "Alterations in the sensitivity pattern after use of trimethoprim-sulfamethoxazole for two years in the treatment of urinary tract infections.", "content": "Alterations in the sensitivity pattern after use of trimethoprim-sulfamethoxazole for two years in the treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210895"} {"pmid": "4210916", "title": "Serologic group relationship of P and U streptococci.", "content": "Serologic group relationship of P and U streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210916"} {"pmid": "4210917", "title": "The distribution of blood group frequencies in mainland Tanzania Africans.", "content": "The distribution of blood group frequencies in mainland Tanzania Africans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210917"} {"pmid": "4210918", "title": "Amniotic fluid bilirubin quantitation in the management of the Rh sensitized female.", "content": "Amniotic fluid bilirubin quantitation in the management of the Rh sensitized female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210918"} {"pmid": "4210919", "title": "Microdetermination of alpha-amino-acids through chelation with copper and titration with EDTA.", "content": "Microdetermination of alpha-amino-acids through chelation with copper and titration with EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210919"} {"pmid": "4210924", "title": "Serologic detection of breast cancer.", "content": "Serologic detection of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210924"} {"pmid": "4210923", "title": "Gonococcal infections. Laboratory, clinical and epidemiological aspects.", "content": "Gonococcal infections. Laboratory, clinical and epidemiological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210923"} {"pmid": "4210928", "title": "Studies on the live attenuated rubella virus vaccine.", "content": "Studies on the live attenuated rubella virus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210928"} {"pmid": "4210933", "title": "The Mm. subcostales in man and monkeys.", "content": "The Mm. subcostales in man and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210933"} {"pmid": "4210949", "title": "Pseudomonas resistance due to inactivated susceptibility disks.", "content": "Pseudomonas resistance due to inactivated susceptibility disks. The deterioration of carbenicillin is similar to that of other penicillins. Susceptibility test results, by using disks which have been exposed to humidity, may indicate false resistance. Proper storage and handling methods are suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210949"} {"pmid": "4210950", "title": "Haematological and plasma biochemical parameters in adult male sheep.", "content": "Haematological and plasma biochemical parameters in adult male sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210950"} {"pmid": "4210953", "title": "On the morphology of testicular and ampullar spermatozoa in Egyptian buffalo-bulls.", "content": "On the morphology of testicular and ampullar spermatozoa in Egyptian buffalo-bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210953"} {"pmid": "4210954", "title": "Investigations on urinary oestrogen excretion from ewes with special reference to the clinical condition of the genital tract. 3. Non-breeding season.", "content": "Investigations on urinary oestrogen excretion from ewes with special reference to the clinical condition of the genital tract. 3. Non-breeding season.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210954"} {"pmid": "4210955", "title": "Effect of gestyl on the urinary excretion of oestrogen in ewes during the non-breeding season.", "content": "Effect of gestyl on the urinary excretion of oestrogen in ewes during the non-breeding season.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210955"} {"pmid": "4210957", "title": "Myopathy in an irish terrier with a metabolic defect of the isolated mitochondria.", "content": "Myopathy in an irish terrier with a metabolic defect of the isolated mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210957"} {"pmid": "4210958", "title": "Effect of isonicotinic acid hydrazide and polyvinylpyrrolidone on experimental peritoneal adhesions in the rabbit.", "content": "Effect of isonicotinic acid hydrazide and polyvinylpyrrolidone on experimental peritoneal adhesions in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210958"} {"pmid": "4210968", "title": "Critical issues in infancy and early child development.", "content": "Critical issues in infancy and early child development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210968"} {"pmid": "4210969", "title": "Distribution and life cycle stages of lung mites (Pneumonyssus spp.).", "content": "Distribution and life cycle stages of lung mites (Pneumonyssus spp.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210969"} {"pmid": "4210974", "title": "Solid tissue masses formed in vitro from cells cultured on artificial capillaries.", "content": "Solid tissue masses formed in vitro from cells cultured on artificial capillaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210974"} {"pmid": "4210977", "title": "Letter: Gonorrhea in obstetrics and gynaecology.", "content": "Letter: Gonorrhea in obstetrics and gynaecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210977"} {"pmid": "4210978", "title": "Transabdominal isthmic amniocentesis in RH-immunization with particular reference to complications.", "content": "Transabdominal isthmic amniocentesis in RH-immunization with particular reference to complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210978"} {"pmid": "4210979", "title": "Plasma levels of nonconjugated oestradiol-17beta and oestriol in high risk pregnancies.", "content": "Plasma levels of nonconjugated oestradiol-17beta and oestriol in high risk pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210979"} {"pmid": "4210980", "title": "Dependence of radiation induced aneuploidy from chromosomal length in Drosophila melanogaster. II. X chromosomes and X-4 duplication chromosomes.", "content": "Dependence of radiation induced aneuploidy from chromosomal length in Drosophila melanogaster. II. X chromosomes and X-4 duplication chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210980"} {"pmid": "4210981", "title": "Irradiation-induced crossing-over in Drosophila males. Cytological investigation of crossovers.", "content": "Irradiation-induced crossing-over in Drosophila males. Cytological investigation of crossovers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210981"} {"pmid": "4210982", "title": "Study of the operon of riboflavin biosynthesis in Bacillus subtilis. IV. Regulation of the synthesis of riboflavin synthetase. Investigation of riboflavin transport through the cell membrane.", "content": "Study of the operon of riboflavin biosynthesis in Bacillus subtilis. IV. Regulation of the synthesis of riboflavin synthetase. Investigation of riboflavin transport through the cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210982"} {"pmid": "4210984", "title": "Functional recovery after lesions of the nervous system. II. Recovery of function after lesions of the central nervous system: history and prospects.", "content": "Functional recovery after lesions of the nervous system. II. Recovery of function after lesions of the central nervous system: history and prospects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210984"} {"pmid": "4210985", "title": "Functional recovery after lesions of the nervous system. 3. Developmental processes in neural plasticity. Sparing of language functions after early unilateral brain damage.", "content": "Functional recovery after lesions of the nervous system. 3. Developmental processes in neural plasticity. Sparing of language functions after early unilateral brain damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210985"} {"pmid": "4210986", "title": "Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Equipotentiality and sensorimotor function.", "content": "Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Equipotentiality and sensorimotor function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210986"} {"pmid": "4210987", "title": "Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Redundancy as a possible mechanism for escape or recovery from somatic sensory deficits.", "content": "Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Redundancy as a possible mechanism for escape or recovery from somatic sensory deficits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210987"} {"pmid": "4210988", "title": "Functional recovery after lesions of the nervous system. V. Neural plasticity and behavioral recovery in the central nervous system. Recovery of function after sequential ablation of the frontal lobes of monkeys.", "content": "Functional recovery after lesions of the nervous system. V. Neural plasticity and behavioral recovery in the central nervous system. Recovery of function after sequential ablation of the frontal lobes of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210988"} {"pmid": "4210989", "title": "Mutants of Bacillus subtilis with altered capacity to be donors of DNA in spontaneous transformation. I. Method of isolating mutants.", "content": "Mutants of Bacillus subtilis with altered capacity to be donors of DNA in spontaneous transformation. I. Method of isolating mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210989"} {"pmid": "4210990", "title": "Remote cytogenetic effect of acute irradiation in monkeys. I. Prolonged persistence of chromosome damage in marrow cells.", "content": "Remote cytogenetic effect of acute irradiation in monkeys. I. Prolonged persistence of chromosome damage in marrow cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210990"} {"pmid": "4210991", "title": "Experimental digital replantation after prolonged cooling.", "content": "Experimental digital replantation after prolonged cooling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210991"} {"pmid": "4210996", "title": "Immunological properties of membrane fractions from wild type and dnaA mutants of Escherichia coli.", "content": "Immunological properties of membrane fractions from wild type and dnaA mutants of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210996"} {"pmid": "4210994", "title": "Anaemia in early infancy.", "content": "Anaemia in early infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210994"} {"pmid": "4210997", "title": "DNA polymerase activities in Vero cells infected with herpesvirus Saimiri.", "content": "DNA polymerase activities in Vero cells infected with herpesvirus Saimiri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210997"} {"pmid": "4210999", "title": "Properties of 5'-nucleotidase from Bacillus cereus obtained by washing intact cells with water.", "content": "Properties of 5'-nucleotidase from Bacillus cereus obtained by washing intact cells with water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210999"} {"pmid": "4211000", "title": "Excessive hospitalization can be cut back.", "content": "Excessive hospitalization can be cut back.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211000"} {"pmid": "4211001", "title": "Studies on liver mitochondrial 5'-endonuclease activity in rats fed carcinogenic amines and on their binding to mitochondrial proteins.", "content": "Studies on liver mitochondrial 5'-endonuclease activity in rats fed carcinogenic amines and on their binding to mitochondrial proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211001"} {"pmid": "4210993", "title": "The differential radiologic diagnosis of bone tumors.", "content": "The differential radiologic diagnosis of bone tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4210993"} {"pmid": "4211008", "title": "Histochemical observations on the development of interstitial gland tissue during the maturation of marmoset ovary.", "content": "Histochemical observations on the development of interstitial gland tissue during the maturation of marmoset ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211008"} {"pmid": "4211009", "title": "Fate of auricular transplants and repair of auricular gaps in the grivet monkey (Cercopithecus aethiops aethiops).", "content": "Fate of auricular transplants and repair of auricular gaps in the grivet monkey (Cercopithecus aethiops aethiops).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211009"} {"pmid": "4211012", "title": "Evaluation of amino acid mixtures for total parenteral nutrition.", "content": "Evaluation of amino acid mixtures for total parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211012"} {"pmid": "4211013", "title": "Proceedings: Inhibitory effect of beta-aminopropionitrile on several amine oxidases.", "content": "Proceedings: Inhibitory effect of beta-aminopropionitrile on several amine oxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211013"} {"pmid": "4211016", "title": "Luminal events of lipid absorption in protein-calorie malnourished children; relationship with nutritional recovery and diarrhea. I. Capacity of the duodenal content to achieve micellar solubilization of lipids.", "content": "Luminal events of lipid absorption in protein-calorie malnourished children; relationship with nutritional recovery and diarrhea. I. Capacity of the duodenal content to achieve micellar solubilization of lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211016"} {"pmid": "4211017", "title": "Luminal events of lipid absorption in protein-calorie malnourished children; relationship with nutritional recovery and diarrhea. II. Alterations in bile acid content of duodenal aspirates.", "content": "Luminal events of lipid absorption in protein-calorie malnourished children; relationship with nutritional recovery and diarrhea. II. Alterations in bile acid content of duodenal aspirates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211017"} {"pmid": "4211018", "title": "Vitamin B6 metabolism in women using oral contraceptives.", "content": "Vitamin B6 metabolism in women using oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211018"} {"pmid": "4211019", "title": "Basal energy metabolism in protein-calorie malnutrition and vitamin A deficiency.", "content": "Basal energy metabolism in protein-calorie malnutrition and vitamin A deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211019"} {"pmid": "4211011", "title": "Activity programs for long term care institutions.", "content": "Activity programs for long term care institutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211011"} {"pmid": "4211020", "title": "Properdin factor D. II. Activation to D by properdin.", "content": "Properdin factor D. II. Activation to D by properdin. The protein in the properdin pathway responsible for conversion of precursor factor D to D has been isolated and found to be identical with properdin. Sequential ion exchange and gel filtration chromatography demonstrated identity between properdin protein, measured by radial immunodiffusion, and the capacity to activate D to D, assessed by formation of the intermediate, EAC43B(D). Properdin, purified in this manner, was homogeneous on acid polyacrylamide disc gel electrophoretic analysis, with the band of protein corresponding to the position of eluates in the replicate gel capable of activating highly purified D. Demonstration of the homogeneity of purified D by alkaline disc gel electrophoresis, coupled with the linear stoichiometric hemolytic titrations of each factor, indicates that direct interaction between properdin and D generates D. Thus, activation of D by properdin represents a mechanism in the properdin pathway by which D becomes available for formation of the C3b-dependent C3 convertase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211020"} {"pmid": "4211021", "title": "Specific binding of nerve growth factor (NGF) by murine C 1300 neuroblastoma cells.", "content": "Specific binding of nerve growth factor (NGF) by murine C 1300 neuroblastoma cells. Murine C 1300 neuroblastoma cells bind with high avidity on their membrane surface the nerve growth factor (NGF), a protein capable of inducing differentiation of sympathetic nerve cells. The total binding capacity of NGF by the cells was quantitatively measured by a radioimmunoassay technique, using (125)I-labeled NGF. An average number of about 10(6) molecules of NGF could be bound, at saturation, by each cell with an average relative association constant of about 10(7) liters/mol. Using synchronized cells, it was found, however, that either the number of molecules of ligand bound or the avidity of the binding interaction between NGF and cells varied depending upon their growth cycle, the maximal-binding occurring during the G(1) and early S phase. Binding of [(125)I]NGF was suppressed by trypsin treatment of the cells, however new receptor sites were rapidly replaced onto the membrane surface within 1-2 h. Cells exposed to 3 M KCl released into the supernate a protein product exhibiting similar high avidity for NGF. Acrylamide gel electrophoresis suggested a restricted molecular heterogeneity of this product, with a major component in the 52,000 mol wt region. Antibodies made specific to this protein were capable, in the absence of the complement, of inhibiting the binding of [(125)I]NGF by the cells and in the presence of the complement they killed them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211021"} {"pmid": "4211022", "title": "Schistosoma mansoni: immediate hypersensitivity to adult antigens in the rat.", "content": "Schistosoma mansoni: immediate hypersensitivity to adult antigens in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211022"} {"pmid": "4211023", "title": "Aspects of experimental hepatocarcinogenesis. IV. Changes in the liver following cessation of carcinogen administration.", "content": "Aspects of experimental hepatocarcinogenesis. IV. Changes in the liver following cessation of carcinogen administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211023"} {"pmid": "4211024", "title": "Extended surgical adjuvant thiotepa for mammary carcinoma.", "content": "Extended surgical adjuvant thiotepa for mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211024"} {"pmid": "4211025", "title": "Are elemental diets useful in bowel preparation?", "content": "Are elemental diets useful in bowel preparation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211025"} {"pmid": "4211029", "title": "Identification of lymphocyte-dependent antibody in sera from multiply transfused patients.", "content": "Identification of lymphocyte-dependent antibody in sera from multiply transfused patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211029"} {"pmid": "4211028", "title": "Nephritogenic glycoprotein. 3. Immunochemical studies on nephritogenic activity of homologous water-soluble glycoproteins extracted from various rat organs.", "content": "Nephritogenic glycoprotein. 3. Immunochemical studies on nephritogenic activity of homologous water-soluble glycoproteins extracted from various rat organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211028"} {"pmid": "4211033", "title": "Functional recovery after lesions of the nervous systems. 3. Developmental processes in neural plasticity. Recovery of function after CNS lesions in infant monkeys.", "content": "Functional recovery after lesions of the nervous systems. 3. Developmental processes in neural plasticity. Recovery of function after CNS lesions in infant monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211033"} {"pmid": "4211032", "title": "Carbon-13 nuclear magnetic resonance studies of structure and function in thyrotropin-releasing factor. Determination of the tautomeric form of histidine and relationship to biology activity.", "content": "Carbon-13 nuclear magnetic resonance studies of structure and function in thyrotropin-releasing factor. Determination of the tautomeric form of histidine and relationship to biology activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211032"} {"pmid": "4211034", "title": "Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Recovery of motor function in rhesus monkeys.", "content": "Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Recovery of motor function in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211034"} {"pmid": "4211038", "title": "Iron absorption from Southeast Asian diets.", "content": "Iron absorption from Southeast Asian diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211038"} {"pmid": "4211040", "title": "Macroglobulinemia-myeloma double gammopathy. A study of four cases and a review of the literature.", "content": "Macroglobulinemia-myeloma double gammopathy. A study of four cases and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211040"} {"pmid": "4211043", "title": "The receptor proteins for concanavalin A and Lens culinaris phytohemagglutinin in the membrane of the human erythrocyte.", "content": "The receptor proteins for concanavalin A and Lens culinaris phytohemagglutinin in the membrane of the human erythrocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211043"} {"pmid": "4211044", "title": "Regulation of aromatic amino acid biosynthesis in Bacillus subtilis 168. Purification, characterization, and subunit structure of the bifunctional enzyme 3-deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase.", "content": "Regulation of aromatic amino acid biosynthesis in Bacillus subtilis 168. Purification, characterization, and subunit structure of the bifunctional enzyme 3-deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211044"} {"pmid": "4211048", "title": "Formation and release of 3H-tryptamine from 3H-tryptophan in rat spinal cord slices.", "content": "Formation and release of 3H-tryptamine from 3H-tryptophan in rat spinal cord slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211048"} {"pmid": "4211049", "title": "The effect of ventromedial tegmental lesions on the disposition and biosynthesis of dopamine and serotonin.", "content": "The effect of ventromedial tegmental lesions on the disposition and biosynthesis of dopamine and serotonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211049"} {"pmid": "4211050", "title": "Giant duodenal diverticula.", "content": "Giant duodenal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211050"} {"pmid": "4211052", "title": "Large diverticulum of the anal canal. Case report and review of the literature on anal canal and rectal diverticula.", "content": "Large diverticulum of the anal canal. Case report and review of the literature on anal canal and rectal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211052"} {"pmid": "4211053", "title": "Radiotherapy of tumors of the urinary tract. Hickey lecture, 1974.", "content": "Radiotherapy of tumors of the urinary tract. Hickey lecture, 1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211053"} {"pmid": "4211051", "title": "Giant sigmoid diverticulum.", "content": "Giant sigmoid diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211051"} {"pmid": "4211054", "title": "Studies on the E strain of Rickettsia prowazeki.", "content": "Studies on the E strain of Rickettsia prowazeki. Cultivation of E strain of Rickettsia prowazeki in mouse lung resulted in a marked increase in virulence for guinea pigs following 12 passages (but not 6 passages) in both immunosuppressed and normal mice. Attempts at passaging E strain in normal guinea pigs were unsuccessful. Isolates of E strain in the chicken embryo yolk sac either from testes and peritoneal washings or from the brain of immunosuppressed guinea pigs did not show enhanced virulence for guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211054"} {"pmid": "4211055", "title": "Immuno-epidemiology of malaria: a study in a tribal area of West Irian.", "content": "Immuno-epidemiology of malaria: a study in a tribal area of West Irian. An investigation of malariometric indices in relation to immunoglobulin levels, rheumatoid factors, and antithyroglobulins was carried out on 78 members of the Arfak tribe near Manokwari in Western New Guinea, in the course of a WHO assessment of malaria control activities in that region. The population investigated had been exposed to a period of epidemic malaria, as indicated by the small differences in malariometric indices between consecutive age groups. Typically high spleen sizes were recorded, as found generally among Papuans in similar situations. Falciparum malaria was most prevalent, almost equal to cases of vivax and malariae malaria together. IgM levels were very high, while those of IgG, IgA and IgD were not elevated. Total serum protein was rather low. No correlation between malariometric indices, autoantibodies, and immunoglobulin levels could be found. In particular there was no correlation between IgM levels and spleen indices, such as has been found in many other surveys. It is suggested that splenomegaly may show no correlation with the IgM level in Papuan populations without previous selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211055"} {"pmid": "4211056", "title": "A serogroup A meningococcal polysaccharide vaccine: studies in the Sudan to combat cerebrospinal meningitis caused by Neisseria meningitidis group A.", "content": "A serogroup A meningococcal polysaccharide vaccine: studies in the Sudan to combat cerebrospinal meningitis caused by Neisseria meningitidis group A. Vaccination against cerebrospinal meningitis (CSM) has regained interest with the use of capsular polysaccharides (or polyosides) of the meningococcus as specific immunizing agents. These compounds proved to be effective in the USA against meningitis caused by Neisseria meningitidis serotype C. This study considers whether the polysaccharides of the serotype A meningococcus, which is prevalent in the African CSM belt, could be protective in epidemic conditions. Taking advantage of the usual seasonal peak of CSM cases, controlled field trials were undertaken in the Sudan early in 1973. 21 640 persons were vaccinated, half of them with a meningococcal polyoside A vaccine and the other half with tetanus toxoid as a placebo. In the former group there were no cases of meningitis, whereas in the latter 10 cases were reported, of which 7 were confirmed by laboratory tests. These studies indicate that the meningococcal polyoside A vaccine is efficient in epidemic conditions and could be used to control outbreaks of meningococcal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211056"} {"pmid": "4211057", "title": "Comparison of indirect haemagglutination and immunofluorescence tests for malaria antibody in Aotus monkeys infected with Plasmodium falciparum. Application of indirect haemagglutination tests for malaria.", "content": "Comparison of indirect haemagglutination and immunofluorescence tests for malaria antibody in Aotus monkeys infected with Plasmodium falciparum. Application of indirect haemagglutination tests for malaria. Longitudinal observations were made on 6 Aotus monkeys repeatedly infected with Plasmodium falciparum (West African and Palo Alto strains). Immunofluorescence titres were higher than indirect haemagglutination titres in the primary phase of the infections. Both serological tests were consistently positive later in the infections. Precipitins were often not detectable even during episodes of parasitaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211057"} {"pmid": "4211058", "title": "Application of the indirect haemagglutination test for malaria: reproducibility with Plasmodium falciparum-sensitized cells.", "content": "Application of the indirect haemagglutination test for malaria: reproducibility with Plasmodium falciparum-sensitized cells. The reproducibility of the IHA test was assessed. Two batches of glutaraldehyde-fixed sheep cells were used and the cells were sensitized with different batches of P. falciparum antigen obtained from 4 owl monkeys. At the individual level the IHA test appears to have a reproducibility of approximately 90%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211058"} {"pmid": "4211071", "title": "Tooth root abscess and fistula in the squirrel monkey (Saimiri sciureus).", "content": "Tooth root abscess and fistula in the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211071"} {"pmid": "4211087", "title": "Sustained effects of nitroglycerin ointment in patients with angina pectoris.", "content": "Sustained effects of nitroglycerin ointment in patients with angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211087"} {"pmid": "4211088", "title": "Biotransformation of diethyl ether and chloroform.", "content": "Biotransformation of diethyl ether and chloroform.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211088"} {"pmid": "4211089", "title": "Three pregnancy-associated human plasma proteins: purification, monospecific antisera and immunological indentification.", "content": "Three pregnancy-associated human plasma proteins: purification, monospecific antisera and immunological indentification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211089"} {"pmid": "4211091", "title": "The recovery of indicator bacteria on selective media.", "content": "The recovery of indicator bacteria on selective media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211091"} {"pmid": "4211092", "title": "Studies on the mechanism of the sporicidal action of glutaraldehyde.", "content": "Studies on the mechanism of the sporicidal action of glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211092"} {"pmid": "4211094", "title": "Characterization of pesticin. Separation of antibacterial activities.", "content": "Characterization of pesticin. Separation of antibacterial activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211094"} {"pmid": "4211095", "title": "Studies on the group-specific polysaccharide of Neisseria meningitidis serogroup X and an improved procedure for its isolation.", "content": "Studies on the group-specific polysaccharide of Neisseria meningitidis serogroup X and an improved procedure for its isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211095"} {"pmid": "4211096", "title": "Biosynthesis of peptidoglycan in the one million molecular weight range by membrane preparations from Bacillus megaterium.", "content": "Biosynthesis of peptidoglycan in the one million molecular weight range by membrane preparations from Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211096"} {"pmid": "4211097", "title": "Synthesis of cross-linked peptidoglycan attached to previously formed cell wall by toluene-treated cells of Bacillus megaterium.", "content": "Synthesis of cross-linked peptidoglycan attached to previously formed cell wall by toluene-treated cells of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211097"} {"pmid": "4211099", "title": "Purification and characterization of the thermophilic D-alanine carboxypeptidase from membranes of Bacillus stearothermophilus.", "content": "Purification and characterization of the thermophilic D-alanine carboxypeptidase from membranes of Bacillus stearothermophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211099"} {"pmid": "4211100", "title": "Principles of parenteral alimentation.", "content": "Principles of parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211100"} {"pmid": "4211098", "title": "Characterization of the forssman glycolipid hapten of horse kidney by mass spectrometry.", "content": "Characterization of the forssman glycolipid hapten of horse kidney by mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211098"} {"pmid": "4211102", "title": "Radiation therapy in Hodgkin's disease.", "content": "Radiation therapy in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211102"} {"pmid": "4211101", "title": "Unitary responses in frog olfactory epithelium to sterically related molecules at low concentrations.", "content": "Unitary responses in frog olfactory epithelium to sterically related molecules at low concentrations. Responses of receptor cells in the frog's olfactory epithelium were recorded using platinum-black metal-filled microelectrodes. Spontaneous activity varied over a wide range from 0.07 to 1.8 spikes/s. Mean interspike intervals ranged from 13.7 to 0.5 s. Excitatory responses to six sterically related compounds at low concentrations were investigated. Stimuli were delivered in an aqueous medium. Thresholds for impulse initiation varied from greater than 1 mM down to the nanomolar concentration range. Thresholds of different olfactory receptors to the same stimulus could vary by several log units. Thresholds of the same receptor cell to different stimuli could be within the same order of magnitude, or could vary by as much as 5 log units. Based upon quantitative measures of stimulus-evoked excitatory responses it appeared that some receptors did not discriminate among sterically related molecules, whereas other receptors clearly discriminated between stimuli which evoke similar odor sensations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211101"} {"pmid": "4211107", "title": "Utilization of thioridazine combined with hydergine in the treatment of incipient mental disturbances in cerebral atherosclerosis.", "content": "Utilization of thioridazine combined with hydergine in the treatment of incipient mental disturbances in cerebral atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211107"} {"pmid": "4211111", "title": "Vitellogenetic processes and cytochemical aspects in the growing oocytes of the bentonic teleost Mugil chelo CUV.", "content": "Vitellogenetic processes and cytochemical aspects in the growing oocytes of the bentonic teleost Mugil chelo CUV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211111"} {"pmid": "4211114", "title": "Ultrastructural cytochemical study of acid phosphatase in bovine ruminal epithelium.", "content": "Ultrastructural cytochemical study of acid phosphatase in bovine ruminal epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211114"} {"pmid": "4211116", "title": "Alkaline phosphatase activity in differentiating liver of chick. A histochemical and quantitative study.", "content": "Alkaline phosphatase activity in differentiating liver of chick. A histochemical and quantitative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211116"} {"pmid": "4211119", "title": "Histochemical studies on the chorioid plexuses of the goat embryos. 3. Histochemical distribution of acid and alkaline phosphatases.", "content": "Histochemical studies on the chorioid plexuses of the goat embryos. 3. Histochemical distribution of acid and alkaline phosphatases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211119"} {"pmid": "4211120", "title": "A histochemical study of some aspects of the metabolism of glutamic acid in the cerebellum of mammals.", "content": "A histochemical study of some aspects of the metabolism of glutamic acid in the cerebellum of mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211120"} {"pmid": "4211122", "title": "Demonstration and interspecies cross-sensitization of reaginic antibodies in dogs infected with Dirofilaria immitis.", "content": "Demonstration and interspecies cross-sensitization of reaginic antibodies in dogs infected with Dirofilaria immitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211122"} {"pmid": "4211123", "title": "Scrub typhus in eastern Taiwan, 1970.", "content": "Scrub typhus in eastern Taiwan, 1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211123"} {"pmid": "4211124", "title": "Exoerythrocytic stages of Plasmodium vivax in Ateles monkeys.", "content": "Exoerythrocytic stages of Plasmodium vivax in Ateles monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211124"} {"pmid": "4211125", "title": "On the interaction of Ricinus communis lectin with plant amyloids.", "content": "On the interaction of Ricinus communis lectin with plant amyloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211125"} {"pmid": "4211136", "title": "Electroimmunodiffusion of IgG heavy chains in nanogram quantities with a carboxymethyl-cellulose-agarose gel.", "content": "Electroimmunodiffusion of IgG heavy chains in nanogram quantities with a carboxymethyl-cellulose-agarose gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211136"} {"pmid": "4211137", "title": "A new topical steroid-antibiotic combination, diprogenta.", "content": "A new topical steroid-antibiotic combination, diprogenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211137"} {"pmid": "4211138", "title": "A multicentric trial of a new steroid, betamethasone benzoate, in common dermatological disorders.", "content": "A multicentric trial of a new steroid, betamethasone benzoate, in common dermatological disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211138"} {"pmid": "4211139", "title": "Improvement of long-standing ventricular premature beats following prednisone therapy.", "content": "Improvement of long-standing ventricular premature beats following prednisone therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211139"} {"pmid": "4211140", "title": "Long-term safety of Nefopam hydrochloride (Acupan), a new analgesic formulation.", "content": "Long-term safety of Nefopam hydrochloride (Acupan), a new analgesic formulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211140"} {"pmid": "4211141", "title": "A clinical evaluation of nefopam hydrochloride (Acupan): a new analgesic.", "content": "A clinical evaluation of nefopam hydrochloride (Acupan): a new analgesic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211141"} {"pmid": "4211142", "title": "An evaluation of the effectiveness of simethicone in acute upper gastrointesinal distress.", "content": "An evaluation of the effectiveness of simethicone in acute upper gastrointesinal distress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211142"} {"pmid": "4211144", "title": "A pilot study of ORF 8063, a new benzodiazepine in anxious alcoholic patients.", "content": "A pilot study of ORF 8063, a new benzodiazepine in anxious alcoholic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211144"} {"pmid": "4211143", "title": "Glaziovine versus diazepam: a double-blind clinical trial.", "content": "Glaziovine versus diazepam: a double-blind clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211143"} {"pmid": "4211145", "title": "Methylphenidate in children with minimal brain dysfunction: effects on attention span, visual-motor skills, and behavior.", "content": "Methylphenidate in children with minimal brain dysfunction: effects on attention span, visual-motor skills, and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211145"} {"pmid": "4211146", "title": "Clinical and computerized EEG effects of U-31,920, a new anxiolytic.", "content": "Clinical and computerized EEG effects of U-31,920, a new anxiolytic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211146"} {"pmid": "4211147", "title": "Vitamin C prophylaxis and some problems of statistical inference.", "content": "Vitamin C prophylaxis and some problems of statistical inference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211147"} {"pmid": "4211148", "title": "Nicotinic acid plasma concentrations after ingestion of 1,3,4,6-tetranicotinoyl-fructo-furanose (tetranicotinoylfructose, nicofuranose).", "content": "Nicotinic acid plasma concentrations after ingestion of 1,3,4,6-tetranicotinoyl-fructo-furanose (tetranicotinoylfructose, nicofuranose).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211148"} {"pmid": "4211149", "title": "Physiology of spores of mycobacillin producer and non-producer mutants of Bacillus sbutilis.", "content": "Physiology of spores of mycobacillin producer and non-producer mutants of Bacillus sbutilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211149"} {"pmid": "4211150", "title": "Respiration and metabolic processes of bacteria in autoclaved and gamma-irradiated soil.", "content": "Respiration and metabolic processes of bacteria in autoclaved and gamma-irradiated soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211150"} {"pmid": "4211151", "title": "An effect of centromere function on the behavior of ring-X chromosomes in Drosophila melanogaster.", "content": "An effect of centromere function on the behavior of ring-X chromosomes in Drosophila melanogaster. It is shown that under the influence of an autosomal meiotic mutant that causes abnormalities in meiotic centromere function (mei-S332), ring-X chromosomes are frequently nonrecoverable. Evidence is presented that this nonrecoverability is caused by a failure of sister ring-chromatids to successfully effect an equational separation with resultant dominant lethality. Because mei-S332 results in meiotic abnormalities only after replication has been completed, and because ring chromosomes are normally transmitted with approximately the same efficiency as rod chromosomes, it is suggested that during replication in normal meioses, sister ring-chromatids form mutually interlocked ring complexes that are resolved without genetic consequences at anaphase II, with the resolution owing at least in part to normal centromere function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211151"} {"pmid": "4211152", "title": "Microdifferentiation in a natural population of Drosophila melanogaster to alcohol in the environment.", "content": "Microdifferentiation in a natural population of Drosophila melanogaster to alcohol in the environment. Strains of D. melanogaster derived from a vineyard population were more resistant to alcohol in the environment than strains from a population derived from an area removed from the vineyard. Within the vineyard population those strains most closely associated with alcohol in the environment in the cellar were more resistant than those collected outside the cellar. There was evidence of gene flow between the inside and outside cellar components of this population, but microdifferentiation had occurred within the cellar in spite of this. The adaptation appears to be independent of the ADH system and involves both additive and dominance genetic effects. D. simulans, a species not found in the cellar and susceptible to the presence of alcohol, showed no differentiation between vineyard and removed populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211152"} {"pmid": "4211153", "title": "Glycol methacrylate embedding in enzyme histochemistry: application to arthropode tissue incubated for demonstration of unspecific esterase and succinic dehydrogenase activity.", "content": "Glycol methacrylate embedding in enzyme histochemistry: application to arthropode tissue incubated for demonstration of unspecific esterase and succinic dehydrogenase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211153"} {"pmid": "4211154", "title": "Analysis for possible linkage between the loci for the Waardenburg syndrome and various blood groups and serological traits.", "content": "Analysis for possible linkage between the loci for the Waardenburg syndrome and various blood groups and serological traits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211154"} {"pmid": "4211156", "title": "The effects of chemical modification by N-bromosuccinimide of saccharifying alpha-amylase from Bacillus subtilis on various substrates.", "content": "The effects of chemical modification by N-bromosuccinimide of saccharifying alpha-amylase from Bacillus subtilis on various substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211156"} {"pmid": "4211155", "title": "A study of diabetes in relation to blood groups and cholesterol levels.", "content": "A study of diabetes in relation to blood groups and cholesterol levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211155"} {"pmid": "4211158", "title": "Subacute sepsis of the hip treated by antibiotics and cemented prosthesis.", "content": "Subacute sepsis of the hip treated by antibiotics and cemented prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211158"} {"pmid": "4211157", "title": "Sensitivity of Escherichia coli to viral nucleic acid. 8. Idiosyncrasy of Ca2+-dependent competence for DNA.", "content": "Sensitivity of Escherichia coli to viral nucleic acid. 8. Idiosyncrasy of Ca2+-dependent competence for DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211157"} {"pmid": "4211159", "title": "Precise evaluation of the reduction of severe ankle fractures.", "content": "Precise evaluation of the reduction of severe ankle fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211159"} {"pmid": "4211162", "title": "Physiopathology of the cerebellum in the monkey. I. Origin of cerebellar afferent nervous fibers from the spinal cord and brain stem.", "content": "Physiopathology of the cerebellum in the monkey. I. Origin of cerebellar afferent nervous fibers from the spinal cord and brain stem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211162"} {"pmid": "4211161", "title": "Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport.", "content": "Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport. A soluble fatty acid-binding protein (FABP), mol wt approximately 12,000 is present in intestinal mucosa and other tissues that utilize fatty acids, including liver, myocardium, adipose, and kidney. This protein binds long chain fatty acids both in vivo and in vitro.FABP was isolated from rat intestine by gel filtration and isoelectric focusing. It showed a reaction of complete immunochemical identity with proteins in the 12,000 mol wt fatty acid-binding fractions of liver, myocardium, and adipose tissue supernates. (The presence of immunochemically nonidentical 12,000 mol wt FABP in these tissues is not excluded.) By quantitative radial immunodiffusion, supernatant FABP concentration in mucosa from proximal and middle thirds of jejuno-ileum significantly exceeded that in distal third, duodenum, and liver, expressed as micrograms per milligram soluble protein, micrograms per gram DNA, and micrograms per gram tissue. FABP concentration in villi was approximately three times greater than in crypts. Small quantities of FABP were present in washed nuclei-cell membrane, mitochondrial and microsomal fractions. However, the amount of FABP solubilized per milligram membrane protein was similar for all particulate fractions, and total membrane-associated FABP was only about 16% of supernatant FABP. Intestinal FABP concentration was significantly greater in animals maintained on high fat diets than on low fat; saturated and unsaturated fat diets did not differ greatly in this regard.The preponderance of FABP in villi from proximal and middle intestine, its ability to bind fatty acids in vivo as well as in vitro, and its response to changes in dietary fat intake support the concept that this protein participates in cellular fatty acid transport during fat absorption. Identical or closely related 12,000 mol wt proteins may serve similar functions in other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211161"} {"pmid": "4211160", "title": "Effects of hemorrhage on regional blood flow distribution in dogs and primates.", "content": "Effects of hemorrhage on regional blood flow distribution in dogs and primates. The effects of hemorrhage on arterial pressure, blood flows, and resistances in the coronary, mesenteric, renal, and iliac beds of healthy, conscious dogs and intact, tranquilized baboons were studied. Mild nonhypotensive hemorrhage (14+/-2 ml/kg) increased heart rate and mesenteric and iliac resistances slightly but significantly, and decreased renal resistance (-13+/-2%). Moderate hypotensive hemorrhage, 26+/-2 ml/kg, reduced mean arterial pressure (-23+/-2 mm Hg) and blood flows to the mesenteric (-56+/-3%), iliac (-58+/-5%), and coronary (-39+/-4%) vascular beds, and increased heart rate (+89+/-9 beats/min) and resistances in the mesenteric (+73+/-15%), iliac (+102+/-19%), and coronary (+27+/-5%) beds. In contrast to the other beds, renal flow rose 11+/-6% above control and renal resistance fell 31+/-2% below control. Renal vasodilatation with hemorrhage was also observed in five baboons. The increases in mesenteric and iliac resistances were blocked almost completely by phentolamine, while the increase in coronary resistance was only partially blocked by phentolamine. The renal dilatation was not blocked by phentolamine, propranolol, atropine, or tripelennamine, but was prevented by indomethacin, suggesting that this dilatation was mediated by a prostaglandin-like compound. Thus the peripheral vascular responses to hemorrhage involve intense vasoconstriction in the mesenteric and iliac beds. In the normal conscious dog and the intact, tranquilized primate, the renal bed does not share in the augmentation of total peripheral resistance with nonhypotensive and moderate hypotensive hemorrhage, but does with more severe hemorrhage. In fact, renal vasodilatation occurs with nonhypotensive or moderate hypotensive hemorrhage, which can be prevented by blockade of prostaglandin synthetase with indomethacin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211160"} {"pmid": "4211163", "title": "Physiopathology of the cerebellum in the monkey. 2. Motor disturbances associated with partial and complete destruction of cerebellar structures.", "content": "Physiopathology of the cerebellum in the monkey. 2. Motor disturbances associated with partial and complete destruction of cerebellar structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211163"} {"pmid": "4211164", "title": "Effects of d-amphetamine, morphine and chlorpromazine on responding under fixed-interval schedules of food presentation or electric shock presentation.", "content": "Effects of d-amphetamine, morphine and chlorpromazine on responding under fixed-interval schedules of food presentation or electric shock presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211164"} {"pmid": "4211165", "title": "Mechanism of the vasoconstrictor action of prostaglandin B.", "content": "Mechanism of the vasoconstrictor action of prostaglandin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211165"} {"pmid": "4211166", "title": "In vitro synthesis of adenovirus core proteins.", "content": "In vitro synthesis of adenovirus core proteins. mRNA extracted from polysomes of KB cells at late stages of productive infection with adenovirus type 2 was translated in a cell-free system derived from Krebs II ascites cells. Two of the polypeptides obtained in this reaction corresponded to the adenovirus core protein V and the precursor to core protein VII. The following criteria were used to establish identity between the in vitro products and the virion proteins: comigration during sodium dodecyl sulfatepolyacrylamide gel electrophoresis, cochromatography in sodium dodecyl sulfate-hydroxyapatite, specific immunoprecipitation of the precursor to core protein VII, and tryptic peptide analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211166"} {"pmid": "4211169", "title": "Isolation of Yersinia enterocolitica from monkeys and deers.", "content": "Isolation of Yersinia enterocolitica from monkeys and deers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211169"} {"pmid": "4211167", "title": "Transformation potentials of the noninfectious (defective) component in pools of adenoviruses type 12 and simian adenovirus 7.", "content": "Transformation potentials of the noninfectious (defective) component in pools of adenoviruses type 12 and simian adenovirus 7. Pools of adenovirus 12 and simian adenovirus 7 were separated into four or five fractions by density gradient centrifugation in cesium chloride. Each fraction was analyzed for total in vitro infectivity units, total transformation activity, and for total virus particle (VP) content. Two major subpopulations were separated with mean densities of 1.30 +/- 0.02 and 1.34 +/- 0.02 g/ml, respectively. Virions in the 1.34 g/ml range were highly infectious (10(2) to 10(3) VP per infectivity unit) in contrast to virions at 1.30 g/ml density (10(4) to 10(5) VP per infectivity units). Transformation capacity was evenly distributed throughout fractions of both viruses, indicating that genetically incomplete or defective virus particles were not deficient in their ability to induce transformation. The average VP per transformation unit for adenovirus 12 (2.85 x 10(6)) and for simian adenovirus 7 (4.00 x 10(6)) did not vary significantly from fraction to fraction. These values were obtained with optimal input multiplicities of 16 to 64 VP per cell. At higher multiplicities the apparent increase in VP per transformation unit was attributable to the viral cytocidal effect on hamster cells. These studies revealed that quantitation of in vitro transformation based on VP multiplicities was more reliable than on the basis of infectious units. These estimates were independent of method of virus production, extraction, and purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211167"} {"pmid": "4211168", "title": "Bacillus subtilis bacteriophage SP01, SP82, and phi e require host lysyl- and tryptophanyl-tRNA synthetases for phage development.", "content": "Bacillus subtilis bacteriophage SP01, SP82, and phi e require host lysyl- and tryptophanyl-tRNA synthetases for phage development. Infection of Bacillus subtilis mutants having temperature-sensitive lysyl- or tryptophanyl-tRNA synthetases with bacteriophage SP01, SP82, or phie indicates that both host enzymes are essential for phage development. No apparent modification of the temperature-sensitive phenotype of the mutant host enzymes occurs during phage infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211168"} {"pmid": "4211170", "title": "Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis.", "content": "Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211170"} {"pmid": "4211176", "title": "Compensating victims of violent crime.", "content": "Compensating victims of violent crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211176"} {"pmid": "4211174", "title": "The behavioral pharmacology of Sch 12679. A new psychoactive agent.", "content": "The behavioral pharmacology of Sch 12679. A new psychoactive agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211174"} {"pmid": "4211177", "title": "The fate of (14C)phenol in various species.", "content": "The fate of (14C)phenol in various species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211177"} {"pmid": "4211178", "title": "Metabolism of 3-acetamido-6-methyl-8-n-propyl-s-triazolo (4,3-a)pyrazine (I.C.I. 58,301) in animals.", "content": "Metabolism of 3-acetamido-6-methyl-8-n-propyl-s-triazolo (4,3-a)pyrazine (I.C.I. 58,301) in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211178"} {"pmid": "4211179", "title": "The metabolism of sulphadimethoxypyrimidine.", "content": "The metabolism of sulphadimethoxypyrimidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211179"} {"pmid": "4211180", "title": "Folate binding in animal plasma.", "content": "Folate binding in animal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211180"} {"pmid": "4211181", "title": "Turnover of lysozyme-positive monocytes in normal rat blood.", "content": "Turnover of lysozyme-positive monocytes in normal rat blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211181"} {"pmid": "4211182", "title": "Globin chain synthesis in sickle cell trait under conditions of folate antagonism.", "content": "Globin chain synthesis in sickle cell trait under conditions of folate antagonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211182"} {"pmid": "4211184", "title": "Disodium cromoglycate in the treatment of allergic asthma.", "content": "Disodium cromoglycate in the treatment of allergic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211184"} {"pmid": "4211183", "title": "First report of Hb E in Italy.", "content": "First report of Hb E in Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211183"} {"pmid": "4211185", "title": "A rapid screening test for detection of alpha-1 fetoprotein as an indicator of fetal distress.", "content": "A rapid screening test for detection of alpha-1 fetoprotein as an indicator of fetal distress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211185"} {"pmid": "4211186", "title": "Family with a high activity of serum diamine oxidase.", "content": "Family with a high activity of serum diamine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211186"} {"pmid": "4211188", "title": "Ocular histopathology of Norrie's disease.", "content": "Ocular histopathology of Norrie's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211188"} {"pmid": "4211187", "title": "The eyes of embryos with chromosome abnormalities.", "content": "The eyes of embryos with chromosome abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211187"} {"pmid": "4211189", "title": "Experimental retinal detachment in the owl monkey. 11. The role of light in photoreceptor atrophy.", "content": "Experimental retinal detachment in the owl monkey. 11. The role of light in photoreceptor atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211189"} {"pmid": "4211190", "title": "Corneal cryopreservation and the fate of corneal cells in penetrating keratoplasty.", "content": "Corneal cryopreservation and the fate of corneal cells in penetrating keratoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211190"} {"pmid": "4211191", "title": "Retinal degeneration in a baboon.", "content": "Retinal degeneration in a baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211191"} {"pmid": "4211193", "title": "An evaluation of tobramycin in experimental corneal ulcers.", "content": "An evaluation of tobramycin in experimental corneal ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211193"} {"pmid": "4211192", "title": "Effect of nitrous oxide on air in vitreous.", "content": "Effect of nitrous oxide on air in vitreous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211192"} {"pmid": "4211206", "title": "Population ecology of Sulfolobus acidocaldarius. II. Immunoecolgical studies.", "content": "Population ecology of Sulfolobus acidocaldarius. II. Immunoecolgical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211206"} {"pmid": "4211207", "title": "Incorporation of labelled amino acids by nuclei isolated from Euglena gracilis.", "content": "Incorporation of labelled amino acids by nuclei isolated from Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211207"} {"pmid": "4211208", "title": "Inhibition of carotenoid synthesis in Myxococcus fulvus (Myxobacterales).", "content": "Inhibition of carotenoid synthesis in Myxococcus fulvus (Myxobacterales).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211208"} {"pmid": "4211209", "title": "Mixed carbon source effect in the phenazine-alpha-carboxylic acid synthesis and the aromatic pathway in Pseudomonas spp.", "content": "Mixed carbon source effect in the phenazine-alpha-carboxylic acid synthesis and the aromatic pathway in Pseudomonas spp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211209"} {"pmid": "4211210", "title": "Isolation, enumeration, and host range of marine Bdellovibrios.", "content": "Isolation, enumeration, and host range of marine Bdellovibrios.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211210"} {"pmid": "4211212", "title": "Formation and regeneration of Penicillium chrysogenum protoplasts.", "content": "Formation and regeneration of Penicillium chrysogenum protoplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211212"} {"pmid": "4211211", "title": "Endocytosis and the adaptive acid hydrolases in Tetrahymena pyriformis GL.", "content": "Endocytosis and the adaptive acid hydrolases in Tetrahymena pyriformis GL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211211"} {"pmid": "4211213", "title": "In vivo survival of cryopreserved endothelial cells in primates.", "content": "In vivo survival of cryopreserved endothelial cells in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211213"} {"pmid": "4211214", "title": "Intravitreal injection of dexamethasone. Treatment of experimentally induced endophthalmitis.", "content": "Intravitreal injection of dexamethasone. Treatment of experimentally induced endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211214"} {"pmid": "4211216", "title": "Effect of prostaglandin E1 administration on the heart glycogen synthase and phosphorylase systems.", "content": "Effect of prostaglandin E1 administration on the heart glycogen synthase and phosphorylase systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211216"} {"pmid": "4211217", "title": "Oxidative phosphorylation and respiration by liver mitochondria from polychlorinated biphenyl-intoxicated rats.", "content": "Oxidative phosphorylation and respiration by liver mitochondria from polychlorinated biphenyl-intoxicated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211217"} {"pmid": "4211218", "title": "N-methylation of biogenic amines. I. Characterization and properties of an N-methyltransferase in rat brain using 5-methyltetrahydrofolic acid as the methyl donor.", "content": "N-methylation of biogenic amines. I. Characterization and properties of an N-methyltransferase in rat brain using 5-methyltetrahydrofolic acid as the methyl donor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211218"} {"pmid": "4211219", "title": "Acid denaturation of bovine carbonic anhydrase B.", "content": "Acid denaturation of bovine carbonic anhydrase B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211219"} {"pmid": "4211220", "title": "Structure of the mannan form Saccharomyces strain FH4C, a mutant constitutive for invertase biosynthesis. I. Significance of phosphate to the structure and refractoriness of the molecule.", "content": "Structure of the mannan form Saccharomyces strain FH4C, a mutant constitutive for invertase biosynthesis. I. Significance of phosphate to the structure and refractoriness of the molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211220"} {"pmid": "4211222", "title": "Occurrence of trans-phytoene in microorganisms grown in the absence of carotenogenesis inhibitors.", "content": "Occurrence of trans-phytoene in microorganisms grown in the absence of carotenogenesis inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211222"} {"pmid": "4211221", "title": "Reserpine as an uncoupling agent.", "content": "Reserpine as an uncoupling agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211221"} {"pmid": "4211223", "title": "Genes and isoenzymes controlling the first step in the aromatic amino acid biosynthesis in Schizosaccharomyces pombe.", "content": "Genes and isoenzymes controlling the first step in the aromatic amino acid biosynthesis in Schizosaccharomyces pombe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211223"} {"pmid": "4211225", "title": "Studies of substrate hydrolysis by an esterase isozyme of rat serum.", "content": "Studies of substrate hydrolysis by an esterase isozyme of rat serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211225"} {"pmid": "4211224", "title": "Bacterial citrate synthases: purification, molecular weight and kinetic mechanism.", "content": "Bacterial citrate synthases: purification, molecular weight and kinetic mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211224"} {"pmid": "4211227", "title": "The cells of origin of the corpus callosum in rat, cat and rhesus monkey.", "content": "The cells of origin of the corpus callosum in rat, cat and rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211227"} {"pmid": "4211226", "title": "The electron microscopical structure of thyroglobulin obtained by micropuncture of rat thyroid follicles.", "content": "The electron microscopical structure of thyroglobulin obtained by micropuncture of rat thyroid follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211226"} {"pmid": "4211229", "title": "Peptides with NH2-terminal tryptophan in the adenohypophysis. A chemical and fluorescence histochemical study.", "content": "Peptides with NH2-terminal tryptophan in the adenohypophysis. A chemical and fluorescence histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211229"} {"pmid": "4211233", "title": "Immunoglobulin classes in Xenopus laevis.", "content": "Immunoglobulin classes in Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211233"} {"pmid": "4211234", "title": "Deviation and laterality of hand preference in monkeys.", "content": "Deviation and laterality of hand preference in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211234"} {"pmid": "4211236", "title": "Identification of 4-chloro-4'-hydroxybiphenyl and 4,4'-dichloro-3-hydroxybiphenyl as metabolites of 4-chloro- and 4,4'-dichlorobiphenyl fed to rats.", "content": "Identification of 4-chloro-4'-hydroxybiphenyl and 4,4'-dichloro-3-hydroxybiphenyl as metabolites of 4-chloro- and 4,4'-dichlorobiphenyl fed to rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211236"} {"pmid": "4211237", "title": "In vitro antibacterial activity of 2-amino-4(2-ethynyl-1-methyl-5-nitroimidazole)-pyrimidine, a metronidazole derivative with antitrichomonad activity.", "content": "In vitro antibacterial activity of 2-amino-4(2-ethynyl-1-methyl-5-nitroimidazole)-pyrimidine, a metronidazole derivative with antitrichomonad activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211237"} {"pmid": "4211238", "title": "Gold thioglucose induced terminal degeneration in mouse hypothalamus.", "content": "Gold thioglucose induced terminal degeneration in mouse hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211238"} {"pmid": "4211239", "title": "Effect of hemorrhage on electrical and PH gradients in the intact stomach of the subhuman primate.", "content": "Effect of hemorrhage on electrical and PH gradients in the intact stomach of the subhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211239"} {"pmid": "4211242", "title": "Opaque arthrography of the temporomandibular joint.", "content": "Opaque arthrography of the temporomandibular joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211242"} {"pmid": "4211243", "title": "An assessment of the use of prophylactic antibiotics in third molar surgery.", "content": "An assessment of the use of prophylactic antibiotics in third molar surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211243"} {"pmid": "4211244", "title": "Suicidal gunshot wounds resulting in severe maxillofacial injury.", "content": "Suicidal gunshot wounds resulting in severe maxillofacial injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211244"} {"pmid": "4211245", "title": "A desmoplastic fibroma in the mandible.", "content": "A desmoplastic fibroma in the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211245"} {"pmid": "4211235", "title": "Reovirus infected cells for studying microtubules and spindle poisons.", "content": "Reovirus infected cells for studying microtubules and spindle poisons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211235"} {"pmid": "4211246", "title": "Epithelial cells in the periodontal membrane of teeth with and without periapical inflammation.", "content": "Epithelial cells in the periodontal membrane of teeth with and without periapical inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211246"} {"pmid": "4211248", "title": "Antigenic relationship between pseudomonas Bal-31 membranes and bacteriophage PM2.", "content": "Antigenic relationship between pseudomonas Bal-31 membranes and bacteriophage PM2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211248"} {"pmid": "4211249", "title": "The kinetics of sodium transport in the toad urinary bladder. 3. The role of potassium.", "content": "The kinetics of sodium transport in the toad urinary bladder. 3. The role of potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211249"} {"pmid": "4211251", "title": "Cerebrospinal fluid flow and iodide 131 transport in the spinal subarachnoid space.", "content": "Cerebrospinal fluid flow and iodide 131 transport in the spinal subarachnoid space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211251"} {"pmid": "4211252", "title": "Thyrotropin releasing hormine (TRH): distribution in the brain, blood and urine of the rat.", "content": "Thyrotropin releasing hormine (TRH): distribution in the brain, blood and urine of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211252"} {"pmid": "4211253", "title": "Endplate currents are shortened by octanol: possible role of membrane lipid.", "content": "Endplate currents are shortened by octanol: possible role of membrane lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211253"} {"pmid": "4211247", "title": "Variation in ADH activity in class I and class II strains of Drosophila.", "content": "Variation in ADH activity in class I and class II strains of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211247"} {"pmid": "4211265", "title": "Aflatoxins in foods and feedstuffs. 2. Determination of the aflatoxin B1, B2, G1 And G2 contents in grain crops.", "content": "Aflatoxins in foods and feedstuffs. 2. Determination of the aflatoxin B1, B2, G1 And G2 contents in grain crops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211265"} {"pmid": "4211268", "title": "Quantitation of bovine liver catalase by single radial immunodiffusion.", "content": "Quantitation of bovine liver catalase by single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211268"} {"pmid": "4211269", "title": "Endontics in a capuchin monkey: reduction in the length of the canine crown.", "content": "Endontics in a capuchin monkey: reduction in the length of the canine crown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211269"} {"pmid": "4211271", "title": "High voltage electron microscopy on microgametogenesis of Haemoproteus columbae.", "content": "High voltage electron microscopy on microgametogenesis of Haemoproteus columbae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211271"} {"pmid": "4211272", "title": "'Coupled transglucuronidation': a new tool for studying the latency of UDP-glucuronyl transferase.", "content": "'Coupled transglucuronidation': a new tool for studying the latency of UDP-glucuronyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211272"} {"pmid": "4211751", "title": "A comparative study of human and monkey (Macaca irus) fibrinogen degradation products.", "content": "A comparative study of human and monkey (Macaca irus) fibrinogen degradation products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211751"} {"pmid": "4211752", "title": "A comparative study of the nasal fossa of four nonhuman primates.", "content": "A comparative study of the nasal fossa of four nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211752"} {"pmid": "4211753", "title": "A comparison of anticoagulants for the analysis of glucose concentration and for haematological measurements in bovine blood.", "content": "A comparison of anticoagulants for the analysis of glucose concentration and for haematological measurements in bovine blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211753"} {"pmid": "4211754", "title": "A cytotoxicity assay of Pseudomonas aeruginosa culture filtrates by a dye-uptake test.", "content": "A cytotoxicity assay of Pseudomonas aeruginosa culture filtrates by a dye-uptake test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211754"} {"pmid": "4211755", "title": "A fatal adenovirus infection of broiler chickens: inclusion body hepatitis.", "content": "A fatal adenovirus infection of broiler chickens: inclusion body hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211755"} {"pmid": "4211756", "title": "A microcalorimetric study on the unfolding of E. coli ribosome.", "content": "A microcalorimetric study on the unfolding of E. coli ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211756"} {"pmid": "4211750", "title": "A comparative serological study of Dermatophilus congolensis antigens prepared by different methods.", "content": "A comparative serological study of Dermatophilus congolensis antigens prepared by different methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211750"} {"pmid": "4211758", "title": "A plate-diffusion method for the detection of antistaphylolysin activity in human serum.", "content": "A plate-diffusion method for the detection of antistaphylolysin activity in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211758"} {"pmid": "4211757", "title": "A new R factor from Pseudomonas aeruginosa.", "content": "A new R factor from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211757"} {"pmid": "4211759", "title": "A polyvalent Pseudomonas vaccine.", "content": "A polyvalent Pseudomonas vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211759"} {"pmid": "4211760", "title": "A quick method for calculation of the vascular mean transit time.", "content": "A quick method for calculation of the vascular mean transit time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211760"} {"pmid": "4211762", "title": "A search for radioresistance in experimental populations of Drosophila with radiation histories.", "content": "A search for radioresistance in experimental populations of Drosophila with radiation histories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211762"} {"pmid": "4211764", "title": "A simple apparatus for the continuous monitoring of 14CO2 production from several small reaction mixtures.", "content": "A simple apparatus for the continuous monitoring of 14CO2 production from several small reaction mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211764"} {"pmid": "4211765", "title": "A simple method for accurate assessment of the glomerular filtration rate in children.", "content": "A simple method for accurate assessment of the glomerular filtration rate in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211765"} {"pmid": "4211766", "title": "A study of barrels and pyramidal dendritic clusters in the cerebral cortex.", "content": "A study of barrels and pyramidal dendritic clusters in the cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211766"} {"pmid": "4211761", "title": "A radioimmunoassay for measurement of 3,3',5'-triiodothyronine (reverse T3).", "content": "A radioimmunoassay for measurement of 3,3',5'-triiodothyronine (reverse T3). A highly specific antiserum to 3,3',5'-triiodothyronine (reverse T(3), rT(3)) was prepared by immunization of rabbits with D,L-rT(3)-human serum albumin conjugate. Of the various thyroid hormone derivatives tested, only 3,3'-diiodothyronine (3,3'-T(2)) cross-reacted significantly (10%) with rT(3)-binding sites on the antiserum, while thyroxine (T(4)) and triiodothyronine (T(3)) cross-reacted by less than 0.1%. The antiserum was used in a simple, sensitive, precise, and reproducible radioimmunoassay (RIA) for measurement of rT(3) in ethanolic extracts of serum. The dose-response curves of inhibition of the binding of [(125)I]rT(3) to antibody obtained by serial dilutions of serum extracts were essentially parallel to the standard assay curve. Recovery of nonradioactive rT(3) added to serum before extraction averaged 93%. Serum rT(3) concentrations were found to be (mean+/-SD) 41+/-10 ng/100 ml in 27 normal subjects, 103+/-49 ng/100 ml in 22 hyperthyroid patients, 19+/-9 ng/100 ml in 12 hypothyroid patients, and 54+/-7 ng/100 ml in five subjects with elevated serum thyroxine-binding globulin: the values in each of the latter three groups of individuals were significantly different from normal. Reverse T(3) was detected regularly in normal or supranormal concentrations in serum of 12 hypothyroid patients rendered euthyroid or mildly hyperthyroid by treatment with synthetic T(4). It is suggested that serum rT(3) values noted here should be taken to reflect the relative changes in serum rT(3) rather than its absolute values in health and thyroid disease. True serum rT(3) may be somewhat different because: (a) D.L-rT(3) employed in the standard curve and L-rT(3) present in human serum may react differently with anti-D,L-rT(2). (b) Even though 3,3'-T(2), which cross-reacted 10% in rT(3) RIA, has been considered unlikely to be present in human serum, it may circulate in low levels. (c) Cross-reaction of T(4) in rT(3) RIA of 0.06% although small, could contribute to RIA estimates of rT(2); the effect of T(4) would be particularly important in case of serum of hyperthyroid patients. Thus, serum rT(3) concentration in hyperthyroid patients averaged 89+/-48 mug/100 ml after correction for cross-reaction effects of T(4): this value was about 14% lower than that before correction (see above). Serum rT(3) concentration in cord sera of seven newborns averaged 136+/-19 ng/100 ml; it was clearly elevated and within the range of values seen in hyperthyroid patients. This was the case when the mean T(4) concentration in the newborn cord sera was moderately higher than normal and about one-half that in hyperthyroid patients, whereas serum T(3) was markedly below the normal adult level. A Pronase hydrolysate of thyroglobulin prepared from pooled normal thyroid glands contained 0.042, 3.0, and 0.16 mug/mg protein of rT(3), T(4), and T(3), respectively. The various data suggest that: (a) rT(3) is a normal component of human serum and thyroglobulin: (b) peripheral metabolism of T(4) is an important source of the rT(3) present in serum: (c) peripheral conversion of T(4) to T(3) and rT(3) may not necessarily be a random process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211761"} {"pmid": "4211767", "title": "A study of Mycobacterium fortuitum (ranae).", "content": "A study of Mycobacterium fortuitum (ranae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211767"} {"pmid": "4211768", "title": "A variant of factor 8 related antigen.", "content": "A variant of factor 8 related antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211768"} {"pmid": "4211763", "title": "A simple \"variable blade\" laryngoscope for use in animals.", "content": "A simple \"variable blade\" laryngoscope for use in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211763"} {"pmid": "4211769", "title": "A Clinicopathologic Conference from Veterans Administration Hospital Hines, Illinois: Nephritis-like symptoms progressing to congestive heart failure.", "content": "A Clinicopathologic Conference from Veterans Administration Hospital Hines, Illinois: Nephritis-like symptoms progressing to congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211769"} {"pmid": "4211771", "title": "Accidental nosematosis in mice with impaired immunological competence.", "content": "Accidental nosematosis in mice with impaired immunological competence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211771"} {"pmid": "4211770", "title": "Abnormalities of in vitro thyroid function tests in renal disease.", "content": "Abnormalities of in vitro thyroid function tests in renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211770"} {"pmid": "4211772", "title": "Acetylation of pronase trypsin.", "content": "Acetylation of pronase trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211772"} {"pmid": "4211773", "title": "Acid denaturation of human carbonic anhydrase B. A fluorimetric kinetic study.", "content": "Acid denaturation of human carbonic anhydrase B. A fluorimetric kinetic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211773"} {"pmid": "4211774", "title": "Acidic aqueous extraction of hypothalamic luteinizing hormone releasing hormone to study biological effects.", "content": "Acidic aqueous extraction of hypothalamic luteinizing hormone releasing hormone to study biological effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211774"} {"pmid": "4211775", "title": "Acquired factor-IX inhibitor in a nonhaemophilic patient with autoimmune disease.", "content": "Acquired factor-IX inhibitor in a nonhaemophilic patient with autoimmune disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211775"} {"pmid": "4211776", "title": "Action of flavonoids on blood cells: trimodal action of flavonoids elucidates their inconsistent physiologic effects.", "content": "Action of flavonoids on blood cells: trimodal action of flavonoids elucidates their inconsistent physiologic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211776"} {"pmid": "4211779", "title": "Acute brucellosis with unexpected source.", "content": "Acute brucellosis with unexpected source.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211779"} {"pmid": "4211778", "title": "Activities of neurons in area 3a of the cerebral cortex during voluntary movements in the monkey.", "content": "Activities of neurons in area 3a of the cerebral cortex during voluntary movements in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211778"} {"pmid": "4211781", "title": "Affinity chromatography purification of rat alpha 1-foetoprotein.", "content": "Affinity chromatography purification of rat alpha 1-foetoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211781"} {"pmid": "4211780", "title": "Adjuvants and in vitro antibody production.", "content": "Adjuvants and in vitro antibody production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211780"} {"pmid": "4211782", "title": "Affinity of UDP-glucuronyl-transferase for several substrates and for chloramphenicol.", "content": "Affinity of UDP-glucuronyl-transferase for several substrates and for chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211782"} {"pmid": "4211783", "title": "Albumin and coagulation factor 8 (AHF).", "content": "Albumin and coagulation factor 8 (AHF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211783"} {"pmid": "4211784", "title": "Albumin and creatinine clearances in renal disease.", "content": "Albumin and creatinine clearances in renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211784"} {"pmid": "4211786", "title": "Alteration of vascular permeability in rabbits by culture filtrates of Bacillus cereus and related species.", "content": "Alteration of vascular permeability in rabbits by culture filtrates of Bacillus cereus and related species. Crude culture filtrates of strains of Bacillus cereus, B. thuringiensis, and B. mycoides caused an increase in vascular permeability when injected intradermally into rabbits. The time course of the change in permeability was determined, and could easily be distinguished from a more transient effect induced by purified (from B. cereus) phospholipase C. The properties of the responsible factor were found to be similar to those reported for the guinea pig dermal factor and the ileal loop fluid inducing factor, namely: synthesis by vigorously aerated, logarithmically growing cells; inactivation by heating at 56 C; non-dialyzability; precipitation with ammonium sulfate; and antigenic characteristics. Permeability factor was not related to either the phospholipase C or the hemolysin produced by B. cereus. Activity of this B. cereus toxin, as measured in the vascular permeability and ileal loop assays, can easily be quantitated, but the greater simplicity, reliability, and economy of the vascular permeability test make it the method of choice for screening cultures or following toxin purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211786"} {"pmid": "4211787", "title": "Altered metabolism in a Streptococcus lactis C2 mutant deficient in lactic dehydrogenase.", "content": "Altered metabolism in a Streptococcus lactis C2 mutant deficient in lactic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211787"} {"pmid": "4211777", "title": "Action of metabolic inhibitors on competence and genetic transformation in Bacillus subtilis.", "content": "Action of metabolic inhibitors on competence and genetic transformation in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211777"} {"pmid": "4211789", "title": "Aminoacyl transfer ribonucleic acid synthesis in toluene-treated liver cells.", "content": "Aminoacyl transfer ribonucleic acid synthesis in toluene-treated liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211789"} {"pmid": "4211788", "title": "Altered proteins with triosephosphate isomerase activity in suppressor-containing strains of Bacillus subtilis.", "content": "Altered proteins with triosephosphate isomerase activity in suppressor-containing strains of Bacillus subtilis. Suppressor mutations in Bacillus subtilis cause the synthesis of a new protein with the enzymatic activity of l-leucine dehydrogenase and two groups of new proteins with the activity of triosephosphate isomerase. The new isoenzymes of triosephosphate isomerase are separable by zone electrophoresis and differ among themselves in elution behavior upon gel permeation chromatography. One group has an apparent average molecular weight of 120,000 to 135,000, which is more than twice that of the wild-type enzyme. Another group appears to be even higher in molecular weight. These data are consistent with the working hypothesis that the new isoenzymes are produced by extension of growing polypeptide chains through one or more chain-terminating triplets, although other mechanisms resulting in alteration of shapes, charges, or associations of the enzymes are not excluded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211788"} {"pmid": "4211790", "title": "Aminoglycoside antibiotics. V. The 4'-deoxybutirosins (Bu-1975C1 and C2), new aminoglycoside antibiotics of bacterial origin.", "content": "Aminoglycoside antibiotics. V. The 4'-deoxybutirosins (Bu-1975C1 and C2), new aminoglycoside antibiotics of bacterial origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211790"} {"pmid": "4211791", "title": "An acquired lateral ventricular diverticulum appearing as a positive brain scan.", "content": "An acquired lateral ventricular diverticulum appearing as a positive brain scan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211791"} {"pmid": "4211792", "title": "An acylated mannan in the membrane of Micrococcus lysodeikticus.", "content": "An acylated mannan in the membrane of Micrococcus lysodeikticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211792"} {"pmid": "4211785", "title": "Allergic reactions to a horse globulin therapy and their prevention by induction of immunological tolerance.", "content": "Allergic reactions to a horse globulin therapy and their prevention by induction of immunological tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211785"} {"pmid": "4211794", "title": "An analysis of the efficiency of a Rhesus haemolytic disease prophylaxis programme.", "content": "An analysis of the efficiency of a Rhesus haemolytic disease prophylaxis programme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211794"} {"pmid": "4211795", "title": "An enzymological approach to the lipidoses.", "content": "An enzymological approach to the lipidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211795"} {"pmid": "4211797", "title": "An example of rapid prenatal diagnosis of Fabry's disease using microtechniques.", "content": "An example of rapid prenatal diagnosis of Fabry's disease using microtechniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211797"} {"pmid": "4211798", "title": "An immunological assay for the sigma subunit of RNA polymerase in extracts of vegetative and sporulating Bacillus subtilis.", "content": "An immunological assay for the sigma subunit of RNA polymerase in extracts of vegetative and sporulating Bacillus subtilis. The activity of the sigma subunit of Bacillus subtilis RNA polymerase decreases markedly during the first hours of sporulation [T.G. Linn et al. (1973) Proc. Nat. Acad. Sci. USA 70, 1865-1869]. We have prepared antibody against RNA polymerase holoenzyme to determine the fate of sigma polypeptide during spore formation. This antiserum specifically and independently precipitates sigma and core polymerase from crude extracts of B. subtilis as judged by both sodium dodecyl sulfate and urea gel electrophoresis of the precipitates. We report that crude extracts of sporulating cells lacking sigma activity contain as much sigma polypeptide as extracts of vegetative cells. However, sigma polypeptide in extracts from sporulating cells is apparently only weakly associated with RNA polymerase, as indicated by the failure of sigma to co-purify efficiently with core enzyme during phase partitioning. The loss of sigma activity and the weak binding of sigma to core enzyme occurs normally in a mutant blocked at an intermediate stage of sporulation (SpoII-4Z) and in wild-type bacteria sporulating in 121B medium, Difco sporulation medium, or Sterlini-Mandelstam resuspension medium. In contrast, sigma in two mutants (SpoOa-5NA and SpoOb-6Z) blocked at an early stage of spore formation remains active and tightly associated with RNA polymerase during stationary phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211798"} {"pmid": "4211799", "title": "An improved test for Haemophilus influenzae precipitins in the serum of patients with chronic respiratory disease.", "content": "An improved test for Haemophilus influenzae precipitins in the serum of patients with chronic respiratory disease. The detection of antibacterial precipitins in the serum of patients with chronic lower respiratory infections has been shown to be of great value in the assessment of pathogenicity of the corresponding bacterial species in the sputum. The test used hitherto, however, is time-consuming and cumbersome owing to the need to distinguish, by immunoelectrophoresis, between antibodies specific to the organism in question and those which react with antigens common to various Gram-negative species. A method has now been devised for the preparation of an extract of Haemophilus influenzae containing species-specific antigens only. Use of this extract obviates the need for immuno-electrophoresis and improves the sensitivity of the test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211799"} {"pmid": "4211800", "title": "An introduction to principles of veterinary clinical pharmacology: the elimination of drugs. 2. Mechanisms of drug elimination.", "content": "An introduction to principles of veterinary clinical pharmacology: the elimination of drugs. 2. Mechanisms of drug elimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211800"} {"pmid": "4211793", "title": "An aetiological study of fifty-three female patients from a subnormality hospital and of their offspring.", "content": "An aetiological study of fifty-three female patients from a subnormality hospital and of their offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211793"} {"pmid": "4211801", "title": "An investigation of the efficacy of three Brucella vaccines in cattle.", "content": "An investigation of the efficacy of three Brucella vaccines in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211801"} {"pmid": "4211803", "title": "An unusual expression of Ii antigens in erythrocytes of a healthy adult person.", "content": "An unusual expression of Ii antigens in erythrocytes of a healthy adult person.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211803"} {"pmid": "4211802", "title": "An overview of primary endocardial fibroelastosis and chronic viral cardiomyopathy.", "content": "An overview of primary endocardial fibroelastosis and chronic viral cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211802"} {"pmid": "4211796", "title": "An epidemiologic approach to cancer of the large intestine: the significance of disease relationships.", "content": "An epidemiologic approach to cancer of the large intestine: the significance of disease relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211796"} {"pmid": "4211804", "title": "Anabolic and catabolic routes of arginine metabolism in B. subtilis producing bacitracin.", "content": "Anabolic and catabolic routes of arginine metabolism in B. subtilis producing bacitracin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211804"} {"pmid": "4211806", "title": "Analysis of albumin in meconium for early detection of cystic fibrosis. A methodological study.", "content": "Analysis of albumin in meconium for early detection of cystic fibrosis. A methodological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211806"} {"pmid": "4211807", "title": "Animal bite.", "content": "Animal bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211807"} {"pmid": "4211805", "title": "Anaesthetic molecules.", "content": "Anaesthetic molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211805"} {"pmid": "4211808", "title": "Animal models in psychiatry.", "content": "Animal models in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211808"} {"pmid": "4211809", "title": "Antagonists in the 5-phenyl-benzomorphan series.", "content": "Antagonists in the 5-phenyl-benzomorphan series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211809"} {"pmid": "4211810", "title": "Anti-heart antibodies in chronic cor pulmonale.", "content": "Anti-heart antibodies in chronic cor pulmonale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211810"} {"pmid": "4211811", "title": "Antibody responses in cell cultures from draining and non-draining rabbit lymph nodes primed with native or polymerized human albumin.", "content": "Antibody responses in cell cultures from draining and non-draining rabbit lymph nodes primed with native or polymerized human albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211811"} {"pmid": "4211812", "title": "Antibody to bovine choline acetyltransferase and immunofluorescent localisation of the enzyme in neurones.", "content": "Antibody to bovine choline acetyltransferase and immunofluorescent localisation of the enzyme in neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211812"} {"pmid": "4211813", "title": "Arylpyrrolidines as narcotic antagonists.", "content": "Arylpyrrolidines as narcotic antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211813"} {"pmid": "4211814", "title": "Aspects of experimental hepatocarcinogenesis. 3. Iron overload and hepatocarcinogenesis.", "content": "Aspects of experimental hepatocarcinogenesis. 3. Iron overload and hepatocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211814"} {"pmid": "4211815", "title": "Assaying narcotic-antagonist drugs for analgesic activity in rhesus monkeys.", "content": "Assaying narcotic-antagonist drugs for analgesic activity in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211815"} {"pmid": "4211816", "title": "Assessment of the agonist and antagonist properties of narcotic analgesic drugs by their actions on the morphine receptor in the guinea pig ileum.", "content": "Assessment of the agonist and antagonist properties of narcotic analgesic drugs by their actions on the morphine receptor in the guinea pig ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211816"} {"pmid": "4211817", "title": "Association between histocompatibility type and the ability to make anti-Rh antibodies.", "content": "Association between histocompatibility type and the ability to make anti-Rh antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211817"} {"pmid": "4211818", "title": "Atmospheric transport of polychlorobiphenyls to the North Atlantic.", "content": "Atmospheric transport of polychlorobiphenyls to the North Atlantic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211818"} {"pmid": "4211819", "title": "Attempts to induce mycetoma in monkeys and mice using Madurella mycetomi.", "content": "Attempts to induce mycetoma in monkeys and mice using Madurella mycetomi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211819"} {"pmid": "4211820", "title": "Auditory frequency discrimination in vertebrates.", "content": "Auditory frequency discrimination in vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211820"} {"pmid": "4211822", "title": "Autoimmune pulmonary fibrosis, an experimental model.", "content": "Autoimmune pulmonary fibrosis, an experimental model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211822"} {"pmid": "4211824", "title": "Autoradiographic examinations in the early period of wound healing.", "content": "Autoradiographic examinations in the early period of wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211824"} {"pmid": "4211823", "title": "Autoimmunity in trypanosome infections. I. Tissue autoantibodies in Trypanosoma (Trypanozoon) brucei infections of the rabbit.", "content": "Autoimmunity in trypanosome infections. I. Tissue autoantibodies in Trypanosoma (Trypanozoon) brucei infections of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211823"} {"pmid": "4211825", "title": "Autosomal recessive cerebro-oculo-facio-skeletal (COFS) syndrome.", "content": "Autosomal recessive cerebro-oculo-facio-skeletal (COFS) syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211825"} {"pmid": "4211826", "title": "Axonal transport of phenylethanolamine-N-methyltransferase in toad sciatic nerve.", "content": "Axonal transport of phenylethanolamine-N-methyltransferase in toad sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211826"} {"pmid": "4211827", "title": "ABO blood groups, Rhesus negativity, and primary biliary cirrhosis.", "content": "ABO blood groups, Rhesus negativity, and primary biliary cirrhosis. The distribution of blood groups and Rhesus negativity in 91 British patients with primary biliary cirrhosis was compared with a sample of registered blood donors. There were no significant differences from the expected proportions calculated from the control groups. Although the number of cases studied is small the analysis does not confirm previous reports of an excess of A group in the disease. If a genetic basis exists for primary biliary cirrhosis alternative markers must be found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211827"} {"pmid": "4211821", "title": "Australia antigen and hepatitis,.", "content": "Australia antigen and hepatitis,.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211821"} {"pmid": "4211828", "title": "Bacillus subtilis DNA polymerases.", "content": "Bacillus subtilis DNA polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211828"} {"pmid": "4211829", "title": "Bacterial attack on phenolic ethers. Preliminary studies on systems transporting electrons to the substrate binding components in bacterial O-dealkylases.", "content": "Bacterial attack on phenolic ethers. Preliminary studies on systems transporting electrons to the substrate binding components in bacterial O-dealkylases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211829"} {"pmid": "4211830", "title": "Bacterial calcium transport: energy-dependent calcium uptake by membrane vesicles from Bacillus megaterium.", "content": "Bacterial calcium transport: energy-dependent calcium uptake by membrane vesicles from Bacillus megaterium. Membrane vesicles capable of energy-dependent calcium uptake have been prepared from Bacillus megaterium cells in log-phase growth or when undergoing sporulation. The uptake is dependent on the calcium concentration and appears saturable in vesicles from cells in log-phase growth. Both ascorbate and phenazine methosulfate are needed as a source of electrons for the energy-dependent increase in calcium uptake. Addition of 8 mM sodium cyanide inhibited the energy-dependent uptake. If this calcium uptake mechanism is a component of the sporulation-specific calcium accumulation process, the latter's functional expression would appear to be inhibited during log-phase growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211830"} {"pmid": "4211831", "title": "Bactericidal action of a 2-hydroxy-3-alkyl-1,4-naphthoquinone: blockade of metabolite permeation across the membrane.", "content": "Bactericidal action of a 2-hydroxy-3-alkyl-1,4-naphthoquinone: blockade of metabolite permeation across the membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211831"} {"pmid": "4211832", "title": "Bile production in fasted and fed primates.", "content": "Bile production in fasted and fed primates. Previous experiments have suggested differences in the bile salt independent flow rate between monkeys and dogs, and in the ability of bile salt secretion to influence bile flow. The present study was performed to determine whether the availability of food could have influenced these results. Bile flow and bile salt secretion rates were studied in fasted and fed primates. In the fasting experiments, sodium cholate, sodium taurocholate, and monkey bile were infused into the duodenum; only sodium cholate was infused in the feeding experiments. The results showed that bile flow was linearly related to the bile salt secretion rate in both fasting and feeding animals. Bile salt independent flow is extremely variable during fasting and is increased and stabilized by feeding. These studies indicate that the differences found in previous experiments are probably attributable to variations in experimental design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211832"} {"pmid": "4211833", "title": "Binding of radioactive chinoform to cohn fractions of human serum by equilibrium dialysis.", "content": "Binding of radioactive chinoform to cohn fractions of human serum by equilibrium dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211833"} {"pmid": "4211834", "title": "Bioavailability of indomethacin in man.", "content": "Bioavailability of indomethacin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211834"} {"pmid": "4211835", "title": "Biochemical studies on degenerative neurological disorders. I. Acute experimental encephalitis.", "content": "Biochemical studies on degenerative neurological disorders. I. Acute experimental encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211835"} {"pmid": "4211836", "title": "Biochemistry of drug dependence.", "content": "Biochemistry of drug dependence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211836"} {"pmid": "4211837", "title": "Biochemistry of mammalian fertilization.", "content": "Biochemistry of mammalian fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211837"} {"pmid": "4211838", "title": "Biochemistry of penicillin and cephalosporin fermentations.", "content": "Biochemistry of penicillin and cephalosporin fermentations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211838"} {"pmid": "4211839", "title": "Blood grouping with a miniature Centrifugal Fast Analyzer.", "content": "Blood grouping with a miniature Centrifugal Fast Analyzer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211839"} {"pmid": "4211840", "title": "Blood lymphocytes after radiation therapy of mammary carcinoma.", "content": "Blood lymphocytes after radiation therapy of mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211840"} {"pmid": "4211841", "title": "Brain stem unit activity related to horizontal eye movements occurring during visual tracking.", "content": "Brain stem unit activity related to horizontal eye movements occurring during visual tracking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211841"} {"pmid": "4211842", "title": "Brain to bottle time.", "content": "Brain to bottle time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211842"} {"pmid": "4211843", "title": "Breakdown of pulse-labeled ribonucleic acid and polysomes in Bacillus megaterium: actions of streptolydigin, echinomycin, and triostins.", "content": "Breakdown of pulse-labeled ribonucleic acid and polysomes in Bacillus megaterium: actions of streptolydigin, echinomycin, and triostins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211843"} {"pmid": "4211845", "title": "Brucellosis of the carpus. Report of a case.", "content": "Brucellosis of the carpus. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211845"} {"pmid": "4211844", "title": "Bridged amino tetralins.", "content": "Bridged amino tetralins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211844"} {"pmid": "4211846", "title": "Bursal and postbursal cells in chicken. Separation by gradient centrifugation.", "content": "Bursal and postbursal cells in chicken. Separation by gradient centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211846"} {"pmid": "4211847", "title": "Carbonic anhydrases from human neonatal erythrocytes.", "content": "Carbonic anhydrases from human neonatal erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211847"} {"pmid": "4211848", "title": "Carcinogenicity of bracken and shikimic acid.", "content": "Carcinogenicity of bracken and shikimic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211848"} {"pmid": "4211849", "title": "Carcinoma of the larynx in two patients with keratoacanthoma.", "content": "Carcinoma of the larynx in two patients with keratoacanthoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211849"} {"pmid": "4211850", "title": "Cardiohemodynamic effect of 5-methyl-7-diethyl-amino-s-triazolo-(1,5a)pyrimidine (trapymin).", "content": "Cardiohemodynamic effect of 5-methyl-7-diethyl-amino-s-triazolo-(1,5a)pyrimidine (trapymin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211850"} {"pmid": "4211852", "title": "Care-eliciting behavior in man.", "content": "Care-eliciting behavior in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211852"} {"pmid": "4211851", "title": "Cardiovascular and hematological parameters affected by feeding various polychlorinated biphenyls to the single comb white leghorn cockerel.", "content": "Cardiovascular and hematological parameters affected by feeding various polychlorinated biphenyls to the single comb white leghorn cockerel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211851"} {"pmid": "4211853", "title": "Carnosinase: its presence in Pseudomonas aeruginosa.", "content": "Carnosinase: its presence in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211853"} {"pmid": "4211854", "title": "Carrier protein of iodochloroxyquinoline in the serum.", "content": "Carrier protein of iodochloroxyquinoline in the serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211854"} {"pmid": "4211855", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211855"} {"pmid": "4211856", "title": "Cationic proteins of human granulocytes. II. Separation of the cationic proteins of the granules of leukemic myeloid cells.", "content": "Cationic proteins of human granulocytes. II. Separation of the cationic proteins of the granules of leukemic myeloid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211856"} {"pmid": "4211857", "title": "Cell-mediated cytotoxicity against ectromelia virus-infected target cells. I. Specificity and kinetics.", "content": "Cell-mediated cytotoxicity against ectromelia virus-infected target cells. I. Specificity and kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211857"} {"pmid": "4211858", "title": "Cellular sites of immunoglobulins. V. An immunological study of the human gall bladder.", "content": "Cellular sites of immunoglobulins. V. An immunological study of the human gall bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211858"} {"pmid": "4211859", "title": "Cephacetrile, a new cephalosporin, in the treatment of urinary tract infections.", "content": "Cephacetrile, a new cephalosporin, in the treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211859"} {"pmid": "4211860", "title": "Changes in serum alpha-amylase activity in pigs induced by ethionine intoxication.", "content": "Changes in serum alpha-amylase activity in pigs induced by ethionine intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211860"} {"pmid": "4211862", "title": "Characterization of a calcium-binding IgG myeloma protein.", "content": "Characterization of a calcium-binding IgG myeloma protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211862"} {"pmid": "4211864", "title": "Characterization of several viruses isolated from chickens with inclusion body hepatitis and aplastic anemia.", "content": "Characterization of several viruses isolated from chickens with inclusion body hepatitis and aplastic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211864"} {"pmid": "4211863", "title": "Characterization of persistent Modoc viral infections in Syrian hamsters.", "content": "Characterization of persistent Modoc viral infections in Syrian hamsters. Adult Syrian hamsters were readily infected by intranasal inoculation with Modoc virus. Viremias were detected 2 to 6 days after infection and peak viremia titers (10(6.2) plaque-forming units/ml of blood) occurred 4 days postinoculation. All infected animals developed neutralizing and hemagglutination-inhibiting antibodies by 7 days, and complement-fixing antibodies by 14 days postinoculation. High titers of antibodies persisted for at least 4 months. Modoc virus was recovered from throat swabs at 7 days postinoculation, but not at 14 days or later. Urine samples were positive for virus throughout a 12-week observation period. Isolation of virus from lungs and kidneys of one and three animals, respectively, at 151 to 221 days after inoculation confirmed chronic infection. Viral isolations were made only when organs were cultivated in vitro and were unsuccessful by tests on 10% homogenates of the organs. Horizontal viral transmission of virus by infected hamsters that were viruric was demonstrated in only 1 of 27 normal hamsters that were cocaged for 4 weeks under crowded conditions. General failure to obtain horizontal viral transmission may relate to rapid inactivation of virus in excreted urine. Vertical viral transmission was not demonstrated from five chronically infected female hamsters to their 34 offspring. However, if primary infection occurred during pregnancy, the progeny were either stillborn or died shortly after birth, and thus appeared to represent transplacental viral transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211863"} {"pmid": "4211861", "title": "Characteristics of PRD1, a plasmid-dependent broad host range DNA bacteriophage.", "content": "Characteristics of PRD1, a plasmid-dependent broad host range DNA bacteriophage. Several distinctive properties of PRD1, an icosahedral plasmid-dependent phage, are described. The drug-resistance plasmid-dependent host range of PRD1 extends beyond the P incompatibility group and includes gram-negative bacteria containing plasmids of incompatibility groups N and W. PRD1 phage will infect pseudomonads and Enterobacteriaceae containing either a P or W incompatibility group plasmid. PRD1 adsorbs to the cell wall of R(+) bacteria and thus its infectivity indicates cell wall alterations by these drug-resistance plasmid groups. PRD1 nucleic acid is duplex DNA with an estimated molecular weight of 24 x 10(6). The appearance of PRD1 in electron micrographs is suggestive of lipid content in addition to its buoyant density of 1.348 in CsCl and its sensitivity to chloroform. The latent period of PRD1 varies with the R(+) host bacterial strain used for growth of the phage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211861"} {"pmid": "4211865", "title": "Characterization of the \"pregnancy zone protein\" in relation to other alpha 2-globulins of pregnancy.", "content": "Characterization of the \"pregnancy zone protein\" in relation to other alpha 2-globulins of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211865"} {"pmid": "4211867", "title": "Characterization of two melanins produced by Phialophora verrucosa.", "content": "Characterization of two melanins produced by Phialophora verrucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211867"} {"pmid": "4211868", "title": "Chimeric Drosophila adults produced by transplantation of nuclei into specific regions of fertilized eggs.", "content": "Chimeric Drosophila adults produced by transplantation of nuclei into specific regions of fertilized eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211868"} {"pmid": "4211866", "title": "Characterization of the active transport of chlorotetracycline in staphylococcus aureus by a fluorescence technique.", "content": "Characterization of the active transport of chlorotetracycline in staphylococcus aureus by a fluorescence technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211866"} {"pmid": "4211869", "title": "Chitinase in goat serum. Preliminary purification and characterization.", "content": "Chitinase in goat serum. Preliminary purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211869"} {"pmid": "4211870", "title": "Chlorhexidine resistance in Proteus mirabilis.", "content": "Chlorhexidine resistance in Proteus mirabilis. A total of 104 clinical isolates of Pr. mirabilis from three hospitals were screened for their sensitivity to chlorhexidine. The minimum inhibitory concentrations of the antiseptic for these strains ranged from 10 to 800 mug/ml. Two strains sensitive to 20 mug of chlorhexidine/ml were adapted to resistance by growth in subinhibitory concentrations of the antiseptic, their MIC values increasing to 200 and 800 mug/ml. These derived strains exhibited slightly reduced sensitivity to cetrimide and benzalkonium chloride. The chlorhexidine-resistant clinical isolates also exhibited this partially decreased sensitivity to the quaternary ammonium compounds. Both the chlorhexidine-sensitive and -resistant strains were uniformly sensitive to chloroxylenol (Dettol), glutaraldehyde, and 2-phenoxyethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211870"} {"pmid": "4211872", "title": "Chorismate mutase from Streptomyces. Purification, properties, and subunit structure of the enzyme from Streptomyces aureofaciens Tü 24.", "content": "Chorismate mutase from Streptomyces. Purification, properties, and subunit structure of the enzyme from Streptomyces aureofaciens Tü 24.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211872"} {"pmid": "4211871", "title": "Choice among penicillins and cephalosporins.", "content": "Choice among penicillins and cephalosporins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211871"} {"pmid": "4211873", "title": "Citrate metabolism in Aerobacter cloacae.", "content": "Citrate metabolism in Aerobacter cloacae. Growth of Aerobacter cloacae on citrate either anaerobically or aerobically did not require and was not stimulated by the presence of Na(+) in the medium. Citrate was metabolized anaerobically via the fermentation pathway as evidenced by the (i) presence of oxalacetate decarboxylase, (ii) induction of citrate lyase, and (iii) repression of alpha-ketoglutarate dehydrogenase under anaerobic conditions. Thus, although all the other enzymes of the citric acid cycle were present in anaerobic cells, this pathway was not available for the metabolism of citrate. Citrate was metabolized aerobically via the citric acid cycle, since (i) citrate lyase but not oxalacetate decarboxylase was repressed and (ii) alpha-ketoglutarate dehydrogenase was induced under these conditions. The presence of Na(+) in the medium did not lead to a repression of alpha-ketoglutarate dehydrogenase as in the case of Aerobacter aerogenes. The oxalacetate decarboxylase was a soluble, constitutive enzyme, not activated by Na(+) nor inhibited by avidin. It was slightly inhibited by ethylenediaminetetraacetate but was not stimulated by Mg(2+) or Mn(2+). Thus, this enzyme differed markedly in its properties from the same enzyme found in citrate-grown A. aerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211873"} {"pmid": "4211874", "title": "Classical and alternate pathway activation of complement in pemphigus vulgaris lesions.", "content": "Classical and alternate pathway activation of complement in pemphigus vulgaris lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211874"} {"pmid": "4211875", "title": "Clinical and immunologic response to bacteria isolated from tracheal secretions following tracheostomy.", "content": "Clinical and immunologic response to bacteria isolated from tracheal secretions following tracheostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211875"} {"pmid": "4211876", "title": "Clinical experience with clonazepam (Rivotril) in the treatment of epilepsy in adults.", "content": "Clinical experience with clonazepam (Rivotril) in the treatment of epilepsy in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211876"} {"pmid": "4211877", "title": "Cofactor investigation of bovine plasma amine oxidase. NaBH4 reduction of enzyme-substrate mixture.", "content": "Cofactor investigation of bovine plasma amine oxidase. NaBH4 reduction of enzyme-substrate mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211877"} {"pmid": "4211878", "title": "Comparative anatomical studies on the mamillary body of mammals.", "content": "Comparative anatomical studies on the mamillary body of mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211878"} {"pmid": "4211879", "title": "Comparative aspects of mammary tumors.", "content": "Comparative aspects of mammary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211879"} {"pmid": "4211880", "title": "Comparative biochemistry of p-hydroxymethyl-L-phenylalanine: in vivo studies.", "content": "Comparative biochemistry of p-hydroxymethyl-L-phenylalanine: in vivo studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211880"} {"pmid": "4211881", "title": "Comparison of pharmacological responses to nicotine and release of catecholamines from the adrenals in dogs and monkeys.", "content": "Comparison of pharmacological responses to nicotine and release of catecholamines from the adrenals in dogs and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211881"} {"pmid": "4211882", "title": "Computer-assisted pediatric hyperalimentation.", "content": "Computer-assisted pediatric hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211882"} {"pmid": "4211883", "title": "Concepts of louse-borne typhus control in developing countries: the use of the living attenuated E strain typhus vaccine in epidemic and endemic situations.", "content": "Concepts of louse-borne typhus control in developing countries: the use of the living attenuated E strain typhus vaccine in epidemic and endemic situations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211883"} {"pmid": "4211884", "title": "Concomitant decrease of the effects of thyroxin on TRH-induced TSH release, and of the pituitary content of triiodothyronine in animals on propylthiouracil.", "content": "Concomitant decrease of the effects of thyroxin on TRH-induced TSH release, and of the pituitary content of triiodothyronine in animals on propylthiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211884"} {"pmid": "4211885", "title": "Cone spectral sensitivity studied with an ERG method.", "content": "Cone spectral sensitivity studied with an ERG method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211885"} {"pmid": "4211886", "title": "Conference on beta cell function, transplantation, and implantable glucose sensors: a summary.", "content": "Conference on beta cell function, transplantation, and implantable glucose sensors: a summary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211886"} {"pmid": "4211887", "title": "Conformational changes of histones and DNA during the thermal denaturation of nucleoprotein.", "content": "Conformational changes of histones and DNA during the thermal denaturation of nucleoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211887"} {"pmid": "4211889", "title": "Continuing dental education using closed circuit television.", "content": "Continuing dental education using closed circuit television.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211889"} {"pmid": "4211888", "title": "Conformational studies of the unfolding of E. coli ribosome.", "content": "Conformational studies of the unfolding of E. coli ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211888"} {"pmid": "4211891", "title": "Control of gene expression in prokaryotic systems.", "content": "Control of gene expression in prokaryotic systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211891"} {"pmid": "4211890", "title": "Continuous intravenous infusion of small doses of insulin in treatment of diabetic ketoacidosis.", "content": "Continuous intravenous infusion of small doses of insulin in treatment of diabetic ketoacidosis. Continuous intravenous infusion of small amounts of insulin has been used in the management of a series of patients with diabetic ketoacidosis. In 13 patients with a plasma glucose level on admission of 725 mg/100 ml (+/- 80 S.E. of mean) and an arterial pH of 7.07 +/- 0.05 a mean loading dose of 6.5 +/- 0.82 units of soluble insulin was administered intravenously, and thereafter a sustaining infusion of 6.5 +/- 0.82 U/hr was continued until ketosis was corrected and the plasma glucose fell below 300 mg/100 ml. The total insulin dose needed to achieve this was 39.2 +/- 6.6 units given over a 3 to 10-hour period. Plasma insulin was measured in patients who had not previously received insulin and the mean level at an infusion rate of 4 U/hr was 75.6 +/- 8.0 muU/ml. Plasma glucose fell at a regular rate of 101 +/- 11 mg/100 ml/hr, and ketosis improved in parallel. Plasma potassium was well maintained throughout treatment. This regimen of treatment was clinically effective and simple to follow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211890"} {"pmid": "4211892", "title": "Conventional and dual competitive binding analyses of thyroxine using the Thyopac-4 kit.", "content": "Conventional and dual competitive binding analyses of thyroxine using the Thyopac-4 kit. A simple method is described for the simultaneous determinations of thyroxine and the effective thyroxine ratio (ETR) using a single kit of Thyopac-4. Thyopac ETR values obtained were 1.00 +/- 0.03 for normal subjects; 1.22 +/- 0.11 for hyperthyroid; 0.87 +/- 0.04 for hypothyroid; and 1.02 +/- 0.05 for pregnant women. Cases with TBG deficiency and the nephrotic syndrome indicated normal values. The value (x) was correlated significantly (gamma = + 0.961) with the free Thyopac index (y), representing a regression equation of y = 71.7x(2) - 88.4x + 24.2. Thyopac ETR was shown to be useful in differentiating normal thyroid states from abnormal, irrespective of changes in T(4)-binding globulin (TBG). Further, the T(4) value obtained simultaneously made it possible to detect changes in the TBG level by noting an inconsistent value for the effective thyroxine ratio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211892"} {"pmid": "4211893", "title": "Correlations between pantothenate uptake, phospholipid synthesis and pantothenate-binding protein formation in Pseudomonas fluorescens P-2.", "content": "Correlations between pantothenate uptake, phospholipid synthesis and pantothenate-binding protein formation in Pseudomonas fluorescens P-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211893"} {"pmid": "4211895", "title": "Counting the cost.", "content": "Counting the cost.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211895"} {"pmid": "4211894", "title": "Correlations between quantitative assay of red cell-bound C3, serologic reactions, and hemolytic anemia.", "content": "Correlations between quantitative assay of red cell-bound C3, serologic reactions, and hemolytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211894"} {"pmid": "4211896", "title": "Cross-linking reactions of lamprey fibrinogen and fibrin.", "content": "Cross-linking reactions of lamprey fibrinogen and fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211896"} {"pmid": "4211897", "title": "Current status of toxicity investigations.", "content": "Current status of toxicity investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211897"} {"pmid": "4211898", "title": "Cystoid degeneration of the macula with hole formation in a baboon.", "content": "Cystoid degeneration of the macula with hole formation in a baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211898"} {"pmid": "4211899", "title": "Cytogenetic effects of environmental mutagens in mammalian cells and the extrapolation to man.", "content": "Cytogenetic effects of environmental mutagens in mammalian cells and the extrapolation to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211899"} {"pmid": "4211900", "title": "Cytogenetic investigation of the Rhnull phenotype.", "content": "Cytogenetic investigation of the Rhnull phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211900"} {"pmid": "4211902", "title": "Deficiency of a carbonic anhydrase (CAI) isoenzyme in the chinchilla.", "content": "Deficiency of a carbonic anhydrase (CAI) isoenzyme in the chinchilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211902"} {"pmid": "4211901", "title": "D-penicillamine therapy of neonatal hyperbilirubinaemia.", "content": "D-penicillamine therapy of neonatal hyperbilirubinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211901"} {"pmid": "4211904", "title": "Degeneration of mouse pancreatic acinar cells during fasting.", "content": "Degeneration of mouse pancreatic acinar cells during fasting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211904"} {"pmid": "4211905", "title": "Demonstration by immunodiffusion agar-gel test of Borrelia anserina antigen in the organs of infected chickens.", "content": "Demonstration by immunodiffusion agar-gel test of Borrelia anserina antigen in the organs of infected chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211905"} {"pmid": "4211906", "title": "Demonstration of indolaminergic fibres in the media eminence of the duck, rat and monkey.", "content": "Demonstration of indolaminergic fibres in the media eminence of the duck, rat and monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211906"} {"pmid": "4211907", "title": "Demonstration of two kinds of thyroglobulin-related proteins bound on microsomes of hog thyroid.", "content": "Demonstration of two kinds of thyroglobulin-related proteins bound on microsomes of hog thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211907"} {"pmid": "4211908", "title": "Dentition of Brachyteles arachnoides with reference to Alouattine and Atelinine affinities.", "content": "Dentition of Brachyteles arachnoides with reference to Alouattine and Atelinine affinities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211908"} {"pmid": "4211909", "title": "Denturism--again.", "content": "Denturism--again.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211909"} {"pmid": "4211910", "title": "Deoxyribonucleic acid polymerase 3 (Escherichia coli K12).", "content": "Deoxyribonucleic acid polymerase 3 (Escherichia coli K12).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211910"} {"pmid": "4211912", "title": "Detection of Australia-SH antigen in serum. A comparison of the electron microscopical, agar gel double diffusion, and complement fixation tests.", "content": "Detection of Australia-SH antigen in serum. A comparison of the electron microscopical, agar gel double diffusion, and complement fixation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211912"} {"pmid": "4211903", "title": "Defining the clinical problem of massive rectal bleeding.", "content": "Defining the clinical problem of massive rectal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211903"} {"pmid": "4211913", "title": "Detection of Escherichia coli antigens by a latex agglutination test.", "content": "Detection of Escherichia coli antigens by a latex agglutination test. A latex particle agglutination technique to detect ethylenediaminetetraacetate-solubilized extracts from Escherichia coli and whole E. coli cells is described. The sensitivity of the serological test was found to be 0.5 to 2.5 ng for the solubilized antigens and 1.5 x 10(6) to 5.7 x 10(6) cells per ml for the particulate antigens. The test was 100 to 1,000 times more sensitive than the standard bacterial agglutination test. Furthermore, it detected E. coli antigens during all phases of bacterial growth, whereas the bacterial test detected the antigens only after the mid-log phase. No significant cross-reactivity was observed between latex-anti-E. coli preparations and heterologous bacterial strains used in the experimental procedure. A buffer formula containing fatty acid-free bovine albumin prevented nonspecific aggregation of the latex particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211913"} {"pmid": "4211915", "title": "Determination of disodium edetate dihydrate in streptomycin by atomic absorption spectrophotometry.", "content": "Determination of disodium edetate dihydrate in streptomycin by atomic absorption spectrophotometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211915"} {"pmid": "4211914", "title": "Detergents.", "content": "Detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211914"} {"pmid": "4211916", "title": "Determination of organ volume by means of ultrasonic B-mode scanning.", "content": "Determination of organ volume by means of ultrasonic B-mode scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211916"} {"pmid": "4211917", "title": "Determination of thyroid volume by ultrasonic scanning.", "content": "Determination of thyroid volume by ultrasonic scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211917"} {"pmid": "4211919", "title": "Development and behaviour of a strain of bovine ephemeral fever virus with unusual host range.", "content": "Development and behaviour of a strain of bovine ephemeral fever virus with unusual host range.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211919"} {"pmid": "4211918", "title": "Detoxication of carboxin.", "content": "Detoxication of carboxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211918"} {"pmid": "4211921", "title": "Development of the hypothalamohypophysial unit in the chick.", "content": "Development of the hypothalamohypophysial unit in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211921"} {"pmid": "4211920", "title": "Development and evaluation of an inhalation aerosol of nitroglycerin.", "content": "Development and evaluation of an inhalation aerosol of nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211920"} {"pmid": "4211911", "title": "Detection of antibodies to Campylobacter fetus (Vibrio fetus) in the preputial secretions of bulls with vibriosis.", "content": "Detection of antibodies to Campylobacter fetus (Vibrio fetus) in the preputial secretions of bulls with vibriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211911"} {"pmid": "4211922", "title": "Development of Sarcocystis fusiformis in the small intestine of the dog.", "content": "Development of Sarcocystis fusiformis in the small intestine of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211922"} {"pmid": "4211923", "title": "Diagnosis of gonorrhoea in women. Role of the rectal sample.", "content": "Diagnosis of gonorrhoea in women. Role of the rectal sample.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211923"} {"pmid": "4211924", "title": "Diazepam prevents and aborts lidocaine convulsions in monkeys.", "content": "Diazepam prevents and aborts lidocaine convulsions in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211924"} {"pmid": "4211925", "title": "Differences in acute and convalescent-phase antibodies of cats infected with feline picornaviruses.", "content": "Differences in acute and convalescent-phase antibodies of cats infected with feline picornaviruses. Complement fixation inhibiting and complement-fixing antibodies were demonstrated in sera from cats during the acute and convalescent stages, respectively, of feline picornavirus infections. Complement-fixing antibody activity was present in 19S and 7S globulins, whereas complement fixation inhibiting antibody activity was confined to the 7S globulins. Sera with complement-fixing antibody and sera with complement fixation inhibiting antibody were also shown to have neutralizing and precipitating antibodies. In a study of antibody responses to homotypic and heterotypic strains of feline picornavirus, less serological cross-reactions were observed between strains of feline picornavirus in sera from cats in the acute phase of feline picornavirus infection than in the convalescent phase. The temporal relationship of complement fixation inhibiting and complement-fixing antibody responses of cats after acute viral respiratory infections is contrasted with previously observed antibody response in cats to feline leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211925"} {"pmid": "4211926", "title": "Differentiation and characterization of isomeric polychlorinated biphenyls by gas-liquid chromatography coupled with electron impact and chemical ionization mass spectrometry.", "content": "Differentiation and characterization of isomeric polychlorinated biphenyls by gas-liquid chromatography coupled with electron impact and chemical ionization mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211926"} {"pmid": "4211927", "title": "Diphtheria.", "content": "Diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211927"} {"pmid": "4211929", "title": "Diseases of the oral mucosa.", "content": "Diseases of the oral mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211929"} {"pmid": "4211930", "title": "Disruption of social behaviour of vervet monkeys (Cercopithecus) by low doses of amphetamines.", "content": "Disruption of social behaviour of vervet monkeys (Cercopithecus) by low doses of amphetamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211930"} {"pmid": "4211928", "title": "Discussion paper: antibiotic-sensitive mutants of Escherichia coli possess altered outer membranes.", "content": "Discussion paper: antibiotic-sensitive mutants of Escherichia coli possess altered outer membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211928"} {"pmid": "4211931", "title": "Disseminated mastocytoma and mastocytemia in a dog.", "content": "Disseminated mastocytoma and mastocytemia in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211931"} {"pmid": "4211932", "title": "Distribution and concentration of TRH in the rat brain.", "content": "Distribution and concentration of TRH in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211932"} {"pmid": "4211933", "title": "Distribution of lipase in the digestive system of two teleost fishes.", "content": "Distribution of lipase in the digestive system of two teleost fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211933"} {"pmid": "4211934", "title": "Distribution of pentazocine in blood and brain of the baboon following intravenous injection.", "content": "Distribution of pentazocine in blood and brain of the baboon following intravenous injection. 1 In the baboon the blood levels of pentazocine between 1 and 60 min after intravenous injection of 0.5 mg/kg were measured by a gas chromatographic technique. From cerebral arteriovenous differences it was shown that the peak of the brain concentration occurred within 15 min and probably within 10 min of intravenous injection. At the time of peak concentration about 10% of the injected dose was in the brain, while the corresponding value at 60 min was 2%.2 The concentration of pentazocine in the brain was an order of magnitude greater than the concentration in cerebral venous blood both at 5 min and 60 min after injection. No major brain interregional differences were demonstrated. Cerebrospinal fluid from the cisterna magna did not yield values from which the cerebral concentration of pentazocine could be predicted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211934"} {"pmid": "4211936", "title": "Dose distributions modified by narrow field scanning method in high-energy electron-beam therapy.", "content": "Dose distributions modified by narrow field scanning method in high-energy electron-beam therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211936"} {"pmid": "4211935", "title": "Dithiothreitol-dependent antilisterial activity of lysates from normal macrophages exposed in vitro to culture fluids from spleen cells of BCG-immunized mice.", "content": "Dithiothreitol-dependent antilisterial activity of lysates from normal macrophages exposed in vitro to culture fluids from spleen cells of BCG-immunized mice. The effect of culture fluids from mouse lymphocytes on the antilisterial activity of normal macrophages in vitro was determined. Titers of lysates of macrophages incubated with or without culture fluids from lymphocytes from control mice had titers of 10 to 270 with or without a reducing agent, dithiothreitol. Lysates of macrophages after incubation with culture fluids of spleen lymphocytes from BCG-immunized mice had antilisterial titers with and without dithiothreitol of 197,000 and 810, respectively. This may indicate a dithiothreitol-dependent antilisterial system inherent in activated macrophages of cell-mediated immunity. Lysates of incubated spleen cells and their culture fluids also had slight antilisterial activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211935"} {"pmid": "4211937", "title": "Double gel diffusion studies on Pseudomonas aeruginosa O antigens.", "content": "Double gel diffusion studies on Pseudomonas aeruginosa O antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211937"} {"pmid": "4211938", "title": "Duodenal perforation: a complication of neonatal nasojejunal feeding.", "content": "Duodenal perforation: a complication of neonatal nasojejunal feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211938"} {"pmid": "4211939", "title": "Dynamic aspects of the interaction between antibodies and complement at the cell surface.", "content": "Dynamic aspects of the interaction between antibodies and complement at the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211939"} {"pmid": "4211941", "title": "Dynamics of glomerular ultrafiltration. VI. Studies in the primate.", "content": "Dynamics of glomerular ultrafiltration. VI. Studies in the primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211941"} {"pmid": "4211942", "title": "Early protein-calorie malnutrition in slum areas of Bangkok Municipality, 1970-71.", "content": "Early protein-calorie malnutrition in slum areas of Bangkok Municipality, 1970-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211942"} {"pmid": "4211943", "title": "Ecdysone levels during metamorphosis of Drosophila melanogaster.", "content": "Ecdysone levels during metamorphosis of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211943"} {"pmid": "4211944", "title": "Echographic evaluation of abdominal tumor regression during antineoplastic treatment.", "content": "Echographic evaluation of abdominal tumor regression during antineoplastic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211944"} {"pmid": "4211946", "title": "Editorial: Open system in name only?", "content": "Editorial: Open system in name only?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211946"} {"pmid": "4211945", "title": "Editorial: Ischemia and the gastric mucosal barrier: a note of caution.", "content": "Editorial: Ischemia and the gastric mucosal barrier: a note of caution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211945"} {"pmid": "4211948", "title": "Editorial: Primary care defined; Educational development needed.", "content": "Editorial: Primary care defined; Educational development needed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211948"} {"pmid": "4211947", "title": "Editorial: Optimism in the control of atherosclerosis.", "content": "Editorial: Optimism in the control of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211947"} {"pmid": "4211949", "title": "Editorial: Prostheses for the blind.", "content": "Editorial: Prostheses for the blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211949"} {"pmid": "4211950", "title": "Editorial: The hypothalamic hypophysiotropic thyrotropin releasing hormone (TRH).", "content": "Editorial: The hypothalamic hypophysiotropic thyrotropin releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211950"} {"pmid": "4211940", "title": "Dynamics and control mechanisms in maintenance of regional cerebral blood flow.", "content": "Dynamics and control mechanisms in maintenance of regional cerebral blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211940"} {"pmid": "4211951", "title": "Effect of aflatoxin on serum proteins, complement activity, and the antibody response to Brucella abortus in guinea pigs.", "content": "Effect of aflatoxin on serum proteins, complement activity, and the antibody response to Brucella abortus in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211951"} {"pmid": "4211952", "title": "Effect of boric acid on the catalytic activity of Streptomyces griseus protease 3.", "content": "Effect of boric acid on the catalytic activity of Streptomyces griseus protease 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211952"} {"pmid": "4211953", "title": "Effect of chrysene and carbon tetrachloride administration on rat hepatic microsomal monooxygenase and UDPglucuronosyltransferase activity.", "content": "Effect of chrysene and carbon tetrachloride administration on rat hepatic microsomal monooxygenase and UDPglucuronosyltransferase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211953"} {"pmid": "4211954", "title": "Effect of dextranase on plaque formation in Macaca mulata.", "content": "Effect of dextranase on plaque formation in Macaca mulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211954"} {"pmid": "4211955", "title": "Effect of dietary energy vs. protein restriction on blood constituents and reproductive performance in swine.", "content": "Effect of dietary energy vs. protein restriction on blood constituents and reproductive performance in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211955"} {"pmid": "4211957", "title": "Effect of exercise on platelet count, adhesion, and aggregation.", "content": "Effect of exercise on platelet count, adhesion, and aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211957"} {"pmid": "4211956", "title": "Effect of estrogens at high dosage on the human endometrium.", "content": "Effect of estrogens at high dosage on the human endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211956"} {"pmid": "4211958", "title": "Effect of fentanyl on pendular rotation nystagmus in squirrel monkeys.", "content": "Effect of fentanyl on pendular rotation nystagmus in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211958"} {"pmid": "4211959", "title": "Effect of ischemia on hepatic parenchymal and reticuloendothelial function in the baboon.", "content": "Effect of ischemia on hepatic parenchymal and reticuloendothelial function in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211959"} {"pmid": "4211961", "title": "Effect of pH on potential difference and short circuit current in the isolated human cornea.", "content": "Effect of pH on potential difference and short circuit current in the isolated human cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211961"} {"pmid": "4211960", "title": "Effect of ouabain on sodium transport across hormone-stimulated toad bladder and skin.", "content": "Effect of ouabain on sodium transport across hormone-stimulated toad bladder and skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211960"} {"pmid": "4211962", "title": "Effect of pH on the catalytic activity of Streptomyces griseus protease 3.", "content": "Effect of pH on the catalytic activity of Streptomyces griseus protease 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211962"} {"pmid": "4211963", "title": "Effect of spermidine on morphogenesis in Myxococcus fulvus.", "content": "Effect of spermidine on morphogenesis in Myxococcus fulvus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211963"} {"pmid": "4211964", "title": "Effect of the herbicide N-phosphonomethylglycine on the biosynthesis of aromatic amino acids.", "content": "Effect of the herbicide N-phosphonomethylglycine on the biosynthesis of aromatic amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211964"} {"pmid": "4211965", "title": "Effective treatment of gonorrhoea in London with two oral doses of amoxycillin.", "content": "Effective treatment of gonorrhoea in London with two oral doses of amoxycillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211965"} {"pmid": "4211966", "title": "Effects of anesthetics on cerebral, renal, and splanchnic circulations: recent developments.", "content": "Effects of anesthetics on cerebral, renal, and splanchnic circulations: recent developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211966"} {"pmid": "4211967", "title": "Effects of carbaryl on mouse organs of reproduction.", "content": "Effects of carbaryl on mouse organs of reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211967"} {"pmid": "4211968", "title": "Effects of chemically pure chlorobiphenyls on the morphology of rat liver.", "content": "Effects of chemically pure chlorobiphenyls on the morphology of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211968"} {"pmid": "4211969", "title": "Effects of diphenylamine on sodium and water transport across the toad skin and bladder.", "content": "Effects of diphenylamine on sodium and water transport across the toad skin and bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211969"} {"pmid": "4211970", "title": "Effects of glucocorticoids on TRH and TSH secretion: dose and time considerations.", "content": "Effects of glucocorticoids on TRH and TSH secretion: dose and time considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211970"} {"pmid": "4211971", "title": "Effects of high-dose medroxyprogesterone given for endometrial carcinoma on serum proteins.", "content": "Effects of high-dose medroxyprogesterone given for endometrial carcinoma on serum proteins. 29 women with endometrial cancer were treated with 50-mg medroxyprogesterone twice daily for 1 year and studied to determine what effect this dose of progesterone had on serum proteins. Total serum proteins were significantly (p less than .01) elevated at 3 months until 6 months after treatment. There was a transient decline in albumin at 1 month (p less than .01) which reelevated after 3 months. Alpha-1-globulin and alpha-2-globulin increased at the beginning of therapy (p less than .001 at 1 month) and returned to pretreatment levels at the end of therapy. Gamma globulin levels were significantly less after 1 year of therapy. Alpha-1-acid-glycoprotein was significantly elevated at 1 month and returned to normal after therapy ended. These protein levels are compared with those in pregnancy and during oral contraceptive therapy. It is concluded that these changes are smaller and even the reverse of those seen in pregnancy and oral contraceptive therapy; the changes are attributed to the effect of sex hormones on hepatic metabolic activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211971"} {"pmid": "4211973", "title": "Effects of listerial hemolysin on perfused isolated rat hearts.", "content": "Effects of listerial hemolysin on perfused isolated rat hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211973"} {"pmid": "4211972", "title": "Effects of hypophysectomy of liver donor on net synthesis of specific plasma proteins by the isolated perfused rat liver. Modulation of synthesis of albumin, fibrinogen, alpha 1-acid glycoprotein, alpha 2-(acute phase)-globulin, and haptoglobin by insulin, cortisol, triiodothyronine, and growth hormone.", "content": "Effects of hypophysectomy of liver donor on net synthesis of specific plasma proteins by the isolated perfused rat liver. Modulation of synthesis of albumin, fibrinogen, alpha 1-acid glycoprotein, alpha 2-(acute phase)-globulin, and haptoglobin by insulin, cortisol, triiodothyronine, and growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211972"} {"pmid": "4211974", "title": "Effects of stress on the results of glucose tolerance tests performed on vervet monkeys (Cercopithecus pygerythrus F. Cuvier).", "content": "Effects of stress on the results of glucose tolerance tests performed on vervet monkeys (Cercopithecus pygerythrus F. Cuvier).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211974"} {"pmid": "4211975", "title": "Effects of CI 744 on skeletal muscle activity in monkeys (Macaca mulatta).", "content": "Effects of CI 744 on skeletal muscle activity in monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211975"} {"pmid": "4211976", "title": "Electron microscopic observations of Pseudomonas aeruginosa.", "content": "Electron microscopic observations of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211976"} {"pmid": "4211977", "title": "Elevated alpha1-Antitrypsin serum levels in lung cancer patients.", "content": "Elevated alpha1-Antitrypsin serum levels in lung cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211977"} {"pmid": "4211978", "title": "Embryonic defects in Drosophila eggs after partial u.v. irradiation at different wavelengths.", "content": "Embryonic defects in Drosophila eggs after partial u.v. irradiation at different wavelengths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211978"} {"pmid": "4211979", "title": "Embryonic pole cells and mycoplasmalike symbionts in Drosophila paulistorum.", "content": "Embryonic pole cells and mycoplasmalike symbionts in Drosophila paulistorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211979"} {"pmid": "4211980", "title": "Embryotoxic and teratogenic effect of actinomycin D in the Syrian hamster.", "content": "Embryotoxic and teratogenic effect of actinomycin D in the Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211980"} {"pmid": "4211981", "title": "Employing mentally retarded ex-residents in the institution.", "content": "Employing mentally retarded ex-residents in the institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211981"} {"pmid": "4211982", "title": "Endoscopic removal of a knotted feeding tube from an infant.", "content": "Endoscopic removal of a knotted feeding tube from an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211982"} {"pmid": "4211983", "title": "Endosymbionts: factors on egg pattern formation.", "content": "Endosymbionts: factors on egg pattern formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211983"} {"pmid": "4211984", "title": "Enhancement of hepatic microsomal drug oxidation and glucuronidation in rat by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).", "content": "Enhancement of hepatic microsomal drug oxidation and glucuronidation in rat by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211984"} {"pmid": "4211986", "title": "Enterocutaneous fistula. The \"new look\".", "content": "Enterocutaneous fistula. The \"new look\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211986"} {"pmid": "4211985", "title": "Enhancement of tumour growth by lymphoid cells from mice treated with antilymphocyte globulin.", "content": "Enhancement of tumour growth by lymphoid cells from mice treated with antilymphocyte globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211985"} {"pmid": "4211987", "title": "Enzymatic characterization of sucrose-gradient microbodies of dark-grown, greening and continuously light-grown Euglena gracilis.", "content": "Enzymatic characterization of sucrose-gradient microbodies of dark-grown, greening and continuously light-grown Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211987"} {"pmid": "4211988", "title": "Enzyme activity of spermatozoa from the ductus deferens of inbred mice.", "content": "Enzyme activity of spermatozoa from the ductus deferens of inbred mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211988"} {"pmid": "4211989", "title": "Epidemiology of large bowel disease: the role of fibre.", "content": "Epidemiology of large bowel disease: the role of fibre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211989"} {"pmid": "4211991", "title": "Estimation of the number and size of ribosomal proteins by two-dimensional gel electrophoresis.", "content": "Estimation of the number and size of ribosomal proteins by two-dimensional gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211991"} {"pmid": "4211990", "title": "Estimation of chronic dopamine release from the caudate nucleus of the Macaca mulatta.", "content": "Estimation of chronic dopamine release from the caudate nucleus of the Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211990"} {"pmid": "4211992", "title": "Evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys.", "content": "Evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211992"} {"pmid": "4211993", "title": "Evaluation of effects of cytosine arabinoside on Herpesvirus saimiri replication in owl monkey kidney cells.", "content": "Evaluation of effects of cytosine arabinoside on Herpesvirus saimiri replication in owl monkey kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211993"} {"pmid": "4211998", "title": "Experimental anesthetization of a dromedary camel.", "content": "Experimental anesthetization of a dromedary camel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211998"} {"pmid": "4211997", "title": "Experimental alterations of prolactin levels in goat milk and blood plasma.", "content": "Experimental alterations of prolactin levels in goat milk and blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211997"} {"pmid": "4211995", "title": "Evidence for an unusual immunological response to isopentenyladenosine in rabbits.", "content": "Evidence for an unusual immunological response to isopentenyladenosine in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211995"} {"pmid": "4211994", "title": "Evaluation of topical povidone-iodine ointment in experimental burn wound sepsis.", "content": "Evaluation of topical povidone-iodine ointment in experimental burn wound sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211994"} {"pmid": "4212002", "title": "Experimental malnutrition of neurons and glial cells in vitro. II. Activation of lysosomes and cell death.", "content": "Experimental malnutrition of neurons and glial cells in vitro. II. Activation of lysosomes and cell death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212002"} {"pmid": "4212001", "title": "Experimental malnutrition of neurons and glial cells in vitro. I. First stages of degeneration.", "content": "Experimental malnutrition of neurons and glial cells in vitro. I. First stages of degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212001"} {"pmid": "4212003", "title": "Experimental studies on the nucleus cervicalis lateralis (NCL) of Macaca cyclopis (Swinhoe). II. The spinal afferents to the nucleus cervicalis lateralis in the monkey.", "content": "Experimental studies on the nucleus cervicalis lateralis (NCL) of Macaca cyclopis (Swinhoe). II. The spinal afferents to the nucleus cervicalis lateralis in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212003"} {"pmid": "4211999", "title": "Experimental hepatic porphyria induced by polychlorinated biphenyls.", "content": "Experimental hepatic porphyria induced by polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211999"} {"pmid": "4212004", "title": "Experimentally induced aberrations in the pattern of differentiation in the cellular slime mould Dictyostelium discoideum.", "content": "Experimentally induced aberrations in the pattern of differentiation in the cellular slime mould Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212004"} {"pmid": "4212000", "title": "Experimental listeria monocytogenes-lymphadenitis. Pathohistological observations.", "content": "Experimental listeria monocytogenes-lymphadenitis. Pathohistological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212000"} {"pmid": "4212006", "title": "Extracellular space in some isolated tissues.", "content": "Extracellular space in some isolated tissues. 1. The spaces occupied by isotopically labelled inulin, polyethylene glycol, mol. wt. 4000 (PEG 4000), polyethylene glycol, mol. wt. 1000 (PEG 1000) and sucrose in metabolizing mammalian kidney and liver slices and in toad bladder epithelial cell preparations incubated in vitro have been examined.2. In slices of mammalian tissue, and in homogenized liver, it proved impossible to extract inulin completely from tissue which had been dried. However, inulin was recovered as completely from both dried and undried toad bladder epithelial cells scraped from hemibladders incubated in vitro.3. PEG 4000 occupied a space in all preparations similar to that from which inulin was extracted in dried tissue.4. PEG 1000 and sucrose entered cellular water in mammalian slices, but PEG 1000 occupied a similar space to inulin in toad bladder epithelial cell preparations.6. It is concluded that inulin enters cellular water in mammalian slices from which after drying of the slices it cannot be extracted. It thus rather fortuitously provides a measure of extracellular water under these conditions. In preparations of toad bladder epithelial cells inulin seems to be a satisfactory extracellular marker. PEG 4000, which did not appear to enter cellular water also allows a reasonable estimate of extracellular water. PEG 1000 is a suitable extracellular marker for toad bladder epithelial cell preparations but not for mammalian slices. Sucrose entered cellular water in both slices and toad bladder epithelial cells and is not a satisfactory extracellular marker in these tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212006"} {"pmid": "4212007", "title": "Extraction and purification of kanamycin inactivation enzyme of escherichia coli K12 ML1629.", "content": "Extraction and purification of kanamycin inactivation enzyme of escherichia coli K12 ML1629.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212007"} {"pmid": "4212008", "title": "EM autoradiographic studies on polytene nuclei of Drosophila melanogaster. 3. Localisation of non-replicating chromatin in the chromocentre heterochromatin.", "content": "EM autoradiographic studies on polytene nuclei of Drosophila melanogaster. 3. Localisation of non-replicating chromatin in the chromocentre heterochromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212008"} {"pmid": "4212009", "title": "Factors affecting the uptake of glibenclamide in microdissected pancreatic islets rich in beta-cells.", "content": "Factors affecting the uptake of glibenclamide in microdissected pancreatic islets rich in beta-cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212009"} {"pmid": "4212010", "title": "Failure of thyrotropin releasing hormone to increase 125-I uptake by the thyroid in rana temporaria.", "content": "Failure of thyrotropin releasing hormone to increase 125-I uptake by the thyroid in rana temporaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212010"} {"pmid": "4212011", "title": "Fenfluramine: amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey.", "content": "Fenfluramine: amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey. Fenfluramine, over a dose range from 0.003 to 3 milligrams per kilogram of body weight, failed to maintain self-injection behavior in rhesus monkeys that had initiated and maintained responding for cocaine or methohexital. This absence of a positive reinforcing effect could not be attributed to a slow onset of drug effect or to the use of behaviorally inactive doses. Fenfluramine, because of its distinctive properties, may produce fewer problems of human abuse than do amphetamine-type agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212011"} {"pmid": "4212005", "title": "Extensive binding of concanavalin A to the nuclear membrane.", "content": "Extensive binding of concanavalin A to the nuclear membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212005"} {"pmid": "4212012", "title": "Fibrin degradation products in the serum and cerebrospinal fluid of patients with group A meningococcal meningitis.", "content": "Fibrin degradation products in the serum and cerebrospinal fluid of patients with group A meningococcal meningitis. Forty-one patients suffering from group A meningococcal meningitis in an area within the epidemic meningococcal belt of tropical West Africa were studied. The serum of only two of these patients contained fibrin degradation products (FDPs). The cerebrospinal fluid of 21 of these cases was also examined for FDPs, which were present in 13. Their presence in the cerebrospinal fluid was associated with a poor prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212012"} {"pmid": "4212013", "title": "Fibrinogen-fibrin degradation products and factor XIII.", "content": "Fibrinogen-fibrin degradation products and factor XIII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212013"} {"pmid": "4212014", "title": "Fibrinolysis and factor XIII.", "content": "Fibrinolysis and factor XIII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212014"} {"pmid": "4212015", "title": "Fibrous tumor of infancy--report of a case originating in the oral cavity.", "content": "Fibrous tumor of infancy--report of a case originating in the oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212015"} {"pmid": "4212016", "title": "Fine structure of the sporozoite of Schellackia occidentalis.", "content": "Fine structure of the sporozoite of Schellackia occidentalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212016"} {"pmid": "4211996", "title": "Experience with temporary tube gastrostomy for postoperative gastric decompression.", "content": "Experience with temporary tube gastrostomy for postoperative gastric decompression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4211996"} {"pmid": "4212017", "title": "First clinical experience on the antiepileptic action of taurine.", "content": "First clinical experience on the antiepileptic action of taurine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212017"} {"pmid": "4212018", "title": "Focal dermal hypoplasia.", "content": "Focal dermal hypoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212018"} {"pmid": "4212019", "title": "Folic acid and dilantin antagonism in pregnancy.", "content": "Folic acid and dilantin antagonism in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212019"} {"pmid": "4212020", "title": "Fracture conference: Arthrograms of the ankle. Their role in acute trauma.", "content": "Fracture conference: Arthrograms of the ankle. Their role in acute trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212020"} {"pmid": "4212022", "title": "Further studies on the effect of ambilhar on iron metabolism.", "content": "Further studies on the effect of ambilhar on iron metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212022"} {"pmid": "4212021", "title": "Further characterization of the antigens of canine prostatic fluid.", "content": "Further characterization of the antigens of canine prostatic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212021"} {"pmid": "4212023", "title": "Further studies on the isotope modification of the mixed hemadsorption technique. Factors influencing the prozone effect.", "content": "Further studies on the isotope modification of the mixed hemadsorption technique. Factors influencing the prozone effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212023"} {"pmid": "4212024", "title": "Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis).", "content": "Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212024"} {"pmid": "4212025", "title": "Galapagos iguanas: Amblyrhynchus and Conolophus serum protein relationships.", "content": "Galapagos iguanas: Amblyrhynchus and Conolophus serum protein relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212025"} {"pmid": "4212027", "title": "Gastric acid and plasma gastrin responses to sham feeding in duodenal ulcer patients before and after resection of antrum and duodenal bulb.", "content": "Gastric acid and plasma gastrin responses to sham feeding in duodenal ulcer patients before and after resection of antrum and duodenal bulb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212027"} {"pmid": "4212026", "title": "Gas chromatographic assay of iduronic and glucuronic acids as aldonic acid butaneboronates.", "content": "Gas chromatographic assay of iduronic and glucuronic acids as aldonic acid butaneboronates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212026"} {"pmid": "4212028", "title": "Gastric acid does drive pancreatic bicarbonate secretion.", "content": "Gastric acid does drive pancreatic bicarbonate secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212028"} {"pmid": "4212029", "title": "Genetic and biochemical studies on cell-bound alpha-amylase in Bacillus subtilis Marburg.", "content": "Genetic and biochemical studies on cell-bound alpha-amylase in Bacillus subtilis Marburg. A small but significant amount of alpha-amylase activity was detected in the cells of Bacillus subtilis Marburg. The cell-associated activity was almost constant regardless of the level of extracellular alpha-amylase activity. The cell-bound amylase activity could be separated into three components, upon Sephadex G-75 chromatography, referred to as components A, B, and C. Component C showed the same properties as the extracellular alpha-amylases so far examined. Component A had a molecular weight greater than 70,000, as judged from the elution position on Sephadex G-75, and became smaller upon treatment with trypsin but was still larger than that of component C. An alpha-amylase mutant that lacked extracellular alpha-amylase completely because of a mutation within the structural gene of the enzyme was found to lose all three cell-bound amylase components simultaneously. These data suggest strongly that the cell-bound amylase components are precursors of the extracellular alpha-amylase and that the alpha-amylase of this organism is produced under the direction of the same gene whether the enzyme is within or outside the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212029"} {"pmid": "4212030", "title": "Genetic control of the rate of alpha-amylase synthesis in Bacillus subtilis.", "content": "Genetic control of the rate of alpha-amylase synthesis in Bacillus subtilis. The level of extracellular alpha-amylase (EC 3.2.1.1) of Bacillus subtilis Marburg was increased about fivefold by introducing the amyR marker from B. natto 1212 through transformation. amyR2 of B. natto 1212 has been assumed to determine a high level of alpha-amylase of the organism. The gene acts specifically on alpha-amylase synthesis but not on the production of other extracellular enzymes. alpha-Amylase of an amyR2-carrying strain was found to be quite similar to that of an isogenic amyR1-carrying strain in the thermostability and electrophoretic behavior of whichever amylase the strain produces. Marburg-type alpha-amylase (amyEm) or B. natto-alpha-amylase (amyEn). Anti-amylase serum titration indicates that a high level of the enzyme activity in the amyR2-carrying strain is caused by the existence of more enzyme rather than the presence of an enzyme having higher efficiency. This is supported further by the fact that amyR controls the synthesis of the amyE gene product in mutant M9, which synthesizes a temperature-sensitive-alpha-amylase, and in mutant M07, which secretes cross-reacting material. The results indicate that amyR regulates the rate of alpha-amylase synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212030"} {"pmid": "4212031", "title": "Genetic mapping in Bacillus subtilis by 5-bromouracil sensitization to ultraviolet inactivation of transforming activities.", "content": "Genetic mapping in Bacillus subtilis by 5-bromouracil sensitization to ultraviolet inactivation of transforming activities. A new method for chromosome mapping of Bacillus subtilis Marburg is presented which is based on the sensitization to ultraviolet irradiation of transforming deoxyribonucleic acid that has incorporated 5-bromouracil instead of thymine. Deoxyribonucleic acid was extracted at intervals from the outgrowing spores of a thymine-requiring mutant incubated with 5-bromodeoxyuridine and subjected to a definite dose of ultraviolet irradiation. The residual activities of various genetic markers were assayed by transformation. The marker activity of deoxyribonucleic acid that had incorporated 5-bromodeoxyuridine was approximately 10 times as sensitive to ultraviolet irradiation as that of normal deoxyribonucleic acid. The markers proximal to the replication origin were sensitized at earlier times of outgrowth than distal markers. The chromosome replication in outgrowing spores was sufficiently synchronous and allowed the definite determination of when a marker became sensitized by incorporation of 5-bromodeoxyuridine. The time, designated \"sensitization time,\" was estimated by plotting the logarithmic values of relative residual activities versus incubation times. The map constructed with sensitization times as a measurement showed good agreement with those constructed by other methods. The replication of the chromosome under the described conditions appeared to occur in the following marker order: (purA, hisA)-(purB)-(thr, pyrA)-(metC)-(leuA)-(lys, trpC, metB).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212031"} {"pmid": "4212032", "title": "Genetical load in man.", "content": "Genetical load in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212032"} {"pmid": "4212035", "title": "Gluconeogenesis in ruminants: glucose kinetic parameters in calves under standardized conditions.", "content": "Gluconeogenesis in ruminants: glucose kinetic parameters in calves under standardized conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212035"} {"pmid": "4212034", "title": "Glucokinase and glucose 6-phosphate dehydrogenase in Neisseria.", "content": "Glucokinase and glucose 6-phosphate dehydrogenase in Neisseria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212034"} {"pmid": "4212033", "title": "Genitourinary tuberculosis: review of 102 cases.", "content": "Genitourinary tuberculosis: review of 102 cases. Clinical presentations, laboratory features, and responses to therapy of 102 patients treated at an army medical center for genitourinary tuberculosis between January 1961 and September 1972 are described. During that time, a total of 3109 patients had been treated for tuberculosis of all types. The study group included 72 men aged 18-59 with a mean age of 29, and 31 women aged 17-66, with a mean age of 31. There was often a latent period of 20 years or more between infection with the tubercle bacillus and the expression of genitourinary tuberculosis. The principal means of diagnosis was isolation of Mycobacterium tuberculosis from urine, obtained in 80%, or sputum, obtained in 38%. M. tuberculosis was not cultured in 13 patients. In patients with negative cultures, diagnosis was made by combinations of positive tuberculin skin test, caseating granulomata on biopsy, characteristic changes in the excretory urogram, characteristic bladder lesions on cystoscopy, and the presence of sterile pyuria or microscopic hematuria. A wide variety of signs and symptoms were encountered as was a high frequency of involvement of other organ systems. The most common laboratory abnormalities were pyuria, albuminuria, and hematuria. 75% of patients had an abnormal chest roentgenogram on admission. 88% of patients tested had positive skin tests and 63% tested had abnormal excretory urography. 16% showed renal calcification. Only 1 nephrectomy was done in the latter 5 years of the study, for hypertension. 2 women and 6 men had hypertension, but 1 woman and 2 men had nontuberculous renal disease which could have caused the hypertension. The evidence from the series is that infectivity of genitourinary tuberculosis is low. There was only 1 initial treatment failure, in a 47-year old man with active pulmonary and renal tuberculosis caused by an isoniazid-resistant organism. 2 men, only 1 of whom had had genitourinary disease originally, had recurrences of tuberculous disease after prematurely discontinuing medication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212033"} {"pmid": "4212036", "title": "Glycogen metabolism in glycogen-rich erythrocytes.", "content": "Glycogen metabolism in glycogen-rich erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212036"} {"pmid": "4212037", "title": "Glycosyl transferase activity in normal and Scrapie-affected mouse brain.", "content": "Glycosyl transferase activity in normal and Scrapie-affected mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212037"} {"pmid": "4212038", "title": "Gonococcal oro- and nasopharyngeal infection.", "content": "Gonococcal oro- and nasopharyngeal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212038"} {"pmid": "4212040", "title": "Granulocyte transfusion therapy of experimental Pseudomonas pneumonia.", "content": "Granulocyte transfusion therapy of experimental Pseudomonas pneumonia. Pseudomonas pneumonia was produced in dogs with radiation-induced leukopenia. Treatment of this infection with either gentamicin alone or gentamicin plus daily granulocyte transfusion was compared in a randomized controlled trail. The dogs receiving granulocytes plus gentamicin survived significantly longer than those treated with gentamicin alone (P < 0.05). The Pseudomonas immunotype which was inoculated into the dogs were recovered at autopsy from none of the granulocyte-transfused dogs, whereas seven or eight of the dogs treated with gentamicin alone had the inoculated Pseudomonas immunotype in the area of induced pneumonia at autopsy. As measured by the limulus test, the granulocyte-transfused dogs also did not have endotoxemia as frequently as the dogs given only gentamicin (P < 0.05). This controlled study establishes that transfused granulocytes can favorably alter the course of experimental Pseudomonas pneumonia and suggests that granulocyte transfusion may be a useful therapy in serious bacterial infections of leukopenic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212040"} {"pmid": "4212041", "title": "Granulomatous reaction in experimental stapedectomy.", "content": "Granulomatous reaction in experimental stapedectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212041"} {"pmid": "4212042", "title": "Growth of the Bacillus subtilis cell surface.", "content": "Growth of the Bacillus subtilis cell surface. A double mutant strain, Bacillus subtilis div IV B1 dal trp, has been constructed which grows as filamentous cells and minicells and requires d-alanine for growth. Removal of d-alanine from a growing population of cells resulted in cell bulging 25% of the cell length from one cell pole, followed by cell lysis. Little ultrastructural change in the cell envelope could be detected during bulge formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212042"} {"pmid": "4212043", "title": "GLC determination of fluorouracil.", "content": "GLC determination of fluorouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212043"} {"pmid": "4212044", "title": "GP-350, a sialoglycoprotein from calf brain: its subcellular localization and occurrence in various brain areas.", "content": "GP-350, a sialoglycoprotein from calf brain: its subcellular localization and occurrence in various brain areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212044"} {"pmid": "4212045", "title": "Haemoglobin inkster (alpha2 85aspartic acid leads to valine beta2) coexisting with beta-thalassaemia in a Caucasian family.", "content": "Haemoglobin inkster (alpha2 85aspartic acid leads to valine beta2) coexisting with beta-thalassaemia in a Caucasian family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212045"} {"pmid": "4212046", "title": "Haemoglobin Madrid beta 115 (G17) alanine--proline: an unstable variant associated with haemolytic anaemia.", "content": "Haemoglobin Madrid beta 115 (G17) alanine--proline: an unstable variant associated with haemolytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212046"} {"pmid": "4212047", "title": "Haemolytic disease of new-born due to anti-D antibodies in a Du-positive mother.", "content": "Haemolytic disease of new-born due to anti-D antibodies in a Du-positive mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212047"} {"pmid": "4212039", "title": "Gonococcal pharyngitis. A report of four cases and a review of the literature.", "content": "Gonococcal pharyngitis. A report of four cases and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212039"} {"pmid": "4212049", "title": "Hematologic malignancies and other marrow failure states: progress in the management of complicating infections.", "content": "Hematologic malignancies and other marrow failure states: progress in the management of complicating infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212049"} {"pmid": "4212048", "title": "Haemostatic defects in myelofibrosis.", "content": "Haemostatic defects in myelofibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212048"} {"pmid": "4212050", "title": "Heterogeneity of monoclonal immunoglobulin-G proteins studied by isoelectric focusing.", "content": "Heterogeneity of monoclonal immunoglobulin-G proteins studied by isoelectric focusing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212050"} {"pmid": "4212052", "title": "Heterotrophic growth of the nitrogen fixing blue-green alga Nostoc muscorum.", "content": "Heterotrophic growth of the nitrogen fixing blue-green alga Nostoc muscorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212052"} {"pmid": "4212053", "title": "Histamine content of hypothalamic nuclei of the rat.", "content": "Histamine content of hypothalamic nuclei of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212053"} {"pmid": "4212054", "title": "Histochemical evidence of a hormonal stimulation affecting the postnatal development of murine Paneth cells.", "content": "Histochemical evidence of a hormonal stimulation affecting the postnatal development of murine Paneth cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212054"} {"pmid": "4212055", "title": "Homocystinemia. Vascular injury and arterial thrombosis.", "content": "Homocystinemia. Vascular injury and arterial thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212055"} {"pmid": "4212056", "title": "Homologies in procaryotic ribosomal proteins: alanine rich acidic proteins associated with polypeptide translocation.", "content": "Homologies in procaryotic ribosomal proteins: alanine rich acidic proteins associated with polypeptide translocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212056"} {"pmid": "4212057", "title": "Homology of amino-terminal regions of C-phycocyanins from a prokaryote and a eukaryote.", "content": "Homology of amino-terminal regions of C-phycocyanins from a prokaryote and a eukaryote.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212057"} {"pmid": "4212051", "title": "Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen.", "content": "Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212051"} {"pmid": "4212059", "title": "Hydrophobic grid-membrane filters: new approach to microbiological enumeration.", "content": "Hydrophobic grid-membrane filters: new approach to microbiological enumeration. A square grid pattern, printed in hydrophobic material on conventional membrane filters, subdivided the surface into a plurality of areas. This separated colonies from one another and prevented lateral growth, spreading, and confluence. Very high colony-packing densities were achieved (2,500/in(2); ca. 1.61 x 10(5)/cm(2)) reducing the need to dilute samples. Recovery of organisms was better than on conventional filters, particularly at high inoculum levels. At the same time, visibility of normally pale or diffuse colonies was improved, since colonies grew upwards instead of sideways, and counting was facilitated because colonies grew in orderly arrays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212059"} {"pmid": "4212058", "title": "Hybridization studies with RNA and DNA isolated from Euglena gracilis chloroplasts and mitochondria.", "content": "Hybridization studies with RNA and DNA isolated from Euglena gracilis chloroplasts and mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212058"} {"pmid": "4212062", "title": "Identification of cone mechanisms in graded responses of foveal striate cortex.", "content": "Identification of cone mechanisms in graded responses of foveal striate cortex. 1. The earliest electrical response detectable in foveal striate cortex of anaesthetized Rhesus monkeys following light stimulation is a graded potential which is positive at the cortical surface and negative in the grey matter and has a peak latency of about 60 msec. The response is similar at both the on- and the off-phase of a light stimulus.2. The relationship of this graded potential to the depth of the recording electrode, to the latency of extracellular impulses and to post-synaptic potentials suggests that it is generated by the depolarization of cortical cells.3. Action spectra obtained in the presence of strong selective chromatic adaptation indicate the participation of all three cone mechanisms in this response.4. Each cone mechanism contributes a similar potential to the response but antagonism between cone mechanisms is apparent. The proportion in which a cone mechanism contributes to the response varies from one area to another implying topographical differences in the representation of cone mechanisms in striate cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212062"} {"pmid": "4212061", "title": "Hypothalamic catecholamines and adrenergic innervation of hypothalamic blood vessels. Potential role in shock.", "content": "Hypothalamic catecholamines and adrenergic innervation of hypothalamic blood vessels. Potential role in shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212061"} {"pmid": "4212064", "title": "Identification of primate hair.", "content": "Identification of primate hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212064"} {"pmid": "4212063", "title": "Identification of group B streptococci by immunofluorescence staining.", "content": "Identification of group B streptococci by immunofluorescence staining. Gamma globulin fractions of rabbit antisera prepared with whole cell vaccines of group B types Ia, Ib, II, and III and labeled with fluorescein isothiocyanate stained group B streptococci type specifically. Type Ic cells, which contain the Ia polysaccharide antigen of type Ia and the Ic protein antigen of type Ib, were specifically stained by both Ia and Ib conjugates. A group B conjugate pool (B pool) that contained one conjugate specific for each group B type at its predetermined titer gave positive fluorescent-antibody (FA) reactions (4+ intensity) with group B stock strains and negative FA reactions (less than 2+ intensity) with stock strains of streptococcal groups A, C through H, and K through U, viridans streptococci, Streptococcus pneumoniae, Staphylococcus aureus, Neisseria gonorrhoeae, and representative Enterobacteriaceae. Examination of 883 clinical isolates submitted to the Streptococcus Laboratory (Center for Disease Control, Atlanta, Ga.) for identification revealed a 99.1% agreement between FA and culture-precipitin methods. All 305 group B streptococci identified by culture-precipitin and six nonhemolytic group B streptococci missed initially by culture tests were identified correctly by FA. Results of cultural and FA methods in a double-blind study of 99 vaginal swabs agreed on 96 of 99 strains. Three nonhemolytic group B streptococci were identified first by FA and later confirmed by culture-precipitin tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212063"} {"pmid": "4212065", "title": "IgG hydrolysis in abscesses. I. A study of the IgG in human abscess fluid.", "content": "IgG hydrolysis in abscesses. I. A study of the IgG in human abscess fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212065"} {"pmid": "4212066", "title": "Immune reactions of the syngeneic host after the intradermal injection of tumor cells and microsomes.", "content": "Immune reactions of the syngeneic host after the intradermal injection of tumor cells and microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212066"} {"pmid": "4212067", "title": "Immunity and malaria in man.", "content": "Immunity and malaria in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212067"} {"pmid": "4212069", "title": "Immunodiffusion studies on sera from animals infected with Schistosoma japonicum.", "content": "Immunodiffusion studies on sera from animals infected with Schistosoma japonicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212069"} {"pmid": "4212068", "title": "Immunoassay using antibody--enzyme conjugates.", "content": "Immunoassay using antibody--enzyme conjugates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212068"} {"pmid": "4212070", "title": "Immunofluorescence test for persistent poxvirus antibodies.", "content": "Immunofluorescence test for persistent poxvirus antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212070"} {"pmid": "4212071", "title": "Immunoglobulin D (IgD) in childhood. II. Serum IgD levels in juvenile rheumatoid arthritis.", "content": "Immunoglobulin D (IgD) in childhood. II. Serum IgD levels in juvenile rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212071"} {"pmid": "4212060", "title": "Hyperalimentation as preparation for surgery in transmural colitis (Crohn's disease).", "content": "Hyperalimentation as preparation for surgery in transmural colitis (Crohn's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212060"} {"pmid": "4212072", "title": "Immunoglobulins G and M in newborn cord serum.", "content": "Immunoglobulins G and M in newborn cord serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212072"} {"pmid": "4212074", "title": "Impaired platelet function in glucose-6-phosphatase deficiency.", "content": "Impaired platelet function in glucose-6-phosphatase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212074"} {"pmid": "4212073", "title": "Immunological studies of brain specific protein.", "content": "Immunological studies of brain specific protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212073"} {"pmid": "4212075", "title": "Improved method of nasojejunal feeding in low-birth-weight infants.", "content": "Improved method of nasojejunal feeding in low-birth-weight infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212075"} {"pmid": "4212076", "title": "In vitro hydrolysis of prostaglandin F2alpha, esters by serum or plasma of different animal species.", "content": "In vitro hydrolysis of prostaglandin F2alpha, esters by serum or plasma of different animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212076"} {"pmid": "4212078", "title": "In vitro restoration of deficient beta-galactosidase activity in liver of patients with Hurler and Hunter disease.", "content": "In vitro restoration of deficient beta-galactosidase activity in liver of patients with Hurler and Hunter disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212078"} {"pmid": "4212077", "title": "In vitro metabolism of testosterone in seminal vesicles of rats.", "content": "In vitro metabolism of testosterone in seminal vesicles of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212077"} {"pmid": "4212079", "title": "In vivo studies on the uptake and binding of beta-lactam antibiotics in relation to inhibition of wall synthesis and cell death.", "content": "In vivo studies on the uptake and binding of beta-lactam antibiotics in relation to inhibition of wall synthesis and cell death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212079"} {"pmid": "4212080", "title": "Incidence of antiprotozoal and antivermal antibiotics in fungi. IV. Fungi imperfecti, order Moniliales, collected in China.", "content": "Incidence of antiprotozoal and antivermal antibiotics in fungi. IV. Fungi imperfecti, order Moniliales, collected in China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212080"} {"pmid": "4212081", "title": "Increase of fungitoxicity of mercuric chloride by methionine, ethionine and S-methylcysteine.", "content": "Increase of fungitoxicity of mercuric chloride by methionine, ethionine and S-methylcysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212081"} {"pmid": "4212082", "title": "Increased diamine oxidase activity in the intestinal lymph of rats on fat ingestion.", "content": "Increased diamine oxidase activity in the intestinal lymph of rats on fat ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212082"} {"pmid": "4212083", "title": "Increased elevation of peripheral leukocyte counts by infusion of histocompatible granulocytes.", "content": "Increased elevation of peripheral leukocyte counts by infusion of histocompatible granulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212083"} {"pmid": "4212085", "title": "Induction of chronic growth hormone deficiency by anti-GH serum.", "content": "Induction of chronic growth hormone deficiency by anti-GH serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212085"} {"pmid": "4212084", "title": "Independence of iron absorption from the rate of erythropoiesis.", "content": "Independence of iron absorption from the rate of erythropoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212084"} {"pmid": "4212086", "title": "Infantile obesity and later weight control in the baboon.", "content": "Infantile obesity and later weight control in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212086"} {"pmid": "4212087", "title": "Influence of acids and salts on the efficiency of the dialyser in the automated analysis of sialic acid.", "content": "Influence of acids and salts on the efficiency of the dialyser in the automated analysis of sialic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212087"} {"pmid": "4212088", "title": "Influence of dietary factors on the gastrointestinal absorption of lead.", "content": "Influence of dietary factors on the gastrointestinal absorption of lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212088"} {"pmid": "4212090", "title": "Inhibition of intestinal absorption of folic acid by phenytoin.", "content": "Inhibition of intestinal absorption of folic acid by phenytoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212090"} {"pmid": "4212091", "title": "Inhibition of the oxytocic action of prostaglandin F2alpha on pregnant rabbit uterus by intra-aortic infusion of theophylline in vivo.", "content": "Inhibition of the oxytocic action of prostaglandin F2alpha on pregnant rabbit uterus by intra-aortic infusion of theophylline in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212091"} {"pmid": "4212089", "title": "Inhibition of antibody formation during continual stimulation with a strong immunogen.", "content": "Inhibition of antibody formation during continual stimulation with a strong immunogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212089"} {"pmid": "4212092", "title": "Inhibition of Streptomyces griseus protease B by peptide chloromethyl ketones: partial mapping of the binding site and identification of the reactive residue.", "content": "Inhibition of Streptomyces griseus protease B by peptide chloromethyl ketones: partial mapping of the binding site and identification of the reactive residue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212092"} {"pmid": "4212094", "title": "Inputs into coronary care during 30 years. A cost effectiveness study.", "content": "Inputs into coronary care during 30 years. A cost effectiveness study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212094"} {"pmid": "4212093", "title": "Initiation of spore germination in Bacillus subtilis: relationship to inhibition of L-alanine metabolism.", "content": "Initiation of spore germination in Bacillus subtilis: relationship to inhibition of L-alanine metabolism. The inhibitory effects of anthranilic acid esters (methyl anthranilate and N-methyl anthranilate) on the l-alanine-induced initiation of spore germination was examined in Bacillus subtilis 168. Methyl anthranilate irreversibly inhibited alanine initiation by a competitive mechanism. In its presence, the inhibition could be reversed only by the combined addition of d-glucose, d-fructose, and K(+). Both l-alanine dehydrogenase and l-glutamate-pyruvate transaminase, enzymes which catalyze the first reaction in l-alanine metabolism, were competitively inhibited by methyl anthranilate. The K(i) values for germination initiation (0.053 mM) and of l-glutamate-pyruvate transaminase (0.068 mM) were similar, whereas that for l-alanine dehydrogenase (0.4 mM) was six to seven times higher. Since a mutant lacking l-alanine dehydrogenase activity germinated normally in l-alanine alone, it is speculated that the major pathway of l-alanine metabolism during initiation may be via transmination reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212093"} {"pmid": "4212096", "title": "Instrumental detection system based on light scattering for performing assays in which agglutination reactions are used.", "content": "Instrumental detection system based on light scattering for performing assays in which agglutination reactions are used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212096"} {"pmid": "4212095", "title": "Insensitivity of homocitrate synthase in extracts of Penicillium chyrosogenum to feedback inhibition by lysine.", "content": "Insensitivity of homocitrate synthase in extracts of Penicillium chyrosogenum to feedback inhibition by lysine. We previously reported that lysine inhibits in vivo homocitrate synthesis in the lysine bradytroph, Penicillium chrysogenum L(1), and that such feedback inhibition could explain the known lysine inhibition of penicillin formation. In the present study, it was found that dialyzed cell-free extracts of mutant L(1) converted [1-(14)C]acetate to homocitrate. This homocitrate synthase activity was extremely labile but could be stabilized by high salt concentrations. The pH optimum of the reaction was 6.9, and the K(m) was 5.5 mM with respect to alpha-ketoglutarate. The reaction was also dependent upon the presence of Mg(2+), adenosine 5'-triphosphate, and coenzyme A. Surprisingly, the activity in these crude extracts was not inhibited by lysine. Benzylpenicillin at a high concentration (20 mM) partially inhibited the enzyme, an effect that was enhanced by lysine. Casein hydrolysate also partially inhibited the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212095"} {"pmid": "4212097", "title": "Insulin is a Drosophila hormone and acts to enhance the differentiation of embryonic Drosophila cells.", "content": "Insulin is a Drosophila hormone and acts to enhance the differentiation of embryonic Drosophila cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212097"} {"pmid": "4212098", "title": "Insulin-resistant diabetic coma. Acute onset in an unknown diabetic associated with brain-stem infarction and death.", "content": "Insulin-resistant diabetic coma. Acute onset in an unknown diabetic associated with brain-stem infarction and death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212098"} {"pmid": "4212099", "title": "Interaction of 125I-thyroxine with rat adenohypophyseal proteins in vitro: effect of temperature.", "content": "Interaction of 125I-thyroxine with rat adenohypophyseal proteins in vitro: effect of temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212099"} {"pmid": "4212100", "title": "Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from Bacillus subtilis 168.", "content": "Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from Bacillus subtilis 168. Membrane vesicles isolated from competent cultures of Bacillus subtilis 168 bound up to 20 mug of double-stranded deoxyribonucleic acid (DNA) per mg of membrane protein in the presence of ethylenediaminetetraacetate. The formation of the DNA-membrane complex was time, temperature, and pH dependent. Eighty per cent of the DNA could be removed from the complex by treatment with deoxyribonuclease I. Nevertheless, the DNA that remained attached to the vesicles appeared to have been attacked by the enzyme, suggesting that all the complexed DNA is located at the outer surface of the vesicles. Pretreatment of DNA with deoxyribonuclease I destroyed its affinity for the vesicles. The extent of binding decreased by the addition of Mg(2+) ions, especially at high DNA concentrations (more than 2 mug/ml). This effect was partially due to membrane-associated Mg(2+)-dependent endonucleolytic activity, which caused double-strand breaks in addition to single-strand nicks, and to exonuclease activity. The endonucleolytic activity was enhanced by heating the membranes at 80 C. DNA-membrane association was not markedly affected by sulfhydryl reagents, but was largely inhibited by formaldehyde. Endogenous competence-stimulating activity did not alter the DNA-binding capacity of the vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212100"} {"pmid": "4212101", "title": "Interactions of narcotic antagonists with receptor sites.", "content": "Interactions of narcotic antagonists with receptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212101"} {"pmid": "4212102", "title": "Interrelationships of the fibrinolytic, coagulation, kinin generating and complement systems.", "content": "Interrelationships of the fibrinolytic, coagulation, kinin generating and complement systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212102"} {"pmid": "4212103", "title": "Intestinal complications of nasojejunal feeding in low-birth-weight infants.", "content": "Intestinal complications of nasojejunal feeding in low-birth-weight infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212103"} {"pmid": "4212105", "title": "Intestinal effects of 5-hydroxytryptamine and morphine in guinea pigs, dogs, cats and monkeys.", "content": "Intestinal effects of 5-hydroxytryptamine and morphine in guinea pigs, dogs, cats and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212105"} {"pmid": "4212104", "title": "Intestinal disaccharidases in primary protein malnutrition in adults.", "content": "Intestinal disaccharidases in primary protein malnutrition in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212104"} {"pmid": "4212106", "title": "Intracellular localization of pyridoxamine-5-phosphate oxidase in rabbit liver.", "content": "Intracellular localization of pyridoxamine-5-phosphate oxidase in rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212106"} {"pmid": "4212107", "title": "Intragastric self-administration of morphine as a measure of addiction.", "content": "Intragastric self-administration of morphine as a measure of addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212107"} {"pmid": "4212108", "title": "Investigation of the alpha-galactosidase deficiency in Fabry's disease using antibodies against the purified enzyme.", "content": "Investigation of the alpha-galactosidase deficiency in Fabry's disease using antibodies against the purified enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212108"} {"pmid": "4212109", "title": "Involvement of mannosyl-phosphoryl-dolichols in mannose transfer to brain glycoproteins.", "content": "Involvement of mannosyl-phosphoryl-dolichols in mannose transfer to brain glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212109"} {"pmid": "4212110", "title": "Is singlet oxygen a substrate for superoxide dismutase? No.", "content": "Is singlet oxygen a substrate for superoxide dismutase? No.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212110"} {"pmid": "4212111", "title": "Is there a venoarterial difference in alpha 1-antitrypsin levels?", "content": "Is there a venoarterial difference in alpha 1-antitrypsin levels? Serum trypsin inhibitory capacity and alpha(1)-antitrypsin concentrations were compared in venous and arterial bloods obtained simultaneously from patients with chronic airways obstruction. No significant venoarterial difference was observed in most patients, which was contrary to the published findings of Woolcock et al. (1972).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212111"} {"pmid": "4212112", "title": "Isolation and properties of a staphylococcal protease, preferentially cleaving glutamoyl-peptide bonds.", "content": "Isolation and properties of a staphylococcal protease, preferentially cleaving glutamoyl-peptide bonds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212112"} {"pmid": "4212113", "title": "Isolation of a common cell wall antigen from the proteolytic strains of Clostridium botulinum.", "content": "Isolation of a common cell wall antigen from the proteolytic strains of Clostridium botulinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212113"} {"pmid": "4212114", "title": "Isolation of a complex of the subcomponents of the activated first component of complement, Clr--Cls, from ACD-human plasma.", "content": "Isolation of a complex of the subcomponents of the activated first component of complement, Clr--Cls, from ACD-human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212114"} {"pmid": "4212115", "title": "Isolation of a fragment, Fh, corresponding to the hinge region of human IgG3.", "content": "Isolation of a fragment, Fh, corresponding to the hinge region of human IgG3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212115"} {"pmid": "4212116", "title": "Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses.", "content": "Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses. The rate of alpha-amylase (EC 3.2.1.1) synthesis in Bacillus subtilis is regulated by a gene, amyR, located near a structural gene, amyE, for the enzyme. To construct a fine map of the amyR-amyE region, we isolated 28 mutants defective in alpha-amylase activity. Eleven mutants out of 28 showed no alpha-amylase activity, whereas the other 17 showed less alpha-amylase activity than the parent. Out of 17 partially positive alpha-amylase mutants, 10 produced temperature-sensitive enzymes, and 4 produced immunologically altered enzymes, two of which are concurrently temperature-sensitive, and 5 produced smaller amounts of alpha-amylases which are indistinguishable from normal enzyme in their temperature sensitivity and immunological properties. Two out of 11 alpha-amylase-negative mutants produced material that cross-reacted with anti-amylase serum, and 3 mutants carried suppressible mutations by the suppressor described by Okubo. Mapping data indicate that all 28 mutation sites are located in the amyE region, and none of the groups of the mutants mentioned above contains lesions that are clustered in a single region of amyE. The amyR gene seems most likely to adjoin the terminal region of amyE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212116"} {"pmid": "4212117", "title": "Isotopic labeling and analysis of phosphoproteins from mammalian ribosomes.", "content": "Isotopic labeling and analysis of phosphoproteins from mammalian ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212117"} {"pmid": "4212119", "title": "Kinetics of complex formation between human carbonic anhydrase B and heterocyclic sulfonamides.", "content": "Kinetics of complex formation between human carbonic anhydrase B and heterocyclic sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212119"} {"pmid": "4212118", "title": "Kinetic cell-cycle analysis of a cultured mammalian cell population.", "content": "Kinetic cell-cycle analysis of a cultured mammalian cell population. The parameters of the cell cycle are analyzed in terms of the stochastic theory of cell proliferation for a murine mastocytoma line. The cells were grown in suspension culture under steady-state conditions in a chemostat. Initial estimates of the parameters from synchronous growth indicate that agreement of the data with the model is obtained only if the model is modified to include an initial proliferating fraction of less than 100%, and a cell loss continuing throughout the course of the experiment. The analysis verifies that the modified theory adequately describes the data, and that similar parameters are obtained from both desynchronization and percent labeled mitosis experiments. The average cycle time from 10 desynchronization experiments was 8.24 +/- 0.52 h with a cellular standard deviation of 1.28 +/- 0.18. The combined parameter obtained by dividing the cellular standard deviation by the cycle time is shown to be a useful measure of biological variability well defined over many different experiments. The rate constant for cell loss is about 0.009 which gives an 8% cell loss per cycle. The cell loss is sufficient to account for the apparent deficit in initially proliferating cells. The initial distribution of the synchronous cells is qualitatively examined and is found to be peaked late in G(1) or early in S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212118"} {"pmid": "4212121", "title": "Lactoperoxidase coupled to polyacrylamide for radio-iodination of proteins to high specific activity.", "content": "Lactoperoxidase coupled to polyacrylamide for radio-iodination of proteins to high specific activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212121"} {"pmid": "4212122", "title": "Lesions produced by Echis carinatus venom in experimental animals.", "content": "Lesions produced by Echis carinatus venom in experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212122"} {"pmid": "4212123", "title": "Letter from the Editor.", "content": "Letter from the Editor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212123"} {"pmid": "4212124", "title": "Letter: A cholinesterase inhibitor produced by Aspergillus terreus.", "content": "Letter: A cholinesterase inhibitor produced by Aspergillus terreus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212124"} {"pmid": "4212125", "title": "Letter: Bacterial microflora in infants receiving nasojejunal tube feeding.", "content": "Letter: Bacterial microflora in infants receiving nasojejunal tube feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212125"} {"pmid": "4212126", "title": "Letter: Colonial morphology of Neisseria gonorrhoeae.", "content": "Letter: Colonial morphology of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212126"} {"pmid": "4212128", "title": "Letter: Contaminated beta-lactamase and blood cultures.", "content": "Letter: Contaminated beta-lactamase and blood cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212128"} {"pmid": "4212120", "title": "Lack of effect of gold therapy on abnormal IgG and IgM metabolism in rheumatoid arthritis.", "content": "Lack of effect of gold therapy on abnormal IgG and IgM metabolism in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212120"} {"pmid": "4212127", "title": "Letter: Comments on papers by Reichert and Wong.", "content": "Letter: Comments on papers by Reichert and Wong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212127"} {"pmid": "4212129", "title": "Letter: Ear piercing.", "content": "Letter: Ear piercing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212129"} {"pmid": "4212130", "title": "Letter: Exercise-induced bronchospasm.", "content": "Letter: Exercise-induced bronchospasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212130"} {"pmid": "4212131", "title": "Letter: Glutaraldehyde therapy for epidermolysis bullosa.", "content": "Letter: Glutaraldehyde therapy for epidermolysis bullosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212131"} {"pmid": "4212132", "title": "Letter: Gonorrhea.", "content": "Letter: Gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212132"} {"pmid": "4212133", "title": "Letter: Immobilization of phosphotransferases obtained from resistant bacteria.", "content": "Letter: Immobilization of phosphotransferases obtained from resistant bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212133"} {"pmid": "4212134", "title": "Letter: Parenteral hyperalimentation.", "content": "Letter: Parenteral hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212134"} {"pmid": "4212135", "title": "Letter: Pheochromocytoma and tricyclic antidepressants.", "content": "Letter: Pheochromocytoma and tricyclic antidepressants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212135"} {"pmid": "4212136", "title": "Letter: Structure of enzymatically acetylated sisomicin by Pseudomonas aeruginosa.", "content": "Letter: Structure of enzymatically acetylated sisomicin by Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212136"} {"pmid": "4212137", "title": "Letter: The use of nabulized Intal in asthma.", "content": "Letter: The use of nabulized Intal in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212137"} {"pmid": "4212138", "title": "Letter: Thyroid thermogenesis.", "content": "Letter: Thyroid thermogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212138"} {"pmid": "4212140", "title": "Library service tailored to dental needs.", "content": "Library service tailored to dental needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212140"} {"pmid": "4212139", "title": "Leucocyte glycogen response in inflammatory exudates.", "content": "Leucocyte glycogen response in inflammatory exudates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212139"} {"pmid": "4212141", "title": "Life-threatening Mycoplasma pneumoniae pneumonia.", "content": "Life-threatening Mycoplasma pneumoniae pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212141"} {"pmid": "4212142", "title": "Lipids of potato tubers. IV. Effect of growth and storage on the lipid-degrading enzymes of the potato tuber.", "content": "Lipids of potato tubers. IV. Effect of growth and storage on the lipid-degrading enzymes of the potato tuber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212142"} {"pmid": "4212143", "title": "Liver iron: changes induced by cooking and acid-peptic digestion.", "content": "Liver iron: changes induced by cooking and acid-peptic digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212143"} {"pmid": "4212145", "title": "Localization of immunoglobulins in urinary bladder tumours.", "content": "Localization of immunoglobulins in urinary bladder tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212145"} {"pmid": "4212144", "title": "Localization of carbonic anhydrase in avian gastric mucosa, shell gland and bone by immunohistochemistry.", "content": "Localization of carbonic anhydrase in avian gastric mucosa, shell gland and bone by immunohistochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212144"} {"pmid": "4212146", "title": "Locomotor behavior of decerebellated arboreal mammals--monkey and raccoon.", "content": "Locomotor behavior of decerebellated arboreal mammals--monkey and raccoon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212146"} {"pmid": "4212147", "title": "Long-term care of the hemiplegic patient in the home.", "content": "Long-term care of the hemiplegic patient in the home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212147"} {"pmid": "4212148", "title": "Lupus erythematosus syndrome and complete deficiency of the fourth component of complement.", "content": "Lupus erythematosus syndrome and complete deficiency of the fourth component of complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212148"} {"pmid": "4212149", "title": "Lymphocyte function in breast cancer.", "content": "Lymphocyte function in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212149"} {"pmid": "4212150", "title": "Lysogenic conversion to phospholipase A production in Bacillus cereus.", "content": "Lysogenic conversion to phospholipase A production in Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212150"} {"pmid": "4212151", "title": "Lysozymes in feces from infants and children.", "content": "Lysozymes in feces from infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212151"} {"pmid": "4212152", "title": "Maintenance of the primary symbiote of the pea aphid Acyrthosiphon pisum in liquid media.", "content": "Maintenance of the primary symbiote of the pea aphid Acyrthosiphon pisum in liquid media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212152"} {"pmid": "4212153", "title": "Malnutrition and deafness.", "content": "Malnutrition and deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212153"} {"pmid": "4212154", "title": "Maternal and lateral transmission of scrapie in sheep.", "content": "Maternal and lateral transmission of scrapie in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212154"} {"pmid": "4212155", "title": "Measurement of intracellular amino acids in cultured skin fibroblasts. The effect of storage on cystine recovery and evaluation of three methods of cell preparation.", "content": "Measurement of intracellular amino acids in cultured skin fibroblasts. The effect of storage on cystine recovery and evaluation of three methods of cell preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212155"} {"pmid": "4212156", "title": "Mechanism of enzyme action.", "content": "Mechanism of enzyme action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212156"} {"pmid": "4212158", "title": "Membrane-bound transpeptidase and penicillin binding sites in Streptomyces strain R61.", "content": "Membrane-bound transpeptidase and penicillin binding sites in Streptomyces strain R61.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212158"} {"pmid": "4212157", "title": "Mechanisms underlying recovery of eye-head coordination following bilateral labyrinthectomy in monkeys.", "content": "Mechanisms underlying recovery of eye-head coordination following bilateral labyrinthectomy in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212157"} {"pmid": "4212159", "title": "Meningococcal vaccine.", "content": "Meningococcal vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212159"} {"pmid": "4212160", "title": "Messenger ribonucleic acid of dormant spores of Bacillus subtilis.", "content": "Messenger ribonucleic acid of dormant spores of Bacillus subtilis. Evidence of the presence of messenger ribonucleic acid (mRNA) in dormant spores of Bacillus subtilis has been obtained. The bulk RNA from spores was isolated and labeled in vitro with tritiated dimethyl sulfate. The spore RNA hybridized to 2.4 to 3.2% of the B. subtilis genome. The RNA hybridized to both the complementary heavy and light fractions of deoxyribonucleic acid (DNA). Bulk RNA from log-phase cells competed with virtually all the spore RNA for the heavy DNA fraction and with part of the spore RNA for the light DNA fraction. Bulk RNA from stage IV cells in sporulation also competed with all of the spore RNA for the heavy DNA fraction and with essentially all the spore RNA for the light DNA fraction. These results indicate that dormant spores contain mRNA species present in both log-phase cells and stage IV cells of sporulation. The RNA polymerase in the developing forespore must be able to recognize promotor sites for both log-phase and sporulation genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212160"} {"pmid": "4212161", "title": "Metabolism of ovomucoid by the developing chick embryo.", "content": "Metabolism of ovomucoid by the developing chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212161"} {"pmid": "4212162", "title": "Metabolism of trehalose in Euglena gracilis. Partial purification and some properties of phosphoglucomutase acting on beta-glucose 1-phosphate.", "content": "Metabolism of trehalose in Euglena gracilis. Partial purification and some properties of phosphoglucomutase acting on beta-glucose 1-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212162"} {"pmid": "4212163", "title": "Metaplastic ossification of a chronically inflamed anal sac in a dog (a case report).", "content": "Metaplastic ossification of a chronically inflamed anal sac in a dog (a case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212163"} {"pmid": "4212164", "title": "Methodology for the evaluation of pentazocine, prototype of the new morphine agonist-antagonist analgesics.", "content": "Methodology for the evaluation of pentazocine, prototype of the new morphine agonist-antagonist analgesics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212164"} {"pmid": "4212166", "title": "Microbial conversion of antibiotics. I. Deacylation of maridomycin by bacteria.", "content": "Microbial conversion of antibiotics. I. Deacylation of maridomycin by bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212166"} {"pmid": "4212165", "title": "Methods in the study of isoenzymes.", "content": "Methods in the study of isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212165"} {"pmid": "4212168", "title": "Microsporida of the fall webworn, Hyphantria cunea. I. Identification, distribution, and comparison of Nosema sp. with similar Nosema spp. from other Lepidoptera.", "content": "Microsporida of the fall webworn, Hyphantria cunea. I. Identification, distribution, and comparison of Nosema sp. with similar Nosema spp. from other Lepidoptera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212168"} {"pmid": "4212167", "title": "Microglioma with paraproteinaemia.", "content": "Microglioma with paraproteinaemia. A case is reported in which a solitary intracerebral tumour of lymphoreticular cells (microglioma, reticulum cell sarcoma) was associated with the presence of a serum paraprotein. Extensive investigation failed to show any evidence of extracerebral reticulosis. Response of the paraprotein to treatment of the tumour is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212167"} {"pmid": "4212170", "title": "Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora.", "content": "Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212170"} {"pmid": "4212169", "title": "Mild familial diabetes with dominant inheritance.", "content": "Mild familial diabetes with dominant inheritance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212169"} {"pmid": "4212171", "title": "Mitotic reduction in rat liver exposed to ultrasound.", "content": "Mitotic reduction in rat liver exposed to ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212171"} {"pmid": "4212172", "title": "Modification of hexachlorophene toxicity by dieldrin and aroclor 1254.", "content": "Modification of hexachlorophene toxicity by dieldrin and aroclor 1254.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212172"} {"pmid": "4212173", "title": "Modification of some of the toxic effects of daunomycin (NSC-82,151) by pretreatment with the antineoplastic agent ICRF 159 (NSC-129,943).", "content": "Modification of some of the toxic effects of daunomycin (NSC-82,151) by pretreatment with the antineoplastic agent ICRF 159 (NSC-129,943).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212173"} {"pmid": "4212174", "title": "Modification of the response of rats to lethal levels of ozone by enzyme-inducing agents.", "content": "Modification of the response of rats to lethal levels of ozone by enzyme-inducing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212174"} {"pmid": "4212175", "title": "Modulation of prolactin release by altered levels of thyroid hormones.", "content": "Modulation of prolactin release by altered levels of thyroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212175"} {"pmid": "4212176", "title": "Molecular studies on glycogen storage diseases.", "content": "Molecular studies on glycogen storage diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212176"} {"pmid": "4212178", "title": "Mothers and therapists evaluate long-term and short-term child therapy.", "content": "Mothers and therapists evaluate long-term and short-term child therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212178"} {"pmid": "4212177", "title": "Molecular weight heterogeneity of tropoelastin resulting from proteolysis during preparation.", "content": "Molecular weight heterogeneity of tropoelastin resulting from proteolysis during preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212177"} {"pmid": "4212179", "title": "Mucoepidermoid tumors of the intraoral minor salivary glands: a clinicopathologic study of 54 cases.", "content": "Mucoepidermoid tumors of the intraoral minor salivary glands: a clinicopathologic study of 54 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212179"} {"pmid": "4212180", "title": "Multiple exposure photography for B-scans.", "content": "Multiple exposure photography for B-scans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212180"} {"pmid": "4212181", "title": "Multiple myeloma and macroglobulinemia. Advances in treatment.", "content": "Multiple myeloma and macroglobulinemia. Advances in treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212181"} {"pmid": "4212182", "title": "Mutants of Bacillus subtilis bacteriophage phi e defective in dTTP-dUTP nucleotidohydrolase.", "content": "Mutants of Bacillus subtilis bacteriophage phi e defective in dTTP-dUTP nucleotidohydrolase. Mutants of bacteriophage phie inducing only 1 to 5% of wild-type levels of dTTP-dUTP nucleotidohydrolase give normal bursts of viable progeny phage whose DNA contains 5 to 10% thymine (but no uracil) in place of 5-hydroxymethyluracil. The relative heat lability of one phage mutant enzyme solubilized from the membrane fraction of infected cells suggests that a phie gene codes for the induced dTTPase-dUTPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212182"} {"pmid": "4212183", "title": "Mutational analysis of dark endogenous metabolism in the blue-green bacterium Anacystis nidulans.", "content": "Mutational analysis of dark endogenous metabolism in the blue-green bacterium Anacystis nidulans. We describe a mutant (strain 704) of the obligate photoautotroph Anacystis nidulans which behaves like the wild type under continuous illumination but which in the dark rapidly loses viability, respires little, and incorporates label into ribonucleic acid and protein at rates considerably less than observed with the darkened wild type. Extracts of this mutant strain show no detectable 6-phosphogluconate dehydrogenase (EC 1.1.1.44) activity. Spontaneous revertants of mutant 704 were selected as survivors of prolonged incubation in darkness. Of 10 such strains examined, none had regained 6-phosphogluconate dehydrogenase activity, and all had lost detectable glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity. Although dark survival of these revertants paralleled that of the wild type, rates of dark endogenous respiration and incorporation of labeled precursors into ribonucleic acid were still very low, comparable to those observed with strain 704. These results are consistent with the following hypotheses concerning dark endogenous metabolism in unicellular blue-green bacteria. (i) Although the oxidative pentose phosphate cycle (hexose monophosphate shunt) may play a major role in endogenous metabolism in A. nidulans, as proposed by others, it is not the only pathway capable of providing energy for maintenance of viability in darkness. (ii) Much of the endogenous metabolic activity (respiration and macromolecular synthesis) observed in darkened cultures of wild-type A. nidulans is not required for survival alone, and must therefore serve other functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212183"} {"pmid": "4212184", "title": "Mycobacterium kansasii in Kansas: saprophyte or infection?", "content": "Mycobacterium kansasii in Kansas: saprophyte or infection?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212184"} {"pmid": "4212186", "title": "N-terminal amino acid sequences of Azotobacter vinelandii and Rhodospirillum rubrum flavodoxins.", "content": "N-terminal amino acid sequences of Azotobacter vinelandii and Rhodospirillum rubrum flavodoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212186"} {"pmid": "4212188", "title": "Nasojejunal feeding: a commentary.", "content": "Nasojejunal feeding: a commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212188"} {"pmid": "4212187", "title": "Narcotic antagonists of the 4-phenylpiperidine series.", "content": "Narcotic antagonists of the 4-phenylpiperidine series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212187"} {"pmid": "4212189", "title": "National health insurance: can the U.S. learn from Canada?", "content": "National health insurance: can the U.S. learn from Canada?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212189"} {"pmid": "4212190", "title": "Nature of the serum heat-labile accessory factor involved in the metabolic inhibition of Mycoplasma pneumoniae.", "content": "Nature of the serum heat-labile accessory factor involved in the metabolic inhibition of Mycoplasma pneumoniae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212190"} {"pmid": "4212191", "title": "Necessity for differentiation of rhodochrous group from tubercle bacilli.", "content": "Necessity for differentiation of rhodochrous group from tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212191"} {"pmid": "4212192", "title": "Neuro-tuberculosis, An unsolved problem.", "content": "Neuro-tuberculosis, An unsolved problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212192"} {"pmid": "4212185", "title": "Myocardial and systemic vascular responses to low concentration of carboxyhemoglobin.", "content": "Myocardial and systemic vascular responses to low concentration of carboxyhemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212185"} {"pmid": "4212193", "title": "Neurofibroma with aberrant tactile corpuscles.", "content": "Neurofibroma with aberrant tactile corpuscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212193"} {"pmid": "4212194", "title": "Neuronal correlates of seasonal changes in contrast-detection of prey catching behaviour in toads (Bufo bufo L.).", "content": "Neuronal correlates of seasonal changes in contrast-detection of prey catching behaviour in toads (Bufo bufo L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212194"} {"pmid": "4212195", "title": "Neurotoxicologic studies of two carbamate pesticides in subacute animal experiments.", "content": "Neurotoxicologic studies of two carbamate pesticides in subacute animal experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212195"} {"pmid": "4212196", "title": "Neutralization of allotype suppression in rabbits.", "content": "Neutralization of allotype suppression in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212196"} {"pmid": "4212198", "title": "New preclinical safety evaluation for single-dose clinical pharmacology.", "content": "New preclinical safety evaluation for single-dose clinical pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212198"} {"pmid": "4212197", "title": "New phage-SPO1-induced polypeptides associated with Bacillus subtilis RNA polymerase.", "content": "New phage-SPO1-induced polypeptides associated with Bacillus subtilis RNA polymerase. RNA polymerase was precipitated from extracts of Bacillus subtilis infected with phage SP01 by antiserum prepared against core RNA polymerase. As shown by sodium dodecyl sulfate gel electrophoresis, the precipitates contained at least five new polypeptides not present in uninfected bacteria, in addition to the known subunits of RNA polymerase. The molecular weights of these polypeptides are (1) 85,000; (II) 40,000; (III) 28,000; (IV) 25,000; and (V) 23,000. Four of the polypeptides (I, III, IV, and V) co-purified with RNA polymerase through gel filtration and phosphocellulose chromatography. A pulse-chase experiment indicated that all five polypeptides are synthesized de novo after infection. The synthesis of polypeptides II, III, and IV commences almost immediately after infection, while polypeptides I and V first appear several minutes later. A sus mutant blocked early in transcription, susF21 [Fujita, et al. (1971) J. Mol. Biol. 57, 301-317] failed to induce polypeptides I, IV, and V, while two other mutants, susF4 and susF14, blocked late in transcription both failed only to induce polypeptide V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212197"} {"pmid": "4212199", "title": "Newer antibiotic agents acting on gram-negative organisms.", "content": "Newer antibiotic agents acting on gram-negative organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212199"} {"pmid": "4212200", "title": "Non-specific genital infection in a general practice.", "content": "Non-specific genital infection in a general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212200"} {"pmid": "4212201", "title": "Nongonococcal urethritis. A venereal disease as prevalent as epidemic gonorrhea.", "content": "Nongonococcal urethritis. A venereal disease as prevalent as epidemic gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212201"} {"pmid": "4212202", "title": "Nonneurogenic disorders of the anus and rectum.", "content": "Nonneurogenic disorders of the anus and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212202"} {"pmid": "4212203", "title": "Normal factor 8 antigen level in combined congenital deficiency of factor V and factor VIII.", "content": "Normal factor 8 antigen level in combined congenital deficiency of factor V and factor VIII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212203"} {"pmid": "4212204", "title": "Normal reproductive performance of mature cockerels fed Aroclor 1248.", "content": "Normal reproductive performance of mature cockerels fed Aroclor 1248.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212204"} {"pmid": "4212206", "title": "Nuclear segregation in Bacillus subtilis.", "content": "Nuclear segregation in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212206"} {"pmid": "4212205", "title": "Nosema connori n. sp., a microsporidian parasite of man.", "content": "Nosema connori n. sp., a microsporidian parasite of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212205"} {"pmid": "4212207", "title": "Observations on the ecology of Schistosoma mattheei Veglia & Le Roux, 1929, in portion of the Kruger National Park and surrounding area using a new quantitative technique for egg output.", "content": "Observations on the ecology of Schistosoma mattheei Veglia & Le Roux, 1929, in portion of the Kruger National Park and surrounding area using a new quantitative technique for egg output.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212207"} {"pmid": "4212208", "title": "Observations on the mechanism by which T-lymphocytes exert cytotoxic effects.", "content": "Observations on the mechanism by which T-lymphocytes exert cytotoxic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212208"} {"pmid": "4212209", "title": "Occipital lobe epilepsy. A clinical and electroencephalographic study.", "content": "Occipital lobe epilepsy. A clinical and electroencephalographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212209"} {"pmid": "4212210", "title": "On the conformation of thyrotropin releasing hormone.", "content": "On the conformation of thyrotropin releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212210"} {"pmid": "4212211", "title": "One-day oral pivampicillin hydrochloride treatment for acute gonococcal urethritis in male patients.", "content": "One-day oral pivampicillin hydrochloride treatment for acute gonococcal urethritis in male patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212211"} {"pmid": "4212212", "title": "Opiate receptor binding: effects of enzymatic treatments.", "content": "Opiate receptor binding: effects of enzymatic treatments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212212"} {"pmid": "4212213", "title": "Opponent-colour cells in different layers of foveal striate cortex.", "content": "Opponent-colour cells in different layers of foveal striate cortex. 1. The majority of cells in layer 4B have opponent-colour properties indicating that colour opponency plays an important role in the early stages of visual processing in foveal striate cortex. In contrast to cells in the lateral geniculate nucleus many of these cells receive centre-surround antagonism from the same cone mechanism. Some cells show this spatial antagonism at threshold; others require suprathreshold stimuli for its demonstration.2. The majority of cells in layer 4B do not show orientation or directional selectivity. The proportion of cells with orientation and directional selectivity increases and the proportion of opponent-colour cells decreases with increasing distance above and below layer 4B so that the majority of cells in the outer layers exhibit considerable spatial selectivity without apparent colour opponency. These changing proportions suggest that the latter cells may be receiving their inputs from different types of opponent-colour cells making them sensitive to different types of colour contrast but not to colour per se.3. More opponent-colour cells receive inputs from the red- and green- sensitive cone mechanisms than from the blue-sensitive one. This difference is more marked in layer 4B than 3B suggesting that the latter cortical layer may be more involved in colour vision than the former.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212213"} {"pmid": "4212214", "title": "Opthalmologic effect of ultrasound at diagnostic intensities.", "content": "Opthalmologic effect of ultrasound at diagnostic intensities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212214"} {"pmid": "4212215", "title": "Oral and intravenous toxicity of delta9-tetrahydrocannabinol in rhesus monkeys.", "content": "Oral and intravenous toxicity of delta9-tetrahydrocannabinol in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212215"} {"pmid": "4212216", "title": "Orbital apex syndrome complicating frontal pyocoele.", "content": "Orbital apex syndrome complicating frontal pyocoele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212216"} {"pmid": "4212218", "title": "Organic mercury poisoning in children.", "content": "Organic mercury poisoning in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212218"} {"pmid": "4212220", "title": "Os penis.", "content": "Os penis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212220"} {"pmid": "4212219", "title": "Orthophosphate requirement for the formation of phosphoenolpyruvate from pyruvate by enzyme preparations from photosynthetic bacteria.", "content": "Orthophosphate requirement for the formation of phosphoenolpyruvate from pyruvate by enzyme preparations from photosynthetic bacteria. The formation of phosphoenolpyruvate from pyruvate and adenosine 5'-triphosphate by enzymes from photosynthetic bacteria required inorganic phosphate, thus indicating that these organisms utilize pyruvate, orthophosphate dikinase rather than phosphoenolpyruvate synthase in photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212219"} {"pmid": "4212221", "title": "Ovarian serous neoplasms in the Rhesus monkey. Electron microscopical observations.", "content": "Ovarian serous neoplasms in the Rhesus monkey. Electron microscopical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212221"} {"pmid": "4212222", "title": "Ovulation block by indomethacin, an inhibitor of prostaglandin synthesis: a study of its site of action in rats.", "content": "Ovulation block by indomethacin, an inhibitor of prostaglandin synthesis: a study of its site of action in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212222"} {"pmid": "4212223", "title": "Paraquat disposition in rats, guinea pigs and monkeys.", "content": "Paraquat disposition in rats, guinea pigs and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212223"} {"pmid": "4212225", "title": "Partial separation on DEAE-Sephadex of antibodies reactive with plant viruses and their protein subunits.", "content": "Partial separation on DEAE-Sephadex of antibodies reactive with plant viruses and their protein subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212225"} {"pmid": "4212224", "title": "Partial purification of proteins isolated from mammalian cornified cells.", "content": "Partial purification of proteins isolated from mammalian cornified cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212224"} {"pmid": "4212217", "title": "Orbital rhabdomyosarcoma in children.", "content": "Orbital rhabdomyosarcoma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212217"} {"pmid": "4212226", "title": "Patient record systems--the making of a precedent?", "content": "Patient record systems--the making of a precedent?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212226"} {"pmid": "4212227", "title": "Pellicle-associated structures in the amastigote stage of Trypanosoma cruzi and Leishmania species.", "content": "Pellicle-associated structures in the amastigote stage of Trypanosoma cruzi and Leishmania species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212227"} {"pmid": "4212228", "title": "Penicillin and other inhibitory substances in quarter milk samples of cows at slaughter.", "content": "Penicillin and other inhibitory substances in quarter milk samples of cows at slaughter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212228"} {"pmid": "4212229", "title": "Penicillin and épluchage treatment of hepatic actinomycosis.", "content": "Penicillin and épluchage treatment of hepatic actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212229"} {"pmid": "4212230", "title": "Penicillin binding components of bacterial cells and their relationship to the mechanism of penicillin action.", "content": "Penicillin binding components of bacterial cells and their relationship to the mechanism of penicillin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212230"} {"pmid": "4212231", "title": "Penicillium endocarditis of aortic valve prosthesis.", "content": "Penicillium endocarditis of aortic valve prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212231"} {"pmid": "4212232", "title": "Peripheral and cardiac factors in experimental septic shock.", "content": "Peripheral and cardiac factors in experimental septic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212232"} {"pmid": "4212233", "title": "Perspectives in nutrition research.", "content": "Perspectives in nutrition research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212233"} {"pmid": "4212234", "title": "Pharmacokinetic evaluation of anticonvulsants prior to efficacy testing exemplified by carbamazepine in epileptic monkey model.", "content": "Pharmacokinetic evaluation of anticonvulsants prior to efficacy testing exemplified by carbamazepine in epileptic monkey model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212234"} {"pmid": "4212235", "title": "Pharmacokinetics of Aroclor 1254 components after intravenous administration to swine and sheep.", "content": "Pharmacokinetics of Aroclor 1254 components after intravenous administration to swine and sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212235"} {"pmid": "4212236", "title": "Pharmacologic effects of MJ 9022-1, a potential tranquilizing agent.", "content": "Pharmacologic effects of MJ 9022-1, a potential tranquilizing agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212236"} {"pmid": "4212238", "title": "Photo-onycholysis.", "content": "Photo-onycholysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212238"} {"pmid": "4212237", "title": "Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules.", "content": "Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules. Polymorphonuclear leukocytes obtained from sterile peritoneal exudates in rabbits contain two phospholipid-splitting activities (phosphatidylacylhydrolases EC 3.1.1.4), one most active at pH 5.5 and the other between pH 7.2 and 9.0. Hydrolysis of phospholipid was demonstrated using Escherichia coli labeled during growth with [1-(14)C]oleate and then autoclaved to inactivate E. coli phospholipases and to increase the accessibility of the microbial phospholipid substrates. The acid and alkaline phospholipase activities are both membrane bound, calcium dependent, and heat stable, and they appear to be specific for the 2-acyl position of phospholipids. Evidence was also obtained suggesting that the E. coli envelope phospholipids with oleate in position 2 are more readily degraded than those with palmitate. The two activities are associated with azurophilic as well as specific granules (obtained by zonal centrifugation) and with phagosomes (isolated after ingestion of paraffin particles by the granulocytes). Phospholipase A activities at pH 5.5 and pH 7.5 degrade the two major phospholipids of E. coli, phosphatidylethanolamine and phosphatidylglycerol, to the same extent, but the phospholipase activity at acid pH does not hydrolyze micellar dispersions of phosphatidylethanolamine. By contrast, phospholipase A(2) activity at pH 7.5 degrades both types of phosphatidylethanolamine substrates. Heparin and chondroitin sulfate inhibit phospholipase activity at pH 5.5 but have little effect on activity at pH 7.5. All detergents tested inhibited phospholipase activity, and both activities are inhibited by reaction products, free fatty acid and lysophosphatidylethanolamine. This product inhibition is only partially prevented by addition of albumin. Supernatant fractions of granulocyte homogenates contain a heat-labile inhibitor of granule phospholipase activity at pH 7.5. Boiling the fraction not only removes the inhibition but actually results in stimulation of hydrolysis at pH 7.5 as well as pH 5.5. These granule-associated phospholipase A activities of polymorphonuclear leukocytes differ in several of their properties from granule or lysosomal phospholipases of other phagocytic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212237"} {"pmid": "4212239", "title": "Photochemistry of bioactive compounds. Photochemical processes of polychlorinated biphenyls.", "content": "Photochemistry of bioactive compounds. Photochemical processes of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212239"} {"pmid": "4212240", "title": "Photoreduction of dyes catalysed by organic and bio-molecules.", "content": "Photoreduction of dyes catalysed by organic and bio-molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212240"} {"pmid": "4212241", "title": "Physiological effect of protein deficiency with special reference to evaluation of protein nutrition and protein requirement.", "content": "Physiological effect of protein deficiency with special reference to evaluation of protein nutrition and protein requirement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212241"} {"pmid": "4212243", "title": "Pineal structure and function in domestic livestock.", "content": "Pineal structure and function in domestic livestock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212243"} {"pmid": "4212242", "title": "Physiological roles of pneumococcal peptidases.", "content": "Physiological roles of pneumococcal peptidases. A methionyl-specific dipeptidase from Streptococcus pneumoniae has been described. This enzyme and the pneumococcal tripeptidase have been shown to be intracellular, soluble, and constitutive. In addition to their function in cleavage of peptide nutrients, these peptidases may play a role in protein synthesis and turnover.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212242"} {"pmid": "4212244", "title": "Plasma enzyme activities in Coturnix quail fed graded doses of DDE, polychlorinated biphenyl, malathion and mercuric chloride.", "content": "Plasma enzyme activities in Coturnix quail fed graded doses of DDE, polychlorinated biphenyl, malathion and mercuric chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212244"} {"pmid": "4212245", "title": "Plasma triglycerides in human diabetes.", "content": "Plasma triglycerides in human diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212245"} {"pmid": "4212246", "title": "Platelet survival and platelet production in idiopathic thrombocytopenic purpura (ITP).", "content": "Platelet survival and platelet production in idiopathic thrombocytopenic purpura (ITP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212246"} {"pmid": "4212247", "title": "Pleiotropic effects of mutations involved in the regulation of Escherichia coli K-12 alkaline phosphatase.", "content": "Pleiotropic effects of mutations involved in the regulation of Escherichia coli K-12 alkaline phosphatase. Induction of alkaline phosphatase in wild-type Escherichia coli K-12 leads to the appearance of three new proteins in addition to alkaline phosphatase in the periplasmic space of the bacteria. These proteins are detected in autoradiograms of sodium dodecyl sulfate-acrylamide gel electropherograms of extracts from cells labeled with [(35)S]methionine. Studies with constitutive mutants defective in the three genes phoS, phoT, and phoR that have been shown to regulate alkaline phosphatase synthesis indicate that the three periplasmic proteins are coregulated with alkaline phosphatase. A mutant that has a deletion in the alkaline phosphatase structural gene phoA produces the three proteins, but a newly discovered mutant phoB that has a defect in the expression of alkaline phosphatase fails to produce the three proteins. phoB mutants are shown here to be unable to make detectable amounts of alkaline phosphatase polypeptides, as measured by immunoprecipitins or acrylamide gel electropherograms. On the basis of these results we suggest a new model for the regulation of alkaline phosphatase biosynthesis. In this model, a ternary complex composed of phoB(+) and phoR(+) gene products and an internal metabolite functions as a positive control element to regulate the transcription of several cistrons coding for periplasmic proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212247"} {"pmid": "4212249", "title": "Polyglutamyl derivatives of folate as substrates and inhibitors of thymidylate synthetase.", "content": "Polyglutamyl derivatives of folate as substrates and inhibitors of thymidylate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212249"} {"pmid": "4212250", "title": "Polyteny and the functional significance of the polytene cell cycle.", "content": "Polyteny and the functional significance of the polytene cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212250"} {"pmid": "4212248", "title": "Pleiotropic effects of suppressor mutations in Bacillus subtilis.", "content": "Pleiotropic effects of suppressor mutations in Bacillus subtilis. Isogenic strains of Bacillus subtilis carrying sup-1 (26), sup-3 (10), or their wild-type alleles were constructed in three genetic backgrounds. The patterns of suppression at 37 and 43.5 C, identity of mapping site, effects of the suppressor genes on growth rate, sporulation, and production of altered enzymes were examined. The similarity of the suppression pattern by sup-1 and sup-3 suggests that the suppressors are of the same type. They do not, however, represent mutations in the same gene, since, based on differences in temperature sensitivity of phage mutants in suppressor-containing hosts, sup-1 and sup-3 insert different amino acids and can coexist within the same cell. The ability to produce slow-migrating forms of enzymes of the type described in the accompanying paper was co-transferred with either of the suppressor genes during transformation, was lost on reversion of the suppressor mutations, and was independent of the genetic background. Similarly, transformation and reversion studies indicate that the additional pleiotropic properties such as slow growth rate and inability to attain competence or to yield plaques with phi105C4, which are characteristic of the Okubo sup-1 strain (HA101B) but not its early sporulation defect, result from the presence of the suppressor mutation. The possible mechanisms by which altered enzyme forms and the additional pleiotropic effects are produced in suppressor strains are discussed. In addition, a newly recognized suppressor phenotype is described and partially characterized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212248"} {"pmid": "4212251", "title": "Pontomedullary listeriosis in renal allograft recipient.", "content": "Pontomedullary listeriosis in renal allograft recipient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212251"} {"pmid": "4212252", "title": "Possible role of adenosine deaminase in suboptimal growth of the bacillus anthracis adenine auxotroph mutant.", "content": "Possible role of adenosine deaminase in suboptimal growth of the bacillus anthracis adenine auxotroph mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212252"} {"pmid": "4212253", "title": "Potent in vitro inhibitors of tyrosinase: metal-binding fractions of tobacco smoke condensate.", "content": "Potent in vitro inhibitors of tyrosinase: metal-binding fractions of tobacco smoke condensate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212253"} {"pmid": "4212254", "title": "Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells.", "content": "Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212254"} {"pmid": "4212255", "title": "Poverty, pregnancy outcome and child development.", "content": "Poverty, pregnancy outcome and child development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212255"} {"pmid": "4212256", "title": "Practical concepts of drug absorption, distribution and loss.", "content": "Practical concepts of drug absorption, distribution and loss. Serum concentrations of ampicillin were measured following administration of the drug orally and intravenously to nine normal volunteers. The results were analysed by graphic methods, and the effects of absorption, distribution and loss on the time serum concentration curve are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212256"} {"pmid": "4212257", "title": "Practical problems in the organization of a drug trial in two hospital groups.", "content": "Practical problems in the organization of a drug trial in two hospital groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212257"} {"pmid": "4212258", "title": "Preclinical toxicologic evaluation of chromomycin A3 (NSC-58 514) in mice, dogs and monkeys.", "content": "Preclinical toxicologic evaluation of chromomycin A3 (NSC-58 514) in mice, dogs and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212258"} {"pmid": "4212260", "title": "Prepaid group practice and the delivery of ambulatory care.", "content": "Prepaid group practice and the delivery of ambulatory care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212260"} {"pmid": "4212261", "title": "Preparation of a soluble, bifunctional enzyme aggregate and studies on its kinetic behaviour in polymer media.", "content": "Preparation of a soluble, bifunctional enzyme aggregate and studies on its kinetic behaviour in polymer media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212261"} {"pmid": "4212262", "title": "Preparation of antisera against different animal serum proteins, using cross-reacting specific anti-human sera.", "content": "Preparation of antisera against different animal serum proteins, using cross-reacting specific anti-human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212262"} {"pmid": "4212263", "title": "Preparation of tRNA's and aminoacyl-tRNA synthetases from Bacillus subtilis cells at various stages of growth and spores.", "content": "Preparation of tRNA's and aminoacyl-tRNA synthetases from Bacillus subtilis cells at various stages of growth and spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212263"} {"pmid": "4212264", "title": "Preparation of vaccines--cell substrates.", "content": "Preparation of vaccines--cell substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212264"} {"pmid": "4212265", "title": "Presence of amino acid dehydrogenases and transaminases in Myxococcus xanthus during vegetative growth and myxospore formation.", "content": "Presence of amino acid dehydrogenases and transaminases in Myxococcus xanthus during vegetative growth and myxospore formation. The following enzymatic activities were demonstrated in Myxococcus xanthus during growth and myxospore formation: l-alanine dehydrogenase (EC 1.4.1.1), l-glutamic acid dehydrogenase (EC 1.4.1.2), glycine dehydrogenase (EC 1.4.1.5), l-glutamic glyoxylate aminotransferase (EC 2.6.1.4), and l-alanine glyoxylate aminotransferase (EC 2.6.1.12).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212265"} {"pmid": "4212266", "title": "Pressure-induced dissociation of ribosomes.", "content": "Pressure-induced dissociation of ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212266"} {"pmid": "4212259", "title": "Preliminary observations on antigen activity of Fasciola gigantica by immunodiffusion test in sheep.", "content": "Preliminary observations on antigen activity of Fasciola gigantica by immunodiffusion test in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212259"} {"pmid": "4212267", "title": "Prevalence of irregular red cell antibodies and their significance in blood transfusion and antenatal care.", "content": "Prevalence of irregular red cell antibodies and their significance in blood transfusion and antenatal care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212267"} {"pmid": "4212268", "title": "Private practice dentists--fight back. 2.", "content": "Private practice dentists--fight back. 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212268"} {"pmid": "4212270", "title": "Proceedings: Mechanism of insulin release: an approach to the mode of action of sulfonylurea.", "content": "Proceedings: Mechanism of insulin release: an approach to the mode of action of sulfonylurea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212270"} {"pmid": "4212269", "title": "Problems in cell wall assembly.", "content": "Problems in cell wall assembly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212269"} {"pmid": "4212271", "title": "Proceedings: Psychological tests and drugs.", "content": "Proceedings: Psychological tests and drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212271"} {"pmid": "4212272", "title": "Proceedings: Some aspects of trophism in amphibian slow muscle fibres.", "content": "Proceedings: Some aspects of trophism in amphibian slow muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212272"} {"pmid": "4212273", "title": "Production of hyperimmune serum against collagen and its use for the isolation of specific collagen peptides on immunosorbent columns.", "content": "Production of hyperimmune serum against collagen and its use for the isolation of specific collagen peptides on immunosorbent columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212273"} {"pmid": "4212274", "title": "Prognostic value of urography in irradiated cervical carcinoma.", "content": "Prognostic value of urography in irradiated cervical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212274"} {"pmid": "4212275", "title": "Propagation and plaquing of Dugbe virus (an ungrouped Nigerian arbovirus) in various mammalian and arthropod cell lines.", "content": "Propagation and plaquing of Dugbe virus (an ungrouped Nigerian arbovirus) in various mammalian and arthropod cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212275"} {"pmid": "4212276", "title": "Propanidid in epilepsy.", "content": "Propanidid in epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212276"} {"pmid": "4212277", "title": "Properties and inhibition of thymidylate synthetase in Drosophila melanogaster.", "content": "Properties and inhibition of thymidylate synthetase in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212277"} {"pmid": "4212278", "title": "Prostaglandin F in the peripheral plasma of the rhesus monkey in normal pregnancy and after the administration of dexamethasone and PGF2 alpha.", "content": "Prostaglandin F in the peripheral plasma of the rhesus monkey in normal pregnancy and after the administration of dexamethasone and PGF2 alpha.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212278"} {"pmid": "4212280", "title": "Protection of rats from experimental allergic encephalomyelitis with antiserum to guinea-pig spinal cord.", "content": "Protection of rats from experimental allergic encephalomyelitis with antiserum to guinea-pig spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212280"} {"pmid": "4212281", "title": "Protein synthesis in Bacillus subtilis: differential effect of potassium ions on in vitro peptide chain initiation and elongation.", "content": "Protein synthesis in Bacillus subtilis: differential effect of potassium ions on in vitro peptide chain initiation and elongation. The preparation and fractionation of a highly active and stable in vitro protein-synthesizing system from Bacillus subtilis is described. Potassium satisfied the requirement for a monovalent ion when the initiation factor-dependent binding of formyl-methionyl-transfer ribonucleic acid and synthesis of formyl-methionyl-puromycin were assayed, whereas it inhibited the reactions for polyphenylalanine synthesis. On the other hand, the ammonium ion satisfied the requirement for all assayed reactions. The in vitro experimental evidence suggested that potassium is an inhibitor of one or a few specific reactions involved in peptide chain elongation in B. subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212281"} {"pmid": "4212282", "title": "Proteins in fluid from non-keratinizing jaw cysts. 3. Identification of individual proteins with particular reference to alpha- and beta-globulins, including fibrinogen.", "content": "Proteins in fluid from non-keratinizing jaw cysts. 3. Identification of individual proteins with particular reference to alpha- and beta-globulins, including fibrinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212282"} {"pmid": "4212283", "title": "Proton magnetic resonance studies of intracellular water in sickle cells.", "content": "Proton magnetic resonance studies of intracellular water in sickle cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212283"} {"pmid": "4212285", "title": "Pulmonary edema following generalized convulsions (postictal).", "content": "Pulmonary edema following generalized convulsions (postictal).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212285"} {"pmid": "4212287", "title": "Purification and partial characterization of protease from calf thymus chromatin.", "content": "Purification and partial characterization of protease from calf thymus chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212287"} {"pmid": "4212286", "title": "Purification and characterization of Streptococcus mutans group d cell wall polysaccharide antigen.", "content": "Purification and characterization of Streptococcus mutans group d cell wall polysaccharide antigen. The Streptococcus mutans group d antigen of strain B13 has been purified and characterized with respect to chemical composition and immunochemical properties. The antigen was extracted from lyophilized cells or cell walls by using 5% trichloroacetic acid at 5 C for 16 h. The antigen could also be extracted with water or 0.01 N HCl at 100 C for 20 min. The antigen was purified by ion-exchange and gel chromatography and was found to contain 96% carbohydrate, 1.6% protein, and 0.3% phosphorus. Characterization by gas chromatography indicated that the polysaccharide was composed of galactose and glucose in a 2:1 ratio. The antigen contained two serologically active sites: one site specific for group d and a second site common to both group d and group a strains. Agar diffusion and immunoelectrophoresis indicated that the two sites existed on a single molecule. The immunological specificity of the group d polysaccharide site depended on a terminal d-galactose. The purified B13 antigen did not react with antisera specific for the glycerol teichoic acid from streptococci. Anti-d serum rapidly agglutinated whole cells, indicating that the antibody receptor sites of the polysaccharide antigen were at the surface of the streptococcal cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212286"} {"pmid": "4212288", "title": "Purification and properties of an extracellular proteinase of psychrophilic Escherichia freundii.", "content": "Purification and properties of an extracellular proteinase of psychrophilic Escherichia freundii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212288"} {"pmid": "4212289", "title": "Purification and properties of interference factor I: a cistron-specific translation control factor and a subunit of phage RNA replicase.", "content": "Purification and properties of interference factor I: a cistron-specific translation control factor and a subunit of phage RNA replicase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212289"} {"pmid": "4212284", "title": "Psychopharmacology of the cannabinoids. A review.", "content": "Psychopharmacology of the cannabinoids. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212284"} {"pmid": "4212290", "title": "Purification and properties of AMP-aminohydrolase from human placenta.", "content": "Purification and properties of AMP-aminohydrolase from human placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212290"} {"pmid": "4212291", "title": "Purification of TF1--a template-specific DNA-binding protein and transcription inhibitor from Bacteriophage SPO1-infected Bacillus subtilis.", "content": "Purification of TF1--a template-specific DNA-binding protein and transcription inhibitor from Bacteriophage SPO1-infected Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212291"} {"pmid": "4212279", "title": "Protection by disodium cromoglycate in airways diseases.", "content": "Protection by disodium cromoglycate in airways diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212279"} {"pmid": "4212292", "title": "Pyrroles and related compounds. XXXII. Biosynthesis of protoporphyrin-IX from coproporphyrinogen-3.", "content": "Pyrroles and related compounds. XXXII. Biosynthesis of protoporphyrin-IX from coproporphyrinogen-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212292"} {"pmid": "4212294", "title": "Quantification of the pituitary-thyroid axis in pregnant rats.", "content": "Quantification of the pituitary-thyroid axis in pregnant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212294"} {"pmid": "4212293", "title": "Pyruvate formate lyase in Rhodospirillum rubrum Ha adapted to anaerobic dark conditions.", "content": "Pyruvate formate lyase in Rhodospirillum rubrum Ha adapted to anaerobic dark conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212293"} {"pmid": "4212295", "title": "Quantitative and comparative studies of pharmacological features in the coronary, femoral and renal circulations with different coronary vasodilators.", "content": "Quantitative and comparative studies of pharmacological features in the coronary, femoral and renal circulations with different coronary vasodilators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212295"} {"pmid": "4212296", "title": "Radiation sterilization and the anesthetist.", "content": "Radiation sterilization and the anesthetist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212296"} {"pmid": "4212297", "title": "Radiation-induced nondisjunction and Robertsonian translocation in Drosophila.", "content": "Radiation-induced nondisjunction and Robertsonian translocation in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212297"} {"pmid": "4212298", "title": "Radioimmunoassay of parathyroid hormone: peripheral plasma immunoreactive parathyroid hormone response to ethylenediaminetetraacetate.", "content": "Radioimmunoassay of parathyroid hormone: peripheral plasma immunoreactive parathyroid hormone response to ethylenediaminetetraacetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212298"} {"pmid": "4212299", "title": "Rapid screening tests for the diagnosis of bovine brucellosis by the complement fixation test.", "content": "Rapid screening tests for the diagnosis of bovine brucellosis by the complement fixation test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212299"} {"pmid": "4212300", "title": "Rapid transfer of folic acid from blood to bile in man, and its conversion into folate coenzymes and into a pteroylglutamate with little biological activity.", "content": "Rapid transfer of folic acid from blood to bile in man, and its conversion into folate coenzymes and into a pteroylglutamate with little biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212300"} {"pmid": "4212302", "title": "Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro.", "content": "Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212302"} {"pmid": "4212301", "title": "Rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: a comparison and immunological study of purified solubilized preparations, and alteration of enzyme levels by cholestyramine feeding.", "content": "Rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: a comparison and immunological study of purified solubilized preparations, and alteration of enzyme levels by cholestyramine feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212301"} {"pmid": "4212303", "title": "Recent trends of isolates from cases of bacteremia in Denmark.", "content": "Recent trends of isolates from cases of bacteremia in Denmark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212303"} {"pmid": "4212304", "title": "Recognition of two distinct groups of human IgM and IgA based on different binding to staphylococci.", "content": "Recognition of two distinct groups of human IgM and IgA based on different binding to staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212304"} {"pmid": "4212305", "title": "Reconstitution of spinach ribulose-1,5-diphosphate carboxylase from departed subunits.", "content": "Reconstitution of spinach ribulose-1,5-diphosphate carboxylase from departed subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212305"} {"pmid": "4212306", "title": "Recovery from long-term protein-energy deficiency.", "content": "Recovery from long-term protein-energy deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212306"} {"pmid": "4212308", "title": "Red cell life span in sickle cell trait.", "content": "Red cell life span in sickle cell trait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212308"} {"pmid": "4212307", "title": "Red cell and serum proteins of patas monkeys, Cercopithecus (equal Erythrocebus) patas.", "content": "Red cell and serum proteins of patas monkeys, Cercopithecus (equal Erythrocebus) patas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212307"} {"pmid": "4212309", "title": "Regional distribution of homocarnosine and other ninhydrin-positive substances in brains of malnourished monkeys.", "content": "Regional distribution of homocarnosine and other ninhydrin-positive substances in brains of malnourished monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212309"} {"pmid": "4212310", "title": "Regulation of glucosylation of teichoic acid. I. Isolation of phosphoglucomutase in Bacillus subtilis 168.", "content": "Regulation of glucosylation of teichoic acid. I. Isolation of phosphoglucomutase in Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212310"} {"pmid": "4212311", "title": "Regulation of glucosylation of teichoic acid. II. Partial characterization of phosphoglucomutase in Bacillus subtilis 168.", "content": "Regulation of glucosylation of teichoic acid. II. Partial characterization of phosphoglucomutase in Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212311"} {"pmid": "4212312", "title": "Regulation of rat liver glycogen synthetase D. Role of glucose 6-phosphate and enzyme sulfhydryl groups in activity and glycogen binding.", "content": "Regulation of rat liver glycogen synthetase D. Role of glucose 6-phosphate and enzyme sulfhydryl groups in activity and glycogen binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212312"} {"pmid": "4212313", "title": "Regulation of ribosome content in eukaryotes.", "content": "Regulation of ribosome content in eukaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212313"} {"pmid": "4212314", "title": "Reinvestigation of the physicochemical and enzymic properties of L-glutaminase from Pseudomonas.", "content": "Reinvestigation of the physicochemical and enzymic properties of L-glutaminase from Pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212314"} {"pmid": "4212316", "title": "Relationships between inhibition constants and fractional inhibition in enzyme-catalyzed reactions with different numbers of reactants, different reaction mechanisms, and different types and mechanisms of inhibition.", "content": "Relationships between inhibition constants and fractional inhibition in enzyme-catalyzed reactions with different numbers of reactants, different reaction mechanisms, and different types and mechanisms of inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212316"} {"pmid": "4212315", "title": "Relationship of oculomotor nuclei to midbrain reticular formation.", "content": "Relationship of oculomotor nuclei to midbrain reticular formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212315"} {"pmid": "4212317", "title": "Release of mRNP-particles of the informosome type from polyribosomes of higher plant embryos.", "content": "Release of mRNP-particles of the informosome type from polyribosomes of higher plant embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212317"} {"pmid": "4212318", "title": "Removal of organochlorine pesticides and polychlorinated biphenyls from marine oils during refining and hydrogenation for edible use.", "content": "Removal of organochlorine pesticides and polychlorinated biphenyls from marine oils during refining and hydrogenation for edible use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212318"} {"pmid": "4212319", "title": "Resistance to Listeria monocytogenes of guinea pigs sensitized with a simple protein.", "content": "Resistance to Listeria monocytogenes of guinea pigs sensitized with a simple protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212319"} {"pmid": "4212321", "title": "Results of combination chemotherapy, surgery, and radiotherapy in children with neuroblastoma.", "content": "Results of combination chemotherapy, surgery, and radiotherapy in children with neuroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212321"} {"pmid": "4212320", "title": "Responses to acoustic stimuli of units in the auditory cortex of awake squirrel monkeys.", "content": "Responses to acoustic stimuli of units in the auditory cortex of awake squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212320"} {"pmid": "4212322", "title": "Reversed haemagglutination tests for the detection of hepatitis B antigen.", "content": "Reversed haemagglutination tests for the detection of hepatitis B antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212322"} {"pmid": "4212323", "title": "Reversible inactivation by ammonia of assimilatory nitrate reductase in Cyanidium caldarium.", "content": "Reversible inactivation by ammonia of assimilatory nitrate reductase in Cyanidium caldarium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212323"} {"pmid": "4212325", "title": "Role of metabolic disorders of thyroid hormones in the pathogenesis of diabetes mellitus.", "content": "Role of metabolic disorders of thyroid hormones in the pathogenesis of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212325"} {"pmid": "4212324", "title": "Rifampicin in plasma and pleural fluid after single oral doses.", "content": "Rifampicin in plasma and pleural fluid after single oral doses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212324"} {"pmid": "4212327", "title": "Role of physical and neuroendocrine factors in proximal electrolyte reabsorption.", "content": "Role of physical and neuroendocrine factors in proximal electrolyte reabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212327"} {"pmid": "4212328", "title": "Role of singlet oxygen in some chemiluminescence and enzyme oxidation reactions.", "content": "Role of singlet oxygen in some chemiluminescence and enzyme oxidation reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212328"} {"pmid": "4212330", "title": "Role of the heart in the pathogenesis of endotoxin shock. A review of the clinical findings and observations on animal species.", "content": "Role of the heart in the pathogenesis of endotoxin shock. A review of the clinical findings and observations on animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212330"} {"pmid": "4212331", "title": "Schizogony of Toxoplasma gondii in tissue cultures.", "content": "Schizogony of Toxoplasma gondii in tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212331"} {"pmid": "4212332", "title": "Seasonal variation in serum ascorbic acid and serum lipid composition of free-living baboons (Papio ursinus).", "content": "Seasonal variation in serum ascorbic acid and serum lipid composition of free-living baboons (Papio ursinus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212332"} {"pmid": "4212333", "title": "Selective action of isoniazid on the synthesis of cell wall mycolates in mycobacteria.", "content": "Selective action of isoniazid on the synthesis of cell wall mycolates in mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212333"} {"pmid": "4212335", "title": "Self administration: positive and negative reinforcing properties of morphine antagonists in rhesus monkeys.", "content": "Self administration: positive and negative reinforcing properties of morphine antagonists in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212335"} {"pmid": "4212334", "title": "Selective IgA deficiency in Rh-negative women.", "content": "Selective IgA deficiency in Rh-negative women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212334"} {"pmid": "4212326", "title": "Role of packaging in ethylene oxide sterilization.", "content": "Role of packaging in ethylene oxide sterilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212326"} {"pmid": "4212336", "title": "Serological techniques for the detection of antibodies to porcine thrombocytes. I. The agglutination, fluorescent antibody and immunodiffusion techniques.", "content": "Serological techniques for the detection of antibodies to porcine thrombocytes. I. The agglutination, fluorescent antibody and immunodiffusion techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212336"} {"pmid": "4212338", "title": "Simian lymphography.", "content": "Simian lymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212338"} {"pmid": "4212329", "title": "Role of some macro and microelements on the nitrogen fixation by the blue-green alga Calothrix sp.", "content": "Role of some macro and microelements on the nitrogen fixation by the blue-green alga Calothrix sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212329"} {"pmid": "4212339", "title": "Size of the chromosome of Pseudomonas aeruginosa PAO.", "content": "Size of the chromosome of Pseudomonas aeruginosa PAO. Electron microscope examination and velocity sedimentation analysis of the deoxyribonucleic acid released from Pseudomonas aeruginosa spheroplasts indicate that this organism carries the bulk of its genetic determinants in a single duplex deoxyribonucleic acid molecule having a molecular mass of 2.1 x 10(9) daltons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212339"} {"pmid": "4212340", "title": "Snake venom toxins. The reactivity of the disulphide bonds of Naja nivea toxin alpha.", "content": "Snake venom toxins. The reactivity of the disulphide bonds of Naja nivea toxin alpha.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212340"} {"pmid": "4212342", "title": "Sodium cromoglycate: a clinical view.", "content": "Sodium cromoglycate: a clinical view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212342"} {"pmid": "4212343", "title": "Solubilization and partial purification of alkaline phosphatases of sarcoma 180-TG ascites cells.", "content": "Solubilization and partial purification of alkaline phosphatases of sarcoma 180-TG ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212343"} {"pmid": "4212344", "title": "Some in vitro effects of synthetic thyrotrophin releasing factor on the secretion of thyroid stimulating hormone from the anterior pituitary gland of the domestic fowl.", "content": "Some in vitro effects of synthetic thyrotrophin releasing factor on the secretion of thyroid stimulating hormone from the anterior pituitary gland of the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212344"} {"pmid": "4212346", "title": "Spectrophotometric titration of edetic acid in ophthalmic solutions.", "content": "Spectrophotometric titration of edetic acid in ophthalmic solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212346"} {"pmid": "4212345", "title": "Some properties of the liver-specific delta autoantigen of the rat.", "content": "Some properties of the liver-specific delta autoantigen of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212345"} {"pmid": "4212347", "title": "Spinach leaf phosphoenolpyruvate carboxylase: purification, properties, and kinetic studies.", "content": "Spinach leaf phosphoenolpyruvate carboxylase: purification, properties, and kinetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212347"} {"pmid": "4212348", "title": "Spinal cord injury clinic: an approach to long-term health maintenance in the individual with spinal cord injury.", "content": "Spinal cord injury clinic: an approach to long-term health maintenance in the individual with spinal cord injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212348"} {"pmid": "4212341", "title": "Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use.", "content": "Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212341"} {"pmid": "4212349", "title": "Stability of certain amino acids in a parenteral nutrition solution.", "content": "Stability of certain amino acids in a parenteral nutrition solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212349"} {"pmid": "4212350", "title": "Standardization of the basic concepts in electron microscopic autoradiography.", "content": "Standardization of the basic concepts in electron microscopic autoradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212350"} {"pmid": "4212351", "title": "Starvation and the glycogen of the brain and vital organs of the rhesus monkey.", "content": "Starvation and the glycogen of the brain and vital organs of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212351"} {"pmid": "4212352", "title": "Statistical estimate of the total number of operons specific for Bacillus subtilis sporulation.", "content": "Statistical estimate of the total number of operons specific for Bacillus subtilis sporulation. As an alternative to exhaustive mapping, an attempt has been made to obtain a rough estimate of the total number of sporulation operons by statistical treatment. Sixteen sporulation mutants taken at random were characterized biochemically and morphologically. The mutations they contained were mapped to determine whether they fell into any one of 23 known operons. From the proportion that do so (10/16), it is calculated that the most probable number of sporulation operons is 37 (68% confidence limits of 31 and 46). If allowance is made for the fact that two of the operons apparently contain mutagenic \"hot spots\" and the calculation is amended accordingly, the most probable numbers of operons becomes 42 (limits 33 and 59).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212352"} {"pmid": "4212353", "title": "Stones in common bile duct: non-operative management.", "content": "Stones in common bile duct: non-operative management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212353"} {"pmid": "4212354", "title": "Structural and immunologic characteristics of subviral components of Sindbis, eastern equine and western equine encephalitis viruses.", "content": "Structural and immunologic characteristics of subviral components of Sindbis, eastern equine and western equine encephalitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212354"} {"pmid": "4212355", "title": "Structure of haemoglobin Wien beta 130 (H8) tyrosine-aspartic acid: an unstable haemoglobin variant.", "content": "Structure of haemoglobin Wien beta 130 (H8) tyrosine-aspartic acid: an unstable haemoglobin variant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212355"} {"pmid": "4212356", "title": "Structure of the oocyst and excystation of sporozoites of Isospora endocallimici n. sp., from the marmoset Callimico goeldii.", "content": "Structure of the oocyst and excystation of sporozoites of Isospora endocallimici n. sp., from the marmoset Callimico goeldii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212356"} {"pmid": "4212357", "title": "Structure-activity relationships in narcotic antagonists with N-furylmethyl substituents.", "content": "Structure-activity relationships in narcotic antagonists with N-furylmethyl substituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212357"} {"pmid": "4212359", "title": "Studies of folate compounds in nature. Folate compounds in rat kidney and red blood cells.", "content": "Studies of folate compounds in nature. Folate compounds in rat kidney and red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212359"} {"pmid": "4212358", "title": "Studies of bactericidal activity to Escherichia coli of porcine serum and colostral immunoglobulins and the role of lysozyme with secretory IgA.", "content": "Studies of bactericidal activity to Escherichia coli of porcine serum and colostral immunoglobulins and the role of lysozyme with secretory IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212358"} {"pmid": "4212360", "title": "Studies of human kidney antigens.", "content": "Studies of human kidney antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212360"} {"pmid": "4212361", "title": "Studies of prostaglandins and prostaglandin antagonists on bovine pulmonary vein in vitro.", "content": "Studies of prostaglandins and prostaglandin antagonists on bovine pulmonary vein in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212361"} {"pmid": "4212362", "title": "Studies of Pseudomonas aeruginosa infections among hospitalized patients. I. Isolation and identification of nonfermentative gram-negative rods.", "content": "Studies of Pseudomonas aeruginosa infections among hospitalized patients. I. Isolation and identification of nonfermentative gram-negative rods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212362"} {"pmid": "4212363", "title": "Studies on liver aldolases in hereditary fructose intolerance.", "content": "Studies on liver aldolases in hereditary fructose intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212363"} {"pmid": "4212364", "title": "Studies on slices and isolated cells from fresh osteoarthritic human bone.", "content": "Studies on slices and isolated cells from fresh osteoarthritic human bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212364"} {"pmid": "4212365", "title": "Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 1. The effect of variations in cultivation conditions and the screening of various enzyme specificities.", "content": "Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 1. The effect of variations in cultivation conditions and the screening of various enzyme specificities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212365"} {"pmid": "4212366", "title": "Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 2. Fractionation on ion-exchange chromatography and gel filtration.", "content": "Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 2. Fractionation on ion-exchange chromatography and gel filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212366"} {"pmid": "4212367", "title": "Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 3. Affinity for chitin.", "content": "Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 3. Affinity for chitin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212367"} {"pmid": "4212369", "title": "Studies on the exoerythrocytic stages of simian malaria. IX. Plasmodium simium.", "content": "Studies on the exoerythrocytic stages of simian malaria. IX. Plasmodium simium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212369"} {"pmid": "4212368", "title": "Studies on the control of development. In vitro synthesis of HPN and MS nucleotides by ribosomes from either sporulating or vegetative cells of Bacillus subtilis.", "content": "Studies on the control of development. In vitro synthesis of HPN and MS nucleotides by ribosomes from either sporulating or vegetative cells of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212368"} {"pmid": "4212370", "title": "Studies on the inhibition of oxotremorine induced tremor by a melanocyte-stimulating hormone release-inhibiting factor, thyrotropin releasing hormone and related peptides.", "content": "Studies on the inhibition of oxotremorine induced tremor by a melanocyte-stimulating hormone release-inhibiting factor, thyrotropin releasing hormone and related peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212370"} {"pmid": "4212371", "title": "Studies on the phosphorylation of nucleolar proteins. Comparison of the phosphorylation patterns of nuclear and nucleolar proteins labeled in vivo and in vitro.", "content": "Studies on the phosphorylation of nucleolar proteins. Comparison of the phosphorylation patterns of nuclear and nucleolar proteins labeled in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212371"} {"pmid": "4212372", "title": "Studies on C4 inactivator induced by adenoviruses in KB cell cultures.", "content": "Studies on C4 inactivator induced by adenoviruses in KB cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212372"} {"pmid": "4212373", "title": "Study on the in vitro Rieder cell.", "content": "Study on the in vitro Rieder cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212373"} {"pmid": "4212374", "title": "Subcellular localization and properties of thymidine kinase from adenovirus-infected cells.", "content": "Subcellular localization and properties of thymidine kinase from adenovirus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212374"} {"pmid": "4212375", "title": "Subtype of affective psychoses classified by response on amineprecursors and monoamine metabolism.", "content": "Subtype of affective psychoses classified by response on amineprecursors and monoamine metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212375"} {"pmid": "4212379", "title": "Synthesis and resolution of vinylglycine, a beta,gamma-unsaturated alpha-amino acid.", "content": "Synthesis and resolution of vinylglycine, a beta,gamma-unsaturated alpha-amino acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212379"} {"pmid": "4212378", "title": "Synergistic action of increased oxygen tensions and PABA-folic acid antagonists on bacterial growth.", "content": "Synergistic action of increased oxygen tensions and PABA-folic acid antagonists on bacterial growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212378"} {"pmid": "4212381", "title": "T cell recognition of cell-surface antigens. II. Antigen recognition is necessary yet not sufficient for triggering T cell-mediated immunity.", "content": "T cell recognition of cell-surface antigens. II. Antigen recognition is necessary yet not sufficient for triggering T cell-mediated immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212381"} {"pmid": "4212380", "title": "Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster.", "content": "Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212380"} {"pmid": "4212382", "title": "Target calcifications of the spleen in chronic brucellosis (Brucella suis).", "content": "Target calcifications of the spleen in chronic brucellosis (Brucella suis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212382"} {"pmid": "4212383", "title": "Temperature-sensitive bobbed mutants in Drosophila melanogaster.", "content": "Temperature-sensitive bobbed mutants in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212383"} {"pmid": "4212384", "title": "Terrestrial adaptations in the hands of Cercopithecinae.", "content": "Terrestrial adaptations in the hands of Cercopithecinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212384"} {"pmid": "4212386", "title": "The actions of narcotic antagonists in morphine-dependent rhesus monkeys.", "content": "The actions of narcotic antagonists in morphine-dependent rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212386"} {"pmid": "4212377", "title": "Synaptic alterations in developing cortical infarction: an experimental investigation in monkeys.", "content": "Synaptic alterations in developing cortical infarction: an experimental investigation in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212377"} {"pmid": "4212376", "title": "Surgical correction of subglottic stenosis of the larynx in infants and children. Progress report.", "content": "Surgical correction of subglottic stenosis of the larynx in infants and children. Progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212376"} {"pmid": "4212385", "title": "The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria.", "content": "The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. We have investigated whether mammalian cells can repair pyrimidine dimers in their mitochondrial DNA which have been induced by ultraviolet light. The assay system is based upon the ability of the phage T4 UV endonuclease to nick covalently closed circular mitochondrial DNA that contain pyrimidine dimers. Our results show that dimers are not removed from the mitochondrial DNA of mouse L cells or human KB and HeLa cells. There is also no evidence for photoreactivation of mitochondrial DNA. Analyses of ethidium bromide-cesium chloride equilibrium density gradients of mitochondrial DNA isotopically labeled before and after exposure to ultraviolet light show that the total amount of DNA replication is depressed after exposure. In addition, an increase in the frequency of molecules banding at a position expected for intermediate replicating forms and open circular daughter molecules suggests that the rate of replication is slower (or arrested) in molecules with pyrimidine dimers. The absence of a significant amount of mixing of label incorporated before and after ultraviolet-irradiation is evidence against the occurrence of a large amount of genetic exchange between mitochondrial DNA molecules under these conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212385"} {"pmid": "4212387", "title": "The activation of Cls with purified Clr.", "content": "The activation of Cls with purified Clr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212387"} {"pmid": "4212388", "title": "The anti-Rho(D) responses of immunized volunteers following spaced antigenic stimuli.", "content": "The anti-Rho(D) responses of immunized volunteers following spaced antigenic stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212388"} {"pmid": "4212389", "title": "The antibody response to different measles virus antigens under various conditions of immunization.", "content": "The antibody response to different measles virus antigens under various conditions of immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212389"} {"pmid": "4212391", "title": "The barrier function of the gram-negative envelope.", "content": "The barrier function of the gram-negative envelope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212391"} {"pmid": "4212392", "title": "The cancer syndrome.", "content": "The cancer syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212392"} {"pmid": "4212393", "title": "The cat eye syndrome.", "content": "The cat eye syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212393"} {"pmid": "4212394", "title": "The cerebro-oculo-facio-skeletal syndrome.", "content": "The cerebro-oculo-facio-skeletal syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212394"} {"pmid": "4212395", "title": "The characterization of ribosomal subunits of eukaryotes by ultracentrifugal techniques. Criteria of purity.", "content": "The characterization of ribosomal subunits of eukaryotes by ultracentrifugal techniques. Criteria of purity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212395"} {"pmid": "4212396", "title": "The circular dichroism of a Drosophila melanogaster satellite DNA.", "content": "The circular dichroism of a Drosophila melanogaster satellite DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212396"} {"pmid": "4212390", "title": "The application of an indirect method of infecting ticks with piroplasms for use in the isolation of field infections.", "content": "The application of an indirect method of infecting ticks with piroplasms for use in the isolation of field infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212390"} {"pmid": "4212398", "title": "The decline of cell-mediated immunity in aging mice.", "content": "The decline of cell-mediated immunity in aging mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212398"} {"pmid": "4212397", "title": "The concentrations of progesterone, estrone and estradiol-17 beta in the peripheral plasma of the rhesus monkey during the final third of gestation, and after the induction of abortion with PGF 2 alpha.", "content": "The concentrations of progesterone, estrone and estradiol-17 beta in the peripheral plasma of the rhesus monkey during the final third of gestation, and after the induction of abortion with PGF 2 alpha.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212397"} {"pmid": "4212399", "title": "The double hemidesmosome: a new intercellular junction (1).", "content": "The double hemidesmosome: a new intercellular junction (1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212399"} {"pmid": "4212400", "title": "The ecology of chigger-borne rickettsiosis (scrub typhus).", "content": "The ecology of chigger-borne rickettsiosis (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212400"} {"pmid": "4212401", "title": "The effect of ambient temperature on the anti-D assay using the Auto-Analyzer.", "content": "The effect of ambient temperature on the anti-D assay using the Auto-Analyzer. Using the AutoAnalyzer, the percentage agglutination effected by the anti-D antisera studied showed a varied dependence on the ambient temperature over the manifold subsequent to the incubation period at 37 degrees C. This leads to assays which are a function of the ambient temperature. It is suggested that the entry of a relatively large volume of rouleaux-dispersing agent results in an elution of bound antibody to a new position of equilibrium, the shift being dependent on the particular equilibrium constant of the antibody and the rate of its attainment on the ambient temperature. A constant ambient temperature will lead to greater accuracy of anti-D assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212401"} {"pmid": "4212403", "title": "The effect of dopamine on gastric adrenergic receptors in the goat.", "content": "The effect of dopamine on gastric adrenergic receptors in the goat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212403"} {"pmid": "4212402", "title": "The effect of different serum concentrations of antimicrobial agents on the Lactobacillus casei folate assay.", "content": "The effect of different serum concentrations of antimicrobial agents on the Lactobacillus casei folate assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212402"} {"pmid": "4212404", "title": "The effect of efferent duct ligation on the uptake of 65-ZN by the epididymis and vas deferens of rhesus monkeys (Macaca mulatta).", "content": "The effect of efferent duct ligation on the uptake of 65-ZN by the epididymis and vas deferens of rhesus monkeys (Macaca mulatta). A study dealing with the uptake of zinc-65 by different segments of the epididymis and vas deferens of the rhesus monkey (Macaca mulatta) in the presence or absence of spermatozoa is reported. It was determined that zinc-65 uptake by the vas deferens of the control side was significantly higher than that of the epididymal segments (vas deferens vs. caput, proximal and distal corpus, or cauda, p less than .01). Amon g the epididymal segments themselves there was no significant difference . Efferent duct ligation consistently reduced the uptake of zinc-65 in all portions of the epididymis and vas deferens (control vs. ligated: caput, corpus, cauda, and vas, p less than .01). The percentage reduction in the uptake by different segments of the epididymis and vas remained virtually constant in the ligated side (caput, 57%; proximal corpus, 53%; distal corpus, 64%; cauda, 55%; vas deferens, 55%). Nevertheless, zinc-65 uptake by vas continued to be significantly greater than that of the epididymis. It is noted that the reduced zinc-65 accumulated on the ligated side could at least be partly due to absence of spermatozoa. It is further suggested that the lowered uptake of zinc-65 by the epididymis and vas deferens following efferent duct ligation in the monkey may be also due to a local androgen deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212404"} {"pmid": "4212405", "title": "The effect of hydergine on the transit time of cerebral circulation in diffuse cerebral insufficiency.", "content": "The effect of hydergine on the transit time of cerebral circulation in diffuse cerebral insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212405"} {"pmid": "4212406", "title": "The effect of inferotemporal lesions on memory for visual stimuli in rhesus monkeys.", "content": "The effect of inferotemporal lesions on memory for visual stimuli in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212406"} {"pmid": "4212408", "title": "The effect of intragastric pH variations on the gastric acid response to sham feeding in duodenal ulcer patients.", "content": "The effect of intragastric pH variations on the gastric acid response to sham feeding in duodenal ulcer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212408"} {"pmid": "4212407", "title": "The effect of insulin on the permeability of phosphatidyl choline bimolecular membranes to glucose.", "content": "The effect of insulin on the permeability of phosphatidyl choline bimolecular membranes to glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212407"} {"pmid": "4212409", "title": "The effect of minocycline on Candida albicans.", "content": "The effect of minocycline on Candida albicans. Minocycline, a new tetracycline derivative, was found to inhibit the growth of Candida albicans. Inhibition was much affected by the composition of the medium and was difficult to demonstrate in fluid cultures. Study of the rate of budding in shallow broth cultures in Petri dishes showed that the addition of 20 mug/ml minocycline prolonged the lag phase by three hours. C. tropicalis was similarly inhibited and C. guilliermondii and C. parapsilosis to a lesser degree. Six other tetracyclines were tested and found to inhibit Candida only in very high concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212409"} {"pmid": "4212410", "title": "The effect of propranolol on left ventricular function in angina pectoris as measured by systolic time intervals.", "content": "The effect of propranolol on left ventricular function in angina pectoris as measured by systolic time intervals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212410"} {"pmid": "4212411", "title": "The effect of species-specific vocalization on the discharge of auditory cortical cells in the awake squirrel monkey. (Saimiri sciureus).", "content": "The effect of species-specific vocalization on the discharge of auditory cortical cells in the awake squirrel monkey. (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212411"} {"pmid": "4212412", "title": "The effect of sulphur dioxide on oxidising enzyme systems in plant tissues.", "content": "The effect of sulphur dioxide on oxidising enzyme systems in plant tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212412"} {"pmid": "4212414", "title": "The electrocardiogram of the Japanese (Coturnix coturnix japonica) and Bobwhite (Colinus virginianus) quail.", "content": "The electrocardiogram of the Japanese (Coturnix coturnix japonica) and Bobwhite (Colinus virginianus) quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212414"} {"pmid": "4212416", "title": "The function of the bladder neck in female goats.", "content": "The function of the bladder neck in female goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212416"} {"pmid": "4212415", "title": "The erythrocyte sedimentation rate in Rh-positive and Rh-negative donors.", "content": "The erythrocyte sedimentation rate in Rh-positive and Rh-negative donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212415"} {"pmid": "4212417", "title": "The genes for ribosomal ribonucleic acid.", "content": "The genes for ribosomal ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212417"} {"pmid": "4212418", "title": "The genetics of Penicillium chrysogenum.", "content": "The genetics of Penicillium chrysogenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212418"} {"pmid": "4212421", "title": "The hypocalcaemic effect of toluidine blue in sheep.", "content": "The hypocalcaemic effect of toluidine blue in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212421"} {"pmid": "4212420", "title": "The histochemical demonstration of hydrolytic enzymes in adjuvant-induced arthritis in rats.", "content": "The histochemical demonstration of hydrolytic enzymes in adjuvant-induced arthritis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212420"} {"pmid": "4212419", "title": "The goose that laid the golden bile: gallstone dissolution in man with chenodeoxycholic acid.", "content": "The goose that laid the golden bile: gallstone dissolution in man with chenodeoxycholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212419"} {"pmid": "4212422", "title": "The influence of pure polychlorinated biphenyl compounds on hepatic function in the rat.", "content": "The influence of pure polychlorinated biphenyl compounds on hepatic function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212422"} {"pmid": "4212413", "title": "The effect of synthetic thyrotropin releasing hormone (TRH) on cell proliferation of the anterior pituitary gland in organ culture. Preliminary report.", "content": "The effect of synthetic thyrotropin releasing hormone (TRH) on cell proliferation of the anterior pituitary gland in organ culture. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212413"} {"pmid": "4212423", "title": "The influence of stereochemical factors on drug disposition.", "content": "The influence of stereochemical factors on drug disposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212423"} {"pmid": "4212424", "title": "The inhibition by somatostatin of the thyrotropin response to thyrotropin-releasing hormone in normal subjects.", "content": "The inhibition by somatostatin of the thyrotropin response to thyrotropin-releasing hormone in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212424"} {"pmid": "4212425", "title": "The isolation and partial characterization of sulfonamide-resistant carbonic anhydrases from the liver of the male rat.", "content": "The isolation and partial characterization of sulfonamide-resistant carbonic anhydrases from the liver of the male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212425"} {"pmid": "4212427", "title": "The kinetics of substrate-competitive inhibition in ternary-complex mechanisms for enzyme reactions involving two substrates.", "content": "The kinetics of substrate-competitive inhibition in ternary-complex mechanisms for enzyme reactions involving two substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212427"} {"pmid": "4212426", "title": "The isolation of symbiotic streptococci.", "content": "The isolation of symbiotic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212426"} {"pmid": "4212428", "title": "The late effects of neonatal hyperthyroidism upon the hypothalamic-pituitary-thyroid axis in the rat.", "content": "The late effects of neonatal hyperthyroidism upon the hypothalamic-pituitary-thyroid axis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212428"} {"pmid": "4212429", "title": "The long term care of the patient suffering from cerebral palsy. 3.", "content": "The long term care of the patient suffering from cerebral palsy. 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212429"} {"pmid": "4212430", "title": "The long-term effects of marginal protein-energy deficiency.", "content": "The long-term effects of marginal protein-energy deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212430"} {"pmid": "4212431", "title": "The measurement of systolic time intervals by echocardiography.", "content": "The measurement of systolic time intervals by echocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212431"} {"pmid": "4212433", "title": "The multi-step cancer therapy concept with time-optimal post-therapy Theoretical aspects.", "content": "The multi-step cancer therapy concept with time-optimal post-therapy Theoretical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212433"} {"pmid": "4212432", "title": "The membrane association and dissociation of human glyceraldehyde-3-phosphate dehydrogenase under various conditions of hemolysis. Immunochemical evidence for the lack of binding under cellular conditions.", "content": "The membrane association and dissociation of human glyceraldehyde-3-phosphate dehydrogenase under various conditions of hemolysis. Immunochemical evidence for the lack of binding under cellular conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212432"} {"pmid": "4212434", "title": "The nature and time of occurrence of radiation-induced nondisjunction of the acrocentric X and fourth chromosomes in Drosophila melanogaster females.", "content": "The nature and time of occurrence of radiation-induced nondisjunction of the acrocentric X and fourth chromosomes in Drosophila melanogaster females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212434"} {"pmid": "4212435", "title": "The neurological mechanisms of pain. A review.", "content": "The neurological mechanisms of pain. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212435"} {"pmid": "4212436", "title": "The occurrence in sera with m-components of different proteins related to amyloid fibrils.", "content": "The occurrence in sera with m-components of different proteins related to amyloid fibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212436"} {"pmid": "4212438", "title": "The president's page: health care delivery.", "content": "The president's page: health care delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212438"} {"pmid": "4212437", "title": "The physiology of mould-yeast dimorphism in the genus Mycotypha (Mucorales).", "content": "The physiology of mould-yeast dimorphism in the genus Mycotypha (Mucorales).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212437"} {"pmid": "4212439", "title": "The problem of cultivation of Mycobacterium leprae. A review with criteria for evaluating recent experimental work.", "content": "The problem of cultivation of Mycobacterium leprae. A review with criteria for evaluating recent experimental work. Some criteria are presented to help evaluate papers appearing in the literature claiming successful cultivation of M. leprae either in the absence or in the presence of tissue-cultured cells. Recently, electron microscopic studies have definitely shown M. leprae to belong to the genus Mycobacterium and its division to occur through transverse section. A survey is given of the mycobacterial strains isolated in the last 10 years from leprosy lesions. These strains belong to taxonomically different species and cannot be considered to be M. leprae. No substantiated claim was made concerning the in vitro growth of M. leprae and the application of the tissue culture technique has been equally disappointing. The view is expressed that progress towards the in vitro cultivation of M. leprae can be made only as a result of increased knowledge about the intracellular environment and the metabolic activities of this organism, to be obtained by the application of modern biochemical and histochemical techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212439"} {"pmid": "4212440", "title": "The processing of edge information in visual areas of the cortex as evidenced by evoked potentials.", "content": "The processing of edge information in visual areas of the cortex as evidenced by evoked potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212440"} {"pmid": "4212441", "title": "The protection of mice by a specific anti-Erysipelothrix insidiosa-neuraminidase-antiserum against Erysipelothrix insidiosa infection.", "content": "The protection of mice by a specific anti-Erysipelothrix insidiosa-neuraminidase-antiserum against Erysipelothrix insidiosa infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212441"} {"pmid": "4212442", "title": "The purification and some properties of brewer's yeast apotransketolase.", "content": "The purification and some properties of brewer's yeast apotransketolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212442"} {"pmid": "4212443", "title": "The purification of the DNA polymerase from Micrococcus luteus.", "content": "The purification of the DNA polymerase from Micrococcus luteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212443"} {"pmid": "4212444", "title": "The red crowned mangabey, Cercocebus torquatus, in western Nigeria.", "content": "The red crowned mangabey, Cercocebus torquatus, in western Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212444"} {"pmid": "4212445", "title": "The rejection of malignant and non-malignant homografts: a new hypothesis.", "content": "The rejection of malignant and non-malignant homografts: a new hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212445"} {"pmid": "4212446", "title": "The relation between nutritional deprivation and immunity.", "content": "The relation between nutritional deprivation and immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212446"} {"pmid": "4212447", "title": "The response of the heterotopic pituitary to thyrotropin releasing hormone (TRH).", "content": "The response of the heterotopic pituitary to thyrotropin releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212447"} {"pmid": "4212448", "title": "The risks associated with treatment in the African diabetic.", "content": "The risks associated with treatment in the African diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212448"} {"pmid": "4212449", "title": "The role of bicarbonate in proximal tubular sodium chloride transport.", "content": "The role of bicarbonate in proximal tubular sodium chloride transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212449"} {"pmid": "4212451", "title": "The sensitivity of the Rh--anti-Rh system to ordered water of hydration.", "content": "The sensitivity of the Rh--anti-Rh system to ordered water of hydration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212451"} {"pmid": "4212452", "title": "The solution of the paradox of psychotherapy and its corollaries.", "content": "The solution of the paradox of psychotherapy and its corollaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212452"} {"pmid": "4212453", "title": "The specificity of anti-galactocerebroside antibody and its reaction with lysolecithin-solubilized myelin.", "content": "The specificity of anti-galactocerebroside antibody and its reaction with lysolecithin-solubilized myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212453"} {"pmid": "4212454", "title": "The synthesis and distribution of DNA in the macronucleus of Euplotes eurystomus.", "content": "The synthesis and distribution of DNA in the macronucleus of Euplotes eurystomus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212454"} {"pmid": "4212455", "title": "The synthesis of phospholipase C by Bacillus cereus. II. A screening method for mutants.", "content": "The synthesis of phospholipase C by Bacillus cereus. II. A screening method for mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212455"} {"pmid": "4212457", "title": "The treatment of unstable ankle fractures.", "content": "The treatment of unstable ankle fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212457"} {"pmid": "4212456", "title": "The transplacental passage of thyroxine and foetal thyroid function in the rat.", "content": "The transplacental passage of thyroxine and foetal thyroid function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212456"} {"pmid": "4212458", "title": "The use of an ultrasonic bath to disrupt cells suspended in volumes of less than 100 micro liters.", "content": "The use of an ultrasonic bath to disrupt cells suspended in volumes of less than 100 micro liters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212458"} {"pmid": "4212450", "title": "The role of the mental health practitioner in long-term medical treatment.", "content": "The role of the mental health practitioner in long-term medical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212450"} {"pmid": "4212459", "title": "The use of bovine carotid grafts for hemodialysis and hyperalimentation.", "content": "The use of bovine carotid grafts for hemodialysis and hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212459"} {"pmid": "4212460", "title": "The utilization of 2-ketogluconate by Hydrogenomonas eutropha H 16.", "content": "The utilization of 2-ketogluconate by Hydrogenomonas eutropha H 16.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212460"} {"pmid": "4212462", "title": "The vitamin A transporting system in porcine plasma.", "content": "The vitamin A transporting system in porcine plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212462"} {"pmid": "4212461", "title": "The vascular lesions of neurofibromatosis.", "content": "The vascular lesions of neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212461"} {"pmid": "4212463", "title": "The wheat embryo cell-free system.", "content": "The wheat embryo cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212463"} {"pmid": "4212464", "title": "The Law and force-feeding.", "content": "The Law and force-feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212464"} {"pmid": "4212465", "title": "The Sargenti revival.", "content": "The Sargenti revival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212465"} {"pmid": "4212467", "title": "Thiosulphate compleximetric determination of bismuth in some organic pharmaceutical chemicals.", "content": "Thiosulphate compleximetric determination of bismuth in some organic pharmaceutical chemicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212467"} {"pmid": "4212466", "title": "Theory for the sequence of human and rat enamel dissolution by acid and by EDTA: a correlated scanning and transmission electron microscope study.", "content": "Theory for the sequence of human and rat enamel dissolution by acid and by EDTA: a correlated scanning and transmission electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212466"} {"pmid": "4212468", "title": "Thrombocythemia and myocardial ischemia with normal coronary angiogram.", "content": "Thrombocythemia and myocardial ischemia with normal coronary angiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212468"} {"pmid": "4212469", "title": "Thymectomy and bursectomy in chickens with simultaneous experimental and spontaneous autoimmune disease.", "content": "Thymectomy and bursectomy in chickens with simultaneous experimental and spontaneous autoimmune disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212469"} {"pmid": "4212470", "title": "Thyrotropin-releasing hormone (TRH): distribution in hypothalamic and extrahypothalamic brain tissues of mammalian and submammalian chordates.", "content": "Thyrotropin-releasing hormone (TRH): distribution in hypothalamic and extrahypothalamic brain tissues of mammalian and submammalian chordates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212470"} {"pmid": "4212472", "title": "Topology of the caudal fat body of the tumor-w mutant of Drosophila melanogaster.", "content": "Topology of the caudal fat body of the tumor-w mutant of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212472"} {"pmid": "4212471", "title": "Tissue response to cryosurgery of oral cavity in rhesus monkeys.", "content": "Tissue response to cryosurgery of oral cavity in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212471"} {"pmid": "4212475", "title": "Toxicity of aerosol propellants in the respiratory and circulatory systems. IV. Cardiotoxicity in the monkey.", "content": "Toxicity of aerosol propellants in the respiratory and circulatory systems. IV. Cardiotoxicity in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212475"} {"pmid": "4212476", "title": "Toxicity of halogenated oxyquinolines in dogs. A clinical study. II. History, symptoms, laboratory findings, therapy, and follow-up.", "content": "Toxicity of halogenated oxyquinolines in dogs. A clinical study. II. History, symptoms, laboratory findings, therapy, and follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212476"} {"pmid": "4212477", "title": "Toxicologic studies of four fluorescent whitening agents.", "content": "Toxicologic studies of four fluorescent whitening agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212477"} {"pmid": "4212478", "title": "Transient diabetes insipidus in a newborn infant.", "content": "Transient diabetes insipidus in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212478"} {"pmid": "4212479", "title": "Transmission of parotin through the sacs of everted intestine and its demonstration in mesenteric perfusate.", "content": "Transmission of parotin through the sacs of everted intestine and its demonstration in mesenteric perfusate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212479"} {"pmid": "4212480", "title": "Transmission of Plasmodium fragile to Aotus trivirgatus monkeys.", "content": "Transmission of Plasmodium fragile to Aotus trivirgatus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212480"} {"pmid": "4212473", "title": "Total cerebral blood flow in the monkey measured by hydrogen clearance.", "content": "Total cerebral blood flow in the monkey measured by hydrogen clearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212473"} {"pmid": "4212481", "title": "Transpeptidases and D,D-carboxypeptidases in bacilli.", "content": "Transpeptidases and D,D-carboxypeptidases in bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212481"} {"pmid": "4212482", "title": "Transplantable immunoglobulin-secreting tumours in rats. IV. Sixty-three IgE-secreting immunocytoma tumours.", "content": "Transplantable immunoglobulin-secreting tumours in rats. IV. Sixty-three IgE-secreting immunocytoma tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212482"} {"pmid": "4212474", "title": "Total intravenous hyperalimentation in the management of cecal fistulas: Report of two cases.", "content": "Total intravenous hyperalimentation in the management of cecal fistulas: Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212474"} {"pmid": "4212484", "title": "Trisomy D in bone marrow cells in a patient with chronic myelogenous leukemia.", "content": "Trisomy D in bone marrow cells in a patient with chronic myelogenous leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212484"} {"pmid": "4212483", "title": "Triple tetracycline in lower respiratory tract infections.", "content": "Triple tetracycline in lower respiratory tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212483"} {"pmid": "4212485", "title": "Trisomy 18 mosaicism in two siblings.", "content": "Trisomy 18 mosaicism in two siblings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212485"} {"pmid": "4212486", "title": "Triterpenoid carotenoids and related lipids. The triterpenoid carotenes of Streptococcus faecium UNH 564P.", "content": "Triterpenoid carotenoids and related lipids. The triterpenoid carotenes of Streptococcus faecium UNH 564P. 1. The occurrence of a novel series of triterpenoid carotenes in Streptococcus faecium UNH 564P is reported. 2. This series, which comprises the C(30) analogues of phytoene, phytofluene, zeta-carotene, 7,8,11,12-tetrahydrolycopene and neurosporene, appears to be analogous to the C(40) Porter-Lincoln series and a pathway of triterpenoid carotene dehydrogenation is proposed to account for the formation of these compounds. 3. Two cis isomers of the C(30) analogue of neurosporene are described. 4. An appropriate system of nomenclature for these novel compounds is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212486"} {"pmid": "4212487", "title": "Triterpenoid carotenoids and related lipids. Triterpenoid monohydroxy- and monoglucosyloxy-carotenoids from Streptococcus faecium UNH 564P.", "content": "Triterpenoid carotenoids and related lipids. Triterpenoid monohydroxy- and monoglucosyloxy-carotenoids from Streptococcus faecium UNH 564P. 1. The characterization of two novel triterpenoid xanthophylls occurring in Streptococcus faecium UNH 564P is described. 2. Both are derived formally, and probably biosynthetically, from the C(30) analogue of neurosporene and have been identified as 4-hydroxy-4,4'-diaponeurosporene and its glucoside, 4-d-glucopyranosyloxy-4,4'-diaponeurosporene. 3. Problems associated with the use of specific glucosidases in defining the anomerism of carotenoid glucosides are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212487"} {"pmid": "4212488", "title": "Tryptic fragments of Fc from normal human IgG and their interaction with staphylococcal protein A.", "content": "Tryptic fragments of Fc from normal human IgG and their interaction with staphylococcal protein A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212488"} {"pmid": "4212489", "title": "Tuberculous perforation of the small intestine.", "content": "Tuberculous perforation of the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212489"} {"pmid": "4212490", "title": "Two methodological problems.", "content": "Two methodological problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212490"} {"pmid": "4212491", "title": "Two methods of extraction and partial purification of Drosophila melanogaster RNA polymerase.", "content": "Two methods of extraction and partial purification of Drosophila melanogaster RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212491"} {"pmid": "4212493", "title": "Two-dimensional polyacrylamide gel electrophoresis for separation of ribosomal proteins.", "content": "Two-dimensional polyacrylamide gel electrophoresis for separation of ribosomal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212493"} {"pmid": "4212492", "title": "Two types of molecular evolution. Evidence from studies of interspecific hybridization.", "content": "Two types of molecular evolution. Evidence from studies of interspecific hybridization. To assess the significance of macromolecular sequence differences among species, we compared the serum albumins of 81 pairs of vertebrate species capable of producing viable hybrids. Micro-complement fixation experiments showed that the average difference between the albumins within such pairs was only 3 immunological distance units for placental mammals (31 pairs), but 36 units for frogs (50 pairs). Albumin immunological distance is strongly correlated with other measures of genetic distance, including those made with DNA annealing techniques. It therefore seems likely that mammalian species pairs capable of hybridization are far more similar at the macromolecular sequence level than is the case for most hybridizable frogs. We think the most likely explanation for the marked molecular restriction on hybridization among mammals is that the ratio of regulatory evolution to protein evolution is higher for mammals than for frogs. Mammals may have experienced unusually rapid regulatory evolution; indeed, this could be the factor responsible for their unusually rapid anatomical evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212492"} {"pmid": "4212494", "title": "Two-step inhibition of Bacillus cereus penicillinase by dicloxacillin.", "content": "Two-step inhibition of Bacillus cereus penicillinase by dicloxacillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212494"} {"pmid": "4212495", "title": "Ultra-structure, in vitro cultivation and metabolism of cells isolated from arthritic human bone.", "content": "Ultra-structure, in vitro cultivation and metabolism of cells isolated from arthritic human bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212495"} {"pmid": "4212496", "title": "Ultrahistochemical demonstration of calcium ions by a freeze-substitution method.", "content": "Ultrahistochemical demonstration of calcium ions by a freeze-substitution method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212496"} {"pmid": "4212497", "title": "Ultrasonography of the chest wall.", "content": "Ultrasonography of the chest wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212497"} {"pmid": "4212499", "title": "Ultrastructural study of liver cell injury due to UTP deficiency.", "content": "Ultrastructural study of liver cell injury due to UTP deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212499"} {"pmid": "4212498", "title": "Ultrasound and scintigraphy in the differential diagnosis of obstructive jaundice.", "content": "Ultrasound and scintigraphy in the differential diagnosis of obstructive jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212498"} {"pmid": "4212500", "title": "Unusual metabolism of caffeine in the squirrel monkey.", "content": "Unusual metabolism of caffeine in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212500"} {"pmid": "4212501", "title": "Uptake and subcellular distribution of vitamin B12 in mouse L1210 leukemic lymphoblasts.", "content": "Uptake and subcellular distribution of vitamin B12 in mouse L1210 leukemic lymphoblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212501"} {"pmid": "4212502", "title": "Urban rodent-borne disease and rodent distribution in Israel and nighboring countries.", "content": "Urban rodent-borne disease and rodent distribution in Israel and nighboring countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212502"} {"pmid": "4212504", "title": "Use of microculture plates and the multiple automated sample harvester for in vitro microassay of bacterial toxins.", "content": "Use of microculture plates and the multiple automated sample harvester for in vitro microassay of bacterial toxins. An in vitro cytotoxicity microassay for the measurement of nanogram quantities of Pseudomonas aeruginosa exotoxin and Vibrio cholerae enterotoxin is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212504"} {"pmid": "4212503", "title": "Use of central and peripheral temperature measurements in care of the critically ill child.", "content": "Use of central and peripheral temperature measurements in care of the critically ill child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212503"} {"pmid": "4212505", "title": "Use of the single radial diffusion technique for influenza antibody surveys.", "content": "Use of the single radial diffusion technique for influenza antibody surveys. A survey of antibody to the influenza A/Hong Kong/1/68 (H3N2) and the variant A/England/42/72 (H3N2) was carried out by two methods, haemagglutination-inhibition (HI) and single radial diffusion (SRD). A comparison of the sensitivity of the two tests indicated that the proportion of sera that produced a zone of 2.5 mm or larger in the SRD tests was equivalent to the proportion that gave HI titres of 1: 40 or more. The test was carried out on serum samples collected from various regions of England. The results showed that approximately 70% had antibody to the A/HK/1/68 virus and only 35% had antibody to A/England/42/72. The SRD test was shown to have several practical advantages for seroepidemiological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212505"} {"pmid": "4212506", "title": "Use of trace elements in intravenous hyperalimentation solutions.", "content": "Use of trace elements in intravenous hyperalimentation solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212506"} {"pmid": "4212507", "title": "Use of 8-anilino-1-naphthalenesulfonic acid in radioimmunoassay of triiodothyronine.", "content": "Use of 8-anilino-1-naphthalenesulfonic acid in radioimmunoassay of triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212507"} {"pmid": "4212508", "title": "Uses of prolactin- and growth hormone-producing rat pituitary tumor cells in culture.", "content": "Uses of prolactin- and growth hormone-producing rat pituitary tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212508"} {"pmid": "4212509", "title": "UDP-glucuronyltransferase activity towards oestriol in fresh and cultured foetal tissues from man and other species.", "content": "UDP-glucuronyltransferase activity towards oestriol in fresh and cultured foetal tissues from man and other species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212509"} {"pmid": "4212510", "title": "UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene.", "content": "UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212510"} {"pmid": "4212511", "title": "Vaccination against Marek's disease: immunizing effect of purified turkey herpes virus and cellular membranes from infected cells.", "content": "Vaccination against Marek's disease: immunizing effect of purified turkey herpes virus and cellular membranes from infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212511"} {"pmid": "4212513", "title": "Vesicoureteral reflux in the primate.", "content": "Vesicoureteral reflux in the primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212513"} {"pmid": "4212512", "title": "Vertebrobasilar arterial insufficiency with dementia. Controlled trials of treatment with betahistine hydrochloride.", "content": "Vertebrobasilar arterial insufficiency with dementia. Controlled trials of treatment with betahistine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212512"} {"pmid": "4212514", "title": "Viral hepatitis and autoimmune liver diseases.", "content": "Viral hepatitis and autoimmune liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212514"} {"pmid": "4212515", "title": "Viral vaccines: various cell substrates and long-term prospective studies.", "content": "Viral vaccines: various cell substrates and long-term prospective studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212515"} {"pmid": "4212516", "title": "Von Willebrand's disease in Italy. A study of 13 families from a small area in the province of Vicenza.", "content": "Von Willebrand's disease in Italy. A study of 13 families from a small area in the province of Vicenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212516"} {"pmid": "4212517", "title": "31P-NMR studies of tRNA.", "content": "31P-NMR studies of tRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212517"} {"pmid": "4212518", "title": "5'-Nucleotidase and an acid phosphatase of spinal cord. Comparative histochemistry and specificity of the enzymes in mouse and cat spinal cords. Cytologic localization in mouse substantia gelatinosa.", "content": "5'-Nucleotidase and an acid phosphatase of spinal cord. Comparative histochemistry and specificity of the enzymes in mouse and cat spinal cords. Cytologic localization in mouse substantia gelatinosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212518"} {"pmid": "4212521", "title": "Panel discussion: practical importance of generic equivalence.", "content": "Panel discussion: practical importance of generic equivalence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212521"} {"pmid": "4212522", "title": "'A matter of routine'; relationships between temporary disablement patterns of stress and type of care.", "content": "'A matter of routine'; relationships between temporary disablement patterns of stress and type of care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212522"} {"pmid": "4212523", "title": "\"The classification of viruses; why, when, and how\".", "content": "\"The classification of viruses; why, when, and how\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212523"} {"pmid": "4212882", "title": "A case of neurilemmoma in the mandible.", "content": "A case of neurilemmoma in the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212882"} {"pmid": "4212883", "title": "A comparison of cortical functions in man and the other primates.", "content": "A comparison of cortical functions in man and the other primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212883"} {"pmid": "4212884", "title": "A double-blind crossover trial of disodium cromoglycate in asthmatic patients living under environmental control.", "content": "A double-blind crossover trial of disodium cromoglycate in asthmatic patients living under environmental control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212884"} {"pmid": "4212886", "title": "A fragment from the constant portion of IgG obtained by peptic digestion at high temperatures.", "content": "A fragment from the constant portion of IgG obtained by peptic digestion at high temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212886"} {"pmid": "4212885", "title": "A fine structural study on the extracellular activity of alkaline phosphatase and its role in calcification.", "content": "A fine structural study on the extracellular activity of alkaline phosphatase and its role in calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212885"} {"pmid": "4212887", "title": "A hazy ('bull's eye') plaque variant of bovine viral diarrhea virus.", "content": "A hazy ('bull's eye') plaque variant of bovine viral diarrhea virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212887"} {"pmid": "4212888", "title": "A hominid mandible from East Rudolf, Kenya.", "content": "A hominid mandible from East Rudolf, Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212888"} {"pmid": "4212889", "title": "A method for alpha-L-iduronidase assay.", "content": "A method for alpha-L-iduronidase assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212889"} {"pmid": "4212890", "title": "A new method for measuring the stress effects in minor oral surgery.", "content": "A new method for measuring the stress effects in minor oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212890"} {"pmid": "4212893", "title": "A precursor of the neck appendage protein of B. subtilis phage phi 29.", "content": "A precursor of the neck appendage protein of B. subtilis phage phi 29.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212893"} {"pmid": "4212892", "title": "A pleiotropic mutation affecting expression of polar development events in Caulobacter crescentus.", "content": "A pleiotropic mutation affecting expression of polar development events in Caulobacter crescentus. A developmental mutant of C. crescentus with altered polar surface structures has been isolated. The mutant lacks a flagellum and pili, and may have an abnormal DNA phage receptor site. A revertant regains the normal structures simultaneously. This point mutation allows normal flagellin synthesis, stalk formation, equatorial cell division, and rate of growth. The mutant phenotype indicates that the assembly of the polar surface structures is coordinately regulated and independent of mechanisms regulating cell polarity and division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212892"} {"pmid": "4212894", "title": "A pteridine adsorbent for affinity chromatography.", "content": "A pteridine adsorbent for affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212894"} {"pmid": "4212895", "title": "A quantitative method for analysing competition where individuals cannot be identified.", "content": "A quantitative method for analysing competition where individuals cannot be identified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212895"} {"pmid": "4212896", "title": "A rapid method for the separation of guinea pig IgGl and IgG2.", "content": "A rapid method for the separation of guinea pig IgGl and IgG2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212896"} {"pmid": "4212891", "title": "A note on the adjustment of rates.", "content": "A note on the adjustment of rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212891"} {"pmid": "4212897", "title": "A rapid procedure for the radioimmunoassay of rat growth hormone.", "content": "A rapid procedure for the radioimmunoassay of rat growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212897"} {"pmid": "4212898", "title": "A reinterpretation of research on aggression.", "content": "A reinterpretation of research on aggression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212898"} {"pmid": "4212901", "title": "A sporulation medium for Bacillus anthracis.", "content": "A sporulation medium for Bacillus anthracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212901"} {"pmid": "4212902", "title": "A stochastic locomotor control model for the goldfish (Carassius auratus).", "content": "A stochastic locomotor control model for the goldfish (Carassius auratus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212902"} {"pmid": "4212903", "title": "A study of the ultrastructure of human basophil leukocytes.", "content": "A study of the ultrastructure of human basophil leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212903"} {"pmid": "4212905", "title": "Abdominal wound infections and plastic wound guards.", "content": "Abdominal wound infections and plastic wound guards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212905"} {"pmid": "4212906", "title": "Abortion and menstrual extraction for the ambulatory patient.", "content": "Abortion and menstrual extraction for the ambulatory patient. Complications attending menstrual regulation, office suction and curettage abortion, and ambulatory hospital suction and curettage abortion are discussed and minimum criteria for outpatient abortion are sought. Guidelines established by the American College of Obstetricians and Gynecologists for the performance of abortion are reiterated. Uterine perforation, pelvic infections, hemorrhage, and incomplete evacuation are complications which should not exceed usual hospital rates when abortion is performed in an office. The possibilities that dilatation of the cervix in abortion may result in an increased risk of future stillbirth deliveries and premature delivery, that secondary infertility can result from subclinical salpingitis or the development of intrauterine synechia, and that an increased risk of ectopic pregnancy may result from abortion are long-term complications that must be considered. Standards, preoperative procedures, equipment and operative technique, and postoperative procedures and considerations in menstrual regulation are presented. The usual procedures for office and hospital suction curettage abortion are presented and discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212906"} {"pmid": "4212907", "title": "Absence of disulfide bridges between heavy and light chains in IgA from chicken bile.", "content": "Absence of disulfide bridges between heavy and light chains in IgA from chicken bile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212907"} {"pmid": "4212908", "title": "Accumulation of tritiated thyrotropin releasing hormone in different organs, especially in the thyroid.", "content": "Accumulation of tritiated thyrotropin releasing hormone in different organs, especially in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212908"} {"pmid": "4212909", "title": "Activation by ferrous ions of an alpha-mannosidase in rat testis and liver.", "content": "Activation by ferrous ions of an alpha-mannosidase in rat testis and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212909"} {"pmid": "4212911", "title": "Activity and sexual behavior of neurological mutants in Drosophila melanogaster.", "content": "Activity and sexual behavior of neurological mutants in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212911"} {"pmid": "4212910", "title": "Active avoidance and discrimination learning in rats with protein or calorie deficit and centrophenoxine or palmitoyl ethanolamide treatment in early postnatal life.", "content": "Active avoidance and discrimination learning in rats with protein or calorie deficit and centrophenoxine or palmitoyl ethanolamide treatment in early postnatal life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212910"} {"pmid": "4212899", "title": "A salmonellosis outbreak in New York City attributed to a catering establishment.", "content": "A salmonellosis outbreak in New York City attributed to a catering establishment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212899"} {"pmid": "4212904", "title": "A technique for standardizing the jet injector and Mantoux tuberculin skin tests.", "content": "A technique for standardizing the jet injector and Mantoux tuberculin skin tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212904"} {"pmid": "4212912", "title": "Acute myeloblastic leukemia after cure of ovarian cancer.", "content": "Acute myeloblastic leukemia after cure of ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212912"} {"pmid": "4212913", "title": "Acute myeloproliferative disorder following long-term chlorambucil therapy.", "content": "Acute myeloproliferative disorder following long-term chlorambucil therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212913"} {"pmid": "4212914", "title": "Adreno-leukodystrophy (sex-linked Schilder's disease). A pathogenetic hypothesis based on ultrastructural lesions in adrenal cortex, peripheral nerve and testis.", "content": "Adreno-leukodystrophy (sex-linked Schilder's disease). A pathogenetic hypothesis based on ultrastructural lesions in adrenal cortex, peripheral nerve and testis. Striated adrenal cells in the zona reticularis and inner fasciculata apparently constitute the initial adrenolytic lesion in patients with adreno-leukodystrophy (ALD). Cytoplasmic ballooning and macrovacuolization develop after the striations, and probably represent exaggerated responses to adrenocorticotropin (ACTH). Intracytoplasmic lamellae and lamellar-lipid profiles, containing a free 3beta-hydroxysterol, are the ultrastructural correlates of the striations seen with the light microscope. The ultrastructural demonstration of intracytoplasmic lamellae and lamellar-lipid profiles in adrenal striated cells, testicular interstitial cells, Schwann cells and brain macrophages from patients with ALD provides further morphologic evidence for a systemic metabolic defect common to the nervous and endocrine systems. In our experience, adrenal biopsy has proven to be the most effective procedure for the diagnosis of adreno-leukodystrophy. An hypothesis proposing a membrane abnormality affecting its stability and turnover might explain the concomitant destruction of adrenal cortex and brain in these patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212914"} {"pmid": "4212916", "title": "Albumin, immunoglobulin A and G concentrations in sputum during and after status asthmaticus.", "content": "Albumin, immunoglobulin A and G concentrations in sputum during and after status asthmaticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212916"} {"pmid": "4212915", "title": "Airborne infection.", "content": "Airborne infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212915"} {"pmid": "4212917", "title": "Aldosterone secretion in infantile malnutrition.", "content": "Aldosterone secretion in infantile malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212917"} {"pmid": "4212918", "title": "Aldosterone-induced protein in toad urinary bladder.", "content": "Aldosterone-induced protein in toad urinary bladder. Simultaneous electrophysiological and biochemical experiments demonstrated a specific aldosterone-induced protein in paired urinary hemibladders isolated from the toad Bufo marinus. Whenever aldosterone stinlmulated short-circuit current, aldosterone specifically increased [(35)S] methionine incorporation into a low-molecular-weight protein (about 12,000). Comparative studies with dexamethasone and insulin and inhibitory studies with spironolactone and actinomycin D suggest mineralocorticoid specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212918"} {"pmid": "4212919", "title": "Allograft tolerance in the absence of circulating antibodies.", "content": "Allograft tolerance in the absence of circulating antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212919"} {"pmid": "4212920", "title": "Alpha 1-antitrypsin in septic infections during infancy.", "content": "Alpha 1-antitrypsin in septic infections during infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212920"} {"pmid": "4212921", "title": "Alpha1 antitrypsin deficiency and liver disease in childhood: genetic, immunochemical, histological, and ultrastructural diagnosis.", "content": "Alpha1 antitrypsin deficiency and liver disease in childhood: genetic, immunochemical, histological, and ultrastructural diagnosis. alpha(1) Antitrypsin deficiency is a significant factor in the pathogenesis of neonatal cholestasis and progressive juvenile cirrhosis. The diagnosis may be suggested by the liver biopsy appearances and confirmed by immunochemical analysis of the serum. Genetic counselling of affected families is of importance, as medical treatment is ineffective at the present time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212921"} {"pmid": "4212922", "title": "Alpha1-antitrypsin and its deficiency.", "content": "Alpha1-antitrypsin and its deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212922"} {"pmid": "4212923", "title": "Alteration of antigenic components of rat parotid gland following denervation.", "content": "Alteration of antigenic components of rat parotid gland following denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212923"} {"pmid": "4212925", "title": "Alteration of nociception by stimulation of cerebellar structures in the monkey.", "content": "Alteration of nociception by stimulation of cerebellar structures in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212925"} {"pmid": "4212924", "title": "Alteration of epididymal function and its relation to maturation of spermatozoa.", "content": "Alteration of epididymal function and its relation to maturation of spermatozoa. Alteration of epididymal function and its relation to maturation of spermatozoa was studied in 54 adult male albino rats. Levels of free and bound sialic acid in the spermatozoa and luminal contents of the epididymis and vas deferens were determined. A group of 10 received rabbit antiserum to ovine luteinizing hormone (LHAS) sc .2 ml/day for 5 days. 2 groups of 8 animals each received 2.5 mg cyproterone acetate twice daily for either 15 or 30 days. 16 animals served as intact controls and 12 animals served as castrate controls. Epididymis and vas deferens sperm counts were not affected by LHAS for 5 days or by cyproterone acetate for 15 days; however, sperm counts were decreased in the corpus (p less than .02), cauda (p less than .05), epididymidis and vas deferens (p less than .01) when rats were treated with cyproterone acetate for 30 days. Castration resulted in a marked reduction in all regions within 5 days. In the intact rats spermatozoa sialic acid decreased in the cauda epididymidis (p less than .01) and increased in the vas deferens (p less than .001). Sialic acid concentration was similar in those treated with either LHAS or cyproterone acetate for 30 days. Bound sialic acid in the epididymal fluid increased (p less than .02) to a maximum in the corpus and cauda and decreased in the vas deferens (p less than .05). LHAS or cyproterone acetate caused a reduction in bound sialic acid in the fluid of the epididymis and vas deferens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212924"} {"pmid": "4212926", "title": "Alterations in circulating thyroid hormones and thyrotropin in hepatic cirrhosis: evidence for euthyroidism despite subnormal serum triiodothyronine.", "content": "Alterations in circulating thyroid hormones and thyrotropin in hepatic cirrhosis: evidence for euthyroidism despite subnormal serum triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212926"} {"pmid": "4212927", "title": "Amino acid sequence studies of human IgA myeloma proteins.", "content": "Amino acid sequence studies of human IgA myeloma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212927"} {"pmid": "4212929", "title": "An experimental study on the effect of local hemostatics on bone healing in rabbits.", "content": "An experimental study on the effect of local hemostatics on bone healing in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212929"} {"pmid": "4212931", "title": "An idiotypic cross-reaction between two streptococcal antibodies from an individual rabbit.", "content": "An idiotypic cross-reaction between two streptococcal antibodies from an individual rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212931"} {"pmid": "4212932", "title": "An immunochemical characterization of the phytochrome destruction reaction.", "content": "An immunochemical characterization of the phytochrome destruction reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212932"} {"pmid": "4212933", "title": "An improved method for liquid scintillation counting of 59Fe in ferrokinetic studies.", "content": "An improved method for liquid scintillation counting of 59Fe in ferrokinetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212933"} {"pmid": "4212934", "title": "An in vitro system for studying the kinetics of interchain disulfide bond formation in immunoglobulin G.", "content": "An in vitro system for studying the kinetics of interchain disulfide bond formation in immunoglobulin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212934"} {"pmid": "4212928", "title": "An assessment of provider behavior in shared professional facilities.", "content": "An assessment of provider behavior in shared professional facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212928"} {"pmid": "4212937", "title": "An omega protein from Drosophila melanogaster.", "content": "An omega protein from Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212937"} {"pmid": "4212939", "title": "An A-V shunt for long-term hyperalimentation in azotaemic patients.", "content": "An A-V shunt for long-term hyperalimentation in azotaemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212939"} {"pmid": "4212940", "title": "Analgesics. 2. Selected 5-substituted 5-(1-phenylethyl)barbituric acids.", "content": "Analgesics. 2. Selected 5-substituted 5-(1-phenylethyl)barbituric acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212940"} {"pmid": "4212941", "title": "Analysis of mathematical models of the effect of pH on fermentation processes and their use for calculating optimal fermentation conditions.", "content": "Analysis of mathematical models of the effect of pH on fermentation processes and their use for calculating optimal fermentation conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212941"} {"pmid": "4212942", "title": "Antagonism of prostaglandins induced uterine contraction by cyproheptadine hydrochloride.", "content": "Antagonism of prostaglandins induced uterine contraction by cyproheptadine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212942"} {"pmid": "4212943", "title": "Anti-histone KSAchicken antibody from guinea pig.", "content": "Anti-histone KSAchicken antibody from guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212943"} {"pmid": "4212935", "title": "An inexpensive methodology for immunization surveys.", "content": "An inexpensive methodology for immunization surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212935"} {"pmid": "4212944", "title": "Antibacterial action of the essential oils of some Australian Myrtaceae with special references to the activity of chromatographic fractions of oil of Eucalyptus citriodora.", "content": "Antibacterial action of the essential oils of some Australian Myrtaceae with special references to the activity of chromatographic fractions of oil of Eucalyptus citriodora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212944"} {"pmid": "4212945", "title": "Antibiotics, antiseptics and tubercle bacilli.", "content": "Antibiotics, antiseptics and tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212945"} {"pmid": "4212946", "title": "Antibody activation of mutant human fructosediphosphate aldolase B in liver extracts of patients with hereditary fructose intolerance.", "content": "Antibody activation of mutant human fructosediphosphate aldolase B in liver extracts of patients with hereditary fructose intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212946"} {"pmid": "4212947", "title": "Antibody affinity. VI. Synthesis of bivalent lactosyl haptens and their interaction with anti-lactosyl antibodies.", "content": "Antibody affinity. VI. Synthesis of bivalent lactosyl haptens and their interaction with anti-lactosyl antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212947"} {"pmid": "4212948", "title": "Anticomplementary sera in cutaneous vasculitis.", "content": "Anticomplementary sera in cutaneous vasculitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212948"} {"pmid": "4212949", "title": "Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures.", "content": "Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212949"} {"pmid": "4212950", "title": "Antisera produced to purified extracellular pectolytic enzymes from Sclerotinia fructigena.", "content": "Antisera produced to purified extracellular pectolytic enzymes from Sclerotinia fructigena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212950"} {"pmid": "4212936", "title": "An investigation of Takahashi's antitubercle phosphatide kaolin agglutination test (KAT) in leprosy.", "content": "An investigation of Takahashi's antitubercle phosphatide kaolin agglutination test (KAT) in leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212936"} {"pmid": "4212952", "title": "Application of the continuous maximum principle to fermentation processes.", "content": "Application of the continuous maximum principle to fermentation processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212952"} {"pmid": "4212954", "title": "Arteriovenous fistula for self-treatment of hemophilia.", "content": "Arteriovenous fistula for self-treatment of hemophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212954"} {"pmid": "4212953", "title": "Arterial lesions associated with neurofibromatosis.", "content": "Arterial lesions associated with neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212953"} {"pmid": "4212955", "title": "Assay of rifampicin in serum.", "content": "Assay of rifampicin in serum. Two methods for the assay of rifampicin in serum are described. The first is a conventional plate diffusion method, measuring concentrations down to 0.02 mug/ml, and the second a chemical extraction followed by measurement of the inhibition of uptake of (14)C-uridine by Staphylococcus aureus, which estimates in the range of 0.02 to 0.001 mug/ml. The methods were used to measure serum concentrations in man following doses of about 1050 mg and 75 mg rifampicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212955"} {"pmid": "4212957", "title": "Association of type II congenital dyserythropoietic anaemia and von Willebrand's disease.", "content": "Association of type II congenital dyserythropoietic anaemia and von Willebrand's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212957"} {"pmid": "4212956", "title": "Assembly and secretion of immunoglobulin A.", "content": "Assembly and secretion of immunoglobulin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212956"} {"pmid": "4212959", "title": "Autoconjugates in Tetrahymena.", "content": "Autoconjugates in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212959"} {"pmid": "4212960", "title": "Autodilution of fungal spore suspensions for viable counting.", "content": "Autodilution of fungal spore suspensions for viable counting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212960"} {"pmid": "4212961", "title": "Automated determination of the IgG and IgM fractions of Rhesus antibodies.", "content": "Automated determination of the IgG and IgM fractions of Rhesus antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212961"} {"pmid": "4212962", "title": "Autonomous rDNA molecules containing single copies of the ribosomal RNA genes in the macronucleus of Tetrahymena pyriformis.", "content": "Autonomous rDNA molecules containing single copies of the ribosomal RNA genes in the macronucleus of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212962"} {"pmid": "4212963", "title": "B cell-derived immunoglobulin on activated mouse T lymphocytes.", "content": "B cell-derived immunoglobulin on activated mouse T lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212963"} {"pmid": "4212964", "title": "Background activity in single cells of monkey visual cortex during visual tracking.", "content": "Background activity in single cells of monkey visual cortex during visual tracking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212964"} {"pmid": "4212965", "title": "Bacteremic Pseudomonas pneumonia.", "content": "Bacteremic Pseudomonas pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212965"} {"pmid": "4212951", "title": "Apparent changes in cancer mortality, 1968. A study of the effects of the introduction of the Eighth Revision International Classification of Diseases.", "content": "Apparent changes in cancer mortality, 1968. A study of the effects of the introduction of the Eighth Revision International Classification of Diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212951"} {"pmid": "4212966", "title": "Bacteriological findings in perinatal pneumonia.", "content": "Bacteriological findings in perinatal pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212966"} {"pmid": "4212967", "title": "Baker's yeast cytidine deaminase: substrate and inhibitor specificity, and a hypothesis on metabolic and regulatory significance.", "content": "Baker's yeast cytidine deaminase: substrate and inhibitor specificity, and a hypothesis on metabolic and regulatory significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212967"} {"pmid": "4212968", "title": "Beta-glucuronidase in the streptococcal groups B and D.", "content": "Beta-glucuronidase in the streptococcal groups B and D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212968"} {"pmid": "4212969", "title": "Bilateral recurrent pneumothoraces: a rare complication of miliary tuberculosis.", "content": "Bilateral recurrent pneumothoraces: a rare complication of miliary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212969"} {"pmid": "4212970", "title": "Biochemical changes in the artery wall during genesis and regression of atheromatous lesions.", "content": "Biochemical changes in the artery wall during genesis and regression of atheromatous lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212970"} {"pmid": "4212972", "title": "Blood group investigations among the gypsy population of Hungary. I. Examination of ABO, MN and Rh blood groups.", "content": "Blood group investigations among the gypsy population of Hungary. I. Examination of ABO, MN and Rh blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212972"} {"pmid": "4212971", "title": "Biphasic stimulo-inhibitory effect of flavonoids on cell proliferation in vitro.", "content": "Biphasic stimulo-inhibitory effect of flavonoids on cell proliferation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212971"} {"pmid": "4212974", "title": "Bovine adrenal medullary dopamine-beta-hydroxylase: studies on the structure.", "content": "Bovine adrenal medullary dopamine-beta-hydroxylase: studies on the structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212974"} {"pmid": "4212975", "title": "Bronchial lymphoid tissue.", "content": "Bronchial lymphoid tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212975"} {"pmid": "4212976", "title": "Bursal and postbursal cells in chicken. Occurrence of postbursal cells in bone marrow, thymus and spleen.", "content": "Bursal and postbursal cells in chicken. Occurrence of postbursal cells in bone marrow, thymus and spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212976"} {"pmid": "4212977", "title": "Cannabis: review of behavioral effects in animals.", "content": "Cannabis: review of behavioral effects in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212977"} {"pmid": "4212978", "title": "Capillaria hepatica: granuloma formation to eggs. II. Peripheral immunological responses.", "content": "Capillaria hepatica: granuloma formation to eggs. II. Peripheral immunological responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212978"} {"pmid": "4212979", "title": "Carbonic anhydrase isoenzyme B in erythrocytes of subjects with thyroid disorders.", "content": "Carbonic anhydrase isoenzyme B in erythrocytes of subjects with thyroid disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212979"} {"pmid": "4212980", "title": "Carbonic anhydrase isoenzymes in nine troops of Kenya baboons, Papio cynocephalus (Linnaeus 1766).", "content": "Carbonic anhydrase isoenzymes in nine troops of Kenya baboons, Papio cynocephalus (Linnaeus 1766).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212980"} {"pmid": "4212981", "title": "Carriage of potentially pathogenic bacteria in the hair.", "content": "Carriage of potentially pathogenic bacteria in the hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212981"} {"pmid": "4212973", "title": "Blood-group U antigen on Rhnull leukocytes.", "content": "Blood-group U antigen on Rhnull leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212973"} {"pmid": "4212982", "title": "Cause and identification of taste and odour compounds in water.", "content": "Cause and identification of taste and odour compounds in water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212982"} {"pmid": "4212983", "title": "Cell growth cycle and expression of histocompatibility antigens on cultured human lymphoid cells.", "content": "Cell growth cycle and expression of histocompatibility antigens on cultured human lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212983"} {"pmid": "4212984", "title": "Changes in metabolism of undamaged sections of myocardium following infarction.", "content": "Changes in metabolism of undamaged sections of myocardium following infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212984"} {"pmid": "4212985", "title": "Changes in the autoimmunologic reactivity of Wistar rats receiving Freund's complete adjuvant.", "content": "Changes in the autoimmunologic reactivity of Wistar rats receiving Freund's complete adjuvant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212985"} {"pmid": "4212987", "title": "Characteristics of unit responses in superior colliculus of the Cebus monkey.", "content": "Characteristics of unit responses in superior colliculus of the Cebus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212987"} {"pmid": "4212986", "title": "Characteristics of acid phosphatase in Porcellio laevis latreille (Porcellionidae, Isopoda).", "content": "Characteristics of acid phosphatase in Porcellio laevis latreille (Porcellionidae, Isopoda).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212986"} {"pmid": "4212988", "title": "Characterization of degradation products of the cell wall released during growth and sporulation of Bacillus megaterium.", "content": "Characterization of degradation products of the cell wall released during growth and sporulation of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212988"} {"pmid": "4212989", "title": "Chemical and biological basis of adjuvants.", "content": "Chemical and biological basis of adjuvants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212989"} {"pmid": "4212990", "title": "Chemical, serological and biological properties of a serotype-specific polysaccharide antigen in Leptospira.", "content": "Chemical, serological and biological properties of a serotype-specific polysaccharide antigen in Leptospira.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212990"} {"pmid": "4212991", "title": "Chitinase activity during Drosophila development.", "content": "Chitinase activity during Drosophila development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212991"} {"pmid": "4212992", "title": "Chromosome abnormalities in rabbit preimplantation blastocysts induced by superovulation.", "content": "Chromosome abnormalities in rabbit preimplantation blastocysts induced by superovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212992"} {"pmid": "4212994", "title": "Chronic membranous glomerulonephritis caused by hepatitis B antigen-antibody immune complexes.", "content": "Chronic membranous glomerulonephritis caused by hepatitis B antigen-antibody immune complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212994"} {"pmid": "4212993", "title": "Chronic liver disease and hepatitis-B antigen: a prospective study.", "content": "Chronic liver disease and hepatitis-B antigen: a prospective study. A long-term follow-up of 45 patients with chronic hepatitis and 41 with cirrhosis is reported. Hepatitis-B antigen (HBAg) was present in 19 (42%) of the chronic hepatitis patients and in 20 (49%) of those with cirrhosis. The clinical course and biochemical and histological findings in the HBAg-positive and the HBAg-negative cases were similar, suggesting that HBAg-positive chronic liver disease is not a distinct clinical entity. The presence of antigen and autoantibodies was not found to be mutually exclusive. In HBAg-positive cases antigen tended to persist for months and years. When no irreversible lesions exist disappearance of the antigen may be a sign that the liver disease will resolve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212993"} {"pmid": "4212995", "title": "Cicatricial pemphigoid. Immunofluorescent studies.", "content": "Cicatricial pemphigoid. Immunofluorescent studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212995"} {"pmid": "4212996", "title": "Clinical and laboratory studies with tobramycin.", "content": "Clinical and laboratory studies with tobramycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212996"} {"pmid": "4212997", "title": "Clinical effects and uses of hypothalamic releasing and inhibiting factors.", "content": "Clinical effects and uses of hypothalamic releasing and inhibiting factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212997"} {"pmid": "4212998", "title": "Clinical manifestations of coxsackievirus infections in children.", "content": "Clinical manifestations of coxsackievirus infections in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212998"} {"pmid": "4212999", "title": "Clonazepam in the treatment of epilepsy.", "content": "Clonazepam in the treatment of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4212999"} {"pmid": "4213000", "title": "Coexistent respiratory allergy and cystic fibrosis.", "content": "Coexistent respiratory allergy and cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213000"} {"pmid": "4213001", "title": "Common parameters in genetic athymia and senescence.", "content": "Common parameters in genetic athymia and senescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213001"} {"pmid": "4213002", "title": "Comparative structure, morphogenesis and biological characteristics of the respiratory syncytial (RS) virus and the pneumonia virus of mice (PVM).", "content": "Comparative structure, morphogenesis and biological characteristics of the respiratory syncytial (RS) virus and the pneumonia virus of mice (PVM).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213002"} {"pmid": "4213004", "title": "Comparative value of various methods for the preparation of complement-fixing rubella antigen.", "content": "Comparative value of various methods for the preparation of complement-fixing rubella antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213004"} {"pmid": "4213003", "title": "Comparative study of platelet aggregation in various species.", "content": "Comparative study of platelet aggregation in various species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213003"} {"pmid": "4213005", "title": "Comparison between determination of free thyroxine index and effective thyroxine ratio in human serum.", "content": "Comparison between determination of free thyroxine index and effective thyroxine ratio in human serum. Four thyroid function indices were determined in the sera of 181 patients: total thyroxine (T-4), the triiodothyronine resin uptake (T-3 B.C.-index), the free thyroxine (T-4) index, and the effective thyroxine ratio (E.T.R.).A statistically significant correlation between the free T-4 index and E.T.R. could be established though this correlation seemed to be worse than could be expected from the literature. Two sets of correlation coefficients were shown: one obtained with the ordinarily used Pearson or product-moment correlation and one with the Spearman rank correlation. Because the assumptions and requirements for the proper use of the product-moment correlation statistics, such as a normal distribution of both variables, are seldom met, expecially not if a selected number of controls and patients is used for the correlation, it is advisable to use some kind of rank correlation statistics instead.The advantages and disadvantages of the E.T.R. and free T-4 index determination are described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213005"} {"pmid": "4213007", "title": "Comparison of the lodoamino acid distribution in thyroglobulins obtained from various animal species.", "content": "Comparison of the lodoamino acid distribution in thyroglobulins obtained from various animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213007"} {"pmid": "4213006", "title": "Comparison of different methods for determination of glomerular filtration rate in renal disease.", "content": "Comparison of different methods for determination of glomerular filtration rate in renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213006"} {"pmid": "4213008", "title": "Comparison of transportation media for the culturing of N. gonorrhoeae.", "content": "Comparison of transportation media for the culturing of N. gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213008"} {"pmid": "4213009", "title": "Consumer price differentials between generic and brand name prescriptions.", "content": "Consumer price differentials between generic and brand name prescriptions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213009"} {"pmid": "4213010", "title": "Contractile responses and 45Ca movements in monkey ileal smooth muscle.", "content": "Contractile responses and 45Ca movements in monkey ileal smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213010"} {"pmid": "4213011", "title": "Contribution to the study of the genesis and regulation of characteristic quantities of the quantitative ballistocardiogram.", "content": "Contribution to the study of the genesis and regulation of characteristic quantities of the quantitative ballistocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213011"} {"pmid": "4213012", "title": "Contributions to the optimal use of human blood. IV. Quantitative analysis of the immunoglobulin isolation.", "content": "Contributions to the optimal use of human blood. IV. Quantitative analysis of the immunoglobulin isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213012"} {"pmid": "4213014", "title": "Correlated responses of different scute genotypes to long-term selection for increased abdominal bristle number in Drosophila melanogaster.", "content": "Correlated responses of different scute genotypes to long-term selection for increased abdominal bristle number in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213014"} {"pmid": "4213013", "title": "Contributions to the optimal use of human blood. V. A method to increase the yield of anti-D immunoglobulin by processing Cohn's fraction III.", "content": "Contributions to the optimal use of human blood. V. A method to increase the yield of anti-D immunoglobulin by processing Cohn's fraction III.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213013"} {"pmid": "4213015", "title": "Corynebacterium parvum as a therapeutic antitumor agent in mice. I. Systemic effects from intravenous injection.", "content": "Corynebacterium parvum as a therapeutic antitumor agent in mice. I. Systemic effects from intravenous injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213015"} {"pmid": "4213016", "title": "Corynebacterium parvum as a therapeutic antitumor agent in mice. II. Local injection.", "content": "Corynebacterium parvum as a therapeutic antitumor agent in mice. II. Local injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213016"} {"pmid": "4213017", "title": "Cross-reactivity of Neisseria gonorrhoeae and Neisseria meningitidis and the nature of antigens involved in the bactericidal reaction.", "content": "Cross-reactivity of Neisseria gonorrhoeae and Neisseria meningitidis and the nature of antigens involved in the bactericidal reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213017"} {"pmid": "4213018", "title": "Cytophilic properties of IgA to human neutrophils.", "content": "Cytophilic properties of IgA to human neutrophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213018"} {"pmid": "4213019", "title": "Cytotoxic effects of imipramine on platelets.", "content": "Cytotoxic effects of imipramine on platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213019"} {"pmid": "4213021", "title": "Demonstration of acid-base phosphorylation in chromatophores in the presence of a K+ diffusion potential.", "content": "Demonstration of acid-base phosphorylation in chromatophores in the presence of a K+ diffusion potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213021"} {"pmid": "4213020", "title": "CCNU (NSC-79037): preclinical toxicologic evaluation of a single intravenous infusion in dogs and monkeys.", "content": "CCNU (NSC-79037): preclinical toxicologic evaluation of a single intravenous infusion in dogs and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213020"} {"pmid": "4213022", "title": "Descriptive studies of a psychiatric hospital population.", "content": "Descriptive studies of a psychiatric hospital population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213022"} {"pmid": "4213023", "title": "Detection and enumeration of salmonella and pseudomonas aeruginosa.", "content": "Detection and enumeration of salmonella and pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213023"} {"pmid": "4213026", "title": "Development and use of meningococcal vaccines.", "content": "Development and use of meningococcal vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213026"} {"pmid": "4213025", "title": "Determination of the light chain type of paraproteins, identification of heavy chain disease.", "content": "Determination of the light chain type of paraproteins, identification of heavy chain disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213025"} {"pmid": "4213024", "title": "Determination of apoceruloplasmin by radioimmunoassay in nutritional copper deficiency, Menkes' kinky hair syndrome, Wilson's disease, and umbilical cord blood.", "content": "Determination of apoceruloplasmin by radioimmunoassay in nutritional copper deficiency, Menkes' kinky hair syndrome, Wilson's disease, and umbilical cord blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213024"} {"pmid": "4213027", "title": "Developmental biochemistry of bovine foetal muscle. I. DNA, RNA, dry matter and total nitrogen.", "content": "Developmental biochemistry of bovine foetal muscle. I. DNA, RNA, dry matter and total nitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213027"} {"pmid": "4213028", "title": "Diabetic acidosis and abnormal chest roentgenogram.", "content": "Diabetic acidosis and abnormal chest roentgenogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213028"} {"pmid": "4213029", "title": "Diagnosis of active tuberculosis in a university hospital.", "content": "Diagnosis of active tuberculosis in a university hospital. Active tuberculosis was diagnosed in 100 patients at Sunnybrook Medical Centre during the five-year period 1968-72. These cases were studied to find out if any delay had taken place in establishing the diagnosis and starting treatment. Delay was found most frequently when patients presented with atypical disease or when microbiological investigations were negative or misinterpreted. However, in nine patients with positive Ziehl-Neelsen smears the diagnosis was delayed more than one week. Usually such delays were caused by a failure to send specimens promptly for examination for acid-fast bacilli. Lack of communication between the laboratory and the clinician was found to be responsible for delays in starting treatment in several patients. It is essential that the clinician in a general hospital be alert to the possibility of tuberculosis and that there be close cooperation between the clinical staff and the diagnostic services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213029"} {"pmid": "4213030", "title": "Differences in the first progeny of Drosophila melanogaster strains in interspecific competition.", "content": "Differences in the first progeny of Drosophila melanogaster strains in interspecific competition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213030"} {"pmid": "4213031", "title": "Differential protein clearance in benign and malignant diseases. Application of automated immunonephelometric assay.", "content": "Differential protein clearance in benign and malignant diseases. Application of automated immunonephelometric assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213031"} {"pmid": "4213032", "title": "Differential uptake of human beta-glucuronidase isoenzymes from spleen by deficient fibroblasts.", "content": "Differential uptake of human beta-glucuronidase isoenzymes from spleen by deficient fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213032"} {"pmid": "4213033", "title": "Diphtheria deaths in the United States, 1959-1970.", "content": "Diphtheria deaths in the United States, 1959-1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213033"} {"pmid": "4213035", "title": "Distribution of human placental lactogen in the last half of normal and complicated pregnancies.", "content": "Distribution of human placental lactogen in the last half of normal and complicated pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213035"} {"pmid": "4213038", "title": "Distribution of IgA subclasses in sera and bone marrow plasma cells of 21 normal individuals.", "content": "Distribution of IgA subclasses in sera and bone marrow plasma cells of 21 normal individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213038"} {"pmid": "4213039", "title": "Disulfide bridges of human immunoglobulins A1 and A2.", "content": "Disulfide bridges of human immunoglobulins A1 and A2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213039"} {"pmid": "4213036", "title": "Distribution of repetitious sequences in chick nuclear DNA.", "content": "Distribution of repetitious sequences in chick nuclear DNA. By an improved method of hydroxylapatite chromatography, the reassociated sequences of chick nuclear DNA were isolated, and their base composition analysed. By increasing the amount of reassociation, the G + C content of the renatured sequences decreased progressively to reach a mean value corresponding to that of the total DNA. In order to study the distribution of the families, or group of families having different amount of reassociation, DNA was fractionated by CsC1 density gradient centrifugation. Fractions having different G + C content were obtained, and their reassociation rates analysed. At high C(o)t value of renaturation (C(o)t=50) the amount of reassociated sequences included in the high or in the low buoyant density DNA fractions was approximately the same, but their G + C content was as expected different. At lower C(o)t values of renaturation (between C(o)t of 0.2 and the C(o)t of 10), the results indicated an heterogeneity of the repeated sequences in the A + T rich DNA fractions, as compared to the G + C rich ones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213036"} {"pmid": "4213041", "title": "Double-blind crossover study of diphenylhydantoin in angina pectoris.", "content": "Double-blind crossover study of diphenylhydantoin in angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213041"} {"pmid": "4213040", "title": "Double paraprotein aemias (IgMK plus IgGK and IgGK plus BJL).", "content": "Double paraprotein aemias (IgMK plus IgGK and IgGK plus BJL).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213040"} {"pmid": "4213042", "title": "Drosophila rhodopsin: photochemistry, extraction and differences in the norp AP12 phototransduction mutant.", "content": "Drosophila rhodopsin: photochemistry, extraction and differences in the norp AP12 phototransduction mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213042"} {"pmid": "4213034", "title": "Directories of ambulatory health care facilities.", "content": "Directories of ambulatory health care facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213034"} {"pmid": "4213044", "title": "Early diagnosis of tuberculous meningitis.", "content": "Early diagnosis of tuberculous meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213044"} {"pmid": "4213043", "title": "Dynamics of nucleic acids and total proteins in the thymus and the bursa of Fabricius of chickens, under the action of cortisol.", "content": "Dynamics of nucleic acids and total proteins in the thymus and the bursa of Fabricius of chickens, under the action of cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213043"} {"pmid": "4213045", "title": "East coast fever: 60Co-irradiation of Theileria parva in its tick vector, Rhipicephalus appendiculatus.", "content": "East coast fever: 60Co-irradiation of Theileria parva in its tick vector, Rhipicephalus appendiculatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213045"} {"pmid": "4213046", "title": "East Coast fever: quantitative studies of Theileria parva in cattle.", "content": "East Coast fever: quantitative studies of Theileria parva in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213046"} {"pmid": "4213047", "title": "Editorial: Insulin: rates and routes of delivery.", "content": "Editorial: Insulin: rates and routes of delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213047"} {"pmid": "4213048", "title": "Editorial: Meningococcal infections.", "content": "Editorial: Meningococcal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213048"} {"pmid": "4213049", "title": "Editorial: Prolonged intravenous feeding.", "content": "Editorial: Prolonged intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213049"} {"pmid": "4213050", "title": "Editorial: Synthetic defect in ganglioside metabolism.", "content": "Editorial: Synthetic defect in ganglioside metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213050"} {"pmid": "4213051", "title": "Editorial: Therapy in genetic disease.", "content": "Editorial: Therapy in genetic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213051"} {"pmid": "4213052", "title": "Effect of antibody-complement on multiple vs. single compartment liposomes. Application of a fluorometric assay for following changes in liposomal permeability.", "content": "Effect of antibody-complement on multiple vs. single compartment liposomes. Application of a fluorometric assay for following changes in liposomal permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213052"} {"pmid": "4213053", "title": "Effect of dissolved carbon dioxide on life activity of antibiotic-producing microorganisms.", "content": "Effect of dissolved carbon dioxide on life activity of antibiotic-producing microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213053"} {"pmid": "4213054", "title": "Effect of formaldehyde, glutaraldehyde and sucrose on the tissue antigenicity.", "content": "Effect of formaldehyde, glutaraldehyde and sucrose on the tissue antigenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213054"} {"pmid": "4213056", "title": "Effect of light and temperature on the bleaching of the yellow mutant Y-1 of Euglena gracilis.", "content": "Effect of light and temperature on the bleaching of the yellow mutant Y-1 of Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213056"} {"pmid": "4213055", "title": "Effect of hypoglycemic sulfonylureas on hepatic fructose metabolism in the rat.", "content": "Effect of hypoglycemic sulfonylureas on hepatic fructose metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213055"} {"pmid": "4213057", "title": "Effect of nitroglycerin on the mechanical and metabolic performance of the isolated aerobic and hypoxic rat heart.", "content": "Effect of nitroglycerin on the mechanical and metabolic performance of the isolated aerobic and hypoxic rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213057"} {"pmid": "4213058", "title": "Effect of nitroglycerine on the quantitative ballistocardiogram.", "content": "Effect of nitroglycerine on the quantitative ballistocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213058"} {"pmid": "4213059", "title": "Effect of oxygen tension on the aldolases of Mycobacterium tuberculosis H37Rv.", "content": "Effect of oxygen tension on the aldolases of Mycobacterium tuberculosis H37Rv.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213059"} {"pmid": "4213060", "title": "Effect of penicillin irradiation on bacterial growth and penicillin resistance.", "content": "Effect of penicillin irradiation on bacterial growth and penicillin resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213060"} {"pmid": "4213061", "title": "Effect of thyrocalcitonin on the blood calcium level and degree of adhesion of the hepatocytes.", "content": "Effect of thyrocalcitonin on the blood calcium level and degree of adhesion of the hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213061"} {"pmid": "4213062", "title": "Effect of viscosity on swimming velocity of bacteria.", "content": "Effect of viscosity on swimming velocity of bacteria. A theory is given for the swimming velocity of a flagellated bacterium and its variation with the viscosity of the surrounding fluid. The theory is shown to agree fairly well with the experimental observations of Schneider and Doetsch on Pseudomonas aeruginosa for viscosities greater than 2 centipoise. However, it fails to account for the decrease of velocity observed when the viscosity decreases from 2 to 1.1 centipoise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213062"} {"pmid": "4213063", "title": "Effect of vitamin A and protein-calorie undernutrition on immune responses.", "content": "Effect of vitamin A and protein-calorie undernutrition on immune responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213063"} {"pmid": "4213065", "title": "Effect of L8027, a new potent inhibitor of prostaglandin biosynthesis, on the metabolism and response to glucagon of rat adipose tissue.", "content": "Effect of L8027, a new potent inhibitor of prostaglandin biosynthesis, on the metabolism and response to glucagon of rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213065"} {"pmid": "4213066", "title": "Effects of (-)delta 9-trans-tetrahydrocannabinol on social behavior of squirrel monkey dyads in a water competition situation.", "content": "Effects of (-)delta 9-trans-tetrahydrocannabinol on social behavior of squirrel monkey dyads in a water competition situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213066"} {"pmid": "4213067", "title": "Effects of a polychlorinated biphenyl mixture (aroclor 1254) and DDT on biliary thyroxine excretion in rats.", "content": "Effects of a polychlorinated biphenyl mixture (aroclor 1254) and DDT on biliary thyroxine excretion in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213067"} {"pmid": "4213068", "title": "Effects of an oral enzyme preparation, Chymoral, upon serum proteins associated with injury (acute phase reactants) in man.", "content": "Effects of an oral enzyme preparation, Chymoral, upon serum proteins associated with injury (acute phase reactants) in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213068"} {"pmid": "4213069", "title": "Effects of bacterial products on lymphocytes and macrophages: their possible role in natural resistance to listeria infetion in mice.", "content": "Effects of bacterial products on lymphocytes and macrophages: their possible role in natural resistance to listeria infetion in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213069"} {"pmid": "4213070", "title": "Effects of luteinizing hormone releasing hormone and thyrotrophin releasing hormone on rabbit adipose tissue.", "content": "Effects of luteinizing hormone releasing hormone and thyrotrophin releasing hormone on rabbit adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213070"} {"pmid": "4213071", "title": "Effects of positive pressure ventilation on intrarenal blood flow in infant primates.", "content": "Effects of positive pressure ventilation on intrarenal blood flow in infant primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213071"} {"pmid": "4213072", "title": "Effects of proline and hydroxyproline on amino acid levels in Drosophila.", "content": "Effects of proline and hydroxyproline on amino acid levels in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213072"} {"pmid": "4213064", "title": "Effect of C-reactive protein, PHA, PWM and choline phosphate in 3H-thymidine uptake of leukocytes of leprosy patients and normal individuals.", "content": "Effect of C-reactive protein, PHA, PWM and choline phosphate in 3H-thymidine uptake of leukocytes of leprosy patients and normal individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213064"} {"pmid": "4213074", "title": "Effects of stearic spin-labels on the photochemical activities of chromatophores from Rhodospirillum rubrum.", "content": "Effects of stearic spin-labels on the photochemical activities of chromatophores from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213074"} {"pmid": "4213073", "title": "Effects of somatostatin on the secretion of thyrotropin and prolactin.", "content": "Effects of somatostatin on the secretion of thyrotropin and prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213073"} {"pmid": "4213075", "title": "Effects of structural heterozygosity on the recovery of autosomal (II-3) translocations from x-irradiated mature and immature oocytes of Drosophila melanogaster.", "content": "Effects of structural heterozygosity on the recovery of autosomal (II-3) translocations from x-irradiated mature and immature oocytes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213075"} {"pmid": "4213076", "title": "Effects on the pituitary-thyroid axis and prolactin secretion of single and repetitive oral doses of thyrotropin-releasing hormone (TRH).", "content": "Effects on the pituitary-thyroid axis and prolactin secretion of single and repetitive oral doses of thyrotropin-releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213076"} {"pmid": "4213077", "title": "Electro-oculography.", "content": "Electro-oculography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213077"} {"pmid": "4213078", "title": "Electron microscopic appearance of dentin after decalcification and recalcification in vitro.", "content": "Electron microscopic appearance of dentin after decalcification and recalcification in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213078"} {"pmid": "4213079", "title": "Electroradioimmunoassay (ERIA): a new type of double antibody radioimmunoassay based on electroimmunodiffusion.", "content": "Electroradioimmunoassay (ERIA): a new type of double antibody radioimmunoassay based on electroimmunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213079"} {"pmid": "4213080", "title": "Endoprostheses in the treatment of femoral neck fractures.", "content": "Endoprostheses in the treatment of femoral neck fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213080"} {"pmid": "4213081", "title": "Enhancement of fat elimination during intravenous feeding.", "content": "Enhancement of fat elimination during intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213081"} {"pmid": "4213082", "title": "Enhancement of immunogenicity of a BALB-c myeloma protein in BALB-c mice.", "content": "Enhancement of immunogenicity of a BALB-c myeloma protein in BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213082"} {"pmid": "4213083", "title": "Environmental pollution, social costs, and health policy in the United States.", "content": "Environmental pollution, social costs, and health policy in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213083"} {"pmid": "4213085", "title": "Epidemiological study on brucellosis of the Mongolian People's Republic.", "content": "Epidemiological study on brucellosis of the Mongolian People's Republic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213085"} {"pmid": "4213087", "title": "Epizootiology of Minchinia nelsoni in susceptible wild oysters in Virginia, 1959 to 1971.", "content": "Epizootiology of Minchinia nelsoni in susceptible wild oysters in Virginia, 1959 to 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213087"} {"pmid": "4213088", "title": "Equilibrium dialysis.", "content": "Equilibrium dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213088"} {"pmid": "4213086", "title": "Epidemiology of selected sarcomas in children.", "content": "Epidemiology of selected sarcomas in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213086"} {"pmid": "4213089", "title": "Erosions of the skull.", "content": "Erosions of the skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213089"} {"pmid": "4213090", "title": "Erythroblastosis: the potential for eradication.", "content": "Erythroblastosis: the potential for eradication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213090"} {"pmid": "4213092", "title": "Ethylene oxide sterilization kinetics.", "content": "Ethylene oxide sterilization kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213092"} {"pmid": "4213091", "title": "Essential L-amino acids for hyperalimentation in patients with disordered nitrogen metabolism.", "content": "Essential L-amino acids for hyperalimentation in patients with disordered nitrogen metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213091"} {"pmid": "4213084", "title": "Epidemiological problems in paediatric intensive therapy and resuscitation unit.", "content": "Epidemiological problems in paediatric intensive therapy and resuscitation unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213084"} {"pmid": "4213094", "title": "Evaluation and treatment of multiple myeloma and related disorders.", "content": "Evaluation and treatment of multiple myeloma and related disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213094"} {"pmid": "4213095", "title": "Evaluation of a quantitative platelet-collagen adhesiveness test system.", "content": "Evaluation of a quantitative platelet-collagen adhesiveness test system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213095"} {"pmid": "4213096", "title": "Evaluation of the bag--CO2-generating-tablet method for isolation of Neisseria gonorrhoeae.", "content": "Evaluation of the bag--CO2-generating-tablet method for isolation of Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213096"} {"pmid": "4213098", "title": "Events surrounding the early development of Euglena chloroplasts: experiments with streptomycin in non-dividing cells.", "content": "Events surrounding the early development of Euglena chloroplasts: experiments with streptomycin in non-dividing cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213098"} {"pmid": "4213097", "title": "Events surrounding the early development of Euglena chloroplasts: cellular origins of chloroplast enzymes in euglena.", "content": "Events surrounding the early development of Euglena chloroplasts: cellular origins of chloroplast enzymes in euglena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213097"} {"pmid": "4213100", "title": "Evidence for inducible, L-malate binding proteins in the membrane of Bacillus subtilis. Identification of presumptive components of the C4-dicarboxylate transport systems.", "content": "Evidence for inducible, L-malate binding proteins in the membrane of Bacillus subtilis. Identification of presumptive components of the C4-dicarboxylate transport systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213100"} {"pmid": "4213102", "title": "Evolution of the marked chromosomes of primates: experimental evidence for centric fusion.", "content": "Evolution of the marked chromosomes of primates: experimental evidence for centric fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213102"} {"pmid": "4213103", "title": "Experimental catecholamine-induced chronic cerebral vasospasm. Myonecrosis in vessel wall.", "content": "Experimental catecholamine-induced chronic cerebral vasospasm. Myonecrosis in vessel wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213103"} {"pmid": "4213093", "title": "Ethylenediaminetetraacetate-induced release of RNA and proteins associated with ultrastructural changes in Trichomonas vaginalis.", "content": "Ethylenediaminetetraacetate-induced release of RNA and proteins associated with ultrastructural changes in Trichomonas vaginalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213093"} {"pmid": "4213104", "title": "Experimental subacute sclerosing panencephalitis in the hamster. Ultrastructure of the chronic disease.", "content": "Experimental subacute sclerosing panencephalitis in the hamster. Ultrastructure of the chronic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213104"} {"pmid": "4213105", "title": "Experimental transmission of sarcocysts from cattle to mice.", "content": "Experimental transmission of sarcocysts from cattle to mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213105"} {"pmid": "4213106", "title": "Experimental tuberculosis in lechwe antelope in Zambia.", "content": "Experimental tuberculosis in lechwe antelope in Zambia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213106"} {"pmid": "4213107", "title": "Explanation of a new CHA document: board, CEO, and medical staff relationships.", "content": "Explanation of a new CHA document: board, CEO, and medical staff relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213107"} {"pmid": "4213108", "title": "EEG and vigilance during the petit mal attack.", "content": "EEG and vigilance during the petit mal attack.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4213108"} {"pmid": "4213109", "title": "Facilitated diffusion of CO2 across albumin solutions.", "content": "Facilitated diffusion of CO2 across albumin solutions. The steady-state CO(2) flux across thin layers of 30 g/100 ml albumin solutions was measured in two different CO(2) partial pressure ranges (boundary PCO(2) values 3 and 8 torr, and 160 and 650 torr, respectively). From the data the apparent diffusion coefficient for CO(2), DCO(2), was calculated. In the high PCO(2) range a value of DCO(2) was found which is to be expected on the basis of diffusion of dissolved CO(2) only. In the low PCO(2) range DCO(2) was about 100% higher than in the high PCO(2) range, when carbonic anhydrase was present and the pH was approximately 7.7. DCO(2) depended on the concentration of carbonic anhydrase. It increased with increasing pH. It is concluded that an additional diffusion of bound CO(2) (facilitated CO(2) diffusion) occurs in the low PCO(2) range and that this transport involves the hydration of CO(2). From the diffusion coefficients in the two PCO(2) ranges the rate of facilitated diffusion was determined. Approximate calculations show that this rate (at pH 84%) diminished by exogenous spermine or spermidine. Arginine and ornithine were both converted efficiently into spermidine, but arginine was the more immediate precursor as shown by isotope competition studies and by the absence of ornithine decarboxylase and the presence of arginine decarboxylase. Exogenous putrescine was not incorporated into spermidine, although it was taken up rapidly and degraded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214102"} {"pmid": "4214104", "title": "Vitamin E deficiency anemia in Old and New World monkeys.", "content": "Vitamin E deficiency anemia in Old and New World monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214104"} {"pmid": "4214105", "title": "The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin.", "content": "The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214105"} {"pmid": "4214106", "title": "The molecular weight and properties of a neutral metallo-endopeptidase from rabbit kidney brush border.", "content": "The molecular weight and properties of a neutral metallo-endopeptidase from rabbit kidney brush border. 1. Some properties of a brush-border neutral endopeptidase purified from rabbit kidney were investigated. The peptidase was assayed by its ability to hydrolyse [(125)I]iodoinsulin B chain. 2. The enzyme was found to be homogeneous when studied in the analytical ultracentrifuge and stained as a single glycoprotein band after electrophoresis in polyacrylamide gels. 3. The molecular weight was estimated by gel filtration in columns of Sephadex G-200, by polyacrylamide-gel electrophoresis in the presence of 2-mercapto-ethanol and sodium dodecyl sulphate and by sedimentation equilibrium in the ultra-centrifuge. The estimates fell within the range 87000-96000. The mean from two sedimentation equilibrium experiments was 93000, though this estimate may be slightly inflated because of the carbohydrate component of the enzyme. No evidence of dissociation into smaller subunits was obtained in the presence of thiol, sodium dodecyl sulphate or guanidine hydrochloride. 4. The endopeptidase was maximally active at pH6.0, although in phosphate buffer, which was strongly inhibitory, an optimum above pH8 was observed. 5. The enzyme was not affected by di-isopropyl phosphofluoridate nor by several thiol reagents. It was, however, strongly inhibited by many thiols and by EDTA and other chelating agents. 6. Although activity of the EDTA-treated enzyme could be partially restored by various bivalent metal ions, the optimum concentration for its reactivation by Zn(2+) was lower than that for other ions. This metal was detected in the enzyme preparation by atomic absorption spectrophotometry in an amount equivalent to approximately one atom/mol. 7. The enzyme is the only endopeptidase shown to be located in the kidney brush border and is the first mammalian example of a neutral Zn(2+)- activated endopeptidase to be characterized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214106"} {"pmid": "4214107", "title": "The morphological and clinical features of membranoproliferative glomerulonephritis in adults.", "content": "The morphological and clinical features of membranoproliferative glomerulonephritis in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214107"} {"pmid": "4214108", "title": "Chromosomal abnormalities in a patient with adolescent myelofibrosis.", "content": "Chromosomal abnormalities in a patient with adolescent myelofibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214108"} {"pmid": "4214109", "title": "A comparison of seven strains of Lactobacillus casei var. rhamnosus in relation to their use in the microbiological assay of serum folate.", "content": "A comparison of seven strains of Lactobacillus casei var. rhamnosus in relation to their use in the microbiological assay of serum folate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214109"} {"pmid": "4214110", "title": "A simple method for the primary isolation of Mycobacterium in a carbon dioxide atmosphere.", "content": "A simple method for the primary isolation of Mycobacterium in a carbon dioxide atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214110"} {"pmid": "4214112", "title": "A simplified method for calculating dose-rate distributions from extended volumes containing gamma emitters.", "content": "A simplified method for calculating dose-rate distributions from extended volumes containing gamma emitters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214112"} {"pmid": "4214111", "title": "A simple, disposable micro-flow drip regulator.", "content": "A simple, disposable micro-flow drip regulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214111"} {"pmid": "4214113", "title": "Eclampsia during the 16th gestational week.", "content": "Eclampsia during the 16th gestational week.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214113"} {"pmid": "4214116", "title": "Human galactose 1-phosphate uridylyltransferase. Absence of half-reaction activity of galactosemic proteins.", "content": "Human galactose 1-phosphate uridylyltransferase. Absence of half-reaction activity of galactosemic proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214116"} {"pmid": "4214117", "title": "Human secretory component. I. Purification of free secretory component from colostrum.", "content": "Human secretory component. I. Purification of free secretory component from colostrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214117"} {"pmid": "4214118", "title": "An analysis by electron microscopy of intermediates in the replication of linear Tetrahymena mitochondrial DNA.", "content": "An analysis by electron microscopy of intermediates in the replication of linear Tetrahymena mitochondrial DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214118"} {"pmid": "4214119", "title": "Coronary artery syndromes after sudden propranolol withdrawal.", "content": "Coronary artery syndromes after sudden propranolol withdrawal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214119"} {"pmid": "4214120", "title": "Perinatal calf losses in a beef herd.", "content": "Perinatal calf losses in a beef herd.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214120"} {"pmid": "4214122", "title": "The natural habitat of certain primates and the problem in obtaining them for laboratory experimentation.", "content": "The natural habitat of certain primates and the problem in obtaining them for laboratory experimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214122"} {"pmid": "4214123", "title": "The natural history of diabetes.", "content": "The natural history of diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214123"} {"pmid": "4214124", "title": "Advances in research on brucellosis, 1957-1972.", "content": "Advances in research on brucellosis, 1957-1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214124"} {"pmid": "4214125", "title": "Freund's adjuvants: relationship of arthritogenicity and adjuvanticity in rats to vehicle composition.", "content": "Freund's adjuvants: relationship of arthritogenicity and adjuvanticity in rats to vehicle composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214125"} {"pmid": "4214126", "title": "Cylinder plate assay for lasalocid sodium.", "content": "Cylinder plate assay for lasalocid sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214126"} {"pmid": "4214127", "title": "An index for the judgment of optimal mating time in female cynomolgus monkeys (Macaca fascicularis).", "content": "An index for the judgment of optimal mating time in female cynomolgus monkeys (Macaca fascicularis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214127"} {"pmid": "4214129", "title": "Immune response to surface antigens of Staphylococcus aureus and their role in resistance to staphylococcal disease.", "content": "Immune response to surface antigens of Staphylococcus aureus and their role in resistance to staphylococcal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214129"} {"pmid": "4214128", "title": "Immune competence of hereditarily asplenic mice.", "content": "Immune competence of hereditarily asplenic mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214128"} {"pmid": "4214130", "title": "Hardness of finger nails in well-nourished and malnourished populations.", "content": "Hardness of finger nails in well-nourished and malnourished populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214130"} {"pmid": "4214131", "title": "Mating reaction and its daily rhythm in Euplotes crassus.", "content": "Mating reaction and its daily rhythm in Euplotes crassus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214131"} {"pmid": "4214135", "title": "Meningococcal vulvovaginitis.", "content": "Meningococcal vulvovaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214135"} {"pmid": "4214144", "title": "Widening of the paracellular pathway in the kidney tubule by a transtubular osmotic gradient. Passage of graded size non-electrolytes.", "content": "Widening of the paracellular pathway in the kidney tubule by a transtubular osmotic gradient. Passage of graded size non-electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214144"} {"pmid": "4214145", "title": "Techniques for overcoming problems of lipolytic enzymes and lipoxygenases in the preparation of plant organelles.", "content": "Techniques for overcoming problems of lipolytic enzymes and lipoxygenases in the preparation of plant organelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214145"} {"pmid": "4214147", "title": "Retino-tectal course of optic nerves in cyclopic and synophthalmic zebrafish embryos.", "content": "Retino-tectal course of optic nerves in cyclopic and synophthalmic zebrafish embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214147"} {"pmid": "4214146", "title": "Selenium in human plasma: levels in blood proteins and behavior upon dialysis, acidification, and reduction.", "content": "Selenium in human plasma: levels in blood proteins and behavior upon dialysis, acidification, and reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214146"} {"pmid": "4214148", "title": "Immunochemical characterization of Naja naja siamensis toxin and of a chemically modified toxin.", "content": "Immunochemical characterization of Naja naja siamensis toxin and of a chemically modified toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214148"} {"pmid": "4214149", "title": "Immunochemical comparisons of vertebrate glutamic acid decarboxylase.", "content": "Immunochemical comparisons of vertebrate glutamic acid decarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214149"} {"pmid": "4214150", "title": "Immunochemical method for detection of albumin in human meconium.", "content": "Immunochemical method for detection of albumin in human meconium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214150"} {"pmid": "4214151", "title": "Immunoglobulins in acute leukemia in children.", "content": "Immunoglobulins in acute leukemia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214151"} {"pmid": "4214152", "title": "Immunology and radiology.", "content": "Immunology and radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214152"} {"pmid": "4214154", "title": "Diagnostic electron microscopy of faeces. II. Acute gastroenteritis associated with reovirus-like particles.", "content": "Diagnostic electron microscopy of faeces. II. Acute gastroenteritis associated with reovirus-like particles. Virus particles resembling reoviruses or orbiviruses were found in the faeces of 40 of 73 patients under 6 years of age with acute gastroenteritis and in faeces of only two babies among 31 patients under 6 years admitted to hospital with other diagnoses. In morphology the particles resemble orbiviruses more closely than reoviruses, but differ in appearance from the orbiviruses in having a smooth, circular outline with a well marked continuous rim as seen in negatively stained preparations. They appear not to be serologically related to reovirus types 1, 2, or 3 and may be members of a new group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214154"} {"pmid": "4214155", "title": "Prognostic factors in the treatment of acute respiratory insufficiency with long-term extracorporeal oxygenation.", "content": "Prognostic factors in the treatment of acute respiratory insufficiency with long-term extracorporeal oxygenation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214155"} {"pmid": "4214157", "title": "Parenteral nutrition.", "content": "Parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214157"} {"pmid": "4214158", "title": "An interim report on osseous contour reconstruction using alloplastic materials and particulate bone grafting.", "content": "An interim report on osseous contour reconstruction using alloplastic materials and particulate bone grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214158"} {"pmid": "4214161", "title": "Mutants of Bacillus subtilis that excrete L-tryptophan. Communication I. Studies of the influence of several mutations in the genome of the revertants to histidine independence on the ability to excrete tryptophan.", "content": "Mutants of Bacillus subtilis that excrete L-tryptophan. Communication I. Studies of the influence of several mutations in the genome of the revertants to histidine independence on the ability to excrete tryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214161"} {"pmid": "4214163", "title": "An investigation into the presence of T strain mycoplasma in the male urethra.", "content": "An investigation into the presence of T strain mycoplasma in the male urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214163"} {"pmid": "4214164", "title": "Isoenzymes, multiple enzyme forms, and phylogeny.", "content": "Isoenzymes, multiple enzyme forms, and phylogeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214164"} {"pmid": "4214165", "title": "Micro cell culture method for isolation of Chlamydia trachomatis.", "content": "Micro cell culture method for isolation of Chlamydia trachomatis. Presterilized mictotiter plates (96 wells) with BHK-21 cells on 5-mm cover slips were successfully used for cell culture isolation of trachoma from 15 infected conjunctival scrapings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214165"} {"pmid": "4214166", "title": "Microbial activation of prophenoloxidase from immune insect larvae.", "content": "Microbial activation of prophenoloxidase from immune insect larvae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214166"} {"pmid": "4214167", "title": "Microbiologic aspects in patients with leukemia.", "content": "Microbiologic aspects in patients with leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214167"} {"pmid": "4214168", "title": "Microbiological studies on septicemic bullfrogs (Rana catesbeiana).", "content": "Microbiological studies on septicemic bullfrogs (Rana catesbeiana).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214168"} {"pmid": "4214169", "title": "Dislocations of the ankle without fracture.", "content": "Dislocations of the ankle without fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214169"} {"pmid": "4214170", "title": "Microcephalic dwarfism in sisters.", "content": "Microcephalic dwarfism in sisters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214170"} {"pmid": "4214171", "title": "Photochemical activity and components of membrane preparations from blue-green algae. II. Low-temperature photooxidation of cytochrome b559.", "content": "Photochemical activity and components of membrane preparations from blue-green algae. II. Low-temperature photooxidation of cytochrome b559.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214171"} {"pmid": "4214172", "title": "Glucocorticoids and thyrotropin releasing hormone (TRH) secretion.", "content": "Glucocorticoids and thyrotropin releasing hormone (TRH) secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214172"} {"pmid": "4214174", "title": "The odontogenic keratocyst--an approach to treatment.", "content": "The odontogenic keratocyst--an approach to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214174"} {"pmid": "4214175", "title": "Use of single radial immunodiffusion test for serological studies in volunteers inoculated with live attenuated influenza virus.", "content": "Use of single radial immunodiffusion test for serological studies in volunteers inoculated with live attenuated influenza virus. Pre- and post-vaccination serum samples from 278 volunteers, who were given live influenza vaccines, were tested by haemagglutination inhibition (HI) and single radial immunodiffusion tests(SRDT) for antibody to influenza A/Hong Kong/1/68 (H3N2) virus envelope antigens. Those with high antibody titres detected in both tests were less frequently infected, and 85% of the 159 infected showed rises by HI and 70% by SRDT. Similarly, 69 pairs were tested for antibody to Hong Kong (N2) neuraminidase by neuraminidase inhibition test (NI) and by SRD tests. Those with high titres in both tests resisted infection and those who were infected showed a rise in antibody detected both by NI and SRD tests. In general, SRDT was less sensitive than HI and NI in detecting antibody and antibody rises, but in some volunteers it did detect antibody rises which were not detected by conventional tests. Because of its simplicity and speed it appeared to be of use in evaluating such vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214175"} {"pmid": "4214177", "title": "Neurofibromatosis with renovascular hypertension. A case report.", "content": "Neurofibromatosis with renovascular hypertension. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214177"} {"pmid": "4214176", "title": "Neurofibromatosis and congenital heart disease.", "content": "Neurofibromatosis and congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214176"} {"pmid": "4214179", "title": "Biological deactivation of Rg seed dressing in soil.", "content": "Biological deactivation of Rg seed dressing in soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214179"} {"pmid": "4214180", "title": "Biological properties of surface components of Listeria monocytogenes (Ei factor).", "content": "Biological properties of surface components of Listeria monocytogenes (Ei factor).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214180"} {"pmid": "4214181", "title": "Biologically active components of the cells of gram-positive bacteria.", "content": "Biologically active components of the cells of gram-positive bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214181"} {"pmid": "4214183", "title": "Thyroglossal cysts and fistulae.", "content": "Thyroglossal cysts and fistulae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214183"} {"pmid": "4214182", "title": "Haemoglobin G St. José in an Italian family.", "content": "Haemoglobin G St. José in an Italian family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214182"} {"pmid": "4214185", "title": "Radioimmunoassay of thyrotropin-releasing hormone (TRH) in human plasma and urine.", "content": "Radioimmunoassay of thyrotropin-releasing hormone (TRH) in human plasma and urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214185"} {"pmid": "4214184", "title": "Thyroid tumors.", "content": "Thyroid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214184"} {"pmid": "4214187", "title": "Histological studies on the follicles with special reference to their atresia in Egyptian buffaloes.", "content": "Histological studies on the follicles with special reference to their atresia in Egyptian buffaloes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214187"} {"pmid": "4214189", "title": "A biometric study of three strains of Tetrahymena pyriformis (Ciliatea: Hymenostomatida).", "content": "A biometric study of three strains of Tetrahymena pyriformis (Ciliatea: Hymenostomatida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214189"} {"pmid": "4214191", "title": "\"Incomplete subserotypes\" and the cryptic axial filament antigen of Leptospira.", "content": "\"Incomplete subserotypes\" and the cryptic axial filament antigen of Leptospira.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214191"} {"pmid": "4214192", "title": "Seasonal prevalence of avian hematozoa in passeriform birds of Atlantic Canada.", "content": "Seasonal prevalence of avian hematozoa in passeriform birds of Atlantic Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214192"} {"pmid": "4214193", "title": "Pulmonary abnormalities in sepsis.", "content": "Pulmonary abnormalities in sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214193"} {"pmid": "4214194", "title": "Pulmonary emphysema and alpha1-antitrypsin deficiency.", "content": "Pulmonary emphysema and alpha1-antitrypsin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214194"} {"pmid": "4214195", "title": "Pulmonary host defenses in rabbits after immunization with Pseudomonas antigens: the interaction of bacteria, antibodies, macrophages, and lymphocytes.", "content": "Pulmonary host defenses in rabbits after immunization with Pseudomonas antigens: the interaction of bacteria, antibodies, macrophages, and lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214195"} {"pmid": "4214197", "title": "Preponderance of gram-positive infections during parenteral alimentation.", "content": "Preponderance of gram-positive infections during parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214197"} {"pmid": "4214198", "title": "A spondyloepiphyseal dysplasia with peripheral dysostosis.", "content": "A spondyloepiphyseal dysplasia with peripheral dysostosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214198"} {"pmid": "4214199", "title": "Pyelonephritis transferred by parabiosis.", "content": "Pyelonephritis transferred by parabiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214199"} {"pmid": "4214200", "title": "Prolonged extracorporeal cardiopulmonary support in man.", "content": "Prolonged extracorporeal cardiopulmonary support in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214200"} {"pmid": "4214201", "title": "Lesions in the cells of proximal convoluted tubules in rat kidney induced by amanitin-albumin conjugate.", "content": "Lesions in the cells of proximal convoluted tubules in rat kidney induced by amanitin-albumin conjugate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214201"} {"pmid": "4214202", "title": "Response patterns of primary vestibular neurons to thermal and rotational stimuli.", "content": "Response patterns of primary vestibular neurons to thermal and rotational stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214202"} {"pmid": "4214205", "title": "Oligonucleotides and the quaternary structure of gene-5 protein from filamentous bacteriophage.", "content": "Oligonucleotides and the quaternary structure of gene-5 protein from filamentous bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214205"} {"pmid": "4214207", "title": "Histopathology and ultrastructure of cartilage in the chondrodystrophies.", "content": "Histopathology and ultrastructure of cartilage in the chondrodystrophies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214207"} {"pmid": "4214208", "title": "Isotope techniques for studying the dynamics of nitrogen metabolism in ruminants.", "content": "Isotope techniques for studying the dynamics of nitrogen metabolism in ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214208"} {"pmid": "4214209", "title": "Postoperative oral and intravenous nutrition.", "content": "Postoperative oral and intravenous nutrition. Oral and intravenous high calorie-amino acid nutritional therapy postoperatively resulted in significant weight gain, improved colonic wound healing and maintenance of normal intravascular albumin levels. Provision of caloric needs without amino acids minimized weight loss postoperatively. However, infusion of hypertonic dextrose solutions resulted in severe generalized hepatic fatty infiltration and marked hypoalbuminemia. Protein and calorie deprivation by administration of 5% dextrose and water resulted in the greatest postoperative weight loss, reduced intravascular albumin levels and decreased colonic anastomotic strength. Comparison of oral and intravenous diet administration demonstrated that hypertonic dextrose infusion was markedly deleterious to hepatic morphology and serum protein metabolism in normal rats. Further clinical investigation appears indicated in previously well-nourished patients undergoing extensive surgery who will not be able to ingest adequate nutrients in the postoperative period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214209"} {"pmid": "4214210", "title": "Cricopharyngeal achalasia.", "content": "Cricopharyngeal achalasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214210"} {"pmid": "4214211", "title": "Pathophysiology of vitamin E deficiency in monkeys.", "content": "Pathophysiology of vitamin E deficiency in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214211"} {"pmid": "4214212", "title": "Genioplasty with reference to resorption and the hinge sliding osteotomy.", "content": "Genioplasty with reference to resorption and the hinge sliding osteotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214212"} {"pmid": "4214214", "title": "The order of replication of chromosomal markers in Pseudomonas aeruginosa strain 1. I. Marker frequency analysis by transduction.", "content": "The order of replication of chromosomal markers in Pseudomonas aeruginosa strain 1. I. Marker frequency analysis by transduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214214"} {"pmid": "4214213", "title": "Restoration of deficient edentulous ridges by bone grafting and the use of subperiosteal metal implants.", "content": "Restoration of deficient edentulous ridges by bone grafting and the use of subperiosteal metal implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214213"} {"pmid": "4214216", "title": "Editorial: Malnutrition in the hospital.", "content": "Editorial: Malnutrition in the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214216"} {"pmid": "4214217", "title": "Editorial: Sarcoidosis and tuberculosis.", "content": "Editorial: Sarcoidosis and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214217"} {"pmid": "4214215", "title": "Photoreactivation, photoproduct formation, and deoxyribonucleic acid state in ultraviolet-irradiated sporulating cultures of Bacillus cereus.", "content": "Photoreactivation, photoproduct formation, and deoxyribonucleic acid state in ultraviolet-irradiated sporulating cultures of Bacillus cereus. Photoreactivation of ultraviolet-irradiated Bacillus cereus T declined markedly during the development of stage IV forespores. During ultraviolet irradiation of a culture containing early and late stage IV forespores, both vegetative- and spore-type photoproducts were formed. The formation of vegetative-type photoproducts (mainly thymine dimers) decreased to nearly half during late stage IV, remaining constant until lysis of the mother cells began, when it fell to zero. Spore-type photoproducts were first observed during late stage IV and increased with the increase in numbers of late stage IV forespores. The occurrence of spore-type photoproducts preceded the development of refractile forespores by about 1 h. At stage III the nuclear material occupied a central position, and the ribosomes were at the periphery of the forespore protoplast. During stage IV the deoxyribonucleic acid (DNA) occurred in a peripheral position, and bundles of fibers (\"transition\" DNA) could be seen. By stage V, all of the DNA appeared to be of the spore type and was peripheral, and the forespore protoplast center was packed with ribosomes. Forespore stages II, III, and IV were classified by light and electron microscopy. The curve for electron microscope classifications preceded that for light microscope classifications by approximately one stage. The formation of spore-type photoproducts preceded differentiation of DNA by about 1 h, the latter coinciding with the development of refractility. Spore-type photoproducts have been associated with DNA in the A state, and the progressive change of the forespore DNA into this state is discussed in relation to the spore differentiation process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214215"} {"pmid": "4214218", "title": "Editorial: The management of diabetic acidosis.", "content": "Editorial: The management of diabetic acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214218"} {"pmid": "4214219", "title": "Editorial: The threat of gastro-intestinal infections in Lebanon.", "content": "Editorial: The threat of gastro-intestinal infections in Lebanon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214219"} {"pmid": "4214220", "title": "Editorial: There is more to health than just paying bills.", "content": "Editorial: There is more to health than just paying bills.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214220"} {"pmid": "4214221", "title": "Conformational properties of some viral DNAs.", "content": "Conformational properties of some viral DNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214221"} {"pmid": "4214223", "title": "Factors in human serum promoting phagocytosis of Pseudomonas aeruginosa. I. Interaction of opsonins with the bacterium.", "content": "Factors in human serum promoting phagocytosis of Pseudomonas aeruginosa. I. Interaction of opsonins with the bacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214223"} {"pmid": "4214224", "title": "Factors in human serum promoting phagocytosis of Pseudomonas aeruginosa. II. Interaction of opsonins with the phagocytic cell.", "content": "Factors in human serum promoting phagocytosis of Pseudomonas aeruginosa. II. Interaction of opsonins with the phagocytic cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214224"} {"pmid": "4214225", "title": "Factors in the mechanism of persistence of viral infections.", "content": "Factors in the mechanism of persistence of viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214225"} {"pmid": "4214228", "title": "Formosan monkey (Macaca cyclopis): present situation in Taiwan and its reproductive biology.", "content": "Formosan monkey (Macaca cyclopis): present situation in Taiwan and its reproductive biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214228"} {"pmid": "4214229", "title": "Glucose uptake and phosphorylation in Pseudomonas fluorescens.", "content": "Glucose uptake and phosphorylation in Pseudomonas fluorescens. Pseudomonas fluorescens ATCC 13525 and a particulate glucose oxidase (d-glucose:oxygen oxidoreductase, EC 1.1.3.4) mutant of this organism, gox-7, were examined to determine if glucose oxidation via particulate glucose oxidase is a required first step for glucose uptake. Initial [(14)C]glucose-uptake rates in parent and gox-7 cells were qualitatively similar. Initial [(14)C]glucose-uptake product analysis revealed that glucose was accumulated via active transport and was rapidly metabolized to glucose-6-phosphate and gluconate-6-phosphate in both parent and gox-7 cells. Cell extracts contained soluble adenosine 5'-triphosphate specific kinase activity for phosphorylation of glucose. Glucose uptake was induced by glucose and not gluconate, thus, establishing independent regulation of glucose transport and glucose catabolism in p. fluorescens. The results prove that glucose oxidase was not an obligatory reaction for glucose carbon permeation in P. fluorescens. A general unifying scheme for glucose utilization in the aerobic fluorescent pseudomonads is suggested for the purpose of clarifying glucose uptake in these bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214229"} {"pmid": "4214230", "title": "Glycosidases with unusual specificities. IV. A hydrolase that splits p-nitrophenyl-2-deoxy-2-glycylamido-beta-D-glucopyranoside: properties of the purified enzyme.", "content": "Glycosidases with unusual specificities. IV. A hydrolase that splits p-nitrophenyl-2-deoxy-2-glycylamido-beta-D-glucopyranoside: properties of the purified enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214230"} {"pmid": "4214231", "title": "Disposition of SCH 10595 in animals and man.", "content": "Disposition of SCH 10595 in animals and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214231"} {"pmid": "4214234", "title": "Amniotic fluid alpha-fetoprotein in the antenatal diagnosis of neural tube defects.", "content": "Amniotic fluid alpha-fetoprotein in the antenatal diagnosis of neural tube defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214234"} {"pmid": "4214235", "title": "The outer cell-wall membrane of Pseudomonas aeruginosa.", "content": "The outer cell-wall membrane of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214235"} {"pmid": "4214237", "title": "Improved meals for geriatric patients.", "content": "Improved meals for geriatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214237"} {"pmid": "4214236", "title": "Improved isolation and differentiation of enterococci in cheese.", "content": "Improved isolation and differentiation of enterococci in cheese. Further documentation of an enterococcus selective differential (ESD) medium was obtained in isolations from eight different cheeses. An improved differentiation of tetrazolium salt (2, 3, 5-triphenyl tetrazolium hydrochloride [TTC])-reducing strains of Streptococcus faecalis from TTC-nonreducing or TTC-faintly-reducing Streptococcus faecium was attained. The sensitivity of the medium was evaluated in comparison with that of KF streptococcal, Pfizer selective enterococcus (PSE), the medium of Reinbold, Swern, and Hussong (RSH), and the medium of Saraswat, Clark, and Reinbold (SCR). Selective counts, rate of colony formation, and ease of isolation and differentiation of colonies were examined. The specificity of the medium was also investigated. ESD supported the fastest rate of growth and the maximum size of colonies; counts in this medium were in most cases possible with 17 h of incubation, whereas the other media required 24 to 48 h. A presumptive identification of 1,077 isolates by four biochemical tests disclosed that SCR, RSH, and ESD selected high, comparable percentages of strains that approximated most closely the typical description of enterococci (66, 60.1, and 58%, respectively). Low percentages (21.1 and 30.7%) were yielded by KF and PSE. The utility of ESD for a rapid, presumptive identification of enterococci was confirmed by serological and biochemical testing of color TTC-differentiated colonies isolated from 18 cheeses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214236"} {"pmid": "4214238", "title": "Antiovulatory activity of the thyrotropin releasing hormone in the rat.", "content": "Antiovulatory activity of the thyrotropin releasing hormone in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214238"} {"pmid": "4214239", "title": "Follow-up study of 103 American soldiers who sustained a brain wound in Vietnam.", "content": "Follow-up study of 103 American soldiers who sustained a brain wound in Vietnam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214239"} {"pmid": "4214240", "title": "Non-oxygen induced retinitis proliferans and retinal detachment in full-term infants.", "content": "Non-oxygen induced retinitis proliferans and retinal detachment in full-term infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214240"} {"pmid": "4214241", "title": "The oxygenase activity of ribulose-1,5-bisphosphate carboxylase from Rhodospirillum rubrum.", "content": "The oxygenase activity of ribulose-1,5-bisphosphate carboxylase from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214241"} {"pmid": "4214233", "title": "Aminosugar-containing low molecular weight acidic compounds present in urine of normal children and of patients affected by mucopolysaccharidosis type II, 3 or IV.", "content": "Aminosugar-containing low molecular weight acidic compounds present in urine of normal children and of patients affected by mucopolysaccharidosis type II, 3 or IV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214233"} {"pmid": "4214249", "title": "Nonspecific urethritis.", "content": "Nonspecific urethritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214249"} {"pmid": "4214251", "title": "Stempellia milleri sp. n. (Microsporida: Nosematidae) in the mosquito Culex pipiens quinquefasciatus Say.", "content": "Stempellia milleri sp. n. (Microsporida: Nosematidae) in the mosquito Culex pipiens quinquefasciatus Say.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214251"} {"pmid": "4214254", "title": "Phosphorylase, 1,4-1,6-transglucosidase and UDPG-synthetase in lenses of different species.", "content": "Phosphorylase, 1,4-1,6-transglucosidase and UDPG-synthetase in lenses of different species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214254"} {"pmid": "4214255", "title": "The phospholipid-dependence of uridine diphosphate glucuronyltransferase. Effect of protein deficiency on the phospholipid composition and enzyme activity of rat liver microsomal fraction.", "content": "The phospholipid-dependence of uridine diphosphate glucuronyltransferase. Effect of protein deficiency on the phospholipid composition and enzyme activity of rat liver microsomal fraction. After force-feeding a protein-free diet to male rats for 5-7 days a substantial (2.4-fold) increase in the specific activity of the liver microsomal enzyme UDP-glucuronyltransferase (EC 2.4.1.17) was observed. A similar activation of the enzyme occurred when rats were fed on a low-protein (5%, w/w, casein) diet for 60 days. Although both the short- and long-term protein-deficient diets decreased the contents of microsomal protein and phospholipid in liver tissue they did not significantly alter the ratio of these major membrane components. Protein deficiency profoundly altered the phospholipid composition of microsomal membranes. The most striking difference in microsomal phospholipid composition between control and protein-deficient rats was their content of lysophosphatides. Whereas microsomal membranes from protein-deficient rats contained significant proportions of lysophosphatidylcholine and lysophosphatidylethanolamine very little or no lysophosphatides were detected in control preparations. Pretreatment of microsomal fractions from normal rats with phospholipase A markedly increased their UDP-glucuronyltransferase activity as did their pretreatment with lysophosphatidylcholine. It is concluded that the quantities of lysophosphatides present in microsomal membranes from protein-deficient rats were sufficient to have caused the increased UDP-glucuronyltransferase activities of these preparations. Evidence is presented suggesting that these changes in microsomal phospholipid composition and UDP-glucuronyltransferase activity caused by protein deficiency reflect changes that occur in vivo. The possible physiological significance of these findings is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214255"} {"pmid": "4214256", "title": "Scrapie.", "content": "Scrapie.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214256"} {"pmid": "4214257", "title": "The pigment complement of the photosynthetic reaction center isolated from Rhodospirillum rubrum.", "content": "The pigment complement of the photosynthetic reaction center isolated from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214257"} {"pmid": "4214258", "title": "Norepinephrine and dopamine in the limbic system of the rat.", "content": "Norepinephrine and dopamine in the limbic system of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214258"} {"pmid": "4214262", "title": "TRH potentiates behavioural changes following increased brain 5-hydroxytryptamine accumulation in rats.", "content": "TRH potentiates behavioural changes following increased brain 5-hydroxytryptamine accumulation in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214262"} {"pmid": "4214264", "title": "The present situation of Japanese monkeys in their natural habitat.", "content": "The present situation of Japanese monkeys in their natural habitat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214264"} {"pmid": "4214263", "title": "EEG prediction of brain metastases. A controlled study with neuropathological confirmation.", "content": "EEG prediction of brain metastases. A controlled study with neuropathological confirmation. A retrospective study comparing the EEG findings of two groups of patients with primary systemic malignant disease (mainly bronchial carcinoma) was carried out. One group of 13 patients (20 EEGs) had proven supratentorial cerebral metastases at necropsy, some also subtentorial, and the other group of 10 patients (15 EEGs) had no cerebral involvement at necropsy. The latter group was studied to assess the possible confusing effects in the EEG of metabolic derangements and other factors which would interfere with accurate prediction of the presence of metastases. The EEGs were masked and assessed independently by two raters using a special proforma. They found that recordings from patients with cerebral metastases had persistent focal delta activity, intermittent focal or local delta activity, persistent or intermittent lateralized delta activity, monorhythmic frontal delta activity in the alert patient, as well as a higher frequency of post-central background rhythms. These factors predicted the presence of cerebral metastases (when they were 2 cm in diameter or larger) in 12 out of the 13 patients (four of these without localized neurological disorder), the EEGs being taken on average eight weeks before death. It is concluded that the EEG is valuable in the investigation of these patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214263"} {"pmid": "4214266", "title": "The primate foveal local electroretinogram: an indicator of photoreceptor activity.", "content": "The primate foveal local electroretinogram: an indicator of photoreceptor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214266"} {"pmid": "4214265", "title": "The preservation of substance and immunological activity of intra venously injected human IgG in the mouse liver. (Comparative studies on various tissue preparation and fixation methods).", "content": "The preservation of substance and immunological activity of intra venously injected human IgG in the mouse liver. (Comparative studies on various tissue preparation and fixation methods).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214265"} {"pmid": "4214267", "title": "The problems of correction of asymmetric mandibular prognathism.", "content": "The problems of correction of asymmetric mandibular prognathism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214267"} {"pmid": "4214268", "title": "The proteolytic enzymes of the K-1 strain of Steptomyces griseus obtained from a commerical preparation (pronase). Stabilization of the trypsin component by calcium and guanidine.", "content": "The proteolytic enzymes of the K-1 strain of Steptomyces griseus obtained from a commerical preparation (pronase). Stabilization of the trypsin component by calcium and guanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214268"} {"pmid": "4214269", "title": "Streptococcus mutans endocarditis. Confusion with enterococcal endocarditis by routine laboratory testing.", "content": "Streptococcus mutans endocarditis. Confusion with enterococcal endocarditis by routine laboratory testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214269"} {"pmid": "4214270", "title": "A population screening for fetal sulfoglycoprotein antigen in gastric juice.", "content": "A population screening for fetal sulfoglycoprotein antigen in gastric juice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214270"} {"pmid": "4214271", "title": "Oblique sliding osteotomy of the mandibular rami in 55 patients with mandibular prognathism.", "content": "Oblique sliding osteotomy of the mandibular rami in 55 patients with mandibular prognathism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214271"} {"pmid": "4214272", "title": "A sequence analysis of 5 S rRNA from the blue-green alga Oscillatoria tenuis and a comparison of blue-green alga 5 S rRNA with those of bacterial and eukaryotic origin.", "content": "A sequence analysis of 5 S rRNA from the blue-green alga Oscillatoria tenuis and a comparison of blue-green alga 5 S rRNA with those of bacterial and eukaryotic origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214272"} {"pmid": "4214275", "title": "Super-active forms of placental lactogen and prolactin.", "content": "Super-active forms of placental lactogen and prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214275"} {"pmid": "4214276", "title": "Tumor-bound immunoglobulins: their possible role in circumventing antitumor immunity.", "content": "Tumor-bound immunoglobulins: their possible role in circumventing antitumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214276"} {"pmid": "4214280", "title": "Natural infection of cynomolgus monkeys with measles virus.", "content": "Natural infection of cynomolgus monkeys with measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214280"} {"pmid": "4214279", "title": "Interaction of chemical carcinogens with plasma membranes: the effect of dimethylaminoazobenzene on erythrocyte osmotic fragility.", "content": "Interaction of chemical carcinogens with plasma membranes: the effect of dimethylaminoazobenzene on erythrocyte osmotic fragility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214279"} {"pmid": "4214282", "title": "An oral surgeon's experience with the intraosseous blade implant.", "content": "An oral surgeon's experience with the intraosseous blade implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214282"} {"pmid": "4214281", "title": "Natural resistance to infection in the neonatal sheep: comparison of the ability of colostrum-deprived, normally-suckled and passively-immunized lambs to localize Erysipelothrix rhusiopathiae.", "content": "Natural resistance to infection in the neonatal sheep: comparison of the ability of colostrum-deprived, normally-suckled and passively-immunized lambs to localize Erysipelothrix rhusiopathiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214281"} {"pmid": "4214290", "title": "Laboratory animals: principles, practice and prospects.", "content": "Laboratory animals: principles, practice and prospects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214290"} {"pmid": "4214289", "title": "Separation, isolation, and immunological studies of the structural proteins of Venezuelan equine encephalomyelitis virus.", "content": "Separation, isolation, and immunological studies of the structural proteins of Venezuelan equine encephalomyelitis virus. Three viral proteins were separated from the TC-83 strain of Venezuelan equine encephalomyelitis virus by discontinuous polyacrylamide gel electrophoresis after disruption with sodium dodecyl sulfate and beta-2-mercaptoethanol. These proteins were inoculated into rabbits and the resultant antisera were tested for immunological activity by gel precipitation, plaque reduction neutralization, hemagglutination inhibition (HI), complement fixation, fluorescence microscopy, and mouse protection studies. All proteins were capable of stimulating precipitating antibody in rabbits, but the largest protein (VP 1), which is contained in the envelope, stimulated the production of detectable neutralizing and HI antibody against the intact virion. The other two proteins yielded little or no neutralizing or HI antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214289"} {"pmid": "4214292", "title": "Hyperbaric oxygen in total rehabilitation of patients with mandibular osteoradionecrosis.", "content": "Hyperbaric oxygen in total rehabilitation of patients with mandibular osteoradionecrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214292"} {"pmid": "4214293", "title": "Hypercalcaemia and mineralisation of non-osseous tissues in horses due to vitamin-D toxicity.", "content": "Hypercalcaemia and mineralisation of non-osseous tissues in horses due to vitamin-D toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214293"} {"pmid": "4214294", "title": "The reaction of anthramycin with DNA. II. Studies of kinetics and mechanism.", "content": "The reaction of anthramycin with DNA. II. Studies of kinetics and mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214294"} {"pmid": "4214296", "title": "Comprehensive outpatient respiratory care: a program conducted in a suburban private practice.", "content": "Comprehensive outpatient respiratory care: a program conducted in a suburban private practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214296"} {"pmid": "4214297", "title": "The relationship between platelets and bacteria.", "content": "The relationship between platelets and bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214297"} {"pmid": "4214301", "title": "Suppressor-sensitive mutants and genetic map of Bacillus subtilis bacteriophage phi 29.", "content": "Suppressor-sensitive mutants and genetic map of Bacillus subtilis bacteriophage phi 29.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214301"} {"pmid": "4214300", "title": "Fluorescent products and lysosomal components in aging Drosophila melanogaster.", "content": "Fluorescent products and lysosomal components in aging Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214300"} {"pmid": "4214302", "title": "Hydergine-thioridazine combination in the treatment of psychopathological states in old age.", "content": "Hydergine-thioridazine combination in the treatment of psychopathological states in old age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214302"} {"pmid": "4214303", "title": "Synergistic necrotizing myositis complicating vascular injury.", "content": "Synergistic necrotizing myositis complicating vascular injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214303"} {"pmid": "4214305", "title": "Arterial developmental anomalies of one hemisphere with inter- and intrahemispheric steal effects in neurofibromatosis (Recklinghausen's disease).", "content": "Arterial developmental anomalies of one hemisphere with inter- and intrahemispheric steal effects in neurofibromatosis (Recklinghausen's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214305"} {"pmid": "4214304", "title": "Viruria in man, an update.", "content": "Viruria in man, an update.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214304"} {"pmid": "4214307", "title": "Distribution of ABO and Rh(D) phenotypes in Uganda.", "content": "Distribution of ABO and Rh(D) phenotypes in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214307"} {"pmid": "4214306", "title": "Fimbrial haemagglutination by Neisseria gonorrhoeae.", "content": "Fimbrial haemagglutination by Neisseria gonorrhoeae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214306"} {"pmid": "4214308", "title": "Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects.", "content": "Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214308"} {"pmid": "4214309", "title": "Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes.", "content": "Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214309"} {"pmid": "4214310", "title": "Experiences in quarantine of imported monkeys.", "content": "Experiences in quarantine of imported monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214310"} {"pmid": "4214311", "title": "Experimental bacteremia due to Pseudomonas in agranulocytic animals.", "content": "Experimental bacteremia due to Pseudomonas in agranulocytic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214311"} {"pmid": "4214312", "title": "Experimental burn wound sepsis--evaluation of enzymatic debridement.", "content": "Experimental burn wound sepsis--evaluation of enzymatic debridement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214312"} {"pmid": "4214313", "title": "Experimental cerebral hemodynamics. Vasomotor tone, critical closing pressure, and vascular bed resistance.", "content": "Experimental cerebral hemodynamics. Vasomotor tone, critical closing pressure, and vascular bed resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214313"} {"pmid": "4214314", "title": "Experimental choroidal detachments.", "content": "Experimental choroidal detachments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214314"} {"pmid": "4214315", "title": "Experimental infection of dogs and monkeys with two rabies serogroup viruses, Lagos bat and Mokola (IbAn 27377). Gross pathologic and histopathologic changes.", "content": "Experimental infection of dogs and monkeys with two rabies serogroup viruses, Lagos bat and Mokola (IbAn 27377). Gross pathologic and histopathologic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214315"} {"pmid": "4214316", "title": "Experimental parathyroiditis in the rat by passive immunisation.", "content": "Experimental parathyroiditis in the rat by passive immunisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214316"} {"pmid": "4214317", "title": "Experimental pneumonia due to Pseudomonas in dogs: controlled trial of granulocyte transfusion therapy.", "content": "Experimental pneumonia due to Pseudomonas in dogs: controlled trial of granulocyte transfusion therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214317"} {"pmid": "4214318", "title": "Experimental primates in Asia. Usefulness of non-human primates: remarks from the user's viewpoint.", "content": "Experimental primates in Asia. Usefulness of non-human primates: remarks from the user's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214318"} {"pmid": "4214319", "title": "Experimental retinal detachment in owl monkeys. Effect of intravitreal hyaluronidase injection and embolization of the choroidal and retinal circulation.", "content": "Experimental retinal detachment in owl monkeys. Effect of intravitreal hyaluronidase injection and embolization of the choroidal and retinal circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214319"} {"pmid": "4214321", "title": "Veterinary nuclear medicine.", "content": "Veterinary nuclear medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214321"} {"pmid": "4214320", "title": "Experimental toxoplasmosis in the stumptailed macaque (M. arctoides).", "content": "Experimental toxoplasmosis in the stumptailed macaque (M. arctoides).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214320"} {"pmid": "4214322", "title": "Exocrine pancreatic function tests in patas monkeys (Erythrocebus patas).", "content": "Exocrine pancreatic function tests in patas monkeys (Erythrocebus patas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214322"} {"pmid": "4214323", "title": "Hyperlactataemia during intravenous feeding in childhood.", "content": "Hyperlactataemia during intravenous feeding in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214323"} {"pmid": "4214325", "title": "Intermediates in the replication of the mitochondrial DNA of Tetrahymena pyriformis.", "content": "Intermediates in the replication of the mitochondrial DNA of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214325"} {"pmid": "4214326", "title": "Determinants of reversible asynergy. Effect of pathologic Q waves, coronary collaterals, and anatomic location.", "content": "Determinants of reversible asynergy. Effect of pathologic Q waves, coronary collaterals, and anatomic location.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214326"} {"pmid": "4214327", "title": "Determination of the volume and surface area of Tetrahymena pyriformis, and their relationship to endocytosis.", "content": "Determination of the volume and surface area of Tetrahymena pyriformis, and their relationship to endocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214327"} {"pmid": "4214328", "title": "External uterine palpation to identify stages of pregnancy in the marmoset, Saguinus fuscicollis SSP.", "content": "External uterine palpation to identify stages of pregnancy in the marmoset, Saguinus fuscicollis SSP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214328"} {"pmid": "4214329", "title": "Anaerobic utilization of uric acid by some group D streptococci.", "content": "Anaerobic utilization of uric acid by some group D streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214329"} {"pmid": "4214330", "title": "Sideroblastic anaemia presenting as monoarticular arthritis.", "content": "Sideroblastic anaemia presenting as monoarticular arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214330"} {"pmid": "4214331", "title": "Arthrography of the knee after meniscectomy.", "content": "Arthrography of the knee after meniscectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214331"} {"pmid": "4214332", "title": "Filaroides cebus (Gebauer 1933)-parasitism and respiratory infections in Cebus apella.", "content": "Filaroides cebus (Gebauer 1933)-parasitism and respiratory infections in Cebus apella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214332"} {"pmid": "4214333", "title": "The role of immunoglobulin in the neutralization of trachoma infectivity.", "content": "The role of immunoglobulin in the neutralization of trachoma infectivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214333"} {"pmid": "4214335", "title": "The roles of various biochemical effects produced by 5-fluorouracil in early growth inhibition of Bacillus cereus.", "content": "The roles of various biochemical effects produced by 5-fluorouracil in early growth inhibition of Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214335"} {"pmid": "4214334", "title": "The role of Zn(II) in transcription by T7 RNA polymerase.", "content": "The role of Zn(II) in transcription by T7 RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214334"} {"pmid": "4214337", "title": "Rh prophylactic treatment during pregnancy. An attempt to select for treatment those at possible risk.", "content": "Rh prophylactic treatment during pregnancy. An attempt to select for treatment those at possible risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214337"} {"pmid": "4214338", "title": "Arthropod-borne viruses in Australia and their relation to infection and disease.", "content": "Arthropod-borne viruses in Australia and their relation to infection and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214338"} {"pmid": "4214342", "title": "Recurrent urinary tract infection. With persistent Wolffian duct masquerading as duplicated urethra.", "content": "Recurrent urinary tract infection. With persistent Wolffian duct masquerading as duplicated urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214342"} {"pmid": "4214341", "title": "Occurrence and localization of brain phenolsulphotransferase.", "content": "Occurrence and localization of brain phenolsulphotransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214341"} {"pmid": "4214343", "title": "Gonorrhea in children and adolescents: a current review.", "content": "Gonorrhea in children and adolescents: a current review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214343"} {"pmid": "4214344", "title": "Tumors of neurons and their precursors.", "content": "Tumors of neurons and their precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214344"} {"pmid": "4214347", "title": "Importation of cynomolgus monkeys: a review.", "content": "Importation of cynomolgus monkeys: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214347"} {"pmid": "4214346", "title": "Report on the differentiation of vascular wall smooth muscle cells with the aid of immunofluorescence.", "content": "Report on the differentiation of vascular wall smooth muscle cells with the aid of immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214346"} {"pmid": "4214345", "title": "Inverse relation between serum IgG concentration and glucose and xylose absorption in Zambian African adults.", "content": "Inverse relation between serum IgG concentration and glucose and xylose absorption in Zambian African adults. In three separate investigations in Zambian African adults in Lusaka an inverse association has been shown between serum IgG concentration and either glucose absorption rate from the jejunum (from a 200-mM solution) or xylose absorption (from a 25-g oral load). In developing areas of the world, where serum IgG concentrations are often high, this finding may have widespread nutritional implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214345"} {"pmid": "4214348", "title": "Hyperthermia as a teratogenic agent.", "content": "Hyperthermia as a teratogenic agent. The common cotton-eared marmoset, a nonhuman primate with a narrow zone of thermoneutrality, was used in an experiment to assess the effects of hyperthermia as a teratogenic agent. Mild heat stress conditions were used. The results of this preliminary study justify further investigation of the effect of hyperthermia on the primate embryo during morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214348"} {"pmid": "4214349", "title": "A virus-induced component of plant sap needed when aphids acquire potato virus Y from purified preparations.", "content": "A virus-induced component of plant sap needed when aphids acquire potato virus Y from purified preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214349"} {"pmid": "4214350", "title": "Observations on non-pigmented haemosporidia of Brazilian lizards, including a new species of Saurocytozoon in Mabuya mabouya (Scincidae).", "content": "Observations on non-pigmented haemosporidia of Brazilian lizards, including a new species of Saurocytozoon in Mabuya mabouya (Scincidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214350"} {"pmid": "4214353", "title": "Gross conformation of human secretory immunoglobulin A and its component parts.", "content": "Gross conformation of human secretory immunoglobulin A and its component parts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214353"} {"pmid": "4214354", "title": "Roles of conglutinin, complement, and antibody size in the card agglutination test for bovine anaplasmosis.", "content": "Roles of conglutinin, complement, and antibody size in the card agglutination test for bovine anaplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214354"} {"pmid": "4214355", "title": "Polysaccharide that may serve as a carbon and energy storage compound for sporulation in Bacillus cereus.", "content": "Polysaccharide that may serve as a carbon and energy storage compound for sporulation in Bacillus cereus. An intracellular, glucose-containing polysaccharide accumulates in Bacillus cereus early in sporulation and is degraded at the time of spore maturation. This pattern of accumulation and degradation occurred when growth was limited by glucose or a component of yeast extract. These data suggest that the polysaccharide may be serving as a carbon and energy storage compound for sporulation. A somewhat similar pattern of accumulation and degradation of poly-beta-hydroxybutyric acid (PHB) was shown earlier by Kominek and Halvorson (1965) to occur in Bacillus cereus. When cells were grown in a medium buffered strongly at pH 7.4, however, very little accumulation of PHB occurred. We have found that polysaccharide accumulates in cells grown in both the strong and weakly buffered media. Perhaps polysaccharide is the major carbon and energy storage compound when cells are grown under conditions preventing significant accumulation of PHB. The lack of polysaccharide accumulation during the exponential phase of growth may be an indication that the needed biosynthetic enzymes are controlled by catabolite repression during growth. The polysaccharide was purified and found to consist of glucose. The iodine absorption spectrum suggests a degree of branching between that of glycogen and amylopectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214355"} {"pmid": "4214356", "title": "A viscometric study of sputum glycoprotein aggregation.", "content": "A viscometric study of sputum glycoprotein aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214356"} {"pmid": "4214357", "title": "Lipase activity of detergent-resistant phospholipase A in Escherichia coli.", "content": "Lipase activity of detergent-resistant phospholipase A in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214357"} {"pmid": "4214359", "title": "The secretion of A,B,H and Lewis blood group substances in the gastric juice and saliva of chacma baboons (Papio ursinus, Kerr) and vervet monkeys (Cercopithecus pygerythrus, Cuvier.", "content": "The secretion of A,B,H and Lewis blood group substances in the gastric juice and saliva of chacma baboons (Papio ursinus, Kerr) and vervet monkeys (Cercopithecus pygerythrus, Cuvier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214359"} {"pmid": "4214361", "title": "Transfer factor therapy in a patient with chronic vaginal candidiasis.", "content": "Transfer factor therapy in a patient with chronic vaginal candidiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214361"} {"pmid": "4214362", "title": "Transfer of photosynthetically produced carbohydrate from endosymbiotic Chlorellae to Paramecium bursaria.", "content": "Transfer of photosynthetically produced carbohydrate from endosymbiotic Chlorellae to Paramecium bursaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214362"} {"pmid": "4214366", "title": "Tyrosinase in the skin of albino hamsters and mice.", "content": "Tyrosinase in the skin of albino hamsters and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214366"} {"pmid": "4214369", "title": "Parasitic protozoa of the blood of rodents: a revision of Plasmodium berghei.", "content": "Parasitic protozoa of the blood of rodents: a revision of Plasmodium berghei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214369"} {"pmid": "4214370", "title": "Transitional cell carcinoma of the bladder associated with cyclophosphamide.", "content": "Transitional cell carcinoma of the bladder associated with cyclophosphamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214370"} {"pmid": "4214371", "title": "Glossitis of military working dogs in Vietnam: experimental production of tongue lesions.", "content": "Glossitis of military working dogs in Vietnam: experimental production of tongue lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214371"} {"pmid": "4214358", "title": "A case of extradural meningioma treated successfully with high energy electron. A brief review of literature.", "content": "A case of extradural meningioma treated successfully with high energy electron. A brief review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214358"} {"pmid": "4214374", "title": "Translation of virus mRNA: synthesis of bacteriophage PP7 proteins in cell-free extracts from Pseudomonas aeruginosa.", "content": "Translation of virus mRNA: synthesis of bacteriophage PP7 proteins in cell-free extracts from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214374"} {"pmid": "4214373", "title": "Adhesive tape: potential source of nosocomial bacteria.", "content": "Adhesive tape: potential source of nosocomial bacteria. During a 7-day period, a variety of bacteria, including opportunistic ones, were recovered from 23 rolls of adhesive tape being used in a 16-bed intensive care unit. All rolls of tape were sterile when received from the manufacturer. Mixed flora was recovered from a total of 15 rolls, whereas eight rolls yielded pure cultures. Organisms recovered included Staphylococcus aureus, Pseudomonas aeruginosa, and various species of Enterobacteriaceae. Although no illness or infection arising directly from contaminated adhesive tape has been documented, we feel that a potential source of infection has been identified. Most important is the fact that such tape may contaminate the hands of personnel who handle it. Also, the adhesive tape may directly contaminate a patient since it is widely used to secure artificial airways and various drainage tubes which results in the tape coming into close contact with the mucous membranes lining the patient's respiratory and urogenital tracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214373"} {"pmid": "4214375", "title": "Autosomal dominant transmission of isolated growth hormone deficiency in iris-dental dysplasia (Rieger's syndrome).", "content": "Autosomal dominant transmission of isolated growth hormone deficiency in iris-dental dysplasia (Rieger's syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214375"} {"pmid": "4214376", "title": "Transoral surgical removal of a sialolith in the submandibular gland.", "content": "Transoral surgical removal of a sialolith in the submandibular gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214376"} {"pmid": "4214377", "title": "Transport capacity of median eminence: in vitro uptake of 3H-LRF.", "content": "Transport capacity of median eminence: in vitro uptake of 3H-LRF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214377"} {"pmid": "4214378", "title": "Transport of material between brain extracellular fluid, brain cells and blood.", "content": "Transport of material between brain extracellular fluid, brain cells and blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214378"} {"pmid": "4214379", "title": "Assessment of the carcinogenicity and mutagenicity of chemicals. Report of a WHO Scientific Group.", "content": "Assessment of the carcinogenicity and mutagenicity of chemicals. Report of a WHO Scientific Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214379"} {"pmid": "4214380", "title": "A test system for the biological safety cabinet.", "content": "A test system for the biological safety cabinet. A simple, cheap and readily available test system for biological safety cabinets is described. It depends on the containment of an aerosol of Bacillus subtilis spores generated in a BIRD micronebulizer and the measurement of air flows with an anemometer. The system was set up to survey new equipment but equally valuable results have been obtained from tests during use. New units were often badly installed and used equipment was poorly maintained. It is suggested that any department which has a need for a biological safety cabinet must be in a position to test its function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214380"} {"pmid": "4214381", "title": "Resistance of bacterial protein synthesis to double-stranded RNA.", "content": "Resistance of bacterial protein synthesis to double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214381"} {"pmid": "4214382", "title": "Resistance of Pseudomonas aeruginosa to aminoglycoside antibiotics.", "content": "Resistance of Pseudomonas aeruginosa to aminoglycoside antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214382"} {"pmid": "4214383", "title": "Resistance of Staphylococcus aureus to penicillins and cephalosporins: reversal of intrinsic resistance with some chelating agents.", "content": "Resistance of Staphylococcus aureus to penicillins and cephalosporins: reversal of intrinsic resistance with some chelating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214383"} {"pmid": "4214386", "title": "Investigations on alum-precipitated pyridine-extracted allergens. II. Sensitization studies in guinea pigs.", "content": "Investigations on alum-precipitated pyridine-extracted allergens. II. Sensitization studies in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214386"} {"pmid": "4214387", "title": "Intestinal manifestations of Fabry's disease.", "content": "Intestinal manifestations of Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214387"} {"pmid": "4214388", "title": "Schistosomiasis in Nyanza Province, Kenya, 1 Rusinga Island.", "content": "Schistosomiasis in Nyanza Province, Kenya, 1 Rusinga Island.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214388"} {"pmid": "4214389", "title": "The structural role of lipids in mitochondrial and sarcoplasmic reticulum membranes. Freeze-fracture electron microscopy studies.", "content": "The structural role of lipids in mitochondrial and sarcoplasmic reticulum membranes. Freeze-fracture electron microscopy studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214389"} {"pmid": "4214390", "title": "The study of the mutagenic properties of an insecticide from the carbamate group--Sevin.", "content": "The study of the mutagenic properties of an insecticide from the carbamate group--Sevin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214390"} {"pmid": "4214391", "title": "The substrate for integration in the central pain pathways.", "content": "The substrate for integration in the central pain pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214391"} {"pmid": "4214396", "title": "A metabolic inquiry into the iridescent lysis of agar lawns of Pseudomonas aeruginosa strain 227.", "content": "A metabolic inquiry into the iridescent lysis of agar lawns of Pseudomonas aeruginosa strain 227.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214396"} {"pmid": "4214397", "title": "Crystallisation of a modified fibrinogen.", "content": "Crystallisation of a modified fibrinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214397"} {"pmid": "4214399", "title": "Bilateral fibrous hyperplasia of the palate.", "content": "Bilateral fibrous hyperplasia of the palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214399"} {"pmid": "4214400", "title": "Counterimmunoelectrophoresis: an adjunct to bacterial culture in the diagnosis of meningococcal meningitis.", "content": "Counterimmunoelectrophoresis: an adjunct to bacterial culture in the diagnosis of meningococcal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214400"} {"pmid": "4214401", "title": "Roentgen findings of pseudo-Hurler polydystrophy in the adult, with a note on cephalometric changes.", "content": "Roentgen findings of pseudo-Hurler polydystrophy in the adult, with a note on cephalometric changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214401"} {"pmid": "4214402", "title": "Growth and development of the fetal Rhesus monkey. V. Fatty acids of phospholipids in fetal lung.", "content": "Growth and development of the fetal Rhesus monkey. V. Fatty acids of phospholipids in fetal lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214402"} {"pmid": "4214403", "title": "Health care in the United Kingdom. The changing scene.", "content": "Health care in the United Kingdom. The changing scene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214403"} {"pmid": "4214404", "title": "Growth hormone (GH)-releasing activity of TRH and GH-lowering effect of dopaminergic drugs in acromegaly: homogeneity in the two responses.", "content": "Growth hormone (GH)-releasing activity of TRH and GH-lowering effect of dopaminergic drugs in acromegaly: homogeneity in the two responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214404"} {"pmid": "4214405", "title": "Growth of the peritrich Opercularia coarctata in axenic culture.", "content": "Growth of the peritrich Opercularia coarctata in axenic culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214405"} {"pmid": "4214398", "title": "Spontaneous regression of cancer.", "content": "Spontaneous regression of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214398"} {"pmid": "4214408", "title": "Diphtheria tox+ gene expressed in corynebacterium species other than C. diphtheriae.", "content": "Diphtheria tox+ gene expressed in corynebacterium species other than C. diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214408"} {"pmid": "4214409", "title": "Lecithin-cholesterol acyltransferase activity in diabetes mellitus and the effect of insulin on these cases.", "content": "Lecithin-cholesterol acyltransferase activity in diabetes mellitus and the effect of insulin on these cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214409"} {"pmid": "4214411", "title": "Aleutian disease of mink.", "content": "Aleutian disease of mink.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214411"} {"pmid": "4214413", "title": "Genetic location of two mutations affecting the lysyl-transfer ribonucleic acid synthetase of Bacillus subtilis.", "content": "Genetic location of two mutations affecting the lysyl-transfer ribonucleic acid synthetase of Bacillus subtilis. Two mutations (lysS1 and lysS2), each independently resulting in a thermosensitive, lysyl-transfer RNA synthetase (l-lysine: tRNA ligase [adenosine 5'-monophosphate] EC 6.1.1.6), have been mapped on the Bacillus subtilis chromosome between purA16 (adenine requirement) and sul (sulfanilamide resistance). They are linked by transformation with sul (70 to 74% cotransfer) in the order purA16-lysS1-lysS2-sul. The mutant loci are either in the same gene or in two closely linked genes. They are not linked to the tryptophanyl-tRNA synthetase structural gene or to the lys-1 locus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214413"} {"pmid": "4214414", "title": "Mitotic recombination maps in Drosophila melanogaster.", "content": "Mitotic recombination maps in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214414"} {"pmid": "4214415", "title": "Genetic structure in the United Kingdom.", "content": "Genetic structure in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214415"} {"pmid": "4214416", "title": "Genetic studies on hybrid populations. 3. Blood pressure in an American black community.", "content": "Genetic studies on hybrid populations. 3. Blood pressure in an American black community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214416"} {"pmid": "4214417", "title": "Genetic transformation of biosynthetically defective Neisseria gonorrhoeae clinical isolates.", "content": "Genetic transformation of biosynthetically defective Neisseria gonorrhoeae clinical isolates. Deoxyribonucleic acid (DNA) and chemically defined media were used in transformation tests of 51 strains of Neisseria gonorrhoeae which exhibited various biosynthetic defects when isolated from patients. These auxotrophic gonococci had one or more nutritional requirements involving proline, methionine, arginine, hypoxanthine, uracil, and thiamine pyrophosphate (THPP). DNA from a clinical isolate which did not require these compounds for growth on defined medium transformed each of the auxotrophic markers of all 51 recipient populations. Ten isolates had defects involving the synthesis of THPP; four strains (designated Thp(-)) had a growth requirement that was satisfied only by THPP, whereas the requirement of six strains (designated Thi(-)) was satisfied by either thiamine or THPP. DNA from Thp(-) donors elicited transformation of Thp(-) as well as Thi(-) recipients. Reciprocally, DNA from a Thi(-) donor transformed both Thi(-) and Thp(-) recipients. Furthermore, DNA from other auxotrophic gonococci had transforming activity for some phenotypically similar auxotrophic recipients. The findings indicate the existence of various nonidentical genetic defects which block reactions in the biosynthesis of proline, methionine, arginine, hypoxanthine, and THPP. Routine cultures from patients with gonorrhea were the source of these auxotrophic strains of N. gonorrhoeae; the various nutritional requirements were identified by a recently described system of gonococcal auxotyping. The transformation test results verify the hereditary basis of the auxotypes, establish that many different mutations exist in potentially virulent gonococci, and illustrate the value of these auxotrophic mutants for studies of the genetic structure and evolution of natural populations of gonococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214417"} {"pmid": "4214418", "title": "Practicability of influenza surveillance by virus culture of children.", "content": "Practicability of influenza surveillance by virus culture of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214418"} {"pmid": "4214419", "title": "Identification of a nuclear protein matrix.", "content": "Identification of a nuclear protein matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214419"} {"pmid": "4214420", "title": "Identification of two plasmids determining resistance to tetracycline and to erythromycin in group D streptococcus.", "content": "Identification of two plasmids determining resistance to tetracycline and to erythromycin in group D streptococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214420"} {"pmid": "4214429", "title": "Dilution curves studies in coumarin plasmas and in artificially depleted abnormal control plasmas.", "content": "Dilution curves studies in coumarin plasmas and in artificially depleted abnormal control plasmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214429"} {"pmid": "4214430", "title": "Reaction of mucous membranes of the maxillary sinus and the nasal cavity to experimental periapical inflammation in monkeys.", "content": "Reaction of mucous membranes of the maxillary sinus and the nasal cavity to experimental periapical inflammation in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214430"} {"pmid": "4214431", "title": "Location of prophage H90 on the chromosome of Pseudomonas aeruginosa strain PAO.", "content": "Location of prophage H90 on the chromosome of Pseudomonas aeruginosa strain PAO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214431"} {"pmid": "4214432", "title": "Additional applications of the hexagonal conformation to calcitonin, myoglobin and other proteins of known sequence.", "content": "Additional applications of the hexagonal conformation to calcitonin, myoglobin and other proteins of known sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214432"} {"pmid": "4214433", "title": "Functionally stable osteosynthesis in the mandible.", "content": "Functionally stable osteosynthesis in the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214433"} {"pmid": "4214434", "title": "Quantitative determination of polychlorinated biphenyls--a computer approach.", "content": "Quantitative determination of polychlorinated biphenyls--a computer approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214434"} {"pmid": "4214435", "title": "Quantitative distribution of Brucella antibody amongst immunoglobulin classes in vaccinated and infected cattle.", "content": "Quantitative distribution of Brucella antibody amongst immunoglobulin classes in vaccinated and infected cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214435"} {"pmid": "4214437", "title": "Reactivity of monkey erythrocytes in immune adherence.", "content": "Reactivity of monkey erythrocytes in immune adherence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214437"} {"pmid": "4214436", "title": "Inactivation of soluble bovine milk galactosyltransferase (lactose synthetase) by sulfhydryl reagents and trypsin. Protection by substrates and products.", "content": "Inactivation of soluble bovine milk galactosyltransferase (lactose synthetase) by sulfhydryl reagents and trypsin. Protection by substrates and products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214436"} {"pmid": "4214438", "title": "Treatment of acute gonococcal urethritis in Bangkok, Thailand.", "content": "Treatment of acute gonococcal urethritis in Bangkok, Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214438"} {"pmid": "4214439", "title": "Treatment of experimentally induced Pseudomonas aeruginosa otitis externa in the dog by lavage with EDTA-tromethamine-lysozyme.", "content": "Treatment of experimentally induced Pseudomonas aeruginosa otitis externa in the dog by lavage with EDTA-tromethamine-lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214439"} {"pmid": "4214440", "title": "Treatment of facial asymmetries by one-stage maxillary and mandibular bilateral osteotomies.", "content": "Treatment of facial asymmetries by one-stage maxillary and mandibular bilateral osteotomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214440"} {"pmid": "4214443", "title": "Serotonin distribution in the limbic system of the rat.", "content": "Serotonin distribution in the limbic system of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214443"} {"pmid": "4214444", "title": "The tonotopic organization of the auditory thalamus of the squirrel monkey (Saimiri sciureus).", "content": "The tonotopic organization of the auditory thalamus of the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214444"} {"pmid": "4214446", "title": "Stentor tartari sp. n. from India.", "content": "Stentor tartari sp. n. from India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214446"} {"pmid": "4214447", "title": "Cryptosporidiosis in a calf.", "content": "Cryptosporidiosis in a calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214447"} {"pmid": "4214448", "title": "Aflatoxin Q1: a major metabolite of aflatoxin B1 produced by human liver.", "content": "Aflatoxin Q1: a major metabolite of aflatoxin B1 produced by human liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214448"} {"pmid": "4214451", "title": "The transition from tadpole to frog haemoglobin during natural amphibian metamorphosis. II. Immunofluorescence studies.", "content": "The transition from tadpole to frog haemoglobin during natural amphibian metamorphosis. II. Immunofluorescence studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214451"} {"pmid": "4214452", "title": "The treatment of anterior communicating aneurysms by proximal anterior cerebral artery ligation.", "content": "The treatment of anterior communicating aneurysms by proximal anterior cerebral artery ligation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214452"} {"pmid": "4214453", "title": "The treatment of long standing bilateral fracture non- and mal-union in atrophic edentulous mandibles.", "content": "The treatment of long standing bilateral fracture non- and mal-union in atrophic edentulous mandibles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214453"} {"pmid": "4214454", "title": "Electrocardiographic changes in Panamanian Rattus rattus naturally infected by Trypanosoma cruzi.", "content": "Electrocardiographic changes in Panamanian Rattus rattus naturally infected by Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214454"} {"pmid": "4214455", "title": "Electroencephalographic correlates of epilepsy in Nigerian children.", "content": "Electroencephalographic correlates of epilepsy in Nigerian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214455"} {"pmid": "4214458", "title": "Electron microscopy of frog photoreceptor outer segments after fixation with aldehydes.", "content": "Electron microscopy of frog photoreceptor outer segments after fixation with aldehydes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214458"} {"pmid": "4214459", "title": "Electron probe x-ray analysis of siderosomes in haemarthrotic articular cartilage.", "content": "Electron probe x-ray analysis of siderosomes in haemarthrotic articular cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214459"} {"pmid": "4214460", "title": "Electron therapy for intraocular tumours.", "content": "Electron therapy for intraocular tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214460"} {"pmid": "4214461", "title": "Rosette-forming T lymphocytes and cell-mediated immunity in malnutrition.", "content": "Rosette-forming T lymphocytes and cell-mediated immunity in malnutrition. The frequency of rosette-forming thymus-dependent lymphocytes was reduced in the peripheral blood of malnourished infants and children. The reduced frequency parallelled the impairment of delayed hypersensitivity response to 2, 4-dinitrochlorobenzene and decreased DNA synthesis by lymphocytes challenged with phytohaemagglutinin. The abnormalities were reversed on nutritional improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214461"} {"pmid": "4214463", "title": "Serotyping of Pseudomonas aeruginosa.", "content": "Serotyping of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214463"} {"pmid": "4214464", "title": "Unusual manifestations of neurofibromatosis.", "content": "Unusual manifestations of neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214464"} {"pmid": "4214465", "title": "Evaluating the potential for occurrence of aflatoxins in black sunflower seeds.", "content": "Evaluating the potential for occurrence of aflatoxins in black sunflower seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214465"} {"pmid": "4214468", "title": "Evaluation of nationwide health costs of air pollution and cigarette smoking.", "content": "Evaluation of nationwide health costs of air pollution and cigarette smoking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214468"} {"pmid": "4214467", "title": "Evaluation of commercially available antisera for serotyping of Pseudomonas aeruginosa.", "content": "Evaluation of commercially available antisera for serotyping of Pseudomonas aeruginosa. Commercially available O antisera have been compared with a standard pyocine typing method in the investigation of 156 strains of Pseudomonas aeruginosa. A third of the strains belonged to serotypes 3 or 6 and 42.3% to pyocine type 1. Good differentiation of strains belonging to the predominant serotypes was achieved by pyocine typing. Although routine use of both methods provides a more complete discrimination between strains, the simplicity of serotyping renders it more suitable for use in the smaller laboratory, where only one method may be feasible. If desired, pyocine typing can be reserved for the strains which cannot be distinguished serologically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214467"} {"pmid": "4214466", "title": "Evaluation of a simple screening test for serum anti-trypsin activity.", "content": "Evaluation of a simple screening test for serum anti-trypsin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214466"} {"pmid": "4214457", "title": "Electron beam treatment of early glottic lesions.", "content": "Electron beam treatment of early glottic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214457"} {"pmid": "4214469", "title": "Evaluation of specific protein analysis in a non-teaching hospital laboratory.", "content": "Evaluation of specific protein analysis in a non-teaching hospital laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214469"} {"pmid": "4214470", "title": "Evaluation of the gibbon (Hylobates lar lar) as a laboratory primate-use of gibbons.", "content": "Evaluation of the gibbon (Hylobates lar lar) as a laboratory primate-use of gibbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214470"} {"pmid": "4214471", "title": "Evaluation of the Gonosticon Dri Dot test in females with a low incidence of gonorrhea.", "content": "Evaluation of the Gonosticon Dri Dot test in females with a low incidence of gonorrhea. A group of 765 females attending a Planned Parenthood Clinic was screened for gonorrhea by inoculating Thayer-Martin plates and Transgrow bottles with specimens from the cervix. Blood was obtained at the same time and tested for anti-gonococcal antibody by using the Gonosticon Dri Dot test. In this low-incidence group, 18 positive cultures were detected by culture on Thayer-Martin plates, whereas Transgrow detected only 15 positive cultures. Of the 18 patients with gonorrhea, 11 exhibited reactive serum (agglutination of the latex particles). In the total population, 64% of the patients had nonreactive serum (no agglutination) and negative cultures; 25% had reactive serum and negative cultures. When this latter group was subdivided on the basis of race, blacks and Latin Americans were found to have a higher incidence of reactive serum with a corresponding negative culture than was found in whites. Patients who were originally culture positive and nonreactive in the Gonosticon Test were retested; three out of four patients retested within 6 to 11 days after the initial screening had converted to a positive Gonosticon test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214471"} {"pmid": "4214473", "title": "A double-blind trial of vitamin E in angina pectoris.", "content": "A double-blind trial of vitamin E in angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214473"} {"pmid": "4214472", "title": "Evaluation of thyroid status with \"effective thyroxine ratio\" (E.T.R.).", "content": "Evaluation of thyroid status with \"effective thyroxine ratio\" (E.T.R.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214472"} {"pmid": "4214474", "title": "Conduction defects in the aging heart.", "content": "Conduction defects in the aging heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214474"} {"pmid": "4214475", "title": "Production of extracellular substances by different virulent strains of Pseudomonas aeruginosa.", "content": "Production of extracellular substances by different virulent strains of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214475"} {"pmid": "4214476", "title": "A study of the relationship between Nocardia and Mycobacterium diernhoferi--a typical fast growing Mycobacterium.", "content": "A study of the relationship between Nocardia and Mycobacterium diernhoferi--a typical fast growing Mycobacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214476"} {"pmid": "4214477", "title": "Unique presence of 2-methylthio-ribosylzeatin in the transfer ribonucleic acid of the bacterium Pseudomonas aeruginosa.", "content": "Unique presence of 2-methylthio-ribosylzeatin in the transfer ribonucleic acid of the bacterium Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214477"} {"pmid": "4214478", "title": "Tissue pyridoxal phosphate concentration and pyridoxaminephosphate oxidase activity in riboflavin deficiency in rats and man.", "content": "Tissue pyridoxal phosphate concentration and pyridoxaminephosphate oxidase activity in riboflavin deficiency in rats and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214478"} {"pmid": "4214479", "title": "Tissue receptor for cholera exotoxin: structural requirements of G11 ganglioside in toxin binding and inactivation.", "content": "Tissue receptor for cholera exotoxin: structural requirements of G11 ganglioside in toxin binding and inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214479"} {"pmid": "4214480", "title": "Influence of glyburide on the antidiuretic response induced by 1-deamino-8-D-arginine vasopressin (DDAVP) in patients with pituitary diabetes insipidus.", "content": "Influence of glyburide on the antidiuretic response induced by 1-deamino-8-D-arginine vasopressin (DDAVP) in patients with pituitary diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214480"} {"pmid": "4214481", "title": "A fluid system for the cultivation, light microscope examination and manipulation of obligate anaerobes.", "content": "A fluid system for the cultivation, light microscope examination and manipulation of obligate anaerobes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214481"} {"pmid": "4214482", "title": "Cellular antigens of staphylococci.", "content": "Cellular antigens of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214482"} {"pmid": "4214483", "title": "Cellular mechanisms of urinary acidification.", "content": "Cellular mechanisms of urinary acidification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214483"} {"pmid": "4214484", "title": "Sporulation in Bacillus subtilis 168. Control of synthesis of alkaline phosphatase.", "content": "Sporulation in Bacillus subtilis 168. Control of synthesis of alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214484"} {"pmid": "4214486", "title": "Sodium cromoglycate BP in the prevention of exercise-induced asthma.", "content": "Sodium cromoglycate BP in the prevention of exercise-induced asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214486"} {"pmid": "4214490", "title": "Uncoupling of photophosphorylation in spinach chloroplasts by the ionophorous antibiotic A23187.", "content": "Uncoupling of photophosphorylation in spinach chloroplasts by the ionophorous antibiotic A23187.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214490"} {"pmid": "4214491", "title": "Disruption of human erythrocytes with 7-oxa-13-prostynoic acid.", "content": "Disruption of human erythrocytes with 7-oxa-13-prostynoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214491"} {"pmid": "4214493", "title": "Measurement of bound and free endotoxin by the Limulus assay.", "content": "Measurement of bound and free endotoxin by the Limulus assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214493"} {"pmid": "4214494", "title": "Measurement of urinary fibrinogen-related material: methodologic aspects.", "content": "Measurement of urinary fibrinogen-related material: methodologic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214494"} {"pmid": "4214495", "title": "Mercury effects from chronic and acute doses on fixed-interval operant behavior of female squirrel monkeys.", "content": "Mercury effects from chronic and acute doses on fixed-interval operant behavior of female squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214495"} {"pmid": "4214497", "title": "Discussion of classification.", "content": "Discussion of classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214497"} {"pmid": "4214496", "title": "The use of inactivators in the evaluation of disinfectants.", "content": "The use of inactivators in the evaluation of disinfectants. Since the earliest days of disinfectant testing bacteriostatic effect has misled many workers in this field. This problem has long been appreciated by some and a considerable battery of neutralizers has been employed, often with great success. Other anti-bacteriostatic measures, used without control, fail to revive damaged though viable organisms.This paper sets out to describe some of the problems that are encountered in this confused field and the means whereby they may be overcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214496"} {"pmid": "4214498", "title": "Computer calculations of dose for irregularly shaped fields for cobalt-60 and 6 MV photons.", "content": "Computer calculations of dose for irregularly shaped fields for cobalt-60 and 6 MV photons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214498"} {"pmid": "4214499", "title": "Agglutination of Trypanosoma cruzi by concanavalin A.", "content": "Agglutination of Trypanosoma cruzi by concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214499"} {"pmid": "4214501", "title": "The value of intravenous prostaglandin E2 after intra-uterine death.", "content": "The value of intravenous prostaglandin E2 after intra-uterine death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214501"} {"pmid": "4214500", "title": "The value of heparin in the hyperalimentation of infants and children with a fat emulsion.", "content": "The value of heparin in the hyperalimentation of infants and children with a fat emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214500"} {"pmid": "4214502", "title": "Adjuvant treatment of blunt pancreatic trauma.", "content": "Adjuvant treatment of blunt pancreatic trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214502"} {"pmid": "4214504", "title": "Activation of complement in anaphylactoid reactions in connection with infusion of dextran.", "content": "Activation of complement in anaphylactoid reactions in connection with infusion of dextran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214504"} {"pmid": "4214503", "title": "Pyruvate kinase of Streptococcus lactis.", "content": "Pyruvate kinase of Streptococcus lactis. The kinetic properties of pyruvate kinase (ATP:pyruvate-phosphotransferase, EC 2.7.1.40) from Streptococcus lactis have been investigated. Positive homotropic kinetics were observed with phosphoenolpyruvate and adenosine 5'-diphosphate, resulting in a sigmoid relationship between reaction velocity and substrate concentrations. This relationship was abolished with an excess of the heterotropic effector fructose-1,6-diphosphate, giving a typical Michaelis-Menten relationship. Increasing the concentration of fructose-1,6-diphosphate increased the apparent V(max) values and decreased the K(m) values for both substrates. Catalysis by pyruvate kinase proceeded optimally at pH 6.9 to 7.5 and was markedly inhibited by inorganic phosphate and sulfate ions. Under certain conditions adenosine 5'-triphosphate also caused inhibition. The K(m) values for phosphoenolpyruvate and adenosine 5'-diphosphate in the presence of 2 mM fructose-1,6-diphosphate were 0.17 mM and 1 mM, respectively. The concentration of fructose-1,6-diphosphate giving one-half maximal velocity with 2 mM phosphoenolpyruvate and 5 mM adenosine 5'-diphosphate was 0.07 mM. The intracellular concentrations of these metabolites (0.8 mM phosphoenolpyruvate, 2.4 mM adenosine 5'-diphosphate, and 18 mM fructose-1,6-diphosphate) suggest that the pyruvate kinase in S. lactis approaches maximal activity in exponentially growing cells. The role of pyruvate kinase in the regulation of the glycolytic pathway in lactic streptococci is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214503"} {"pmid": "4214505", "title": "Activation of lipolytic activity in Streptococcus lactis by ultraviolet irradiation.", "content": "Activation of lipolytic activity in Streptococcus lactis by ultraviolet irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214505"} {"pmid": "4214506", "title": "Active transport of choline by a marine pseudomonad.", "content": "Active transport of choline by a marine pseudomonad. A marine pseudomonad, BAL-31, accumulates the phospholipid nitrogen base, choline, although no detectable amount of choline is incorporated into polar lipids. Metabolic inhibitors such as cyanide and azide block the uptake process as does starving for oxygen by using nitrogen gas. Only very close structural analogues show any inhibition of transport, indicating that the uptake process has great structural specificity. The export of choline out of the cells is also an energy-dependent process and is markedly reduced during oxygen depletion. The constitutive level of choline transport is increased by approximately a factor of three after a brief induction period. Two other gram-negative bacteria also accumulate choline, whereas a gram-positive bacterium, Bacillus subtilis, and a yeast, Saccharomyces cerevisiae, fail to show any detectable accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214506"} {"pmid": "4214507", "title": "A novel combination of liquid chromatography and electron capture detection in the analysis of pesticides.", "content": "A novel combination of liquid chromatography and electron capture detection in the analysis of pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214507"} {"pmid": "4214508", "title": "A review of some wild land mammals of Palawan, Republic of the Philippines.", "content": "A review of some wild land mammals of Palawan, Republic of the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214508"} {"pmid": "4214509", "title": "The viruses of hepatitis.", "content": "The viruses of hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214509"} {"pmid": "4214510", "title": "The vitreous carbon tooth root replacement system: a surgical discipline.", "content": "The vitreous carbon tooth root replacement system: a surgical discipline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214510"} {"pmid": "4214514", "title": "A new fixation technique for the electron microscopic study of pulmonary surfactant.", "content": "A new fixation technique for the electron microscopic study of pulmonary surfactant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214514"} {"pmid": "4214515", "title": "A new method of gamma-ray osteodensitometry of the mandible.", "content": "A new method of gamma-ray osteodensitometry of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214515"} {"pmid": "4214516", "title": "A new species of Caryospora Léger, 1904 (Sporozoa: Eimeriidae) from an Australian snake.", "content": "A new species of Caryospora Léger, 1904 (Sporozoa: Eimeriidae) from an Australian snake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214516"} {"pmid": "4214517", "title": "A new type of sodium transport inhibitor in the toad bladder.", "content": "A new type of sodium transport inhibitor in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214517"} {"pmid": "4214518", "title": "An experimental model of alcohol feeding and liver injury in the baboon.", "content": "An experimental model of alcohol feeding and liver injury in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214518"} {"pmid": "4214520", "title": "Study of heat resistance in a bacterial nucleosidase.", "content": "Study of heat resistance in a bacterial nucleosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214520"} {"pmid": "4214519", "title": "Fatty liver and kidney syndrome in chicks. Effects on liver and kidney of diets causing the syndrome.", "content": "Fatty liver and kidney syndrome in chicks. Effects on liver and kidney of diets causing the syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214519"} {"pmid": "4214521", "title": "Study of oxacillin levels in human serum and lung tissue.", "content": "Study of oxacillin levels in human serum and lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214521"} {"pmid": "4214522", "title": "Study of the factors affecting the mutagenic activity of nitrosoethylurea.", "content": "Study of the factors affecting the mutagenic activity of nitrosoethylurea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214522"} {"pmid": "4214523", "title": "Daily variations in the production of aflatoxins by Aspergillus flavus NRRL-3145 following exposure to 60 Co irradiation.", "content": "Daily variations in the production of aflatoxins by Aspergillus flavus NRRL-3145 following exposure to 60 Co irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214523"} {"pmid": "4214525", "title": "A fly's leap from paralysis.", "content": "A fly's leap from paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214525"} {"pmid": "4214524", "title": "Assay, kinetics, and lysosomal localization of an acid cholesteryl esterase in rabbit aortic smooth muscle cells.", "content": "Assay, kinetics, and lysosomal localization of an acid cholesteryl esterase in rabbit aortic smooth muscle cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214524"} {"pmid": "4214526", "title": "Six-year follow-up of glutaraldehyde-preserved heterografts. With particular reference to the treatment of congenital valve malformations.", "content": "Six-year follow-up of glutaraldehyde-preserved heterografts. With particular reference to the treatment of congenital valve malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214526"} {"pmid": "4214528", "title": "Biosynthesis of thyrotropin releasing factor by newt (Triturus viridescens) brain in vitro. Isolation and characterization of thyrotropin releasing factor.", "content": "Biosynthesis of thyrotropin releasing factor by newt (Triturus viridescens) brain in vitro. Isolation and characterization of thyrotropin releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214528"} {"pmid": "4214529", "title": "Analysis of pharmacokinetic properties of nine tetracycline analogues in dairy cows and ewes.", "content": "Analysis of pharmacokinetic properties of nine tetracycline analogues in dairy cows and ewes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214529"} {"pmid": "4214530", "title": "Analysis of the chromosome aberrations induced by x-rays in somatic cells of Drosophila melanogaster.", "content": "Analysis of the chromosome aberrations induced by x-rays in somatic cells of Drosophila melanogaster. A technique has been perfected for enabling good microscope preparations to be obtained from the larval ganglia of Drosophila melanogaster. This system was then tested with X-rays and an extensive series of data was obtained on the chromosome aberrations induced in the various stages of the cell cycle.-The analysis of the results obtained offers the following points of interest: (1) There exists a difference in radio-sensitivity between the two sexes. The females constantly display a greater frequency of both chromosome and chromatid aberrations. They also display a greater frequency of spontaneous aberrations. (2) In both sexes the overall chromosome damage is greater in cells irradiated in stages G(2) and G(1). These two peaks of greater radiosensitivity are produced by a high frequency of terminal deletions and chromatid exchanges and by a high frequency of dicentrics, respectively. (3) The aberrations are not distributed at random among the various chromosomes. On the average, the Y chromosome is found to be more resistant and the breaks are preferentially localized in the pericentromeric heterochromatin of the X chromosome and of the autosomes. (4) Somatic pairing influences the frequency and type of the chromosome aberrations induced. In this system, such an arrangement of the chromosomes results in a high frequency of exchanges and dicentrics between homologous chromosomes and a low frequency of scorable translocations. Moreover, somatic pairing, probably by preventing the formation of looped regions in the interphase chromosomes, results in the almost total absence of intrachanges at both chromosome and chromatid level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214530"} {"pmid": "4214531", "title": "Ionizing radiations, genetic loads and population fitness, a review.", "content": "Ionizing radiations, genetic loads and population fitness, a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214531"} {"pmid": "4214532", "title": "RH (D)-isoimmunization of Japanese women.", "content": "RH (D)-isoimmunization of Japanese women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214532"} {"pmid": "4214535", "title": "Myo-Inositol dehydrogenase(s) from Acetomonas oxydans. Optimization of conditions for solubilization of membrane-bound enzyme.", "content": "Myo-Inositol dehydrogenase(s) from Acetomonas oxydans. Optimization of conditions for solubilization of membrane-bound enzyme. Methods are described for the first reported successful isolation of the soluble form of the membrane-bound myo-inositol dehydrogenase(s) from Acetomonas oxydans. Conditions for optimum yields of active enzyme in a crude membrane-free protein extract were established. The relevant conditions are (a) cell rupture by solid-shearing, (b) solubilization of the complete 60000g pellet with sodium deoxycholate at pH7.2, (c) rapid separation of the released protein from sodium deoxycholate by gel chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214535"} {"pmid": "4214536", "title": "The Kniest syndrome.", "content": "The Kniest syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214536"} {"pmid": "4214538", "title": "The N-terminal amino acid sequence of Bacillus subtilis alpha-amylase.", "content": "The N-terminal amino acid sequence of Bacillus subtilis alpha-amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214538"} {"pmid": "4214542", "title": "Antigen specificity and immunogenic capacity of 3m KCl cell extracts from ascites tumour ATPCplus.", "content": "Antigen specificity and immunogenic capacity of 3m KCl cell extracts from ascites tumour ATPCplus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214542"} {"pmid": "4214543", "title": "Immunological studies on a slow type bisalbuminae-mia (alloalbuminaemia).", "content": "Immunological studies on a slow type bisalbuminae-mia (alloalbuminaemia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214543"} {"pmid": "4214550", "title": "Lead content of neuromuscular tissue in amyotrophic lateral sclerosis: case report and other considerations.", "content": "Lead content of neuromuscular tissue in amyotrophic lateral sclerosis: case report and other considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214550"} {"pmid": "4214549", "title": "Miliary tuberculosis twice.", "content": "Miliary tuberculosis twice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214549"} {"pmid": "4214551", "title": "The relationship of extrinsic and intrinsic metal ions to the specificity of a dipeptidase from Escherichia coli B.", "content": "The relationship of extrinsic and intrinsic metal ions to the specificity of a dipeptidase from Escherichia coli B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214551"} {"pmid": "4214552", "title": "Stereospecific irreversible inhibition of histidine ammonia-lyase by L-cysteine.", "content": "Stereospecific irreversible inhibition of histidine ammonia-lyase by L-cysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214552"} {"pmid": "4214553", "title": "tRNA and tRNA aminoacyl synthetases of chloroplasts, mitochondria and cytoplasm from Euglena gracilis.", "content": "tRNA and tRNA aminoacyl synthetases of chloroplasts, mitochondria and cytoplasm from Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214553"} {"pmid": "4214554", "title": "Actinomycin D binding to 37 RC and HeLa cell lines.", "content": "Actinomycin D binding to 37 RC and HeLa cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214554"} {"pmid": "4214555", "title": "Isolation and purification of Rh(c) antigen.", "content": "Isolation and purification of Rh(c) antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214555"} {"pmid": "4214556", "title": "Haemolysis of intact human erythrocytes by purified cobra venom phospholipase A2 in the presence of albumin and Ca2+.", "content": "Haemolysis of intact human erythrocytes by purified cobra venom phospholipase A2 in the presence of albumin and Ca2+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214556"} {"pmid": "4214557", "title": "The effect of catecholamines on ion transport in the toad bladder.", "content": "The effect of catecholamines on ion transport in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214557"} {"pmid": "4214558", "title": "Protein and electroretinogram changes in the alleles of the norp AP12 Drosophila phototransduction mutant.", "content": "Protein and electroretinogram changes in the alleles of the norp AP12 Drosophila phototransduction mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214558"} {"pmid": "4214559", "title": "Some kinetic properties of M2-type pyruvate kinase from rat liver at physiological Mg2+ concentration.", "content": "Some kinetic properties of M2-type pyruvate kinase from rat liver at physiological Mg2+ concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214559"} {"pmid": "4214560", "title": "Studies on the properties of peptide hydrolases in the brush-border and soluble fractions of small intestinal mucosa of rat and man.", "content": "Studies on the properties of peptide hydrolases in the brush-border and soluble fractions of small intestinal mucosa of rat and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214560"} {"pmid": "4214561", "title": "Chicken alpha2-proteinase inhibitor: a serum protein homologous with ovoinhibitor of egg white.", "content": "Chicken alpha2-proteinase inhibitor: a serum protein homologous with ovoinhibitor of egg white.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214561"} {"pmid": "4214562", "title": "Primary platelet aggregation. Energy metabolism and the effect of inhibitors.", "content": "Primary platelet aggregation. Energy metabolism and the effect of inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214562"} {"pmid": "4214564", "title": "Purification of human serum albumin by affinity chromatography.", "content": "Purification of human serum albumin by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214564"} {"pmid": "4214563", "title": "Sequence of candicidin action on yeast cells.", "content": "Sequence of candicidin action on yeast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214563"} {"pmid": "4214565", "title": "Some hydrodynamic properties of spore peptidoglycan.", "content": "Some hydrodynamic properties of spore peptidoglycan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214565"} {"pmid": "4214566", "title": "The immunological heterogeneity of the proteins extracted from Bos taurus erythrocyte membranes by EDTA.", "content": "The immunological heterogeneity of the proteins extracted from Bos taurus erythrocyte membranes by EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214566"} {"pmid": "4214567", "title": "The mechanism of iron exchange between synthetic iron chelators and rabbit reticulocytes.", "content": "The mechanism of iron exchange between synthetic iron chelators and rabbit reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214567"} {"pmid": "4214569", "title": "Circle-elipse discrimination in monkeys: comparison of titration schedules with the method of limits.", "content": "Circle-elipse discrimination in monkeys: comparison of titration schedules with the method of limits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214569"} {"pmid": "4214570", "title": "Measurement of diffusion coefficients of meningococcal polysaccharide by optical mixing spectroscopy. I. A preliminary characterization on the aggregation of the group C polysaccharide.", "content": "Measurement of diffusion coefficients of meningococcal polysaccharide by optical mixing spectroscopy. I. A preliminary characterization on the aggregation of the group C polysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214570"} {"pmid": "4214571", "title": "Letter: Studies on the binding of amyloglucosidase to inert proteins.", "content": "Letter: Studies on the binding of amyloglucosidase to inert proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214571"} {"pmid": "4214572", "title": "An acquired inhibitor of fibrin stabilization associated with isoniazid therapy: clinical and biochemical observations.", "content": "An acquired inhibitor of fibrin stabilization associated with isoniazid therapy: clinical and biochemical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214572"} {"pmid": "4214574", "title": "Factor VIII immunological assay. An evaluation of several methods using whole plasma.", "content": "Factor VIII immunological assay. An evaluation of several methods using whole plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214574"} {"pmid": "4214575", "title": "Effect of nitroglycerin on phosphorylase activity of the myocardium.", "content": "Effect of nitroglycerin on phosphorylase activity of the myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214575"} {"pmid": "4214577", "title": "Letter: T.S.H. level and thyroid function.", "content": "Letter: T.S.H. level and thyroid function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214577"} {"pmid": "4214576", "title": "Investigation of the action of a reducing agent on the effector functions of rabbit gamma G antibodies.", "content": "Investigation of the action of a reducing agent on the effector functions of rabbit gamma G antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214576"} {"pmid": "4214578", "title": "Letter: Post-partum rubella vaccination, anti-D immunoglobulin, and blood transfusion.", "content": "Letter: Post-partum rubella vaccination, anti-D immunoglobulin, and blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214578"} {"pmid": "4214580", "title": "Letter: Safety and fibreoptic bronchoscopy.", "content": "Letter: Safety and fibreoptic bronchoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214580"} {"pmid": "4214579", "title": "Indications for systemic antibiotic prophylaxis in neutropenic patients.", "content": "Indications for systemic antibiotic prophylaxis in neutropenic patients. Four patients with malignant blood disease and neutropenia developed apparently localized infective lesions of the skin or conjunctiva from which Pseudomonas aeruginosa was cultured. In spite of appropriate local antimicrobial treatment all patients developed pseudomonas septicaemia within a short period and three died. It is argued that the isolation of pseudomonads from apparently localized lesions in patients with compromised antibacterial defences is an indication for systemic antibiotic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214579"} {"pmid": "4214582", "title": "Prostatitis after urethritis in Singapore.", "content": "Prostatitis after urethritis in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214582"} {"pmid": "4214581", "title": "Neisseria meningitidis in urogenital infection.", "content": "Neisseria meningitidis in urogenital infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214581"} {"pmid": "4214583", "title": "Letter: Prepubertal gonorrhoea.", "content": "Letter: Prepubertal gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214583"} {"pmid": "4214585", "title": "East Coast fever: titration in cattle of suspensions of Theileria parva derived from ticks.", "content": "East Coast fever: titration in cattle of suspensions of Theileria parva derived from ticks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214585"} {"pmid": "4214584", "title": "Pseudomonas aeruginosa infection in the skin of a dog: a case report.", "content": "Pseudomonas aeruginosa infection in the skin of a dog: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214584"} {"pmid": "4214591", "title": "A study on the effect of lysolecithin and phospholipase A on membrane-bound galactosyltransferase.", "content": "A study on the effect of lysolecithin and phospholipase A on membrane-bound galactosyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214591"} {"pmid": "4214592", "title": "Characterization of the esterases of feline serum.", "content": "Characterization of the esterases of feline serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214592"} {"pmid": "4214593", "title": "Template specificity and subunits of RNA polymerase from asporogenous mutants of Bacillus subtilis.", "content": "Template specificity and subunits of RNA polymerase from asporogenous mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214593"} {"pmid": "4214595", "title": "Recovery of SD chromosomes from Drosophila melanogaster males when heterozygous with structurally different second chromosomes.", "content": "Recovery of SD chromosomes from Drosophila melanogaster males when heterozygous with structurally different second chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214595"} {"pmid": "4214594", "title": "A cytokinin oxidase in Zea mays.", "content": "A cytokinin oxidase in Zea mays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214594"} {"pmid": "4214597", "title": "Characteristics of the plasma disappearance of (3H)-thyrotropin-releasing hormone in the rat.", "content": "Characteristics of the plasma disappearance of (3H)-thyrotropin-releasing hormone in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214597"} {"pmid": "4214596", "title": "Surgery in premalignant lesions.", "content": "Surgery in premalignant lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214596"} {"pmid": "4214598", "title": "Effects of guanethidine and imidazole on histamine metabolism.", "content": "Effects of guanethidine and imidazole on histamine metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214598"} {"pmid": "4214599", "title": "The isolation of Neisseria species from unusual sites.", "content": "The isolation of Neisseria species from unusual sites. The isolation of N. gonorrhoeae from the pharynx of four patients and N. meningitidis from the genital tract of six patients is described. Sexual transmission seemed the most likely means of acquiring these organisms. Three out of four patients harbouring gonococci in the pharynx were asymptomatic, while four of six patients with genital meningococci were symptom-free. The isolation of meningococci from the genital tract coincided with an unusually high incidence of meningococcal disease in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214599"} {"pmid": "4214600", "title": "Diffuse plasma cell infiltration of the small intestine with malabsorption associated to IgA monoclonal gammapathy.", "content": "Diffuse plasma cell infiltration of the small intestine with malabsorption associated to IgA monoclonal gammapathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214600"} {"pmid": "4214601", "title": "Lymphomatoid granulomatosis of the skin: light microscopic and ultrastructural studies.", "content": "Lymphomatoid granulomatosis of the skin: light microscopic and ultrastructural studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214601"} {"pmid": "4214602", "title": "IgG myeloma, Sia test, and serum hyperviscosity.", "content": "IgG myeloma, Sia test, and serum hyperviscosity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214602"} {"pmid": "4214603", "title": "Spontaneous haemophilia in a genotypically normal female. A family study.", "content": "Spontaneous haemophilia in a genotypically normal female. A family study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214603"} {"pmid": "4214604", "title": "Disseminated intravascular coagulation during a fatal Mycoplasma pneumoniae infection.", "content": "Disseminated intravascular coagulation during a fatal Mycoplasma pneumoniae infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214604"} {"pmid": "4214606", "title": "Serum concentrations of haptoglobin and hemopexin in favism and thalassemia.", "content": "Serum concentrations of haptoglobin and hemopexin in favism and thalassemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214606"} {"pmid": "4214607", "title": "Experimental study on haematotoxic and leukaemogenic effects of trichlorophone and dimethoate.", "content": "Experimental study on haematotoxic and leukaemogenic effects of trichlorophone and dimethoate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214607"} {"pmid": "4214609", "title": "Study of post-splenectomy thrombocytopoiesis with 75Se-methionine in mice.", "content": "Study of post-splenectomy thrombocytopoiesis with 75Se-methionine in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214609"} {"pmid": "4214610", "title": "Functional characteristics of chronic monocytic \"leukemia\".", "content": "Functional characteristics of chronic monocytic \"leukemia\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214610"} {"pmid": "4214611", "title": "Solubilization and activation of mammalian melanoma particulate tyrosinase by lipase digestion.", "content": "Solubilization and activation of mammalian melanoma particulate tyrosinase by lipase digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214611"} {"pmid": "4214612", "title": "Occurrence of Mason-Pfizer monkey virus in healthy rhesus monkeys.", "content": "Occurrence of Mason-Pfizer monkey virus in healthy rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214612"} {"pmid": "4214605", "title": "Letter: Potential hazards associated with the use of 1-methyl-1-nitrosourea (NSC-23909).", "content": "Letter: Potential hazards associated with the use of 1-methyl-1-nitrosourea (NSC-23909).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214605"} {"pmid": "4214613", "title": "An assay for iduronate sulfatase (Hunter corrective factor).", "content": "An assay for iduronate sulfatase (Hunter corrective factor).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214613"} {"pmid": "4214614", "title": "Biosynthesis of chondroitin sulfate. Purification of UDP-D-xylose:core protein beta-D-xylosyltransferase by affinity chromatography.", "content": "Biosynthesis of chondroitin sulfate. Purification of UDP-D-xylose:core protein beta-D-xylosyltransferase by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214614"} {"pmid": "4214615", "title": "Cross-reactivity of the membrane teichoic acid of Streptococcus faecalis N.C.I.B. 8191 in antipneumococcal type XII and type XVI sera.", "content": "Cross-reactivity of the membrane teichoic acid of Streptococcus faecalis N.C.I.B. 8191 in antipneumococcal type XII and type XVI sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214615"} {"pmid": "4214608", "title": "Central nervous system complications after combination treatment with adriamycin (NSC-123127) and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388).", "content": "Central nervous system complications after combination treatment with adriamycin (NSC-123127) and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214608"} {"pmid": "4214616", "title": "The possible biological significance of Fc receptors on mammalian lymphocytes and tumor cells.", "content": "The possible biological significance of Fc receptors on mammalian lymphocytes and tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214616"} {"pmid": "4214617", "title": "Relative activities of alpha-ecdysone and beta-ecdysone for the differentiation in vitro of Drosophila melanogaster imaginal discs.", "content": "Relative activities of alpha-ecdysone and beta-ecdysone for the differentiation in vitro of Drosophila melanogaster imaginal discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214617"} {"pmid": "4214618", "title": "A hemagglutination inhibition technique for detection of immunoglobulins in supernatants of human lymphoblastoid cell lines.", "content": "A hemagglutination inhibition technique for detection of immunoglobulins in supernatants of human lymphoblastoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214618"} {"pmid": "4214619", "title": "The program of protein synthesis during heterocyst differentiation in nitrogen-fixing blue-green algae.", "content": "The program of protein synthesis during heterocyst differentiation in nitrogen-fixing blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214619"} {"pmid": "4214623", "title": "Studies on the passage of alpha-chymotrypsin across the intestine. III. Quantitation of alpha-chymotrypsin in the mesenteric perfusate by single radial immunodiffusion.", "content": "Studies on the passage of alpha-chymotrypsin across the intestine. III. Quantitation of alpha-chymotrypsin in the mesenteric perfusate by single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214623"} {"pmid": "4214626", "title": "Regional myocardial function during acute coronary artery occlusion and its modification by pharmacologic agents in the dog.", "content": "Regional myocardial function during acute coronary artery occlusion and its modification by pharmacologic agents in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214626"} {"pmid": "4214627", "title": "Constrictive pericarditis in childhood due to mediastinal irradiation.", "content": "Constrictive pericarditis in childhood due to mediastinal irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214627"} {"pmid": "4214628", "title": "Evaluation of the ability of echocardiography to measure acute alterations in left ventricular volume.", "content": "Evaluation of the ability of echocardiography to measure acute alterations in left ventricular volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214628"} {"pmid": "4214629", "title": "Maximum treadmill exercise electrocardiography in female patients.", "content": "Maximum treadmill exercise electrocardiography in female patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214629"} {"pmid": "4214630", "title": "Chagasic cardiopathy. Antibodies reacting with plasma membrane of striated muscle and endothelial cells.", "content": "Chagasic cardiopathy. Antibodies reacting with plasma membrane of striated muscle and endothelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214630"} {"pmid": "4214631", "title": "Letter: The action of nitroglycerin.", "content": "Letter: The action of nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214631"} {"pmid": "4214632", "title": "Anaphylactic sensitivity to human seminal fluid.", "content": "Anaphylactic sensitivity to human seminal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214632"} {"pmid": "4214633", "title": "Glutaraldehyde-pollen-tyrosine: clinical and immunological studies.", "content": "Glutaraldehyde-pollen-tyrosine: clinical and immunological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214633"} {"pmid": "4214634", "title": "IgE--antibodies and skin test reactions to a detergent--enzyme in Swedish consumers.", "content": "IgE--antibodies and skin test reactions to a detergent--enzyme in Swedish consumers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214634"} {"pmid": "4214635", "title": "Emergence of basophils at sites of local allergic reactions using a skin vesicle test.", "content": "Emergence of basophils at sites of local allergic reactions using a skin vesicle test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214635"} {"pmid": "4214637", "title": "A note on the estimation of thyroxine-binding parameters.", "content": "A note on the estimation of thyroxine-binding parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214637"} {"pmid": "4214636", "title": "Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride.", "content": "Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214636"} {"pmid": "4214638", "title": "Prolactin, TSH, LH and FSH responses to a combined LHRH-TRH test at different stages of the menstrual cycle.", "content": "Prolactin, TSH, LH and FSH responses to a combined LHRH-TRH test at different stages of the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214638"} {"pmid": "4214639", "title": "Electromyography of oral-facial musculature in craniocarpaltarsal dysplasia (Freeman-Sheldon syndrome).", "content": "Electromyography of oral-facial musculature in craniocarpaltarsal dysplasia (Freeman-Sheldon syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214639"} {"pmid": "4214641", "title": "Absorption and decomposition of potassium-35S-phenoxymethyl penicillin.", "content": "Absorption and decomposition of potassium-35S-phenoxymethyl penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214641"} {"pmid": "4214640", "title": "A linkage study of phenylketonuria.", "content": "A linkage study of phenylketonuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214640"} {"pmid": "4214642", "title": "Burns in children.", "content": "Burns in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214642"} {"pmid": "4214643", "title": "Detection of mucopolysaccharidoses by sulphate incorporation into stimulated lymphocytes.", "content": "Detection of mucopolysaccharidoses by sulphate incorporation into stimulated lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214643"} {"pmid": "4214645", "title": "L-leucyl-and L-phenylalanyl-beta-naphthylamidase activities in the tissues of the sea mussel (Mytilus edulis L.).", "content": "L-leucyl-and L-phenylalanyl-beta-naphthylamidase activities in the tissues of the sea mussel (Mytilus edulis L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214645"} {"pmid": "4214647", "title": "Serum protein relationships among several species of Galapagos lava lizards (genus Tropidurus).", "content": "Serum protein relationships among several species of Galapagos lava lizards (genus Tropidurus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214647"} {"pmid": "4214646", "title": "The soluble cuticular proteins form three arthropod species: Scylla serrata (Decapoda: Portunidae), Boophilus microplus (Acarina: Ixodidae) and Agrianome spinicollis (Coleoptera: Cerambycidae).", "content": "The soluble cuticular proteins form three arthropod species: Scylla serrata (Decapoda: Portunidae), Boophilus microplus (Acarina: Ixodidae) and Agrianome spinicollis (Coleoptera: Cerambycidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214646"} {"pmid": "4214649", "title": "Staphylococcal alpha antitoxin and antibodies to extracellular antigens of staphylococci and micrococci in the serums of dairy cows.", "content": "Staphylococcal alpha antitoxin and antibodies to extracellular antigens of staphylococci and micrococci in the serums of dairy cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214649"} {"pmid": "4214651", "title": "Low-dose haloperidol as antiemetic treatment in gastrointestinal disorders: a double-blind study.", "content": "Low-dose haloperidol as antiemetic treatment in gastrointestinal disorders: a double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214651"} {"pmid": "4214650", "title": "\"Psychotropic\" action of sex hormones: computerized EEG in establishing the immediate CNS effects of steroid hormones.", "content": "\"Psychotropic\" action of sex hormones: computerized EEG in establishing the immediate CNS effects of steroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214650"} {"pmid": "4214652", "title": "Psychomotor effects of a new CNS stimulant, Abbott 34519.", "content": "Psychomotor effects of a new CNS stimulant, Abbott 34519.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214652"} {"pmid": "4214653", "title": "Controlled trial of guanethidine and methyldopa in moderate hypertension.", "content": "Controlled trial of guanethidine and methyldopa in moderate hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214653"} {"pmid": "4214654", "title": "Circulatory effects of fenfluramine in obese hypertensive patients.", "content": "Circulatory effects of fenfluramine in obese hypertensive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214654"} {"pmid": "4214655", "title": "Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment.", "content": "Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214655"} {"pmid": "4214656", "title": "Pharmaceutics of cephapirin sodium (Cefadyl) a new semisynthetic cephalosporin - part III.", "content": "Pharmaceutics of cephapirin sodium (Cefadyl) a new semisynthetic cephalosporin - part III.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214656"} {"pmid": "4214648", "title": "Psychological characteristics of long-term mental patients: some implications for treatment.", "content": "Psychological characteristics of long-term mental patients: some implications for treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214648"} {"pmid": "4214657", "title": "A system for clinical drug development in the United States.", "content": "A system for clinical drug development in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214657"} {"pmid": "4214658", "title": "A double-blind comparison of pimozide vs. trifluoperazine in schizophrenic outpatients.", "content": "A double-blind comparison of pimozide vs. trifluoperazine in schizophrenic outpatients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214658"} {"pmid": "4214660", "title": "The effects of dimethyl sulfoxide on snake venom toxicity in vivo and on the efficacy of antivenins.", "content": "The effects of dimethyl sulfoxide on snake venom toxicity in vivo and on the efficacy of antivenins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214660"} {"pmid": "4214659", "title": "A comparison of the relative clinical efficacy of two chlorpromazine (CPZ) preparations.", "content": "A comparison of the relative clinical efficacy of two chlorpromazine (CPZ) preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214659"} {"pmid": "4214661", "title": "Minocycline administered intravenously: pharmacological activity and clinical experience.", "content": "Minocycline administered intravenously: pharmacological activity and clinical experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214661"} {"pmid": "4214662", "title": "Pharmacokinetics of cefazolin, a new cephalosporin antibiotic, in normal and uraemic patients.", "content": "Pharmacokinetics of cefazolin, a new cephalosporin antibiotic, in normal and uraemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214662"} {"pmid": "4214663", "title": "Antihypertensive effects of metolazone (zaroxolyn).", "content": "Antihypertensive effects of metolazone (zaroxolyn).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214663"} {"pmid": "4214664", "title": "Long-term effect of halofenate on serum lipids.", "content": "Long-term effect of halofenate on serum lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214664"} {"pmid": "4214665", "title": "Comparative study of bufexamac (Droxaryl) ointment and of its excipient on psoriasis cases: double-blind test.", "content": "Comparative study of bufexamac (Droxaryl) ointment and of its excipient on psoriasis cases: double-blind test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214665"} {"pmid": "4214666", "title": "Etiology and management of intestinal gas.", "content": "Etiology and management of intestinal gas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214666"} {"pmid": "4214667", "title": "Acetaminophen with codeine for the relief of severe pain in postpartum patients.", "content": "Acetaminophen with codeine for the relief of severe pain in postpartum patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214667"} {"pmid": "4214669", "title": "The effect of Ru-Vert and its components on post-rotatory motor performance.", "content": "The effect of Ru-Vert and its components on post-rotatory motor performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214669"} {"pmid": "4214668", "title": "Treatment of musculoskeletal pain and associated anxiety with an ethoheptazine-aspirin-meprobamate combination (equagesic): a controlled study.", "content": "Treatment of musculoskeletal pain and associated anxiety with an ethoheptazine-aspirin-meprobamate combination (equagesic): a controlled study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214668"} {"pmid": "4214670", "title": "Comparison of triazolam, flurazepam and placebo as hypnotic agents in pre-surgical patients.", "content": "Comparison of triazolam, flurazepam and placebo as hypnotic agents in pre-surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214670"} {"pmid": "4214671", "title": "Triazolam: a new benzodiazepine hypnotic and its effect on mood.", "content": "Triazolam: a new benzodiazepine hypnotic and its effect on mood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214671"} {"pmid": "4214672", "title": "A transcultural study with clomacran: comparison of two assessment methods.", "content": "A transcultural study with clomacran: comparison of two assessment methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214672"} {"pmid": "4214673", "title": "Comparison of thiopropazate and trifluoperazine on oral dyskinesia - a double blind study.", "content": "Comparison of thiopropazate and trifluoperazine on oral dyskinesia - a double blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214673"} {"pmid": "4214674", "title": "A double-blind comparison of pimozide and chlorpromazine in the maintenance care of chronic schizophrenic outpatients.", "content": "A double-blind comparison of pimozide and chlorpromazine in the maintenance care of chronic schizophrenic outpatients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214674"} {"pmid": "4214675", "title": "Sex-chromosome replication in blood cells of XX-XY chimeric marmosets.", "content": "Sex-chromosome replication in blood cells of XX-XY chimeric marmosets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214675"} {"pmid": "4214676", "title": "Serum protein paper electrophoresis in cystic fibrosis correlated with bacteriological lung findings.", "content": "Serum protein paper electrophoresis in cystic fibrosis correlated with bacteriological lung findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214676"} {"pmid": "4214677", "title": "Restoration of regional wall motion by nitroglycerin therapy in patients with left ventricular asynergy.", "content": "Restoration of regional wall motion by nitroglycerin therapy in patients with left ventricular asynergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214677"} {"pmid": "4214679", "title": "Experimental study for rapid sterilization of the flexible fiberoptic bronchoscope.", "content": "Experimental study for rapid sterilization of the flexible fiberoptic bronchoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214679"} {"pmid": "4214678", "title": "Pulmonary monosporosis: report of a case with precipitating antibody.", "content": "Pulmonary monosporosis: report of a case with precipitating antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214678"} {"pmid": "4214681", "title": "Spontaneous chromosome rearrangements in an established cell line of Drosophila melanogaster.", "content": "Spontaneous chromosome rearrangements in an established cell line of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214681"} {"pmid": "4214682", "title": "Initial phases of DNA synthesis in Drosophila melanogaster. I. Differential participation in replication of the X chromosomes in males and females.", "content": "Initial phases of DNA synthesis in Drosophila melanogaster. I. Differential participation in replication of the X chromosomes in males and females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214682"} {"pmid": "4214683", "title": "Replicating DNA molecules from fertilized eggs of Cochliomyia hominivorax (Diptera).", "content": "Replicating DNA molecules from fertilized eggs of Cochliomyia hominivorax (Diptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214683"} {"pmid": "4214687", "title": "The metabolic fate of cyclophosphamide.", "content": "The metabolic fate of cyclophosphamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214687"} {"pmid": "4214692", "title": "An assay for growth hormone and prolactin-releasing activities using a bovine pituitary cell culture system.", "content": "An assay for growth hormone and prolactin-releasing activities using a bovine pituitary cell culture system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214692"} {"pmid": "4214693", "title": "In vivo effects of prostaglandins on TRH-induced TSH secretion.", "content": "In vivo effects of prostaglandins on TRH-induced TSH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214693"} {"pmid": "4214694", "title": "Effect of catecholamines on the TRH-stimulated release of prolactin and growth hormone from sheep pituitaries in vitro.", "content": "Effect of catecholamines on the TRH-stimulated release of prolactin and growth hormone from sheep pituitaries in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214694"} {"pmid": "4214695", "title": "The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.", "content": "The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214695"} {"pmid": "4214696", "title": "The effect of subpial vertical cortical incisions on a cobalt-gelatin focus.", "content": "The effect of subpial vertical cortical incisions on a cobalt-gelatin focus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214696"} {"pmid": "4214697", "title": "Circulatory and respiratory changes in spontaneous epileptic seizures in man.", "content": "Circulatory and respiratory changes in spontaneous epileptic seizures in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214697"} {"pmid": "4214698", "title": "Dispersion pattern of visual evoked responses in epilepsy.", "content": "Dispersion pattern of visual evoked responses in epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214698"} {"pmid": "4214699", "title": "Optimal antibiotic therapy for infections in patients with cancer: prospects for the future.", "content": "Optimal antibiotic therapy for infections in patients with cancer: prospects for the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214699"} {"pmid": "4214700", "title": "Changing patterns of infection in cancer patients.", "content": "Changing patterns of infection in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214700"} {"pmid": "4214701", "title": "Administration of carbenicillin and ticarcillin--pharmaceutical aspects.", "content": "Administration of carbenicillin and ticarcillin--pharmaceutical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214701"} {"pmid": "4214702", "title": "Antipseudomonal drugs: comparative study of gentamicin, sisomicin and tobramycin in vitro and in human volunteers.", "content": "Antipseudomonal drugs: comparative study of gentamicin, sisomicin and tobramycin in vitro and in human volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214702"} {"pmid": "4214703", "title": "The dynamic state of the macrophage plasma membrane. Attachment and fate of immunoglobulin, antigen and lectins.", "content": "The dynamic state of the macrophage plasma membrane. Attachment and fate of immunoglobulin, antigen and lectins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214703"} {"pmid": "4214704", "title": "An allotypic marker on chicken immunoglobulin M.", "content": "An allotypic marker on chicken immunoglobulin M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214704"} {"pmid": "4214705", "title": "Interference of oral immunization with the intestinal absorption of heterologous albumin.", "content": "Interference of oral immunization with the intestinal absorption of heterologous albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214705"} {"pmid": "4214706", "title": "Inhibition of mitogenic stimulation of mouse lymphocytes by anti-mouse immunoglobulin antibodies. I. Mode of action.", "content": "Inhibition of mitogenic stimulation of mouse lymphocytes by anti-mouse immunoglobulin antibodies. I. Mode of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214706"} {"pmid": "4214707", "title": "IgD and IgM on the membrane of lymphoid cells in macroglobulinemia. Evidence for identity of membrane IgD and IgM antibody activity in a case with anti-IgG receptors.", "content": "IgD and IgM on the membrane of lymphoid cells in macroglobulinemia. Evidence for identity of membrane IgD and IgM antibody activity in a case with anti-IgG receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214707"} {"pmid": "4214708", "title": "The in vivo effects of concanavalin A on the cellular immune response in BALB-c mice. Inhibition of the delayed hypersensitivity reaction to tuberculin.", "content": "The in vivo effects of concanavalin A on the cellular immune response in BALB-c mice. Inhibition of the delayed hypersensitivity reaction to tuberculin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214708"} {"pmid": "4214710", "title": "Ontogeny and localization of gamma-crystallins in Rana temporaria, Ambystoma mexicanum and Pleurodeles waltlii normal lens development.", "content": "Ontogeny and localization of gamma-crystallins in Rana temporaria, Ambystoma mexicanum and Pleurodeles waltlii normal lens development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214710"} {"pmid": "4214709", "title": "Membrane 32P-phospholipid labeling in early developing toad embryos.", "content": "Membrane 32P-phospholipid labeling in early developing toad embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214709"} {"pmid": "4214712", "title": "Trypanosoma cruzi: morphogenesis in diffusion chambers in the mouse peritoneal cavity and attempted stimulation of host immunity.", "content": "Trypanosoma cruzi: morphogenesis in diffusion chambers in the mouse peritoneal cavity and attempted stimulation of host immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214712"} {"pmid": "4214713", "title": "The amino acid sequence and predicted structure of Streptomyces griseus protease A.", "content": "The amino acid sequence and predicted structure of Streptomyces griseus protease A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214713"} {"pmid": "4214711", "title": "Schistosoma mansoni: mechanism of cercarial tail loss and its significance to host penetration.", "content": "Schistosoma mansoni: mechanism of cercarial tail loss and its significance to host penetration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214711"} {"pmid": "4214714", "title": "Biogenic amine specificity of cortical peptide synthesis in monkey brain.", "content": "Biogenic amine specificity of cortical peptide synthesis in monkey brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214714"} {"pmid": "4214715", "title": "Immobilization of ligands for biospecific affinity chromatography via their hydroxyl groups. The cyclohexaamylose-beta-amylase system.", "content": "Immobilization of ligands for biospecific affinity chromatography via their hydroxyl groups. The cyclohexaamylose-beta-amylase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214715"} {"pmid": "4214716", "title": "The correlation between the apparent molecular weight and the enzymic activity of lactose synthetase.", "content": "The correlation between the apparent molecular weight and the enzymic activity of lactose synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214716"} {"pmid": "4214717", "title": "Precipitating antibodies directed against soluble elastin - the basis of a sensitive assay.", "content": "Precipitating antibodies directed against soluble elastin - the basis of a sensitive assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214717"} {"pmid": "4214718", "title": "Glycollate formation and excretion by the purple photosynthetic bacterium Rhodospirillum rubrum.", "content": "Glycollate formation and excretion by the purple photosynthetic bacterium Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214718"} {"pmid": "4214719", "title": "Transformation of organic compounds by microbial enzymes.", "content": "Transformation of organic compounds by microbial enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214719"} {"pmid": "4214720", "title": "The surfactant system of the lung.", "content": "The surfactant system of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214720"} {"pmid": "4214721", "title": "Clinically useful antibiotics obtained by directed chemical modification-lincomycins.", "content": "Clinically useful antibiotics obtained by directed chemical modification-lincomycins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214721"} {"pmid": "4214723", "title": "The synthesis and activity of tyrosinase during development of the frog Rana pipiens.", "content": "The synthesis and activity of tyrosinase during development of the frog Rana pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214723"} {"pmid": "4214724", "title": "Transcriptionally dependent accumulation of tyrosinase polyribosomes during frog embryonic development and its relationship to neural plate induction.", "content": "Transcriptionally dependent accumulation of tyrosinase polyribosomes during frog embryonic development and its relationship to neural plate induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214724"} {"pmid": "4214725", "title": "Esophagoscopy as a source of Pseudomonas aeruginosa sepsis in patients with acute leukemia: the need for sterilization of endoscopes.", "content": "Esophagoscopy as a source of Pseudomonas aeruginosa sepsis in patients with acute leukemia: the need for sterilization of endoscopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214725"} {"pmid": "4214726", "title": "Role of oral intake in maintenance of gut mass and disaccharide activity.", "content": "Role of oral intake in maintenance of gut mass and disaccharide activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214726"} {"pmid": "4214728", "title": "Role of lysosomes in carrageenan-induced cecal ulceration.", "content": "Role of lysosomes in carrageenan-induced cecal ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214728"} {"pmid": "4214727", "title": "Kaposi's sarcoma presenting with diarrhea and protein-losing enteropathy.", "content": "Kaposi's sarcoma presenting with diarrhea and protein-losing enteropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214727"} {"pmid": "4214729", "title": "Adenine nucleotide metabolism in regenerative, atrophic, and necrotizing processes of the liver.", "content": "Adenine nucleotide metabolism in regenerative, atrophic, and necrotizing processes of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214729"} {"pmid": "4214730", "title": "Effect of TSH and long-acting thyroid stimulator on thyroid 131I-metabolism and metamorphosis of the Mexican axolotl (Ambystoma mexicanum).", "content": "Effect of TSH and long-acting thyroid stimulator on thyroid 131I-metabolism and metamorphosis of the Mexican axolotl (Ambystoma mexicanum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214730"} {"pmid": "4214731", "title": "The role of TRH in the neoteny of the Mexican axolotl (Ambystoma mexicanum).", "content": "The role of TRH in the neoteny of the Mexican axolotl (Ambystoma mexicanum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214731"} {"pmid": "4214732", "title": "Effect of glucose on vanillic acid oxidation in Cellulomonas sp.", "content": "Effect of glucose on vanillic acid oxidation in Cellulomonas sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214732"} {"pmid": "4214734", "title": "Changes in the level and character of colostral immunoglobulins during the lactation period in sows.", "content": "Changes in the level and character of colostral immunoglobulins during the lactation period in sows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214734"} {"pmid": "4214733", "title": "D-amino acids in the cell pool of bacteria.", "content": "D-amino acids in the cell pool of bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214733"} {"pmid": "4214735", "title": "Distribution of interindividual distances in patas monkeys and gelada baboons. Species and sex differences.", "content": "Distribution of interindividual distances in patas monkeys and gelada baboons. Species and sex differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214735"} {"pmid": "4214736", "title": "Activity patterns of red colobus (Colobus badius tephrosceles).", "content": "Activity patterns of red colobus (Colobus badius tephrosceles).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214736"} {"pmid": "4214738", "title": "An analysis of subgroup structure and process in a captive squirrel monkey (Saimiri sciureus) colony.", "content": "An analysis of subgroup structure and process in a captive squirrel monkey (Saimiri sciureus) colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214738"} {"pmid": "4214737", "title": "Ecology and population dynamics of Colobus guereza in Ethiopia.", "content": "Ecology and population dynamics of Colobus guereza in Ethiopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214737"} {"pmid": "4214739", "title": "The behavioral repertoire of the squirrel monkey (Saimiri).", "content": "The behavioral repertoire of the squirrel monkey (Saimiri).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214739"} {"pmid": "4214740", "title": "Visual acuity as a function of wavelength in three Catarrhine species.", "content": "Visual acuity as a function of wavelength in three Catarrhine species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214740"} {"pmid": "4214741", "title": "Aflatoxins and sterigmatocystins.", "content": "Aflatoxins and sterigmatocystins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214741"} {"pmid": "4214742", "title": "The antibiotic complex of the verrucarins and roridins.", "content": "The antibiotic complex of the verrucarins and roridins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214742"} {"pmid": "4214743", "title": "Evidence that glyburide-induced diuresis is not mediated by inhibition of ADH.", "content": "Evidence that glyburide-induced diuresis is not mediated by inhibition of ADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214743"} {"pmid": "4214744", "title": "Influence of Ca2 ions on the activity of human liver glutamate dehydrogenase.", "content": "Influence of Ca2 ions on the activity of human liver glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214744"} {"pmid": "4214745", "title": "Purification and some properties of a heat labile serum factor (UP); identity with glycine-rich beta-glycoprotein and properdin factor B.", "content": "Purification and some properties of a heat labile serum factor (UP); identity with glycine-rich beta-glycoprotein and properdin factor B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214745"} {"pmid": "4214748", "title": "A combination of micro-disc electrophoresis with antigen-antibody crossed electrophoresis. Identification and quantitative determination of individual serumproteins.", "content": "A combination of micro-disc electrophoresis with antigen-antibody crossed electrophoresis. Identification and quantitative determination of individual serumproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214748"} {"pmid": "4214753", "title": "The suitability of lipase from Rhizopus arrhizus delemar for analysis of fatty acid distribution in dihexosyl diglycerides, phospholipids and plant sulfolipids.", "content": "The suitability of lipase from Rhizopus arrhizus delemar for analysis of fatty acid distribution in dihexosyl diglycerides, phospholipids and plant sulfolipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214753"} {"pmid": "4214754", "title": "The amino acid sequences of the alpha and beta polypeptide chains of adult hemoglobin of the savannah monkey (Cereopithecus aethiops).", "content": "The amino acid sequences of the alpha and beta polypeptide chains of adult hemoglobin of the savannah monkey (Cereopithecus aethiops).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214754"} {"pmid": "4214755", "title": "The chemical modification of peptide antibiotics. Part II. The relative roles of ethanolamine and indole groupings in the biological activity of gramicidin.", "content": "The chemical modification of peptide antibiotics. Part II. The relative roles of ethanolamine and indole groupings in the biological activity of gramicidin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214755"} {"pmid": "4214756", "title": "Reassociation of IgM subunits in the presence and absence of J chain.", "content": "Reassociation of IgM subunits in the presence and absence of J chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214756"} {"pmid": "4214757", "title": "Carcinoembryonic antigen (CEA): activity of meconium and normal colon extracts.", "content": "Carcinoembryonic antigen (CEA): activity of meconium and normal colon extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214757"} {"pmid": "4214759", "title": "IgA as a blocking factor in human malignant melanoma.", "content": "IgA as a blocking factor in human malignant melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214759"} {"pmid": "4214758", "title": "Cryoproteins in acute serum sickness: correlations between antigen cryoprecipitation, immune complexes and immune elimination in acute experimental serum sickness.", "content": "Cryoproteins in acute serum sickness: correlations between antigen cryoprecipitation, immune complexes and immune elimination in acute experimental serum sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214758"} {"pmid": "4214760", "title": "Immunosuppressive activity of mouse amniotic fluid.", "content": "Immunosuppressive activity of mouse amniotic fluid. Immunosuppressive activity of mouse amniotic fluid was investigated. Swiss mice were treated from birth through young adulthood with intraperitoneal injections of homologous mouse amniotic fluid. A marked suppression of the primary splenic plaque-forming cells antibody response to sheep red blood cells was demonstrated. A pronounced suppressive effect by amniotic fluid was noted on the gamma A and gamma G plaque-forming cells, with variable degrees of immunosuppression observed on the gamma M response. It is postulated that the immunosuppressive effect of amniotic fluid may be related to its alpha-fetoprotein content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214760"} {"pmid": "4214761", "title": "Bypass-activation of the complement system starting with C3. I. Generation and function of an enzyme from a factor of guinea-pig serum and cobra venom.", "content": "Bypass-activation of the complement system starting with C3. I. Generation and function of an enzyme from a factor of guinea-pig serum and cobra venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214761"} {"pmid": "4214762", "title": "Intestinal secretion of immunoglobulins in the preruminant calf.", "content": "Intestinal secretion of immunoglobulins in the preruminant calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214762"} {"pmid": "4214763", "title": "The influence of preparturient intramammary vaccination on immunoglobulin levels in bovine mammary secretions.", "content": "The influence of preparturient intramammary vaccination on immunoglobulin levels in bovine mammary secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214763"} {"pmid": "4214765", "title": "Angiokeratoma.", "content": "Angiokeratoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214765"} {"pmid": "4214766", "title": "Studies on Pseudomonas biomass obtained from petroleum fractions.", "content": "Studies on Pseudomonas biomass obtained from petroleum fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214766"} {"pmid": "4214764", "title": "IgG heavy chain sub-classes in mixed cryoglobulins.", "content": "IgG heavy chain sub-classes in mixed cryoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214764"} {"pmid": "4214767", "title": "Mental retardation in children. III. Tay-Sachs disease and infantile lipid storage disorders with visceral involvement.", "content": "Mental retardation in children. III. Tay-Sachs disease and infantile lipid storage disorders with visceral involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214767"} {"pmid": "4214768", "title": "Local antibody production in experimental pyelonephritis: amount, avidity, and immunoglobulin class.", "content": "Local antibody production in experimental pyelonephritis: amount, avidity, and immunoglobulin class. LOCAL ANTIBODY FORMATION IN INFECTED RABBIT KIDNEYS WAS STUDIED WITH THREE TECHNIQUES: the ammonium sulfate precipitation technique, the enzyme-linked immunosorbent assay, and by binding of newly synthesized (14)C-labeled antibodies to heat-killed bacteria. Local antibody was detected by day 11 of infection with all three techniques, and a significant correlation was found in titers by all three methods. In these studies, antibody synthesized early was in IgG and IgA class, whereas IgM antibodies appeared later (day 20) in the antibody response. No maturation of avidity of local antibody was noted with time. Since it was necessary to use different animals at each test occasion, individual differences in avidity could account for failure to note an increase in avidity with time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214768"} {"pmid": "4214769", "title": "Virulence and the role of iron in Pseudomonas aeruginosa infection.", "content": "Virulence and the role of iron in Pseudomonas aeruginosa infection. The virulence of Pseudomonas aeruginosa can be enhanced by passage in mice or rabbits. Enhanced virulence has some specificity for the host in which the passage is done. Experimental infection in the peritoneal cavity of cannulated rabbits has shown that the injection of iron compounds can lead to a rapid and fatal growth of an otherwise nonlethal dose of bacteria. In vitro the unsaturated iron-binding proteins present in the peritoneal fluid can halve the growth rate of P. aeruginosa. The restricted rate of growth is restored to normal if the iron-binding proteins are saturated with iron. Exactly the same results are achieved with purified transferrin. Both fatal and nonfatal infections with P. aeruginosa cause a sharp fall in the percentage of saturation with Fe of the plasma and peritoneal fluid. In both normal and infected animals the peritoneal fluid is invariably less saturated than the plasma. Specific antiserum not only protects against death but also against the fall in iron saturation of the plasma and peritoneal fluid. In both fatal and nonfatal infections a high proportion of viable bacteria are unphagocytized in the peritoneal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214769"} {"pmid": "4214770", "title": "Local antibody production against the murine toxin of Yersinia pestis in a golf ball-induced granuloma.", "content": "Local antibody production against the murine toxin of Yersinia pestis in a golf ball-induced granuloma. The method of Garra and Baygorria, for localized antibody production, has been adapted for obtaining high-titered and monospecific antibodies against the murine toxin of Yersinia pestis. A hollow, perforated plastic golf ball surgically implanted under the skin of rabbits induced the formation of a granuloma. When the murine toxin of Y. pestis was injected directly into the granulomatous cavity, an increased amount of antibody was found in the granuloma fluid as compared with serum or with serum antibody obtained by conventional immunization. The granuloma antibody consisted mainly of immunoglobulin G, probably produced locally by lymphoid cells of the granuloma. The immune granuloma fluid and the granuloma tissue were rich in plasma cells and lymphocytes. The chemical composition of the granuloma fluid indicated that it was a transudate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214770"} {"pmid": "4214772", "title": "Growth inhibition among strains of Neisseria gonorrhoeae due to production of inhibitory free fatty acids and lysophosphatidylethanolamine: absence of bacteriocins.", "content": "Growth inhibition among strains of Neisseria gonorrhoeae due to production of inhibitory free fatty acids and lysophosphatidylethanolamine: absence of bacteriocins. Each of 50 tested strains of Neisseria gonorrhoeae produced growth-inhibitory substances that were active against most strains of gonococci or meningococci, but not against species other than the Neisseria. There were quantitative differences among different strains in production of the inhibitor and sensitivity to it, but not of sufficient magnitude to permit routine strain typing. The inhibitor was associated with the cell pellet (crude cell envelope) and was not inducible with mitomycin C. Inhibitory activity was thermostable and resisted alkali and proteolytic enzymes. The inhibitor was quantitatively recovered from whole cells by chloroform-methanol extraction. Separation of total gonococcal lipids by silica gel chromatography revealed inhibitory activity in both the free fatty acid and the phospholipid fractions. The major phospholipid, phosphatidylethanolamine, had no inhibitory activity, but monoacyl phosphatidylethanolamine, a minor phospholipid, was quite inhibitory. It is likely that the \"bacteriocin\" of N. gonorrhoeae strains results from the degradation of phosphatidylethanolamine to inhibitory long-chain free fatty acids and monoacyl phosphatidylethanolamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214772"} {"pmid": "4214771", "title": "Lipid metabolism of monkey kidney cells (LLC-MK-2) infected with Chlamydia trachomatis strain lymphogranuloma venereum.", "content": "Lipid metabolism of monkey kidney cells (LLC-MK-2) infected with Chlamydia trachomatis strain lymphogranuloma venereum. Lipid metabolism of monkey kidney (LLC-MK-2) cells and cells infected with a Chlamydia trachomatis strain lymphogranuloma venereum (LGV) was studied. The protein-to-lipid ratio of normal MK-2 cells was found to increase linearly over a 60-h period of incubation. The protein-to-lipid ratio of the infected cells was similar to that in normal cells until 36 h after infection, when a plateau in the ratio was observed. Lipid synthesis of the infected cells was found to be inhibited after 48 h of infection. Turnover of host lipids did not appear to be markedly altered by infection with LGV over a 48-h period of incubation. An anteiso branched chain of 15:0 fatty acid was found in infected cells but not in normal cells. The appearance of this fatty acid, correlated with a rise in the infectivity of LGV, suggests that synthesis of specific lipids was associated with the infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214771"} {"pmid": "4214773", "title": "Inflammatory lymphocyte in cell-mediated antibacterial immunity: factors governing the accumulation of mediator T cells in peritoneal exudates.", "content": "Inflammatory lymphocyte in cell-mediated antibacterial immunity: factors governing the accumulation of mediator T cells in peritoneal exudates. The lymphocytes which mediate immunity to infection with Listeria monocytogenes in the mouse accumulated in casein-induced peritoneal exudates. They were T cells, as evidenced by their susceptibility to anti-theta serum, but some were also destroyed by anti-immunoglobulin serum. For a given number of cells, exudate cells were at least six times more efficient than spleen cells in protecting normal recipients against lethal challenge. The extent to which mediator cells accumulated in exudates was found to be governed by the level of their production in responding lymphoid tissue and by the time available for them to migrate into an exudate. An intraperitoneal injection of casein at any stage of infection resulted in a progressive accumulation of mediator cells that continued for 3 days. The accumulation was not caused by continuous entry of cells during the whole of this period, but resulted from division of a limited number of cells that entered during the first 24 h. Accumulation of mediator cells in an exudate was associated with the conversion of a population of dividing cells into a population of nondividing T cells with a relatively short life-span.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214773"} {"pmid": "4214774", "title": "Inhibition of Pseudomonas aeruginosa by hyperbaric oxygen: interaction with mouse peritoneal exudate cells.", "content": "Inhibition of Pseudomonas aeruginosa by hyperbaric oxygen: interaction with mouse peritoneal exudate cells. High-pressure oxygen (HPO) therapy for Pseudomonas aeruginosa infections of burn wounds has not been as effective as in vitro studies predicted. Mitigation of HPO toxicity for P. aeruginosa by nutrients present at the burn site could explain the lack of in vivo success. Alternatively, HPO-induced depression of host defense mechanisms could negate beneficial effects arising from HPOs known toxicity for P. aeruginosa. Accordingly, mouse peritoneal exudate cells (PEC), preincubated for 24 h in 1 atm of air-CO(2), were used to study the in vitro effects of HPO or air-CO(2) on phagocytosis of P. aeruginosa or sheep erythrocytes (SRBC). Subsequent 2-h exposures of PEC to increasing numbers of bacteria, in an air-CO(2) atmosphere, decreased the percentage of bacteria cleared as well as PEC viability. Similar exposures of PEC to bacteria in an HPO atmosphere prevented the loss of PEC viability and increased bacterial clearance. In control experiments, increasing the number of SRBC relative to PEC decreased the percentage of SRBC cleared without decreasing PEC viability, as determined under air-CO(2); short (2 h) exposure to HPO did not affect SRBC clearance. Microscopic examination of PEC indicated that a 24-h preincubation in HPO decreased the percentage of PEC which could ingest SRBC during subsequent experimental exposures (2 h) to air-CO(2) or HPO. These data suggest that short periods of exposure to HPO promote the ability of PEC to clear pseudomonads by adversely affecting the bacteria. This in turn prevents a pseudomonad-induced depression of PEC viability and function. In contrast, prolonged HPO exposure may be detrimental to phagocytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214774"} {"pmid": "4214775", "title": "Protein fraction with immunogenic potential and low toxicity isolated from the cell wall of Neisseria meningitidis group B.", "content": "Protein fraction with immunogenic potential and low toxicity isolated from the cell wall of Neisseria meningitidis group B. Several fractions were extracted from the cell envelope (CE) of Neisseria meningitidis group B and characterized with regard to their morphology, antigenicity, protein composition, and toxicity. Whole bacterial cells were suspended in a medium of low ionic strength and disrupted in a French pressure cell. The crude CE thus obtained were separated into cell membrane (CM) enriched and cell wall (CW) enriched fractions on sucrose density gradients. In addition, CM and CW fractions were separated from CE on the basis of differential solubility in the nonionic detergent, Triton X-100. The Triton-insoluble fraction, containing primarily CW components, was further treated with a mixture of Triton and ethylenediaminetetraacetic acid, which was shown to remove additional protein and most of the lipopolysaccharide. Electron microscope examination of the various fractions revealed typical unit membrane structures in the case of CM, or large, open segments in the case of CW. The Triton-insoluble and especially the Triton-ethylenediaminetetraacetic acid-insoluble fractions consisted of small vesicular structures. All fractions, except the Triton-soluble fraction, when assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, were shown to contain one major protein component accounting for more than 50% of the total. Sera from rabbits immunized with the various fractions formed precipitin lines in immunodiffusion tests against the homologous and some of the heterologous fractions. High-titer bactericidal antibodies were also demonstrated in these sera when tested against the homologous strains. Toxicity studies in rats sensitized with lead acetate indicate that the level of contamination of Triton-insoluble/Triton-ethylenediaminetetraacetic acid-insoluble fractions with lipopolysaccharide was significantly smaller than that of the other fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214775"} {"pmid": "4214777", "title": "Studies on gonococcus infection. VI. Electron microscopic study on in vitro phagocytosis of gonococci by human leukocytes.", "content": "Studies on gonococcus infection. VI. Electron microscopic study on in vitro phagocytosis of gonococci by human leukocytes. The ingestion of Neisseria gonorrhoeae by isolated human leukocytes in vitro has been studied by electron microscopy. Use of the modified critical-point drying method allows clear visualization of progressive ingestion of both pilated and nonpilated gonococci by leukocytes. Incomplete ingestion of pilated gonococci with protrusion of tangled masses of pili from sites of phagocytosis are also found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214777"} {"pmid": "4214776", "title": "Studies on gonococcus infection. V. Observations on in vitro interactions of gonococci and human neutrophils.", "content": "Studies on gonococcus infection. V. Observations on in vitro interactions of gonococci and human neutrophils. The association of in vitro human leukocytes with pilated, type 2 Neisseria gonorrhoeae exceeds that for nonpilated, type 4 organisms but is less than that for nonpilated, type 4(*) gonococci. The two nonpilated forms of gonococci (types 4 and 4(*)) attach to tissue culture cells to a much lesser extent than do pilated, type 2 organisms of the same strain. Trypsin treatment of either pilated (type 2) or nonpilated (type 4(*)) gonococci markedly reduces the attachment-ingestion of these organisms with leukocytes, but the same trypsin treatment does not depilate the type 2 organisms nor visibly alter the morphology of their pili. Similar reductions in association with leukocytes are found if the gonococci are pretreated with chymotrypsin, heat, or glutaraldehyde. High levels of association between gonococci and leukocytes are reestablished if the trypsin or chymotrypsin-treated organisms are reincubated in protease-free medium. These data suggest that interactions between gonococci and human neutrophils are mediated through surface characteristics of the bacteria, different from those which influence attachment of the organisms to tissue culture cells. In the latter instance, pili appear to positively influence gonococcal attachment, whereas in the former a nonpilus bacterial cell wall nonpilus protein is probably the major determiner in the interaction between leukocytes and gonococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214776"} {"pmid": "4214778", "title": "Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae.", "content": "Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae. Five of six independent gonococcal isolates have been found to harbor a plasmid pool of covalently closed-circular deoxyribonucleic acid about 2.4 x 10(6) daltons in size. The plasmid species were 0.5-mol fraction of guanine plus cytosine and comprised 6 to 8% of the total gonococcal deoxyribonucleic acid equivalent, to approximately 24 to 32 copies per cell. There was no apparent correlation between the presence of these plasmid species and the in vitro clonal variation of gonococci associated with the loss of pili.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214778"} {"pmid": "4214779", "title": "Synergistic action of cord factor and mycobacterial sulfatides on mitochondria.", "content": "Synergistic action of cord factor and mycobacterial sulfatides on mitochondria. The mechanism of a synergistic toxicity of 6,6'-dimycoloyl-alpha,alpha'-d-trehalose (cord factor) and 2,3,6,6'-tetraacyl-alpha,alpha'-d-trehalose 2'-sulfate (sulfolipid I) for mice was studied. Sulfolipid I was entirely nontoxic, but it markedly accelerated the lethal toxicity of cord factor for mice. In vivo, sulfolipid I affected neither respiration nor accompanying phosphorylation of mouse liver mitochondria, whereas in vitro, it induced a swelling and disruption of mitochondrial membranes and strongly inhibited mitochondrial oxidative phosphorylation. The effect of sulfolipid I on mitochondrial structure and function in vitro was neutralized by bovine serum albumin and various animal sera, whereas that of cord factor and cord factor plus sulfolipid I was not prevented by bovine serum albumin. The simultaneous injection of cord factor and sulfolipid I caused an intensive fragmentation of mitochondria and a marked decrease in respiratory and phosphorylative activity in mitochondria. These data indicate that sulfolipid I can achieve an effective attack on mitochondria in combination with cord factor in vivo and induces heavier damage in mitochondrial structure and function than that produced by cord factor alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214779"} {"pmid": "4214781", "title": "Purification and some properties of progenitor toxins of Clostridium botulinum type B.", "content": "Purification and some properties of progenitor toxins of Clostridium botulinum type B. Purification of progenitor toxin of Clostridium botulinum type B strain Okra was undertaken by sequential steps of acid precipitation, extraction, ammonium sulfate precipitation, ribonuclease digestion, acid precipitation, protamine treatment, sulphopropyl-Sephadex chromatography, and Sephadex G-200 gel filtration. Two different molecular-sized toxins, named large (L) and medium (M) toxins, were obtained. L toxin was centrifugally homogeneous but electrophoretically heterogeneous. It contained 2.5 x 10(8) to 3.0 x 10(8) mean lethal doses per mg of nitrogen, and its sedimentation constant was 16S. M toxin was centrifugally and electrophoretically homogeneous. It contained 5.5 x 10(8) to 6.0 x 10(8) mean lethal doses per mg of nitrogen, and its sedimentation constant was 12S. The presence of both L and M toxins in spent culture was demonstrated. It seems justified, therefore, to call both progenitor toxins. Both consisted of toxic and nontoxic components. The toxic components of L and M toxins appeared to be identical with each other. The nontoxic component of L toxin was 12S and possessed a hemagglutinin activity of about 0.5% that of type A crystalline toxin; that of M toxin was 7S and possessed no hemagglutinin activity. They were antigenically related but not identical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214781"} {"pmid": "4214780", "title": "Strain virulence and the lysosomal response in macrophages infected with Mycobacterium tuberculosis.", "content": "Strain virulence and the lysosomal response in macrophages infected with Mycobacterium tuberculosis. Strains H37Ra and H37Rv, attenuated and virulent variants, respectively, of the original human strain H37 of Mycobacterium tuberculosis, were used to infect cultures of mouse peritoneal macrophages. Bacterial viability of each strain was assessed over a 2-week period, and the cellular response to H37Ra during the first week was observed using electron microscopy. Prelabeling of secondary lysosomes with ferritin was used to facilitate the estimation of fusion of the lysosomes with phagosomes containing the bacteria. Streptomycin was excluded from the medium of cell cultures infected with H37Ra. The intracellular viability of strain H37Rv (in the presence of streptomycin) showed a lag during the first week after infection and then rose progressively to a mean figure seven times the starting level. In contrast, the viability of strain H37Ra declined, on the average, to one-fifth of the starting level during the first week; moreover, this decline occurred in the absence of antibiotics. In the second week a variable rise in the viable count took place, usually regaining the starting level. Electron microscopy of macrophages infected with H37Ra revealed a higher proportion of \"damaged\" bacteria 5 days after infection than at 1 day, in keeping with the decline in viability. Phagosomes containing these \"damaged\" (and presumed dead) organisms showed virtually universal fusion with prelabeled lysosomes. Phagosomes containing \"intact\" bacteria of this strain showed a prevalence of fusion varying from 38 to 56%, somewhat higher than the level previously reported for \"intact\" organisms of H37Rv. Nevertheless, the lysosome-phagosome fusion response to \"intact\" H37Ra was still far less extensive than that observed previously towards \"intact\" M. lepraemurium (around 90%). In conclusion, a difference between the macrophage lysosome-phagosome fusion response towards viable organisms of strain H37Ra and to the virulent strain H37Rv was observed, but was not pronounced, and the present findings are in keeping with the increasingly held view that H37Ra should be regarded as a low-virulence or attenuated strain rather than truly avirulent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214780"} {"pmid": "4214782", "title": "Cellular immune activity of a galactomannan-protein complex from mycelia of Histoplasma capsulatum.", "content": "Cellular immune activity of a galactomannan-protein complex from mycelia of Histoplasma capsulatum. A galactomannan-protein complex was extracted from defatted mycelium of Histoplasma capsulatum with 0.25 N alkali at 25 C. It accounted for 7.5% of the cell dry weight in nondialyzable form and had a galactose-mannose ratio of 2:5. The complex containing 68% protein was separated into polysaccharide and glycoprotein components by ion-exchange chromatography. The galactomannan formed a single precipitate in immunodiffusion, sharing a common antigen with the glycoprotein which contained two precipitating antigens. The glycoprotein elicited delayed-type hypersensitivity in guinea pigs as measured by skin-test and macrophage migration inhibitory factor assay, with 5 mug resulting in 86% specific inhibition. The galactomannan was skin-test negative, but 10 mug resulted in 80% specific inhibition of migration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214782"} {"pmid": "4214783", "title": "Role of interferon in six cell lines persistently infected with rubella virus.", "content": "Role of interferon in six cell lines persistently infected with rubella virus. Presistent infections with rubella virus were established in baby hamster kidney, BSC-1, HeLa, RK-13, rabbit embryo chondrocyte, and Vero cell lines. All of the cultures except Vero continually produced rubella virus and interferon to which the virus was sensitive. Concurrently, only the Vero cells did not display interference against superinfection with Newcastle disease and vesicular stomatitis viruses. The addition of 1,000 U of exogenous interferon to the cultures cured only the rabbit embryo and Vero cells of the persistent infection. That the interferon is not required for the initiation and maintenance of rubella viral persistence in vitro is implied by the following. (1) Vero cells were persistently infected in the absence of interferon; (2) actinomycin D or cortisone inhibited interferon synthesis but not the rubella viral infection; and (3) cells continuously cultured in the presence of cortisone maintained a viral persistence without interferon synthesis. On the other hand, interferon seems to be responsible for the viral interference; Vero cells infected with rubella virus and cultures inoculated with rubella virus in the presence of actinomycin D or cortisone did not display interference against Newcastle disease or vesicular stomatitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214783"} {"pmid": "4214784", "title": "Growth of typhoid and paratyphoid bacilli in intravenously infected mice.", "content": "Growth of typhoid and paratyphoid bacilli in intravenously infected mice. The in vivo growth of Salmonella paratyphi A, S. paratyphi B, S. paratyphi C, and S. typhi, as well as of an S. typhi-typhimurium hybrid, was studied in three different strains of mice. S. paratyphi A and B and S. typhi demonstrated very little growth potential in any of the intravenously infected mice, even after as many as 20 serial mouse passages. It was noted, however, that small numbers of viable S. paratyphi B and S. typhi persisted in the spleens of infected mice for up to 28 days. Salmonella paratyphi C and the S. typhi-typhimurium hybrid gave rise to progressive systemic infections beginning from very small intravenous inocula. The median lethal doses for the C57B1 strain of mouse were about five organisms. The relevance of these findings with regard to the development of an animal model for studying human typhoid fever vaccines is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214784"} {"pmid": "4214785", "title": "Demonstration of the phenomena of microbial persistence and reversion with bacterial L-forms in human embryonic kidney cells.", "content": "Demonstration of the phenomena of microbial persistence and reversion with bacterial L-forms in human embryonic kidney cells. A series of experiments was undertaken in which human embryonic kidney (HEK) fibroblasts were infected with either relatively stable or stable L-forms of Streptococcus faecalis. The infected cells were maintained by splitting over long periods (1 to 2 months) while samples were withdrawn for culture and electron microscopic studies. Relatively stable S. faecalis L-forms could be cultured from infected cells only during the first week after infection, although L-form-like material was frequently detected at later periods by electron microscopy. HEK cells continued to proliferate and showed no gross histopathology until reversion occurred. At reversion, electron microscopy revealed the presence of intracellular L-forms, transitional variants, and intra- and extracellular bacterial forms. Unlike relatively stable L-forms, stable L-forms were culturable throughout the experimental period. These experiments demonstrate the phenomena of persistence and reversion in vitro. Electron microscopy indicated that the L-forms entered the HEK cells, where they underwent morphological changes. Observations suggested that these altered L-forms (elementary bodies) persisted in the cell until reversion to the parent bacterial form was triggered. Infected cells, when treated with L-form antiserum and stained with fluorescein-conjugated goat anti-rabbit serum, were consistently positive regardless of cultural findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214785"} {"pmid": "4214786", "title": "Proposed reproductive cycle for a relatively stable L-phase variant of Streptococcus faecalis.", "content": "Proposed reproductive cycle for a relatively stable L-phase variant of Streptococcus faecalis. Based on electron microscopic observations, the reproductive cycle of a relatively stable L-phase variant of Streptococcus faecalis was proposed. The small, dense, nonvesiculated L-form is envisioned as the central (core) element. It was seen to divide and bud rapidly. In addition, the dense forms appeared to be capable of growth and development within vesicles of mature mother forms. When these forms were released from the vesicles into the surrounding fluid medium, further growth occurred, resulting in the development of immature and ultimately mature mother forms. Under conditions unfavorable for L-form growth, these dense forms developed first into transitional forms and then into the bacterial form. These dense forms might therefore be considered as undifferentiated \"stem cells' with the capacity to develop along several different routes, depending upon the stimulus received.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214786"} {"pmid": "4214787", "title": "In vitro antilisterial activity of soluble product(s) released from Listeria-immune murine peritoneal macrophages.", "content": "In vitro antilisterial activity of soluble product(s) released from Listeria-immune murine peritoneal macrophages. The importance of macrophages as effector cells in cellular reactions of immunity and hypersensitivity is well established (8). Macrophages activated as a result of specific immunological events exhibit increased microbicidal activity not only for the primary organism used for immunization purposes but also against unrelated intracellular pathogens (7). It is believed that the acquisition of this bactericidal or bacteriostatic activity is conferred on macrophages by materials released during the interaction of specifically immune lymphocytes with the antigen (Fowles et al., 1973; Godal et al., 1971; Jones and Youmans, 1973; Krahenbuhl and Remington, 1971; Mackaness, 1971; Patterson and Youmans, 1970). The antimicrobial activity in these studies refers to the intracellular inhibition and/or killing of the organisms; no attempts were made to assess the effect of activated macrophages on the extracellularly residing organisms. In an earlier study with the pathogenic yeastlike fungus Cryptococcus neoformans, we observed that freshly collected peritoneal macrophages from mice pretreated with a variety of nonspecific agents or from specifically immune mice possessed the capacity to exert anti-cryptococcal effect both on intracellular yeasts as well as those present in the extracellular milieu (Sethi et al., 1971; Sethi and Pelster, in press). Our results suggest that soluble product(s) released from mouse macrophages immune to Listeria monocytogenes can exert antilisterial activity under in vitro conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214787"} {"pmid": "4214788", "title": "The microbial decomposition of dental resins and its importance to the microbial balance of the oral cavity.", "content": "The microbial decomposition of dental resins and its importance to the microbial balance of the oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214788"} {"pmid": "4214789", "title": "Bursal and postbursal cells in chicken: age-dependence of germinal center formation in spleen.", "content": "Bursal and postbursal cells in chicken: age-dependence of germinal center formation in spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214789"} {"pmid": "4214790", "title": "Application of in vitro and in vivo assay techniques in the isolation of rye grass (Lolium perenne) pollen allergens.", "content": "Application of in vitro and in vivo assay techniques in the isolation of rye grass (Lolium perenne) pollen allergens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214790"} {"pmid": "4214794", "title": "The in vivo distribution of 51Cr-labeled Trypanosoma cruzi in mice.", "content": "The in vivo distribution of 51Cr-labeled Trypanosoma cruzi in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214794"} {"pmid": "4214795", "title": "Autoimmunity in trypanosome infections. II. Anti-fibrin-fibrinogen (anti-F) autoantibody in Trypanosoma (Trypanozoon) brucei infections of the rabbit.", "content": "Autoimmunity in trypanosome infections. II. Anti-fibrin-fibrinogen (anti-F) autoantibody in Trypanosoma (Trypanozoon) brucei infections of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214795"} {"pmid": "4214797", "title": "Host dietary changes and the hindgut fauna of cockroaches.", "content": "Host dietary changes and the hindgut fauna of cockroaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214797"} {"pmid": "4214798", "title": "The production of bismuth-204 for medical use.", "content": "The production of bismuth-204 for medical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214798"} {"pmid": "4214801", "title": "Ossifying fibroma, a neoplastic entity.", "content": "Ossifying fibroma, a neoplastic entity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214801"} {"pmid": "4214800", "title": "Calcium and high molecular weight protein aggregates in bovine and human lens.", "content": "Calcium and high molecular weight protein aggregates in bovine and human lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214800"} {"pmid": "4214799", "title": "Cell-surface receptors of normal, regenerating, and cultured corneal epithelial and endothelial cells.", "content": "Cell-surface receptors of normal, regenerating, and cultured corneal epithelial and endothelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214799"} {"pmid": "4214793", "title": "New methods for surface ultrastructure: Comparative studies of scanning electron microscopy, transmission electron microscopy and replica method.", "content": "New methods for surface ultrastructure: Comparative studies of scanning electron microscopy, transmission electron microscopy and replica method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214793"} {"pmid": "4214803", "title": "Host factors in post-operative infections due to Pseudomonas aeruginosa.", "content": "Host factors in post-operative infections due to Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214803"} {"pmid": "4214792", "title": "Serum histaminase in leprosy.", "content": "Serum histaminase in leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214792"} {"pmid": "4214805", "title": "Procedures for clinical management of pinnipeds.", "content": "Procedures for clinical management of pinnipeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214805"} {"pmid": "4214806", "title": "Extraction and analysis of Aroclor 1254 components in blood.", "content": "Extraction and analysis of Aroclor 1254 components in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214806"} {"pmid": "4214804", "title": "The use of quantiatative cytochemical analyses in rapid prenatal detection and somatic cell genetic studies of metabolic diseases.", "content": "The use of quantiatative cytochemical analyses in rapid prenatal detection and somatic cell genetic studies of metabolic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214804"} {"pmid": "4214807", "title": "Applications of nuclear magnetic resonance spectroscopy to antibiotics. I. Specific identification of penicillins and cephalosporins.", "content": "Applications of nuclear magnetic resonance spectroscopy to antibiotics. I. Specific identification of penicillins and cephalosporins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214807"} {"pmid": "4214808", "title": "Gas-liquid chromatographic determination of ethylenediaminetetraacetic acid in pickled vegetables.", "content": "Gas-liquid chromatographic determination of ethylenediaminetetraacetic acid in pickled vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214808"} {"pmid": "4214809", "title": "Tobacco sensitivity in the allergic population. A specific allergic entity.", "content": "Tobacco sensitivity in the allergic population. A specific allergic entity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214809"} {"pmid": "4214810", "title": "Immune responses to chemically modified bacterial alpha-amylase.", "content": "Immune responses to chemically modified bacterial alpha-amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214810"} {"pmid": "4214811", "title": "Immunochemical comparison of myosins from chicken cardiac, fast white, slow red, and smooth muscle.", "content": "Immunochemical comparison of myosins from chicken cardiac, fast white, slow red, and smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214811"} {"pmid": "4214812", "title": "Further studies on the stability of sporulation messenger ribonucleic acid in Bacillus subtilis.", "content": "Further studies on the stability of sporulation messenger ribonucleic acid in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214812"} {"pmid": "4214813", "title": "GM1 ganglioside beta-galactosidase. A. Purification and studies of the enzyme from human liver.", "content": "GM1 ganglioside beta-galactosidase. A. Purification and studies of the enzyme from human liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214813"} {"pmid": "4214814", "title": "Variations in the quaternary structure of three lactic acid bacteria aldolases. Evidence for the existence of a class I and class II aldolase in Lactobacillus casei.", "content": "Variations in the quaternary structure of three lactic acid bacteria aldolases. Evidence for the existence of a class I and class II aldolase in Lactobacillus casei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214814"} {"pmid": "4214815", "title": "The conformation of thermolysin.", "content": "The conformation of thermolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214815"} {"pmid": "4214816", "title": "Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. I. Studies on factors affecting the toxin and antitoxin titration.", "content": "Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. I. Studies on factors affecting the toxin and antitoxin titration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214816"} {"pmid": "4214817", "title": "Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. II. Comparison with the rabbit skin method and practical application for seroepidemiological studies.", "content": "Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. II. Comparison with the rabbit skin method and practical application for seroepidemiological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214817"} {"pmid": "4214818", "title": "The protective effect of Pseudomonas culture filtrates against experimental infection in mice.", "content": "The protective effect of Pseudomonas culture filtrates against experimental infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214818"} {"pmid": "4214819", "title": "Standardization and quality control of Leishmania tropica vaccine.", "content": "Standardization and quality control of Leishmania tropica vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214819"} {"pmid": "4214820", "title": "A wear resistant material for total joint replacement--tissue biocompatibility of an ultra-high molecular weight (UHMW) polyethylene-graphite composite.", "content": "A wear resistant material for total joint replacement--tissue biocompatibility of an ultra-high molecular weight (UHMW) polyethylene-graphite composite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214820"} {"pmid": "4214821", "title": "Determination of rates of DNA synthesis in cultured mammalian cell populations.", "content": "Determination of rates of DNA synthesis in cultured mammalian cell populations. In cultures of a murine mastocytoma, endogenous synthesis of thymidine phosphates, as determined by the incorporation of [(3)H]deoxyuridine into DNA, was reduced within 15 min to less than 3% of control values by the addition of amethopterin (10 microM) in combination with hypoxanthine and glycine. If [(3)H]thymidine and unlabeled thymidine were added simultaneously with amethopterin, the increase with time of radioactivity in cellular DNA was linear at least between 30 and 90 min, while radioactivity in the acid-soluble nucleotide fraction remained constant during this time interval, indicating that intracellular thymidine nucleotides had the same specific activity as exogenously supplied [(3)H]thymidine. This permitted calculation of the amount of thymidine incorporated per hour into DNA of 10(6) cells. In conjunction with the base composition of mouse DNA, these results were used to calculate rates of DNA synthesis. Cell proliferation rate, cell cycle time, and the duration of the S period were not affected to any appreciable extent by the addition of amethopterin and thymidine. Rates of DNA synthesis, as derived from thymidine incorporation rates, were in good agreement with those derived from the measured mean DNA content of exponentially multiplying cells and rates of cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214821"} {"pmid": "4214822", "title": "Action of cytochalasin D on cells of established lines. II. Cortex and microfilaments.", "content": "Action of cytochalasin D on cells of established lines. II. Cortex and microfilaments. Cells in culture exposed to cytochalasin D (CD) rapidly undergo a long-sustained tonic contraction. Coincident with this contracture the thin microfilaments of the cortex become compacted into feltlike masses. The ravelled filaments of these masses remain actinlike and bind heavy meromyosin; they are not disrupted or disaggregated, but rather, appear to represent a contracted state of the microfilament apparatus of the cell cortex. On continued exposure to CD, 'myoid' bundles, containing thick, dense filaments, and larger fusiform or ribbonlike, putatively myosinoid, aggregates may appear. These appearances are interpreted as consequences of a state of hypercontraction without relaxation induced by CD. They do not occur in CD-treated cells prevented from contracting by inhibitors of energy metabolism, and are readily reversible on withdrawal of CD. Extensive ordered arrays of thin microfilaments develop in cells which are reextending during early recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214822"} {"pmid": "4214823", "title": "Microtubule arms and cytoplasmic streaming and microtubule bending and stretching of intertubule links in the feeding tentacle of the suctorian ciliate Tokophrya.", "content": "Microtubule arms and cytoplasmic streaming and microtubule bending and stretching of intertubule links in the feeding tentacle of the suctorian ciliate Tokophrya. Microtubules attached to the pellicle at the tips of tentacles pivot through about 140 degrees on these attachments, splay apart, and bend along their longitudinal axes when feeding occurs. The tubules could be bending in response to pellicular contractions; active bending, sliding, or contraction of the tubules may not be involved. Intertubule links apparently prevent tubules from splaying apart at certain levels. These links are probably under tension during feeding. They stretch; they sometimes become half as thick and eight times as long as they are before feeding. Often, tubules joined together by these links also change in shape; they become slightly flattened and elliptical in cross section. Cytoplasm from the ciliate Tetrahymena is drawn down a feeding tentacle inside an invagination of the Tokophrya cell membrane from the tentacle tip. The positions of arm-bearing microtubules around such invaginations indicate that arms are involved in moving invaginations along. The edges of the perforated Tetrahymena cell membrane are \"sealed\" to the cell membrane of Tokophrya around each feeding tentacle tip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214823"} {"pmid": "4214824", "title": "Ciliary membrane differentiations in Tetrahymena pyriformis. Tetrahymena has four types of cilia.", "content": "Ciliary membrane differentiations in Tetrahymena pyriformis. Tetrahymena has four types of cilia. We have examined thin sections and replicas of freeze-fractured cilia of Tetrahymena pyriformis. The ciliary necklace located at the base of all freeze-fractured oral and somatic cilia has been studied in thin sections. Since electron-dense linkers have been found to connect both microtubule doublets and triplets to the ciliary membrane at the level of the necklace, the linkers and the associated necklace seem to be related to the transition region between the doublets and triplets of a cilium. Plaque structures, consisting of small rectangular patches of particles located distal to the ciliary necklace, are found in strain GL, but are absent in other strains examined in this study. In freeze-cleaved material, additional structural differentiations are observed in the distal region of the ciliary membranes of somatic and oral cilia. Somatic cilia contain many randomly distributed particles within their membrane. Oral cilia can be divided into three categories on the basis of the morphology of their freeze-fractured membranes: (a) undifferentiated cilia with very few randomly distributed particles: (b) cilia with particles arranged in parallel longitudinal rows spaced at intervals of 810-1080 A that are located on one side of the cilium; and (c) cilia with patches of particles arranged in short rows oriented obliquely to the main axis of the cilium. The latter particles, found on one side of the cilium, seem to serve as attachment sites for bristles 375-750 A long and 100 A wide which extend into the surrounding medium. The particles with bristles are located at the tips of cilia in the outermost membranelle and may be used to detect food particles and/or to modify currents in the oral region so that food particles are propelled more efficiently into the buccal cavity. Examination of thin-sectioned material indicates that the particles in oral cilia which form the longitudinal rows could be linked to microtubule doublets. Linkage between microtubule doublets and adjacent membrane areas on one side of the cilium could modify the form of ciliary beat by restricting the sliding of the microtubules. It is suggested that membrane-microtubule interactions may form the basis for the various forms of ciliary beat observed in different organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214824"} {"pmid": "4214825", "title": "Electron microscope evidence of calcium-induced exocytosis in mast cells treated with 48-80 or the ionophores A-23187 and X-537A.", "content": "Electron microscope evidence of calcium-induced exocytosis in mast cells treated with 48-80 or the ionophores A-23187 and X-537A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214825"} {"pmid": "4214826", "title": "The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis.", "content": "The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214826"} {"pmid": "4214830", "title": "Chlorobiphenylols. Thin-layer chromatography and colour reactions of some hydroxylated chlorobiphenyls.", "content": "Chlorobiphenylols. Thin-layer chromatography and colour reactions of some hydroxylated chlorobiphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214830"} {"pmid": "4214831", "title": "Metabolism of 17 alpha-ethinylestradiol by human liver microsomes in vitro: aromatic hydroxylation and irreversible protein binding of metabolites.", "content": "Metabolism of 17 alpha-ethinylestradiol by human liver microsomes in vitro: aromatic hydroxylation and irreversible protein binding of metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214831"} {"pmid": "4214832", "title": "Radioimmunoassay for human antithyroglobulin antibodies. II. Determination of antigen-binding capacity.", "content": "Radioimmunoassay for human antithyroglobulin antibodies. II. Determination of antigen-binding capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214832"} {"pmid": "4214833", "title": "Heterogeneity of circulating growth hormone in acromegaly.", "content": "Heterogeneity of circulating growth hormone in acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214833"} {"pmid": "4214835", "title": "Skeletal metabolism and body composition in Cushing's syndrome.", "content": "Skeletal metabolism and body composition in Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214835"} {"pmid": "4214834", "title": "Evidence for a direct effect of thyrotropin-releasing hormone (TRH) on prolactin release in humans.", "content": "Evidence for a direct effect of thyrotropin-releasing hormone (TRH) on prolactin release in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214834"} {"pmid": "4214837", "title": "Hyperresponse to thyrotropin-releasing hormone accompanying small decreases in serum thyroid hormone concentrations.", "content": "Hyperresponse to thyrotropin-releasing hormone accompanying small decreases in serum thyroid hormone concentrations. To determine whether pituitary thyrotropin (TSH) responsiveness to thyrotropin-releasing hormone (TRH) is enhanced by small decreases in serum thyroxine (T4) and triiodothyronine (T3), 12 euthyroid volunteers were given 190 mg iodide po daily for 10 days to inhibit T4 and T3 release from the thyroid. Basal serum T4, T3, and TSH concentrations and the serum T4 and TSH responses to 400 mug TRH i.v. were assessed before and at the end of iodide administration. Iodide induced small but highly significant decreases in basal serum T4 (8.0+/-1.6 vs. 6.6+/-1.7 mug/100 ml; mean +/- SD) and T3 (128+/-15 vs. 110+/-22 ng/100 ml) and increases in basal serum TSH (1.3+/-0.9 vs. 2.1+/-1.0 muU/ml). During iodide administration, the TSH response to TRH was significantly increased at each of seven time points up to 120 min. The maximum increment in serum TSH after TRH increased from a control mean of 8.8+/-4.1 to a mean of 13.0+/-2.8 muU/ml during iodide administration. As evidence of the inhibitory effect of iodide on hormonal release, the increment in serum T3 at 120 min after TRH was significantly lessened during iodide administration (61+/-42 vs. 33+/-24 ng/100 ml). These findings demonstrate that small acute decreases in serum T4 and T3 concentrations, resulting in values well within the normal range, are associated both with slight increases in basal TSH concentrations and pronounced increases in the TSH response to TRH. These results demonstrate that a marked sensitivity of TSH secretion and responsiveness to TRH is applicable to decreasing, as well as increasing, concentrations of thyroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214837"} {"pmid": "4214836", "title": "Sanfilippo A syndrome: sulfamidase deficiency in cultured skin fibroblasts and liver.", "content": "Sanfilippo A syndrome: sulfamidase deficiency in cultured skin fibroblasts and liver. The Sanfilippo A syndrome is an autosomal recessive mucopolysaccharidosis characterized clinically by severe mental retardation and biochemically by storage in tissue and excretion in urine of excessive amounts of heparan sulfate. Since sulfamide groups are present in heparan sulfate, a sulfamidase deficiency could explain the impaired degradation of this polysaccharide. To investigate the enzymic basis of this disease, assays for sulfamidase were performed. Extracts of cultured fibroblasts and post-mortem liver were prepared by suspension of tissues in acetate: NaCl buffer, pH 4.5, containing Triton X-100 (Rohm and Haas Co., Philadelphia, Pa.), sonication, and centrifugation at 10,000 g. The supernatant fluid was incubated with [(35)S]-N-sulfated heparin. The release of inorganic sulfate after 18 h of incubation was determined by chromatography on Sephadex G-25. The liver and fibroblast extracts of patients with the Sanfilippo A syndrome showed a deficiency of sulfamidase. The quantity of heparan sulfate in fibroblasts derived from patients with Sanfilippo A, Hurler's and Hunter's diseases was found to be 7-10%, while it was about 1.25% of the total glycosaminoglycans in fibroblasts of normal controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214836"} {"pmid": "4214838", "title": "Serum 'uracil plus uridine' levels in normal subjects and their possible significance.", "content": "Serum 'uracil plus uridine' levels in normal subjects and their possible significance. A microbiological method for the assay of uracil is described. The growth of the test organism is supported by uracil and also by uridine but not by uridylic acid. The method therefore measures uracil and uridine together. The ;uracil + uridine' level, expressed as uracil, has been measured in blood from 144 normal subjects ranging in age from cord blood to the eighth decade. The mean level of 22 mu mol/l (0.25 mg%) in cord blood decreases to 15 mumol/l (0.17 mg%) in adults over the age of 20. There is no difference between the sexes. Uracil is of interest because (a) it is a constituent base of RNA, (b) it is the precursor of two of the bases thymine and cytosine that enter into the composition of DNA, and (c) under certain circumstances it has mutagenic properties. The last is dependent upon the existence of two tautomeric forms of uracil, the common keto form which pairs normally with adenine and the rare enol form which pairs with guanine. A mistake in base pairing which allows uracil in its enol form to enter the DNA molecule and pair with guanine can result in a G = C --> A = T base transition in the DNA molecule. The molecular mechanism involved as well as the possible bearing on somatic mutation are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214838"} {"pmid": "4214839", "title": "Comparative activity of ampicillin and seven cephalosporins against group D streptococci.", "content": "Comparative activity of ampicillin and seven cephalosporins against group D streptococci. Minimum inhibitory concentrations have been determined for ampicillin and seven cephalosporins against 93 strains of group D streptococci isolated recently from clinical material. Ampicillin was much the most active compound (modal MIC = 1.6 mug/ml); cephaloridine, cephacetrile, and cefazolin had a modal MIC of 25 mug/ml, while corresponding figures for cephalothin, cephradine, cephalexin, and cefoxitin were 50, 100, 200, and 800 mug/ml, respectively. Thus, none of the newer cephalosporins is an improvement in respect to activity against enterococci over existing compounds, and ampicillin remains overwhelmingly the beta-lactam antibiotic of choice for the treatment of infections by such organisms. Pharmacokinetic considerations, however, indicate that certain cephalosporins, for instance, cephaloridine, cefazolin, and cephanone, may be worthy of further study in view of possible synergy with aminoglycoside antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214839"} {"pmid": "4214840", "title": "Antibodies to Candida albicans in hospital patients with and without spinal injury and in normal men and women.", "content": "Antibodies to Candida albicans in hospital patients with and without spinal injury and in normal men and women. The presence of serum agglutinins and precipitins to Candida albicans in men and women who had impaired bladder function following spinal injury is compared with that in other patients in hospital and in apparently fit men and women. Antibody levels which have commonly been regarded as significant were found in 35 of 76 patients who had urinary candidiasis; in 10 of 52 patients who had spinal injury without urinary candidiasis; in eight of 57 patients who had neither of these conditions, and in nine of 191 normal men and women. Observations are made on the antigens involved in these reactions and on the need for standardization of both reagents and techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214840"} {"pmid": "4214841", "title": "Tests of disinfection by heat in a bedpan washing machine.", "content": "Tests of disinfection by heat in a bedpan washing machine. Tests of effectiveness of disinfection of metal and polypropylene bedpans were made in a washer fitted with a steam generator. Broth cultures of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, or Streptococcus faecalis (approximately 4 x 10(8) organisms) were sealed in lengths of capillary tubing and attached to the surface of the pans. In other tests, pans were contaminated with an artificial soil containing Str. faecalis (10(8) organisms/ml). In both series of tests, counts of surviving organisms were made at the end of the washing and disinfection cycle. The tests using capillary tubes showed that the Gram-negative bacilli were effectively killed, but not necessarily Gram-positive cocci. However, when incorporated in standard soil, Str. faecalis was killed or removed during the cycle. The results indicate that the disinfection process was effective for metal bedpans, but less so for polypropylene. Possible disadvantages and modification of the machine are suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214841"} {"pmid": "4214842", "title": "Alteration of classically conditioned heart rate by operant reinforcement in monkeys.", "content": "Alteration of classically conditioned heart rate by operant reinforcement in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214842"} {"pmid": "4214843", "title": "Effects of sequential preoptic and mammillary lesions on male rat sexual behavior.", "content": "Effects of sequential preoptic and mammillary lesions on male rat sexual behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214843"} {"pmid": "4214845", "title": "Acid etching: questions and answers.", "content": "Acid etching: questions and answers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214845"} {"pmid": "4214844", "title": "Behavioral diversity in ten species of nonhuman primates.", "content": "Behavioral diversity in ten species of nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214844"} {"pmid": "4214846", "title": "The health care revolution (or dental practice will never be the same).", "content": "The health care revolution (or dental practice will never be the same).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214846"} {"pmid": "4214847", "title": "Mouth guards in contact sports.", "content": "Mouth guards in contact sports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214847"} {"pmid": "4214848", "title": "(Need) divided by x minus (Demand) divided by xR equals orthodontist glut.", "content": "(Need) divided by x minus (Demand) divided by xR equals orthodontist glut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214848"} {"pmid": "4214850", "title": "\"Sorry doctor, but I disagree\".", "content": "\"Sorry doctor, but I disagree\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214850"} {"pmid": "4214849", "title": "Correction of trauma from occlusion in treatment of periodontal disease.", "content": "Correction of trauma from occlusion in treatment of periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214849"} {"pmid": "4214851", "title": "Ability to function with full dentures, natural dentition, and no dentition.", "content": "Ability to function with full dentures, natural dentition, and no dentition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214851"} {"pmid": "4214852", "title": "Factors affecting L-alanine induced germination of Bacillus spores.", "content": "Factors affecting L-alanine induced germination of Bacillus spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214852"} {"pmid": "4214855", "title": "[A comparison of the pathogenicity of two strains of Schistosoma mansoni in Cercopithecus aethiops monkeys in the Sudan].", "content": "[A comparison of the pathogenicity of two strains of Schistosoma mansoni in Cercopithecus aethiops monkeys in the Sudan].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214855"} {"pmid": "4214856", "title": "A cytochemical approach to the lipid composition of mitochondrial matrix granules in brown adipose tissue and liver.", "content": "A cytochemical approach to the lipid composition of mitochondrial matrix granules in brown adipose tissue and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214856"} {"pmid": "4214857", "title": "First cases of diphtheria in Aruba (Dutch West Indies).", "content": "First cases of diphtheria in Aruba (Dutch West Indies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214857"} {"pmid": "4214858", "title": "Contribution to knowledge of factors participating in virulence of Listeria monocytogenes. II. Study of the chemical nature of complex Ei.", "content": "Contribution to knowledge of factors participating in virulence of Listeria monocytogenes. II. Study of the chemical nature of complex Ei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214858"} {"pmid": "4214859", "title": "Isolation of type - specific substances from Corynebacterium diphthermiae cells.", "content": "Isolation of type - specific substances from Corynebacterium diphthermiae cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214859"} {"pmid": "4214860", "title": "Shigella surveillance in Czechoslovakia.", "content": "Shigella surveillance in Czechoslovakia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214860"} {"pmid": "4214861", "title": "The phases of Coxiella burneti and its immunosorbents.", "content": "The phases of Coxiella burneti and its immunosorbents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214861"} {"pmid": "4214853", "title": "Total viable count of microorganisms in the infected dental pulp.", "content": "Total viable count of microorganisms in the infected dental pulp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214853"} {"pmid": "4214862", "title": "Allergens of mammalian origin. III. Properties of a major feline allergen.", "content": "Allergens of mammalian origin. III. Properties of a major feline allergen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214862"} {"pmid": "4214863", "title": "Antibodies to proteins dissolved in sodium dodecyl sulfate.", "content": "Antibodies to proteins dissolved in sodium dodecyl sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214863"} {"pmid": "4214864", "title": "Cross-idiotypic specificity of rat antibodies to group A streptococcal carbohydrate.", "content": "Cross-idiotypic specificity of rat antibodies to group A streptococcal carbohydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214864"} {"pmid": "4214865", "title": "Anti-idiotypic antibody in rat transplantation immunity. I. Production of anti-idiotypic antibody in animals repeatedly immunized with alloantigens.", "content": "Anti-idiotypic antibody in rat transplantation immunity. I. Production of anti-idiotypic antibody in animals repeatedly immunized with alloantigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214865"} {"pmid": "4214866", "title": "Mononuclear cell chemotactic activity of kallikrein and plasminogen activator and its inhibition by C1 inhibitor and alpha 2-macroglobulin.", "content": "Mononuclear cell chemotactic activity of kallikrein and plasminogen activator and its inhibition by C1 inhibitor and alpha 2-macroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214866"} {"pmid": "4214868", "title": "Molecular analysis of the reaction of C9 with EAC1-8: reaction of C9 with EAC1-8.", "content": "Molecular analysis of the reaction of C9 with EAC1-8: reaction of C9 with EAC1-8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214868"} {"pmid": "4214867", "title": "Expression of IgG allotypes in human lymphoid tumor lines serially transplantable in the neonatal Syrian hamster.", "content": "Expression of IgG allotypes in human lymphoid tumor lines serially transplantable in the neonatal Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214867"} {"pmid": "4214854", "title": "Fate of polychlorinated biphenyls, metals, and other elements in papers fed to lactating cows.", "content": "Fate of polychlorinated biphenyls, metals, and other elements in papers fed to lactating cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214854"} {"pmid": "4214869", "title": "Cellular immunity to Leishmania donovani. I. The effect of T cell depletion on resistance to L. donovani in mice.", "content": "Cellular immunity to Leishmania donovani. I. The effect of T cell depletion on resistance to L. donovani in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214869"} {"pmid": "4214871", "title": "Photography of faint immunodiffusion zones.", "content": "Photography of faint immunodiffusion zones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214871"} {"pmid": "4214870", "title": "A pathologic IgM occurring in serum as pentamer, dimer, and monomer.", "content": "A pathologic IgM occurring in serum as pentamer, dimer, and monomer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214870"} {"pmid": "4214872", "title": "A controlled quantitative study of parotid salivary secretory IgA-globulin in normal adults.", "content": "A controlled quantitative study of parotid salivary secretory IgA-globulin in normal adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214872"} {"pmid": "4214873", "title": "Study of adenovirus hexon antigen--antibody reactions by single radial diffusion techniques.", "content": "Study of adenovirus hexon antigen--antibody reactions by single radial diffusion techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214873"} {"pmid": "4214874", "title": "The use of peroxidase-labelled antiglobulin for ultrastructural localization of tissue antigens reacting with serum antibodies.", "content": "The use of peroxidase-labelled antiglobulin for ultrastructural localization of tissue antigens reacting with serum antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214874"} {"pmid": "4214875", "title": "Radioimmunoassay techniques for detecting naturally occurring viral antibody in human sera.", "content": "Radioimmunoassay techniques for detecting naturally occurring viral antibody in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214875"} {"pmid": "4214876", "title": "Staphylococcal toxic epidermal necrolysis (TEN): the expanded mouse model.", "content": "Staphylococcal toxic epidermal necrolysis (TEN): the expanded mouse model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214876"} {"pmid": "4214878", "title": "Histidase activity in rat liver and epidermis.", "content": "Histidase activity in rat liver and epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214878"} {"pmid": "4214877", "title": "Chromatographic fractionation and partial characterization of acid phosphatase in guinea-pig epidermis.", "content": "Chromatographic fractionation and partial characterization of acid phosphatase in guinea-pig epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214877"} {"pmid": "4214879", "title": "Serum immunoglobulin in scabies.", "content": "Serum immunoglobulin in scabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214879"} {"pmid": "4214880", "title": "In vitro studies of the action of antibiotics on Rickettsia prowazeki by two basic methods of cell culture.", "content": "In vitro studies of the action of antibiotics on Rickettsia prowazeki by two basic methods of cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214880"} {"pmid": "4214881", "title": "Chute-hydropulping waste disposal system: a reservoir of enteric bacilli and pseudomonas in a modern hospital.", "content": "Chute-hydropulping waste disposal system: a reservoir of enteric bacilli and pseudomonas in a modern hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214881"} {"pmid": "4214882", "title": "The case for gonococcal serology.", "content": "The case for gonococcal serology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214882"} {"pmid": "4214887", "title": "Pharyngo-cutaneous fistulae in totally laryngectomized patients.", "content": "Pharyngo-cutaneous fistulae in totally laryngectomized patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214887"} {"pmid": "4214888", "title": "Why accelerators in radiation therapy?", "content": "Why accelerators in radiation therapy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214888"} {"pmid": "4214889", "title": "Breast cancer management.", "content": "Breast cancer management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214889"} {"pmid": "4214890", "title": "The involvement of lactoferrin in the hyposideremia of acute inflammation.", "content": "The involvement of lactoferrin in the hyposideremia of acute inflammation. The hyposideremia of inflammation was found to be based on a three-step mechanism involving lactoferrin, the iron-binding protein from the specific granules of neutrophilic leukocytes. (a) Lactoferrin is Released from Neutrophils in an Iron-Free Form. When phagocytosis was induced in neutrophils by zymosan or bacteria, lactoferrin was recovered in the incubation medium together with other constituents of the specific granules, such as alkaline phosphatase and lysozyme. Lactoferrin extracted from leukocytes was able to bind the amount of iron corresponding to its theoretical iron-binding capacity. After injection of endotoxin into rats, lactoferrin was detected in various tissues where it was normally absent, or in the plasma when the reticuloendothelial system (RES) had previously been blocked by injections of India ink or aggregated albumin. (b) Lactoferrin is Able to Remove the Iron from Transferrin. Significant exchange of iron from transferrin to lactoferrin was observed in vitro only at a pH below 7.0 or in the presence of a high concentration of citrate. However, the fast elimination of lactoferrin in vivo, when saturated with iron, might account for the observed transfer of iron to endogenous or administered apolactoferrin. Intravenous injection of human apolactoferrin into rats caused a marked decrease of the plasma iron level. The kinetics of this process, as well as controls with other proteins, ruled out the possibility of a secondary inflammatory effect due to phlogogenic contaminants. (c) Fe-Lactoferrin is Taken-up by the RES. By immunofluorescence, lactoferrin was shown to be bound and ingested by monocytes. The rate of elimination of human Fe-lactoferrin injected into rats was particularly fast when compared to that of human apolactoferrin, succinylated Fe-lactoferrin, or other human proteins. Blockade of the RES slowed down the rate of clearance of Fe-lactoferrin and was also found to retard the elimination of endogenous rat lactoferrin released by endotoxin. These experiments suggest the existence of specific receptors for Fe-lactoferrin on the membrane of macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214890"} {"pmid": "4214892", "title": "Further observations on genetic transformation in pseudomonas.", "content": "Further observations on genetic transformation in pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214892"} {"pmid": "4214891", "title": "The interaction of IgE with rat basophilic leukemia cells. II. Quantitative aspects of the binding reaction.", "content": "The interaction of IgE with rat basophilic leukemia cells. II. Quantitative aspects of the binding reaction. Previous studies indicated that cultured rat basophilic leukemia cells have surface receptors which bind IgE with high specificity. In this paper we describe some quantitative aspects of the phenomenon. The reaction mechanism appears to consist of a simple reversible binding reaction with k(1) = 9.6 x 10(4) M(-1) sec(-1) and k(-1) 1.6 x 10(-5) sec(-1) at 37 degrees C. The calculated K(A) is therefore 6 x 10(9) M(-1). The activation energy of binding was found to be 7.8 kcal/mol. The number of binding sites/cell varied between 3 x 10(5) to over 1 x 10(6). The binding was insensitive to pH's between 6-8 but at pH 3.0 complete dissociation of bound IgE occurred in approximately 1 min at 0 degrees C leaving the receptors for IgE intact. Ca(++) plus EDTA and Mg(++) plus EDTA produce a fairly marked reduction in binding capacity though these reagents alone produce much smaller effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214891"} {"pmid": "4214893", "title": "The effect of proflavin, ethidium bromide and an elevated temperature on the appearance of nisin-negative clones in nisin-producing strains of Streptococcus lactis.", "content": "The effect of proflavin, ethidium bromide and an elevated temperature on the appearance of nisin-negative clones in nisin-producing strains of Streptococcus lactis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214893"} {"pmid": "4214894", "title": "Properties of a mutant of Pseudomonas aeruginosa affected in aerobic growth.", "content": "Properties of a mutant of Pseudomonas aeruginosa affected in aerobic growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214894"} {"pmid": "4214895", "title": "Control of macromolecular composition and cell division in the blue-green algae Anacystis nidulans.", "content": "Control of macromolecular composition and cell division in the blue-green algae Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214895"} {"pmid": "4214896", "title": "Selection of a mutant of Bacillus subtilis deficient in glucose-6-phosphate dehydrogenase and phosphoglucoisomerase.", "content": "Selection of a mutant of Bacillus subtilis deficient in glucose-6-phosphate dehydrogenase and phosphoglucoisomerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214896"} {"pmid": "4214897", "title": "Comparison of antigenic glycoproteins and glycoprotein receptors of concanavalin A isolated from duck embryo cells infected with Marek's disease virus and a herpes virus of turkeys (strain FC126).", "content": "Comparison of antigenic glycoproteins and glycoprotein receptors of concanavalin A isolated from duck embryo cells infected with Marek's disease virus and a herpes virus of turkeys (strain FC126).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214897"} {"pmid": "4214898", "title": "Alterations of the immunological specificity of plasma membranes from cells infected with Marek's disease and turkey herpes viruses.", "content": "Alterations of the immunological specificity of plasma membranes from cells infected with Marek's disease and turkey herpes viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214898"} {"pmid": "4214899", "title": "Photosensitization of cyanophage N-1.", "content": "Photosensitization of cyanophage N-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214899"} {"pmid": "4214900", "title": "Studies to improve fixation of human nerves. 1. Effect of duration of glutaraldehyde fixation on peripheral nerve morphometry.", "content": "Studies to improve fixation of human nerves. 1. Effect of duration of glutaraldehyde fixation on peripheral nerve morphometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214900"} {"pmid": "4214901", "title": "Studies to improve fixation of human nerves. 2. Effect of time elapsed between death and glutaraldehyde fixation on relationship of axonal area to number of myelin lamellae.", "content": "Studies to improve fixation of human nerves. 2. Effect of time elapsed between death and glutaraldehyde fixation on relationship of axonal area to number of myelin lamellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214901"} {"pmid": "4214902", "title": "An economic, semiautomatic method for in vitro thyroid function tests.", "content": "An economic, semiautomatic method for in vitro thyroid function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214902"} {"pmid": "4214904", "title": "Response of nitrogen metabolism, plasma amino acids and insulin levels to various levels of methionine infusion in sheep.", "content": "Response of nitrogen metabolism, plasma amino acids and insulin levels to various levels of methionine infusion in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214904"} {"pmid": "4214903", "title": "Responses of growing lambs to abomasal infusion of corn oil, starch, casein, and amino acid mixtures.", "content": "Responses of growing lambs to abomasal infusion of corn oil, starch, casein, and amino acid mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214903"} {"pmid": "4214905", "title": "Biological tests of a temporary crown and bridge material.", "content": "Biological tests of a temporary crown and bridge material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214905"} {"pmid": "4214907", "title": "Studies on host-parasite relationships of Simuliidae with mermithids and microsporidans.", "content": "Studies on host-parasite relationships of Simuliidae with mermithids and microsporidans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214907"} {"pmid": "4214906", "title": "Isolation and partial characterization of exo- and endoantigens of Cooperia punctata cultured in vitro.", "content": "Isolation and partial characterization of exo- and endoantigens of Cooperia punctata cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214906"} {"pmid": "4214908", "title": "Entopolypoides macaci (Babesiidae) in Macaca mulatta.", "content": "Entopolypoides macaci (Babesiidae) in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214908"} {"pmid": "4214909", "title": "Immunochemical studies on East Coast fever. I. Partial segregation and characterization of the Theileria parva schizont antigen.", "content": "Immunochemical studies on East Coast fever. I. Partial segregation and characterization of the Theileria parva schizont antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214909"} {"pmid": "4214910", "title": "Immunochemical studies on East Coast fever. II. Partial segregation and characterization of the Theileria parva piroplasm antigen.", "content": "Immunochemical studies on East Coast fever. II. Partial segregation and characterization of the Theileria parva piroplasm antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214910"} {"pmid": "4214912", "title": "Pulmonary parenchymal damage complicating intravenous alimentation.", "content": "Pulmonary parenchymal damage complicating intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214912"} {"pmid": "4214911", "title": "Immunochemical studies on East Coast fever. III. Development of an indirect hemagglutination assay using Theileria parva piroplasm antigen.", "content": "Immunochemical studies on East Coast fever. III. Development of an indirect hemagglutination assay using Theileria parva piroplasm antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214911"} {"pmid": "4214913", "title": "Variations in intravenous nutrition in the management of catabolic states in infants and children.", "content": "Variations in intravenous nutrition in the management of catabolic states in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214913"} {"pmid": "4214914", "title": "Syntheses and antimicrobial properties of isothiocyanate derivatives.", "content": "Syntheses and antimicrobial properties of isothiocyanate derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214914"} {"pmid": "4214916", "title": "Letter: Development of a stable sublingual nitroglycerin tablet I: interaction of nitroglycerin with selected macromolecules.", "content": "Letter: Development of a stable sublingual nitroglycerin tablet I: interaction of nitroglycerin with selected macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214916"} {"pmid": "4214915", "title": "Transport mechanisms of beta-lactam antibiotics across everted rat gut.", "content": "Transport mechanisms of beta-lactam antibiotics across everted rat gut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214915"} {"pmid": "4214917", "title": "Photoelectron spectra, hydrolytic stability, and antimicrobial activity of N-chlorinated piperidines.", "content": "Photoelectron spectra, hydrolytic stability, and antimicrobial activity of N-chlorinated piperidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214917"} {"pmid": "4214918", "title": "Formulation and in vitro evaluation of anti-infective dry foams.", "content": "Formulation and in vitro evaluation of anti-infective dry foams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214918"} {"pmid": "4214919", "title": "Synthesis and antibacterial activity of 5-nitro-2-furfurylidene p-sulfonyl- and p-sulfamoylbenzoylhydrazides. VII.", "content": "Synthesis and antibacterial activity of 5-nitro-2-furfurylidene p-sulfonyl- and p-sulfamoylbenzoylhydrazides. VII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214919"} {"pmid": "4214920", "title": "Isolation of an acidic glycoprotein from rabbit oviducal fluid and its association with the egg coating.", "content": "Isolation of an acidic glycoprotein from rabbit oviducal fluid and its association with the egg coating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214920"} {"pmid": "4214921", "title": "Calcium and zinc in the endometrium and uterine flushings of the roe deer (Capreolus capreolus) during delayed implantation.", "content": "Calcium and zinc in the endometrium and uterine flushings of the roe deer (Capreolus capreolus) during delayed implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214921"} {"pmid": "4214922", "title": "Failure to demonstrate a rôle for the acute release of prolactin at oestrus in the ewe.", "content": "Failure to demonstrate a rôle for the acute release of prolactin at oestrus in the ewe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214922"} {"pmid": "4214923", "title": "A technique for obtaining precise chromosome and bilirubin studies on amniotic fluid in twin pregnancy.", "content": "A technique for obtaining precise chromosome and bilirubin studies on amniotic fluid in twin pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214923"} {"pmid": "4214924", "title": "Synthesis and antifolate activity of isoaminopterin.", "content": "Synthesis and antifolate activity of isoaminopterin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214924"} {"pmid": "4214925", "title": "Pyrimido(4,5-c)isoquinolines. 2. Synthesis and biological evaluation of some 6-alkyl-,6-aralkyl-, and 6-aryl-1,3-diamino-7,8,9,10-tetrahydropyrimido(4,5-c)isoquinolines as potential folate antagnoists 1.", "content": "Pyrimido(4,5-c)isoquinolines. 2. Synthesis and biological evaluation of some 6-alkyl-,6-aralkyl-, and 6-aryl-1,3-diamino-7,8,9,10-tetrahydropyrimido(4,5-c)isoquinolines as potential folate antagnoists 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214925"} {"pmid": "4214926", "title": "Effect of lipophilic substituents on some biological properties of indoles.", "content": "Effect of lipophilic substituents on some biological properties of indoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214926"} {"pmid": "4214927", "title": "Selective binding of metal ions to macromolecules using bifunctional analogs of EDTA.", "content": "Selective binding of metal ions to macromolecules using bifunctional analogs of EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214927"} {"pmid": "4214928", "title": "Methotrexate analogs. 4.7-Methyl derivatives of methotrexate and dichloromethotrexate. A new synthesis and some biological studies.", "content": "Methotrexate analogs. 4.7-Methyl derivatives of methotrexate and dichloromethotrexate. A new synthesis and some biological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214928"} {"pmid": "4214929", "title": "Semisynthetic beta-lactam antibiotics. 6. 1 Sulfocephalosporins and their antipseudomonal activities.", "content": "Semisynthetic beta-lactam antibiotics. 6. 1 Sulfocephalosporins and their antipseudomonal activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214929"} {"pmid": "4214930", "title": "Familial thyroxine-binding globulin deficiency: search for linkage with Xg blood groups.", "content": "Familial thyroxine-binding globulin deficiency: search for linkage with Xg blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214930"} {"pmid": "4214932", "title": "A comparison of three different electron microscopical grade glutaraldehydes used to fix ovarian tissue.", "content": "A comparison of three different electron microscopical grade glutaraldehydes used to fix ovarian tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214932"} {"pmid": "4214933", "title": "Sporulation-specific translational discrimination in Bacillus subtilis.", "content": "Sporulation-specific translational discrimination in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214933"} {"pmid": "4214934", "title": "Isolation by affinity chromatography of a precursor head protein (P23) of bacteriophage T4.", "content": "Isolation by affinity chromatography of a precursor head protein (P23) of bacteriophage T4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214934"} {"pmid": "4214931", "title": "Electrical properties and diffusion potentials in the gallbladder of man, monkey, dog, goose and rabbit.", "content": "Electrical properties and diffusion potentials in the gallbladder of man, monkey, dog, goose and rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214931"} {"pmid": "4214935", "title": "Purification and properties of the isolated honeybee Z-disc.", "content": "Purification and properties of the isolated honeybee Z-disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214935"} {"pmid": "4214936", "title": "Effects of aminoethylation of cysteine residues on the structural and functional activities of the Escherichia coli 30 S ribosomal proteins.", "content": "Effects of aminoethylation of cysteine residues on the structural and functional activities of the Escherichia coli 30 S ribosomal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214936"} {"pmid": "4214937", "title": "Characterization of an antiserum against human myeloma cells.", "content": "Characterization of an antiserum against human myeloma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214937"} {"pmid": "4214938", "title": "Isolation of papovavirus from brain tumor and urine of a patient with Wiskott-Aldrich syndrome.", "content": "Isolation of papovavirus from brain tumor and urine of a patient with Wiskott-Aldrich syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214938"} {"pmid": "4214940", "title": "On diploid cell lines.", "content": "On diploid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214940"} {"pmid": "4214939", "title": "An in vitro micromethod for testing cytotoxic compounds.", "content": "An in vitro micromethod for testing cytotoxic compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214939"} {"pmid": "4214942", "title": "Alveolar macrophage in the burned rat.", "content": "Alveolar macrophage in the burned rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214942"} {"pmid": "4214943", "title": "Treatment of open crushing type of industrial injuries of the hand and forearm: degloving, open circumferential, heat-press, and nail-bed injuries.", "content": "Treatment of open crushing type of industrial injuries of the hand and forearm: degloving, open circumferential, heat-press, and nail-bed injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214943"} {"pmid": "4214941", "title": "Research on tissue culture at the National Cancer Institute, with special reference to the contributions of Dr. Virginia J. Evans.", "content": "Research on tissue culture at the National Cancer Institute, with special reference to the contributions of Dr. Virginia J. Evans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214941"} {"pmid": "4214944", "title": "Bacteriophage PBS2-induced deoxycytidine triphosphate deaminase in Bacillus subtilis.", "content": "Bacteriophage PBS2-induced deoxycytidine triphosphate deaminase in Bacillus subtilis. The dCTP deaminase induced by Bacillus subtilis bacteriophage PBS2, whose DNA contains uracil instead of thymine, requires metal ion and thiol activators and has a molecular weight of 125,000. The enzyme displays sigmoidal substrate saturation kinetics and inhibition by dUTP, consistent with the deaminase's proposed role of providing balanced levels of dUTP and dCTP for PBS2 uracil-DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214944"} {"pmid": "4214945", "title": "Bacillus subtilis DNA polymerase III is required for the replication of the virulent bacteriophage phi e.", "content": "Bacillus subtilis DNA polymerase III is required for the replication of the virulent bacteriophage phi e. The virulent phage phie of Bacillus subtilis which contains hydroxymethyluracil in its DNA requires host DNA polymerase III for its DNA replication. DNA polymerase III(ts) mutant cells infected with phie at restrictive temperatures do not support phage DNA synthesis. However, phie grows normally both at low and high temperatures in the mutant's parent strain and in spontaneous DNA polymerase III(+) revertants isolated from the mutant strain. Temperature-shift-down experiments with phie-infected cells having thermosensitive DNA polymerase III (pol III(ts)) indicate that at 48 C the thermolabile DNA polymerase III is irreversibly inactivated and has to be synthesized de novo after the shift to 37 C, before phage DNA synthesis can begin. Temperature-shift-up experiments with phie-infected mutant cells show that phage replication is arrested immediately after the temperature shift and indicate that phie requires DNA polymerase III throughout its replication stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214945"} {"pmid": "4214946", "title": "Transduction in Bacillus subtilis by bacteriophage SPP1.", "content": "Transduction in Bacillus subtilis by bacteriophage SPP1. Lysates of the virulent bacteriophage SPP1 were shown to be capable of mediating generalized transduction. Suppressible mutants of this bacteriophage (sus) were capable of transduction at a lower multiplicity of infection than virulent SPP1. Linkage analysis demonstrated that bacteriophage SPP1 transduced segments of the genome equal in size to that transferred by SP10. This bacteriophage should be useful in analyzing the regions of the genome where PBS1 appears to give anomalous results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214946"} {"pmid": "4214947", "title": "Mixed infections of Bacillus subtilis involving bacteriophages SP82 and beta 22.", "content": "Mixed infections of Bacillus subtilis involving bacteriophages SP82 and beta 22. Progeny yields and the synthesis of nucleic acids have been investigated in two strains of Bacillus subtilis mixedly infected with two unrelated phages, SP82 and beta22. When B. subtilis strain 168 was the host, the first phage added dominated the infection; when B. subtilis strain SB11 was the host, beta22 produced progeny even when added to cells 5 min after infection with SP82. Dominance in these mixed infections could be correlated with qualitative and quantitative differences in the synthesis of phage-specific RNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214947"} {"pmid": "4214948", "title": "Induction of prophage SPO2 in Bacillus subtilis by 6-(para)-hydroxyphenylazouracil.", "content": "Induction of prophage SPO2 in Bacillus subtilis by 6-(para)-hydroxyphenylazouracil. DNA replication in Bacillus subtilis is reversibly inhibited by 6-(para)-hydroxyphenylazouracil (HpUra) (1971), whereas replication of temperature phage SPO2 is not affected by the drug. Experiments are presented which show that HpUra will induce bacteria lysogenic for SPO2. Also, prophage phi105, which is sensitive to the drug, is induced by HpUra. Induction of SPO2 lysogenics in the presence of HpUra gives selective synthesis of SPO2 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214948"} {"pmid": "4214950", "title": "Origin and metabolic properties of the RNA species formed during the replication cycle of virus 2C.", "content": "Origin and metabolic properties of the RNA species formed during the replication cycle of virus 2C. When short pulses of [(3)H]uracil were administered to Bacillus subtilis infected with phage 2C, the main species of labeled RNA was a 10S component that hybridized chiefly, but not exclusively, with the heavy strand of 2C DNA. After long pulses, most of the radioactivity was found in the 23S, 16S, and 5S rRNA's, which are coded for by the cell genome. Formation of such RNA species was reduced but not suppressed upon infection, the extent of inhibition being proportional to the virus-to-cell ratio. When bacteria were incubated with virginiamycin, an inhibitor of protein synthesis, and then infected with phage 2C, formation of virus-specific RNA decreased. This antibiotic also reduced the preferential transcription of the heavy strand of 2C DNA. The methylation pattern of rRNA remained unchanged upon infection with phage 2C. Virginiamycin reduced both the methylation and stability of rRNA in uninfected cells; this effect, however, was clearly reduced during the viral cycle. It can be concluded that in 2C-infected B. subtilis, cellular and viral RNA species are simultaneously synthesized and a preferential transcription of viral message depends not only on the number of available copies of viral template, but also on their translation. Moreover, virus-dictated proteins are responsible for the inhibition of cellular RNA formation as well as for the asymmetrical transcription of phage genome. Finally, virginiamycin and phage 2C have antagonistic, nonoverlapping effects on the metabolism and function of the RNA of the host cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214950"} {"pmid": "4214949", "title": "Induction of prophage SPO2 in Bacillus subtilis: prophage excision in the absence of bacterial or bacteriophage DNA synthesis.", "content": "Induction of prophage SPO2 in Bacillus subtilis: prophage excision in the absence of bacterial or bacteriophage DNA synthesis. Bacillus subtilis lysogenic for SPO2 wild type was induced under conditions preventing synthesis of both bacterial and phage DNA. The infectivity of phage DNA in transfection is strongly decreased under these conditions, whereas the activity of single phage genes as measured by marker rescue with superinfecting phage is unaffected. DNA from induced cells was sedimented in neutral sucrose gradients. After induction, phage DNA was detected at a position in the gradients, which was different from the bulk of the bacterial DNA, corresponding to linear double-stranded DNA of about 25 x 10(6) daltons. Similar results were obtained with bacteria lysogenic for a SPO2 prophage carrying a DNA-negative mutation. No separation of phage and bacterial DNA activity was detected when chloramphenicol was present during the induction period. These experiments show that prophage SPO2 can excise from the bacterial chromosome without previous replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214949"} {"pmid": "4214951", "title": "In vivo and in vitro transcription of SPP1 DNA by host RNA polymerase.", "content": "In vivo and in vitro transcription of SPP1 DNA by host RNA polymerase. Most (if not all) SPP1 RNA can be synthesized in infected cells in the presence of chloramphenicol, or in vitro by Bacillus subtilis RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214951"} {"pmid": "4214954", "title": "A statistical method for comparison and classification of the microfilarial periodicity.", "content": "A statistical method for comparison and classification of the microfilarial periodicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214954"} {"pmid": "4214955", "title": "Pathogenic and antigenic properties of the Tyzzer's organisms from feline and hamster cases.", "content": "Pathogenic and antigenic properties of the Tyzzer's organisms from feline and hamster cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214955"} {"pmid": "4214956", "title": "A comparative study of mycobacteria from patients' room dusts and from sputa of tuberculous patients. Source of pathogenic mycobacteria occurring in the sputa of tuberculous patients as casual isolates.", "content": "A comparative study of mycobacteria from patients' room dusts and from sputa of tuberculous patients. Source of pathogenic mycobacteria occurring in the sputa of tuberculous patients as casual isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214956"} {"pmid": "4214957", "title": "Preparation of an adjuvant-active, tuberculin-free peptidoglycolipid from human tubercle bacilli.", "content": "Preparation of an adjuvant-active, tuberculin-free peptidoglycolipid from human tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214957"} {"pmid": "4214958", "title": "Further confirmation of the avirulence of Streptococcus faecalis strain BIO-4R.", "content": "Further confirmation of the avirulence of Streptococcus faecalis strain BIO-4R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214958"} {"pmid": "4214959", "title": "Littré's femoral hernia causing intestinal fistula.", "content": "Littré's femoral hernia causing intestinal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214959"} {"pmid": "4214965", "title": "Further scanning electron microscope studies of the human glomerulus.", "content": "Further scanning electron microscope studies of the human glomerulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214965"} {"pmid": "4214966", "title": "The ultrastructure of the skin in patients with mucopolysaccharidoses.", "content": "The ultrastructure of the skin in patients with mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214966"} {"pmid": "4214967", "title": "The content of some B-group vitamins in single-variety apple juices and commercial ciders.", "content": "The content of some B-group vitamins in single-variety apple juices and commercial ciders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214967"} {"pmid": "4214968", "title": "Progesterone and oestrogen metabolism in the pregnant marmoset (Callithrix jacchus).", "content": "Progesterone and oestrogen metabolism in the pregnant marmoset (Callithrix jacchus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214968"} {"pmid": "4214969", "title": "Detection of hepatitis-associated antigen. The latex agglutination test.", "content": "Detection of hepatitis-associated antigen. The latex agglutination test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214969"} {"pmid": "4214971", "title": "Gastrointestinal alterations in protein-calorie malnutrition.", "content": "Gastrointestinal alterations in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214971"} {"pmid": "4214970", "title": "Esophageal physiology.", "content": "Esophageal physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214970"} {"pmid": "4214977", "title": "Amino acid metabolism in parenteral nutrition: with special reference to the calorie: nitrogen ratio and the blood urea nitrogen level.", "content": "Amino acid metabolism in parenteral nutrition: with special reference to the calorie: nitrogen ratio and the blood urea nitrogen level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214977"} {"pmid": "4214978", "title": "Medicine and millions.", "content": "Medicine and millions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214978"} {"pmid": "4214979", "title": "Letter: Psychosis associated with sympathomimetic and cromoglycate therapy.", "content": "Letter: Psychosis associated with sympathomimetic and cromoglycate therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214979"} {"pmid": "4214980", "title": "Editorial: Famine in Ethiopia.", "content": "Editorial: Famine in Ethiopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214980"} {"pmid": "4214982", "title": "Editorial: Management of maternal isoimmunization.", "content": "Editorial: Management of maternal isoimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214982"} {"pmid": "4214981", "title": "Total parenteral nutrition in paediatric patients.", "content": "Total parenteral nutrition in paediatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214981"} {"pmid": "4214983", "title": "The liquor amnii bilirubin-protein ratio in the management of Rhesus isoimmunization.", "content": "The liquor amnii bilirubin-protein ratio in the management of Rhesus isoimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214983"} {"pmid": "4214984", "title": "Tobramycin therapy in renal failure.", "content": "Tobramycin therapy in renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214984"} {"pmid": "4214990", "title": "The specificity of transcription in vitro of the tryptophan operon of Escherichia coli. II. The effect of Rho factor.", "content": "The specificity of transcription in vitro of the tryptophan operon of Escherichia coli. II. The effect of Rho factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214990"} {"pmid": "4214991", "title": "Biosynthesis of RNA polymerase in Escherichia coli. I. Control of RNA polymerase content at various growth rates.", "content": "Biosynthesis of RNA polymerase in Escherichia coli. I. Control of RNA polymerase content at various growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214991"} {"pmid": "4214992", "title": "The analog inhibitor, alpha-methyl dopa, as a screening agent for mutants elevating levels of dopa decarboxylase activity in Drosophila melanogaster.", "content": "The analog inhibitor, alpha-methyl dopa, as a screening agent for mutants elevating levels of dopa decarboxylase activity in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214992"} {"pmid": "4214987", "title": "Bremsstrahlung radiators and beam filters for 25-MeV cancer therapy.", "content": "Bremsstrahlung radiators and beam filters for 25-MeV cancer therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214987"} {"pmid": "4214993", "title": "Transformation in Bacillus subtilis using excreted DNA.", "content": "Transformation in Bacillus subtilis using excreted DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214993"} {"pmid": "4214994", "title": "A spectrophotometric study of the interaction of deoxyribonucleoproteins with the acriflavine-phosphotungstic acid complex.", "content": "A spectrophotometric study of the interaction of deoxyribonucleoproteins with the acriflavine-phosphotungstic acid complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214994"} {"pmid": "4214988", "title": "Experimental determination of the need for multitaper collimators for neutron radiotherapy.", "content": "Experimental determination of the need for multitaper collimators for neutron radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214988"} {"pmid": "4214995", "title": "Macromolecular structure of the DNA of Bacillus bacteriophages.", "content": "Macromolecular structure of the DNA of Bacillus bacteriophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214995"} {"pmid": "4214996", "title": "Errors in DNA replication in bacteria in the presence of a thymidylic acid deficiency.", "content": "Errors in DNA replication in bacteria in the presence of a thymidylic acid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214996"} {"pmid": "4214997", "title": "The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement.", "content": "The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214997"} {"pmid": "4214999", "title": "Production of L-phenylalanine by DL-phenylalanine hydroxamate-resistant Tyr- mutants of Bacillus subtilis.", "content": "Production of L-phenylalanine by DL-phenylalanine hydroxamate-resistant Tyr- mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214999"} {"pmid": "4214998", "title": "Separation of two monoamine oxidases from bovine bran.", "content": "Separation of two monoamine oxidases from bovine bran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4214998"} {"pmid": "4215000", "title": "Isolation and characterization of a 5S RNA-protein complex from human placental ribosomes.", "content": "Isolation and characterization of a 5S RNA-protein complex from human placental ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215000"} {"pmid": "4215016", "title": "Investigation on radiosensitive and radioresistant populations of Drosophila melanogaster. VI. Selection for further increase in relative radioresistance of stage-7 oocytes of the irradiated population RO I.", "content": "Investigation on radiosensitive and radioresistant populations of Drosophila melanogaster. VI. Selection for further increase in relative radioresistance of stage-7 oocytes of the irradiated population RO I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215016"} {"pmid": "4215017", "title": "Dose protraction and induced compound autosome non-disjunction in immature oocytes of Drosophila melanogaster.", "content": "Dose protraction and induced compound autosome non-disjunction in immature oocytes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215017"} {"pmid": "4215018", "title": "The effects of radiation exposure-rate and exposure fractionation on the frequencies of recessive and dominant lethals in immature oocytes of Drosophila melanogaster.", "content": "The effects of radiation exposure-rate and exposure fractionation on the frequencies of recessive and dominant lethals in immature oocytes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215018"} {"pmid": "4215019", "title": "A model to explain the response of stage 7 oocytes of Drosophila to the induction of dominant lethals under conditions of exposure-protraction and fractionation.", "content": "A model to explain the response of stage 7 oocytes of Drosophila to the induction of dominant lethals under conditions of exposure-protraction and fractionation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215019"} {"pmid": "4215020", "title": "The development and evaluation of immunodiffusion, immunofluorescence and physiological tests for the differentiation of atypical Trichophyton rubrum and T. mentagrophytes isolates.", "content": "The development and evaluation of immunodiffusion, immunofluorescence and physiological tests for the differentiation of atypical Trichophyton rubrum and T. mentagrophytes isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215020"} {"pmid": "4215021", "title": "Failure of disodium etidronate in calcinosis due to dermatomyositis and scleroderma.", "content": "Failure of disodium etidronate in calcinosis due to dermatomyositis and scleroderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215021"} {"pmid": "4215022", "title": "Letter: TRH and urinary urgency.", "content": "Letter: TRH and urinary urgency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215022"} {"pmid": "4215023", "title": "Letter: Children, diabetic ketoacidosis, 2,3-DPG, and growth potential.", "content": "Letter: Children, diabetic ketoacidosis, 2,3-DPG, and growth potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215023"} {"pmid": "4215024", "title": "Medicine and Public Affairs. From the tapes: Mr. Nixon on cholesterol, insomnia, etc.", "content": "Medicine and Public Affairs. From the tapes: Mr. Nixon on cholesterol, insomnia, etc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215024"} {"pmid": "4215025", "title": "Release of enzymes from cell walls by an endopectate-trans-eliminase.", "content": "Release of enzymes from cell walls by an endopectate-trans-eliminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215025"} {"pmid": "4215026", "title": "New RNA polymerase from Bacillus subtilis infected with phage PBS2.", "content": "New RNA polymerase from Bacillus subtilis infected with phage PBS2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215026"} {"pmid": "4215028", "title": "Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity.", "content": "Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215028"} {"pmid": "4215027", "title": "In vitro activity of cells from genetically lethal embryos of Drosophila.", "content": "In vitro activity of cells from genetically lethal embryos of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215027"} {"pmid": "4215029", "title": "TRH: a possible mediator of thermoregulation.", "content": "TRH: a possible mediator of thermoregulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215029"} {"pmid": "4215030", "title": "Transfection of non-host bacterial spheroplasts with bacteriophage phi chi 174 DNA.", "content": "Transfection of non-host bacterial spheroplasts with bacteriophage phi chi 174 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215030"} {"pmid": "4215031", "title": "Decline of PCB concentrations in North Atlantic surface water.", "content": "Decline of PCB concentrations in North Atlantic surface water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215031"} {"pmid": "4215032", "title": "Precocious development of detoxicating enzymes following pituitary graft.", "content": "Precocious development of detoxicating enzymes following pituitary graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215032"} {"pmid": "4215033", "title": "Presence of J chain in human immunocytes containing various immunoglobulin classes.", "content": "Presence of J chain in human immunocytes containing various immunoglobulin classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215033"} {"pmid": "4215035", "title": "Evidence for a direct effect of LRF and TRF on single unit activity in the rostral hypothalamus.", "content": "Evidence for a direct effect of LRF and TRF on single unit activity in the rostral hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215035"} {"pmid": "4215034", "title": "Bacterial mutation affecting T4 phage DNA synthesis and tail production.", "content": "Bacterial mutation affecting T4 phage DNA synthesis and tail production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215034"} {"pmid": "4215036", "title": "Editorial: Intercellular junctions: sites of permeability barriers and cellular communication.", "content": "Editorial: Intercellular junctions: sites of permeability barriers and cellular communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215036"} {"pmid": "4215037", "title": "Neutrophil function in congenital phosphoglycerate kinase deficiency.", "content": "Neutrophil function in congenital phosphoglycerate kinase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215037"} {"pmid": "4215038", "title": "In vitro maturation of precursors of 5S ribosomal RNA from Bacillus subtilis.", "content": "In vitro maturation of precursors of 5S ribosomal RNA from Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215038"} {"pmid": "4215040", "title": "Immunoglobulin of T lymphoma cells is an integral membrane protein.", "content": "Immunoglobulin of T lymphoma cells is an integral membrane protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215040"} {"pmid": "4215039", "title": "Candidate for immunoglobulin D present on murine B lymphocytes.", "content": "Candidate for immunoglobulin D present on murine B lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215039"} {"pmid": "4215041", "title": "Immunochemical analysis of IgD-lambda paraprotein in myeloma.", "content": "Immunochemical analysis of IgD-lambda paraprotein in myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215041"} {"pmid": "4215044", "title": "Orosomucoid and haptoglobin excretion in rat glomerulonephritis and tubulonephritis.", "content": "Orosomucoid and haptoglobin excretion in rat glomerulonephritis and tubulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215044"} {"pmid": "4215062", "title": "Long-term management of heart defects.", "content": "Long-term management of heart defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215062"} {"pmid": "4215063", "title": "Diabetes mellitus in childhood.", "content": "Diabetes mellitus in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215063"} {"pmid": "4215064", "title": "Breast-feeding: second thoughts.", "content": "Breast-feeding: second thoughts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215064"} {"pmid": "4215067", "title": "Rehabilitation of the long-stay schizophrenic.", "content": "Rehabilitation of the long-stay schizophrenic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215067"} {"pmid": "4215066", "title": "Lupus nephritis: long-term follow-up.", "content": "Lupus nephritis: long-term follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215066"} {"pmid": "4215068", "title": "Nursing care study: a losing battle?", "content": "Nursing care study: a losing battle?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215068"} {"pmid": "4215069", "title": "Rheumatic diseases in the community.", "content": "Rheumatic diseases in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215069"} {"pmid": "4215070", "title": "Boredom in long-stay hospitals.", "content": "Boredom in long-stay hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215070"} {"pmid": "4215071", "title": "The SEN in the psychiatric hospital.", "content": "The SEN in the psychiatric hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215071"} {"pmid": "4215074", "title": "Evidence for somatic generation of antibody diversity.", "content": "Evidence for somatic generation of antibody diversity. RNA preparations containing 70-80% mouse kappa-chain mRNA have been prepared. The remainder consists of many RNA species, each of which represents a small fraction of the total RNA. The kappa-chain mRNA preparation hybridizes with mouse liver DNA with bi-phasic kinetics, indicating that it consists of two fractions -\"unique\" and \"reiterated.\" Competition hybridization experiments show that the homology among the unique fractions from different mRNAs is the same as the homology among the amino acid sequences of the corresponding kappa-chains. Hence, in addition to the C-region (constant-region) sequences, (most of) the V-region (variable-region) sequences are also derived from unique germ line genes. The reiterated fractions from different kappa-chain mRNAs show essentially complete homology with each other. This fraction seems to consist mostly of sequences which do not code for amino-acid sequences of the secreted polypeptide chain, i.e., the \"external\" section of the mRNA molecule. It is concluded that the number of germ line genes is too small to account for the observed diversity of antibody molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215074"} {"pmid": "4215075", "title": "Antiinflammatory effects of murine malignant cells.", "content": "Antiinflammatory effects of murine malignant cells. Development of teratocarcinoma does not impair immunization of mice against Listeria monocytogenes. Endotoxin injection a short time before tumor cell inoculation allows the growth of teratocarcinoma in non syngenic mice despite immune stimulation. In contrast with this absence of impaired systematic immunity, teratocarcinoma cells were found to repulse macrophages in vitro. This effect on macrophages was also found with three other malignant cells and with trophoblast cells. In vivo, teratocarcinoma cells were found to impair local inflammation. These cells and other malignant cells are able to produce a compound(s) of molecular weight between 10(3) and 10(4), which prevents inflammatory reaction. These results suggest that mouse teratocarcinomas and other tumors by-pass the host immunological system of surveillance by at least two mechanisms: a direct toxic effect on macrophages and the release of an inhibitor of inflammation. The possible relations between these properties of malignant cells and physiological functions of trophoblast are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215075"} {"pmid": "4215076", "title": "Mouse immunoglobulin heavy chains are coded by multiple germ line variable region genes.", "content": "Mouse immunoglobulin heavy chains are coded by multiple germ line variable region genes. The N-terminal 20 residues of 13 heavy immunoglobulin chains from myeloma protein of the BALB/c mouse are compared with the same residues of 15 other heavy chains described in the literature. Sixteen of 28 sequences are different from one another. These proteins fall into four major sets, with 18 of the proteins in the largest set being further divisible into at least five subsets. This pattern of diversity suggests there are at least eight germ line genes coding for the variable regions of mouse heavy chain. Many of the immunoglobulins from which these heavy chains are derived exhibit binding activity for various haptens. The differing hapten specificities are closely correlated with distinct primary amino-acid sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215076"} {"pmid": "4215077", "title": "Deficiencies or excesses of metabolites interfering with differentiation.", "content": "Deficiencies or excesses of metabolites interfering with differentiation. Auxotrophic mutants of Bacillus subtilis need much higher concentrations of the required adenine, nicotinic acid, riboflavin, thiamine, or tryptophan for optimal sporulation than for maximal growth. Acetate can partially replace thiamine, indicating the importance of the pyruvate dehydrogenase system for differentiation. A glycerol-requiring mutant can sporulate only if its cells contain a small concentration of L-alpha-glycerol phosphate during development. This can best be achieved by excess (>/=5 mM) of extracellular alpha-glycerol phosphate, which enters B. subtilis very slowly. The results show that both biosynthetic and catabolic enzymes are often needed to maintain the precise balance of metabolites required for differentiation. Mutants unable to catabolize fructose 6-phosphate, glucose 6-phosphate, or alpha-glycerol phosphate do not sporulate as long as these compounds accumulate inside the cells; their development is blocked before prespore septa have formed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215077"} {"pmid": "4215078", "title": "Highly purified colicin E3 contains immunity protein.", "content": "Highly purified colicin E3 contains immunity protein. Colicin E3, even when highly purified, still contains about one molar equivalent of a second protein, \"E3 immunity protein.\" The two proteins are bound together in a complex that can be dissociated only under strongly denaturing conditions, such as electrophoresis in sodium dodecyl sulfate-polyacrylamide gles or by gel filtration in 6 M guanidine.hydrochloride. Colicin and immunity protein were separated by preparative electrophoresis in sodium dodecyl sulfate-polyacrylamide gels. The immunity protein prepared in this way was shown to be functionally and immunologically identical to immunity protein purified from colicinogenic cells by other methods. Colicin E3 that had been freed of immunity protein was much more active than complexed colicin in inhibiting protein synthesis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215078"} {"pmid": "4215080", "title": "The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution.", "content": "The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution. The structural analysis of the Fab' fragment of human myeloma immunoglobulin IgGl(lambda) New has been extended to a nominal resolution of 2.0 A. Each of the structural subunits corresponding to the variable and to the constant homology regions of the light and heavy chains contains two irregular beta-sheets which are roughly parallel to each other and surround a tightly packed interior of hydrophobic side chains. About 50-60% of the amino-acid residues are included in beta-pleated sheets. Sequence alignments between the homology regions of Fab' New obtained by comparison of their three-dimensional structures are given. Some of the sequence variations observed in light and heavy chains and the role of the regions of hypervariable sequence in defining the size and shape of the active site of different immunoglobulin molecules are discussed on the basis of the three-dimensional model of Fab' New.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215080"} {"pmid": "4215079", "title": "Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.", "content": "Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Arachidonic acid incubated with human platelets was converted into three compounds, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, 12L-hydroxy-5,8,10-heptadecatrienoic acid, and the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12L-dihydroxy-5,10-heptadecadienoic acid. The formation of the two latter compounds from arachidonic acid proceeded by pathways involving the enzyme, fatty acid cyclo-oxygenase, in the initial step and with the prostaglandin endoperoxide, PGG(2), as an intermediate. The first mentioned compound was formed from 12L-hydroperoxy-5,8,10,14-eicosatetraenoic acid, which in turn was formed from arachidonic acid by the action of a novel lipoxygenase. Aspirin and indomethacin inhibited the fatty acid cyclo-oxygenase but not the lipoxygenase, whereas 5,8,11,14-eicosatetraynoic acid inhibited both enzymes. The almost exclusive transformation of the endoperoxide structure into non-prostaglandin derivatives supports the hypothesis that the endoperoxides can participate directly and not by way of the classical prostaglandins in regulation of cell functions. The observed transformations of arachidonic acid in platelets also explain the aggregating effect of this acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215079"} {"pmid": "4215081", "title": "The localization of transfer RNA5Lys genes in Drosophila melanogaster.", "content": "The localization of transfer RNA5Lys genes in Drosophila melanogaster. Transfer RNA(5) (Lys) was isolated and purified from Drosophila melanogaster. It was iodinated in vitro with sodium [(125)I]iodide and hybridized in situ to the polytene salivary gland chromosomes from Drosophila. Autoradiographs exposed three to four weeks allowed the localization of this tRNA to the right arm of chromosome 2 between bands 48F and 49A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215081"} {"pmid": "4215082", "title": "Prostaglandin synthetase system--resolution into oxygenase and isomerase components.", "content": "Prostaglandin synthetase system--resolution into oxygenase and isomerase components. The microsomal fraction of bovine vesicular gland catalyzed the conversion of [1-(14)C]8,11,14-eicosatrienoic acid to prostaglandin E(1) in the presence of tryptophan, hemoglobin, and glutathione. The prostaglandin synthetase system was solubilized by treatment of the microsomal fraction with Tween 20 in the presence of ethylene glycol. DEAE-cellulose column chromatography separated the enzyme into two fractions (Fractions I and II), both of which were required for prostaglandin E(1) synthesis. When Fraction I alone was incubated with 8,11,14-eicosatrienoic acid, an unstable compound accumulated. This compound was converted to prostaglandin E(1) by the addition of Fraction II. On the basis of its R(F) values on thin-layer chromatography, its reduction to prostaglandin F(1alpha) with stannous chloride, and the decomposition to prostaglandins F(1alpha), E(1), and D(1) at room temperature, the unstable intermediate was tentatively identified to be the 9,11-endoperoxide derivative, referred to previously as prostaglandin R(1) (Nugteren et al. (1973) Biochim. Biophys. Acta 326, 448-461) or prostaglandin H(1) (Hamberg et al. (1974) Proc. Nat. Acad. Sci. USA 71, 345-349). Of the three cofactors mentioned above, Fraction I required both tryptophan and hemoglobin, while only glutathione was necessary for Fraction II. Anti-inflammatory agents such as indomethacin and aspirin were inhibitory to Fraction I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215082"} {"pmid": "4215084", "title": "Principles of fertilization.", "content": "Principles of fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215084"} {"pmid": "4215083", "title": "Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.", "content": "Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene. Hybridization kinetic analyses with synthetic DNA indicate that there are only two to three copies of the kappa constant region gene per haploid genome. This result lends weight to the argument that the immunoglobulin light chain is encoded by more than one continuous gene sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215083"} {"pmid": "4215085", "title": "Recent research on implantation in animals.", "content": "Recent research on implantation in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215085"} {"pmid": "4215086", "title": "Effects of some amino acids on the content and uptake of histamine by neoplastic mast cells in vitro.", "content": "Effects of some amino acids on the content and uptake of histamine by neoplastic mast cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215086"} {"pmid": "4215087", "title": "Enzyme derivatives containing reactive groups. Immobilization of alpha-amylase on human erythrocytes.", "content": "Enzyme derivatives containing reactive groups. Immobilization of alpha-amylase on human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215087"} {"pmid": "4215089", "title": "Delayed pressor response to isoproterenol during alpha-adrenergic blockade.", "content": "Delayed pressor response to isoproterenol during alpha-adrenergic blockade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215089"} {"pmid": "4215088", "title": "Effect of sex and castration on hepatic and intestinal activity of drug-metabolizing enzymes.", "content": "Effect of sex and castration on hepatic and intestinal activity of drug-metabolizing enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215088"} {"pmid": "4215090", "title": "Proceedings: Behavioral effects of hypothalamic polypeptides in animals and man.", "content": "Proceedings: Behavioral effects of hypothalamic polypeptides in animals and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215090"} {"pmid": "4215091", "title": "Long-term methylphenidate treatment of hyperkinetic children.", "content": "Long-term methylphenidate treatment of hyperkinetic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215091"} {"pmid": "4215092", "title": "Long-term patients seen in an alcoholism clinic.", "content": "Long-term patients seen in an alcoholism clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215092"} {"pmid": "4215093", "title": "Letter: Insensitivity of serially transferred Tetrahymena pyriformis W. to irradiated media.", "content": "Letter: Insensitivity of serially transferred Tetrahymena pyriformis W. to irradiated media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215093"} {"pmid": "4215096", "title": "The roentgenographic manifestations of cutis laxa (generalized elastolysis).", "content": "The roentgenographic manifestations of cutis laxa (generalized elastolysis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215096"} {"pmid": "4215097", "title": "The radiographic findings in congenital cutis laxa.", "content": "The radiographic findings in congenital cutis laxa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215097"} {"pmid": "4215100", "title": "The effects of prostaglandins, prostaglandin inhibitors, and oxygen on the closure of the ductus arteriosus, pulmonary arteries and umbilical vessels in vitro.", "content": "The effects of prostaglandins, prostaglandin inhibitors, and oxygen on the closure of the ductus arteriosus, pulmonary arteries and umbilical vessels in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215100"} {"pmid": "4215109", "title": "Theileria parva: comparative infectivity of a ground tick stabilate and a classical 10-tick challenge.", "content": "Theileria parva: comparative infectivity of a ground tick stabilate and a classical 10-tick challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215109"} {"pmid": "4215110", "title": "Comparative development and evolution of the placenta in primates.", "content": "Comparative development and evolution of the placenta in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215110"} {"pmid": "4215111", "title": "Evolutionary trends in primate sex cycles.", "content": "Evolutionary trends in primate sex cycles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215111"} {"pmid": "4215113", "title": "Comparative morphology of the primate ovary.", "content": "Comparative morphology of the primate ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215113"} {"pmid": "4215102", "title": "Infections in cancer patients. I. Bacterial infections.", "content": "Infections in cancer patients. I. Bacterial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215102"} {"pmid": "4215112", "title": "Placental biosynthesis and metabolism of steroid hormones in primates.", "content": "Placental biosynthesis and metabolism of steroid hormones in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215112"} {"pmid": "4215114", "title": "Biology of primate spermatozoa.", "content": "Biology of primate spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215114"} {"pmid": "4215118", "title": "Nursing challenges: treatment and care of the patient with hyperparathyroidism.", "content": "Nursing challenges: treatment and care of the patient with hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215118"} {"pmid": "4215122", "title": "A systematic study of variables affecting protein binding of thyroxine and triiodothyronine in serum.", "content": "A systematic study of variables affecting protein binding of thyroxine and triiodothyronine in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215122"} {"pmid": "4215123", "title": "The hydrolysis of pteroylpolyglutamates in the small intestine.", "content": "The hydrolysis of pteroylpolyglutamates in the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215123"} {"pmid": "4215124", "title": "Influence of feeding and sham feeding upon serum gastrin and gastric acid secretion in control subjects and duodenal ulcer patients.", "content": "Influence of feeding and sham feeding upon serum gastrin and gastric acid secretion in control subjects and duodenal ulcer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215124"} {"pmid": "4215125", "title": "Comparison of methods to diagnose deficiency or malabsorption of vitamin B12.", "content": "Comparison of methods to diagnose deficiency or malabsorption of vitamin B12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215125"} {"pmid": "4215126", "title": "Serum B12 determination using the radiosorbent technique and the Euglena gracilis assay.", "content": "Serum B12 determination using the radiosorbent technique and the Euglena gracilis assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215126"} {"pmid": "4215127", "title": "The absorption of vitamin B12 in the blind-loop syndrome.", "content": "The absorption of vitamin B12 in the blind-loop syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215127"} {"pmid": "4215128", "title": "IgM turnover in chronic liver disease.", "content": "IgM turnover in chronic liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215128"} {"pmid": "4215121", "title": "Pathophysiology and current treatment of intestinal obstruction.", "content": "Pathophysiology and current treatment of intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215121"} {"pmid": "4215134", "title": "Notions of morality in medical organization and practice.", "content": "Notions of morality in medical organization and practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215134"} {"pmid": "4215135", "title": "Mutagens and potential mutagens in the biosphere. I. DDT and its metabolites, polychlorinated biphenyls, chlorodioxins, polycyclic aromatic hydrocarbons, haloethers.", "content": "Mutagens and potential mutagens in the biosphere. I. DDT and its metabolites, polychlorinated biphenyls, chlorodioxins, polycyclic aromatic hydrocarbons, haloethers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215135"} {"pmid": "4215136", "title": "Autoimmune haemolytic anaemia: serological and immunochemical characteristics of the autoantibodies; mechanisms of cell destruction.", "content": "Autoimmune haemolytic anaemia: serological and immunochemical characteristics of the autoantibodies; mechanisms of cell destruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215136"} {"pmid": "4215138", "title": "Studies of monkeys asphyxiated at birth: implications for minimal cerebral dysfunction.", "content": "Studies of monkeys asphyxiated at birth: implications for minimal cerebral dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215138"} {"pmid": "4215137", "title": "Autoimmune haemolytic disease in NZB mice.", "content": "Autoimmune haemolytic disease in NZB mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215137"} {"pmid": "4215139", "title": "Proliferation and maturation of bone marrow-derived lymphocytes.", "content": "Proliferation and maturation of bone marrow-derived lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215139"} {"pmid": "4215140", "title": "The identification of mouse myeloma cells which have undergone mutations in immunoglobulin production.", "content": "The identification of mouse myeloma cells which have undergone mutations in immunoglobulin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215140"} {"pmid": "4215141", "title": "Cromolyn sodium therapy in childhood asthma.", "content": "Cromolyn sodium therapy in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215141"} {"pmid": "4215142", "title": "Current diagnosis and treatment of acute pancreatitis.", "content": "Current diagnosis and treatment of acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215142"} {"pmid": "4215143", "title": "Delayed recognition of lead encephalopathy in two \"moonshine\" drinkers.", "content": "Delayed recognition of lead encephalopathy in two \"moonshine\" drinkers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215143"} {"pmid": "4215144", "title": "The Indonesian developmental area study: observations on mammals from South and East Kalimantan (Borneo).", "content": "The Indonesian developmental area study: observations on mammals from South and East Kalimantan (Borneo).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215144"} {"pmid": "4215145", "title": "Pulmonary tuberculosis in a rural area of Sarawak, Malaysia.", "content": "Pulmonary tuberculosis in a rural area of Sarawak, Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215145"} {"pmid": "4215146", "title": "Sarcocystis from rats in Sulawesi, Indonesia.", "content": "Sarcocystis from rats in Sulawesi, Indonesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215146"} {"pmid": "4215147", "title": "Observations on exflagellation of microgametocytes of Leucocytozoon sabrazesi.", "content": "Observations on exflagellation of microgametocytes of Leucocytozoon sabrazesi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215147"} {"pmid": "4215148", "title": "Leucocytozoon sabrazesi-first record from the Malayan jungle fowl, Gallus gallus spadiceus.", "content": "Leucocytozoon sabrazesi-first record from the Malayan jungle fowl, Gallus gallus spadiceus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215148"} {"pmid": "4215149", "title": "Further stages of the \"sporozoan\" from the moon rat Echinosorex gymnurus, and its possible connection with Sarcocystis.", "content": "Further stages of the \"sporozoan\" from the moon rat Echinosorex gymnurus, and its possible connection with Sarcocystis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215149"} {"pmid": "4215151", "title": "Cytological analysis of the variability of ring chromosomes in Drosophila. Communication II. Influence of temperature, the Gowen gene, and heterozygous inversion.", "content": "Cytological analysis of the variability of ring chromosomes in Drosophila. Communication II. Influence of temperature, the Gowen gene, and heterozygous inversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215151"} {"pmid": "4215150", "title": "The silvered leaf monkey as a natural host of the lung mite, Pneumonyssus simicola Banks, (Acarina: Halarachnidae) in Malaysia: a preliminary report.", "content": "The silvered leaf monkey as a natural host of the lung mite, Pneumonyssus simicola Banks, (Acarina: Halarachnidae) in Malaysia: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215150"} {"pmid": "4215152", "title": "A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication II. Interaction of the homeotic antennopedix and nasobemia genes with the polycomb, multiple sex comb, aristapedia, and thread genes.", "content": "A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication II. Interaction of the homeotic antennopedix and nasobemia genes with the polycomb, multiple sex comb, aristapedia, and thread genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215152"} {"pmid": "4215153", "title": "Investigation of the genetics of the sexual behavior of Drosophila melanogaster. Communication III. Further genetic analysis of the lines differeing in sexual activity of the males.", "content": "Investigation of the genetics of the sexual behavior of Drosophila melanogaster. Communication III. Further genetic analysis of the lines differeing in sexual activity of the males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215153"} {"pmid": "4215155", "title": "Development of mesosomes in Caryophanon.", "content": "Development of mesosomes in Caryophanon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215155"} {"pmid": "4215154", "title": "The mutagenic effect of nitrosoalkylamides on extracellular phages and bacterial transforming DNA.", "content": "The mutagenic effect of nitrosoalkylamides on extracellular phages and bacterial transforming DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215154"} {"pmid": "4215156", "title": "Letter: Intra-epithelial lymphocytes in the jejunum of malnourished children.", "content": "Letter: Intra-epithelial lymphocytes in the jejunum of malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215156"} {"pmid": "4215157", "title": "Sterilisation of laryngoscope blades. A preliminary report.", "content": "Sterilisation of laryngoscope blades. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215157"} {"pmid": "4215158", "title": "A comparison of oral feeding and total parenteral nutrition in infants of very low birthweight.", "content": "A comparison of oral feeding and total parenteral nutrition in infants of very low birthweight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215158"} {"pmid": "4215159", "title": "Intravenous fructose disappearance in protein calorie malnutrition.", "content": "Intravenous fructose disappearance in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215159"} {"pmid": "4215160", "title": "Health care and justice.", "content": "Health care and justice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215160"} {"pmid": "4215162", "title": "Blood xylose concentrations in protein energy malnutrition. Relationship to serum albumin and jejunal histology.", "content": "Blood xylose concentrations in protein energy malnutrition. Relationship to serum albumin and jejunal histology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215162"} {"pmid": "4215161", "title": "Fungi associated with common crops and crop products and their significance.", "content": "Fungi associated with common crops and crop products and their significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215161"} {"pmid": "4215163", "title": "Hypercholesterolaemia and atherosclerosis induced in vervet monkeys by cholesterol-free, semisynthetic diets.", "content": "Hypercholesterolaemia and atherosclerosis induced in vervet monkeys by cholesterol-free, semisynthetic diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215163"} {"pmid": "4215164", "title": "Controversies in the management of potentially curable breast cancer.", "content": "Controversies in the management of potentially curable breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215164"} {"pmid": "4215165", "title": "Topical burn wound therapy.", "content": "Topical burn wound therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215165"} {"pmid": "4215167", "title": "Three varieties of congenital diverticulum of the intestine.", "content": "Three varieties of congenital diverticulum of the intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215167"} {"pmid": "4215166", "title": "Interdisciplinary approach to advanced ovarian cancer.", "content": "Interdisciplinary approach to advanced ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215166"} {"pmid": "4215168", "title": "The relationship of genitourinary tract procedures and deep sepsis after total hip replacements.", "content": "The relationship of genitourinary tract procedures and deep sepsis after total hip replacements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215168"} {"pmid": "4215171", "title": "Evaluating long-term periodontal therapy.", "content": "Evaluating long-term periodontal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215171"} {"pmid": "4215172", "title": "Effect of physical activity before pregnancy on fetuses of mice exercised forcibly during pregnancy.", "content": "Effect of physical activity before pregnancy on fetuses of mice exercised forcibly during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215172"} {"pmid": "4215173", "title": "Pseudomonas aeruginosa abscess masquerading as a slowly growing solitary pulmonary nodule.", "content": "Pseudomonas aeruginosa abscess masquerading as a slowly growing solitary pulmonary nodule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215173"} {"pmid": "4215175", "title": "Maltose metabolism in diabetic state.", "content": "Maltose metabolism in diabetic state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215175"} {"pmid": "4215178", "title": "Immunological studies in patients receiving repeated allogeneic anc xenogeneic liver hemoperfusions.", "content": "Immunological studies in patients receiving repeated allogeneic anc xenogeneic liver hemoperfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215178"} {"pmid": "4215179", "title": "Lesions of bladder muscle in baboons and monkeys infected with schistosoma haematobium.", "content": "Lesions of bladder muscle in baboons and monkeys infected with schistosoma haematobium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215179"} {"pmid": "4215183", "title": "Symposium on renal lithiasis. Nutritional support of the azotemic patient.", "content": "Symposium on renal lithiasis. Nutritional support of the azotemic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215183"} {"pmid": "4215184", "title": "Hematuria in children. A guide in differential diagnosis.", "content": "Hematuria in children. A guide in differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215184"} {"pmid": "4215186", "title": "Intraprostatic injections of various antitumoral compounds into rats.", "content": "Intraprostatic injections of various antitumoral compounds into rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215186"} {"pmid": "4215177", "title": "Human hepatitis B antibody: evaluation of assays and development of a reference panel.", "content": "Human hepatitis B antibody: evaluation of assays and development of a reference panel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215177"} {"pmid": "4215187", "title": "Infection stones of prostate gland. Laboratory diagnosis and clinical management.", "content": "Infection stones of prostate gland. Laboratory diagnosis and clinical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215187"} {"pmid": "4215185", "title": "Renal function after thyroidectomy and parathyroid hormone administration. An experimental study in the pig.", "content": "Renal function after thyroidectomy and parathyroid hormone administration. An experimental study in the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215185"} {"pmid": "4215188", "title": "Syndrome of dyspraxia and multifocal seizures associated with chronic hemodialysis.", "content": "Syndrome of dyspraxia and multifocal seizures associated with chronic hemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215188"} {"pmid": "4215189", "title": "Long-term membrane oxygenation without systemic heparinization.", "content": "Long-term membrane oxygenation without systemic heparinization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215189"} {"pmid": "4215190", "title": "Preliminary studies with the fistula catheter - a new vascular access prosthesis.", "content": "Preliminary studies with the fistula catheter - a new vascular access prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215190"} {"pmid": "4215176", "title": "A method for serial measurement of regional cortical metabolism and blood flow.", "content": "A method for serial measurement of regional cortical metabolism and blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215176"} {"pmid": "4215191", "title": "Coated adsorbents for direct blood perfusion II.", "content": "Coated adsorbents for direct blood perfusion II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215191"} {"pmid": "4215193", "title": "Fundamental biophysical aspects of high-energy radiations in cancer therapy.", "content": "Fundamental biophysical aspects of high-energy radiations in cancer therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215193"} {"pmid": "4215192", "title": "A new technique employing extracorporeal chemotherapy.", "content": "A new technique employing extracorporeal chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215192"} {"pmid": "4215205", "title": "An unidentified sporozoan encephalomyelitis in sheep.", "content": "An unidentified sporozoan encephalomyelitis in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215205"} {"pmid": "4215207", "title": "Spontaneous malignant lymphoma in a new-world primate.", "content": "Spontaneous malignant lymphoma in a new-world primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215207"} {"pmid": "4215206", "title": "Ultrastructural studies of spleens, brains, and brain cell cultures of mice with scrapie.", "content": "Ultrastructural studies of spleens, brains, and brain cell cultures of mice with scrapie.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215206"} {"pmid": "4215208", "title": "Toxoplasma-like encephalomyelitis in the horse.", "content": "Toxoplasma-like encephalomyelitis in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215208"} {"pmid": "4215209", "title": "Quantitative studies on serum immunoglobulin levels in suckled calves from birth to five weeks.", "content": "Quantitative studies on serum immunoglobulin levels in suckled calves from birth to five weeks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215209"} {"pmid": "4215210", "title": "Brucellosis in wildlife.", "content": "Brucellosis in wildlife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215210"} {"pmid": "4215211", "title": "Brucella abortus biotype 3 in Tanzania.", "content": "Brucella abortus biotype 3 in Tanzania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215211"} {"pmid": "4215213", "title": "Serological relationship between maize rough dwarf virus and rice black-streaked dwarf virus.", "content": "Serological relationship between maize rough dwarf virus and rice black-streaked dwarf virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215213"} {"pmid": "4215212", "title": "In vitro interaction between phage and receptor lipopolysaccharide: a novel glycosidase associated with Salmonella phage epsilon15.", "content": "In vitro interaction between phage and receptor lipopolysaccharide: a novel glycosidase associated with Salmonella phage epsilon15.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215212"} {"pmid": "4215215", "title": "Low-frequency specialized transduction with Bacillus subtilis bacteriophage phi 105.", "content": "Low-frequency specialized transduction with Bacillus subtilis bacteriophage phi 105.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215215"} {"pmid": "4215214", "title": "Detection of mycoviruses using antiserum specific for dsRNA.", "content": "Detection of mycoviruses using antiserum specific for dsRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215214"} {"pmid": "4215216", "title": "Bacteriophage gene expression in sporulating cells of Bacillus subtilis 168.", "content": "Bacteriophage gene expression in sporulating cells of Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215216"} {"pmid": "4215217", "title": "Isolation and genetic mapping of temperature-sensitive mutants of cyanophage LPP2-SPI.", "content": "Isolation and genetic mapping of temperature-sensitive mutants of cyanophage LPP2-SPI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215217"} {"pmid": "4215218", "title": "Spectral sensitivity of the short wavelength mechanism in the squirrel monkey visual system.", "content": "Spectral sensitivity of the short wavelength mechanism in the squirrel monkey visual system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215218"} {"pmid": "4215219", "title": "Inhibition of toad (Bufo bufo L) retinal on-off and off-ganglion cells via active eye closing.", "content": "Inhibition of toad (Bufo bufo L) retinal on-off and off-ganglion cells via active eye closing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215219"} {"pmid": "4215231", "title": "Old age--a problem for society as a whole.", "content": "Old age--a problem for society as a whole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215231"} {"pmid": "4215239", "title": "Total parenteral alimentation.", "content": "Total parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215239"} {"pmid": "4215240", "title": "Gonorrhea from birth through adolescence: local and systemic manifestations.", "content": "Gonorrhea from birth through adolescence: local and systemic manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215240"} {"pmid": "4215242", "title": "The conjugation of indolylacetic acid in man, monkeys and other species.", "content": "The conjugation of indolylacetic acid in man, monkeys and other species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215242"} {"pmid": "4215243", "title": "Rapid differentiation of certain bacteria in mixed populations by gas-liquid chromatography.", "content": "Rapid differentiation of certain bacteria in mixed populations by gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215243"} {"pmid": "4215248", "title": "Studies on the methodical and biological variation of proteins quantitated by single radial immunodiffusion.", "content": "Studies on the methodical and biological variation of proteins quantitated by single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215248"} {"pmid": "4215256", "title": "Interaction of nutrition and infection: Trypanosoma lewisi, folic acid levels in sera and tissues of normal and folic acid-deficient rats.", "content": "Interaction of nutrition and infection: Trypanosoma lewisi, folic acid levels in sera and tissues of normal and folic acid-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215256"} {"pmid": "4215263", "title": "The isoenzymes of lactate dehydrogenase of bovine thrombocytes.", "content": "The isoenzymes of lactate dehydrogenase of bovine thrombocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215263"} {"pmid": "4215264", "title": "Developmental biochemistry of bovine foetal muscle. II. Collagen.", "content": "Developmental biochemistry of bovine foetal muscle. II. Collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215264"} {"pmid": "4215266", "title": "Studies on the effect of temperature and glycerol on the inactivation of the virus of haemorrhagic septicaemia (VHS) of rainbow trout by use of the microtiter system.", "content": "Studies on the effect of temperature and glycerol on the inactivation of the virus of haemorrhagic septicaemia (VHS) of rainbow trout by use of the microtiter system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215266"} {"pmid": "4215269", "title": "Control of Pseudomonas aeruginosa infections.", "content": "Control of Pseudomonas aeruginosa infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215269"} {"pmid": "4215271", "title": "Immunoglobulins G, A, and M in bronchial asthma.", "content": "Immunoglobulins G, A, and M in bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215271"} {"pmid": "4215272", "title": "Bronchial reactivity to inhaled histamine in asthmatic patients, before and after administration of atropine, phentolamine or disodium cromoglycate.", "content": "Bronchial reactivity to inhaled histamine in asthmatic patients, before and after administration of atropine, phentolamine or disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215272"} {"pmid": "4215273", "title": "New developments in asthma therapy.", "content": "New developments in asthma therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215273"} {"pmid": "4215274", "title": "Selection of patients for cromolyn therapy.", "content": "Selection of patients for cromolyn therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215274"} {"pmid": "4215275", "title": "Environmental factors and host responses in asthma.", "content": "Environmental factors and host responses in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215275"} {"pmid": "4215277", "title": "Fine structural localization of alkaline phosphatase activity of the female genital canal surface during the estrous cycle and after castration in rats.", "content": "Fine structural localization of alkaline phosphatase activity of the female genital canal surface during the estrous cycle and after castration in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215277"} {"pmid": "4215276", "title": "Comparative nitrogen balance studies with an amino-acid solution based on nutritional studies against two protein-based solutions.", "content": "Comparative nitrogen balance studies with an amino-acid solution based on nutritional studies against two protein-based solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215276"} {"pmid": "4215278", "title": "Cystine: a semi-essential amino acid in the newborn infant.", "content": "Cystine: a semi-essential amino acid in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215278"} {"pmid": "4215279", "title": "Resting metabolic rate in malnourished babies in relation to total body potassium.", "content": "Resting metabolic rate in malnourished babies in relation to total body potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215279"} {"pmid": "4215270", "title": "Onset of diabetic ketoacidosis with symptoms of acute abdomen during oral mestranol treatment.", "content": "Onset of diabetic ketoacidosis with symptoms of acute abdomen during oral mestranol treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215270"} {"pmid": "4215281", "title": "The isolation of Mycoplasma primatum during an autopsy study of the mycoplasma flora of the human urinary tract.", "content": "The isolation of Mycoplasma primatum during an autopsy study of the mycoplasma flora of the human urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215281"} {"pmid": "4215280", "title": "Pseudomonas aeruginosa infection in cystic fibrosis. Occurrence of precipitating antibodies against pseudomonas aeruginosa in relation to the concentration of sixteen serum proteins and the clinical and radiographical status of the lungs.", "content": "Pseudomonas aeruginosa infection in cystic fibrosis. Occurrence of precipitating antibodies against pseudomonas aeruginosa in relation to the concentration of sixteen serum proteins and the clinical and radiographical status of the lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215280"} {"pmid": "4215282", "title": "Mutations in Arthrobacter affecting formation of extracellular protease.", "content": "Mutations in Arthrobacter affecting formation of extracellular protease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215282"} {"pmid": "4215283", "title": "Infection of Arvicola terrestris (vole rat) with M. tuberculosis and M. bovis.", "content": "Infection of Arvicola terrestris (vole rat) with M. tuberculosis and M. bovis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215283"} {"pmid": "4215284", "title": "Antimycobacterial antibodies in sera from patients throughout the clinico-pathological disease spectrum of leprosy.", "content": "Antimycobacterial antibodies in sera from patients throughout the clinico-pathological disease spectrum of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215284"} {"pmid": "4215285", "title": "Determination of antistreptolysin O by reversed single radial immunodiffusion.", "content": "Determination of antistreptolysin O by reversed single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215285"} {"pmid": "4215287", "title": "DDT and related substances: effects on permeability properties of myelinated xenopus nerve fibre. Potential clamp analysis.", "content": "DDT and related substances: effects on permeability properties of myelinated xenopus nerve fibre. Potential clamp analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215287"} {"pmid": "4215290", "title": "Study of lysogenic Bacillus cereus strains by electron microscopy.", "content": "Study of lysogenic Bacillus cereus strains by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215290"} {"pmid": "4215289", "title": "(14C)adenine uptake into Bacillus anthracis adenylsuccinate lyase deficient mutant.", "content": "(14C)adenine uptake into Bacillus anthracis adenylsuccinate lyase deficient mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215289"} {"pmid": "4215291", "title": "A highly specific phage attacking Bacillus anthracis strain Sterne.", "content": "A highly specific phage attacking Bacillus anthracis strain Sterne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215291"} {"pmid": "4215292", "title": "Bacteriological and pharmacological investigations with Garamycin (gentamicin).", "content": "Bacteriological and pharmacological investigations with Garamycin (gentamicin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215292"} {"pmid": "4215293", "title": "Study of auxotroph mutants induced by copper sulphate in Bacillus subtilis.", "content": "Study of auxotroph mutants induced by copper sulphate in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215293"} {"pmid": "4215294", "title": "Bacterial contamination and sparing heat treatment of mother's milk.", "content": "Bacterial contamination and sparing heat treatment of mother's milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215294"} {"pmid": "4215295", "title": "Topologic analysis of the fate of transfecting SP50 DNA in competent cells of Bacillus subtilis.", "content": "Topologic analysis of the fate of transfecting SP50 DNA in competent cells of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215295"} {"pmid": "4215296", "title": "Pirazocillin: a new acid and penicillinase resistant semisynthetic penicillin.", "content": "Pirazocillin: a new acid and penicillinase resistant semisynthetic penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215296"} {"pmid": "4215299", "title": "Physicochemical studies of Ca++ controlled antigen antibody systems.", "content": "Physicochemical studies of Ca++ controlled antigen antibody systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215299"} {"pmid": "4215298", "title": "13C NMR studies of the interaction of Hb and carbonic anhydrase with 13Co2.", "content": "13C NMR studies of the interaction of Hb and carbonic anhydrase with 13Co2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215298"} {"pmid": "4215301", "title": "The application of perturbed directional correlation of gamma rays to the study of protein-metal interactions.", "content": "The application of perturbed directional correlation of gamma rays to the study of protein-metal interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215301"} {"pmid": "4215300", "title": "The functional roles of metals in metalloenzymes.", "content": "The functional roles of metals in metalloenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215300"} {"pmid": "4215302", "title": "Nutrition and malnutrition. Identification and measurement. Definition of the problem.", "content": "Nutrition and malnutrition. Identification and measurement. Definition of the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215302"} {"pmid": "4215303", "title": "Anthropometry as an index of nutritional status.", "content": "Anthropometry as an index of nutritional status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215303"} {"pmid": "4215305", "title": "Relative values of longitudinal, cross-sectional and mixed data collection in community studies.", "content": "Relative values of longitudinal, cross-sectional and mixed data collection in community studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215305"} {"pmid": "4215304", "title": "From a QUAC stick to a compositional assessment of man's nutritional status.", "content": "From a QUAC stick to a compositional assessment of man's nutritional status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215304"} {"pmid": "4215306", "title": "Ecological factors relating to child growth and nutritional status.", "content": "Ecological factors relating to child growth and nutritional status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215306"} {"pmid": "4215307", "title": "Behavioral effects of artificial gravity: equivalence of rotation rate and radius in controlling gravity-avoidance behavior.", "content": "Behavioral effects of artificial gravity: equivalence of rotation rate and radius in controlling gravity-avoidance behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215307"} {"pmid": "4215308", "title": "Coprophagy in laboratory animals: a preliminary study to assess potential influences of excreta ingestion on radionuclide retention patterns.", "content": "Coprophagy in laboratory animals: a preliminary study to assess potential influences of excreta ingestion on radionuclide retention patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215308"} {"pmid": "4215309", "title": "Letter: Heat stability of serum pyridoxal.", "content": "Letter: Heat stability of serum pyridoxal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215309"} {"pmid": "4215311", "title": "Special problems associated with the isolation and identification of intestinal bacteria in fecal flora studies.", "content": "Special problems associated with the isolation and identification of intestinal bacteria in fecal flora studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215311"} {"pmid": "4215310", "title": "A comparison of methods for estimating human body composition.", "content": "A comparison of methods for estimating human body composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215310"} {"pmid": "4215312", "title": "A new method for determination of alpha-1-antitrypsin phenotypes using isoelectric focusing on polyacrylamide gel slabs.", "content": "A new method for determination of alpha-1-antitrypsin phenotypes using isoelectric focusing on polyacrylamide gel slabs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215312"} {"pmid": "4215313", "title": "Demonstration of IgE on human-skin mast cells using anti-IgE125I and refined light microscopy.", "content": "Demonstration of IgE on human-skin mast cells using anti-IgE125I and refined light microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215313"} {"pmid": "4215314", "title": "Effect of incubation time on Lactobacillus casei bioassay. Variation with two different commercial assay media.", "content": "Effect of incubation time on Lactobacillus casei bioassay. Variation with two different commercial assay media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215314"} {"pmid": "4215315", "title": "Parenteral hyperalimentation--Five years' clinical experience.", "content": "Parenteral hyperalimentation--Five years' clinical experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215315"} {"pmid": "4215316", "title": "Letter: Trace element requirements in hyperalimentation.", "content": "Letter: Trace element requirements in hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215316"} {"pmid": "4215317", "title": "Letter: Stability of phytonadione in hyperalimentation fluids.", "content": "Letter: Stability of phytonadione in hyperalimentation fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215317"} {"pmid": "4215318", "title": "Correlation of low serum IgM levels with absence of functional splenic tissue in sickle cell disease syndromes.", "content": "Correlation of low serum IgM levels with absence of functional splenic tissue in sickle cell disease syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215318"} {"pmid": "4215319", "title": "Discoid lupus erythematosus with macroglobulinemia. Correlations between autoimmunity and B cell malignancy with hyperimmunoglobulinemia.", "content": "Discoid lupus erythematosus with macroglobulinemia. Correlations between autoimmunity and B cell malignancy with hyperimmunoglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215319"} {"pmid": "4215320", "title": "Arthritis in acute hepatitis and chronic active hepatitis. Pathology of the synovial membrane with evidence for the presence of Australia antigen in synovial membranes.", "content": "Arthritis in acute hepatitis and chronic active hepatitis. Pathology of the synovial membrane with evidence for the presence of Australia antigen in synovial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215320"} {"pmid": "4215321", "title": "Familial myeloma. Report of eight families and a study of serum proteins in their relatives.", "content": "Familial myeloma. Report of eight families and a study of serum proteins in their relatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215321"} {"pmid": "4215322", "title": "Epidemic viral hepatitis, type B, in hospital personnel.", "content": "Epidemic viral hepatitis, type B, in hospital personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215322"} {"pmid": "4215323", "title": "Auto-immune hemolytic anemia.", "content": "Auto-immune hemolytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215323"} {"pmid": "4215324", "title": "Crisis intervention for ghetto children: contraindications and alternative considerations.", "content": "Crisis intervention for ghetto children: contraindications and alternative considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215324"} {"pmid": "4215325", "title": "Time course of isotonic contraction in single cells and muscle strips from Bufo marinus stomach.", "content": "Time course of isotonic contraction in single cells and muscle strips from Bufo marinus stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215325"} {"pmid": "4215326", "title": "Absence of edge damage in toad urinary bladder.", "content": "Absence of edge damage in toad urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215326"} {"pmid": "4215327", "title": "Effects of stimulus conditions, temperature, and length on energy output of frog and toad sartorius.", "content": "Effects of stimulus conditions, temperature, and length on energy output of frog and toad sartorius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215327"} {"pmid": "4215328", "title": "Letter: Dominance, sexual preference, and sexism.", "content": "Letter: Dominance, sexual preference, and sexism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215328"} {"pmid": "4215329", "title": "Influence of fractionation on acute and late reactions in vocal cord carcinoma.", "content": "Influence of fractionation on acute and late reactions in vocal cord carcinoma. Four schedules for the treatment of localized vocal cord carcinoma were compared, to establish a relationship between daily and total dose, and acute and late normal tissue reactions. All patients were treated 5 days per week. All of those who received 200 R daily (6,000 R in 30 treatments) developed a confluent mucositis and minimal to moderate subsequent aryepiglottic edema. Patients who received 180 R daily (6,480 R in 36 treatments) developed a patchy mucositis. Those who received 170 R daily (7,140 R or 6,400 rads in 42 treatments) developed only a brisk erythema, with decreasing incidence and severity of edema. At 160 R daily (6,880 R in 43 treatments) only a mild erythema developed, with no visible edema at any time. Local recurrence rates of about 10 percent for T1 lesions, and of about 25 per cent for T2 and T3 lesions, indicate that the decrease in reactions with longer fractionation has been achieved without loss of tumor control. Even minimal improvement in functional status following treatment for this highly curable malignancy well justifies the inconvenience of the increased number of treatments. The present formula of Ellis for normal tissue tolerance is not consistent with these findings, since the NSDs are essentially identical for all 4 schedules, while tolerance is notably improved by increasing fractionation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215329"} {"pmid": "4215330", "title": "Kaposi's sarcoma. Experience with ten cases.", "content": "Kaposi's sarcoma. Experience with ten cases. Kaposi's sarcoma is uncommon in the U.S.A. and common in Africa. Men are affected at least 4 times more frequently than females. It occurs simultaneously with lymphomas and resembles them in several ways. Radiation therapy controls the disease well. Ten patients were seen with the disease. Most had a relatively benign course, especially the 4 women. Treatment with supervoltage irradiation and cryosurgery was effective in controlling local disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215330"} {"pmid": "4215331", "title": "Computer generated isodose curves for high energy x-ray machines. Experimental verification and time-saving strategies.", "content": "Computer generated isodose curves for high energy x-ray machines. Experimental verification and time-saving strategies. Calculation of isodose patterns for high energy therapy units using Cunningham's BEAM program requires accurate information on the beam profile in air. This may be obtained by scanning across the x-ray beam using a very small silicon diode detector. Data obtained on a particular unit may not be applicable to any other unit. Computer calculations of isodose curves for high energy x-ray machines must use a 0.25 cm. or smaller lateral grid of dose calculation points to ensure accurate reproduction of the sharp fall-off of the dose at the beam edge. Computer calculation time to obtain the isodose curves using this size lateral grid is prohibitively long. The computing time can be appreciably reduced by: (1) changing the width of the annular sectors used in calculating the contribution of scattered radiation to the dose to 0.5 cm.; and (2) calculating the dose at 0.25 cm. lateral intervals within 1 cm. of the beam edge, but changing the spacing of the grid to 1 cm. inside the field. These programming strategies do not produce any significant change in the isodose curves but lead to a significant reduction in computer time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215331"} {"pmid": "4215332", "title": "Design of X-ray targets for high energy linear accelerators in radiotherapy.", "content": "Design of X-ray targets for high energy linear accelerators in radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215332"} {"pmid": "4215334", "title": "Schistosoma mansoni circulating antigen: detection by complement fixation in sera from infected hamsters and mice.", "content": "Schistosoma mansoni circulating antigen: detection by complement fixation in sera from infected hamsters and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215334"} {"pmid": "4215333", "title": "Angiographic features of arterial lesions in neurofibromatosis.", "content": "Angiographic features of arterial lesions in neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215333"} {"pmid": "4215335", "title": "Late assessment of results of cricopharyngeal myotomy for cervical dysphagia.", "content": "Late assessment of results of cricopharyngeal myotomy for cervical dysphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215335"} {"pmid": "4215337", "title": "Pyrexia following open heart surgery. The role of bacterial infection.", "content": "Pyrexia following open heart surgery. The role of bacterial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215337"} {"pmid": "4215336", "title": "Use of tobramycin in eradicating experimental bacterial endophthalmitis.", "content": "Use of tobramycin in eradicating experimental bacterial endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215336"} {"pmid": "4215338", "title": "Removal of proteases from DNase I by chromatography over agarose with covalently attached lima bean protease inhibitor.", "content": "Removal of proteases from DNase I by chromatography over agarose with covalently attached lima bean protease inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215338"} {"pmid": "4215340", "title": "The determination of chlorine in organic materials by combustion and microcoulometry.", "content": "The determination of chlorine in organic materials by combustion and microcoulometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215340"} {"pmid": "4215339", "title": "Anomalous behaviour of EDTA during gel filtration. Studies on the possible contamination of the S100 protein.", "content": "Anomalous behaviour of EDTA during gel filtration. Studies on the possible contamination of the S100 protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215339"} {"pmid": "4215341", "title": "Synthesis of the active derivative of bovine trypsin-kallikrein inhibitor (Kunitz) with open peptide bond in the reactive site.", "content": "Synthesis of the active derivative of bovine trypsin-kallikrein inhibitor (Kunitz) with open peptide bond in the reactive site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215341"} {"pmid": "4215342", "title": "Proteinase catalyzed resynthesis of the peptide bond Lys 15--Ala 16 in the derivative of trypsin-kallikrein inhibitor (Kunitz) with this peptide bond hydrolyzed.", "content": "Proteinase catalyzed resynthesis of the peptide bond Lys 15--Ala 16 in the derivative of trypsin-kallikrein inhibitor (Kunitz) with this peptide bond hydrolyzed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215342"} {"pmid": "4215343", "title": "Replacement of lysine by arginine, phenylalanine, and tryptophan in the reactive site of the trypsin-kallikrein inhibitor (Kunitz).", "content": "Replacement of lysine by arginine, phenylalanine, and tryptophan in the reactive site of the trypsin-kallikrein inhibitor (Kunitz).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215343"} {"pmid": "4215344", "title": "Inactivation of the trypsin-kallikrein inhibitor (Kunitz) by cleavage of the dipeptide Ala 16--Arg 17 in the reactive site.", "content": "Inactivation of the trypsin-kallikrein inhibitor (Kunitz) by cleavage of the dipeptide Ala 16--Arg 17 in the reactive site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215344"} {"pmid": "4215345", "title": "Evaluation of agar gel immunodiffusion for detection of immunologic response of pigs to experimental infection with hemagglutinating encephalomyelitis virus.", "content": "Evaluation of agar gel immunodiffusion for detection of immunologic response of pigs to experimental infection with hemagglutinating encephalomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215345"} {"pmid": "4215346", "title": "Intestinal absorption of D-xylose and folic acid measured by a perfusion technique in patas monkeys (Erythrocebus patas).", "content": "Intestinal absorption of D-xylose and folic acid measured by a perfusion technique in patas monkeys (Erythrocebus patas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215346"} {"pmid": "4215347", "title": "Epidemiologic studies relating thermophilic fungi and hypersensitivity lung syndromes.", "content": "Epidemiologic studies relating thermophilic fungi and hypersensitivity lung syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215347"} {"pmid": "4215348", "title": "The purification of mycobacterial polysaccharides with concanavalin A.", "content": "The purification of mycobacterial polysaccharides with concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215348"} {"pmid": "4215349", "title": "Letter: The impact of chemotherapy on the care of patients with tuberculosis.", "content": "Letter: The impact of chemotherapy on the care of patients with tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215349"} {"pmid": "4215350", "title": "Active and passive immunization in the treatment of experimental burn wound sepsis from Pseudomonas.", "content": "Active and passive immunization in the treatment of experimental burn wound sepsis from Pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215350"} {"pmid": "4215351", "title": "Group-y meningococcal disease. Twelve cases at an army training center.", "content": "Group-y meningococcal disease. Twelve cases at an army training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215351"} {"pmid": "4215352", "title": "Treatment of diphtheria carriers: benzathine penicillin, erythromycin, and clindamycin.", "content": "Treatment of diphtheria carriers: benzathine penicillin, erythromycin, and clindamycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215352"} {"pmid": "4215353", "title": "Letter: Variant anginal syndrome, coronary artery spasm, and ventricular fibrillation in absence of chest pain.", "content": "Letter: Variant anginal syndrome, coronary artery spasm, and ventricular fibrillation in absence of chest pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215353"} {"pmid": "4215355", "title": "Comparative structure of myoglobin: primates and tree-shrew.", "content": "Comparative structure of myoglobin: primates and tree-shrew.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215355"} {"pmid": "4215357", "title": "Rodent hemoglobin structure: a comparison of several species of mice.", "content": "Rodent hemoglobin structure: a comparison of several species of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215357"} {"pmid": "4215356", "title": "Multiple hemoglobin alpha-chain loci in monkeys, apes, and man.", "content": "Multiple hemoglobin alpha-chain loci in monkeys, apes, and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215356"} {"pmid": "4215358", "title": "Exploratory studies on detection of hemoglobins in the early human fetus in utero.", "content": "Exploratory studies on detection of hemoglobins in the early human fetus in utero.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215358"} {"pmid": "4215359", "title": "Effects of membrane potential on sodium and potassium fluxes in squid axons.", "content": "Effects of membrane potential on sodium and potassium fluxes in squid axons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215359"} {"pmid": "4215360", "title": "A delayed side effect of topical thiotepa.", "content": "A delayed side effect of topical thiotepa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215360"} {"pmid": "4215364", "title": "Space microbiology.", "content": "Space microbiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215364"} {"pmid": "4215366", "title": "Persisting bacteriophage infections, lysogeny, and phage conversions.", "content": "Persisting bacteriophage infections, lysogeny, and phage conversions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215366"} {"pmid": "4215365", "title": "Viroids: the smallest known agents of infectious disease.", "content": "Viroids: the smallest known agents of infectious disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215365"} {"pmid": "4215367", "title": "Virus-induced modification of cellular membranes related to viral structure.", "content": "Virus-induced modification of cellular membranes related to viral structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215367"} {"pmid": "4215368", "title": "Mechanisms of inorganic oxidation and energy coupling.", "content": "Mechanisms of inorganic oxidation and energy coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215368"} {"pmid": "4215370", "title": "An immunological and electrophoretic study of Rhodospirillum rubrum chromatophore fragments.", "content": "An immunological and electrophoretic study of Rhodospirillum rubrum chromatophore fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215370"} {"pmid": "4215372", "title": "Proceedings: Parenteral feeding: metabolic changes.", "content": "Proceedings: Parenteral feeding: metabolic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215372"} {"pmid": "4215371", "title": "Calorimetric measurement of the enthalpy of magnesium binding to yeast enolase.", "content": "Calorimetric measurement of the enthalpy of magnesium binding to yeast enolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215371"} {"pmid": "4215363", "title": "Clinical diagnosis of the monoclonal gammopathies.", "content": "Clinical diagnosis of the monoclonal gammopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215363"} {"pmid": "4215373", "title": "Proceedings: Parenteral feeding: surgical indications and techniques.", "content": "Proceedings: Parenteral feeding: surgical indications and techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215373"} {"pmid": "4215374", "title": "Proceedings: Use of diphosphonates in diseases associated with ectopic calcification.", "content": "Proceedings: Use of diphosphonates in diseases associated with ectopic calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215374"} {"pmid": "4215375", "title": "Polychlorinated biphenyls. Storage, distribution, excretion, and recovery: liver morphology after prolonged dietary ingestion.", "content": "Polychlorinated biphenyls. Storage, distribution, excretion, and recovery: liver morphology after prolonged dietary ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215375"} {"pmid": "4215362", "title": "A reference blood as a control of parameters in Coulter S.", "content": "A reference blood as a control of parameters in Coulter S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215362"} {"pmid": "4215378", "title": "Atherosclerotic coronary artery aneurysm. Report of five cases and review of literature.", "content": "Atherosclerotic coronary artery aneurysm. Report of five cases and review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215378"} {"pmid": "4215377", "title": "Disseminated toxoplasmosis in the compromised host. A report of five cases.", "content": "Disseminated toxoplasmosis in the compromised host. A report of five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215377"} {"pmid": "4215379", "title": "Prolonged trance-like stupor in epilepsy. Petit mal status-wave stupor, spaced-out status.", "content": "Prolonged trance-like stupor in epilepsy. Petit mal status-wave stupor, spaced-out status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215379"} {"pmid": "4215380", "title": "Gonococcal lymphadenitis.", "content": "Gonococcal lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215380"} {"pmid": "4215394", "title": "One-step isolation of microbial ribulose-1,5-diphosphate carboxylase.", "content": "One-step isolation of microbial ribulose-1,5-diphosphate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215394"} {"pmid": "4215395", "title": "Estimation of the genome size of blue-green algae from DNA renaturation rates.", "content": "Estimation of the genome size of blue-green algae from DNA renaturation rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215395"} {"pmid": "4215396", "title": "Studies on gliding motility in Myxococcus xanthus.", "content": "Studies on gliding motility in Myxococcus xanthus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215396"} {"pmid": "4215400", "title": "Immunochemical determination of human pregnancy proteins.", "content": "Immunochemical determination of human pregnancy proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215400"} {"pmid": "4215401", "title": "Distribution of gastrin in human digestive organs demonstrated by direct immunofluorescence.", "content": "Distribution of gastrin in human digestive organs demonstrated by direct immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215401"} {"pmid": "4215403", "title": "Nursing care of the patient being maintained on long-term peritoneal dialysis.", "content": "Nursing care of the patient being maintained on long-term peritoneal dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215403"} {"pmid": "4215405", "title": "Retina and optic nerve after posterior ciliary artery occlusion. An experimental study in squirrel monkeys.", "content": "Retina and optic nerve after posterior ciliary artery occlusion. An experimental study in squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215405"} {"pmid": "4215406", "title": "Effect of lidocaine on the antibacterial activity of seven antibiotics.", "content": "Effect of lidocaine on the antibacterial activity of seven antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215406"} {"pmid": "4215407", "title": "Ocular manifestations of Conradi disease.", "content": "Ocular manifestations of Conradi disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215407"} {"pmid": "4215408", "title": "TheThe genetic architecture of resistance to desiccation in populations of Drosophila melanogaster and D. simulans.", "content": "TheThe genetic architecture of resistance to desiccation in populations of Drosophila melanogaster and D. simulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215408"} {"pmid": "4215409", "title": "Drinks, drugs - the doctor's dilemma.", "content": "Drinks, drugs - the doctor's dilemma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215409"} {"pmid": "4215410", "title": "A new look at an age old problem.", "content": "A new look at an age old problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215410"} {"pmid": "4215413", "title": "Preprogrammed and feedback-guided movements of monkeys.", "content": "Preprogrammed and feedback-guided movements of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215413"} {"pmid": "4215414", "title": "Genetic control of activity, preening, and the response to a shadow stimulus in Drosophila melanogaster.", "content": "Genetic control of activity, preening, and the response to a shadow stimulus in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215414"} {"pmid": "4215415", "title": "Recommended methods used in the nutritional status assessment: clinical signs and symptoms.", "content": "Recommended methods used in the nutritional status assessment: clinical signs and symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215415"} {"pmid": "4215416", "title": "Reasons for, and methods in dietary and food consumption surveys.", "content": "Reasons for, and methods in dietary and food consumption surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215416"} {"pmid": "4215417", "title": "Genetics of esterases in Drosophila. III. Influence of different chromosomes on esterase pattern in Drosophila.", "content": "Genetics of esterases in Drosophila. III. Influence of different chromosomes on esterase pattern in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215417"} {"pmid": "4215420", "title": "Maroteaux-Lamy disease (mucopolysaccharidosis VI), subtype A: deficiency of a N-acetylgalactosamine-4-sulfatase.", "content": "Maroteaux-Lamy disease (mucopolysaccharidosis VI), subtype A: deficiency of a N-acetylgalactosamine-4-sulfatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215420"} {"pmid": "4215419", "title": "Rabbit beta-glucuronidase. Subcellular distribution and immunochemical properties.", "content": "Rabbit beta-glucuronidase. Subcellular distribution and immunochemical properties. 1. The subcellular distribution of beta-glucuronidase and other hydrolases in rabbit liver was investigated. beta-Glucuronidase was found in both microsomal and lysosomal fractions. 2. Multiple forms of beta-glucuronidase were present in extracts of microsomal and lysosomal fractions. All forms were common to both fractions. 3. A specific antiserum against beta-glucuronidase was raised, and characterized by immunoprecipitation and affinity-chromatography procedures. 4. The immunological identity of the multiple forms in the pure beta-glucuronidase preparation, and the immunological identity of the beta-glucuronidase complement of lysosomal extracts with that of microsomal extracts, were demonstrated by means of the antiserum. The presence of inactive enzyme in various enzyme preparations was shown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215419"} {"pmid": "4215418", "title": "Rabbit beta-glucuronidase. Purification and properties, and the existence of multiple forms.", "content": "Rabbit beta-glucuronidase. Purification and properties, and the existence of multiple forms. 1. beta-Glucuronidase (EC 3.2.1.31) was purified from rabbit liver by a procedure involving autolysis, (NH(4))(2)SO(4) fractionation, chromatography on DEAE-cellulose and hydroxyapatite, gel filtration, sedimentation in a sucrose gradient, and isoelectric focusing. 2. Electron microscopy revealed ferritin as the major contaminant in later stages of purification and also showed aggregates of enzyme molecules. Particular attention was paid to the removal of ferritin. 3. The purified enzyme was homogeneous in polyacrylamide-gel electrophoresis both in non-dissociating conditions and in the presence of sodium dodecyl sulphate, and in Ouchterlony gel diffusion and immunoelectrophoresis against polyspecific antisera. 4. Sedimentation in sucrose gradients gave a molecular weight of 300000, whereas gel filtration indicated 440000. 5. Subunits of 75000 molecular weight were observed in gel electrophoresis in the presence of sodium dodecyl sulphate and in gel filtration in the presence of urea. 6. The K(m) value for p-nitrophenyl beta-d-glucuronide was 0.6mm, and the enzyme was extremely sensitive to lactone inhibitors. It was also inhibited by Hg(2+) ions. 7. Multiple forms were observed in the pure enzyme by isoelectric focusing, with pI values of 4.5-5.8. Subunits showed similar heterogeneity. The origin of the multiple forms was investigated in detail, and the possibility of artifact generation largely excluded. Some of the forms of lowest pI disappeared after neuraminidase digestion. The nature of the residual heterogeneity remains to be elucidated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215418"} {"pmid": "4215421", "title": "Change of enzyme activities during the early stage of influenza virus infection.", "content": "Change of enzyme activities during the early stage of influenza virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215421"} {"pmid": "4215411", "title": "Avian infectious bronchitis: demonstration of serum IgG- and IgM-neutralizing antibody by sucrose density-gradient centrifugation and mercaptoethanol reduction.", "content": "Avian infectious bronchitis: demonstration of serum IgG- and IgM-neutralizing antibody by sucrose density-gradient centrifugation and mercaptoethanol reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215411"} {"pmid": "4215412", "title": "Virucidal activity of commercial disinfectants against velogenic viscerotropic Newcastle disease virus.", "content": "Virucidal activity of commercial disinfectants against velogenic viscerotropic Newcastle disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215412"} {"pmid": "4215422", "title": "Chelation of divalent cations by lomofungin: role in inhibition of nucleic acid synthesis.", "content": "Chelation of divalent cations by lomofungin: role in inhibition of nucleic acid synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215422"} {"pmid": "4215423", "title": "Structure-activity relationships in the effects of 1-alkylimidazoles on microsomal oxidation in vitro and in vivo.", "content": "Structure-activity relationships in the effects of 1-alkylimidazoles on microsomal oxidation in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215423"} {"pmid": "4215424", "title": "Monoamine oxidase inhibitors and other drugs as inhibitors of diamine oxidase from human placenta and pig kidney.", "content": "Monoamine oxidase inhibitors and other drugs as inhibitors of diamine oxidase from human placenta and pig kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215424"} {"pmid": "4215430", "title": "7-nitro-8-acyloxyquinolines with antimicrobial and antifungal activity.", "content": "7-nitro-8-acyloxyquinolines with antimicrobial and antifungal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215430"} {"pmid": "4215425", "title": "Clinical features and serologic abnormalities in juvenile rheumatoid arthritis.", "content": "Clinical features and serologic abnormalities in juvenile rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215425"} {"pmid": "4215433", "title": "Antimicrobial studies in vitro with cephacetrile, a new cephalosporin derivative.", "content": "Antimicrobial studies in vitro with cephacetrile, a new cephalosporin derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215433"} {"pmid": "4215426", "title": "Letter: Serum gold determinations.", "content": "Letter: Serum gold determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215426"} {"pmid": "4215434", "title": "Pharmacokinetic studies in animals and humans of a new cephalosporin, the sodium salt of 7-cyanacetyl-amino-cephalosporanic acid.", "content": "Pharmacokinetic studies in animals and humans of a new cephalosporin, the sodium salt of 7-cyanacetyl-amino-cephalosporanic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215434"} {"pmid": "4215427", "title": "Letter: Long-term side effects of azathioprine.", "content": "Letter: Long-term side effects of azathioprine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215427"} {"pmid": "4215436", "title": "Experimental pseudomonas osteomyelitis: treatment with sisomicin and carbenicillin.", "content": "Experimental pseudomonas osteomyelitis: treatment with sisomicin and carbenicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215436"} {"pmid": "4215441", "title": "Proceedings: Postoperative measurement of blood flow in saphenous vein bypass grafts.", "content": "Proceedings: Postoperative measurement of blood flow in saphenous vein bypass grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215441"} {"pmid": "4215428", "title": "Qualitative characteristics of anti-DNA antibodies in lupus nephritis.", "content": "Qualitative characteristics of anti-DNA antibodies in lupus nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215428"} {"pmid": "4215429", "title": "Immunoglobulin E (IgE) levels in serum and synovial fluid in rheumatoid arthritis.", "content": "Immunoglobulin E (IgE) levels in serum and synovial fluid in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215429"} {"pmid": "4215442", "title": "Investigation of mechanisms of action of anti-tumour factors made from lymph nodes or spleens of allergized allogeneic mice.", "content": "Investigation of mechanisms of action of anti-tumour factors made from lymph nodes or spleens of allergized allogeneic mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215442"} {"pmid": "4215443", "title": "Intracellular killing of different strains of Pseudomonas aeruginosa by human leucocytes.", "content": "Intracellular killing of different strains of Pseudomonas aeruginosa by human leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215443"} {"pmid": "4215444", "title": "Vaccine potencies of the live vaccine strain of Francisella tularensis and isolated bacterial components.", "content": "Vaccine potencies of the live vaccine strain of Francisella tularensis and isolated bacterial components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215444"} {"pmid": "4215445", "title": "Hepatocellular uptake of ferritin in the rat.", "content": "Hepatocellular uptake of ferritin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215445"} {"pmid": "4215446", "title": "Plant carbonic anhydrase. Hydrase activity and its reversible inhibition.", "content": "Plant carbonic anhydrase. Hydrase activity and its reversible inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215446"} {"pmid": "4215447", "title": "Studies on interaction between poly(L-lysine 40, L-alanine 60) and deoxyribonucleic acids.", "content": "Studies on interaction between poly(L-lysine 40, L-alanine 60) and deoxyribonucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215447"} {"pmid": "4215448", "title": "Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid.", "content": "Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215448"} {"pmid": "4215449", "title": "The identification of poly-gamma-glutamyl chain lengths in bacterial folates.", "content": "The identification of poly-gamma-glutamyl chain lengths in bacterial folates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215449"} {"pmid": "4215450", "title": "Factors involved in the synthesis of cyclopropane fatty acids by Streptococcus faecalis.", "content": "Factors involved in the synthesis of cyclopropane fatty acids by Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215450"} {"pmid": "4215435", "title": "Effect of diet on hepatic and intestinal lipogenesis in squirrel, cebus, and cynomolgus monkeys.", "content": "Effect of diet on hepatic and intestinal lipogenesis in squirrel, cebus, and cynomolgus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215435"} {"pmid": "4215452", "title": "Physical properties and biological activities of two forms of alpha-N-acetylglucosaminidase from bovine spleen.", "content": "Physical properties and biological activities of two forms of alpha-N-acetylglucosaminidase from bovine spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215452"} {"pmid": "4215451", "title": "Physiological differences between cyclopropane fatty acid-deficient mutants and the parent strain of Streptococcus faecalis.", "content": "Physiological differences between cyclopropane fatty acid-deficient mutants and the parent strain of Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215451"} {"pmid": "4215453", "title": "Further characterization of human thyroxine-binding globulin.", "content": "Further characterization of human thyroxine-binding globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215453"} {"pmid": "4215454", "title": "Legume root nodule nitrogenase. Purification, properties, and studies on its genetic control.", "content": "Legume root nodule nitrogenase. Purification, properties, and studies on its genetic control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215454"} {"pmid": "4215455", "title": "Activation of platelet fibrin-stabilizing factor by thrombin.", "content": "Activation of platelet fibrin-stabilizing factor by thrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215455"} {"pmid": "4215456", "title": "Amino acid sequence of sheep carbonic anhydrase C.", "content": "Amino acid sequence of sheep carbonic anhydrase C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215456"} {"pmid": "4215457", "title": "SomeSome characteristics of a phospholipase A2 from sheep red cell membranes.", "content": "SomeSome characteristics of a phospholipase A2 from sheep red cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215457"} {"pmid": "4215458", "title": "Lecithinase activities at the external surface of ruminant erythrocyte membranes.", "content": "Lecithinase activities at the external surface of ruminant erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215458"} {"pmid": "4215459", "title": "Genetic complexity of mitochondrial DNA from Euglena gracilis.", "content": "Genetic complexity of mitochondrial DNA from Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215459"} {"pmid": "4215460", "title": "Properties of mitochondrial DNA from Kluyveromyces lactis.", "content": "Properties of mitochondrial DNA from Kluyveromyces lactis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215460"} {"pmid": "4215461", "title": "The attachment of polyribosomes to membranes of the hypocotyl of Phaseolus vulgaris.", "content": "The attachment of polyribosomes to membranes of the hypocotyl of Phaseolus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215461"} {"pmid": "4215462", "title": "Solubilization and properties of poly(ADP-ribose) polymerases from bovine spleen and Ehrlich ascites cells.", "content": "Solubilization and properties of poly(ADP-ribose) polymerases from bovine spleen and Ehrlich ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215462"} {"pmid": "4215463", "title": "Size and configuration of mitochondrial DNA in Euglena gracilis.", "content": "Size and configuration of mitochondrial DNA in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215463"} {"pmid": "4215464", "title": "Subunit structure of DNA-dependent RNA polymerase of Anacystis nidulans.", "content": "Subunit structure of DNA-dependent RNA polymerase of Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215464"} {"pmid": "4215469", "title": "Loss of cellular material from suspensions of isolated epithelial cells of guinea pig small intestine.", "content": "Loss of cellular material from suspensions of isolated epithelial cells of guinea pig small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215469"} {"pmid": "4215471", "title": "Anti-h absorbed by, and eluted from Oh (Bombay) red blood cells.", "content": "Anti-h absorbed by, and eluted from Oh (Bombay) red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215471"} {"pmid": "4215473", "title": "Two proposed general configurations for bacterial cell wall peptidoglycans shown by space-filling molecular models.", "content": "Two proposed general configurations for bacterial cell wall peptidoglycans shown by space-filling molecular models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215473"} {"pmid": "4215472", "title": "Effect of metal binding on the intrinsic fluorescence of bovine carbonic anhydrase.", "content": "Effect of metal binding on the intrinsic fluorescence of bovine carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215472"} {"pmid": "4215474", "title": "Qualitative and quantitative mass spectrometry of some noncatecholic biogenic amines and related compounds as their dansyl derivatives.", "content": "Qualitative and quantitative mass spectrometry of some noncatecholic biogenic amines and related compounds as their dansyl derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215474"} {"pmid": "4215475", "title": "Treatment related observations in solid tissues, fibroblast cultured and amniotic fluid cells of type II glycogenosis, Hurler disease and metachromatic leukodystrophy.", "content": "Treatment related observations in solid tissues, fibroblast cultured and amniotic fluid cells of type II glycogenosis, Hurler disease and metachromatic leukodystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215475"} {"pmid": "4215476", "title": "Enzyme replacement in genetic disease. Prospectus.", "content": "Enzyme replacement in genetic disease. Prospectus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215476"} {"pmid": "4215477", "title": "Mucopolysaccharide-storage diseases: corrective activity of normal human serum and lymphocyte extracts.", "content": "Mucopolysaccharide-storage diseases: corrective activity of normal human serum and lymphocyte extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215477"} {"pmid": "4215478", "title": "Fabry disease: kidney transplantation as an enzyme replacement technic.", "content": "Fabry disease: kidney transplantation as an enzyme replacement technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215478"} {"pmid": "4215479", "title": "Fabry disease: correction of the enzymatic deficiency by renal transplantation.", "content": "Fabry disease: correction of the enzymatic deficiency by renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215479"} {"pmid": "4215480", "title": "Enzyme replacement in Fabry disease: treatment of cultured skin fibroblasts with a purified alpha-galactosidase from ficin.", "content": "Enzyme replacement in Fabry disease: treatment of cultured skin fibroblasts with a purified alpha-galactosidase from ficin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215480"} {"pmid": "4215485", "title": "Distribution of polychlorinated biphenyls in an aerated biological oxidation wastewater treatment system.", "content": "Distribution of polychlorinated biphenyls in an aerated biological oxidation wastewater treatment system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215485"} {"pmid": "4215486", "title": "Polychlorinated biopenyls. V. Synthesis of 14C-labelled 2,2', 4,4',5,5'-hexachlorobiphenyl, a major component in PCB-mixtures.", "content": "Polychlorinated biopenyls. V. Synthesis of 14C-labelled 2,2', 4,4',5,5'-hexachlorobiphenyl, a major component in PCB-mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215486"} {"pmid": "4215487", "title": "Effects of dieldrin and PCB's upon the production and morphology of Japanese quail eggs.", "content": "Effects of dieldrin and PCB's upon the production and morphology of Japanese quail eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215487"} {"pmid": "4215489", "title": "Analyses of polychlorinated biphenyls in bird tissues and Aroclor standards with gas chromatography and mass spectrometry.", "content": "Analyses of polychlorinated biphenyls in bird tissues and Aroclor standards with gas chromatography and mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215489"} {"pmid": "4215488", "title": "Recovery of trichlorfon (Dylox) and carbaryl (Sevin) in songbirds following spraying of forest for gypsy moth.", "content": "Recovery of trichlorfon (Dylox) and carbaryl (Sevin) in songbirds following spraying of forest for gypsy moth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215488"} {"pmid": "4215490", "title": "Interference in the electron-capture technique for determination of polychlorinated biphenyls by sulfur-containing compounds in petroleum products.", "content": "Interference in the electron-capture technique for determination of polychlorinated biphenyls by sulfur-containing compounds in petroleum products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215490"} {"pmid": "4215491", "title": "DDT, DDE and PCBs in the tissues of reef dwelling groupers (Serranidae) in the Gulf of Mexico and the Grand Bahamas.", "content": "DDT, DDE and PCBs in the tissues of reef dwelling groupers (Serranidae) in the Gulf of Mexico and the Grand Bahamas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215491"} {"pmid": "4215492", "title": "PCB'S and p,p' DDE in the blood of cachectic patients.", "content": "PCB'S and p,p' DDE in the blood of cachectic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215492"} {"pmid": "4215494", "title": "Comparison of polychlorinated biphenyls in yusho patients and ordinary persons.", "content": "Comparison of polychlorinated biphenyls in yusho patients and ordinary persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215494"} {"pmid": "4215493", "title": "Time-course of induction of microsomal enzymes following treatment with polychlorinated biphenyl.", "content": "Time-course of induction of microsomal enzymes following treatment with polychlorinated biphenyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215493"} {"pmid": "4215495", "title": "Dissipation of Guthion Sevin, Polyram, Phygon and Systox from apple orchard soil.", "content": "Dissipation of Guthion Sevin, Polyram, Phygon and Systox from apple orchard soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215495"} {"pmid": "4215496", "title": "Bacterial degradation of polychlorinated biphenyls. I. Identification of some metabolic products from Aroclor 1242.", "content": "Bacterial degradation of polychlorinated biphenyls. I. Identification of some metabolic products from Aroclor 1242.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215496"} {"pmid": "4215497", "title": "Accumulation of Aroclor 1254 in grass shrimp (Palaemonetes pugio) in laboratory and field exposures.", "content": "Accumulation of Aroclor 1254 in grass shrimp (Palaemonetes pugio) in laboratory and field exposures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215497"} {"pmid": "4215498", "title": "Gas chromatography and mass spectrometry of polychlorinated terphenyls (Aroclor 5460).", "content": "Gas chromatography and mass spectrometry of polychlorinated terphenyls (Aroclor 5460).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215498"} {"pmid": "4215499", "title": "Effect of aflatoxin B1, ochratoxin and rubratoxin B on a protozoan, Tetrahymena pyriformis HSM.", "content": "Effect of aflatoxin B1, ochratoxin and rubratoxin B on a protozoan, Tetrahymena pyriformis HSM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215499"} {"pmid": "4215500", "title": "DDE, PCB and aldrin levels in Arctic birds of Greenland.", "content": "DDE, PCB and aldrin levels in Arctic birds of Greenland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215500"} {"pmid": "4215502", "title": "Polychlorinated biphenyls and p,p' DDE in green turtle eggs from Ascension Island, South Atlantic Ocean.", "content": "Polychlorinated biphenyls and p,p' DDE in green turtle eggs from Ascension Island, South Atlantic Ocean.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215502"} {"pmid": "4215501", "title": "A gas chromatographic-mass spectrometric comparison of polychlorinated biphenyl residues in the Japanese quail brain to an Aroclor standard.", "content": "A gas chromatographic-mass spectrometric comparison of polychlorinated biphenyl residues in the Japanese quail brain to an Aroclor standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215501"} {"pmid": "4215503", "title": "High-volume collection of atmospheric polychlorinated biphenyls.", "content": "High-volume collection of atmospheric polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215503"} {"pmid": "4215504", "title": "Embryotoxic and teratogenic effects in unhatched fertile eggs from hens fed polychlorinated biphenyls (PCBs).", "content": "Embryotoxic and teratogenic effects in unhatched fertile eggs from hens fed polychlorinated biphenyls (PCBs).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215504"} {"pmid": "4215505", "title": "Effects of nonpersistent pesticides on liver weight, lipids and vitamin A of rats and quail.", "content": "Effects of nonpersistent pesticides on liver weight, lipids and vitamin A of rats and quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215505"} {"pmid": "4215506", "title": "Chlorinated insecticide residues in the eggs of some freshwater fish.", "content": "Chlorinated insecticide residues in the eggs of some freshwater fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215506"} {"pmid": "4215507", "title": "Uptake of a PCB (Aroclor 1254) from soil by carrots under field conditions.", "content": "Uptake of a PCB (Aroclor 1254) from soil by carrots under field conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215507"} {"pmid": "4215508", "title": "Effect of diethylstilbestrol on feedlot associated bacteria.", "content": "Effect of diethylstilbestrol on feedlot associated bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215508"} {"pmid": "4215510", "title": "Gas-liquid chromatography--mass spectrometric characterization of aroclor 1242 and 1254 components.", "content": "Gas-liquid chromatography--mass spectrometric characterization of aroclor 1242 and 1254 components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215510"} {"pmid": "4215509", "title": "Translocation of four organochlorine compounds by red mangrove (Rhizophora mangle L.) seedlings.", "content": "Translocation of four organochlorine compounds by red mangrove (Rhizophora mangle L.) seedlings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215509"} {"pmid": "4215511", "title": "The effect of age and sex on the toxicity of Aroclor 1254, a polychlorinated biphenyl, in the rat.", "content": "The effect of age and sex on the toxicity of Aroclor 1254, a polychlorinated biphenyl, in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215511"} {"pmid": "4215512", "title": "Mercury and selected pesticide levels in fish and wildlife of Utah: II. Levels of mercury, DDT, DDE, dieldrin and PCB in chukars, pheasants and waterfowl.", "content": "Mercury and selected pesticide levels in fish and wildlife of Utah: II. Levels of mercury, DDT, DDE, dieldrin and PCB in chukars, pheasants and waterfowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215512"} {"pmid": "4215513", "title": "Acute effects of Aroclor 1254 (PCB) on Ictalurus punctatus (catfish).", "content": "Acute effects of Aroclor 1254 (PCB) on Ictalurus punctatus (catfish).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215513"} {"pmid": "4215515", "title": "Avoidance of Aroclor 1254 by shrimp and fishes.", "content": "Avoidance of Aroclor 1254 by shrimp and fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215515"} {"pmid": "4215514", "title": "Mercury and selected pesticide levels in fish and wildlife of Utah: I. Levels of mercury, DDT, DDE, dieldrin and PCB in fish.", "content": "Mercury and selected pesticide levels in fish and wildlife of Utah: I. Levels of mercury, DDT, DDE, dieldrin and PCB in fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215514"} {"pmid": "4215516", "title": "Presence of PCB, DDE and DDT in human milk in the provinces of New Brunswick and NOVA Scotia, Canada.", "content": "Presence of PCB, DDE and DDT in human milk in the provinces of New Brunswick and NOVA Scotia, Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215516"} {"pmid": "4215517", "title": "Efficacy of home laundering in removal of DDT, methyl parathion and toxaphene residues from contaminated fabrics.", "content": "Efficacy of home laundering in removal of DDT, methyl parathion and toxaphene residues from contaminated fabrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215517"} {"pmid": "4215519", "title": "The finding of chlorinated dibenzofurans in a Japanese polychlorinated biphenyl sample.", "content": "The finding of chlorinated dibenzofurans in a Japanese polychlorinated biphenyl sample.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215519"} {"pmid": "4215518", "title": "Some aspects of the recovery of chlorinated residues (DDT-type compounds and PCB) from fish tissue by using different extraction methods.", "content": "Some aspects of the recovery of chlorinated residues (DDT-type compounds and PCB) from fish tissue by using different extraction methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215518"} {"pmid": "4215520", "title": "Effect of PCB ingestion on sleeping times, organ weights, food consumption, serum corticosterone and survival of albino mice.", "content": "Effect of PCB ingestion on sleeping times, organ weights, food consumption, serum corticosterone and survival of albino mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215520"} {"pmid": "4215521", "title": "Uptake of chlorinated paraffins and PCB from suspended solids and food by juvenile Atlantic salmon.", "content": "Uptake of chlorinated paraffins and PCB from suspended solids and food by juvenile Atlantic salmon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215521"} {"pmid": "4215522", "title": "Polychlorinated biphenyl emission from fluorescent lamp ballasts.", "content": "Polychlorinated biphenyl emission from fluorescent lamp ballasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215522"} {"pmid": "4215523", "title": "Reduction of pentobarbital-induced sleeping times in PCB-treated cottontail rabbits.", "content": "Reduction of pentobarbital-induced sleeping times in PCB-treated cottontail rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215523"} {"pmid": "4215524", "title": "Metabolism of 2,2'-dichlorobiphenyl-14C in two plant-water-soil-systems.", "content": "Metabolism of 2,2'-dichlorobiphenyl-14C in two plant-water-soil-systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215524"} {"pmid": "4215525", "title": "Residues of organochlorine insecticides and PCBs in samples of Norwegian butter 1966-1972.", "content": "Residues of organochlorine insecticides and PCBs in samples of Norwegian butter 1966-1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215525"} {"pmid": "4215526", "title": "The use of polyurethane foam plugs for extraction of polychlorinated biphenyls (PCB's) from natural waters.", "content": "The use of polyurethane foam plugs for extraction of polychlorinated biphenyls (PCB's) from natural waters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215526"} {"pmid": "4215527", "title": "The teeth of hominids, hominoids and pongids.", "content": "The teeth of hominids, hominoids and pongids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215527"} {"pmid": "4215528", "title": "Jacksonian seizure arising from the contralateral hippocampus.", "content": "Jacksonian seizure arising from the contralateral hippocampus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215528"} {"pmid": "4215529", "title": "The relative effectiveness of super- and orthovoltage x rays for intestinal damage in man and mouse: an apparent discrepancy and its explanation.", "content": "The relative effectiveness of super- and orthovoltage x rays for intestinal damage in man and mouse: an apparent discrepancy and its explanation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215529"} {"pmid": "4215530", "title": "Relative biological effectiveness (RBE) of 30 MeV electrons at varying depths in tissue.", "content": "Relative biological effectiveness (RBE) of 30 MeV electrons at varying depths in tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215530"} {"pmid": "4215531", "title": "Letter: SI Units in radiology.", "content": "Letter: SI Units in radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215531"} {"pmid": "4215532", "title": "Comparative radiobiological measurements with two high-energy cyclotron-produced neutron beams presently used for radiotherapy.", "content": "Comparative radiobiological measurements with two high-energy cyclotron-produced neutron beams presently used for radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215532"} {"pmid": "4215533", "title": "Letter: Recent advances in the development of a 14 MeV neutron generator suitable for radiotherapy.", "content": "Letter: Recent advances in the development of a 14 MeV neutron generator suitable for radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215533"} {"pmid": "4215534", "title": "Total body potassium in long-term frusemide therapy: is potassium supplementation necessary?", "content": "Total body potassium in long-term frusemide therapy: is potassium supplementation necessary? Measurements of total body potassium (T.B.K.) were made by whole-body counting in four groups of patients receiving oral frusemide for one year. Patients in group 1 had essential hypertension and normal renal function and received 40 mg frusemide daily without potassium supplements. Patients in group 2 were similar but received oral potassium supplements for the first four months of treatment. Patients in group 3 had hypertension associated with renal disease and received 120 mg frusemide daily without potassium supplements. Patients in group 4 also had hypertension and renal impairment and in addition to 120 mg frusemide daily they received oral potassium supplements for four months. No evidence of depletion of T.B.K. was found in any of the groups after continuous treatment with frusemide for one year. It is questioned whether potassium supplementation in long term diuretic therapy with frusemide is necessary unless there is evidence of pre-existing potassium depletion or of some other factor such as cardiac failure, cirrhosis of the liver, or the nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215534"} {"pmid": "4215535", "title": "Letter: Two-phase blood culture system.", "content": "Letter: Two-phase blood culture system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215535"} {"pmid": "4215537", "title": "Letter: Gianotti-Crosti syndrome and viral infection.", "content": "Letter: Gianotti-Crosti syndrome and viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215537"} {"pmid": "4215536", "title": "Absorption of slow-release iron and effects of ascorbic acid in normal subjects and after partial gastrectomy.", "content": "Absorption of slow-release iron and effects of ascorbic acid in normal subjects and after partial gastrectomy. Radiolabelled tablets of slow-release iron and ferrous sulphate containing 50 mg of elemental iron were given to 28 patients, and iron absorption was studied using a whole body counter.There was no significant difference between the absorption of ferrous sulphate and that of slow-release iron in normal subjects, anaemic patients, anaemic and non-anaemic post-gastrectomy patients, or those with coeliac disease. Ascorbic acid potentiated iron absorption, especially in anaemic post-gastrectomy patients.The indications and hazards of slow release iron preparations are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215536"} {"pmid": "4215538", "title": "Editorial: Medical nemesis.", "content": "Editorial: Medical nemesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215538"} {"pmid": "4215539", "title": "Medical Nemesis--three views. \"Medicalization\" of health.", "content": "Medical Nemesis--three views. \"Medicalization\" of health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215539"} {"pmid": "4215540", "title": "Medical nemesis--three views. Indictment of medical care.", "content": "Medical nemesis--three views. Indictment of medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215540"} {"pmid": "4215541", "title": "Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries.", "content": "Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215541"} {"pmid": "4215542", "title": "A crescent-shaped cortical visual area surrounding the middle temporal area (MT) in the owl monkey (Aotus trivirgatus).", "content": "A crescent-shaped cortical visual area surrounding the middle temporal area (MT) in the owl monkey (Aotus trivirgatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215542"} {"pmid": "4215543", "title": "Choline acetyltransferase localization in the central nervous system by immunohistochemistry.", "content": "Choline acetyltransferase localization in the central nervous system by immunohistochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215543"} {"pmid": "4215545", "title": "On the elicitability of vocalization from the cortical larynx area.", "content": "On the elicitability of vocalization from the cortical larynx area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215545"} {"pmid": "4215544", "title": "Catecholamine-binding protein in mouse brain: isolation and characterization.", "content": "Catecholamine-binding protein in mouse brain: isolation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215544"} {"pmid": "4215549", "title": "Directed mutation in Streptomyces lipmanii.", "content": "Directed mutation in Streptomyces lipmanii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215549"} {"pmid": "4215551", "title": "Action of streptomycin on the growth of Streptomyces griseus.", "content": "Action of streptomycin on the growth of Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215551"} {"pmid": "4215550", "title": "Purification of Rickettsia rickettsi by density-gradient zonal centrifugation.", "content": "Purification of Rickettsia rickettsi by density-gradient zonal centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215550"} {"pmid": "4215553", "title": "Minicell formation in chloramphenicol-treated Bacillus cereus.", "content": "Minicell formation in chloramphenicol-treated Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215553"} {"pmid": "4215552", "title": "Growth abnormalities in microorganisms exposed to tobacco leaf extracts.", "content": "Growth abnormalities in microorganisms exposed to tobacco leaf extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215552"} {"pmid": "4215554", "title": "Localization of neuroendocrine functions within the hypothalamus.", "content": "Localization of neuroendocrine functions within the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215554"} {"pmid": "4215556", "title": "Myasthenia gravis associated with diphenylhydantoin therapy for epilepsy.", "content": "Myasthenia gravis associated with diphenylhydantoin therapy for epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215556"} {"pmid": "4215557", "title": "Letter: Rh sensitization following abortion.", "content": "Letter: Rh sensitization following abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215557"} {"pmid": "4215555", "title": "Role of the ventricular system in neuroendocrine processes: synthesis and distribution of thyrotropin releasing factor (TRF) in the hypothalamus and third ventricle.", "content": "Role of the ventricular system in neuroendocrine processes: synthesis and distribution of thyrotropin releasing factor (TRF) in the hypothalamus and third ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215555"} {"pmid": "4215558", "title": "The effect of dexamethasone on TSH and prolactin secretion after TRH stimulation.", "content": "The effect of dexamethasone on TSH and prolactin secretion after TRH stimulation. Serum thyrotropin (TSH) and prolactin levels were measured after intravenous administration of 400 mug of synthetic thyrotropin-releasing hormone (TRH) in 13 normal subjects and six hypothyroid patients before and after three days of administration of dexamethasone 2 mg per day. In the normal subjects dexamethasone suppressed baseline serum levels and secretion of TSH after TRH stimulation. On the other hand, it had no effect on the hypothyroid patients. In the control group dexamethasone also suppressed baseline serum levels but not secretion of prolactin after TRH stimulation. Dexamethasone had no effect on prolactin levels in the hypothyroid group. It is concluded that in normal patients short-term administration of dexamethasone has an inhibitory effect on TSH secretion at the pituitary level. As for prolactin, our results could indicate that TRH is a more potent stimulator of prolactin secretion than of TSH secretion, or that TSH and prolactin pituitary thresholds for TRH are different.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215558"} {"pmid": "4215559", "title": "Comparison of amoxicillin and ampicillin in single-dose oral treatment of males with gonococcal urethritis.", "content": "Comparison of amoxicillin and ampicillin in single-dose oral treatment of males with gonococcal urethritis. Amoxicillin in single oral doses of 2.0 g, 2.0 g plus 1.0 g probenecid, or 3.0 g was compared with ampicillin 3.5 g plus 1.0 g probenecid in the treatment of 203 males with uncomplicated acute gonococcal urethritis. Cure rates above 95% were produced by all treatments except the 2.0-g amoxicillin dose, which cured 89% of patients. Of 198 pretreatment gonococcus isolates tested by an agar dilution technique for susceptibility to penicillin G, ampicillin and amoxicillin, over 50% showed relative resistance (MIC > 0.06 mug/ml) to the antibiotics. However, amoxicillin was somewhat more active against isolates showing considerable resistance (MIC >/= 1.0 mug/ml) to penicillin G or ampicillin. Adverse effects of amoxicillin were few: two patients reported transient nausea and six noted short-lived diarrhea. No hypersensitivity reactions were observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215559"} {"pmid": "4215561", "title": "Radiotherapy for carcinoma of the cervix recurrent after surgery.", "content": "Radiotherapy for carcinoma of the cervix recurrent after surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215561"} {"pmid": "4215562", "title": "Coronary collateral flow following acute coronary occlusion: a diastolic phenomenon.", "content": "Coronary collateral flow following acute coronary occlusion: a diastolic phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215562"} {"pmid": "4215560", "title": "Nursing needs of ambulatory patients with chronic disease.", "content": "Nursing needs of ambulatory patients with chronic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215560"} {"pmid": "4215572", "title": "Structure-activity dependence in some novel ring-substituted 3,3-dimethyl-1-phenyltriazenes. Genetic effects in Drosophila melanogaster and in Saccharomyces cerevisiae by a direct and a host-mediated assay.", "content": "Structure-activity dependence in some novel ring-substituted 3,3-dimethyl-1-phenyltriazenes. Genetic effects in Drosophila melanogaster and in Saccharomyces cerevisiae by a direct and a host-mediated assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215572"} {"pmid": "4215571", "title": "Comparative effects of commercial Aroclors on rat liver enzyme activities.", "content": "Comparative effects of commercial Aroclors on rat liver enzyme activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215571"} {"pmid": "4215573", "title": "The synthesis of a DOPA analogue, 1-amino-2-(3, 4-dihydroxyphenyl)-ethylphosphonic acid and distribution studies in mice bearing the Harding-Passey melanoma.", "content": "The synthesis of a DOPA analogue, 1-amino-2-(3, 4-dihydroxyphenyl)-ethylphosphonic acid and distribution studies in mice bearing the Harding-Passey melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215573"} {"pmid": "4215574", "title": "The effect of aflatoxin B, on the maturation of ribosomal and transfer RNA in monkey kidney (CV-1) cells in culture.", "content": "The effect of aflatoxin B, on the maturation of ribosomal and transfer RNA in monkey kidney (CV-1) cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215574"} {"pmid": "4215597", "title": "Eye abnormalities and skeletal deformities in the Pierre Robin syndrome: a balanced evaluation.", "content": "Eye abnormalities and skeletal deformities in the Pierre Robin syndrome: a balanced evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215597"} {"pmid": "4215598", "title": "Changes of individual proteins in mother and newborn.", "content": "Changes of individual proteins in mother and newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215598"} {"pmid": "4215601", "title": "Study of bile proteins in difuse chronic hepatopathies.", "content": "Study of bile proteins in difuse chronic hepatopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215601"} {"pmid": "4215602", "title": "Electrophoretic forms of human liver alpha-L-fucosidase and their relationship to fucosidosis (mucopolysaccharidosis F).", "content": "Electrophoretic forms of human liver alpha-L-fucosidase and their relationship to fucosidosis (mucopolysaccharidosis F).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215602"} {"pmid": "4215603", "title": "The molecular nature of alpha-fetoprotein in anencephaly and spina bifida.", "content": "The molecular nature of alpha-fetoprotein in anencephaly and spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215603"} {"pmid": "4215604", "title": "Biosynthesis of parathyroid hormone.", "content": "Biosynthesis of parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215604"} {"pmid": "4215606", "title": "Lack of suppression of certain immunoglobulin-producing lymphocytes in T-lymphocyte deficiency.", "content": "Lack of suppression of certain immunoglobulin-producing lymphocytes in T-lymphocyte deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215606"} {"pmid": "4215605", "title": "Precipitating anti-adrenal antibodies in Addison's disease.", "content": "Precipitating anti-adrenal antibodies in Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215605"} {"pmid": "4215608", "title": "Proceedings: Dietary folates and their availability to man.", "content": "Proceedings: Dietary folates and their availability to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215608"} {"pmid": "4215607", "title": "Micrognathia and glossoptosis in the newborn. Surgical tacking of the tongue in small jaw syndromes.", "content": "Micrognathia and glossoptosis in the newborn. Surgical tacking of the tongue in small jaw syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215607"} {"pmid": "4215609", "title": "Proceedings: The intracellular pH and potassium content of rabbit cardiac and skeletal muscle in potassium depletion.", "content": "Proceedings: The intracellular pH and potassium content of rabbit cardiac and skeletal muscle in potassium depletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215609"} {"pmid": "4215612", "title": "Characterization of a ribonuclease from the hepatopancreas of the queen scallop, Chlamys opercularis.", "content": "Characterization of a ribonuclease from the hepatopancreas of the queen scallop, Chlamys opercularis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215612"} {"pmid": "4215614", "title": "The J chain of polymeric immunoglobulins.", "content": "The J chain of polymeric immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215614"} {"pmid": "4215613", "title": "Some biochemical characteristics of the salivary gland products of Macaca irus and Cercopithecus aethiops.", "content": "Some biochemical characteristics of the salivary gland products of Macaca irus and Cercopithecus aethiops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215613"} {"pmid": "4215615", "title": "Phylogenetic aspects of immunoglobulin variable region diversity.", "content": "Phylogenetic aspects of immunoglobulin variable region diversity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215615"} {"pmid": "4215616", "title": "mRNA for H and L chains of immunoglobulin: specific control of H-chain production.", "content": "mRNA for H and L chains of immunoglobulin: specific control of H-chain production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215616"} {"pmid": "4215618", "title": "Pyrbuterol: a new bronchodilator. Phase I-single dose study.", "content": "Pyrbuterol: a new bronchodilator. Phase I-single dose study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215618"} {"pmid": "4215617", "title": "Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.", "content": "Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215617"} {"pmid": "4215619", "title": "A system for the clinical assessment of the antitussive activity of caramiphen.", "content": "A system for the clinical assessment of the antitussive activity of caramiphen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215619"} {"pmid": "4215621", "title": "Local and systemic effects of beclomethasone inhalation in steroid-dependent asthmatic patients.", "content": "Local and systemic effects of beclomethasone inhalation in steroid-dependent asthmatic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215621"} {"pmid": "4215620", "title": "Hemodynamic effects of ethaverine hydrochloride in patients with peripheral vascular disease.", "content": "Hemodynamic effects of ethaverine hydrochloride in patients with peripheral vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215620"} {"pmid": "4215622", "title": "Arterial hypertension northwest Florida public health survey-I. Methodology.", "content": "Arterial hypertension northwest Florida public health survey-I. Methodology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215622"} {"pmid": "4215623", "title": "Comparative bioavailability of doxycycline.", "content": "Comparative bioavailability of doxycycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215623"} {"pmid": "4215624", "title": "Hirschsprung's disease: its aetiology, pathogenesis and differential diagnosis.", "content": "Hirschsprung's disease: its aetiology, pathogenesis and differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215624"} {"pmid": "4215632", "title": "[Normal body temperature and influencing factors].", "content": "[Normal body temperature and influencing factors].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215632"} {"pmid": "4215641", "title": "Serum and liver lipids in normal baboons: effect of different carbohydrate diets.", "content": "Serum and liver lipids in normal baboons: effect of different carbohydrate diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215641"} {"pmid": "4215640", "title": "Prostaglandins: current therapeutic status in obstetrics.", "content": "Prostaglandins: current therapeutic status in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215640"} {"pmid": "4215643", "title": "The effect of a single large dose of thyrotropin-releasing hormone on various aspects of thyroid function in the rat.", "content": "The effect of a single large dose of thyrotropin-releasing hormone on various aspects of thyroid function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215643"} {"pmid": "4215644", "title": "Proceedings: Treatment of chronic proctitis with disodium cromoglycate.", "content": "Proceedings: Treatment of chronic proctitis with disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215644"} {"pmid": "4215645", "title": "Proceedings: The influence of ethacrynic acid and aspirin on water and electrolyte secretion induced by prostaglandin E1 in the human jejunum.", "content": "Proceedings: The influence of ethacrynic acid and aspirin on water and electrolyte secretion induced by prostaglandin E1 in the human jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215645"} {"pmid": "4215646", "title": "Proceedings: Serum complement components C3 and C4 in inflammatory bowel disease.", "content": "Proceedings: Serum complement components C3 and C4 in inflammatory bowel disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215646"} {"pmid": "4215647", "title": "Gel filtration of thyroxine - binding proteins of human serum.", "content": "Gel filtration of thyroxine - binding proteins of human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215647"} {"pmid": "4215648", "title": "Thyroxine content in the thyroid gland of domestic animals. Part VII. Iodinated tyrosines and thyronines in the serum of she camel at various reproductive stages.", "content": "Thyroxine content in the thyroid gland of domestic animals. Part VII. Iodinated tyrosines and thyronines in the serum of she camel at various reproductive stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215648"} {"pmid": "4215649", "title": "The structure and metabolism of starch.", "content": "The structure and metabolism of starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215649"} {"pmid": "4215650", "title": "Evidence in favour of the modification in vivo of RNA polymerase subunits during sporogenesis in Bacillus thuringiensis.", "content": "Evidence in favour of the modification in vivo of RNA polymerase subunits during sporogenesis in Bacillus thuringiensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215650"} {"pmid": "4215651", "title": "Active transport of maltose in Escherichia coli K12. Involvement of a \"periplasmic\" maltose binding protein.", "content": "Active transport of maltose in Escherichia coli K12. Involvement of a \"periplasmic\" maltose binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215651"} {"pmid": "4215652", "title": "A suppressor of nonsense mutations in Bacillus subtilis.", "content": "A suppressor of nonsense mutations in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215652"} {"pmid": "4215653", "title": "Correlation between the level of vitamin-B12-dependent methionine synthetase and intracellular concentration of vitamin B12 in some bacteria.", "content": "Correlation between the level of vitamin-B12-dependent methionine synthetase and intracellular concentration of vitamin B12 in some bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215653"} {"pmid": "4215654", "title": "Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase.", "content": "Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215654"} {"pmid": "4215656", "title": "Purification and properties of alpha-D-mannosidase from Medicago sativa L.", "content": "Purification and properties of alpha-D-mannosidase from Medicago sativa L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215656"} {"pmid": "4215655", "title": "Protein A from Staphylococcus aureus. The effect of iodination on the reactivity with immunoglobulin G.", "content": "Protein A from Staphylococcus aureus. The effect of iodination on the reactivity with immunoglobulin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215655"} {"pmid": "4215657", "title": "Inhibition by chloramphenicol of aminoazo dye carcinogenesis in rat liver: RNA synthesis in isolated liver nuclei.", "content": "Inhibition by chloramphenicol of aminoazo dye carcinogenesis in rat liver: RNA synthesis in isolated liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215657"} {"pmid": "4215658", "title": "The relative biological effectiveness of cyclotron fast neutrons for early and late damage to the small intestine of the mouse.", "content": "The relative biological effectiveness of cyclotron fast neutrons for early and late damage to the small intestine of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215658"} {"pmid": "4215659", "title": "Histamine catabolism in guinea pigs, rats and mice.", "content": "Histamine catabolism in guinea pigs, rats and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215659"} {"pmid": "4215660", "title": "Differences in papaverine inhibition of prostaglandin-induced contraction of aortic strips from normal and spontaneously hypertensive rats (SHR).", "content": "Differences in papaverine inhibition of prostaglandin-induced contraction of aortic strips from normal and spontaneously hypertensive rats (SHR).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215660"} {"pmid": "4215665", "title": "Change in cell-to-dish contact of cultured mammalian cells induced by concanavalin A.", "content": "Change in cell-to-dish contact of cultured mammalian cells induced by concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215665"} {"pmid": "4215666", "title": "Evidence for long-range electrostatic repulsion between HeLa cells.", "content": "Evidence for long-range electrostatic repulsion between HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215666"} {"pmid": "4215667", "title": "Vitamin B12 and the macromolecular composition of Euglena. I. Kinetic analysis of the cell cycle and chloroplast replication.", "content": "Vitamin B12 and the macromolecular composition of Euglena. I. Kinetic analysis of the cell cycle and chloroplast replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215667"} {"pmid": "4215668", "title": "Effect of bilateral intracerebral ablation on the gastric secretory response to insulin-induced hypoglycemia.", "content": "Effect of bilateral intracerebral ablation on the gastric secretory response to insulin-induced hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215668"} {"pmid": "4215669", "title": "Retention of noradrenaline-3H in brain and preferential extraction of labeled metabolites by glutaraldehyde fixation.", "content": "Retention of noradrenaline-3H in brain and preferential extraction of labeled metabolites by glutaraldehyde fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215669"} {"pmid": "4215670", "title": "Tremorogenic effect of thyrotropin releasing hormone in rats.", "content": "Tremorogenic effect of thyrotropin releasing hormone in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215670"} {"pmid": "4215661", "title": "Determination of the LD01 and extrapolation of the LD001 for five methylcarbamate pesticides.", "content": "Determination of the LD01 and extrapolation of the LD001 for five methylcarbamate pesticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215661"} {"pmid": "4215671", "title": "Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone: evidence by fluorescence histochemistry.", "content": "Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone: evidence by fluorescence histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215671"} {"pmid": "4215672", "title": "Reproductive incompatibility between similar genotype flies (Drosophila melanogaster) raised at two different temperatures.", "content": "Reproductive incompatibility between similar genotype flies (Drosophila melanogaster) raised at two different temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215672"} {"pmid": "4215673", "title": "Effect of sulpiride on prolactin release by rat pituitaries in vitro.", "content": "Effect of sulpiride on prolactin release by rat pituitaries in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215673"} {"pmid": "4215674", "title": "Studies on the influence of carboxyl-terminal amino acid residues on the activity and stability of human erythrocyte carbonic anhydrase B.", "content": "Studies on the influence of carboxyl-terminal amino acid residues on the activity and stability of human erythrocyte carbonic anhydrase B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215674"} {"pmid": "4215675", "title": "Formation of D-alanyl-D-alanine and D-alanine from UDPMurNAc-L-Ala-D-isoGlu-L-Lys-D-Ala-D-Ala by extracts of Staphylococcus aureus and Streptococcus faecalis.", "content": "Formation of D-alanyl-D-alanine and D-alanine from UDPMurNAc-L-Ala-D-isoGlu-L-Lys-D-Ala-D-Ala by extracts of Staphylococcus aureus and Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215675"} {"pmid": "4215676", "title": "Isolation and characterization of allophycocyanin II from the thermophilic blue-green alga Mastigocladus laminosus Cohn.", "content": "Isolation and characterization of allophycocyanin II from the thermophilic blue-green alga Mastigocladus laminosus Cohn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215676"} {"pmid": "4215677", "title": "Immunological studies on the sigma subunit of the RNA polymerase from vegetative and sporulating cells of Bacillus subtilis.", "content": "Immunological studies on the sigma subunit of the RNA polymerase from vegetative and sporulating cells of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215677"} {"pmid": "4215678", "title": "Oxygen binding properties of Colus gracilis haemocyanin and its subunits.", "content": "Oxygen binding properties of Colus gracilis haemocyanin and its subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215678"} {"pmid": "4215679", "title": "Carbonic anhydrase-aromatic sulfonamide complexes, a resonance Raman study.", "content": "Carbonic anhydrase-aromatic sulfonamide complexes, a resonance Raman study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215679"} {"pmid": "4215680", "title": "Correlation between pyocin-sensitivity and 2-amino sugar composition of Pseudomonas aeruginosa.", "content": "Correlation between pyocin-sensitivity and 2-amino sugar composition of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215680"} {"pmid": "4215681", "title": "Computer-based auditory neurophysiology laboratory.", "content": "Computer-based auditory neurophysiology laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215681"} {"pmid": "4215682", "title": "Induction of minute mutations in Drosophila by x-rays.", "content": "Induction of minute mutations in Drosophila by x-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215682"} {"pmid": "4215683", "title": "Genetic (h-2) dependence of the duration of splenomegaly induced by Brucella abortus.", "content": "Genetic (h-2) dependence of the duration of splenomegaly induced by Brucella abortus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215683"} {"pmid": "4215684", "title": "Laboratory testing of some organic insecticides against Zyginidia quyumi (Ahmed) Typhlocybinae: (Cidadellidae) on maize.", "content": "Laboratory testing of some organic insecticides against Zyginidia quyumi (Ahmed) Typhlocybinae: (Cidadellidae) on maize.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215684"} {"pmid": "4215686", "title": "The status of transplantation of the pancreas and pancreatic tissues as a cure for diabetes.", "content": "The status of transplantation of the pancreas and pancreatic tissues as a cure for diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215686"} {"pmid": "4215685", "title": "Protective antigens in bovine pasteurellosis.", "content": "Protective antigens in bovine pasteurellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215685"} {"pmid": "4215687", "title": "Influence of nifedipine on the effort tolerance test in angina pectoris. Comparison with placebo and trinitroglycerine.", "content": "Influence of nifedipine on the effort tolerance test in angina pectoris. Comparison with placebo and trinitroglycerine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215687"} {"pmid": "4215688", "title": "Nifedipine in angina pectoris. A multicentric clinical trial.", "content": "Nifedipine in angina pectoris. A multicentric clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215688"} {"pmid": "4215690", "title": "Phenotypic properties of R factors of Pseudomonas aeruginosa: R factors readily transferable between Pseudomonas and the Enterobacteriaceae.", "content": "Phenotypic properties of R factors of Pseudomonas aeruginosa: R factors readily transferable between Pseudomonas and the Enterobacteriaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215690"} {"pmid": "4215691", "title": "Phenotypic properties of R factors of Pseudomonas aeruginosa: R factors transferable only in Pseudomonas aeruginosa.", "content": "Phenotypic properties of R factors of Pseudomonas aeruginosa: R factors transferable only in Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215691"} {"pmid": "4215689", "title": "Effect of anti-4-azoquinoline 1-oxide antibody on immunosuppression by 4-hydroxyaminoquinoline 1-oxide.", "content": "Effect of anti-4-azoquinoline 1-oxide antibody on immunosuppression by 4-hydroxyaminoquinoline 1-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215689"} {"pmid": "4215692", "title": "The use of bacteriophages for differentiating plasmids of Pseudomonas aeruginosa.", "content": "The use of bacteriophages for differentiating plasmids of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215692"} {"pmid": "4215694", "title": "Genetic regulation and pattern formation: a study of the yellow locus in Drosophila melanogaster.", "content": "Genetic regulation and pattern formation: a study of the yellow locus in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215694"} {"pmid": "4215693", "title": "Genetic analysis of amidase mutants of Pseudomonas aeruginosa.", "content": "Genetic analysis of amidase mutants of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215693"} {"pmid": "4215695", "title": "Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses.", "content": "Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215695"} {"pmid": "4215696", "title": "Regulation of enzyme activities in Drosophila. II. Characterization of enzyme responses in aneuploid flies.", "content": "Regulation of enzyme activities in Drosophila. II. Characterization of enzyme responses in aneuploid flies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215696"} {"pmid": "4215697", "title": "Rubella antibody titer and IgG concentration in an aging population.", "content": "Rubella antibody titer and IgG concentration in an aging population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215697"} {"pmid": "4215703", "title": "Supersensitivity to pentagastrin in diffuse oesophageal spasm.", "content": "Supersensitivity to pentagastrin in diffuse oesophageal spasm. A 38-year-old patient, complaining of dysphagia and substernal pain of nine months' duration, was found by manometric studies to have diffuse oesophageal spasm. As has similarly been reported for cholinergic agents in achalasia and in some cases of diffuse oesophageal spasm the oesophageal body responded in a hypersensitive fashion to subcutaneous and intravenous injections of pentagastrin. This effect was inhibited by the intravenous administration of atropine and completely abolished by nitroglycerine. When pentagastrin was subcutaneously injected before a barium examination a distortion of the oesophageal contour, described as curling or corkscrew oesophagus, regularly appeared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215703"} {"pmid": "4215704", "title": "Some effects of a microcrystalline collagen preparation on blood.", "content": "Some effects of a microcrystalline collagen preparation on blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215704"} {"pmid": "4215706", "title": "Professor Frantisek Patocka, septuagenarian.", "content": "Professor Frantisek Patocka, septuagenarian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215706"} {"pmid": "4215707", "title": "Effect of rifampicin and free amino acids on replication of DNA in Lactobacillus acidophilus.", "content": "Effect of rifampicin and free amino acids on replication of DNA in Lactobacillus acidophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215707"} {"pmid": "4215709", "title": "Comparative studies of social behavior in Callicebus and Saimiri: behavior of male-female pairs.", "content": "Comparative studies of social behavior in Callicebus and Saimiri: behavior of male-female pairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215709"} {"pmid": "4215708", "title": "Spores of microorganisms. XXV. The effects of histone on the syntheses of macromolecules in germinating and outgrowing spores of Bacillus cereus.", "content": "Spores of microorganisms. XXV. The effects of histone on the syntheses of macromolecules in germinating and outgrowing spores of Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215708"} {"pmid": "4215710", "title": "Male-male competition and infanticide among the langurs (Presbytis entellus) of Abu, Rajasthan.", "content": "Male-male competition and infanticide among the langurs (Presbytis entellus) of Abu, Rajasthan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215710"} {"pmid": "4215711", "title": "Hematological development of the cebus monkey (Cebus albifrons and apella).", "content": "Hematological development of the cebus monkey (Cebus albifrons and apella).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215711"} {"pmid": "4215713", "title": "Harassment of sexual behavior in the stumptail macaque, Macaca arctoides.", "content": "Harassment of sexual behavior in the stumptail macaque, Macaca arctoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215713"} {"pmid": "4215714", "title": "Regulation of biosynthesis of excessive metabolites. XVI. Origin of the terminal group of tetracyclines.", "content": "Regulation of biosynthesis of excessive metabolites. XVI. Origin of the terminal group of tetracyclines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215714"} {"pmid": "4215715", "title": "Biological ensiling of sugarcane tops. VII. Isolation and characteristics of lactic acid bacteria.", "content": "Biological ensiling of sugarcane tops. VII. Isolation and characteristics of lactic acid bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215715"} {"pmid": "4215716", "title": "Immunochemical studies on mannans of the genus Saccharomyces. Group of Saccharomyces sensu stricto species.", "content": "Immunochemical studies on mannans of the genus Saccharomyces. Group of Saccharomyces sensu stricto species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215716"} {"pmid": "4215721", "title": "Properties of a phenolase preparation from cell suspension cultures of parsley.", "content": "Properties of a phenolase preparation from cell suspension cultures of parsley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215721"} {"pmid": "4215724", "title": "Detection and isolation of a second acid stable proteinase inhibitor from human bronchial mucus.", "content": "Detection and isolation of a second acid stable proteinase inhibitor from human bronchial mucus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215724"} {"pmid": "4215725", "title": "Thymus proteases: extraction, distribution, comparison to lymph node proteases and species variation.", "content": "Thymus proteases: extraction, distribution, comparison to lymph node proteases and species variation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215725"} {"pmid": "4215719", "title": "The amino acid sequences of the alpha and beta polypeptide chains of adult hemoglobin of the capuchin monkey (Cebus apella).", "content": "The amino acid sequences of the alpha and beta polypeptide chains of adult hemoglobin of the capuchin monkey (Cebus apella).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215719"} {"pmid": "4215727", "title": "The interaction of native and chemically modified yeast transketolase with a specific antibody.", "content": "The interaction of native and chemically modified yeast transketolase with a specific antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215727"} {"pmid": "4215726", "title": "Alternative pathway for the activation of complement in human serum. Formation and composition of the complex with cobra venom factor that cleaves the third component of complement.", "content": "Alternative pathway for the activation of complement in human serum. Formation and composition of the complex with cobra venom factor that cleaves the third component of complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215726"} {"pmid": "4215720", "title": "Studies on the primary structures of alpha and beta polypeptide chains of adult hemoglobin of the spider monkey (Ateles geoffroyi).", "content": "Studies on the primary structures of alpha and beta polypeptide chains of adult hemoglobin of the spider monkey (Ateles geoffroyi).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215720"} {"pmid": "4215729", "title": "Glucose-6-phosphate 1-epimerase from bakers' yeast: purification, properties and possible biological function.", "content": "Glucose-6-phosphate 1-epimerase from bakers' yeast: purification, properties and possible biological function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215729"} {"pmid": "4215730", "title": "Glycogen metabolism in isolated perfused rat liver.", "content": "Glycogen metabolism in isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215730"} {"pmid": "4215732", "title": "The molecular weight of J chains of human IgM.", "content": "The molecular weight of J chains of human IgM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215732"} {"pmid": "4215733", "title": "Characterization of an acid-stable proteinase inhibitor in human cervical mucus.", "content": "Characterization of an acid-stable proteinase inhibitor in human cervical mucus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215733"} {"pmid": "4215734", "title": "Steroidglucuronyltransferases, V. Formation and hydrolysis of oestrogen glucuronides by the liver, kidney and intestine of the pig.", "content": "Steroidglucuronyltransferases, V. Formation and hydrolysis of oestrogen glucuronides by the liver, kidney and intestine of the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215734"} {"pmid": "4215735", "title": "Biological, immunological and physical investigations on human chorionic gonadotropin.", "content": "Biological, immunological and physical investigations on human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215735"} {"pmid": "4215737", "title": "The changing hospital economy.", "content": "The changing hospital economy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215737"} {"pmid": "4215738", "title": "Drug effects on vision: strategies for study and selected results.", "content": "Drug effects on vision: strategies for study and selected results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215738"} {"pmid": "4215739", "title": "Vitamin B12-like activity in leafy vegetables.", "content": "Vitamin B12-like activity in leafy vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215739"} {"pmid": "4215740", "title": "The genetic control of T cell-meditated immunity. I. Characterization of a mouse strain whose low responsiveness is inherited as a recessive trait.", "content": "The genetic control of T cell-meditated immunity. I. Characterization of a mouse strain whose low responsiveness is inherited as a recessive trait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215740"} {"pmid": "4215741", "title": "The comparative serological response of the chicken, pheasant and quail to a soluble and a particulate antigen.", "content": "The comparative serological response of the chicken, pheasant and quail to a soluble and a particulate antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215741"} {"pmid": "4215742", "title": "Quantification and distribution of chicken immunoglobulins IgA, IgM and IgG in serum and secretions.", "content": "Quantification and distribution of chicken immunoglobulins IgA, IgM and IgG in serum and secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215742"} {"pmid": "4215743", "title": "Protection against Toxoplasma gondii in mice immunized with Toxoplasma cell fractions, RNA and synthetic polyribonucleotides.", "content": "Protection against Toxoplasma gondii in mice immunized with Toxoplasma cell fractions, RNA and synthetic polyribonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215743"} {"pmid": "4215744", "title": "Surface immunoglobulin of a mouse T-cell lymphoma.", "content": "Surface immunoglobulin of a mouse T-cell lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215744"} {"pmid": "4215745", "title": "Red cell Fc receptors and their participation in the passive haemagglutination mediated by non-precipitating antibodies.", "content": "Red cell Fc receptors and their participation in the passive haemagglutination mediated by non-precipitating antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215745"} {"pmid": "4215747", "title": "Formation of salicylic acid from naphthalene by microorganisms: Part I. Studies on isolation, characterization & growth of bacterial isolates utilizing naphthalene.", "content": "Formation of salicylic acid from naphthalene by microorganisms: Part I. Studies on isolation, characterization & growth of bacterial isolates utilizing naphthalene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215747"} {"pmid": "4215746", "title": "Studies on the specificities of two IgM lambda cold agglutinins.", "content": "Studies on the specificities of two IgM lambda cold agglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215746"} {"pmid": "4215748", "title": "Formation of salicylic acid from naphthalene by microorganisms: Part II. Factors affecting salicylic acid accumulation.", "content": "Formation of salicylic acid from naphthalene by microorganisms: Part II. Factors affecting salicylic acid accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215748"} {"pmid": "4215749", "title": "Epizootiology of Kyasanur Forest Disease in wild monkeys of Shimoga district, Mysore State (1957-1964).", "content": "Epizootiology of Kyasanur Forest Disease in wild monkeys of Shimoga district, Mysore State (1957-1964).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215749"} {"pmid": "4215750", "title": "Studies on foetomaternal haemorrhage (FMH). Part I: Factors affecting foetomaternal haemorrhage.", "content": "Studies on foetomaternal haemorrhage (FMH). Part I: Factors affecting foetomaternal haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215750"} {"pmid": "4215751", "title": "Studies on foetomaternal haemorrhage (FMH). Part II. The role of placental pathology in foetomaternal haemorrhage.", "content": "Studies on foetomaternal haemorrhage (FMH). Part II. The role of placental pathology in foetomaternal haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215751"} {"pmid": "4215752", "title": "Improved cell yield from monkey kidneys by using versene and trypsin.", "content": "Improved cell yield from monkey kidneys by using versene and trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215752"} {"pmid": "4215753", "title": "Studies on the antibody response of a formalin inactivated Kyasanur Forest Disease Virus vaccine in langurs \"Presbytis entellus\".", "content": "Studies on the antibody response of a formalin inactivated Kyasanur Forest Disease Virus vaccine in langurs \"Presbytis entellus\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215753"} {"pmid": "4215754", "title": "Significant bacteriuria in apparently healthy young adults.", "content": "Significant bacteriuria in apparently healthy young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215754"} {"pmid": "4215755", "title": "Mental development of children with severe protein calorie malnutrition in the past anbd present.", "content": "Mental development of children with severe protein calorie malnutrition in the past anbd present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215755"} {"pmid": "4215756", "title": "Investigation of secretory immunoglobulins in saliva from germfree mice.", "content": "Investigation of secretory immunoglobulins in saliva from germfree mice. We investigated the effect of oral immunization on the serum and salivary immunoglobulin levels in axenic and conventional NIH mice. Specific antibacterial and antifungal antibodies were measured by passive hemagglutination, and differences in the immunoglobulin classes were measured by radial immunodiffusion. After an oral immunization regimen with either intact Escherichia coli or Candida albicans, a significant increase in specific antibody above the base-line reciprocal titer of 32 was observed in conventional mouse saliva. Saliva from axenic mice immunized with the formalized microorganisms yielded reciprocal antibody titers of 256, as compared with an absence of specific antibodies in control animals. Assay of the sera of both groups of immunized mice revealed no increase in antibody levels specific for E. coli lipopolysaccharide or Candidin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215756"} {"pmid": "4215757", "title": "Immunological study of typhoid: immunoglobulins, C3, antibodies, and leukocyte migration inhibition in patients with typhoid fever and TAB-vaccinated individuals.", "content": "Immunological study of typhoid: immunoglobulins, C3, antibodies, and leukocyte migration inhibition in patients with typhoid fever and TAB-vaccinated individuals. The development of humoral and cell-mediated immune responses to Salmonella typhi antigens and immunoglobulin and C(3) levels were determined in patients suffering from typhoid fever, TAB-vaccinated individuals, and appropriate controls. In 45 patients with typhoid, a significant elevation of immunoglobulin M (IgM) level was noted from the first week of illness onwards. Eighteen TAB-vaccinated persons also showed a significant elevation of IgM levels. In typhoid sera, the anti-O and anti-H antibodies were mostly 2-mercaptoethanol (2-ME) sensitive. The rise of IgM level correlated well with the 2-ME-sensitive anti-O and anti-H antibodies seen in typhoid patients. The anti-O antibodies in the TAB-vaccinated group were almost entirely 2-ME sensitive, but both 2-ME-sensitive and -resistant anti-H antibodies were detected in the TAB group. A marked increas in C(3) level was also noted in patients with typhoid. The cell-mediated immunity (CMI), as measured by leukocyte migration inhibition tests, was demonstrable in 15 of 22 patients with typhoid. On the other hand, only 8 of the 20 normal subjects, 5 of the 16 fever control cases, and 6 of the 18 TAB-vaccinated individuals gave a positive CMI. The latter three groups were comparable with each other but were significantly different from the typhoid patients. It was concluded that TAB-vaccination did not induce CMI even though it induced the development of antibodies, the latter being comparable with those of the patients with typhoid. The significance of these findings is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215757"} {"pmid": "4215758", "title": "Some properties of precipitating antigens associated with infectious bursal disease virus.", "content": "Some properties of precipitating antigens associated with infectious bursal disease virus. Infection of the bursa of Fabricius and chicken embryo fibroblast cell cultures with avian infectious bursal disease virus resulted in production of a number of virus-induced antigens. The antigens were specific, forming three precipitin lines by immunodiffusion with antiserum (designated PA-1, -2, and -3). To separate immunoprecipitin from the remaining viral particles, two (PA-1 and PA-3) were partially purified by subjection to two cycles of diethylaminoethyl-cellulose chromatography and filtration through a column of Sephadex G-150 gel. The precipitating antigen, PA-1, was found to migrate most slowly through the agar gel, remaining serologically active after treatment with heating (56 C for 1 h), trypsin, lipolytic solvents, deoxyribonuclease, and ribonuclease. Its density was 1.27 g/ml. Morphologically the antigen displayed a doughnut-shaped structure 8 to 12 nm in size. PA-3 migrated most rapidly through the agar gel. It was destroyed by treatment with heating and trypsin but not with lipolytic solvents, deoxyribonuclease, and ribonuclease. Density was about 1.25 g/ml. This suggests that the antigen is a part of viral structural components. PA-2 migrated through agar gel at a rate between that of PA-1 and PA-3. Because of its low concentration, PA-2 was not further characterized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215758"} {"pmid": "4215760", "title": "Interaction of staphylococcal exfoliative toxin with concanavalin A.", "content": "Interaction of staphylococcal exfoliative toxin with concanavalin A. Treatment of mouse embryo fibroblasts (MEF) grown in vitro with purified staphylococcal exfoliative toxin (ET) increased the concanavalin A (Con A) agglutinability of MEF 3.5-fold over control cells. Possible explanations for this phenomenon were investigated. ET lacked proteolytic activity on denatured casein. Con A, however, was found to interact directly with ET as evidenced by the formation of precipitation in an agar gel diffusion plate and in increased turbidity in solution. This interaction was inhibited by alpha-methyl-d-glucopyranoside. The ability of Con A to precipitate with ET suggests that the toxin contains a carbohydrate component and that the carbohydrate associated with ET is branched rather than linear. An analysis of a purified preparation of ET indicated the presence of 9% carbohydrate and no lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215760"} {"pmid": "4215759", "title": "Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes.", "content": "Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes. The nature of the phagocytic stimulus determines the degree of degranulation. Specifically, immune complexes induced more degranulation than did antigen or antibody alone. The release of constituents from the two granule classes represented independent phenomena. Relatively more of the specific granule proteins were released into the medium during phagocytosis, whereas more of the azurophil proteins were associated with the phagosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215759"} {"pmid": "4215761", "title": "Immunological analysis of glycolipids and lipopolysaccharides derived from various mycoplasmas.", "content": "Immunological analysis of glycolipids and lipopolysaccharides derived from various mycoplasmas. The lipids and lipopolysaccharides of five mycoplasmas were examined for complement-fixing activity to antimembrane rabbit sera. Total glycolipid fractions and the aqueous phenol fractions (lipopolysaccharides) from the membranes of Acholeplasma laidlawii, A. modicum, A. axanthum, and Mycoplasma neurolyticum exhibited significant antigenic activity. The glycolipids and phosphoglycolipids from Thermoplasma acidophilum were either anticomplementary or did not react due to their extreme hydrophobic nature. High activity was found using the lipopolysaccharide of T. acidophilum. The pure glycolipids and phosphoglycolipids of the Acholeplasma and Mycoplasma species also exhibited significant complement-fixing activity. Acylation of the sugar residues of these lipids reduced or negated complement-fixing activity. Double cross-reactions between the glycolipids of A. laidlawii and A. modicum appeared to be due to mono- and diglucosyl diglycerides of identical structure. Specificity of glycolipid structure was noted by the absence of cross-reactions between A. laidlawii and M. neurolyticum, the glycolipids of which differ only in the nature of the glucose linkages. The existence of lipopolysaccharides in the membranes of mycoplasmas and their complement-fixing activity in the presence of antimembrane sera suggest their possible importance as specific antigenic determinants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215761"} {"pmid": "4215763", "title": "Modoc viral infections in the deer mouse Peromyscus maniculatus.", "content": "Modoc viral infections in the deer mouse Peromyscus maniculatus. The pathogenesis of Modoc virus and its mechanism of transmission were investigated in Peromyscus maniculatus gambeli (deer mouse) as a model to understand the natural history of this virus. Animals were readily infected by the intranasal or subcutaneous route of inoculation. Virus could be detected by direct isolation techniques in many organs and body fluids during the first 7 to 9 days after intranasal inoculation. Increases in viral titers were detectable first in lungs and then the spleen, salivary-submaxillary glands, and lymph nodes. Viremias were low titered and ephemeral. Virus was recovered from urine and throat swabs 4 to 6 days and 4 to 7 days after inoculation, respectively. Serum dilution neutralization, hemagglutination inhibition, or complement fixation antibodies were detected in sera of some animals 13 days after infection and in all animals after 20 days. Antibodies persisted for the 168-day period of observation. Persistent viral infection was demonstrable by in vitro culturing of lungs or pooled lungs, salivary glands, and kidneys from 14 of 69 mice that were sacrificed from 1 to 6 months after intranasal inoculation. Attempts to demonstrate horizontal or vertical transmission of Modoc virus among mice were generally unsuccessful. Female deer mice infected with virus before mating passed maternal antibodies to their young.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215763"} {"pmid": "4215762", "title": "Opsonin system of the group B streptococcus.", "content": "Opsonin system of the group B streptococcus. The opsonization by polymorphonuclear leukocytes of group B streptococcal serotypes associated with neonatal sepsis and delayed meningitis was studied. A specific BIa opsonizing antibody (not related to the antipolysaccharide typing antibody) was present in only 10% of the population tested. Serotype BIa was not opsonized in the absence of this specific antibody. BIa antibody specificity was demonstrated by macroagglutination and absorption with BIa streptococci and extracts, but not by gel diffusion. The binding of complement by the BIa opsonin increased the mean phagocytic activity by 60%; complement was manifested via the classic and/or alternate C3-related pathway, but seldom by both concurrently. Serotypes BIb, BIc, BII, and BIII were naturally and nonspecifically opsonized in 95% of the human and baboon sera or plasma tested. Although similar levels of opsonization were present in hyperimmune rabbit sera, heat inactivation and homologous bacterial absorption did not reduce the level of phagocytic activity in the rabbit, human, or primate groups studied. These immunological studies confirmed previous findings that serotype BIa presents a serious hazard for neonatal sepsis, with a nearly 100% mortality. Exclusive isolation of BIII in delayed meningitis suggests that ingestion and subsequent killing by polymorphonuclear leukocytes of type III may differ from the other serotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215762"} {"pmid": "4215765", "title": "Phase transition of gonococci in mammalian cell cultures.", "content": "Phase transition of gonococci in mammalian cell cultures. Neisseria gonorrhoeae was cultivated in mammalian cell cultures in an effort to determine if this environment will elicit a T4 --> T1 transition. Of four avirulent (T4) isolates tested, only one, H4, yielded T1 colonies. This change was consistently obtained in HeLa, WI-38, and MK2 cells, even when the multiplicity of the gonococcal infection was less than 1 per culture. Growth of the gonococci took place primarily on the surface of the cells, as demonstrated by light and electron microscopy, but occasional bacteria were undoubtedly intracellular. T1 colonies were seen at 24 h and were the major population at 48 h. This shift was favored by the presence of viable cells, since smaller yields of T1 were obtained when the cells were irradiated or heat inactivated. It was also favored by low pH, since T1 recovery was reduced when the buffering capacity of the medium was increased. Although the results suggest that T1 gonococci derived from H4 have a selective advantage over T4 in cell cultures, this is not true of all T1 and T4 colony types. F62 T4, which does not undergo a T4 --> T1 shift, propagated as well as T1 in HeLa cell cultures. The change in colony type of strain H4 to T1 was accompanied by formation of pili and by gain in capacity for deoxyribonucleic acid-mediated transformation. It is concluded that gonococci can undergo T4 --> T1 phase transition in mammalian cell cultures, but this property is not retained by all strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215765"} {"pmid": "4215764", "title": "Persistent infection of BSC-1 cells by defective measles virus derived from subacute sclerosing panencephalitis.", "content": "Persistent infection of BSC-1 cells by defective measles virus derived from subacute sclerosing panencephalitis. A line of cells (IP-3), persistently infected with defective measles virus, was developed from co-cultures of subacute sclerosing panencephalitis-derived brain cells with monkey kidney cells (BSC-1). The line, carried for more than 45 serial passages, produced neither infectious virus nor hemagglutinin. Cultures consistently displayed a cycling focal cytopathic pattern of infection characterized by formation of syncytia, necrosis, and plaques followed by healing. Fluorescent measles antigen was present in damaged areas only, especially in syncytia. The development of syncytia was suppressed by measles antibody. Syncytia were lysed by antibody plus rabbit complement. A variant noncytopathic subline (IP-3-Ca) was derived from the 16th passage. Infectious virus was not detected. Cells were minimally positive for hemadsorption. Fluorescent measles antigen was present in all cells. Co-cultures of IP-3-Ca cells with normal BSC-1 cells developed massive syncytia and extensive destruction. The IP-3-Ca cells multiplied in the presence of measles antibodies and were destroyed by antibodies plus complement. The possible relevance of these findings to the pathogenesis of subacute sclerosing panencephalitis is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215764"} {"pmid": "4215766", "title": "Conversion of serotype in Leptospira from hebdomadis to kremastos.", "content": "Conversion of serotype in Leptospira from hebdomadis to kremastos. A mutant of Leptospira serotype hebdomadis, obtained by cultivating hebdomadis in the presence of the homologous immune serum, was serologically identical with kremastos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215766"} {"pmid": "4215767", "title": "Surveillance and monitoring.", "content": "Surveillance and monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215767"} {"pmid": "4215768", "title": "An improved radionuclide distribution profile from a fixed array whole-body counter using a mathematical analysis technique.", "content": "An improved radionuclide distribution profile from a fixed array whole-body counter using a mathematical analysis technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215768"} {"pmid": "4215769", "title": "Application of a coincidence counting technique in a fixed geometry whole-body counter.", "content": "Application of a coincidence counting technique in a fixed geometry whole-body counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215769"} {"pmid": "4215770", "title": "Evaluation of the pituitary-thyroid axis by measuring the response of I-labelled thyroid hormones to TRH.", "content": "Evaluation of the pituitary-thyroid axis by measuring the response of I-labelled thyroid hormones to TRH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215770"} {"pmid": "4215772", "title": "Determination of the optimum window for whole body counting of 47Ca.", "content": "Determination of the optimum window for whole body counting of 47Ca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215772"} {"pmid": "4215771", "title": "The unit dose preparation of 63Zn-EDTA for use in nuclear medicine.", "content": "The unit dose preparation of 63Zn-EDTA for use in nuclear medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215771"} {"pmid": "4215773", "title": "Recent advances in cytochemistry and ultrastructure of cytoplasmic inclusions in Ciliophora (Protozoa).", "content": "Recent advances in cytochemistry and ultrastructure of cytoplasmic inclusions in Ciliophora (Protozoa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215773"} {"pmid": "4215774", "title": "Infectious DNA-protein complex from cells productively infected with simian adenovirus SA7.", "content": "Infectious DNA-protein complex from cells productively infected with simian adenovirus SA7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215774"} {"pmid": "4215776", "title": "Pyroglutamyl-histidyl-prolineamide (TRH). A neurohormone which affects the release and synthesis of prolactin and thyrotropin.", "content": "Pyroglutamyl-histidyl-prolineamide (TRH). A neurohormone which affects the release and synthesis of prolactin and thyrotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215776"} {"pmid": "4215775", "title": "Heterogeneity of human luteinizing hormone. Behavior in radioimmunoassay and radio-ligand-receptor assay systems and evidence for the presence of alpha-subunit in serum.", "content": "Heterogeneity of human luteinizing hormone. Behavior in radioimmunoassay and radio-ligand-receptor assay systems and evidence for the presence of alpha-subunit in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215775"} {"pmid": "4215777", "title": "Human chorionic thyrotropin. Its relationship to thyroid stimulators from chorionic neoplasms and nonendocrine cancers.", "content": "Human chorionic thyrotropin. Its relationship to thyroid stimulators from chorionic neoplasms and nonendocrine cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215777"} {"pmid": "4215778", "title": "Specific immunoassay for quantitative determination of human chymotrypsin.", "content": "Specific immunoassay for quantitative determination of human chymotrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215778"} {"pmid": "4215781", "title": "\"B\" and \"C\" isoenzymes of carboanhydrase in erythrocytes of mother, newborn infant and umbilical cord. Immunofluorescence study.", "content": "\"B\" and \"C\" isoenzymes of carboanhydrase in erythrocytes of mother, newborn infant and umbilical cord. Immunofluorescence study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215781"} {"pmid": "4215783", "title": "Synthesis of 4'-deoxykanamycin and its resistance to kanamycin phosphotransferase II.", "content": "Synthesis of 4'-deoxykanamycin and its resistance to kanamycin phosphotransferase II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215783"} {"pmid": "4215784", "title": "The effect of incubation temperature on the recovery of spores of Bacillus subtilis 8057.", "content": "The effect of incubation temperature on the recovery of spores of Bacillus subtilis 8057.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215784"} {"pmid": "4215785", "title": "Rapid screening for the isolation of mutants of Aspergillus nidulans with increased penicillin yields.", "content": "Rapid screening for the isolation of mutants of Aspergillus nidulans with increased penicillin yields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215785"} {"pmid": "4215786", "title": "The immunopurification of tetanus toxoid.", "content": "The immunopurification of tetanus toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215786"} {"pmid": "4215787", "title": "Intra- and interspecies variability of vertebrate high-pressure neurological syndrome.", "content": "Intra- and interspecies variability of vertebrate high-pressure neurological syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215787"} {"pmid": "4215789", "title": "Genetic basis of nutritional requirements in Lactobacillus casei.", "content": "Genetic basis of nutritional requirements in Lactobacillus casei. In a study of the genetic basis of multiple nutritional requirements in Lactobacillus casei, systematic attempts were made to isolate mutants that can grow in the absence of a specific nutrient required by the parental organism. Such mutants have successfully been isolated with respect to seven of twelve amino acids (aspartic acid, leucine, isoleucine, lysine, methionine, serine, and threonine) and three of four vitamins (pantothenic acid, nicotinic acid, and pyridoxal) tested, after extensive screenings employing various mutagens. Mutants that can grow without tryptophan were not isolated, but those that can grow on anthranilate or indole as well as on tryptophan were obtained at a frequency expected for single-step mutations. Activity of tryptophan synthetase was demonstrated in extracts of these anthranilate-utilizing mutants, but not in the parental strain. These results suggest that the multiple nutritional requirements of L. casei are often, if not always, due to one or a few small lesions such as base substitution mutations rather than large deletions affecting the genes involved in each biosynthetic pathway. The data would also imply that many of the biosynthetic pathways that are not fully functional in L. casei were active at one time and became nonfunctional during evolution of the present species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215789"} {"pmid": "4215782", "title": "Current concepts of patient motivation toward long term oral hygiene: a literature review.", "content": "Current concepts of patient motivation toward long term oral hygiene: a literature review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215782"} {"pmid": "4215790", "title": "Active transport of D-alanine and related amino acids by whole cells of Bacillus subtilis.", "content": "Active transport of D-alanine and related amino acids by whole cells of Bacillus subtilis. Whole cells of Bacillus subtilis transported d-alanine and l-alanine by two different systems. The high-affinity system (K(m) of 1 muM and V(max) of 0.6 to 0.8 nmol/min per mg of protein) was specific for the two stereoisomers of alanine. The low-affinity system (K(m) of 10 muM for l-alanine and 20 muM for d-alanine and glycine) had a V(max) of 5 to 12 nmol/min per mg of protein. This system transported glycine, d-cycloserine, and d-serine, in addition to d- and l-alanine. Azide inhibited the uptake of these amino acids and caused the efflux of d-alanine from preloaded cells. These data suggest that transport of these amino acids is energized by the electron transport chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215790"} {"pmid": "4215791", "title": "Comparative studies on induction of sporulation and synthesis of inducible enzymes in Bacillus subtilis.", "content": "Comparative studies on induction of sporulation and synthesis of inducible enzymes in Bacillus subtilis. An attempt was made to determine whether sporulation and inducible enzyme synthesis in Bacillus subtilis are controlled by the same mechanism of catabolite repression. By the use of a thymine-requiring strain, it has been shown that, whereas sporulation remained repressed unless chromosome replication proceeded to completion, the induction of the enzymes histidase, sucrase, and alpha-glucosidase proceeded quite normally in the absence of continued deoxyribonucleic acid synthesis. It is concluded that the mechanism for overcoming the repression of sporulation differs qualitatively from that involved in overcoming the repression of inducible enzyme synthesis. Attempts to isolate pleiotropic mutants that would provide additional support for this contention were unsuccessful. A pleiotropic mutant deficient in phosphoenolpyruvate-dependent phosphotransferase activity sporulated quite well, whereas a mutant presumed deficient in glutamate synthetase sporulated poorly under all conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215791"} {"pmid": "4215792", "title": "Mis-regulation of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase does not account for growth inhibition by phenylalanine in Agmenellum quadruplicatum.", "content": "Mis-regulation of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase does not account for growth inhibition by phenylalanine in Agmenellum quadruplicatum. The growth of the blue-green bacterium, Agmenellum quadruplicatum, is inhibited in the presence of l-phenylalanine. This species has a single, constitutively synthesized 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthetase. l-Phenylalanine inhibits DAHP synthetase non-competitively with respect to both substrate reactants. Other aromatic amino acids do not inhibit the activity of DAHP synthetase. A common expectation for branch-point enzymes such as DAHP synthetase is a balanced pattern of feedback control by all of the ultimate end products. It seemed likely that growth inhibition might equate with defective regulation within the branched aromatic pathway. Accordingly, the possibility was examined that mis-regulation of DAHP synthetase by l-phenylalanine in wild-type cells causes starvation for precursors of the other aromatic end products. However, the molecular basis for growth inhibition cannot be attributed to l-phenylalanine inhibition of DAHP synthetase for the following reasons: (i) DAHP synthetase enzymes from l-phenylalanine-resistant mutants are more, rather than less, sensitive to feedback inhibition by l-phenylalanine. (ii) Shikimate not only fails to antagonize inhibition, but is itself inhibitory. (iii) Neither the sensitivity nor the completeness of l-phenylalanine inhibition of the wild-type enzyme in vitro appears sufficient to account for the potent inhibition of growth in vivo by l-phenylalanine. The dominating effect of l-phenylalanine in the control of DAHP synthetase appears to reflect a mechanism that prevents rather than causes growth inhibition by l-phenylalanine. The alteration of the control of DAHP synthetase in mutants selected for resistance to growth inhibition by l-phenylalanine did indicate that the cause for this metabolite vulnerability can be localized within the aromatic amino acid pathway. Apparently, an aromatic intermediate (between shikimate and the end products) accumulates in the presence of l-phenylalanine, causing toxicity by some unknown mechanism. It is concluded that phenylpyruvate, potentially formed by transamination of l-phenylalanine, is an unlikely cause of growth inhibition. Although several significant questions remain unanswered, our results suggest that single-effector control of DAHP synthetase, the first regulatory enzyme activity of a branched pathway, may be more appropriate than it would seem a priori.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215792"} {"pmid": "4215793", "title": "Transformation of Bacillus subtilis in alpha-amylase productivity by deoxyribonucleic acid from B. subtilis var. amylosacchariticus.", "content": "Transformation of Bacillus subtilis in alpha-amylase productivity by deoxyribonucleic acid from B. subtilis var. amylosacchariticus. Deoxyribonucleic acid (DNA) of Bacillus subtilis var. amylosacchariticus showed almost the same ability as B. subtilis Marburg to induce transfer of several genetic markers in DNA-mediated transformation. DNA-DNA hybridization data also showed an intimate relationship between the two strains. Genetic elements involved in the production of extracellular alpha-amylase (EC 3.2.1.1.) in B. subtilis var. amylosacchariticus were studied by using DNA-mediated transformation. Two Marburg derivatives, NA20(amyR2) and NA20-22(amyR1), produced about 50 and 10 U of alpha-amylase per mg of cells, respectively, whereas B. subtilis var. amylosacchariticus produced as much as 150 U of the enzyme per mg of cells. When B. subtilis var. amylosacchariticus was crossed with strain NA20-22 as recipient, transformants that acquired high alpha-amylase productivity (about 50 U/mg of cells) were obtained. Genetic analysis revealed that a regulator gene (amyR) for alpha-amylase synthesis was found in B. subtilis var. amylosacchariticus, as in the case of B. natto 1212 (amyR2) and B. subtilis Marburg (amyR1). The allele was designated amyR3; it is phenotypically indistinguishable from amyR2, but is readily distinguishable from amyR1. The presence of amyR3 was not sufficient for an organism to render production of an exceptional amount of alpha-amylase. Extra-high alpha-amylase producers could be obtained by crossing B. subtilis var. amylosacchariticus as donor with strain NA20 as recipient. The transformants produced the same or even greater amounts of the enzyme than the donor strain. Results suggest the presence of another gene that is involved in the production of the exceptional amount of alpha-amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215793"} {"pmid": "4215794", "title": "Genetic and biophysical study of R plasmids conferring sulfonamide resistance in Shigella strains isolated in 1952 and 1956.", "content": "Genetic and biophysical study of R plasmids conferring sulfonamide resistance in Shigella strains isolated in 1952 and 1956. The conjugative plasmids determining sulfonamide resistance in five Shigella strains, each isolated from a different patient, have been characterized. One S. flexneri 2a strain, isolated in 1952, harbored an fi(+) plasmid of molecular weight 53 x 10(6), which specified synthesis of F-like pili and bore determinants for sulfonamide resistance (Su) and bacteriocinogeny (Col). This plasmid was compatible with plasmids of groups F(I), F(II), I(alpha), and P. A second S. flexneri 2a strain isolated in 1952 harbored an fi(-) plasmid of molecular weight 59 x 10(6), bearing the Su determinant and compatible with all plasmids tested. This strain also harbored an fi(+) group-F(II) plasmid of molecular weight 42 x 10(6), which bore the Col determinant and specified synthesis of F-like pili. Three S. dysenteriae 2 strains isolated in 1956 carried apparently identical fi(-) plasmids of molecular weight 58 x 10(6), which bore the Su determinant, could form transconjugants in Pseudomonas but not in Proteus, and were incompatible with the P-group plasmid RP4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215794"} {"pmid": "4215796", "title": "Relationship between lysogeny, spontaneous induction, and transformation efficiencies in Bacillus subtilis.", "content": "Relationship between lysogeny, spontaneous induction, and transformation efficiencies in Bacillus subtilis. The low transformation efficiency of Bacillus subtilis 168 lysogenic for phages ø105 or SPO2 is shown to result from the induction of lytic phage replication in competent cells. Lysogenic competent cells have a higher rate of spontaneous prophage induction than noncompetent cells. Mutants of ø105 and SPO2 which form lysogens resistant to spontaneous induction were isolated, and these lysogens exhibited higher transformation levels than those formed by wild-type phage. These results suggest that the physiological state of competence in B. subtilis promotes prophage derepression leading to cell death and the loss of potential transformants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215796"} {"pmid": "4215795", "title": "Existence of a free form of a specific membrane lipoprotein in gram-negative bacteria.", "content": "Existence of a free form of a specific membrane lipoprotein in gram-negative bacteria. The existence of a free form of a specific lipoprotein of molecular weight 7,200 was examined in the envelopes of several gram-negative bacteria. When the envelope proteins were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis, distinct peaks were observed in Salmonella typhimurium, Serratia marcescens, and Pseudomonas aeruginosa at the same position as the free form of the lipoprotein of Escherichia coli. However, the peak was not observed in Proteus mirabilis. The protein at the peak in S. typhimurium was shown to contain little or no histidine as expected from the amino acid composition of the lipoprotein. Furthermore, antiserum against the highly purified lipoprotein from E. coli was shown to react with the proteins from S. typhimurium and S. marcescens and to form the specific immunoprecipitates. In contrast, the protein from P. aeruginosa did not react with the antiserum at all. Thus, it is concluded that S. typhimurium and S. marcescens have the free form of the lipoprotein in their envelopes as does E. coli. P. aeruginosa contains a protein of the same size as the lipoprotein, but it is not certain whether the protein is the same structural protein as the lipoprotein from E. coli. P. mirabilis may not have any free form of the lipoprotein, may have it in a very small amount, or may have a lipoprotein of different molecular weight serving the same function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215795"} {"pmid": "4215798", "title": "Requirement of deoxyribonucleic acid synthesis for microcycle sporulation in Bacillus megaterium.", "content": "Requirement of deoxyribonucleic acid synthesis for microcycle sporulation in Bacillus megaterium. Bacillus megaterium cells have been examined during outgrowth for their macromolecular content, ability to undergo microcycle sporulation, the time of their growth division, the time of deoxyribonucleic acid (DNA) replication initiation, and their ability to synthesize DNA after transfer to sporulation medium. The increase in total DNA content of the cells increased discontinuously beginning at 90 min. Thymidine incorporation became insensitive to chloramphenicol between 90 and 105 min of outgrowth. At 90 min the cells acquired the ability to undergo microcycle sporulation and the degree of sporulation depended on the time spent in outgrowth, with maximal sporulation occurring at 180 min. During outgrowth, cells underwent one synchronous growth division beginning at 225 min and ending at 270 min. Outgrowing cells were not able to continue DNA synthesis after transfer to sporulation medium. The data suggest that DNA replication starts before cells are able to undergo microcycle sporulation; however, the initiation of replication may not be the only requirement for microcycle sporulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215798"} {"pmid": "4215799", "title": "Developmental modulation of deoxyribonucleic acid-binding proteins of Bacillus subtilis during sporulation stages.", "content": "Developmental modulation of deoxyribonucleic acid-binding proteins of Bacillus subtilis during sporulation stages. The isolation of deoxyribonucleic acid (DNA)-binding proteins from various stages of growth and sporulation of Bacillus subtilis is described. After adsorption and elution from phosphocellulose, the proteins were fractionated according to their ability to adsorb to denatured calf thymus DNA-cellulose or native B. subtilis DNA-cellulose. The proteins were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and purification was monitored by a nitrocellulose filter binding assay. Approximately 1% of the proteins in the crude extract adsorbed to denatured calf thymus DNA-cellulose and 0.1% adsorbed to native B. subtilis DNA-cellulose. Each class of proteins varied qualitatively and quantitatively as sporulation proceeded. Several proteins from the exponential phase of growth that bound to denatured DNA were lost by T(0), whereas at T(5) new polypeptides appeared. Fewer changes in the profile of proteins with affinity for native DNA were observed between exponential phase and T(0); however, the dominant species in these eluates were clearly different.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215799"} {"pmid": "4215797", "title": "Natural messenger ribonucleic acid-directed cell-free protein-synthesizing system of Bacillus subtilis.", "content": "Natural messenger ribonucleic acid-directed cell-free protein-synthesizing system of Bacillus subtilis. A very active in vitro protein-synthesizing system has been developed from Bacillus subtilis. High activity in the extracts is dependent upon precautions taken to reduce proteolytic activity. Endogenous, exogenous natural and synthetic messenger ribonucleic acids (RNAs) are translated by the system. The activity of the B. subtilis system has been compared to that of the Escherichia coli system. With either SPO1 RNA or polyuridylic acid, the activities of the two systems were very similar. Electrophoresis of the products synthesized in vitro by the two systems primed with SPO1 RNA yields similar radioactive profiles. The major bands of radioactivity correspond to proteins of molecular weight between 15,000 and 40,000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215797"} {"pmid": "4215800", "title": "Effect of pH on the proportions of polar lipids, in chemostat cultures of Bacillus subtilis.", "content": "Effect of pH on the proportions of polar lipids, in chemostat cultures of Bacillus subtilis. Significant changes in the relative proportions of the individual polar lipids of two strains of Bacillus subtilis were observed when the pH of their chemostat cultures was varied. In phosphate- and magnesium-limited cultures of B. subtilis var. niger NCIB 8058. lysylphosphatidylglycerol was present in higher proportions at low pH (5.1) than at neutral pH. With magnesium-limited cultures of this strain harvested at pH 8.0, lysylphosphatidylglycerol and phosphatidylethanolamine were not detected. Phosphate-limited cultures of B. subtilis NCIB 3610 contained no phosphatidylethanolamine or lysylphosphatidylglycerol at neutral pH, but at low pH (5.1) both these lipids were present in substantial proportions. The proportions of phosphatidylglycerol in actively dividing cells of chemostat cultures of bacilli were always greater than those of lysylphosphatidylglycerol. The reverse is commonly found in batch cultures of bacilli and staphylococci harvested at low pH. Changes in the proportions of the other polar lipids present in these bacilli (diphosphatidylglycerol and diglucosyl diacylglycerol) with pH were also noted. Certain cultures of both strains of B. subtilis contained small proportions of a peptidolipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215800"} {"pmid": "4215801", "title": "Structure and immunological properties of D-arabino-D-galactans isolated from cell walls of Mycobacterium species.", "content": "Structure and immunological properties of D-arabino-D-galactans isolated from cell walls of Mycobacterium species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215801"} {"pmid": "4215803", "title": "Cell-surface changes of phosphate-deficient Escherichia coli as characterized by increased stability and decreased concanavalin A-agglutinability of the spheroplast.", "content": "Cell-surface changes of phosphate-deficient Escherichia coli as characterized by increased stability and decreased concanavalin A-agglutinability of the spheroplast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215803"} {"pmid": "4215802", "title": "Immobilized enzymes. I. Immobilization of carboxypeptidase CN, a preparation from Citrus natsudaidai Hayata.", "content": "Immobilized enzymes. I. Immobilization of carboxypeptidase CN, a preparation from Citrus natsudaidai Hayata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215802"} {"pmid": "4215804", "title": "The role of tyrosine residue of bacterial liquefying alpha-amylase in the enzymatic hydrolysis of linear substrates as studied by chemical modification with acetic anhydride.", "content": "The role of tyrosine residue of bacterial liquefying alpha-amylase in the enzymatic hydrolysis of linear substrates as studied by chemical modification with acetic anhydride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215804"} {"pmid": "4215805", "title": "Studies on ribosomal ribonucleic acid from yeast. II. Specific complex of yeast ribosomal RNA.", "content": "Studies on ribosomal ribonucleic acid from yeast. II. Specific complex of yeast ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215805"} {"pmid": "4215806", "title": "The number of subsites in the active site of saccharifying alpha-amylase from Bacillus subtilis.", "content": "The number of subsites in the active site of saccharifying alpha-amylase from Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215806"} {"pmid": "4215807", "title": "Gel chromatography and gel electrophoresis of histones in denaturing solvents. Limited dependence on molecular weight.", "content": "Gel chromatography and gel electrophoresis of histones in denaturing solvents. Limited dependence on molecular weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215807"} {"pmid": "4215808", "title": "Studies on cellulase produced by the phytopathogens. Purification and enzymatic properties of cellulase of Fusarium moniliforme.", "content": "Studies on cellulase produced by the phytopathogens. Purification and enzymatic properties of cellulase of Fusarium moniliforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215808"} {"pmid": "4215809", "title": "Partial purification and some properties of pyruvate-aspartic semialdehyde condensing enzyme from sporulating Bacillus subtilis.", "content": "Partial purification and some properties of pyruvate-aspartic semialdehyde condensing enzyme from sporulating Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215809"} {"pmid": "4215810", "title": "Studies on cathepsins of rat liver lysosomes. I. Purification and multiple forms.", "content": "Studies on cathepsins of rat liver lysosomes. I. Purification and multiple forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215810"} {"pmid": "4215811", "title": "Difference in the molecular size of hepatic cytosol glycogen synthetase in tadpole and adult frog, Rana catesbeiana.", "content": "Difference in the molecular size of hepatic cytosol glycogen synthetase in tadpole and adult frog, Rana catesbeiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215811"} {"pmid": "4215812", "title": "Affinity chromatography of neutral and alkaline proteases from Bacillus subtilis and of thermolysin.", "content": "Affinity chromatography of neutral and alkaline proteases from Bacillus subtilis and of thermolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215812"} {"pmid": "4215813", "title": "Rat liver alkaline phosphatase. Purification and properties.", "content": "Rat liver alkaline phosphatase. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215813"} {"pmid": "4215815", "title": "Widespread distribution of lysozyme g in egg white of birds.", "content": "Widespread distribution of lysozyme g in egg white of birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215815"} {"pmid": "4215814", "title": "Characterization of vitamin B12-binding proteins isolated from human milk and saliva by affinity chromatography.", "content": "Characterization of vitamin B12-binding proteins isolated from human milk and saliva by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215814"} {"pmid": "4215816", "title": "Relationships among enzymes of the beta-ketoadipate pathway. IV. Muconolactone isomerase from Acinetobacter calcoaceticus and Pseudomonas putida.", "content": "Relationships among enzymes of the beta-ketoadipate pathway. IV. Muconolactone isomerase from Acinetobacter calcoaceticus and Pseudomonas putida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215816"} {"pmid": "4215818", "title": "The regeneration of cilia in partially deciliated Tetrahymena.", "content": "The regeneration of cilia in partially deciliated Tetrahymena. Partial deciliation of Tetrahymena resulted in cells losing 75% of their cilia, with the balance being paralyzed. The paralyzed cilia are resorbed in the first 20 min after partial deciliation, and regeneration of cilia begins before resorption is completed. Inhibition of protein synthesis with cycloheximide does not inhibit ciliary resorption or regeneration, whereas vinblastine sulfate inhibits regeneration but not resorption. Inhibition of regeneration occurs in completely deciliated cells when they are treated with cyclohexmimide or vinblastine sulfate. It is concluded that the resorbing cilia contribute materials which allow regeneration to occur in the absence of protein synthesis. The volume of cilia regenerated in the presence of cycloheximide in partially deciliated cells is greater than the ciliary volume which is resorbed. This suggests the Tetrahymena cells have a pool of ciliary precursors. This pool does not contribute materials for regeneration in completely deciliated cells which are treated with cycloheximide. It is concluded that resorbing cilia in partially deciliated cells contribute materials which potentiate assembly of cilia from the pool of precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215818"} {"pmid": "4215821", "title": "Myonemal contraction of Spirostomum. I. Kinetics of contraction and relaxation.", "content": "Myonemal contraction of Spirostomum. I. Kinetics of contraction and relaxation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215821"} {"pmid": "4215820", "title": "Properties of flagellar \"rigor waves\" formed by abrupt removal of adenosine triphosphate from actively swimming sea urchin sperm.", "content": "Properties of flagellar \"rigor waves\" formed by abrupt removal of adenosine triphosphate from actively swimming sea urchin sperm. Sea urchin sperm were demembranated and reactivated with a solution containing 0.04% Triton X-100 and 0.03 mM ATP. The ATP concentration was then lowered abruptly by diluting the sperm suspension 50-fold into reactivating solution containing no ATP. The flagella of the sperm in the diluted suspension were not motile, but they were bent into a variety of stationary rigor wave forms closely resembling the wave forms occurring at different stages of the flagellar bending cycle during normal movement. The form of these rigor waves was unchanged upon storage for several hours in the presence of dithiothreitol and EDTA. Addition of 1 microM ATP induced slow relaxation of the waves, with most of the sperm becoming partially straightened over a period of about 30 min; somewhat higher concentrations gave a more rapid and complete relaxation. Concentrations of ATP above 10 microM induced resumption of normal beating movements. Addition of ITP, GTP, or GDP (up to 1 mM) produced no relaxation of the rigor waves. Digestion with trypsin to an extent sufficient to disrupt the radial spokes and the nexin links caused no change in the rigor wave forms, suggesting that these wave forms could be maintained by the dynein cross-bridges between the outer doublet tubules of the flagellar axoneme. Study of the effects of viscous shear on the rigor wave axonemes has shown that they are resistant to distortion by bending, although they can be twisted relatively easily.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215820"} {"pmid": "4215819", "title": "Intramembrane particle aggregation in erythrocyte ghosts. I. The effects of protein removal.", "content": "Intramembrane particle aggregation in erythrocyte ghosts. I. The effects of protein removal. We have used freeze-etching and SDS-polyacrylamide gel electrophoresis to study the conditions under which the intramembrane particles of the human erythrocyte ghost may be aggregated. The fibrous membrane protein, spectrin, can be almost entirely removed from erythrocyte ghosts with little or no change in the distribution of the particles. However, after spectrin depletion, particle aggregation in the plane of the membrane may be induced by conditions which cause little aggregation in freshly prepared ghosts. This suggests that the spectrin molecules form a molecular meshwork which limits the translational mobility of the erythrocyte membrane particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215819"} {"pmid": "4215822", "title": "Lipid chromatographic determination of nitroglycerin products in waste waters.", "content": "Lipid chromatographic determination of nitroglycerin products in waste waters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215822"} {"pmid": "4215823", "title": "The extraction and recovery of chlorinated insectides and polychlorinated biphenyls from water using porous polyurethane foams.", "content": "The extraction and recovery of chlorinated insectides and polychlorinated biphenyls from water using porous polyurethane foams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215823"} {"pmid": "4215824", "title": "Biologic variation of human serum immunoglobulin concentrations: sex-age specific effects.", "content": "Biologic variation of human serum immunoglobulin concentrations: sex-age specific effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215824"} {"pmid": "4215817", "title": "Comparative experience with endocardial and epicardial pacemakers.", "content": "Comparative experience with endocardial and epicardial pacemakers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215817"} {"pmid": "4215825", "title": "The role of collagen quaternary structure in the platelet: collagen interaction.", "content": "The role of collagen quaternary structure in the platelet: collagen interaction. WE HAVE INVESTIGATED WHETHER COLLAGEN QUETERNARY STRUCTURE IS REQUIRED FOR THE PLATELET: collagen interaction. Quaternary structure refers to the assembly of collagen monomers (tropocollagen) into polymers (native-type fibrils). Purified monomeric collagen was prepared from acetic acid extracts of fetal calfskin. Polymeric collagen was prepared by dispersion of bovine Achilles tendon collagen and by incubation of monomeric collagen at 37 degrees C and pH 7.4. The state of polymerization was confirmed by electron microscopy. Release of platelet serotonin in the absence of platelet aggregation was used to determine the effectiveness of the platelet: collagen interaction. All forms of collagen produced serotonin release only after a lag period, but polymeric collagen gave a shorter lag period than did monomeric collagen. Monomeric collagen was also quanidinated selectively to convert collagen lysine groups to homoarginine, while leaving the arrangement of polar groups intact. Guanidination of monomeric collagen increased the rate of polymerization and reduced the lag time in serotonin release. Glucosamine (17 mM) retarded polymerization and inhibited the release of platelet serotonin by monomeric collagen but had little effect on release produced by thrombin or polymeric collagen. At the same concentration, glucosamine did not reduce the sensitivity of platelets to stimulation by collagen or block the platelet: collagen interaction. The only effect of glucosamine was on the collagen: collagen interaction. Galactosamine had a similar effect, but glucose, galactose, and N-acetylglycosamine had no effect. We conclude from this data that collagen monomers cannot effectively interact with platelets and that, therefore, collagen quaternary structure has a role in the recognition of collagen by platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215825"} {"pmid": "4215827", "title": "Fiber projections from trigeminal nucleus caudalis in primate (squirrel monkey and baboon).", "content": "Fiber projections from trigeminal nucleus caudalis in primate (squirrel monkey and baboon).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215827"} {"pmid": "4215829", "title": "Ordered arrangement of orientation columns in monkeys lacking visual experience.", "content": "Ordered arrangement of orientation columns in monkeys lacking visual experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215829"} {"pmid": "4215828", "title": "Efferent cortico-cortical fiber connections of area 18 in the squirrel monkey (Saimiri).", "content": "Efferent cortico-cortical fiber connections of area 18 in the squirrel monkey (Saimiri).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215828"} {"pmid": "4215831", "title": "Salmonella O antigen-coated red blood cells as a stable reagent for passive hemagglutination tests.", "content": "Salmonella O antigen-coated red blood cells as a stable reagent for passive hemagglutination tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215831"} {"pmid": "4215832", "title": "Detection of human IgA subclasses and allotypes by polymer-induced preciptation in agarose gel.", "content": "Detection of human IgA subclasses and allotypes by polymer-induced preciptation in agarose gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215832"} {"pmid": "4215826", "title": "Oral thyrotropin-releasing hormone (TRH) in depressive illness.", "content": "Oral thyrotropin-releasing hormone (TRH) in depressive illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215826"} {"pmid": "4215833", "title": "A modified 51Cr release assay for cytotoxic lymphocytes.", "content": "A modified 51Cr release assay for cytotoxic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215833"} {"pmid": "4215835", "title": "In vivo abrogation of serum C3 and C5 by administration of cobra venom factor and heterologous anti-C3.", "content": "In vivo abrogation of serum C3 and C5 by administration of cobra venom factor and heterologous anti-C3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215835"} {"pmid": "4215834", "title": "The cryopreservation of sheep erythrocyte intermediates EA nad EAC4 in complement assays.", "content": "The cryopreservation of sheep erythrocyte intermediates EA nad EAC4 in complement assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215834"} {"pmid": "4215836", "title": "Paraformaldehyde fixation in immunofluorescence and immunoelectron microscopy. Preservation of tissue and cell surface membrane antigens.", "content": "Paraformaldehyde fixation in immunofluorescence and immunoelectron microscopy. Preservation of tissue and cell surface membrane antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215836"} {"pmid": "4215838", "title": "Management of dysphagia.", "content": "Management of dysphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215838"} {"pmid": "4215837", "title": "Effects of dextrans on immunoprecipitation in agar and in low-temperature-gelling agarose gels.", "content": "Effects of dextrans on immunoprecipitation in agar and in low-temperature-gelling agarose gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215837"} {"pmid": "4215830", "title": "A third species of the owl monkey (Aotus).", "content": "A third species of the owl monkey (Aotus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215830"} {"pmid": "4215859", "title": "Electron microscopy of the trichocyst in Urostyla cristata, a hypotrichous ciliate.", "content": "Electron microscopy of the trichocyst in Urostyla cristata, a hypotrichous ciliate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215859"} {"pmid": "4215860", "title": "Observations on the effect of human chorionic gonadotrophin on the antler cycle of fallow deer.", "content": "Observations on the effect of human chorionic gonadotrophin on the antler cycle of fallow deer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215860"} {"pmid": "4215861", "title": "Melanocyte developmental genetics: biophasic control of dopa oxidase activity by the E locus of the fowl.", "content": "Melanocyte developmental genetics: biophasic control of dopa oxidase activity by the E locus of the fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215861"} {"pmid": "4215862", "title": "Microbial synthesis of folate polyglutamates from labelled precursors.", "content": "Microbial synthesis of folate polyglutamates from labelled precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215862"} {"pmid": "4215864", "title": "The biosynthesis of biotin in an auxotrophic strain of Humicola.", "content": "The biosynthesis of biotin in an auxotrophic strain of Humicola.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215864"} {"pmid": "4215863", "title": "Observations on methionine transport in Pseudomonas fluorescens UK1.", "content": "Observations on methionine transport in Pseudomonas fluorescens UK1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215863"} {"pmid": "4215865", "title": "Some properties of a bacterial protease with a specific effect on the protein in tobacco rattle virus particles.", "content": "Some properties of a bacterial protease with a specific effect on the protein in tobacco rattle virus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215865"} {"pmid": "4215866", "title": "The selective isolation of nocardia from soil using antibiotics.", "content": "The selective isolation of nocardia from soil using antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215866"} {"pmid": "4215857", "title": "Hospital-acquired infections. How they occur and what can be done to prevent them.", "content": "Hospital-acquired infections. How they occur and what can be done to prevent them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215857"} {"pmid": "4215867", "title": "Pseudomonas aeruginosa mutants defective in heptane oxidation.", "content": "Pseudomonas aeruginosa mutants defective in heptane oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215867"} {"pmid": "4215868", "title": "Fungal growth rate and the formation of ethylene in soil.", "content": "Fungal growth rate and the formation of ethylene in soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215868"} {"pmid": "4215869", "title": "Three previously undescribed viruses from the honey bee.", "content": "Three previously undescribed viruses from the honey bee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215869"} {"pmid": "4215871", "title": "Axonal growth and organization of the mamillary nuclei of the newborn mouse in culture.", "content": "Axonal growth and organization of the mamillary nuclei of the newborn mouse in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215871"} {"pmid": "4215858", "title": "A comparative study: health care delivery in New Jersey county, state, Federal, and private mental hospitals.", "content": "A comparative study: health care delivery in New Jersey county, state, Federal, and private mental hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215858"} {"pmid": "4215872", "title": "Responses to tonal stimuli of single auditory nerve fibers and their relationship to basilar membrane motion in the squirrel monkey.", "content": "Responses to tonal stimuli of single auditory nerve fibers and their relationship to basilar membrane motion in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215872"} {"pmid": "4215870", "title": "Distribution of acetylcholine, choline, choline acetyltransferase and acetylcholinesterase in regions and single identified axons of the lobster nervous system.", "content": "Distribution of acetylcholine, choline, choline acetyltransferase and acetylcholinesterase in regions and single identified axons of the lobster nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215870"} {"pmid": "4215873", "title": "Studies on the metabolic interrelationship between biotin and folic acid in rats.", "content": "Studies on the metabolic interrelationship between biotin and folic acid in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215873"} {"pmid": "4215875", "title": "Immunopathological studies on cryoimmunisation of the rabbit male accessory glands.", "content": "Immunopathological studies on cryoimmunisation of the rabbit male accessory glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215875"} {"pmid": "4215876", "title": "Dipetalonema barbascalensis sp. n. (Nematoda:Filarioidea) from the owl monkey, Aotus trivirgatus, with a consideration of the status of Parlitomosa zakii Nagaty, 1935.", "content": "Dipetalonema barbascalensis sp. n. (Nematoda:Filarioidea) from the owl monkey, Aotus trivirgatus, with a consideration of the status of Parlitomosa zakii Nagaty, 1935.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215876"} {"pmid": "4215877", "title": "Isolation of Trypanosoma cruzi from blood.", "content": "Isolation of Trypanosoma cruzi from blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215877"} {"pmid": "4215878", "title": "Relationship between periodontal injury, selective cell repopulation and ankylosis.", "content": "Relationship between periodontal injury, selective cell repopulation and ankylosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215878"} {"pmid": "4215879", "title": "Further studies on the role of prostaglandin in fever.", "content": "Further studies on the role of prostaglandin in fever. 1. Experiments were carried out in unanaesthetized cats to find out if a prostaglandin is the mediator (a) for the long lasting fever which often follows injections of phsyiological salt solutions into the cerebral ventricles or into the cisterna magna, as well as their perfusions through the cerebral ventricles, and (b) for the sodium fever which occurs during a perfusion of the cerebral ventricles with calcium-free artificial c.s.f. A fever mediated by prostaglandin should be accompanied by an increase of prostaglandin activity in cisternal c.s.f., and be abolished or prevented by antipyretics like paracetamol or indomethacin which inhibit prostaglandin synthesis. Both criteria were applied.2. The fever which follows injections or perfusions of physiological salt solutions appears to be mediated by a prostaglandin of the E series, probably E(2) (PGE(2)) because it was accompanied by increased prostaglandin E-like activity in the c.s.f. and abolished by paracetamol and indomethacin. During the first few days after pre-treatment of the cats with intramuscular chloramphenicol the injections were rarely followed by fever.3. The fever which occurs during a perfusion with calcium-free artificial c.s.f. appears not to be mediated by prostaglandin, because it was not associated with increased prostaglandin activity in the cisternal effluent, and not prevented by paracetamol or indomethacin, although these antipyretics usually attenuated the fever.4. A perfusion of the cerebral ventricles with artificial c.s.f. containing calcium in an abnormally high concentration (6.25 mM) brought down fever produced by PGE(1), or PGE(2), or bacterial pyrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215879"} {"pmid": "4215880", "title": "Role of cations, anions and carbonic anhydrase in fluid transport across rabbit corneal endothelium.", "content": "Role of cations, anions and carbonic anhydrase in fluid transport across rabbit corneal endothelium. 1. A small electrical potential difference (541 +/- 48 muV, aqueous side negative) across rabbit corneal endothelium has been recently found. Its dependence on ambient [Na(+)], [K(+)], [H(+)] and metabolic and specific inhibitors was examined.2. Changes in concentration of the ions above either were known or were presently shown to affect the rate of fluid transport across this preparation (normal value: 5.2 +/- 0.4 mul./hr.cm(2)). Ionic concentration changes were also found here to influence potential difference in the same way as fluid transport. In the cases tested, the effects on both fluid transport and potential difference were reversible.3. Fluid transport and potential difference were both decreased or abolished in absence of Na(+), K(+) and HCO(3) (-), and when [H(+)] was decreased. Fluid transport and potential difference were saturable functions of [HCO(3) (-)] and half-saturation occurred in both cases at about 13 mM-HCO(3) (-). The potential difference was also a saturable function of [Na(+)] (half-saturation around 15 mM). There was a pH optimum for potential difference in the range 7.4-7.6. Lower pH values decreases the potential difference and the fluid transport, and a small (-100 muV) reversed potential was observed in the range of 5.3-5.5.4. Total replacement of Cl(-) by HCO(3) (-) or SO(4) (2-) produced no impairment on either fluid transport or potential difference.5. Carbonic anhydrase inhibitors (ethoxyzolamide 10(-5) or 10(-4)M and benzolamide 10(-3)M) produced a 40-60% decrease in the rate of fluid pumping. In contrast, ethoxyzolamide 10(-4)M or acetazolamide 10(-3)M did not produce any change in the potential difference. NaCN and Na iodoacetate (both 2 mM) eliminated the potential difference in 1-1.5 hr while in controls it lasted for 5-6 hr.6. Ouabain (10(-5)M) abolished the potential difference in less than 10 sec when added to the aqueous side, which suggests the existence of an electrogenic pump. This extremely fast time transient can be accounted for by the accessibility and simple geometry of the present monocellular layer. Ouabain abolished also the reversed potential difference observed at low pH.7. The data are interpreted in terms of a scheme similar to that advanced for other epithelia and in which (a) H(+) would be pumped into the intercellular spaces, while Na(+) and CO(2) would enter into the cells, and (b) Na(+) would be subsequently pumped into the aqueous humour, producing as a result the fluid movement observed. The actual origin of the potential difference is further discussed in terms of two contrasting possibilities: (i) one or more electrogenic pumps, and (ii) a neutral pump which would create a diffusion potential across ;leaky' intercellular junctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215880"} {"pmid": "4215883", "title": "Effect of oral contraceptives on body water and electrolytes.", "content": "Effect of oral contraceptives on body water and electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215883"} {"pmid": "4215885", "title": "Thermoelectric freeze-drying.", "content": "Thermoelectric freeze-drying.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215885"} {"pmid": "4215884", "title": "Freeze-substitution: a method for the rapid arrest and chemical fixation of spermatozoa.", "content": "Freeze-substitution: a method for the rapid arrest and chemical fixation of spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215884"} {"pmid": "4215886", "title": "Third National Cancer Survey--an overview of available information.", "content": "Third National Cancer Survey--an overview of available information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215886"} {"pmid": "4215887", "title": "An antigen-binding cell tumor: heterophile cold hemagglutinin as a membrane-bound receptor on a mouse lymphoma.", "content": "An antigen-binding cell tumor: heterophile cold hemagglutinin as a membrane-bound receptor on a mouse lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215887"} {"pmid": "4215888", "title": "The arm/head ratio in the assessment of protein-calorie malnutrition in Baghdad.", "content": "The arm/head ratio in the assessment of protein-calorie malnutrition in Baghdad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215888"} {"pmid": "4215889", "title": "The significance of perineal pathogens in women.", "content": "The significance of perineal pathogens in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215889"} {"pmid": "4215890", "title": "Fungal nephritis in a grey-headed albatross.", "content": "Fungal nephritis in a grey-headed albatross.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215890"} {"pmid": "4215891", "title": "Case reports of ossifying fibromata in the striped mullet.", "content": "Case reports of ossifying fibromata in the striped mullet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215891"} {"pmid": "4215892", "title": "Opercular cyst formation in trout infected with Myxosoma cerebralis.", "content": "Opercular cyst formation in trout infected with Myxosoma cerebralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215892"} {"pmid": "4215893", "title": "Simulated field blood studies in the bottle-nosed dolphin Tursiops truncatus. 3. Changes in hematology and chemistry during blood and plasma storage.", "content": "Simulated field blood studies in the bottle-nosed dolphin Tursiops truncatus. 3. Changes in hematology and chemistry during blood and plasma storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215893"} {"pmid": "4215894", "title": "Hematozoa of the Anatidae of the Atlantic flyway. 1. Massachusetts.", "content": "Hematozoa of the Anatidae of the Atlantic flyway. 1. Massachusetts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215894"} {"pmid": "4215895", "title": "Avian hematozoa of some Ugandan birds.", "content": "Avian hematozoa of some Ugandan birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215895"} {"pmid": "4215905", "title": "Antigenicity of bicyclomycin and its cross-reactivity with benzylpenicillin.", "content": "Antigenicity of bicyclomycin and its cross-reactivity with benzylpenicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215905"} {"pmid": "4215912", "title": "Skin reaction produced by endotoxins and lactobacillus in mouse.", "content": "Skin reaction produced by endotoxins and lactobacillus in mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215912"} {"pmid": "4215913", "title": "Preparation and characterization of the monospecific antiserum directed to the ninth component of human complement (C9).", "content": "Preparation and characterization of the monospecific antiserum directed to the ninth component of human complement (C9).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215913"} {"pmid": "4215914", "title": "Corneal ulcers caused by protease and elastase from Pseudomonas aeruginosa.", "content": "Corneal ulcers caused by protease and elastase from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215914"} {"pmid": "4215915", "title": "Letter: Elevation of serum C9 level associated with Behçet disease.", "content": "Letter: Elevation of serum C9 level associated with Behçet disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215915"} {"pmid": "4215917", "title": "Studies on methods for evaluation of anticoccidial drugs in vitro.", "content": "Studies on methods for evaluation of anticoccidial drugs in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215917"} {"pmid": "4215918", "title": "Yersinia pseudotuberculosis infection occurred spontaneously in a group of patas monkeys (Erythrocebus patas).", "content": "Yersinia pseudotuberculosis infection occurred spontaneously in a group of patas monkeys (Erythrocebus patas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215918"} {"pmid": "4215919", "title": "Experimental studies on glucuronidation. III. UDP-glucuronyltransferase activity and glucuronide excretion enhanced by oral administration of eugenol.", "content": "Experimental studies on glucuronidation. III. UDP-glucuronyltransferase activity and glucuronide excretion enhanced by oral administration of eugenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215919"} {"pmid": "4215925", "title": "A scanning electron microscopic study of gallstone development in man.", "content": "A scanning electron microscopic study of gallstone development in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215925"} {"pmid": "4215924", "title": "The osteochondral junction of mammalian joints. An ultrastructural and microanalytic study.", "content": "The osteochondral junction of mammalian joints. An ultrastructural and microanalytic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215924"} {"pmid": "4215927", "title": "Positional information in unicellular organisms.", "content": "Positional information in unicellular organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215927"} {"pmid": "4215926", "title": "Dietary fibre in human nutrition.", "content": "Dietary fibre in human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215926"} {"pmid": "4215933", "title": "Properties of palmityl-CoA: L-alpha-glycerolphosphate acyl transferase from bovine mammary microsomes.", "content": "Properties of palmityl-CoA: L-alpha-glycerolphosphate acyl transferase from bovine mammary microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215933"} {"pmid": "4215928", "title": "Aging and long-term temporal regulation in ciliated protozoa. A critical review.", "content": "Aging and long-term temporal regulation in ciliated protozoa. A critical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215928"} {"pmid": "4215938", "title": "Biphasic adrenergic responses of rabbit aorta.", "content": "Biphasic adrenergic responses of rabbit aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215938"} {"pmid": "4215937", "title": "Brucellosis in the United States, 1960-1972. An abattoir-associated disease. Part I. Clinical features and therapy.", "content": "Brucellosis in the United States, 1960-1972. An abattoir-associated disease. Part I. Clinical features and therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215937"} {"pmid": "4215939", "title": "Absorption and excretion of amoxycillin and pivampicillin, two new semisynthetic penicillins.", "content": "Absorption and excretion of amoxycillin and pivampicillin, two new semisynthetic penicillins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215939"} {"pmid": "4215940", "title": "Letter: Psychosis associated with sympathomimetic and cromoglycate therapy.", "content": "Letter: Psychosis associated with sympathomimetic and cromoglycate therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215940"} {"pmid": "4215941", "title": "Usefulness of rheophoresis for detection of Australia antigen.", "content": "Usefulness of rheophoresis for detection of Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215941"} {"pmid": "4215944", "title": "Multiple loop inoculator as an aid in bacteriocine typing techniques.", "content": "Multiple loop inoculator as an aid in bacteriocine typing techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215944"} {"pmid": "4215945", "title": "A comparative study of the fluorescent treponemal antibody-absorbed test and some existing methods available for the serological diagnosis of syphilis.", "content": "A comparative study of the fluorescent treponemal antibody-absorbed test and some existing methods available for the serological diagnosis of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215945"} {"pmid": "4215950", "title": "Clinical parameters of high energy linear accelerators.", "content": "Clinical parameters of high energy linear accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215950"} {"pmid": "4215951", "title": "Restriction and modification in B. subtilis. Biological aspects.", "content": "Restriction and modification in B. subtilis. Biological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215951"} {"pmid": "4215952", "title": "Host controlled modification and restriction in Bacillus subtilis.", "content": "Host controlled modification and restriction in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215952"} {"pmid": "4215954", "title": "Relationship between the nature of the nucleotide sequence and the degree of asymmetry of the complementary strands of DNA in microorganisms.", "content": "Relationship between the nature of the nucleotide sequence and the degree of asymmetry of the complementary strands of DNA in microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215954"} {"pmid": "4215953", "title": "Mature DNA from temperate bacillusphage phi105 requires primary recombination to be infectious in transfection.", "content": "Mature DNA from temperate bacillusphage phi105 requires primary recombination to be infectious in transfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215953"} {"pmid": "4215946", "title": "Calculations pertaining to the use of fast (equal to or less than 50-MeV) neutrons in cancer radiotherapy.", "content": "Calculations pertaining to the use of fast (equal to or less than 50-MeV) neutrons in cancer radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215946"} {"pmid": "4215955", "title": "Matrix activity of the X chromosomes of male and female drosophilas in the synthesis of RNA by bacterial RNA-polymerase.", "content": "Matrix activity of the X chromosomes of male and female drosophilas in the synthesis of RNA by bacterial RNA-polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215955"} {"pmid": "4215948", "title": "Measurements of electron-beam energy with rapid-processed film.", "content": "Measurements of electron-beam energy with rapid-processed film.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215948"} {"pmid": "4215949", "title": "Downtime experience for clinical linear accelerators.", "content": "Downtime experience for clinical linear accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215949"} {"pmid": "4215947", "title": "Experimental and calculated bremsstrahlung spectra from a 25-MeV linear accelerator and a 19-MeV betatron.", "content": "Experimental and calculated bremsstrahlung spectra from a 25-MeV linear accelerator and a 19-MeV betatron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215947"} {"pmid": "4215970", "title": "Investigations on radiosensitive and radioresistant populations of Drosophila melanogaster. V. Relations between the relative radioresistance and some recombination properties in the irradiated population ROI.", "content": "Investigations on radiosensitive and radioresistant populations of Drosophila melanogaster. V. Relations between the relative radioresistance and some recombination properties in the irradiated population ROI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215970"} {"pmid": "4215971", "title": "The induction of temperature-sensitive mutations in Drosophila melanogaster by the acridine mustard ICR-170.", "content": "The induction of temperature-sensitive mutations in Drosophila melanogaster by the acridine mustard ICR-170.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215971"} {"pmid": "4215972", "title": "Endotoxic substance of Cryptococcus neoformans.", "content": "Endotoxic substance of Cryptococcus neoformans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215972"} {"pmid": "4215973", "title": "Clinical evaluation of antibody sensitized latex particles method for Australia antigen in serum.", "content": "Clinical evaluation of antibody sensitized latex particles method for Australia antigen in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215973"} {"pmid": "4215974", "title": "Detoxification of long-term methadone patients.", "content": "Detoxification of long-term methadone patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215974"} {"pmid": "4215975", "title": "Myth versus fact in long term methadone maintenance treatment: the community's viewpoint.", "content": "Myth versus fact in long term methadone maintenance treatment: the community's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215975"} {"pmid": "4215976", "title": "Significance of hypermacroglobulinemia in methadone maintained and other narcotic addicts.", "content": "Significance of hypermacroglobulinemia in methadone maintained and other narcotic addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215976"} {"pmid": "4215977", "title": "New choices for methadone maintenance patients: planned, voluntary long-term detoxification.", "content": "New choices for methadone maintenance patients: planned, voluntary long-term detoxification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215977"} {"pmid": "4215979", "title": "Identification of metabolic dechlorination of highly chlorinated biphenyl in rabbit.", "content": "Identification of metabolic dechlorination of highly chlorinated biphenyl in rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215979"} {"pmid": "4215978", "title": "Methadone and naloxone in combination (Naldone) for the treatment of heroin addicts.", "content": "Methadone and naloxone in combination (Naldone) for the treatment of heroin addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215978"} {"pmid": "4215980", "title": "Beta alanine and cuticle maturation in Drosophila.", "content": "Beta alanine and cuticle maturation in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215980"} {"pmid": "4215981", "title": "Purification and properties of protease produced by Staphylococcus aureus strain SH-91 isolated from diseased chickens.", "content": "Purification and properties of protease produced by Staphylococcus aureus strain SH-91 isolated from diseased chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215981"} {"pmid": "4215986", "title": "Ovulation induced by norepinephrine in rats made anovulatory by various experimental procedures.", "content": "Ovulation induced by norepinephrine in rats made anovulatory by various experimental procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215986"} {"pmid": "4215987", "title": "Response variables and motor slow cortical potentials (SCP) during performance of learned movements in the squirrel monkey (Saimiri sciureus).", "content": "Response variables and motor slow cortical potentials (SCP) during performance of learned movements in the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215987"} {"pmid": "4215992", "title": "Correlation conferences in radiology and pathology: osseous lesions in adolescence with known neurofibromatosis.", "content": "Correlation conferences in radiology and pathology: osseous lesions in adolescence with known neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215992"} {"pmid": "4215993", "title": "Value of HCS determinations in management of prolonged pregnancy.", "content": "Value of HCS determinations in management of prolonged pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215993"} {"pmid": "4215995", "title": "Lactobacilli of infected dental root canals.", "content": "Lactobacilli of infected dental root canals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215995"} {"pmid": "4215994", "title": "In vitro studies of human ovarian contractility.", "content": "In vitro studies of human ovarian contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215994"} {"pmid": "4215997", "title": "Chronic secretory otitis media--long-term results after treatment with grommets.", "content": "Chronic secretory otitis media--long-term results after treatment with grommets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215997"} {"pmid": "4215996", "title": "Spontaneous tumours in amphibia. A review.", "content": "Spontaneous tumours in amphibia. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4215996"} {"pmid": "4216002", "title": "DDT plus PCB'S in blubber of harbor seals.", "content": "DDT plus PCB'S in blubber of harbor seals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216002"} {"pmid": "4216003", "title": "Chlorinated hydrocarbon and mercury residues in wookcock in the United States, 1970-71.", "content": "Chlorinated hydrocarbon and mercury residues in wookcock in the United States, 1970-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216003"} {"pmid": "4216004", "title": "Selected chlorinated hydrocarbons in bottom material from streams tributary to San Francisco Bay.", "content": "Selected chlorinated hydrocarbons in bottom material from streams tributary to San Francisco Bay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216004"} {"pmid": "4216005", "title": "Organochlorine residues in golden eagles, United States--March 1964-July 1971.", "content": "Organochlorine residues in golden eagles, United States--March 1964-July 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216005"} {"pmid": "4216006", "title": "Experimentally induced periapical inflammation in permanent and primary teeth of monkeys.", "content": "Experimentally induced periapical inflammation in permanent and primary teeth of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216006"} {"pmid": "4216007", "title": "Prolonging life by mechanical means--the role of the nurse.", "content": "Prolonging life by mechanical means--the role of the nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216007"} {"pmid": "4216008", "title": "Socio-economic disease.", "content": "Socio-economic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216008"} {"pmid": "4216009", "title": "Editorial: Longstay problems.", "content": "Editorial: Longstay problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216009"} {"pmid": "4216010", "title": "Tuberculosis in Africans. Prolonged observations on drug sensitivity of M. tuberculosis during chemotherapy.", "content": "Tuberculosis in Africans. Prolonged observations on drug sensitivity of M. tuberculosis during chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216010"} {"pmid": "4216016", "title": "Prevention and future control of hospital-associated infections commonly caused by gram-negative bacteria.", "content": "Prevention and future control of hospital-associated infections commonly caused by gram-negative bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216016"} {"pmid": "4216017", "title": "An inhibitor of cell proliferation released by cultures of macrophages.", "content": "An inhibitor of cell proliferation released by cultures of macrophages. Culture fluids from mouse peritoneal exudate cells inhibited [(3)H]thymidine incorporation by, and proliferation of, EL-4 leukemia cells, 3T3 cells, and mitogen-stimulated spleen lymphocytes. Inhibited EL-4 leukemia cells recovered their normal proliferative capacity when washed and incubated in normal medium. The inhibitory activity resided in a low-molecular-weight substance that could be absorbed by incubation with the tumor cells. This substance was dialyzable and resistant to tryptic digestion and phosphodiesterase treatment. The mononuclear phagocytes in the peritoneal exudate seemed to be the source of the inhibitor. The inhibitory material was found in the same amounts in exudates of normal mice or mice injected with peptone or infected with Listeria monocytogenes; spleen cells adherent to plastic released the inhibitor but in lesser amount. We suggest that this inhibitor may contribute to the deleterious effects found when various cells, including neoplastic ones, are cultured in the presence of macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216017"} {"pmid": "4216018", "title": "Pyrrole hydrogen ionization of imidazole derivatives in metal ion complexes and carbonic anhydrase.", "content": "Pyrrole hydrogen ionization of imidazole derivatives in metal ion complexes and carbonic anhydrase. Zinc ion-induced pyrrole hydrogen ionization from a histidyl residue has recently been suggested as the source of the activity-related deprotonation in carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase) occurring at pH 7-8. The results offered to support the hypothesis are shown to be deficient. Examination of the literature reveals no precedent for such a pronounced acidification from pK(a) [unk] 14.2 in imidazole compounds by zinc ion. It is suggested that Zn(II)-induced pyrrole ionizations in imidazoles occur with pK(a) about 13.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216018"} {"pmid": "4216019", "title": "Viable molecular hybrids of bacteriophage lambda and eukaryotic DNA.", "content": "Viable molecular hybrids of bacteriophage lambda and eukaryotic DNA. A bacteriophage lambda strain has been constructed and a method developed by which DNA from potentially any source can be covalently inserted through EcoRI cohesive ends into the middle of the lambda DNA. These hybrid DNAs can infect nonrestricting Escherichia coli cells and can then propagate as plaque-forming phage. A unique feature of this lambda strain is that extra DNA in the middle of its genome is required for plaque formation. A large number of such phages have been produced with E. coli DNA and Drosophila melanogaster DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216019"} {"pmid": "4216020", "title": "Restriction endonuclease cleavage maps of animal mitochondrial DNAs.", "content": "Restriction endonuclease cleavage maps of animal mitochondrial DNAs. The restriction endonuclease, HindIII, gives rise to three fragments in each of the three mitochondrial DNAs isolated from the established mammalian cell lines LA9 (mouse), HeLa (human), and BSC-1 (African green monkey). The restriction endonuclease, EcoRI, gives rise to three fragments in mitochondrial DNA from HeLa and to two in DNAs from LA9 and BSC-1. The sizes and the orders of the fragments in the respective genomes have been determined with data obtained from the electron microscope. The origin and the direction of replication have been designated in each of the cleavage maps. Polyacrylamide gel electrophoretic analyses demonstrated that additional fragments not detectable in the electron microscope and larger than 50 nucleotide pairs were not present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216020"} {"pmid": "4216022", "title": "Preparation and spectroscopic studies of cobalt(II) derivatives of blue copper proteins.", "content": "Preparation and spectroscopic studies of cobalt(II) derivatives of blue copper proteins. Preparation of cobalt(II) derivatives of type 1 copper proteins has been extended to include bean plastocyanin and azurin from Pseudomonas aeruginosa. Fluorescence quenching data suggest that Co(II) binds to the type 1 site of both apoplastocyanin and apoazurin. Electronic absorption spectral measurements have been made for cobalt(II)-stellacyanin, cobalt(II)-plastocyanin, and cobalt(II)-azurin. In each case two visible bands with moderate intensities and two rather strong ultraviolet absorption peaks are observed. The intensity pattern and the separation of the two ultraviolet bands in the Co(II) derivatives correspond closely to the two intense, low-lying absorption peaks in the analogous, type 1 copper proteins. The evidence suggests that the intense, two-band systems represent ligand-to-metal charge transfer transitions in both Cu(II) and Co(II) derivatives. It is proposed that the transitions in each case originate in the 3ppi and 3psigma orbitals of a cysteine sulfur ligand at the type 1 site. The visible absorption bands in the Co(II) derivatives are assigned to d-d transitions. The large (4)P splitting observed indicates that the type 1 Co(II) site is of low symmetry. The d-d band pattern suggests that the high-spin Co(II) center is either distorted tetrahedral or five-coordinate. The observed band intensities are in much closer accord with the values for Co(II) complexes known to have distorted tetrahedral structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216022"} {"pmid": "4216021", "title": "Fluorescence enhancement of laccase induced by reduction of Cu(II) sites.", "content": "Fluorescence enhancement of laccase induced by reduction of Cu(II) sites. The intrinsic fluorescence of laccase (p-diphenol:O(2) oxidoreductase, EC 1.10.3.2), emitted by its tyrosinyl and tryptophanyl residues, underwent significant enhancement upon reduction of the enzyme redox sites. The increase in quantum yield reached its maximum after the addition of approximately four reduction equivalents and depended on the wavelength of excitation:54% increase for lambda(ex) = 250 nm and 76% for lambda(ex) = 305 nm.A linear correlation between this enhancement and the reduction of the type 1 Cu(II) was observed both by direct measurement and by calculation on the basis of added reductant. The implications of the fluorescence enhancement and its correlation with the reduction of the type 1 copper are discussed in terms of the possible quenching mechanisms. The possibility of a redox-induced structural transition in the protein is suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216021"} {"pmid": "4216023", "title": "Isolation of DNA-membrane complex in Bacillus subtilis.", "content": "Isolation of DNA-membrane complex in Bacillus subtilis. A DNA-membrane complex of Bacillus subtilis was separated from the bulk of the membrane by CsCl-sucrose double gradient centrifugation. The complex has a CsCl-sucrose buoyant density of 1.35-1.45 g/cm(3). Gel electrophoretic analyses show that the complex has about 5% of the whole membrane proteins and contains proteins unique to the complex as well as a small amount of membrane proteins. DNA in the complex is enriched for a genetic marker close to the origin (pur A16) and for one near the terminus (metB5). Artifactual formation of the complex during the lysate preparation was shown to be unlikely.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216023"} {"pmid": "4216025", "title": "The effects of increased temperature on electroretinograms of temperature-sensitive paralysis mutants of Drosophila melanogaster.", "content": "The effects of increased temperature on electroretinograms of temperature-sensitive paralysis mutants of Drosophila melanogaster. Mutations within the shibire locus of Drosophila melanogaster are non-complementing alleles which result in reversible paralysis at 29 degrees but retention of normal locomotor behavior at 22 degrees . Electroretinograms of six of the mutants have been recorded at various temperatures. Two changes occurred in the electroretinograms of flies carrying most of the alleles at high temperature: they lost the \"on\"- and \"off\"- transients of the normal electroretinogram, and the fast decay of the receptor potential was attenuated. For flies with four of the alleles, a base-line oscillation was also observed. Analysis of electroretinograms of mosaic shibire flies indicates that the loss of the transients can be attributed to both a pre-synaptic and a post-synaptic effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216025"} {"pmid": "4216024", "title": "Chloramphenicol restores sigma factor activity to sporulating Bacillus subtilis.", "content": "Chloramphenicol restores sigma factor activity to sporulating Bacillus subtilis. The sigma subunit of RNA polymerase from sporulating Bacillus subtilis is markedly inhibited in its ability to direct active transcription of phage varphie DNA in vitro. Treatment of sporulating bacteria with chloramphenicol rapidly restores sigma activity, suggesting that sporulating cells contain an inhibitor of sigma that is physiologically unstable or that becomes unstable after drug treatment. The hypothetical inhibitor is depleted exponentially with an apparent half-life of 11 min at 37 degrees .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216024"} {"pmid": "4216026", "title": "Sequence homology between the RNA of Mason-Pfizer monkey virus and the RNA of human malignant breast tumors.", "content": "Sequence homology between the RNA of Mason-Pfizer monkey virus and the RNA of human malignant breast tumors. Radioactive DNA ([(3)H]cDNA) complementary to the RNA of Mason-Pfizer monkey virus was used in molecular hybridization experiments to demonstrate sequence homology between its viral RNA and RNA of human malignant breast tumors. Hybridization products were analyzed by cesium sulfate equilibrium density centrifugation and hydroxylapatite chromatography. Seven of ten human malignant breast tumors tested contained virus-related RNA when assayed by hydroxylapatite chromatography, whereas no sequence homology was found in RNA from 11 human benign breast tumors or from RNA of normal human spleen, liver, or kidney. Hybridizations between [(3)H]cDNA of the monkey virus and human breast adenocarcinoma RNA showed a C(r)t((1/2)) of about 2 x 10(4). The fidelity of the hybrids formed was indicated by a T(m) of 80.5 degrees .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216026"} {"pmid": "4216027", "title": "Kinetic constants determined from membrane transport measurements: carbonic anhydrase activity at high concentrations.", "content": "Kinetic constants determined from membrane transport measurements: carbonic anhydrase activity at high concentrations. Facilitated diffusion rates can be used to determine kinetic constants for rapid reactions occurring within membranes and thin fluid layers. We have applied this technique to the study of the reversible CO(2) hydration reactions catalyzed by carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase). The experimental method entails the diffusion of tracer (14)CO(2) through Millipore filter membranes impregnated with aqueous bicarbonate solutions containing various concentrations of dissolved enzyme. A mathematical model of the simultaneous diffusion/reaction transport process is analyzed to predict the effective diffusion rate in terms of the relevant kinetic parameters. The solution to the mathematical model can be transformed to yield straight-line relations analogous to Lineweaver-Burk plots. The pseudo-first-order enzymatic rate constant for the hydration reaction can be determined from the slope or intercept of a plot of this straight-line relationship. Rate constants were accurately measured at high enzyme concentrations for reactions having half-times under a millisecond. The rate constants agree well with other reported kinetic constants for carbonic anhydrase, and the known pH-activity dependence and bicarbonate inhibition are quantitatively demonstrated. The specific activity is constant up to 4.0 mg/ml, which is believed to be the highest concentration at which the activity has been measured. The membrane transport technique has general applicability for other rapid reaction systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216027"} {"pmid": "4216028", "title": "Differentiation of lens-like structures from newt iris epithelial cells in vitro.", "content": "Differentiation of lens-like structures from newt iris epithelial cells in vitro. Dissociated cells of pigmented iris epithelium from adult newts grew intensively in monolayer cultures after a lag of two to three weeks. During the lag period, depigmentation occurred in many cells. When cultures became confluent five to six weeks after seeding, many tiny lens-like structures (30-70 per plate) differentiated from dense foci of amelanotic epithelial cells. These lens-like structures appeared in all cultures originated from cells of ventral as well as dorsal iris. The identification of these structures as lens was established by both immunological and ultrastructural techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216028"} {"pmid": "4216029", "title": "Abnormal solubilization by triton X-100 of erythrocyte membranes from patients with paroxysmal nocturnal hemoglobinuria.", "content": "Abnormal solubilization by triton X-100 of erythrocyte membranes from patients with paroxysmal nocturnal hemoglobinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216029"} {"pmid": "4216030", "title": "Electrophoretic evaluation of various procedures for solubilizing erythrocyte membranes.", "content": "Electrophoretic evaluation of various procedures for solubilizing erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216030"} {"pmid": "4216031", "title": "Cholesterol absorption in primates as determined by the Zilversmit isotope ratio method.", "content": "Cholesterol absorption in primates as determined by the Zilversmit isotope ratio method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216031"} {"pmid": "4216032", "title": "Immunological studies of thrombopoietin.", "content": "Immunological studies of thrombopoietin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216032"} {"pmid": "4216033", "title": "Fletcher factor activity in plasmas of various species.", "content": "Fletcher factor activity in plasmas of various species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216033"} {"pmid": "4216035", "title": "Immune and nonimmune gel precipitates produced by honey bee venom and its components.", "content": "Immune and nonimmune gel precipitates produced by honey bee venom and its components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216035"} {"pmid": "4216034", "title": "The synthesis of taurine from sulfate. VIII. A constitutive enzyme in mammals.", "content": "The synthesis of taurine from sulfate. VIII. A constitutive enzyme in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216034"} {"pmid": "4216036", "title": "Standardized production in goats of antilymphocyte globulin and its clinical use.", "content": "Standardized production in goats of antilymphocyte globulin and its clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216036"} {"pmid": "4216038", "title": "Discrimination learning differences and similarities as a function of brain index.", "content": "Discrimination learning differences and similarities as a function of brain index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216038"} {"pmid": "4216039", "title": "Perceptual generalization: a note on the peak shift.", "content": "Perceptual generalization: a note on the peak shift.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216039"} {"pmid": "4216041", "title": "Immunologic considerations of carcinoma of the prostate.", "content": "Immunologic considerations of carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216041"} {"pmid": "4216042", "title": "Significance of paraproteins in neoplastic disease.", "content": "Significance of paraproteins in neoplastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216042"} {"pmid": "4216044", "title": "Biological effects of gravitational fields.", "content": "Biological effects of gravitational fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216044"} {"pmid": "4216043", "title": "Biological effects during space flights.", "content": "Biological effects during space flights.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216043"} {"pmid": "4216054", "title": "Perceptual learning ability in Mandrillus sphinx and Cercopithecus nictitans.", "content": "Perceptual learning ability in Mandrillus sphinx and Cercopithecus nictitans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216054"} {"pmid": "4216055", "title": "Glycogen synthetase activity in the sea mussel (Mytilus edulis, l.).", "content": "Glycogen synthetase activity in the sea mussel (Mytilus edulis, l.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216055"} {"pmid": "4216057", "title": "O-diphenol:oxygen-oxidoreductase from Musa cavendishii.", "content": "O-diphenol:oxygen-oxidoreductase from Musa cavendishii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216057"} {"pmid": "4216056", "title": "Purification of frog muscle glycogen synthetase.", "content": "Purification of frog muscle glycogen synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216056"} {"pmid": "4216059", "title": "Cannabinol-7-oic acid: a metabolite of delta1-tetrahydrocannabinol in the rhesus monkey.", "content": "Cannabinol-7-oic acid: a metabolite of delta1-tetrahydrocannabinol in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216059"} {"pmid": "4216058", "title": "Blood flow metabolism couple in brain.", "content": "Blood flow metabolism couple in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216058"} {"pmid": "4216060", "title": "The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rat.", "content": "The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216060"} {"pmid": "4216061", "title": "Increased half-life of rat liver RNA following dietary administration of 3'-methyl-4-dimethylaminoazobenzene and/or chloramphenicol.", "content": "Increased half-life of rat liver RNA following dietary administration of 3'-methyl-4-dimethylaminoazobenzene and/or chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216061"} {"pmid": "4216072", "title": "The coordination of eye-head movements.", "content": "The coordination of eye-head movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216072"} {"pmid": "4216073", "title": "Aerial dispersal of micro-organisms from the human respiratory tract.", "content": "Aerial dispersal of micro-organisms from the human respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216073"} {"pmid": "4216074", "title": "Effects of soaps, germicides and disinfectants on the skin flora.", "content": "Effects of soaps, germicides and disinfectants on the skin flora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216074"} {"pmid": "4216075", "title": "Arrhinencephaly in aberrations of autosomal chromosomes and sequential chromosomal functional expression.", "content": "Arrhinencephaly in aberrations of autosomal chromosomes and sequential chromosomal functional expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216075"} {"pmid": "4216076", "title": "Effect of mutagens on MS2 phage and its infectious RNA. Communication III. Action of o-methylhydroxylamine and analysis of inactivation kinetics.", "content": "Effect of mutagens on MS2 phage and its infectious RNA. Communication III. Action of o-methylhydroxylamine and analysis of inactivation kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216076"} {"pmid": "4216077", "title": "Experiments on the antimutagenic effect of AET (beta-aminoethylisothiuronium bromide) in Drosophila melanogaster.", "content": "Experiments on the antimutagenic effect of AET (beta-aminoethylisothiuronium bromide) in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216077"} {"pmid": "4216078", "title": "Nonhomologous chromosome pairing in oogenesis of XXY females of Drosophila melanogaster. Communication I. Nonhomologous pairing X-Y, X-2, Y-2, in XXY females; Cy-Xa.", "content": "Nonhomologous chromosome pairing in oogenesis of XXY females of Drosophila melanogaster. Communication I. Nonhomologous pairing X-Y, X-2, Y-2, in XXY females; Cy-Xa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216078"} {"pmid": "4216079", "title": "Intensity of chemical mutagenesis in human cells as a function of age and sex.", "content": "Intensity of chemical mutagenesis in human cells as a function of age and sex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216079"} {"pmid": "4216080", "title": "Study of the rate of development of Drosophila heterozygous with respect to radio-induced mutations.", "content": "Study of the rate of development of Drosophila heterozygous with respect to radio-induced mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216080"} {"pmid": "4216081", "title": "A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication III. Influence of temperature on the penetrance and expressivity of the Apx and Ns genes.", "content": "A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication III. Influence of temperature on the penetrance and expressivity of the Apx and Ns genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216081"} {"pmid": "4216082", "title": "Effect of mutagens on MS2 phage and its infectious RNA. Communication IV. Effect of O-methylhydroxylamine. Analysis of mutagenesis kinetics.", "content": "Effect of mutagens on MS2 phage and its infectious RNA. Communication IV. Effect of O-methylhydroxylamine. Analysis of mutagenesis kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216082"} {"pmid": "4216083", "title": "Differential effect of Bacillis subtilis extracts on transformation with nonirradiated and UV-irradiated DNA.", "content": "Differential effect of Bacillis subtilis extracts on transformation with nonirradiated and UV-irradiated DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216083"} {"pmid": "4216085", "title": "Letter: Side-effects of maprotiline.", "content": "Letter: Side-effects of maprotiline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216085"} {"pmid": "4216087", "title": "Lactic acidosis in diabetics.", "content": "Lactic acidosis in diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216087"} {"pmid": "4216089", "title": "Detection of bladder-cancer-associated antigens in urine by micro-complement fixation.", "content": "Detection of bladder-cancer-associated antigens in urine by micro-complement fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216089"} {"pmid": "4216088", "title": "The nature and frequency of rugby injuries: a pilot study of 300 injuries at Stellenbosch.", "content": "The nature and frequency of rugby injuries: a pilot study of 300 injuries at Stellenbosch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216088"} {"pmid": "4216090", "title": "Reversal of seconardy lesions of diabetes in rats by pancreatic islet transplantation.", "content": "Reversal of seconardy lesions of diabetes in rats by pancreatic islet transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216090"} {"pmid": "4216091", "title": "Physiologic and immunologic status of long-functioning transplanted pancreatic islets in rats.", "content": "Physiologic and immunologic status of long-functioning transplanted pancreatic islets in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216091"} {"pmid": "4216092", "title": "Tissue culture of adult human islets of Langerhans for transplantation.", "content": "Tissue culture of adult human islets of Langerhans for transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216092"} {"pmid": "4216093", "title": "Enhancement of pancreatic islet allograft survival with ALS and donor bone marrow.", "content": "Enhancement of pancreatic islet allograft survival with ALS and donor bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216093"} {"pmid": "4216094", "title": "Prolonged relief from diabetes after syngeneic or allogeneic transplantation of isolated pancreatic islets in rats.", "content": "Prolonged relief from diabetes after syngeneic or allogeneic transplantation of isolated pancreatic islets in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216094"} {"pmid": "4216095", "title": "Edema formation and central hemorrhagic necrosis following impact injury to primate spinal cord.", "content": "Edema formation and central hemorrhagic necrosis following impact injury to primate spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216095"} {"pmid": "4216097", "title": "Histopathologic observations of labyrinthitis ossificans.", "content": "Histopathologic observations of labyrinthitis ossificans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216097"} {"pmid": "4216096", "title": "Wound healing and collagen degradation in calcium-EDTA-treated rats.", "content": "Wound healing and collagen degradation in calcium-EDTA-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216096"} {"pmid": "4216098", "title": "Casein hydrolysate and Intralipid vs casein hydrolysate and 25 percent glucose for hyperalimentation.", "content": "Casein hydrolysate and Intralipid vs casein hydrolysate and 25 percent glucose for hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216098"} {"pmid": "4216099", "title": "Arterial plasma amino acids in patients receiving an elemental diet.", "content": "Arterial plasma amino acids in patients receiving an elemental diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216099"} {"pmid": "4216100", "title": "The demands of hyperalimentation on splanchnic blood flow and oxygen consumption.", "content": "The demands of hyperalimentation on splanchnic blood flow and oxygen consumption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216100"} {"pmid": "4216101", "title": "Intravenous hyperalimentation and growth hormone in cancer patients.", "content": "Intravenous hyperalimentation and growth hormone in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216101"} {"pmid": "4216103", "title": "Effect of parenteral nutrition on body composition.", "content": "Effect of parenteral nutrition on body composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216103"} {"pmid": "4216102", "title": "Fat-carbohydrate interaction: effects on nitrogen-sparing in total intravenous feeding.", "content": "Fat-carbohydrate interaction: effects on nitrogen-sparing in total intravenous feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216102"} {"pmid": "4216104", "title": "Effect of taste on ingestion by human newborns.", "content": "Effect of taste on ingestion by human newborns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216104"} {"pmid": "4216105", "title": "4th Symposium on oral sensation and perception. Concluding comment I.", "content": "4th Symposium on oral sensation and perception. Concluding comment I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216105"} {"pmid": "4216116", "title": "Molecular aspects of the clottable proteins of human plasma during fibrinogenolysis.", "content": "Molecular aspects of the clottable proteins of human plasma during fibrinogenolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216116"} {"pmid": "4216117", "title": "Conditions for stabilization and determination of activated factor V.", "content": "Conditions for stabilization and determination of activated factor V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216117"} {"pmid": "4216120", "title": "A rapid and reliable micro-method of leukoagglutination using papain.", "content": "A rapid and reliable micro-method of leukoagglutination using papain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216120"} {"pmid": "4216122", "title": "Characterization of the venoms of various Bothrops species by immunoelectrophoresis and reaction with fibrinogen agarose.", "content": "Characterization of the venoms of various Bothrops species by immunoelectrophoresis and reaction with fibrinogen agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216122"} {"pmid": "4216121", "title": "Influence of calcium and magnesium ions on the sino-atrial node pacemaker activity of the canine heart.", "content": "Influence of calcium and magnesium ions on the sino-atrial node pacemaker activity of the canine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216121"} {"pmid": "4216125", "title": "Radiotherapy combined with hormone therapy for prostate cancer.", "content": "Radiotherapy combined with hormone therapy for prostate cancer. This is a preliminary report of megavoltage radiotherapy given at the Cancer Institute, Gunma University, and National Cancer Center Hospitals in Japan. Adenocarcinoma was demonstrated in 67 patients with prostate cancer. There were 4 in Stage A, 4 in Stage B, 38 Stage C, and 21 Stage D. 28 had received androgenic therapy before irradiation. 39 were irradiated first; hormone therapy was later given to 32 of these. Only 5 had radiotherapy alone. Chemotherapy was given to the others. Total tumor doses were 6000-8000 rd within 6-8 weeks. Techniques of irradiation varied at different hospitals. About 70% showed improved clinical findings. Undifferentiated adenocarcinoma was relatively more highly sensitive. Adverse symptoms occurred during radiotherapy; most were tolerable but in 9 cases irradiation was discontinued. In 6 it was resumed after 1-2 weeks. Intractable rectal bleeding was present in 2. Survival rates in the Stage C group were 60% at 3 years, 49.6% at 5 years. 5-year survival for the 24 cases with differentiated adenocarcinoma was histologically 58.8%, better than average survival rates in Japan. Some of the 21 Stage D cases showed improvement. Antiandrogenic therapy is indicated for well-differentiated carcinoma, but radiation therapy is best for undifferentiated tumors, which are less hormone-responsive. Combined therapy seems justified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216125"} {"pmid": "4216131", "title": "The significance of the bacterial count in pyelonephrititis due to Pseudomonas aeruginosa in animal experiments.", "content": "The significance of the bacterial count in pyelonephrititis due to Pseudomonas aeruginosa in animal experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216131"} {"pmid": "4216130", "title": "Renal clearance studies in the pig. Surgical procedures, performance of investigations and physiological data.", "content": "Renal clearance studies in the pig. Surgical procedures, performance of investigations and physiological data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216130"} {"pmid": "4216133", "title": "Radiologic examination of the esophagus in dogs and cats.", "content": "Radiologic examination of the esophagus in dogs and cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216133"} {"pmid": "4216135", "title": "Indications and selection of patients for radiation therapy.", "content": "Indications and selection of patients for radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216135"} {"pmid": "4216134", "title": "Radiographic contrast studies of the lower urinary tract.", "content": "Radiographic contrast studies of the lower urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216134"} {"pmid": "4216136", "title": "Toad venom toxicity and its clinical occurrence in small animals in the United Kingdom.", "content": "Toad venom toxicity and its clinical occurrence in small animals in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216136"} {"pmid": "4216138", "title": "Enterochromaffin cells of the mammalian small intestine as the source of motilin.", "content": "Enterochromaffin cells of the mammalian small intestine as the source of motilin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216138"} {"pmid": "4216139", "title": "Desmosomes in human seminiferous epithelium. An electron microscopic study.", "content": "Desmosomes in human seminiferous epithelium. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216139"} {"pmid": "4216140", "title": "Prevention of D-galactosamine-induced hepatocellular autophagocytosis by cycloheximide.", "content": "Prevention of D-galactosamine-induced hepatocellular autophagocytosis by cycloheximide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216140"} {"pmid": "4216141", "title": "Experimental modification of the mitogenic effect of methyl sterculate on rat liver.", "content": "Experimental modification of the mitogenic effect of methyl sterculate on rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216141"} {"pmid": "4216142", "title": "Effects of uremia and vitamin D on bone and the ultrastructure of thyroid parafollicular cells and parathyroid chief cells in the rat.", "content": "Effects of uremia and vitamin D on bone and the ultrastructure of thyroid parafollicular cells and parathyroid chief cells in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216142"} {"pmid": "4216143", "title": "Fetal hemopoiesis. II. Electron microscopic studies on human hepatic hemopoiesis.", "content": "Fetal hemopoiesis. II. Electron microscopic studies on human hepatic hemopoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216143"} {"pmid": "4216144", "title": "The permeability of the blood-testis barrier to lanthanum during the immune-induced aspermatogenesis and following vasectomy in the guinea-pig.", "content": "The permeability of the blood-testis barrier to lanthanum during the immune-induced aspermatogenesis and following vasectomy in the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216144"} {"pmid": "4216169", "title": "The planning of medical education programmes. Report of a WHO Expert Committee.", "content": "The planning of medical education programmes. Report of a WHO Expert Committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216169"} {"pmid": "4216170", "title": "Planning and organization of geriatric services. Report of a WHO Expert Committe.", "content": "Planning and organization of geriatric services. Report of a WHO Expert Committe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216170"} {"pmid": "4216172", "title": "WHO Expert Committee on Drug Dependence. Twentieth report.", "content": "WHO Expert Committee on Drug Dependence. Twentieth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216172"} {"pmid": "4216171", "title": "WHO Expert committe on Malaria.. Sixteenth report.", "content": "WHO Expert committe on Malaria.. Sixteenth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216171"} {"pmid": "4216173", "title": "WHO Expert Committee on Tuberculosis. Ninth report.", "content": "WHO Expert Committee on Tuberculosis. Ninth report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216173"} {"pmid": "4216174", "title": "Ecology and control of rodents of public health importance. Report of a WHO Scientific Group.", "content": "Ecology and control of rodents of public health importance. Report of a WHO Scientific Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216174"} {"pmid": "4216175", "title": "Detection of dependence-producing drugs in body fluids. Report of a WHO Meeting of Investigators.", "content": "Detection of dependence-producing drugs in body fluids. Report of a WHO Meeting of Investigators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216175"} {"pmid": "4216176", "title": "Evaluation of certain food additives. Eighteenth Report of the Joint FAO/WHO Expert Committee on Food Additives.", "content": "Evaluation of certain food additives. Eighteenth Report of the Joint FAO/WHO Expert Committee on Food Additives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216176"} {"pmid": "4216177", "title": "Community health nursing. Report of a WHO Expert Committee.", "content": "Community health nursing. Report of a WHO Expert Committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216177"} {"pmid": "4216178", "title": "New approaches in health statistics. Report of the Second International Conference of National Committees on Vital and Health Statistics.", "content": "New approaches in health statistics. Report of the Second International Conference of National Committees on Vital and Health Statistics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216178"} {"pmid": "4216188", "title": "Immunological determination of human fetal hemoglobin.", "content": "Immunological determination of human fetal hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216188"} {"pmid": "4216189", "title": "Comparison of 8 different colorimetric, radiochemical and immunological procedures for the determination of iron binding capacity.", "content": "Comparison of 8 different colorimetric, radiochemical and immunological procedures for the determination of iron binding capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216189"} {"pmid": "4216197", "title": "Serum thyroxine radioimmunoassay, simplified.", "content": "Serum thyroxine radioimmunoassay, simplified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216197"} {"pmid": "4216196", "title": "Experience with immunological TBG quantitation in the clinic.", "content": "Experience with immunological TBG quantitation in the clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216196"} {"pmid": "4216198", "title": "Comparison of different methods for the intensification of immunoprecipitates for the determination of trace proteins.", "content": "Comparison of different methods for the intensification of immunoprecipitates for the determination of trace proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216198"} {"pmid": "4216199", "title": "Incorporation of 14C- and 3H-L-leucine into immunoglobulins of different class specifity (radial-diffusion method).", "content": "Incorporation of 14C- and 3H-L-leucine into immunoglobulins of different class specifity (radial-diffusion method).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216199"} {"pmid": "4216200", "title": "A radioimmunoassay for erythropoietin.", "content": "A radioimmunoassay for erythropoietin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216200"} {"pmid": "4216201", "title": "Immunoglobulins of human prostatic fluid in prostatitis.", "content": "Immunoglobulins of human prostatic fluid in prostatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216201"} {"pmid": "4216202", "title": "Carbonic anhydrase: a new method of detection on polyacrylamide gels using conductivity measurements.", "content": "Carbonic anhydrase: a new method of detection on polyacrylamide gels using conductivity measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216202"} {"pmid": "4216203", "title": "Cryptosporidium agni sp.n. from lambs, and cryptosporidium bovis sp.n. from a calf, with observations on the oocyst.", "content": "Cryptosporidium agni sp.n. from lambs, and cryptosporidium bovis sp.n. from a calf, with observations on the oocyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216203"} {"pmid": "4216218", "title": "Isolation of IgA and of a fast subfraction of IgG from human placenta extract.", "content": "Isolation of IgA and of a fast subfraction of IgG from human placenta extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216218"} {"pmid": "4216219", "title": "Zinc enzymes in commercial Pronase-P. Further characterization of the heterogeneity of the proteolytic enzymes of the K-1 strain of Streptomyces griseus.", "content": "Zinc enzymes in commercial Pronase-P. Further characterization of the heterogeneity of the proteolytic enzymes of the K-1 strain of Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216219"} {"pmid": "4216220", "title": "Estimation of the dimensions within the \"pore system\" in human skeletal muscle capillaries.", "content": "Estimation of the dimensions within the \"pore system\" in human skeletal muscle capillaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216220"} {"pmid": "4216224", "title": "Subacute sclerosing panencephalitis: Fab-fragments and antigens.", "content": "Subacute sclerosing panencephalitis: Fab-fragments and antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216224"} {"pmid": "4216227", "title": "Genealogical blood-group analyses of the Danzig quintuplets.", "content": "Genealogical blood-group analyses of the Danzig quintuplets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216227"} {"pmid": "4216228", "title": "Course of serologic incompatibility in twin fetuses.", "content": "Course of serologic incompatibility in twin fetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216228"} {"pmid": "4216229", "title": "Histochemical clues to problems in glucose homeostasis. The glucogenic potential of peripheral tissues and glucose-6-phosphatase activity.", "content": "Histochemical clues to problems in glucose homeostasis. The glucogenic potential of peripheral tissues and glucose-6-phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216229"} {"pmid": "4216231", "title": "Cytochemical observations on the vitellogenetic oocytes of Palaemon adspersus Rathke (crust. dec.).", "content": "Cytochemical observations on the vitellogenetic oocytes of Palaemon adspersus Rathke (crust. dec.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216231"} {"pmid": "4216225", "title": "The occurrence of vaginal diphtheroids in Papanicolaou smears.", "content": "The occurrence of vaginal diphtheroids in Papanicolaou smears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216225"} {"pmid": "4216232", "title": "Non-specific esterase and its involvement in the dynamism of outer body covering of trematodes, cestodes and nematodes (series I).", "content": "Non-specific esterase and its involvement in the dynamism of outer body covering of trematodes, cestodes and nematodes (series I).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216232"} {"pmid": "4216234", "title": "Characterization of fluorescein isothiocyanate: synthesis and testing methods for fluorescein isothiocyanate isomeres.", "content": "Characterization of fluorescein isothiocyanate: synthesis and testing methods for fluorescein isothiocyanate isomeres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216234"} {"pmid": "4216235", "title": "Tetracycline-labelling as a method for detecting the bone demineralization of parathormone-treated rats.", "content": "Tetracycline-labelling as a method for detecting the bone demineralization of parathormone-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216235"} {"pmid": "4216236", "title": "Histoenzymological demonstration of acid phosphatase in the gizzard of Cinnyris asiatica, Megalaima haemacephala and Upupa epops.", "content": "Histoenzymological demonstration of acid phosphatase in the gizzard of Cinnyris asiatica, Megalaima haemacephala and Upupa epops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216236"} {"pmid": "4216226", "title": "Decreased antidiuretic response to lysine-vasopressin after acute administration of glibenclamide in healthy subjects.", "content": "Decreased antidiuretic response to lysine-vasopressin after acute administration of glibenclamide in healthy subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216226"} {"pmid": "4216238", "title": "Histochemistry of hydroxysteroid dehydrogenases in the kidneys of chameleon, python and crocodile.", "content": "Histochemistry of hydroxysteroid dehydrogenases in the kidneys of chameleon, python and crocodile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216238"} {"pmid": "4216239", "title": "Letter: Salivary IgA in periodontal disease.", "content": "Letter: Salivary IgA in periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216239"} {"pmid": "4216240", "title": "Plasma progesterone levels in normal and abnormal pregnancies.", "content": "Plasma progesterone levels in normal and abnormal pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216240"} {"pmid": "4216241", "title": "The significance of the glomeruli-bound anti-renal basement membrane active antibody as the pathogenetic factor of human chronic glomerulonephritis.", "content": "The significance of the glomeruli-bound anti-renal basement membrane active antibody as the pathogenetic factor of human chronic glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216241"} {"pmid": "4216242", "title": "Neurofibromatosis complicated by intracranial tumors.", "content": "Neurofibromatosis complicated by intracranial tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216242"} {"pmid": "4216243", "title": "The diagnosis of pleuro-pulmonary lesions utilizing contrast pleurography.", "content": "The diagnosis of pleuro-pulmonary lesions utilizing contrast pleurography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216243"} {"pmid": "4216244", "title": "Immunoglobulin analysis in families of myeloma patients.", "content": "Immunoglobulin analysis in families of myeloma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216244"} {"pmid": "4216245", "title": "Long-term conservative therapy of chronic AV block.", "content": "Long-term conservative therapy of chronic AV block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216245"} {"pmid": "4216246", "title": "Idiopathic light chain dyscrasia--a new distinct entity? Report of a case.", "content": "Idiopathic light chain dyscrasia--a new distinct entity? Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216246"} {"pmid": "4216251", "title": "Requirements for sterility testing of oral bacterial vaccines.", "content": "Requirements for sterility testing of oral bacterial vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216251"} {"pmid": "4216252", "title": "Self-experiments with ingestion of various bacteria.", "content": "Self-experiments with ingestion of various bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216252"} {"pmid": "4216255", "title": "Intra-uterine diagnosis of birth defects.", "content": "Intra-uterine diagnosis of birth defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216255"} {"pmid": "4216256", "title": "Melanocyte-stimulating hormone and the hypothalamic hormone which inhibits its release.", "content": "Melanocyte-stimulating hormone and the hypothalamic hormone which inhibits its release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216256"} {"pmid": "4216257", "title": "L-DOPA and the control of prolactin secretion.", "content": "L-DOPA and the control of prolactin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216257"} {"pmid": "4216259", "title": "Dopaminergic and cholinergic mechanisms in relation to postural tremor in the monkey and circling movements in the cat.", "content": "Dopaminergic and cholinergic mechanisms in relation to postural tremor in the monkey and circling movements in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216259"} {"pmid": "4216258", "title": "The effect of L-DOPA on the hypothalamic-pituitary-thyroid axis.", "content": "The effect of L-DOPA on the hypothalamic-pituitary-thyroid axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216258"} {"pmid": "4216260", "title": "Characterisation of macroglobulins IgM aggregates.", "content": "Characterisation of macroglobulins IgM aggregates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216260"} {"pmid": "4216262", "title": "Letter: Hyperglycemia without ketosis or hypernatremia.", "content": "Letter: Hyperglycemia without ketosis or hypernatremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216262"} {"pmid": "4216261", "title": "Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. III. Entero-endocrine cells.", "content": "Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. III. Entero-endocrine cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216261"} {"pmid": "4216263", "title": "Fatty liver produced by hyperalimentation of rats.", "content": "Fatty liver produced by hyperalimentation of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216263"} {"pmid": "4216264", "title": "Chronic mesenteric arterial insufficiency caused by vascular neurofibromatosis. A case report.", "content": "Chronic mesenteric arterial insufficiency caused by vascular neurofibromatosis. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216264"} {"pmid": "4216265", "title": "Immunological studies of beta galactosidase in normal human liver and in GM1 gangliosidosis.", "content": "Immunological studies of beta galactosidase in normal human liver and in GM1 gangliosidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216265"} {"pmid": "4216266", "title": "A comparison of the safety and efficiency of three intermittent intravenous therapy systems--the minibottle, the minibag and the inline burette.", "content": "A comparison of the safety and efficiency of three intermittent intravenous therapy systems--the minibottle, the minibag and the inline burette.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216266"} {"pmid": "4216267", "title": "In vivo neutron activation analysis. Clinical potential in body composition studies.", "content": "In vivo neutron activation analysis. Clinical potential in body composition studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216267"} {"pmid": "4216268", "title": "Effects of nitroglycerin on left ventricular cavitary size and cardiac performance determined by ultrasound in man.", "content": "Effects of nitroglycerin on left ventricular cavitary size and cardiac performance determined by ultrasound in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216268"} {"pmid": "4216270", "title": "Development of acute erythroleukemia in B-cell immunoproliferative disorders after prolonged therapy with alkylating drugs.", "content": "Development of acute erythroleukemia in B-cell immunoproliferative disorders after prolonged therapy with alkylating drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216270"} {"pmid": "4216269", "title": "Biologic and clinical significance of cryoglobulins. A report of 86 cases.", "content": "Biologic and clinical significance of cryoglobulins. A report of 86 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216269"} {"pmid": "4216271", "title": "Letter: Corneal cells in penetrating keratoplasty.", "content": "Letter: Corneal cells in penetrating keratoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216271"} {"pmid": "4216272", "title": "Role of carbonic anhydrase in urinary acidification by the toad bladder.", "content": "Role of carbonic anhydrase in urinary acidification by the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216272"} {"pmid": "4216273", "title": "Excretion and retention of cadmium, zinc, and mercury by rabbit kidney.", "content": "Excretion and retention of cadmium, zinc, and mercury by rabbit kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216273"} {"pmid": "4216274", "title": "Hyperalimentation as a treatment of Crohn's disease.", "content": "Hyperalimentation as a treatment of Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216274"} {"pmid": "4216279", "title": "Serum immunoglobulin M in chronic urticaria.", "content": "Serum immunoglobulin M in chronic urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216279"} {"pmid": "4216280", "title": "Intermittent positive pressure breathing in management of chronic obstructive pulmonary disease: current state of the art.", "content": "Intermittent positive pressure breathing in management of chronic obstructive pulmonary disease: current state of the art.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216280"} {"pmid": "4216282", "title": "The influence of electrical current on an infecting microorganism in wounds.", "content": "The influence of electrical current on an infecting microorganism in wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216282"} {"pmid": "4216283", "title": "Band keratopathy in mercury exposure.", "content": "Band keratopathy in mercury exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216283"} {"pmid": "4216284", "title": "Immunofluorescent test in bullous diseases of skin and mucous membranes.", "content": "Immunofluorescent test in bullous diseases of skin and mucous membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216284"} {"pmid": "4216286", "title": "Characterization of lac+ transductants of Streptococcus lactis.", "content": "Characterization of lac+ transductants of Streptococcus lactis. A phage-mediated transducing system was used in studying certain physiological characteristics of S. lactis C2 wild type, lactose-negative mutants, and lactose-positive transductants. Lac(-) mutants, obtained by acriflavine treatment of the wild type, were similar to the wild type in all characteristics tested except they lacked beta-D-phosphogalactoside galactohydrolase (beta-Pgal) and could not transport [(14)C]lactose; they also had approximately 10% of the proteolytic ability than wild-type cells. The lactose-fermenting characteristic was transduced from the wild type to Lac(-) mutants. The Lac(+) transductants obtained were similar to the wild-type parent with respect to lactose fermentation and level of beta-Pgal activity (0.186 U of protein per mg). These transductants, however, had not regained full proteolytic ability and were similar to the Lac(-) mutant in this respect. Lactic acid production of the transductants in milk was approximately two-thirds that of the wild type. Data suggest that both the lactose-fermenting and proteolytic characters are carried on extrachromasomal particles (plasmids).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216286"} {"pmid": "4216287", "title": "Aspergillus flavus infection and aflatoxin production in corn: influence of trace elements.", "content": "Aspergillus flavus infection and aflatoxin production in corn: influence of trace elements. Distribution of trace element levels in corn germ fractions from kernels naturally infected with Aspergillus flavus and from kernels free of the fungus demonstrated an association between the presence of A. flavus and higher levels of metals. A. flavus production of aflatoxin on various autoclaved corn media showed that ground, whole corn was an excellent substrate; similar high levels of toxin were observed on full-fat corn germ but endosperm and defatted corn germ supported reduced yields. The influence of trace elements and their availability in defatted corn germ to A. flavus-mediated aflatoxin biosynthesis were measured. Enrichment of the substrate with 5 to 10 mug of manganese, copper, cadmium, or chromium per g of germ increased toxin yields. Addition of lead or zinc (50 to 250 mug/g) also enhanced toxin accumulation. Aflatoxin elaboration was reduced by the addition of 25 mug of cadmium per g or 500 mug of copper per g of germ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216287"} {"pmid": "4216288", "title": "Microculture plaque neutralization test for California group arboviruses.", "content": "Microculture plaque neutralization test for California group arboviruses. A microculture plaque neutralization test is described for California-group arboviruses that is as precise and quantitative as the standard test conducted in 60-mm petri dishes. It was shown that there was no significant between-panel or between-day variation in determinations and that a single pipette could be used for all serum-dilution levels within a titration without inoculum carry-over effect. The experimental protocol and statistical methods used produce 50% neutralization end points that meet the assumptions of parametric statistics. This permits the power and versatility of the analysis of variance to be exploited in testing for treatment effects in serological and immunological studies with viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216288"} {"pmid": "4216289", "title": "Diagnosis of California (La Crosse) encephalitis by precipitin techniques: a prospective study.", "content": "Diagnosis of California (La Crosse) encephalitis by precipitin techniques: a prospective study. Counterelectrophoresis (CEP) and immunodiffusion (ID) were evaluated prospectively as methods for the early and rapid laboratory diagnosis of California encephalitis (CE). CEP and ID studies were done on paired sera from 127 patients with acute central nervous system infections. After the precipitin tests were completed, conventional hemagglutination-inhibition, neutralizing, and complement fixing antibody titers were measured. The CEP system detected antibodies in 7 (41%) of 17 CE patients during their acute illness and in all 17 patients during convalescence. The ID method was less sensitive; 3 of 17 acute sera and 16 of 17 convalescent sera were ID positive. Comparative precipitin studies indicated that La Crosse virus was the infecting California group subtype in all 17 CE patients. Because CEP can be performed in 1.5 h, is at least as sensitive as hemagglutination-inhibition, neutralizing, and complement fixing tests, and can detect prospectively 41% of CE patients during their acute illness, it is recommended as a rapid diagnostic test for CE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216289"} {"pmid": "4216290", "title": "Corynebacterial kidney disease of salmonids: growth and serological studies on the causative bacterium.", "content": "Corynebacterial kidney disease of salmonids: growth and serological studies on the causative bacterium. Comparative growth studies of 10 isolates of the Corynebacterium of salmonid kidney disease were quantified on four media. Greatest cell yield was obtained from Mueller-Hinton medium with 0.1% L-cysteine hydrochloride. Serological tests, in which rabbit antisera used against typical bacteria strains showed all to be antigenically homologous, provided a reliable method of identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216290"} {"pmid": "4216291", "title": "Factors that influence microbial contamination of fluids associated with hemodialysis machines.", "content": "Factors that influence microbial contamination of fluids associated with hemodialysis machines. Studies were conducted on the microbiological quality of fluids associated with different types of dialysis systems located in six dialysis centers and 14 homes. Included were (i) single-pass systems employing either parallel flow (Kiil or Gambro) or capillary cartridge dialyzers and (ii) recirculating single-pass and batch recirculating systems using coil dialyzers. Microbiological assays were performed on the water used to prepare dialysis fluid, the concentrated dialysate, and either pre- and postdialyzer dialysate (single-pass systems) or the dialysate contained in storage reservoirs and recirculating cannisters (recirculating systems). The levels of microbial contamination consisting of gram-negative bacteria were directly related to the type of dialysis system, method of water treatment, distribution system, and in some instances, the type of dialyzer. Recirculating single-pass and batch recirculating systems consistently contained significantly higher levels of contamination than single-pass systems. These results were directly related to the design of recirculating systems which permits carbon- and nitrogen-containing waste products dialyzed from the patient to accumulate, be used as nutrients by microorganisms, and subsequently allow for 2- to 4-log increases in contamination levels during a dialysis treatment. In contrast, levels of contamination in single-pass machines were related more to the quality of the water used to prepare dialysis fluid and the adequacy of cleaning and disinfection procedures than to the design of the system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216291"} {"pmid": "4216292", "title": "Simplified extraction procedure for serological grouping of beta-hemolytic streptococci.", "content": "Simplified extraction procedure for serological grouping of beta-hemolytic streptococci. An adaptation of the nitrous acid extraction of streptococci proved to be a reliable and practical method for the preparation of extracts for routine serological group identification. The extracts of all groups tested gave strong capillary precipitin reactions as well as reactions of double diffusion in gel. For routine grouping, extracts were prepared from the first one-half-plate subculture of the initial throat culture. The technique is simple and reliable, and it requires a minimum of technical skill, reagents, and equipment. Its use would facilitate epidemiological surveillance of group A streptococci and rapid diagnosis of streptococcal infections at a low cost.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216292"} {"pmid": "4216293", "title": "The relationship of mouse spermatozoal to mouse testicular cathepsins.", "content": "The relationship of mouse spermatozoal to mouse testicular cathepsins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216293"} {"pmid": "4216294", "title": "Reaction of human chorionic somatomammotropin and human pituitary growth hormone with tetranitromethane at 0 degrees C.", "content": "Reaction of human chorionic somatomammotropin and human pituitary growth hormone with tetranitromethane at 0 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216294"} {"pmid": "4216295", "title": "Cholesterol-7 alpha-hydroxylase of pigeon liver microsomes.", "content": "Cholesterol-7 alpha-hydroxylase of pigeon liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216295"} {"pmid": "4216296", "title": "Xanthine phosphoribosyltransferase from Streptococcus faecalis. Properties and specificity.", "content": "Xanthine phosphoribosyltransferase from Streptococcus faecalis. Properties and specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216296"} {"pmid": "4216297", "title": "Action of phospholipase A2 and phospholipase C on Escherichia coli.", "content": "Action of phospholipase A2 and phospholipase C on Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216297"} {"pmid": "4216298", "title": "The P700-chlorophyll a-protein. Isolation and some characteristics of the complex in higher plants.", "content": "The P700-chlorophyll a-protein. Isolation and some characteristics of the complex in higher plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216298"} {"pmid": "4216299", "title": "Effect of nalidixic acid on Euglena gracilis: induced loss of chloroplast deoxyribonucleic acid.", "content": "Effect of nalidixic acid on Euglena gracilis: induced loss of chloroplast deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216299"} {"pmid": "4216300", "title": "Association and dissociation of phycocyanin by small molecules.", "content": "Association and dissociation of phycocyanin by small molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216300"} {"pmid": "4216301", "title": "Interaction of the components of the lactose synthetase system.", "content": "Interaction of the components of the lactose synthetase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216301"} {"pmid": "4216302", "title": "The activation of rabbit muscle, liver, and kidney fructose bisphosphatases by histidine and citrate.", "content": "The activation of rabbit muscle, liver, and kidney fructose bisphosphatases by histidine and citrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216302"} {"pmid": "4216303", "title": "Human liver carboxylesterase. Purification and molecular properties.", "content": "Human liver carboxylesterase. Purification and molecular properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216303"} {"pmid": "4216304", "title": "Alternate pathways of linolenic acid biosynthesis in growing cultures of Penicillium chrysogenum.", "content": "Alternate pathways of linolenic acid biosynthesis in growing cultures of Penicillium chrysogenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216304"} {"pmid": "4216305", "title": "Serum IgG levels in feto-fetal transfusion syndrome.", "content": "Serum IgG levels in feto-fetal transfusion syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216305"} {"pmid": "4216306", "title": "Trial comparing D-penicillamine and gold in rheumatoid arthritis. Preliminary report.", "content": "Trial comparing D-penicillamine and gold in rheumatoid arthritis. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216306"} {"pmid": "4216309", "title": "Residual fraction and the inotropic state of the left ventricle.", "content": "Residual fraction and the inotropic state of the left ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216309"} {"pmid": "4216310", "title": "A comparison of the effects of some inotropic and chronotropic agents on isolated atria from normotensive (NTR) and spontaneously hypertensive (SHR) rats.", "content": "A comparison of the effects of some inotropic and chronotropic agents on isolated atria from normotensive (NTR) and spontaneously hypertensive (SHR) rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216310"} {"pmid": "4216311", "title": "[Isoenzyme methods in the differentiation of human and monkey blood].", "content": "[Isoenzyme methods in the differentiation of human and monkey blood].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216311"} {"pmid": "4216333", "title": "Modulation by fumarate of a Pi-insensitive pyruvate kinase from Rhodopseudomonas capsulata.", "content": "Modulation by fumarate of a Pi-insensitive pyruvate kinase from Rhodopseudomonas capsulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216333"} {"pmid": "4216335", "title": "Influence of glass microbeads on growth, activity and morphological changes of Bacillus megaterium.", "content": "Influence of glass microbeads on growth, activity and morphological changes of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216335"} {"pmid": "4216336", "title": "Flexibacter elegans and Myxococcus fulvus: aerobic Gram-negative bacteria containing menaquinones as the only isoprenoid quinones.", "content": "Flexibacter elegans and Myxococcus fulvus: aerobic Gram-negative bacteria containing menaquinones as the only isoprenoid quinones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216336"} {"pmid": "4216340", "title": "Intensive treatment of the adolescent and his family.", "content": "Intensive treatment of the adolescent and his family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216340"} {"pmid": "4216341", "title": "Rubella precipitin response in natural infection and in vaccination.", "content": "Rubella precipitin response in natural infection and in vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216341"} {"pmid": "4216343", "title": "The antiviral activity of some related benzo(b) thiophene derivatives. II. Anti-influenza activity.", "content": "The antiviral activity of some related benzo(b) thiophene derivatives. II. Anti-influenza activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216343"} {"pmid": "4216342", "title": "Pinocytotic uptake and intralysosomal crystal formation of coxsackievirus A9 in monkey kidney cells. An electron microscopic autoradiographic study.", "content": "Pinocytotic uptake and intralysosomal crystal formation of coxsackievirus A9 in monkey kidney cells. An electron microscopic autoradiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216342"} {"pmid": "4216346", "title": "Pathogenesis of lead encephalopathy. Uptake of lead and reaction of brain capillaries.", "content": "Pathogenesis of lead encephalopathy. Uptake of lead and reaction of brain capillaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216346"} {"pmid": "4216347", "title": "Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.", "content": "Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216347"} {"pmid": "4216350", "title": "Purification of antibodies to protein hormones by affinity chromatography on divinylsulfonyl sepharose.", "content": "Purification of antibodies to protein hormones by affinity chromatography on divinylsulfonyl sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216350"} {"pmid": "4216349", "title": "Studies on the effects of insulin and acetylcholine on activation of glycogen synthase and on glycogenesis in hepatocytes.", "content": "Studies on the effects of insulin and acetylcholine on activation of glycogen synthase and on glycogenesis in hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216349"} {"pmid": "4216351", "title": "D-ribulose 1, 5-diphosphate carboxylase from blue-green algae.", "content": "D-ribulose 1, 5-diphosphate carboxylase from blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216351"} {"pmid": "4216348", "title": "The distribution of L-asparagine synthetase in the principal organs of several mammalian and avian species.", "content": "The distribution of L-asparagine synthetase in the principal organs of several mammalian and avian species. A survey was conducted of the distribution of l-asparagine synthetase and of l-asparaginase in the principal organs of representative mammals and birds. Although a radiometric assay was used as a routine, several additional criteria, including enzymic and chromatographic ones, were used to verify that the product of the synthetase was l-asparagine. Recoveries of exogenous l-asparagine were assessed in the presence of a number of mouse organs and found to be about 85%. In addition, evidence is presented for the existence in mouse liver of a thermolabile activity capable of destroying l-asparagine and stimulated by high concentrations of NH(4) (+) ions. Of the organs surveyed, pancreas was generally found to synthesize l-asparagine at the most rapid rate, whereas extracts of liver catalysed the decomposition of this amide at the greatest velocity. Of the species studied, guinea pig had the highest activities of pancreatic l-asparagine synthetase and also of hepatic l-asparaginase. The pancreas of mouse and ox also were good sources of l-asparagine synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216348"} {"pmid": "4216354", "title": "Anti-complement effects of two anti-inflammatory agents. Niflumic and flufenamic acids.", "content": "Anti-complement effects of two anti-inflammatory agents. Niflumic and flufenamic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216354"} {"pmid": "4216355", "title": "Catalytic activity and inhibition of carbonic anhydrase of rat tissues.", "content": "Catalytic activity and inhibition of carbonic anhydrase of rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216355"} {"pmid": "4216356", "title": "Drug metabolism in Gunn rats: inability to increase bilirubin glucuronidation by phenobarbital treatment.", "content": "Drug metabolism in Gunn rats: inability to increase bilirubin glucuronidation by phenobarbital treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216356"} {"pmid": "4216357", "title": "The prosthetic treatment of hepatitis B antigen positive patients.", "content": "The prosthetic treatment of hepatitis B antigen positive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216357"} {"pmid": "4216358", "title": "Letter: 'The prevention of transmission of serum hepatitis in dentistry'.", "content": "Letter: 'The prevention of transmission of serum hepatitis in dentistry'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216358"} {"pmid": "4216359", "title": "Low right ventricular endocardial potentials in chronic Chagas' disease.", "content": "Low right ventricular endocardial potentials in chronic Chagas' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216359"} {"pmid": "4216360", "title": "Gastrointestinal haemorrhage from ectopic gastric mucosa lining a jejunal diverticulum.", "content": "Gastrointestinal haemorrhage from ectopic gastric mucosa lining a jejunal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216360"} {"pmid": "4216362", "title": "Sporadic G6PD deficiency with haemolytic anaemia in two children of West European ancestry.", "content": "Sporadic G6PD deficiency with haemolytic anaemia in two children of West European ancestry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216362"} {"pmid": "4216361", "title": "Aspects of the structure and clinical role of the carcinoembryonic antigen (CEA) and related macromolecules with particular reference to urothelial carcinoma.", "content": "Aspects of the structure and clinical role of the carcinoembryonic antigen (CEA) and related macromolecules with particular reference to urothelial carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216361"} {"pmid": "4216363", "title": "The role of complement in endotoxin shock and disseminated intravascular coagulation: experimental observations in the dog.", "content": "The role of complement in endotoxin shock and disseminated intravascular coagulation: experimental observations in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216363"} {"pmid": "4216364", "title": "Purification and properties of calf liver aldose reductase.", "content": "Purification and properties of calf liver aldose reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216364"} {"pmid": "4216365", "title": "On the activation of microsomal UDPglucuronyltransferase by phospholipase A.", "content": "On the activation of microsomal UDPglucuronyltransferase by phospholipase A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216365"} {"pmid": "4216366", "title": "Subunit structure and catalytic activity of pig kidney alkaline phosphatase.", "content": "Subunit structure and catalytic activity of pig kidney alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216366"} {"pmid": "4216367", "title": "Presence of a gelatin-specific proteinase and its latent form in human leucocytes.", "content": "Presence of a gelatin-specific proteinase and its latent form in human leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216367"} {"pmid": "4216369", "title": "Binding of 63Ni to rabbit serum alpha1-macroglobulin in vivo and in vitro.", "content": "Binding of 63Ni to rabbit serum alpha1-macroglobulin in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216369"} {"pmid": "4216370", "title": "Histochemical observations on the localization of some enzymes associated with digestion in four species of Brazilian nemerteans.", "content": "Histochemical observations on the localization of some enzymes associated with digestion in four species of Brazilian nemerteans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216370"} {"pmid": "4216373", "title": "Molecular weight determination of bovine carbonic anhydrase.", "content": "Molecular weight determination of bovine carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216373"} {"pmid": "4216374", "title": "Conformational analysis of thyrotropin releasing factor by proton magnetic resonance spectroscopy.", "content": "Conformational analysis of thyrotropin releasing factor by proton magnetic resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216374"} {"pmid": "4216375", "title": "Conformational studies on the hypothalamic thyrotropin releasing factor and related compounds by 1-H nuclear magnetic resonance spectroscopy.", "content": "Conformational studies on the hypothalamic thyrotropin releasing factor and related compounds by 1-H nuclear magnetic resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216375"} {"pmid": "4216376", "title": "The determination of sequence information in homologously related proteins by mass spectrometry.", "content": "The determination of sequence information in homologously related proteins by mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216376"} {"pmid": "4216377", "title": "Properties of ribulose diphosphate carboxylase immobilized on porous glass.", "content": "Properties of ribulose diphosphate carboxylase immobilized on porous glass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216377"} {"pmid": "4216378", "title": "studies on aminoacylase immobilized on porous ceramic carriers.", "content": "studies on aminoacylase immobilized on porous ceramic carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216378"} {"pmid": "4216381", "title": "Immunodepressive action of oncogenic virus SA7 (C8).", "content": "Immunodepressive action of oncogenic virus SA7 (C8).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216381"} {"pmid": "4216382", "title": "Zinc and insulin content in pancreatic islets of rats after administration of hypoglycemic sulfonamides.", "content": "Zinc and insulin content in pancreatic islets of rats after administration of hypoglycemic sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216382"} {"pmid": "4216384", "title": "A sensitive and specific assay for cystathionine: cystathionine content of several plant tissues.", "content": "A sensitive and specific assay for cystathionine: cystathionine content of several plant tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216384"} {"pmid": "4216383", "title": "The use of anti-immunoglobulin for the immunoprecipitation of labeled proteins from tissue homogenates.", "content": "The use of anti-immunoglobulin for the immunoprecipitation of labeled proteins from tissue homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216383"} {"pmid": "4216385", "title": "Proceedings: Structure-activity relationships in the sulphonamide-carbonic anhydrase systems.", "content": "Proceedings: Structure-activity relationships in the sulphonamide-carbonic anhydrase systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216385"} {"pmid": "4216386", "title": "The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles.", "content": "The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles. 1 The distribution kinetics of [(14)C]-edrophonium were studied in both normal Wistar and homozygous Gunn rats with ligated renal pedicles.2 After intravenous injection the plasma concentration-time curve of [(14)C]-edrophonium was adequately fitted by a triexponential function in both species of rat and interpreted in terms of a three compartment model.3 The influence of the route of administration (i.e., systemic venous versus hepatic portal) of [(14)C]-edrophonium on its concentration in plasma was studied in normal Wistar rats with ligated renal pedicles. There was a marked difference in the area under the plasma concentration-time curve depending on the route of administration.4 The parameters of the model were determined and compared.5 The value of the metabolism rate constant was approximately the same in both species of rat. This suggests that the rate of conjugation of [(14)C]-edrophonium is unaltered in the homozygous Gunn rat despite the genetic lesion in UDP-glucuronyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216386"} {"pmid": "4216387", "title": "Sticky eye in the newborn.", "content": "Sticky eye in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216387"} {"pmid": "4216388", "title": "Lacticacidosis, ketoacidosis, and hyperalaninaemia in a phenformintreated diabetic patient.", "content": "Lacticacidosis, ketoacidosis, and hyperalaninaemia in a phenformintreated diabetic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216388"} {"pmid": "4216389", "title": "Studies on whole-body potassium in non-ketoacidotic diabetics before and after treatment.", "content": "Studies on whole-body potassium in non-ketoacidotic diabetics before and after treatment. Serial measurements of whole-body potassium were carried out in 28 diabetic patients, in 23 of whom diabetes had only recently been diagnosed. Eleven patients were treated with insulin, 12 with oral hypoglycaemic agents, and the rest were already on oral hypoglycaemic agents and had developed poor diabetic control; four of these required insulin. Whole-body potassium was measured before treatment was begun (or altered) and again one and six weeks later. Whole-body potassium (ratio of observed to expected) was initially reduced in most of the patients requiring insulin. After control of diabetes whole-body potassium increased significantly in the three groups. The increase in whole-body potassium in the individual patients varied over a wide range, and in patients who were treated with insulin it was often of a similar magnitude to that observed in patients in diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216389"} {"pmid": "4216391", "title": "Letter: Pseudomonas septicaemia following superficial colonization.", "content": "Letter: Pseudomonas septicaemia following superficial colonization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216391"} {"pmid": "4216390", "title": "Immunodiagnosis of snake bite.", "content": "Immunodiagnosis of snake bite. Management of a patient with snake bite is influenced by the nature of the offending snake. Species diagnosis based on the patient's history and physical signs is often unreliable and the possibility of making a species diagnosis by immunological means has therefore been investigated. Wound aspirates, blister fluids, sera, and urine samples from patients with snake bite were examined for the presence of species-specific venoms using immunodiffusion. A positive species diagnosis was made in 40 out of 101 patients. Immunodiagnosis was especially successful in patients bitten by the puff adder, Bitis arietans, and the African spitting cobra, Naja nigricollis. A higher success rate could probably be achieved using more specific antisera and more sensitive assay techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216390"} {"pmid": "4216393", "title": "Active insoluble prostatic phosphatase cocrosslinked with bovine serum albumin by glutaraldehyde.", "content": "Active insoluble prostatic phosphatase cocrosslinked with bovine serum albumin by glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216393"} {"pmid": "4216398", "title": "Photosynthesis and nitrogenase activity in the blue-green alga Gloeocapsa.", "content": "Photosynthesis and nitrogenase activity in the blue-green alga Gloeocapsa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216398"} {"pmid": "4216399", "title": "Action of chlorpromazine on spore-forming Bacillus species.", "content": "Action of chlorpromazine on spore-forming Bacillus species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216399"} {"pmid": "4216400", "title": "Plaque formation in Bacillus subtilis, and growth inhibition of Bacillus subtilis and Sarcina sp., induced by Schizophyllum commune.", "content": "Plaque formation in Bacillus subtilis, and growth inhibition of Bacillus subtilis and Sarcina sp., induced by Schizophyllum commune.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216400"} {"pmid": "4216403", "title": "A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster.", "content": "A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216403"} {"pmid": "4216404", "title": "Isolation and characterization of polysomes from Chironomus salivary glands.", "content": "Isolation and characterization of polysomes from Chironomus salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216404"} {"pmid": "4216394", "title": "Ovarian cancer.", "content": "Ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216394"} {"pmid": "4216397", "title": "Resection of head of pancreas and duodenum for carcinoma--pancreatoduodenectomy.", "content": "Resection of head of pancreas and duodenum for carcinoma--pancreatoduodenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216397"} {"pmid": "4216402", "title": "An ultrastructural study of the juxtaglomerular apparatus in the toad, bufo bufo.", "content": "An ultrastructural study of the juxtaglomerular apparatus in the toad, bufo bufo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216402"} {"pmid": "4216406", "title": "N-oxidation and demethylation of N,N-dimethylaniline by rabbit liver and lung microsomes. Effects of age and metals.", "content": "N-oxidation and demethylation of N,N-dimethylaniline by rabbit liver and lung microsomes. Effects of age and metals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216406"} {"pmid": "4216396", "title": "[Alexander Brunschwig (1901-1969)].", "content": "[Alexander Brunschwig (1901-1969)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216396"} {"pmid": "4216395", "title": "Special report: chemical carcinogenesis.", "content": "Special report: chemical carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216395"} {"pmid": "4216407", "title": "A comparison of African and European serum levels of immunoglobulin E.", "content": "A comparison of African and European serum levels of immunoglobulin E. The mean level of serum IgE in Nigerian blood donors is significantly higher than those in expatriates living in Nigeria and in Swiss blood donors. The examination of serum IgE levels (by the radioactive single radial diffusion technique) in Nigerian patients with different diseases, in asthmatic children with matched controls in Ghana, and in subjects from malarious and non-malarious areas of Tanzania indicates that high IgE levels in Africans may not be due to malaria, vesical schistosomiasis, or onchocerciasis infections. A marked difference, however, was found between African subjects with positive and negative findings of stool parasites; they had higher and lower mean levels of serum IgE, respectively. It seems that, in an African population where the serum IgE levels are raised for other reasons, a rise in IgE in association with allergic conditions such as asthma may not be apparent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216407"} {"pmid": "4216409", "title": "Other pathological processes in malaria.", "content": "Other pathological processes in malaria. Research since the World War II has confirmed that, apart from the production of haemozoin from haemoglobin, most of the pathological processes in the evolution of malaria are nonspecific. A few of these nonspecific host reactions are discussed, including the production of inflammatory stasis in certain areas (including the brain) where the vascular endothelium is normally highly impermeable to heavy molecules. This production of stasis is regarded as the basic phenomenon in local obstruction to blood flow. So-called \"plugging\" of small vessels with \"sticky\" infected erythrocytes is discussed in relation to stasis and to deep intravascular schizogony. Nonspecific vasomotor effects including shock and renal and hepatic failure are also discussed. Intravascular coagulation is not regarded as a potentially important host response despite demonstrable consumption coagulopathy. The disease malaria is regarded as an example of a chain reaction of physiological-pathological responses in the host, which in the early stages are reversible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216409"} {"pmid": "4216408", "title": "Immunopathology of malaria.", "content": "Immunopathology of malaria. Antibodies with different spectra of reactivity are produced during malarial infections and marked changes in IgG and IgM levels occur. In addition malaria elicits serological changes that are usually associated with connective tissue disease. The excessive anaemia associated with malaria may, in part, be an autoimmune phenomenon. Transient nephritis accompanies many plasmodial infections but chronic malarial nephrotic syndrome is specifically associated with quartan malaria. Malarial infection leads to splenomegaly, the most extreme form of which is idiopathic tropical splenomegaly, which probably represents an aberrant immune response to the infection. Malaria can affect the humoral immune response to unrelated antigens and infectious agents. This may be relevant to the etiology of Burkitt's lymphoma. During pregnancy there is some loss of acquired immunity to P. falciparum and the placenta appears to be an immunologically privileged site for the multiplication of this parasite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216408"} {"pmid": "4216410", "title": "The indirect haemagglutination test for malaria and its application to epidemiological surveillance.", "content": "The indirect haemagglutination test for malaria and its application to epidemiological surveillance. Recent studies with the indirect haemagglutination test for malaria are reviewed. Aspects of methodology, reproducibility, specificity, and sensitivity are discussed. A procedure is presented for application in the field, which indicates some progress towards developing a simple field method for the epidemiological surveillance of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216410"} {"pmid": "4216411", "title": "Prospects for vaccination against malaria in man.", "content": "Prospects for vaccination against malaria in man. Rodents have been successfully protected against a challenge of viable Plasmodium berghei by employing as vaccine: (1) the irradiated blood stages of the same parasite, or (2) the water-insoluble fraction of the blood stages, or (3) irradiated sporozoites; all these vaccines were shown to be stage-specific. A method is outlined for testing in the field, in the absence of any risks, the efficacy of analogous vaccines against falciparum malaria in man. It is emphasized that: (1) the efficacy of the vaccines can be tested in no model but only against P. falciparum in man; (2) the protection should be measured in terms of (a) prevention of morbidity, and (b) prevention of mortality; and (3) research must be intensified in order to meet, as needed, the requirements of mass production of merozoites and/or sporozoites, and to find ways to increase the human immune response to a higher level of protection against P. falciparum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216411"} {"pmid": "4216436", "title": "Extrinsic error in amniotic bilirubin determination for the prediction of antenatal hemolytic disease.", "content": "Extrinsic error in amniotic bilirubin determination for the prediction of antenatal hemolytic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216436"} {"pmid": "4216437", "title": "Studies of malformation syndromes in man. XXVII. The N syndrome, a \"new\" multiple congenital anomaly-mental retardation syndrome.", "content": "Studies of malformation syndromes in man. XXVII. The N syndrome, a \"new\" multiple congenital anomaly-mental retardation syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216437"} {"pmid": "4216438", "title": "Prenatal diagnosis: detailed chromosomal analysis in 500 cases.", "content": "Prenatal diagnosis: detailed chromosomal analysis in 500 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216438"} {"pmid": "4216439", "title": "Techniques in megavoltage radiotherapy. No. 5. Carcinoma of the bladder.", "content": "Techniques in megavoltage radiotherapy. No. 5. Carcinoma of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216439"} {"pmid": "4216440", "title": "Diverticulosis of the Fallopian tubes.", "content": "Diverticulosis of the Fallopian tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216440"} {"pmid": "4216441", "title": "Free radical production by metallic copper.", "content": "Free radical production by metallic copper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216441"} {"pmid": "4216442", "title": "Serum protein components in human endometrium.", "content": "Serum protein components in human endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216442"} {"pmid": "4216443", "title": "Bilateral vas ligation: sperm antibodies.", "content": "Bilateral vas ligation: sperm antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216443"} {"pmid": "4216445", "title": "Effect of oxytetracycline on the growth curve of Rickettsia prowazekii in the organism of the body louse (Pediculus humanus corporis L.) and Ornithodoros moubata tick (Murray).", "content": "Effect of oxytetracycline on the growth curve of Rickettsia prowazekii in the organism of the body louse (Pediculus humanus corporis L.) and Ornithodoros moubata tick (Murray).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216445"} {"pmid": "4216444", "title": "Effects of postovulatory norethindrone and estrogens on the plasma levels of estrogen and progesterone in rhesus monkeys.", "content": "Effects of postovulatory norethindrone and estrogens on the plasma levels of estrogen and progesterone in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216444"} {"pmid": "4216448", "title": "RNA synthesis in Drosophila melanogaster polytene chromosomes. Indications of simultaneous dosage compensation and dosage effect in X chromosomes.", "content": "RNA synthesis in Drosophila melanogaster polytene chromosomes. Indications of simultaneous dosage compensation and dosage effect in X chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216448"} {"pmid": "4216452", "title": "Neurophysin in rat posterior pituitary after ether anesthesia: disc electrophoresis, immunodiffusion and histology of hypothalamic nuclei.", "content": "Neurophysin in rat posterior pituitary after ether anesthesia: disc electrophoresis, immunodiffusion and histology of hypothalamic nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216452"} {"pmid": "4216453", "title": "Polyol metabolism in monkey-kidney epithelial-cell cultures. Sorbitol synthesis.", "content": "Polyol metabolism in monkey-kidney epithelial-cell cultures. Sorbitol synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216453"} {"pmid": "4216454", "title": "Primary structure of kappa light chain from a human myeloma protein.", "content": "Primary structure of kappa light chain from a human myeloma protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216454"} {"pmid": "4216455", "title": "Control of ornithine carbamoyltransferase activityby arginase in Bacillus subtilis.", "content": "Control of ornithine carbamoyltransferase activityby arginase in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216455"} {"pmid": "4216456", "title": "Introduction to the discussion on characteristics of installations for radiotherapy with fast neutrons and other types of high-LET radiation.", "content": "Introduction to the discussion on characteristics of installations for radiotherapy with fast neutrons and other types of high-LET radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216456"} {"pmid": "4216457", "title": "Characteristics of 252Cf neutron sources used for radiotherapy.", "content": "Characteristics of 252Cf neutron sources used for radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216457"} {"pmid": "4216458", "title": "Radiobiology with heavy charged particles directed at radiotherapy.", "content": "Radiobiology with heavy charged particles directed at radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216458"} {"pmid": "4216460", "title": "Review of RBE values of 15 MeV neutrons for effects on normal tissues.", "content": "Review of RBE values of 15 MeV neutrons for effects on normal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216460"} {"pmid": "4216459", "title": "Negative pions in radiotherapy: a brief review.", "content": "Negative pions in radiotherapy: a brief review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216459"} {"pmid": "4216461", "title": "The RBE of cyclotron neutrons for effects on normal tissues.", "content": "The RBE of cyclotron neutrons for effects on normal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216461"} {"pmid": "4216462", "title": "Repair and repopulation in mouse skin during fractionated neutron and x-irradiation.", "content": "Repair and repopulation in mouse skin during fractionated neutron and x-irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216462"} {"pmid": "4216463", "title": "Production of 14 MeV neutrons by a mixed deuterium-tritium beam.", "content": "Production of 14 MeV neutrons by a mixed deuterium-tritium beam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216463"} {"pmid": "4216464", "title": "A D-T neutron source with rotating target for radiotherapeutic applications.", "content": "A D-T neutron source with rotating target for radiotherapeutic applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216464"} {"pmid": "4216465", "title": "Neutron-therapy facility at the Radiotherapy Department of the University Hospital, Hamburg-Eppendorf.", "content": "Neutron-therapy facility at the Radiotherapy Department of the University Hospital, Hamburg-Eppendorf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216465"} {"pmid": "4216466", "title": "The \"Hiletron\" neutron generator at Manchester.", "content": "The \"Hiletron\" neutron generator at Manchester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216466"} {"pmid": "4216467", "title": "Recirculating gas target source for neutron cancer therapy.", "content": "Recirculating gas target source for neutron cancer therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216467"} {"pmid": "4216468", "title": "9-Be(d,n)10-B reaction for radiotherapeutic applications at the cyclotron in Rossendorf.", "content": "9-Be(d,n)10-B reaction for radiotherapeutic applications at the cyclotron in Rossendorf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216468"} {"pmid": "4216469", "title": "The MANTA neutron-therapy facility at the Naval Research Laboratory.", "content": "The MANTA neutron-therapy facility at the Naval Research Laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216469"} {"pmid": "4216470", "title": "Fast neutron beams from the MSKCC cyclotron.", "content": "Fast neutron beams from the MSKCC cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216470"} {"pmid": "4216471", "title": "The 7-Li(p,n)7-Be reaction as a useful source of fast neutrons for therapy.", "content": "The 7-Li(p,n)7-Be reaction as a useful source of fast neutrons for therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216471"} {"pmid": "4216472", "title": "Preliminary study of the neutron beam from 70 MeV deuterons on thick beryllium at the University of Maryland cyclotron.", "content": "Preliminary study of the neutron beam from 70 MeV deuterons on thick beryllium at the University of Maryland cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216472"} {"pmid": "4216473", "title": "A fast neutron beam facility at the cyclotron of the University of Louvain.", "content": "A fast neutron beam facility at the cyclotron of the University of Louvain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216473"} {"pmid": "4216474", "title": "Neutron therapy application at the Heidelberg cyclotron facility.", "content": "Neutron therapy application at the Heidelberg cyclotron facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216474"} {"pmid": "4216475", "title": "The fast neutron beam radiotherapy installation at the TAMVEC cyclotron.", "content": "The fast neutron beam radiotherapy installation at the TAMVEC cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216475"} {"pmid": "4216476", "title": "A medical cyclotron program in the National Institute of Radiological Sciences (NIRS), Japan.", "content": "A medical cyclotron program in the National Institute of Radiological Sciences (NIRS), Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216476"} {"pmid": "4216477", "title": "The University of Washington fast neutron beam therapy facility.", "content": "The University of Washington fast neutron beam therapy facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216477"} {"pmid": "4216478", "title": "Stanford University Hospital negative pi-meson beam radiotherapy program.", "content": "Stanford University Hospital negative pi-meson beam radiotherapy program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216478"} {"pmid": "4216479", "title": "Possible pion sources for radiotherapy.", "content": "Possible pion sources for radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216479"} {"pmid": "4216480", "title": "The negative pi-meson biomedical facility at TRIUMF.", "content": "The negative pi-meson biomedical facility at TRIUMF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216480"} {"pmid": "4216481", "title": "Characteristics of tumour responses to different radiations and the relative biological effectiveness of fast neutrons.", "content": "Characteristics of tumour responses to different radiations and the relative biological effectiveness of fast neutrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216481"} {"pmid": "4216482", "title": "On the relative importance of hypoxic cells for the radiotherapy of human tumours.", "content": "On the relative importance of hypoxic cells for the radiotherapy of human tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216482"} {"pmid": "4216483", "title": "Comparison of RBE values of 15 MeV neutrons for damage to an experimental tumour and some normal tissues.", "content": "Comparison of RBE values of 15 MeV neutrons for damage to an experimental tumour and some normal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216483"} {"pmid": "4216484", "title": "RBE values of 15 MeV neutrons applied at low dose rates.", "content": "RBE values of 15 MeV neutrons applied at low dose rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216484"} {"pmid": "4216485", "title": "Dosimetry of 9be (d, n) 10b neutrons for radiotherapeutic applications at the cyclotron in Rossendorf.", "content": "Dosimetry of 9be (d, n) 10b neutrons for radiotherapeutic applications at the cyclotron in Rossendorf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216485"} {"pmid": "4216486", "title": "The fast neutron beams from the TAMVEC cyclotron.", "content": "The fast neutron beams from the TAMVEC cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216486"} {"pmid": "4216487", "title": "Neutron dosimetry for the MANTA facility at NRL.", "content": "Neutron dosimetry for the MANTA facility at NRL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216487"} {"pmid": "4216488", "title": "Fast neutron beam dosimetry: comparison of the ion chamber and proportional counter approaches.", "content": "Fast neutron beam dosimetry: comparison of the ion chamber and proportional counter approaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216488"} {"pmid": "4216490", "title": "Dosimetry of D-T neutrons for radiotherapeutic applications at Rijswijk.", "content": "Dosimetry of D-T neutrons for radiotherapeutic applications at Rijswijk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216490"} {"pmid": "4216489", "title": "Energy distribution and depth doses of D-T neutrons in a tissue-equivalent phantom by activation threshold detectors.", "content": "Energy distribution and depth doses of D-T neutrons in a tissue-equivalent phantom by activation threshold detectors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216489"} {"pmid": "4216491", "title": "Neutron dosimetry system for routine treatment control.", "content": "Neutron dosimetry system for routine treatment control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216491"} {"pmid": "4216492", "title": "Neutron dosimetry in Manchester.", "content": "Neutron dosimetry in Manchester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216492"} {"pmid": "4216493", "title": "Neutron energy spectra in a phantom for the Hamburg and Heidelberg therapy units.", "content": "Neutron energy spectra in a phantom for the Hamburg and Heidelberg therapy units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216493"} {"pmid": "4216494", "title": "Dosimetry of fast neutrons for radiotherapy at the DKFZ cyclotron in Heidelberg.", "content": "Dosimetry of fast neutrons for radiotherapy at the DKFZ cyclotron in Heidelberg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216494"} {"pmid": "4216496", "title": "Preliminary dose measurements in the fast neutron beam at the cyclotron of the University of Louvain.", "content": "Preliminary dose measurements in the fast neutron beam at the cyclotron of the University of Louvain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216496"} {"pmid": "4216497", "title": "Neutron dose distributions and RBE.", "content": "Neutron dose distributions and RBE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216497"} {"pmid": "4216495", "title": "Dosimetry for D-T neutrons at Glasgow.", "content": "Dosimetry for D-T neutrons at Glasgow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216495"} {"pmid": "4216498", "title": "Collimation of a 14 MeV neutron beam.", "content": "Collimation of a 14 MeV neutron beam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216498"} {"pmid": "4216499", "title": "Calculation of depth dose and beam profile for the fast neutron beam produced by the Heidelberg cyclotron.", "content": "Calculation of depth dose and beam profile for the fast neutron beam produced by the Heidelberg cyclotron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216499"} {"pmid": "4216501", "title": "Some aspects in neutron shielding and collimation.", "content": "Some aspects in neutron shielding and collimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216501"} {"pmid": "4216500", "title": "Contribution of patient scatter to 15 MeV neutron beam penumbra.", "content": "Contribution of patient scatter to 15 MeV neutron beam penumbra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216500"} {"pmid": "4216502", "title": "Experimental studies in the collimation of 14-8 MeV neutrons.", "content": "Experimental studies in the collimation of 14-8 MeV neutrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216502"} {"pmid": "4216503", "title": "Dosimetry for neutron radiotherapy.", "content": "Dosimetry for neutron radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216503"} {"pmid": "4216505", "title": "Developments in achieving optimum beam profiles for 15 MeV neutron beams.", "content": "Developments in achieving optimum beam profiles for 15 MeV neutron beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216505"} {"pmid": "4216504", "title": "Depth dose characteristics and beam profile properties of cyclotron-produced neutron beams.", "content": "Depth dose characteristics and beam profile properties of cyclotron-produced neutron beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216504"} {"pmid": "4216511", "title": "Protein synthesis of monkey lung subcellular fractions after exposure to silica in vivo.", "content": "Protein synthesis of monkey lung subcellular fractions after exposure to silica in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216511"} {"pmid": "4216512", "title": "Endosymbiotic microorganisms in Cletus signatus Walker (Coreidae: Heteroptera).", "content": "Endosymbiotic microorganisms in Cletus signatus Walker (Coreidae: Heteroptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216512"} {"pmid": "4216514", "title": "The release of proteins and 5S RNA during the unfolding of Escherichia coli ribosomes.", "content": "The release of proteins and 5S RNA during the unfolding of Escherichia coli ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216514"} {"pmid": "4216513", "title": "Medicaid coverage of abortions in New York City: costs and benefits.", "content": "Medicaid coverage of abortions in New York City: costs and benefits. New York was among the first states to provide Medicaid financing of abortions for needy women. This was begun in July 1970 when the liberalized state abortion law took effect. Each year since, nearly 40% of the New York City abortion patients have been funded by Medicaid. There is evidence that Medicaid funding of abortions for indigent women has had a favorable impact on improving the health and welfare of these women. There are attempts nationwide to cut off or restrict Medicaid financing for abortions. Results of a cutback on funding will be 1) many septic and incomplete illegal abortions, 2) an increase of 10,000-15,000 births in New York City, and 3) added costs to federal, state, and local relief funds for delivery services, foster care, welfare payments, and day care facilities for these added births. Additional costs to government health and welfare organizations in the first year would be from 7-10 times what Medicaid coverage of abortions would cost.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216513"} {"pmid": "4216515", "title": "Purification and properties of tyrosinase inhibitor from mushroom.", "content": "Purification and properties of tyrosinase inhibitor from mushroom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216515"} {"pmid": "4216516", "title": "Delta pH and membrane potential in bacterial chromatophores.", "content": "Delta pH and membrane potential in bacterial chromatophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216516"} {"pmid": "4216518", "title": "Medicaid in Delaware.", "content": "Medicaid in Delaware.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216518"} {"pmid": "4216506", "title": "Low dose tolerance preventing tumor immunity.", "content": "Low dose tolerance preventing tumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216506"} {"pmid": "4216520", "title": "Ontogenesis of Ca++ and Mg++ contents of embryonic chick heart.", "content": "Ontogenesis of Ca++ and Mg++ contents of embryonic chick heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216520"} {"pmid": "4216521", "title": "Failure of synthetic TRF to elicit metamorphosis in frog tadpoles or red-spotted newts.", "content": "Failure of synthetic TRF to elicit metamorphosis in frog tadpoles or red-spotted newts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216521"} {"pmid": "4216522", "title": "Some observations on the study of the genetic control of meiosis in Drosophila melanogaster.", "content": "Some observations on the study of the genetic control of meiosis in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216522"} {"pmid": "4216523", "title": "Mechanisms of chromosomal and gene inactivation in Drosophila.", "content": "Mechanisms of chromosomal and gene inactivation in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216523"} {"pmid": "4216524", "title": "Long term success with homograft reconstruction of the aorta for the cure of aneurysm.", "content": "Long term success with homograft reconstruction of the aorta for the cure of aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216524"} {"pmid": "4216525", "title": "The measurement of renal function in children: a review.", "content": "The measurement of renal function in children: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216525"} {"pmid": "4216527", "title": "Autoradiographic and cytophotometric investigations on blast cells from acute leukaemia.", "content": "Autoradiographic and cytophotometric investigations on blast cells from acute leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216527"} {"pmid": "4216528", "title": "Phytohemagglutinin-stimulated rat lymphocytes and spleen-colony formation.", "content": "Phytohemagglutinin-stimulated rat lymphocytes and spleen-colony formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216528"} {"pmid": "4216529", "title": "The influence of prostaglandins E1 and E2 on platelet aggregation in mammals.", "content": "The influence of prostaglandins E1 and E2 on platelet aggregation in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216529"} {"pmid": "4216534", "title": "Biological abnormalities in erythroblasts and erythrocytes of acquired idiopathic dyserythropoietic anemia.", "content": "Biological abnormalities in erythroblasts and erythrocytes of acquired idiopathic dyserythropoietic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216534"} {"pmid": "4216539", "title": "On the alkaloids of Fumaria parviflora Lam.", "content": "On the alkaloids of Fumaria parviflora Lam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216539"} {"pmid": "4216540", "title": "On the diagnostical value of the white phenomenon's reaction and Black's reaction in malignant diseases.", "content": "On the diagnostical value of the white phenomenon's reaction and Black's reaction in malignant diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216540"} {"pmid": "4216541", "title": "Study on the antimycotic action of some essential oils obtained from local and introduced plants species.", "content": "Study on the antimycotic action of some essential oils obtained from local and introduced plants species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216541"} {"pmid": "4216542", "title": "Gaseous and acid-base changes in patients with cirrhosis hepatis in 100% oxygen respiration.", "content": "Gaseous and acid-base changes in patients with cirrhosis hepatis in 100% oxygen respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216542"} {"pmid": "4216543", "title": "Changes in foetal electrocardiograms in oxytocin stimulated birth.", "content": "Changes in foetal electrocardiograms in oxytocin stimulated birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216543"} {"pmid": "4216544", "title": "Uroinfection and antibiotic activity by calculous pyelonephritis.", "content": "Uroinfection and antibiotic activity by calculous pyelonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216544"} {"pmid": "4216545", "title": "Changes in the concentrations of the water soluble proteins and the activities of the lactic dehydrogenase, glutamic oxalacetic and glutamic-peruvic transaminases in m. gastrocnemius of a rat at various stages after crushing the innervating nerve (reinnervation).", "content": "Changes in the concentrations of the water soluble proteins and the activities of the lactic dehydrogenase, glutamic oxalacetic and glutamic-peruvic transaminases in m. gastrocnemius of a rat at various stages after crushing the innervating nerve (reinnervation).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216545"} {"pmid": "4216546", "title": "Differences in the histomorphologic and histochemical structure of the so called \"progressive\" and \"stationary\" pterygium.", "content": "Differences in the histomorphologic and histochemical structure of the so called \"progressive\" and \"stationary\" pterygium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216546"} {"pmid": "4216547", "title": "Electronomicroscopic morphometric changes the liver cell of rats following administration of alcohol and alcohol-reserpin.", "content": "Electronomicroscopic morphometric changes the liver cell of rats following administration of alcohol and alcohol-reserpin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216547"} {"pmid": "4216548", "title": "The effect of the constant magnetic field upon the growth and development of Tr vaginalis.", "content": "The effect of the constant magnetic field upon the growth and development of Tr vaginalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216548"} {"pmid": "4216549", "title": "The influence of the ionised air upon the development of Trichomonas vaginalis in cultures.", "content": "The influence of the ionised air upon the development of Trichomonas vaginalis in cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216549"} {"pmid": "4216551", "title": "Studies on the incidence of some infrabacterial pneumonias (viral-ricketsial and mycoplasmic) in Plovdiv during the period 1969-1971.", "content": "Studies on the incidence of some infrabacterial pneumonias (viral-ricketsial and mycoplasmic) in Plovdiv during the period 1969-1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216551"} {"pmid": "4216550", "title": "On the antimycotic effect of the Mericleri salt.", "content": "On the antimycotic effect of the Mericleri salt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216550"} {"pmid": "4216552", "title": "Comparison of the indices of the bromsulphalein test, the serum cholinesterase and the galactose test by hepatic cirrhosis.", "content": "Comparison of the indices of the bromsulphalein test, the serum cholinesterase and the galactose test by hepatic cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216552"} {"pmid": "4216553", "title": "On the diagnostical value of the indocyane clearance in chronic deseases of the liver.", "content": "On the diagnostical value of the indocyane clearance in chronic deseases of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216553"} {"pmid": "4216554", "title": "Types of vaginal cytosmears in late pregnancy and their prognostic value.", "content": "Types of vaginal cytosmears in late pregnancy and their prognostic value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216554"} {"pmid": "4216555", "title": "Preparing of labelled with 113m In ferric hydroxyde for scintigraphic examination of the lung.", "content": "Preparing of labelled with 113m In ferric hydroxyde for scintigraphic examination of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216555"} {"pmid": "4216556", "title": "A study upon the incidence and typal composition of the fungi Candida sp. in cases of mixed invasion with Tr. vaginalis by vaginal deseases.", "content": "A study upon the incidence and typal composition of the fungi Candida sp. in cases of mixed invasion with Tr. vaginalis by vaginal deseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216556"} {"pmid": "4216557", "title": "In support of the principle of metorysis.", "content": "In support of the principle of metorysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216557"} {"pmid": "4216559", "title": "Gastro-intestinal absorption and toxicology: ingesta-exchange and simulated-meal techniques.", "content": "Gastro-intestinal absorption and toxicology: ingesta-exchange and simulated-meal techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216559"} {"pmid": "4216561", "title": "Syndromes of Sturge-Weber and Klippel-Weber in the same patient.", "content": "Syndromes of Sturge-Weber and Klippel-Weber in the same patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216561"} {"pmid": "4216562", "title": "The stature of offspring and the assortative mating of parents.", "content": "The stature of offspring and the assortative mating of parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216562"} {"pmid": "4216563", "title": "A relationship between plasma cholesterol level, latitude, and the Rhesus blood group system.", "content": "A relationship between plasma cholesterol level, latitude, and the Rhesus blood group system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216563"} {"pmid": "4216564", "title": "Metric trends of the anterior teeth in African monkeys.", "content": "Metric trends of the anterior teeth in African monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216564"} {"pmid": "4216566", "title": "Is health care a right? Negative response.", "content": "Is health care a right? Negative response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216566"} {"pmid": "4216565", "title": "Molecular mechanism of glucose-6-phosphate dehydrogenase deficiency.", "content": "Molecular mechanism of glucose-6-phosphate dehydrogenase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216565"} {"pmid": "4216567", "title": "Immunological studies in tropical eosinophilia.", "content": "Immunological studies in tropical eosinophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216567"} {"pmid": "4216569", "title": "Circulatory immunoglobulin levels after an oral killed typhoid vaccination.", "content": "Circulatory immunoglobulin levels after an oral killed typhoid vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216569"} {"pmid": "4216568", "title": "Histoplasmin sensitivity survey.", "content": "Histoplasmin sensitivity survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216568"} {"pmid": "4216570", "title": "Degree of acetonaemia following epinephrine infusion to determine biochemical characterization of diabetes mellitus.", "content": "Degree of acetonaemia following epinephrine infusion to determine biochemical characterization of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216570"} {"pmid": "4216571", "title": "Factors influencing natural immunization in diphtheria in urban and rural communities in West Bengal.", "content": "Factors influencing natural immunization in diphtheria in urban and rural communities in West Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216571"} {"pmid": "4216572", "title": "Bacteriophage typing of hospital strains of Pseudomonas aeruginosa.", "content": "Bacteriophage typing of hospital strains of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216572"} {"pmid": "4216573", "title": "Evaluation of gel diffusion precipitin test for amoebiasis.", "content": "Evaluation of gel diffusion precipitin test for amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216573"} {"pmid": "4216574", "title": "Listeria meningitis in Delhi (a pilot study).", "content": "Listeria meningitis in Delhi (a pilot study).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216574"} {"pmid": "4216575", "title": "Reduction of drug resistance of mycobacterium tuberculosis after treatment with hamycin.", "content": "Reduction of drug resistance of mycobacterium tuberculosis after treatment with hamycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216575"} {"pmid": "4216576", "title": "Studies on freeze dried smallpox vaccine as a source of antigen in the precipitation-in-gel test.", "content": "Studies on freeze dried smallpox vaccine as a source of antigen in the precipitation-in-gel test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216576"} {"pmid": "4216577", "title": "Australia antigen in cirrhosis of childhood.", "content": "Australia antigen in cirrhosis of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216577"} {"pmid": "4216578", "title": "Bacterial response to combination of tetracycline and gentamicin.", "content": "Bacterial response to combination of tetracycline and gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216578"} {"pmid": "4216579", "title": "Prevalence of Brucella agglutinins in sera received for serological test for syphilis and Widal test.", "content": "Prevalence of Brucella agglutinins in sera received for serological test for syphilis and Widal test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216579"} {"pmid": "4216580", "title": "Diphtheria carriers among school chidren in Poona.", "content": "Diphtheria carriers among school chidren in Poona.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216580"} {"pmid": "4216581", "title": "Letter: Raised intra cranial tension due to rapid brain growth.", "content": "Letter: Raised intra cranial tension due to rapid brain growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216581"} {"pmid": "4216582", "title": "Screening for PKU of preschool children and newborn infants in Hyderabad.", "content": "Screening for PKU of preschool children and newborn infants in Hyderabad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216582"} {"pmid": "4216583", "title": "Blood free alpha amino nitrogen in hypoproteinemia.", "content": "Blood free alpha amino nitrogen in hypoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216583"} {"pmid": "4216587", "title": "Metabolic problems during mechanical ventilation of newborn infants.", "content": "Metabolic problems during mechanical ventilation of newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216587"} {"pmid": "4216588", "title": "Increased response of anoxic Bacillus megaterium spores to radiation at high dose-rates.", "content": "Increased response of anoxic Bacillus megaterium spores to radiation at high dose-rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216588"} {"pmid": "4216590", "title": "Diagnosis of rubella virus infection. II. The usefulness of sucrose density gradient centrifugation and indirect fluorescent antibody staining to demonstrate rubella IgG antibodies.", "content": "Diagnosis of rubella virus infection. II. The usefulness of sucrose density gradient centrifugation and indirect fluorescent antibody staining to demonstrate rubella IgG antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216590"} {"pmid": "4216593", "title": "Synthesis of bacteriophage phi DNA in toluenized preparations of Bacillus subtilis infected cells.", "content": "Synthesis of bacteriophage phi DNA in toluenized preparations of Bacillus subtilis infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216593"} {"pmid": "4216596", "title": "Australia antigen in viral hepatitis and hepatic cirrhosis.", "content": "Australia antigen in viral hepatitis and hepatic cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216596"} {"pmid": "4216597", "title": "An angiomatous malformation of brain with unusual clinical manifestations.", "content": "An angiomatous malformation of brain with unusual clinical manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216597"} {"pmid": "4216598", "title": "Folates in human serum.", "content": "Folates in human serum. Constituent serum folates have been shown to be altered and in some cases raised in diseases in which total folate levels are known to be frequently decreased. Absorption experiments showed that orally administered folate analogues affect the folate pool in different ways. The stability of the 10-formyltetrahydrofolate level in normal subjects is demonstrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216598"} {"pmid": "4216599", "title": "Culture of specimens other than sputum for Mycobacteria.", "content": "Culture of specimens other than sputum for Mycobacteria. A comparison has been made of Lowenstein-Jensen medium, with or without added pyruvate, 7H11 oleic acid-albumin agar slopes made selective by the addition of antibiotics, and selective Kirchner medium in the isolation of tubercle bacilli from specimens other than sputum. A combination of a standard mild preliminary treatment with sulphuric acid and selective medium reduced the contamination rate to 0.1%. Neither acid treatment nor antibiotics appeared to reduce the isolation rate. An effective procedure is to treat all specimens (except cerebrospinal fluid) with acid and culture on two Lowenstein-Jensen slopes (one with pyruvate), a 7H11 selective slope, and in two bottles of selective Kirchner medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216599"} {"pmid": "4216592", "title": "Proceedings: Recent researches on sphingolipidoses.", "content": "Proceedings: Recent researches on sphingolipidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216592"} {"pmid": "4216589", "title": "Renovascular hypertension in neurofibromatosis.", "content": "Renovascular hypertension in neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216589"} {"pmid": "4216600", "title": "Comparison of the titres of ASO, anti-DNase B, and antibodies against the group polysaccharide of group A streptococci in children with streptococcal infections.", "content": "Comparison of the titres of ASO, anti-DNase B, and antibodies against the group polysaccharide of group A streptococci in children with streptococcal infections. Antibodies against the group polysaccharide of group A streptococci were estimated by means of a haemagglutination reaction. In this reaction human erythrocytes of blood group O were sensitized with polysaccharide esterified with myristoylchloride. The optimal conditions of the reactions were determined by varying the ester group content in the antigen and the amount of ester used for sensitization. The specificity of the reaction could be established by reacting sensitized erythrocytes with homologous and heterologous sera and by absorption experiments. Antistreptococcal group A polysaccharide titres (ASPAT) and antibody levels to streptolysine O and DNase-B were compared in a group of 52 children with proved streptococcal infection and in 52 age- and season-matched controls. Antibody levels were significantly higher in the patient group than in the controls. In the ASPAT there was clearly less overlap between patients and controls than in both other reactions. In the patient group the ASO titres were raised above normal in 27 cases (51.9%), anti-DNase-B titres in 18 (34.6%), and ASPAT in 40 (76.9%). Taken together the three reactions gave a positive score in 51 cases (98.1%) in the patient group against 17 cases (32.7%) in the controls. A positive antibody response is usually defined as a rise of two dilution increments between the acute and convalescent sera. According to this definition the ASPAT showed a response in 42%, ASO and/or DNase-B in 42%, and the three reactions taken together in 68% of paired sera from patients. It is believed the ASPAT will prove a welcome addition to the diagnostic outfit when the presence of streptococcal infection in children is considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216600"} {"pmid": "4216601", "title": "Sterilization of the biological safety cabinet.", "content": "Sterilization of the biological safety cabinet. Test strips comprising B subtilis spores or M phlei cells dried on aluminium foil (some serum-coated) were used to test sterilizing processes currently advised for safety cabinets. Exposure to formalin from a bowl, boiling excess formalin with the fan running, and ultraviolet radiation were all found to be unreliable, as was glutaraldehyde. Vaporization of 2 ml of formalin per 0.028 m(3) followed by exposure for 18 hours at ambient temperatures was 100% successful, and the depolymerization of paraformaldehyde tablets with a hair drier was a simple, very effective alternative method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216601"} {"pmid": "4216591", "title": "Immunological identity between seminal plasma ribonuclease (BS-1) and seminal vesicle ribonuclease (SV-1).", "content": "Immunological identity between seminal plasma ribonuclease (BS-1) and seminal vesicle ribonuclease (SV-1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216591"} {"pmid": "4216602", "title": "Proceedings: The freeze-etching approach to the study of islet pathophysiology in diabetes.", "content": "Proceedings: The freeze-etching approach to the study of islet pathophysiology in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216602"} {"pmid": "4216604", "title": "Mycoplasmacidal activity of bovine milk for T-mycoplasmas.", "content": "Mycoplasmacidal activity of bovine milk for T-mycoplasmas. Normal bovine milk and whey was mycoplasmacidal for 6 of the 13 strains of bovine T-mycoplasmas examined. The in vitro assay used also demonstrated no killing of the human, canine and simian T-mycoplasma strains after 4 hr. incubation. However, there appeared to be some cow-to-cow variation in possession of this activity, and following E. coli endotoxin stimulation of the mammary gland the activity was considerably reduced.Whey from three normal cows was fractionated on a Bio-Gel A 1.5 m. column and the mycoplasmacidal activity of the resulting five peaks assayed. Only the second peak, peak B, contained activity and was characterized as the only peak containing bovine IgA. The active component in whey, however, was found to be heat stable at 60 degrees C. for 60 minutes and to pass through a dialysis membrane. This is inconsistent with it being immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216604"} {"pmid": "4216603", "title": "A simplified method for the detection of rubella-specific IgM employing sucrose density fractionation and 2-mercaptoethanol.", "content": "A simplified method for the detection of rubella-specific IgM employing sucrose density fractionation and 2-mercaptoethanol. A simplified method for the detection of rubella-specific IgM in sera was developed involving HAI tests on only one fraction from a sucrose density gradient with and without treatment with 2-mercaptoethanol (2 ME). Slight trailing of IgG into the IgM fraction was shown to occur in patients with high titres of both IgG and IgM, but this could be detected by the 2ME treatment and did not affect the results.By this test, rubella-specific IgM was found in all of 54 patients with a rash and a rise of rubella HAI antibodies. When the antigen and serum were incubated for 1 hr. before adding the RBC, specific IgM was found in all 51 sera taken between 5 and 40 days after onset, and in about half the sera taken between 42 and 77 days, but in none of 16 people known to have possessed rubella antibodies at least a year previously. When antigen and serum were incubated for 18 hr. before adding the RBC, specific IgM was found in all of 21 sera taken between 2 and 49 days after onset, and in 6 of 11 sera taken between 50 and 117 days, but not in 9 people known to have possessed rubella antibodies at least a year before. The method has been found to be very useful in detecting recent rubella among patients in early pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216603"} {"pmid": "4216606", "title": "Clinical evaluation of practolol in the treatment of angina pectoris.", "content": "Clinical evaluation of practolol in the treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216606"} {"pmid": "4216605", "title": "The survival and growth of Bacillus cereus in boiled and fried rice in relation to outbreaks of food poisoning.", "content": "The survival and growth of Bacillus cereus in boiled and fried rice in relation to outbreaks of food poisoning. A number of outbreaks of food poisoning attributed to Bacillus cereus have been reported recently and all have been associated with cooked rice usually from Chinese restaurants and ;take-away' shops.Tests were made to assess the heat resistance of B. cereus spores in aqueous suspension, the growth of the organism in boiled rice stored at temperatures in the range 4-55 degrees C., and the effect of cooking and storage on the growth of the organism in boiled and fried rice. The spores of B. cereus survived cooking and were capable of germination and outgrowth. The optimum temperature for growth in boiled rice was between 30 degrees and 37 degrees C. and growth also occurred during storage at 15 degrees and 43 degrees C.To prevent further outbreaks it is suggested that rice should be boiled in smaller quantities on several occasions during the day, thereby reducing the storage time before frying. After boiling the rice should either be kept hot (> 63 degrees C.) or cooled quickly and transferred to a refrigerator within 2 hr. of cooking. Boiled or fried rice must not be stored under warm conditions especially in the range 15-50 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216605"} {"pmid": "4216607", "title": "Biology and pathogenicity of the microsporidian Perezia hyperae sp. n., a pathogen of the alfalfa weevil, Hypera postica.", "content": "Biology and pathogenicity of the microsporidian Perezia hyperae sp. n., a pathogen of the alfalfa weevil, Hypera postica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216607"} {"pmid": "4216608", "title": "Shell mats associated with microsporida in Biomphalaria glabrata: genetic studies.", "content": "Shell mats associated with microsporida in Biomphalaria glabrata: genetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216608"} {"pmid": "4216610", "title": "Treatment of gonorrhea with cefazolin plus probenecid.", "content": "Treatment of gonorrhea with cefazolin plus probenecid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216610"} {"pmid": "4216609", "title": "The antibacterial efficiencies of ovine IgA, IgM, and IgG.", "content": "The antibacterial efficiencies of ovine IgA, IgM, and IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216609"} {"pmid": "4216615", "title": "Guidelines for total parenteral nutrition.", "content": "Guidelines for total parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216615"} {"pmid": "4216616", "title": "Letter: ATP content in erythrocytes of Plasmodium knowlesi-infected monkeys.", "content": "Letter: ATP content in erythrocytes of Plasmodium knowlesi-infected monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216616"} {"pmid": "4216617", "title": "Proceedings: Inhibition of hypothalamic unit activity by iontophoretically applied luteinizing hormone releasing factor and thyrotrophin releasing factor.", "content": "Proceedings: Inhibition of hypothalamic unit activity by iontophoretically applied luteinizing hormone releasing factor and thyrotrophin releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216617"} {"pmid": "4216618", "title": "Calcitonin given intragastrally and resistance to histamine-induced peptic ulcer in guinea-pigs.", "content": "Calcitonin given intragastrally and resistance to histamine-induced peptic ulcer in guinea-pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216618"} {"pmid": "4216619", "title": "Proceedings: The relationship between prolactin and gonadotrophins: effects of clomiphene administration in normal men.", "content": "Proceedings: The relationship between prolactin and gonadotrophins: effects of clomiphene administration in normal men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216619"} {"pmid": "4216620", "title": "Proceedings: Effect on prolactin secretion of thyrotrophin releasing factor.", "content": "Proceedings: Effect on prolactin secretion of thyrotrophin releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216620"} {"pmid": "4216621", "title": "Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides.", "content": "Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216621"} {"pmid": "4216622", "title": "A study of biogenic amine metabolites in the cerebrospinal fluid and urine of monkeys with chlorpromazine-induced dyskinesia.", "content": "A study of biogenic amine metabolites in the cerebrospinal fluid and urine of monkeys with chlorpromazine-induced dyskinesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216622"} {"pmid": "4216623", "title": "Heterogeneity of the glial fibrillary acidic protein in gliosed human brains.", "content": "Heterogeneity of the glial fibrillary acidic protein in gliosed human brains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216623"} {"pmid": "4216624", "title": "Treatment of congenital chylothorax.", "content": "Treatment of congenital chylothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216624"} {"pmid": "4216625", "title": "Solitary neonatal hepatic abscess.", "content": "Solitary neonatal hepatic abscess. A solitary hepatic abscess was found at postmortem examination in a neonate who died at 25 days of age. Elevation of the right diaphragm was noted radiologically from the first day of life, suggesting congenital presence of the abscess. Recognition of the previously unsuspected association between hepatic abscess and congenital diaphragmatic elevation might have led to surgical intervention and have increased the infant's chance of survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216625"} {"pmid": "4216626", "title": "Detection of endotoxemia with the Limulus test: preliminary studies in severely malnourished children.", "content": "Detection of endotoxemia with the Limulus test: preliminary studies in severely malnourished children. Eighteen Peruvian children with protein-calorie malnutrition were studied to evaluate the usefulness of the limulus assay for endotoxin in detecting gram-negative sepsis. Nine of the children had at least one positive Limulus assay, and eight of this group had bacteriologic cultures indicative of gram-negative infection. Four of these nine children with positive Limulus assays died, whereas only one of the nine children with negative assays died. This preliminary study suggests the usefulness of the Limulus assay as an adjunct to bacteriologic cultures in the early detection of significant gram-negative infection in severely malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216626"} {"pmid": "4216627", "title": "Intracellular sodium and potassium concentrations in toad and frog oocytes during development.", "content": "Intracellular sodium and potassium concentrations in toad and frog oocytes during development. 1. During growth of oocytes of Bufo bufo from approximately 700-2000 mum in diameter, intracellular Na rose from 20 to 120 m-mole/l. cell water while K fell from 120 to 15 m-mole/l. cell water.2. In Rana temporaria Na similarly rose from 9 to 190 m-mole/l. cell water and K fell from 126 to 28 m-mole/l. cell water.3. At the same time in both Bufo and Rana the ouabain-sensitive Na efflux, the ouabain-insensitive Na efflux, and the total Na influx all increased.4. It is concluded that the predominant process is an increase of passive Na permeability. The increase of apparently active Na efflux may be secondary to the consequent rise in intracellular Na.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216627"} {"pmid": "4216628", "title": "Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation.", "content": "Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation. 1. During the first phase of maturation in oocytes of Bufo bufo, after the growth phase but before ovulation, intracellular Na rises to 120 m-mole/l. cell water while K falls to 15 m-mole/l. cell water.2. At the same time, the ouabain-insensitive Na efflux and total Na influx both increase while the ouabain-sensitive Na efflux is unchanged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216628"} {"pmid": "4216629", "title": "Proceedings: The response of neurones in the pre-central cortex to an unexpected disturbance of finger position.", "content": "Proceedings: The response of neurones in the pre-central cortex to an unexpected disturbance of finger position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216629"} {"pmid": "4216632", "title": "The St. Kitts vervet (Cercopithecus aethiops).", "content": "The St. Kitts vervet (Cercopithecus aethiops).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216632"} {"pmid": "4216631", "title": "Normal T cell population in chronic lymphocytic leukemia: analysis of phytohemagglutinin dose-response curves.", "content": "Normal T cell population in chronic lymphocytic leukemia: analysis of phytohemagglutinin dose-response curves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216631"} {"pmid": "4216633", "title": "BCG immunization in marmosets.", "content": "BCG immunization in marmosets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216633"} {"pmid": "4216637", "title": "Recurrent radial nerve palsy.", "content": "Recurrent radial nerve palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216637"} {"pmid": "4216635", "title": "Interrelationship of H+ excretion and Na+ reabsorption in the toad urinary bladder.", "content": "Interrelationship of H+ excretion and Na+ reabsorption in the toad urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216635"} {"pmid": "4216634", "title": "Pathways for movement of ions and water across toad urinary bladder. II. Site and mode of action of vasopressin.", "content": "Pathways for movement of ions and water across toad urinary bladder. II. Site and mode of action of vasopressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216634"} {"pmid": "4216636", "title": "Effect of fixatives on fracture plane in red blood cells.", "content": "Effect of fixatives on fracture plane in red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216636"} {"pmid": "4216638", "title": "Structure of a dimeric fragment related to the lambda-type Bence-Jones protein: a preliminary study.", "content": "Structure of a dimeric fragment related to the lambda-type Bence-Jones protein: a preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216638"} {"pmid": "4216639", "title": "Protein-protein proximity in the association of ribosomal subunits of Escherichia coli: crosslinking of 30 S protein S16 to 50 S proteins by glutaraldehyde or formaldehyde.", "content": "Protein-protein proximity in the association of ribosomal subunits of Escherichia coli: crosslinking of 30 S protein S16 to 50 S proteins by glutaraldehyde or formaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216639"} {"pmid": "4216640", "title": "Strjcture of human plasma prealbumin at 2-5 A resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding.", "content": "Strjcture of human plasma prealbumin at 2-5 A resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216640"} {"pmid": "4216641", "title": "Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse.", "content": "Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216641"} {"pmid": "4216643", "title": "Membrane-bound polyribosomes in HeLa cells: association of polyadenylic acid with membranes.", "content": "Membrane-bound polyribosomes in HeLa cells: association of polyadenylic acid with membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216643"} {"pmid": "4216655", "title": "New Japanese variant of human erythrocyte carbonic anhydrase.", "content": "New Japanese variant of human erythrocyte carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216655"} {"pmid": "4216656", "title": "Serologic relationship of coxsackie A-16 viruses from the epidemic of hand-foot-and mouth disease in Japan, 1970, to the prototype strain.", "content": "Serologic relationship of coxsackie A-16 viruses from the epidemic of hand-foot-and mouth disease in Japan, 1970, to the prototype strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216656"} {"pmid": "4216686", "title": "[Bedside nursing: Nursing of a patient with Buerger's disease associated with persistent pain].", "content": "[Bedside nursing: Nursing of a patient with Buerger's disease associated with persistent pain].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216686"} {"pmid": "4216720", "title": "Long-term therapy of hereditary angioedema (HAE). Preventive management with fluoxymesterone and oxymetholone in severely affected males and females.", "content": "Long-term therapy of hereditary angioedema (HAE). Preventive management with fluoxymesterone and oxymetholone in severely affected males and females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216720"} {"pmid": "4216723", "title": "Absence of antinatriferic and natriuretic activity in plasma ultrafiltrates (mol wt less than 50,000) and dialysates from volume-expanded dogs.", "content": "Absence of antinatriferic and natriuretic activity in plasma ultrafiltrates (mol wt less than 50,000) and dialysates from volume-expanded dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216723"} {"pmid": "4216728", "title": "Convenient micro system for double diffusion immuno precipitin tests.", "content": "Convenient micro system for double diffusion immuno precipitin tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216728"} {"pmid": "4216730", "title": "Current practice with vitamin K antagonist therapy.", "content": "Current practice with vitamin K antagonist therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216730"} {"pmid": "4216735", "title": "The use of anti-human haemoglobin in forensic serology.", "content": "The use of anti-human haemoglobin in forensic serology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216735"} {"pmid": "4216737", "title": "The action of pure phospholipases on native and ghost red cell membranes.", "content": "The action of pure phospholipases on native and ghost red cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216737"} {"pmid": "4216739", "title": "Isolation of spectrin from erythrocyte membranes.", "content": "Isolation of spectrin from erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216739"} {"pmid": "4216738", "title": "Phospholipase C (phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) from Bacillus cereus.", "content": "Phospholipase C (phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) from Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216738"} {"pmid": "4216740", "title": "Cell adhesion.", "content": "Cell adhesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216740"} {"pmid": "4216729", "title": "Activity of some lysosomal enzymes in Hurler's syndrome (type i mucopolysaccharidosis).", "content": "Activity of some lysosomal enzymes in Hurler's syndrome (type i mucopolysaccharidosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216729"} {"pmid": "4216741", "title": "Cell layer assay.", "content": "Cell layer assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216741"} {"pmid": "4216742", "title": "Cations, antibiotics, and membranes.", "content": "Cations, antibiotics, and membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216742"} {"pmid": "4216747", "title": "The photometric titration of Fe(III) with EDTA using Tiron indicator.", "content": "The photometric titration of Fe(III) with EDTA using Tiron indicator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216747"} {"pmid": "4216748", "title": "The use of substituted hydrazones as metallochromic indicators: the EDTA titration of copper.", "content": "The use of substituted hydrazones as metallochromic indicators: the EDTA titration of copper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216748"} {"pmid": "4216756", "title": "A comparison by gel diffusion of the Lancefield and Rantz extraction techniques used in grouping haemolytic streptococci.", "content": "A comparison by gel diffusion of the Lancefield and Rantz extraction techniques used in grouping haemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216756"} {"pmid": "4216757", "title": "An assessment of an automated immunoprecipitin technique for the measurement of immunoglobulins G, A and M.", "content": "An assessment of an automated immunoprecipitin technique for the measurement of immunoglobulins G, A and M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216757"} {"pmid": "4216758", "title": "Physico-chemical characterisation of rinderpest virus.", "content": "Physico-chemical characterisation of rinderpest virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216758"} {"pmid": "4216759", "title": "Defective interfering particles produced during the replication of measles virus.", "content": "Defective interfering particles produced during the replication of measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216759"} {"pmid": "4216760", "title": "SSPE measles virus: non-productive and productive infection in Vero cells and suckling mice.", "content": "SSPE measles virus: non-productive and productive infection in Vero cells and suckling mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216760"} {"pmid": "4216761", "title": "Variants of measles virus.", "content": "Variants of measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216761"} {"pmid": "4216763", "title": "Restriction and modification in Bacillus subtilis. Induction of a modifying activity in Bacillus subtilis 168.", "content": "Restriction and modification in Bacillus subtilis. Induction of a modifying activity in Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216763"} {"pmid": "4216765", "title": "Genetic instability in Drosophila melanogaster. A mutable tandem duplication.", "content": "Genetic instability in Drosophila melanogaster. A mutable tandem duplication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216765"} {"pmid": "4216764", "title": "Genetic instability in Drosophila melanogaster. Evidence for insertion mutations.", "content": "Genetic instability in Drosophila melanogaster. Evidence for insertion mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216764"} {"pmid": "4216766", "title": "Establishment of a correlation between physical molecule and genetic map in one segment of the SPP1 chromosome.", "content": "Establishment of a correlation between physical molecule and genetic map in one segment of the SPP1 chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216766"} {"pmid": "4216767", "title": "The ribosomal proteins of Drosophila melanogaster. Localization of stage specific proteins on the small and large ribosomal subunit.", "content": "The ribosomal proteins of Drosophila melanogaster. Localization of stage specific proteins on the small and large ribosomal subunit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216767"} {"pmid": "4216768", "title": "Mutual regulation of magnified bobbed loci in Drosophila melanogaster.", "content": "Mutual regulation of magnified bobbed loci in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216768"} {"pmid": "4216769", "title": "UV-sensitivity and UV-mutability of infectious lambdaDNA: reactivation, protection and mutability in various assay systems.", "content": "UV-sensitivity and UV-mutability of infectious lambdaDNA: reactivation, protection and mutability in various assay systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216769"} {"pmid": "4216770", "title": "Tetanus toxin conformation.", "content": "Tetanus toxin conformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216770"} {"pmid": "4216854", "title": "The survival of microfungi in the nests of tree-sparrow (Passer montanus L.) in the nest-boxes over the winter season.", "content": "The survival of microfungi in the nests of tree-sparrow (Passer montanus L.) in the nest-boxes over the winter season.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216854"} {"pmid": "4216856", "title": "Glyoxalase system enzyme activity in the liver of rats fed dimethylaminoazobenzene.", "content": "Glyoxalase system enzyme activity in the liver of rats fed dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216856"} {"pmid": "4216857", "title": "Monoclonal IgG-kappa cryoimmunoglobulin in a woman patient with lymphoreticular series hemoblastosis.", "content": "Monoclonal IgG-kappa cryoimmunoglobulin in a woman patient with lymphoreticular series hemoblastosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216857"} {"pmid": "4216859", "title": "Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices.", "content": "Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216859"} {"pmid": "4216860", "title": "Language and brain: developmental aspects.", "content": "Language and brain: developmental aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216860"} {"pmid": "4216862", "title": "Medicaid prepayment: concept and implementation.", "content": "Medicaid prepayment: concept and implementation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216862"} {"pmid": "4216861", "title": "Symptomatic ossification of the posterior longitudinal ligament of the cervical spine. Clinical findings.", "content": "Symptomatic ossification of the posterior longitudinal ligament of the cervical spine. Clinical findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216861"} {"pmid": "4216864", "title": "Regional health authorities.", "content": "Regional health authorities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216864"} {"pmid": "4216866", "title": "Factors in the causation and incidence of ovarian cancer.", "content": "Factors in the causation and incidence of ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216866"} {"pmid": "4216865", "title": "The performance of an anti D immunoprophylaxis scheme.", "content": "The performance of an anti D immunoprophylaxis scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216865"} {"pmid": "4216867", "title": "Estriol in pregnancy.", "content": "Estriol in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216867"} {"pmid": "4216868", "title": "Human prolactin: secretion, regulation and pathophysiology.", "content": "Human prolactin: secretion, regulation and pathophysiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216868"} {"pmid": "4216869", "title": "Tyrosinase activity of aqueous humour in uveal melanoblastoma.", "content": "Tyrosinase activity of aqueous humour in uveal melanoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216869"} {"pmid": "4216870", "title": "Reaction of the exposed pulp to Dycal treatment.", "content": "Reaction of the exposed pulp to Dycal treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216870"} {"pmid": "4216874", "title": "Total body potassium estimations in young children: the interpretation of results.", "content": "Total body potassium estimations in young children: the interpretation of results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216874"} {"pmid": "4216875", "title": "Distribution of PCB and p,p'-DDE residues in Atlantic herring (Clupea harengus harengus) and yellow perch (Perca flavescens) in Eastern Canada--1972.", "content": "Distribution of PCB and p,p'-DDE residues in Atlantic herring (Clupea harengus harengus) and yellow perch (Perca flavescens) in Eastern Canada--1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216875"} {"pmid": "4216877", "title": "Pesticide residue levels in soils and crops, FY-70--national soils monitoring program (II).", "content": "Pesticide residue levels in soils and crops, FY-70--national soils monitoring program (II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216877"} {"pmid": "4216876", "title": "Residues of the insecticide mirex in terrestrial and aquatic invertebrates following a single aerial application of mirex bait, Louisiana--1971-72.", "content": "Residues of the insecticide mirex in terrestrial and aquatic invertebrates following a single aerial application of mirex bait, Louisiana--1971-72.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216876"} {"pmid": "4216890", "title": "I-cell disease--mucolipidosis II.", "content": "I-cell disease--mucolipidosis II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216890"} {"pmid": "4216892", "title": "Some problems in cancer management. The Michael Williams Lecture 1974.", "content": "Some problems in cancer management. The Michael Williams Lecture 1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216892"} {"pmid": "4216895", "title": "Isolation of higher molecular weight DNA from Bacillus Cereus T using proteinase K.", "content": "Isolation of higher molecular weight DNA from Bacillus Cereus T using proteinase K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216895"} {"pmid": "4216896", "title": "Isolation and characterization of a temperature sensitive protein from dog colostrum and milk.", "content": "Isolation and characterization of a temperature sensitive protein from dog colostrum and milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216896"} {"pmid": "4216900", "title": "Effect of androgens on the red cell 2, 3 diphosphoglycerate hemoglobin oxygen affinity and red cell mass in mammals.", "content": "Effect of androgens on the red cell 2, 3 diphosphoglycerate hemoglobin oxygen affinity and red cell mass in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216900"} {"pmid": "4216901", "title": "Virulence measurements of Pseudomonas aeruginosa based on plaque and toxin Z formation in cell culture.", "content": "Virulence measurements of Pseudomonas aeruginosa based on plaque and toxin Z formation in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216901"} {"pmid": "4216902", "title": "Effect of the H37Ra strain of M. tuberculosis and of a mycobacterial RNA fraction on tumor growth.", "content": "Effect of the H37Ra strain of M. tuberculosis and of a mycobacterial RNA fraction on tumor growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216902"} {"pmid": "4216903", "title": "The study of shea butter. 4. Stability of medicaments in shea butter ointments and creams.", "content": "The study of shea butter. 4. Stability of medicaments in shea butter ointments and creams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216903"} {"pmid": "4216904", "title": "The action of ergot alkaloids (ergotamine and dihydroergotoxin) on the functional effects of cerebral ischemia in the cat.", "content": "The action of ergot alkaloids (ergotamine and dihydroergotoxin) on the functional effects of cerebral ischemia in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216904"} {"pmid": "4216905", "title": "The psychiatrist attitudes and therapeutic means when faced with resistant depressions.", "content": "The psychiatrist attitudes and therapeutic means when faced with resistant depressions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216905"} {"pmid": "4216908", "title": "A standard system of coordinates for radiotherapy apparatus. HPA Radiotherapy Physics Topic Group.", "content": "A standard system of coordinates for radiotherapy apparatus. HPA Radiotherapy Physics Topic Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216908"} {"pmid": "4216907", "title": "A theoretical evaluation of plastic dosimetry phantoms.", "content": "A theoretical evaluation of plastic dosimetry phantoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216907"} {"pmid": "4216909", "title": "The application of the logarithmic response of silicon diodes to monitoring beam symmetry and electron energy.", "content": "The application of the logarithmic response of silicon diodes to monitoring beam symmetry and electron energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216909"} {"pmid": "4216910", "title": "Limitations of the use of the geometric mean to obtain depth independence in scanning and whole body counting.", "content": "Limitations of the use of the geometric mean to obtain depth independence in scanning and whole body counting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216910"} {"pmid": "4216912", "title": "Pion dose calculations suitable for treatment planning.", "content": "Pion dose calculations suitable for treatment planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216912"} {"pmid": "4216911", "title": "Heavy particles in therapy: an application of track theory.", "content": "Heavy particles in therapy: an application of track theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216911"} {"pmid": "4216913", "title": "Energy calibration of high energy electrons using a Cerenkov detector and a comparison with different methods.", "content": "Energy calibration of high energy electrons using a Cerenkov detector and a comparison with different methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216913"} {"pmid": "4216914", "title": "Spectral dependence of the FeSO4 G-value in DT neutron beams.", "content": "Spectral dependence of the FeSO4 G-value in DT neutron beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216914"} {"pmid": "4216915", "title": "Excited states and photobiological properties of potential DNA cross-linking agents, the benzodipyrones.", "content": "Excited states and photobiological properties of potential DNA cross-linking agents, the benzodipyrones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216915"} {"pmid": "4216926", "title": "The hypothalamus and behavioral patterns.", "content": "The hypothalamus and behavioral patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216926"} {"pmid": "4216925", "title": "An observational study of hallucinogen-induced behavior in unrestrained Macaca mulatta.", "content": "An observational study of hallucinogen-induced behavior in unrestrained Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216925"} {"pmid": "4216927", "title": "Structure and fiber connections of the hypothalamus in mammals.", "content": "Structure and fiber connections of the hypothalamus in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216927"} {"pmid": "4216928", "title": "Parenteral nutrition.", "content": "Parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216928"} {"pmid": "4216929", "title": "Techniques of total intravenous feeding. A comment to the paper by F. Jarrett.", "content": "Techniques of total intravenous feeding. A comment to the paper by F. Jarrett.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216929"} {"pmid": "4216938", "title": "Protection of microsomal drug biotransformation enzymes against carbon tetrachloride by diethyldithiocarbamate in rat liver.", "content": "Protection of microsomal drug biotransformation enzymes against carbon tetrachloride by diethyldithiocarbamate in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216938"} {"pmid": "4216939", "title": "Theileria lawrencei infection of cattle and African buffalo: evaluation of a buffalo cell culture schizont antigen for the indirect fluorescent antibody test.", "content": "Theileria lawrencei infection of cattle and African buffalo: evaluation of a buffalo cell culture schizont antigen for the indirect fluorescent antibody test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216939"} {"pmid": "4216940", "title": "Immunogenicity of mycoplasma galactan.", "content": "Immunogenicity of mycoplasma galactan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216940"} {"pmid": "4216959", "title": "The economic approach to family health studies.", "content": "The economic approach to family health studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216959"} {"pmid": "4216958", "title": "Experiences with a new test of exocrine pancreatic function in protein deficient Patas monkeys.", "content": "Experiences with a new test of exocrine pancreatic function in protein deficient Patas monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216958"} {"pmid": "4216960", "title": "The causes of the disappearance and reappearance of induced sublethal mutations in Drosophila melanogaster in the course of a number of generations.", "content": "The causes of the disappearance and reappearance of induced sublethal mutations in Drosophila melanogaster in the course of a number of generations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216960"} {"pmid": "4216961", "title": "An anatomical study of the pineal body of the vervet monkey (Cercopithecus aethiops).", "content": "An anatomical study of the pineal body of the vervet monkey (Cercopithecus aethiops).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216961"} {"pmid": "4216962", "title": "A histochemical study of the pineal body of the vervet monkey (Cercopithecus aethiops).", "content": "A histochemical study of the pineal body of the vervet monkey (Cercopithecus aethiops).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216962"} {"pmid": "4216963", "title": "Aflatoxin and primary liver cancer.", "content": "Aflatoxin and primary liver cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216963"} {"pmid": "4216964", "title": "Letter: Effect of measles on the intra-epithelial lymphocyte count of malnourished children.", "content": "Letter: Effect of measles on the intra-epithelial lymphocyte count of malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216964"} {"pmid": "4216965", "title": "Incidence and spectrum of malnutrition in paediatric hospital wards.", "content": "Incidence and spectrum of malnutrition in paediatric hospital wards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216965"} {"pmid": "4216968", "title": "The treatment of advanced cancer by fast neutrons from the Medical Research Council's cyclotron at Hammersmith Hospital, London.", "content": "The treatment of advanced cancer by fast neutrons from the Medical Research Council's cyclotron at Hammersmith Hospital, London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216968"} {"pmid": "4216969", "title": "RBE values of 15 MeV neutrons for responses of pulmonary metastases in patients.", "content": "RBE values of 15 MeV neutrons for responses of pulmonary metastases in patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216969"} {"pmid": "4216970", "title": "Clinical features of 16 and 50 Mev d leads to Be neutrons.", "content": "Clinical features of 16 and 50 Mev d leads to Be neutrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216970"} {"pmid": "4216971", "title": "Comparison between neutron therapy and 60Co gamma ray therapy of bronchial, gastric and oesophagus carcinomata.", "content": "Comparison between neutron therapy and 60Co gamma ray therapy of bronchial, gastric and oesophagus carcinomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216971"} {"pmid": "4216972", "title": "The use of californium-252 sources for brachytherapy of human tumours: a preliminary report.", "content": "The use of californium-252 sources for brachytherapy of human tumours: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216972"} {"pmid": "4216973", "title": "Evaluation of 252Cf neutron emitter for intersitital and intracavitary radiation therapy.", "content": "Evaluation of 252Cf neutron emitter for intersitital and intracavitary radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216973"} {"pmid": "4216974", "title": "Clinical trials with fast neutrons.", "content": "Clinical trials with fast neutrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216974"} {"pmid": "4216975", "title": "Registration of clinical data and criteria for selection of patients for fast neutron trials.", "content": "Registration of clinical data and criteria for selection of patients for fast neutron trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216975"} {"pmid": "4216976", "title": "International cooperation with regard to clinical trials of fast neutron radiotherapy.", "content": "International cooperation with regard to clinical trials of fast neutron radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216976"} {"pmid": "4216977", "title": "The Wisconsin Society of Radiation Oncologists' fast neutron treatment facility.", "content": "The Wisconsin Society of Radiation Oncologists' fast neutron treatment facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216977"} {"pmid": "4216979", "title": "Plans for neutron radiotherapy in the radiotherapy department of the University Hospital Hamburg-Eppendorf.", "content": "Plans for neutron radiotherapy in the radiotherapy department of the University Hospital Hamburg-Eppendorf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216979"} {"pmid": "4216978", "title": "Plans for the high-energy, heavy-ion facility (BEVALAC) at Berkeley.", "content": "Plans for the high-energy, heavy-ion facility (BEVALAC) at Berkeley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216978"} {"pmid": "4216980", "title": "Studies of the proteins elutable from certain artificial surfaces exposed to human plasma.", "content": "Studies of the proteins elutable from certain artificial surfaces exposed to human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216980"} {"pmid": "4216985", "title": "Variation of RBE as a function of depth in a high energy electron beam in the first millimeters of the irradiated tissues determined by the observation of skin reactions on patients (a clinical trial).", "content": "Variation of RBE as a function of depth in a high energy electron beam in the first millimeters of the irradiated tissues determined by the observation of skin reactions on patients (a clinical trial).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216985"} {"pmid": "4216986", "title": "Skin tolerance in rabbits to alpha particle and low energy electron irradiation.", "content": "Skin tolerance in rabbits to alpha particle and low energy electron irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216986"} {"pmid": "4216987", "title": "Double-tracer method for determining the proteolytical activity of RES in X-irradiated rats using 131I-labelled albumin microspheres.", "content": "Double-tracer method for determining the proteolytical activity of RES in X-irradiated rats using 131I-labelled albumin microspheres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216987"} {"pmid": "4216997", "title": "Immunodiagnostic tests for bilharziasis. III. Serodiagnosis of Schistosoma haematobium. Infection and influence of chemotherapy on immunodiagnostic tests.", "content": "Immunodiagnostic tests for bilharziasis. III. Serodiagnosis of Schistosoma haematobium. Infection and influence of chemotherapy on immunodiagnostic tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216997"} {"pmid": "4216998", "title": "Cross-reacting antigens among some Filariae and other nematodes.", "content": "Cross-reacting antigens among some Filariae and other nematodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216998"} {"pmid": "4216999", "title": "Exoantigens of Trypanosoma cruzi in vivo.", "content": "Exoantigens of Trypanosoma cruzi in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4216999"} {"pmid": "4217003", "title": "Treatment of chronic cystitis by instillation: experiments employing an artificial model.", "content": "Treatment of chronic cystitis by instillation: experiments employing an artificial model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217003"} {"pmid": "4217016", "title": "Listeria monocytogenes type 5 as a cause of abortion in sheep.", "content": "Listeria monocytogenes type 5 as a cause of abortion in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217016"} {"pmid": "4217017", "title": "Bovine brucellosis in Nigeria.", "content": "Bovine brucellosis in Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217017"} {"pmid": "4217025", "title": "A standardized autopsy-protocol--problems and solutions.", "content": "A standardized autopsy-protocol--problems and solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217025"} {"pmid": "4217026", "title": "Cellular breakdown within the arterial wall. An ultrastructural study of the coronary artery in young and aging rats.", "content": "Cellular breakdown within the arterial wall. An ultrastructural study of the coronary artery in young and aging rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217026"} {"pmid": "4217028", "title": "Epithelial proliferation and morphogenesis of hyperplastic adenomatous and villous polyps of the human colon.", "content": "Epithelial proliferation and morphogenesis of hyperplastic adenomatous and villous polyps of the human colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217028"} {"pmid": "4217027", "title": "The influence of the autonomic nervous system on the ultrastructure of the parotid acinar cells. Experimental contribution to the neurohormonal sialadenosis.", "content": "The influence of the autonomic nervous system on the ultrastructure of the parotid acinar cells. Experimental contribution to the neurohormonal sialadenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217027"} {"pmid": "4217029", "title": "The pathology of pulmonary veno-occlusive disease.", "content": "The pathology of pulmonary veno-occlusive disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217029"} {"pmid": "4217030", "title": "Endodermal sinus tumor or orchioblastoma in children and adults.", "content": "Endodermal sinus tumor or orchioblastoma in children and adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217030"} {"pmid": "4217031", "title": "The structure of the glomerular capillary basement membrane in diabetes mellitus with and without nephrotic syndrome.", "content": "The structure of the glomerular capillary basement membrane in diabetes mellitus with and without nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217031"} {"pmid": "4217032", "title": "Scanning and transmission electron microscopy observations on the surface lining of aortic intimal plaques in rabbits on a hypercholesterolic diet.", "content": "Scanning and transmission electron microscopy observations on the surface lining of aortic intimal plaques in rabbits on a hypercholesterolic diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217032"} {"pmid": "4217033", "title": "Immune insulitis and manifest diabetes mellitus. Studies on the course of immune insulitis and the induction of diabetes mellitus in rabbits immunized with insulin.", "content": "Immune insulitis and manifest diabetes mellitus. Studies on the course of immune insulitis and the induction of diabetes mellitus in rabbits immunized with insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217033"} {"pmid": "4217035", "title": "Calibres of aorta and pulmonary artery in hypoplastic left and right heart syndromes: effects of abnormal bloodflow?", "content": "Calibres of aorta and pulmonary artery in hypoplastic left and right heart syndromes: effects of abnormal bloodflow?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217035"} {"pmid": "4217036", "title": "Immunofluorescence, histochemical and ultrastructural studies for the detection of multiple endocrine polypeptide tumours of the pancreas.", "content": "Immunofluorescence, histochemical and ultrastructural studies for the detection of multiple endocrine polypeptide tumours of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217036"} {"pmid": "4217038", "title": "Glomerular changes in acute renal allograft rejection in the dog.", "content": "Glomerular changes in acute renal allograft rejection in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217038"} {"pmid": "4217039", "title": "Specificity of inhibition of experimental autoallergic lesions of rat salivary glands.", "content": "Specificity of inhibition of experimental autoallergic lesions of rat salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217039"} {"pmid": "4217040", "title": "Demonstration of percellular channels in glamerular podocytes in aminonucleoside nephosis.", "content": "Demonstration of percellular channels in glamerular podocytes in aminonucleoside nephosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217040"} {"pmid": "4217041", "title": "The computation of lightness by the primate retina.", "content": "The computation of lightness by the primate retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217041"} {"pmid": "4217056", "title": "Strain tolerance of the vv. cerebri sup. (bridiging veins) calculated from head-on collision tests with cadavers.", "content": "Strain tolerance of the vv. cerebri sup. (bridiging veins) calculated from head-on collision tests with cadavers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217056"} {"pmid": "4217057", "title": "A cage for the successful maintenance of tree shrews (Tupaia belangeri) in captivity.", "content": "A cage for the successful maintenance of tree shrews (Tupaia belangeri) in captivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217057"} {"pmid": "4217060", "title": "Bovine congenital skeletal defects.", "content": "Bovine congenital skeletal defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217060"} {"pmid": "4217061", "title": "Congenital porta-caval shunts in the dog; a description of three cases.", "content": "Congenital porta-caval shunts in the dog; a description of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217061"} {"pmid": "4217063", "title": "Clinical and pathological observations on five cases of equine sarcoidosis identified in Romania.", "content": "Clinical and pathological observations on five cases of equine sarcoidosis identified in Romania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217063"} {"pmid": "4217064", "title": "Some aspects of the cardiovascular physiology of the duck.", "content": "Some aspects of the cardiovascular physiology of the duck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217064"} {"pmid": "4217067", "title": "Blood thiamine levels and transketolase activities as a diagnostic method for thiamine adequacy in cattle.", "content": "Blood thiamine levels and transketolase activities as a diagnostic method for thiamine adequacy in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217067"} {"pmid": "4217068", "title": "Proteic content of human uterine secretion.", "content": "Proteic content of human uterine secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217068"} {"pmid": "4217069", "title": "[Granulomatous cholesterol salpingitis with ceroid accumulation and osseous metaplasia].", "content": "[Granulomatous cholesterol salpingitis with ceroid accumulation and osseous metaplasia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217069"} {"pmid": "4217070", "title": "Myeloid cell actinomycin binding in human myeloid leukaemia.", "content": "Myeloid cell actinomycin binding in human myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217070"} {"pmid": "4217072", "title": "Abnormal factor X (factor X Friuli) coagulation disorder. The heterozygote population. A study of 57 subjects.", "content": "Abnormal factor X (factor X Friuli) coagulation disorder. The heterozygote population. A study of 57 subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217072"} {"pmid": "4217073", "title": "Hereditary elliptocytosis associated with pernicious anaemia.", "content": "Hereditary elliptocytosis associated with pernicious anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217073"} {"pmid": "4217075", "title": "Capacity of rat haemopoietic colony-forming units to produce differentiated progeny.", "content": "Capacity of rat haemopoietic colony-forming units to produce differentiated progeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217075"} {"pmid": "4217074", "title": "Purpura characterised by thrombasthenia associated with alterations of blood lipids.", "content": "Purpura characterised by thrombasthenia associated with alterations of blood lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217074"} {"pmid": "4217076", "title": "Distribution of colony-forming cells in mouse bone marrow.", "content": "Distribution of colony-forming cells in mouse bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217076"} {"pmid": "4217077", "title": "Concurrent infectious mononucleosis and acute myelocytic leukemia.", "content": "Concurrent infectious mononucleosis and acute myelocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217077"} {"pmid": "4217078", "title": "Rosette-forming lymphocytes in normals and patients with malignant lymphomas.", "content": "Rosette-forming lymphocytes in normals and patients with malignant lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217078"} {"pmid": "4217080", "title": "A study of lymphocytic beta-glucuronidase in various benign and malignant lymphatic processes.", "content": "A study of lymphocytic beta-glucuronidase in various benign and malignant lymphatic processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217080"} {"pmid": "4217079", "title": "PHA response of blood and lymph node lymphocytes in vitro in malignant lymphomas.", "content": "PHA response of blood and lymph node lymphocytes in vitro in malignant lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217079"} {"pmid": "4217081", "title": "Water, electrolytes, vitamins and carbohydrates in parenteral nutrition.", "content": "Water, electrolytes, vitamins and carbohydrates in parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217081"} {"pmid": "4217082", "title": "Hyperalimentation.", "content": "Hyperalimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217082"} {"pmid": "4217083", "title": "Therapy with fat emulsion.", "content": "Therapy with fat emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217083"} {"pmid": "4217085", "title": "Nutrition of medical patients.", "content": "Nutrition of medical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217085"} {"pmid": "4217084", "title": "Intravenous amino acid therapy.", "content": "Intravenous amino acid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217084"} {"pmid": "4217086", "title": "Parenteral nutrition in uremia.", "content": "Parenteral nutrition in uremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217086"} {"pmid": "4217088", "title": "Enzyme histochemical and ultrastructural alterations in the brains of Friesian calves with GM1 gangliosidosis.", "content": "Enzyme histochemical and ultrastructural alterations in the brains of Friesian calves with GM1 gangliosidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217088"} {"pmid": "4217090", "title": "The physiological effects of iron deficiency anaemia and malnutrition on exercise performance in East African school children.", "content": "The physiological effects of iron deficiency anaemia and malnutrition on exercise performance in East African school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217090"} {"pmid": "4217089", "title": "Studies on GM1-gangliosidosis, type II.", "content": "Studies on GM1-gangliosidosis, type II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217089"} {"pmid": "4217091", "title": "Multiple sclerosis--a critique and prospective.", "content": "Multiple sclerosis--a critique and prospective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217091"} {"pmid": "4217092", "title": "The background histories of schoolchildren severely malnourished in infancy.", "content": "The background histories of schoolchildren severely malnourished in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217092"} {"pmid": "4217093", "title": "Lactose malabsorption: its biology and history.", "content": "Lactose malabsorption: its biology and history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217093"} {"pmid": "4217094", "title": "Familial dysautonomia: diagnosis, pathogenesis and management.", "content": "Familial dysautonomia: diagnosis, pathogenesis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217094"} {"pmid": "4217095", "title": "Venereal disease in children.", "content": "Venereal disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217095"} {"pmid": "4217096", "title": "Standardisation of arthritogenic adjuvants for evaluating anti-inflammatory and immunosuppressant drugs.", "content": "Standardisation of arthritogenic adjuvants for evaluating anti-inflammatory and immunosuppressant drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217096"} {"pmid": "4217097", "title": "An improved fixation procedure for microtubules and microfilaments in cells of the anterior pituitary gland.", "content": "An improved fixation procedure for microtubules and microfilaments in cells of the anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217097"} {"pmid": "4217098", "title": "Patterns of protein-energy malnutrition in early childhood in Jordan.", "content": "Patterns of protein-energy malnutrition in early childhood in Jordan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217098"} {"pmid": "4217099", "title": "Significance of anaerobic spirochetes in the intestines of animals.", "content": "Significance of anaerobic spirochetes in the intestines of animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217099"} {"pmid": "4217100", "title": "Lactobacilli which attach to the crop epithelium of the fowl.", "content": "Lactobacilli which attach to the crop epithelium of the fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217100"} {"pmid": "4217101", "title": "Nutritional features and ecology of predominant anaerobic bacteria of the intestinal tract.", "content": "Nutritional features and ecology of predominant anaerobic bacteria of the intestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217101"} {"pmid": "4217102", "title": "Metabolic interactions among intestinal microorganisms.", "content": "Metabolic interactions among intestinal microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217102"} {"pmid": "4217103", "title": "Microbial bile acid transformation.", "content": "Microbial bile acid transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217103"} {"pmid": "4217104", "title": "Serologically active glycolipid families from Mycobacterium bovis BCG. II. Serologic studies on human sera.", "content": "Serologically active glycolipid families from Mycobacterium bovis BCG. II. Serologic studies on human sera. Serological tests with serologically active glycolipids from Mycobacterium bovis BCG were investigated for their possible use in the diagonis of mycobacterioses. The results were positive with 95 percent of sera from patients with far advanced and moderately advanced tuberculosis, 80 percent of sera from patients with newly diagnosed tuberculosis and 75 percent of patients with atypical mycobacterial diseases. \"False\" positive serologic reactions were obtained from 4 percent or less. Furthermore, 39 percent of sera from recent tuberculin converters were positive compared with only 9 percent of sera from unselected PPD positive individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217104"} {"pmid": "4217105", "title": "The human ultraviolet action spectrum.", "content": "The human ultraviolet action spectrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217105"} {"pmid": "4217106", "title": "Hemolytic anemia of premature infants associated with vitamin E deficiency. Animal model: hemolytic anemia in monkeys deficient in vitamin E.", "content": "Hemolytic anemia of premature infants associated with vitamin E deficiency. Animal model: hemolytic anemia in monkeys deficient in vitamin E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217106"} {"pmid": "4217121", "title": "The effect of practolol on circulatory response after sympathetic stimulation and on plasma growth hormone and insulin levels.", "content": "The effect of practolol on circulatory response after sympathetic stimulation and on plasma growth hormone and insulin levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217121"} {"pmid": "4217123", "title": "Treatment of partial ruptures of the lateral ligament of the ankle in acute ankle sprains.", "content": "Treatment of partial ruptures of the lateral ligament of the ankle in acute ankle sprains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217123"} {"pmid": "4217124", "title": "The surgical treatment of injuries of the fibular collateral ligaments of the ankle.", "content": "The surgical treatment of injuries of the fibular collateral ligaments of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217124"} {"pmid": "4217116", "title": "[Longitudinally bracketed diaphysis].", "content": "[Longitudinally bracketed diaphysis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217116"} {"pmid": "4217125", "title": "The mid-dermis graft - an experimental study.", "content": "The mid-dermis graft - an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217125"} {"pmid": "4217126", "title": "Vitamin B12 absorption after resection of ileum in childhood.", "content": "Vitamin B12 absorption after resection of ileum in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217126"} {"pmid": "4217127", "title": "Letter: effective thyroxine ratio in infants, children, and adolescents.", "content": "Letter: effective thyroxine ratio in infants, children, and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217127"} {"pmid": "4217118", "title": "[Heart diverticula in children: radiological aspects].", "content": "[Heart diverticula in children: radiological aspects].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217118"} {"pmid": "4217117", "title": "[The Laurence-Moon-Bardet-Biedl syndrome. Urographic signs].", "content": "[The Laurence-Moon-Bardet-Biedl syndrome. Urographic signs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217117"} {"pmid": "4217129", "title": "Blood group antigens and antibodies in Nigeria.", "content": "Blood group antigens and antibodies in Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217129"} {"pmid": "4217131", "title": "Iron supplementation in Thai fish-sauce.", "content": "Iron supplementation in Thai fish-sauce.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217131"} {"pmid": "4217130", "title": "Some further observations on the use of a continuous flow apparatus for the maintenance of schistosomes and blood protozoa in vitro.", "content": "Some further observations on the use of a continuous flow apparatus for the maintenance of schistosomes and blood protozoa in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217130"} {"pmid": "4217132", "title": "The effect of vasodilators on calcium kinetics in blood vessels.", "content": "The effect of vasodilators on calcium kinetics in blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217132"} {"pmid": "4217144", "title": "Photorespiration in diatoms. The oxidation of glycolic acid in Thallassiosira pseudonana (Cyclotella nana).", "content": "Photorespiration in diatoms. The oxidation of glycolic acid in Thallassiosira pseudonana (Cyclotella nana).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217144"} {"pmid": "4217145", "title": "The pigments of Flexibacter elegans: novel and chemosystematically useful compounds.", "content": "The pigments of Flexibacter elegans: novel and chemosystematically useful compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217145"} {"pmid": "4217149", "title": "The influence of pharmaca on the oxygen induced constriction of the human umbilical cord artery.", "content": "The influence of pharmaca on the oxygen induced constriction of the human umbilical cord artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217149"} {"pmid": "4217150", "title": "Phytohemagglutinin-induced blastoid transformation of lymphocytes, skin tests and immunoglobulin levels in clinically advanced malignant lymphogranulomatosis.", "content": "Phytohemagglutinin-induced blastoid transformation of lymphocytes, skin tests and immunoglobulin levels in clinically advanced malignant lymphogranulomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217150"} {"pmid": "4217155", "title": "Collagen fibre bundles of the normal marginal g-ngiva in the marmoset.", "content": "Collagen fibre bundles of the normal marginal g-ngiva in the marmoset.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217155"} {"pmid": "4217154", "title": "Influence of concentration, time, temperature and pH on the retention of chlorhexidine in the human oral cavity after mouth rinses.", "content": "Influence of concentration, time, temperature and pH on the retention of chlorhexidine in the human oral cavity after mouth rinses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217154"} {"pmid": "4217156", "title": "The use of amphotericin B to increase the selectivity of media used for isolating oral lactobacilli.", "content": "The use of amphotericin B to increase the selectivity of media used for isolating oral lactobacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217156"} {"pmid": "4217157", "title": "Collagen breakdown in relation to tooth eruption and resorption in the dog.", "content": "Collagen breakdown in relation to tooth eruption and resorption in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217157"} {"pmid": "4217162", "title": "Vestibular sensory epithelia.", "content": "Vestibular sensory epithelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217162"} {"pmid": "4217166", "title": "Some quantitative features of Drosophila sternite bristle patterns.", "content": "Some quantitative features of Drosophila sternite bristle patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217166"} {"pmid": "4217165", "title": "Effect of composition of tris-based diluent on survival of boar spermatozoa following deep freezing.", "content": "Effect of composition of tris-based diluent on survival of boar spermatozoa following deep freezing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217165"} {"pmid": "4217167", "title": "trypsin extractable precipitating antigens of Leptospira interrogans (serotype Biflexa).", "content": "trypsin extractable precipitating antigens of Leptospira interrogans (serotype Biflexa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217167"} {"pmid": "4217168", "title": "Relative specificities of immunoglobulins reacting with axial filament antigens of Leptospira.", "content": "Relative specificities of immunoglobulins reacting with axial filament antigens of Leptospira.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217168"} {"pmid": "4217169", "title": "The origin of antibody in intestinal secretion of sheep.", "content": "The origin of antibody in intestinal secretion of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217169"} {"pmid": "4217170", "title": "A microtitre serum neutralization test for bovine ephemeral fever virus.", "content": "A microtitre serum neutralization test for bovine ephemeral fever virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217170"} {"pmid": "4217173", "title": "Letter: Sarcoptes scabiei infestation of a koala (Phascolarctos cinereus), with probable human involvement.", "content": "Letter: Sarcoptes scabiei infestation of a koala (Phascolarctos cinereus), with probable human involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217173"} {"pmid": "4217171", "title": "Immunodeficiency and grouping with thyrogastric autoimmune disease in patients with chronic idiopathic thrombocytopenic purpura.", "content": "Immunodeficiency and grouping with thyrogastric autoimmune disease in patients with chronic idiopathic thrombocytopenic purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217171"} {"pmid": "4217172", "title": "Studies on equine herpesviruses. 5. Isolation and characterisation of slowly cytopathic equine herpesviruses in Queensland.", "content": "Studies on equine herpesviruses. 5. Isolation and characterisation of slowly cytopathic equine herpesviruses in Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217172"} {"pmid": "4217174", "title": "Vertebral angiography in bilateral VIII cranial nerve tumours. A report of a case.", "content": "Vertebral angiography in bilateral VIII cranial nerve tumours. A report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217174"} {"pmid": "4217176", "title": "Quantitative analysis of ciliary and contractile responses during habituation training in Spirostomum ambiguum.", "content": "Quantitative analysis of ciliary and contractile responses during habituation training in Spirostomum ambiguum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217176"} {"pmid": "4217175", "title": "The alteration of aversive thresholds after chronic administration of two tranquilizing agents.", "content": "The alteration of aversive thresholds after chronic administration of two tranquilizing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217175"} {"pmid": "4217177", "title": "Ultrastructure of genetic activity in eukaryotic cells.", "content": "Ultrastructure of genetic activity in eukaryotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217177"} {"pmid": "4217178", "title": "Radio telemetry of blood flow and pressure measurements in untethered conscious animals.", "content": "Radio telemetry of blood flow and pressure measurements in untethered conscious animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217178"} {"pmid": "4217179", "title": "A selective system for a biochemical analysis of the lethal mutation l(2)me of Drosophila melanogaster.", "content": "A selective system for a biochemical analysis of the lethal mutation l(2)me of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217179"} {"pmid": "4217180", "title": "Nucleotide sequence divergence among DNA fractions of different syngens of Tetrahymena pyriformis.", "content": "Nucleotide sequence divergence among DNA fractions of different syngens of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217180"} {"pmid": "4217181", "title": "The specificity of chain interactions among immunoglobulins. Combinations of gamma chains with kappa chains of the same subgroup as in the parent immunoglobulin G.", "content": "The specificity of chain interactions among immunoglobulins. Combinations of gamma chains with kappa chains of the same subgroup as in the parent immunoglobulin G. 1. The specificity of combination of heavy and light chains from selected human immunoglobulins was examined in the light of greater structural information than in previous studies. Heavy (gamma) chains from immunoglobulin G (kappa) myeloma proteins were allowed to combine with their homologous light (kappa) chains or with other kappa chains of the same variable-region subgroup. The affinity of each such pairing was assessed by having the test kappa chain compete with a standard population of normal light chains. 2. There was a spread of affinities among the heavy-light pairings with the homologous pairings having an average affinity significantly higher than the heterologous pairings. 3. It follows that (a) the preference shown for homologous heavy-light pairings is not explicable simply in terms of the known subdivisions of the variable and constant regions of the chains, and (b) it is unlikely that those residues specifying the subgroups of kappa-chain variable regions have a predominant role in the formation of interchain bonds with the gamma-chain variable regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217181"} {"pmid": "4217182", "title": "Analysis of the specific radioactivity of valine isolated from aminoacyl-transfer ribonucleic acid of rat liver.", "content": "Analysis of the specific radioactivity of valine isolated from aminoacyl-transfer ribonucleic acid of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217182"} {"pmid": "4217183", "title": "Disorders of lipid metabolism.", "content": "Disorders of lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217183"} {"pmid": "4217184", "title": "Effect of dietary changes on the rates of synthesis and degradation of rat liver fatty acid synthetase.", "content": "Effect of dietary changes on the rates of synthesis and degradation of rat liver fatty acid synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217184"} {"pmid": "4217185", "title": "Studies on the membranes of Bacilli. III. Disaggregation and reaggregation of the membrane components of Bacillus megaterium KM.", "content": "Studies on the membranes of Bacilli. III. Disaggregation and reaggregation of the membrane components of Bacillus megaterium KM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217185"} {"pmid": "4217187", "title": "Primary drug resistant tuberculosis in Puerto Rico.", "content": "Primary drug resistant tuberculosis in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217187"} {"pmid": "4217186", "title": "Sympathetic receptor functions in liver damage.", "content": "Sympathetic receptor functions in liver damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217186"} {"pmid": "4217193", "title": "Protection of mice against syngeneic lymphomata: I. Use of antibodies.", "content": "Protection of mice against syngeneic lymphomata: I. Use of antibodies. Protection tests using passively administered antibody have been carried out using 2 mouse lymphomata. The classic model (\"Gorer System\") used alloantiserum which was absorbed in vivo to make it tumour specific before use. In order to provide a system suitable for our work, the model was changed by stepwise transitions to tumour specific immunoglobulin made from xenoantiserum absorbed in vitro, since such a procedure is also applicable to human patients. The time lapse used between challenge and treatment in the allo-system was generally ± 2 h but in the xeno-system could be extended to + 18 h. The xenoantisera could not be absorbed in vivo but required 3 to 5 × 10(3) spleens per 100 ml serum to absorb in vitro to render them tumour specific. The protective antibody was in the IgG (not IgM) fraction of serum. Maximal tumour specific antibody (measured by in vivo protection) appeared after the third injection of rabbits for one lymphoma, but after the fifth for another. The sera were not cross-reactive among 3 lymphomata tested, of which 2 were of the same H-2 genotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217193"} {"pmid": "4217194", "title": "Protection of mice against syngeneic lymphomata: II. Collaboration between drugs and antibodies.", "content": "Protection of mice against syngeneic lymphomata: II. Collaboration between drugs and antibodies. Rabbit anti-mouse tumour cell serum can be made tumour specific by absorption with normal mouse cells and in an in vivo protection test can be shown to have a measurable protective effect on mice against a given number of lethal doses of a lymphoma. Some drugs have been evaluated in this system. When drug treatment is combined with antibody treatment much greater protection can be obtained than when the same amounts of drug or antibody are used alone. It is preferable to administer drug before antibody and with the combined schedule it is possible in the test model to protect all mice from tumour growth, even allowing the tumour up to 48 h \"get-away\" time before starting treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217194"} {"pmid": "4217205", "title": "The American perspective.", "content": "The American perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217205"} {"pmid": "4217207", "title": "Comparative assessment of microbiological methods for the diagnosis of gonorrhea in women.", "content": "Comparative assessment of microbiological methods for the diagnosis of gonorrhea in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217207"} {"pmid": "4217206", "title": "Acute and chronic biological false positive reactors to serological tests for syphilis. ABO blood groups and other investigations.", "content": "Acute and chronic biological false positive reactors to serological tests for syphilis. ABO blood groups and other investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217206"} {"pmid": "4217208", "title": "Treatment of gonorrhoea using a combination of intramuscular and oral ampicillin.", "content": "Treatment of gonorrhoea using a combination of intramuscular and oral ampicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217208"} {"pmid": "4217209", "title": "Comparison of direct microscopy and culture in the diagnosis of trichomoniasis.", "content": "Comparison of direct microscopy and culture in the diagnosis of trichomoniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217209"} {"pmid": "4217210", "title": "Primary syphilis in the oral cavity.", "content": "Primary syphilis in the oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217210"} {"pmid": "4217214", "title": "Inorganic pyrophosphatase in mineralizing hamster molars. IV. Modification of the inhibition of EDTA, diphosphonates and L-ascorbic acid by Zn2+ and C02+.", "content": "Inorganic pyrophosphatase in mineralizing hamster molars. IV. Modification of the inhibition of EDTA, diphosphonates and L-ascorbic acid by Zn2+ and C02+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217214"} {"pmid": "4217213", "title": "Effects of ethylenediaminetetraacetate (EDTA) on urinary excretion of hydroxyproline, calcium and phosphorus in the rat.", "content": "Effects of ethylenediaminetetraacetate (EDTA) on urinary excretion of hydroxyproline, calcium and phosphorus in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217213"} {"pmid": "4217215", "title": "Temperature-sensitive mutations in Drosophila melanogaster. XX. Lethality due to translocations.", "content": "Temperature-sensitive mutations in Drosophila melanogaster. XX. Lethality due to translocations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217215"} {"pmid": "4217204", "title": "Phencyclidine: pharmacology and toxicology.", "content": "Phencyclidine: pharmacology and toxicology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217204"} {"pmid": "4217218", "title": "Ultrastructural localization of calcium in the pigeon papillary muscle as demonstrated by cytochemical studies and x-ray microanalysis.", "content": "Ultrastructural localization of calcium in the pigeon papillary muscle as demonstrated by cytochemical studies and x-ray microanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217218"} {"pmid": "4217216", "title": "Is primary drug-resistance to major antituberculous agents increasing?", "content": "Is primary drug-resistance to major antituberculous agents increasing?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217216"} {"pmid": "4217217", "title": "A new antitumor agent, (alphas, 4s, 5r)-alpha-amino-3-chloro-4-hydroxy-4,5-dihydro-5-isoxazoleacetic acid (NSC-176324): preliminary evaluation against L 1210 mouse leukemia in vivo.", "content": "A new antitumor agent, (alphas, 4s, 5r)-alpha-amino-3-chloro-4-hydroxy-4,5-dihydro-5-isoxazoleacetic acid (NSC-176324): preliminary evaluation against L 1210 mouse leukemia in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217217"} {"pmid": "4217234", "title": "Fatal Bacillus cereus pneumonia and sepsis in a child with cancer.", "content": "Fatal Bacillus cereus pneumonia and sepsis in a child with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217234"} {"pmid": "4217235", "title": "Normal immunoglobulin levels in children who have recovered from meningococcal meningitis.", "content": "Normal immunoglobulin levels in children who have recovered from meningococcal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217235"} {"pmid": "4217236", "title": "Prepubescent gonococcal vulvovaginitis.", "content": "Prepubescent gonococcal vulvovaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217236"} {"pmid": "4217237", "title": "Vertebral osteomyelitis in a young infant.", "content": "Vertebral osteomyelitis in a young infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217237"} {"pmid": "4217238", "title": "Laboratory tests for the assessment of nutritional status.", "content": "Laboratory tests for the assessment of nutritional status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217238"} {"pmid": "4217239", "title": "Erwinia infections in man.", "content": "Erwinia infections in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217239"} {"pmid": "4217240", "title": "A double-blind evaluation of 'Hydergine' and placebo in the treatment of patients with organic brain syndrome and cerebral arteriosclerosis in a nursing home.", "content": "A double-blind evaluation of 'Hydergine' and placebo in the treatment of patients with organic brain syndrome and cerebral arteriosclerosis in a nursing home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217240"} {"pmid": "4217241", "title": "A comparison of the onset of bronchodilator activity of metaproterenol and isoproterenol aerosols.", "content": "A comparison of the onset of bronchodilator activity of metaproterenol and isoproterenol aerosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217241"} {"pmid": "4217242", "title": "\"Immunostaging\" as a guideline to immunotherapy in malignancy.", "content": "\"Immunostaging\" as a guideline to immunotherapy in malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217242"} {"pmid": "4217243", "title": "Prazosin in hypertension: a double-blind evaluation with methyldopa and placebo.", "content": "Prazosin in hypertension: a double-blind evaluation with methyldopa and placebo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217243"} {"pmid": "4217244", "title": "The effects of metolazone in the long-term treatment of essential hypertension.", "content": "The effects of metolazone in the long-term treatment of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217244"} {"pmid": "4217246", "title": "Local treatment of psoriasis and eczema with betamethasone-17,21-dipropionate (Diproderm cream): a double-blind comparsion with fluocortolone caproate, fluocortolone pivalate (Ultralanum cream).", "content": "Local treatment of psoriasis and eczema with betamethasone-17,21-dipropionate (Diproderm cream): a double-blind comparsion with fluocortolone caproate, fluocortolone pivalate (Ultralanum cream).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217246"} {"pmid": "4217245", "title": "Treatment of essential hypertension with pindolol and clopamide: problems arising from a combined beta blocker and diuretic therapy.", "content": "Treatment of essential hypertension with pindolol and clopamide: problems arising from a combined beta blocker and diuretic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217245"} {"pmid": "4217247", "title": "A double-blind comparison of a tetracycline-novobiocin combination antibiotic and tetracycline alone in common infections.", "content": "A double-blind comparison of a tetracycline-novobiocin combination antibiotic and tetracycline alone in common infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217247"} {"pmid": "4217248", "title": "Sulpiride: a chemotherapy for post-traumatic vertigo syndromes.", "content": "Sulpiride: a chemotherapy for post-traumatic vertigo syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217248"} {"pmid": "4217249", "title": "Double-blind comparison of alophen with its components for cathartic effects.", "content": "Double-blind comparison of alophen with its components for cathartic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217249"} {"pmid": "4217250", "title": "Viloxiazine--a new antidepressant.", "content": "Viloxiazine--a new antidepressant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217250"} {"pmid": "4217251", "title": "Loxapine succinate: a controlled double-blind study in schizophrenia.", "content": "Loxapine succinate: a controlled double-blind study in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217251"} {"pmid": "4217252", "title": "Assessment of antipsychotic activity of a butyrophenone analogue, lenperone (AHR 2277).", "content": "Assessment of antipsychotic activity of a butyrophenone analogue, lenperone (AHR 2277).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217252"} {"pmid": "4217253", "title": "Pilot open-label study on U-28,774, in anxious in-patients.", "content": "Pilot open-label study on U-28,774, in anxious in-patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217253"} {"pmid": "4217265", "title": "Development of the macronuclear anlage in the ciliate Chilodonella uncinate. I. Morphological and cytophotometric studies on the evolution of DNA.", "content": "Development of the macronuclear anlage in the ciliate Chilodonella uncinate. I. Morphological and cytophotometric studies on the evolution of DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217265"} {"pmid": "4217273", "title": "Thyroid function of the aged as viewed from the pituitary-thyroid system.", "content": "Thyroid function of the aged as viewed from the pituitary-thyroid system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217273"} {"pmid": "4217274", "title": "Serum thyrotropin response to thyrotropin releasing hormone and the concentration of thyroid hormone in patients with hyperfuncting thyroid nodule.", "content": "Serum thyrotropin response to thyrotropin releasing hormone and the concentration of thyroid hormone in patients with hyperfuncting thyroid nodule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217274"} {"pmid": "4217275", "title": "Effect of somatostatin (growth hormone inhibiting factor: GIF) on TRH-induced TSH release in rats.", "content": "Effect of somatostatin (growth hormone inhibiting factor: GIF) on TRH-induced TSH release in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217275"} {"pmid": "4217277", "title": "Glycosphingolipids and glycoproteins in the wild-type and in non-aggregating mutant of Dictyostelium discoideum.", "content": "Glycosphingolipids and glycoproteins in the wild-type and in non-aggregating mutant of Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217277"} {"pmid": "4217276", "title": "The preparation and characterization of two forms of bovine galactosyl transferase.", "content": "The preparation and characterization of two forms of bovine galactosyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217276"} {"pmid": "4217278", "title": "Reaction mechanism of D-galactose dehydrogenases from Pseudomonas saccharophila and Pseudomonas fluorescens. Formation and rearrangemnt of aldono-1,5-lactones.", "content": "Reaction mechanism of D-galactose dehydrogenases from Pseudomonas saccharophila and Pseudomonas fluorescens. Formation and rearrangemnt of aldono-1,5-lactones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217278"} {"pmid": "4217279", "title": "Effects of nitroglycerin on myocardial transmural differences in blood flow, oxygen and carbon dioxide tensions in normal and ischemic canine hearts.", "content": "Effects of nitroglycerin on myocardial transmural differences in blood flow, oxygen and carbon dioxide tensions in normal and ischemic canine hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217279"} {"pmid": "4217280", "title": "Effect of two different climates on severely burned rats infected with Pseudomonas aeruginosa.", "content": "Effect of two different climates on severely burned rats infected with Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217280"} {"pmid": "4217281", "title": "Hemoglobin synthesis inhibiting factor (HSIF). Chemical and biological characterizations.", "content": "Hemoglobin synthesis inhibiting factor (HSIF). Chemical and biological characterizations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217281"} {"pmid": "4217283", "title": "Pheromones in primate reproduction and social behavior.", "content": "Pheromones in primate reproduction and social behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217283"} {"pmid": "4217284", "title": "Proceedings: Solubilization of adenylate cyclase of rat corpora lutes.", "content": "Proceedings: Solubilization of adenylate cyclase of rat corpora lutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217284"} {"pmid": "4217285", "title": "Effect of furylfuramide, a potent mutagen, on reproduction and malformation.", "content": "Effect of furylfuramide, a potent mutagen, on reproduction and malformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217285"} {"pmid": "4217286", "title": "Physiology and pharmacology of PGs in parturition.", "content": "Physiology and pharmacology of PGs in parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217286"} {"pmid": "4217287", "title": "Transplacental haemorrhage in abortions.", "content": "Transplacental haemorrhage in abortions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217287"} {"pmid": "4217288", "title": "Protein malnutrition in the rat: its effects on maternal behavior and pup development.", "content": "Protein malnutrition in the rat: its effects on maternal behavior and pup development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217288"} {"pmid": "4217289", "title": "Experiences in the clinical management of amniotic alpha-fetoprotein estimations.", "content": "Experiences in the clinical management of amniotic alpha-fetoprotein estimations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217289"} {"pmid": "4217290", "title": "Characterization of Chinese hamsters by metabolic balance, glucose tolerance and insulin secretion.", "content": "Characterization of Chinese hamsters by metabolic balance, glucose tolerance and insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217290"} {"pmid": "4217291", "title": "The diabetic Chinese hamster: in vitro insulin and glucagon release; the \"\"chemical diabetic\";; and the effect of diet on ketonuria.", "content": "The diabetic Chinese hamster: in vitro insulin and glucagon release; the \"\"chemical diabetic\";; and the effect of diet on ketonuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217291"} {"pmid": "4217292", "title": "Morphological characterization of membrane systems in A- and B-cells of the Chinese hamster.", "content": "Morphological characterization of membrane systems in A- and B-cells of the Chinese hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217292"} {"pmid": "4217293", "title": "Segmental demyelination in the distal peripheral nerves of chronically diabetic Chinese hamsters.", "content": "Segmental demyelination in the distal peripheral nerves of chronically diabetic Chinese hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217293"} {"pmid": "4217294", "title": "The polyol pathway for glucose metabolism in tissues from normal, diabetic, and ketotic Chinese hamsters.", "content": "The polyol pathway for glucose metabolism in tissues from normal, diabetic, and ketotic Chinese hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217294"} {"pmid": "4217295", "title": "Hepatic and renal protein synthesis in normal, diabetic and ketotic Chinese hamsters.", "content": "Hepatic and renal protein synthesis in normal, diabetic and ketotic Chinese hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217295"} {"pmid": "4217297", "title": "Morphologic abnormalities observed in retina, pancreas and kidney of diabetic Chinese hamsters.", "content": "Morphologic abnormalities observed in retina, pancreas and kidney of diabetic Chinese hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217297"} {"pmid": "4217296", "title": "Effect of diet limitation on the development of diabetes in prediabetic Chinese hamsters.", "content": "Effect of diet limitation on the development of diabetes in prediabetic Chinese hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217296"} {"pmid": "4217299", "title": "Aortic glucose metabolism in the diabetic Chinese hamster.", "content": "Aortic glucose metabolism in the diabetic Chinese hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217299"} {"pmid": "4217298", "title": "Epidemiology of Chinese hamsters and preliminary evidence for genetic heterogeneity of diabetes.", "content": "Epidemiology of Chinese hamsters and preliminary evidence for genetic heterogeneity of diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217298"} {"pmid": "4217300", "title": "Characterization of diabetes mellitus in South African hamsters (Mystromys albicaudatus).", "content": "Characterization of diabetes mellitus in South African hamsters (Mystromys albicaudatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217300"} {"pmid": "4217303", "title": "Effects of population size and selection intensity on responses to disruptive selection in Drosophila melangaster.", "content": "Effects of population size and selection intensity on responses to disruptive selection in Drosophila melangaster. Disruptive selection for sternopleural bristle number with opportunity for random mating was done in the four treatment combinations of two population sizes (40 pairs and 8 pairs of selected parents) and two selection intensities (1 in 40 and 1 in 2). In each generation, matings among selected parents were observed in a mating chamber, and progeny collected separately from each female parent. In the high number, high selection intensity treatment, divergence between the high and low parts ceased about generation 11. The isolation index increased rapidly to generation 3, but then fluctuated to termination of the population at generation 17. The overall isolation index was significant, indicating a real tendency to assortative mating. The failure of the isolation index to increase after generation 3 was attributed to lower average mating fitness of high males (due to inbreeding) and reduced receptivity of low females (due to a homozygous lethal gene with a large effect on sternopleural bristle number in heterozygotes). In the two low number treatments, isolation indices fluctuated from generation to generation with no obvious trends, and none of the overall isolation indices were significantly different from zero. The high number, low selection intensity treatment showed very little divergence, and one of the replicates showed, in contrast with expectation and the high number, high selection intensity treatment, a significant tendency to disassortative mating. Intense disruptive selection may lead to assortative mating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217303"} {"pmid": "4217304", "title": "Steroid induction of the mRNA for hepatic tryptophan oxygenase.", "content": "Steroid induction of the mRNA for hepatic tryptophan oxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217304"} {"pmid": "4217305", "title": "Inhibitors of mammalian protein synthesis.", "content": "Inhibitors of mammalian protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217305"} {"pmid": "4217307", "title": "Pharmacology of Sintamil metabolites.", "content": "Pharmacology of Sintamil metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217307"} {"pmid": "4217308", "title": "Electron microscopic autoradiographic studies on polytene nuclei of Drosophila melanogaster: Part I. Replication and its relationship with nuclear membrane.", "content": "Electron microscopic autoradiographic studies on polytene nuclei of Drosophila melanogaster: Part I. Replication and its relationship with nuclear membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217308"} {"pmid": "4217309", "title": "Effect of mutation on the amylolytic and proteolytic activity of Bacillus subtilis isolated from domestic waste water.", "content": "Effect of mutation on the amylolytic and proteolytic activity of Bacillus subtilis isolated from domestic waste water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217309"} {"pmid": "4217310", "title": "Immunoglobulins in health and disease. II. IgE concentrations in the sera of patients with bronchial asthma.", "content": "Immunoglobulins in health and disease. II. IgE concentrations in the sera of patients with bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217310"} {"pmid": "4217311", "title": "Peroxidase-dependent oxidation of tyrosine to melanin in leucodermic vitiligenous skin.", "content": "Peroxidase-dependent oxidation of tyrosine to melanin in leucodermic vitiligenous skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217311"} {"pmid": "4217312", "title": "Some anthropologic investigations of interest to oral surgeons.", "content": "Some anthropologic investigations of interest to oral surgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217312"} {"pmid": "4217313", "title": "Surgical and orthodontic treatment of cleidocranial dysostosis.", "content": "Surgical and orthodontic treatment of cleidocranial dysostosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217313"} {"pmid": "4217314", "title": "Results of apicoectomy of maxillary canines, premolars and molars with special reference to oroantral communication as a prognostic factor.", "content": "Results of apicoectomy of maxillary canines, premolars and molars with special reference to oroantral communication as a prognostic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217314"} {"pmid": "4217316", "title": "Experimental reconstruction of the mandibular joint.", "content": "Experimental reconstruction of the mandibular joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217316"} {"pmid": "4217317", "title": "A radiographic and clinical follow-up study of 150 oroantral communications.", "content": "A radiographic and clinical follow-up study of 150 oroantral communications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217317"} {"pmid": "4217315", "title": "Use of propylic ester of p-hydroxy-benzoic acid after removal of impacted mandibular third molars.", "content": "Use of propylic ester of p-hydroxy-benzoic acid after removal of impacted mandibular third molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217315"} {"pmid": "4217319", "title": "Cilnical experiences in oral surgery using a new self-aspirating injection system.", "content": "Cilnical experiences in oral surgery using a new self-aspirating injection system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217319"} {"pmid": "4217318", "title": "Evaluation of carticaine - a new local analgesic.", "content": "Evaluation of carticaine - a new local analgesic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217318"} {"pmid": "4217320", "title": "The effect of mucin-containing artificial saliva on severe xerostomia.", "content": "The effect of mucin-containing artificial saliva on severe xerostomia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217320"} {"pmid": "4217321", "title": "A case of gigantiform cementoma.", "content": "A case of gigantiform cementoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217321"} {"pmid": "4217322", "title": "Report on an oral, pigmented, squamous cell carcinoma.", "content": "Report on an oral, pigmented, squamous cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217322"} {"pmid": "4217323", "title": "Some analyses of exsheathing fluid from infective Haemonchus contortus larvae from Ontario.", "content": "Some analyses of exsheathing fluid from infective Haemonchus contortus larvae from Ontario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217323"} {"pmid": "4217324", "title": "Evidence of a rat-snake life cycle for Sarcocystis.", "content": "Evidence of a rat-snake life cycle for Sarcocystis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217324"} {"pmid": "4217325", "title": "Stimultaneous determination of effective renal plasma flow and glomerular filtration rate by the \"single shot\" method.", "content": "Stimultaneous determination of effective renal plasma flow and glomerular filtration rate by the \"single shot\" method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217325"} {"pmid": "4217326", "title": "Enterovirus etiology of the 1970 Singapore epidemic of acute conjunctivitis.", "content": "Enterovirus etiology of the 1970 Singapore epidemic of acute conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217326"} {"pmid": "4217330", "title": "Genetic tests on Drosophila melanogaster with polychlorinated biphenyls (PCB).", "content": "Genetic tests on Drosophila melanogaster with polychlorinated biphenyls (PCB).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217330"} {"pmid": "4217331", "title": "Changes of zeste phenotype induced by autosomal mutations in Drosophila melanogaster.", "content": "Changes of zeste phenotype induced by autosomal mutations in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217331"} {"pmid": "4217332", "title": "Stabilising selection in constant and fluctuating environments.", "content": "Stabilising selection in constant and fluctuating environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217332"} {"pmid": "4217333", "title": "Phenotypic observations on modification of position-effect variegation in Drosophila melanogaster.", "content": "Phenotypic observations on modification of position-effect variegation in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217333"} {"pmid": "4217334", "title": "Studies on the nature and function of polygenic loci in Drosophila. I. Comparison of genomes from selection lines.", "content": "Studies on the nature and function of polygenic loci in Drosophila. I. Comparison of genomes from selection lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217334"} {"pmid": "4217335", "title": "Studies on the nature and function of polygenic loci in Drosophila. II. The subthreshold wing vein pattern revealed in selection experiments.", "content": "Studies on the nature and function of polygenic loci in Drosophila. II. The subthreshold wing vein pattern revealed in selection experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217335"} {"pmid": "4217337", "title": "Immunocytochemical demonstration of intestinal alkaline phosphatase.", "content": "Immunocytochemical demonstration of intestinal alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217337"} {"pmid": "4217336", "title": "The mechanism of metal binding to glutaraldehyde-fixed noradrenaline-storing adrenomedullary granules.", "content": "The mechanism of metal binding to glutaraldehyde-fixed noradrenaline-storing adrenomedullary granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217336"} {"pmid": "4217339", "title": "Proceedings: Numbers of neurons through full depth of neocortex.", "content": "Proceedings: Numbers of neurons through full depth of neocortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217339"} {"pmid": "4217340", "title": "Evidence for the association of RNA with the ciliary basal bodies of Tetrahymena.", "content": "Evidence for the association of RNA with the ciliary basal bodies of Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217340"} {"pmid": "4217341", "title": "The antagonistic effects of antimitotic agents on contraction and re-extension in the ciliate Spirostomum ambiguum.", "content": "The antagonistic effects of antimitotic agents on contraction and re-extension in the ciliate Spirostomum ambiguum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217341"} {"pmid": "4217342", "title": "Limpet haemocytes. III. Effects of cytochalasin B and colchicine on cell spreading and aggregation.", "content": "Limpet haemocytes. III. Effects of cytochalasin B and colchicine on cell spreading and aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217342"} {"pmid": "4217343", "title": "Penicillin control of swelling and pain after periodontal osseous surgery.", "content": "Penicillin control of swelling and pain after periodontal osseous surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217343"} {"pmid": "4217344", "title": "Schizophrenic response to affectivity in word definition.", "content": "Schizophrenic response to affectivity in word definition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217344"} {"pmid": "4217345", "title": "Tonsillolith and elongated styloid.", "content": "Tonsillolith and elongated styloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217345"} {"pmid": "4217347", "title": "A high frequency of fertilization in premature and mature coelomic toad eggs after enzymic removal removal removal of vitelline membrane.", "content": "A high frequency of fertilization in premature and mature coelomic toad eggs after enzymic removal removal removal of vitelline membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217347"} {"pmid": "4217348", "title": "Intracellular calcium binding and release in frog heart.", "content": "Intracellular calcium binding and release in frog heart. The capacities and affinities of intracellular calcium-binding sites have been studied in frog ventricles, in which the concentration of Ca(++) in the sarcoplasm can be controlled as a result of treatment with EDTA. The total calcium content of calcium-depleted and nondepleted muscles at rest and muscles generating considerable tension was 0.8, 1.4, and 5.4 micromol/g of muscle, respectively. Net movement of calcium into or out of the cells occurred without change in tension when the sarcoplasmic concentration of Ca(++) was either of two values, less than 10(-7) M or approximately 5 x 10(-7) M. These data can be explained by the presence of two groups of intracellular calcium sinks which compete with the contractile proteins, one with a capacity of about 0.6 micromol/g and an affinity constant greater than 10(7) M(-1) and a second with a capacity of 4.0 micromol/g and an affinity constant of about 2 x 10(6) M(-1). The higher affinity calcium is released by anoxia, oligomycin, or abrupt changes in sarcoplasmic Ca(++). Muscles soaked in Sr-Ringer's contain electron densities in the sarcoplasmic reticulum and to a lesser extent in the mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217348"} {"pmid": "4217349", "title": "Immunochemical identification of a new molecular form of acid phosphatase of host origin arising during infection of potato tubers by Phytophthora erythroseptica Pethybr.", "content": "Immunochemical identification of a new molecular form of acid phosphatase of host origin arising during infection of potato tubers by Phytophthora erythroseptica Pethybr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217349"} {"pmid": "4217350", "title": "The properties and host range of male-specific bacteriophages of Pseudomonas aeruginosa.", "content": "The properties and host range of male-specific bacteriophages of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217350"} {"pmid": "4217351", "title": "Nitrification by aflatoxigenic strains of Aspergillus flavus and Aspergillus parasiticus.", "content": "Nitrification by aflatoxigenic strains of Aspergillus flavus and Aspergillus parasiticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217351"} {"pmid": "4217352", "title": "Establishment of a limited rumen flora in gnotobiotic lambs fed on a roughage diet.", "content": "Establishment of a limited rumen flora in gnotobiotic lambs fed on a roughage diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217352"} {"pmid": "4217354", "title": "The utilization of Bacillus megaterium and the release of a lytic enzyme by three Epidinium spp. isolated from the rumen.", "content": "The utilization of Bacillus megaterium and the release of a lytic enzyme by three Epidinium spp. isolated from the rumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217354"} {"pmid": "4217353", "title": "The metabolism of starch, glucose, amino acids, purines, pyrimidines and bacteria by three Epidinium spp. isolated from the rumen.", "content": "The metabolism of starch, glucose, amino acids, purines, pyrimidines and bacteria by three Epidinium spp. isolated from the rumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217353"} {"pmid": "4217355", "title": "The metabolism of Epidinium ecaudatum caudatum and Entodinium caudatum as shown by autoradiography in the electron microscope.", "content": "The metabolism of Epidinium ecaudatum caudatum and Entodinium caudatum as shown by autoradiography in the electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217355"} {"pmid": "4217356", "title": "A co-operative numerical analysis of cultures considered to belong to the 'rhodochrous' taxon.", "content": "A co-operative numerical analysis of cultures considered to belong to the 'rhodochrous' taxon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217356"} {"pmid": "4217357", "title": "Mucopeptide synthesis by rod mutants of Bacillus subtilis.", "content": "Mucopeptide synthesis by rod mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217357"} {"pmid": "4217358", "title": "Temperature sensitivity of sporulation in Bacillus cereus.", "content": "Temperature sensitivity of sporulation in Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217358"} {"pmid": "4217359", "title": "Prostaglandins and the anti-inflammatory activity of a human plasma fraction in carrageenan-induced paw oedema in the rat.", "content": "Prostaglandins and the anti-inflammatory activity of a human plasma fraction in carrageenan-induced paw oedema in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217359"} {"pmid": "4217360", "title": "Ionic relations and electrical properties of isolated oocytes of Bufo bufo with special reference to removal of extracellular chloride.", "content": "Ionic relations and electrical properties of isolated oocytes of Bufo bufo with special reference to removal of extracellular chloride. 1. The efflux rate coefficients of sodium, potassium and chloride from immature oocytes of the toad Bufo bufo have been measured and found to be respectively, 0.0069, 0.0023 and 0.0034 min(-1).2. Replacement of external chloride by sulphate resulted in a fall in chloride efflux of about 50%. This has been interpreted in terms of exchange diffusion.3. The membrane conductance has been measured and found to be 0.14 x 10(-3) mhos cm(-2) in good agreement with the value calculated from the flux data, 0.12 x 10(-3) mhos cm(-2), after taking account of the chloride exchange diffusion fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217360"} {"pmid": "4217361", "title": "The effect of holding potential on the asymmetry currents in squid gaint axons.", "content": "The effect of holding potential on the asymmetry currents in squid gaint axons. 1. Asymmetry currents were recorded from intracellularly perfused squid axons subjected to an equal number of exactly equal positive and negative voltage clamp pulses. The asymmetry currents consisted of an on-response at the beginning of the pulses and an off-response at the end of the pulses.2. The asymmetry currents were markedly reduced by 30 mM glutaraldehyde applied internally.3. Clamp pulses of varying height, superimposed on a holding potential of - 80 to - 100 mV, were used to study the voltage and time dependence of the asymmetry current. The magnitude of the on- and off-response increased with increasing pulse height along a sigmoid curve. The time constants of the on- and off-response depended on the potential during the depolarizing pulses; the time constant of the on-response had a maximum at an internal potential of - 12 mV, the time constant of the off-response was largest at positive internal potentials.4. Holding the membrane at a potential of - 80 to - 100 mV for several minutes led to a slow increase of the size of the asymmetry current.5. Changing the holding potential from - 80 or - 100 mV to a less negative potential caused a decrease of the asymmetry current. At holding potentials less negative than - 65 or - 60 mV the asymmetry current reversed its sign: the transient current at the beginning of the pulses turned into an inward current and the transient current at the end of the pulses became outward. No inactivation of the asymmetry current was seen in the range of holding potentials studied (V < - 3 mV).6. The results are generally consistent with the idea that the asymmetry currents are in some way related to the opening and closing of the Na gates; they suggest, however, that the asymmetrical charge movement does not simply reflect the voltage and time dependence of the m system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217361"} {"pmid": "4217366", "title": "Haemogregarina pseudemydis n. sp. (Apicomplexa: Haemogregarinidae) and Pirhemocyton chelonarum n. sp. in turtles from Louisiana.", "content": "Haemogregarina pseudemydis n. sp. (Apicomplexa: Haemogregarinidae) and Pirhemocyton chelonarum n. sp. in turtles from Louisiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217366"} {"pmid": "4217367", "title": "Cryptosporidium anserinum sp. n. (Sporozoa) in a domestic goose Anser anser L., from Iowa.", "content": "Cryptosporidium anserinum sp. n. (Sporozoa) in a domestic goose Anser anser L., from Iowa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217367"} {"pmid": "4217368", "title": "Fine structure of the cyst and some sporulation stages of Ichthyosporidium (Microsporida).", "content": "Fine structure of the cyst and some sporulation stages of Ichthyosporidium (Microsporida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217368"} {"pmid": "4217369", "title": "Terebrospira chattoni sp. n., a parasite of the endocuticle of the shrimp Palaemonetes pugio Holthuis.", "content": "Terebrospira chattoni sp. n., a parasite of the endocuticle of the shrimp Palaemonetes pugio Holthuis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217369"} {"pmid": "4217370", "title": "Diplodinium flabellum: occurrence and numbers in the rumen of sheep with a description of two new subspecies.", "content": "Diplodinium flabellum: occurrence and numbers in the rumen of sheep with a description of two new subspecies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217370"} {"pmid": "4217371", "title": "Ultrastructure of symbiotic bacteria in normal and antibiotic-treated Blastocrithidia culicis and Crithidia oncopelti.", "content": "Ultrastructure of symbiotic bacteria in normal and antibiotic-treated Blastocrithidia culicis and Crithidia oncopelti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217371"} {"pmid": "4217372", "title": "Besnoitia jellisoni in macrophages and cysts from experimentally infected laboratory mice.", "content": "Besnoitia jellisoni in macrophages and cysts from experimentally infected laboratory mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217372"} {"pmid": "4217373", "title": "Ultrastructural localization of acid phosphatase in starved Tokophrya infusionum.", "content": "Ultrastructural localization of acid phosphatase in starved Tokophrya infusionum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217373"} {"pmid": "4217374", "title": "Studies of membrane formation in Tetrahymena pyriformis. VIII. On the origin of membranes surrounding food vacuoles.", "content": "Studies of membrane formation in Tetrahymena pyriformis. VIII. On the origin of membranes surrounding food vacuoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217374"} {"pmid": "4217376", "title": "Isolation and characterization of kinetoplast DNA networks and minicircles from Crithidia fasciculata.", "content": "Isolation and characterization of kinetoplast DNA networks and minicircles from Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217376"} {"pmid": "4217375", "title": "Beta-oxidation in glyoxysomes from Euglena.", "content": "Beta-oxidation in glyoxysomes from Euglena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217375"} {"pmid": "4217377", "title": "Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae.", "content": "Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217377"} {"pmid": "4217378", "title": "Immunogenicity of the delta-haemolysin of Staphylococcus aureus.", "content": "Immunogenicity of the delta-haemolysin of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217378"} {"pmid": "4217379", "title": "Candida serology in open-heart surgery.", "content": "Candida serology in open-heart surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217379"} {"pmid": "4217380", "title": "Antibiotic-resistant gram-negative bacilli in the faeces of neonates.", "content": "Antibiotic-resistant gram-negative bacilli in the faeces of neonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217380"} {"pmid": "4217381", "title": "Rapid group and species identification of enterococci by means of tests with pooled phages.", "content": "Rapid group and species identification of enterococci by means of tests with pooled phages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217381"} {"pmid": "4217382", "title": "Immunoglobulin levels as related to age in nonhuman primates in captivity. I. Chimpanzees.", "content": "Immunoglobulin levels as related to age in nonhuman primates in captivity. I. Chimpanzees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217382"} {"pmid": "4217383", "title": "Immunoglobulin levels as related to age in nonhuman primates in captivity. II. Rhesus monkeys.", "content": "Immunoglobulin levels as related to age in nonhuman primates in captivity. II. Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217383"} {"pmid": "4217384", "title": "Restraining chair and face mask for inhalation toxicology studies in primates.", "content": "Restraining chair and face mask for inhalation toxicology studies in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217384"} {"pmid": "4217385", "title": "Cutis verticis gyrata in a Chinese mental defective.", "content": "Cutis verticis gyrata in a Chinese mental defective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217385"} {"pmid": "4217386", "title": "Letter to editor: Subunit arrangements in bacterial flagella.", "content": "Letter to editor: Subunit arrangements in bacterial flagella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217386"} {"pmid": "4217387", "title": "A study of the histidine residues of human carbonic anhydrase B using 270 MHz proton magnetic resonance.", "content": "A study of the histidine residues of human carbonic anhydrase B using 270 MHz proton magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217387"} {"pmid": "4217388", "title": "The effects of fusidic acid on growth, ribosome synthesis and RNA metabolism in Escherichia coli.", "content": "The effects of fusidic acid on growth, ribosome synthesis and RNA metabolism in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217388"} {"pmid": "4217389", "title": "Infant malnutrition in Africa: the rôle of artificial milk feeds.", "content": "Infant malnutrition in Africa: the rôle of artificial milk feeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217389"} {"pmid": "4217390", "title": "Measuring the recovery rates of malnourished children from their weight-gains. Part I: review of existing methods.", "content": "Measuring the recovery rates of malnourished children from their weight-gains. Part I: review of existing methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217390"} {"pmid": "4217391", "title": "Measuring the recovery rates of malnourished children from their weight-gains. Part II: discussion of a new technique.", "content": "Measuring the recovery rates of malnourished children from their weight-gains. Part II: discussion of a new technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217391"} {"pmid": "4217404", "title": "Studies on the modification of the live AIK measles vaccine. I. Adaptation of the further attenuated AIK measles virus (the strain AIK-L33) to chick embryo cells.", "content": "Studies on the modification of the live AIK measles vaccine. I. Adaptation of the further attenuated AIK measles virus (the strain AIK-L33) to chick embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217404"} {"pmid": "4217405", "title": "Protein composition of cell and forespore membranes of Bacillus subtilis.", "content": "Protein composition of cell and forespore membranes of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217405"} {"pmid": "4217407", "title": "Unusual fracture and orthopedic problems.", "content": "Unusual fracture and orthopedic problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217407"} {"pmid": "4217412", "title": "Antimicrobial activity of cultured plant cells and tissues.", "content": "Antimicrobial activity of cultured plant cells and tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217412"} {"pmid": "4217413", "title": "Hydrophobic chromatography.", "content": "Hydrophobic chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217413"} {"pmid": "4217414", "title": "Affinity density perturbation.", "content": "Affinity density perturbation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217414"} {"pmid": "4217415", "title": "Pteroyllysine-agarose in the purification of dihydrofolate reductase.", "content": "Pteroyllysine-agarose in the purification of dihydrofolate reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217415"} {"pmid": "4217417", "title": "Isolation of beta-galactosidase by chromatography.", "content": "Isolation of beta-galactosidase by chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217417"} {"pmid": "4217416", "title": "Group-specific separation of glycoproteins.", "content": "Group-specific separation of glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217416"} {"pmid": "4217418", "title": "Alpha-lactalbumin-agarose. A specific adsorbent for a galactosyltransferase.", "content": "Alpha-lactalbumin-agarose. A specific adsorbent for a galactosyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217418"} {"pmid": "4217419", "title": "Use of thyroxine in affinity chromatography.", "content": "Use of thyroxine in affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217419"} {"pmid": "4217420", "title": "Covalent affinity chromatography of penicillin-binding components from bacterial membranes.", "content": "Covalent affinity chromatography of penicillin-binding components from bacterial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217420"} {"pmid": "4217422", "title": "Purification of thymidylate synthetase with 2'-deoxyuridylate-agarose.", "content": "Purification of thymidylate synthetase with 2'-deoxyuridylate-agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217422"} {"pmid": "4217421", "title": "Affinity chromatography of thermolysin and other neutral metalloendopeptidases.", "content": "Affinity chromatography of thermolysin and other neutral metalloendopeptidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217421"} {"pmid": "4217425", "title": "Editorial: The hunger striker.", "content": "Editorial: The hunger striker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217425"} {"pmid": "4217431", "title": "Effects of dexamthasone and secobarbital on the pituitary response to thryotropin releasing hormone (TRH) in man: synergistic inhibition of thyrotropin (TSH) release.", "content": "Effects of dexamthasone and secobarbital on the pituitary response to thryotropin releasing hormone (TRH) in man: synergistic inhibition of thyrotropin (TSH) release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217431"} {"pmid": "4217435", "title": "Gentamicin by intravenous bolus injection.", "content": "Gentamicin by intravenous bolus injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217435"} {"pmid": "4217427", "title": "Physical aspects of supervoltage x-ray therapy.", "content": "Physical aspects of supervoltage x-ray therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217427"} {"pmid": "4217436", "title": "Chemotherapy of malignant mesothelioma.", "content": "Chemotherapy of malignant mesothelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217436"} {"pmid": "4217437", "title": "The diagnosis of subclinical mastitis in lactating cows: a comparison of cytological methods and a monovalent radial immunodiffusion test.", "content": "The diagnosis of subclinical mastitis in lactating cows: a comparison of cytological methods and a monovalent radial immunodiffusion test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217437"} {"pmid": "4217438", "title": "Chemoprophylaxis of bladder cancer recurrence: immunological aspects.", "content": "Chemoprophylaxis of bladder cancer recurrence: immunological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217438"} {"pmid": "4217442", "title": "Residues of organochlorine insecticides and PCBs in samples of Norwegian butter 1972.", "content": "Residues of organochlorine insecticides and PCBs in samples of Norwegian butter 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217442"} {"pmid": "4217445", "title": "Membrane attachment of the chromosome in Bacillus subtilis mutants temperature-sensitive in DNA replication.", "content": "Membrane attachment of the chromosome in Bacillus subtilis mutants temperature-sensitive in DNA replication. We have examined three mutants of Bacillussubtilis temperature sensitive in DNA initiation and one temperature sensitive in DNA elongation, in order to investigate whether these lesions can cause or can result in a detachment of the membrane-bound chromosomal region. Our results argue against any effect of the mutations examined on the association between the chromosome and the membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217445"} {"pmid": "4217448", "title": "Radiotherapy.", "content": "Radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217448"} {"pmid": "4217449", "title": "Acute barbiturate poisoning in young epileptics.", "content": "Acute barbiturate poisoning in young epileptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217449"} {"pmid": "4217454", "title": "Accuracy of measurements of potassium content of monkeys by in vivo body counting as compared to chemical analysis.", "content": "Accuracy of measurements of potassium content of monkeys by in vivo body counting as compared to chemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217454"} {"pmid": "4217455", "title": "The use of nuclear track detectors in the design of neutron collimators and scatterers.", "content": "The use of nuclear track detectors in the design of neutron collimators and scatterers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217455"} {"pmid": "4217457", "title": "A kinetic study on inorganic polyphosphate glucokinase from Mycobacterium tuberculosis H37RA.", "content": "A kinetic study on inorganic polyphosphate glucokinase from Mycobacterium tuberculosis H37RA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217457"} {"pmid": "4217458", "title": "The comparison of thyrotropin releasing hormone, luteinising hormone-releasing hormone and placebo in depressive patients using a double-blind cross-over technique.", "content": "The comparison of thyrotropin releasing hormone, luteinising hormone-releasing hormone and placebo in depressive patients using a double-blind cross-over technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217458"} {"pmid": "4217459", "title": "Sex and long-term care.", "content": "Sex and long-term care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217459"} {"pmid": "4217461", "title": "Thio-tepa and endoxan in combined treatment of breast cancer (cooperative trial).", "content": "Thio-tepa and endoxan in combined treatment of breast cancer (cooperative trial).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217461"} {"pmid": "4217467", "title": "Results of faecal examinations with special regard to vibrios in tourists returning from the same area as a verified case of cholera.", "content": "Results of faecal examinations with special regard to vibrios in tourists returning from the same area as a verified case of cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217467"} {"pmid": "4217466", "title": "Tobramycin treatment of pseudomonas aeruginosa infections in cystic fibrosis.", "content": "Tobramycin treatment of pseudomonas aeruginosa infections in cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217466"} {"pmid": "4217468", "title": "Meningococcemia due to neisseria meningitidis serogroup D.", "content": "Meningococcemia due to neisseria meningitidis serogroup D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217468"} {"pmid": "4217470", "title": "In vitro assay of malignant transformation by the oncogenic adenovirus SA7.", "content": "In vitro assay of malignant transformation by the oncogenic adenovirus SA7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217470"} {"pmid": "4217471", "title": "The presence of Capillaria hepatica (Bancroft, 1893) Travassos, 1915 in a vervet monkey Cercopithecus aethiops.", "content": "The presence of Capillaria hepatica (Bancroft, 1893) Travassos, 1915 in a vervet monkey Cercopithecus aethiops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217471"} {"pmid": "4217472", "title": "Pattern of biochemical and immune recovery in protein calorie malnutrition.", "content": "Pattern of biochemical and immune recovery in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217472"} {"pmid": "4217473", "title": "The role of releasing hormones in the diagnosis of hypopituitarism. An analysis of 9 patients.", "content": "The role of releasing hormones in the diagnosis of hypopituitarism. An analysis of 9 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217473"} {"pmid": "4217474", "title": "Oesophageal motor dysfunction in patients with diverticula of the mid-thoracic oesophagus.", "content": "Oesophageal motor dysfunction in patients with diverticula of the mid-thoracic oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217474"} {"pmid": "4217475", "title": "Fibrinogen-fibrin-related antigen pattern in human blood. Differences between plasma and serum from pateints with disseminated intravascular coagulation.", "content": "Fibrinogen-fibrin-related antigen pattern in human blood. Differences between plasma and serum from pateints with disseminated intravascular coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217475"} {"pmid": "4217476", "title": "Rapid detection and quantitation of precipitating streptokinase-antibodies.", "content": "Rapid detection and quantitation of precipitating streptokinase-antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217476"} {"pmid": "4217477", "title": "Indirect measruement of streptokinase concentration in the plasma of patients undergoing fibrinolytic treatment.", "content": "Indirect measruement of streptokinase concentration in the plasma of patients undergoing fibrinolytic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217477"} {"pmid": "4217478", "title": "Long-term effects of ionizing radiation on drosophila midgut mitochondria.", "content": "Long-term effects of ionizing radiation on drosophila midgut mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217478"} {"pmid": "4217479", "title": "Dose distribution measurements in electron lens therapy with a 45 MeV betatron.", "content": "Dose distribution measurements in electron lens therapy with a 45 MeV betatron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217479"} {"pmid": "4217483", "title": "The treatment of peritonitis in patients with chronic indwelling catheters.", "content": "The treatment of peritonitis in patients with chronic indwelling catheters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217483"} {"pmid": "4217484", "title": "A compact portable prosthesis for total parenteral nutrition (t.p.n.): ambulatory parenteral feeding in the hospital and home.", "content": "A compact portable prosthesis for total parenteral nutrition (t.p.n.): ambulatory parenteral feeding in the hospital and home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217484"} {"pmid": "4217485", "title": "Serum middle molecule levels in uremia during long term intermittent hemoperfusions with the acac (coated charcoal) microcapsule artificial kidney.", "content": "Serum middle molecule levels in uremia during long term intermittent hemoperfusions with the acac (coated charcoal) microcapsule artificial kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217485"} {"pmid": "4217497", "title": "Lankesterella from an East African crowned crane Balearica pavonina gibbericeps.", "content": "Lankesterella from an East African crowned crane Balearica pavonina gibbericeps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217497"} {"pmid": "4217498", "title": "Swine vesicular disease: a serological vurvey of pigs presented for slaughter.", "content": "Swine vesicular disease: a serological vurvey of pigs presented for slaughter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217498"} {"pmid": "4217500", "title": "Vaccinal immunity to Marek's disease in bursectomised chickens.", "content": "Vaccinal immunity to Marek's disease in bursectomised chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217500"} {"pmid": "4217499", "title": "Placental structure and transmission of maternal immunity.", "content": "Placental structure and transmission of maternal immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217499"} {"pmid": "4217523", "title": "Extrarenal lipid inhibitors of human erythropoietin.", "content": "Extrarenal lipid inhibitors of human erythropoietin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217523"} {"pmid": "4217524", "title": "DNA replication of human acute leukemia cells cultured in vitro.", "content": "DNA replication of human acute leukemia cells cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217524"} {"pmid": "4217525", "title": "Haemolysis and erythrocyte lipids in thalassaemia major.", "content": "Haemolysis and erythrocyte lipids in thalassaemia major.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217525"} {"pmid": "4217527", "title": "Haemoglobin E variants and pregnancy in Malaysian aborigines.", "content": "Haemoglobin E variants and pregnancy in Malaysian aborigines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217527"} {"pmid": "4217528", "title": "Factor X survival and therapeutic factor X levels in the abnormal factor X (factor X FRIULI) COAGULATION DISORDER.", "content": "Factor X survival and therapeutic factor X levels in the abnormal factor X (factor X FRIULI) COAGULATION DISORDER.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217528"} {"pmid": "4217530", "title": "Proliferation of erythroblasts in refractory anaemia. A combined autoradiographic and cytophotometric study.", "content": "Proliferation of erythroblasts in refractory anaemia. A combined autoradiographic and cytophotometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217530"} {"pmid": "4217531", "title": "In vitro response of bone marrow cells to erythropoietin in aplastic anemia.", "content": "In vitro response of bone marrow cells to erythropoietin in aplastic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217531"} {"pmid": "4217532", "title": "67Ga scanning in the staging of Hodgkin's disease.", "content": "67Ga scanning in the staging of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217532"} {"pmid": "4217534", "title": "Structure and function of haemoglobin Tacoma (beta 30 Arg yields Ser) found in a second family.", "content": "Structure and function of haemoglobin Tacoma (beta 30 Arg yields Ser) found in a second family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217534"} {"pmid": "4217535", "title": "Congenital dyserythropoietic anaemia type II. Clinical and ultrastructural study.", "content": "Congenital dyserythropoietic anaemia type II. Clinical and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217535"} {"pmid": "4217536", "title": "Hereditary disorders of bilirubin metabolism.", "content": "Hereditary disorders of bilirubin metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217536"} {"pmid": "4217537", "title": "The activity of intestinal disaccharidases and dipeptidases in rats with chronic renal insufficiency.", "content": "The activity of intestinal disaccharidases and dipeptidases in rats with chronic renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217537"} {"pmid": "4217540", "title": "Histochemical studies on the morphology of the Golgi apparatus and on the distribution of hexokinase, amylophosphorylase, cholinesterases, and monoamine oxidase in the area postrema of the Asiatic chipmunk, Tamias sibiricus asiaticus (T. orientalis).", "content": "Histochemical studies on the morphology of the Golgi apparatus and on the distribution of hexokinase, amylophosphorylase, cholinesterases, and monoamine oxidase in the area postrema of the Asiatic chipmunk, Tamias sibiricus asiaticus (T. orientalis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217540"} {"pmid": "4217542", "title": "The surface of dissected neurons, neurons in smears, cultivated cells and sections as studied by means of scanning electron microscopy.", "content": "The surface of dissected neurons, neurons in smears, cultivated cells and sections as studied by means of scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217542"} {"pmid": "4217546", "title": "Quantitative aspects of the colloidal iron reaction.", "content": "Quantitative aspects of the colloidal iron reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217546"} {"pmid": "4217545", "title": "Histochemical analysis of thiamine pyrophosphatase activity in the developing molar tooth of the neonatal swiss albino mouse.", "content": "Histochemical analysis of thiamine pyrophosphatase activity in the developing molar tooth of the neonatal swiss albino mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217545"} {"pmid": "4217548", "title": "Ancient ophthalmological agents.", "content": "Ancient ophthalmological agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217548"} {"pmid": "4217549", "title": "Proceedings: Visual information processing, colour vision and spatial localization.", "content": "Proceedings: Visual information processing, colour vision and spatial localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217549"} {"pmid": "4217547", "title": "Modified method of demonstration for zinc in tissues and its mode of existence.", "content": "Modified method of demonstration for zinc in tissues and its mode of existence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217547"} {"pmid": "4217550", "title": "The treatment of hypercatabolic acute renal failure by adequate nutrition and haemodialysis.", "content": "The treatment of hypercatabolic acute renal failure by adequate nutrition and haemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217550"} {"pmid": "4217551", "title": "A brain-specific water-soluble antigen in homogenates of cat cerebral cortex.", "content": "A brain-specific water-soluble antigen in homogenates of cat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217551"} {"pmid": "4217554", "title": "The value of histology, culture and guinea pig inoculation examination in osteo-articular tuberculosis.", "content": "The value of histology, culture and guinea pig inoculation examination in osteo-articular tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217554"} {"pmid": "4217553", "title": "Neuropathological and biochemical studies in Fabry's disease.", "content": "Neuropathological and biochemical studies in Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217553"} {"pmid": "4217555", "title": "Bowel diseases involving local immunoglobulin systems.", "content": "Bowel diseases involving local immunoglobulin systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217555"} {"pmid": "4217556", "title": "Influence of synthetic polynucleotides and interferon on in vitro growth of cells derived from a mouse sarcoma.", "content": "Influence of synthetic polynucleotides and interferon on in vitro growth of cells derived from a mouse sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217556"} {"pmid": "4217557", "title": "Effects of radiation therapy on blood-borne leucocytes in patients with mammary carcinoma.", "content": "Effects of radiation therapy on blood-borne leucocytes in patients with mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217557"} {"pmid": "4217559", "title": "Atherosclerosis in pigeons and squirrel monkeys.", "content": "Atherosclerosis in pigeons and squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217559"} {"pmid": "4217558", "title": "Absorption of polymyxin E (colistin) by Corynebacterium diphtheriae.", "content": "Absorption of polymyxin E (colistin) by Corynebacterium diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217558"} {"pmid": "4217560", "title": "Social factors and atherosclerosis.", "content": "Social factors and atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217560"} {"pmid": "4217561", "title": "Immunologial aspects of atherosclerosis.", "content": "Immunologial aspects of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217561"} {"pmid": "4217562", "title": "On species of leucocytozoon.", "content": "On species of leucocytozoon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217562"} {"pmid": "4217563", "title": "Recent advances in antimalarial chemotherapy and drug resistance.", "content": "Recent advances in antimalarial chemotherapy and drug resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217563"} {"pmid": "4217566", "title": "Trypanosoma cruzi and virological studies in idiopathic cardiomyopathy in Cali, Colombia.", "content": "Trypanosoma cruzi and virological studies in idiopathic cardiomyopathy in Cali, Colombia. During a 10-year period a series of 114 patients was studied to determine if Trypanosoma cruzi and arboviruses could be the etiologic agents of idiopathic cardiomyopathy (ICM) in Cali, Colombia. In this area, ICM (together with rheumatic and artherosclerotic cardiopathy) represents the second most frequent cause (determined by necropsy) among adult patients with cardiopathies, hypertension being the first. No association was observed between ICM and any of the arboviruses assessed by hemagglutination tests. Only 10 of 114 cases (8.7%) showed positive seroparasitological tests for T. cruzi. Autopsy was performed in 4 of these 10 cases; 1 had Chagas myocarditis and the other 3 were patients with non-inflammatory ICM. In all 9 T. cruzi-negative cases the autopsies showed non-inflammatory ICM lesions. In contrast to typical Chagas cases, the most frequent EKG change in ICM is left bundle branch block rather than right. Since the EKG varies within either group, this distinction may not be valid in individual cases. Because of the similarities in clinical characteristics and variations in EKG between Chagas myocarditis and ICM, it is suggested that autopsies should be done in populations in endemic areas of T. cruzi to assess the frequency of ICM and its importance in the differential diagnosis of Chagas myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217566"} {"pmid": "4217565", "title": "Evidence for defective immunoglobulin metabolism in severe renal insufficiency.", "content": "Evidence for defective immunoglobulin metabolism in severe renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217565"} {"pmid": "4217567", "title": "The prevalence of trypanosomes and microfilariae in Panamanian monkeys.", "content": "The prevalence of trypanosomes and microfilariae in Panamanian monkeys. A total of 3,523 wild caught monkeys from Panama was examined for blood parasites from August 1968 through June 1972. Trypanosomes or microfilariae were observed in the blood of 31.1% of the monkeys. Mixed infections, with microfilariae and trypanosomes, were detected in 6.6% of the animals. Trypanosoma cruzi was found in marmosets. Saguinus geoffroyi (12.2%), in white-faced capuchins, Cebus capucinus (5.0%), in squirrel monkeys, Saimiri sciureus (1.7%) and in black spider monkeys, Ateles fusciceps (1.2%). Trypanosoma rangeli was found in S. geoffroyi (55.8%) and C. capucinus (12.5%). Other trypanosomes found in Panamanian monkeys included T. minasense, and T. mycetae. Saguinus geoffroyi showed the highest infection rate (88.9%) with trypanosomes and/or microfilariae; trypanosomes were seen in 68.1%, and microfilariae in 73.0%, of the animals examined. The marmosets, white-faced capuchins, and squirrel monkeys should be considered as significant hosts of T. cruzi in sylvatic habitats and may serve as reservoir hosts of Chagas' disease in Panama. The microfilariae seen in monkeys from Panama were tentatively identified as larval forms of Dipetalonema gracile in Aotus trivirgatus; D. obtusa in C. capucinus and S. geoffroyi; and D. marmosetae in Alowatta villosa, C. capucinus, A. trivirgatus, S. sciureus, A. fusciceps, and S. geoffroyi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217567"} {"pmid": "4217568", "title": "Single and repeated infections of grivet monkeys with Schistosoma mansoni: parasitological and pathological observations over a 31-month period.", "content": "Single and repeated infections of grivet monkeys with Schistosoma mansoni: parasitological and pathological observations over a 31-month period. Groups of 6 to 8 grivet monkeys (Ceropithecus aethiops aethiops), each of which had been exposed to 600 cercariae of Schistosoma mansoni, were killed 3, 6, and 31 months after exposure. Other groups of monkeys were repeatedly challenged with cercariae beginning 4 or 23 months after the initial infection, and were killed 31 months after the first exposure. Peripheral blood leukocytes, eosinophiles, and schistosome eggs passed in the feces were determined during the course of the infection. At autopsy, gross and histopathologic observations were made, worms were recovered by perfusion, and the number of eggs in the tissues was determined by digestion. Monkeys became acutely ill about 8 weeks after the initial exposure, and death was attributed to acute'toxemic' schistosomiasis in 4 of 46 infected animals. The symptoms and signs of the acute phase did not recur with reinfection. Most subsequent natural deaths were caused by Klebsiella infection which occurred in both infected and control monkeys and did not appear to be related to the schistosome infection. Relatively stable infections were found after a single exposure to cercariae, with only a slight decrease in worm numbers and moderate decrease in egg passage after 31 months. With repeated reinfection, only 19% of challenge cercariae developed into adult worms. Oviposition by these worms was delayed and the rate of oviposition was substantially less than in monkeys infected only once. Eggs deposited in the tissues were rapidly destroyed. The calculated rate of oviposition varied from 658 eggs/day per female 3 months after a single infection to 299 eggs/ day per female 31 months after repeated infections. Although very heavy infections were present in repeatedly infected monkeys, only slight hepatic fibrosis was seen and no portal hypertension or portal-systemic collateral circulation developed. Severe intestinal disease was present in only two monkeys. The remaining animals had little diarrhea after the acute phase, and there was only slight loss of plasma protein into the feces 31 months after exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217568"} {"pmid": "4217570", "title": "Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. I. Clinical course.", "content": "Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. I. Clinical course. Fifteen grivet monkeys, Cercopithecus aethiops, were infected with an Ethiopian strain of Borrelia recurrentis, the causative agent of louse-borne relapsing fever. An initial spirochetemia occurred in all. Inactivity, fever, and leukocytosis accompanied the infections. Eight of the monkeys experienced 1 relapse and 1 monkey had 2 relapses. The relapses tended to be less severe than the initial infections. The only deaths, however, occurred in 2 of the 3 monkeys with severe relapses. The clinical course of the experimental infection in grivet monkeys closely resembles that of natural infections in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217570"} {"pmid": "4217569", "title": "Administration and evaluation of rural health services. I. A tetanus control program in Haiti.", "content": "Administration and evaluation of rural health services. I. A tetanus control program in Haiti. Tetanus has been a public health problem of major importance in rural Haiti. Energetic preventive measures by a rural Haitian hospital were successful in controlling the problem only after immunization services were made easily available to the entire population served by the hospital. This was accomplished by a program which carried the services to the market places and villages of the region. The program developed several new categories of auxiliary personnel who were recruited locally and trained on the job. These personnel were utilized in a program which incorporated preparatory publicity, timing, handling of large crowds in open surroundings, education, record keeping, follow-up and evulation as well as the technical matters concerning the giving of injections. The program sharply reduced the number of admissions to the hospital for the treatment of tetanus. Evaluated on the basis of hospitalizations avverted the program cost only 1/9 the value of the 50,000 hospital days of care for the tetanus cases it prevented. A rural hospital in Haiti -- the Albert Schweitzer Hospital of Deschapelles -- initiated an energetic preventive program to deal with the public health problem of tetanus. The program was successful in controlling the problem only after immunization services were made easily available to the entire population served by the hospital. The program offered services in the market places and villages of the region. Several new categories of auxiliary personnel were recruited locally and trained on the job. The program incorporated preparatory publicity, timing, handling of large crowds in open surroundings, education, record keeping, follow-up and evaluation and the technical administration of the injections. The program was responsible for a marked reduction in the number of admissions to the hospital for the treatment of tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217569"} {"pmid": "4217571", "title": "Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. II. Pathology.", "content": "Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. II. Pathology. Nineteen grivet monkeys, Cercopithecus aethiops, were infected with the spirochete of louse-borne relapsing fever, Borrelia recurrentis, and killed at various intervals following inoculation: 4 during the initial spirochetemia; 4 during remission; 3 during relapse; 2 that were dying following severe relapses; and 6 during convalescence. The histologic changes of histiocytic myocarditis, multiple microabscesses replacing the nodular white pulp of the spleen, and hepatitis with foci of midzonal necrosis were similar to those seen in humans. These changes are rarely seen in other infectious diseases and suggest a specific toxic effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217571"} {"pmid": "4217572", "title": "Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. III. Crisis following therapy.", "content": "Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. III. Crisis following therapy. Eight grivet monkeys infected with Borrelia recurrentis received tetracycline (12.5mg/kg body weight) on the 3rd or 4th day of spirochetemia. Leukopenia, fever, hyperpnea, and tachycardia developed within 2 hours as spirochete counts fell to undetectable levels. These events closely simulated the crisis in human louse-borne relapsing fever in both timing and extent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217572"} {"pmid": "4217573", "title": "Abnormal patterns of ossification in foot bones of rat fetuses induced by cyclophosphamide.", "content": "Abnormal patterns of ossification in foot bones of rat fetuses induced by cyclophosphamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217573"} {"pmid": "4217574", "title": "Synthesis of alpha-functional nitrosamines.", "content": "Synthesis of alpha-functional nitrosamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217574"} {"pmid": "4217575", "title": "Dinitrogen(octaethylprophinato)tetrahydrofuranosmium(II): a nitrogen-carrying metalloporphyrin.", "content": "Dinitrogen(octaethylprophinato)tetrahydrofuranosmium(II): a nitrogen-carrying metalloporphyrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217575"} {"pmid": "4217576", "title": "Purification and immunological quantification of human pancreatic lipase.", "content": "Purification and immunological quantification of human pancreatic lipase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217576"} {"pmid": "4217577", "title": "The effect of high salt concentrations upon cytochrome C, cytochrome B5, and iron-EDTA reductase activities of liver microsomal NADPH-cytochrome C reductase.", "content": "The effect of high salt concentrations upon cytochrome C, cytochrome B5, and iron-EDTA reductase activities of liver microsomal NADPH-cytochrome C reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217577"} {"pmid": "4217578", "title": "Practolol in angina pectoris: a double-blind ergometric study.", "content": "Practolol in angina pectoris: a double-blind ergometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217578"} {"pmid": "4217580", "title": "Penicillin-resistant mechanisms in Pseudomonas aeruginosa: effects of penicillin G and carbenicillin on transpeptidase and C -alanine carboxypeptidase activities.", "content": "Penicillin-resistant mechanisms in Pseudomonas aeruginosa: effects of penicillin G and carbenicillin on transpeptidase and C -alanine carboxypeptidase activities. A membrane fraction from Pseudomonas aeruginosa KM 338 was shown to catalyze in vitro peptidoglycan synthesis from uridine 5'-diphosphate-N-acetylmuramyl-l-alanyl-d- glutamyl-meso-diaminopimelyl-d-alanyl-d-alanine and uridine 5'-diphosphate-N-acetylglucosamine. Synthesized peptidoglycan was partially cross-linked by transpeptidation, which was accompanied by the release of d-alanine. This reaction was strongly inhibited by 25 and 50 mug of penicillin G and carbenicillin per ml respectively, whereas the intact cells were relatively resistant to penicillins (minimal inhibitory concentration of penicillin G and carbenicillin, 30 and 0.125 mg/ml, respectively). Soluble d-alanine carboxypeptidase present in P. aeruginosa KM 338 was studied as well, which was found almost completely inhibited by penicillin G and carbenicillin (10 mug/ml).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217580"} {"pmid": "4217581", "title": "Immunogical study of anti-beta-lactamase antibodies by acidimetric methods.", "content": "Immunogical study of anti-beta-lactamase antibodies by acidimetric methods. A beta-lactamase was extracted from an Escherichia coli K-12 strain carrying the R-TEM plasmid and has been purified by affinity chromatography. Antisera to this enzyme were prepared in the rabbit, and the enzyme-antibody neutralization reaction has been evaluated with acidimetric methods (pH stat or pH meter). Under defined experimental conditions, it is now possible to clearly illustrate the enzyme-antibody reaction by means of accurate, rapid, and simple-to-perform methods. These methods are in accord with the specificity of the two reactive partners and allow the detection of the enzyme in a crude bacterial extract which would eventually contain more than one beta-lactamase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217581"} {"pmid": "4217582", "title": "Antimicrobial actions of hexachlorophene: inhibition of respiration in Bacillus megaterium.", "content": "Antimicrobial actions of hexachlorophene: inhibition of respiration in Bacillus megaterium. Hexachlorophene (HCP) inhibits both endogenous and exogenous respiration (oxygen uptake) in Bacillus megaterium, without sparing by any of several substrates. The inhibition is maximal when the cells are treated with 8 mug of HCP per mg of cells (dry weight), which corresponds to the minimal lethal dose. Levels as low as 2 mug/mg are inhibitory but not lethal. HCP also inhibits the respiration of isolated B. megaterium membranes and can act on several components of the electron transport chain in the membranes and on soluble enzymes. Although both forms of nicotinamide adenine dinucleotide, reduced form dehydrogenase and malic dehydrogenase are inhibited by HCP, they are less susceptible than is oxygen uptake. The site of maximal sensitivity is nearer the terminal electron acceptor, but the exact location depends on the cytochrome composition of the membranes. If cytochromes b(1), a, and a(3) are present, but not o, HCP inhibits electron transport on the substrate side of cytochrome b(1); if cytochromes b(1), a(3), and o are present, but not a, the inhibition occurs on the oxygen side of cytochrome b(1). Exogenous menadione, an analogue of menaquinone, reverses the inhibition in both circumstances. The primary lethal action of HCP thus appears to be respiratory inhibition at a site within the membrane-bound part of the electron transport chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217582"} {"pmid": "4217584", "title": "Effects of sublethal concentrations of benzylpenicillin on Pseudomonas aeruginosa.", "content": "Effects of sublethal concentrations of benzylpenicillin on Pseudomonas aeruginosa. Pseudomonas aeruginosa produces a low basal level of beta-lactamase (0.002 to 0.004 IU/mg of protein when benzylpenicillin is used as substrate). The beta-lactamase specific activity can be increased several hundredfold by growing the bacteria in the presence of beta-lactam antibiotics. This induction was studied in Pseudomonas aeruginosa 1822s. The single-cell resistance to benzylpenicillin was 750 mug/ml. In liquid culture all concentrations of benzylpenicillin tested (25 to 2,000 mug/ml) affected the bacteria similarly: beta-lactamase formation was induced, the cells became cholate sensitive, growth rate decreased, filaments were formed, and beta-lactamase was excreted. The effect appeared earlier the higher the concentration of the antibiotic. Most of the effects obtained are concerned with the functioning of the outer membrane. The excretion of beta-lactamase seems to be due to an opening of the periplasmic volume rather than to lysis of the cells. Carbenicillin gave the same effects as benzylpenicillin at the same concentrations; the 10-fold lower resistance to carbenicillin than to benzylpenicillin can be explained by the inability of the inducible beta-lactamase to hydrolyze carbenicillin. The induced beta-lactamase was first cell bound and to a great extent located in the periplasmic volume, but later it was excreted into the medium. This extracellular activity was responsible for the detoxification of the medium. This is analogous to the behavior of gram-positive bacteria rather than to that of Enterobacteriaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217584"} {"pmid": "4217583", "title": "Induction kinetics of beta-lactamase biosynthesis in Pseudomonas aeruginosa.", "content": "Induction kinetics of beta-lactamase biosynthesis in Pseudomonas aeruginosa. The induction of beta-lactamase in Pseudomonas aeruginosa 1822s was studied using benzylpenicillin as inducer. The specific rate of beta-lactamase formation was constant throughout an induction experiment. Above a threshold (20 mug/ml), the specific activity increased linearly with the concentration of the inducer. Removal of the inducer resulted in a rapid cessation of beta-lactamase biosynthesis. Inhibition of protein synthesis by starvation for a required amino acid or by the addition of chloramphenicol also led to an instantaneous arrest in enzyme formation. In the absence of inducer, a basal beta-lactamase activity was formed. The basal and the induced enzymes seem to be identical since they had the same substrate profile, electrophoretic mobility, and molecular weight. In all these respects, induction of beta-lactamase in Pseudomonas aeruginosa is analogous to induction of the lac operon in Escherichia coli. However, there was a long, concentration-dependent lag before beta-lactamase was induced. This can be explained by the outer penetration barrier decreasing the rate of inducer uptake. The lag was significantly shorter for lysozyme-ethylenediaminetetraacetic acid-produced spheroplasts than for intact cells. Induction was obtained with all beta-lactam antibiotics tested, but not with other agents affecting the cell envelope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217583"} {"pmid": "4217585", "title": "Chloroquine-resistant Plasmodium falciparum: effect of substrate on chloroquine and amodiaquin accumulation.", "content": "Chloroquine-resistant Plasmodium falciparum: effect of substrate on chloroquine and amodiaquin accumulation. Glucose stimulates the high-affinity processes of chloroquine and amodiaquin accumulation in owl monkey erythrocytes infected with a chloroquine-susceptible strain of Plasmodium falciparum. Although these erythrocytes have greater ability to accumulate amodiaquin than chloroquine, glucose has relatively less effect on amodiaquin accumulation than on chloroquine accumulation. In contrast to these findings with chloroquine-susceptible P. falciparum, glucose stimulates amodiaquin but not chloroquine accumulation in erythrocytes infected with chloroquine-resistant P. falciparum. This lack of function of a substrate-dependent component of chloroquine accumulation distinguishes chloroquine-resistant from chloroquine-susceptible P. falciparum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217585"} {"pmid": "4217586", "title": "Properties of an R plasmid in Pseudomonas aeruginosa producing amikacin (BB-K8), butirosin, kanamycin, tobramycin, and sisomicin resistance.", "content": "Properties of an R plasmid in Pseudomonas aeruginosa producing amikacin (BB-K8), butirosin, kanamycin, tobramycin, and sisomicin resistance. Pseudomonas aeruginosa strain GN315, producing kanamycin acetyltransferase, can transmit a plasmid determining resistance to kanamycin, amikacin (BB-K8), butirosin, tobramycin, and sisomicin, but not gentamicin, to other pseudomonas strains. This plasmid, pMG5, belongs to the same incompatibility group as plasmids determining gentamicin resistance in P. aeruginosa via gentamicin acetyltransferase I. Like other members of this group, it also confers resistance to Hg(2+), organomercurials, and certain deoxyribonucleic acid phages. When pMG5 is introduced into a cell carrying a related R factor, some transconjugants can subsequently cotransfer new combinations of resistance determinants as though recombinant plasmids had been formed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217586"} {"pmid": "4217587", "title": "Penicillin: reversible inhibition of forespore septum development in Bacillus megaterium cells.", "content": "Penicillin: reversible inhibition of forespore septum development in Bacillus megaterium cells. Benzylpenicillin inhibits the development of the forespore septum in sporulating Bacillus megaterium cells. The inhibitory effect is a function of the duration of exposure to the antibiotic and is completely reversible by penicillinase. Under the incubation conditions employed, less than 20% of the covalently bound antibiotic is released from the cells. The penicillin which remains bound to the cells after treatment with penicillinase may be necessary but is not sufficient for the effect; unbound antibiotic in the sporulation medium is also required.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217587"} {"pmid": "4217588", "title": "Ecological application of antibiotics as respiratory inhibitors of bacterial populations.", "content": "Ecological application of antibiotics as respiratory inhibitors of bacterial populations. Two terregenous and four marine bacterial isolates were treated with six antibiotics and antibiotic combinations. Comparisons made between responses of cells in early and late logarithmic and stationary growth phases indicated variable sensitivity to the agents. Bacteria in stationary and late log-phase cultures exhibited the greatest resistance, whereas the early log-phase cells exhibited greatest antibiotic susceptibility. We conclude that the tested antibiotics cannot be used for ecological purposes to delineate bacterial respiration in mixed microbial communities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217588"} {"pmid": "4217589", "title": "Antagonism of lactic streptococci toward Staphylococcus aureus in associative milk cutures.", "content": "Antagonism of lactic streptococci toward Staphylococcus aureus in associative milk cutures. The inhibition of growth of Staphylococcus aureus by lactic streptococci in associative cultures in milk was not due to hydrogen peroxide produced by the streptococci. Dialyzed whey from the milk culture of lactic streptococci was more inhibitory than dialyzed whey from milk acidified with lactic acid, indicating that material other than lactate was also involved. Analyses of cation and anion exchange fractions from the dialyzed whey showed that only the neutral fraction was inhibitory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217589"} {"pmid": "4217590", "title": "Detecting the enterotoxigenicity of Staphylococcus aureus strains.", "content": "Detecting the enterotoxigenicity of Staphylococcus aureus strains. An optimal sensitivity plate method for examining large number of staphylococcal strains for production of the known enterotoxins (A-E) is presented. Small volumes of relatively concentrated enterotoxin are produced by the semi-solid agar, cellophane-over-agar, or sac culture techniques. Detection of the enterotoxin in the supernatant fluid is accomplished with the optimal sensitivity plate method. In this method small plastic petri dishes (50 mm) were used for a modified Ouchterlony of high sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217590"} {"pmid": "4217591", "title": "Agricultural plants and soil as a reservoir for Pseudomonas aeruginosa.", "content": "Agricultural plants and soil as a reservoir for Pseudomonas aeruginosa. Pseudomonas aeruginosa was detected in 24% of the soil samples but in only 0.13% of the vegetable samples from various agricultural areas of California. The distribution of pyocin types of soil and vegetable isolates was similar to that of clinical strains, and three of the soil isolates were resistant to carbenicillin. Pseudomonas aeruginosa multiplied in lettuce and bean under conditions of high temperature and high relative humidity (27 C and 80-95% relative humidity) but declined when the temperature and humidity were lowered (16 C, 55-75% relative humidity). The results suggest that soil is a reservior for P. aeruginosa and that the bacterium has the capacity to colonize plants during favorable conditions of temperature and moisture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217591"} {"pmid": "4217592", "title": "IgE levels in sera of patients with pemphigus or bullous pemphigoid.", "content": "IgE levels in sera of patients with pemphigus or bullous pemphigoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217592"} {"pmid": "4217593", "title": "Circulatory responses to bacterial cardio-stimulating substances in hemorrhagic dogs.", "content": "Circulatory responses to bacterial cardio-stimulating substances in hemorrhagic dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217593"} {"pmid": "4217595", "title": "Studies on the cell cycle of Myxobacter AL-1. I. Size fractionation of exponentially growing cells by zonal centrifugation.", "content": "Studies on the cell cycle of Myxobacter AL-1. I. Size fractionation of exponentially growing cells by zonal centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217595"} {"pmid": "4217596", "title": "Freeze-etching of the outer membranes of Pseudomonas and Acinetobacter.", "content": "Freeze-etching of the outer membranes of Pseudomonas and Acinetobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217596"} {"pmid": "4217606", "title": "Positive reaction between australia antigen and anti-human liver antibody.", "content": "Positive reaction between australia antigen and anti-human liver antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217606"} {"pmid": "4217607", "title": "Herpesvirus--a possible cause of low fertility in male turkeys.", "content": "Herpesvirus--a possible cause of low fertility in male turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217607"} {"pmid": "4217608", "title": "Serum concentration of pregnancy-specific beta-1-glycoprotein (sp-1) in normal and pathologic pregnancies.", "content": "Serum concentration of pregnancy-specific beta-1-glycoprotein (sp-1) in normal and pathologic pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217608"} {"pmid": "4217611", "title": "Antibacterial action of complexing compounds. II. Influence of disodium ethylendiaminetetraacetate (NA2EDTA) on experimental infection with Pseudomonas aeruginosa in mice.", "content": "Antibacterial action of complexing compounds. II. Influence of disodium ethylendiaminetetraacetate (NA2EDTA) on experimental infection with Pseudomonas aeruginosa in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217611"} {"pmid": "4217612", "title": "Effects of medium chain triglycerides on plasma free fatty acids in normal subjects.", "content": "Effects of medium chain triglycerides on plasma free fatty acids in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217612"} {"pmid": "4217613", "title": "Annual directory. Membership roster. Arkansas State Dental Association.", "content": "Annual directory. Membership roster. Arkansas State Dental Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217613"} {"pmid": "4217614", "title": "Clinical use of some dental materials composite restorative materials.", "content": "Clinical use of some dental materials composite restorative materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217614"} {"pmid": "4217615", "title": "Editorial: Two threats to survival.", "content": "Editorial: Two threats to survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217615"} {"pmid": "4217619", "title": "Collagen turnover in the gingiva and other mature connective tissues of the marmoset Saguinus oedipus.", "content": "Collagen turnover in the gingiva and other mature connective tissues of the marmoset Saguinus oedipus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217619"} {"pmid": "4217620", "title": "Growth of Streptococcus mutans in a chemostat.", "content": "Growth of Streptococcus mutans in a chemostat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217620"} {"pmid": "4217622", "title": "Life times: Alice Muller.", "content": "Life times: Alice Muller.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217622"} {"pmid": "4217621", "title": "Human parotid IgA and periodontal disease.", "content": "Human parotid IgA and periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217621"} {"pmid": "4217623", "title": "The use of esophageal motility studies in the diagnosis of dysphagia.", "content": "The use of esophageal motility studies in the diagnosis of dysphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217623"} {"pmid": "4217624", "title": "Some difficulties in the treatment of dysphagia in adults.", "content": "Some difficulties in the treatment of dysphagia in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217624"} {"pmid": "4217625", "title": "Cidex-sterilising solution chemical.", "content": "Cidex-sterilising solution chemical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217625"} {"pmid": "4217626", "title": "The hippocampus and contextual retrieval of information from memory: a theory.", "content": "The hippocampus and contextual retrieval of information from memory: a theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217626"} {"pmid": "4217628", "title": "Mitochondrial and cytoplasmic ribosomes. Distinguishing characteristics and a requirement for the homologous ribosomal salt-extractable fraction for protein synthesis.", "content": "Mitochondrial and cytoplasmic ribosomes. Distinguishing characteristics and a requirement for the homologous ribosomal salt-extractable fraction for protein synthesis. 1. Mitochondrial and cytoplasmic ribosomes of Euglena gracilis differ in their total RNA and protein content. 2. Mitochondrial ribosomes dissociate to subunits at higher Mg(2+) concentrations than do cytoplasmic ribosomes. 3. A separable 5S RNA is obtained from cytoplasmic and chloroplast ribosomes, but not from mitochondrial ribosomes. 4. For protein-synthesizing activity with a natural mRNA, mitochondrial ribosomes use tRNA from any cell compartment and are partly active with supernatant enzymes from cytoplasm. Cytoplasmic ribosomes are partly active with enzymes and tRNA from mitochondria or chloroplasts. 5. Both mitochondrial and cytoplasmic ribosomes show high specificity for the homologous salt-extractable ribosomal fraction for protein-synthesizing activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217628"} {"pmid": "4217629", "title": "Pseudoperoxidase activity of mushroom tyrosinase.", "content": "Pseudoperoxidase activity of mushroom tyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217629"} {"pmid": "4217631", "title": "The effects of anti-arthritic gold compounds on mycoplasma and leishmania.", "content": "The effects of anti-arthritic gold compounds on mycoplasma and leishmania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217631"} {"pmid": "4217632", "title": "Anthelminthic efficacy of diospyrol and its derivatives.", "content": "Anthelminthic efficacy of diospyrol and its derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217632"} {"pmid": "4217634", "title": "Central haemodynamics during spontaneous angina pectoris.", "content": "Central haemodynamics during spontaneous angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217634"} {"pmid": "4217635", "title": "Studies on the pathogenesis of experimental chronic active hepatitis in rabbits. II. Demonstration of immunoglobulin on isolated hepatocytes.", "content": "Studies on the pathogenesis of experimental chronic active hepatitis in rabbits. II. Demonstration of immunoglobulin on isolated hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217635"} {"pmid": "4217636", "title": "Parenteral nutrition.", "content": "Parenteral nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217636"} {"pmid": "4217637", "title": "The hyperviscosity syndrome.", "content": "The hyperviscosity syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217637"} {"pmid": "4217638", "title": "Effect of ferrous ions on microsomal phospholipid peroxidation and related light emission.", "content": "Effect of ferrous ions on microsomal phospholipid peroxidation and related light emission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217638"} {"pmid": "4217639", "title": "Partial specific volume and molecular weight determinations from sedimentation equilibrium experiments in H2O and H2-18O. Study of an immunomacroglobulin type lambda, (IgM) Lambda.", "content": "Partial specific volume and molecular weight determinations from sedimentation equilibrium experiments in H2O and H2-18O. Study of an immunomacroglobulin type lambda, (IgM) Lambda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217639"} {"pmid": "4217640", "title": "Supplementary feeding during the preweaning period. Effect on carcass composition and adipose tissue cellularity of the rat.", "content": "Supplementary feeding during the preweaning period. Effect on carcass composition and adipose tissue cellularity of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217640"} {"pmid": "4217641", "title": "Evolution of titre of serum IgG in newborn.", "content": "Evolution of titre of serum IgG in newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217641"} {"pmid": "4217642", "title": "Proceedings: Effect of cromoglycate and eicosatetraynoic acid on the release of prostaglandins and SRS-a from immunologically challenged guinea pig lungs.", "content": "Proceedings: Effect of cromoglycate and eicosatetraynoic acid on the release of prostaglandins and SRS-a from immunologically challenged guinea pig lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217642"} {"pmid": "4217643", "title": "Effects of dipyridamole on neurogenic and non-neurogenic dilator responses of arterial smooth muscle.", "content": "Effects of dipyridamole on neurogenic and non-neurogenic dilator responses of arterial smooth muscle. 1 In the isolated, perfused parametrial artery of the guinea-pig dipyridamole (10-100 ng/ml) potentiated dilator responses to adenosine 5'-triphosphate (ATP), glyceryl trinitrate and non-cholinergic, non-adrenergic inhibitory nerve stimulation to similar extents. In contrast dilator responses to acetylcholine were generally unaffected or reduced.2 These results support previous electro-physiological evidence that in this preparation cholinergic vasodilatation is mediated by a cellular mechanism different from that involved in the response to non-cholinergic dilator nervous activation.3 The results also suggest that potentiation of a neurally-mediated inhibitory response of smooth muscle by dipyridamole does not necessarily implicate ATP as the transmitter involved in this response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217643"} {"pmid": "4217644", "title": "Experience with treatment of primary malignant disease of the prostate by localised external supervoltage irradiation using cobalt-60 or high energy electrons.", "content": "Experience with treatment of primary malignant disease of the prostate by localised external supervoltage irradiation using cobalt-60 or high energy electrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217644"} {"pmid": "4217645", "title": "Serological investigations on endotoxins isolated from Sphaerophorus funduliformis (syn. Fusobacterium necrophorum) strains.", "content": "Serological investigations on endotoxins isolated from Sphaerophorus funduliformis (syn. Fusobacterium necrophorum) strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217645"} {"pmid": "4217646", "title": "Comparative immunochemical studies on the endotoxins of two Fusobacterium necrophorum strains.", "content": "Comparative immunochemical studies on the endotoxins of two Fusobacterium necrophorum strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217646"} {"pmid": "4217649", "title": "Chemistry of the renal reabsorption of bicarbonate.", "content": "Chemistry of the renal reabsorption of bicarbonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217649"} {"pmid": "4217650", "title": "Turnover and metabolism of polychlorinated biphenyls in relation to their chemical structure and the movement of lipids in the pigeon.", "content": "Turnover and metabolism of polychlorinated biphenyls in relation to their chemical structure and the movement of lipids in the pigeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217650"} {"pmid": "4217654", "title": "A differential effect of IgM and IgG antibodies on the blastogenic response of lymphocytes to rubella virus.", "content": "A differential effect of IgM and IgG antibodies on the blastogenic response of lymphocytes to rubella virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217654"} {"pmid": "4217655", "title": "Studies on antigenic competition. Efforts to identify the cellular basis of competition using a cell transfer system.", "content": "Studies on antigenic competition. Efforts to identify the cellular basis of competition using a cell transfer system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217655"} {"pmid": "4217656", "title": "Surface immunoglobulin of mouse thymus cells and its in vitro biosynthesis.", "content": "Surface immunoglobulin of mouse thymus cells and its in vitro biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217656"} {"pmid": "4217657", "title": "Effect of thymus cell injections on germinal center formation in lymphoid tissues of nude (thymusless) mice.", "content": "Effect of thymus cell injections on germinal center formation in lymphoid tissues of nude (thymusless) mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217657"} {"pmid": "4217660", "title": "Studies on kallikreins. III. Intra-intestinal administration of hog pancreatic kallikrein and its appearance in the perfusate from the mesenteric vein.", "content": "Studies on kallikreins. III. Intra-intestinal administration of hog pancreatic kallikrein and its appearance in the perfusate from the mesenteric vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217660"} {"pmid": "4217661", "title": "The chemistry and control of hereditary lipid diseases.", "content": "The chemistry and control of hereditary lipid diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217661"} {"pmid": "4217662", "title": "The properties of alpha-galactosidase remaining in kidney and liver of patients with Fabry's disease.", "content": "The properties of alpha-galactosidase remaining in kidney and liver of patients with Fabry's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217662"} {"pmid": "4217676", "title": "Diseases of the hypothalamus and pituitary gland.", "content": "Diseases of the hypothalamus and pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217676"} {"pmid": "4217677", "title": "Evidence for the activation of complement via the alternate pathway in skin diseases. II. Dermatitis herpetiformis.", "content": "Evidence for the activation of complement via the alternate pathway in skin diseases. II. Dermatitis herpetiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217677"} {"pmid": "4217678", "title": "A human monoclonal IgM with binding activity for C-reactive protein (CRP).", "content": "A human monoclonal IgM with binding activity for C-reactive protein (CRP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217678"} {"pmid": "4217679", "title": "The interaction of lupus-inducing drugs with deoxyribonucleic acid.", "content": "The interaction of lupus-inducing drugs with deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217679"} {"pmid": "4217680", "title": "A review: The obese strain (OS) of chickens: an animal model with spontaneous autoimmune thyroiditis.", "content": "A review: The obese strain (OS) of chickens: an animal model with spontaneous autoimmune thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217680"} {"pmid": "4217682", "title": "Larval-specific serum protein in the order Dictyoptera I. Immunologic characterization in larval Blattella germanica and cross-reaction throughout the order.", "content": "Larval-specific serum protein in the order Dictyoptera I. Immunologic characterization in larval Blattella germanica and cross-reaction throughout the order.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217682"} {"pmid": "4217681", "title": "Chemical composition of the cuticle, and the inner and outer shell membranes from eggs of Gallus gallus.", "content": "Chemical composition of the cuticle, and the inner and outer shell membranes from eggs of Gallus gallus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217681"} {"pmid": "4217684", "title": "Predicting the stabilities of freeze-dried suspensions of Lactobacillus acidophilus by the accelerated storage test.", "content": "Predicting the stabilities of freeze-dried suspensions of Lactobacillus acidophilus by the accelerated storage test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217684"} {"pmid": "4217683", "title": "Disorders of the autonomic nervous system. Chapter 14. The alimentary tract.", "content": "Disorders of the autonomic nervous system. Chapter 14. The alimentary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217683"} {"pmid": "4217685", "title": "Cryosurgery of the rabbit prostate. Comparison of the immune response of immature and mature bucks.", "content": "Cryosurgery of the rabbit prostate. Comparison of the immune response of immature and mature bucks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217685"} {"pmid": "4217686", "title": "The effect of abrupt changes in sodium chloride concentration upon the viability of gram-negative bacteria at 2 and 40 degrees C.", "content": "The effect of abrupt changes in sodium chloride concentration upon the viability of gram-negative bacteria at 2 and 40 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217686"} {"pmid": "4217687", "title": "Child abuse: one tree in the forest.", "content": "Child abuse: one tree in the forest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217687"} {"pmid": "4217689", "title": "Epilepsy due to cerebral cysticercosis.", "content": "Epilepsy due to cerebral cysticercosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217689"} {"pmid": "4217690", "title": "Childhood epileptic encephalopathy with slow spike-wave. A statistical study of 80 cases.", "content": "Childhood epileptic encephalopathy with slow spike-wave. A statistical study of 80 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217690"} {"pmid": "4217691", "title": "Pharmacoligic prophylaxis of posttraumatic epilepsy. A review.", "content": "Pharmacoligic prophylaxis of posttraumatic epilepsy. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217691"} {"pmid": "4217692", "title": "Epilepsy with multiple sclerosis.", "content": "Epilepsy with multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217692"} {"pmid": "4217693", "title": "Proceedings: Responsiveness at the onset of spike-wave bursts.", "content": "Proceedings: Responsiveness at the onset of spike-wave bursts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217693"} {"pmid": "4217694", "title": "Proceedings: A multifactorial analysis of focal and generalized cortico-reticular (centrencephalic) epilepsy.", "content": "Proceedings: A multifactorial analysis of focal and generalized cortico-reticular (centrencephalic) epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217694"} {"pmid": "4217695", "title": "Proceedings: Focal spikes in childhood and the concept of \"functional\" spike activity.", "content": "Proceedings: Focal spikes in childhood and the concept of \"functional\" spike activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217695"} {"pmid": "4217696", "title": "Proceedings: Long-term follow-up of children with grand mal seizures.", "content": "Proceedings: Long-term follow-up of children with grand mal seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217696"} {"pmid": "4217697", "title": "Interaction between beta-lactam antibiotics and exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61.", "content": "Interaction between beta-lactam antibiotics and exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217697"} {"pmid": "4217734", "title": "The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro.", "content": "The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217734"} {"pmid": "4217735", "title": "The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro.", "content": "The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217735"} {"pmid": "4217736", "title": "The treatment of lactic acidosis in the diabetic patient by peritoneal dialysis using sodium acetate. A report of two cases.", "content": "The treatment of lactic acidosis in the diabetic patient by peritoneal dialysis using sodium acetate. A report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217736"} {"pmid": "4217738", "title": "Leucine tolerance in protein-calorie malnutrition.", "content": "Leucine tolerance in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217738"} {"pmid": "4217739", "title": "Nasogastric tube feeding.", "content": "Nasogastric tube feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217739"} {"pmid": "4217740", "title": "Lactose absorption in protein-calorie malnutrition.", "content": "Lactose absorption in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217740"} {"pmid": "4217742", "title": "The glycogenolytic activity in protein-calorie malnutrition.", "content": "The glycogenolytic activity in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217742"} {"pmid": "4217741", "title": "Classification and epidemiology of protein-calorie malnutrition.", "content": "Classification and epidemiology of protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217741"} {"pmid": "4217743", "title": "Dietary faults in health and disease leading to protein-calorie malnutrition.", "content": "Dietary faults in health and disease leading to protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217743"} {"pmid": "4217744", "title": "Parenteral feeding.", "content": "Parenteral feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217744"} {"pmid": "4217745", "title": "Treatment of protein--calorie malnutrition using a protein rich food (AN-68) based on \"Bellila dish\".", "content": "Treatment of protein--calorie malnutrition using a protein rich food (AN-68) based on \"Bellila dish\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217745"} {"pmid": "4217747", "title": "Positive selection for mating with functional heterokaryons in Tetrahymena pyriformis.", "content": "Positive selection for mating with functional heterokaryons in Tetrahymena pyriformis. Allelic assortment of Tetrahymena pyriformis makes possible the isolation of cells which contain both a heterozygous germ line nucleus and a somatic nucleus which expresses phenotypes of only one member of allelic pairs. Cycloheximide-sensitive segregants have been isolated from the vegetative progeny of cells heterozygous for a dominant mutation conferring resistance to cycloheximide; such segregants are called functional heterokaryons. Since progeny from crosses of these cells are cycloheximide-resistant, addition of the drug provides positive selection for successful exconjugants. The timing for expression of the new phenotype during conjugation is presented and used to identify what appear to be immature progeny of round one mating in genomic exclusion. Usefulness of functional heterokaryons in a number of genetic and developmental studies is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217747"} {"pmid": "4217746", "title": "Histologic identification and immunochemical studies of prolactin and growth hormone in the primate pituitary gland.", "content": "Histologic identification and immunochemical studies of prolactin and growth hormone in the primate pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217746"} {"pmid": "4217748", "title": "Genetic limits of the xanthine dehydrogenase structural element within the rosy locus in Drosophila melanogaster.", "content": "Genetic limits of the xanthine dehydrogenase structural element within the rosy locus in Drosophila melanogaster. Experiments are described that provide an opportunity to estimate the genetic limits of the structural (amino acid coding) portion of the rosy locus (3:52.0) in Drosophila melanogaster, which controls the enzyme, xanthine dehydrogenase (XDH). This is accomplished by mapping experiments which localize sites responsible for electrophoretic variation in the enzyme on the known genetic map of null-XDH rosy mutants. Electrophoretic sites are distributed along a large portion of the null mutant map. A cis-trans test involving electrophoretic variants in the left- and right-hand portions of the map leads to the conclusion that the entire region between these variants is also structural. Hence most, if not all, of the null mutant map of the rosy locus contains structural information for the amino acid sequence of the XDH polypeptide. Consideration is given to the significance of the present results for the general problem of gene organization in higher eukaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217748"} {"pmid": "4217749", "title": "Ribosomal gene magnification in Drosophila: a chromosomal change.", "content": "Ribosomal gene magnification in Drosophila: a chromosomal change. The sex-linked mutant \"bobbed\" can undergo a rapid phenotypic reversion during a prescribed series of outcrosses. The experiments reported here distinguish between two general genetic models. The first is that the phenotypic change results from the changing genetic background brought about by the outcrosses. The second is that the phenotypic change results from an alteration of the X chromosome in the germ line. The data support the second model. It is shown that both the bobbed and reverted phenotypes segregate from the same female. In addition, the reverted phenotype maps in or near the proximal heterochromatin of the X chromosome, which is the standard map position of both bobbed and the nucleolus organizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217749"} {"pmid": "4217751", "title": "The direction of linkage disequilibrium.", "content": "The direction of linkage disequilibrium. The previous paper (Langley, Tobari and Kojima 1974) reports that the directional linkage disequilibria, D(omega) = P(AB)P(ab)-P(Ab)P(aB), tend to be negative for data between allozymes and linked to inversions. A and B stand for the two alleles with the greatest frequency in the population. In this paper we show that linkage disequilibrium in this direction is produced at equilibrium when double homozygotes have fitnesses that are a constant fraction of the product of the two component single homozygote fitnesses, a pattern that is frequently observed in experimental data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217751"} {"pmid": "4217750", "title": "Linkage disequilibrium in natural populations of Drosophila melanogaster.", "content": "Linkage disequilibrium in natural populations of Drosophila melanogaster. Two large, stable populations (Texas and Japan) of Drosophila melanogaster were surveyed at 21 allozyme loci on the second and third chromosomes and for chromosomal gene arrangements on those two chromosomes. Over 220 independent gametes were sampled from each population. The types and frequencies of the surveyed genetic variation are similar to those observed previously and suggest only slight differentiation among geographically distant populations. Linkage disequilibrium among linked allozymes loci is only slightly, if at all, detectable with these sample sizes. Linkage disequilibrium between linked inversions and allozymes loci is common especially when located in the same arm. These disequilibria appear to be in the same direction for most comparisons in the two population samples. This result is interpreted as evidence of similar selective environments (ecological and genetic) in the two populations. It is also noted that the direction of these linkage disequilibria appears to be oriented with respect to the gene frequencies at the component loci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217750"} {"pmid": "4217752", "title": "Population structure in artificial selection: studies with Drosophila melanogaster.", "content": "Population structure in artificial selection: studies with Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217752"} {"pmid": "4217753", "title": "Genetic analysis of larval feeding behaviour in Drosophila melanogaster.", "content": "Genetic analysis of larval feeding behaviour in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217753"} {"pmid": "4217754", "title": "Physiological genetics of melantoic tumours in Drosophila melanogaster. VIII. The role of choline in the expression of the tumor gene tu bw and of its suppressor, su-tu.", "content": "Physiological genetics of melantoic tumours in Drosophila melanogaster. VIII. The role of choline in the expression of the tumor gene tu bw and of its suppressor, su-tu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217754"} {"pmid": "4217755", "title": "The mode of attachment and relation to the host in Apiosoma piscicola Blanchard and Epistylis lwoffi Fauré-Fremiet, ectocommensals of freshwater fish.", "content": "The mode of attachment and relation to the host in Apiosoma piscicola Blanchard and Epistylis lwoffi Fauré-Fremiet, ectocommensals of freshwater fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217755"} {"pmid": "4217756", "title": "Thyrotropin responses to TRH in depressive illness: relation to clinical subtypes and prolonged duration of depressive episode.", "content": "Thyrotropin responses to TRH in depressive illness: relation to clinical subtypes and prolonged duration of depressive episode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217756"} {"pmid": "4217757", "title": "Investigations on the antilipolytic activity of sulfonylureas in man with indications on limit dosages concerning their insulin-secreting properties.", "content": "Investigations on the antilipolytic activity of sulfonylureas in man with indications on limit dosages concerning their insulin-secreting properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217757"} {"pmid": "4217758", "title": "Impaired prolactin response to synthetic thyrotropin-releasing hormone after a 36 hour fast.", "content": "Impaired prolactin response to synthetic thyrotropin-releasing hormone after a 36 hour fast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217758"} {"pmid": "4217759", "title": "The effect of thyrotrophin-releasing hormone on serum TSH, T-4, and T-3 levels in endemic and sporadic nontoxic goitre.", "content": "The effect of thyrotrophin-releasing hormone on serum TSH, T-4, and T-3 levels in endemic and sporadic nontoxic goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217759"} {"pmid": "4217760", "title": "Effect of the antiestrogen nafoxidine on the occurrence of estrogen-dependent renal tumors in hamster.", "content": "Effect of the antiestrogen nafoxidine on the occurrence of estrogen-dependent renal tumors in hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217760"} {"pmid": "4217761", "title": "Thyroid hormone levels in adult protein calorie malnutrition (PCM).", "content": "Thyroid hormone levels in adult protein calorie malnutrition (PCM).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217761"} {"pmid": "4217765", "title": "Preparation of a relatively acid-stable antigen (CEA) by disruption of its specific precipitate with antibody.", "content": "Preparation of a relatively acid-stable antigen (CEA) by disruption of its specific precipitate with antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217765"} {"pmid": "4217766", "title": "Production of antibodies to carcinoembryonic antigen in tolerant rabbits.", "content": "Production of antibodies to carcinoembryonic antigen in tolerant rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217766"} {"pmid": "4217767", "title": "The cardiac autoimmune system. VII. Heart specific auto-antibodies produced in rabbits immunized with human heart.", "content": "The cardiac autoimmune system. VII. Heart specific auto-antibodies produced in rabbits immunized with human heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217767"} {"pmid": "4217768", "title": "A method for assessing the in vitro chemotactic response of neutrophils utilizing 51cr-labeled human leukocytes.", "content": "A method for assessing the in vitro chemotactic response of neutrophils utilizing 51cr-labeled human leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217768"} {"pmid": "4217769", "title": "Method of quick detection of antigen-antibody precipitin reaction.", "content": "Method of quick detection of antigen-antibody precipitin reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217769"} {"pmid": "4217762", "title": "Use of papain in the preparation of adult mammalian skeletal muscle for tissue culture.", "content": "Use of papain in the preparation of adult mammalian skeletal muscle for tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217762"} {"pmid": "4217770", "title": "Anti-SRBC plaque-forming cells in liver, spleen and hepatocyte cell suspensions of rabbits and mice.", "content": "Anti-SRBC plaque-forming cells in liver, spleen and hepatocyte cell suspensions of rabbits and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217770"} {"pmid": "4217771", "title": "The influence of the shape of phagocytes on their adhesiveness.", "content": "The influence of the shape of phagocytes on their adhesiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217771"} {"pmid": "4217772", "title": "Inhibition of rosette formation by spleen cells of immunized mice by antibodies to aggregated mouse immunoglobulins.", "content": "Inhibition of rosette formation by spleen cells of immunized mice by antibodies to aggregated mouse immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217772"} {"pmid": "4217773", "title": "Characterization of subunits from a reconstituted monoclonal IgM that binds IgG.", "content": "Characterization of subunits from a reconstituted monoclonal IgM that binds IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217773"} {"pmid": "4217774", "title": "Hydrosoluble immunopotentiating substances extraced from Corynebacterium parvum.", "content": "Hydrosoluble immunopotentiating substances extraced from Corynebacterium parvum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217774"} {"pmid": "4217763", "title": "Origin of endogenous and exogenous agents in cell cultures.", "content": "Origin of endogenous and exogenous agents in cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217763"} {"pmid": "4217775", "title": "Leucocyte migration inhibition as a model for the demonstration of sensitized cells in East Coast fever.", "content": "Leucocyte migration inhibition as a model for the demonstration of sensitized cells in East Coast fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217775"} {"pmid": "4217764", "title": "A new method for dispersing strongly adhesive cells in tissue culture.", "content": "A new method for dispersing strongly adhesive cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217764"} {"pmid": "4217776", "title": "Non-covalent association of IgM subunits produced by reduction and alkylation.", "content": "Non-covalent association of IgM subunits produced by reduction and alkylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217776"} {"pmid": "4217777", "title": "A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in immunized volunteers.", "content": "A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in immunized volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217777"} {"pmid": "4217779", "title": "Palyam group: a new serogroup of arboviruses: physicochemical and biological properties of Palyam and Kasba viruses.", "content": "Palyam group: a new serogroup of arboviruses: physicochemical and biological properties of Palyam and Kasba viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217779"} {"pmid": "4217778", "title": "The effect of homologous and heterologous carriers on the immunogenicity of the galactocerebroside hapten.", "content": "The effect of homologous and heterologous carriers on the immunogenicity of the galactocerebroside hapten.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217778"} {"pmid": "4217780", "title": "A psychoanalytic psychotherapy of a patient with cerebral palsy: the relation of aggression to self and body representations.", "content": "A psychoanalytic psychotherapy of a patient with cerebral palsy: the relation of aggression to self and body representations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217780"} {"pmid": "4217781", "title": "Cellular regulation in sexual development.", "content": "Cellular regulation in sexual development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217781"} {"pmid": "4217782", "title": "Evaluation of media used for cultures of Neisseria gonorrhoeae and comparison of commercial and laboratory prepared supplements.", "content": "Evaluation of media used for cultures of Neisseria gonorrhoeae and comparison of commercial and laboratory prepared supplements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217782"} {"pmid": "4217783", "title": "Microepidemic of virulent gonococcal infection.", "content": "Microepidemic of virulent gonococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217783"} {"pmid": "4217784", "title": "Criteria for cure of gonorrhea. How reliable are they?", "content": "Criteria for cure of gonorrhea. How reliable are they?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217784"} {"pmid": "4217785", "title": "Evaluation of self-obtained cultures using a vaginal tampon as a method of screening for asymptomatic gonorrhea on a college campus.", "content": "Evaluation of self-obtained cultures using a vaginal tampon as a method of screening for asymptomatic gonorrhea on a college campus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217785"} {"pmid": "4217786", "title": "Steffimycin B, a new member of the steffimycin family: isolation and characterization.", "content": "Steffimycin B, a new member of the steffimycin family: isolation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217786"} {"pmid": "4217787", "title": "Microbial production of vitamin B12 antimetabolites. I. N5-hydroxy-L-arginine from Bacillus cereus 439.", "content": "Microbial production of vitamin B12 antimetabolites. I. N5-hydroxy-L-arginine from Bacillus cereus 439.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217787"} {"pmid": "4217788", "title": "Aminoglycoside antibiotics. VII. Synthesis and activity of 4'-deoxykanamycin A.", "content": "Aminoglycoside antibiotics. VII. Synthesis and activity of 4'-deoxykanamycin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217788"} {"pmid": "4217789", "title": "Aminoglycoside antibiotics. IX. 1-N-acyl derivatives of kanamycin A (amikacin analogs).", "content": "Aminoglycoside antibiotics. IX. 1-N-acyl derivatives of kanamycin A (amikacin analogs).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217789"} {"pmid": "4217790", "title": "The mode of action of polyketoacidomycin on Bacillus subtilis.", "content": "The mode of action of polyketoacidomycin on Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217790"} {"pmid": "4217791", "title": "On the mode of action of ASK-753, a new iron-containing antibiotic.", "content": "On the mode of action of ASK-753, a new iron-containing antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217791"} {"pmid": "4217792", "title": "The synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]gentamicin C1 and 1-N-[ (S) -3-amino-2-hydroxypropionyl]gentamicin C1.", "content": "The synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]gentamicin C1 and 1-N-[ (S) -3-amino-2-hydroxypropionyl]gentamicin C1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217792"} {"pmid": "4217793", "title": "Studies on the biosynthesis and morphogenesis of R-type pyocins of Pseudomonas aeruginosa. IV. Quantitative estimation of the rates of synthesis of pyocin R subunit proteins.", "content": "Studies on the biosynthesis and morphogenesis of R-type pyocins of Pseudomonas aeruginosa. IV. Quantitative estimation of the rates of synthesis of pyocin R subunit proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217793"} {"pmid": "4217794", "title": "Phosphoenolpyruvate carboxylating enzyme in dark-grown and in green Euglena cells.", "content": "Phosphoenolpyruvate carboxylating enzyme in dark-grown and in green Euglena cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217794"} {"pmid": "4217795", "title": "Lack of exchange of ribosomal structural proteins with cell-sap proteins of rat liver in vitro.", "content": "Lack of exchange of ribosomal structural proteins with cell-sap proteins of rat liver in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217795"} {"pmid": "4217796", "title": "Inhibition by analogues of the hydrolysis of phenyl alpha-maltoside catalyzed by saccharifying alpha-amylase from Bacillus subtilis.", "content": "Inhibition by analogues of the hydrolysis of phenyl alpha-maltoside catalyzed by saccharifying alpha-amylase from Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217796"} {"pmid": "4217797", "title": "Ectopic ossification following total hip replacement. Incidence and a method of classification.", "content": "Ectopic ossification following total hip replacement. Incidence and a method of classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217797"} {"pmid": "4217798", "title": "Rickets, osteomalacia, and renal osteodystrophy. Part II.", "content": "Rickets, osteomalacia, and renal osteodystrophy. Part II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217798"} {"pmid": "4217800", "title": "Glutaraldehyde fixation of isolated eucaryotic nuclei. Evidence for histone-histone proximity.", "content": "Glutaraldehyde fixation of isolated eucaryotic nuclei. Evidence for histone-histone proximity. Isolated chicken erythrocyte nuclei have been incubated with dilute concentrations of the bifunctional cross-linking agent glutaraldehyde (0-20 mM) in order to stabilize histone-histone interactions within the native nucleus. The kinetics of the disappearance of acid-soluble histones, free amino groups, and of individual histones have been observed to be pseudo first-order. Apparent first-order rate constants for the disappearance of individual histones correlate with the lysine mole percent of that fraction and follow the ranking, k(app): F1 > F2C > F2B >/= F2A2, F2A1, F3. Histone polymers were observed to form very rapidly during the fixation reaction. Partial fractionation and amino acid analyses of these polymers support the view that they are composed principally of cross-linked (F2C)(n) molecules (where n = 2 to approximately 8). The rate of glutaraldehyde reaction with free amino groups in histones is drastically reduced in solvents that promote chromatin decondensation (i.e., low ionic strengths in the absence of divalent cations) whereas the formation of cross-linked F2C polymers is less severely reduced. It is proposed that some F2C histones exist in close proximity within the isolated erythrocyte nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217800"} {"pmid": "4217802", "title": "Development of high resolution pyrolysis-gas chromatography for the identification of microorganisms.", "content": "Development of high resolution pyrolysis-gas chromatography for the identification of microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217802"} {"pmid": "4217801", "title": "The synthesis and turnover of rat liver of rat liver peroxisomes. IV. Biochemical pathway of catalase synthesis.", "content": "The synthesis and turnover of rat liver of rat liver peroxisomes. IV. Biochemical pathway of catalase synthesis. Early events in the biosynthesis of liver catalase were studied on female rats receiving [(3)H]leucine or [(3)H]delta-aminolevulinic acid or a mixture of [(3)H]leucine with [(14)C]delta-aminolevulinic acid by intraportal injection. Catalase antigen was selectively separated from homogenates by immunoprecipitation, both without and after partial purification of the enzyme. Label from both precursors appeared first in immunoprecipitable material which was lost upon purification of catalase; the label subsequently became associated with material indistinguishable from catalase. Kinetic analysis of the results indicates that the nonpurifiable material identified by early labeling consists of two distinct biosynthetic intermediates, the first lacking heme and representing about 1.6% of the total catalase content or 13 microg/g liver, the second containing heme and representing about 0.5% of the total catalase content or 4 microg/g liver. The first intermediate migrates at the same rate as catalase upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and therefore has a monomeric molecular weight of about 60,000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217801"} {"pmid": "4217804", "title": "The pre-albumin fraction: a useful parameter in the interpretation of routine protein electrophoresis.", "content": "The pre-albumin fraction: a useful parameter in the interpretation of routine protein electrophoresis. A technique of protein electrophoresis suitable for routine use which ensures good separation of the prealbumin fraction is described. The clinical value of visually estimating this protein fraction from the electrophoretic strip is shown with reference to 134 cases. Low levels of prealbumin were found to be associated with liver disorders, malignancy, collagen diseases, congestive cardiac failure, and burns. Finally, pitfalls in electrophoretic technique which may cause failure to visualize the prealbumin fraction are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217804"} {"pmid": "4217803", "title": "The effect of age upon the coagulation system.", "content": "The effect of age upon the coagulation system. Factors V, VII, VIII, X, XI, and XII of the coagulation system, platelet count, and antithrombin III levels were assayed in 20 healthy volunteers aged 20-40 years and 61 elderly subjects aged 66-96 years whose skinfold thickness was also measured. Factors XI, XII, and antithrombin III levels tended to increase in women and decrease in men while factors X, VII, and V tended to increase in both males and females with advancing years. No age or sex differences were found in platelet counts or factor VIII levels. Factor VIII levels were inversely correlated with obesity in elderly males (r = -0.56, p < 0.005).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217803"} {"pmid": "4217806", "title": "Chlorhexidine in dental practice.", "content": "Chlorhexidine in dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217806"} {"pmid": "4217805", "title": "Bacterial flora of the appendix fossa in appendicitis and postoperative wound infection.", "content": "Bacterial flora of the appendix fossa in appendicitis and postoperative wound infection. Bacteria were isolated from 153 (47.5%) swabs of the appendix fossa in 322 patients undergoing appendicectomy. The commonest organism was Bacteroides species found in 78% of specimens. Other Gram-negative bacilli such as Klebsiella, or Enterobacter, and Esch. coli were present in 29 and 27% respectively. Gram-positive cocci were less frequently isolated.A positive culture was obtained more commonly in perforated appendicitis (79%) than where chronic fibrosis, lymphoid hyperplasia, or acute appendicitis was present or when the appendix was normal. Bacteroides was isolated twice as often in perforated appendicitis. The incidence of wound infection was 19% and varied according to the state of the appendix, being 63% in perforated appendicitis and 9.5% where lymphoid hyperplasia was present. Bacteroides was isolated from over 90% of the wound infections. In the patients with perforated appendicitis where effective chemotherapy was given the incidence of wound infection was 15% whereas in untreated or inappropriately treated patients it was over 50%. The isolation of bacteroides requires special precautions to be taken both in the collection of the specimen and laboratory culture. It is important that the chemotherapy of postappendicectomy infections include an antibiotic active against bacteroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217805"} {"pmid": "4217807", "title": "Hepatitis-associated antigen in various population groups in Upper Egypt.", "content": "Hepatitis-associated antigen in various population groups in Upper Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217807"} {"pmid": "4217808", "title": "Hepatitis and hepatitis-associated antigen (Au) in Upper Egypt.", "content": "Hepatitis and hepatitis-associated antigen (Au) in Upper Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217808"} {"pmid": "4217809", "title": "Oral management of uncomplicated maturity onset diabetes.", "content": "Oral management of uncomplicated maturity onset diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217809"} {"pmid": "4217810", "title": "Side effects of IV fructose load in diabetics.", "content": "Side effects of IV fructose load in diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217810"} {"pmid": "4217811", "title": "Immunologic relationship between the bactericidal fraction of neurotoxin and the protein from Salmonella typhimurium \"S\" endotoxin.", "content": "Immunologic relationship between the bactericidal fraction of neurotoxin and the protein from Salmonella typhimurium \"S\" endotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217811"} {"pmid": "4217812", "title": "The immunochemical investigations of endotoxins of asporulating gram negative rods (genus Sphaerophorus and Eggerthella).", "content": "The immunochemical investigations of endotoxins of asporulating gram negative rods (genus Sphaerophorus and Eggerthella).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217812"} {"pmid": "4217814", "title": "Fever and sleep cycle changes caused by bacterial products.", "content": "Fever and sleep cycle changes caused by bacterial products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217814"} {"pmid": "4217813", "title": "Immunochemical and toxic properties of the lipopolysaccharides from highly and low virulent Pseudomonas aeruginosa strains.", "content": "Immunochemical and toxic properties of the lipopolysaccharides from highly and low virulent Pseudomonas aeruginosa strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217813"} {"pmid": "4217799", "title": "The Rhesus factor in occlusive and ectatic arterial disease.", "content": "The Rhesus factor in occlusive and ectatic arterial disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217799"} {"pmid": "4217815", "title": "A clinical trial of reserpine--clopamide--dihydroergocristine in the treatment of hypertension.", "content": "A clinical trial of reserpine--clopamide--dihydroergocristine in the treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217815"} {"pmid": "4217816", "title": "Some factors affecting the detection of long-acting thyroid stimulator protector using the McKenzie bioassay.", "content": "Some factors affecting the detection of long-acting thyroid stimulator protector using the McKenzie bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217816"} {"pmid": "4217817", "title": "Six years experience with pelvic inflammatory disease.", "content": "Six years experience with pelvic inflammatory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217817"} {"pmid": "4217818", "title": "Free fatty acids, diacyl- and triacylglycerols and total phospholipids in vertebrate retina: comparison with brain, choroid and plasma.", "content": "Free fatty acids, diacyl- and triacylglycerols and total phospholipids in vertebrate retina: comparison with brain, choroid and plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217818"} {"pmid": "4217819", "title": "Human placental lactogen levels in amniotic fluid in rhesus isoimmunization.", "content": "Human placental lactogen levels in amniotic fluid in rhesus isoimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217819"} {"pmid": "4217820", "title": "The effect of copper deficiency on the mandibular joint and alveolar bone of pigs.", "content": "The effect of copper deficiency on the mandibular joint and alveolar bone of pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217820"} {"pmid": "4217821", "title": "Longitudinal studies in oral leukoplakias.", "content": "Longitudinal studies in oral leukoplakias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217821"} {"pmid": "4217822", "title": "The calcifying ghost cell odontogenic tumor - or the calcifying odontogenic cyst.", "content": "The calcifying ghost cell odontogenic tumor - or the calcifying odontogenic cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217822"} {"pmid": "4217824", "title": "Lignans from Larrea divaricata.", "content": "Lignans from Larrea divaricata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217824"} {"pmid": "4217823", "title": "Structure of antibodies.", "content": "Structure of antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217823"} {"pmid": "4217827", "title": "Modern radiation therapy of carcinoma of the prostate.", "content": "Modern radiation therapy of carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217827"} {"pmid": "4217831", "title": "The prevalence of long-term illness in a family practice.", "content": "The prevalence of long-term illness in a family practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217831"} {"pmid": "4217832", "title": "Calcium ions and control of the motility of sea urchin spermatozoa.", "content": "Calcium ions and control of the motility of sea urchin spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217832"} {"pmid": "4217833", "title": "The incidence of Brucella ovis infection in South African rams: a serological survey.", "content": "The incidence of Brucella ovis infection in South African rams: a serological survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217833"} {"pmid": "4217834", "title": "Brucellosis in Rhodesian Wildlife.", "content": "Brucellosis in Rhodesian Wildlife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217834"} {"pmid": "4217835", "title": "Anthrax in an African buffalo (Syncerus caffer) in the Kruger National Park.", "content": "Anthrax in an African buffalo (Syncerus caffer) in the Kruger National Park.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217835"} {"pmid": "4217837", "title": "Editorial: Monkeys, models, and midwives.", "content": "Editorial: Monkeys, models, and midwives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217837"} {"pmid": "4217838", "title": "Heteroagglutinins in human sera specific for erythrocytes of nonhuman primates.", "content": "Heteroagglutinins in human sera specific for erythrocytes of nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217838"} {"pmid": "4217836", "title": "Antimicrobial effectiveness ofkanamycin, aminosidin, BB-K8, sisomicin, gentamicin and tobramycin combined with carbenicillin or cephalothin against gram-negative rods.", "content": "Antimicrobial effectiveness ofkanamycin, aminosidin, BB-K8, sisomicin, gentamicin and tobramycin combined with carbenicillin or cephalothin against gram-negative rods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217836"} {"pmid": "4217839", "title": "Recent developments of biomedical research in nonhuman primates. With a short historical review.", "content": "Recent developments of biomedical research in nonhuman primates. With a short historical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217839"} {"pmid": "4217840", "title": "Cholesterol gallstones in Aotus trivirgatus.", "content": "Cholesterol gallstones in Aotus trivirgatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217840"} {"pmid": "4217841", "title": "Paramyosin of Caenorhabditis elegans.", "content": "Paramyosin of Caenorhabditis elegans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217841"} {"pmid": "4217842", "title": "Chromosomes segregration and development in Caulobacter crescentus.", "content": "Chromosomes segregration and development in Caulobacter crescentus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217842"} {"pmid": "4217843", "title": "Effect of glutaraldehyde and urea embedding on intracellular ionic elements. X-ray microanalysis of skeletal muscle and myocardium.", "content": "Effect of glutaraldehyde and urea embedding on intracellular ionic elements. X-ray microanalysis of skeletal muscle and myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217843"} {"pmid": "4217844", "title": "Structural variability of immunoglobulins.", "content": "Structural variability of immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217844"} {"pmid": "4217846", "title": "Single radial diffusion using catalase antibody as screening method of hypocatalasemia.", "content": "Single radial diffusion using catalase antibody as screening method of hypocatalasemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217846"} {"pmid": "4217845", "title": "Ethnic characteristics of the kappa : lambda ratio of immunoglobulins in health and disease of the Japanes and Occidental.", "content": "Ethnic characteristics of the kappa : lambda ratio of immunoglobulins in health and disease of the Japanes and Occidental.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217845"} {"pmid": "4217847", "title": "Antigenic analyses of sequential isolates of Coxsackie A16 virus from 1964 to 1970 in Japan.", "content": "Antigenic analyses of sequential isolates of Coxsackie A16 virus from 1964 to 1970 in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217847"} {"pmid": "4217865", "title": "Effect of CaEDTA administration on urinary hydroxyproline excretion and skin wound healing in the rat.", "content": "Effect of CaEDTA administration on urinary hydroxyproline excretion and skin wound healing in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217865"} {"pmid": "4217866", "title": "Healing of lined and unlined parasitic and nonparasitic flaps.", "content": "Healing of lined and unlined parasitic and nonparasitic flaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217866"} {"pmid": "4217873", "title": "Structural components of measles virus.", "content": "Structural components of measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217873"} {"pmid": "4217874", "title": "Intracellular accumulation of measles virus nucleocapsid and envelope antigens.", "content": "Intracellular accumulation of measles virus nucleocapsid and envelope antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217874"} {"pmid": "4217872", "title": "[Isolation of murein-free spheroplast ghosts from a strain of Escherichia coli K 12].", "content": "[Isolation of murein-free spheroplast ghosts from a strain of Escherichia coli K 12].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217872"} {"pmid": "4217883", "title": "The use of Microstix in the diagnosis of urinary tract infections.", "content": "The use of Microstix in the diagnosis of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217883"} {"pmid": "4217884", "title": "Diuretics, cardiac failure and potassium depletion: a rational approach.", "content": "Diuretics, cardiac failure and potassium depletion: a rational approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217884"} {"pmid": "4217885", "title": "Surgical drapes and their permeability to bacteria.", "content": "Surgical drapes and their permeability to bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217885"} {"pmid": "4217887", "title": "Renaturation of denatured DNA in NaI gradients.", "content": "Renaturation of denatured DNA in NaI gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217887"} {"pmid": "4217889", "title": "Single-drug therapy in ovarian cancer.", "content": "Single-drug therapy in ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217889"} {"pmid": "4217890", "title": "Identification and typing of viruses and detection of antiviral antibodies by counterimmunoelectrophoresis.", "content": "Identification and typing of viruses and detection of antiviral antibodies by counterimmunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217890"} {"pmid": "4217891", "title": "F antigen. I. Purification and polymorphism.", "content": "F antigen. I. Purification and polymorphism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217891"} {"pmid": "4217896", "title": "Laser damage to ocular tissues.", "content": "Laser damage to ocular tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217896"} {"pmid": "4217897", "title": "Ocular examination of laser workers and investigation of accidents.", "content": "Ocular examination of laser workers and investigation of accidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217897"} {"pmid": "4217898", "title": "Laser safety codes.", "content": "Laser safety codes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217898"} {"pmid": "4217899", "title": "Physiological actions of prolactin.", "content": "Physiological actions of prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217899"} {"pmid": "4217900", "title": "Radioimmunoassay of human prolactin.", "content": "Radioimmunoassay of human prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217900"} {"pmid": "4217901", "title": "Prolactin studies in normal subjects.", "content": "Prolactin studies in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217901"} {"pmid": "4217902", "title": "Systemic sarcoidosis with massive hepatic involvement.", "content": "Systemic sarcoidosis with massive hepatic involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217902"} {"pmid": "4217903", "title": "Immunological and clinical findings in workers and consumers exposed to enzymes of Bacillus subtilis.", "content": "Immunological and clinical findings in workers and consumers exposed to enzymes of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217903"} {"pmid": "4217905", "title": "A technique of after-loading: high dose-rates.", "content": "A technique of after-loading: high dose-rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217905"} {"pmid": "4217904", "title": "Clinical findings in workers exposed to the enzymes of Bacillus subtilis.", "content": "Clinical findings in workers exposed to the enzymes of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217904"} {"pmid": "4217907", "title": "Letter: The calculation of ionization chamber collection efficiency for pulsed beams.", "content": "Letter: The calculation of ionization chamber collection efficiency for pulsed beams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217907"} {"pmid": "4217906", "title": "Radiotherapy of testicular tumours.", "content": "Radiotherapy of testicular tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217906"} {"pmid": "4217908", "title": "Immunodeficiency: enigmas and speculations.", "content": "Immunodeficiency: enigmas and speculations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217908"} {"pmid": "4217909", "title": "Surface immunoglobulins on human lymphoid cells.", "content": "Surface immunoglobulins on human lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217909"} {"pmid": "4217910", "title": "Therapeutic uses of transfer factor.", "content": "Therapeutic uses of transfer factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217910"} {"pmid": "4217911", "title": "Toxicity of propellants.", "content": "Toxicity of propellants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217911"} {"pmid": "4217918", "title": "The use of the antiglobulin test in the diagnosis of bovine brucellosis.", "content": "The use of the antiglobulin test in the diagnosis of bovine brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217918"} {"pmid": "4217919", "title": "Parenteral infection of laboratory animals with metacercariae of Fasciola hepatica.", "content": "Parenteral infection of laboratory animals with metacercariae of Fasciola hepatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217919"} {"pmid": "4217920", "title": "Duration of serological response to the indirect fluorescent antibody test of cattle recovered from Theileria parva infection.", "content": "Duration of serological response to the indirect fluorescent antibody test of cattle recovered from Theileria parva infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217920"} {"pmid": "4217922", "title": "Natural resistance to infection in the newborn sheep: competence of local and and systemic defences in normally-sukled and colostrum-deprived lambs.", "content": "Natural resistance to infection in the newborn sheep: competence of local and and systemic defences in normally-sukled and colostrum-deprived lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217922"} {"pmid": "4217921", "title": "The detection of tuberculin-sensitive lymphocytes from bovine blood by uptake of radio-labelled nucleosides.", "content": "The detection of tuberculin-sensitive lymphocytes from bovine blood by uptake of radio-labelled nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217921"} {"pmid": "4217923", "title": "Distribution of Brucella antibody among immunoglobulin classes and a low molecular weight antibody fraction in serum and whey of cattle.", "content": "Distribution of Brucella antibody among immunoglobulin classes and a low molecular weight antibody fraction in serum and whey of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217923"} {"pmid": "4217924", "title": "Changes in the serum immunoglobulin levels of colostrum-fed calves during the first 12 weeks postpartum.", "content": "Changes in the serum immunoglobulin levels of colostrum-fed calves during the first 12 weeks postpartum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217924"} {"pmid": "4217916", "title": "The influence of endocrine and exocrine pancreas on the carbonic anhydrase activity of the rat salivary glands.", "content": "The influence of endocrine and exocrine pancreas on the carbonic anhydrase activity of the rat salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217916"} {"pmid": "4217937", "title": "The effect of stimulation of central end of the vagus on the phrenic activity after strichnine and picroxin.", "content": "The effect of stimulation of central end of the vagus on the phrenic activity after strichnine and picroxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217937"} {"pmid": "4217939", "title": "Morphological examinations of pancreatic tissue in dog with acute pancreatitis.", "content": "Morphological examinations of pancreatic tissue in dog with acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217939"} {"pmid": "4217940", "title": "Differential thermal analysis of oral and palmar epithelium.", "content": "Differential thermal analysis of oral and palmar epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217940"} {"pmid": "4217942", "title": "A mutant of Bacillus subtilis with impaired ability for recombination and reduced activity of the enzyme ATP-dependent deoxyribonuclease.", "content": "A mutant of Bacillus subtilis with impaired ability for recombination and reduced activity of the enzyme ATP-dependent deoxyribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217942"} {"pmid": "4217941", "title": "Deposits of immunoglobulins and complement in oral lupus erythematosus.", "content": "Deposits of immunoglobulins and complement in oral lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217941"} {"pmid": "4217943", "title": "Distribution of defective chromosomes in human cells after treatment with chemical mutagens in vitro and in vivo.", "content": "Distribution of defective chromosomes in human cells after treatment with chemical mutagens in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217943"} {"pmid": "4217946", "title": "Calibration and measurement of potassium-40 with a whole-body counter.", "content": "Calibration and measurement of potassium-40 with a whole-body counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217946"} {"pmid": "4217948", "title": "Transport of materials in the suctorian tentacle.", "content": "Transport of materials in the suctorian tentacle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217948"} {"pmid": "4217949", "title": "Pathways of nucleocytoplasmic translocation of ribonucleoproteins.", "content": "Pathways of nucleocytoplasmic translocation of ribonucleoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217949"} {"pmid": "4217954", "title": "Electronic platelet counting after isopycnic differential centrifugation a simple rapid and accurate method.", "content": "Electronic platelet counting after isopycnic differential centrifugation a simple rapid and accurate method. A semi-automatized platelet counting procedure with the use of a Coulter Counter is described. Its originality consists in providing an electronic method of counting of the platelets after a differential centrifugation of the blood sample previously diluted with a hypertonic NaCl solution (density 1.053) which is isopycnic to platelet density. This procedure allows elimination of red and white cells without loss of platelets in the supernatant. The final platelet number can be calculated without further corrections. The method is quick and does not require specially skilled technicians. A single technician can perform 40 counts in one hour. The reproductibility of the method is excellent and the coefficient of variation 2,4%. The accuracy and feasibility of the method is also sustained by two years' experience in an haematological routine laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217954"} {"pmid": "4217955", "title": "Fibrinogen Valencia. A new case of congenital dysfibrinogenemia.", "content": "Fibrinogen Valencia. A new case of congenital dysfibrinogenemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217955"} {"pmid": "4217960", "title": "Separation and characterization of immunoglobulin classes of anti-salmon sperm deoxyribonucleic acid antibodies in rabbits.", "content": "Separation and characterization of immunoglobulin classes of anti-salmon sperm deoxyribonucleic acid antibodies in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217960"} {"pmid": "4217964", "title": "Regeneration and functional recovery of canine intestinal mucosa following injury caused by formalin.", "content": "Regeneration and functional recovery of canine intestinal mucosa following injury caused by formalin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217964"} {"pmid": "4217965", "title": "The ultrastructural effects of aflatoxin B1 in the rat pancreas.", "content": "The ultrastructural effects of aflatoxin B1 in the rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217965"} {"pmid": "4217966", "title": "Aurosomes in rabbit articular cartilage.", "content": "Aurosomes in rabbit articular cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217966"} {"pmid": "4217969", "title": "A scanning electron microscope study of the glomerulus of normal and nephritic rabbits.", "content": "A scanning electron microscope study of the glomerulus of normal and nephritic rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217969"} {"pmid": "4217970", "title": "Immunofluorescent studies on the occurrence of cathepsin B1 at tumor cell surfaces.", "content": "Immunofluorescent studies on the occurrence of cathepsin B1 at tumor cell surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217970"} {"pmid": "4217971", "title": "From studies on the parasitic Ciliata invading plant-feeding species of fish in ponds.", "content": "From studies on the parasitic Ciliata invading plant-feeding species of fish in ponds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217971"} {"pmid": "4217972", "title": "Nutrition after injury.", "content": "Nutrition after injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217972"} {"pmid": "4217976", "title": "The economics of human parasitic infections.", "content": "The economics of human parasitic infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217976"} {"pmid": "4217974", "title": "Advances in the biology of sporozoa.", "content": "Advances in the biology of sporozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217974"} {"pmid": "4217975", "title": "Advances in the immunodiagnosis of parasitic infections.", "content": "Advances in the immunodiagnosis of parasitic infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4217975"} {"pmid": "4218000", "title": "Australia antigen (Au(1), HAA, HABg) in expatriates living in Ibadan, Nigeria.", "content": "Australia antigen (Au(1), HAA, HABg) in expatriates living in Ibadan, Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218000"} {"pmid": "4218050", "title": "Studies of the actions of thiols, lithium ions and insulin on carbohydrate metabolism of the isolated rat diaphragm.", "content": "Studies of the actions of thiols, lithium ions and insulin on carbohydrate metabolism of the isolated rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218050"} {"pmid": "4218051", "title": "Proceedings: Effects of centrophenoxine and palmitoylethanolamide in rats with early protein and calorie malnutrition. I. Neurological tests.", "content": "Proceedings: Effects of centrophenoxine and palmitoylethanolamide in rats with early protein and calorie malnutrition. I. Neurological tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218051"} {"pmid": "4218052", "title": "Proceedings: The effects of centrophenoxine and palmitoylethanolamide in rats with early protein and calorie malnutrition. II. Somatic and biochemical parameters.", "content": "Proceedings: The effects of centrophenoxine and palmitoylethanolamide in rats with early protein and calorie malnutrition. II. Somatic and biochemical parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218052"} {"pmid": "4218053", "title": "Transfer of TRH through the placenta and metabolism in the fetus of the guinea-pig.", "content": "Transfer of TRH through the placenta and metabolism in the fetus of the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218053"} {"pmid": "4218054", "title": "A serum factor influencing the physiological activity of thyrotropin-releasing hormone (TRH) I. Studies with human serum.", "content": "A serum factor influencing the physiological activity of thyrotropin-releasing hormone (TRH) I. Studies with human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218054"} {"pmid": "4218055", "title": "A serum factor influencing the physiological activity of thyrotropin-releasing hormone (TRH). II. Studies with rat serum in vivo and in vitro.", "content": "A serum factor influencing the physiological activity of thyrotropin-releasing hormone (TRH). II. Studies with rat serum in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218055"} {"pmid": "4218056", "title": "Autoradiographic - histochemical demonstration of tyrosinase activity in melanin-forming tissues of mammals.", "content": "Autoradiographic - histochemical demonstration of tyrosinase activity in melanin-forming tissues of mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218056"} {"pmid": "4218058", "title": "Vascular supply of the rat medial basal hypothalamus and development of vascular connections between this region and the rest of the brain following deafferentation of the former area.", "content": "Vascular supply of the rat medial basal hypothalamus and development of vascular connections between this region and the rest of the brain following deafferentation of the former area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218058"} {"pmid": "4218059", "title": "\"Monoclonal\" IgM-gammopathy with two different light-chain types of protein (Bence-Jones I and II).", "content": "\"Monoclonal\" IgM-gammopathy with two different light-chain types of protein (Bence-Jones I and II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218059"} {"pmid": "4218060", "title": "Experimental chemotherapy of Schistosomiasis mansoni.", "content": "Experimental chemotherapy of Schistosomiasis mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218060"} {"pmid": "4218062", "title": "Corynebacterium pyrogenes; a biochemical and serological study.", "content": "Corynebacterium pyrogenes; a biochemical and serological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218062"} {"pmid": "4218063", "title": "Estrone and progesterone plasma levels of normal cows and cows with parturient paresis.", "content": "Estrone and progesterone plasma levels of normal cows and cows with parturient paresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218063"} {"pmid": "4218065", "title": "The occurrence of antibodies against staphylococcal deoxyribonucleases in blood sera from different species.", "content": "The occurrence of antibodies against staphylococcal deoxyribonucleases in blood sera from different species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218065"} {"pmid": "4218064", "title": "Serum levels of the immunoglobulins IgG and IgG(T) in horses.", "content": "Serum levels of the immunoglobulins IgG and IgG(T) in horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218064"} {"pmid": "4218049", "title": "Inhibition of the diuretic action of glibenclamide by clofibrate, carbamazepine and 1-deamino-8-d-arginine-vasopressin (DDAVP) in patients with pituitary diabetes insipidus.", "content": "Inhibition of the diuretic action of glibenclamide by clofibrate, carbamazepine and 1-deamino-8-d-arginine-vasopressin (DDAVP) in patients with pituitary diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218049"} {"pmid": "4218072", "title": "Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study.", "content": "Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study. Pseudomonas aeruginosa was exposed to 0.1, 1.0, 10, 100, and 1,000 times the minimal inhibitory concentration of ticarcillin in vitro and subsequently examined with the scanning electron microscope. The morphological alterations observed were filamentation, mid-cell defects, and spheroplast formation, and these alterations were dependent upon the drug concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218072"} {"pmid": "4218068", "title": "Evaluation of antigen-coated red cells for detection of serum hepatitis antigen and antibody.", "content": "Evaluation of antigen-coated red cells for detection of serum hepatitis antigen and antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218068"} {"pmid": "4218087", "title": "Formation of protoplasts in Azotobacter vinelandii.", "content": "Formation of protoplasts in Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218087"} {"pmid": "4218089", "title": "Use of a triple layer enzyme method as an alternative to immunofluorescence for the detection of tissue antigens.", "content": "Use of a triple layer enzyme method as an alternative to immunofluorescence for the detection of tissue antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218089"} {"pmid": "4218088", "title": "Intoxication, detoxication and copper-storage of central nervous tissue at different external Cu(II)-concentrations.", "content": "Intoxication, detoxication and copper-storage of central nervous tissue at different external Cu(II)-concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218088"} {"pmid": "4218091", "title": "Rapid titration of dengue virus type 4 infectivity by counting fluorescent foci.", "content": "Rapid titration of dengue virus type 4 infectivity by counting fluorescent foci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218091"} {"pmid": "4218092", "title": "Purification of human placental alkaline phosphatase. Salt effects in affinity chromatography.", "content": "Purification of human placental alkaline phosphatase. Salt effects in affinity chromatography. Human placental alkaline phosphatase was chromatographed on Sepharose derivatives of d- and l-phenylalanine, l-leucine, glycine, aniline and p-aminobenzoic acid in high concentrations of (NH(4))(2)SO(4). Retention on these columns was greatest at the highest concentrations of (NH(4))(2)SO(4). By using decreasing concentrations and changing the types of salts, elution was effected from each of the columns. The (NH(4))(2)SO(4)-mediated retention appeared to be related to the hydrophobic character of the substituted Sepharose, rather than to any specific binding site of the enzyme. It is suggested that this provides a way of controlling hydrophobic affinity chromatography. By use of chromatography on l-phenylalanine-Sepharose and of DEAE-Sephadex chromatography in the presence of Triton X-100 detergent, a preparation of highly purified (1000-fold) human placental alkaline phosphatase was obtained in 22% yield.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218092"} {"pmid": "4218093", "title": "An electron-capture gas-liquid-chromatographic method for the determination of prostaglandin F2alpha in biological fluids.", "content": "An electron-capture gas-liquid-chromatographic method for the determination of prostaglandin F2alpha in biological fluids. A sensitive electron-capture gas-liquid-chromatographic method for the determination of sub-nanogram quantities of prostaglandin F(2alpha) was developed. The method is based on the sub-microgram scale conversion of the prostaglandin into the electron-capturing pentafluorobenzyl ester, and analysis of the latter as the tris-trimethylsilyl ether. The lower limit of detection was 12.5pg of the ester injected ;on-column' as the silylated product. The method was successfully applied to the determination of prostaglandin F(2alpha) in monkey plasma. The specificity of the analytical procedure was increased by incorporating a thin-layer chromatographic fractionation before gas-liquid chromatography. The utility of the analytical methodology developed was demonstrated by its application to the determination of plasma concentrations of intact prostaglandin F(2alpha) in a Rhesus monkey, after subcutaneous administration of a single dose of prostaglandin F(2alpha). The electron-capture gas-liquid-chromatographic assay is compared with the radioimmunoassay and the gas-liquid-chromatographic-mass-spectrometry assay for the determination of prostaglandin F(2alpha).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218093"} {"pmid": "4218094", "title": "Thermal inactivation studies of normal and variant human erythrocyte carbonic anhydrases by using a sulphonamide-binding assay.", "content": "Thermal inactivation studies of normal and variant human erythrocyte carbonic anhydrases by using a sulphonamide-binding assay. Heat-inactivation studies were carried out on the two primary erythrocyte carbonic anhydrase isoenzymes, CA I and CA II, and the secondary isoenzyme of CA I, CA I (+1). In addition, two genetic variants of human isoenzyme CA I, CA Id Michigan (100 Thr-->Lys) and CA If London (102 Glu-->Lys), and one variant of isoenzyme CA II, CA IIh (251 Asn-->Asp), were similarly analysed. The first-order rate constants and Arrhenius plots for these six enzyme forms showed that (1) isoenzyme CA II is more heat-stable than CA I, (2) isoenzyme CA I (+1) is less heat-stable than CA I, (3) the variants CA IIh and CA If London are less heat-stable than the normal enzymes, and (4) isoenzyme CA Id Michigan is more heat-stable than normal CA I. From the values of the slopes of the Arrhenius plots, the energy of activation (E(a)) for each isoenzyme and isoenzyme variant was determined, and the following thermodynamic activation parameters were calculated at 55 degrees C: the free energy of activation (DeltaG(double dagger)), the activation enthalpy (DeltaH(double dagger)) and the activation entropy (DeltaS(double dagger)). The DeltaG(double dagger) for the enzymes shows a relative constancy with compensating variation in DeltaH(double dagger) and DeltaS(double dagger). When the values for DeltaH(double dagger) are plotted against DeltaS(double dagger), an increase in DeltaH(double dagger) involves a concomitant increase in DeltaS(double dagger).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218094"} {"pmid": "4218095", "title": "Chemical and immunochemical characteristics of tropomyosins from striated and smooth muscle.", "content": "Chemical and immunochemical characteristics of tropomyosins from striated and smooth muscle. 1. On electrophoresis in dissociating conditions the tropomyosins isolated from skeletal muscles of mammalian, avian and amphibian species migrated as two components. These were comparable with the alpha and beta subunits of tropomyosin present in rabbit skeletal muscle. 2. The alpha and beta components of all skeletal-muscle tropomyosins contained 1 and 2 residues of cysteine per 34000g respectively. 3. The ratio of the amounts of alpha and beta subunit present in skeletal muscle tropomyosins was characteristic for the muscle type. Muscle consisting of slow red fibres contained a greater proportion of beta-tropomyosin than muscles consisting predominantly of white fast fibres. 4. Mammalian and avian cardiac muscle tropomyosins consisted of alpha-tropomyosin only. 5. Mammalian and avian smooth-muscle tropomyosins differed both chemically and immunologically from striated-muscle tropomyosins. 6. Antibody raised against rabbit skeletal alpha-tropomyosin was species non-specific, reacting with all other striated muscle alpha-tropomyosin subunits tested. 7. Antibody raised against rabbit skeletal beta-tropomyosin subunit was species-specific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218095"} {"pmid": "4218096", "title": "Comparison of the biliproteins from two strains of the thermophilic cyanophyte Synechococcus lividus.", "content": "Comparison of the biliproteins from two strains of the thermophilic cyanophyte Synechococcus lividus. C-Phycocyanins from two thermophilic strains of Synechococcus lividus that grow within different temperature ranges have been shown to be unalike. The aggregation ability of these two C-phycocyanins in sedimentation-velocity experiments varied dramatically. Surprisingly, the aggregation properties of mesophilic C-phycocyanins were found to lie between those of the two thermophilic proteins. Under identical conditions at pH7.0, one thermophilic protein (Sy I) was composed of 17S and larger aggregates, whereas the other (Sy III) was an almost homogeneous 6S aggregate. Mesophilic C-phycocyanins have a mixture of 6S, 11S and less stable 17S aggregates under these conditions. Amino acid analysis, absorption spectra, immunochemistry and fluorescence polarization all indicated differences in the composition and properties of the thermophilic proteins, which suggest that they have different modes of adaptation to very high temperatures. Allophycocyanins from the two strains of S. lividus were also purified and studied, but unlike the C-phycocyanins no major differences were found between them. Allophycocyanin was homogeneous at pH6.0, with a sedimentation coefficient of 5.54S and mol.wt. 1.03x10(5), as determined by sedimentation-equilibrium measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218096"} {"pmid": "4218097", "title": "A more detailed study of bile salt evolution, including techniques for small-scale identification and their application to amphibian biles.", "content": "A more detailed study of bile salt evolution, including techniques for small-scale identification and their application to amphibian biles. 1. Methods have been developed for the isolation and identification of small amounts of bile salts and of bile acids and alcohols obtained by solvolysis. These methods involve preparative and analytical t.l.c., purification on columns of protonated Al(2)O(3) and Sephadex LH-20 and also g.l.c.-mass spectroscopy of solvolysis products. 2. Application to 29 species of frogs and toads has confirmed the constancy of bile salt patterns in a single species, including colour phases in two instances, and has revealed great variations between different species in some genera (e.g. Rana, Ptychadena) and little difference between widely distributed species in others (e.g. Bufo). 3. Taxonomic deductions should be made with caution and with regard to the physiological significance of the biochemical character considered. The molecular differences found might be interpreted as indicating variations in the rate of evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218097"} {"pmid": "4218098", "title": "Pyruvate and nitrogenase activity in cell-free extracts of the blue-green alga Anabaena cylindrica.", "content": "Pyruvate and nitrogenase activity in cell-free extracts of the blue-green alga Anabaena cylindrica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218098"} {"pmid": "4218099", "title": "The amino acid sequence of the C- terminal cyanogen bromide peptide of human J chain.", "content": "The amino acid sequence of the C- terminal cyanogen bromide peptide of human J chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218099"} {"pmid": "4218100", "title": "Morquio's syndrome: deficiency of a chondroitin sulfate N-acetylhexosamine sulfate sulfatase.", "content": "Morquio's syndrome: deficiency of a chondroitin sulfate N-acetylhexosamine sulfate sulfatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218100"} {"pmid": "4218102", "title": "Identification of several unique low molecular weight basic proteins in dormant spores of Bacillus megaterium and their degradation during spore germination.", "content": "Identification of several unique low molecular weight basic proteins in dormant spores of Bacillus megaterium and their degradation during spore germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218102"} {"pmid": "4218101", "title": "Amino acid sequence of Streptomyces griseus protease B, A MAJOR COMPONENT OF Pronase.", "content": "Amino acid sequence of Streptomyces griseus protease B, A MAJOR COMPONENT OF Pronase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218101"} {"pmid": "4218103", "title": "The occurrence of a transmethylation reaction not involving S-adenosylmethionine in the formation of ribothymidine in Bacillus subtilis transfer-RNA.", "content": "The occurrence of a transmethylation reaction not involving S-adenosylmethionine in the formation of ribothymidine in Bacillus subtilis transfer-RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218103"} {"pmid": "4218104", "title": "Decarboxylation of long chain fatty acids to alkanes by cell free preparations of pea leaves (Pisum sativum).", "content": "Decarboxylation of long chain fatty acids to alkanes by cell free preparations of pea leaves (Pisum sativum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218104"} {"pmid": "4218105", "title": "Proton Magnetic resonance observations of hydrogen exchange rates and secondary structure in algal ferredoxin.", "content": "Proton Magnetic resonance observations of hydrogen exchange rates and secondary structure in algal ferredoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218105"} {"pmid": "4218106", "title": "Crystallisation of purified thyroxine-binding alpha globulin.", "content": "Crystallisation of purified thyroxine-binding alpha globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218106"} {"pmid": "4218107", "title": "Deficiency of chondroitin sulfate N-acetylgalactosamine 4-sulfate sulfatase in Maroteaux-Lamy syndrome.", "content": "Deficiency of chondroitin sulfate N-acetylgalactosamine 4-sulfate sulfatase in Maroteaux-Lamy syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218107"} {"pmid": "4218108", "title": "Effect of silybin on the hepatic microsomal drug-metabolising enzyme system in the rat.", "content": "Effect of silybin on the hepatic microsomal drug-metabolising enzyme system in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218108"} {"pmid": "4218113", "title": "The effect of sex difference on iron exchange in the rat.", "content": "The effect of sex difference on iron exchange in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218113"} {"pmid": "4218114", "title": "Ocular histoplasmosis syndrome in the United Kingdom.", "content": "Ocular histoplasmosis syndrome in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218114"} {"pmid": "4218115", "title": "Studies on the radiation-induced dissociation and reassociation of polysomes in Tetrahymena pyriformis.", "content": "Studies on the radiation-induced dissociation and reassociation of polysomes in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218115"} {"pmid": "4218116", "title": "A comparative examination of amphibian sperm proteolytic activity.", "content": "A comparative examination of amphibian sperm proteolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218116"} {"pmid": "4218117", "title": "Machine for the automatic washing of red blood cells and its use in the assay of anti-D antibody.", "content": "Machine for the automatic washing of red blood cells and its use in the assay of anti-D antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218117"} {"pmid": "4218118", "title": "Immunosuppression and experimental tuberculosis. II. The effects of immunosuppressive agents and antilymphocyte serum on the organ dissemination of mycobacteria and on the development of specific delayed hypersensitivity.", "content": "Immunosuppression and experimental tuberculosis. II. The effects of immunosuppressive agents and antilymphocyte serum on the organ dissemination of mycobacteria and on the development of specific delayed hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218118"} {"pmid": "4218120", "title": "Interactions of PCBs, DDT and DDE in a marine diatom.", "content": "Interactions of PCBs, DDT and DDE in a marine diatom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218120"} {"pmid": "4218119", "title": "Determination of pentachlorophenol and chlorobiphenylols in biological samples.", "content": "Determination of pentachlorophenol and chlorobiphenylols in biological samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218119"} {"pmid": "4218121", "title": "Co-carcinogenic effect of DDT and PCB feeding on methylcholanthrene-induced chemical carcinogenesis.", "content": "Co-carcinogenic effect of DDT and PCB feeding on methylcholanthrene-induced chemical carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218121"} {"pmid": "4218122", "title": "PCB residues in plankton and sediment in the southwestern coast of Finland.", "content": "PCB residues in plankton and sediment in the southwestern coast of Finland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218122"} {"pmid": "4218123", "title": "Clinical and EEG studies of prisoners charged with murder.", "content": "Clinical and EEG studies of prisoners charged with murder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218123"} {"pmid": "4218125", "title": "The potential of coenzyme Q 10 (NSC-140865) in cancer treatment.", "content": "The potential of coenzyme Q 10 (NSC-140865) in cancer treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218125"} {"pmid": "4218126", "title": "Antigen binding to lymphoid cells from unimmunized mice: high frequency of beta-galactosidase binding cells at optimal conditions.", "content": "Antigen binding to lymphoid cells from unimmunized mice: high frequency of beta-galactosidase binding cells at optimal conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218126"} {"pmid": "4218127", "title": "Kinetics of B cell memory development during a thymus \"independent\" immune response.", "content": "Kinetics of B cell memory development during a thymus \"independent\" immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218127"} {"pmid": "4218128", "title": "Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages.", "content": "Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218128"} {"pmid": "4218129", "title": "Observations on migration inhibition of sensitized peritoneal exudate cells as a function of time.", "content": "Observations on migration inhibition of sensitized peritoneal exudate cells as a function of time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218129"} {"pmid": "4218131", "title": "Cooperation of three lymphoid cells in allograft rejection.", "content": "Cooperation of three lymphoid cells in allograft rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218131"} {"pmid": "4218130", "title": "Immunoglobulin on activated T cells detected by indirect immunofluorescence.", "content": "Immunoglobulin on activated T cells detected by indirect immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218130"} {"pmid": "4218132", "title": "Characterization of contrasensitizing antibodies.", "content": "Characterization of contrasensitizing antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218132"} {"pmid": "4218133", "title": "In vitro suppression ofimmunoglobulin allotype synthesis by Fab and F(ab')2 fragments of anti-allotype antibody.", "content": "In vitro suppression ofimmunoglobulin allotype synthesis by Fab and F(ab')2 fragments of anti-allotype antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218133"} {"pmid": "4218137", "title": "Immunology of Chagas' disease.", "content": "Immunology of Chagas' disease. After reviewing present knowledge of the morphology, multiplication, and transmission of Trypanosoma cruzi, this Memorandum discusses the animal models that may be of value in understanding the immune mechanisms operating in Chagas' disease. The role of both circulating antibody and cell-mediated immunity in protection against the parasite is discussed, together with the possibility that immunopathological mechanisms may be responsible for some of the lesions found in patients with Chagas' disease. The immunodiagnostic methods at present available are also reviewed, and the possibility of producing a vaccine for human use is considered in the light of recent findings in experimental animals. A series of recommendations for further research is included.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218137"} {"pmid": "4218138", "title": "Antigenic variation in current influenza A viruses: evidence for a high frequency of antigenic 'drift' for the Hong Kong virus.", "content": "Antigenic variation in current influenza A viruses: evidence for a high frequency of antigenic 'drift' for the Hong Kong virus. A new antigenic variant of the Hong Kong (H3N2) subtype of influenzavirus type A is described. The variant, A/Port Chalmers/1/73 (H3N2), was first isolated in Australasia in the autumn of 1973 and subsequently became the predominant influenza A variant in most areas of the world, replacing the previously prevalent strain A/England/42/72 (H3N2). The 1973 variant shows antigenic differences from former Hong Kong variants in both haemagglutinin and neuraminidase antigens. The application of immuno-double-diffusion tests and single-radial-diffusion tests in the antigenic analysis of new variants of the influenzavirus is also described. It is emphasized that since new variants of the Hong Kong virus have appeared in the successive years 1971, 1972, and 1973, the annual frequency of antigenic \"drift\" for the Hong Kong virus is higher than was recorded for the \"Asian\" influenzavirus (H2N2) in the first 5 years of the latter's prevalence from 1957 to 1962, during which period little antigenic variation occurred.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218138"} {"pmid": "4218139", "title": "A simple technique for culturing tubercle bacilli.", "content": "A simple technique for culturing tubercle bacilli. Microscopy, traditionally used in peripheral health centres to diagnose tuberculosis, could be supplemented by sputum culture if sputum specimens were inoculated on suitable media and sent to intermediate or central laboratories to be incubated and read. To facilitate this procedure, the authors propose a simplified swab culture method and a modification of Ogawa's egg medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218139"} {"pmid": "4218142", "title": "Physiology and treatment of hypoxia.", "content": "Physiology and treatment of hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218142"} {"pmid": "4218143", "title": "Immunochemical investigation of the antigens of drug-resistant staphylococcal strains.", "content": "Immunochemical investigation of the antigens of drug-resistant staphylococcal strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218143"} {"pmid": "4218144", "title": "Some aspects of methicillin-resistance of Staphylococcus aureus.", "content": "Some aspects of methicillin-resistance of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218144"} {"pmid": "4218145", "title": "In vitro effects of staphylococcal alpha and delta toxins on liver mitochondria.", "content": "In vitro effects of staphylococcal alpha and delta toxins on liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218145"} {"pmid": "4218146", "title": "Staphylococcal hyaluronate lyase.", "content": "Staphylococcal hyaluronate lyase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218146"} {"pmid": "4218147", "title": "Bacteriological control of dissemination of Staphylococcus aureus at an intensive care unit.", "content": "Bacteriological control of dissemination of Staphylococcus aureus at an intensive care unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218147"} {"pmid": "4218148", "title": "Epidemiology of enterotoxic strains of Staphylococcus aureus.", "content": "Epidemiology of enterotoxic strains of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218148"} {"pmid": "4218140", "title": "\"Steady-state\" properties of the baroreceptor-heart rate reflex in essential hypertension in man.", "content": "\"Steady-state\" properties of the baroreceptor-heart rate reflex in essential hypertension in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218140"} {"pmid": "4218149", "title": "Serological types of enterotoxins produced by strains of Staphylococcus aureus isolated from feces.", "content": "Serological types of enterotoxins produced by strains of Staphylococcus aureus isolated from feces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218149"} {"pmid": "4218134", "title": "Total parenteral nutrition. Experience with 180 patients.", "content": "Total parenteral nutrition. Experience with 180 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218134"} {"pmid": "4218141", "title": "Coronary haemodynamic effects of nifedipine (Bay a 1040) and glyceryl trinitrate in unanaesthetized dogs.", "content": "Coronary haemodynamic effects of nifedipine (Bay a 1040) and glyceryl trinitrate in unanaesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218141"} {"pmid": "4218150", "title": "Structure and immunology of protein A.", "content": "Structure and immunology of protein A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218150"} {"pmid": "4218152", "title": "Effect of individual ingredients of fortified skim milk as suspending media on survival of freeze-dried cells of Streptococcus lactis.", "content": "Effect of individual ingredients of fortified skim milk as suspending media on survival of freeze-dried cells of Streptococcus lactis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218152"} {"pmid": "4218153", "title": "Comparative trial of tinidazole and metronidazole in intestinal amebiasis.", "content": "Comparative trial of tinidazole and metronidazole in intestinal amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218153"} {"pmid": "4218151", "title": "Effect of carbohydrates and related compounds on the long-term preservation of freeze-dried bacteria.", "content": "Effect of carbohydrates and related compounds on the long-term preservation of freeze-dried bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218151"} {"pmid": "4218154", "title": "A double-blind comparison of phenylbutazone and aspirin in osteoarthritis.", "content": "A double-blind comparison of phenylbutazone and aspirin in osteoarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218154"} {"pmid": "4218155", "title": "Migraleve in the prophylaxis of migraine.", "content": "Migraleve in the prophylaxis of migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218155"} {"pmid": "4218157", "title": "Sensitivity of Pseudomonas aeruginosa to carbenicillin: an evaluation of susceptibility testing after four years of clinical usage.", "content": "Sensitivity of Pseudomonas aeruginosa to carbenicillin: an evaluation of susceptibility testing after four years of clinical usage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218157"} {"pmid": "4218156", "title": "Comparison of migraleve and buclizine in prophylaxis of migraine.", "content": "Comparison of migraleve and buclizine in prophylaxis of migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218156"} {"pmid": "4218158", "title": "Studies on immunodiagnosis of angiostrongyliasis. 5. Double immunodiffusion and counterelectrophoresis for detection of antibody in infected rat and human sera.", "content": "Studies on immunodiagnosis of angiostrongyliasis. 5. Double immunodiffusion and counterelectrophoresis for detection of antibody in infected rat and human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218158"} {"pmid": "4218159", "title": "Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis.", "content": "Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218159"} {"pmid": "4218161", "title": "Thyrotrophin-releasing hormone in diagnosis.", "content": "Thyrotrophin-releasing hormone in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218161"} {"pmid": "4218160", "title": "The genes for ribosomal RNA in diploid and polytene chromosomes of Drosophila melanogaster.", "content": "The genes for ribosomal RNA in diploid and polytene chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218160"} {"pmid": "4218164", "title": "The dysmorphogenic potential of phenytoin: experimental observations.", "content": "The dysmorphogenic potential of phenytoin: experimental observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218164"} {"pmid": "4218166", "title": "Metabolic aspects of methylcyclopentadienyl manganese tricarbonyl in rats.", "content": "Metabolic aspects of methylcyclopentadienyl manganese tricarbonyl in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218166"} {"pmid": "4218167", "title": "Biological fate of -103Pd in rats following different routes of exposure.", "content": "Biological fate of -103Pd in rats following different routes of exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218167"} {"pmid": "4218168", "title": "Some effects of DDT and PCB on the hormonal system in the male mouse.", "content": "Some effects of DDT and PCB on the hormonal system in the male mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218168"} {"pmid": "4218169", "title": "Immunological studies on glutamate dehydrogenase from the cytoplasmatic fraction of rat liver.", "content": "Immunological studies on glutamate dehydrogenase from the cytoplasmatic fraction of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218169"} {"pmid": "4218170", "title": "Immunoglobulin synthesis and glucose-6-phosphate dehydrogenase as cell markers in human lymphoblastoid cell lines.", "content": "Immunoglobulin synthesis and glucose-6-phosphate dehydrogenase as cell markers in human lymphoblastoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218170"} {"pmid": "4218171", "title": "Ghost monolayers in the study of the modulation of transcription in cultures of CV1 fibroblasts.", "content": "Ghost monolayers in the study of the modulation of transcription in cultures of CV1 fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218171"} {"pmid": "4218173", "title": "Partition coefficient of membrane particles in the fusion rosette.", "content": "Partition coefficient of membrane particles in the fusion rosette.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218173"} {"pmid": "4218172", "title": "Ultrastructural detection of single-stranded DNA in rat liver nucleus by the electronmicroscopic immuno-peroxidase method.", "content": "Ultrastructural detection of single-stranded DNA in rat liver nucleus by the electronmicroscopic immuno-peroxidase method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218172"} {"pmid": "4218174", "title": "Stable nuclear RNA returns to post-division nuclei following release to the cytoplasm during mitosis.", "content": "Stable nuclear RNA returns to post-division nuclei following release to the cytoplasm during mitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218174"} {"pmid": "4218175", "title": "Induction of fertilization membrane by ionophore A23187 in sea urchin egg Paracentrotus lividus.", "content": "Induction of fertilization membrane by ionophore A23187 in sea urchin egg Paracentrotus lividus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218175"} {"pmid": "4218165", "title": "Neuropathy in mucopolysaccharidosis type 3.", "content": "Neuropathy in mucopolysaccharidosis type 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218165"} {"pmid": "4218176", "title": "Circadian rhythm in size and 3H-uridine incorporation of single puffs of Drosophila salivary glands in vitro.", "content": "Circadian rhythm in size and 3H-uridine incorporation of single puffs of Drosophila salivary glands in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218176"} {"pmid": "4218177", "title": "Mitogenic stimulation of human leukemic plasma cells.", "content": "Mitogenic stimulation of human leukemic plasma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218177"} {"pmid": "4218179", "title": "The Bacillus Subtilis genome: replication-order and map-position discrepancies--evidence for a second origin.", "content": "The Bacillus Subtilis genome: replication-order and map-position discrepancies--evidence for a second origin. Replication order to map position discrepancies have been documented in B. subtilis. The discrepancies were found to occur whenever the genome of B. subtilis was replicated under a variety of physiological conditions and in both 168 and W23 strains. The earliest replicating marker involved in these discrepancies was thr versus purB and aroA versus recA. A detailed linkage analysis of the ura to argA region was consistent with its being a continuous linkage group. This led to the conclusion that an origin for new starts at replication exists between recA and aroA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218179"} {"pmid": "4218180", "title": "The ribosomes of Drosophila. II. Studies on intraspecific variation.", "content": "The ribosomes of Drosophila. II. Studies on intraspecific variation. Electrophoretic comparisons of 40S and 55S ribosomal subunit proteins from 18 strains of Drosophila melanogaster revealed the virtual absence of allelic variation. More detailed two-dimensional studies on the large subunit proteins in 6 of the strains demonstrated additional complexity but still no interstrain variation. The significance of these results is discussed with respect to present estimates of genic heterozygosity in natural populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218180"} {"pmid": "4218181", "title": "Concurrent multiple paternity in natural and laboratory populations of Drosophila melanogaster.", "content": "Concurrent multiple paternity in natural and laboratory populations of Drosophila melanogaster. Electrophoretic analysis of two or three linked enzyme loci in progenies of homozygous females from cage and natural populations demonstrates frequent concurrent multiple paternity in both cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218181"} {"pmid": "4218182", "title": "The genetic variance for viability and its components in a local population of Drosophila melanogaster.", "content": "The genetic variance for viability and its components in a local population of Drosophila melanogaster. Two hundred and ninety second chromosomes extracted from a natural population of Drosophila melanogaster were analyzed to estimate the genetic variance of viability and its components by means of a partial diallel cross (Design II of Comstock and Robinson 1952). The additive and dominance variances are estimated to be 0.009 and 0.0012. Using the dominance variance and the inbreeding depression, the effective number of overdominant loci contributing to the variance in viability is estimated to be very small, a dozen or less. Either the actual number of loci is small, or the distribution of viabilities is strongly skewed with a large majority of very weakly selected loci. The additive variance in viability appears to be too large to be accounted for by recurrent harmful mutants or by overdominant loci at equilibrium with various genetic parameters estimated independently. The excess might be due to frequency-dependent selection, to negative correlations between viability and fertility, or possibly to the presence of a mutator. The selection for viability and fertility, or possibly to the presence of a mutator. The selection for viability at the average polymorphic locus must be very slight, of the order of 10(-3) or less.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218182"} {"pmid": "4218183", "title": "Variation of spontaneous occurrence rates of chromosomal aberrations in the second chromosomes of Drosophila melanogaster.", "content": "Variation of spontaneous occurrence rates of chromosomal aberrations in the second chromosomes of Drosophila melanogaster. After accumulating mutations by the aid of marked inversions, spontaneous occurrence rates of chromosome aberrations were estimated for 1148 chromosome lines that originated from five stem line second chromosomes of Drosophila melanogaster. In chromosome lines originating from three stem chromosomes (CH, PQ, and RT), mutations were accumulated for 7550, 7252, and 7256 chromosome generations, respectively, but no structural change was detected. For the chromosome lines that originated from the other two stem chromosomes, the situation was different: Twenty aberrations (19 paracentric inversions and 1 translocation between the second and the third chromosomes) during 45990 chromosome generations took place in the 500 chromosome lines derived from stem line chromosome (AW), and 92 aberrations (83 paracentric inversions, 6 pericentric inversions, 2 translocations between the second and the third chromosomes and 1 transposition) arose during 45006 chromosome generations in the 500 chromosome lines derived from stem line chromosome (JH). For the AW group the occurrence rate becomes 0.00043 per chromosome per generation for all aberrations and 0.00041 for inversions. For the JH group the corresponding rates are 0.00204 and 0.00198, respectively.-A non-random distribution of the breakpoint on the salivary gland chromosome was observed and the breakpoints were concentrated in the regions 26, 29, 33, and 34.-The cytoplasms and the chromosomes (other than the second chromosomes) were made approximately uniform throughout the experiments. Thus, this remarkable variability in the occurrence rate is most probably due to the differences in one or more chromosomal elements on the original five stem chromosomes. The mutable chromosomes (AW and JH) appear to carry a kind of mutator factor such as hi (Ives 1950).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218183"} {"pmid": "4218184", "title": "Sideroblastic anaemia and jejunal diverticulosis.", "content": "Sideroblastic anaemia and jejunal diverticulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218184"} {"pmid": "4218185", "title": "Reversibility of atherosclerosis.", "content": "Reversibility of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218185"} {"pmid": "4218186", "title": "Partial unilateral lentiginosis with associated developmental abnormalities.", "content": "Partial unilateral lentiginosis with associated developmental abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218186"} {"pmid": "4218187", "title": "The role of radical hysterectomy in adenocarcinoma of the endometrium.", "content": "The role of radical hysterectomy in adenocarcinoma of the endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218187"} {"pmid": "4218188", "title": "Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria.", "content": "Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218188"} {"pmid": "4218189", "title": "Autoradiographic and cytophotometric studies on granulocyte precursors in chronic myeloid leukaemia.", "content": "Autoradiographic and cytophotometric studies on granulocyte precursors in chronic myeloid leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218189"} {"pmid": "4218192", "title": "[Chronic idiopathic acquired hypogammaglobulinemia with hypersplenism, sarcoid-like arthritis and dermatomyositis. Report of a case (author's transl)].", "content": "[Chronic idiopathic acquired hypogammaglobulinemia with hypersplenism, sarcoid-like arthritis and dermatomyositis. Report of a case (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218192"} {"pmid": "4218195", "title": "Changes in the neurosecretory apparatus of protein malnurished rats.", "content": "Changes in the neurosecretory apparatus of protein malnurished rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218195"} {"pmid": "4218203", "title": "Effects of radiations on the rate of regeneration in Homalozoon vermiculare (STokes) & Urostyla.", "content": "Effects of radiations on the rate of regeneration in Homalozoon vermiculare (STokes) & Urostyla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218203"} {"pmid": "4218204", "title": "'Diverticulosis' of the fish duodenum infested with cestodes.", "content": "'Diverticulosis' of the fish duodenum infested with cestodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218204"} {"pmid": "4218205", "title": "Pseudomonas aeruginosa in post operative wound infection.", "content": "Pseudomonas aeruginosa in post operative wound infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218205"} {"pmid": "4218206", "title": "Perinatal observations of mother-infant behaviour in the bonnet macaque.", "content": "Perinatal observations of mother-infant behaviour in the bonnet macaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218206"} {"pmid": "4218207", "title": "Case studies in bioethics. Saying \"no\" to hemodialysis. Should a minor's decision be respected?", "content": "Case studies in bioethics. Saying \"no\" to hemodialysis. Should a minor's decision be respected?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218207"} {"pmid": "4218208", "title": "A translocation in cattle and its association to polymorphisms in red cell antigens, transferrins and carbonic anhydrases.", "content": "A translocation in cattle and its association to polymorphisms in red cell antigens, transferrins and carbonic anhydrases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218208"} {"pmid": "4218209", "title": "Cytogenetical localization of the amylase region in Drosophila melanogaster by means of translocations.", "content": "Cytogenetical localization of the amylase region in Drosophila melanogaster by means of translocations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218209"} {"pmid": "4218210", "title": "Position-effect variegation for an isoamylase in Drosophila melanogaster.", "content": "Position-effect variegation for an isoamylase in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218210"} {"pmid": "4218211", "title": "Puffing pattern of 0-hour prepupae of Drosophila melanogaster.", "content": "Puffing pattern of 0-hour prepupae of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218211"} {"pmid": "4218213", "title": "Whole mount electron microscopy of core fibrils in salivary-gland chromosomes of Drosophila melanogaster.", "content": "Whole mount electron microscopy of core fibrils in salivary-gland chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218213"} {"pmid": "4218212", "title": "H3-thymidine radioautography of salivary gland chromosomes treated with alkali-urea.", "content": "H3-thymidine radioautography of salivary gland chromosomes treated with alkali-urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218212"} {"pmid": "4218214", "title": "Population studies in northern Sweden. III. Variations of ABO and Rh blood group gene frequencies in time and space.", "content": "Population studies in northern Sweden. III. Variations of ABO and Rh blood group gene frequencies in time and space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218214"} {"pmid": "4218215", "title": "Interchromosomal effects of autosomal inversions in Drosophila melanogaster.", "content": "Interchromosomal effects of autosomal inversions in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218215"} {"pmid": "4218216", "title": "The effect of the Curly inversions on meiosis in Drosophila melanogaster. III. Interchromosomal effect of homozygous inversions.", "content": "The effect of the Curly inversions on meiosis in Drosophila melanogaster. III. Interchromosomal effect of homozygous inversions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218216"} {"pmid": "4218217", "title": "Factors influencing the competitive ability of certain wild stocks of Drosophila.", "content": "Factors influencing the competitive ability of certain wild stocks of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218217"} {"pmid": "4218218", "title": "The biochemical genetics of rudimentary mutants of Drosophila melanogaster. I. Aspartate carbamoyltransferase levels in complementing and non-complementing strains.", "content": "The biochemical genetics of rudimentary mutants of Drosophila melanogaster. I. Aspartate carbamoyltransferase levels in complementing and non-complementing strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218218"} {"pmid": "4218219", "title": "Whole mount electron microscopy of small chromomeres in salivary gland chromosomes of Drosophila melanogaster.", "content": "Whole mount electron microscopy of small chromomeres in salivary gland chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218219"} {"pmid": "4218220", "title": "Whole mount electron microscopy of fibril-rings in alkali-urea treated salivary gland chromosomes of Drosophila melanogaster.", "content": "Whole mount electron microscopy of fibril-rings in alkali-urea treated salivary gland chromosomes of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218220"} {"pmid": "4218221", "title": "Female meiosis and embryonic mitosis in Drosophila melanogaster. I. Meiosis and fertilization.", "content": "Female meiosis and embryonic mitosis in Drosophila melanogaster. I. Meiosis and fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218221"} {"pmid": "4218222", "title": "Fitness and fitness components for a two-allele system in Drosophila melanogaster.", "content": "Fitness and fitness components for a two-allele system in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218222"} {"pmid": "4218223", "title": "Exogenous acetylcholinesterase as tracer for extracellular pathways in the brain.", "content": "Exogenous acetylcholinesterase as tracer for extracellular pathways in the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218223"} {"pmid": "4218224", "title": "Histochemical demonstration of the intestinal hetero-beta-galactosidase (glucosidase).", "content": "Histochemical demonstration of the intestinal hetero-beta-galactosidase (glucosidase).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218224"} {"pmid": "4218225", "title": "Antimetabolites produced by microorganisms. XI. 1-(S)-hydroxy-2-(S,S)-valylamido-cyclobutane-1-acetic acid.", "content": "Antimetabolites produced by microorganisms. XI. 1-(S)-hydroxy-2-(S,S)-valylamido-cyclobutane-1-acetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218225"} {"pmid": "4218226", "title": "Editorial: Diabetes in the young.", "content": "Editorial: Diabetes in the young.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218226"} {"pmid": "4218227", "title": "Completed chromosomes in thymine-requiring Bacillus subtilis spores.", "content": "Completed chromosomes in thymine-requiring Bacillus subtilis spores. Origin:terminus genetic marker ratios (both purA: metB and purA:ilvA) were measured in extracts of spores of Bacillus subtilis strains W23 thy his and 168 thy. For strain W23 thy his, normalized to W23 spore deoxyribonucleic acid, both ratios were equal to unity and were consistent with the presence of only completed chromosomes in the spores. The same ratios in extracts of spores of 168 thy, normalized to strain 168 or the prototroph SB19, were abnormal, i.e., 2.26 +/- 0.10 and 0.71 +/- 0.06 for purA:metB and purA:ilvA, respectively. These values were unaffected by the extent of extraction of the spore deoxyribonucleic acid, the richness of the medium on which they are formed, and the thymine phenotype. The high ratio for purA:metB is in agreement with the results of earlier workers but, because of the low purA:ilvA ratio, cannot be explained simply by the presence of partially replicated chromosomes in spores of strain 168 thy. Furthermore, purA:leuA in such extracts is 1.01 +/- 0.06, consistent with the presence of only completed chromosomes. It is concluded that the abnormal origin:terminus marker ratios are only apparent and result from non-isogenicity between strains 168 thy and 168 in the metB thyB ilvA chromosome region introduced during construction of 168 thy by transformation of strain 168 with W23 thy deoxyribonucleic acid. It is concluded further that the chromosomes of strain 168 thy spores are in a completed form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218227"} {"pmid": "4218228", "title": "Purification and properties of 3-deoxy-D-arabionheptulosonic acid-7-phosphate synthetase (trp) from Escherichia coli.", "content": "Purification and properties of 3-deoxy-D-arabionheptulosonic acid-7-phosphate synthetase (trp) from Escherichia coli. The 3-deoxy-d-arabinoheptulosonic acid-7-phosphate synthetase which is subject to regulation by tryptophan has been partially purified from a strain of Escherichia coli K-12, in which this is the only functional form of this enzyme activity, and from a similar strain possessing a feedback-resistant form of the enzyme. Maximal observed inhibition by tryptophan of the feedback-sensitive enzyme was 56%. There was no evidence for cooperativity in the saturation of the enzyme with tryptophan or E4P. The molecular weights of the feedback-sensitive and feedback-resistant forms of the enzyme were the same (52,000), and no change was detected in the molecular weight of the feedback-sensitve enzyme in the presence of tryptophan. The effect of tryptophan analogues was tested to determine the nature of the tryptophan binding site. Treatment with ethylenediaminetetraacetic acid removed 80% of the activity of the feedback-sensitive enzyme. This activity was restored upon the addition of Co(2+) or Mn(2+). Neither treatment with ethylenediaminetetraacetic acid nor addition of Co(2+) or Mn(2+) affected the activity of the feedback-resistant enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218228"} {"pmid": "4218229", "title": "Lipopolysaccharide containing L-acofriose in the filamentous blue-green alga Anabaena variabilis.", "content": "Lipopolysaccharide containing L-acofriose in the filamentous blue-green alga Anabaena variabilis. For the first time, an O-antigenic lipopolysaccharide (LPS) has been isolated from a filamentous blue-green alga (Anabaena variabilis). It was extractable with phenol-water, resulting in extraction of the bulk of the LPS into the phenol phase. The polysaccharide moiety of this LPS consists of l-rhamnose, its 3-O-methyl ether l-acofriose, d-mannose, d-glucose, and d-galactose. l-Glycero-d-mannoheptose and 2-keto-3-deoxyoctonate, the two characteristic sugar components of enteric LPS, and phosphate groups are absent from the A. variabilis O antigen. The only amino sugar present is d-glucosamine. Three hydroxy fatty acids were identified, namely, beta-hydroxymyristic, beta-hydroxypalmitic and beta-hydroxystearic acids, in addition to palmitic and unidentified fatty acid. The LPS of A. variabilis is localized in the outermost cell wall layer and behaves like a bacterial O antigen in serological tests. The passive hemagglutination yielded high titers with isolated LPS (pretreated by heat or by alkali) and rabbit antisera prepared against living or heat-killed cells. The position of the precipitation arcs after immunoelectrophoresis of the O antigen indicates the lack of charged groups. The water phase of the phenol-water extract contains, in high yield, a glucose polymer. It is serologically inactive as shown by the passive hemagglutination test and by agar-gel precipitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218229"} {"pmid": "4218230", "title": "Activation of inactive nitrogenase by acid-treated component I.", "content": "Activation of inactive nitrogenase by acid-treated component I. When Azotobacter vinelandii was derepressed for nitrogenase synthesis in a N-free medium containing tungstate instead of molybdate, an inactive component I was synthesized. Although this inactive component I could be activated in vivo upon addition of molybdate to the medium, it could not be activated in vitro when molybdate was added to the extracts. Activation occurred, however, when an acid-treated component I was added to extracts of cells derepressed in medium containing tungstate. Acid treatment completely abolished component I activity. Mutant strains UW45 and UW10 were unable to fix N(2). Both strains synthesized normal levels of component II but produced inactive component I. Acid-treated component I activated inactive component I in extracts of mutant strain UW45 but not mutant strain UW10. This activating factor could be obtained from N(2)-fixing Klebsiella pneumoniae, Clostridium pasteurianum, and Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218230"} {"pmid": "4218231", "title": "Glycerolphosphate-containing cell wall polysaccharides from Streptococcus sanguis.", "content": "Glycerolphosphate-containing cell wall polysaccharides from Streptococcus sanguis. Six glycerolphosphate-containing tetraheteroglycans, a, b-1, b-2, b-3, b-4, and b-5, have been purified from the formamide extracts of Streptococcus sanguis by alcohol and acetone precipitations, Sephadex G-75, and diethylaminoethyl-cellulose column chromatography. The polysaccharides were judged as at least 95% pure by analytical disc gel electrophoresis and immune double diffusion against rabbit antiserum. They were shown to be cell wall polysaccharides, since they formed a single band of identity in immune double diffusion with partially purified polysaccharide extracted from a purified cell wall preparation of S. sanguis. The polysaccharides were composed of l-rhamnose, d-glucose, and N-acetyl d-glucosamine in a similar molar ratio, but varied in their glycerol and phosphate contents. They exhibited four different mobilities in polyacrylamide disc gel electrophoresis at pH 8.9. When they were treated with formamide at 170 C for 20 min, the faster moving polysaccharide(s) yielded polysaccharides with mobilities corresponding to the other slower moving polysaccharides. These results indicate that the polysaccharides originated from the same cell wall polysaccharide and were produced as a result of breakage in the phosphodiester bonds during the formamide extraction procedure. A preliminary structural study shows that the terminal reducing sugar is l-rhamnose and that the glycerol moiety is probably linked to the polysaccharide through a phosphodiester bond.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218231"} {"pmid": "4218232", "title": "Characterization of a bacteriophage-induced, host-specific lytic enzyme from lysates of Bacillus stearothermophilus infected with bacteriophage TP-8.", "content": "Characterization of a bacteriophage-induced, host-specific lytic enzyme from lysates of Bacillus stearothermophilus infected with bacteriophage TP-8. Phage TP-8 lysates of Bacillus stearothermophilus 4S or 4S(8) contain lytic activity exhibiting two pH optima, one at pH 6.5 and the other at pH 7.5. Using a variety of fractionation procedures, the two lytic activities could not be separated. At pH 7.5 the lytic enzyme is an endopeptidase which hydrolyzes the l-alanyl-d-glutamyl linkage in the peptide subunits of the cell wall peptidoglycan and at pH 6.5 it exhibits N-acetylmuramidase activity. Endopeptidase activity is inhibited by NaCl and neither lytic activity was significantly affected by divalent cations or ethylenediaminetetraacetic acid. Crude lysates contain 2.5 to 3.0 times more endopeptidase activity than N-acetylmuramidase activity. The ratio of the two lytic activities (endopeptidase/N-acetylmuramidase) changes to 1.3 to 1.7 during the course of purification, to 1.0 after isoelectric focusing, and 3.9 and 6.00 after exposure for 2 h at 60 and 65 C, respectively. We conclude that the two lytic activities may be associated with a single protein or a lytic enzyme complex composed of two enzymes. Lytic activity at pH 7.5 is more effective in solubilizing cells or cell walls than the lytic activity at pH 6.5. LiCl extracts of 4S and 4S(8) cells contain lytic activity exhibiting endopeptidase activity at pH 7.5 and N-acetylmuramidase activity at pH 6.5. Lytic activity in these LiCl extracts also has a number of other properties in common with those in lysates of phage TP-8. We proposed that the lytic enzyme(s) are not coded for by the phage genome but are part of the host autolytic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218232"} {"pmid": "4218234", "title": "Properties of thermosensitive extracellular alpha-amylases of Bacillus subtilis.", "content": "Properties of thermosensitive extracellular alpha-amylases of Bacillus subtilis. Enzymological properties of four thermosensitive alpha-amylases (M3, M9, M18, and M20) brought by different mutation sites in alpha-amylase structural gene of Bacillus subtilis were compared with those of the parental alpha-amylase NA64. Two thermosensitive alpha-amylases (M9 and M20) were altered not only in their thermosensitivity but also in their immunological properties, catalytic properties, molecular weights determined by the gel filtration on a Bio-Gel P-100 column, and others. The other two thermosensitive alpha-amylases (M3 and M18) were altered only in their thermosensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218234"} {"pmid": "4218233", "title": "Thermal death of temperature-sensitive lysyl- and tryptophanyl-transfer ribonucleic acid synthetase mutants of Bacillus subtilis: effect of culture medium and developmental stage.", "content": "Thermal death of temperature-sensitive lysyl- and tryptophanyl-transfer ribonucleic acid synthetase mutants of Bacillus subtilis: effect of culture medium and developmental stage. The growth of thermosensitive Bacillus subtilis lysyl- and tryptophanyl-transfer ribonucleic acid synthetase mutants (lysS1 and trypS1) (l-lysine:transfer ribonucleic acid [tRNA] ligase [AMP], EC 6.1.1.6; and l-tryptophan:tRNA ligase [AMP], EC 6.1.1.2) was terminated when exponential phase cells were shifted from 30 to 43 C in a rich medium. Under these conditions, the temperature-inhibited cells undergo thermal death; they rapidly lose their ability to form colonies at 30 C. Another lysyl-tRNA synthetase mutant (lysS2) is refractory to thermal death even though its growth is inhibited at 43 C. The thermal death response of the lysS1 mutant is affected by the stage of cell development. At periods in spore outgrowth and sporogenesis these cells become refractory to thermal death. The refractory state does not result from the production of an inhibitor, or from the degradation of an activator of thermal death. However, culture medium composition does modify the thermal death response. Rich media enhance the effect, and no thermal death occurs in the lysS1 strain grown in a minimal medium. Temperature-sensitive cells can grow in a lysine- (0.25 mM) or tryptophan- (0.25 mM) supplemented minimal medium at 43 C, but amino acid concentrations of 25 mM only transiently protect trypS1 and lysS1 cells from thermal death in a rich medium. Osmotic agents such as sucrose (0.5 M) and NaCl (0.34 M) completely prevent thermal death in the lysS1 strain, although growth is still arrested. On solid media, sucrose stabilized lysS1 cells can form colonies at the restrictive temperature, but neither sucrose (0.5 M) nor NaCl (0.34 M) stabilized the lysS1 enzyme in vitro. Chloramiphenicol increased the rate of thermal death of the lysS1 strain but decreased the thermal death response of the trypS1 mutant. Considering the nature of the enzyme defect in the lysS1 strain, the common genetic origin of the spore and vegetative lysyl-tRNA synthetase, and the protective effects exerted by lysine and osmotic agents, it is tentatively concluded that thermal death results from irreversible inactivation of the mutant gene product. According to this hypothesis, either the lysS1 enzyme is altered during sporogenesis or some physiological or structural aspect of this developmental phase can stabilize the mutant phenotype and thereby rescue cells from thermal death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218233"} {"pmid": "4218237", "title": "Pyrolytic biocarbon materials.", "content": "Pyrolytic biocarbon materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218237"} {"pmid": "4218236", "title": "Extracellular enzyme from Myxobacter AL-1 that exhibits both beta-1,4-glucanase and chitosanase activites.", "content": "Extracellular enzyme from Myxobacter AL-1 that exhibits both beta-1,4-glucanase and chitosanase activites. An enzyme that has both beta-1,4-glucanase and chitosanase activities is characterized. Evidence for homogeneity was obtained from electrophoresis and sedimentation velocity studies; only one N-terminal amino acid, valine, was found. Results of denaturation studies showed that beta-1,4-glucanase and chitosanase activities decreased at equal rates. With carboxymethylcellulose as the substrate, a K(m) of 1.68 g of carboxymethylcellulose per liter of solution and a V(max) of 2.20 x 10(-9) mol/min were found. With chitosan (the beta-1,4-polymer of glucosamine) as the substrate, a K(m) of 0.30 g of chitosan per liter of solution and a V(max) of 0.75 x 10(-9) mol/min were found. A pH optimum of 5.0 was found for beta-1,4-glucanase activity, and pH optima of 5.0 and 6.8 were found for chitosanase activity. beta-1,4-Glucanase activity had a temperature optimum of 38 C, and chitosanase activity had a temperature optimum of 70 C. Chitosan stabilized both enzyme activities at 70 C. Cellotriose was the smallest polymer capable of hydrolysis. Glucosamine was released by action of the enzyme upon cell wall preparations of several fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218236"} {"pmid": "4218235", "title": "In vivo kinetics of nitrogenase formation in Clostridium pasteurianum.", "content": "In vivo kinetics of nitrogenase formation in Clostridium pasteurianum. Clostridium pasteurianum exhibits diauxic growth when grown in the presence of both NH(3) and N(2); no nitrogenase activity or formation was detected either serologically or by activity during growth on NH(3). During the 60-min lag that ensued after NH(3) was consumed and before growth resumed, molybdoferredoxin and azoferredoxin were first detected by activity measurements and serologically at 25 and 40 min, respectively. With the use of rifampin and dactinomycin, it was found that azoferredoxin messenger ribonucleic acid was initiated between 25 and 30 min after the inception of the lag and was completed by 38 min. An explanation of these results and their relation to possible models for the regulation of nitrogenase is given.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218235"} {"pmid": "4218238", "title": "The components of \"affectionless psychopathy in institutionalized children.", "content": "The components of \"affectionless psychopathy in institutionalized children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218238"} {"pmid": "4218240", "title": "Scrapie--a personal view.", "content": "Scrapie--a personal view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218240"} {"pmid": "4218239", "title": "Host-virus relationship with special reference to Newcastle disease and serum hepatitis.", "content": "Host-virus relationship with special reference to Newcastle disease and serum hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218239"} {"pmid": "4218241", "title": "Amyotrophic lateral sclerosis, Parkinson's disease, and the amyotrophic lateral sclerosis-Parkinsonism-dementia complex on Guam: a review and summary of attempts to demonstrate infection as the aetiology.", "content": "Amyotrophic lateral sclerosis, Parkinson's disease, and the amyotrophic lateral sclerosis-Parkinsonism-dementia complex on Guam: a review and summary of attempts to demonstrate infection as the aetiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218241"} {"pmid": "4218242", "title": "Membrane hypothesis of scrapie.", "content": "Membrane hypothesis of scrapie.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218242"} {"pmid": "4218243", "title": "The nature of the scrapie agent.", "content": "The nature of the scrapie agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218243"} {"pmid": "4218244", "title": "Isolation and characterization of the subacute spongiform virus encephalopathies of man: kuru and Creutzfeldt-Jakob disease.", "content": "Isolation and characterization of the subacute spongiform virus encephalopathies of man: kuru and Creutzfeldt-Jakob disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218244"} {"pmid": "4218245", "title": "Response of whole-body irradiated mice to inoculation of Theileria parva-infected bovine lymphoid cells.", "content": "Response of whole-body irradiated mice to inoculation of Theileria parva-infected bovine lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218245"} {"pmid": "4218247", "title": "Three cases of suspected mammary neoplasia in non-human primates.", "content": "Three cases of suspected mammary neoplasia in non-human primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218247"} {"pmid": "4218246", "title": "Erythrocyte losses from pigs with experimental Trichuris suis infections measured with a whole-body counter.", "content": "Erythrocyte losses from pigs with experimental Trichuris suis infections measured with a whole-body counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218246"} {"pmid": "4218248", "title": "The ectopic mandibular second molar.", "content": "The ectopic mandibular second molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218248"} {"pmid": "4218250", "title": "A new method of preparation of specifically purified anti-TNP antibodies.", "content": "A new method of preparation of specifically purified anti-TNP antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218250"} {"pmid": "4218249", "title": "Antibodies to endotoxin from Vibrio cholerae measured by bactericidal and indirect hemagglutination tests. Differences in immunoglobulin classes and specificity.", "content": "Antibodies to endotoxin from Vibrio cholerae measured by bactericidal and indirect hemagglutination tests. Differences in immunoglobulin classes and specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218249"} {"pmid": "4218252", "title": "Isoelectric focusing of rabbit IgM hemolysin: heterogeneity with respect to charge and function.", "content": "Isoelectric focusing of rabbit IgM hemolysin: heterogeneity with respect to charge and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218252"} {"pmid": "4218251", "title": "Haemolytic assay of bovine serum complement.", "content": "Haemolytic assay of bovine serum complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218251"} {"pmid": "4218260", "title": "Polychlorobiphenyl toxicity and nutrition. II. PCB toxicity and vitamin A (2).", "content": "Polychlorobiphenyl toxicity and nutrition. II. PCB toxicity and vitamin A (2).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218260"} {"pmid": "4218262", "title": "Proceedings: The release of thyrotrophin in response to thyrotrophin releasing hormone (TRH) in the pregnant ewe, lamb foetus and neonatal lamb.", "content": "Proceedings: The release of thyrotrophin in response to thyrotrophin releasing hormone (TRH) in the pregnant ewe, lamb foetus and neonatal lamb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218262"} {"pmid": "4218263", "title": "Proceedings: Dorsal horn neurons excited by cutaneous cold receptors in primates.", "content": "Proceedings: Dorsal horn neurons excited by cutaneous cold receptors in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218263"} {"pmid": "4218264", "title": "Cancers of the larynx and hypopharynx. II. Laryngeal cartilage behaviour.", "content": "Cancers of the larynx and hypopharynx. II. Laryngeal cartilage behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218264"} {"pmid": "4218259", "title": "Focal EEG in post-traumatic mild coma. Follow-up study on unoperated patients.", "content": "Focal EEG in post-traumatic mild coma. Follow-up study on unoperated patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218259"} {"pmid": "4218267", "title": "The relationship between listericidal and mycobacteriostatic activity in BCG-vaccinated mice.", "content": "The relationship between listericidal and mycobacteriostatic activity in BCG-vaccinated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218267"} {"pmid": "4218268", "title": "Treatment of juvenile rheumatoid arthritis -- a world survey.", "content": "Treatment of juvenile rheumatoid arthritis -- a world survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218268"} {"pmid": "4218283", "title": "Studies on the live attenuated rubella virus vaccine. II. Research concerning attenuation of \"Takahashi strain\" isolated in Japan.", "content": "Studies on the live attenuated rubella virus vaccine. II. Research concerning attenuation of \"Takahashi strain\" isolated in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218283"} {"pmid": "4218286", "title": "Interaction between glucocorticoids and TSH secretion.", "content": "Interaction between glucocorticoids and TSH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218286"} {"pmid": "4218285", "title": "Immune response in patients with autoimmune thrombocytopenia and autoimmune haemolytic anaemia receiving azathioprine.", "content": "Immune response in patients with autoimmune thrombocytopenia and autoimmune haemolytic anaemia receiving azathioprine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218285"} {"pmid": "4218287", "title": "Clinical observations on therapeutic applications of thyrotropin-releasing hormone (TRH).", "content": "Clinical observations on therapeutic applications of thyrotropin-releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218287"} {"pmid": "4218292", "title": "Two minutes with diabetes.", "content": "Two minutes with diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218292"} {"pmid": "4218301", "title": "Functional diversity within the rudimentary locus of Drosophila melanogaster.", "content": "Functional diversity within the rudimentary locus of Drosophila melanogaster. The rudimentary locus of Drosophila melanogaster is shown to be at least bifunctional. Mutants in different regions of the locus have either no CPSase or no ATCase activity; some mutants lack both activities. The results are discussed in correlation with the complementation and genetic map of the locus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218301"} {"pmid": "4218303", "title": "A meiotic effect of a mutator gene in Drosophila melanogaster.", "content": "A meiotic effect of a mutator gene in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218303"} {"pmid": "4218304", "title": "Vulture retina enzyme distribution and function.", "content": "Vulture retina enzyme distribution and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218304"} {"pmid": "4218293", "title": "Effect of eight tetracyclines on growth and lipase formation of Staphylococcus aureus.", "content": "Effect of eight tetracyclines on growth and lipase formation of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218293"} {"pmid": "4218297", "title": "Immunity to influenza in ferrets. IX. Delayed hypersensitivity following infection or immunization with A2/Hong Kong virus.", "content": "Immunity to influenza in ferrets. IX. Delayed hypersensitivity following infection or immunization with A2/Hong Kong virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218297"} {"pmid": "4218305", "title": "On the cleavage of starch and disaccharides in the human oral cavity.", "content": "On the cleavage of starch and disaccharides in the human oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218305"} {"pmid": "4218294", "title": "Surface properties of cells of gentamicin-sensitive and gentamicin-resistant strains of Pseudomonas aeruginosa.", "content": "Surface properties of cells of gentamicin-sensitive and gentamicin-resistant strains of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218294"} {"pmid": "4218295", "title": "Influence of growth conditions on the formic: acetic acid ratio in Escherichia coli and Streptococcus faecalis.", "content": "Influence of growth conditions on the formic: acetic acid ratio in Escherichia coli and Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218295"} {"pmid": "4218296", "title": "The anti-proteins in Salmonella monofactor sera.", "content": "The anti-proteins in Salmonella monofactor sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218296"} {"pmid": "4218312", "title": "Autonomic and behavioral temperature regulation. Unilateral vs bilateral preoptic thermal stimulation.", "content": "Autonomic and behavioral temperature regulation. Unilateral vs bilateral preoptic thermal stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218312"} {"pmid": "4218315", "title": "Ryle's tube. John Ryle (1889-1950).", "content": "Ryle's tube. John Ryle (1889-1950).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218315"} {"pmid": "4218316", "title": "Repeat prescription cards.", "content": "Repeat prescription cards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218316"} {"pmid": "4218307", "title": "A case of paratyphoid fever accidentally treated with amoxycillin. (Case report).", "content": "A case of paratyphoid fever accidentally treated with amoxycillin. (Case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218307"} {"pmid": "4218329", "title": "The use of intestinal markers to measure digestive function in ruminants.", "content": "The use of intestinal markers to measure digestive function in ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218329"} {"pmid": "4218330", "title": "Proceedings: Linolenic acid deprivation in Capuchin monkeys.", "content": "Proceedings: Linolenic acid deprivation in Capuchin monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218330"} {"pmid": "4218331", "title": "Proceedings: Lipid composition of human milk: comparative studies on African and European mothers.", "content": "Proceedings: Lipid composition of human milk: comparative studies on African and European mothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218331"} {"pmid": "4218332", "title": "Immunodepressive effects of combination chemotherapy with N-diazoacetylglycine amide, L-asparaginase, and cortisone, in mice.", "content": "Immunodepressive effects of combination chemotherapy with N-diazoacetylglycine amide, L-asparaginase, and cortisone, in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218332"} {"pmid": "4218333", "title": "Central nervous system toxic manifestations of sodium cyanate.", "content": "Central nervous system toxic manifestations of sodium cyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218333"} {"pmid": "4218335", "title": "Glycogen in the central nervous system.", "content": "Glycogen in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218335"} {"pmid": "4218306", "title": "New aspects of malnutrition in Jakarta.", "content": "New aspects of malnutrition in Jakarta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218306"} {"pmid": "4218337", "title": "Reversal by Pseudomonas aeruginosa of rifamycin SV inhibition of Staphylococcus aureus in vitro and in vivo.", "content": "Reversal by Pseudomonas aeruginosa of rifamycin SV inhibition of Staphylococcus aureus in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218337"} {"pmid": "4218343", "title": "Letter: Enhancement of E-rosettes formation after treatment of lymphocytes with papain.", "content": "Letter: Enhancement of E-rosettes formation after treatment of lymphocytes with papain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218343"} {"pmid": "4218344", "title": "Increased phosphorylation of nuclear phosphoproteins in precancerous liver.", "content": "Increased phosphorylation of nuclear phosphoproteins in precancerous liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218344"} {"pmid": "4218336", "title": "Radial immunoassay of erythrocyte carbonic anhydrase enzymes: a screening procedure to detect megaloblastic erythropoiesis.", "content": "Radial immunoassay of erythrocyte carbonic anhydrase enzymes: a screening procedure to detect megaloblastic erythropoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218336"} {"pmid": "4218356", "title": "Experimental bases of chronic lung diseases.", "content": "Experimental bases of chronic lung diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218356"} {"pmid": "4218358", "title": "Cold induced retraction of reptilase clots.", "content": "Cold induced retraction of reptilase clots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218358"} {"pmid": "4218359", "title": "Platelet factor 4 (PF-4). An electroimmuno assay for PF-4 in human plasma.", "content": "Platelet factor 4 (PF-4). An electroimmuno assay for PF-4 in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218359"} {"pmid": "4218347", "title": "Role of some elements on the enzymatic transformation of cortisol with Bacillus cereus.", "content": "Role of some elements on the enzymatic transformation of cortisol with Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218347"} {"pmid": "4218360", "title": "Human secretory component. II. Physicochemical characterization of free secretory component purified from colostrum.", "content": "Human secretory component. II. Physicochemical characterization of free secretory component purified from colostrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218360"} {"pmid": "4218361", "title": "IgM reassociation in Vitro: no influence of J chain on the amount of polymers.", "content": "IgM reassociation in Vitro: no influence of J chain on the amount of polymers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218361"} {"pmid": "4218362", "title": "Antibody-dependent cell-mediated cytotoxicity in the mouse. I. Surface characteristics of an effecter cell.", "content": "Antibody-dependent cell-mediated cytotoxicity in the mouse. I. Surface characteristics of an effecter cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218362"} {"pmid": "4218363", "title": "Comparative study of antibody-dependent and direct lymphocyte-mediated cytotoxicity in vitro after alloimmunization in the human. II. Chemical inhibitors.", "content": "Comparative study of antibody-dependent and direct lymphocyte-mediated cytotoxicity in vitro after alloimmunization in the human. II. Chemical inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218363"} {"pmid": "4218364", "title": "N-terminal amino acid sequence of amyloid fibril protein AR, prototype of a new lambda-variable subgroup, V lambda V.", "content": "N-terminal amino acid sequence of amyloid fibril protein AR, prototype of a new lambda-variable subgroup, V lambda V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218364"} {"pmid": "4218365", "title": "Surface IgD in immunoproliferative disorders.", "content": "Surface IgD in immunoproliferative disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218365"} {"pmid": "4218366", "title": "A monoclonal IgG protein with antibody-like activity for transferrin and with kappa chains of an unusual molecular size.", "content": "A monoclonal IgG protein with antibody-like activity for transferrin and with kappa chains of an unusual molecular size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218366"} {"pmid": "4218367", "title": "Comparison of Fch and Fc fragments of IgG3: evidence of an intra-chain S-S bridge in the hinge of gamma3 chains.", "content": "Comparison of Fch and Fc fragments of IgG3: evidence of an intra-chain S-S bridge in the hinge of gamma3 chains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218367"} {"pmid": "4218369", "title": "Pathophysiology of Cholelithiasis.", "content": "Pathophysiology of Cholelithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218369"} {"pmid": "4218368", "title": "The tuberculosis morbidity among pathologists in Finland.", "content": "The tuberculosis morbidity among pathologists in Finland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218368"} {"pmid": "4218354", "title": "Experimental chemotherapy of schistosomiasis. VII. Laboratory and clinical trials with sodium antimony dimethylcysteine tartrate (NaP).", "content": "Experimental chemotherapy of schistosomiasis. VII. Laboratory and clinical trials with sodium antimony dimethylcysteine tartrate (NaP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218354"} {"pmid": "4218373", "title": "The relationship between protein-calorie malnutrition and trichinosis: 1. Studies on the number of intestinal worms and muscular larvae in rats fed low and high protein diets.", "content": "The relationship between protein-calorie malnutrition and trichinosis: 1. Studies on the number of intestinal worms and muscular larvae in rats fed low and high protein diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218373"} {"pmid": "4218375", "title": "Cardiac malformations and other effects due to insecticides in embryos of the killifish, Fundulus heteroclitus.", "content": "Cardiac malformations and other effects due to insecticides in embryos of the killifish, Fundulus heteroclitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218375"} {"pmid": "4218376", "title": "The effects of moderate hypoxia and moderate hypoxia plus hypercapnea on cardiac development in chick embryos.", "content": "The effects of moderate hypoxia and moderate hypoxia plus hypercapnea on cardiac development in chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218376"} {"pmid": "4218377", "title": "Properties of soluble fibrin polymers encountered in thrombotic states.", "content": "Properties of soluble fibrin polymers encountered in thrombotic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218377"} {"pmid": "4218379", "title": "Inactivation mechanism of tyrosinase.", "content": "Inactivation mechanism of tyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218379"} {"pmid": "4218380", "title": "B lymphocytes bearing immunoglobulins in multiple sclerosis.", "content": "B lymphocytes bearing immunoglobulins in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218380"} {"pmid": "4218381", "title": "Cross-neutralization by tiger snake (Notechis scutatus) antivenene and sea snake (Enhydrina schistosa) antivenene against several sea snake venoms.", "content": "Cross-neutralization by tiger snake (Notechis scutatus) antivenene and sea snake (Enhydrina schistosa) antivenene against several sea snake venoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218381"} {"pmid": "4218382", "title": "Studies on Egyptian Cerastes cerastes antivenin.", "content": "Studies on Egyptian Cerastes cerastes antivenin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218382"} {"pmid": "4218384", "title": "The mesosome--a clue to the evolution of the plasma membrane.", "content": "The mesosome--a clue to the evolution of the plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218384"} {"pmid": "4218385", "title": "Susceptibility of a new world monkey (Aotus trivirgatus) to an old world simian malarial parasite (Plasmodium knowlesi).", "content": "Susceptibility of a new world monkey (Aotus trivirgatus) to an old world simian malarial parasite (Plasmodium knowlesi).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218385"} {"pmid": "4218387", "title": "Letter: A skin test for the diagnosis of Chagas's disease.", "content": "Letter: A skin test for the diagnosis of Chagas's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218387"} {"pmid": "4218386", "title": "Rickettsioses in Australia: isolation of Rickettsia tsutsugamushi and R. australis from naturally infected arthropods.", "content": "Rickettsioses in Australia: isolation of Rickettsia tsutsugamushi and R. australis from naturally infected arthropods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218386"} {"pmid": "4218388", "title": "Letter: Serology of human sacosporidiosis.", "content": "Letter: Serology of human sacosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218388"} {"pmid": "4218389", "title": "Orthopaedic tuberculosis in the tropics.", "content": "Orthopaedic tuberculosis in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218389"} {"pmid": "4218390", "title": "Diabetes in Kenya.", "content": "Diabetes in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218390"} {"pmid": "4218391", "title": "Serum immunoglobulin patterns in South African population groups.", "content": "Serum immunoglobulin patterns in South African population groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218391"} {"pmid": "4218392", "title": "Folate levels in protein malnourished Nigerian children.", "content": "Folate levels in protein malnourished Nigerian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218392"} {"pmid": "4218397", "title": "Human immunity to gonococci: studies of opsonization by sera of prostitutes and nuns.", "content": "Human immunity to gonococci: studies of opsonization by sera of prostitutes and nuns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218397"} {"pmid": "4218404", "title": "A cytophotometric study of the DNA distribution in Ehrlich ascites tumour populations at different stages of development.", "content": "A cytophotometric study of the DNA distribution in Ehrlich ascites tumour populations at different stages of development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218404"} {"pmid": "4218405", "title": "Cytogenetic studies of ectopic pregnancies.", "content": "Cytogenetic studies of ectopic pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218405"} {"pmid": "4218408", "title": "Influence of X-irradiation on the different stages of the cell cycle in regenerating rat liver.", "content": "Influence of X-irradiation on the different stages of the cell cycle in regenerating rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218408"} {"pmid": "4218409", "title": "The diagnostic value of the DNA content of fine needle biopsies of the thyroid gland.", "content": "The diagnostic value of the DNA content of fine needle biopsies of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218409"} {"pmid": "4218411", "title": "Cultivation and survival studies of Neisseria gonorrhoeae in a human diploid cell strain.", "content": "Cultivation and survival studies of Neisseria gonorrhoeae in a human diploid cell strain. Neisseria gonorrhoeae was cultivated in a human diploid cell strain (WI-38). Eighty percent of the cultures contained viable gonococci for at least 4 m at 36°C, as evidenced by subculture to brain heart infusion broth. Monthly subcultures of bacteria could be made to fresh WI-38 cultures for at least 11 monthly passages with a 69% survival rate. The identity of gonococci was confirmed by morphology, gram staining, oxidase testing and fermentation reactions. Viability in brain heart infusion broth, minimum essential medium (Eagle), and WI-38 spent fluid was of much shorter duration. The organisms grown in WI-38 cultures appeared to orient largely in the vicinity of the WI-38 cells as well as within the cytoplasm of the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218411"} {"pmid": "4218421", "title": "Bacterial density in operation wounds.", "content": "Bacterial density in operation wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218421"} {"pmid": "4218422", "title": "Antisepsis of the operation site with aqueous cetrimide/chlorhexidine and chlorhexidine in alcohol.", "content": "Antisepsis of the operation site with aqueous cetrimide/chlorhexidine and chlorhexidine in alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218422"} {"pmid": "4218423", "title": "Aseptic barriers of plastic to prevent bacterial contamination of operation wounds.", "content": "Aseptic barriers of plastic to prevent bacterial contamination of operation wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218423"} {"pmid": "4218424", "title": "Experimental extracorporeal liver perfusion in vivo with daunomycin and 5-fluoro-uracil.", "content": "Experimental extracorporeal liver perfusion in vivo with daunomycin and 5-fluoro-uracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218424"} {"pmid": "4218425", "title": "Absorption of vitamin B12 in rats with jejuno-ileal transposition.", "content": "Absorption of vitamin B12 in rats with jejuno-ileal transposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218425"} {"pmid": "4218426", "title": "Duodenal diverticulum with intermittent biliary stasis.", "content": "Duodenal diverticulum with intermittent biliary stasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218426"} {"pmid": "4218429", "title": "Poly(A)-containing RNA molecules in electrophoretically separated fractions of rapidly labeled nuclear RNA from unstimulated and PHA-stimulated human lymphocytes.", "content": "Poly(A)-containing RNA molecules in electrophoretically separated fractions of rapidly labeled nuclear RNA from unstimulated and PHA-stimulated human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218429"} {"pmid": "4218430", "title": "Site of action of desferrioxamine in removing iron in normal and pathological conditions.", "content": "Site of action of desferrioxamine in removing iron in normal and pathological conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218430"} {"pmid": "4218431", "title": "Origin, morphologic and functional characteristics of a new lymphoid cell type in irradiated mouse bone marrow.", "content": "Origin, morphologic and functional characteristics of a new lymphoid cell type in irradiated mouse bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218431"} {"pmid": "4218432", "title": "The gamma-chain in a Ghanaian adult, homozygous for hereditary persistence of fetal haemoglobin.", "content": "The gamma-chain in a Ghanaian adult, homozygous for hereditary persistence of fetal haemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218432"} {"pmid": "4218433", "title": "Homozygous beta delta-thalassaemia. Description of a case and review of the literature.", "content": "Homozygous beta delta-thalassaemia. Description of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218433"} {"pmid": "4218434", "title": "Methods for measurement of the cerebral blood flow.", "content": "Methods for measurement of the cerebral blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218434"} {"pmid": "4218435", "title": "Some properties of proteolytic enzymes in human saliva.", "content": "Some properties of proteolytic enzymes in human saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218435"} {"pmid": "4218438", "title": "Gas chromatography of bacterial whole cell methanolysates; IV. A procedure for fractionation and identification of fatty acids and monosaccharides of cellular structures.", "content": "Gas chromatography of bacterial whole cell methanolysates; IV. A procedure for fractionation and identification of fatty acids and monosaccharides of cellular structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218438"} {"pmid": "4218436", "title": "A histochemical and electron microscopical study of so-called intravenous fat pigment.", "content": "A histochemical and electron microscopical study of so-called intravenous fat pigment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218436"} {"pmid": "4218437", "title": "Three autopsy cases of so-called neonatal necrotizing enterocolitis.", "content": "Three autopsy cases of so-called neonatal necrotizing enterocolitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218437"} {"pmid": "4218439", "title": "Gas chromatography of bacterial whole cell methanolysates; V. Fatty acid composition of Neisseriae and Moraxellae.", "content": "Gas chromatography of bacterial whole cell methanolysates; V. Fatty acid composition of Neisseriae and Moraxellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218439"} {"pmid": "4218440", "title": "Protein A production in different strains of Staphylococcus aureus under varied growth conditions.", "content": "Protein A production in different strains of Staphylococcus aureus under varied growth conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218440"} {"pmid": "4218441", "title": "Activities of some enzymes concerning pyruvate metabolism in Neisseria.", "content": "Activities of some enzymes concerning pyruvate metabolism in Neisseria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218441"} {"pmid": "4218443", "title": "Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine.", "content": "Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218443"} {"pmid": "4218442", "title": "Immunological comparison of NADP-dependent glutamate dehydrogenase and malate dehydrogenase in genus Neisseria.", "content": "Immunological comparison of NADP-dependent glutamate dehydrogenase and malate dehydrogenase in genus Neisseria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218442"} {"pmid": "4218444", "title": "Acetylsalicylic acid intolerance.", "content": "Acetylsalicylic acid intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218444"} {"pmid": "4218445", "title": "Epilepsy in the elderly.", "content": "Epilepsy in the elderly. Among 50 geriatric inpatients (average age 79) with late-onset epilepsy (average duration two years), 28 had grand mal attacks, 12 had focal attacks, seven had both. None had petit mal, confirming its rarity in the elderly. The epilepsy followed cerebrovascular disease (usually with hemiplegia) in 21 patients (8 per cent of all our patients with hemiplegia in the two-year study period developed epilepsy). Associated conditions included dementia in seven; and cerebral tumours (usually metastases) in five. This latter group survived less than two months on average from the onset of their attacks. The majority of patients (42 out of 50) were unfit for full neurological investigation; and the dangers of some procedures in the elderly are stressed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218445"} {"pmid": "4218446", "title": "Research in Coccidia and other Apicomplexa. A progress report.", "content": "Research in Coccidia and other Apicomplexa. A progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218446"} {"pmid": "4218449", "title": "Letter: Hyperalimentation procedures.", "content": "Letter: Hyperalimentation procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218449"} {"pmid": "4218450", "title": "Current drug therapy--antiepilepsy agents.", "content": "Current drug therapy--antiepilepsy agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218450"} {"pmid": "4218451", "title": "The adult respiratory distress syndrome.", "content": "The adult respiratory distress syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218451"} {"pmid": "4218459", "title": "Membrane-peptidoglycan association in the in vitro biosynthesis of the peptidoglycan of Micrococcus luteus.", "content": "Membrane-peptidoglycan association in the in vitro biosynthesis of the peptidoglycan of Micrococcus luteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218459"} {"pmid": "4218448", "title": "Disodium cromoglycate in the treatment of bronchial asthma. Study of 479 cases during ten months.", "content": "Disodium cromoglycate in the treatment of bronchial asthma. Study of 479 cases during ten months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218448"} {"pmid": "4218460", "title": "Phenotypic expression of an envC-division mutant of Escherichia coli K12.", "content": "Phenotypic expression of an envC-division mutant of Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218460"} {"pmid": "4218461", "title": "A change in cell diameter associated with an outer membrane lesion in a temperature-sensitive cell division mutant of Salmonella typhi-murium.", "content": "A change in cell diameter associated with an outer membrane lesion in a temperature-sensitive cell division mutant of Salmonella typhi-murium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218461"} {"pmid": "4218462", "title": "The role of divalent cations in the rigid layer of morphological and conditional mutant of Klebsiella pneumoniae Mir M7.", "content": "The role of divalent cations in the rigid layer of morphological and conditional mutant of Klebsiella pneumoniae Mir M7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218462"} {"pmid": "4218465", "title": "Functional disorders of the oesophagus. Roentgenological, cineradiographic and manometric study.", "content": "Functional disorders of the oesophagus. Roentgenological, cineradiographic and manometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218465"} {"pmid": "4218468", "title": "Behavioral responses to insect pheromones.", "content": "Behavioral responses to insect pheromones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218468"} {"pmid": "4218469", "title": "Insect nutrition: current developments and metabolic implications.", "content": "Insect nutrition: current developments and metabolic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218469"} {"pmid": "4218470", "title": "Neuro-hormonal control of sexual behavior in insects.", "content": "Neuro-hormonal control of sexual behavior in insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218470"} {"pmid": "4218474", "title": "Propylene oxide as sterilizing agent.", "content": "Propylene oxide as sterilizing agent. Liquid propylene oxide added to a variety of disinfectant solutions resulted in a significant reduction of the bacterial spore content of these solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218474"} {"pmid": "4218476", "title": "Influence of insecticide exposure on the in vivo and in vitro metabolic activity of rats.", "content": "Influence of insecticide exposure on the in vivo and in vitro metabolic activity of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218476"} {"pmid": "4218479", "title": "Gold therapy in rheumatoid arthritis.", "content": "Gold therapy in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218479"} {"pmid": "4218482", "title": "Is Sarcocystis tenella two species.", "content": "Is Sarcocystis tenella two species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218482"} {"pmid": "4218483", "title": "Alcohol dehydrogenase in Drosophila melanogaster: activity variation in natural populations.", "content": "Alcohol dehydrogenase in Drosophila melanogaster: activity variation in natural populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218483"} {"pmid": "4218484", "title": "Immunological relationships and post-translational modification of human salivary amylase (Amy) and pancreatic amylase (Amy) isozymes.", "content": "Immunological relationships and post-translational modification of human salivary amylase (Amy) and pancreatic amylase (Amy) isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218484"} {"pmid": "4218485", "title": "A method for determining diamine oxidase (histaminase) in biological fluids.", "content": "A method for determining diamine oxidase (histaminase) in biological fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218485"} {"pmid": "4218486", "title": "A method for assaying hepatic morphine UDP-glucuronyl transferase.", "content": "A method for assaying hepatic morphine UDP-glucuronyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218486"} {"pmid": "4218493", "title": "Present status of treatment of the mucopolysaccharidoses.", "content": "Present status of treatment of the mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218493"} {"pmid": "4218492", "title": "Cross pathway regulation of tyrosine and histidine synthesis in Bacillus subtilis. Biochemical, genetic, and transfer RNA studies.", "content": "Cross pathway regulation of tyrosine and histidine synthesis in Bacillus subtilis. Biochemical, genetic, and transfer RNA studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218492"} {"pmid": "4218494", "title": "Clinical heterogeneity in mucopolysaccharidosis. II. Evidence for epistasis.", "content": "Clinical heterogeneity in mucopolysaccharidosis. II. Evidence for epistasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218494"} {"pmid": "4218495", "title": "Stickler syndrome. Presenting as a syndrome of cleft palate, myopia and blindness inherited as a dominant trait.", "content": "Stickler syndrome. Presenting as a syndrome of cleft palate, myopia and blindness inherited as a dominant trait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218495"} {"pmid": "4218496", "title": "Case report. Case 2 (mucolipidosis III).", "content": "Case report. Case 2 (mucolipidosis III).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218496"} {"pmid": "4218499", "title": "Arousal effects on unit responsiveness to vocalizations in squirrel monkey auditory cortex.", "content": "Arousal effects on unit responsiveness to vocalizations in squirrel monkey auditory cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218499"} {"pmid": "4218500", "title": "Behavior in Drosophila melanogaster. A geneticist's view.", "content": "Behavior in Drosophila melanogaster. A geneticist's view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218500"} {"pmid": "4218503", "title": "Fluorescence-activated cell sorting of human T and B lymphocytes. I. Direct evidence that lymphocytes with a high density of membrane-bound immunoglobulin are precursors of plasmacytes.", "content": "Fluorescence-activated cell sorting of human T and B lymphocytes. I. Direct evidence that lymphocytes with a high density of membrane-bound immunoglobulin are precursors of plasmacytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218503"} {"pmid": "4218501", "title": "Cytoplasmic membrane changes in conjugating Tetrahymena.", "content": "Cytoplasmic membrane changes in conjugating Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218501"} {"pmid": "4218506", "title": "Serological testing in malaria.", "content": "Serological testing in malaria. The main purpose of this paper is to evaluate, in a critical manner, various serological tests with general emphasis on their value in the epidemiological assessment of malaria. Several tests have been employed in the past. However, the present memorandum will deal only with the methods that have been widely used recently-i.e., indirect immunofluorescence (IFA), passive haemagglutination (IHA), and gel-diffusion. The three immunoglobulins most commonly involved in these tests are IgG, IgM, and-to a lesser extent-IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218506"} {"pmid": "4218504", "title": "Macrophage migration from an agarose droplet: a micromethod for assay of delayed hypersensitivity in the mouse.", "content": "Macrophage migration from an agarose droplet: a micromethod for assay of delayed hypersensitivity in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218504"} {"pmid": "4218502", "title": "Retinal projections traced with thaw-mount autoradiography and multiple injections of tritiated precursor or precursor cocktail.", "content": "Retinal projections traced with thaw-mount autoradiography and multiple injections of tritiated precursor or precursor cocktail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218502"} {"pmid": "4218543", "title": "Distribution of plasma proteins and hyaluronic acid in synovial fluid and serum of human subjects in hydarthrosis.", "content": "Distribution of plasma proteins and hyaluronic acid in synovial fluid and serum of human subjects in hydarthrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218543"} {"pmid": "4218544", "title": "Comparison of serum vitamin B12 determination by two isotope dilution methods and by Euglena assay, with special reference to low values.", "content": "Comparison of serum vitamin B12 determination by two isotope dilution methods and by Euglena assay, with special reference to low values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218544"} {"pmid": "4218545", "title": "The use of merthiolate for TBG-blocking in the radioimmunoassay of triiodothyronine.", "content": "The use of merthiolate for TBG-blocking in the radioimmunoassay of triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218545"} {"pmid": "4218547", "title": "Letter: Comments on the article, \"Chlorinated hydrocarbons in the Sargasso Sea atmosphere and surface water.", "content": "Letter: Comments on the article, \"Chlorinated hydrocarbons in the Sargasso Sea atmosphere and surface water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218547"} {"pmid": "4218550", "title": "In vitro inhibition of succinic dehydrogenase by manganese and its reversal by chelating agents.", "content": "In vitro inhibition of succinic dehydrogenase by manganese and its reversal by chelating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218550"} {"pmid": "4218549", "title": "Relation between pituitary responsiveness to thyrotropin releasing hormone and serum thyroid hormones in hyperthyroidism.", "content": "Relation between pituitary responsiveness to thyrotropin releasing hormone and serum thyroid hormones in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218549"} {"pmid": "4218546", "title": "Effect of depletion of serum calcium by EGTA on canine pancreatic secretion induced by dopamine and by secretin.", "content": "Effect of depletion of serum calcium by EGTA on canine pancreatic secretion induced by dopamine and by secretin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218546"} {"pmid": "4218562", "title": "Test for mycoplasma on tissue culture vaccines.", "content": "Test for mycoplasma on tissue culture vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218562"} {"pmid": "4218563", "title": "Experiences in the use of biological indicators in ethylene oxide sterilization.", "content": "Experiences in the use of biological indicators in ethylene oxide sterilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218563"} {"pmid": "4218564", "title": "Microbacterium lacticum, troublemaker in blood fractions.", "content": "Microbacterium lacticum, troublemaker in blood fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218564"} {"pmid": "4218565", "title": "Application of laminar flow (clean work bench) for purifying the atmosphere.", "content": "Application of laminar flow (clean work bench) for purifying the atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218565"} {"pmid": "4218566", "title": "Comparative studies on culture media used for sterility testing.", "content": "Comparative studies on culture media used for sterility testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218566"} {"pmid": "4218567", "title": "Functionally balanced nomograms for reading the interdependence of PO2 and HbO2 in some laboratory animals.", "content": "Functionally balanced nomograms for reading the interdependence of PO2 and HbO2 in some laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218567"} {"pmid": "4218568", "title": "Mechanism of the action of some antithyroid substances: influence of methylmercaptoimidazole on the enzyme activities in the tissues of thyroidectomised guinea-pigs with suppressed secretion of the thyrotropic hormone.", "content": "Mechanism of the action of some antithyroid substances: influence of methylmercaptoimidazole on the enzyme activities in the tissues of thyroidectomised guinea-pigs with suppressed secretion of the thyrotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218568"} {"pmid": "4218569", "title": "Some monosaccharide oximes as cholinesterase reactivators following the loading of white rats with parathion.", "content": "Some monosaccharide oximes as cholinesterase reactivators following the loading of white rats with parathion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218569"} {"pmid": "4218570", "title": "The effects of some protective media during thyroid gland preservation in liquid nitrogen at--196 degrees C.", "content": "The effects of some protective media during thyroid gland preservation in liquid nitrogen at--196 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218570"} {"pmid": "4218571", "title": "An x-ray investigation of the development of the frontal sinuses in children.", "content": "An x-ray investigation of the development of the frontal sinuses in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218571"} {"pmid": "4218572", "title": "Urine excretion of vit. B12 58Co in patients with hepatic cirrhosis previously treated with therapeutic dose- of non-radioactive vit. B12.", "content": "Urine excretion of vit. B12 58Co in patients with hepatic cirrhosis previously treated with therapeutic dose- of non-radioactive vit. B12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218572"} {"pmid": "4218573", "title": "The synthesis of 113m-In-complex for the scintigraphic study of the kidneys.", "content": "The synthesis of 113m-In-complex for the scintigraphic study of the kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218573"} {"pmid": "4218574", "title": "The ectotympanic bone and origin of higher primates.", "content": "The ectotympanic bone and origin of higher primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218574"} {"pmid": "4218575", "title": "Changes in facial color associated with pregnancy in patas monkeys. (With 1 color plate).", "content": "Changes in facial color associated with pregnancy in patas monkeys. (With 1 color plate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218575"} {"pmid": "4218576", "title": "Letter: Effect of dosing technique on absorption of carbaryl.", "content": "Letter: Effect of dosing technique on absorption of carbaryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218576"} {"pmid": "4218577", "title": "The effect of polychlorinated biphenyls on rat reproduction.", "content": "The effect of polychlorinated biphenyls on rat reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218577"} {"pmid": "4218578", "title": "Complexes in plasma between light chain kappa immunoglobulins and alpha 1-antitrypsin respectively prealbumin.", "content": "Complexes in plasma between light chain kappa immunoglobulins and alpha 1-antitrypsin respectively prealbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218578"} {"pmid": "4218579", "title": "Studies on cryoprecipitation: covalent structure of a human IgG cryoglobulin and its gelation characteristics.", "content": "Studies on cryoprecipitation: covalent structure of a human IgG cryoglobulin and its gelation characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218579"} {"pmid": "4218580", "title": "A 22S cryomacroglobulin with antibody-like activity. I. Physico-chemical characterization and modification of its cryoproperties.", "content": "A 22S cryomacroglobulin with antibody-like activity. I. Physico-chemical characterization and modification of its cryoproperties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218580"} {"pmid": "4218581", "title": "Quantitation of hemoglobins by immunodiffusion: specific antibodies to hemoglobins A1, S and F.", "content": "Quantitation of hemoglobins by immunodiffusion: specific antibodies to hemoglobins A1, S and F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218581"} {"pmid": "4218582", "title": "The identification of IgE in human head hair.", "content": "The identification of IgE in human head hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218582"} {"pmid": "4218583", "title": "Carbohydrate composition and complement fixation of human monoclonal IgG.", "content": "Carbohydrate composition and complement fixation of human monoclonal IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218583"} {"pmid": "4218585", "title": "An improved method for preparation of stable antigen coupled erythrocytes for passive hemolysis.", "content": "An improved method for preparation of stable antigen coupled erythrocytes for passive hemolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218585"} {"pmid": "4218584", "title": "Chemical analyses of cryoglobulins.", "content": "Chemical analyses of cryoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218584"} {"pmid": "4218586", "title": "Rabbit immunoglobulin lambda chains: isolation and amino acid sequence of cysteine-containing peptides.", "content": "Rabbit immunoglobulin lambda chains: isolation and amino acid sequence of cysteine-containing peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218586"} {"pmid": "4218588", "title": "Immunochemical studies of human red cell membrane proteins excreted in normal urine.", "content": "Immunochemical studies of human red cell membrane proteins excreted in normal urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218588"} {"pmid": "4218587", "title": "Preferential allotypic expression of anti-hapten response in first and second generation heterozygous rabbits of al,3 allotype.", "content": "Preferential allotypic expression of anti-hapten response in first and second generation heterozygous rabbits of al,3 allotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218587"} {"pmid": "4218589", "title": "Free and bound carcinoembryonic antigen in neoplasms and in normal adult and fetal tissue.", "content": "Free and bound carcinoembryonic antigen in neoplasms and in normal adult and fetal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218589"} {"pmid": "4218591", "title": "Development of a radioimmunoassay for luteotropin releasing hormone (LRH) and thyrotropin releasing hormone (TRH).", "content": "Development of a radioimmunoassay for luteotropin releasing hormone (LRH) and thyrotropin releasing hormone (TRH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218591"} {"pmid": "4218590", "title": "The NH2-terminal amino acid sequence of a kappa and a lambda Bence-Jones cryoglobulin.", "content": "The NH2-terminal amino acid sequence of a kappa and a lambda Bence-Jones cryoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218590"} {"pmid": "4218592", "title": "The calculation of antigen concentrations in the single radial immunodiffusion.", "content": "The calculation of antigen concentrations in the single radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218592"} {"pmid": "4218593", "title": "An antiglobulin reagent labelled with colloidal gold for use in electron microscopy.", "content": "An antiglobulin reagent labelled with colloidal gold for use in electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218593"} {"pmid": "4218594", "title": "Immunoglobulin synthesis in tumors of human lymphoid origin serially transplantable in the neonatal Syrian hamster.", "content": "Immunoglobulin synthesis in tumors of human lymphoid origin serially transplantable in the neonatal Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218594"} {"pmid": "4218595", "title": "Agglutination of normal and neoplastic human cells by Concanavalin A and Ricinus communis agglutinin.", "content": "Agglutination of normal and neoplastic human cells by Concanavalin A and Ricinus communis agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218595"} {"pmid": "4218596", "title": "Lactose synthetase induction by hormones in normal and tumorous GR mouse mammary tissue.", "content": "Lactose synthetase induction by hormones in normal and tumorous GR mouse mammary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218596"} {"pmid": "4218597", "title": "Random chromosome changes following SA7 transformation of Syrian hamster cells.", "content": "Random chromosome changes following SA7 transformation of Syrian hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218597"} {"pmid": "4218598", "title": "Herpesvirus ateles: properties of an oncogenic herpesvirus isolated from circulating lymphocytes of spider monkeys (Ateles sp.).", "content": "Herpesvirus ateles: properties of an oncogenic herpesvirus isolated from circulating lymphocytes of spider monkeys (Ateles sp.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218598"} {"pmid": "4218601", "title": "Effects of sublethal x-ray doses on the number of ovarioles in Drosophila melanogaster populations.", "content": "Effects of sublethal x-ray doses on the number of ovarioles in Drosophila melanogaster populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218601"} {"pmid": "4218600", "title": "Occurrence of tubercle bacilli in urine or menstrual blood in patients at final examination before intended deletion from the dispensary register.", "content": "Occurrence of tubercle bacilli in urine or menstrual blood in patients at final examination before intended deletion from the dispensary register.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218600"} {"pmid": "4218602", "title": "Calf serum content of cell culture grown viral vaccines and possibilities for its reduction.", "content": "Calf serum content of cell culture grown viral vaccines and possibilities for its reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218602"} {"pmid": "4218603", "title": "Report of an informal meeting of manufacturers and the control laboratory on influenza vaccine. Held at the National Institute for Biological Standards and Control on Monday, 17 December 1973.", "content": "Report of an informal meeting of manufacturers and the control laboratory on influenza vaccine. Held at the National Institute for Biological Standards and Control on Monday, 17 December 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218603"} {"pmid": "4218604", "title": "Preservation of sera by means of paper discs.", "content": "Preservation of sera by means of paper discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218604"} {"pmid": "4218605", "title": "Determination of diphtheria antitoxin in guinea-pig sera by the Jensen and tissue-culture methods.", "content": "Determination of diphtheria antitoxin in guinea-pig sera by the Jensen and tissue-culture methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218605"} {"pmid": "4218606", "title": "Baseline karyologic values for primary rhesus and African green monkey cell cultures.", "content": "Baseline karyologic values for primary rhesus and African green monkey cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218606"} {"pmid": "4218608", "title": "von Recklinghausen's disease presenting as the neurofibrosarcoma of the female breast.", "content": "von Recklinghausen's disease presenting as the neurofibrosarcoma of the female breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218608"} {"pmid": "4218609", "title": "Educational planning for long-term care administration.", "content": "Educational planning for long-term care administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218609"} {"pmid": "4218610", "title": "Guest editorial: Long term care--a top health priority.", "content": "Guest editorial: Long term care--a top health priority.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218610"} {"pmid": "4218611", "title": "Editorial: The role of the administrator in the long term care facility.", "content": "Editorial: The role of the administrator in the long term care facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218611"} {"pmid": "4218612", "title": "Guest editorial: Education for the profession--an AUPHA update.", "content": "Guest editorial: Education for the profession--an AUPHA update.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218612"} {"pmid": "4218613", "title": "Evaluating the organization and management of the long term care program.", "content": "Evaluating the organization and management of the long term care program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218613"} {"pmid": "4218614", "title": "Editorial: Regulation of long term care.", "content": "Editorial: Regulation of long term care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218614"} {"pmid": "4218615", "title": "Guest editorial: PSRO review of long term care.", "content": "Guest editorial: PSRO review of long term care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218615"} {"pmid": "4218599", "title": "Autoimmune diseases and thalidomide. II. Adjuvant disease, experimental allergic encephalomyelitis and experimental allergic neuritis of the rat.", "content": "Autoimmune diseases and thalidomide. II. Adjuvant disease, experimental allergic encephalomyelitis and experimental allergic neuritis of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218599"} {"pmid": "4218616", "title": "Patient care assessment: a managerial strategy.", "content": "Patient care assessment: a managerial strategy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218616"} {"pmid": "4218619", "title": "Aleutian disease--1974.", "content": "Aleutian disease--1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218619"} {"pmid": "4218620", "title": "Acute infectious agent arthritis (IAA): a detailed comparison of proved gonococcal and other blood-borne bacterial arthritis.", "content": "Acute infectious agent arthritis (IAA): a detailed comparison of proved gonococcal and other blood-borne bacterial arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218620"} {"pmid": "4218621", "title": "Social and cultural aspects of hospitalised malnourished children in Jordan.", "content": "Social and cultural aspects of hospitalised malnourished children in Jordan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218621"} {"pmid": "4218622", "title": "Cell mediated immunity in protein-calorie malnutrition.", "content": "Cell mediated immunity in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218622"} {"pmid": "4218623", "title": "Pathological observations of feline mast cell tumor.", "content": "Pathological observations of feline mast cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218623"} {"pmid": "4218625", "title": "Mechanism of action of antitumor agents on bacteria. II. Effect of acetyl-kidamycin on nucleic acids.", "content": "Mechanism of action of antitumor agents on bacteria. II. Effect of acetyl-kidamycin on nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218625"} {"pmid": "4218617", "title": "Guest editorial: Physician services and long term care institutions.", "content": "Guest editorial: Physician services and long term care institutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218617"} {"pmid": "4218636", "title": "On the possibility of in vitro transformation of human peripheral blood lymphocytes by chemical carcinogens.", "content": "On the possibility of in vitro transformation of human peripheral blood lymphocytes by chemical carcinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218636"} {"pmid": "4218637", "title": "Disseminated herpes simplex in untreated multiple myeloma. Paradox of present concepts of immune defects.", "content": "Disseminated herpes simplex in untreated multiple myeloma. Paradox of present concepts of immune defects. A patient with disseminated herpes simplex virus infection, documented by direct immunofluorescence, and untreated multiple myeloma with abnormal immunoglobulins is presented. Reports of infections with intracellular pathogens in myeloma patients are rare, whereas pyogenic infections have been amply documented. Partly in consequence of this, the untreated disease has been thought of as a relatively pure defect in humoral immunity. Review of present knowledge suggests that cell-mediated immunity is of paramount importance in combatting and containing infection with this virus. Thus, immune defects in multiple myeloma, and its infectious complications, may be more complex than appreciated by current concepts of this disease based on previously reported cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218637"} {"pmid": "4218643", "title": "Effects of insulin and growth hormone on protein synthesis in newborn offspring of protein-energy malnourished rabbits.", "content": "Effects of insulin and growth hormone on protein synthesis in newborn offspring of protein-energy malnourished rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218643"} {"pmid": "4218644", "title": "The effects of trace elements and ethylenediaminetetraacetic acid on the survival of chicks inoculated with Salmonella gallinarum.", "content": "The effects of trace elements and ethylenediaminetetraacetic acid on the survival of chicks inoculated with Salmonella gallinarum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218644"} {"pmid": "4218645", "title": "Enzyme derivatives containing reactive groups. II. Immobilization of alpha-amylase on human erythrocytes using 5,5 dithiobis (2 nitro benzoic acid) and M-maleimidobenzoic acid adducts.", "content": "Enzyme derivatives containing reactive groups. II. Immobilization of alpha-amylase on human erythrocytes using 5,5 dithiobis (2 nitro benzoic acid) and M-maleimidobenzoic acid adducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218645"} {"pmid": "4218646", "title": "Action of 5-hydroxytryptamine, histamine and methergoline on phagocytosis.", "content": "Action of 5-hydroxytryptamine, histamine and methergoline on phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218646"} {"pmid": "4218647", "title": "Synergistic lethal action of alkylating agents and sodium pentobarbital in the mouse.", "content": "Synergistic lethal action of alkylating agents and sodium pentobarbital in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218647"} {"pmid": "4218654", "title": "Recent advances in parenteral alimentation of infants.", "content": "Recent advances in parenteral alimentation of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218654"} {"pmid": "4218658", "title": "Simultaneous insulin immunoassay in sera, heparin-, and EDTA-plasma.", "content": "Simultaneous insulin immunoassay in sera, heparin-, and EDTA-plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218658"} {"pmid": "4218660", "title": "Acid-base status in nonketotic diabetics.", "content": "Acid-base status in nonketotic diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218660"} {"pmid": "4218661", "title": "Cell agglutinating activities of some enteric bacteria and effects of various factors on bacteria-tumor cell agglutination.", "content": "Cell agglutinating activities of some enteric bacteria and effects of various factors on bacteria-tumor cell agglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218661"} {"pmid": "4218652", "title": "Anti-Trypanosoma cruzi IgM antibodies as serological evidence of recent infection.", "content": "Anti-Trypanosoma cruzi IgM antibodies as serological evidence of recent infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218652"} {"pmid": "4218664", "title": "A demonstration of the role of the renal erythropoietic factor in erythropoietin production.", "content": "A demonstration of the role of the renal erythropoietic factor in erythropoietin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218664"} {"pmid": "4218665", "title": "Letter: Effect of diethylcarbamazine on the filarial skin test.", "content": "Letter: Effect of diethylcarbamazine on the filarial skin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218665"} {"pmid": "4218666", "title": "Letter: Mebendazole--ineffective against Onchocerca volvulus.", "content": "Letter: Mebendazole--ineffective against Onchocerca volvulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218666"} {"pmid": "4218667", "title": "Incidence of sarcosporidiosis in sheep in Iran.", "content": "Incidence of sarcosporidiosis in sheep in Iran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218667"} {"pmid": "4218668", "title": "Role of Australia (Au) antigen in chronic liver disease in infancy and childhood.", "content": "Role of Australia (Au) antigen in chronic liver disease in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218668"} {"pmid": "4218663", "title": "Sulfate reabsorption by the urinary bladder of Bufo marinus.", "content": "Sulfate reabsorption by the urinary bladder of Bufo marinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218663"} {"pmid": "4218669", "title": "Foetal medicine.", "content": "Foetal medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218669"} {"pmid": "4218678", "title": "A comparative golgi sutdy of the neocortex in insectivores and rodents.", "content": "A comparative golgi sutdy of the neocortex in insectivores and rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218678"} {"pmid": "4218685", "title": "Severe neonatal jaundice. Analysis of possible associated factors in infants from Accra.", "content": "Severe neonatal jaundice. Analysis of possible associated factors in infants from Accra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218685"} {"pmid": "4218686", "title": "Clinical experience with dihydroergocristine-reserpine-clopamide combination (brinerdin) in Ghanaian hypertensives.", "content": "Clinical experience with dihydroergocristine-reserpine-clopamide combination (brinerdin) in Ghanaian hypertensives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218686"} {"pmid": "4218688", "title": "Remission of severe diabetes mellitus in a Ghanaian.", "content": "Remission of severe diabetes mellitus in a Ghanaian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218688"} {"pmid": "4218687", "title": "A simple laboratory diagnosis of meningitis: the causative organism and therapy.", "content": "A simple laboratory diagnosis of meningitis: the causative organism and therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218687"} {"pmid": "4218693", "title": "Myoglobin in homozygous beta-thalassaemia.", "content": "Myoglobin in homozygous beta-thalassaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218693"} {"pmid": "4218694", "title": "High transfusion regime in the management of reproductive wastage and maternal complications of pregnancy in thalassaemia major.", "content": "High transfusion regime in the management of reproductive wastage and maternal complications of pregnancy in thalassaemia major.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218694"} {"pmid": "4218695", "title": "Increased capillary permeability in haemophilia and afibrinogenaemia.", "content": "Increased capillary permeability in haemophilia and afibrinogenaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218695"} {"pmid": "4218696", "title": "Antiglobulin antibodies and anticomplementary factors in hepatitis b antigenaemia.", "content": "Antiglobulin antibodies and anticomplementary factors in hepatitis b antigenaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218696"} {"pmid": "4218697", "title": "Myeloma in a case of hodgkin's disease.", "content": "Myeloma in a case of hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218697"} {"pmid": "4218698", "title": "Thrombotic thrombocytopenic purpura with autoimmune pancytopenia.", "content": "Thrombotic thrombocytopenic purpura with autoimmune pancytopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218698"} {"pmid": "4218701", "title": "Distribution of lipase (EC 3.1.1.3) in the digestive system of two teleost fishes.", "content": "Distribution of lipase (EC 3.1.1.3) in the digestive system of two teleost fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218701"} {"pmid": "4218700", "title": "The localization of alkaline phosphatase activity in the rat small intestinal epithelium after fat and protein feeding.", "content": "The localization of alkaline phosphatase activity in the rat small intestinal epithelium after fat and protein feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218700"} {"pmid": "4218702", "title": "Localisation of alkaline phosphatase activity in the ovary of the percoid teleost fish Nandus.", "content": "Localisation of alkaline phosphatase activity in the ovary of the percoid teleost fish Nandus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218702"} {"pmid": "4218703", "title": "Histochemical localization of esterase and lipase in the digestive system of two teleost fishes.", "content": "Histochemical localization of esterase and lipase in the digestive system of two teleost fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218703"} {"pmid": "4218705", "title": "Location of steroid hormone production in the ovary of Trachurus mediterraneus.", "content": "Location of steroid hormone production in the ovary of Trachurus mediterraneus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218705"} {"pmid": "4218706", "title": "Repair of the post-extraction sockets in marmosets (Callithrix jacchus).", "content": "Repair of the post-extraction sockets in marmosets (Callithrix jacchus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218706"} {"pmid": "4218708", "title": "Treatment of biliary atresia.", "content": "Treatment of biliary atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218708"} {"pmid": "4218709", "title": "Surgical approach to nutritional problems.", "content": "Surgical approach to nutritional problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218709"} {"pmid": "4218710", "title": "Parrallel enzymatic changes detectable in cancer and schizophrenic patients as a possible result of environmental stimulation.", "content": "Parrallel enzymatic changes detectable in cancer and schizophrenic patients as a possible result of environmental stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218710"} {"pmid": "4218711", "title": "Certain experimentally demonstrated connections of the chief sensory trigeminal nucleus in the squirrel monkey Saimiri sciureus.", "content": "Certain experimentally demonstrated connections of the chief sensory trigeminal nucleus in the squirrel monkey Saimiri sciureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218711"} {"pmid": "4218719", "title": "Immunoglobulin biosynthesis and its control.", "content": "Immunoglobulin biosynthesis and its control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218719"} {"pmid": "4218720", "title": "Rabbit heavy chain allotypes: are they subjected to selective pressure?", "content": "Rabbit heavy chain allotypes: are they subjected to selective pressure?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218720"} {"pmid": "4218721", "title": "Choline incorporation into phospholipids by microsomal fractions from L5178Y lymphoma.", "content": "Choline incorporation into phospholipids by microsomal fractions from L5178Y lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218721"} {"pmid": "4218722", "title": "Transport of folate compounds into Lactobacillus Casei.", "content": "Transport of folate compounds into Lactobacillus Casei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218722"} {"pmid": "4218723", "title": "Changes in serotonin (5-HT) concentrations in brain tissue of rats with adjuvant-induced polyarthritis.", "content": "Changes in serotonin (5-HT) concentrations in brain tissue of rats with adjuvant-induced polyarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218723"} {"pmid": "4218724", "title": "Optimal conditions for the hydrolysis of seclazone by rat hepatic microsomes.", "content": "Optimal conditions for the hydrolysis of seclazone by rat hepatic microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218724"} {"pmid": "4218725", "title": "Effects of bacterial cardio-stimulating substance on cardiac metabolism in dogs.", "content": "Effects of bacterial cardio-stimulating substance on cardiac metabolism in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218725"} {"pmid": "4218717", "title": "Cytochemical changes in conjugants and exconjugants of Blepharisma intermedium.", "content": "Cytochemical changes in conjugants and exconjugants of Blepharisma intermedium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218717"} {"pmid": "4218753", "title": "Peribiliary portal system in the monkey liver as evidenced by the injection replica scanning electron microscope method.", "content": "Peribiliary portal system in the monkey liver as evidenced by the injection replica scanning electron microscope method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218753"} {"pmid": "4218757", "title": "Acquired diverticula of the vermiform appendix.", "content": "Acquired diverticula of the vermiform appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218757"} {"pmid": "4218758", "title": "Burns and the use of silver sulphadiazine.", "content": "Burns and the use of silver sulphadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218758"} {"pmid": "4218759", "title": "The successful conservative management of high-output entero-cutaneous fistulae.", "content": "The successful conservative management of high-output entero-cutaneous fistulae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218759"} {"pmid": "4218760", "title": "Some unusual aspects of clefts of the lip.", "content": "Some unusual aspects of clefts of the lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218760"} {"pmid": "4218763", "title": "The pathogenesis of muscular dystrophy: a review.", "content": "The pathogenesis of muscular dystrophy: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218763"} {"pmid": "4218764", "title": "Genetics of French-Canadians.", "content": "Genetics of French-Canadians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218764"} {"pmid": "4218765", "title": "Genetic marker systems in Philippine Negritos.", "content": "Genetic marker systems in Philippine Negritos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218765"} {"pmid": "4218766", "title": "Hip arthrography in the epiphyseal dysplasias.", "content": "Hip arthrography in the epiphyseal dysplasias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218766"} {"pmid": "4218767", "title": "Treatment of mucopolysaccharidoses.", "content": "Treatment of mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218767"} {"pmid": "4218769", "title": "Beta-glucuronidase deficiency (mucopolysaccharidosis type VII).", "content": "Beta-glucuronidase deficiency (mucopolysaccharidosis type VII).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218769"} {"pmid": "4218768", "title": "Comments on the plasma treatment of the mucopolysaccharidoses.", "content": "Comments on the plasma treatment of the mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218768"} {"pmid": "4218770", "title": "Histologic studies in the chondrodystrophies.", "content": "Histologic studies in the chondrodystrophies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218770"} {"pmid": "4218771", "title": "A possible etiologic mechanism for fibrodysplasia ossificans progressiva.", "content": "A possible etiologic mechanism for fibrodysplasia ossificans progressiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218771"} {"pmid": "4218772", "title": "Ultrastructure of cartilage in chondrodystrophies.", "content": "Ultrastructure of cartilage in chondrodystrophies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218772"} {"pmid": "4218773", "title": "Fine structure of skeletal dysplasia as seen in pseudoachondroplastic spondyloepiphyseal dysplasia and asphyxiating thoracic dystrophy.", "content": "Fine structure of skeletal dysplasia as seen in pseudoachondroplastic spondyloepiphyseal dysplasia and asphyxiating thoracic dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218773"} {"pmid": "4218774", "title": "Pseudoachondroplastic dysplasia: pathodynamics and management.", "content": "Pseudoachondroplastic dysplasia: pathodynamics and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218774"} {"pmid": "4218775", "title": "Spondyloepiphyseal dysplasia-unclassified type.", "content": "Spondyloepiphyseal dysplasia-unclassified type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218775"} {"pmid": "4218776", "title": "Spondyloepiphyseal dysplasia congenita.", "content": "Spondyloepiphyseal dysplasia congenita.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218776"} {"pmid": "4218777", "title": "Spondyloepiphyseal dysplasia tarda, X-linked form.", "content": "Spondyloepiphyseal dysplasia tarda, X-linked form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218777"} {"pmid": "4218778", "title": "Unclassified short stature, probably mild spondyloepiphyseal dysplasia.", "content": "Unclassified short stature, probably mild spondyloepiphyseal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218778"} {"pmid": "4218779", "title": "Distinctive spondyloepiphyseal dysplasia in father and three children.", "content": "Distinctive spondyloepiphyseal dysplasia in father and three children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218779"} {"pmid": "4218780", "title": "Unclassified short stature, possibly spondyloepiphyseal dysplasia, possibly multiple epiphyseal dysplasia, in father and daughter.", "content": "Unclassified short stature, possibly spondyloepiphyseal dysplasia, possibly multiple epiphyseal dysplasia, in father and daughter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218780"} {"pmid": "4218782", "title": "Spondylometaphyseal dysplasia (Brazilian type).", "content": "Spondylometaphyseal dysplasia (Brazilian type).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218782"} {"pmid": "4218781", "title": "Pleomorphism of hip disease in a large kinship with spondylo- and multiple epiphyseal dysplasia.", "content": "Pleomorphism of hip disease in a large kinship with spondylo- and multiple epiphyseal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218781"} {"pmid": "4218783", "title": "Simultaneous parastremmatic dwarfism and osteogenesis imperfecta.", "content": "Simultaneous parastremmatic dwarfism and osteogenesis imperfecta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218783"} {"pmid": "4218784", "title": "Mucopolysaccharidosis: possible Hurler/Scheie genetic compound (MPS I-H/S).", "content": "Mucopolysaccharidosis: possible Hurler/Scheie genetic compound (MPS I-H/S).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218784"} {"pmid": "4218785", "title": "The Morquio syndrome (MPS IV).", "content": "The Morquio syndrome (MPS IV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218785"} {"pmid": "4218786", "title": "Morquio syndrome in a woman with two normal children.", "content": "Morquio syndrome in a woman with two normal children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218786"} {"pmid": "4218787", "title": "Two brothers with nonkeratan-sulfate-excreting Morquio syndrome.", "content": "Two brothers with nonkeratan-sulfate-excreting Morquio syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218787"} {"pmid": "4218788", "title": "Mucolipidosis II (I-cell disease).", "content": "Mucolipidosis II (I-cell disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218788"} {"pmid": "4218789", "title": "Mucolipidosis, probably a new variant with joint deformity and peripheral nerve dysfunction.", "content": "Mucolipidosis, probably a new variant with joint deformity and peripheral nerve dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218789"} {"pmid": "4218790", "title": "Proximal focal femoral deficiency (familial).", "content": "Proximal focal femoral deficiency (familial).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218790"} {"pmid": "4218791", "title": "Fibrodysplasia ossificans progressiva (FOP) treated with diphosphonate.", "content": "Fibrodysplasia ossificans progressiva (FOP) treated with diphosphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218791"} {"pmid": "4218792", "title": "Blood viscosity in healthy men, measured in rhombospheroid viscometer on EDTA blood. A comparison with the cone-in-cone viscometer data and those of Copley.", "content": "Blood viscosity in healthy men, measured in rhombospheroid viscometer on EDTA blood. A comparison with the cone-in-cone viscometer data and those of Copley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218792"} {"pmid": "4218796", "title": "A scale of disability and prognosis in long-term mental illness.", "content": "A scale of disability and prognosis in long-term mental illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218796"} {"pmid": "4218797", "title": "Collateral inhibition in the sensorimotor cortex of the cat and the squirrel monkey - its role in control of neuronal discharges.", "content": "Collateral inhibition in the sensorimotor cortex of the cat and the squirrel monkey - its role in control of neuronal discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218797"} {"pmid": "4218798", "title": "Effects of ablating the striate cortex on a successive pattern discrimination:further study of the visual system in the tree shrew (Tupaia glis).", "content": "Effects of ablating the striate cortex on a successive pattern discrimination:further study of the visual system in the tree shrew (Tupaia glis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218798"} {"pmid": "4218799", "title": "Cerebral hemisphere: primary layering and inner structural interrelationships.", "content": "Cerebral hemisphere: primary layering and inner structural interrelationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218799"} {"pmid": "4218800", "title": "Concurrent measurement of left ventricular dPdtmax, isometric contractile force and cardiac loading in the intact monkey.", "content": "Concurrent measurement of left ventricular dPdtmax, isometric contractile force and cardiac loading in the intact monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218800"} {"pmid": "4218802", "title": "Possible role of cerebellar circuits in parkinsonian symptoms.", "content": "Possible role of cerebellar circuits in parkinsonian symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218802"} {"pmid": "4218803", "title": "Interpretation of hyperlipidemias.", "content": "Interpretation of hyperlipidemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218803"} {"pmid": "4218801", "title": "Nervous mechanisms involved in experimentally induced extrapyramidal disturbances.", "content": "Nervous mechanisms involved in experimentally induced extrapyramidal disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218801"} {"pmid": "4218804", "title": "Prindolol (Visken) and alprenolol (Aptin) in angina pectoris: a comparative clinical study with special reference to ergometer working capacity tests.", "content": "Prindolol (Visken) and alprenolol (Aptin) in angina pectoris: a comparative clinical study with special reference to ergometer working capacity tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218804"} {"pmid": "4218805", "title": "Triazolam: a sleep laboratory study of a new benzodiazepine hypnotic.", "content": "Triazolam: a sleep laboratory study of a new benzodiazepine hypnotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218805"} {"pmid": "4218806", "title": "A multicentric trial of a new synthetic antibacterial in urinary infections.", "content": "A multicentric trial of a new synthetic antibacterial in urinary infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218806"} {"pmid": "4218807", "title": "Sex-chromosome pairing and male fertility.", "content": "Sex-chromosome pairing and male fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218807"} {"pmid": "4218811", "title": "Toxicodynamics of aroclor 1254 in the male rat.", "content": "Toxicodynamics of aroclor 1254 in the male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218811"} {"pmid": "4218812", "title": "Cytostatic activity of chlamydocin, a rapidly inactivated cyclic tetrapeptide.", "content": "Cytostatic activity of chlamydocin, a rapidly inactivated cyclic tetrapeptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218812"} {"pmid": "4218814", "title": "The haematopoietic stem cell in Rauscher virus-induced erythroblastosis of BALB/c mice.", "content": "The haematopoietic stem cell in Rauscher virus-induced erythroblastosis of BALB/c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218814"} {"pmid": "4218813", "title": "In vitro drug selection in antineoplastic chemotherapy.", "content": "In vitro drug selection in antineoplastic chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218813"} {"pmid": "4218816", "title": "Assessment of the health and nutritional standards of infants and preschool children in high density Cairo community.", "content": "Assessment of the health and nutritional standards of infants and preschool children in high density Cairo community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218816"} {"pmid": "4218815", "title": "Early abortion in a family planning clinic.", "content": "Early abortion in a family planning clinic. The successful integration of sessions for very early abortion in the Planned Parenthood Clinic of San Francisco is described. Abortion sessions replaced 2 one- half days of contraceptive clinics per week. Flexible Karman cannulas and foot, or electrically-operated vacuum pumps were used. Routine testing for RhD antibody and gonorrhea were done at each abortion. 560 women were aborted during the year and 4 had repeat abortion. Problems encountered were 1.8% failed abortion requiring repeat suction, 1.6% bleeding heavier than a menstrual period, 3% infection in the uterus or surrounding tissues, and 1 ecotopic pregnancy. The abortion service in the Clinic was well accepted by patients, staff, the medical community, and the community at large.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218815"} {"pmid": "4218818", "title": "Fat absorption in protein-calorie malnutrition.", "content": "Fat absorption in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218818"} {"pmid": "4218817", "title": "Xylose absorption in protein-calorie malnutrition.", "content": "Xylose absorption in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218817"} {"pmid": "4218822", "title": "Effectiveness of Rh prophylaxis.", "content": "Effectiveness of Rh prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218822"} {"pmid": "4218821", "title": "HL-A phenotype and anti-RhO(D) immunization.", "content": "HL-A phenotype and anti-RhO(D) immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218821"} {"pmid": "4218824", "title": "Preventing the incompatible blood transfusion.", "content": "Preventing the incompatible blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218824"} {"pmid": "4218823", "title": "Immunization of RhO(D)-negative secundigravidae whose first pregnancy was terminated by induced abortion.", "content": "Immunization of RhO(D)-negative secundigravidae whose first pregnancy was terminated by induced abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218823"} {"pmid": "4218825", "title": "Some obvious problems of a developing country.", "content": "Some obvious problems of a developing country.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218825"} {"pmid": "4218827", "title": "Proceedings: Degradation of thyrotropin-releasing hormone (TRH) by serum and hypothalamic tissue and its inhibition by analogues of TRH.", "content": "Proceedings: Degradation of thyrotropin-releasing hormone (TRH) by serum and hypothalamic tissue and its inhibition by analogues of TRH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218827"} {"pmid": "4218828", "title": "Proceedings: Metabolic significance of the two interconvertible forms of M2-type pyruvate kinase.", "content": "Proceedings: Metabolic significance of the two interconvertible forms of M2-type pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218828"} {"pmid": "4218829", "title": "Proceedings: Fractionation of chromatin in sucrose gradients.", "content": "Proceedings: Fractionation of chromatin in sucrose gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218829"} {"pmid": "4218830", "title": "Proceedings: Immunological relatedness of human and porcine growth hormones.", "content": "Proceedings: Immunological relatedness of human and porcine growth hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218830"} {"pmid": "4218831", "title": "Proceedings: Induction of alpha-glucosidase during the cell cycle of Myxobacter Al-1.", "content": "Proceedings: Induction of alpha-glucosidase during the cell cycle of Myxobacter Al-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218831"} {"pmid": "4218832", "title": "Proceedings: The effect of glucose concentration on the interconversion of the two forms of glycogen phosphorylase and of glycogen synthase in isolated rat hepatocytes.", "content": "Proceedings: The effect of glucose concentration on the interconversion of the two forms of glycogen phosphorylase and of glycogen synthase in isolated rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218832"} {"pmid": "4218833", "title": "Proceedings: Epinephrine binding by rat liver plasma membranes. Effect of guanyl nucleotides and EDTA.", "content": "Proceedings: Epinephrine binding by rat liver plasma membranes. Effect of guanyl nucleotides and EDTA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218833"} {"pmid": "4218834", "title": "Proceedings: The defect in Maroteaux-Lamy disease (mucopolysaccharidosis VI, subtype A): deficiency of N-acetylgalactosamine-4-sulfatase.", "content": "Proceedings: The defect in Maroteaux-Lamy disease (mucopolysaccharidosis VI, subtype A): deficiency of N-acetylgalactosamine-4-sulfatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218834"} {"pmid": "4218835", "title": "Proceedings: Aspects of regulation of the pathways for D-glucose 6-phosphate, D-galactose, and L-arabinose in Pseudomonas fluorescens.", "content": "Proceedings: Aspects of regulation of the pathways for D-glucose 6-phosphate, D-galactose, and L-arabinose in Pseudomonas fluorescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218835"} {"pmid": "4218826", "title": "[Preservation of chicken and quinea-pig erthrocytes for the haemagglutination test by \"Newcastle disease virus\": electron microscopic studies].", "content": "[Preservation of chicken and quinea-pig erthrocytes for the haemagglutination test by \"Newcastle disease virus\": electron microscopic studies].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218826"} {"pmid": "4218836", "title": "Proceedings: Structural features determining the antibiotic potencies against Bacillus subtilis of the membrane active hop bitter resins.", "content": "Proceedings: Structural features determining the antibiotic potencies against Bacillus subtilis of the membrane active hop bitter resins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218836"} {"pmid": "4218837", "title": "Proceedings: The complete amino acid sequence of a rat kappa-light chain.", "content": "Proceedings: The complete amino acid sequence of a rat kappa-light chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218837"} {"pmid": "4218838", "title": "Proceedings: Inhibition of fatty acid biosynthesis with cerulenin and its effects on citrate-Mg-2 transport and macromolecular syntheses in Bacillus subtilis.", "content": "Proceedings: Inhibition of fatty acid biosynthesis with cerulenin and its effects on citrate-Mg-2 transport and macromolecular syntheses in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218838"} {"pmid": "4218840", "title": "DNA replication continued in isolated nuclei of synchronously growing Physarum polycephalum.", "content": "DNA replication continued in isolated nuclei of synchronously growing Physarum polycephalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218840"} {"pmid": "4218843", "title": "Human cyclopia with assiciated anomalies.", "content": "Human cyclopia with assiciated anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218843"} {"pmid": "4218842", "title": "Distribution of ABO and Rh blood groups among the tibetans.", "content": "Distribution of ABO and Rh blood groups among the tibetans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218842"} {"pmid": "4218845", "title": "Morphology of the primate nasopharynx.", "content": "Morphology of the primate nasopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218845"} {"pmid": "4218846", "title": "The role of cartilage in long bone growth: a reappraisal.", "content": "The role of cartilage in long bone growth: a reappraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218846"} {"pmid": "4218847", "title": "Studies on the biosynthesis of beta-lactam antibiotics. (part)I. Stereo-specific syntheses of (2RS,3S)-[4,4,4-2-H3]-, (2RS,3S)-[4-3-H]-,(RS,3R)- [4-3-H]-, and (2RS,3S)-[4-13C]-valine. Incorporation of (2RS,3S)-[4-13C]- valine into penicillin V.", "content": "Studies on the biosynthesis of beta-lactam antibiotics. (part)I. Stereo-specific syntheses of (2RS,3S)-[4,4,4-2-H3]-, (2RS,3S)-[4-3-H]-,(RS,3R)- [4-3-H]-, and (2RS,3S)-[4-13C]-valine. Incorporation of (2RS,3S)-[4-13C]- valine into penicillin V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218847"} {"pmid": "4218848", "title": "3-Hydroxyaflatoxin B1: a new metabolite of in vitro aflatoxin B1 metabolism by Vervet monkey (Cercopithecus aethiops) liver.", "content": "3-Hydroxyaflatoxin B1: a new metabolite of in vitro aflatoxin B1 metabolism by Vervet monkey (Cercopithecus aethiops) liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218848"} {"pmid": "4218849", "title": "Studies of common baldness in the stump-tailed macaque. V. Regional difference of testosterone metabolites in the hair follicles.", "content": "Studies of common baldness in the stump-tailed macaque. V. Regional difference of testosterone metabolites in the hair follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218849"} {"pmid": "4218844", "title": "The synthesis, assembly, and secretion of immunoglobulin: a biochemical and genetic approach.", "content": "The synthesis, assembly, and secretion of immunoglobulin: a biochemical and genetic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218844"} {"pmid": "4218864", "title": "Problems and pitfalls in blood grouping tests for non-parentage. IV. Qualifications of experts.", "content": "Problems and pitfalls in blood grouping tests for non-parentage. IV. Qualifications of experts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218864"} {"pmid": "4218866", "title": "Ultrastructural studies of the dying-back process. II. The sequestration and removal by Schwann cells and oligodendrocytes of organelles from normal and diseases axons.", "content": "Ultrastructural studies of the dying-back process. II. The sequestration and removal by Schwann cells and oligodendrocytes of organelles from normal and diseases axons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218866"} {"pmid": "4218867", "title": "A histological comparison of the giant cells in the central giant cell granuloma of the jaws and the giant cell tumor of long bone.", "content": "A histological comparison of the giant cells in the central giant cell granuloma of the jaws and the giant cell tumor of long bone. A histological comparison has been made of the giant cells in 10 cases which had been diagnosed as central giant cell granuloma of the jaws and 10 cases diagnosed as giant cell tumor of long bone. The numbers of nuclei in each of 50 giant cells were counted in the 20 lesions. The giant cells were measured in order to compare their sizes in the respective lesions. It was found that the giant cells of the jaw lesions contained significantly fewer nuclei than those of the lesions in other bones. Secondly it was found that cells in the lesions of long bone have significantly larger dimensions than those in the jaw lesions. There was, however, an area of overlap. It was concluded that these data supported the view that giant cell tumor and giant cell granuloma are distinct entities. Some giant cell lesions of long bones are, however, morphologically indistinguishable from lesions of the jaws; and conversely giant cell lesions of the jaws are indistinguishable from some giant cell lesions of the long bones. It seems possible, therefore, that some jaw lesions are giant cell tumors and that some giant cell lesions outside the jaws are giant cell granulomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218867"} {"pmid": "4218868", "title": "Tissue reactions to two fissure sealant resina.", "content": "Tissue reactions to two fissure sealant resina. Specimens of polymerized and unpolymerized Nuva-Seal and Alpha-Seal were implanted subcutaneously on polythene rods. Polymerized specimens caused only slightly greater reaction than controls over intervals of from 2 days to 1 year. Unpolymerized specimens caused necrosis, marked inflammatory cell infiltration and granulation tissue formation for up to 1 week but were similar to the controls at 1 year. No reaction to unpolymerized resin painted on the oral mucosa was observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218868"} {"pmid": "4218869", "title": "Leukocyte mediated cytotoxicity of chemically induced rat salivary gland neoplasms.", "content": "Leukocyte mediated cytotoxicity of chemically induced rat salivary gland neoplasms. Chemically induced tumors of the rat submaxillary glands were tested for the presence of tumor antigens by in vitro leukocyte mediated cytotoxicity assays. Since it has been reported that the saliva of humans with oral cancer contains markedly elevated levels of secretory antibody, the rats' saliva specimens were also tested for blocking and/or potentiating \"antibody\" activity. The results indicate that saliva from tumor-bearing animals potentiated tumor cell killing if either the tumor cells or leukocytes were pretreated. The effect was much more marked when tumor cells were pretreated. Furthermore, the addition of saliva to tumor cells imparted an immunologic cross reactivity which was not present with untreated tumor cells. Control saliva occasionally produced a similar effect, but not as consistently or with the potency of saliva from tumor-bearing animals. Heat inactivation did not abrogate this potentiation. It is inferred that this may indicate a new system of immunologic surveillance, i.e. arming or potentiation of leukocytes by soluble tumor antigens in glandular secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218869"} {"pmid": "4218870", "title": "In vivo calcification of implanted bone cells.", "content": "In vivo calcification of implanted bone cells. Bone cells raised in cell culture from the osteogenic cells of newborn rat calvaria were reimplanted in the same species of animals from which the cells were derived. The cells were sealed in Teflon rings containing Millipore filters over both ends. Evidence of calcification occurred inside the implanted ring chambers at 118 and 279 days following implantation in vivo. The calcified matrix produced by the cells had a pattern reminiscent of membranous bone production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218870"} {"pmid": "4218871", "title": "Pharmacology and physiology of stereotyped behavior.", "content": "Pharmacology and physiology of stereotyped behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218871"} {"pmid": "4218873", "title": "Localization of the noradrenergic nervous system in human brain.", "content": "Localization of the noradrenergic nervous system in human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218873"} {"pmid": "4218874", "title": "Microbiological studies in submarines. Ecology of Meningococci in symptomless carriers.", "content": "Microbiological studies in submarines. Ecology of Meningococci in symptomless carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218874"} {"pmid": "4218872", "title": "Dopamine and the pharmacology of schizophrenia: the state of the evidence.", "content": "Dopamine and the pharmacology of schizophrenia: the state of the evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218872"} {"pmid": "4218875", "title": "Multiple ureteral diverticula.", "content": "Multiple ureteral diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218875"} {"pmid": "4218877", "title": "Biochemical characterization of the golgi complex of mammalian cells.", "content": "Biochemical characterization of the golgi complex of mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218877"} {"pmid": "4218878", "title": "Binding properties of the plant photoreceptor phytochrome to membranes.", "content": "Binding properties of the plant photoreceptor phytochrome to membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218878"} {"pmid": "4218879", "title": "Human aortic laceration secondary to impact.", "content": "Human aortic laceration secondary to impact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218879"} {"pmid": "4218895", "title": "Use of sensory recombination and somatosensory deafferentation techniques in the investigation of sensory-motor integration.", "content": "Use of sensory recombination and somatosensory deafferentation techniques in the investigation of sensory-motor integration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218895"} {"pmid": "4218894", "title": "Tyrosinase activity and isozymes in B-16 mouse melanomas.", "content": "Tyrosinase activity and isozymes in B-16 mouse melanomas. B-16 melanomas grown for 13 and 22 days after transplantation in mice were utilized in studies of subcellular distribution of tyrosinase activity and tyrosinase isozyme patterns. The tyrosinase activity utilizing L-tyrosine-14-C was higher in the younger than in the older melanomas. The percent of total activity distributed in the 144,000 g supernatant was 38% for the former and 46% for the latter. Both melanomas had higher percentage of activity confined in the pellet obtained by centrifuging the crude homogenate at 600 g. The digestion of P 600 g pellet by lipase liberated tyrosinase activity which was two fold of the activity originally counted in the pellet. Five isozymes wereobserved in the soluble tyrosinase and two in the solubilized tyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218894"} {"pmid": "4218896", "title": "A study of the distribution of polychlorinated biphenyls in the aquatic environment.", "content": "A study of the distribution of polychlorinated biphenyls in the aquatic environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218896"} {"pmid": "4218897", "title": "Analysis of gentamicin in plasma: a comparative study of four methods.", "content": "Analysis of gentamicin in plasma: a comparative study of four methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218897"} {"pmid": "4218899", "title": "Oral glucose effect on glycogen synthetase and phosphorylase in heart. Muscle and liver.", "content": "Oral glucose effect on glycogen synthetase and phosphorylase in heart. Muscle and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218899"} {"pmid": "4218898", "title": "Photosynthetic nitrogen fixation by blue-green algae.", "content": "Photosynthetic nitrogen fixation by blue-green algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218898"} {"pmid": "4218909", "title": "Clinical picture and management of testicular tumours.", "content": "Clinical picture and management of testicular tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218909"} {"pmid": "4218900", "title": "Profile of American health, 1973.", "content": "Profile of American health, 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218900"} {"pmid": "4218902", "title": "Use of contraceptive services in periods of receipt and nonreceipt of AFDC.", "content": "Use of contraceptive services in periods of receipt and nonreceipt of AFDC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218902"} {"pmid": "4218913", "title": "Mutual relations of dorsal and ventral hippocampus with the hypothalamus. I. Hippocampo-hypothalamic projections.", "content": "Mutual relations of dorsal and ventral hippocampus with the hypothalamus. I. Hippocampo-hypothalamic projections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218913"} {"pmid": "4218901", "title": "Health and healing practices among five ethnic groups in Miami, Florida.", "content": "Health and healing practices among five ethnic groups in Miami, Florida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218901"} {"pmid": "4218904", "title": "Home nursing care program on an Indian reservation.", "content": "Home nursing care program on an Indian reservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218904"} {"pmid": "4218916", "title": "An automated Rose Bengal agglutination test using the ADAM system.", "content": "An automated Rose Bengal agglutination test using the ADAM system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218916"} {"pmid": "4218915", "title": "Ocular melanin and the adrenergic innervation to the eye.", "content": "Ocular melanin and the adrenergic innervation to the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218915"} {"pmid": "4218903", "title": "Role of lay midwifery in maternity care in a large metropolitan area.", "content": "Role of lay midwifery in maternity care in a large metropolitan area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218903"} {"pmid": "4218905", "title": "Survival potential and quality of care among free clinics.", "content": "Survival potential and quality of care among free clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218905"} {"pmid": "4218907", "title": "The status of prison health care. A review of the literature.", "content": "The status of prison health care. A review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218907"} {"pmid": "4218908", "title": "The Public Health Conference on Records and Statistics meeting jointly with The American Association for Vital Records and Public Health Statistics. Highlights of the 15th national meeting.", "content": "The Public Health Conference on Records and Statistics meeting jointly with The American Association for Vital Records and Public Health Statistics. Highlights of the 15th national meeting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218908"} {"pmid": "4218906", "title": "Outcomes of methadone treatment of 300 innercity addicts.", "content": "Outcomes of methadone treatment of 300 innercity addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218906"} {"pmid": "4218928", "title": "Phylogeny, hologeny and coenogeny, basic concepts of environmental biology.", "content": "Phylogeny, hologeny and coenogeny, basic concepts of environmental biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218928"} {"pmid": "4218929", "title": "Kinetics and other characteristics of diamine oxidase of pea seedlings.", "content": "Kinetics and other characteristics of diamine oxidase of pea seedlings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218929"} {"pmid": "4218930", "title": "Experimental particle radiation therapy in animal neoplasia. II. Alpha particles versus protons.", "content": "Experimental particle radiation therapy in animal neoplasia. II. Alpha particles versus protons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218930"} {"pmid": "4218932", "title": "Immunoelectrophoretic determination of two IgM paraprotein variants.", "content": "Immunoelectrophoretic determination of two IgM paraprotein variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218932"} {"pmid": "4218936", "title": "Analysis of immunofluorescent preparations based on isolation on DEAE column.", "content": "Analysis of immunofluorescent preparations based on isolation on DEAE column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218936"} {"pmid": "4218937", "title": "Purification of anti-tetanus human IgG by immunoadsorption.", "content": "Purification of anti-tetanus human IgG by immunoadsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218937"} {"pmid": "4218938", "title": "Isolation of purified IgA and IgM as by-products of ethanol fractionation.", "content": "Isolation of purified IgA and IgM as by-products of ethanol fractionation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218938"} {"pmid": "4218939", "title": "The demonstration of the sensitizing effect of the residual animal serum content of vaccines.", "content": "The demonstration of the sensitizing effect of the residual animal serum content of vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218939"} {"pmid": "4218941", "title": "Relation of beta-lactamase activity and cellular location to resistance of Enterobacter to penicillins and cephalosporins.", "content": "Relation of beta-lactamase activity and cellular location to resistance of Enterobacter to penicillins and cephalosporins. The Enterobacter species E. aerogenes, E. cloacae, and E. hafnia were examined for resistance to penicillin and cephalosporin derivatives. All were resistant to benzyl penicillin, ampicillin, 6 [d(-)alpha-amino-p-hydroxyphenylacetamido] penicillanic acid, cephaloridine, cephalothin, and cephalexin. A significant number were sensitive to carbenicillin and 6 [d(-)alpha-carboxy-3-thienylacetamido] penicillanic acid. No differences among the three species were noted. The beta-lactamase activity was cell-bound, and was not released by osmotic shock, toluene treatment, or diphenylamine treatment. It was rarely released into the growth medium. The beta-lactamase activity was primarily directed against cephalosporin derivatives. Synthesis of beta-lactamase was chromosomally mediated. Resistance to ampicillin seemed to be partly related to entry of the molecule into the bacteria since exposure to ethylenediaminetetraacetate lowered the minimal inhibitory concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218941"} {"pmid": "4218942", "title": "Purification and characteristics of pyocin B39 II. Physical and chemical properties.", "content": "Purification and characteristics of pyocin B39 II. Physical and chemical properties. A purified preparation of pyocin B39 was shown to be homogeneous by disc electrophoresis and ultracentrifugation. Pyocin B39 is an antibacterial agent, protein in nature, and is capable of inhibiting the growth of susceptible cells. It caused a susceptible strain of Pseudomonas aeruginosa to release ultraviolet-absorbing material. Pyocin B39 appears to be a protein with a high molecular weight; its sedimentation coefficient is 32.8S. It was destroyed by 7 m urea but was resistant to attack by proteolytic enzymes, such as pepsin and trypsin. From its sedimentation coefficient, a molecular weight of about 2 x 10(6) was calculated. An electron photomicrograph of pyocin B39 revealed it as a rodlike particle, 7.50 pm long and 1.08 pm wide, with striations running at nearly right angles to the axes of the particle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218942"} {"pmid": "4218943", "title": "Antagonistic effect of calcium in serum on the activity of tobramycin against Pseudomonas.", "content": "Antagonistic effect of calcium in serum on the activity of tobramycin against Pseudomonas. Physiological concentrations of calcium in serum antagonize the activities of colistin, polymyxin B, and gentamicin against Pseudomonas aeruginosa. Studies were carried out to determine whether tobramycin, a new aminoglycoside antibiotic, is also antagonized by calcium. The activity of tobramycin in vitro was shown to be antagonized by human serum and by physiological concentrations of calcium. The addition of human serum in broth-dilution tests produced a fourfold rise in the minimal inhibitory concentrations of tobramycin for five strains of Pseudomonas. In disc diffusion tests, the addition of calcium to the agar significantly decreased the size of inhibition zones, and the addition of a chelating agent to the agar increased the zone sizes. In a limited comparative study, tobramycin and gentamicin were tested against both light and heavy bacterial inocula of two strains of Pseudomonas. Tobramycin appeared to be antagonized less by serum than was gentamicin at equal antibiotic concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218943"} {"pmid": "4218944", "title": "Enhanced toxicity for mice of vincristine and other chemotherapeutic agents with Salmonella typhosa endotoxin and Pseudomonas aeruginosa.", "content": "Enhanced toxicity for mice of vincristine and other chemotherapeutic agents with Salmonella typhosa endotoxin and Pseudomonas aeruginosa. The toxicity of Salmonella typhosa 0901 W endotoxin for BALB/c mice was potentiated by the administration of 375 mg of cyclophosphamide per kg, 16 mg of daunomycin per kg, 80 mg of methotrexate per kg, 8 mg of pactamycin per kg, 20 mg of polyinosinic-polycytidylic acid per kg, 1,000 mg of procarbazine per kg, and 1 or 4 mg of vincristine per kg. l-Asparaginase (20,000 units per kg) failed to potentiate endotoxin. Sedation following administration of 45 mg of pentobarbital per kg was prolonged in mice that had received 20,000 units of l-asparaginase per kg, 4 mg of daunomycin per kg, 120 mg of methotrexate per kg, 8 mg of pactamycin per kg, 10 mg of polyinosinic-polycytidylic acid per kg, 500 mg of procarbazine per kg, 2 mg of vincristine per kg, 2 mg of endotoxin per kg, or multiple doses of endotoxin. Mice pretreated with multiple endotoxin doses experienced a significant reduction in their lethal responses due to vincristine-endotoxin combinations; however, endotoxin-pretreated mice were more susceptible to vincristine alone than were normal mice. Simultaneous administration of 1 or 2 mg of vincristine per kg and 1 mg of endotoxin per kg produced greater lethality than sequential regimens. Pretreatment of mice with 65 mg of phenobarbital per kg on 4 consecutive days protected against vincristine-endotoxin combinations. Liver homogenates prepared from mice exposed previously to vincristine were capable of inactivating endotoxin. Vincristine lethality was increased by simultaneous administration of heat-killed cells of Pseudomonas aeruginosa isolated from mouse feces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218944"} {"pmid": "4218945", "title": "Effect of ethylenediaminetetraacetic acid and related chelating agents on whole cells of gram-negative bacteria.", "content": "Effect of ethylenediaminetetraacetic acid and related chelating agents on whole cells of gram-negative bacteria. The effects of ethylenediaminetetraacetic acid and of four other chelating agents on seven strains of gram-negative bacteria are described. Changes in viability, cell lysis, and release of intracellular materials from suspensions in various buffers, pH 7.8 or 9.2, were observed. Cyclohexane-1,2-diaminotetraacetic acid was the most toxic compound, whereas iminodiacetic acid and nitrilotriacetic acid had little bactericidal activity. The activity of the five drugs appeared to be related to their chelating ability. Of the bacterial strains used, Pseudomonas aeruginosa NCTC 1999 and NCTC 6750 were the most susceptible, and Klebsiella aerogenes K1 was the most resistant. In contrast, the two strains of P. aeruginosa were the most resistant to the nonchelating antibacterial agents cetrimide, chlorhexidine, and benzalkonium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218945"} {"pmid": "4218946", "title": "The aetiology, diagnosis and treatment of amoebic disease.", "content": "The aetiology, diagnosis and treatment of amoebic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218946"} {"pmid": "4218947", "title": "The effect of serotonin and prostaglandins on internal and external carotid blood-flow measured simultaneously in the monkey.", "content": "The effect of serotonin and prostaglandins on internal and external carotid blood-flow measured simultaneously in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218947"} {"pmid": "4218951", "title": "Functional and morphological observations on the effect of cyclophosphamide on the immune response of the chicken.", "content": "Functional and morphological observations on the effect of cyclophosphamide on the immune response of the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218951"} {"pmid": "4218952", "title": "Origin of the various immunoglobulins in lymph from the popliteal lymph node of sheep before and after antigenic stimulation.", "content": "Origin of the various immunoglobulins in lymph from the popliteal lymph node of sheep before and after antigenic stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218952"} {"pmid": "4218953", "title": "Prothrombin isolation and assay.", "content": "Prothrombin isolation and assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218953"} {"pmid": "4218955", "title": "Proteolysis of rabbit immunoglobulin M by papain.", "content": "Proteolysis of rabbit immunoglobulin M by papain. 1. Digestion of rabbit immunoglobulin M (IgM) by papain for 5h, in the absence of reducing agent, gives Fabmu and Fc(5)mu fragments in high yield. Shorter periods give fragment Fc(5)mu with one or more Fabmu fragments still attached. 2. Reducing agent in the absence of a denaturant cleaves rabbit IgM into half-subunits, each containing one mu chain and one light chain. Digestion by papain in the presence of such a reducing agent destroys the Fcmu domains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218955"} {"pmid": "4218954", "title": "Membrane-bound DD-carboxypeptidases from Bacillus megaterium KM general properties, substrate specificity and sensitivity to penicillins, cephalosporins and peptide inhibitors of the activity at pH5.", "content": "Membrane-bound DD-carboxypeptidases from Bacillus megaterium KM general properties, substrate specificity and sensitivity to penicillins, cephalosporins and peptide inhibitors of the activity at pH5. 1. The membrane from Bacillus megaterium KM contained a dd-carboxypeptidase with optimum activity under the following conditions: pH5.2, bivalent cation, 3mm; ionic strength, 40mm; temperature, 35 degrees C. It was inactivated by treatment with p-chloromercuribenzoate but was fairly insensitive to 2-mercaptoethanol. 2. The enzyme was inhibited by penicillins and cephalosporins. The inhibition of this enzyme was partially reversed on dialysis but 0.2m-2-mercaptoethanol could neither prevent nor reverse the inhibition. 3. The enzyme was extremely sensitive to changes in the configuration and size of the side chain of the C-terminal dipeptide of the substrate. An aliphatic side chain of a well-defined length and polarity was required in the residue that precedes the C-terminal dipeptide. 4. The enzyme was inhibited by a wide range of analogues of the peptidic portion of the natural substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218954"} {"pmid": "4218956", "title": "Kinetic studies on the effect of uridine diphosphate galactose and manganous ions on the reaction between lactose synthetase A protein from human milk and p-hydroxymercuribenzoate.", "content": "Kinetic studies on the effect of uridine diphosphate galactose and manganous ions on the reaction between lactose synthetase A protein from human milk and p-hydroxymercuribenzoate. The inhibition of lactose synthetase A protein by p-hydroxymercuribenzoate at pH7.5 and 25 degrees C, which involves the reaction of one molecule of inhibitor with each molecule of enzyme, was decreased in rate by UDP-galactose, especially in the presence of Mn(2+). Pseudo-first-order rate constants for the reaction between 0.1mm-p-hydroxymercuribenzoate and free enzyme, the enzyme-UDP-galactose complex and the enzyme-Mn(2+)-UDP-galactose complex were 4.4x10(-2), 1.9x10(-2) and 0.3x10(-2)min(-1) respectively. The results also indicated that dissociation constants for UDP-galactose in the enzyme-UDP-galactose and enzyme-Mn(2+)-UDP-galactose complexes were 313 and 16mum respectively, the latter value being similar to the K(m) for UDP-galactose in the lactose synthetase reaction. The protective effect of UDP-galactose and the role of Mn(2+) ions in lactose synthetase are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218956"} {"pmid": "4218957", "title": "Biological, proton-magnetic-resonance- and ultraviolet-spectroscopic evidence for a molecular complex of actinomycin D and 10,11-dihydro-3H-naphth (1,2-g)indazol-7-ol.", "content": "Biological, proton-magnetic-resonance- and ultraviolet-spectroscopic evidence for a molecular complex of actinomycin D and 10,11-dihydro-3H-naphth (1,2-g)indazol-7-ol. A proton-magnetic-resonance study of the complex formed between actinomycin D and 10,11-dihydro-3H-naphth[1,2-g]indazol-7-ol strongly suggests that the indazole lies above the phenoxazine ring of actinomycin D. The complex can be destroyed by addition of dimethyl sulphoxide or dimethylformamide. The actinomycin D-indazole complex inhibits growth of Pseudomonas fluorescens and raises the thermal denaturation response of DNA. These data support the hypothesis that a molecular complex is formed which readily inhibits cell growth and interacts with DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218957"} {"pmid": "4218958", "title": "Inhibition by progesterone of the lactogenic effect of prolactin in the pseudopregnant rabbit.", "content": "Inhibition by progesterone of the lactogenic effect of prolactin in the pseudopregnant rabbit. The effects of progesterone on lactose synthesis activity and changes in mammary gland cells were studied in pseudopregnant rabbits simultaneously treated with prolactin. The injection of progesterone alone on Days 15 and 17 of pseudopregnancy decreased the activity of lactose synthetase (LSA) and galactosyl transferase (GTA), while the administration of prolactin for 2-4 days increased their activities. Th e simultaneous administration of progesterone and prolactin decreased the increase in LSA observed with prolactin alone by 70% on the 4th day of treatment, and decreased GTA by 30%. Progesterone completely suppressed the polyribosome profile and the ratio of endoplasmic reticulum bound polyribosomes to free polyribosomes induced by prolactin. The increase in RNA content in the mammary gland induced by prolactin was also suppressed by progesterone. The results suggest that progesterone inhibits the lactogenic action of prolactin without interfe ring with its mammogenic role.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218958"} {"pmid": "4218959", "title": "Soluble neutral and acid maltases in the suckling-rat intestine. The effect of cortisol and development.", "content": "Soluble neutral and acid maltases in the suckling-rat intestine. The effect of cortisol and development. The 100000g supernatants from 13-day-old suckling-rat intestinal homogenates contained 43.5% of the total intestinal maltase activity, compared with 7.1% in weaned adult rats aged 40 days. The soluble maltase activity was separated on Sepharose 4B into two quantitatively equal fractions at pH6.0, one containing a maltase with a neutral pH optimum and the other a maltase with an acid pH optimum. The neutral maltase was shown to be a maltase-glucoamylase identical with membrane-bound maltase-glucoamylase in molecular weight, heat-sensitivity, substrate specificity, K(m) for maltose and K(i) for Tris. The soluble enzyme was induced by cortisol, but the ratio of the soluble to bound enzyme fell during induction. Solubility of the neutral maltase was not accounted for by the action of endogenous proteinases under the preparative conditions used. It is postulated that the soluble neutral maltase is a membrane-dissociated form of the bound enzyme and that the relationship between these two forms is modulated by cortisol. The acid maltase generally resembled acid maltase of liver, muscle and kidney. It was shown to be a maltase-glucoamylase with optimal activity at pH3.0, and molecular weight of 136000 by density-gradient centrifugation. At pH3.0 its K(m) for maltose was 1.5mm. It was inhibited by turanose (K(i)=7.5mm) and Tris (K(i)=5.5mm) but not by p-chloromercuribenzoate or EDTA. Some 55% of its activity was destroyed by heating at 50 degrees C for 10min. The acid maltase closely resembled beta-glucuronidase and acid beta-galactosidase in its distribution in the intestine, response to tissue homogenization in various media, and decrease in activity with cortisol treatment and weaning, indicating that it was a typical lysosomal enzyme concentrated in the ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218959"} {"pmid": "4218960", "title": "Water-soluble metabolites of p-nitrophenol and 1-naphthyl N-methylcarbamate in flies and grass grubs. Formation of glucose phosphate and phosphate conjugates.", "content": "Water-soluble metabolites of p-nitrophenol and 1-naphthyl N-methylcarbamate in flies and grass grubs. Formation of glucose phosphate and phosphate conjugates. Metabolites isolated from houseflies dosed with 1-napththol or p-nitrophenol were identified as the phosphate and glucose phosphate conjugates of these phenols by titrations, hydrolysis, ionophoresis, i.r. spectra and mixed melting point. [(3)H]Carbaryl (1-naphthyl N-methylcarbamate) was metabolized by houseflies, blowflies and grass grubs to water-soluble metabolites which had chromatographic and ionophoretic behaviour similar to those of the conjugates of 1-naphthol with glucose, sulphate, phosphate and glucose 6-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218960"} {"pmid": "4218961", "title": "Protein synthesis and breakdown in the mother-cell and forespore compartments during spore morphogenesis in Bacillus megaterium.", "content": "Protein synthesis and breakdown in the mother-cell and forespore compartments during spore morphogenesis in Bacillus megaterium. Recently developed techniques for isolating forespores from bacilli at all stages of spore morphogenesis have been exploited to investigate the contribution of each of the two compartments of the sporulating cell to the overall pattern of protein synthesis and degradation during sporulation in Bacillus megaterium. These studies have shown: (1) that protein synthesis continues in both compartments throughout spore morphogenesis; (2) that the degradation of proteins made at all times during vegetative growth and sporulation is confined to the mother-cell compartment; (3) that proteins synthesized in the mother-cell compartment during sporulation are subsequently degraded more rapidly than proteins synthesized during vegetative growth. This rate of degradation increases the later the proteins are synthesized in the sporulation sequence. Mature spores were disrupted, and the percentage of the total protein in soluble and particulate fractions was determined. Pulse-labelling experiments were performed to investigate the extent to which the proteins of these two fractions are newly synthesized during sporulation. These data were used to calculate the extent of capture of vegetative cell protein at the time of formation of the forespore septum. The value obtained is consistent with evidence from electron micrographs and supports a model for the origin of spore protein in which there is no protein turnover in the developing forespore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218961"} {"pmid": "4218963", "title": "The accumulation of malachite green stainable phospholipid in rabbit spermatozoa during maturation in the epididymis, and its possible role in capacitation.", "content": "The accumulation of malachite green stainable phospholipid in rabbit spermatozoa during maturation in the epididymis, and its possible role in capacitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218963"} {"pmid": "4218965", "title": "Mass spectrometry of the methyl esthers of isomeric hydroxychlorobiphenyls--potential metabolites of chlorobiphenyls.", "content": "Mass spectrometry of the methyl esthers of isomeric hydroxychlorobiphenyls--potential metabolites of chlorobiphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218965"} {"pmid": "4218964", "title": "The characterization of a malachite green stainable, glutaraldehyde extractable phospholipid in rabbit spermatozoa.", "content": "The characterization of a malachite green stainable, glutaraldehyde extractable phospholipid in rabbit spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218964"} {"pmid": "4218967", "title": "A simple double immunodiffusion test for typing influenza viruses.", "content": "A simple double immunodiffusion test for typing influenza viruses. The identification of influenza virus type has traditionally been based on the characterization of internal nucleoprotein (NP) antigens by the complement fixation (CF) test. Because this test is complex and time-consuming, it is used only infrequently. In this report we describe a double immunodiffusion (DID) test, which is proposed as a replacement for the CF test for the typing of influenza viruses. The DID test is simple and requires only the allantoic fluid content of a single infected embryonated egg. Virus from the infected fluid is precipitated with mild acid and disrupted by detergent. Anti-NP or anti-matrix protein (MP) antibody is equally effective in most instances for typing influenza isolates by this test. The latter is preferred, however, since it seemed to be slightly more sensitive than anti-NP antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218967"} {"pmid": "4218968", "title": "Quantitative measurement of precipitating antibodies and standardization of Streptococcus group B antisera by the reverse radial immunodiffusion technique.", "content": "Quantitative measurement of precipitating antibodies and standardization of Streptococcus group B antisera by the reverse radial immunodiffusion technique. A comparative study was made of the reverse radial immunodiffusion (RRID) technique and the quantitative precipitin test for determining the amount of precipitable antibodies present in streptococcus group B antisera. The coefficient of correlation between the 2 tests was 0.963 when a purified carbohydrate antigen was used. The results of this study show that: (1) a group B antiserum should contain at least 3 mg of precipitable antibodies per ml to ensure that it will react with acid extracts of group B diagnostic cultures; and (2) the RRID technique is an accurate and simple procedure for determining the amount of precipitable antibody present in an antiserum, and it could be used for the standardization of these diagnostic reagents. A method for preparing the group B carbohydrate antigen used in the RRID and quantitative precipitin tests is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218968"} {"pmid": "4218969", "title": "Prevalence of nonspecific tuberculin sensitivity in certain parts of India.", "content": "Prevalence of nonspecific tuberculin sensitivity in certain parts of India. A survey was carried out in certain parts of India to determine the prevalence of nonspecific tuberculin sensitivity. In the temperate zone, villages situated 1 200 m or more above mean sea level showed a markedly lower prevalence than villages in the plains did. In the tropical zone, the prevalence of nonspecific sensitivity was high. The prevalence of infection due to Mycobacterium tuberculosis was much lower than that of nonspecific sensitivity and the rates did not vary greatly in the areas surveyed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218969"} {"pmid": "4218985", "title": "Squamous metaplasia and respiratory tumors induced by intratracheal installations of 7, 12-dimethylbenz(a)-anthracene in Syrain golden hamsters.", "content": "Squamous metaplasia and respiratory tumors induced by intratracheal installations of 7, 12-dimethylbenz(a)-anthracene in Syrain golden hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218985"} {"pmid": "4218986", "title": "A new pharmacological method of host conditioning in order to facilitate in vivo growth of fibroblast-like cells cultivated in vitro.", "content": "A new pharmacological method of host conditioning in order to facilitate in vivo growth of fibroblast-like cells cultivated in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218986"} {"pmid": "4218987", "title": "Observations on the organization of the interstitial tissue of the testis and on the occluding cell junctions in the seminiferous epithelium.", "content": "Observations on the organization of the interstitial tissue of the testis and on the occluding cell junctions in the seminiferous epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218987"} {"pmid": "4218988", "title": "Prostaglandins and steroidogenesis.", "content": "Prostaglandins and steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218988"} {"pmid": "4218990", "title": "Blood group and HL-A specific substances in immune globulin and albumin preparations of human placental origin.", "content": "Blood group and HL-A specific substances in immune globulin and albumin preparations of human placental origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218990"} {"pmid": "4218992", "title": "Freeze-dried virus antigen containing cells and FITC-conjugated immune sera for virus diagnostic purposes.", "content": "Freeze-dried virus antigen containing cells and FITC-conjugated immune sera for virus diagnostic purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218992"} {"pmid": "4218995", "title": "Concentration of normal immunoglobulins in human sera.", "content": "Concentration of normal immunoglobulins in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218995"} {"pmid": "4218996", "title": "Isolation and control of human IgA and IgM preparations.", "content": "Isolation and control of human IgA and IgM preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218996"} {"pmid": "4218998", "title": "[Pathogenesis of aplastic anemia].", "content": "[Pathogenesis of aplastic anemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218998"} {"pmid": "4219000", "title": "Interaction of concanavalin A with normal and leukemic lymphocytes: binding and agglutination.", "content": "Interaction of concanavalin A with normal and leukemic lymphocytes: binding and agglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219000"} {"pmid": "4218999", "title": "Studies on double-stranded RNA synthesized in acute leukemia blast cells.", "content": "Studies on double-stranded RNA synthesized in acute leukemia blast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4218999"} {"pmid": "4219002", "title": "Congenital dyserythropoietic anemia (CDA), type I. Light and electron microscopy, erythroblastic proliferation, erythrokinetic and cytogenetic studies in one case.", "content": "Congenital dyserythropoietic anemia (CDA), type I. Light and electron microscopy, erythroblastic proliferation, erythrokinetic and cytogenetic studies in one case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219002"} {"pmid": "4219001", "title": "Splenectomy in early chronic myeloid leukaemia: preliminary report on 37 cases.", "content": "Splenectomy in early chronic myeloid leukaemia: preliminary report on 37 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219001"} {"pmid": "4219003", "title": "Factor-XIII subunits-A and -S in congenital deficiency and in acute myeloblastic leukemia.", "content": "Factor-XIII subunits-A and -S in congenital deficiency and in acute myeloblastic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219003"} {"pmid": "4219004", "title": "Virus-like particles in chronic lymphatic leukemia: ultrastructural findings.", "content": "Virus-like particles in chronic lymphatic leukemia: ultrastructural findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219004"} {"pmid": "4219006", "title": "A hematologist's appraisal of the problem cerebral lymphomas in transplanted patients. A speculative review.", "content": "A hematologist's appraisal of the problem cerebral lymphomas in transplanted patients. A speculative review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219006"} {"pmid": "4219008", "title": "[Frederick Stohlman Jr. 1926-1974].", "content": "[Frederick Stohlman Jr. 1926-1974].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219008"} {"pmid": "4219007", "title": "Hemopoietic microenvironment in acute leukemia.", "content": "Hemopoietic microenvironment in acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219007"} {"pmid": "4219009", "title": "Conditions for purification of anti-Brucella antibodies by immunoadsorption and elution.", "content": "Conditions for purification of anti-Brucella antibodies by immunoadsorption and elution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219009"} {"pmid": "4219019", "title": "Further studies of human serum albumin in oral fluid.", "content": "Further studies of human serum albumin in oral fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219019"} {"pmid": "4219020", "title": "Pyrimidine-sensitive drosophila wing mutants: withered (whd), tilt (tt) and dumpy (dp).", "content": "Pyrimidine-sensitive drosophila wing mutants: withered (whd), tilt (tt) and dumpy (dp).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219020"} {"pmid": "4219021", "title": "Organization of replicative units in salivary gland chromosome bands.", "content": "Organization of replicative units in salivary gland chromosome bands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219021"} {"pmid": "4219022", "title": "Gonococci and gonorrhea, I. Gonococci.", "content": "Gonococci and gonorrhea, I. Gonococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219022"} {"pmid": "4219023", "title": "Host defenses in protein-calorie malnutrition.", "content": "Host defenses in protein-calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219023"} {"pmid": "4219025", "title": "Studies on the gastrulation of amphibian embryos: pseudopodia in the gastrula of Bufo bufo japonicus and their significance to gastrulation.", "content": "Studies on the gastrulation of amphibian embryos: pseudopodia in the gastrula of Bufo bufo japonicus and their significance to gastrulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219025"} {"pmid": "4219026", "title": "T and B lymphocytes.", "content": "T and B lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219026"} {"pmid": "4219027", "title": "The microscopy of parotid atrophy after ligation of Stensen's duct.", "content": "The microscopy of parotid atrophy after ligation of Stensen's duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219027"} {"pmid": "4219028", "title": "Proteins of the periodontium. Biochemical studies on the collagen and noncollagenous proteins of human gingivae.", "content": "Proteins of the periodontium. Biochemical studies on the collagen and noncollagenous proteins of human gingivae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219028"} {"pmid": "4219029", "title": "An intraoral model used for studies of fluoride incorporation in enamel.", "content": "An intraoral model used for studies of fluoride incorporation in enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219029"} {"pmid": "4219030", "title": "The coccidial nature and life-cycle of Sarcocystis.", "content": "The coccidial nature and life-cycle of Sarcocystis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219030"} {"pmid": "4219031", "title": "Laboratory studies on cefazolin--anti-inflammatory agent combinations with particular reference to tiaramide.", "content": "Laboratory studies on cefazolin--anti-inflammatory agent combinations with particular reference to tiaramide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219031"} {"pmid": "4219059", "title": "Providing a comprehensive district psychiatric service for the adult mentally ill. Appendix 3. Syndicate 'D' discussion paper.", "content": "Providing a comprehensive district psychiatric service for the adult mentally ill. Appendix 3. Syndicate 'D' discussion paper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219059"} {"pmid": "4219057", "title": "With liberty and psychosis for all.", "content": "With liberty and psychosis for all.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219057"} {"pmid": "4219062", "title": "Studies on the rate of diffusion-controlled reactions of enzymes. Spatial factor and force field factor.", "content": "Studies on the rate of diffusion-controlled reactions of enzymes. Spatial factor and force field factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219062"} {"pmid": "4219063", "title": "The phosphate depletion syndrome: relation to caloric intake and phosphate infusion.", "content": "The phosphate depletion syndrome: relation to caloric intake and phosphate infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219063"} {"pmid": "4219064", "title": "Prevention of ischemic myocardial contracture (stone heart).", "content": "Prevention of ischemic myocardial contracture (stone heart).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219064"} {"pmid": "4219065", "title": "Evolution of infarcts during reperfusion experiments in primates.", "content": "Evolution of infarcts during reperfusion experiments in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219065"} {"pmid": "4219067", "title": "Species variability in clinical antihuman antithymocyte globulin production: rabbit vs horse AHTG in primate skin graft survival.", "content": "Species variability in clinical antihuman antithymocyte globulin production: rabbit vs horse AHTG in primate skin graft survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219067"} {"pmid": "4219066", "title": "Cerebral etiology of the respiratory distress syndrome: universal response, with prevention by unilateral pulmonary denervation.", "content": "Cerebral etiology of the respiratory distress syndrome: universal response, with prevention by unilateral pulmonary denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219066"} {"pmid": "4219069", "title": "Trigeminothalamic projections from nucleus caudalis in primates.", "content": "Trigeminothalamic projections from nucleus caudalis in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219069"} {"pmid": "4219068", "title": "Intravenous feeding in hepatic failure.", "content": "Intravenous feeding in hepatic failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219068"} {"pmid": "4219070", "title": "Enhancement of peripheral nerve regeneration with triamcinolone after neurorrhaphy.", "content": "Enhancement of peripheral nerve regeneration with triamcinolone after neurorrhaphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219070"} {"pmid": "4219071", "title": "Modification of intestinal fistula output by elemental and intravenous alimentation.", "content": "Modification of intestinal fistula output by elemental and intravenous alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219071"} {"pmid": "4219072", "title": "Intravenous fat and glycerol: effect of heparin.", "content": "Intravenous fat and glycerol: effect of heparin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219072"} {"pmid": "4219073", "title": "Reversible inhibition of phagocytosis in anephric uremic patients.", "content": "Reversible inhibition of phagocytosis in anephric uremic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219073"} {"pmid": "4219075", "title": "Hepatic glucose balance and glucose tolerance during hemorrhagic shock.", "content": "Hepatic glucose balance and glucose tolerance during hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219075"} {"pmid": "4219074", "title": "Postoperative positive protein balance: accelerated oxidative glucose consumption.", "content": "Postoperative positive protein balance: accelerated oxidative glucose consumption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219074"} {"pmid": "4219083", "title": "Study of copper metabolism in kinky hair disease (Menkes' disease) and in hepatolenticular degeneration (Wilson's disease) utilizing 67Cu and radioactivity counting in the total body and various tissues.", "content": "Study of copper metabolism in kinky hair disease (Menkes' disease) and in hepatolenticular degeneration (Wilson's disease) utilizing 67Cu and radioactivity counting in the total body and various tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219083"} {"pmid": "4219084", "title": "Mapping of functional pathways in brain by autoradiographic survey of local cerebral metabolism.", "content": "Mapping of functional pathways in brain by autoradiographic survey of local cerebral metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219084"} {"pmid": "4219086", "title": "In search of the motor engram: a behavioral study of somatotopic localization in motor cortex of monkey.", "content": "In search of the motor engram: a behavioral study of somatotopic localization in motor cortex of monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219086"} {"pmid": "4219085", "title": "Diagnosis and treatment of experimental allergic encephalomyelitis in rhesus monkeys.", "content": "Diagnosis and treatment of experimental allergic encephalomyelitis in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219085"} {"pmid": "4219087", "title": "Primate experiments on oral sensation and morphogenesis.", "content": "Primate experiments on oral sensation and morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219087"} {"pmid": "4219088", "title": "Sensation and morphogenesis experimental and clinical findings following functional forward displacement of the mandible.", "content": "Sensation and morphogenesis experimental and clinical findings following functional forward displacement of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219088"} {"pmid": "4219089", "title": "Toxicity of Nerium oleander in the monkey (Cebus apella).", "content": "Toxicity of Nerium oleander in the monkey (Cebus apella).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219089"} {"pmid": "4219090", "title": "Penicillin and tetracycline sensitivity of Jamaican strains of gonococci.", "content": "Penicillin and tetracycline sensitivity of Jamaican strains of gonococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219090"} {"pmid": "4219092", "title": "Production of a rabbit anti-BKN antibody.", "content": "Production of a rabbit anti-BKN antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219092"} {"pmid": "4219095", "title": "Endogenous prostaglandins and the initiation of labor.", "content": "Endogenous prostaglandins and the initiation of labor. An attempt to define the role of the prostaglandins in human parturition must necessarily be fragmentary at the present time. However, there is no doubt that considerable progress has been made during the last few years and that the prostaglandins have been established as important key intermediates in the complex hormonal and mechanical events integrated in the process. Improved chemical methods for the determination of prostaglandins in body fluids and tissues as well as some evidence of indirect nature have contributed to a better understanding of this complex problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219095"} {"pmid": "4219096", "title": "Effect of a diphosphonate on para-articular ossification after total hip replacement.", "content": "Effect of a diphosphonate on para-articular ossification after total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219096"} {"pmid": "4219097", "title": "Amantadine.", "content": "Amantadine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219097"} {"pmid": "4219098", "title": "'Neuronal fall-out' in the ageing brain: a critical review of the quantitative data.", "content": "'Neuronal fall-out' in the ageing brain: a critical review of the quantitative data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219098"} {"pmid": "4219104", "title": "Phase III and health cost controls. No. L-89.", "content": "Phase III and health cost controls. No. L-89.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219104"} {"pmid": "4219106", "title": "Skilled nursing - the issues and their impact.", "content": "Skilled nursing - the issues and their impact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219106"} {"pmid": "4219100", "title": "DSCG and hyposensitization.", "content": "DSCG and hyposensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219100"} {"pmid": "4219103", "title": "Disodium cromoglycate, corticoids and bronchodilators in asthma therapy.", "content": "Disodium cromoglycate, corticoids and bronchodilators in asthma therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219103"} {"pmid": "4219116", "title": "The chemotherapy of plasma cell myeloma and related disorders.", "content": "The chemotherapy of plasma cell myeloma and related disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219116"} {"pmid": "4219118", "title": "Granuloma formation and its relation to chemotaxis. A discussion of the role of two groups of micro-organisms: the mycobacteria and the anaerobic coryneforms.", "content": "Granuloma formation and its relation to chemotaxis. A discussion of the role of two groups of micro-organisms: the mycobacteria and the anaerobic coryneforms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219118"} {"pmid": "4219117", "title": "Substances that attract eosinophils in vitro and in vivo, and that elicit blood eosinophilia.", "content": "Substances that attract eosinophils in vitro and in vivo, and that elicit blood eosinophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219117"} {"pmid": "4219134", "title": "Transport of intravenously administered horseradish peroxidase into the rat submaxillary saliva.", "content": "Transport of intravenously administered horseradish peroxidase into the rat submaxillary saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219134"} {"pmid": "4219133", "title": "Adjuvant effects of oral microorganisms on the immunological responses.", "content": "Adjuvant effects of oral microorganisms on the immunological responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219133"} {"pmid": "4219136", "title": "Fractionation of nucleic acids from Penicillium chrysogenum and associated ribonucleic acid viruses by selective exclusion and retention in agarose gels.", "content": "Fractionation of nucleic acids from Penicillium chrysogenum and associated ribonucleic acid viruses by selective exclusion and retention in agarose gels. Double-stranded nucleic acids from a strain of Penicillium chrysogenum containing RNA viruses were isolated by agarose-gel filtration, and separated into DNA and double-stranded RNA fractions by agarose-gel chromatography in 2.5m-NaCl. The DNA fraction contained less than 1% alkali-labile polynucleotides, and sedimented homogeneously at 8-10S in alkaline sucrose gradients. In CsCl gradients it tended to band in the density region of 1.66-1.72g/ml. It had a ;melting' temperature (T(m)) of 75 degrees C in 0.015m-NaCl-0.0015m-trisodium citrate, corresponding to 51.5mol% of G+C. The double-stranded RNA fraction did not contain detectable DNA. It could not band in CsCl up to a density of 1.78g/ml, and mainly consisted of a 14-15S RNA species with a T(m) of 88.5 degrees C in the above solvent, and a G+C content of 49.3 mol%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219136"} {"pmid": "4219135", "title": "Affinity labelling of the binding site of rabbit antibody. Evidence for the involvement of the hypervariable regions of the heavy chain.", "content": "Affinity labelling of the binding site of rabbit antibody. Evidence for the involvement of the hypervariable regions of the heavy chain. The binding sites of rabbit antibodies with affinity for the haptenic group 4-azido-2-nitrophenyl-lysine have been specifically labelled by photolysis of the hapten-antibody complex. The extent of covalent labelling was 0.5-0.9mol of hapten bound/mol of antibody and, by using an immunoadsorbent, antibody with 1.3mol of hapten/mol was obtained. The antibody was specifically labelled in the binding site and the ratio of labelling of heavy and light chains was in the range 3.3-5.0. The labelled heavy chains were cleaved by CNBr treatment and after reduction and alkylation of the intrachain bonds, were digested with trypsin. Evidence is presented that two regions of the heavy chain, positions 29-34 and 95-114, together contain about 80% of the label on the heavy chain; these two regions respectively include two of the hypervariable regions of rabbit heavy chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219135"} {"pmid": "4219137", "title": "The amine oxidases of human placenta and pregnancy plasma.", "content": "The amine oxidases of human placenta and pregnancy plasma. 1. The purification of monoamine oxidase and diamine oxidase from normal human term placental tissue is described. 2. The properties of these enzymes are reported and compared with the properties of unpurified human pregnancy plasma. 3. This comparison shows that the amine oxidase of pregnancy plasma has properties corresponding to purified placental diamine oxidase, suggesting a placental origin for the plasma enzyme system. 4. Detailed kinetic study of the purified placental diamine oxidase suggests that it has a Ping Pong sequence, a mechanism of action and rate-limiting step similar to the diamine oxidase of pig kidney. 5. It is suggested that the enzyme system is important in protecting the foeto-placental unit from excesses of biogenic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219137"} {"pmid": "4219138", "title": "The inhibition of human placental diamine oxidase by substrate analogues.", "content": "The inhibition of human placental diamine oxidase by substrate analogues. 1. The oxidation of p-dimethylaminomethylbenzylamine by purified placental diamine oxidase was followed by measuring the change in E(250) caused by the production of p-dimethylaminomethylbenzaldehyde. 2. The inhibition of this reaction by substrate analogues such as isothiouronium, guanidinium, dimethylsulphonium and trimethylammonium compounds was extensively studied. 3. The type and degree of inhibition by mono- and bis-onium compounds is described, and a theory is developed to explain the type of inhibition produced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219138"} {"pmid": "4219139", "title": "Stimulation of microsomal uridine diphosphate glucuronyltransferase by glucuronic acid derivatives.", "content": "Stimulation of microsomal uridine diphosphate glucuronyltransferase by glucuronic acid derivatives. The glucuronic acid adducts of 1-naphthol, 2-naphthol and 4-methylumbelliferone activate microsomal UDP-glucuronyltransferase (EC 2.4.1.17) when the enzyme is assayed with p-nitrophenol as aglycone. Phenyl glucuronide and oestriol 3beta-glucuronide also activate UDP-glucuronyltransferase. but to a lesser extent. Activation by glucuronides is not dependent on metal ions, but is blocked by prior treatment of microsomal fractions with p-chloromercuribenzoate. The kinetic mechanism of activation is concluded to be an increase in the affinity of the enzyme for UDP-glucuronic acid. Activation by 1-naphthyl glucuronide, at high concentrations of p-nitrophenol, is not affected by 1-naphthol. Apparently 1-naphthyl glucuronide activates the preparation by binding at a site that is separate from the site of glucuronidation of 1-naphthol. Further evidence for the existence of distinct effector sites for the glucuronides was provided by the finding that activation by glucuronides is inhibited competitively by aglycone glucosides. These glucosides do not inhibit the rate of glucuronidation of p-nitrophenol in the absence of glucuronide adducts, nor do they alter the rate of glucuronidation of 1-naphthol. When UDP-glucuronyltransferase is assayed with 1-naphthol as aglycone it is activated by p-nitrophenyl glucuronide, 4-methyl-umbelliferyl glucuronide and under appropriate conditions by its own glucuronide. These activations are similarly inhibited by aglycone glucosides. p-Nitrophenyl glucuronide also stimulates the rate of glucuronidation of o-aminophenol, o-aminobenzoate and bilirubin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219139"} {"pmid": "4219140", "title": "Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons.", "content": "Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons. The 3'-terminal sequence of 18S ribosomal RNA from Drosophila melanogaster and Saccharomyces cerevisiae was determined by stepwise degradation from the 3'-terminus and labelling with [(3)H]isoniazid. The sequence G-A-U-C-A-U-U-A(OH) was found at the 3'-terminus of both 18S rRNA species. Less extensive data for 18S RNA from a number of other eukaryotes are consistent with the same 3'-terminal sequence, and an identical sequence has previously been reported for the 3'-end of rabbit reticulocyte 18S rRNA (Hunt, 1970). These results suggest that the base sequence in this region is strongly conserved and may be identical in all eukaryotes. As the 3'-terminal hexanucleotide is complementary to eukaryotic terminator codons we discuss the possibility that the 3'-end of 18S rRNA may have a direct base-pairing role in the termination of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219140"} {"pmid": "4219141", "title": "Studies on the 3'-terminal sequences of the large ribosomal ribonucleic acid of different eukaryotes and those associated with \"hidden\" breaks in heart-dissociable insects 26S ribonucleic acid.", "content": "Studies on the 3'-terminal sequences of the large ribosomal ribonucleic acid of different eukaryotes and those associated with \"hidden\" breaks in heart-dissociable insects 26S ribonucleic acid. The 3'-terminal sequences associated with the large rRNA complex from a range of eukaryotes were determined after pancreatic or T(1)-ribonuclease digestion of RNA terminally labelled with [(3)H]isoniazid. In all higher eukaryotes examined except Drosophila melanogaster, the 3'-terminal sequences Y-G-U(OH) and G-C-U(OH) were demonstrated for the large RNA component(s) and for 6S RNA respectively. The 3'-terminal sequence of Saccharomyces cerevisiae 26S RNA was Y-G-U(OH) and that of 6S RNA Y-A-U-U-U(OH). Three 3'-terminal sequences were found in equimolar amounts in the heat-dissociable 26S rRNA characteristic of insect ribosomes. These were Y-G-U-G-U(OH), Y-C-G-U(OH) and G-C-U(OH) for cultured Antheraea eucalypti cells, Y-G-U(OH), Y-G-U(OH) and G-C-U(OH) for Galleria mellonella larvae and Y-C-G-A(OH), Y-G-U-A(OH) and G-Y-U-G(OH) for Drosophila melanogaster flies. Thus the introduction of the central scission in insect 26S rRNA results in the generation of a unique 3'-terminus and does not arise from random cleavage of the polynucleotide chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219141"} {"pmid": "4219143", "title": "Mechanism of the mutagenic activity of diazoacetylglycine derivatives.", "content": "Mechanism of the mutagenic activity of diazoacetylglycine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219143"} {"pmid": "4219144", "title": "Problems peculiar to the diagnosis and management of asthma in children.", "content": "Problems peculiar to the diagnosis and management of asthma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219144"} {"pmid": "4219183", "title": "Cellular changes in intrauterine malnutrition.", "content": "Cellular changes in intrauterine malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219183"} {"pmid": "4219184", "title": "Biochemical markers of intrauterine malnutrition.", "content": "Biochemical markers of intrauterine malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219184"} {"pmid": "4219185", "title": "Nitrogen balance during pregnancy.", "content": "Nitrogen balance during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219185"} {"pmid": "4219186", "title": "Chorionic gonadotropin synthesized in cultivated trophoblast.", "content": "Chorionic gonadotropin synthesized in cultivated trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219186"} {"pmid": "4219187", "title": "Chemical and immunological properties of iodocompounds associated with particulate fractions of hog thyroid cells.", "content": "Chemical and immunological properties of iodocompounds associated with particulate fractions of hog thyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219187"} {"pmid": "4219188", "title": "Crystals in hyperfunctioning rat parathyroid cells.", "content": "Crystals in hyperfunctioning rat parathyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219188"} {"pmid": "4219189", "title": "The effects of hyperthermia on pregnancy and prenatal development.", "content": "The effects of hyperthermia on pregnancy and prenatal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219189"} {"pmid": "4219193", "title": "Histopathological studies on liver tumorigenesis in rats treated with polychlorinated biphenyls.", "content": "Histopathological studies on liver tumorigenesis in rats treated with polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219193"} {"pmid": "4219204", "title": "Long-term cultures of leukocytes from leukemia and related disorders: methods and applications.", "content": "Long-term cultures of leukocytes from leukemia and related disorders: methods and applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219204"} {"pmid": "4219211", "title": "The X chromosome and the eye. The implications of recent microbiological models for clinical ophthalmology.", "content": "The X chromosome and the eye. The implications of recent microbiological models for clinical ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219211"} {"pmid": "4219212", "title": "Melanizing activity of blood & semen of rabbits of different coat colours.", "content": "Melanizing activity of blood & semen of rabbits of different coat colours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219212"} {"pmid": "4219216", "title": "Salmonella para A cultured from S. mansoni surgically recovered from man.", "content": "Salmonella para A cultured from S. mansoni surgically recovered from man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219216"} {"pmid": "4219214", "title": "Comparative infectivity for cattle of stabilates of Theileria lawrencei (Serengeti) derived from adult and nymphal ticks.", "content": "Comparative infectivity for cattle of stabilates of Theileria lawrencei (Serengeti) derived from adult and nymphal ticks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219214"} {"pmid": "4219215", "title": "Immunoglobulin class of antibodies in monkeys infected with Toxocara canis.", "content": "Immunoglobulin class of antibodies in monkeys infected with Toxocara canis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219215"} {"pmid": "4219218", "title": "Proteolytic activity of Pseudomonas aeruginosa on neopeptone agar medium.", "content": "Proteolytic activity of Pseudomonas aeruginosa on neopeptone agar medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219218"} {"pmid": "4219219", "title": "Defense mechanisms in the mouth and their possible role in the prevention of dental caries: a review.", "content": "Defense mechanisms in the mouth and their possible role in the prevention of dental caries: a review. The mouth harbors organisms in great abundance; yet their variety is limited and it is noteworthy that some species present in the mouth are not found elsewhere. There are many antibacterial substances in the mouth, some of which may contribute to the control of the microbial flora in the mouth. The activity of some is enhanced in the presence of specific antibody, e.g. lactoferrin, although others appear unaffected, e.g. lactoperoxidase. Opinions differ as to whether the level of immunoglobulins in human saliva can be related to caries. Although it has been established in principle that caries can be prevented in animals by means of vaccination, substantial work remains to be done before a vaccine will be available for testing in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219219"} {"pmid": "4219220", "title": "Keratin-filled pseudocysts of ducts of sebaceous glands in the vermilion border of the lip.", "content": "Keratin-filled pseudocysts of ducts of sebaceous glands in the vermilion border of the lip. Pathologic changes of free sebaceous glands are rare compared to those of the skin. Two keratin-filled pseudocysts which developed in the excretory ducts of sebaceous glands in the vermilion border of the lower lip in an 86-year-old woman are described. The entity is probably related to milia of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219220"} {"pmid": "4219221", "title": "Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs.", "content": "Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219221"} {"pmid": "4219227", "title": "The site of size constancy.", "content": "The site of size constancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219227"} {"pmid": "4219228", "title": "Factors in the health care system undergoing change.", "content": "Factors in the health care system undergoing change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219228"} {"pmid": "4219229", "title": "Whither virology? Trends and prospects in medical research.", "content": "Whither virology? Trends and prospects in medical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219229"} {"pmid": "4219230", "title": "Viral hepatitis and hepatitis B antigen: recent advances.", "content": "Viral hepatitis and hepatitis B antigen: recent advances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219230"} {"pmid": "4219234", "title": "Directional, reversible currents of blood flow in spinal cord arteries.", "content": "Directional, reversible currents of blood flow in spinal cord arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219234"} {"pmid": "4219225", "title": "Report on long term treatments with Sintisone (prednisolone-stearoylglycolate).", "content": "Report on long term treatments with Sintisone (prednisolone-stearoylglycolate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219225"} {"pmid": "4219226", "title": "Anesthesiologic considerations in psychiatric convulsive therapy.", "content": "Anesthesiologic considerations in psychiatric convulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219226"} {"pmid": "4219245", "title": "Violamycin, a new red-pigment antibiotic.", "content": "Violamycin, a new red-pigment antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219245"} {"pmid": "4219251", "title": "The cytopyge of ciliata. IV An experimental study of the ingestion, digestion and defaecation in Oxytricha fallax.", "content": "The cytopyge of ciliata. IV An experimental study of the ingestion, digestion and defaecation in Oxytricha fallax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219251"} {"pmid": "4219250", "title": "Occurrence and activity of ureolytic bacilli in soils.", "content": "Occurrence and activity of ureolytic bacilli in soils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219250"} {"pmid": "4219253", "title": "Stability of 131I-thyroxine and of 131-Itri-iodothyronine: the influence of radiolytic disintegration of certain diagnostic tests.", "content": "Stability of 131I-thyroxine and of 131-Itri-iodothyronine: the influence of radiolytic disintegration of certain diagnostic tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219253"} {"pmid": "4219255", "title": "Irradiation of small structures through the intact skull.", "content": "Irradiation of small structures through the intact skull. The physical conditions for producing minute disc-shaped lesions for functional radiation surgery by means of narrow beam irradiation are discussed. The intention was a treatment procedure for routine clinical use and with high physical and mechanical reproducibility. The possibilities of using high energy electrons, supervoltage roentgen radiation, gamma emitting nuclides or fast neutrons in a technique for routine clinical use were investigated. The radiation of choice taking physical properties, radiation biologic factors and practical circumstances into account was considered to be 60-Co gamma radiation. A treatment apparatus containing 179 60-Co sources within a spherical sector of 70 degrees latitude and 160 degrees longitude was constructed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219255"} {"pmid": "4219258", "title": "Geriatric nursing practice. Relying on nurses to improve nursing homes. No. G-94.", "content": "Geriatric nursing practice. Relying on nurses to improve nursing homes. No. G-94.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219258"} {"pmid": "4219262", "title": "Enzymes that repair or edit ultraviolet-irradiated DNA.", "content": "Enzymes that repair or edit ultraviolet-irradiated DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219262"} {"pmid": "4219261", "title": "Effects of chemicals on light-induced responses in the isolated carp retina.", "content": "Effects of chemicals on light-induced responses in the isolated carp retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219261"} {"pmid": "4219263", "title": "DNA repair in Bacillus subtilis: comparative studies with gamma-rays and ultraviolet light.", "content": "DNA repair in Bacillus subtilis: comparative studies with gamma-rays and ultraviolet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219263"} {"pmid": "4219264", "title": "Origin and development of life in relation to solar energy.", "content": "Origin and development of life in relation to solar energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219264"} {"pmid": "4219265", "title": "Immunological cross reactions among strains of Hydrogenomonas, Pseudomonas and Alcaligenes.", "content": "Immunological cross reactions among strains of Hydrogenomonas, Pseudomonas and Alcaligenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219265"} {"pmid": "4219266", "title": "Presence of growth factors for Methanobacterium ruminantium in both gram-positive and gram-negative bacteria.", "content": "Presence of growth factors for Methanobacterium ruminantium in both gram-positive and gram-negative bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219266"} {"pmid": "4219267", "title": "Localization and phenotypic expression of a Tol marker in Citrobacter freundii.", "content": "Localization and phenotypic expression of a Tol marker in Citrobacter freundii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219267"} {"pmid": "4219275", "title": "The nature of quantitative genetic variation in drosophila. II. Average dominance of abdominal bristle polygenes.", "content": "The nature of quantitative genetic variation in drosophila. II. Average dominance of abdominal bristle polygenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219275"} {"pmid": "4219273", "title": "The radioprotective effect of dimethyl sulfoxide on Bacillus subtilis cultures.", "content": "The radioprotective effect of dimethyl sulfoxide on Bacillus subtilis cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219273"} {"pmid": "4219274", "title": "Translation of rabbit haemoglobin mRNA in oocytes of the Queensland cane toad, Bufo marinus.", "content": "Translation of rabbit haemoglobin mRNA in oocytes of the Queensland cane toad, Bufo marinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219274"} {"pmid": "4219276", "title": "A re-evaluation of energy-independent calcium-ion binding by rat liver mitochondria.", "content": "A re-evaluation of energy-independent calcium-ion binding by rat liver mitochondria. The impermeability of the mitochondrial inner membrane to the chelator ethanedioxybis(ethylamine)tetra-acetic acid permits discrimination between Ca(2+) which has been transported to the internal (matrix) phase and Ca(2+) which binds to the external surfaces of the mitochondrion. With this technique, it is shown that ;energy-independent high-affinity' binding is a measure of carrier-mediated active Ca(2+) transport in respiration-inhibited mitochondria; the carrier also transports Ca(2+) to the internal phase after treatment with carbonyl cyanide m-chlorophenylhydrazone, but in this case the active-transport component is inhibited. The Ca(2+)-binding sites associated with the external membrane surfaces are similar in concentration and affinity for both inhibited and uncoupled mitochondria; it was not possible to measure external Ca(2+) binding which could be identified as carrier specific. The results are discussed in relation to the mechanism of mitochondrial Ca(2+) transport, and to previous studies of energy-independent Ca(2+) binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219276"} {"pmid": "4219278", "title": "Separation, purification and properties of beta-lactamase I and beta-lactamase II from Bacillus cereus 569/H/9.", "content": "Separation, purification and properties of beta-lactamase I and beta-lactamase II from Bacillus cereus 569/H/9. 1. A procedure was devised which is suitable for the isolation of beta-lactamase I and beta-lactamase II from Bacillus cereus 569/H/9 on a large scale. After adsorption on to Celite both enzymes were eluted in good yield and separated by chromatography on Sephadex CM-50. 2. beta-Lactamase I was separated into three main components by isoelectric focusing and into two components by chromatography. 3. The Zn(2+)-requiring beta-lactamase II obtained by this procedure had a lower molecular weight (22000) than beta-lactamase I (28000) and also differed from the latter in containing one cysteine residue. 4. The beta-lactamase II contained no carbohydrate, but showed the thermostability of the enzyme isolated earlier as a protein-carbohydrate complex. 5. Amino acid analyses and tryptic-digest ;maps' indicate that some degree of homology between beta-lactamase I and beta-lactamase II is possible, but that beta-lactamase I is not composed of the entire sequence of beta-lactamase II together with an additional peptide fragment. 6. A 6-methylpenicillin and a 7-methylcephalosporin showed much lower affinities for both enzymes than did penicillins and cephalosporins themselves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219278"} {"pmid": "4219279", "title": "Metal cofactor requirements of beta-lactamase II.", "content": "Metal cofactor requirements of beta-lactamase II. 1. The apoenzyme obtained on removal of Zn(2+) from beta-lactamase II from Bacillus cereus 569/H/9 showed less than 0.001% of the activity of the Zn(2+)-containing enzyme. 2. Removal of Zn(2+) led to a conformational change in the enzyme and partial unmasking of a thiol group. 3. Replacement of Zn(2+) by Co(2+), Cd(2+), Mn(2+) or Hg(2+) gave enzymes with significant, but lower, beta-lactamase activity. No activity was detected in the presence of Cu(2+), Ni(2+), Mg(2+) or Ca(2+). 4. Equilibrium dialysis indicated that the enzyme had at least two Zn(2+) binding sites. With benzylpenicillin as substrate the variation in activity with concentration of Zn(2+) indicated that activity paralleled binding of Zn(2+) to the site of highest affinity. 5. Replacement of Zn(2+) by Co(2+) and Cd(2+) gave enzymes with absorption bands at 340 and 245nm respectively, and raised the question of whether the thiol group in the enzyme is a metal-ion ligand. 6. Reduction of the product obtained by reaction of denatured beta-lactamase II with Ellman's reagent [5,5'-dithiobis-(2-nitrobenzoic acid)] gave a protein which could refold to produce beta-lactamase II activity in high yield.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219279"} {"pmid": "4219277", "title": "Metabolic adaptations during lactogenesis. Lactose synthesis in rabbit mammary tissue during pregnancy and lactation.", "content": "Metabolic adaptations during lactogenesis. Lactose synthesis in rabbit mammary tissue during pregnancy and lactation. Lactose biosynthesis and relevant enzymatic activity in rabbit mamma ry tissue during various stages of pregnancy and lactation are investigated by using a tissue-slice incubation method in order to understand the temporal relationships. Ovulation was induced in 27 New Zealand white rabbits and they were bred by artificial insemination. Sacrifice occurred on days 15, 24, and 29 of pregnancy, and day 2, 5, 8, 15, and 22 post partum. Nucleic acids were extracted and concentratons of DNA determined spectrophotometrically at 600 nm with diphenylamine reagent and RNA determined with orcinal reagent. The tissue incubations were made with (U-14C) glucose. (14C) lactose was then separated by paper chromatography from unchanged radioactive glucose. Enzyme analysis including determining the activities of phosphoglucomutase, UDP-glucose pyrophosphorylase, and UDP-glucose 4-epimerase. Lactose synthase was determined, as well as, hexokinase. A biphasic adaptation in the rate of lactose synthesis and in the RNA concentration was noted during lactogenesis. The 1st increase in the rate of lactose biosynthes is occurred between days 15 and 24 of pregnancy. A 2nd substantial increase was noted immediately post partum. The overall rate of lactose biosynthesis increased 12-fold from day 24 of pregnancy to day 15 of lactation post partum, and then decreased from 15 to 22 days post partum. The RNA concentration/g wet weight of tissue and the ratio of RNA/DNA closely represented the biphasic ability of the mammary-tissue slice to synthesize lactose. Increases in the activities of UDP-glucose 4-epimerase and lactose synthase were most closely correlated with increases in the rate of lactose biosynthesis. UDP-glucose pyrophosphor ylase activity was unrelated with the ability to synthesize lactose, and hexokinase and phosphoglucomutase activities were variable during pregnancy and lactation. Lactose synthase activity was present by day 15 of pregnancy, but the ability to synthesize lactose was undetected until day 24 of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219277"} {"pmid": "4219280", "title": "The macromolecular properties of blood-group-specific glycoproteins. Characterization of a series of fractions obtained by solvent fractionation.", "content": "The macromolecular properties of blood-group-specific glycoproteins. Characterization of a series of fractions obtained by solvent fractionation. 1. The glycoprotein components of a human ovarian-cyst fluid were isolated by a solvent [95% (w/w) phenol]-extraction procedure; the phenol-insoluble water-soluble glycoprotein was further fractionated by (NH(4))(2)SO(4) and by ethanol to yield eight fractions. 2. The fractions were analysed in terms of amino acids, fucose, galactose, N-acetylglucosamine, N-acetylgalactosamine and sialic acid. Variations occurred, particularly in the proportion of peptide; these were partly correlated with varying extent of serological activity. 3. The fractions were characterized physicochemically in terms of buoyant density and degree of spreading in a density gradient, sedimentation velocity and molecular weight; their partial specific volumes and specific refraction increments were also determined. 4. The fractions showed wide variations in their sedimentation-velocity and density-gradient patterns, and gave evidence of pauci-dispersity in density. The fraction regarded as the most typical blood-group-specific glycoprotein sedimented as a single rapidly spreading peak and was of high molecular weight. 5. Significant correlations were observed between the physical properties of the glycoprotein fractions and the amount of their peptide component. The buoyant densities and sedimentation coefficients varied in a manner that suggested the existence of two families of glycoproteins. 6. It is suggested that variability in the extent of glycosylation, or in the degree of cross-linking, might account for the two families of glycoproteins, and that the extent of cross-linkage might also be a factor determining the solubility of these glycoproteins in hot saturated (NH(4))(2)SO(4).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219280"} {"pmid": "4219281", "title": "The amino acid sequence of the peptide containing the thiol group of creatine kinase from normal and dystrophic chicken breast muscle. Comparison of some of the immunological properties of the antibodies developed in rabbits against these enzymes.", "content": "The amino acid sequence of the peptide containing the thiol group of creatine kinase from normal and dystrophic chicken breast muscle. Comparison of some of the immunological properties of the antibodies developed in rabbits against these enzymes. The major (14)C-labelled peptides from creatine kinase from normal and dystrophic chicken muscle obtained by carboxymethylating the reactive thiol groups with iodo[2-(14)C]acetic acid and digestion with trypsin were purified by ion-exchange chromatography on Dowex-50 (X2) and by paper electrophoresis. The chromatographic characteristics of the (14)C-labelled peptides, their electrophoretic mobilities at pH6.5, and their amino acid compositions were identical for the two enzymes. The sequence of amino acids around the essential thiol groups of creatine kinase from normal and dystrophic chicken muscle was shown to be Ile-Leu-Thr-CmCys-Pro-Ser-Asn-Leu-Gly-Thr-Gly-Leu-Arg (CmCys, carboxymethylcysteine). This sequence is almost identical with that for the creatine kinases in human and ox muscle and bovine brain and is very similar to that of arginine kinase from lobster muscle. Antibodies to the enzymes were raised in rabbits and their reaction with the creatine kinase from normal and dystrophic muscles in interfacial, immunodiffusion and immunoelectrophoretic experiments was studied. The cross-reaction between normal muscle creatine kinase and antisera against the dystrophic muscle enzyme (or vice versa) observed by immunodiffusion and by immunoelectrophoretic experiments further suggests that the enzymes from normal and dystrophic chicken muscle are similar in structure. The results of the present study, the identical amino acid sequence of the peptides containing the reactive thiol group from both the normal and dystrophic chicken muscle enzymes and the immunological similarities of the two enzymes are in accord with the similarity of the two enzymes observed by Roy et al. (1970).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219281"} {"pmid": "4219282", "title": "Polyribosomal and particulate distribution of lysyl- and phenylalanyl-transfer ribonucleic acid synthetases.", "content": "Polyribosomal and particulate distribution of lysyl- and phenylalanyl-transfer ribonucleic acid synthetases. 1. Only two aminoacyl-tRNA synthetases from Chinese hamster ovary cells are found associated with ribosomes and polyribosomes. 2. Phenylalanyl-tRNA synthetase activity is found with the 60S subunit, 80S monoribosome and individual polyribosomes. An additional 15S form of the enzyme is also seen. 3. Lysyl-tRNA synthetase activity is found in a form of about 20S and associated with ribosomal subunits and polyribosomes. The ribosomal subunits having lysyl-tRNA synthetase activity are about 6S larger than the bulk of the ribosomal subunits. 4. The lysyl- and phenylalanyl-tRNA synthetases found in different complexes have differential sensitivity to EDTA and centrifugation properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219282"} {"pmid": "4219284", "title": "Preliminary characterization of Thy-1.1 and Ag-B antigens from rat tissues solubilized in detergents.", "content": "Preliminary characterization of Thy-1.1 and Ag-B antigens from rat tissues solubilized in detergents. 1. A radioactive binding assay for Thy-1.1 alloantigen which functions in the presence of detergents was established by using glutaraldehyde-fixed thymocytes as target cells. Thy-1.1 activity in detergent extracts was then assayed by measuring inhibition of the binding assay. 2. Solubilization of Thy-1.1 from whole thymocytes, and their membranes by a large number of non-ionic detergents and deoxycholate was studied. In the same extracts Ag-B(4) histocompatibility antigenic activities were measured. With the exception of Nonidet P-40, the detergents did not affect the antigenicity of Thy-1.1, but only Lubrol-PX and deoxycholate gave effective solubilization as measured by activity remaining in the supernatant after centrifugation at 200000g for 40min. With Ag-B(4) antigen, Triton X-100, Triton X-67 and Nonidet P-40 gave effective solubilization as well as Lubrol-PX and deoxycholate. Solubilization of Thy-1.1 activity from leukaemia cells and a brain homogenate was also studied, but none of the non-ionic detergents gave satisfactory results with these tissues. 3. Extracts from thymocyte membranes were further examined by gel filtration and sucrose gradient centrifugation. The Thy-1.1 activity behaved as a single component in deoxycholate with a density similar to that of a globular protein, but in Lubrol-PX the antigen was contained in a low-density complex. In Lubrol-PX extracts Ag-B(4) was also found in aggregates not observed in deoxycholate. 4. The s(20,w) values for Thy-1.1 and Ag-B(4) antigens in deoxycholate were 2.4 and 4.4, and v values were 0.70 and 0.75 respectively. The Stokes radius observed for Thy-1.1 was 3.1nm and for Ag-B(4) 5.3nm. By using these values the molecular weights for the antigen-detergent complexes were calculated to be 28000 for Thy-1.1 and 100000 for Ag-B(4).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219284"} {"pmid": "4219283", "title": "The localization of a vitamin K-induced modification in an N-terminal fragment of human prothrombin.", "content": "The localization of a vitamin K-induced modification in an N-terminal fragment of human prothrombin. 1. The N-terminal fragment (PF-I) split off from prothrombin during coagulation was purified to homogeneity from human serum. 2. The apparent molecular weight is 27000+/-2000 in sodium dodecyl sulphate-polyacrylamide-gel electrophoresis, whereas a value of about 19600 is obtained by calculation based on amino acid and carbohydrate analyses. The N-terminal sequence is an Ala-Asx bond. The fragment contains about 16% carbohydrate, binds phospholipids in the presence of Ca(2+) and is adsorbed to BaSO(4). The pK(a) of its BaSO(4)-binding group(s) is 3.1-3.5. 3. By CNBr cleavage of fragment PF-I two peptides (C-1 and C-2) were obtained with molecular weights of about 5900 (C-2) and 12400 (C-1) on the basis of amino acid and carbohydrate analyses. Only the smaller (N-terminal) peptide is adsorbed to BaSO(4) and, since the ability of the whole protein to bind to BaSO(4) is known to be absent in samples obtained from patients treated with vitamin K antagonists, this peptide probably contains the site of a modification to the structure of the protein which occurs during biosynthesis and depends on vitamin K. This peptide does not contain hexosamine or sialic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219283"} {"pmid": "4219294", "title": "An evaluation of an agar gel diffusion test with crude and purified antigens in the diagnosis of hydatid disease.", "content": "An evaluation of an agar gel diffusion test with crude and purified antigens in the diagnosis of hydatid disease. The sensitivity of the indirect haemagglutination test for the diagnosis of hydatid disease, although high, is insufficient. Agar gel diffusion tests for the diagnosis of this disease have not received much attention in the past and have been considered unsatisfactory. The authors propose such a test and evaluate its results in comparison with those of the indirect haemagglutination test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219294"} {"pmid": "4219295", "title": "Seroepidemiology of Congo virus (related to the virus of Crimean haemorrhagic fever) in Nigeria.", "content": "Seroepidemiology of Congo virus (related to the virus of Crimean haemorrhagic fever) in Nigeria. A survey for neutralizing antibodies to Congo virus was carried out in Nigeria. Of a total sample population of 250, comprising 141 males and 109 females, 9 males and 15 females had antibody levels >/= 1.5 log neutralization index. In the age group 0-10 years 4 of 84 males and 14 of 79 females had antibody levels >/= 1.5 log neutralization index. There was no evidence of nonspecific antiviral activity in the sera tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219295"} {"pmid": "4219296", "title": "The ovicidal effect of selected chemicals against eggs of Echinococcus granulosus.", "content": "The ovicidal effect of selected chemicals against eggs of Echinococcus granulosus. The ovicidal activity of various chemicals against eggs of E. granulosus was evaluated by measuring infectivity to CF(1) mice after exposing the eggs to aqueous solutions of the chemicals for 1 h at room temperature. Significant reductions in infectivity were observed in eggs treated with Lugol's iodine, 0.015% ammonium dodecylbenzenesulfonate, 70% ethanol, or 5% or 10% glutaraldehyde. No cysts developed in 10 mice that received doses of 1 000 eggs treated with 5% glutaraldehyde, and only 1 of 10 mice developed cysts after exposure to eggs treated with 10% glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219296"} {"pmid": "4219357", "title": "Antitumor activity of cell-wall skeletons and peptidoglycolipids of mycobacteria and related microörganisms in mice and rabbits.", "content": "Antitumor activity of cell-wall skeletons and peptidoglycolipids of mycobacteria and related microörganisms in mice and rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219357"} {"pmid": "4219359", "title": "Organophosphorus poisoning.", "content": "Organophosphorus poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219359"} {"pmid": "4219361", "title": "Some genetic interrelationships in England and Wales. A methodological investigation.", "content": "Some genetic interrelationships in England and Wales. A methodological investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219361"} {"pmid": "4219360", "title": "[Diagnosis, epidemiology and prophylaxis of equine infectious anaemia (author's transl)].", "content": "[Diagnosis, epidemiology and prophylaxis of equine infectious anaemia (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219360"} {"pmid": "4219402", "title": "Some epidemiologic studies of transfusion-associated hepatitis.", "content": "Some epidemiologic studies of transfusion-associated hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219402"} {"pmid": "4219403", "title": "Circadian rhythm in Bence-Jones protein excretion by LOU rats bearing a transplantable immunocytoma, responsive to adrimycin treatment.", "content": "Circadian rhythm in Bence-Jones protein excretion by LOU rats bearing a transplantable immunocytoma, responsive to adrimycin treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219403"} {"pmid": "4219406", "title": "A brief discussion of a model for improving the cost effectiveness of a token economy in a rehabilitation setting.", "content": "A brief discussion of a model for improving the cost effectiveness of a token economy in a rehabilitation setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219406"} {"pmid": "4219410", "title": "Experimental endocarditis.", "content": "Experimental endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219410"} {"pmid": "4219427", "title": "Pseudomonas aeruginosa serotypes encountered in the American University Hospital (AUH), Beirut, Lebanon.", "content": "Pseudomonas aeruginosa serotypes encountered in the American University Hospital (AUH), Beirut, Lebanon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219427"} {"pmid": "4219428", "title": "Postnatal undernutrition and human brain development.", "content": "Postnatal undernutrition and human brain development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219428"} {"pmid": "4219430", "title": "Vasospasm and adrenergic innervation of circle of Willis.", "content": "Vasospasm and adrenergic innervation of circle of Willis. Cerebral vasospasm following the rupture of intracranial aneurysm presents perplexing situation, i.e. prolonged vasospasm results in cerebral infarct and too early relief causes recurrence of the bleeding. To understand mechanism underlying the cerebral vasospasm, catecholamine-containing sympathetic nerve plexus was examined in the arterial walls of the circle of Willis using rat, cat, dog and monkey using Falck-Hillarp's fluorescence method. The distribution of fluorescing nerve plexus was found to be essentially the same in the examination of all species. The distribution of the fluorescing fibers decreases in the following order; proximal anterior cerebral, internal carotid, distal anterior or proximal middle cerebral, and distal middle cerebral artery. The origin of the nerve plexus accompanying the basal cerebral arteries and the relation to the experimental cerebral vasospasm was investigated as detailed as they could.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219430"} {"pmid": "4219431", "title": "Islet cell transplantation.", "content": "Islet cell transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219431"} {"pmid": "4219432", "title": "End-stage diabetic nephropathy. Discussion: general topics and summation.", "content": "End-stage diabetic nephropathy. Discussion: general topics and summation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219432"} {"pmid": "4219437", "title": "A computer-aided diagnostic system using a small desk-top computer-calculator.", "content": "A computer-aided diagnostic system using a small desk-top computer-calculator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219437"} {"pmid": "4219447", "title": "An accurate method for measuring immunodiffusion rings.", "content": "An accurate method for measuring immunodiffusion rings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219447"} {"pmid": "4219448", "title": "Infusion of synthetic TRH in the diagnosis of thyroid and pituitary dysfunction.", "content": "Infusion of synthetic TRH in the diagnosis of thyroid and pituitary dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219448"} {"pmid": "4219450", "title": "Comparison of short wave diathermy and pulsed electromagnetic energy in treatment of soft tissue injuries.", "content": "Comparison of short wave diathermy and pulsed electromagnetic energy in treatment of soft tissue injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219450"} {"pmid": "4219452", "title": "Technique for the visualization of precipitation bands obtained by gel immunodiffusion reactions for hepatitis B antigen detection.", "content": "Technique for the visualization of precipitation bands obtained by gel immunodiffusion reactions for hepatitis B antigen detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219452"} {"pmid": "4219454", "title": "Clinical evaluation of Morfolep.", "content": "Clinical evaluation of Morfolep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219454"} {"pmid": "4219455", "title": "Angina pectoris and nitroglycerin.", "content": "Angina pectoris and nitroglycerin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219455"} {"pmid": "4219460", "title": "Split and extremely thin glomerular basement membranes in hereditary nephropathy (Alport's syndrome).", "content": "Split and extremely thin glomerular basement membranes in hereditary nephropathy (Alport's syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219460"} {"pmid": "4219462", "title": "The mode of growth of experimental metastases in rabbit femora.", "content": "The mode of growth of experimental metastases in rabbit femora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219462"} {"pmid": "4219461", "title": "Aorta valve replacement using autologous fascia lata transplants. Late morphological changes, an electron microscopic study.", "content": "Aorta valve replacement using autologous fascia lata transplants. Late morphological changes, an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219461"} {"pmid": "4219463", "title": "Electron microscopy of thrombocytes in the orthotopic porcine liver homograft during the late rejection. (Phagocytosis of thrombocytes by Kupffer cells).", "content": "Electron microscopy of thrombocytes in the orthotopic porcine liver homograft during the late rejection. (Phagocytosis of thrombocytes by Kupffer cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219463"} {"pmid": "4219464", "title": "Hypothalamic neurosecretory nuclei and nucleus habenularis of epithalamus in essential hypertension.", "content": "Hypothalamic neurosecretory nuclei and nucleus habenularis of epithalamus in essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219464"} {"pmid": "4219465", "title": "Liver schistosomiasis and primary biliary cirrhosis. A clinico-pathological study.", "content": "Liver schistosomiasis and primary biliary cirrhosis. A clinico-pathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219465"} {"pmid": "4219467", "title": "Laboratoty techniques in rabies: tissue culture methods.", "content": "Laboratoty techniques in rabies: tissue culture methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219467"} {"pmid": "4219468", "title": "Laboratory techniques in rabies: the complement fixation test.", "content": "Laboratory techniques in rabies: the complement fixation test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219468"} {"pmid": "4219469", "title": "Safety precautions in handling rabies virus.", "content": "Safety precautions in handling rabies virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219469"} {"pmid": "4219470", "title": "Laboratory techniques in rabies: hamgglutination and hemagglutination-inhibition tests.", "content": "Laboratory techniques in rabies: hamgglutination and hemagglutination-inhibition tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219470"} {"pmid": "4219471", "title": "Passive haemagglutination test for rabies antibodies.", "content": "Passive haemagglutination test for rabies antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219471"} {"pmid": "4219472", "title": "Laboratory techniques in rabies: gel-diffusion techniques.", "content": "Laboratory techniques in rabies: gel-diffusion techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219472"} {"pmid": "4219473", "title": "Laboratory techniques in rabies: electron microscopy.", "content": "Laboratory techniques in rabies: electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219473"} {"pmid": "4219474", "title": "Purification of rabies virus and isolation of its components.", "content": "Purification of rabies virus and isolation of its components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219474"} {"pmid": "4219475", "title": "Aluminium phosphate method for rabies virus purification.", "content": "Aluminium phosphate method for rabies virus purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219475"} {"pmid": "4219476", "title": "A radioimmune assay for rabies binding antibody.", "content": "A radioimmune assay for rabies binding antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219476"} {"pmid": "4219477", "title": "Laboratory technics in rabies: general considerations in vaccine production.", "content": "Laboratory technics in rabies: general considerations in vaccine production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219477"} {"pmid": "4219478", "title": "An assessment of laboratory techniques in the diagnosis and prevention of rabies and in rabies research.", "content": "An assessment of laboratory techniques in the diagnosis and prevention of rabies and in rabies research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219478"} {"pmid": "4219479", "title": "Laboratory technics in rabies: Semple-type vaccine.", "content": "Laboratory technics in rabies: Semple-type vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219479"} {"pmid": "4219480", "title": "Laboratory techniques in rabies: Fermi-type vaccine.", "content": "Laboratory techniques in rabies: Fermi-type vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219480"} {"pmid": "4219481", "title": "Laboratory techniques in rabies: phenolized, freeze-dried sheep brain vaccine. A. Method used in the USSR.", "content": "Laboratory techniques in rabies: phenolized, freeze-dried sheep brain vaccine. A. Method used in the USSR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219481"} {"pmid": "4219482", "title": "Laboratory techniques in rabies: phenolized, freeze-dried sheep brain vaccine. B. Method used at the Pasteur Institute, Paris.", "content": "Laboratory techniques in rabies: phenolized, freeze-dried sheep brain vaccine. B. Method used at the Pasteur Institute, Paris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219482"} {"pmid": "4219483", "title": "Laboratory techniques in rabies: suckling rat brain vaccine.", "content": "Laboratory techniques in rabies: suckling rat brain vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219483"} {"pmid": "4219486", "title": "Laboratory techniques in rabies: ultraviolet-light irradiation for inactivation of vaccines.", "content": "Laboratory techniques in rabies: ultraviolet-light irradiation for inactivation of vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219486"} {"pmid": "4219485", "title": "Laboratory techniques in rabies: suckling rabbit brain vaccine.", "content": "Laboratory techniques in rabies: suckling rabbit brain vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219485"} {"pmid": "4219484", "title": "Laboratory techniques in rabies: suckling mouse brain vaccine.", "content": "Laboratory techniques in rabies: suckling mouse brain vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219484"} {"pmid": "4219487", "title": "Laboratory techniques in rabies: chicken-embryo vaccine.", "content": "Laboratory techniques in rabies: chicken-embryo vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219487"} {"pmid": "4219490", "title": "Laboratory techniques in rabies: tissue culture vaccines for animals.", "content": "Laboratory techniques in rabies: tissue culture vaccines for animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219490"} {"pmid": "4219488", "title": "Laboratory techniques in rabies: duck-embryo vaccine.", "content": "Laboratory techniques in rabies: duck-embryo vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219488"} {"pmid": "4219489", "title": "Laboratory techniques in rabies: vaccine for man prepared in human diploid cells.", "content": "Laboratory techniques in rabies: vaccine for man prepared in human diploid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219489"} {"pmid": "4219491", "title": "Laboratory techniques in rabies: general considerations in safety and potency testing.", "content": "Laboratory techniques in rabies: general considerations in safety and potency testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219491"} {"pmid": "4219492", "title": "Laboratory techniques in rabies: Habel test for potency.", "content": "Laboratory techniques in rabies: Habel test for potency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219492"} {"pmid": "4219493", "title": "Laboratory techniques in rabies: modified Habel test for potency.", "content": "Laboratory techniques in rabies: modified Habel test for potency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219493"} {"pmid": "4219494", "title": "Laboratory techniques in rabies: the NIH test for potency.", "content": "Laboratory techniques in rabies: the NIH test for potency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219494"} {"pmid": "4219495", "title": "Laboratory techniques in rabies: guineapig potency test for chicken-embryo vaccine.", "content": "Laboratory techniques in rabies: guineapig potency test for chicken-embryo vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219495"} {"pmid": "4219496", "title": "Laboratory techniques in rabies: shipments of specimens, and techniques for preparation of animal tissues.", "content": "Laboratory techniques in rabies: shipments of specimens, and techniques for preparation of animal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219496"} {"pmid": "4219498", "title": "Laboratory techniques in rabies: test for neuroallergenic activity.", "content": "Laboratory techniques in rabies: test for neuroallergenic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219498"} {"pmid": "4219497", "title": "Laboratory techniques in rabies: the antibody binding test for vaccine potency.", "content": "Laboratory techniques in rabies: the antibody binding test for vaccine potency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219497"} {"pmid": "4219499", "title": "Production of antirabies serum of animal origin.", "content": "Production of antirabies serum of animal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219499"} {"pmid": "4219500", "title": "Preparation of antirabies immunoglobulin of animal origin: method used in the USSR.", "content": "Preparation of antirabies immunoglobulin of animal origin: method used in the USSR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219500"} {"pmid": "4219501", "title": "Preparation of antirabies immunoglobulin of human origin.", "content": "Preparation of antirabies immunoglobulin of human origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219501"} {"pmid": "4219502", "title": "Quantitative assay and potency test of antirabies serum and immunoglobulin.", "content": "Quantitative assay and potency test of antirabies serum and immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219502"} {"pmid": "4219503", "title": "Laboratory techniques in rabies: methods of calculation.", "content": "Laboratory techniques in rabies: methods of calculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219503"} {"pmid": "4219504", "title": "A rapid method for fluorescein labelling of rabies antibodies.", "content": "A rapid method for fluorescein labelling of rabies antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219504"} {"pmid": "4219505", "title": "Laboratory techniques in rabies: cell monolayer plaque test.", "content": "Laboratory techniques in rabies: cell monolayer plaque test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219505"} {"pmid": "4219506", "title": "Proposed safety tests for inactivated rabies vaccine prepared in cell cultures.", "content": "Proposed safety tests for inactivated rabies vaccine prepared in cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219506"} {"pmid": "4219507", "title": "A rapid tissue culture test for determining rabies neutralizing antibody.", "content": "A rapid tissue culture test for determining rabies neutralizing antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219507"} {"pmid": "4219508", "title": "The immunoperoxidase reaction for demonstration of rabies virus.", "content": "The immunoperoxidase reaction for demonstration of rabies virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219508"} {"pmid": "4219510", "title": "Laboratory techniques in rabies: the fluorescent antibody test.", "content": "Laboratory techniques in rabies: the fluorescent antibody test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219510"} {"pmid": "4219509", "title": "Laboratory techniques in rabies: rapid microscopic examination for Negri bodies and preparation of specimens for biological test.", "content": "Laboratory techniques in rabies: rapid microscopic examination for Negri bodies and preparation of specimens for biological test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219509"} {"pmid": "4219511", "title": "Laboratory techniques in rabies: the mouse inoculation test.", "content": "Laboratory techniques in rabies: the mouse inoculation test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219511"} {"pmid": "4219512", "title": "Laboratory techniques in rabies: the virus neutralization index test in mice.", "content": "Laboratory techniques in rabies: the virus neutralization index test in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219512"} {"pmid": "4219523", "title": "Fixation with mercury salts.", "content": "Fixation with mercury salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219523"} {"pmid": "4219543", "title": "[Two simple but useful methods for the analysis of dyes: gel-filtration chromatography and solvent extraction].", "content": "[Two simple but useful methods for the analysis of dyes: gel-filtration chromatography and solvent extraction].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219543"} {"pmid": "4219555", "title": "The importance and histopathology of hypothalamic changes in animals inoculated intracerebrally with Högyes' fixed strain of rabies virus.", "content": "The importance and histopathology of hypothalamic changes in animals inoculated intracerebrally with Högyes' fixed strain of rabies virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219555"} {"pmid": "4219556", "title": "The choriocapillaris.", "content": "The choriocapillaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219556"} {"pmid": "4219557", "title": "Submacular choroidal vascular pattern. Experimental fluorescein fundus angiographic studies.", "content": "Submacular choroidal vascular pattern. Experimental fluorescein fundus angiographic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219557"} {"pmid": "4219558", "title": "The long posterior ciliary arteries. An experimental study.", "content": "The long posterior ciliary arteries. An experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219558"} {"pmid": "4219564", "title": "Temperature-induced change in helicity of the inherently dissymmetrical disulfide group in cyclocystine.", "content": "Temperature-induced change in helicity of the inherently dissymmetrical disulfide group in cyclocystine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219564"} {"pmid": "4219566", "title": "The problem of species variations.", "content": "The problem of species variations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219566"} {"pmid": "4219582", "title": "Pleiotropic mutations affecting sporulation conditions and the syntheses of extracellular enzymes in Bacillus subtilis 168.", "content": "Pleiotropic mutations affecting sporulation conditions and the syntheses of extracellular enzymes in Bacillus subtilis 168.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219582"} {"pmid": "4219581", "title": "Identification of the structural gene for sucrase in Bacillus subtilis Marburg.", "content": "Identification of the structural gene for sucrase in Bacillus subtilis Marburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219581"} {"pmid": "4219567", "title": "[Antibacterial activity in vitro of cyclacillin (author's transl)].", "content": "[Antibacterial activity in vitro of cyclacillin (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219567"} {"pmid": "4219583", "title": "The isozymes of phosphorylase kinase in various mammalian tissues.", "content": "The isozymes of phosphorylase kinase in various mammalian tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219583"} {"pmid": "4219584", "title": "Cranial bony changes in ocular neurofibromatosis.", "content": "Cranial bony changes in ocular neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219584"} {"pmid": "4219585", "title": "A rare association of neurofibromatosis with Marfan's syndrome.", "content": "A rare association of neurofibromatosis with Marfan's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219585"} {"pmid": "4219586", "title": "Antibiotics and war injuries.", "content": "Antibiotics and war injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219586"} {"pmid": "4219587", "title": "In vitro studies linking induction of spontaneous antibody synthesis to an accessory cell with persisting antigen on its surface.", "content": "In vitro studies linking induction of spontaneous antibody synthesis to an accessory cell with persisting antigen on its surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219587"} {"pmid": "4219576", "title": "The value of serological techniques for the differentiation between Verticillum Albo-atrum Reink. & Berth. and V. dahliae Kleb.", "content": "The value of serological techniques for the differentiation between Verticillum Albo-atrum Reink. & Berth. and V. dahliae Kleb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219576"} {"pmid": "4219588", "title": "A comparison of autoimmunity and experimental allergic thyroiditis in strain 2 and Hartley strain guinea pigs.", "content": "A comparison of autoimmunity and experimental allergic thyroiditis in strain 2 and Hartley strain guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219588"} {"pmid": "4219578", "title": "Serological studies on coffee rust.", "content": "Serological studies on coffee rust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219578"} {"pmid": "4219589", "title": "Effects of pretreatment of mice with BCG cell walls in saline on subsequent vaccination with BCG oil droplet vaccine.", "content": "Effects of pretreatment of mice with BCG cell walls in saline on subsequent vaccination with BCG oil droplet vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219589"} {"pmid": "4219590", "title": "Sterilization of Listeria monocytogenes by guinea pig peritoneal exudate cell cultures.", "content": "Sterilization of Listeria monocytogenes by guinea pig peritoneal exudate cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219590"} {"pmid": "4219591", "title": "Quantitative analysis of the 51Cr release cytotoxicity assay for cytotoxic lymphocytes.", "content": "Quantitative analysis of the 51Cr release cytotoxicity assay for cytotoxic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219591"} {"pmid": "4219592", "title": "Exclusion of cooperating T cells as targets for heterologous anti-mu antiserum.", "content": "Exclusion of cooperating T cells as targets for heterologous anti-mu antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219592"} {"pmid": "4219593", "title": "Immunological memory in tuberculosis. I. Influence of persisting viable organisms.", "content": "Immunological memory in tuberculosis. I. Influence of persisting viable organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219593"} {"pmid": "4219594", "title": "Immunosuppression of congenitally athymic (nude) mice with heterologous anti-immunoglobulin heavy-chain antisera.", "content": "Immunosuppression of congenitally athymic (nude) mice with heterologous anti-immunoglobulin heavy-chain antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219594"} {"pmid": "4219595", "title": "Ontogeny of B lymphocytes. I. In vitro appearance of Ig-bearing lymphocytes.", "content": "Ontogeny of B lymphocytes. I. In vitro appearance of Ig-bearing lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219595"} {"pmid": "4219598", "title": "Development of lymphocyte populations in the human foetal thymus and spleen.", "content": "Development of lymphocyte populations in the human foetal thymus and spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219598"} {"pmid": "4219600", "title": "B-cell markers on lymphoblasts in acute lymphoblastic leukaemia.", "content": "B-cell markers on lymphoblasts in acute lymphoblastic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219600"} {"pmid": "4219599", "title": "Monoclonal lymphocyte population in human plasma cell myeloma.", "content": "Monoclonal lymphocyte population in human plasma cell myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219599"} {"pmid": "4219603", "title": "Fine structural alterations in the developing spermatids of Musca domestica induced by the PCB, Aroclor 1254.", "content": "Fine structural alterations in the developing spermatids of Musca domestica induced by the PCB, Aroclor 1254.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219603"} {"pmid": "4219605", "title": "Androgens in prenatal development: behavior changes in nonhuman primates and men.", "content": "Androgens in prenatal development: behavior changes in nonhuman primates and men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219605"} {"pmid": "4219609", "title": "Thyrotropin releasing hormone induced thyrotropin release in euthyroid men. Effect of ethinyl oestradiol priming.", "content": "Thyrotropin releasing hormone induced thyrotropin release in euthyroid men. Effect of ethinyl oestradiol priming.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219609"} {"pmid": "4219611", "title": "Intravenous alimentation with a mixture of fat, carbohydrates and amino acids in small immature newborn infants--a preliminary report.", "content": "Intravenous alimentation with a mixture of fat, carbohydrates and amino acids in small immature newborn infants--a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219611"} {"pmid": "4219614", "title": "Proceedings: Neuron activities in prefrontal cortex during gazing behavior in monkeys.", "content": "Proceedings: Neuron activities in prefrontal cortex during gazing behavior in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219614"} {"pmid": "4219615", "title": "Proceedings: Prefrontal activities in monkeys inmaturely trained in delayed response task.", "content": "Proceedings: Prefrontal activities in monkeys inmaturely trained in delayed response task.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219615"} {"pmid": "4219616", "title": "Proceedings: Neuron activities in the posterior parietal association areas and visual orientation.", "content": "Proceedings: Neuron activities in the posterior parietal association areas and visual orientation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219616"} {"pmid": "4219619", "title": "Proceedings: Activities of motor cortex neurons during simple reaction time responses in monkeys.", "content": "Proceedings: Activities of motor cortex neurons during simple reaction time responses in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219619"} {"pmid": "4219622", "title": "Proceedings: Plasma levels of luteinizing hormone during menstrual cycle and their response to gonadectomy in Japanese monkeys.", "content": "Proceedings: Plasma levels of luteinizing hormone during menstrual cycle and their response to gonadectomy in Japanese monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219622"} {"pmid": "4219623", "title": "Editorial: Suppression of Rh-sensitisation by the use of anti-D immunoglobulin.", "content": "Editorial: Suppression of Rh-sensitisation by the use of anti-D immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219623"} {"pmid": "4219624", "title": "Genetic code limit organisms--do they exist?", "content": "Genetic code limit organisms--do they exist?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219624"} {"pmid": "4219625", "title": "Characterization of the primary structural homology between the 16s ribosomal RNAs of Escherichia coli and Bacillus megaterium by oligomer cataloging.", "content": "Characterization of the primary structural homology between the 16s ribosomal RNAs of Escherichia coli and Bacillus megaterium by oligomer cataloging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219625"} {"pmid": "4219629", "title": "A comparison of betamethasone valerate aerosol and sodium cromoglycate in children with reversible airways obstruction.", "content": "A comparison of betamethasone valerate aerosol and sodium cromoglycate in children with reversible airways obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219629"} {"pmid": "4219630", "title": "The effect of betamethasone valerate aerosol in exercise-induced asthma.", "content": "The effect of betamethasone valerate aerosol in exercise-induced asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219630"} {"pmid": "4219663", "title": "Haemodynamics in animals.", "content": "Haemodynamics in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219663"} {"pmid": "4219664", "title": "Psychotherapy research in schizophrenia--another view of present reality.", "content": "Psychotherapy research in schizophrenia--another view of present reality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219664"} {"pmid": "4219665", "title": "Patterns of psychiatric utilization by diagnosed schizophrenics in the Kansas City area.", "content": "Patterns of psychiatric utilization by diagnosed schizophrenics in the Kansas City area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219665"} {"pmid": "4219666", "title": "Studies on interaction of 4-nitroquinoline 1-oxide with RNA of hamster embryo cells.", "content": "Studies on interaction of 4-nitroquinoline 1-oxide with RNA of hamster embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219666"} {"pmid": "4219681", "title": "Electron microscopic study of plasma cells in immunoproliferative diseases. Preliminary report.", "content": "Electron microscopic study of plasma cells in immunoproliferative diseases. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219681"} {"pmid": "4219683", "title": "Problems of macromolecule ultrafiltration.", "content": "Problems of macromolecule ultrafiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219683"} {"pmid": "4219684", "title": "Perspectives offered by enzyme binding in polymeric membranes.", "content": "Perspectives offered by enzyme binding in polymeric membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219684"} {"pmid": "4219685", "title": "Extracapillary proliferative glomerulonephritis so-called malignant glomerulonephritis.", "content": "Extracapillary proliferative glomerulonephritis so-called malignant glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219685"} {"pmid": "4219686", "title": "Unilateral renovascular hypertension in the dog.", "content": "Unilateral renovascular hypertension in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219686"} {"pmid": "4219687", "title": "Pharmacology of diuretics: a progress report, 1968--1971.", "content": "Pharmacology of diuretics: a progress report, 1968--1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219687"} {"pmid": "4219688", "title": "Diuretics in chronic renal insufficiency.", "content": "Diuretics in chronic renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219688"} {"pmid": "4219690", "title": "Metabolic complications in the use of diuretics.", "content": "Metabolic complications in the use of diuretics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219690"} {"pmid": "4219689", "title": "Diuretics in the treatment of arterial hypertension.", "content": "Diuretics in the treatment of arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219689"} {"pmid": "4219691", "title": "Biochemical studies of the glomerular basement membrane in the diseased kidney.", "content": "Biochemical studies of the glomerular basement membrane in the diseased kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219691"} {"pmid": "4219692", "title": "Trapping of urea and ammonia in the gut of uremic patients.", "content": "Trapping of urea and ammonia in the gut of uremic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219692"} {"pmid": "4219694", "title": "Biochemical studies of the glomerular basement membrane in the normal kidney.", "content": "Biochemical studies of the glomerular basement membrane in the normal kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219694"} {"pmid": "4219693", "title": "Pathogenesis of the uremic state: a new perspective.", "content": "Pathogenesis of the uremic state: a new perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219693"} {"pmid": "4219695", "title": "The structural basis of glomerular filtration.", "content": "The structural basis of glomerular filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219695"} {"pmid": "4219698", "title": "Artificial membranes.", "content": "Artificial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219698"} {"pmid": "4219697", "title": "Role of anti-basement membrane immunity in human glomerulonephritis.", "content": "Role of anti-basement membrane immunity in human glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219697"} {"pmid": "4219696", "title": "Glomerular filtration of macromolecules.", "content": "Glomerular filtration of macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219696"} {"pmid": "4219699", "title": "Interface reactions between artificial membranes and blood.", "content": "Interface reactions between artificial membranes and blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219699"} {"pmid": "4219700", "title": "Cryoglobulinemia in glomerulonephritis exclusive of general diseases.", "content": "Cryoglobulinemia in glomerulonephritis exclusive of general diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219700"} {"pmid": "4219701", "title": "Ultrastructural lesions of the glomerular basement membrane in hereditary chronic nephritis.", "content": "Ultrastructural lesions of the glomerular basement membrane in hereditary chronic nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219701"} {"pmid": "4219702", "title": "Intravascular coagulation and nephropathies.", "content": "Intravascular coagulation and nephropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219702"} {"pmid": "4219703", "title": "Acute renal failure and intravascular coagulation.", "content": "Acute renal failure and intravascular coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219703"} {"pmid": "4219704", "title": "Renal disease and fibrinogen degradation products.", "content": "Renal disease and fibrinogen degradation products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219704"} {"pmid": "4219705", "title": "Home dialysis in the United Kingdom: experience in a regional center.", "content": "Home dialysis in the United Kingdom: experience in a regional center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219705"} {"pmid": "4219706", "title": "Maintenance home dialysis: four years' experience in Languedoc-Roussillon.", "content": "Maintenance home dialysis: four years' experience in Languedoc-Roussillon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219706"} {"pmid": "4219707", "title": "One hundred patients on home dialysis.", "content": "One hundred patients on home dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219707"} {"pmid": "4219708", "title": "Drugs in the treatment of hyperuricemia.", "content": "Drugs in the treatment of hyperuricemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219708"} {"pmid": "4219709", "title": "The Lesch-Nyhan syndrome.", "content": "The Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219709"} {"pmid": "4219711", "title": "Recent data on uric acid lithiasis.", "content": "Recent data on uric acid lithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219711"} {"pmid": "4219710", "title": "Hyperuricemia in children, with the exception of the Lesch-Nyhan syndrome.", "content": "Hyperuricemia in children, with the exception of the Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219710"} {"pmid": "4219712", "title": "Ureteral diverticulosis. A new case and a review of the literature.", "content": "Ureteral diverticulosis. A new case and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219712"} {"pmid": "4219713", "title": "Ultrastructural concepts of drug metabolism. I. The hepatocyte: structure and function.", "content": "Ultrastructural concepts of drug metabolism. I. The hepatocyte: structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219713"} {"pmid": "4219714", "title": "Ultrastructural concepts of drug metabolism. II. The hepatocyte: phenobarbital and microsomal enzyme induction.", "content": "Ultrastructural concepts of drug metabolism. II. The hepatocyte: phenobarbital and microsomal enzyme induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219714"} {"pmid": "4219715", "title": "A comprehensive approach to the treatment of drug dependence.", "content": "A comprehensive approach to the treatment of drug dependence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219715"} {"pmid": "4219716", "title": "Ultrastructural concepts of drug metabolism. III. The hepatocyte: membranes, lipids, and alcohol.", "content": "Ultrastructural concepts of drug metabolism. III. The hepatocyte: membranes, lipids, and alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219716"} {"pmid": "4219722", "title": "The detection and differentiation of the products of the human carbonic anhydrase loci, CAI and CAII using fluorogenic substrates.", "content": "The detection and differentiation of the products of the human carbonic anhydrase loci, CAI and CAII using fluorogenic substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219722"} {"pmid": "4219723", "title": "Further studies on erythrocyte inorganic pyrophosphatase: an examination of different mammalian species and human-Chinese hamster hybrid cells.", "content": "Further studies on erythrocyte inorganic pyrophosphatase: an examination of different mammalian species and human-Chinese hamster hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219723"} {"pmid": "4219728", "title": "Glycoprotein biosynthesis in splenic cells. IV. Subcellular localization of glycosyl - transferases.", "content": "Glycoprotein biosynthesis in splenic cells. IV. Subcellular localization of glycosyl - transferases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219728"} {"pmid": "4219736", "title": "The economics of health.", "content": "The economics of health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219736"} {"pmid": "4219735", "title": "A clinical and sociomedical study for defaulting tuberculosis treatment.", "content": "A clinical and sociomedical study for defaulting tuberculosis treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219735"} {"pmid": "4219737", "title": "Development of functional connexions in the mammalian visual system.", "content": "Development of functional connexions in the mammalian visual system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219737"} {"pmid": "4219738", "title": "Selection of visual targets for the initiation of saccadic eye movements.", "content": "Selection of visual targets for the initiation of saccadic eye movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219738"} {"pmid": "4219739", "title": "Single unit firing patterns in the vestibular nuclei related to voluntary eye movements and passive body rotation in conscious monkeys.", "content": "Single unit firing patterns in the vestibular nuclei related to voluntary eye movements and passive body rotation in conscious monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219739"} {"pmid": "4219740", "title": "The role of vestibular and neck afferents during eye-head coordination in the monkey.", "content": "The role of vestibular and neck afferents during eye-head coordination in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219740"} {"pmid": "4219741", "title": "Development of sensorially-guided reaching in infant monkeys.", "content": "Development of sensorially-guided reaching in infant monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219741"} {"pmid": "4219742", "title": "Movement without proprioception.", "content": "Movement without proprioception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219742"} {"pmid": "4219743", "title": "Some examples of programmed limb movements.", "content": "Some examples of programmed limb movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219743"} {"pmid": "4219744", "title": "The activity of dentate neurons during an arm movement sequence.", "content": "The activity of dentate neurons during an arm movement sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219744"} {"pmid": "4219745", "title": "Relation of basal ganglia, cerebellum, and motor cortex units to ramp and ballistic limb movements.", "content": "Relation of basal ganglia, cerebellum, and motor cortex units to ramp and ballistic limb movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219745"} {"pmid": "4219746", "title": "Single unit recording in the caudate nucleus during sessions with elaborate movements in the awake monkey.", "content": "Single unit recording in the caudate nucleus during sessions with elaborate movements in the awake monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219746"} {"pmid": "4219747", "title": "Pyramidal tract discharge in relation to movement performance in monkeys with partial anaesthesia of the movind hand.", "content": "Pyramidal tract discharge in relation to movement performance in monkeys with partial anaesthesia of the movind hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219747"} {"pmid": "4219748", "title": "Role of occipito-frontal cortico-cortical connections in visual guidance of relatively independent hand and finger movements in rhesus monkeys.", "content": "Role of occipito-frontal cortico-cortical connections in visual guidance of relatively independent hand and finger movements in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219748"} {"pmid": "4219749", "title": "Gating of motor cortex reflexes by prior instruction.", "content": "Gating of motor cortex reflexes by prior instruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219749"} {"pmid": "4219750", "title": "Cortical load compensation during voluntary elbow movements.", "content": "Cortical load compensation during voluntary elbow movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219750"} {"pmid": "4219751", "title": "Short review. Prospects for cancer immunochemotherapy.", "content": "Short review. Prospects for cancer immunochemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219751"} {"pmid": "4219752", "title": "Structure-activity correlations for N-substituted N-thioformylhydroxylamines on bacterial cells.", "content": "Structure-activity correlations for N-substituted N-thioformylhydroxylamines on bacterial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219752"} {"pmid": "4219753", "title": "Formation of the red neotetrazolium formazan by reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in the presence of triton X-100.", "content": "Formation of the red neotetrazolium formazan by reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in the presence of triton X-100.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219753"} {"pmid": "4219754", "title": "Studies on dextranase. V. Activation of dextranase from Penicillium funiculosum IAM 7013 by Co2+.", "content": "Studies on dextranase. V. Activation of dextranase from Penicillium funiculosum IAM 7013 by Co2+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219754"} {"pmid": "4219758", "title": "Experiments with cholera toxin detoxified with glutaraldehyde.", "content": "Experiments with cholera toxin detoxified with glutaraldehyde. Studies on the production, purification, and detoxification of cholera toxin are reported. The toxin was first partially purified with aluminium hydroxide and further purification was effected with Bio Gel A-5m and Sephadex G-75. The toxins were detoxified with glutaraldehyde; the toxoids so obtained, when injected into the skin of rabbits, appeared to have no residual toxicity. All the toxins were immunogenic. The toxoid partially purified with aluminium hydroxide retained most of its immunizing capacity, but the highly purified toxoids did not retain their capacity to stimulate antibody production in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219758"} {"pmid": "4219759", "title": "Experiments on monkeys with cholera toxin partially purified and detoxified with formol and glycine.", "content": "Experiments on monkeys with cholera toxin partially purified and detoxified with formol and glycine. Cholera toxoid partially purified and detoxified with formol and glycine and inoculated in monkeys proved safe. Histological examination revealed no changes in the skin of the animals treated. Blood samples taken from monkeys immunized with 2 doses of toxoid 12 days after the second inoculation revealed appreciable levels of antitoxin in the animals that had received two 100-mug doses of toxoid. The monkeys vaccinated with toxoid, when inoculated with challenge doses of cholera toxin, had the capacity to neutralize the toxin. Detoxification with formol and glycine may be the first step towards the preparation of a highly purified, innocuous, and antigenic cholera toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219759"} {"pmid": "4219757", "title": "Immunology of schistosomiasis.", "content": "Immunology of schistosomiasis. This Memorandum, after summarizing the life cycle of the different species of human schistosome, reviews the present knowledge of the immunology of schistosomiasis. Each stage of the parasite contains antigen that may stimulate an immune response. However, at the moment there are no accepted serological in vitro tests that correlate with protection; this develops only after the host has experienced a living infection, which suggests that the stimulation of immunity is due to some metabolic process involving the release of protective antigen. The adult worm, however, seems to be able to escape the immune mechanism of the host. Specific antigens are also released by the eggs, and the immune response against these antigens seems to cause granuloma formation around the egg itself. The granuloma is the main lesion found in schistosomiasis. Evidence for protective immunity in experimental animals and man is reviewed, together with the possible mechanism by which the adult worm escapes the immune response of the host. A review of methods used for the diagnosis of schistosomiasis and a list of recommendations for further research are also included.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219757"} {"pmid": "4219760", "title": "The natural history of the antibody response to breast antigens.", "content": "The natural history of the antibody response to breast antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219760"} {"pmid": "4219764", "title": "Immunological competence in non-human primates: differences observed in four species.", "content": "Immunological competence in non-human primates: differences observed in four species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219764"} {"pmid": "4219765", "title": "Surface immunoglobulins in chronic lymphatic leukaemia, macroglobulinaemia and myelomatosis.", "content": "Surface immunoglobulins in chronic lymphatic leukaemia, macroglobulinaemia and myelomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219765"} {"pmid": "4219766", "title": "Properdin levels in systemic lupus erythematosus and membranoproleferative glomerulonephritis.", "content": "Properdin levels in systemic lupus erythematosus and membranoproleferative glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219766"} {"pmid": "4219768", "title": "Rosette formation by mouse lymphocytes. II. T-cell specificities in a CRL subpopulation.", "content": "Rosette formation by mouse lymphocytes. II. T-cell specificities in a CRL subpopulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219768"} {"pmid": "4219776", "title": "Adhesion of human blood platelets to glass and polymer surfaces. I. Studies with platelets in plasma.", "content": "Adhesion of human blood platelets to glass and polymer surfaces. I. Studies with platelets in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219776"} {"pmid": "4219777", "title": "In vitro granulocyte-platelet rosette formation mediated by an IgG immunoglobulin.", "content": "In vitro granulocyte-platelet rosette formation mediated by an IgG immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219777"} {"pmid": "4219778", "title": "Biochemical foundations of preventive medicine: the study of abnormal enzymes.", "content": "Biochemical foundations of preventive medicine: the study of abnormal enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219778"} {"pmid": "4219775", "title": "Need for long-term care of the inhabitants of Helsinki city.", "content": "Need for long-term care of the inhabitants of Helsinki city.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219775"} {"pmid": "4219783", "title": "Beta-lactam antibiotics. I. Comparative structure--activity relationships of 6-acylaminopenicillanic acid derivatives and their 6-(D-alpha-acylaminophenylacetamido) penicillanic acid analogues.", "content": "Beta-lactam antibiotics. I. Comparative structure--activity relationships of 6-acylaminopenicillanic acid derivatives and their 6-(D-alpha-acylaminophenylacetamido) penicillanic acid analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219783"} {"pmid": "4219784", "title": "Therapeutic efficacy of bicyclomycin for shigellosis experimentally induced in rhesus monkeys.", "content": "Therapeutic efficacy of bicyclomycin for shigellosis experimentally induced in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219784"} {"pmid": "4219785", "title": "Bacteriological studies on the combined action of aminoglycoside antibiotics and synthetic penicillins against Pseudomonas aeruginosa.", "content": "Bacteriological studies on the combined action of aminoglycoside antibiotics and synthetic penicillins against Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219785"} {"pmid": "4219786", "title": "Ultrasound localization of the kidneys for closed renal biopsy.", "content": "Ultrasound localization of the kidneys for closed renal biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219786"} {"pmid": "4219787", "title": "The ultrasonic determination of renal transplant volume.", "content": "The ultrasonic determination of renal transplant volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219787"} {"pmid": "4219788", "title": "The ultrasound findings in an obstructed afferent loop.", "content": "The ultrasound findings in an obstructed afferent loop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219788"} {"pmid": "4219789", "title": "The diagnosis of sextuplets by ultrasound-a case report.", "content": "The diagnosis of sextuplets by ultrasound-a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219789"} {"pmid": "4219774", "title": "The effect of phenylalanine, glycine, lysine, thymidine and thalidomide upon the developmental age in Drosophila melanogaster.", "content": "The effect of phenylalanine, glycine, lysine, thymidine and thalidomide upon the developmental age in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219774"} {"pmid": "4219769", "title": "Immunoelectrophoretic analysis of surface antigens in vegetative cells and spores of Bacillus cereus.", "content": "Immunoelectrophoretic analysis of surface antigens in vegetative cells and spores of Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219769"} {"pmid": "4219790", "title": "Ultrasound diagnosis of and cyst puncture guidance for a second unilateral renal cyst.", "content": "Ultrasound diagnosis of and cyst puncture guidance for a second unilateral renal cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219790"} {"pmid": "4219791", "title": "A simple technique to determine the extent of abdominal aortic aneurysms of B-mode sonography.", "content": "A simple technique to determine the extent of abdominal aortic aneurysms of B-mode sonography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219791"} {"pmid": "4219792", "title": "Renal pelvic lipomatosis: a sonographic evaluation.", "content": "Renal pelvic lipomatosis: a sonographic evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219792"} {"pmid": "4219794", "title": "The gray scale echographic appearance of thyroid malignancy.", "content": "The gray scale echographic appearance of thyroid malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219794"} {"pmid": "4219795", "title": "B-mode ultrasonic examination of the testes.", "content": "B-mode ultrasonic examination of the testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219795"} {"pmid": "4219793", "title": "Ultrasonic evaluation of postpartum sepsis with retained Dalkon shield.", "content": "Ultrasonic evaluation of postpartum sepsis with retained Dalkon shield.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219793"} {"pmid": "4219796", "title": "Simple device for the calibration of ultrasonic calipers.", "content": "Simple device for the calibration of ultrasonic calipers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219796"} {"pmid": "4219797", "title": "Acoustic microscopy of mammalian kidney.", "content": "Acoustic microscopy of mammalian kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219797"} {"pmid": "4219798", "title": "Pitfalls in the echographic evaluation of pancreatic disease.", "content": "Pitfalls in the echographic evaluation of pancreatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219798"} {"pmid": "4219799", "title": "Gray scale ultrasonography in the diagnosis of thyroid swellings.", "content": "Gray scale ultrasonography in the diagnosis of thyroid swellings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219799"} {"pmid": "4219800", "title": "Comparison of pelvic ultrasonography and pneumography for ovarian size.", "content": "Comparison of pelvic ultrasonography and pneumography for ovarian size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219800"} {"pmid": "4219801", "title": "The inhibitory action of diazoxide on uterine activity in the subhuman primate: Placental transfer and effect on the fetus.", "content": "The inhibitory action of diazoxide on uterine activity in the subhuman primate: Placental transfer and effect on the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219801"} {"pmid": "4219803", "title": "The case against ankle taping.", "content": "The case against ankle taping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219803"} {"pmid": "4219811", "title": "Failure of dialysis concentrate as a bactericidal agent.", "content": "Failure of dialysis concentrate as a bactericidal agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219811"} {"pmid": "4219812", "title": "Enzyme therapy in Fabry's disease by renal transplantation.", "content": "Enzyme therapy in Fabry's disease by renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219812"} {"pmid": "4219805", "title": "The ankle: soft tissue injuries.", "content": "The ankle: soft tissue injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219805"} {"pmid": "4219804", "title": "Ankle injuries in sports.", "content": "Ankle injuries in sports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219804"} {"pmid": "4219813", "title": "A new subcutaneous prosthetic A-V shunt: advantageous over the standard Quinton-Scribner shunt and A-V fistula.", "content": "A new subcutaneous prosthetic A-V shunt: advantageous over the standard Quinton-Scribner shunt and A-V fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219813"} {"pmid": "4219802", "title": "The swivel football shoe: a controlled study.", "content": "The swivel football shoe: a controlled study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219802"} {"pmid": "4219814", "title": "Prediction of long term combined imuran ALG dosage.", "content": "Prediction of long term combined imuran ALG dosage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219814"} {"pmid": "4219815", "title": "New long-stay inpatients.", "content": "New long-stay inpatients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219815"} {"pmid": "4219816", "title": "New long-stay patients.", "content": "New long-stay patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219816"} {"pmid": "4219817", "title": "The hospital census as a sampling frame for studies of long-term psychiatric care.", "content": "The hospital census as a sampling frame for studies of long-term psychiatric care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219817"} {"pmid": "4219818", "title": "Influence of nitroglycerin on the isolated blood-perfused dog heart.", "content": "Influence of nitroglycerin on the isolated blood-perfused dog heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219818"} {"pmid": "4219819", "title": "Effect of calcium ions on the optical rotation of the troponin complex, troponin A and troponin B.", "content": "Effect of calcium ions on the optical rotation of the troponin complex, troponin A and troponin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219819"} {"pmid": "4219834", "title": "Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus.", "content": "Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus. 3-Hexulose phosphate synthase and phospho-3-hexuloisomerase were purified 40- and 150-fold respectively from methane-grown Methylococcus capsulatus. The molecular weights of the enzymes were approximately 310000 and 67000 respectively, as determined by gel filtration. Dissociation of 3-hexulose phosphate synthase into subunits of molecular weight approx. 49000 under conditions of low pH or low ionic strength was observed. Within the range of compounds tested, 3-hexulose phosphate synthase is specific for formaldehyde and d-ribulose 5-phosphate (forward reaction) and d-arabino-3-hexulose 6-phosphate (reverse reaction), and phospho-3-hexuloisomerase is specific for d-arabino-3-hexulose 6-phosphate (forward reaction) and d-fructose 6-phosphate (reverse reaction). A bivalent cation is essential for activity and stability of 3-hexulose phosphate synthase; phospho-3-hexuloisomerase is inhibited by many bivalent cations. The pH optima of the two enzymes are 7.0 and 8.3 respectively and the equilibrium constants are 4.0x10(-5)m and 1.9x10(2)m respectively. The apparent Michaelis constants for 3-hexulose phosphate synthase are: d-ribulose 5-phosphate, 8.3x10(-5)m; formaldehyde, 4.9x10(-4)m; d-arabino-3-hexulose 6-phosphate, 7.5x10(-5)m. The apparent Michaelis constants for phospho-3-hexuloisomerase are: d-arabino-3-hexulose 6-phosphate, 1.0x10(-4)m; d-fructose 6-phosphate, 1.1x10(-3)m.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219834"} {"pmid": "4219838", "title": "Nature of the antigen present in the cerebrospinal fluid and serum of patients with group A meningococcal meningitis.", "content": "Nature of the antigen present in the cerebrospinal fluid and serum of patients with group A meningococcal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219838"} {"pmid": "4219839", "title": "Specific antisera to Clr. Quantitation of Clr in normal and pathological human sera.", "content": "Specific antisera to Clr. Quantitation of Clr in normal and pathological human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219839"} {"pmid": "4219840", "title": "Sequential cell-mediated immune responses in experimental gingivitis in man.", "content": "Sequential cell-mediated immune responses in experimental gingivitis in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219840"} {"pmid": "4219842", "title": "Inactivation of C1 in rheumatoid synovial fluid, purfied C1 and C1 esterase, by gold compounds.", "content": "Inactivation of C1 in rheumatoid synovial fluid, purfied C1 and C1 esterase, by gold compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219842"} {"pmid": "4219843", "title": "Analytical study of salivary immunoglobulins in multiple myeloma.", "content": "Analytical study of salivary immunoglobulins in multiple myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219843"} {"pmid": "4219844", "title": "PHA-induced lymphocyte transformations in leucocyte cultures from malarious, malnourished and control Gambian children.", "content": "PHA-induced lymphocyte transformations in leucocyte cultures from malarious, malnourished and control Gambian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219844"} {"pmid": "4219845", "title": "Deficit of spatial reversal in monkey with frontal lesions.", "content": "Deficit of spatial reversal in monkey with frontal lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219845"} {"pmid": "4219846", "title": "Some physiological and behavioural changes associated with oestrus and pregnancy in the squirrel monkey (Saimiri sciureus).", "content": "Some physiological and behavioural changes associated with oestrus and pregnancy in the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219846"} {"pmid": "4219847", "title": "Glutaraldehyde fixation of boar spermatozoa for acrosome evaluation.", "content": "Glutaraldehyde fixation of boar spermatozoa for acrosome evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219847"} {"pmid": "4219848", "title": "Radiosensitivity of synchronized Tetrahymena pyriformis W. cells.", "content": "Radiosensitivity of synchronized Tetrahymena pyriformis W. cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219848"} {"pmid": "4219849", "title": "A proline-dependent ATP-32Pi exchange in Bacillus sutilis B3 producing mycobacillin.", "content": "A proline-dependent ATP-32Pi exchange in Bacillus sutilis B3 producing mycobacillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219849"} {"pmid": "4219850", "title": "Seasonal variation in personal health expenditure of rural populations.", "content": "Seasonal variation in personal health expenditure of rural populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219850"} {"pmid": "4219851", "title": "Comparative sensitivity of suckling mice and Vero cells for primary isolation of chikungunya virus.", "content": "Comparative sensitivity of suckling mice and Vero cells for primary isolation of chikungunya virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219851"} {"pmid": "4219852", "title": "Studies on host-parasite relationships of Ilan strain of Schistosoma japonicum in animals. 2. Worm recovery rate.", "content": "Studies on host-parasite relationships of Ilan strain of Schistosoma japonicum in animals. 2. Worm recovery rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219852"} {"pmid": "4219854", "title": "The effects of intravenous protein--calorie supplementation on the tissue composition of postoperative body weight loss.", "content": "The effects of intravenous protein--calorie supplementation on the tissue composition of postoperative body weight loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219854"} {"pmid": "4219855", "title": "Successful resuscitation in diabetic ketoacidosis: a strong case for the use of bicarbonate.", "content": "Successful resuscitation in diabetic ketoacidosis: a strong case for the use of bicarbonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219855"} {"pmid": "4219857", "title": "Lactic acidosis and hyperamylasaemia associated with phenformin therapy.", "content": "Lactic acidosis and hyperamylasaemia associated with phenformin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219857"} {"pmid": "4219856", "title": "Gonococcaemia with arthritis, dermatitis and myocarditis.", "content": "Gonococcaemia with arthritis, dermatitis and myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219856"} {"pmid": "4219862", "title": "Relationships between intraocular pressure and the morphology of the outflow apparatus.", "content": "Relationships between intraocular pressure and the morphology of the outflow apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219862"} {"pmid": "4219863", "title": "Neurologic effects of repeated exposures to high-pressure heliox atmospheres.", "content": "Neurologic effects of repeated exposures to high-pressure heliox atmospheres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219863"} {"pmid": "4219864", "title": "Biosynthesis of rat small seminal fructose as influenced by in vitro tissue excitation.", "content": "Biosynthesis of rat small seminal fructose as influenced by in vitro tissue excitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219864"} {"pmid": "4219865", "title": "Clinical observation of the prevention of RH isoimmunization with immunoglobulin anti-D.", "content": "Clinical observation of the prevention of RH isoimmunization with immunoglobulin anti-D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219865"} {"pmid": "4219866", "title": "Protein malnutrition: correlation between anthropometric and biochemical assessment.", "content": "Protein malnutrition: correlation between anthropometric and biochemical assessment. Three hundred and eighty-six children aged 12-59 months, suffering from protein-calorie malnutrition were studied. Middle arm circumference and triceps skin-fold measurements were taken and from these values, middle arm muscular circumference was calclated. Simultaneously, the serum amino-acid balance was determined. The same measurements were carried out in 132 healthy control children of the same age group. These showed that middle arm muscular circumference does not change within the age groups studied, and with its value the amino-acid balance showed an inverse correlation. It is concluded that the severity of protein imbalance in malnutrition can be estimated on the basis of both middle arm muscular circumference and amino-acid balance. In view of its simple technique the former parameter is given preference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219866"} {"pmid": "4219867", "title": "Metabolic and hormonal effects of alternate infusion of hypertonic glucose and aminosol-glucose in premature infants.", "content": "Metabolic and hormonal effects of alternate infusion of hypertonic glucose and aminosol-glucose in premature infants. The metabolic and hormonal effects of a short term (24-36 hrs), alternating intravenous administration of hypertonic (16%) glucose and Aminosol-glucose were investigated in premature infants. The majority of the infants under 1 500 g showed pathological signs and did not tolerate oral feeding. The purpose of the study was to explore an intravenous alimentation program capable of ensuring an improved amino acid utilization in terms of nitrogen balance, and to prevent some of the adverse effects of the amino acid mixture. It was thought that the hormonal state created by 16% glucose might increase the capacity of the tissues to utilize the amino acids. The relevant findings were as follows. 1. Plasma free fatty acids and amino acids decreased, plasma insulin and growth hormone increased markedly in response to 16% glucose. The plasma aminogram indicated a profound redistribution of amino acids. 2. Aminosol-glucose infusion after the 16% glucose, increased the concentration of amino acids, but only to the starting level. Thus the previously decreased alpha-amino nitrogen content allowed to avoid a hyperaminoacidaemia and a marked distortion of the plasma amino acid pattern. Administration of the amino acid-glucose mixture usually failed to maintain the previously stimulated insulin and growth hormone secretion. 3. The hormonal and metabolis responses to the intermittent infusion of hypertonic glucose and Aminosol-glucose were not associated with an improved nitrogen utilization. More than 50% of the administered amino acid nitrogen was excreted. 4. The metabolic acidosis observed under these condition was found to be variable, and practically compensated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219867"} {"pmid": "4219870", "title": "The lethal interaction between the genes prune (pn) and killer of prune (Kpn) in Drosophila melanogaster.", "content": "The lethal interaction between the genes prune (pn) and killer of prune (Kpn) in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219870"} {"pmid": "4219871", "title": "Toxicity and mutagenicity of dimethyl sulfoxide in two strains of Drosophila melanogaster.", "content": "Toxicity and mutagenicity of dimethyl sulfoxide in two strains of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219871"} {"pmid": "4219872", "title": "Newborn genetic screening as a concept in health care delivery: a critique.", "content": "Newborn genetic screening as a concept in health care delivery: a critique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219872"} {"pmid": "4219873", "title": "Mass screening and genetic counseling in mendelian disorders.", "content": "Mass screening and genetic counseling in mendelian disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219873"} {"pmid": "4219874", "title": "Circulating tissue antigens. I. Tissue antigens in serum of patients with diseases involving injury of the liver and of other organs.", "content": "Circulating tissue antigens. I. Tissue antigens in serum of patients with diseases involving injury of the liver and of other organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219874"} {"pmid": "4219875", "title": "Plasma volume expansion and increased serum viscosity in myeloma and macroglobulinaemia.", "content": "Plasma volume expansion and increased serum viscosity in myeloma and macroglobulinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219875"} {"pmid": "4219876", "title": "The autosomal recessive mode of inheritance of C1r deficiency in a large Puerto Rican family.", "content": "The autosomal recessive mode of inheritance of C1r deficiency in a large Puerto Rican family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219876"} {"pmid": "4219879", "title": "Heterophilic antibodies in relation to malarial infection: population and experimental studies.", "content": "Heterophilic antibodies in relation to malarial infection: population and experimental studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219879"} {"pmid": "4219880", "title": "Comparative study on two labelled antimonial drugs, Bilharcid and tartar emetic using monkeys.", "content": "Comparative study on two labelled antimonial drugs, Bilharcid and tartar emetic using monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219880"} {"pmid": "4219882", "title": "The innervation of the human vestibular sensory regions.", "content": "The innervation of the human vestibular sensory regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219882"} {"pmid": "4219881", "title": "The fate and behaviour of antimonial drugs labelled with 124Sb in bilharzial subjets.", "content": "The fate and behaviour of antimonial drugs labelled with 124Sb in bilharzial subjets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219881"} {"pmid": "4219883", "title": "Xenografts.", "content": "Xenografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219883"} {"pmid": "4219884", "title": "Porcine aortic valves for replacement of human heart valves.", "content": "Porcine aortic valves for replacement of human heart valves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219884"} {"pmid": "4219889", "title": "Viral cardiomyopathy.", "content": "Viral cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219889"} {"pmid": "4219890", "title": "Pathology of Chagas' cardiomyopathy.", "content": "Pathology of Chagas' cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219890"} {"pmid": "4219891", "title": "Experimental cardiomyopathies in poikilotherms.", "content": "Experimental cardiomyopathies in poikilotherms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219891"} {"pmid": "4219892", "title": "Natural history of diverse cardiomyopathies.", "content": "Natural history of diverse cardiomyopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219892"} {"pmid": "4219894", "title": "Lepers, madmen--who's next?", "content": "Lepers, madmen--who's next?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219894"} {"pmid": "4219895", "title": "The diagnosis and psychopathology of schizophrenia in New York and London.", "content": "The diagnosis and psychopathology of schizophrenia in New York and London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219895"} {"pmid": "4219896", "title": "Study of protein reactivity in rat liver ribosomes. Effect of RNA addition to autodigested ribosomes.", "content": "Study of protein reactivity in rat liver ribosomes. Effect of RNA addition to autodigested ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219896"} {"pmid": "4219897", "title": "Studies of the RNA and protein moieties of the larger subribosomal particle of rabbit reticulocytes.", "content": "Studies of the RNA and protein moieties of the larger subribosomal particle of rabbit reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219897"} {"pmid": "4219898", "title": "Hydatid cyst of the brain as an epileptogenic factor.", "content": "Hydatid cyst of the brain as an epileptogenic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219898"} {"pmid": "4219899", "title": "Effect of epileptogenic stimulation on the acetylcholine content of rat hippocampus.", "content": "Effect of epileptogenic stimulation on the acetylcholine content of rat hippocampus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219899"} {"pmid": "4219907", "title": "Some aspects of immunity in patients with cystic fibrosis.", "content": "Some aspects of immunity in patients with cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219907"} {"pmid": "4219908", "title": "Studies of serum complement in the hypocomplementaemic nephritides.", "content": "Studies of serum complement in the hypocomplementaemic nephritides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219908"} {"pmid": "4219909", "title": "Diffuse normolipaemic plane xanthomatosis. An abnormal complement component profile.", "content": "Diffuse normolipaemic plane xanthomatosis. An abnormal complement component profile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219909"} {"pmid": "4219910", "title": "The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique.", "content": "The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219910"} {"pmid": "4219917", "title": "Estrogen-binding in vitro by DMBA-induced rat mammary tumors: its relationship to hormone responsiveness.", "content": "Estrogen-binding in vitro by DMBA-induced rat mammary tumors: its relationship to hormone responsiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219917"} {"pmid": "4219935", "title": "About the normal values of the acid-base and oxygen indices in small laboratory animals--rats and rabbits.", "content": "About the normal values of the acid-base and oxygen indices in small laboratory animals--rats and rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219935"} {"pmid": "4219936", "title": "Endogenic humoral effects on the formation of antitoxins.", "content": "Endogenic humoral effects on the formation of antitoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219936"} {"pmid": "4219937", "title": "A radiographic study of the ethmoidal latticed labyrinths from birth to the age of thirteen.", "content": "A radiographic study of the ethmoidal latticed labyrinths from birth to the age of thirteen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219937"} {"pmid": "4219938", "title": "Histochemical studies of some dehydrogenases in dental tooth germ in vivo and in culture.", "content": "Histochemical studies of some dehydrogenases in dental tooth germ in vivo and in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219938"} {"pmid": "4219939", "title": "Relationship between the respiratory and lipopexic function of the lungs in some non-specific lung diseases depending on age.", "content": "Relationship between the respiratory and lipopexic function of the lungs in some non-specific lung diseases depending on age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219939"} {"pmid": "4219940", "title": "Changes in glucose regulation following stomach resection according to Billroth II.", "content": "Changes in glucose regulation following stomach resection according to Billroth II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219940"} {"pmid": "4219941", "title": "Changes in cholinesterase activity in white rats, after several injections of TMB-4 and atropine, following treatment with parathion.", "content": "Changes in cholinesterase activity in white rats, after several injections of TMB-4 and atropine, following treatment with parathion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219941"} {"pmid": "4219942", "title": "Development of trichomonas vaginalis upon a medium \"Trimed\" containing serum of various animal origin.", "content": "Development of trichomonas vaginalis upon a medium \"Trimed\" containing serum of various animal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219942"} {"pmid": "4219943", "title": "Juniper bath treatment of the neurasthenic neurosis.", "content": "Juniper bath treatment of the neurasthenic neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219943"} {"pmid": "4219944", "title": "Schemes on the application of BCG to skin cancer.", "content": "Schemes on the application of BCG to skin cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219944"} {"pmid": "4219945", "title": "Radio-active gold as an indicator in the study of the laxative effectiveness of some medicines.", "content": "Radio-active gold as an indicator in the study of the laxative effectiveness of some medicines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219945"} {"pmid": "4219946", "title": "Comparison between the results of the 131I--rose bengal functional examination and the scintigraphia in patients with liver diseases.", "content": "Comparison between the results of the 131I--rose bengal functional examination and the scintigraphia in patients with liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219946"} {"pmid": "4219947", "title": "Congenital lobar emphysema--pathoanatomic studies of three cases.", "content": "Congenital lobar emphysema--pathoanatomic studies of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219947"} {"pmid": "4219948", "title": "Forensic medical and forensic chemical study of acute lethal poisinnins with thiodan.", "content": "Forensic medical and forensic chemical study of acute lethal poisinnins with thiodan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219948"} {"pmid": "4219950", "title": "Transepithelial potential difference in toad urinary bladder is not due to ionic diffusion.", "content": "Transepithelial potential difference in toad urinary bladder is not due to ionic diffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219950"} {"pmid": "4219951", "title": "Adjuvant activity in delayed hypersensitivity of the peptidic part of bacterial peptidoglycans.", "content": "Adjuvant activity in delayed hypersensitivity of the peptidic part of bacterial peptidoglycans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219951"} {"pmid": "4219952", "title": "Effects of dietary supplementation on the humoral immune response of malnourished mice.", "content": "Effects of dietary supplementation on the humoral immune response of malnourished mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219952"} {"pmid": "4219957", "title": "Side effects of clonazepam therapy.", "content": "Side effects of clonazepam therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219957"} {"pmid": "4219958", "title": "Hypercalcaemia and epilepsy.", "content": "Hypercalcaemia and epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219958"} {"pmid": "4219959", "title": "Partial status epilepticus with speech arrest.", "content": "Partial status epilepticus with speech arrest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219959"} {"pmid": "4219960", "title": "Neuro-ophthalmic deterioration after burns.", "content": "Neuro-ophthalmic deterioration after burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219960"} {"pmid": "4219962", "title": "Damage to the inner ear in mastoid surgery.", "content": "Damage to the inner ear in mastoid surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219962"} {"pmid": "4219963", "title": "Sex-dependent behavioral effects of cerebral cortical lesions in the developing rhesus monkey.", "content": "Sex-dependent behavioral effects of cerebral cortical lesions in the developing rhesus monkey. Male rhesus monkeys with orbital prefrontal lesions were imtpaired on behavioral tests at 2(1/2) months of age whereas similar deficits were not detected in females with comparable lesions until 15 to 18 months of age. The results suggest that the maturation of a cortical region in the primate brain proceeds at different tempos in males and females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219963"} {"pmid": "4219964", "title": "Size and scaling in human evolution.", "content": "Size and scaling in human evolution. Our general conclusion is simply stated: many lineages display phyletic size increase; allometric changes almost always accompany increase in body size. We cannot judge adaptation until we separate such changes into those required by increasing size and those serving as special adaptations to changing environments. In our view, the three australopithecines are, in a number of features, scaled variants of the \"same\" animal. In these characters, A. africanus is no more \"advanced\" than the larger, more robust forms. The one early hominid to show a significant departure from this adaptive pattern toward later hominids-cranially, dentally, and postcranially-is H. habilis from East Africa. The australopithecines, one of which was probably a precursor of the Homolineage, were apparently a successful group of basically vegetarian hominids, more advanced behaviorally than apes (87), but not hunter-gatherers. The fossil hominids of Africa fall into two major groupings. One probable lineage, the australopithecines, apparently became extinct without issue; the other evolved to modern man. Both groups displayed steady increase in body size. We consider quantitatively two key characters of the hominid skull: cranial capacity and cheek tooth size. The variables are allometrically related to body size in both lineages. In australopithecines, the manner of relative growth neatly meets the predictions for functional equivalence over a wide range of sizes (negative allometry of cranial capacity with a slope against body weight of 0.2 to 0.4 and positive allometry of postcanine area with a slope near 0.75). In the A. africanus to H. sapiens lineage, cranial capacity increases with positive allometry (slope 1.73) while cheek teeth decrease absolutely (slope - 0.725). Clearly, these are special adaptations unrelated to the physical requirements of increasing body size. We examined qualitatively other features, which also seem to vary allometrically. Of course, many characters should be studied quantitatively, but we think that the scheme outlined here should be treated as the null hypothesis to be disproved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219964"} {"pmid": "4219965", "title": "Neural basis of orientation perception in primate vision.", "content": "Neural basis of orientation perception in primate vision. Orientational differences in human visual acuity can be related parametrically to the distribution of optimal orientations for the receptive fields of neurons in the striate cortex of the rhesus monkey. Both behavioral measures of acuity and the distribution of receptive fields exhibit maximums for stimuli horizontal or vertical relative to the retina; the effect diminishes with distance from the fovea. The anisotropy in the neuronal population and in visual acuity appear to be determined by postnatal visual experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219965"} {"pmid": "4219966", "title": "The use of a diphosphonate in para-articular ossifications after total hip replacement. A clinical study.", "content": "The use of a diphosphonate in para-articular ossifications after total hip replacement. A clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219966"} {"pmid": "4219969", "title": "Autoperfusing heart-lung preparation: prolonged survival by extracorporeal symbiosis.", "content": "Autoperfusing heart-lung preparation: prolonged survival by extracorporeal symbiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219969"} {"pmid": "4219972", "title": "The relationship between precursor and mature forms of the 23S ribosomal RNA.", "content": "The relationship between precursor and mature forms of the 23S ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219972"} {"pmid": "4219973", "title": "Comparison of RNA sequences from widely divergent species.", "content": "Comparison of RNA sequences from widely divergent species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219973"} {"pmid": "4219974", "title": "A new isozyme of triose phosphate isomerase specific to hominoids.", "content": "A new isozyme of triose phosphate isomerase specific to hominoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219974"} {"pmid": "4219975", "title": "Doublet frequency analysis of bacterial DNAs.", "content": "Doublet frequency analysis of bacterial DNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219975"} {"pmid": "4219979", "title": "The isolation and identification of an antigen for the diagnosis of bovine mastitis by radial immunodiffusion.", "content": "The isolation and identification of an antigen for the diagnosis of bovine mastitis by radial immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219979"} {"pmid": "4219985", "title": "Vibrations of the temporal bone due to head injury.", "content": "Vibrations of the temporal bone due to head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219985"} {"pmid": "4219986", "title": "A long-term study of children born to diabetic mothers. (With special reference to occurrence of late neurological abnormalities).", "content": "A long-term study of children born to diabetic mothers. (With special reference to occurrence of late neurological abnormalities).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219986"} {"pmid": "4219987", "title": "Parenteral hyperalimentation: a beginning.", "content": "Parenteral hyperalimentation: a beginning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219987"} {"pmid": "4219988", "title": "Intravenous Additive program: progress at Naval Hospital Portsmouth.", "content": "Intravenous Additive program: progress at Naval Hospital Portsmouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219988"} {"pmid": "4219990", "title": "Prostaglandins in nephrology.", "content": "Prostaglandins in nephrology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219990"} {"pmid": "4219989", "title": "Morphology and serum complement levels in membranoproliferative glomerulonephritis.", "content": "Morphology and serum complement levels in membranoproliferative glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219989"} {"pmid": "4219992", "title": "Parathyroid function in renal insufficiency.", "content": "Parathyroid function in renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219992"} {"pmid": "4219993", "title": "Influence of the preservation technique on the early function of the kidney after reimplantation.", "content": "Influence of the preservation technique on the early function of the kidney after reimplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219993"} {"pmid": "4219991", "title": "The functional significance of complement.", "content": "The functional significance of complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219991"} {"pmid": "4219994", "title": "Are there contraindications to renal transplantation?", "content": "Are there contraindications to renal transplantation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219994"} {"pmid": "4219995", "title": "Recent drug management advances in renal insufficiency.", "content": "Recent drug management advances in renal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219995"} {"pmid": "4219997", "title": "The nature and pathogenesis of systemic amyloidosis.", "content": "The nature and pathogenesis of systemic amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219997"} {"pmid": "4219996", "title": "Renal insufficiency in lupus nephritis.", "content": "Renal insufficiency in lupus nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219996"} {"pmid": "4219998", "title": "Complement deposition in the kidney.", "content": "Complement deposition in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219998"} {"pmid": "4219999", "title": "Evidence for activation of the alternate pathway in glomerulonephritis.", "content": "Evidence for activation of the alternate pathway in glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4219999"} {"pmid": "4220000", "title": "Complement and mesangiocapillary glomerulonephritis: the role of complement deficiency in glomerulonephritis.", "content": "Complement and mesangiocapillary glomerulonephritis: the role of complement deficiency in glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220000"} {"pmid": "4220001", "title": "Activation of complement in human nephritis.", "content": "Activation of complement in human nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220001"} {"pmid": "4220002", "title": "The C3 nephritic factor (C3NeF) and the heat labile complement inactivator (HLCI) in chronic hypocomplementemic mesangioproliferative glomerulonephritis.", "content": "The C3 nephritic factor (C3NeF) and the heat labile complement inactivator (HLCI) in chronic hypocomplementemic mesangioproliferative glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220002"} {"pmid": "4220006", "title": "M--craniocarpotarsal dystrophy (whistling face syndrome) in two families.", "content": "M--craniocarpotarsal dystrophy (whistling face syndrome) in two families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220006"} {"pmid": "4220007", "title": "N--variable expressivity in craniocarpotarsal dysplasia.", "content": "N--variable expressivity in craniocarpotarsal dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220007"} {"pmid": "4220008", "title": "S--the whistling-face syndrome: report of a case with a renal anomaly.", "content": "S--the whistling-face syndrome: report of a case with a renal anomaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220008"} {"pmid": "4220009", "title": "The REEDS syndrome.", "content": "The REEDS syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220009"} {"pmid": "4220010", "title": "The Roberts syndrome.", "content": "The Roberts syndrome. The Roberts syndrome appears to follow an autosomal recessive mode of inheritance. The cause of the abnormalities probably exerts its effect prior to the seventh week of gestation and only on a few organ systems undergoing development during this time. The peculiar morphologic features of metaphase chromosomes of the one individual who has been studied extensively are unexplained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220010"} {"pmid": "4220011", "title": "Some bacteriological considerations of soft lens wear.", "content": "Some bacteriological considerations of soft lens wear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220011"} {"pmid": "4220003", "title": "Gonadotropin and prolactin secretion in human pseudocyesis: effect of synthetic luteinizing hormone-releasing hormone (LH-RH) and thyrotropin releasing hormone (TRH)", "content": "Gonadotropin and prolactin secretion in human pseudocyesis: effect of synthetic luteinizing hormone-releasing hormone (LH-RH) and thyrotropin releasing hormone (TRH)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220003"} {"pmid": "4220012", "title": "Biophysical intrapartal fetal monitoring.", "content": "Biophysical intrapartal fetal monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220012"} {"pmid": "4220013", "title": "Neurologic problems in perinatology.", "content": "Neurologic problems in perinatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220013"} {"pmid": "4220017", "title": "Radioimmunoassay of plasma LH in rat: basal levels and effects of synthetic LH-RH.", "content": "Radioimmunoassay of plasma LH in rat: basal levels and effects of synthetic LH-RH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220017"} {"pmid": "4220016", "title": "Gel filtration of thyroxine--binding proteins. Identification of human serum protein fractions separated on Sephadex G 100.", "content": "Gel filtration of thyroxine--binding proteins. Identification of human serum protein fractions separated on Sephadex G 100.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220016"} {"pmid": "4220018", "title": "A correlative study of thyroid mast cells and thyroid function in the rat.", "content": "A correlative study of thyroid mast cells and thyroid function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220018"} {"pmid": "4220019", "title": "Gel filtration of thyroxine--binding proteins. Identification of rat plasma protein fractions separated on Sephadex gels.", "content": "Gel filtration of thyroxine--binding proteins. Identification of rat plasma protein fractions separated on Sephadex gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220019"} {"pmid": "4220020", "title": "Observations on plaque morphology of Pseudomonas pyocynea bacteriophages.", "content": "Observations on plaque morphology of Pseudomonas pyocynea bacteriophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220020"} {"pmid": "4220025", "title": "Pathophysiological role of plasma kinins in malaria.", "content": "Pathophysiological role of plasma kinins in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220025"} {"pmid": "4220027", "title": "[D-cycloserine and germination of Bacillus cereus spores].", "content": "[D-cycloserine and germination of Bacillus cereus spores].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220027"} {"pmid": "4220028", "title": "Presubiculum afferents to the entorhinal area and the Papez circuit.", "content": "Presubiculum afferents to the entorhinal area and the Papez circuit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220028"} {"pmid": "4220029", "title": "Projections of auditory responsive cortex in the squirrel monkey.", "content": "Projections of auditory responsive cortex in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220029"} {"pmid": "4220030", "title": "Interhemispheric communication between extraoccipital visual areas in the monkey.", "content": "Interhemispheric communication between extraoccipital visual areas in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220030"} {"pmid": "4220031", "title": "Certain biochemical correlates of intense serotonin histofluorescence in the brain stem of the neonatal monkey.", "content": "Certain biochemical correlates of intense serotonin histofluorescence in the brain stem of the neonatal monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220031"} {"pmid": "4220032", "title": "Impaired orientation after primate tectal lesions.", "content": "Impaired orientation after primate tectal lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220032"} {"pmid": "4220034", "title": "The role of the institution and the concept of parallel services.", "content": "The role of the institution and the concept of parallel services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220034"} {"pmid": "4220035", "title": "Some issues in manpower for parallel services.", "content": "Some issues in manpower for parallel services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220035"} {"pmid": "4220033", "title": "Immunochemical studies of brain glutamate decarboxylase and GABA-transaminase of six inbred strains of mice.", "content": "Immunochemical studies of brain glutamate decarboxylase and GABA-transaminase of six inbred strains of mice. Six different inbred strains of mice (C57BL/6J, CBA/CaJ, CE/J, DBA/2J, LP/J and RF/J) were compared in terms of specific activities and immunochemical properties of brain L-glutamate decarboxylase (GAD) and gamma-aminobutyrate transaminase (GABA-T), the enzymes responsible for the synthesis and degradation of GABA, respectively. GAD from the brains of the different strains was indistinguishable on the basis of specific activities, double diffusion tests, immunoelectrophoresis and inhibition by antibody. However, microcomplement fixation tests showed GAD from DBA and C57BL mice to be most distinctly different from GAD extracted from the Swiss mouse, from which the original antigen was prepared and that the enzyme from the CE, LP and RF also differed. Similar fixation curves were obtained for the GAD from CBA and Swiss mice. GABA-T from the different strains was indistinguishable on the basis of all the tests employed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220033"} {"pmid": "4220036", "title": "Cost-effective analysis. A quandary for geriatric health care systems.", "content": "Cost-effective analysis. A quandary for geriatric health care systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220036"} {"pmid": "4220037", "title": "Symposium--long-time care: research, policy, and practice. Relocation research and social policy.", "content": "Symposium--long-time care: research, policy, and practice. Relocation research and social policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220037"} {"pmid": "4220038", "title": "Approaches to improving the quality of long-term care for older persons.", "content": "Approaches to improving the quality of long-term care for older persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220038"} {"pmid": "4220042", "title": "Specific granules in human and nonhuman vertebrate cardiocytes.", "content": "Specific granules in human and nonhuman vertebrate cardiocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220042"} {"pmid": "4220041", "title": "Sodium cromoglycate 2 per cent solution in perennial rhinitis: a clinical and histological study.", "content": "Sodium cromoglycate 2 per cent solution in perennial rhinitis: a clinical and histological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220041"} {"pmid": "4220044", "title": "Proceedings: Macroscopic organisation of Ligamenta flava in cercopithercinae.", "content": "Proceedings: Macroscopic organisation of Ligamenta flava in cercopithercinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220044"} {"pmid": "4220045", "title": "Proceedings: Vitamin deficiencies and brain metabolism.", "content": "Proceedings: Vitamin deficiencies and brain metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220045"} {"pmid": "4220046", "title": "Serum diamine oxidase in pregnancy.", "content": "Serum diamine oxidase in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220046"} {"pmid": "4220047", "title": "The significance of dental epithelium in the pathogenesis of periodontal disease.", "content": "The significance of dental epithelium in the pathogenesis of periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220047"} {"pmid": "4220056", "title": "Cutis marmorata telangiectatica congenita.", "content": "Cutis marmorata telangiectatica congenita.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220056"} {"pmid": "4220057", "title": "Acanthosis nigricans and hypovitaminosis A. response to topical vitamin A acid.", "content": "Acanthosis nigricans and hypovitaminosis A. response to topical vitamin A acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220057"} {"pmid": "4220074", "title": "A special tupaia cage for the continuous detection of locomotor activity under the auto- or the self-control of light-darkness rhythms.", "content": "A special tupaia cage for the continuous detection of locomotor activity under the auto- or the self-control of light-darkness rhythms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220074"} {"pmid": "4220076", "title": "Transduction of a streptomycin R-factor from Mycobacterium smegmatis to Mycobacterium tuberculosis H37Rv.", "content": "Transduction of a streptomycin R-factor from Mycobacterium smegmatis to Mycobacterium tuberculosis H37Rv.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220076"} {"pmid": "4220077", "title": "A new case-finding programme in a region of Taiwan.", "content": "A new case-finding programme in a region of Taiwan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220077"} {"pmid": "4220078", "title": "The meaning and structure of species as applied to mycobacteria.", "content": "The meaning and structure of species as applied to mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220078"} {"pmid": "4220079", "title": "A family outbreak of tuberculosis in Bristol in 1973 with two cases of tuberculous meningitis.", "content": "A family outbreak of tuberculosis in Bristol in 1973 with two cases of tuberculous meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220079"} {"pmid": "4220080", "title": "A study in Hong Kong to evaluate the role of pretreatment susceptibility tests in the selection of regimens of chemotherapy for pulmonary tuberculosis--second report. A Hong Kong Tuberculosis Treatment Services/British Medical Research Council Investigation.", "content": "A study in Hong Kong to evaluate the role of pretreatment susceptibility tests in the selection of regimens of chemotherapy for pulmonary tuberculosis--second report. A Hong Kong Tuberculosis Treatment Services/British Medical Research Council Investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220080"} {"pmid": "4220081", "title": "A study of delayed hypersensitivity, lymphocyte transformation and leucocyte migration inhibition by M. xenopi and M. tuberculosis in patients harbouring these organisms.", "content": "A study of delayed hypersensitivity, lymphocyte transformation and leucocyte migration inhibition by M. xenopi and M. tuberculosis in patients harbouring these organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220081"} {"pmid": "4220082", "title": "Comparative trials of British BCG vaccine double strength, and Danish BCG vaccine, with standard strength British BCG vaccine.", "content": "Comparative trials of British BCG vaccine double strength, and Danish BCG vaccine, with standard strength British BCG vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220082"} {"pmid": "4220083", "title": "Mycobacterium gadium sp. nov. a new species of rapid-growing scotochromogenic mycobacteria.", "content": "Mycobacterium gadium sp. nov. a new species of rapid-growing scotochromogenic mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220083"} {"pmid": "4220084", "title": "Congenital anomalies of the lower urinary tract from a radiologic point of view.", "content": "Congenital anomalies of the lower urinary tract from a radiologic point of view. Congenital anomalies of the lower urinary tract are being recognized with greater frequency due to the use of micturating cystourethrography. Many of these malformations present with urinary tract infection. Early diagnosis is important as appropriate treatment may prevent deterioration of renal function. Several illustrative cases are presented, such as posterior urethral valves, diverticula of the urethra, rectourethral fistula, and duplication of the urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220084"} {"pmid": "4220085", "title": "Aspartylglycosaminuria: a gargoyle-like syndrome with autosomal recessive inheritance.", "content": "Aspartylglycosaminuria: a gargoyle-like syndrome with autosomal recessive inheritance. Aspartylglycosaminuria is an autosomal recessive disorder of glycoprotein catabolism, characterized by presence of aspartyglycosamine in the urine, progressive mental retardation, coarse face, impaired speech and motor functions, and signs of involvement of connective tissue and skeleton. In infancy, clinical symptoms are mild or absent. Vacuolized lymphocytes are often found in the blood and bone marrow. The disease appears unusually common in Finland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220085"} {"pmid": "4220087", "title": "Ingestion of asbestos.", "content": "Ingestion of asbestos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220087"} {"pmid": "4220092", "title": "The toxicity of sodium nitroprusside.", "content": "The toxicity of sodium nitroprusside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220092"} {"pmid": "4220098", "title": "Local and systemic subarachnoid toxicity of metrizamide in mice and monkeys.", "content": "Local and systemic subarachnoid toxicity of metrizamide in mice and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220098"} {"pmid": "4220100", "title": "Hycanthone: a review of its experimental chemotherapy, pharmacology and toxicology.", "content": "Hycanthone: a review of its experimental chemotherapy, pharmacology and toxicology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220100"} {"pmid": "4220099", "title": "Chloroplast- and cytoplasm-specific aminoacyl-transfer ribonucleic acid synthetases of Euglena gracilis: separation, characterization and site of synthesis.", "content": "Chloroplast- and cytoplasm-specific aminoacyl-transfer ribonucleic acid synthetases of Euglena gracilis: separation, characterization and site of synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220099"} {"pmid": "4220101", "title": "Retinol-binding proteins.", "content": "Retinol-binding proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220101"} {"pmid": "4220102", "title": "A study of the feeding and social behaviour of the \"Macacus rhesus\" monkey after direct electrical stimulation and telestimulation of different points of the amygdala and the hippocampus.", "content": "A study of the feeding and social behaviour of the \"Macacus rhesus\" monkey after direct electrical stimulation and telestimulation of different points of the amygdala and the hippocampus. We examined first the behavior of a single animal (Macacus Rhesus), partially free to move on a Brady chair, before and after direct electrical stimulation of the amygdala and the hippocampus; then the social behavior of two animals, completely free to move in a large behavioral cage, before and after stimulation, by radio, of the amygdala. Certain ventromedial areas of the amygdala have a short and long term inhibitory effect on feeding and social behavior and the hippocampus has a short and long term facilitating effect on feeding behavior, especially during the after discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220102"} {"pmid": "4220103", "title": "Calcium ions and the function of the contractile proteins of muscle.", "content": "Calcium ions and the function of the contractile proteins of muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220103"} {"pmid": "4220104", "title": "Calcium movements in relation to contraction.", "content": "Calcium movements in relation to contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220104"} {"pmid": "4220107", "title": "Effects of administering cold and warmed tube feedings.", "content": "Effects of administering cold and warmed tube feedings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220107"} {"pmid": "4220108", "title": "A physiological and behavioral approach to understanding the mechanisms of obesity and anorexia.", "content": "A physiological and behavioral approach to understanding the mechanisms of obesity and anorexia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220108"} {"pmid": "4220109", "title": "Critique of \"A physiological and behavioral approach to understanding the mechanisms of obesity and anorexia\".", "content": "Critique of \"A physiological and behavioral approach to understanding the mechanisms of obesity and anorexia\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220109"} {"pmid": "4220112", "title": "The effects of oestrogens on the sexual behaviour of the femal rhesus monkey.", "content": "The effects of oestrogens on the sexual behaviour of the femal rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220112"} {"pmid": "4220105", "title": "Photosensitive epilepsy in Papio papio. Possible role of cerebellar lesions on facilitation of seizure discharges.", "content": "Photosensitive epilepsy in Papio papio. Possible role of cerebellar lesions on facilitation of seizure discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220105"} {"pmid": "4220113", "title": "The effects of oestrogen-treatment of the female on the behaviour of the male rhesus monkey.", "content": "The effects of oestrogen-treatment of the female on the behaviour of the male rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220113"} {"pmid": "4220106", "title": "Progressive seizure recruitment in subhuman primates and effect of cerebellar stimulation upon developed vs. developing amygdaloid seizures.", "content": "Progressive seizure recruitment in subhuman primates and effect of cerebellar stimulation upon developed vs. developing amygdaloid seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220106"} {"pmid": "4220119", "title": "Oral manifestations of von Reclinghausen's disease: report of a case.", "content": "Oral manifestations of von Reclinghausen's disease: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220119"} {"pmid": "4220120", "title": "Pathological problems around the placental separation.", "content": "Pathological problems around the placental separation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220120"} {"pmid": "4220125", "title": "Hodgkin's disease and the non-Hodgkin's lymphomas in childhood.", "content": "Hodgkin's disease and the non-Hodgkin's lymphomas in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220125"} {"pmid": "4220127", "title": "Transfer-factor therapy of malignancy.", "content": "Transfer-factor therapy of malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220127"} {"pmid": "4220126", "title": "The chemical therapy of breast cancer.", "content": "The chemical therapy of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220126"} {"pmid": "4220128", "title": "Comparative histology of the sustentacular organs in the tongues of the mammalia.", "content": "Comparative histology of the sustentacular organs in the tongues of the mammalia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220128"} {"pmid": "4220121", "title": "The expression of inherited metabolic disease in cultured cells.", "content": "The expression of inherited metabolic disease in cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220121"} {"pmid": "4220129", "title": "Use of microtiter and agar-gel diffusion techniques in screening avian serums for influenza A and Myxovirus yucaipa antibodies.", "content": "Use of microtiter and agar-gel diffusion techniques in screening avian serums for influenza A and Myxovirus yucaipa antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220129"} {"pmid": "4220134", "title": "Prosthodontics in Japan 1973-1974.", "content": "Prosthodontics in Japan 1973-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220134"} {"pmid": "4220124", "title": "Characteristics of rat normal mammary epithelial cells and dimethylbenzanthracene-induced mammary adenocarcinoma cells grown in monolayer culture.", "content": "Characteristics of rat normal mammary epithelial cells and dimethylbenzanthracene-induced mammary adenocarcinoma cells grown in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220124"} {"pmid": "4220135", "title": "Oral surgery in Japan 1973-1974.", "content": "Oral surgery in Japan 1973-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220135"} {"pmid": "4220137", "title": "Pressure-volume curves and closing volume.", "content": "Pressure-volume curves and closing volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220137"} {"pmid": "4220141", "title": "The rotation of the maxilla.", "content": "The rotation of the maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220141"} {"pmid": "4220142", "title": "Long term observation on the extraction of second permanent molars.", "content": "Long term observation on the extraction of second permanent molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220142"} {"pmid": "4220143", "title": "Milk hygiene and bacteriology in the Sudan: isolation of brucella abortus from cow's milk.", "content": "Milk hygiene and bacteriology in the Sudan: isolation of brucella abortus from cow's milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220143"} {"pmid": "4220144", "title": "Testing acaricide susceptibility of the brown dog tick Rhipicephalus sanguineus (Latreille, 1806). II Teabag method.", "content": "Testing acaricide susceptibility of the brown dog tick Rhipicephalus sanguineus (Latreille, 1806). II Teabag method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220144"} {"pmid": "4220145", "title": "A comparative study of vestibulocortical projection.", "content": "A comparative study of vestibulocortical projection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220145"} {"pmid": "4220146", "title": "The vestibular sensory cells and their innervation.", "content": "The vestibular sensory cells and their innervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220146"} {"pmid": "4220147", "title": "Response patterns of vestibular thalamic neurons in the rhesus monkey.", "content": "Response patterns of vestibular thalamic neurons in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220147"} {"pmid": "4220148", "title": "Effects of labyrinthectomy on optokinetic nystagmus (OKN) and optokinetic after-nystagmus (OKAN).", "content": "Effects of labyrinthectomy on optokinetic nystagmus (OKN) and optokinetic after-nystagmus (OKAN). OKN and OKAN were affected by unilateral and bilateral labyrinthectomy. The maximum velocity of slow phases of OKN induced by drum rotations above 60-75 degrees/sec in either direction was lower after unilateral and bilateral labyrinthectomy. The frequency of OKN was also decreased, and the total deviation of the eyes was reduced for OKN induced by these drum speeds. Changes in OKN eventually recovered. OKAN was reduced in duration after unilateral labyrinthectomy, being initially shorter to the ipsilateral than to the contralateral side. OKAN could no longer be evoked after bilateral labyrinthectomy. This loss was permanent. These data demonstrate the importance of the vestibular system in maintenance of OKN and OKAN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220148"} {"pmid": "4220154", "title": "Experimental study on abnormal habits and malocclusion (part III).", "content": "Experimental study on abnormal habits and malocclusion (part III).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220154"} {"pmid": "4220157", "title": "Non-hormonal methods of antenatal monitoring.", "content": "Non-hormonal methods of antenatal monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220157"} {"pmid": "4220158", "title": "Fetal acid-base balance.", "content": "Fetal acid-base balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220158"} {"pmid": "4220159", "title": "The functional occlusion of the teeth of the Vervet monkey.", "content": "The functional occlusion of the teeth of the Vervet monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220159"} {"pmid": "4220160", "title": "Combination of triamcinolone acetonide and demethylchlortetracycline hydrochloride in the management of pulp hyperemia and acute serous pulpitis.", "content": "Combination of triamcinolone acetonide and demethylchlortetracycline hydrochloride in the management of pulp hyperemia and acute serous pulpitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220160"} {"pmid": "4220171", "title": "Investment bonds for profit.", "content": "Investment bonds for profit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220171"} {"pmid": "4220189", "title": "The healing of extraction wound in the presence of retained root remnants. Clinical, radiographical and histological study.", "content": "The healing of extraction wound in the presence of retained root remnants. Clinical, radiographical and histological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220189"} {"pmid": "4220212", "title": "Epidemiology of Chagas' disease in the state of Ceará, Brazil. IV. The role of dogs and cats as domestic reservoir.", "content": "Epidemiology of Chagas' disease in the state of Ceará, Brazil. IV. The role of dogs and cats as domestic reservoir.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220212"} {"pmid": "4220221", "title": "The need for a national policy for the management of inherited metabolic disease.", "content": "The need for a national policy for the management of inherited metabolic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220221"} {"pmid": "4220224", "title": "Focal seizures, early veins, and increased flow. A clinical, angiographic, and radioisotopic correlation.", "content": "Focal seizures, early veins, and increased flow. A clinical, angiographic, and radioisotopic correlation. Prominent early draining veins have been found in angiograms of four patients studied during an acute benign illness characterized by repetitive focal motor seizures and prominent postictal neurologic deficits. Concomitant intravenous radionuclide gamma camera flow and static images showed increased relative perfusion with a slight positive static uptake on the involved side. Follow-up studies showed no evidence of these abnormalities. These angiographic and radioisotopic findings probably correlate with the clinically observed cortical hyperemia as part of, or subsequent to, focal motor seizures. Alternatively, these findings suggest the possibility that vascular occlusions may be the underlying cause of the patients' illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220224"} {"pmid": "4220222", "title": "Inborn errors of metabolism. Vitamin-responsive genetic disease.", "content": "Inborn errors of metabolism. Vitamin-responsive genetic disease. The several ways in which vitamin administration may bring about a biochemical response in genetic abnormalities have been discussed. Two major interrelated lessons emerge from what we now know about vitamin-responsive genetic disease. First, it is possible to enhance metabolite flow through partially deficient reactions by suitable manipulation of the environment in which a fixed amount of enzyme functions or by changing the concentration of the enzyme itself. The latter approach may be the most versatile in the long run since there may be agents other than vitamins which increase enzyme concentrations. A striking example of such an effect in mammals is furnished by the work of Pitot and his collaborators, who by administration of casein hydrolysate to rats, increased threonine dehydratase activity several hundred-fold (Peraino and Pitot, 1964) by increasing the rate of enzyme synthesis (Jost, Khairallah, and Pitot, 1968). Other means of enhancing enzyme activities, ranging from tissue transplantation to transfer of genetic material, have been discussed elsewhere (for example, see Brady, 1973). These procedures will not be discussed here, other than to mention a recent report (Mukherjee and Krasner, 1973) who transferred several small plugs of liver tissue (approximately 5% of the liver) from normal rats to the livers of rats genetically deficient in bilirubin uridine diphosphate glucuronyltransferase activity. Twelve weeks later the specific activity of glucuronyltransferase had risen in the livers of the recipient rats to 6-23% of normal, and the serum bilirubin of these rats, which had initially been elevated, had fallen to close to, or within, the normal range. Thus liver grafts between suitably matched individuals, may in the near future, become a means of increasing hepatic activities of deficient enzymes to extents which are therapeutically meaningful. The second lesson to be learned from the review presented here is that enhancement of enzyme activity may be therapeutically beneficial even though the increase is small and the activity attained is still reduced relative to normal. It will be well to bear this in mind in any attempts to treat inborn errors of metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220222"} {"pmid": "4220226", "title": "Research support for diagnostic ultrasound.", "content": "Research support for diagnostic ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220226"} {"pmid": "4220225", "title": "Lafora's disease: peroxisomal storage in skeletal muscle.", "content": "Lafora's disease: peroxisomal storage in skeletal muscle. A 17-year-old patient had myoclonic epilepsy caused by Lafora's disease. Biopsy showed polysaccharide accumulations within membrane-bound spaces in skeletal muscle cells. Some of the accumulations were morphologically similar to Lafora bodies as they have been seen in the brain. The histochemical reactions of these membrane-bound spaces suggested that they were peroxisomes. Polysaccharide accumulations also were demonstrated in hepatic cells, where they probably were located in the endoplasmic reticulum. Lafora's disease can be diagnosed by histochemical and electron microscopic study of skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220225"} {"pmid": "4220219", "title": "The localized vasomotor and permeability changes at the site of injury which determine the secondary development of permanent damage: the physical approach (cord cooling).", "content": "The localized vasomotor and permeability changes at the site of injury which determine the secondary development of permanent damage: the physical approach (cord cooling).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220219"} {"pmid": "4220227", "title": "Ultrasound in the diagnosis of hydronephrosis in infants and children.", "content": "Ultrasound in the diagnosis of hydronephrosis in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220227"} {"pmid": "4220228", "title": "The sign of the vena cava: echotomographic illustration of right cardiac insufficiency.", "content": "The sign of the vena cava: echotomographic illustration of right cardiac insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220228"} {"pmid": "4220220", "title": "Resuscitation and parenteral nutrition in patients with acute spinal cord injuries and associated injuries.", "content": "Resuscitation and parenteral nutrition in patients with acute spinal cord injuries and associated injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220220"} {"pmid": "4220229", "title": "Quantitative echography--the basis of tissue differentiation.", "content": "Quantitative echography--the basis of tissue differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220229"} {"pmid": "4220230", "title": "Light-emitting diode device for display of numerical data on any ultrasound oscilloscope.", "content": "Light-emitting diode device for display of numerical data on any ultrasound oscilloscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220230"} {"pmid": "4220223", "title": "Mucopolysaccharidoses and mucolipidoses.", "content": "Mucopolysaccharidoses and mucolipidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220223"} {"pmid": "4220218", "title": "The animal experimental model ischemic injuries.", "content": "The animal experimental model ischemic injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220218"} {"pmid": "4220231", "title": "Indications for ultrasonic scanning in abdominal diagnostics.", "content": "Indications for ultrasonic scanning in abdominal diagnostics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220231"} {"pmid": "4220232", "title": "Echocardiographic determinations of dimensions of normal newborns at 5,280 feet elevation.", "content": "Echocardiographic determinations of dimensions of normal newborns at 5,280 feet elevation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220232"} {"pmid": "4220233", "title": "Schlieren study of pulsed ultrasound transmission through human skull.", "content": "Schlieren study of pulsed ultrasound transmission through human skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220233"} {"pmid": "4220234", "title": "Different standards of presentation used in ultrasound articles.", "content": "Different standards of presentation used in ultrasound articles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220234"} {"pmid": "4220235", "title": "Research support for diagnostic ultrasound.", "content": "Research support for diagnostic ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220235"} {"pmid": "4220236", "title": "Echocardiographic diagnosis of calcific stenosis of a stented aortic homograft in the mitral position.", "content": "Echocardiographic diagnosis of calcific stenosis of a stented aortic homograft in the mitral position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220236"} {"pmid": "4220237", "title": "Ultrasonic B-scanning in rhesus incompatibility.", "content": "Ultrasonic B-scanning in rhesus incompatibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220237"} {"pmid": "4220238", "title": "Enhancement of DNA synthesis in neonatal mouse tibial epiphyses after exposure to therapeutic ultrasound.", "content": "Enhancement of DNA synthesis in neonatal mouse tibial epiphyses after exposure to therapeutic ultrasound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220238"} {"pmid": "4220239", "title": "Ultrasound in twin gestation.", "content": "Ultrasound in twin gestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220239"} {"pmid": "4220240", "title": "The validity of structure identification for cross-sectional echocardiography.", "content": "The validity of structure identification for cross-sectional echocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220240"} {"pmid": "4220241", "title": "Transmitted ultrasound for relief of obstruction in ureters and arteries: current status.", "content": "Transmitted ultrasound for relief of obstruction in ureters and arteries: current status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220241"} {"pmid": "4220243", "title": "Ocular neurofibromatosis.", "content": "Ocular neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220243"} {"pmid": "4220242", "title": "Diabetes mellitus in childhood.", "content": "Diabetes mellitus in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220242"} {"pmid": "4220244", "title": "Effect of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis.", "content": "Effect of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220244"} {"pmid": "4220245", "title": "Genetics of atopic allergy and reagin production.", "content": "Genetics of atopic allergy and reagin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220245"} {"pmid": "4220247", "title": "Mutation frequency decline following chemical mutagenesis of Salmonella typhimurium.", "content": "Mutation frequency decline following chemical mutagenesis of Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220247"} {"pmid": "4220246", "title": "Vernal kerato-conjunctivitis: an allergic disease of the eyes of children.", "content": "Vernal kerato-conjunctivitis: an allergic disease of the eyes of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220246"} {"pmid": "4220248", "title": "The genetics and cytology of a mutator factor in Drosophila melanogaster.", "content": "The genetics and cytology of a mutator factor in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220248"} {"pmid": "4220249", "title": "A population approach to the study of repair of genetic radiation damage in mature spermatozoa of Drosophila melanogaster.", "content": "A population approach to the study of repair of genetic radiation damage in mature spermatozoa of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220249"} {"pmid": "4220250", "title": "Mesangiocapillary glomerulonephritis and persistent hypocomplementemia.", "content": "Mesangiocapillary glomerulonephritis and persistent hypocomplementemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220250"} {"pmid": "4220251", "title": "Delivery of medical care to isolated communities.", "content": "Delivery of medical care to isolated communities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220251"} {"pmid": "4220257", "title": "Virology of germfree rodents.", "content": "Virology of germfree rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220257"} {"pmid": "4220258", "title": "Decreased rate of cytolysis of Colpidium striatum by cystic fibrosis serum. I. Bioassay and evidence for the possible involvement of a C/F factor--IgG complex.", "content": "Decreased rate of cytolysis of Colpidium striatum by cystic fibrosis serum. I. Bioassay and evidence for the possible involvement of a C/F factor--IgG complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220258"} {"pmid": "4220259", "title": "The effect of bovine growth hormone on growth of mammary tumors in hypophysectomized rats.", "content": "The effect of bovine growth hormone on growth of mammary tumors in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220259"} {"pmid": "4220260", "title": "Antibody production to choline acetyltransferase purified from human brain.", "content": "Antibody production to choline acetyltransferase purified from human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220260"} {"pmid": "4220261", "title": "Evolution of enzyme replacement therapy for lipid storage diseases.", "content": "Evolution of enzyme replacement therapy for lipid storage diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220261"} {"pmid": "4220262", "title": "Association of diamine oxidase with microsomal membranes in rabbit liver.", "content": "Association of diamine oxidase with microsomal membranes in rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220262"} {"pmid": "4220263", "title": "Segmental intramural diverticulosis associated with and confined to a spastic area of muscular hypertrophy in a columnar lined oesophagus.", "content": "Segmental intramural diverticulosis associated with and confined to a spastic area of muscular hypertrophy in a columnar lined oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220263"} {"pmid": "4220264", "title": "A study of serum nerve growth stimulating activity in patients with neurofibromatosis utilizing a modified bioassay technique.", "content": "A study of serum nerve growth stimulating activity in patients with neurofibromatosis utilizing a modified bioassay technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220264"} {"pmid": "4220265", "title": "Anemia and neutropenia caused by copper deficiency.", "content": "Anemia and neutropenia caused by copper deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220265"} {"pmid": "4220266", "title": "Hypersensitivity pneumonitis caused by a contaminated cool-mist vaporizer.", "content": "Hypersensitivity pneumonitis caused by a contaminated cool-mist vaporizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220266"} {"pmid": "4220267", "title": "Specificity and molecular features of an insect attractant in a Drosophila mutant.", "content": "Specificity and molecular features of an insect attractant in a Drosophila mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220267"} {"pmid": "4220269", "title": "Genetic transfer of the stable L form state to intact bacterial cells.", "content": "Genetic transfer of the stable L form state to intact bacterial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220269"} {"pmid": "4220270", "title": "A family with two siblings affected by Morquio syndrome (MPS IV). Electrophysiological and psychophysical findings in the visual system.", "content": "A family with two siblings affected by Morquio syndrome (MPS IV). Electrophysiological and psychophysical findings in the visual system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220270"} {"pmid": "4220271", "title": "Myasthenic response to muscle relaxants in von Recklinghausen's disease.", "content": "Myasthenic response to muscle relaxants in von Recklinghausen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220271"} {"pmid": "4220272", "title": "Vertigo.", "content": "Vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220272"} {"pmid": "4220273", "title": "Drug treatment of Menière's disease.", "content": "Drug treatment of Menière's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220273"} {"pmid": "4220274", "title": "Labyrinthine surgery for Menière's disease.", "content": "Labyrinthine surgery for Menière's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220274"} {"pmid": "4220275", "title": "Vestibular neuronitis.", "content": "Vestibular neuronitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220275"} {"pmid": "4220276", "title": "Evaluation of post-traumatic vertigo.", "content": "Evaluation of post-traumatic vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220276"} {"pmid": "4220277", "title": "Positional vertigo and nystagmus.", "content": "Positional vertigo and nystagmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220277"} {"pmid": "4220278", "title": "The diagnosis and evaluation of acoustic neuromas.", "content": "The diagnosis and evaluation of acoustic neuromas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220278"} {"pmid": "4220279", "title": "Labyrinthine tap as a diagnostic test for acoustic neurinoma.", "content": "Labyrinthine tap as a diagnostic test for acoustic neurinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220279"} {"pmid": "4220280", "title": "Surgery of acoustic tumors.", "content": "Surgery of acoustic tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220280"} {"pmid": "4220281", "title": "Menière's disease. Etiology, natural history, and results of treatment.", "content": "Menière's disease. Etiology, natural history, and results of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220281"} {"pmid": "4220282", "title": "Central vertigo.", "content": "Central vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220282"} {"pmid": "4220283", "title": "Basilar-vertebral artery insufficiency as a cause of vertigo.", "content": "Basilar-vertebral artery insufficiency as a cause of vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220283"} {"pmid": "4220284", "title": "Diagnostic evaluation of the patient presenting with vertigo.", "content": "Diagnostic evaluation of the patient presenting with vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220284"} {"pmid": "4220285", "title": "The antimotion sickness drugs.", "content": "The antimotion sickness drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220285"} {"pmid": "4220286", "title": "Basic audiometric findings in Menière's disease.", "content": "Basic audiometric findings in Menière's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220286"} {"pmid": "4220287", "title": "Audiologic tests in the differential diagnosis of vertigo.", "content": "Audiologic tests in the differential diagnosis of vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220287"} {"pmid": "4220288", "title": "The caloric test and its value in evaluation of the patient with vertigo.", "content": "The caloric test and its value in evaluation of the patient with vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220288"} {"pmid": "4220289", "title": "Electronystagmography and its value in the diagnosis of vertigo.", "content": "Electronystagmography and its value in the diagnosis of vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220289"} {"pmid": "4220290", "title": "Appropriate standard of care.", "content": "Appropriate standard of care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220290"} {"pmid": "4220291", "title": "Breakdown of HB 129, HB 130.", "content": "Breakdown of HB 129, HB 130.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220291"} {"pmid": "4220292", "title": "Rx for professional nursing: the Irvis Report.", "content": "Rx for professional nursing: the Irvis Report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220292"} {"pmid": "4220293", "title": "Cost control in the delivery of health care services.", "content": "Cost control in the delivery of health care services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220293"} {"pmid": "4220294", "title": "Professional nursing and the abortion decisions.", "content": "Professional nursing and the abortion decisions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220294"} {"pmid": "4220295", "title": "Why nurses leave nursing.", "content": "Why nurses leave nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220295"} {"pmid": "4220296", "title": "Conventional radiography of the temporal bone.", "content": "Conventional radiography of the temporal bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220296"} {"pmid": "4220297", "title": "Tomographic anatomy of the temporal bone.", "content": "Tomographic anatomy of the temporal bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220297"} {"pmid": "4220298", "title": "Tomographic evaluation of cholesteatomas of the middle ear and mastoid.", "content": "Tomographic evaluation of cholesteatomas of the middle ear and mastoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220298"} {"pmid": "4220299", "title": "Otosclerosis.", "content": "Otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220299"} {"pmid": "4220300", "title": "The diagnosis of acoustic neuromas.", "content": "The diagnosis of acoustic neuromas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220300"} {"pmid": "4220301", "title": "Trauma of the ear.", "content": "Trauma of the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220301"} {"pmid": "4220302", "title": "Congenital malformations of the ear.", "content": "Congenital malformations of the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220302"} {"pmid": "4220303", "title": "Normal radiographic anatomy of the paranasal sinuses.", "content": "Normal radiographic anatomy of the paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220303"} {"pmid": "4220304", "title": "Inflammatory diseases of the paranasal sinuses.", "content": "Inflammatory diseases of the paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220304"} {"pmid": "4220305", "title": "Fractures of the paranasal sinuses.", "content": "Fractures of the paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220305"} {"pmid": "4220306", "title": "Cysts, benign tumors, and malignant tumors of the paranasal sinuses.", "content": "Cysts, benign tumors, and malignant tumors of the paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220306"} {"pmid": "4220307", "title": "Sialography and the salivary glands.", "content": "Sialography and the salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220307"} {"pmid": "4220308", "title": "The temporomandibular joint.", "content": "The temporomandibular joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220308"} {"pmid": "4220309", "title": "Radiology of the larynx.", "content": "Radiology of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220309"} {"pmid": "4220310", "title": "Radiological studies of the lymphatic system of the head and neck.", "content": "Radiological studies of the lymphatic system of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220310"} {"pmid": "4220311", "title": "Bronchography.", "content": "Bronchography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220311"} {"pmid": "4220312", "title": "Anatomy of the nasal cavities.", "content": "Anatomy of the nasal cavities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220312"} {"pmid": "4220313", "title": "Physiology of the nose.", "content": "Physiology of the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220313"} {"pmid": "4220314", "title": "Olfaction.", "content": "Olfaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220314"} {"pmid": "4220315", "title": "The nasal vasomotor reaction.", "content": "The nasal vasomotor reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220315"} {"pmid": "4220316", "title": "The \"stuffy\" nose.", "content": "The \"stuffy\" nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220316"} {"pmid": "4220317", "title": "Submucous operations on the nasal septum.", "content": "Submucous operations on the nasal septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220317"} {"pmid": "4220318", "title": "Nasal septoplasty.", "content": "Nasal septoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220318"} {"pmid": "4220319", "title": "Septal perforations.", "content": "Septal perforations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220319"} {"pmid": "4220321", "title": "Nasal Hemorrhage.", "content": "Nasal Hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220321"} {"pmid": "4220320", "title": "Minor intranasal procedures.", "content": "Minor intranasal procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220320"} {"pmid": "4220322", "title": "Septal dermoplasty for hereditary telangiectasia and other conditions.", "content": "Septal dermoplasty for hereditary telangiectasia and other conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220322"} {"pmid": "4220323", "title": "Cerebrospinal fluid rhinorrhea.", "content": "Cerebrospinal fluid rhinorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220323"} {"pmid": "4220324", "title": "Atrophic rhinitis.", "content": "Atrophic rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220324"} {"pmid": "4220325", "title": "Choanal atresia.", "content": "Choanal atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220325"} {"pmid": "4220326", "title": "Nasal fistulas.", "content": "Nasal fistulas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220326"} {"pmid": "4220327", "title": "Neoplasms of the nasal cavity.", "content": "Neoplasms of the nasal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220327"} {"pmid": "4220328", "title": "Unusual nasal tumors. Problems in diagnosis and treatment.", "content": "Unusual nasal tumors. Problems in diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220328"} {"pmid": "4220329", "title": "Rhinomanometry.", "content": "Rhinomanometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220329"} {"pmid": "4220330", "title": "A public concern--a study of the provision of denture services in the delivery of dental health care in Ontario.", "content": "A public concern--a study of the provision of denture services in the delivery of dental health care in Ontario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220330"} {"pmid": "4220348", "title": "Cholinergic mechanisms in aggressive behaviour.", "content": "Cholinergic mechanisms in aggressive behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220348"} {"pmid": "4220349", "title": "Monohydroxy bile acids in plasma in intrahepatic cholestasis of pregnancy. Identification by computerized gas chromatography-mass spectrometry.", "content": "Monohydroxy bile acids in plasma in intrahepatic cholestasis of pregnancy. Identification by computerized gas chromatography-mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220349"} {"pmid": "4220350", "title": "Effect of ventromedial tegmental lesions on central catecholamine neurons of monkey brain: involvement of dopamine pathways in tremor and involuntary movements.", "content": "Effect of ventromedial tegmental lesions on central catecholamine neurons of monkey brain: involvement of dopamine pathways in tremor and involuntary movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220350"} {"pmid": "4220351", "title": "Energy and protein requirements. Report of a joint FAO/WHO ad hoc expert committee. Rome, 22 March-2 April 1971.", "content": "Energy and protein requirements. Report of a joint FAO/WHO ad hoc expert committee. Rome, 22 March-2 April 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220351"} {"pmid": "4220352", "title": "Toxicological evaluation of some enzymes, modified starches and certain other substances. Joint FAO/WHO Expert Committee on Food Additives.", "content": "Toxicological evaluation of some enzymes, modified starches and certain other substances. Joint FAO/WHO Expert Committee on Food Additives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220352"} {"pmid": "4220353", "title": "Some aspects of prognosis after severe head injury.", "content": "Some aspects of prognosis after severe head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220353"} {"pmid": "4220354", "title": "Rehabilitation in severe head injuries.", "content": "Rehabilitation in severe head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220354"} {"pmid": "4220355", "title": "Controlled ventilation in the management of patients with severe head injuries.", "content": "Controlled ventilation in the management of patients with severe head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220355"} {"pmid": "4220356", "title": "Translational versus rotational acceleration: animal experiments with measured input.", "content": "Translational versus rotational acceleration: animal experiments with measured input.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220356"} {"pmid": "4220357", "title": "Hydrocephalus following traumatic head injuries.", "content": "Hydrocephalus following traumatic head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220357"} {"pmid": "4220358", "title": "Evaluation of mental disturbances after head injury.", "content": "Evaluation of mental disturbances after head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220358"} {"pmid": "4220359", "title": "Cardiac conditioning and extinction in Macaca mulatta during block of the CR by cardiac pacing.", "content": "Cardiac conditioning and extinction in Macaca mulatta during block of the CR by cardiac pacing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220359"} {"pmid": "4220361", "title": "CS intensity effects on rabbit nictitating membrane conditioning, extinction and generalization.", "content": "CS intensity effects on rabbit nictitating membrane conditioning, extinction and generalization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220361"} {"pmid": "4220360", "title": "Psychopharmacologic facilitation of operant conditioning of genetically nervous catahoula and pointer dogs.", "content": "Psychopharmacologic facilitation of operant conditioning of genetically nervous catahoula and pointer dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220360"} {"pmid": "4220365", "title": "The effect of tranylcypromine (parnate) on eyelid conditioning and paired associate learning in depressed patients.", "content": "The effect of tranylcypromine (parnate) on eyelid conditioning and paired associate learning in depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220365"} {"pmid": "4220363", "title": "Procedure for operant conditioning of the dog.", "content": "Procedure for operant conditioning of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220363"} {"pmid": "4220364", "title": "Hypothesis on the significance of RNA-directed DNA synthesis for evolution.", "content": "Hypothesis on the significance of RNA-directed DNA synthesis for evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220364"} {"pmid": "4220367", "title": "The rehabilitation of genetically nervous dogs.", "content": "The rehabilitation of genetically nervous dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220367"} {"pmid": "4220362", "title": "Inability to condition a peripheral activating drug.", "content": "Inability to condition a peripheral activating drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220362"} {"pmid": "4220378", "title": "Altered development of central noradrenaline neurons during ontogeny by 6-hydroxydopamine.", "content": "Altered development of central noradrenaline neurons during ontogeny by 6-hydroxydopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220378"} {"pmid": "4220377", "title": "Studies on the intestinal actions of tyramine.", "content": "Studies on the intestinal actions of tyramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220377"} {"pmid": "4220380", "title": "Observations on the concept of neighbourhood knowledge and the distribution of marriage distances.", "content": "Observations on the concept of neighbourhood knowledge and the distribution of marriage distances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220380"} {"pmid": "4220370", "title": "A group practice approach to sex education.", "content": "A group practice approach to sex education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220370"} {"pmid": "4220379", "title": "Genetic markers in chronic myelocytic leukaemia: evidence opposing autosomal inactivation and favouring 6-PGD-Rh linkage.", "content": "Genetic markers in chronic myelocytic leukaemia: evidence opposing autosomal inactivation and favouring 6-PGD-Rh linkage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220379"} {"pmid": "4220366", "title": "Emotions and cardiac contractility as reflected in ballistocardiographic recordings.", "content": "Emotions and cardiac contractility as reflected in ballistocardiographic recordings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220366"} {"pmid": "4220368", "title": "Long-term conditioned fear modification in the dog as measured by changes in urinary 11-hydroxycorticosteroids, heart rate and behavior.", "content": "Long-term conditioned fear modification in the dog as measured by changes in urinary 11-hydroxycorticosteroids, heart rate and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220368"} {"pmid": "4220384", "title": "Clinical value of nerve conduction studies.", "content": "Clinical value of nerve conduction studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220384"} {"pmid": "4220369", "title": "The effect of change in US quality on the blocking effect.", "content": "The effect of change in US quality on the blocking effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220369"} {"pmid": "4220381", "title": "Studies of the density and the properties of the hair in a new inherited syndrome of hypotrichosis.", "content": "Studies of the density and the properties of the hair in a new inherited syndrome of hypotrichosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220381"} {"pmid": "4220385", "title": "Current trends in infant feeding.", "content": "Current trends in infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220385"} {"pmid": "4220372", "title": "A survey of symptoms occurring in pregnancy.", "content": "A survey of symptoms occurring in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220372"} {"pmid": "4220371", "title": "The probation officer. Part II.", "content": "The probation officer. Part II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220371"} {"pmid": "4220387", "title": "Clinical research in cleft lip and cleft palate: the state of the art.", "content": "Clinical research in cleft lip and cleft palate: the state of the art.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220387"} {"pmid": "4220388", "title": "Paediatric nursing: the crying child.", "content": "Paediatric nursing: the crying child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220388"} {"pmid": "4220389", "title": "Mother's milk and other home foods.", "content": "Mother's milk and other home foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220389"} {"pmid": "4220373", "title": "Vasectomy. Safe, simple and trouble-free.", "content": "Vasectomy. Safe, simple and trouble-free.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220373"} {"pmid": "4220375", "title": "Vasectomy. From a patient's viewpoint.", "content": "Vasectomy. From a patient's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220375"} {"pmid": "4220374", "title": "Vasectomy. Sounding a note of concern.", "content": "Vasectomy. Sounding a note of concern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220374"} {"pmid": "4220376", "title": "The sexual problems of doctors.", "content": "The sexual problems of doctors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220376"} {"pmid": "4220391", "title": "Nutrition programs in state health agencies.", "content": "Nutrition programs in state health agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220391"} {"pmid": "4220395", "title": "Food for the growing brain.", "content": "Food for the growing brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220395"} {"pmid": "4220397", "title": "The evaluation of prison treatment and preventive detention programs: some problems faced by the Patuxent institution.", "content": "The evaluation of prison treatment and preventive detention programs: some problems faced by the Patuxent institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220397"} {"pmid": "4220399", "title": "Variations in hormone concentrations in bovine sera used for tissue culture.", "content": "Variations in hormone concentrations in bovine sera used for tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220399"} {"pmid": "4220398", "title": "Lysinuric protein intolerance.", "content": "Lysinuric protein intolerance. Lysinuric protein intolerance is an autosomal recessive disorder which first appears as failure to thrive, vomiting and diarrhea in the infant after weaning from mother's milk. Later it manifests as failure to grow, muscular weakness and osteopenia associated with aversion to animal protein. Some patients become mentally retarded and have periods of stupor. The disease is characterized by marked lysinuria, and hyperammonemia after protein intake. According to accumulating evidence, the basic defect is deficient transport of diamino acids in the intestine, liver and kidney tubuli. Effective treatment is provided by supplementing protein food with extra arginine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220398"} {"pmid": "4220402", "title": "Building standards for the handicapped.", "content": "Building standards for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220402"} {"pmid": "4220403", "title": "The cause and treatment of low back pain during pregnancy.", "content": "The cause and treatment of low back pain during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220403"} {"pmid": "4220393", "title": "The effect of early feeding on the development of obesity.", "content": "The effect of early feeding on the development of obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220393"} {"pmid": "4220404", "title": "An ounce of prevention: the Division of Dental Health.", "content": "An ounce of prevention: the Division of Dental Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220404"} {"pmid": "4220406", "title": "Maternal dehydroepiandrosterone and estrogen production in late pregnancy.", "content": "Maternal dehydroepiandrosterone and estrogen production in late pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220406"} {"pmid": "4220408", "title": "The haemolytic uraemic syndrome.", "content": "The haemolytic uraemic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220408"} {"pmid": "4220410", "title": "The immediate care of thoracic injuries.", "content": "The immediate care of thoracic injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220410"} {"pmid": "4220409", "title": "Lactic dehydrogenase levels in pernicious anemia.", "content": "Lactic dehydrogenase levels in pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220409"} {"pmid": "4220411", "title": "Primary malignant tumors of the retroperitoneum.", "content": "Primary malignant tumors of the retroperitoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220411"} {"pmid": "4220412", "title": "Progress in medicine--a look ahead.", "content": "Progress in medicine--a look ahead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220412"} {"pmid": "4220413", "title": "Neurologic manifestations of electrical injury.", "content": "Neurologic manifestations of electrical injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220413"} {"pmid": "4220416", "title": "The Hippocratic Treatise Peri diaites oxeon.", "content": "The Hippocratic Treatise Peri diaites oxeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220416"} {"pmid": "4220417", "title": "Dates in the printed editions of the Lilium Medicinae.", "content": "Dates in the printed editions of the Lilium Medicinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220417"} {"pmid": "4220414", "title": "Treatment of allergy in children: a double-blind study.", "content": "Treatment of allergy in children: a double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220414"} {"pmid": "4220425", "title": "Intracellular enzyme changes in post-anoxic rat brain.", "content": "Intracellular enzyme changes in post-anoxic rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220425"} {"pmid": "4220426", "title": "The antigenicity in man of staphlylococcal leucocidin toxoid, with notes on therapeutic immunization in chronic osteomyelits.", "content": "The antigenicity in man of staphlylococcal leucocidin toxoid, with notes on therapeutic immunization in chronic osteomyelits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220426"} {"pmid": "4220427", "title": "A cooling modification to an apparatus for phage typing of Staphylococcus aureus.", "content": "A cooling modification to an apparatus for phage typing of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220427"} {"pmid": "4220428", "title": "Studies on the role of sulfhydryl groups in the biochemical mechanisms of allergic inflammation. 8. Influence of glutathione reductase on reactivation of Arthus-type inflammation by glutathione.", "content": "Studies on the role of sulfhydryl groups in the biochemical mechanisms of allergic inflammation. 8. Influence of glutathione reductase on reactivation of Arthus-type inflammation by glutathione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220428"} {"pmid": "4220431", "title": "Autosomal mosaicism occurring in conjunction with Down's syndrome.", "content": "Autosomal mosaicism occurring in conjunction with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220431"} {"pmid": "4220432", "title": "The sibships posterior to mongoloids.", "content": "The sibships posterior to mongoloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220432"} {"pmid": "4220423", "title": "Cystic acne of infancy.", "content": "Cystic acne of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220423"} {"pmid": "4220424", "title": "Follicular mucinosis (alopecia mucinosa).", "content": "Follicular mucinosis (alopecia mucinosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220424"} {"pmid": "4220439", "title": "\"A little child shall lead them\".", "content": "\"A little child shall lead them\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220439"} {"pmid": "4220440", "title": "The first appointment--a mutual evaluation session.", "content": "The first appointment--a mutual evaluation session.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220440"} {"pmid": "4220441", "title": "An investment for the future.", "content": "An investment for the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220441"} {"pmid": "4220442", "title": "Are you just a dentist?", "content": "Are you just a dentist?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220442"} {"pmid": "4220443", "title": "An evaluation of the efficacy of hydroxyzine (atarax-vistaril) in controlling the behavior of child patients.", "content": "An evaluation of the efficacy of hydroxyzine (atarax-vistaril) in controlling the behavior of child patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220443"} {"pmid": "4220444", "title": "Permanent tooth eruption in children with major physical defect and disease.", "content": "Permanent tooth eruption in children with major physical defect and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220444"} {"pmid": "4220445", "title": "A simplified radiographic technique for the difficult patient.", "content": "A simplified radiographic technique for the difficult patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220445"} {"pmid": "4220446", "title": "The problem of P.T.B. aggravation in compensation cases .", "content": "The problem of P.T.B. aggravation in compensation cases .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220446"} {"pmid": "4220447", "title": "Acne vulgaris.", "content": "Acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220447"} {"pmid": "4220448", "title": "The angiogram and pulmonary artery structure and branching (in the normal and with reference to disease).", "content": "The angiogram and pulmonary artery structure and branching (in the normal and with reference to disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220448"} {"pmid": "4220465", "title": "The skin of primates. XXVI. Specific and nonspecific phosphatases in the skin of the rhesus monkey.", "content": "The skin of primates. XXVI. Specific and nonspecific phosphatases in the skin of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220465"} {"pmid": "4220466", "title": "Plasmin and plasminogen levels in pregnancy.", "content": "Plasmin and plasminogen levels in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220466"} {"pmid": "4220468", "title": "Genetic analysis of T4D phage heterozygotes produced in the presence of 5-fluorodeoxyuridine.", "content": "Genetic analysis of T4D phage heterozygotes produced in the presence of 5-fluorodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220468"} {"pmid": "4220469", "title": "Sickle-cell anaemia in an Indian family in Johore.", "content": "Sickle-cell anaemia in an Indian family in Johore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220469"} {"pmid": "4220470", "title": "Haemoglobin E--thalassaemia in Kelantan.", "content": "Haemoglobin E--thalassaemia in Kelantan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220470"} {"pmid": "4220471", "title": "Agglutinins in normal sera for the typhoid-paratyphoid group of organism.", "content": "Agglutinins in normal sera for the typhoid-paratyphoid group of organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220471"} {"pmid": "4220472", "title": "A review of virus infections of the respiratory tract.", "content": "A review of virus infections of the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220472"} {"pmid": "4220473", "title": "The clinical features, management and treatment of El Tor cholera.", "content": "The clinical features, management and treatment of El Tor cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220473"} {"pmid": "4220474", "title": "Nocardia asteroides in Malaya.", "content": "Nocardia asteroides in Malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220474"} {"pmid": "4220475", "title": "A case of renal tubular rickets with absorption defect of glucose and phosphorus.", "content": "A case of renal tubular rickets with absorption defect of glucose and phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220475"} {"pmid": "4220477", "title": "Sir Richard Brunel Hawes.", "content": "Sir Richard Brunel Hawes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220477"} {"pmid": "4220476", "title": "Interdepartmental Committee on Nutrition for National Defence report. Federation of Malaya nutrition survey September--October 1962.", "content": "Interdepartmental Committee on Nutrition for National Defence report. Federation of Malaya nutrition survey September--October 1962.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220476"} {"pmid": "4220479", "title": "When do we do a breast biopsy?", "content": "When do we do a breast biopsy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220479"} {"pmid": "4220480", "title": "Carcinoma of the cervix in Indian women.", "content": "Carcinoma of the cervix in Indian women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220480"} {"pmid": "4220481", "title": "Practical aspects of blood coagulation.", "content": "Practical aspects of blood coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220481"} {"pmid": "4220482", "title": "Evacuant suppositories in postpartum care.", "content": "Evacuant suppositories in postpartum care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220482"} {"pmid": "4220483", "title": "Neurologic manifestations of injury by ionizing radiation.", "content": "Neurologic manifestations of injury by ionizing radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220483"} {"pmid": "4220484", "title": "Social class and reaction to physical disability.", "content": "Social class and reaction to physical disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220484"} {"pmid": "4220485", "title": "Child development projects.", "content": "Child development projects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220485"} {"pmid": "4220486", "title": "Planning for their future.", "content": "Planning for their future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220486"} {"pmid": "4220487", "title": "The factory day at school.", "content": "The factory day at school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220487"} {"pmid": "4220490", "title": "Delayed ontogenesis in human trisomy syndromes.", "content": "Delayed ontogenesis in human trisomy syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220490"} {"pmid": "4220492", "title": "The cost of public health programs in the Philippines.", "content": "The cost of public health programs in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220492"} {"pmid": "4220493", "title": "An experimental biologic approach to the treatment of neoplastic disease; determination of actinomycin in urine and cultures as an aid to diagnosis and prognosis.", "content": "An experimental biologic approach to the treatment of neoplastic disease; determination of actinomycin in urine and cultures as an aid to diagnosis and prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220493"} {"pmid": "4220494", "title": "Mass screening for diabetes using a skin-surface test.", "content": "Mass screening for diabetes using a skin-surface test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220494"} {"pmid": "4220495", "title": "The role of women physicians in disaster medicine.", "content": "The role of women physicians in disaster medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220495"} {"pmid": "4220496", "title": "Some unusual features in a case of traumatic rupture of the thoracic aorta.", "content": "Some unusual features in a case of traumatic rupture of the thoracic aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220496"} {"pmid": "4220498", "title": "Orthodontic care for children in general practice.", "content": "Orthodontic care for children in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220498"} {"pmid": "4220501", "title": "Reactions to nalidixic acid.", "content": "Reactions to nalidixic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220501"} {"pmid": "4220502", "title": "Barriers in dental practice--architectural and structural.", "content": "Barriers in dental practice--architectural and structural.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220502"} {"pmid": "4220508", "title": "Phage type and antibiotic sensitivity of staphylococci isolated from monkeys and their human handlers.", "content": "Phage type and antibiotic sensitivity of staphylococci isolated from monkeys and their human handlers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220508"} {"pmid": "4220510", "title": "Effect of tetracycline on the composition of sebum in acne vulgaris.", "content": "Effect of tetracycline on the composition of sebum in acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220510"} {"pmid": "4220511", "title": "Pathologic coronary vessels and regional systolic narrowing of the coronary arteries in hypertrophic obstructive cardiomyopathy.", "content": "Pathologic coronary vessels and regional systolic narrowing of the coronary arteries in hypertrophic obstructive cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220511"} {"pmid": "4220512", "title": "Tooth ring analysis in mongolism.", "content": "Tooth ring analysis in mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220512"} {"pmid": "4220513", "title": "Sedation in dentistry for children: narcotic action.", "content": "Sedation in dentistry for children: narcotic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220513"} {"pmid": "4220514", "title": "Cardiomyopathies in children in the tropics.", "content": "Cardiomyopathies in children in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220514"} {"pmid": "4220515", "title": "Fibrinolytic activity and fibrinogen levels in Papuans and New Guineans.", "content": "Fibrinolytic activity and fibrinogen levels in Papuans and New Guineans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220515"} {"pmid": "4220516", "title": "Health survey on a rural Malay population F.L.D.A., Sungai Tekam, Pahang.", "content": "Health survey on a rural Malay population F.L.D.A., Sungai Tekam, Pahang.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220516"} {"pmid": "4220517", "title": "Another periauricular abscess from Sarawak, probably caused by a trematode of the genus Poikilorchis, Fain and Vandepitte.", "content": "Another periauricular abscess from Sarawak, probably caused by a trematode of the genus Poikilorchis, Fain and Vandepitte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220517"} {"pmid": "4220520", "title": "Chondroitin sulfate: inhibition of synthesis by puromycin.", "content": "Chondroitin sulfate: inhibition of synthesis by puromycin. Puromycin reversibly inhibits synthesis of chondroitin sulfate by vertebral chondrocytes from 10-day-old chick embryos. Treatment of these cells with puromycin for 5 hours does not affect viability or capacity to multiply on subsequent release from their matrix. It is suggested that synthesis of this polysaccharide is coupled with that of protein; there may be a feedback control in its synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220520"} {"pmid": "4220522", "title": "Myocardial free nucleotides in cardiac hypertrophy.", "content": "Myocardial free nucleotides in cardiac hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220522"} {"pmid": "4220523", "title": "Adenosinetriphosphatase (ATPase) in the auricular heart muscle in human patients operated upon because of acquired and congenital cardiac defects.", "content": "Adenosinetriphosphatase (ATPase) in the auricular heart muscle in human patients operated upon because of acquired and congenital cardiac defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220523"} {"pmid": "4220524", "title": "Glycoside-sensitive ATPase from Arachis hypogaea.", "content": "Glycoside-sensitive ATPase from Arachis hypogaea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220524"} {"pmid": "4220527", "title": "Acne, today.", "content": "Acne, today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220527"} {"pmid": "4220526", "title": "Treatment of recurrent furunculosis with staphylococcal bacteriophage-lysed vaccine.", "content": "Treatment of recurrent furunculosis with staphylococcal bacteriophage-lysed vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220526"} {"pmid": "4220541", "title": "Contact dermatitis due to poison ivy, oak, and sumac.", "content": "Contact dermatitis due to poison ivy, oak, and sumac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220541"} {"pmid": "4220542", "title": "Chronic heart disease due to obesity.", "content": "Chronic heart disease due to obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220542"} {"pmid": "4220543", "title": "The case of Bill Bum, the burbling bursitic.", "content": "The case of Bill Bum, the burbling bursitic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220543"} {"pmid": "4220544", "title": "Medical care of compensation cases in Indiana.", "content": "Medical care of compensation cases in Indiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220544"} {"pmid": "4220547", "title": "The forgotten patient: medical management of the multiple handicapped retarded.", "content": "The forgotten patient: medical management of the multiple handicapped retarded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220547"} {"pmid": "4220549", "title": "This week's offer.", "content": "This week's offer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220549"} {"pmid": "4220550", "title": "How to drill kids without actually shooting them.", "content": "How to drill kids without actually shooting them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220550"} {"pmid": "4220551", "title": "Management of children under general anesthesia.", "content": "Management of children under general anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220551"} {"pmid": "4220552", "title": "Financial implications of leprosy and tuberculosis control in Thailand.", "content": "Financial implications of leprosy and tuberculosis control in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220552"} {"pmid": "4220553", "title": "Evasion of responsibility by physicians in planning health services.", "content": "Evasion of responsibility by physicians in planning health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220553"} {"pmid": "4220554", "title": "A physiological basis for the surgical management of peptic ulceration.", "content": "A physiological basis for the surgical management of peptic ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220554"} {"pmid": "4220555", "title": "Social reality: a necessary dimension to program.", "content": "Social reality: a necessary dimension to program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220555"} {"pmid": "4220556", "title": "Significant legislation passed during the 1965 session of the Arkansas legislature.", "content": "Significant legislation passed during the 1965 session of the Arkansas legislature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220556"} {"pmid": "4220557", "title": "Placenta accreta.", "content": "Placenta accreta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220557"} {"pmid": "4220558", "title": "Multiple causality in psychiatric illness and personality formation. Experimental causation of deviant behavior.", "content": "Multiple causality in psychiatric illness and personality formation. Experimental causation of deviant behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220558"} {"pmid": "4220559", "title": "Resurgence of syphilis.", "content": "Resurgence of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220559"} {"pmid": "4220561", "title": "Effects of freezing on the stability of staphylococcal phages.", "content": "Effects of freezing on the stability of staphylococcal phages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220561"} {"pmid": "4220563", "title": "Spotlighting advances in special education.", "content": "Spotlighting advances in special education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220563"} {"pmid": "4220562", "title": "Streptomycin sensitization.", "content": "Streptomycin sensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220562"} {"pmid": "4220565", "title": "The relation of acid mucopolysaccharides and sulfhydryl groups to diseased oral mucosa.", "content": "The relation of acid mucopolysaccharides and sulfhydryl groups to diseased oral mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220565"} {"pmid": "4220577", "title": "Functions of the cancer cell.", "content": "Functions of the cancer cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220577"} {"pmid": "4220569", "title": "Fibrinogenolytic dysfibrinogenemias.", "content": "Fibrinogenolytic dysfibrinogenemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220569"} {"pmid": "4220568", "title": "Enzymatic effects of fibrinolysin.", "content": "Enzymatic effects of fibrinolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220568"} {"pmid": "4220570", "title": "Clearance of infused fibrin.", "content": "Clearance of infused fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220570"} {"pmid": "4220586", "title": "On the active principles of croton oil. V. Purification and characterisation of further irritant and cocarcinogenic compounds of the B-group.", "content": "On the active principles of croton oil. V. Purification and characterisation of further irritant and cocarcinogenic compounds of the B-group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220586"} {"pmid": "4220588", "title": "Staphylococcal infection in the mouse. 3. The effect of survival in infected animals on the mouse virulence of staphylococci.", "content": "Staphylococcal infection in the mouse. 3. The effect of survival in infected animals on the mouse virulence of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220588"} {"pmid": "4220590", "title": "Surgical correction of inverted nipples.", "content": "Surgical correction of inverted nipples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220590"} {"pmid": "4220591", "title": "Breast feeding in today's world.", "content": "Breast feeding in today's world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220591"} {"pmid": "4220592", "title": "Mammography in the diagnosis of breast cancer.", "content": "Mammography in the diagnosis of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220592"} {"pmid": "4220593", "title": "Reduction mammaplasty with preservation of nipple-glandular continuity.", "content": "Reduction mammaplasty with preservation of nipple-glandular continuity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220593"} {"pmid": "4220594", "title": "Plastic reconstruction of the small breast.", "content": "Plastic reconstruction of the small breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220594"} {"pmid": "4220595", "title": "Spinal cord compression secondary to metastatic mammary carcinoma.", "content": "Spinal cord compression secondary to metastatic mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220595"} {"pmid": "4220596", "title": "Breast feeding and breast disease.", "content": "Breast feeding and breast disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220596"} {"pmid": "4220597", "title": "Changing patterns in education of women.", "content": "Changing patterns in education of women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220597"} {"pmid": "4220605", "title": "\"In vitro\" biosynthesis of androgens by rat submaxillary glands.", "content": "\"In vitro\" biosynthesis of androgens by rat submaxillary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220605"} {"pmid": "4220606", "title": "Electrocardiographic P wave and atrial weights and volumes.", "content": "Electrocardiographic P wave and atrial weights and volumes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220606"} {"pmid": "4220608", "title": "Electromyographic studies on reflex activity of the intercostal and abdominal muscles in cervical cord lesions.", "content": "Electromyographic studies on reflex activity of the intercostal and abdominal muscles in cervical cord lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220608"} {"pmid": "4220610", "title": "A uronic and sialic acid free chick allantoic mucopolysaccharide sulphate which combines with influenza virus hi-antibody to host material. 1. Purification of the substance.", "content": "A uronic and sialic acid free chick allantoic mucopolysaccharide sulphate which combines with influenza virus hi-antibody to host material. 1. Purification of the substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220610"} {"pmid": "4220611", "title": "Accessory lobe of liver presenting through a congenital deficiency of anterior abdominal wall.", "content": "Accessory lobe of liver presenting through a congenital deficiency of anterior abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220611"} {"pmid": "4220613", "title": "Studies on fibrinogen fractions isolated from human plasma by precipitation with cold ether. I. Plasma kinin formation by the activation of contained plasminogen.", "content": "Studies on fibrinogen fractions isolated from human plasma by precipitation with cold ether. I. Plasma kinin formation by the activation of contained plasminogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220613"} {"pmid": "4220618", "title": "Rupture of the rectus abdominis.", "content": "Rupture of the rectus abdominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220618"} {"pmid": "4220620", "title": "Learning problems of handicapped children.", "content": "Learning problems of handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220620"} {"pmid": "4220622", "title": "The ITPA and Down's syndrome: an exploratory study.", "content": "The ITPA and Down's syndrome: an exploratory study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220622"} {"pmid": "4220623", "title": "Dietary and nutritional problems of crippled children in five rural counties of North Carolina.", "content": "Dietary and nutritional problems of crippled children in five rural counties of North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220623"} {"pmid": "4220625", "title": "Transduction of drug-resistances in Staphylococcus. II. Transduction of chloramphenicol-resistance in both Staphylococcus aureus and Staphylococcus epidermidis by typing phage 80.", "content": "Transduction of drug-resistances in Staphylococcus. II. Transduction of chloramphenicol-resistance in both Staphylococcus aureus and Staphylococcus epidermidis by typing phage 80.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220625"} {"pmid": "4220627", "title": "Acne vulgaris. Review of one hundred cases.", "content": "Acne vulgaris. Review of one hundred cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220627"} {"pmid": "4220628", "title": "Treatment of acne.", "content": "Treatment of acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220628"} {"pmid": "4220629", "title": "Treatment of psoriasis, lichen planus, and seborrheic dermatitis.", "content": "Treatment of psoriasis, lichen planus, and seborrheic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220629"} {"pmid": "4220630", "title": "Treatment of drug eruptions.", "content": "Treatment of drug eruptions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220630"} {"pmid": "4220631", "title": "A model of local fibrinolysis (marked elevation of fibrinolytic activity of blood obtained from vasa efferentia of the uterus).", "content": "A model of local fibrinolysis (marked elevation of fibrinolytic activity of blood obtained from vasa efferentia of the uterus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220631"} {"pmid": "4220632", "title": "The metabolism of dehydroepiandrosterone in various organs of the rat.", "content": "The metabolism of dehydroepiandrosterone in various organs of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220632"} {"pmid": "4220634", "title": "Muscle metabolism as seen in single-twitch experiments.", "content": "Muscle metabolism as seen in single-twitch experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220634"} {"pmid": "4220633", "title": "Studies on testosterone metabolism. IV. Urinary 5-alpha- and beta-androstanediols and testosterone glucuronide from testosterone and dehydrolsoandrosterone sulfate in normal people and hirsute women.", "content": "Studies on testosterone metabolism. IV. Urinary 5-alpha- and beta-androstanediols and testosterone glucuronide from testosterone and dehydrolsoandrosterone sulfate in normal people and hirsute women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220633"} {"pmid": "4220635", "title": "Basic aspects of muscle contraction.", "content": "Basic aspects of muscle contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220635"} {"pmid": "4220638", "title": "Abdominal muscle involvement during the performance of various forms of sit-up exercise. An electromyographic study.", "content": "Abdominal muscle involvement during the performance of various forms of sit-up exercise. An electromyographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220638"} {"pmid": "4220639", "title": "A case of Norwegian scabies.", "content": "A case of Norwegian scabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220639"} {"pmid": "4220640", "title": "Industrial rehabilitation.", "content": "Industrial rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220640"} {"pmid": "4220641", "title": "Staphylococcal \"lysates\" and vaccines.", "content": "Staphylococcal \"lysates\" and vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220641"} {"pmid": "4220642", "title": "Cement dermatitis. II. Clinical aspects.", "content": "Cement dermatitis. II. Clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220642"} {"pmid": "4220643", "title": "Antimony spots.", "content": "Antimony spots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220643"} {"pmid": "4220646", "title": "Effect of injectable iron-dextran on dairy calves and lambs.", "content": "Effect of injectable iron-dextran on dairy calves and lambs. Ten Holstein calves, 10 Jersey calves, 7 single lambs, and one lamb from each of ten sets of twins were injected with an iron-dextran solution shortly after birth. These were paired with an equal number of untreated animals that formed the control groups. Percentage of hemoglobin and body weights were recorded periodically up to 16 weeks of age for the calves and 21 weeks for the lambs. Percentage of hemoglobin in the blood of treated calves was generally higher than that of untreated calves but body weights between groups were not significantly different. In the lambs there was no significant difference in percentage of hemoglobin or body weights between the treated and control groups. The results indicate that under the confined system of management as outlined, there was no advantage in administering iron-dextran to young calves or lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220646"} {"pmid": "4220645", "title": "Serum fractions inhibitory to the growth of Leptospires.", "content": "Serum fractions inhibitory to the growth of Leptospires. It is known that the growth inhibitory substance of animal sera on Leptospires exists in the albumin fraction. Since the globulin fraction obtained from animal sera having growth inhibitory property may support, though variable individually, some degree of leptospiral growth, it may be added, with 5% of pooled rabbit serum, to the medium to be used for the propagation of Leptospires.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220645"} {"pmid": "4220647", "title": "A study of Toxoplasma infection in chickens and cats on a family farm.", "content": "A study of Toxoplasma infection in chickens and cats on a family farm. Presumptive evidence of toxoplasmosis was obtained following histological and serological studies of tissues from chickens and cats kept on a family farm. This was confirmed by transmission of the infection to experimental laboratory animals and back to chickens. The significance of the low grade serological reaction in one of the persons living on the farm was not clear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220647"} {"pmid": "4220648", "title": "Phage patterns of coagulase-positive Staphylococci isolated from dogs.", "content": "Phage patterns of coagulase-positive Staphylococci isolated from dogs. One hundred and thirty-seven coagulase-positive strains of Staphylococcus aureus, isolated from dogs, were tested against three synthetic penicillins (cloxacillin, dicloxacillin, and ampicillin) and also phage typed using bacteriophages which are employed in typing staphylococci isolated from man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220648"} {"pmid": "4220649", "title": "Recommended criteria for cardiac catheterization in patients with aortic valve disease.", "content": "Recommended criteria for cardiac catheterization in patients with aortic valve disease. Criteria for selection of patients with aortic valve disease for cardiac catheterization are described, based on a study of 81 cases. Children with aortic stenosis warrant catheterization at the time when the clinical diagnosis is made, but in adults this examination may be deferred until symptoms appear or left ventricular hypertrophy is recognized. In patients with pure aortic insufficiency catheterization may be deferred until symptoms appear. When severe stenosis and insufficiency co-exist, the valve is usually heavily calcified. Thirty-seven per cent of patients with aortic valve disease have co-existing mitral lesions and these patients are usually women, are fibrillating and, as a rule, have atrial enlargement in contrast to those with aortic valve disease only. On rare occasions, patients with mitral valve disease have clinically silent but angiographically demonstrable aortic insufficiency; therefore, aortography should precede open-heart correction of a mitral lesion so as to detect minor degrees of aortic insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220649"} {"pmid": "4220650", "title": "Epilepsy and the law.", "content": "Epilepsy and the law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220650"} {"pmid": "4220652", "title": "The federal program in the preparation of professional personnel in the education of handicapped children and youth.", "content": "The federal program in the preparation of professional personnel in the education of handicapped children and youth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220652"} {"pmid": "4220651", "title": "Elementary and Secondary Education Act: implications for handicapped children.", "content": "Elementary and Secondary Education Act: implications for handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220651"} {"pmid": "4220653", "title": "The National Defense Education Act and exceptional children.", "content": "The National Defense Education Act and exceptional children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220653"} {"pmid": "4220654", "title": "Research and demonstration program for handicapped children and youth.", "content": "Research and demonstration program for handicapped children and youth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220654"} {"pmid": "4220655", "title": "Shortcomings of grant applications to the handicapped children research program.", "content": "Shortcomings of grant applications to the handicapped children research program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220655"} {"pmid": "4220656", "title": "CEC and legislation--now and in the future.", "content": "CEC and legislation--now and in the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220656"} {"pmid": "4220657", "title": "Clearing house: a significant bill becomes law: the Community Mental Health Centers Act Amendments of 1965.", "content": "Clearing house: a significant bill becomes law: the Community Mental Health Centers Act Amendments of 1965.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220657"} {"pmid": "4220658", "title": "\"Teen Town\"--exclusive community for exceptional children.", "content": "\"Teen Town\"--exclusive community for exceptional children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220658"} {"pmid": "4220686", "title": "Aplastic anemia, histiocytosis and erythrodermia in immunologically deficient children. Probable human runt disease.", "content": "Aplastic anemia, histiocytosis and erythrodermia in immunologically deficient children. Probable human runt disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220686"} {"pmid": "4220687", "title": "Progestin-estrogen combinations in management of acne.", "content": "Progestin-estrogen combinations in management of acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220687"} {"pmid": "4220688", "title": "Intensity of function of structures of the differentiated cell as a determinant of activity of its genetic apparatus.", "content": "Intensity of function of structures of the differentiated cell as a determinant of activity of its genetic apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220688"} {"pmid": "4220692", "title": "Studies on the cornea. IV. Some effects of ouabain on pinocytosis and stromal thickness in the rabbit cornea.", "content": "Studies on the cornea. IV. Some effects of ouabain on pinocytosis and stromal thickness in the rabbit cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220692"} {"pmid": "4220693", "title": "Studies on the fibrinolysis in tumor bearing mice. IV. Mechanism of ascites retention with special reference to plasmin activity of tumor cell origin.", "content": "Studies on the fibrinolysis in tumor bearing mice. IV. Mechanism of ascites retention with special reference to plasmin activity of tumor cell origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220693"} {"pmid": "4220697", "title": "Psychological aspects of physical disability.", "content": "Psychological aspects of physical disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220697"} {"pmid": "4220700", "title": "Disturbances of acid-base equilibrium resulting from salicylism in children.", "content": "Disturbances of acid-base equilibrium resulting from salicylism in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220700"} {"pmid": "4220701", "title": "Summer in Siam. Report of a Smith Kline and French foreign fellowship to Thailand, June to September, 1964.", "content": "Summer in Siam. Report of a Smith Kline and French foreign fellowship to Thailand, June to September, 1964.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220701"} {"pmid": "4220702", "title": "Interference and viral infection in a cell line derived from Burkitt's lymphoma.", "content": "Interference and viral infection in a cell line derived from Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220702"} {"pmid": "4220703", "title": "Permeability of laparotomy sponges to cancer cells.", "content": "Permeability of laparotomy sponges to cancer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220703"} {"pmid": "4220704", "title": "Forty years of pediatrics.", "content": "Forty years of pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220704"} {"pmid": "4220705", "title": "Marriage ... and medicine.", "content": "Marriage ... and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220705"} {"pmid": "4220695", "title": "Conference on criteria for, and evaluation of, orthopedic measures in the management of deformities of rheumatoid arthritis.", "content": "Conference on criteria for, and evaluation of, orthopedic measures in the management of deformities of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220695"} {"pmid": "4220706", "title": "Life-threatening drug eruptions.", "content": "Life-threatening drug eruptions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220706"} {"pmid": "4220707", "title": "Eye disorders in handicapped children.", "content": "Eye disorders in handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220707"} {"pmid": "4220708", "title": "Dr. Alvin E. Buckwold. An appreciation.", "content": "Dr. Alvin E. Buckwold. An appreciation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220708"} {"pmid": "4220711", "title": "Fibrosarcoma of the anterior abdominal wall.", "content": "Fibrosarcoma of the anterior abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220711"} {"pmid": "4220712", "title": "Parental age in Down's syndrome (mongolism).", "content": "Parental age in Down's syndrome (mongolism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220712"} {"pmid": "4220722", "title": "Effect of radiation on nuclear phosphorylation in human malignant tumours.", "content": "Effect of radiation on nuclear phosphorylation in human malignant tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220722"} {"pmid": "4220725", "title": "Managing the disabled patient.", "content": "Managing the disabled patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220725"} {"pmid": "4220726", "title": "Bacterial urease. A comparison of urease production with coagulase of Staphylococci and fibrinolysin of Pseudomonas aeruginosa.", "content": "Bacterial urease. A comparison of urease production with coagulase of Staphylococci and fibrinolysin of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220726"} {"pmid": "4220727", "title": "Incorporation of sulfate-35S, N-acetylglucosamine-1-14C, glucose-1-14C, and galactose-1-14C into calf and beef corneal glycosaminoglycans.", "content": "Incorporation of sulfate-35S, N-acetylglucosamine-1-14C, glucose-1-14C, and galactose-1-14C into calf and beef corneal glycosaminoglycans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220727"} {"pmid": "4220728", "title": "Effects of 'pre-incubation' on the distribution of different enzymes in extracts of Escherichia coli.", "content": "Effects of 'pre-incubation' on the distribution of different enzymes in extracts of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220728"} {"pmid": "4220730", "title": "The participation of calcium, adenosine triphosphate and adenosine triphosphatase in the extrusion of the granule proteins from the polymorphonuclear leucocyte.", "content": "The participation of calcium, adenosine triphosphate and adenosine triphosphatase in the extrusion of the granule proteins from the polymorphonuclear leucocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220730"} {"pmid": "4220731", "title": "Natural F-actin. I. Direct isolation of F-actin from myofibrils and its physico-chemical properties.", "content": "Natural F-actin. I. Direct isolation of F-actin from myofibrils and its physico-chemical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220731"} {"pmid": "4220733", "title": "The R-S ratio in lead V2 in the diagnosis of right ventricular hypertrophy.", "content": "The R-S ratio in lead V2 in the diagnosis of right ventricular hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220733"} {"pmid": "4220732", "title": "Water extrusion in isolated subcellular fractions. IV. Simplified system to study the adenosine triphosphate-dependent reaction.", "content": "Water extrusion in isolated subcellular fractions. IV. Simplified system to study the adenosine triphosphate-dependent reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220732"} {"pmid": "4220734", "title": "Plasma viscosity in mental deficiency and Down's syndrome.", "content": "Plasma viscosity in mental deficiency and Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220734"} {"pmid": "4220735", "title": "Serum seromucoid and acid mucopolysaccharide in malignant neoplastic diseases.", "content": "Serum seromucoid and acid mucopolysaccharide in malignant neoplastic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220735"} {"pmid": "4220743", "title": "Pyloroplasty and vagotomy in treatment of duodenal ulcers--a preliminary report.", "content": "Pyloroplasty and vagotomy in treatment of duodenal ulcers--a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220743"} {"pmid": "4220744", "title": "The real self.", "content": "The real self.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220744"} {"pmid": "4220745", "title": "Glomerulo-nephritis.", "content": "Glomerulo-nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220745"} {"pmid": "4220746", "title": "Preparation for international travel.", "content": "Preparation for international travel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220746"} {"pmid": "4220747", "title": "Let's sell Arkansas to our medical students and interns.", "content": "Let's sell Arkansas to our medical students and interns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220747"} {"pmid": "4220751", "title": "Whose chromosomes to count in mongolism?", "content": "Whose chromosomes to count in mongolism?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220751"} {"pmid": "4220750", "title": "Thyroid disease among children with Down's syndrome (mongolism).", "content": "Thyroid disease among children with Down's syndrome (mongolism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220750"} {"pmid": "4220748", "title": "Attitudes as determinants of behavior.", "content": "Attitudes as determinants of behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220748"} {"pmid": "4220770", "title": "Changing concepts in pedodontics.", "content": "Changing concepts in pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220770"} {"pmid": "4220768", "title": "The dissimilation of glucose and gluconate by Acetobacter xylinum. 1. The origin and the fate of triose phosphate.", "content": "The dissimilation of glucose and gluconate by Acetobacter xylinum. 1. The origin and the fate of triose phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220768"} {"pmid": "4220771", "title": "Training the child dental patient.", "content": "Training the child dental patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220771"} {"pmid": "4220773", "title": "Roentgenological manifestations of systematic diseases in children.", "content": "Roentgenological manifestations of systematic diseases in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220773"} {"pmid": "4220774", "title": "The use of gold foil in dentistry for children.", "content": "The use of gold foil in dentistry for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220774"} {"pmid": "4220775", "title": "This is how to do it.", "content": "This is how to do it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220775"} {"pmid": "4220776", "title": "Conservative dentistry gold in young permanent teeth.", "content": "Conservative dentistry gold in young permanent teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220776"} {"pmid": "4220778", "title": "The physician and postmyocardial infarction invalidism.", "content": "The physician and postmyocardial infarction invalidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220778"} {"pmid": "4220777", "title": "Idiopathic hypoventilation.", "content": "Idiopathic hypoventilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220777"} {"pmid": "4220779", "title": "Dentistry and the under fives.", "content": "Dentistry and the under fives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220779"} {"pmid": "4220780", "title": "Premedicating pedodontic patients.", "content": "Premedicating pedodontic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220780"} {"pmid": "4220769", "title": "Mucopolysaccharides in kidneys of vertebrates of various classes.", "content": "Mucopolysaccharides in kidneys of vertebrates of various classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220769"} {"pmid": "4220782", "title": "Differentiation of leukocytic fibrinolytic enzymes from plasmin by the use of plasmatic proteolytic inhibitors.", "content": "Differentiation of leukocytic fibrinolytic enzymes from plasmin by the use of plasmatic proteolytic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220782"} {"pmid": "4220783", "title": "Some observations on the value of the electrocardiogram in patients with chronic cor pulmonale.", "content": "Some observations on the value of the electrocardiogram in patients with chronic cor pulmonale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220783"} {"pmid": "4220784", "title": "Hematoma of the rectus abdominis muscle complicating anticoagulant therapy.", "content": "Hematoma of the rectus abdominis muscle complicating anticoagulant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220784"} {"pmid": "4220789", "title": "Interdisciplinary classification for the aged.", "content": "Interdisciplinary classification for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220789"} {"pmid": "4220790", "title": "Alterations in fibrinogen, plasminogen, and inhibitors of plasmin with the growth of V2 carcinoma in rabbits.", "content": "Alterations in fibrinogen, plasminogen, and inhibitors of plasmin with the growth of V2 carcinoma in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220790"} {"pmid": "4220791", "title": "Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides.", "content": "Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220791"} {"pmid": "4220793", "title": "Effects of heparin, plasmin, dextran, and low molecular dextran on bioelectrically induced thromboses.", "content": "Effects of heparin, plasmin, dextran, and low molecular dextran on bioelectrically induced thromboses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220793"} {"pmid": "4220794", "title": "Removal of subarachnoid blood by the irrigation method.", "content": "Removal of subarachnoid blood by the irrigation method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220794"} {"pmid": "4220795", "title": "Collagen turnover and reorganization in secondary wounds.", "content": "Collagen turnover and reorganization in secondary wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220795"} {"pmid": "4220796", "title": "Liver dysfunction during protracted hepatic artery infusion of massive doses of fluorinated pyrimidine.", "content": "Liver dysfunction during protracted hepatic artery infusion of massive doses of fluorinated pyrimidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220796"} {"pmid": "4220797", "title": "The noble gas ion laser as a light-knife.", "content": "The noble gas ion laser as a light-knife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220797"} {"pmid": "4220799", "title": "A new phage type of Staphylococcus aureus associated with an outbreak of pemphigoid.", "content": "A new phage type of Staphylococcus aureus associated with an outbreak of pemphigoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220799"} {"pmid": "4220800", "title": "Intracutaneous injection of sebum and comedones. Histological observations.", "content": "Intracutaneous injection of sebum and comedones. Histological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220800"} {"pmid": "4220801", "title": "Fixed drug eruption (phenacetin).", "content": "Fixed drug eruption (phenacetin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220801"} {"pmid": "4220802", "title": "Down's syndrome and chronic myelogenous leukemia.", "content": "Down's syndrome and chronic myelogenous leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220802"} {"pmid": "4220804", "title": "Two interconvertible forms of yeast phosphofructokinase with different sensitivity to endproduct inhibition.", "content": "Two interconvertible forms of yeast phosphofructokinase with different sensitivity to endproduct inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220804"} {"pmid": "4220803", "title": "Role of inorganic phosphate in stimulating the glucose utilization of human red blood cells.", "content": "Role of inorganic phosphate in stimulating the glucose utilization of human red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220803"} {"pmid": "4220805", "title": "Erythema multiforme-like eruption due to sulfa.", "content": "Erythema multiforme-like eruption due to sulfa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220805"} {"pmid": "4220806", "title": "Speaking fundamental frequency (SFF) characteristics of mongoloid girls.", "content": "Speaking fundamental frequency (SFF) characteristics of mongoloid girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220806"} {"pmid": "4220808", "title": "Studies on digitalis. XI. Effects of digitoxin on the development of cardiac hypertrophy in the rat subjected to aortic constriction.", "content": "Studies on digitalis. XI. Effects of digitoxin on the development of cardiac hypertrophy in the rat subjected to aortic constriction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220808"} {"pmid": "4220810", "title": "The release of bound adenosine triphosphatase from isolated bacterial membranes and the properties of the solubilized enzyme.", "content": "The release of bound adenosine triphosphatase from isolated bacterial membranes and the properties of the solubilized enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220810"} {"pmid": "4220811", "title": "The metabolism of steroids by tissue from normal and neoplastic rat breast.", "content": "The metabolism of steroids by tissue from normal and neoplastic rat breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220811"} {"pmid": "4220831", "title": "Interrelationship of human plasma kallikrein and plasmin in inflammation.", "content": "Interrelationship of human plasma kallikrein and plasmin in inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220831"} {"pmid": "4220832", "title": "Effect of hydrocortisone on UDPG-dehydrogenase.", "content": "Effect of hydrocortisone on UDPG-dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220832"} {"pmid": "4220827", "title": "Frog gastric mucosal ATPase.", "content": "Frog gastric mucosal ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220827"} {"pmid": "4220835", "title": "Kinetics of (Na+ + K+)-stimulated ATPase of rabbit kidney microsomes.", "content": "Kinetics of (Na+ + K+)-stimulated ATPase of rabbit kidney microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220835"} {"pmid": "4220829", "title": "Urinary excretion of testosterone in idiopathic hirsuitism.", "content": "Urinary excretion of testosterone in idiopathic hirsuitism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220829"} {"pmid": "4220836", "title": "Structure and properties of the acetone adducts of 1-n-propyl nicotinamide iodide.", "content": "Structure and properties of the acetone adducts of 1-n-propyl nicotinamide iodide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220836"} {"pmid": "4220837", "title": "Titration of mitochondrial adenosinetriphosphatase with desaspidin.", "content": "Titration of mitochondrial adenosinetriphosphatase with desaspidin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220837"} {"pmid": "4220838", "title": "Mercury Resistance of Staphylococcus aureus.", "content": "Mercury Resistance of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220838"} {"pmid": "4220839", "title": "Education for the exceptional child.", "content": "Education for the exceptional child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220839"} {"pmid": "4220840", "title": "Skin problems in the school-age child.", "content": "Skin problems in the school-age child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220840"} {"pmid": "4220828", "title": "Acid mucopolysaccharides in rat skin. An electrophoretic study of dermal and subcutaneous tissue.", "content": "Acid mucopolysaccharides in rat skin. An electrophoretic study of dermal and subcutaneous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220828"} {"pmid": "4220843", "title": "Studies on the isolation and composition of interstitial fluid in swine dentine.", "content": "Studies on the isolation and composition of interstitial fluid in swine dentine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220843"} {"pmid": "4220845", "title": "A study of rose bengal and sulfhydryl reagents on stromal fragments of rabbit and human erythrocytes.", "content": "A study of rose bengal and sulfhydryl reagents on stromal fragments of rabbit and human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220845"} {"pmid": "4220847", "title": "Valedictory address.", "content": "Valedictory address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220847"} {"pmid": "4220848", "title": "Haemorrhagic fever in children in Penang.", "content": "Haemorrhagic fever in children in Penang.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220848"} {"pmid": "4220849", "title": "Types of C. diphtheriae in Kuala Lumpur.", "content": "Types of C. diphtheriae in Kuala Lumpur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220849"} {"pmid": "4220850", "title": "Leucocyte alkaline phosphatase, leucocyte count and haemoglobin level in malayan new-borns and young infants.", "content": "Leucocyte alkaline phosphatase, leucocyte count and haemoglobin level in malayan new-borns and young infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220850"} {"pmid": "4220851", "title": "Steady state analysis of BSP distribution between liver and plasma following single injection in intact dogs.", "content": "Steady state analysis of BSP distribution between liver and plasma following single injection in intact dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220851"} {"pmid": "4220852", "title": "The prepuerin test in pregnancy: report of a trial.", "content": "The prepuerin test in pregnancy: report of a trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220852"} {"pmid": "4220853", "title": "Evaluation of intra uterine contraceptive devices.", "content": "Evaluation of intra uterine contraceptive devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220853"} {"pmid": "4220854", "title": "Surgical induction of labour in modern obstetrics.", "content": "Surgical induction of labour in modern obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220854"} {"pmid": "4220855", "title": "Seminal stains--identification and grouping.", "content": "Seminal stains--identification and grouping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220855"} {"pmid": "4220856", "title": "A note of caution on the use of crystalline bovine albumin as a reference standard in the estimation of serum proteins.", "content": "A note of caution on the use of crystalline bovine albumin as a reference standard in the estimation of serum proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220856"} {"pmid": "4220857", "title": "The importance of ante-natal ABO-Rh-antibody determination.", "content": "The importance of ante-natal ABO-Rh-antibody determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220857"} {"pmid": "4220858", "title": "Patella cubiti.", "content": "Patella cubiti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220858"} {"pmid": "4220859", "title": "Granulomatous peritonitis due to Ascaris eggs.", "content": "Granulomatous peritonitis due to Ascaris eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220859"} {"pmid": "4220860", "title": "Maduromycosis of the forearm in a Bajau native of Sabah.", "content": "Maduromycosis of the forearm in a Bajau native of Sabah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220860"} {"pmid": "4220861", "title": "Chromoblastomycosis of the arm in a Chinese in Sabah.", "content": "Chromoblastomycosis of the arm in a Chinese in Sabah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220861"} {"pmid": "4220862", "title": "A brief review of the diabetes mellitus, heart disease and blood pressure studies.", "content": "A brief review of the diabetes mellitus, heart disease and blood pressure studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220862"} {"pmid": "4220863", "title": "Vitamin C deficiency and connective tissue. 3. Determinations of hexosamine, uronic acid, hydroxyproline and uptake of radiosulfate (35S) in granulation tissue.", "content": "Vitamin C deficiency and connective tissue. 3. Determinations of hexosamine, uronic acid, hydroxyproline and uptake of radiosulfate (35S) in granulation tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220863"} {"pmid": "4220864", "title": "The natural history of ventricular septal defects in infancy.", "content": "The natural history of ventricular septal defects in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220864"} {"pmid": "4220865", "title": "The natural history of pulmonary valvular stenosis. Serial cardiac catheterizations in 21 children.", "content": "The natural history of pulmonary valvular stenosis. Serial cardiac catheterizations in 21 children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220865"} {"pmid": "4220866", "title": "Annulo-aortic ectasia with cystic medial necrosis. Diagnosis and surgical treatment.", "content": "Annulo-aortic ectasia with cystic medial necrosis. Diagnosis and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220866"} {"pmid": "4220867", "title": "Association of pulmonary valvular stenosis and muscular ventricular septal defect. Report of a case in a patient aged 75 years.", "content": "Association of pulmonary valvular stenosis and muscular ventricular septal defect. Report of a case in a patient aged 75 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220867"} {"pmid": "4220869", "title": "Phosphofructokinase activity of blood cells in leukemia.", "content": "Phosphofructokinase activity of blood cells in leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220869"} {"pmid": "4220881", "title": "Federal employment of the mentally and emotionally restored.", "content": "Federal employment of the mentally and emotionally restored.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220881"} {"pmid": "4220885", "title": "Farmer's lung, a new industrial disease.", "content": "Farmer's lung, a new industrial disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220885"} {"pmid": "4220886", "title": "Industrial problems relating to the stratum corneum.", "content": "Industrial problems relating to the stratum corneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220886"} {"pmid": "4220887", "title": "The action of thiol inhibitors on the interaction of F-actin and heavy meromyosin.", "content": "The action of thiol inhibitors on the interaction of F-actin and heavy meromyosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220887"} {"pmid": "4220888", "title": "Alkaptonuria, ochronosis, and low-back pain. A case report.", "content": "Alkaptonuria, ochronosis, and low-back pain. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220888"} {"pmid": "4220895", "title": "The pathology of laser irradiation of the skin and body wall of the mouse.", "content": "The pathology of laser irradiation of the skin and body wall of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220895"} {"pmid": "4220896", "title": "Effects of denervation on normal and dystrophic muscle: DNA and nucleotide enzymes.", "content": "Effects of denervation on normal and dystrophic muscle: DNA and nucleotide enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220896"} {"pmid": "4220897", "title": "Effect of right ventricular hypertrophy on infundibular pressure gradients in dogs.", "content": "Effect of right ventricular hypertrophy on infundibular pressure gradients in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220897"} {"pmid": "4220898", "title": "Activation of thrombolysis by streptokinase in the cat.", "content": "Activation of thrombolysis by streptokinase in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220898"} {"pmid": "4220905", "title": "Care of staff's back.", "content": "Care of staff's back.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220905"} {"pmid": "4220903", "title": "The localization of adenosine triphosphatases in morphologically characterized subcellular fractions of guinea-pig brain.", "content": "The localization of adenosine triphosphatases in morphologically characterized subcellular fractions of guinea-pig brain. 1. The distribution of adenosine triphosphatase was studied in morphologically characterized subcellular fractions of guinea-pig brain. The conditions of homogenization were selected so as to favour the survival of nerve endings as organized structures. 2. A fraction consisting mainly of the external membranes of nerve endings was rich in a ouabain-sensitive Na(+)-K(+)-stimulated adenosine triphosphatase which closely resembled that present in the classical microsomal fraction studied by other workers, but which showed a higher specific activity. 3. A dinitrophenol-stimulated adenosine triphosphatase was located in the nerve-ending mitochondria. 4. The synaptic-vesicle fraction contained a small amount of adenosine triphosphatase that differed in its response to several ions and other compounds from the membrane, myelin and mitochondrial fractions, indicating freedom from contamination by these elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220903"} {"pmid": "4220911", "title": "Neuromuscular transmission in vivo and the actions of decamethonium: a micro-electrode study.", "content": "Neuromuscular transmission in vivo and the actions of decamethonium: a micro-electrode study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220911"} {"pmid": "4220912", "title": "Constituents of a microsomal fraction from the mammalian brain: their solubilization, especially by detergents.", "content": "Constituents of a microsomal fraction from the mammalian brain: their solubilization, especially by detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220912"} {"pmid": "4220913", "title": "Determination of oxo steroids as coloured salts of their Girard derivatives.", "content": "Determination of oxo steroids as coloured salts of their Girard derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220913"} {"pmid": "4220914", "title": "Staphylococcus bacteriophage patterns.", "content": "Staphylococcus bacteriophage patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220914"} {"pmid": "4220918", "title": "Antibodies against the various types of skeletal muscle fibres.", "content": "Antibodies against the various types of skeletal muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220918"} {"pmid": "4220920", "title": "Intractable cardiac failure.", "content": "Intractable cardiac failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220920"} {"pmid": "4220921", "title": "Quantitative study of sensitive and lysogenic bacteria surviving infection of a Staphylococcus by a temperate bacteriophage.", "content": "Quantitative study of sensitive and lysogenic bacteria surviving infection of a Staphylococcus by a temperate bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220921"} {"pmid": "4220922", "title": "Corneal dystrophies associated with abnormalities of mucopolysaccharide metabolism.", "content": "Corneal dystrophies associated with abnormalities of mucopolysaccharide metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220922"} {"pmid": "4220916", "title": "Methods of detecting cancer antigens and antitumor antibody.", "content": "Methods of detecting cancer antigens and antitumor antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220916"} {"pmid": "4220925", "title": "Study of the provision of dental care for handicapped children.", "content": "Study of the provision of dental care for handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220925"} {"pmid": "4220917", "title": "Use of antimetabolites in the study of normal and abnormal cell structure and function.", "content": "Use of antimetabolites in the study of normal and abnormal cell structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220917"} {"pmid": "4220926", "title": "The effects of dental treatment on behavior of handicapped patients.", "content": "The effects of dental treatment on behavior of handicapped patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220926"} {"pmid": "4220923", "title": "Oxidative phosphorylation. Biochemical effects and properties of trialkyltins.", "content": "Oxidative phosphorylation. Biochemical effects and properties of trialkyltins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220923"} {"pmid": "4220927", "title": "Ethnocentrism and attitudes toward the physically disabled.", "content": "Ethnocentrism and attitudes toward the physically disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220927"} {"pmid": "4220928", "title": "Human position sense and sense of effort.", "content": "Human position sense and sense of effort.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220928"} {"pmid": "4220932", "title": "Inhibition of citrate metabolism by sodium fluoroacetate in the perfused rat heart and the effect on phosphofructokinase activity and glucose utilization.", "content": "Inhibition of citrate metabolism by sodium fluoroacetate in the perfused rat heart and the effect on phosphofructokinase activity and glucose utilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220932"} {"pmid": "4220933", "title": "Vectorial aspects of adenosine-triphosphatase activity in erythrocyte membranes.", "content": "Vectorial aspects of adenosine-triphosphatase activity in erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220933"} {"pmid": "4220935", "title": "Studies in immunochemistry. 23. Some observations on the heterogeneity of preparations of human blood-group-specific substances.", "content": "Studies in immunochemistry. 23. Some observations on the heterogeneity of preparations of human blood-group-specific substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220935"} {"pmid": "4220934", "title": "Structural and enzymic aspects of the hydrolysis of adenosine triphosphate by membranes of kidney cortex and erythrocytes.", "content": "Structural and enzymic aspects of the hydrolysis of adenosine triphosphate by membranes of kidney cortex and erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220934"} {"pmid": "4220937", "title": "Cytochemical evaluation of metabolic inhibitors in cell culture.", "content": "Cytochemical evaluation of metabolic inhibitors in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220937"} {"pmid": "4220938", "title": "ATP level and cleavage of sea urchin eggs Strongylocentrotus dröbachiensis (O. F. Müller).", "content": "ATP level and cleavage of sea urchin eggs Strongylocentrotus dröbachiensis (O. F. Müller).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220938"} {"pmid": "4220939", "title": "Rate determining step of the coupled reaction system composed of H-meromyosin-adenosinetriphosphatase and creatine kinase.", "content": "Rate determining step of the coupled reaction system composed of H-meromyosin-adenosinetriphosphatase and creatine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220939"} {"pmid": "4220946", "title": "The introduction and use of eastern drugs in the early middle ages.", "content": "The introduction and use of eastern drugs in the early middle ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220946"} {"pmid": "4220951", "title": "Regulation of glucose uptake by muscle. 7. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, on the concentrations of hexose phosphates, nucleotides and inorganic phosphate in perfused rat heart.", "content": "Regulation of glucose uptake by muscle. 7. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, on the concentrations of hexose phosphates, nucleotides and inorganic phosphate in perfused rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220951"} {"pmid": "4220952", "title": "Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles.", "content": "Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220952"} {"pmid": "4220956", "title": "Chronic disease and employability: the physician's role.", "content": "Chronic disease and employability: the physician's role.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220956"} {"pmid": "4220955", "title": "Alcoholism in industry.", "content": "Alcoholism in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220955"} {"pmid": "4220953", "title": "Scadan lotion--a new preparation in the treatment of seborrhea.", "content": "Scadan lotion--a new preparation in the treatment of seborrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220953"} {"pmid": "4220957", "title": "Epidemiologic data on diseases of female workers in Yugoslavia.", "content": "Epidemiologic data on diseases of female workers in Yugoslavia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220957"} {"pmid": "4220959", "title": "Careers.", "content": "Careers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220959"} {"pmid": "4220958", "title": "Occupational medicine--the modern view.", "content": "Occupational medicine--the modern view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220958"} {"pmid": "4220961", "title": "The pre-steady state of the myosin-adenosine triphosphate system. II. Initial rapid absorption and liberation of hydrogen ion followed by a stopped-flow method.", "content": "The pre-steady state of the myosin-adenosine triphosphate system. II. Initial rapid absorption and liberation of hydrogen ion followed by a stopped-flow method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220961"} {"pmid": "4220960", "title": "The pre-steady state of the myosin-adenosine triphosphate system. I. Initial rapid liberation of inorganic phosphate.", "content": "The pre-steady state of the myosin-adenosine triphosphate system. I. Initial rapid liberation of inorganic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220960"} {"pmid": "4220962", "title": "The pre-steady state of the myosin-adenosine triphosphate system. 3. Properties of the intermediate.", "content": "The pre-steady state of the myosin-adenosine triphosphate system. 3. Properties of the intermediate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220962"} {"pmid": "4220964", "title": "Effect of thermal treatment on the calcium sensitivity of myosin B at low ionic strength.", "content": "Effect of thermal treatment on the calcium sensitivity of myosin B at low ionic strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220964"} {"pmid": "4220963", "title": "ATP-induced contraction of sarcomeres.", "content": "ATP-induced contraction of sarcomeres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220963"} {"pmid": "4220965", "title": "Acute liver injury in ducklings as a result of aflatoxin poisoning.", "content": "Acute liver injury in ducklings as a result of aflatoxin poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220965"} {"pmid": "4220966", "title": "Vitamin C deficiency and connective tissue. II. Determinations of hexosamine, uronic acid and hydroxyproline in guinea pig carcasses.", "content": "Vitamin C deficiency and connective tissue. II. Determinations of hexosamine, uronic acid and hydroxyproline in guinea pig carcasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220966"} {"pmid": "4220954", "title": "Fibrinolytic activity of blood in rheumatic fever.", "content": "Fibrinolytic activity of blood in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220954"} {"pmid": "4220972", "title": "Today's dentistry for today's children.", "content": "Today's dentistry for today's children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220972"} {"pmid": "4220968", "title": "The isolation and properties of epithelial-cell \"ghosts\" from rat small intestine.", "content": "The isolation and properties of epithelial-cell \"ghosts\" from rat small intestine. 1. The preparation of gram quantities of isolated epithelial-cell ;ghosts' from mucosal scrapings of rat small intestine is described. The method involves dispersing the tissue by gentle homogenization in 6% dextran in Krebs-Ringer phosphate, pH7.4, followed by filtration through nylon cloth and sedimentation by low-speed centrifuging. 2. The isolated epithelial-cell ;ghosts' contained all of the DNA, but only 52% of the protein and 53-57% of the RNA of the original homogenate. They contained most of the activity of the following enzymes found in the homogenate: aminopeptidase (71%); alkaline beta-glycerophosphatase (82%); invertase (92%); adenosine triphosphatase (93-116%); acid beta-glycerophosphatase (83%); nonspecific esterase (76%); succinate dehydrogenase (96%). Only small proportions of the total lactate-dehydrogenase (10%) and phosphoglucose-isomerase (2%) activities found in the homogenate were recovered in the isolated cell ;ghosts'. 3. The epithelial-cell ;ghost' preparation did not respire unless cofactors and substrates were added, and did not consume glucose or produce lactic acid from glucose. 4. The effect of varying the composition of the homogenization medium was studied. Concentrations of dextran (mol.wt. 15x10(4)) from 1 to 12%, solutions of dextrans (all at 6%) with mol.wt. varying between 3.6x10(4) and 2x10(6), and a solution of 8% polyethylene glycol (mol.wt. 4000) served equally well for the production of epithelial-cell ;ghosts'. Two of these solutions, however, 12% dextran (mol.wt.15x10(4)) and 6% dextran (mol.wt. 2x10(6)), were too viscous to allow the complete sedimentation of the cell ;ghosts' at low relative centrifugal forces. Omission of either Krebs-Ringer phosphate or dextran from the medium resulted in almost complete cell breakage during the homogenization. 5. The isolated cell ;ghosts' were used as a starting material for subcellular fractionation of rat intestinal mucosa by differential centrifugation. The distributions of protein and succinate-dehydrogenase activity among the fractions were compared with corresponding values in fractions isolated by differential centrifugation of mucosa homogenized in 0.3m-sucrose-5mm-EDTA, pH7.4. The method in which cell ;ghosts' were used as starting material gave a better separation and cleaner fractions than the method in which untreated mucosal scrapings were used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220968"} {"pmid": "4220973", "title": "Incidence of dental anomalies encountered in pedodontics.", "content": "Incidence of dental anomalies encountered in pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220973"} {"pmid": "4220984", "title": "Observations on the inhibition of preparations of porcine plasmin by serum and by urinary trypsin inhibitor (mingin).", "content": "Observations on the inhibition of preparations of porcine plasmin by serum and by urinary trypsin inhibitor (mingin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220984"} {"pmid": "4220987", "title": "Idiopathic prepuberal hypertrophy of the male breast. Histochemical evaluation and relation to gynecomastia and other disorders of the breast.", "content": "Idiopathic prepuberal hypertrophy of the male breast. Histochemical evaluation and relation to gynecomastia and other disorders of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220987"} {"pmid": "4220988", "title": "Effects of freezing on the stability of staphylococcal phages.", "content": "Effects of freezing on the stability of staphylococcal phages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220988"} {"pmid": "4220991", "title": "A study of uterine actn.", "content": "A study of uterine actn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220991"} {"pmid": "4220992", "title": "Intestinal transport of glucose in the silkworm, Bombyx mori L.", "content": "Intestinal transport of glucose in the silkworm, Bombyx mori L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220992"} {"pmid": "4220993", "title": "Effects of metals & reducing agents on the incorporation of amino acids into lens RNA & protein.", "content": "Effects of metals & reducing agents on the incorporation of amino acids into lens RNA & protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220993"} {"pmid": "4220994", "title": "Studies in human malignant tissue. I. Protein synthesis in malignant & normal cervix uteri.", "content": "Studies in human malignant tissue. I. Protein synthesis in malignant & normal cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220994"} {"pmid": "4220995", "title": "Lysophosphatidyl ethanolamine of certain species of mycobacteria.", "content": "Lysophosphatidyl ethanolamine of certain species of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220995"} {"pmid": "4220996", "title": "Carbohydrate metabolism in experimental tuberculosis: hepatic enzymes related to glycogen metabolism & synthesis of glycogen from labelled glucose.", "content": "Carbohydrate metabolism in experimental tuberculosis: hepatic enzymes related to glycogen metabolism & synthesis of glycogen from labelled glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220996"} {"pmid": "4220997", "title": "Pigments of unclassified mycobacteria. I. Nature of pigments in a scotochromogenic strain (P-15) of mycobacteria.", "content": "Pigments of unclassified mycobacteria. I. Nature of pigments in a scotochromogenic strain (P-15) of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220997"} {"pmid": "4220998", "title": "Chromatography of plant lytic enzymes on carboxymethyl cellulose.", "content": "Chromatography of plant lytic enzymes on carboxymethyl cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220998"} {"pmid": "4220999", "title": "Some observations on the properdin system. VI. Preparation and properties of buffalo serum properdin.", "content": "Some observations on the properdin system. VI. Preparation and properties of buffalo serum properdin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4220999"} {"pmid": "4221000", "title": "N and C-terminal amino acids of collagen and its examination for the blocking of terminal amino groups by hexoses.", "content": "N and C-terminal amino acids of collagen and its examination for the blocking of terminal amino groups by hexoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221000"} {"pmid": "4221001", "title": "Aconitate isomerase in sugar cane.", "content": "Aconitate isomerase in sugar cane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221001"} {"pmid": "4221002", "title": "Protein bound hexosamine and hexoses in blood of normal adults and children, and pulmonary tuberculosis patients.", "content": "Protein bound hexosamine and hexoses in blood of normal adults and children, and pulmonary tuberculosis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221002"} {"pmid": "4221003", "title": "Occurrence of acid-soluble and acid-insoluble polyphosphates in rabbit liver.", "content": "Occurrence of acid-soluble and acid-insoluble polyphosphates in rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221003"} {"pmid": "4221004", "title": "Action of tetanus toxin on brain and liver mitochondria of resistant and susceptible animals.", "content": "Action of tetanus toxin on brain and liver mitochondria of resistant and susceptible animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221004"} {"pmid": "4221006", "title": "Microbiological transformations of terpenes. V. Origin of 2-nonene, 2,3-dicarboxylic acid anhydride in the fermentation of terpenoid hydrocarbons by Aspergillus niger.", "content": "Microbiological transformations of terpenes. V. Origin of 2-nonene, 2,3-dicarboxylic acid anhydride in the fermentation of terpenoid hydrocarbons by Aspergillus niger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221006"} {"pmid": "4221005", "title": "Metabolic activity of starch granules from the tapioca plant. II. Functional activity of starch granules from tuber.", "content": "Metabolic activity of starch granules from the tapioca plant. II. Functional activity of starch granules from tuber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221005"} {"pmid": "4221007", "title": "Effect of some chemical modifications on the biological activity of catalase.", "content": "Effect of some chemical modifications on the biological activity of catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221007"} {"pmid": "4221008", "title": "Effect of protein depletion on ribonucleic acid metabolism in rat liver.", "content": "Effect of protein depletion on ribonucleic acid metabolism in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221008"} {"pmid": "4221009", "title": "Role of vitamin A in sulphate metabolism. I. Studies on sulphate incorporation into mucopolysaccharides in vitamin A deficient rats.", "content": "Role of vitamin A in sulphate metabolism. I. Studies on sulphate incorporation into mucopolysaccharides in vitamin A deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221009"} {"pmid": "4221010", "title": "Effect of insulin on the resynthesis of glycogen in cerebral cortical slices.", "content": "Effect of insulin on the resynthesis of glycogen in cerebral cortical slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221010"} {"pmid": "4221011", "title": "Vitamin B12 & 14C incorporation into cell proteins of Escherichia coli 113-3. I. Incorporation studies with resting cells.", "content": "Vitamin B12 & 14C incorporation into cell proteins of Escherichia coli 113-3. I. Incorporation studies with resting cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221011"} {"pmid": "4221012", "title": "Spontaneous rupture of the rectus abdominis muscle.", "content": "Spontaneous rupture of the rectus abdominis muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221012"} {"pmid": "4221013", "title": "Fractionation of mycoplasma cells for enzyme localization.", "content": "Fractionation of mycoplasma cells for enzyme localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221013"} {"pmid": "4221018", "title": "Respiratory control by an adenosine triphosphatase involved in active transport in brain cortex.", "content": "Respiratory control by an adenosine triphosphatase involved in active transport in brain cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221018"} {"pmid": "4221019", "title": "The regulation of kidney respiration by sodium and potassium ions.", "content": "The regulation of kidney respiration by sodium and potassium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221019"} {"pmid": "4221020", "title": "Identification of active phosphoprotein in a cation-activated adenosine triphosphatase.", "content": "Identification of active phosphoprotein in a cation-activated adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221020"} {"pmid": "4221021", "title": "Urocanic acid in keratinizing tissue.", "content": "Urocanic acid in keratinizing tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221021"} {"pmid": "4221022", "title": "Characteristics of the ATP-ase activity of isolated neurons of rabbit.", "content": "Characteristics of the ATP-ase activity of isolated neurons of rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221022"} {"pmid": "4221026", "title": "A rapid pH-stat assay for phosphofructokinase and the forward reaction of phosphoglucose isomerase.", "content": "A rapid pH-stat assay for phosphofructokinase and the forward reaction of phosphoglucose isomerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221026"} {"pmid": "4221027", "title": "Adenosine triphosphatase activity in the rod outer segments of the pig retina.", "content": "Adenosine triphosphatase activity in the rod outer segments of the pig retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221027"} {"pmid": "4221029", "title": "Catalysis in reactions of 1-benzyl-1,4-dihydronicotinamide.", "content": "Catalysis in reactions of 1-benzyl-1,4-dihydronicotinamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221029"} {"pmid": "4221028", "title": "Enzymatic sulfation of steroids by bovine tissues.", "content": "Enzymatic sulfation of steroids by bovine tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221028"} {"pmid": "4221030", "title": "Purification, crystallization and properties of activated sheep heart phosphofructokinase.", "content": "Purification, crystallization and properties of activated sheep heart phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221030"} {"pmid": "4221031", "title": "Highly specific sodium-potassium-activated adenosine triphosphatase from various tissues of rabbit.", "content": "Highly specific sodium-potassium-activated adenosine triphosphatase from various tissues of rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221031"} {"pmid": "4221033", "title": "Taming the monster in the chair.", "content": "Taming the monster in the chair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221033"} {"pmid": "4221032", "title": "Some acyl phosphate-like properties of P32-labeled sodium-potassium-activated adenosine triphosphatase.", "content": "Some acyl phosphate-like properties of P32-labeled sodium-potassium-activated adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221032"} {"pmid": "4221034", "title": "The localization of myofibrillar ATPase activity in the flight muscles of the blowfly, Calliphora erythrocephala.", "content": "The localization of myofibrillar ATPase activity in the flight muscles of the blowfly, Calliphora erythrocephala. The distribution of ATPase activity in the asynchronous flight muscles of Calliphora erythrocephala (Diptera) was studied at a fine structural level, using preparations of teased fibers, both unfixed and after brief fixation in hydroxyadipaldehyde, incubated in a medium for the histochemical demonstration of myosin or actomyosin ATPase. In relaxed fibrils, activity was found confined to the A bands and was absent from the H zones as well as from the Z and I band regions. At high magnification, deposits of final product, lead phosphate, appeared primarily related to the thick filaments, or to short lateral extensions from them. Evidence was gathered which indicated that this enzyme activity was that of a triphosphatase which did not act on dinucleoside or non-nucleoside substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221034"} {"pmid": "4221035", "title": "The effect of UV-radiation on HeLa cells infected with adenovirus.", "content": "The effect of UV-radiation on HeLa cells infected with adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221035"} {"pmid": "4221037", "title": "Familiarity, dogmatism, and reported student attitudes toward the disabled.", "content": "Familiarity, dogmatism, and reported student attitudes toward the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221037"} {"pmid": "4221036", "title": "Sodium, potassium-requiring adenosinetriphosphatase activity. II. Mechanism of inhibition by sulphydryl reagents.", "content": "Sodium, potassium-requiring adenosinetriphosphatase activity. II. Mechanism of inhibition by sulphydryl reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221036"} {"pmid": "4221040", "title": "On the presence of mucopolysaccharide material in the labyrinthine epithelium of chick embryo in the first moments of morphogenesis.", "content": "On the presence of mucopolysaccharide material in the labyrinthine epithelium of chick embryo in the first moments of morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221040"} {"pmid": "4221043", "title": "Steroid metabolism in the syndrome of testicular feminization.", "content": "Steroid metabolism in the syndrome of testicular feminization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221043"} {"pmid": "4221044", "title": "Feminizing adrenal tumor in a six-year-old boy.", "content": "Feminizing adrenal tumor in a six-year-old boy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221044"} {"pmid": "4221045", "title": "Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). H. bandicota sp. n. from bandicoot rats in Taiwan, Thailand, and Burma.", "content": "Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). H. bandicota sp. n. from bandicoot rats in Taiwan, Thailand, and Burma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221045"} {"pmid": "4221047", "title": "The effects of fibrinolysin upon tendon healing in the dog.", "content": "The effects of fibrinolysin upon tendon healing in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221047"} {"pmid": "4221049", "title": "Clinical studies on the cardiac performance by means of transseptal left heart catheterization. II. Left ventricular function in high output heart diseases, especially in hyperthyroidism.", "content": "Clinical studies on the cardiac performance by means of transseptal left heart catheterization. II. Left ventricular function in high output heart diseases, especially in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221049"} {"pmid": "4221051", "title": "The effect of oral potassium chloride on the normal and abnormal electrocardiogram; studies on the ventricular gradient II.", "content": "The effect of oral potassium chloride on the normal and abnormal electrocardiogram; studies on the ventricular gradient II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221051"} {"pmid": "4221050", "title": "Nucleic acid metabolism in experimentally hypertrophied myocardium.", "content": "Nucleic acid metabolism in experimentally hypertrophied myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221050"} {"pmid": "4221053", "title": "Blood pressure elevation and renal pathology in rats fed simulated Japanese diets.", "content": "Blood pressure elevation and renal pathology in rats fed simulated Japanese diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221053"} {"pmid": "4221054", "title": "Vitamin B6 depletion in man: urinary excretion of quinolinic acid and niacin metabolites.", "content": "Vitamin B6 depletion in man: urinary excretion of quinolinic acid and niacin metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221054"} {"pmid": "4221059", "title": "The enzymatic degradation of heparin and heparitin sulfate. I. The fractionation of a crude heparinase from flavobacteria.", "content": "The enzymatic degradation of heparin and heparitin sulfate. I. The fractionation of a crude heparinase from flavobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221059"} {"pmid": "4221060", "title": "Characterization of the molecular region containing the active sites of myosin.", "content": "Characterization of the molecular region containing the active sites of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221060"} {"pmid": "4221061", "title": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. V. Properties of coupling factor 4.", "content": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. V. Properties of coupling factor 4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221061"} {"pmid": "4221062", "title": "Formation of a reactive myosin-phosphate complex as a key reaction in muscle contraction.", "content": "Formation of a reactive myosin-phosphate complex as a key reaction in muscle contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221062"} {"pmid": "4221071", "title": "Carbon monoxide poisoning.", "content": "Carbon monoxide poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221071"} {"pmid": "4221069", "title": "The pattern of innervation of the extrinsic ocular muscles and the intra-orbital ganglia of the albino mouse.", "content": "The pattern of innervation of the extrinsic ocular muscles and the intra-orbital ganglia of the albino mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221069"} {"pmid": "4221072", "title": "Anxiety--reappraisal of a concept.", "content": "Anxiety--reappraisal of a concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221072"} {"pmid": "4221073", "title": "Breech presentation in the primigravida.", "content": "Breech presentation in the primigravida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221073"} {"pmid": "4221074", "title": "Diagnosis of Cushing's syndrome.", "content": "Diagnosis of Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221074"} {"pmid": "4221076", "title": "Available services in nutrition and dietetics.", "content": "Available services in nutrition and dietetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221076"} {"pmid": "4221075", "title": "Electrocardiogram of the month.", "content": "Electrocardiogram of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221075"} {"pmid": "4221079", "title": "Multiple repeat caesarean section.", "content": "Multiple repeat caesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221079"} {"pmid": "4221081", "title": "Clinical pathologic conference.", "content": "Clinical pathologic conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221081"} {"pmid": "4221078", "title": "Early atherosclerosis in the pig: a histological and histochemical study.", "content": "Early atherosclerosis in the pig: a histological and histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221078"} {"pmid": "4221100", "title": "Fibrinolysin (human) in large therapeutic doses; its effect on hemostasis in wound-healing in dogs.", "content": "Fibrinolysin (human) in large therapeutic doses; its effect on hemostasis in wound-healing in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221100"} {"pmid": "4221101", "title": "Back pain: the problems of diagnosis.", "content": "Back pain: the problems of diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221101"} {"pmid": "4221103", "title": "Human dermal fibroblasts in monolayer tissue culture. Effect of ascorbic acid analogues.", "content": "Human dermal fibroblasts in monolayer tissue culture. Effect of ascorbic acid analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221103"} {"pmid": "4221104", "title": "Factors influencing the utilization of ketone bodies by mouse adipose tissue.", "content": "Factors influencing the utilization of ketone bodies by mouse adipose tissue. Factors influencing the utilization of ketone bodies by mouse adipose tissue in vitro were studied. Epididymal fat pads can oxidize DL-Beta-hydroxybutyrate-3-(14)C and acetoacetate-3-(14)C to (14)CO(2) as well as convert these compounds to fatty acid-(14)C. An increased output of (14)CO(2) from Beta-hydroxybutyrate-3-(14)C was noted in response to glucose plus insulin, succinate, oxaloacetate, L-asparate, and L-malate. Fatty acid synthesis from Beta-hydroxybutyrate was enhanced by glucose plus insulin, L-aspartate, L-malate, oxaloacetate, and citrate. Nicotinamide stimulated the oxidation of Beta-hydroxybutyrate but not of acetoacetate to CO(2), and did not affect fatty acid synthesis from either ketone body. Nicotinamide increased NAD(+) and NADP(+) levels in epididymal fat pads without affecting the concentration of NADH and NADPH. \"Superlipogenesis\" caused by fasting the mice for 48 hr and re-feeding them for 24 hr sharply enhanced CO(2) output and lipogenesis from Beta-hydroxybutyrate. The activities of glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, NADP-malic dehydrogenase, and citrate cleavage enzyme from mouse adipose tissue were increased during \"superlipogenesis.\" Free fatty acid release by epididymal fat pads in vitro was slightly increased by Beta-hydroxybutyrate. The relationship of ketone body metabolism and lipogenesis in adipose tissue is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221104"} {"pmid": "4221105", "title": "A comparative study of the influence of chlorpromazine and imipramine on mitochondrial activity. DNP- and Mg2+-activated ATPase, succinate dehydrogenase and aspartate transaminase.", "content": "A comparative study of the influence of chlorpromazine and imipramine on mitochondrial activity. DNP- and Mg2+-activated ATPase, succinate dehydrogenase and aspartate transaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221105"} {"pmid": "4221113", "title": "The possibility of predicting the response of patients with early breast cancer to subsequent endocrine ablation.", "content": "The possibility of predicting the response of patients with early breast cancer to subsequent endocrine ablation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221113"} {"pmid": "4221114", "title": "Effect of fluoropyrimidines on delayed cutaneous hypersensitivity.", "content": "Effect of fluoropyrimidines on delayed cutaneous hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221114"} {"pmid": "4221120", "title": "Formation in vitro of dehydroepiandrosterone conjugates in blood.", "content": "Formation in vitro of dehydroepiandrosterone conjugates in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221120"} {"pmid": "4221119", "title": "Interrelation between human chorionic gonadotrophin inhibitory activity in plasma and urine and the rate of urinary gonadotrophin excretion.", "content": "Interrelation between human chorionic gonadotrophin inhibitory activity in plasma and urine and the rate of urinary gonadotrophin excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221119"} {"pmid": "4221126", "title": "Monoamine oxidase activity of blood platelets and their ability to store 5-hydroxytryptamine in some mental deficiencies.", "content": "Monoamine oxidase activity of blood platelets and their ability to store 5-hydroxytryptamine in some mental deficiencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221126"} {"pmid": "4221115", "title": "The spine as an indicator.", "content": "The spine as an indicator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221115"} {"pmid": "4221130", "title": "Chromosomes in two cases with acute childhood leukemia.", "content": "Chromosomes in two cases with acute childhood leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221130"} {"pmid": "4221121", "title": "The phosvitin kinase enzyme of cerebral microsomes.", "content": "The phosvitin kinase enzyme of cerebral microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221121"} {"pmid": "4221123", "title": "Inhibition of the sodium-ion-stimulated adenosine triphosphatase after treatment of isolated guinea pig cerebral cortex with ouabain and other agents.", "content": "Inhibition of the sodium-ion-stimulated adenosine triphosphatase after treatment of isolated guinea pig cerebral cortex with ouabain and other agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221123"} {"pmid": "4221140", "title": "Sugar consumption in vitro of the muscle tissue of diabetic patients.", "content": "Sugar consumption in vitro of the muscle tissue of diabetic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221140"} {"pmid": "4221122", "title": "Sodium-potassium activated ATPase from spinal cord of normal and injured rats.", "content": "Sodium-potassium activated ATPase from spinal cord of normal and injured rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221122"} {"pmid": "4221143", "title": "Congenital aplasia of the myocardium of the right ventricle (Uhl's anomaly).", "content": "Congenital aplasia of the myocardium of the right ventricle (Uhl's anomaly).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221143"} {"pmid": "4221144", "title": "Clinical application of antidepressant agents in disabled and rehabilitation patients.", "content": "Clinical application of antidepressant agents in disabled and rehabilitation patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221144"} {"pmid": "4221145", "title": "Fibrinolytic activity in thrombosed veins.", "content": "Fibrinolytic activity in thrombosed veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221145"} {"pmid": "4221146", "title": "Inhibition of the biosynthesis of sulphurated mucopolysaccharides in metaphyseal cartilage of newborn pigs.", "content": "Inhibition of the biosynthesis of sulphurated mucopolysaccharides in metaphyseal cartilage of newborn pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221146"} {"pmid": "4221148", "title": "Recombination in bacteriophage T4: a mechanism.", "content": "Recombination in bacteriophage T4: a mechanism. Genetic recombination between rIl mutants of T4 bacteriophage grown in Escherichia coli can occur under conditions where DNA synthesis is strongly inhibited by 5-fluorodeoxyuridine. The small amount of DNA synthesized under these conditions cannot account for the observed frequency of recombinants. The major mechanism of recombination in this system is a process of breakage and rejoining.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221148"} {"pmid": "4221149", "title": "Influence of thiol-inhibiting substances on the effects of ethyl methane sulphonate (EMS) on chromosomes.", "content": "Influence of thiol-inhibiting substances on the effects of ethyl methane sulphonate (EMS) on chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221149"} {"pmid": "4221161", "title": "Histochemical study on localization of adenosine triphosphatase and 5-nucleotidase in the olfactory bulb of the rat.", "content": "Histochemical study on localization of adenosine triphosphatase and 5-nucleotidase in the olfactory bulb of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221161"} {"pmid": "4221163", "title": "Oral lesions of erythema multiforme. Histologic and histochemical observations.", "content": "Oral lesions of erythema multiforme. Histologic and histochemical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221163"} {"pmid": "4221164", "title": "Demodex folliculorum and rosacea. A clinical and histological study.", "content": "Demodex folliculorum and rosacea. A clinical and histological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221164"} {"pmid": "4221165", "title": "An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.", "content": "An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221165"} {"pmid": "4221177", "title": "Anomalous origin of the left coronary artery from the pulmonary artery.", "content": "Anomalous origin of the left coronary artery from the pulmonary artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221177"} {"pmid": "4221178", "title": "Congenital aortic stenosis due to failure of histogenesis of the aortic valve (myxoid dysplasia).", "content": "Congenital aortic stenosis due to failure of histogenesis of the aortic valve (myxoid dysplasia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221178"} {"pmid": "4221179", "title": "Syndrome of incomplete regional achondroplasia (ilium and ribs) with abdominal muscle dysplasia.", "content": "Syndrome of incomplete regional achondroplasia (ilium and ribs) with abdominal muscle dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221179"} {"pmid": "4221182", "title": "The aromatization of 10-methyl and 10-hydroxymethyl steroids by human placental microsomes.", "content": "The aromatization of 10-methyl and 10-hydroxymethyl steroids by human placental microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221182"} {"pmid": "4221183", "title": "Comparative anticoagulant effects of coumadin, heparin, and fibrinolysin on direct-current thrombosis of rat mesoappendix vessels.", "content": "Comparative anticoagulant effects of coumadin, heparin, and fibrinolysin on direct-current thrombosis of rat mesoappendix vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221183"} {"pmid": "4221184", "title": "The frequency of aganglionosis associated with imperforate anus.", "content": "The frequency of aganglionosis associated with imperforate anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221184"} {"pmid": "4221188", "title": "Control of the carriage of epidemic phage type staphylococci and recurrent sepsis by biological means.", "content": "Control of the carriage of epidemic phage type staphylococci and recurrent sepsis by biological means.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221188"} {"pmid": "4221186", "title": "Dermatoglyphics in translocation Down's syndrome.", "content": "Dermatoglyphics in translocation Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221186"} {"pmid": "4221189", "title": "Studies of male survivors of myocardial infarction. VI. The electrocardiogram.", "content": "Studies of male survivors of myocardial infarction. VI. The electrocardiogram. Electrocardiograms of 101 men who survived myocardial infarction for at least three months and were free of hypertension, heart failure and other significant disease were analyzed. Within the range of 30 to 70 years, age had no apparent influence on the ECG. Six ECGs were borderline, 79 were abnormal and 16 had returned to normal. Of those with the pattern of infarction, 56 were transmural and 22 nontransmural. For all cases, posterior involvement was somewhat more common than anterior (46 to 32), but it was less common in non-transmural infarction. Ventricular premature beats, always unifocal and few in number, were the only abnormality in rhythm. Atrial fibrillation was conspicuously absent. There were four instances of complete left bundle-branch block. No evidence of left ventricular hypertrophy was seen. The clinical significance of these observations is briefly discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221189"} {"pmid": "4221190", "title": "The concept of susceptibility to hearing loss.", "content": "The concept of susceptibility to hearing loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221190"} {"pmid": "4221191", "title": "Medical aspects of invalidity retirement programs in Europe. II.", "content": "Medical aspects of invalidity retirement programs in Europe. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221191"} {"pmid": "4221192", "title": "Compensation for injuries while commuting to and from work.", "content": "Compensation for injuries while commuting to and from work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221192"} {"pmid": "4221194", "title": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 4. Regression of deciduomata.", "content": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 4. Regression of deciduomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221194"} {"pmid": "4221193", "title": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 3. Formation of deciduomata.", "content": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 3. Formation of deciduomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221193"} {"pmid": "4221195", "title": "The acid mucopolysaccharides. These essential components of living tissue exhibit demonstrable alterations of diagnostic assistance in certain diseases.", "content": "The acid mucopolysaccharides. These essential components of living tissue exhibit demonstrable alterations of diagnostic assistance in certain diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221195"} {"pmid": "4221200", "title": "Chromosomal aberrations in acute leukemia.", "content": "Chromosomal aberrations in acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221200"} {"pmid": "4221201", "title": "Comparative biochemistry of keratosulfates.", "content": "Comparative biochemistry of keratosulfates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221201"} {"pmid": "4221202", "title": "Mechanism of formation of bovine plasminogen activator from human plasmin.", "content": "Mechanism of formation of bovine plasminogen activator from human plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221202"} {"pmid": "4221203", "title": "Adenosine triphosphatase activity of yeast hexokinase and its relation to the mechanism of the hexokinase reaction.", "content": "Adenosine triphosphatase activity of yeast hexokinase and its relation to the mechanism of the hexokinase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221203"} {"pmid": "4221204", "title": "Studies on the secretion and interconversion of the androgens. II. Methods for estimation of rates of secretion and of metabolism from specific activities of urinary metabolites.", "content": "Studies on the secretion and interconversion of the androgens. II. Methods for estimation of rates of secretion and of metabolism from specific activities of urinary metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221204"} {"pmid": "4221205", "title": "Studies on the secretion and interconversion of the androgens. 3. Results obtained after the injection of several radioactive C-19 steroids, singly or as mixtures.", "content": "Studies on the secretion and interconversion of the androgens. 3. Results obtained after the injection of several radioactive C-19 steroids, singly or as mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221205"} {"pmid": "4221207", "title": "Physically crippled, but emotionally secure.", "content": "Physically crippled, but emotionally secure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221207"} {"pmid": "4221206", "title": "Plasma testosterone and estrogen levels, urine testosterone excretion, and sebum production in males with acne vulgaris.", "content": "Plasma testosterone and estrogen levels, urine testosterone excretion, and sebum production in males with acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221206"} {"pmid": "4221209", "title": "Re-employment or retirement. Background and definitive statement of the problem of disability.", "content": "Re-employment or retirement. Background and definitive statement of the problem of disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221209"} {"pmid": "4221211", "title": "Oral enzyme therapy in treatment of acne: a preliminary report.", "content": "Oral enzyme therapy in treatment of acne: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221211"} {"pmid": "4221210", "title": "Scleredema.", "content": "Scleredema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221210"} {"pmid": "4221212", "title": "Lysis of arterial clots. Using fibrinolysin in an isolation perfusion system.", "content": "Lysis of arterial clots. Using fibrinolysin in an isolation perfusion system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221212"} {"pmid": "4221214", "title": "The cardiac pathology of chronic exogenous obesity.", "content": "The cardiac pathology of chronic exogenous obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221214"} {"pmid": "4221215", "title": "Prolonged bed rest in the treatment of the dilated heart.", "content": "Prolonged bed rest in the treatment of the dilated heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221215"} {"pmid": "4221216", "title": "The identification of successful teachers of mentally or physically handicapped children.", "content": "The identification of successful teachers of mentally or physically handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221216"} {"pmid": "4221218", "title": "Effect of irradiation on vascular permeability and on blood mucopolysaccharide and serotonin levels.", "content": "Effect of irradiation on vascular permeability and on blood mucopolysaccharide and serotonin levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221218"} {"pmid": "4221217", "title": "Changes in heart muscle and liver proteins in experimental myocardial infarction.", "content": "Changes in heart muscle and liver proteins in experimental myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221217"} {"pmid": "4221233", "title": "Benzene and dioxane electric moments of N-alkyl-substituted nicotinamides from measurements in mixed benzene--dioxane solutions.", "content": "Benzene and dioxane electric moments of N-alkyl-substituted nicotinamides from measurements in mixed benzene--dioxane solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221233"} {"pmid": "4221236", "title": "Thyroid function in mongoloid children. Thyroxine-binding capacity.", "content": "Thyroid function in mongoloid children. Thyroxine-binding capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221236"} {"pmid": "4221237", "title": "Management of femoral artery obstruction. Complications of femoral venipuncture.", "content": "Management of femoral artery obstruction. Complications of femoral venipuncture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221237"} {"pmid": "4221240", "title": "The management of tube pedicles.", "content": "The management of tube pedicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221240"} {"pmid": "4221242", "title": "The effects of temperature on the isolated muscle spindle.", "content": "The effects of temperature on the isolated muscle spindle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221242"} {"pmid": "4221244", "title": "A bath that folds--from Sweden. To facilitate bathing of very ill or disabled patients.", "content": "A bath that folds--from Sweden. To facilitate bathing of very ill or disabled patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221244"} {"pmid": "4221243", "title": "Motor fibres innervating extrafusal and intrafusal muscle fibres in the cat.", "content": "Motor fibres innervating extrafusal and intrafusal muscle fibres in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221243"} {"pmid": "4221246", "title": "Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Mavilla, Vega Alta, Puerto Rico.", "content": "Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Mavilla, Vega Alta, Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221246"} {"pmid": "4221248", "title": "Regulatory mechanisms in carbohydrate metabolism. VII. Hexokinase and phosphofructokinase.", "content": "Regulatory mechanisms in carbohydrate metabolism. VII. Hexokinase and phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221248"} {"pmid": "4221249", "title": "Regulatory mechanisms in carbohydrate metabolism. 8. The regulatory function of phosphate in glycolysis.", "content": "Regulatory mechanisms in carbohydrate metabolism. 8. The regulatory function of phosphate in glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221249"} {"pmid": "4221250", "title": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. VI. Studies on the mechanism of cold inactivation of mitochondrial adenosine triphosphatase.", "content": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. VI. Studies on the mechanism of cold inactivation of mitochondrial adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221250"} {"pmid": "4221251", "title": "Dio-9, an inhibitor of coupled electron transport and phosphorylation in chloroplasts.", "content": "Dio-9, an inhibitor of coupled electron transport and phosphorylation in chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221251"} {"pmid": "4221245", "title": "In right good company.", "content": "In right good company.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221245"} {"pmid": "4221254", "title": "Pediatric conditions related to diseases and functions of the placenta.", "content": "Pediatric conditions related to diseases and functions of the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221254"} {"pmid": "4221255", "title": "Birth trends in Nebraska.", "content": "Birth trends in Nebraska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221255"} {"pmid": "4221256", "title": "Neurologic manifestations of dysbarism (decompression sickness).", "content": "Neurologic manifestations of dysbarism (decompression sickness).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221256"} {"pmid": "4221258", "title": "Etiology of carcinoma: genetic determinism.", "content": "Etiology of carcinoma: genetic determinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221258"} {"pmid": "4221257", "title": "The acute abdomen complicating pregnancy.", "content": "The acute abdomen complicating pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221257"} {"pmid": "4221259", "title": "XII. The disabled patient at home.", "content": "XII. The disabled patient at home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221259"} {"pmid": "4221260", "title": "Subcutaneous rupture of the rectus abdominus muscle with incarcerated hernia and bowel obstruction.", "content": "Subcutaneous rupture of the rectus abdominus muscle with incarcerated hernia and bowel obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221260"} {"pmid": "4221261", "title": "Reflex discharges in phrenic and abdominal muscle nerves to vagal afferent nerve stimulation.", "content": "Reflex discharges in phrenic and abdominal muscle nerves to vagal afferent nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221261"} {"pmid": "4221262", "title": "Low backache.", "content": "Low backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221262"} {"pmid": "4221277", "title": "Differentiation of the skeletal muscle in the chicken. 8. ATPase activity during development.", "content": "Differentiation of the skeletal muscle in the chicken. 8. ATPase activity during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221277"} {"pmid": "4221278", "title": "Platelet agglutination and deagglutination with a sulfhydryl inhibitor, methyl mercuric nitrate: relationships to platelet ATPase.", "content": "Platelet agglutination and deagglutination with a sulfhydryl inhibitor, methyl mercuric nitrate: relationships to platelet ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221278"} {"pmid": "4221279", "title": "Nuclear lobe count and incidence of drumsticks in Indian children with Down's syndrome.", "content": "Nuclear lobe count and incidence of drumsticks in Indian children with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221279"} {"pmid": "4221282", "title": "Testicular feminization.", "content": "Testicular feminization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221282"} {"pmid": "4221283", "title": "Familial male hermaphroditism with delayed and partial masculinization.", "content": "Familial male hermaphroditism with delayed and partial masculinization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221283"} {"pmid": "4221291", "title": "Mongolism in newborn infants. An examination of the criteria for recognition and some speculations on the pathogenic activity of the chromosomal abnormality.", "content": "Mongolism in newborn infants. An examination of the criteria for recognition and some speculations on the pathogenic activity of the chromosomal abnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221291"} {"pmid": "4221292", "title": "An autopsy case of Sézary's reticulosis.", "content": "An autopsy case of Sézary's reticulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221292"} {"pmid": "4221293", "title": "Studies on acid mucopolysaccharides of pig gastric mucin. I.", "content": "Studies on acid mucopolysaccharides of pig gastric mucin. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221293"} {"pmid": "4221297", "title": "Biochemical differentiation of trisomic Down's syndrome (mongolism) from that due to translocation.", "content": "Biochemical differentiation of trisomic Down's syndrome (mongolism) from that due to translocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221297"} {"pmid": "4221310", "title": "The orthopedic aspects of low back pain.", "content": "The orthopedic aspects of low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221310"} {"pmid": "4221315", "title": "Occupational dermatitis.", "content": "Occupational dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221315"} {"pmid": "4221316", "title": "Diagnosis of industrial dermatitis.", "content": "Diagnosis of industrial dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221316"} {"pmid": "4221317", "title": "Handicapped children. The problem and a plan for their rehabilitation.", "content": "Handicapped children. The problem and a plan for their rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221317"} {"pmid": "4221318", "title": "Current occupational health in Latin America.", "content": "Current occupational health in Latin America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221318"} {"pmid": "4221319", "title": "Compensation for injuries in fighting.", "content": "Compensation for injuries in fighting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221319"} {"pmid": "4221320", "title": "Remediation of learning disabilities in a public school system.", "content": "Remediation of learning disabilities in a public school system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221320"} {"pmid": "4221321", "title": "Body image of crippled children as seen in draw-a-person test behavior.", "content": "Body image of crippled children as seen in draw-a-person test behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221321"} {"pmid": "4221322", "title": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. I. Framework: oestrous cycle and pseudopregnancy.", "content": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. I. Framework: oestrous cycle and pseudopregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221322"} {"pmid": "4221323", "title": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. II. Induction.", "content": "Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. II. Induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221323"} {"pmid": "4221324", "title": "Acute anemia and abdominal tumor due to hemorrhage in rectus abdominis sheath following anticoagulant therapy.", "content": "Acute anemia and abdominal tumor due to hemorrhage in rectus abdominis sheath following anticoagulant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221324"} {"pmid": "4221325", "title": "Chromosome studies on a radiographer and her family. Report of one case of leukemia and two cases of Down's syndrome.", "content": "Chromosome studies on a radiographer and her family. Report of one case of leukemia and two cases of Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221325"} {"pmid": "4221326", "title": "A simple test for inactivation of an enzyme during assay.", "content": "A simple test for inactivation of an enzyme during assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221326"} {"pmid": "4221329", "title": "Effect of the antimetabolite, 6-aminonicotinamide, on sound-induced seizures in mice.", "content": "Effect of the antimetabolite, 6-aminonicotinamide, on sound-induced seizures in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221329"} {"pmid": "4221332", "title": "Vocational rehabilitation service in a general hospital.", "content": "Vocational rehabilitation service in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221332"} {"pmid": "4221333", "title": "The effect of nucleic acid antagonists on cell division and oral organelle development in Tetrahymena pyriformis.", "content": "The effect of nucleic acid antagonists on cell division and oral organelle development in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221333"} {"pmid": "4221354", "title": "Beryllium disease. Report of the section of nature and prevalence committee on occupational diseases of the chest--American College of Chest Physicians.", "content": "Beryllium disease. Report of the section of nature and prevalence committee on occupational diseases of the chest--American College of Chest Physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221354"} {"pmid": "4221355", "title": "Demonstration of 3-beta-hydroxysteroid dehydrogenase in the testis of Tilapia mossambica (Cichlidae, Teleostei).", "content": "Demonstration of 3-beta-hydroxysteroid dehydrogenase in the testis of Tilapia mossambica (Cichlidae, Teleostei).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221355"} {"pmid": "4221356", "title": "Intramuscular pressure changes during contraction in relation to muscle spindles.", "content": "Intramuscular pressure changes during contraction in relation to muscle spindles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221356"} {"pmid": "4221357", "title": "Effects of heparin, plasmin, dextran and low-molecular-weight dextran on electrically induced thromboses.", "content": "Effects of heparin, plasmin, dextran and low-molecular-weight dextran on electrically induced thromboses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221357"} {"pmid": "4221363", "title": "The challenge of research in oral pediatrics.", "content": "The challenge of research in oral pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221363"} {"pmid": "4221367", "title": "The effect of oligomycin on the respiration of tissue slices.", "content": "The effect of oligomycin on the respiration of tissue slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221367"} {"pmid": "4221368", "title": "The effect of long-chain fatty acids on orthophosphate-adenosine 5'-triphosphate exchange activity associated with oxidative phosphorylation.", "content": "The effect of long-chain fatty acids on orthophosphate-adenosine 5'-triphosphate exchange activity associated with oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221368"} {"pmid": "4221369", "title": "The role of CA2+ in the adenosine triphosphatase activity of myofibrils.", "content": "The role of CA2+ in the adenosine triphosphatase activity of myofibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221369"} {"pmid": "4221379", "title": "A method for the demonstration of sulphated mucopolysaccharides in tissue sections.", "content": "A method for the demonstration of sulphated mucopolysaccharides in tissue sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221379"} {"pmid": "4221380", "title": "Cutaneous focal mucinosis. A clinicopathological and histochemical study.", "content": "Cutaneous focal mucinosis. A clinicopathological and histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221380"} {"pmid": "4221381", "title": "Scleromyxedema. A variant of Lichen myxedematosus.", "content": "Scleromyxedema. A variant of Lichen myxedematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221381"} {"pmid": "4221382", "title": "Tetracycline sun sensitivity.", "content": "Tetracycline sun sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221382"} {"pmid": "4221383", "title": "Oral tetracycline treatment on bacterial flora in acne vulgaris.", "content": "Oral tetracycline treatment on bacterial flora in acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221383"} {"pmid": "4221385", "title": "The uses and limitations of hypnosis in children's dentistry.", "content": "The uses and limitations of hypnosis in children's dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221385"} {"pmid": "4221384", "title": "The child, the parent and the dentist.", "content": "The child, the parent and the dentist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221384"} {"pmid": "4221386", "title": "How many disabled?", "content": "How many disabled?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221386"} {"pmid": "4221388", "title": "Activity patterns of purified ATPase from Arachis hypogaea.", "content": "Activity patterns of purified ATPase from Arachis hypogaea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221388"} {"pmid": "4221389", "title": "Legal implications of the battered child syndrome.", "content": "Legal implications of the battered child syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221389"} {"pmid": "4221390", "title": "Wilful abuse of children.", "content": "Wilful abuse of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221390"} {"pmid": "4221391", "title": "Response of malignancy to phenylalanine restriction. A preliminary report on a new concept of managing malignant disease.", "content": "Response of malignancy to phenylalanine restriction. A preliminary report on a new concept of managing malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221391"} {"pmid": "4221392", "title": "\"Nonparticipation\" and the Sherman Act.", "content": "\"Nonparticipation\" and the Sherman Act.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221392"} {"pmid": "4221393", "title": "\"The role of Blue Shield in the medicare program\".", "content": "\"The role of Blue Shield in the medicare program\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221393"} {"pmid": "4221395", "title": "A rapid method for the assay of small quantities of sulfomucopolysaccharides.", "content": "A rapid method for the assay of small quantities of sulfomucopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221395"} {"pmid": "4221397", "title": "The variation of adenosine triphosphate and adenosine triphosphatase in Tribolium confusum, Duval at the different stages of its life cycle.", "content": "The variation of adenosine triphosphate and adenosine triphosphatase in Tribolium confusum, Duval at the different stages of its life cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221397"} {"pmid": "4221399", "title": "An address given at the dedication of the Davis Woolf Goldstein Library.", "content": "An address given at the dedication of the Davis Woolf Goldstein Library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221399"} {"pmid": "4221400", "title": "Olfactory groove meningioma: herniation following spinal anesthesia.", "content": "Olfactory groove meningioma: herniation following spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221400"} {"pmid": "4221401", "title": "Disaccharide intolerance.", "content": "Disaccharide intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221401"} {"pmid": "4221402", "title": "Leukoplakia of the vulva.", "content": "Leukoplakia of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221402"} {"pmid": "4221403", "title": "The humoral regulation of erythropoiesis.", "content": "The humoral regulation of erythropoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221403"} {"pmid": "4221404", "title": "Typhoid fever.", "content": "Typhoid fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221404"} {"pmid": "4221405", "title": "The role of lysosomes in hypersensitivity reactions: tissue damage by polymorphonuclear neutrophil lysosomes.", "content": "The role of lysosomes in hypersensitivity reactions: tissue damage by polymorphonuclear neutrophil lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221405"} {"pmid": "4221407", "title": "Immunization in virus disease.", "content": "Immunization in virus disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221407"} {"pmid": "4221406", "title": "Targets of population in Singapore.", "content": "Targets of population in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221406"} {"pmid": "4221408", "title": "Factors affecting prognosis of choriocarcioma.", "content": "Factors affecting prognosis of choriocarcioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221408"} {"pmid": "4221409", "title": "A plea against abdominal hysterotomy in the treatment of hydatidiform mole.", "content": "A plea against abdominal hysterotomy in the treatment of hydatidiform mole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221409"} {"pmid": "4221410", "title": "Behaviour therapy.", "content": "Behaviour therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221410"} {"pmid": "4221411", "title": "A malaria parasite, plasmodium (Vinckeia) booliati sp.nov., from a Malayan giant flying squirrel.", "content": "A malaria parasite, plasmodium (Vinckeia) booliati sp.nov., from a Malayan giant flying squirrel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221411"} {"pmid": "4221412", "title": "Pudendal block anaesthesia. A new technique in regional anaesthesia with special reference to forceps delivery.", "content": "Pudendal block anaesthesia. A new technique in regional anaesthesia with special reference to forceps delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221412"} {"pmid": "4221413", "title": "Aflatoxins in unrefined groundnut oil.", "content": "Aflatoxins in unrefined groundnut oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221413"} {"pmid": "4221414", "title": "The oxygen consumption of Plasmodium berghei in the presence of normal rat serum, immune rat serum and chloroquine sulfate.", "content": "The oxygen consumption of Plasmodium berghei in the presence of normal rat serum, immune rat serum and chloroquine sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221414"} {"pmid": "4221415", "title": "Systematic and distributional studies of helminths of Malayan mammals.", "content": "Systematic and distributional studies of helminths of Malayan mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221415"} {"pmid": "4221416", "title": "Studies on the cytology and histology of helminths.", "content": "Studies on the cytology and histology of helminths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221416"} {"pmid": "4221417", "title": "The lymphatic system of a species of amphistome.", "content": "The lymphatic system of a species of amphistome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221417"} {"pmid": "4221418", "title": "Morphological, histological and cytological studies on the nervous system of Ceylonocotyle sp. (Paramphistomata).", "content": "Morphological, histological and cytological studies on the nervous system of Ceylonocotyle sp. (Paramphistomata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221418"} {"pmid": "4221419", "title": "The life-history of Echinostoma ilocanum.", "content": "The life-history of Echinostoma ilocanum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221419"} {"pmid": "4221421", "title": "Multiple infections of larval trematodes in one snail.", "content": "Multiple infections of larval trematodes in one snail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221421"} {"pmid": "4221420", "title": "The life cycle of two brachylaimid flukes in Malaysia.", "content": "The life cycle of two brachylaimid flukes in Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221420"} {"pmid": "4221422", "title": "Fascioliasis in cattle near Kuala Lumpur.", "content": "Fascioliasis in cattle near Kuala Lumpur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221422"} {"pmid": "4221423", "title": "A single abnormal proglottid Taenia saginata.", "content": "A single abnormal proglottid Taenia saginata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221423"} {"pmid": "4221424", "title": "The size of microfilariae in relation to the storage time of unfixed and fixed thick blood films.", "content": "The size of microfilariae in relation to the storage time of unfixed and fixed thick blood films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221424"} {"pmid": "4221425", "title": "Intraocular parasitism.", "content": "Intraocular parasitism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221425"} {"pmid": "4221426", "title": "Correlation of habitat to rodent susceptibility with Angiostrongylus cantonensis (Nematoda: Metastrongylidae).", "content": "Correlation of habitat to rodent susceptibility with Angiostrongylus cantonensis (Nematoda: Metastrongylidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221426"} {"pmid": "4221427", "title": "Studies on Hepatojarakus malayae Yeh, 1955 (Trichostrongylidae: Nematoda).", "content": "Studies on Hepatojarakus malayae Yeh, 1955 (Trichostrongylidae: Nematoda).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221427"} {"pmid": "4221428", "title": "Observations on the presence of immunity in rats to Angiostrongylus cantonensis (Chen).", "content": "Observations on the presence of immunity in rats to Angiostrongylus cantonensis (Chen).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221428"} {"pmid": "4221429", "title": "The American cockroach, Periplanta americana, as an intermediate host of the pentastomid, Raillietiella hemidactyli.", "content": "The American cockroach, Periplanta americana, as an intermediate host of the pentastomid, Raillietiella hemidactyli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221429"} {"pmid": "4221430", "title": "Laboratory observations on the comparative feeding preferences by Aedes schuellaris malayensis from Kuantan and Singapore.", "content": "Laboratory observations on the comparative feeding preferences by Aedes schuellaris malayensis from Kuantan and Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221430"} {"pmid": "4221431", "title": "Anopheles maculatus, a new vector of Wuchereria bancrofti in Malaysia (Pulau Aur) and a potential vector on mainland Malaya.", "content": "Anopheles maculatus, a new vector of Wuchereria bancrofti in Malaysia (Pulau Aur) and a potential vector on mainland Malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221431"} {"pmid": "4221432", "title": "Anopheles philippinensis, a new host record of Coelomomyces sp. in Perlis.", "content": "Anopheles philippinensis, a new host record of Coelomomyces sp. in Perlis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221432"} {"pmid": "4221434", "title": "A tracheal mite from Valanga nigricornis Burm. (Orthoptera: Acrididae).", "content": "A tracheal mite from Valanga nigricornis Burm. (Orthoptera: Acrididae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221434"} {"pmid": "4221433", "title": "Anopheles balabacensis balabacensis identified as a vector of monkey malaria in malaya.", "content": "Anopheles balabacensis balabacensis identified as a vector of monkey malaria in malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221433"} {"pmid": "4221435", "title": "The unusual life-history of Vatacarus ipoides Southcott (Acarina, Trombiculidae).", "content": "The unusual life-history of Vatacarus ipoides Southcott (Acarina, Trombiculidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221435"} {"pmid": "4221436", "title": "Laboratory diagnosis of trachoma.", "content": "Laboratory diagnosis of trachoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221436"} {"pmid": "4221438", "title": "Laboratory diagnosis of haemorrhagic fever.", "content": "Laboratory diagnosis of haemorrhagic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221438"} {"pmid": "4221437", "title": "Rapid typing of dengue viruses by the microprecipitin agar gel diffusion technique.", "content": "Rapid typing of dengue viruses by the microprecipitin agar gel diffusion technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221437"} {"pmid": "4221439", "title": "Mycotic Keratitis.", "content": "Mycotic Keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221439"} {"pmid": "4221440", "title": "Coagulation of Malays and caucasians: a comparative study of two groups of young soldiers.", "content": "Coagulation of Malays and caucasians: a comparative study of two groups of young soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221440"} {"pmid": "4221441", "title": "Freeze-dried smallpox vaccine; report of a trial in Kuala Lumpur.", "content": "Freeze-dried smallpox vaccine; report of a trial in Kuala Lumpur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221441"} {"pmid": "4221443", "title": "A familial minute isochromosome.", "content": "A familial minute isochromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221443"} {"pmid": "4221444", "title": "Autoimmunity and chromosomal aberrations.", "content": "Autoimmunity and chromosomal aberrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221444"} {"pmid": "4221457", "title": "The bacteriology of tropical pyomyositis in Uganda.", "content": "The bacteriology of tropical pyomyositis in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221457"} {"pmid": "4221458", "title": "Rhabdomyosarcoma.", "content": "Rhabdomyosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221458"} {"pmid": "4221459", "title": "Tuberculosis: is it compensable or not?", "content": "Tuberculosis: is it compensable or not?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221459"} {"pmid": "4221461", "title": "More help in the home for the handicapped.", "content": "More help in the home for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221461"} {"pmid": "4221463", "title": "The relaxing incision in the anterior rectus sheath in the operative treatment of inguinal hernia.", "content": "The relaxing incision in the anterior rectus sheath in the operative treatment of inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221463"} {"pmid": "4221469", "title": "The sulfated mucopolysaccharides from human umbilical cord.", "content": "The sulfated mucopolysaccharides from human umbilical cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221469"} {"pmid": "4221470", "title": "The genetic mucopolysaccharidoses.", "content": "The genetic mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221470"} {"pmid": "4221478", "title": "A state department-university approach in providing internship experiences for prospective leadership personnel in special education.", "content": "A state department-university approach in providing internship experiences for prospective leadership personnel in special education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221478"} {"pmid": "4221479", "title": "Psychological needs and preferences for teaching exceptional children.", "content": "Psychological needs and preferences for teaching exceptional children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221479"} {"pmid": "4221480", "title": "Effectiveness of an academically oriented teaching program with crippled children.", "content": "Effectiveness of an academically oriented teaching program with crippled children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221480"} {"pmid": "4221481", "title": "The origin of spontaneous contractions and changes in neuromuscular transmission in barium-treated muscle.", "content": "The origin of spontaneous contractions and changes in neuromuscular transmission in barium-treated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221481"} {"pmid": "4221486", "title": "Experimental collagen-like disease induced by repeated injections of papain, with evidence of autoimmune antibodies.", "content": "Experimental collagen-like disease induced by repeated injections of papain, with evidence of autoimmune antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221486"} {"pmid": "4221489", "title": "Exchange of cerebrospinal fluid potassium with blood and brain. Study in normal and Ouabain perfused cats.", "content": "Exchange of cerebrospinal fluid potassium with blood and brain. Study in normal and Ouabain perfused cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221489"} {"pmid": "4221488", "title": "Effect of quinones on mitochondrial phosphorylation, Pi-ATP exchange, and ATPase activities. II. Vitamin K-2 homologues and K-1 derivatives.", "content": "Effect of quinones on mitochondrial phosphorylation, Pi-ATP exchange, and ATPase activities. II. Vitamin K-2 homologues and K-1 derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221488"} {"pmid": "4221490", "title": "Increased brain radiocopper uptake in Wilson's disease.", "content": "Increased brain radiocopper uptake in Wilson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221490"} {"pmid": "4221493", "title": "The handicapped child and the law.", "content": "The handicapped child and the law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221493"} {"pmid": "4221496", "title": "Thrombelastographic patterns produced by fibrinolytic agents incorporated in fibrin.", "content": "Thrombelastographic patterns produced by fibrinolytic agents incorporated in fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221496"} {"pmid": "4221497", "title": "Fusimotor function during sleep in unrestrained cats. An account of the modulation of the mechanically and electrically evoked monosynaptic reflexes.", "content": "Fusimotor function during sleep in unrestrained cats. An account of the modulation of the mechanically and electrically evoked monosynaptic reflexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221497"} {"pmid": "4221498", "title": "Gaps in the nation's services for children.", "content": "Gaps in the nation's services for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221498"} {"pmid": "4221499", "title": "Alpha-rigidity in reserpinized rats.", "content": "Alpha-rigidity in reserpinized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221499"} {"pmid": "4221500", "title": "Pediatric dental rehabilitation.", "content": "Pediatric dental rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221500"} {"pmid": "4221501", "title": "Behavioral patterns of the child patient.", "content": "Behavioral patterns of the child patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221501"} {"pmid": "4221502", "title": "A survey of pediatric dentistry in Cincinnati.", "content": "A survey of pediatric dentistry in Cincinnati.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221502"} {"pmid": "4221495", "title": "Age changes in content of sulfhydryl groups and adenosinetriphosphatase activity of myosin.", "content": "Age changes in content of sulfhydryl groups and adenosinetriphosphatase activity of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221495"} {"pmid": "4221494", "title": "Effect of heavy water D2-O on resistance of plant and animal cells, cell models and proteins to certain denaturing factors.", "content": "Effect of heavy water D2-O on resistance of plant and animal cells, cell models and proteins to certain denaturing factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221494"} {"pmid": "4221504", "title": "The role of the public health nurse in the discharge of the handicapped child to the community.", "content": "The role of the public health nurse in the discharge of the handicapped child to the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221504"} {"pmid": "4221505", "title": "Food and rehabilitation of the handicapped.", "content": "Food and rehabilitation of the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221505"} {"pmid": "4221511", "title": "Urinary excretion of mucopolysaccharides in normal individuals and in the Marfan syndrome.", "content": "Urinary excretion of mucopolysaccharides in normal individuals and in the Marfan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221511"} {"pmid": "4221512", "title": "Analysis of mucopolysaccharides in partially aqueous media.", "content": "Analysis of mucopolysaccharides in partially aqueous media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221512"} {"pmid": "4221513", "title": "Optical rotatory dispersion of mucopolysaccharides and mucopolysaccharide-dye complexes.", "content": "Optical rotatory dispersion of mucopolysaccharides and mucopolysaccharide-dye complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221513"} {"pmid": "4221515", "title": "A possible mechanism for the anti-inflammatory effects of proteolytic enzymes.", "content": "A possible mechanism for the anti-inflammatory effects of proteolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221515"} {"pmid": "4221514", "title": "A case of idiopathic cavitation of lung demonstrated at the Postgraduate Medical School of London.", "content": "A case of idiopathic cavitation of lung demonstrated at the Postgraduate Medical School of London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221514"} {"pmid": "4221516", "title": "Selenium and rabbit skeletal muscle aldolase and myosin.", "content": "Selenium and rabbit skeletal muscle aldolase and myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221516"} {"pmid": "4221517", "title": "A dental service for children with bleeding disorders.", "content": "A dental service for children with bleeding disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221517"} {"pmid": "4221518", "title": "Studies in myocarditis. 3. On the frequency and nature of some common symptoms.", "content": "Studies in myocarditis. 3. On the frequency and nature of some common symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221518"} {"pmid": "4221520", "title": "The \"dimeric acid product\" of 1-methyl-1,4-dihydronicotinamide.", "content": "The \"dimeric acid product\" of 1-methyl-1,4-dihydronicotinamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221520"} {"pmid": "4221521", "title": "The effect of ouabain on the hydration and the adenosine triphosphatase activity of the cornea.", "content": "The effect of ouabain on the hydration and the adenosine triphosphatase activity of the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221521"} {"pmid": "4221522", "title": "Hereditary renal disease associated with deafness; Alport's syndrome.", "content": "Hereditary renal disease associated with deafness; Alport's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221522"} {"pmid": "4221523", "title": "Two cases of atypical leukoencephalitis.", "content": "Two cases of atypical leukoencephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221523"} {"pmid": "4221524", "title": "A contribution to the study of the body axis in mammals with special reference to domesticated dog.", "content": "A contribution to the study of the body axis in mammals with special reference to domesticated dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221524"} {"pmid": "4221525", "title": "The torsion of the roots in human lower molars.", "content": "The torsion of the roots in human lower molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221525"} {"pmid": "4221526", "title": "Finger patterns and ridge counts of the Dogons.", "content": "Finger patterns and ridge counts of the Dogons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221526"} {"pmid": "4221527", "title": "The influence of plasma substitutes on the suspension stability of human blood.", "content": "The influence of plasma substitutes on the suspension stability of human blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221527"} {"pmid": "4221528", "title": "Left ventricular enlargement and hypertrophy. A clinical and angiocardiographic study.", "content": "Left ventricular enlargement and hypertrophy. A clinical and angiocardiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221528"} {"pmid": "4221529", "title": "Mucopolysaccharides in sweat.", "content": "Mucopolysaccharides in sweat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221529"} {"pmid": "4221530", "title": "A gastroenteritis outbreak of Staphylococcus aureus, type 29.", "content": "A gastroenteritis outbreak of Staphylococcus aureus, type 29.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221530"} {"pmid": "4221535", "title": "Lymphoblast transformation in sulphonamide sensitivity.", "content": "Lymphoblast transformation in sulphonamide sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221535"} {"pmid": "4221547", "title": "The dental management of the physically handicapped child.", "content": "The dental management of the physically handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221547"} {"pmid": "4221548", "title": "Fatal case of toxic erythema after chlorpropamide (Diabinese).", "content": "Fatal case of toxic erythema after chlorpropamide (Diabinese).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221548"} {"pmid": "4221549", "title": "Studies on the biological activity of Rhus striata (\"manzanillo\"). I. Hemolytic activity.", "content": "Studies on the biological activity of Rhus striata (\"manzanillo\"). I. Hemolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221549"} {"pmid": "4221536", "title": "The effect of ovarian hormones on the sulphomucopolysaccharides of the uterus.", "content": "The effect of ovarian hormones on the sulphomucopolysaccharides of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221536"} {"pmid": "4221537", "title": "On the histochemical nomenclature for sialomucins.", "content": "On the histochemical nomenclature for sialomucins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221537"} {"pmid": "4221551", "title": "Back pain in a young man.", "content": "Back pain in a young man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221551"} {"pmid": "4221550", "title": "Development of activity of 3 beta-hydroxysteroid dehydrogenase in human fetal tissues and in two anencephalic newborns.", "content": "Development of activity of 3 beta-hydroxysteroid dehydrogenase in human fetal tissues and in two anencephalic newborns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221550"} {"pmid": "4221552", "title": "The pathogenesis of ocular lesions of infectious canine hepatitis. II. Experimental ocular hypersensitivity produced by the virus.", "content": "The pathogenesis of ocular lesions of infectious canine hepatitis. II. Experimental ocular hypersensitivity produced by the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221552"} {"pmid": "4221559", "title": "Metabolic processes in skin.", "content": "Metabolic processes in skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221559"} {"pmid": "4221560", "title": "The effect of progesterone on the sebaceous glands of the rat.", "content": "The effect of progesterone on the sebaceous glands of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221560"} {"pmid": "4221561", "title": "Periodicity of S35 uptake in rat femurs.", "content": "Periodicity of S35 uptake in rat femurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221561"} {"pmid": "4221563", "title": "Psychologic factors in backache.", "content": "Psychologic factors in backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221563"} {"pmid": "4221562", "title": "Similar cytological effects of hydroxylamine and 5-FUDR, agents with different modes of action. An analysis of chromosome breakage.", "content": "Similar cytological effects of hydroxylamine and 5-FUDR, agents with different modes of action. An analysis of chromosome breakage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221562"} {"pmid": "4221564", "title": "Impetigo in the Waikato.", "content": "Impetigo in the Waikato.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221564"} {"pmid": "4221565", "title": "Basophilic leucocytes and Hashimoto's thyroiditis. Skin reaction upon intradermal injection of thyroid extract studied by skin window technique.", "content": "Basophilic leucocytes and Hashimoto's thyroiditis. Skin reaction upon intradermal injection of thyroid extract studied by skin window technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221565"} {"pmid": "4221567", "title": "New help for the severely retarded and emotionally disturbed child.", "content": "New help for the severely retarded and emotionally disturbed child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221567"} {"pmid": "4221587", "title": "Essential hypertension. A twenty-year follow-up study.", "content": "Essential hypertension. A twenty-year follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221587"} {"pmid": "4221593", "title": "Helpful diagnostic clues for differentiation of atopic dermatitis from seborrheic dermatitis.", "content": "Helpful diagnostic clues for differentiation of atopic dermatitis from seborrheic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221593"} {"pmid": "4221597", "title": "Can pedodontics and orthodontics be combined in practice?", "content": "Can pedodontics and orthodontics be combined in practice?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221597"} {"pmid": "4221598", "title": "Pedodontic care for the deaf and blind.", "content": "Pedodontic care for the deaf and blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221598"} {"pmid": "4221599", "title": "Diabetes screening with Dextrostix in an industrial plant.", "content": "Diabetes screening with Dextrostix in an industrial plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221599"} {"pmid": "4221600", "title": "New AMWA president--1966.", "content": "New AMWA president--1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221600"} {"pmid": "4221604", "title": "The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods.", "content": "The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221604"} {"pmid": "4221605", "title": "Studies on swelling-shrinkage and oxidative phosphorylation of liver mitochondria of rat fed on 3'-methyl-4-dimethylaminoazobenzene.", "content": "Studies on swelling-shrinkage and oxidative phosphorylation of liver mitochondria of rat fed on 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221605"} {"pmid": "4221606", "title": "Biosynthesis of isovalthine.", "content": "Biosynthesis of isovalthine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221606"} {"pmid": "4221607", "title": "On the relation between the fatty acid composition and the swelling rate in rat liver mitochondria.", "content": "On the relation between the fatty acid composition and the swelling rate in rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221607"} {"pmid": "4221608", "title": "On the carbon origin of isovaleric acid residue of urinary isovalthine.", "content": "On the carbon origin of isovaleric acid residue of urinary isovalthine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221608"} {"pmid": "4221611", "title": "Growth of interorbital distance and skull thickness as observed in roentgenographic measurements.", "content": "Growth of interorbital distance and skull thickness as observed in roentgenographic measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221611"} {"pmid": "4221613", "title": "Ultrastructure of nasal scleroma (emphasizing the fine structure of Klebsiella rhinoscleromatis within the lesion).", "content": "Ultrastructure of nasal scleroma (emphasizing the fine structure of Klebsiella rhinoscleromatis within the lesion).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221613"} {"pmid": "4221616", "title": "Exchangeable water, sodium and chloride in the skin of mice.", "content": "Exchangeable water, sodium and chloride in the skin of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221616"} {"pmid": "4221614", "title": "Mechanism of melanophore dispersion. II. Stimulus-reaction-recovery and receptor problem.", "content": "Mechanism of melanophore dispersion. II. Stimulus-reaction-recovery and receptor problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221614"} {"pmid": "4221617", "title": "The effect of Sr2+ on swelling and ATP-linked contraction of mitochondria.", "content": "The effect of Sr2+ on swelling and ATP-linked contraction of mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221617"} {"pmid": "4221618", "title": "Endocrine effects on rat cardiac myofibrillar ATPase.", "content": "Endocrine effects on rat cardiac myofibrillar ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221618"} {"pmid": "4221610", "title": "A study of back cases in an outpatient clinic.", "content": "A study of back cases in an outpatient clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221610"} {"pmid": "4221609", "title": "Attempts to cultivate Mycobacterium lepraemurium in cell-free media.", "content": "Attempts to cultivate Mycobacterium lepraemurium in cell-free media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221609"} {"pmid": "4221622", "title": "Severe respiratory failure. The diagnosis and management of 37 cases.", "content": "Severe respiratory failure. The diagnosis and management of 37 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221622"} {"pmid": "4221623", "title": "Clinical relapse in early syphilis: unusual skin lesion following inadequate treatment.", "content": "Clinical relapse in early syphilis: unusual skin lesion following inadequate treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221623"} {"pmid": "4221626", "title": "A histochemical and electron microscopic study of skeletal muscle in a case of Pompe's disease (glycogenosis II).", "content": "A histochemical and electron microscopic study of skeletal muscle in a case of Pompe's disease (glycogenosis II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221626"} {"pmid": "4221627", "title": "Abdominal electromyography during micturition.", "content": "Abdominal electromyography during micturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221627"} {"pmid": "4221628", "title": "Heart size and prognosis in myocardial infarction.", "content": "Heart size and prognosis in myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221628"} {"pmid": "4221629", "title": "Dietary production of myocardial fibrosis in the rat.", "content": "Dietary production of myocardial fibrosis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221629"} {"pmid": "4221630", "title": "Clinical pathologic conference.", "content": "Clinical pathologic conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221630"} {"pmid": "4221633", "title": "Disability under Social Security: total-temporary impairments now entitled to benefits.", "content": "Disability under Social Security: total-temporary impairments now entitled to benefits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221633"} {"pmid": "4221634", "title": "Increase of serum beta-glucuronidase activity in human diabetes mellitus.", "content": "Increase of serum beta-glucuronidase activity in human diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221634"} {"pmid": "4221635", "title": "Intramyocardial lesions in patients dying suddenly and unexpectedly.", "content": "Intramyocardial lesions in patients dying suddenly and unexpectedly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221635"} {"pmid": "4221636", "title": "The handicapped child and the family.", "content": "The handicapped child and the family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221636"} {"pmid": "4221639", "title": "Thymidine incoporation into mammalian strain L-cells after the action of 5-fluorodoxyuridine and the effect of uracil.", "content": "Thymidine incoporation into mammalian strain L-cells after the action of 5-fluorodoxyuridine and the effect of uracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221639"} {"pmid": "4221638", "title": "Separation of adenosine triphosphatase of HK and LK sheep red cell membranes by density gradient centrifugation.", "content": "Separation of adenosine triphosphatase of HK and LK sheep red cell membranes by density gradient centrifugation. Membrane fragments from high potassium (HK) and low potassium (LK) sheep red cells were separated by density gradient centrifugation. Three preparations were studied: (1) HK membranes sonicated for 20 minutes, (2) HK membranes sonicated for 3 minutes, and (3) LK membranes sonicated for 3 minutes. The adenosine triphosphatase (ATPase) activity in the maximally disrupted preparation (1) was not sensitive to Na + K and was recovered in relatively small but heavy (specific gravity 1.19) fragments which made up no more than 8 per cent of the total membrane. Both Na + K-sensitive (S) and Na + K-insensitive (I) ATPase activity were found in the more gently broken up preparations (2) and (3) but the ratio of S- to I-ATPase was much greater in HK than in LK membrane fragments. S-ATPase activity in preparation (2) was about 50 per cent that observed in HK membranes prior to sonication. S-ATPase activity was recovered from the density gradient in relatively large but light (specific gravity 1.10) fragments. As was the case with the maximally disrupted preparation (1), I-ATPase activity in both preparations (2) and (3) was recovered in small but heavy (specific gravity > 1.20) fragments. The possibility that sensitivity of sheep red cell membrane ATPase to Na + K depends on the association between units containing the enzyme(s) and large, light, phospholipid-containing components is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221638"} {"pmid": "4221640", "title": "Let's dress the disabled for living.", "content": "Let's dress the disabled for living.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221640"} {"pmid": "4221641", "title": "Mongoloids, twins and tolerance.", "content": "Mongoloids, twins and tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221641"} {"pmid": "4221683", "title": "On the action of strophanthin G.", "content": "On the action of strophanthin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221683"} {"pmid": "4221682", "title": "Influences of protamine on the na+, K+-dependent ATPase and on the active transport processes of potassium and of L-DOPA into brain slices.", "content": "Influences of protamine on the na+, K+-dependent ATPase and on the active transport processes of potassium and of L-DOPA into brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221682"} {"pmid": "4221684", "title": "Connection between membrane adenosine triphosphatase activity and potassium transport in erythrocyte ghosts.", "content": "Connection between membrane adenosine triphosphatase activity and potassium transport in erythrocyte ghosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221684"} {"pmid": "4221685", "title": "Evaluation of the method of rivanol precipitation of [35S] sulphated mucopolysaccharides present in the material obtained from a small group of cells.", "content": "Evaluation of the method of rivanol precipitation of [35S] sulphated mucopolysaccharides present in the material obtained from a small group of cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221685"} {"pmid": "4221686", "title": "Connective and supporting tissues: mucopolysaccharides of connective tissues.", "content": "Connective and supporting tissues: mucopolysaccharides of connective tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221686"} {"pmid": "4221687", "title": "Chromosome abnormalities in a patient suffering from Huntington's chorea.", "content": "Chromosome abnormalities in a patient suffering from Huntington's chorea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221687"} {"pmid": "4221690", "title": "The care of the physically handicapped child.", "content": "The care of the physically handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221690"} {"pmid": "4221689", "title": "The effect of digitalis on the renal tubular transport of glucose in normal and in heartless dogs.", "content": "The effect of digitalis on the renal tubular transport of glucose in normal and in heartless dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221689"} {"pmid": "4221693", "title": "Granulopoiesis in Down's syndrome.", "content": "Granulopoiesis in Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221693"} {"pmid": "4221694", "title": "A new radiographic finding in mongolism.", "content": "A new radiographic finding in mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221694"} {"pmid": "4221697", "title": "Antimitotic action of cornin as a biologically active polypeptide. II. Physiological effects of cornin on dividing cell.", "content": "Antimitotic action of cornin as a biologically active polypeptide. II. Physiological effects of cornin on dividing cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221697"} {"pmid": "4221698", "title": "Immunochemical analysis of antigenic properties of human stomach cancer.", "content": "Immunochemical analysis of antigenic properties of human stomach cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221698"} {"pmid": "4221699", "title": "Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin.", "content": "Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221699"} {"pmid": "4221700", "title": "A histotopochemical study of the parathyroid gland of the albino rat.", "content": "A histotopochemical study of the parathyroid gland of the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221700"} {"pmid": "4221702", "title": "Acne: tetracyline or not?", "content": "Acne: tetracyline or not?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221702"} {"pmid": "4221705", "title": "The enzymic activity of the outer shell of Lactobacillus arabinosus.", "content": "The enzymic activity of the outer shell of Lactobacillus arabinosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221705"} {"pmid": "4221706", "title": "We're too fat.", "content": "We're too fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221706"} {"pmid": "4221707", "title": "What should we tell the patient?", "content": "What should we tell the patient?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221707"} {"pmid": "4221709", "title": "Brdicka serum filtrate reaction applied to normal and cancerous menstrual fluids.", "content": "Brdicka serum filtrate reaction applied to normal and cancerous menstrual fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221709"} {"pmid": "4221708", "title": "Obesity and the emotions.", "content": "Obesity and the emotions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221708"} {"pmid": "4221710", "title": "Diaphragmatic hernia in a premature infant.", "content": "Diaphragmatic hernia in a premature infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221710"} {"pmid": "4221711", "title": "Neurologic manifestations accompanying burns (burn encephalopathy).", "content": "Neurologic manifestations accompanying burns (burn encephalopathy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221711"} {"pmid": "4221712", "title": "Individuality of intellectual development.", "content": "Individuality of intellectual development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221712"} {"pmid": "4221713", "title": "The impact of disability on the child.", "content": "The impact of disability on the child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221713"} {"pmid": "4221714", "title": "The abnormal child: his impact on the family.", "content": "The abnormal child: his impact on the family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221714"} {"pmid": "4221715", "title": "Lack of correlation between natriuretic activity and inhibition of renal Nak-activated ATPase.", "content": "Lack of correlation between natriuretic activity and inhibition of renal Nak-activated ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221715"} {"pmid": "4221716", "title": "Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.", "content": "Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221716"} {"pmid": "4221717", "title": "Study of employment of 222 men with spinal cord injury.", "content": "Study of employment of 222 men with spinal cord injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221717"} {"pmid": "4221722", "title": "Golden anniversary--golden opportunity.", "content": "Golden anniversary--golden opportunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221722"} {"pmid": "4221723", "title": "Psychomotor abilities of familial, brain-injured and mongoloid retarded children.", "content": "Psychomotor abilities of familial, brain-injured and mongoloid retarded children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221723"} {"pmid": "4221724", "title": "The chances of reducing the incidence of skin infections of the newborn in a maternity hospital.", "content": "The chances of reducing the incidence of skin infections of the newborn in a maternity hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221724"} {"pmid": "4221727", "title": "Special clothing for the handicapped. Review of research and resources.", "content": "Special clothing for the handicapped. Review of research and resources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221727"} {"pmid": "4221729", "title": "Comparative antibiotic sensitivity studies in pustular acne vulgaris, 1954 and 1962.", "content": "Comparative antibiotic sensitivity studies in pustular acne vulgaris, 1954 and 1962.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221729"} {"pmid": "4221735", "title": "Problems of terminology in endocrinology.", "content": "Problems of terminology in endocrinology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221735"} {"pmid": "4221734", "title": "Studies on the effect of hypophysectomy and of partial hepatectomy on the aminoacid incorporating system from rat liver.", "content": "Studies on the effect of hypophysectomy and of partial hepatectomy on the aminoacid incorporating system from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221734"} {"pmid": "4221736", "title": "Regulation of protein synthesis: an alternative to the repressor-operator hypothesis.", "content": "Regulation of protein synthesis: an alternative to the repressor-operator hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221736"} {"pmid": "4221737", "title": "A radioautographic and radiometric analysis of the influence of parathyroid extract on the proline binding capacity of cultivated mouse radius rudiments.", "content": "A radioautographic and radiometric analysis of the influence of parathyroid extract on the proline binding capacity of cultivated mouse radius rudiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221737"} {"pmid": "4221739", "title": "Progressive brachycephalization: reproduction and headform in the Netherlands. A preliminary report.", "content": "Progressive brachycephalization: reproduction and headform in the Netherlands. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221739"} {"pmid": "4221738", "title": "Reflectometry of the skin in Dogons.", "content": "Reflectometry of the skin in Dogons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221738"} {"pmid": "4221740", "title": "\"Doubling\" of the palatal root in the second and third upper molars.", "content": "\"Doubling\" of the palatal root in the second and third upper molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221740"} {"pmid": "4221742", "title": "The deposition of radioactive Ba and Sr in the aortic wall.", "content": "The deposition of radioactive Ba and Sr in the aortic wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221742"} {"pmid": "4221743", "title": "Hemolymph protein and amino-acid composition as influenced by the corpus allatum in Locusta migratoria migratorioides (r. & f.).", "content": "Hemolymph protein and amino-acid composition as influenced by the corpus allatum in Locusta migratoria migratorioides (r. & f.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221743"} {"pmid": "4221744", "title": "Abdominal-wall hematomas.", "content": "Abdominal-wall hematomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221744"} {"pmid": "4221746", "title": "Acid mucopolysaccharides in electron microscopy. The use of the colloidal iron method.", "content": "Acid mucopolysaccharides in electron microscopy. The use of the colloidal iron method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221746"} {"pmid": "4221747", "title": "Phosphorus metabolism of intact crab nerve and its relation to the active transport of ions.", "content": "Phosphorus metabolism of intact crab nerve and its relation to the active transport of ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221747"} {"pmid": "4221748", "title": "A comparison of the phosphorus metabolism of intact squid nerve with that of the isolated axoplasm and sheath.", "content": "A comparison of the phosphorus metabolism of intact squid nerve with that of the isolated axoplasm and sheath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221748"} {"pmid": "4221751", "title": "S35 taurine metabolism in normal and mongoloid individuals.", "content": "S35 taurine metabolism in normal and mongoloid individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221751"} {"pmid": "4221752", "title": "Concentrations of uric acid in the sweat of control and mongoloid children.", "content": "Concentrations of uric acid in the sweat of control and mongoloid children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221752"} {"pmid": "4221753", "title": "Histochemical and histoenzymological studies on the growing cartilage in the Turner's syndrome.", "content": "Histochemical and histoenzymological studies on the growing cartilage in the Turner's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221753"} {"pmid": "4221754", "title": "Congenital malformations produced in chickens by fluorinated pyrimidines.", "content": "Congenital malformations produced in chickens by fluorinated pyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221754"} {"pmid": "4221755", "title": "Massive neurofibrosarcoma of the anterior abdominal wall.", "content": "Massive neurofibrosarcoma of the anterior abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221755"} {"pmid": "4221756", "title": "Notes from a visit to the Soviet Union: treatments and studies of alcoholism; education about alcohol; drinking in Georgia.", "content": "Notes from a visit to the Soviet Union: treatments and studies of alcoholism; education about alcohol; drinking in Georgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221756"} {"pmid": "4221758", "title": "IUPAC-iub Commission on Biochemical Nomenclature. Tentative rules. Trivial names of miscellaneous compounds of importance in biochemistry.", "content": "IUPAC-iub Commission on Biochemical Nomenclature. Tentative rules. Trivial names of miscellaneous compounds of importance in biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221758"} {"pmid": "4221759", "title": "Experimental tetracycline labeling in avian osteopetrosis.", "content": "Experimental tetracycline labeling in avian osteopetrosis. Osteopetrosis was experimentally produced and lesion development in time was studied by fluorescent illumination of tetracycline labels in the bone. Bones from birds 84, 115, 186 and 354 days of age were examined by ground section under ultraviolet light. Periosteal activity of the tibia and femur was present in normal bones at 84 days of age but had stopped at 115 days. Focal periosteal activity of osteopetrotic lesions was present at 186 days but not at 354 days of age. Slight endosteal activity of osteopetrotic bones was present at 354 days of age. Osteopetrotic bone formed at a rate of 1.26 mm. per week or 6 times faster than normal bone in some of these lesions. Tetracycline diffused throughout the 354-day-old osteopetrotic lesion but not normal compact bone indicating that the osteopetrotic bone is porous and spongy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221759"} {"pmid": "4221760", "title": "Amyloidosis in captive anseriformes.", "content": "Amyloidosis in captive anseriformes. During the period 1945-1962, percentage deaths of anserine birds (ducks, geese and swans) did not vary remarkably from year to year even though the population has more than quadrupled during the same period. The number of deaths with amyloidosis has increased significantly even though the death rate did not change. The number of deaths due to tuberculosis, mould, renal diseases, hepatitis and infection accompanied by amyloidosis also increased, especially during the second half the study period. Cases of known secondary amyloidosis accounted for 71.4% whereas 28.6% of the remaining cases were classified as \"doubtfully\" primary. Sites of deposition amyloid in the two categories were the same and it has never been observed in the heart. The amyloid deposits in the birds did not differ from those in man when examined by number of histochemical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221760"} {"pmid": "4221761", "title": "Surface temperatures of avian osteopetrotic bones.", "content": "Surface temperatures of avian osteopetrotic bones. Body temperatures and surface temperatures of metatarsal bones were recorded in normal and osteopetrotic chickens. Osteopetrotic lesions were 6.5 F warmer than normal bones but there was no corresponding increase in body temperature at a given environmental temperature. This indicates that the temperature elevation in the osteopetrotic lesion is a local phenomenon and not a systemic response. This also supports earlier observations that osteopetrotic bones feel warmer to the touch than normal bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221761"} {"pmid": "4221762", "title": "Production of antibodies in the mammary gland with especial reference to virus neutralizing antibody.", "content": "Production of antibodies in the mammary gland with especial reference to virus neutralizing antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221762"} {"pmid": "4221766", "title": "Volunteers blaze a trail.", "content": "Volunteers blaze a trail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221766"} {"pmid": "4221767", "title": "Down's syndrome with unusual karyotype and thyroid autoantibodies.", "content": "Down's syndrome with unusual karyotype and thyroid autoantibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221767"} {"pmid": "4221771", "title": "Enzyme activities and maximal rates of glycolysis in anaerobic myocardium.", "content": "Enzyme activities and maximal rates of glycolysis in anaerobic myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221771"} {"pmid": "4221772", "title": "A comparison of two antiseptic and steroid creams, illustrating the importance of an \"order effect\" in such trials.", "content": "A comparison of two antiseptic and steroid creams, illustrating the importance of an \"order effect\" in such trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221772"} {"pmid": "4221773", "title": "Genetic interference and recombination in phage T4: the role of heterozygotes.", "content": "Genetic interference and recombination in phage T4: the role of heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221773"} {"pmid": "4221774", "title": "Study of mechanisms which preserve blood fluidity and the effect of their inhibition on thrombogenesis.", "content": "Study of mechanisms which preserve blood fluidity and the effect of their inhibition on thrombogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221774"} {"pmid": "4221776", "title": "Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.", "content": "Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221776"} {"pmid": "4221778", "title": "The halt and the whole: thoughts on adaptation.", "content": "The halt and the whole: thoughts on adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221778"} {"pmid": "4221777", "title": "The use of metabolic inhibitors in studies on the mode of replication of vaccinia virus.", "content": "The use of metabolic inhibitors in studies on the mode of replication of vaccinia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221777"} {"pmid": "4221779", "title": "Combined oral, topical and surgical treatment of onychomycosis.", "content": "Combined oral, topical and surgical treatment of onychomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221779"} {"pmid": "4221780", "title": "Improved griseofulvin therapy for tinea pedis.", "content": "Improved griseofulvin therapy for tinea pedis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221780"} {"pmid": "4221781", "title": "The mechanism of calcium and magnesium uptake from sea water by a marine bacterium.", "content": "The mechanism of calcium and magnesium uptake from sea water by a marine bacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221781"} {"pmid": "4221782", "title": "Backache in industry.", "content": "Backache in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221782"} {"pmid": "4221783", "title": "Civil actions for damages versus workmen's compensation benefits.", "content": "Civil actions for damages versus workmen's compensation benefits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221783"} {"pmid": "4221784", "title": "Management of atopic dermatitis.", "content": "Management of atopic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221784"} {"pmid": "4221785", "title": "Office management of acne vulgaris.", "content": "Office management of acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221785"} {"pmid": "4221786", "title": "Hexosamine content of callus tissue.", "content": "Hexosamine content of callus tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221786"} {"pmid": "4221788", "title": "A multidisciplined evaluation clinic for the child with a handicap. A summary of the first year's activities.", "content": "A multidisciplined evaluation clinic for the child with a handicap. A summary of the first year's activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221788"} {"pmid": "4221789", "title": "Biochemical properties of anti-inflammatory drugs. VI. The effects of chloroquine (resochin), mepacrine (quinacrine) and some of their potential metabolites on cartilage metabolism and oxidative phosphorylation.", "content": "Biochemical properties of anti-inflammatory drugs. VI. The effects of chloroquine (resochin), mepacrine (quinacrine) and some of their potential metabolites on cartilage metabolism and oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221789"} {"pmid": "4221790", "title": "Biochemical study of anti-inflammatory and anti-arthritic properties of glycyrrhetic acid.", "content": "Biochemical study of anti-inflammatory and anti-arthritic properties of glycyrrhetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221790"} {"pmid": "4221791", "title": "Molecular mechanisms of genetic recombination of bacteriophage. V. Two kinds of joining of parental DNA molecules.", "content": "Molecular mechanisms of genetic recombination of bacteriophage. V. Two kinds of joining of parental DNA molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221791"} {"pmid": "4221819", "title": "A model illustrating some aspects of muscle spindle physiology.", "content": "A model illustrating some aspects of muscle spindle physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221819"} {"pmid": "4221821", "title": "Diagnosis and surgical correction of combined congenital defects of supra-umbilical abdominal wall, lower sternum, and diaphragm.", "content": "Diagnosis and surgical correction of combined congenital defects of supra-umbilical abdominal wall, lower sternum, and diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221821"} {"pmid": "4221820", "title": "Studies on the adenosine triphosphatase, calcium uptake and relaxing activity of the microsomal granules from skeletal muscle.", "content": "Studies on the adenosine triphosphatase, calcium uptake and relaxing activity of the microsomal granules from skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221820"} {"pmid": "4221825", "title": "Effect of different steroids on lactating rats.", "content": "Effect of different steroids on lactating rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221825"} {"pmid": "4221826", "title": "An effect of growth hormone on hexose phosphate metabolism.", "content": "An effect of growth hormone on hexose phosphate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221826"} {"pmid": "4221827", "title": "Identification of a cytopathogenic agent infectious for puppies as a canine herpesvirus.", "content": "Identification of a cytopathogenic agent infectious for puppies as a canine herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221827"} {"pmid": "4221828", "title": "Effect of diisopropyl fluorophosphate on gastric secretion and gastric ATPase.", "content": "Effect of diisopropyl fluorophosphate on gastric secretion and gastric ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221828"} {"pmid": "4221829", "title": "Stimulation of erythrocyte glycolysis by nicotinamide adenylates.", "content": "Stimulation of erythrocyte glycolysis by nicotinamide adenylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221829"} {"pmid": "4221830", "title": "In vitro inhibition of Na+-K+ and Mg2+ ATPases by mono, di and trivalent cations.", "content": "In vitro inhibition of Na+-K+ and Mg2+ ATPases by mono, di and trivalent cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221830"} {"pmid": "4221823", "title": "Eruption of teeth through the oral mucosa.", "content": "Eruption of teeth through the oral mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221823"} {"pmid": "4221834", "title": "Immunological study of rabbit cysticercosis. I. The suitability of agar gel diffusion precipitation and indirect haemagglutination tests.", "content": "Immunological study of rabbit cysticercosis. I. The suitability of agar gel diffusion precipitation and indirect haemagglutination tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221834"} {"pmid": "4221837", "title": "Correction of the von Krogh equation.", "content": "Correction of the von Krogh equation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221837"} {"pmid": "4221838", "title": "Studies on biochemical and metabolic changes of rat and guinea-pig skin following congelation.", "content": "Studies on biochemical and metabolic changes of rat and guinea-pig skin following congelation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221838"} {"pmid": "4221839", "title": "Hormone assay studies in patients with anorexia nervosa.", "content": "Hormone assay studies in patients with anorexia nervosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221839"} {"pmid": "4221841", "title": "Preparation--properties of A Na+ + K+-activated MgATPase in the rabbit auricle.", "content": "Preparation--properties of A Na+ + K+-activated MgATPase in the rabbit auricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221841"} {"pmid": "4221840", "title": "The protective influence of substances upon the antimitotic effect of epinephrine and its metabolites in human cell cultures.", "content": "The protective influence of substances upon the antimitotic effect of epinephrine and its metabolites in human cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221840"} {"pmid": "4221842", "title": "Interactions of positive inotropic agents and metabolites on the rat ventricle strip.", "content": "Interactions of positive inotropic agents and metabolites on the rat ventricle strip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221842"} {"pmid": "4221845", "title": "Brow presentation.", "content": "Brow presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221845"} {"pmid": "4221843", "title": "Medical treatment of hypertension.", "content": "Medical treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221843"} {"pmid": "4221844", "title": "Study of the UV-induction of mutations in bacteria.", "content": "Study of the UV-induction of mutations in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221844"} {"pmid": "4221846", "title": "Iatrogenic acute anemia: primaquine sensitivity.", "content": "Iatrogenic acute anemia: primaquine sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221846"} {"pmid": "4221847", "title": "Hepatitis.", "content": "Hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221847"} {"pmid": "4221848", "title": "Renal glycosuria.", "content": "Renal glycosuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221848"} {"pmid": "4221849", "title": "A simulation study of mammalian phosphofructokinase.", "content": "A simulation study of mammalian phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221849"} {"pmid": "4221850", "title": "The glycosaminoglycans of the early stage of fracture repair.", "content": "The glycosaminoglycans of the early stage of fracture repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221850"} {"pmid": "4221851", "title": "The glycosaminoglycans in a pseudarthrosis femoris.", "content": "The glycosaminoglycans in a pseudarthrosis femoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221851"} {"pmid": "4221854", "title": "Common nondiscogenic back disorders.", "content": "Common nondiscogenic back disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221854"} {"pmid": "4221855", "title": "What every doctor should know about workmen's compensation.", "content": "What every doctor should know about workmen's compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221855"} {"pmid": "4221860", "title": "The radiological manifestations of the initial phases of rheumatic carditis in childhood.", "content": "The radiological manifestations of the initial phases of rheumatic carditis in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221860"} {"pmid": "4221853", "title": "Dental care for the special patient. (Handicapped--chronically ill--aged).", "content": "Dental care for the special patient. (Handicapped--chronically ill--aged).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221853"} {"pmid": "4221861", "title": "Diaphragm movements and the diagnosis of diaphragmatic paralysis.", "content": "Diaphragm movements and the diagnosis of diaphragmatic paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221861"} {"pmid": "4221863", "title": "The use of short-induction nitrous oxide and oxygen with penthrane; a new concept in pediatric oral surgical anesthesia.", "content": "The use of short-induction nitrous oxide and oxygen with penthrane; a new concept in pediatric oral surgical anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221863"} {"pmid": "4221862", "title": "An investigation by electron microscopy of the nucleoside phosphatase activity of amphibian and mammalian erythrocytes.", "content": "An investigation by electron microscopy of the nucleoside phosphatase activity of amphibian and mammalian erythrocytes. Amphibian and mammalian blood was washed in isotonic saline, fixed in glutaraldehyde, and then stained in the ATPase medium of Wachstein and Meisel. The blood cells were subsequently postfixed in osmium tetroxide, embedded in epoxy resins, and studied by electron microscopy. The plasma membranes of amphibian erythrocytes, from the newt Triturus cristatus and the frog Rana esculenta, were stained after incubation in media containing ATP or ADP as substrates, but were unstained after incubation in media containing AMP or sodium beta-glycerophosphate. The addition of 0.001 M ouabain to ATP-containing media did not inhibit the staining of the plasma membranes, but the omission of Mg(++) ions from the medium inhibited staining. The plasma membranes of rat and rabbit erythrocytes were never stained after incubation in any of the media used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221862"} {"pmid": "4221870", "title": "Treatment of acne vulgaris with Secomat -S lotion.", "content": "Treatment of acne vulgaris with Secomat -S lotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221870"} {"pmid": "4221871", "title": "Staphylococcal enterotoxin.", "content": "Staphylococcal enterotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221871"} {"pmid": "4221872", "title": "Biological attributes of staphylococcal cell walls.", "content": "Biological attributes of staphylococcal cell walls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221872"} {"pmid": "4221873", "title": "Observations of the staphylococcal nasal carrier state.", "content": "Observations of the staphylococcal nasal carrier state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221873"} {"pmid": "4221874", "title": "Patterns of transmission of staphylococci.", "content": "Patterns of transmission of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221874"} {"pmid": "4221875", "title": "Intracellular phosphate release by the Na+-K+-activated membrane ATPase.", "content": "Intracellular phosphate release by the Na+-K+-activated membrane ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221875"} {"pmid": "4221876", "title": "Reduction of dynamic sensitivity of primary muscle spindle endings in experimental tremor.", "content": "Reduction of dynamic sensitivity of primary muscle spindle endings in experimental tremor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221876"} {"pmid": "4221877", "title": "A method for turbidimetric measurement of heparin: its application to the estimation of heparin in aortic tissue.", "content": "A method for turbidimetric measurement of heparin: its application to the estimation of heparin in aortic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221877"} {"pmid": "4221878", "title": "Aortic acid mucopolysaccharides and collagen in scorbutic guinea pigs.", "content": "Aortic acid mucopolysaccharides and collagen in scorbutic guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221878"} {"pmid": "4221882", "title": "Increase in uric acid biosynthesis produced by 2-substituted thiadiazoles.", "content": "Increase in uric acid biosynthesis produced by 2-substituted thiadiazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221882"} {"pmid": "4221883", "title": "Separation and characterization of delta-5-3-hydroxy-C19-steroids by thin-layer chromatography.", "content": "Separation and characterization of delta-5-3-hydroxy-C19-steroids by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221883"} {"pmid": "4221887", "title": "Management of skin problems in the adolescent.", "content": "Management of skin problems in the adolescent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221887"} {"pmid": "4221888", "title": "Chemical analysis and biological activities of fatty acids from the liver of x-ray irradiated rabbit, the antitumor agent so-called OX.", "content": "Chemical analysis and biological activities of fatty acids from the liver of x-ray irradiated rabbit, the antitumor agent so-called OX.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221888"} {"pmid": "4221890", "title": "Mechanism of induction of anisocytosis.", "content": "Mechanism of induction of anisocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221890"} {"pmid": "4221891", "title": "Cellular antibody in mice bearing Ehrlich cancer. I. A quantitative study on antitumor activity of cellular antibody in vitro.", "content": "Cellular antibody in mice bearing Ehrlich cancer. I. A quantitative study on antitumor activity of cellular antibody in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221891"} {"pmid": "4221884", "title": "Acid mucopolysaccharides in the oral epithelium.", "content": "Acid mucopolysaccharides in the oral epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221884"} {"pmid": "4221893", "title": "Cytochemical studies of adenosine triphosphatase activity in the sarcoplasmic reticulum.", "content": "Cytochemical studies of adenosine triphosphatase activity in the sarcoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221893"} {"pmid": "4221895", "title": "Factors influencing activation of phosphofructokinase.", "content": "Factors influencing activation of phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221895"} {"pmid": "4221896", "title": "Unbelievable medico-legal adjudications.", "content": "Unbelievable medico-legal adjudications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221896"} {"pmid": "4221897", "title": "The influence of heating on the morphology and photochemical activity of isolated chloroplasts.", "content": "The influence of heating on the morphology and photochemical activity of isolated chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221897"} {"pmid": "4221898", "title": "Preparation of rabbit muscle myosin or actomyosin free of 5'-adenylic acid deaminase.", "content": "Preparation of rabbit muscle myosin or actomyosin free of 5'-adenylic acid deaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221898"} {"pmid": "4221899", "title": "The effect of lipids on enzyme levels in beating rat heart cells.", "content": "The effect of lipids on enzyme levels in beating rat heart cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221899"} {"pmid": "4221900", "title": "Left ventricular hypertrophy in chronic bronchitis.", "content": "Left ventricular hypertrophy in chronic bronchitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221900"} {"pmid": "4221906", "title": "The Graham-Steell murmur re-evaluated.", "content": "The Graham-Steell murmur re-evaluated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221906"} {"pmid": "4221909", "title": "Extracts from a lecture delivered by A. Withnell, Esq., B.Sc., M.D., D.P.H. to dental surgery assistants in the employment of the Staffordshire County Council School's Health Service.", "content": "Extracts from a lecture delivered by A. Withnell, Esq., B.Sc., M.D., D.P.H. to dental surgery assistants in the employment of the Staffordshire County Council School's Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221909"} {"pmid": "4221908", "title": "Anomalies of the origin of coronary arteries. (Special reference to single coronary artery).", "content": "Anomalies of the origin of coronary arteries. (Special reference to single coronary artery).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221908"} {"pmid": "4221910", "title": "Hog cholera. V. Demonstration of the antigen in swine tissues by the fluorescent antibody technique.", "content": "Hog cholera. V. Demonstration of the antigen in swine tissues by the fluorescent antibody technique. The fluorescent antibody technique was employed to detect hog cholera virus in tissue sections of various organs from experimentally infected swine. The method proved to be highly sensitive and infection could be detected in these animals as early as three days after inoculation with the virus. Best results were obtained when tissues were collected from young animals in advanced disease rather than from sows or from pigs in the early febrile phase. Tonsil, spleen and lymph node were the tissues of choice and were most satisfactory when removed from freshly killed animals rather than from those that had died.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221910"} {"pmid": "4221911", "title": "Progressive myelopathy in a dog caused by thorium dioxide.", "content": "Progressive myelopathy in a dog caused by thorium dioxide. A study of the use of Thorotrast as a contrast media in myelograms in dogs is presented, indicating that the material introduced into the cerebro-spinal fluid, will become permanently associated with the meninges, leading to the development of myelopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221911"} {"pmid": "4221912", "title": "The physiopathological changes in synovial fluid in arthritic swine.", "content": "The physiopathological changes in synovial fluid in arthritic swine. There was produced with Ery. rhusiopathiae a rheumatoid-like arthritis in swine, which passed successively through acute, sub-acute and chronic stages. This was typically a non-suppurative proliferative change with concurrent changes in the joint fluid. The arthritis was shown to persist even though the initial inciting agent could not be isolated from the advanced cases of chronic polyarthritis. This strongly suggests that the pathological process responsible for this arthritis can become autonomic and probably is related to a state of hypersensitivity. The cellular changes observed in the synovial fluid did not differ markedly from those of rheumatoid arthritis in man. Synovial fluid mucinous changes were apparent in the decreased viscosity observed grossly. Definite changes in the character of the precipitate produced by acetic acid treatment of the fluid were also observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221912"} {"pmid": "4221913", "title": "Observations on a swine herd health program.", "content": "Observations on a swine herd health program. Observations on a swine herd health program are reported. A primary purpose was to show that such programs could provide economic benefits to swine breeders and sources for breeding stock of minimum disease status. The possible influence of diseases of swine, including atrophic rhinitis and virus pneumonia, on both aspects are discussed. The inadequacy of knowledge of diseases of swine, both specifically and generally, is pointed out. Veterinary supervision of a swine herd will result in economic benefits to an average capable owner. There is both merit and need for such programs, but as to what health standards would be reasonable, practical, and meaningful, is still not clearly defined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221913"} {"pmid": "4221919", "title": "Abnormal bleeding conditions in urologic patients.", "content": "Abnormal bleeding conditions in urologic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221919"} {"pmid": "4221921", "title": "Brachial artery puncture: an oft neglected clinical tool in the evaluation of hypertension.", "content": "Brachial artery puncture: an oft neglected clinical tool in the evaluation of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221921"} {"pmid": "4221920", "title": "Gas gangrene infection: combined treatment including 3,432,000 international units of polyvalent gas gangrene antitoxin.", "content": "Gas gangrene infection: combined treatment including 3,432,000 international units of polyvalent gas gangrene antitoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221920"} {"pmid": "4221922", "title": "Carcinoma of the tongue: the role of chronic irritation.", "content": "Carcinoma of the tongue: the role of chronic irritation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221922"} {"pmid": "4221924", "title": "Studies on reticuloendothelial system and hemaotpoiesis. I. Studies of extramedullary hematopoiesis.", "content": "Studies on reticuloendothelial system and hemaotpoiesis. I. Studies of extramedullary hematopoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221924"} {"pmid": "4221925", "title": "The appearance of perinucleolar halos in cultured cells with 5-fluorouracil.", "content": "The appearance of perinucleolar halos in cultured cells with 5-fluorouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221925"} {"pmid": "4221926", "title": "Neotetrazolium salt (NT) as an electron acceptor in living cell: a study on the JTC-3 and HeLa cells in culture.", "content": "Neotetrazolium salt (NT) as an electron acceptor in living cell: a study on the JTC-3 and HeLa cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221926"} {"pmid": "4221927", "title": "A histochemical study on the structural differences of motor endplate in the red, white and intermediate muscle fibers of mouse limb muscle.", "content": "A histochemical study on the structural differences of motor endplate in the red, white and intermediate muscle fibers of mouse limb muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221927"} {"pmid": "4221929", "title": "Heart weight of Jamaicans. Autopsy study of normal cases and cases of hypertension and chronic lung disease.", "content": "Heart weight of Jamaicans. Autopsy study of normal cases and cases of hypertension and chronic lung disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221929"} {"pmid": "4221928", "title": "On the relationship of vascular wall and connective tissue. Histological, immunological and radiochemical investigations.", "content": "On the relationship of vascular wall and connective tissue. Histological, immunological and radiochemical investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221928"} {"pmid": "4221930", "title": "Analysis of experience in workmen's compensation for heart cases. Factors influencing the decision re compensability in heart attacks occurring among industrial workers.", "content": "Analysis of experience in workmen's compensation for heart cases. Factors influencing the decision re compensability in heart attacks occurring among industrial workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221930"} {"pmid": "4221932", "title": "You take him as you find him.", "content": "You take him as you find him.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221932"} {"pmid": "4221936", "title": "Severe mucocutaneous and systemic reactions to drugs occurring in five patients during treatment for pulmonary tuberculosis.", "content": "Severe mucocutaneous and systemic reactions to drugs occurring in five patients during treatment for pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221936"} {"pmid": "4221937", "title": "A comprehensive care program for children with handicaps.", "content": "A comprehensive care program for children with handicaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221937"} {"pmid": "4221938", "title": "The \"D\" syndrome. Report of four trisomic and one D/D translocation case.", "content": "The \"D\" syndrome. Report of four trisomic and one D/D translocation case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221938"} {"pmid": "4221939", "title": "Morphological Philadelphia chromosome. Occurrence in a child with congenital anomalies.", "content": "Morphological Philadelphia chromosome. Occurrence in a child with congenital anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221939"} {"pmid": "4221940", "title": "Hepatic ultrastructure in the Hurler syndrome.", "content": "Hepatic ultrastructure in the Hurler syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221940"} {"pmid": "4221941", "title": "Formal discussion: future prospects in leukemia chemotherapy.", "content": "Formal discussion: future prospects in leukemia chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221941"} {"pmid": "4221943", "title": "Phytohaemagglutinin on maternal and umbilical leukocytes.", "content": "Phytohaemagglutinin on maternal and umbilical leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221943"} {"pmid": "4221944", "title": "Cellular antibody in mice bearing Ehrlich cancer. II. Properties of lymphoid cells from sensitized animal.", "content": "Cellular antibody in mice bearing Ehrlich cancer. II. Properties of lymphoid cells from sensitized animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221944"} {"pmid": "4221946", "title": "Connotative reactions of college students to disability labels.", "content": "Connotative reactions of college students to disability labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221946"} {"pmid": "4221948", "title": "The control system governing bone growth in response to mechanical stress.", "content": "The control system governing bone growth in response to mechanical stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221948"} {"pmid": "4221947", "title": "Tuning forks. A diagnostic aid in hearing loss.", "content": "Tuning forks. A diagnostic aid in hearing loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221947"} {"pmid": "4221949", "title": "A history of the therapy of angina pectoris.", "content": "A history of the therapy of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221949"} {"pmid": "4221950", "title": "Battered child syndrome.", "content": "Battered child syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221950"} {"pmid": "4221951", "title": "Carcinoma of the cervix in young women.", "content": "Carcinoma of the cervix in young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221951"} {"pmid": "4221952", "title": "Obstruction of the superior vena cava.", "content": "Obstruction of the superior vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221952"} {"pmid": "4221953", "title": "Dissociation of a complex of F-actin and H-meromyosin by addition of adenosine triphosphate.", "content": "Dissociation of a complex of F-actin and H-meromyosin by addition of adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221953"} {"pmid": "4221956", "title": "Biophysical and biochemical studies of healing fractures, with special reference to glycoaminoglycans.", "content": "Biophysical and biochemical studies of healing fractures, with special reference to glycoaminoglycans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221956"} {"pmid": "4221961", "title": "Cardiovascular abnormalities in infants malnourished before birth.", "content": "Cardiovascular abnormalities in infants malnourished before birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221961"} {"pmid": "4221962", "title": "Dental and facial characteristics in Down's syndrome. (Mongolism).", "content": "Dental and facial characteristics in Down's syndrome. (Mongolism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221962"} {"pmid": "4221964", "title": "Management of crushed chest injuries.", "content": "Management of crushed chest injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221964"} {"pmid": "4221965", "title": "The radioisotope blood pool scan.", "content": "The radioisotope blood pool scan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221965"} {"pmid": "4221966", "title": "Evaluation of rehabilitation in home or clinic setting: problems in methodology.", "content": "Evaluation of rehabilitation in home or clinic setting: problems in methodology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221966"} {"pmid": "4221954", "title": "Histochemical studies on the adrenal medullary cells of the marmoset (Callithrix jacchus).", "content": "Histochemical studies on the adrenal medullary cells of the marmoset (Callithrix jacchus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221954"} {"pmid": "4221955", "title": "Suggestions for a histochemical terminology of carbohydrate-rich tissue components.", "content": "Suggestions for a histochemical terminology of carbohydrate-rich tissue components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221955"} {"pmid": "4221969", "title": "The yaws elimination campaign in Malaya.", "content": "The yaws elimination campaign in Malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221969"} {"pmid": "4221971", "title": "The rehabilitation of severely disabled boys.", "content": "The rehabilitation of severely disabled boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221971"} {"pmid": "4221970", "title": "University education and personality problems of undergraduates.", "content": "University education and personality problems of undergraduates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221970"} {"pmid": "4221972", "title": "A report of the incidence of positive tuberculosis skin test reactors and the incidence of active Tuberculosis among school children in the Methodist schools, Kapit district, Sarawak, Malaysia.", "content": "A report of the incidence of positive tuberculosis skin test reactors and the incidence of active Tuberculosis among school children in the Methodist schools, Kapit district, Sarawak, Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221972"} {"pmid": "4221973", "title": "Investigation of ophthalmological conditions in Kelantan.", "content": "Investigation of ophthalmological conditions in Kelantan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221973"} {"pmid": "4221975", "title": "A rapid method for the identification of Candida albicans by the use of a serum--glucose preparation.", "content": "A rapid method for the identification of Candida albicans by the use of a serum--glucose preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221975"} {"pmid": "4221974", "title": "A comparative epidemiologic study of fractures among Indian, Malay and Swedish children.", "content": "A comparative epidemiologic study of fractures among Indian, Malay and Swedish children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221974"} {"pmid": "4221976", "title": "Uric acid diathesis as met with in Kuala Kangsar district hospital.", "content": "Uric acid diathesis as met with in Kuala Kangsar district hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221976"} {"pmid": "4221960", "title": "Religion and physical disability.", "content": "Religion and physical disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221960"} {"pmid": "4221977", "title": "Human and veterinary medicine.", "content": "Human and veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221977"} {"pmid": "4221978", "title": "The role of the pharmacist in the community.", "content": "The role of the pharmacist in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221978"} {"pmid": "4221983", "title": "MEND, a rehabilitation program.", "content": "MEND, a rehabilitation program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221983"} {"pmid": "4221985", "title": "An energy-dependent hydrogen-evolution from dithionite in nitrogen-fixing extracts of Clostridium pasteurianum.", "content": "An energy-dependent hydrogen-evolution from dithionite in nitrogen-fixing extracts of Clostridium pasteurianum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221985"} {"pmid": "4221987", "title": "Symptoms and pathology produced by toxic Microcystis aeruginosa NRC-1 in laboratory and domestic animals.", "content": "Symptoms and pathology produced by toxic Microcystis aeruginosa NRC-1 in laboratory and domestic animals. Toxicity tests with lyophilized M. aeruginosa NRC-1 cells have been conducted using mice, guinea pigs, rabbits, chickens, ducks, two calves and one lamb as the test animals. The symptoms and pathological changes are described. On an equivalent weight basis it required three to five times the oral dosage to kill the large animals and birds as it did to kill the laboratory animals. The symptoms were less pronounced and the survival times were longer in the more resistant animals. Enlargement and congestion of the liver with necrosis of the hepatic cells were constant and pathognomonic. These findings are in general agreement with the observations of other workers who have examined the toxicity of naturally occurring Microcystis waterblooms. The toxicities and structures of microcystin and of six other biologically active cyclic polypeptides are summarized. The pathological effects produced by microcystin in laboratory and domestic animals resemble those produced in man but differ from those produced in animals by the toxic peptides of Amanita phalloides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221987"} {"pmid": "4221986", "title": "Effects of parathyroid hormone and other proteins in vitro on mitochondrial metabolism.", "content": "Effects of parathyroid hormone and other proteins in vitro on mitochondrial metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221986"} {"pmid": "4221988", "title": "Preliminary bluetongue Transmission with the sheep ked Melophagus ovinus (L.).", "content": "Preliminary bluetongue Transmission with the sheep ked Melophagus ovinus (L.). Five experiments indicated that the sheep ked MELOPHAGUS OVINUS (L.), can transmit bluetongue virus (BTV) in sheep. It was not determined whether these were mechanical or biological transmissions, although the results suggested mechanical transmission. Sheep keds were manually transferred from a BTV-host sheep to 18 susceptible test sheep. Of these, 10 were positive (5 with mild reactions), 6 questionable, and 2 negative for BTV. Three of the mildly reacting sheep and 3 of the questionable sheep had highly intensified reactions on challenge inoculation. Five of the positive sheep were immune on challenge inoculation. Blood from 2 positive reactors was subpassaged into susceptible sheep, which reacted with typical disease signs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221988"} {"pmid": "4221989", "title": "Epithelial inclusions of a bovine heart.", "content": "Epithelial inclusions of a bovine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221989"} {"pmid": "4221991", "title": "Microbiological transformations of terpenes. VI. Studies on the mechanism of some fungal hydroxylation reactions with the aid of model systems.", "content": "Microbiological transformations of terpenes. VI. Studies on the mechanism of some fungal hydroxylation reactions with the aid of model systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221991"} {"pmid": "4221990", "title": "Hog cholera IV. Detection of the virus in tissue culture preparations by the fluorescent antibody technique.", "content": "Hog cholera IV. Detection of the virus in tissue culture preparations by the fluorescent antibody technique. The fluorescent-antibody technique was employed for detection of hog cholera virus in tissue cultures inoculated with spleens of infected animals. As controls, cultures were also inoculated with material from normal swine and from those infected with other agents. In the first series 71 of 73 infected spleens, or 97 per cent, were detected. There were no false positive reactions among the controls. Results obtained with the second series of pigs showed that spleens collected during advanced stages of the disease were more satisfactory specimens than those collected earlier during the high temperature phase of infection. Findings with the third series of older swine indicated that their spleens were less satisfactory as a source of virus than those from young pigs. Tissues from freshly killed animals provided better specimen material than those from animals which had died.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221990"} {"pmid": "4221992", "title": "Bacterial metabolism of hydroxyproline. I. Metabolism of L-allohydroxyproline by a Pseudomonas.", "content": "Bacterial metabolism of hydroxyproline. I. Metabolism of L-allohydroxyproline by a Pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221992"} {"pmid": "4221993", "title": "Bacterial metabolism of hydroxyproline. II. Metabolism of L-hydroxyproline in Achromobacter.", "content": "Bacterial metabolism of hydroxyproline. II. Metabolism of L-hydroxyproline in Achromobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221993"} {"pmid": "4221984", "title": "An occupational therapist's role in oral hygiene for the handicapped.", "content": "An occupational therapist's role in oral hygiene for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221984"} {"pmid": "4221994", "title": "Distribution of alpha-glucosidase activities in human & monkey small intestine.", "content": "Distribution of alpha-glucosidase activities in human & monkey small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221994"} {"pmid": "4221995", "title": "Synthesis of serum proteins in carbon tetrachloride injured rat & effect of vitamin B12 protection.", "content": "Synthesis of serum proteins in carbon tetrachloride injured rat & effect of vitamin B12 protection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221995"} {"pmid": "4221996", "title": "Incorporation of orotic acid-14C in a logarithmically growing culture of Escherichia coli.", "content": "Incorporation of orotic acid-14C in a logarithmically growing culture of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221996"} {"pmid": "4221997", "title": "A critical study of the conditions for colorimetric estimation of serum transaminases. I. Estimation of small amounts of pyruvic acid in the presence of ketoglutarate using dinitrophenylhydrazine.", "content": "A critical study of the conditions for colorimetric estimation of serum transaminases. I. Estimation of small amounts of pyruvic acid in the presence of ketoglutarate using dinitrophenylhydrazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221997"} {"pmid": "4221998", "title": "Changes in the composition of striated muscle proteins of rat at different stages after birth.", "content": "Changes in the composition of striated muscle proteins of rat at different stages after birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221998"} {"pmid": "4221999", "title": "Studies on hepatic glycogenolysis in protein malnutrition.", "content": "Studies on hepatic glycogenolysis in protein malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4221999"} {"pmid": "4222000", "title": "A comparative study on the release of peptides from buffalo & cow milk caseins by trypsin.", "content": "A comparative study on the release of peptides from buffalo & cow milk caseins by trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222000"} {"pmid": "4222002", "title": "Haemagglutinins of field bean (Dolichos lablab). I. Isolation, purification & properties of haemagglutinins.", "content": "Haemagglutinins of field bean (Dolichos lablab). I. Isolation, purification & properties of haemagglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222002"} {"pmid": "4222001", "title": "Studies on the proteose-peptone fraction of milk: isolation & properties of proteose-peptone & proteose from cow & buffalo milk.", "content": "Studies on the proteose-peptone fraction of milk: isolation & properties of proteose-peptone & proteose from cow & buffalo milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222001"} {"pmid": "4222003", "title": "Haemagglutinins of field bean (Dolichos lablab). II. Effect of feeding field bean haemagglutinin A on rat growth.", "content": "Haemagglutinins of field bean (Dolichos lablab). II. Effect of feeding field bean haemagglutinin A on rat growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222003"} {"pmid": "4222005", "title": "Essential amino acid requirements of the silkworm, Bombyx mori L.", "content": "Essential amino acid requirements of the silkworm, Bombyx mori L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222005"} {"pmid": "4222004", "title": "Finger print patterns of peptic and alpha-chymotryptic digests of ox liver and erythrocyte catalases.", "content": "Finger print patterns of peptic and alpha-chymotryptic digests of ox liver and erythrocyte catalases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222004"} {"pmid": "4222007", "title": "Record of the guinea worm-Dracunculus medinensis in an Alsatian bitch.", "content": "Record of the guinea worm-Dracunculus medinensis in an Alsatian bitch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222007"} {"pmid": "4222006", "title": "Lactic acid & lactic dehydrogenase activity in the blood of patients with essential hypertension.", "content": "Lactic acid & lactic dehydrogenase activity in the blood of patients with essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222006"} {"pmid": "4222009", "title": "Effect of plasmin on outflow resistance in the primate eye.", "content": "Effect of plasmin on outflow resistance in the primate eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222009"} {"pmid": "4222020", "title": "Marquio's disease.", "content": "Marquio's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222020"} {"pmid": "4222021", "title": "The evaluation of verbal performance in multiply handicapped blind children.", "content": "The evaluation of verbal performance in multiply handicapped blind children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222021"} {"pmid": "4222023", "title": "The primary histologic lesion of seborrheic dermatitis and psoriasis.", "content": "The primary histologic lesion of seborrheic dermatitis and psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222023"} {"pmid": "4222024", "title": "Occupational disease.", "content": "Occupational disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222024"} {"pmid": "4222026", "title": "Right ventricular hypertrophy at high altitude.", "content": "Right ventricular hypertrophy at high altitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222026"} {"pmid": "4222027", "title": "Incorporation of D-[I-14C]galactosamine into serum proteins and tissues of the rat.", "content": "Incorporation of D-[I-14C]galactosamine into serum proteins and tissues of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222027"} {"pmid": "4222028", "title": "Hexosamine and acid glycosaminoglycans in human teeth.", "content": "Hexosamine and acid glycosaminoglycans in human teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222028"} {"pmid": "4222029", "title": "Acid mucopolysaccharides of tadpole tail fin and back skin.", "content": "Acid mucopolysaccharides of tadpole tail fin and back skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222029"} {"pmid": "4222030", "title": "Acid mucopolysaccharide composition of human-heart valve.", "content": "Acid mucopolysaccharide composition of human-heart valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222030"} {"pmid": "4222031", "title": "Isolation of neutral sugar-containing mucopolysaccharides from cattle retina.", "content": "Isolation of neutral sugar-containing mucopolysaccharides from cattle retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222031"} {"pmid": "4222032", "title": "The effect of sulfate deficiency on the mechanical strength of the rat's aorta.", "content": "The effect of sulfate deficiency on the mechanical strength of the rat's aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222032"} {"pmid": "4222033", "title": "The isolation of a dermatan sulphate-protein complex from bovine heart valves.", "content": "The isolation of a dermatan sulphate-protein complex from bovine heart valves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222033"} {"pmid": "4222035", "title": "The activation of mitochondrial adenosine triphosphatase by calcium.", "content": "The activation of mitochondrial adenosine triphosphatase by calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222035"} {"pmid": "4222034", "title": "The interaction of collagen and acid mucopolysaccharides. A model for connective tissue.", "content": "The interaction of collagen and acid mucopolysaccharides. A model for connective tissue. 1. The interaction of acid mucopolysaccharides of connective tissue with solubilized collagen of native, or near-native, structure was investigated by free solution electrophoresis at pH7.0. 2. Complex-formation was detected by the appearance of a third peak in the ascending limb only, indicating reversible association. 3. Complex-formation was destroyed by prior heating of solubilized collagen, indicating a probable requirement for high molecular weight or internal structure of the protein. 4. Hyaluronate and chondroitin sulphate of mol.wt. 50000 gave complexes with soluble collagen at I 0.4, whereas heparin and chondroitin sulphate of mol.wt. 15000-18000 did not. All mucopolysaccharides yielded complexes at I 0.1. The stability of the complex appears mainly dependent on electrostatic forces and is increased with increase in chain length of the polysaccharide. 5. Solubilized collagen interacted to yield gels with the ;native' chondroitin sulphate-protein macro-molecule from cartilage. 6. A schematic model for the interaction of collagen and chondroitin sulphate-protein macromolecules shows parallel-ordered interaction of collagen fibrils with chondroitin sulphate side chains of the chondroitin sulphate-protein macromolecule. The biological implications of this model are discussed, particularly in relation to the ordered structures and the ionic-network properties of the intercellular components of connective tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222034"} {"pmid": "4222036", "title": "An adenosine triphosphatase from frog gastric mucosa.", "content": "An adenosine triphosphatase from frog gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222036"} {"pmid": "4222040", "title": "Histologic changes produced by endotracheal intubation.", "content": "Histologic changes produced by endotracheal intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222040"} {"pmid": "4222043", "title": "The accumulation of sodium and calcium in a specific layer of frog skin.", "content": "The accumulation of sodium and calcium in a specific layer of frog skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222043"} {"pmid": "4222044", "title": "The painful shoulder. The scapulocostal syndrome in shoulder pain.", "content": "The painful shoulder. The scapulocostal syndrome in shoulder pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222044"} {"pmid": "4222046", "title": "Structure of a polysaccharide protein complex.", "content": "Structure of a polysaccharide protein complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222046"} {"pmid": "4222050", "title": "Variations in lipid intake and their influence on respiration and tricarboxylic acid cycle activity.", "content": "Variations in lipid intake and their influence on respiration and tricarboxylic acid cycle activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222050"} {"pmid": "4222051", "title": "A study on dermatitis in rice farmers.", "content": "A study on dermatitis in rice farmers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222051"} {"pmid": "4222052", "title": "Meiosis in a male with Down's syndrome.", "content": "Meiosis in a male with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222052"} {"pmid": "4222054", "title": "A new deal for the aged and disabled.", "content": "A new deal for the aged and disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222054"} {"pmid": "4222055", "title": "Cardiomegaly after repeated application of isoprenalin in the rat.", "content": "Cardiomegaly after repeated application of isoprenalin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222055"} {"pmid": "4222056", "title": "Heart attacks and workmen's compensation acts.", "content": "Heart attacks and workmen's compensation acts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222056"} {"pmid": "4222058", "title": "Model train helps the limbless.", "content": "Model train helps the limbless.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222058"} {"pmid": "4222057", "title": "The social distance of the exceptional: a study at the high school level.", "content": "The social distance of the exceptional: a study at the high school level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222057"} {"pmid": "4222062", "title": "The role of phosphofructokinase in metabolic regulation.", "content": "The role of phosphofructokinase in metabolic regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222062"} {"pmid": "4222063", "title": "Effect of changes in hormonal and dietary status of rats and mice on the activity of their liver glutamic dehydrogenases.", "content": "Effect of changes in hormonal and dietary status of rats and mice on the activity of their liver glutamic dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222063"} {"pmid": "4222065", "title": "The abdominal neourethra.", "content": "The abdominal neourethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222065"} {"pmid": "4222069", "title": "Toxic epidermal necrolysis (the scalded skin syndrome). Its association in two cases with pathogenic staphylococci and its similarity in infancy to Ritter's disease.", "content": "Toxic epidermal necrolysis (the scalded skin syndrome). Its association in two cases with pathogenic staphylococci and its similarity in infancy to Ritter's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222069"} {"pmid": "4222071", "title": "A symmetrical simultaneous paried comparison of triamcinolone acetonide ointment and cream.", "content": "A symmetrical simultaneous paried comparison of triamcinolone acetonide ointment and cream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222071"} {"pmid": "4222072", "title": "Electromyographic validation of pain relief: a pilot study in orthopedic patients.", "content": "Electromyographic validation of pain relief: a pilot study in orthopedic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222072"} {"pmid": "4222073", "title": "Investigations on a plasminogen activator in two blood-suckers, Rhodnius prolixus Stål and Hirudo medicinalis.", "content": "Investigations on a plasminogen activator in two blood-suckers, Rhodnius prolixus Stål and Hirudo medicinalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222073"} {"pmid": "4222074", "title": "Studies on acid mucopolysaccharides of pig gastric mucin. II.", "content": "Studies on acid mucopolysaccharides of pig gastric mucin. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222074"} {"pmid": "4222075", "title": "Modification of breakage and reunion in relation to lethal damage.", "content": "Modification of breakage and reunion in relation to lethal damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222075"} {"pmid": "4222078", "title": "A family study of Huntington's chorea with unusual manifestations.", "content": "A family study of Huntington's chorea with unusual manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222078"} {"pmid": "4222079", "title": "State or Federal Workmen's Compensation--a conflict.", "content": "State or Federal Workmen's Compensation--a conflict.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222079"} {"pmid": "4222080", "title": "Progress in workmen's compensation.", "content": "Progress in workmen's compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222080"} {"pmid": "4222081", "title": "Progress in rehabilitation of the injured worker.", "content": "Progress in rehabilitation of the injured worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222081"} {"pmid": "4222082", "title": "Dehydroepiandrosterone in human seminal plasma.", "content": "Dehydroepiandrosterone in human seminal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222082"} {"pmid": "4222084", "title": "Psychiatry and the rehabilitation of the physically disabled.", "content": "Psychiatry and the rehabilitation of the physically disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222084"} {"pmid": "4222086", "title": "Diagnosis of Hurler's syndrome in the hospital laboratory and the determination of its genetic type.", "content": "Diagnosis of Hurler's syndrome in the hospital laboratory and the determination of its genetic type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222086"} {"pmid": "4222087", "title": "Indication for an allosteric effect of ADP on actomyosin gels and glycerinated fibres from insect fibrillar flight muscle.", "content": "Indication for an allosteric effect of ADP on actomyosin gels and glycerinated fibres from insect fibrillar flight muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222087"} {"pmid": "4222088", "title": "Clinical experiences in ureteroileocutaneostomy.", "content": "Clinical experiences in ureteroileocutaneostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222088"} {"pmid": "4222089", "title": "Modern cytogenetic technics. Clinical review of chromosomal analyses in a children's hospital.", "content": "Modern cytogenetic technics. Clinical review of chromosomal analyses in a children's hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222089"} {"pmid": "4222091", "title": "The direction of animal care.", "content": "The direction of animal care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222091"} {"pmid": "4222092", "title": "Spontaneous tumors in the Mongolian gerbil.", "content": "Spontaneous tumors in the Mongolian gerbil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222092"} {"pmid": "4222083", "title": "The coronary spectrum. Essentials of the legal issues in workmen's compensation.", "content": "The coronary spectrum. Essentials of the legal issues in workmen's compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222083"} {"pmid": "4222093", "title": "A comparison of the growth and fat utilization of Caesarean-derived and conventional albino rats.", "content": "A comparison of the growth and fat utilization of Caesarean-derived and conventional albino rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222093"} {"pmid": "4222094", "title": "Paraldehyde: an anesthesia for recovery experiments in albino rabbits.", "content": "Paraldehyde: an anesthesia for recovery experiments in albino rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222094"} {"pmid": "4222095", "title": "Pasteurella pneumotropica: cultural and biochemical characteristics, and its association with disease in laboratory animals.", "content": "Pasteurella pneumotropica: cultural and biochemical characteristics, and its association with disease in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222095"} {"pmid": "4222096", "title": "Normal values for hemoglobin concentration and cellular elements in the blood of Mongolian gerbils.", "content": "Normal values for hemoglobin concentration and cellular elements in the blood of Mongolian gerbils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222096"} {"pmid": "4222097", "title": "The sterilisation of laboratory animal diet by ethylene oxide.", "content": "The sterilisation of laboratory animal diet by ethylene oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222097"} {"pmid": "4222098", "title": "The care, handling and anesthesia of the snowshoe hare (Lepus americanus).", "content": "The care, handling and anesthesia of the snowshoe hare (Lepus americanus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222098"} {"pmid": "4222099", "title": "The metabolism, pulse rate and body temperature of normal, thyroidectomized and hypermetabolic rats.", "content": "The metabolism, pulse rate and body temperature of normal, thyroidectomized and hypermetabolic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222099"} {"pmid": "4222100", "title": "Semi-automatic recording and electronic processing of chronic rat toxicity data.", "content": "Semi-automatic recording and electronic processing of chronic rat toxicity data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222100"} {"pmid": "4222101", "title": "A study of the efficacy of thiabendazole and dithiazanine iodide-piperazine citrate suspension against intestinal parasites in the Macaca mulatta.", "content": "A study of the efficacy of thiabendazole and dithiazanine iodide-piperazine citrate suspension against intestinal parasites in the Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222101"} {"pmid": "4222103", "title": "Environmental factors influencing stereotyped and allelomimetic behavior in animals.", "content": "Environmental factors influencing stereotyped and allelomimetic behavior in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222103"} {"pmid": "4222102", "title": "A comparison of the hemograms of conditioned and non-conditioned laboratory dogs.", "content": "A comparison of the hemograms of conditioned and non-conditioned laboratory dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222102"} {"pmid": "4222104", "title": "A foot-operated watering device for use with special fluids.", "content": "A foot-operated watering device for use with special fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222104"} {"pmid": "4222105", "title": "The faultless mouse holder.", "content": "The faultless mouse holder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222105"} {"pmid": "4222106", "title": "A technique for prolonged infusion of rats.", "content": "A technique for prolonged infusion of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222106"} {"pmid": "4222107", "title": "The mansion on Richmond Hill.", "content": "The mansion on Richmond Hill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222107"} {"pmid": "4222108", "title": "Symposium: The handicapped child.", "content": "Symposium: The handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222108"} {"pmid": "4222109", "title": "Neuro-muscular transmission in the kitten. A preliminary note.", "content": "Neuro-muscular transmission in the kitten. A preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222109"} {"pmid": "4222110", "title": "Potassium transport and control of glycolysis in human erythrocytes.", "content": "Potassium transport and control of glycolysis in human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222110"} {"pmid": "4222111", "title": "Effects of vitamin A on mucopolysaccharides of rat blood platelets.", "content": "Effects of vitamin A on mucopolysaccharides of rat blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222111"} {"pmid": "4222112", "title": "Studies of enzyme systems utilizing automated methodology.", "content": "Studies of enzyme systems utilizing automated methodology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222112"} {"pmid": "4222113", "title": "Burn wound complication.", "content": "Burn wound complication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222113"} {"pmid": "4222115", "title": "Twins, probably monozygotic: one mongoloid with 48 chromosomes, the other normal.", "content": "Twins, probably monozygotic: one mongoloid with 48 chromosomes, the other normal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222115"} {"pmid": "4222114", "title": "The relation of the light-dependent and light-triggered adenosine triphosphatases to photophosphorylation.", "content": "The relation of the light-dependent and light-triggered adenosine triphosphatases to photophosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222114"} {"pmid": "4222117", "title": "An effective oral antifungal for chronic infections in the aged.", "content": "An effective oral antifungal for chronic infections in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222117"} {"pmid": "4222118", "title": "Onychomycosis treated with ultrafine griseofulvin.", "content": "Onychomycosis treated with ultrafine griseofulvin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222118"} {"pmid": "4222120", "title": "Care and raising of newborn baboons.", "content": "Care and raising of newborn baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222120"} {"pmid": "4222121", "title": "The need for a large standard laboratory dog.", "content": "The need for a large standard laboratory dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222121"} {"pmid": "4222122", "title": "The trematodes of laboratory primates.", "content": "The trematodes of laboratory primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222122"} {"pmid": "4222123", "title": "A method for intravenous injection and collection of blood from rats and mice without restraint and anesthesia.", "content": "A method for intravenous injection and collection of blood from rats and mice without restraint and anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222123"} {"pmid": "4222124", "title": "The hematogram of the squirrel monkey (Saimiri sciureus).", "content": "The hematogram of the squirrel monkey (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222124"} {"pmid": "4222125", "title": "The germfree cat.", "content": "The germfree cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222125"} {"pmid": "4222126", "title": "Successful prevention of infantile diarrhea of mice during an epizootic by means of a new filter cage unopened from birth to weaning.", "content": "Successful prevention of infantile diarrhea of mice during an epizootic by means of a new filter cage unopened from birth to weaning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222126"} {"pmid": "4222127", "title": "A device to restrain the mouse, rat, hamster and chinchilla to facilitate semen collection and other reproductive studies.", "content": "A device to restrain the mouse, rat, hamster and chinchilla to facilitate semen collection and other reproductive studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222127"} {"pmid": "4222128", "title": "Small laboratory animal feeding technique.", "content": "Small laboratory animal feeding technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222128"} {"pmid": "4222129", "title": "A rat resuscitator.", "content": "A rat resuscitator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222129"} {"pmid": "4222130", "title": "Infertility of guinea pigs on sawdust bedding.", "content": "Infertility of guinea pigs on sawdust bedding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222130"} {"pmid": "4222148", "title": "Enzyme-histochemical studies on the healing process of split skin grafts. II. 5-Nucleotidase, adenosinetriphosphatase, acid and alkaline phosphatase in autografts.", "content": "Enzyme-histochemical studies on the healing process of split skin grafts. II. 5-Nucleotidase, adenosinetriphosphatase, acid and alkaline phosphatase in autografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222148"} {"pmid": "4222153", "title": "Nicotinamide content of insects.", "content": "Nicotinamide content of insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222153"} {"pmid": "4222154", "title": "Studies with the ATPase of adrenal medulla.", "content": "Studies with the ATPase of adrenal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222154"} {"pmid": "4222155", "title": "Lysogenic conversion of staphylococci to loss of beta-toxin.", "content": "Lysogenic conversion of staphylococci to loss of beta-toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222155"} {"pmid": "4222156", "title": "The autolysis of Clostridium sporogenes.", "content": "The autolysis of Clostridium sporogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222156"} {"pmid": "4222157", "title": "Heart size after isolated replacement of mitral or aortic valve.", "content": "Heart size after isolated replacement of mitral or aortic valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222157"} {"pmid": "4222167", "title": "Arthus-like reaction of skin allograft (homograft) induced by serum antibodies.", "content": "Arthus-like reaction of skin allograft (homograft) induced by serum antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222167"} {"pmid": "4222171", "title": "Panel on medicolegal considerations in workmen's compensation.", "content": "Panel on medicolegal considerations in workmen's compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222171"} {"pmid": "4222165", "title": "Eradication of bovine brucellosis in Moscow region.", "content": "Eradication of bovine brucellosis in Moscow region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222165"} {"pmid": "4222175", "title": "The influence of rotation of the trunk on the anatomy of the inguinal canal.", "content": "The influence of rotation of the trunk on the anatomy of the inguinal canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222175"} {"pmid": "4222174", "title": "Disorders of the hair and their treatment before the 18th century.", "content": "Disorders of the hair and their treatment before the 18th century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222174"} {"pmid": "4222176", "title": "The pesticide problem--return to sanity.", "content": "The pesticide problem--return to sanity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222176"} {"pmid": "4222177", "title": "Technical errors in peritoneoscopy.", "content": "Technical errors in peritoneoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222177"} {"pmid": "4222178", "title": "Enzyme nomenclature. Recommendations of the International Union of Biochemistry.", "content": "Enzyme nomenclature. Recommendations of the International Union of Biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222178"} {"pmid": "4222166", "title": "Some questions of diagnosis of brucellosis and specific preventive measures in the Kazakh Soviet Republic.", "content": "Some questions of diagnosis of brucellosis and specific preventive measures in the Kazakh Soviet Republic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222166"} {"pmid": "4222179", "title": "Nicotinamide deamidase from rabbit liver.", "content": "Nicotinamide deamidase from rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222179"} {"pmid": "4222181", "title": "Extracellular space in the central nervous system.", "content": "Extracellular space in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222181"} {"pmid": "4222182", "title": "The influence of parathyroid extract on phalanges of the embryonic fowl in vitro.", "content": "The influence of parathyroid extract on phalanges of the embryonic fowl in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222182"} {"pmid": "4222183", "title": "The occurrence of some carbohydrates and collagen in Obeliscoides cuniculi (Graybill, 1923), a nematode parasite of the rabbit.", "content": "The occurrence of some carbohydrates and collagen in Obeliscoides cuniculi (Graybill, 1923), a nematode parasite of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222183"} {"pmid": "4222184", "title": "Congenital defects involving the abdominal wall, sternum, diaphragm and pericardium: case report and review of embryologic factors.", "content": "Congenital defects involving the abdominal wall, sternum, diaphragm and pericardium: case report and review of embryologic factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222184"} {"pmid": "4222191", "title": "Early loss of teeth in children.", "content": "Early loss of teeth in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222191"} {"pmid": "4222192", "title": "Acrodynia or pink disease.", "content": "Acrodynia or pink disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222192"} {"pmid": "4222193", "title": "Massive melena.", "content": "Massive melena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222193"} {"pmid": "4222194", "title": "Diagnosis and treatment of parathion poisoning.", "content": "Diagnosis and treatment of parathion poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222194"} {"pmid": "4222195", "title": "Molecular events resulting in radiation injury, repair and sensitization of DNA.", "content": "Molecular events resulting in radiation injury, repair and sensitization of DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222195"} {"pmid": "4222196", "title": "Annual report: Arkansas State Board of Health.", "content": "Annual report: Arkansas State Board of Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222196"} {"pmid": "4222197", "title": "Appendicitis in pregnancy.", "content": "Appendicitis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222197"} {"pmid": "4222198", "title": "The compromised fetus.", "content": "The compromised fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222198"} {"pmid": "4222199", "title": "Arkansas morbidity--1965.", "content": "Arkansas morbidity--1965.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222199"} {"pmid": "4222200", "title": "The nursing situation.", "content": "The nursing situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222200"} {"pmid": "4222201", "title": "Application of psychological principles to dental practice.", "content": "Application of psychological principles to dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222201"} {"pmid": "4222202", "title": "Premedication for children.", "content": "Premedication for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222202"} {"pmid": "4222203", "title": "The impact of water fluoridation on the practice of dentistry for children.", "content": "The impact of water fluoridation on the practice of dentistry for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222203"} {"pmid": "4222204", "title": "The effect of appointment length on behavior of the pedodontic patient and his attitude toward dentistry.", "content": "The effect of appointment length on behavior of the pedodontic patient and his attitude toward dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222204"} {"pmid": "4222206", "title": "The psychological preparation of the child for dental surgery. II.", "content": "The psychological preparation of the child for dental surgery. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222206"} {"pmid": "4222207", "title": "Activity projects.", "content": "Activity projects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222207"} {"pmid": "4222208", "title": "Preparatory training bureau.", "content": "Preparatory training bureau.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222208"} {"pmid": "4222209", "title": "Banstead Place.", "content": "Banstead Place.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222209"} {"pmid": "4222211", "title": "Measurement of anxiety in children during routine dental procedures.", "content": "Measurement of anxiety in children during routine dental procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222211"} {"pmid": "4222212", "title": "What do Georgia dentists think about dentistry for mentally retarded children?", "content": "What do Georgia dentists think about dentistry for mentally retarded children?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222212"} {"pmid": "4222213", "title": "Dental care for children.", "content": "Dental care for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222213"} {"pmid": "4222214", "title": "Dental problems and programs for the chronically ill and aging.", "content": "Dental problems and programs for the chronically ill and aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222214"} {"pmid": "4222215", "title": "The effectiveness of the electric toothbrush in reducing oral debris in handicapped children.", "content": "The effectiveness of the electric toothbrush in reducing oral debris in handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222215"} {"pmid": "4222217", "title": "Independence in a wheelchair; useful booklet for the disabled.", "content": "Independence in a wheelchair; useful booklet for the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222217"} {"pmid": "4222218", "title": "Industrial dermatitis.", "content": "Industrial dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222218"} {"pmid": "4222216", "title": "Dentistry's new horizon--dentistry for the handicapped.", "content": "Dentistry's new horizon--dentistry for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222216"} {"pmid": "4222219", "title": "Industrial dermatitis.", "content": "Industrial dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222219"} {"pmid": "4222220", "title": "The long struggle against crippling disease.", "content": "The long struggle against crippling disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222220"} {"pmid": "4222223", "title": "Dental care for retarded children.", "content": "Dental care for retarded children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222223"} {"pmid": "4222224", "title": "John Groom's crippleage.", "content": "John Groom's crippleage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222224"} {"pmid": "4222226", "title": "The composition of the cell wall of Lactobacillius bifidus var. pennsylvanicus.", "content": "The composition of the cell wall of Lactobacillius bifidus var. pennsylvanicus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222226"} {"pmid": "4222228", "title": "The effect of quinidine on the activity of a sodium-potassium activated, magnesium-dependent ATPase enzyme isolated from toad cardiac muscle.", "content": "The effect of quinidine on the activity of a sodium-potassium activated, magnesium-dependent ATPase enzyme isolated from toad cardiac muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222228"} {"pmid": "4222229", "title": "A cation activated adenosinetriphosphatase in cell membranes of halophilic Vibrio parahaemolyticus.", "content": "A cation activated adenosinetriphosphatase in cell membranes of halophilic Vibrio parahaemolyticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222229"} {"pmid": "4222230", "title": "The effect of carnosine on myofibrillar ATPase activity.", "content": "The effect of carnosine on myofibrillar ATPase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222230"} {"pmid": "4222231", "title": "Depression of facilitatory influences on spinal motor activity by carisoprodol.", "content": "Depression of facilitatory influences on spinal motor activity by carisoprodol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222231"} {"pmid": "4222232", "title": "Staphylococci in man and animals. Distribution and characteristics of strains.", "content": "Staphylococci in man and animals. Distribution and characteristics of strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222232"} {"pmid": "4222235", "title": "Diagnostic considerations in management of penetrating abdominal wounds.", "content": "Diagnostic considerations in management of penetrating abdominal wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222235"} {"pmid": "4222234", "title": "Experiences with peritoneoscopy at Walter Reed General Hospital, 1964-1965.", "content": "Experiences with peritoneoscopy at Walter Reed General Hospital, 1964-1965.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222234"} {"pmid": "4222236", "title": "The management of gunshot wounds of the extremities.", "content": "The management of gunshot wounds of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222236"} {"pmid": "4222237", "title": "Neurologic phenomena of leukemia.", "content": "Neurologic phenomena of leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222237"} {"pmid": "4222238", "title": "Urinary output of total and individual fractions of 17-ketosteroids in patients with acne.", "content": "Urinary output of total and individual fractions of 17-ketosteroids in patients with acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222238"} {"pmid": "4222239", "title": "Massive left atriomegaly.", "content": "Massive left atriomegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222239"} {"pmid": "4222240", "title": "Thyrocardiac disease--fact or fancy?", "content": "Thyrocardiac disease--fact or fancy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222240"} {"pmid": "4222241", "title": "Contact dermatitis caused by the 'manzanillo' (Rhus striata) tree. Report of three cases.", "content": "Contact dermatitis caused by the 'manzanillo' (Rhus striata) tree. Report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222241"} {"pmid": "4222242", "title": "Rupture of the inferior epigastric artery with rectus-sheath hematoma.", "content": "Rupture of the inferior epigastric artery with rectus-sheath hematoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222242"} {"pmid": "4222243", "title": "Limitations of the electrocardiographic diagnosis of ventricular hypertrophy.", "content": "Limitations of the electrocardiographic diagnosis of ventricular hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222243"} {"pmid": "4222246", "title": "The failure of some aromatic amines to produce hemiglobin in vivo in spite of microsomal N-hydroxylation.", "content": "The failure of some aromatic amines to produce hemiglobin in vivo in spite of microsomal N-hydroxylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222246"} {"pmid": "4222247", "title": "The low activity of aniline in producing hemiglobin in rabbits.", "content": "The low activity of aniline in producing hemiglobin in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222247"} {"pmid": "4222248", "title": "The formation of hemiglobin by p-hydroxylaminobenzenesulfonamide in vivo and in vitro.", "content": "The formation of hemiglobin by p-hydroxylaminobenzenesulfonamide in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222248"} {"pmid": "4222253", "title": "How a pharmaceutical manufacturer tests products for sterility.", "content": "How a pharmaceutical manufacturer tests products for sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222253"} {"pmid": "4222254", "title": "Clean room garment selection and care.", "content": "Clean room garment selection and care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222254"} {"pmid": "4222256", "title": "Emerging problems in oral health care and clinical research in a chronic disease hospital.", "content": "Emerging problems in oral health care and clinical research in a chronic disease hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222256"} {"pmid": "4222257", "title": "Regulation of metabolism in working muscle in vivo. II. Concentrations of adenine nucleotides, arginine phosphate, and inorganic phosphate in insect flight muscle during flight.", "content": "Regulation of metabolism in working muscle in vivo. II. Concentrations of adenine nucleotides, arginine phosphate, and inorganic phosphate in insect flight muscle during flight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222257"} {"pmid": "4222258", "title": "Studies on thymidine kinase of human liver cells in culture.", "content": "Studies on thymidine kinase of human liver cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222258"} {"pmid": "4222261", "title": "Special schools over a century.", "content": "Special schools over a century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222261"} {"pmid": "4222262", "title": "Wheel-chairs on the campus?", "content": "Wheel-chairs on the campus?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222262"} {"pmid": "4222268", "title": "Cerebral biopsy in the investigation of presenile dementia. I. Clinical aspects.", "content": "Cerebral biopsy in the investigation of presenile dementia. I. Clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222268"} {"pmid": "4222270", "title": "Salutary effects of prochlorperazine on chronic psychotic choreo-athetosis.", "content": "Salutary effects of prochlorperazine on chronic psychotic choreo-athetosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222270"} {"pmid": "4222275", "title": "Role of phospholipid in the activation of Na+, Ka+-activated adenosine triphosphatase of beef brain.", "content": "Role of phospholipid in the activation of Na+, Ka+-activated adenosine triphosphatase of beef brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222275"} {"pmid": "4222277", "title": "Cellular response of seborrheic keratosis following croton oil irritation and surgical trauma with special reference to melanoacanthoma.", "content": "Cellular response of seborrheic keratosis following croton oil irritation and surgical trauma with special reference to melanoacanthoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222277"} {"pmid": "4222281", "title": "Visual discrimination learning in imbecile children with nonreinforcement of irrelevant tendencies.", "content": "Visual discrimination learning in imbecile children with nonreinforcement of irrelevant tendencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222281"} {"pmid": "4222282", "title": "The nucleoli in mitotic divisions of mammalian cells in vitro.", "content": "The nucleoli in mitotic divisions of mammalian cells in vitro. In a number of mammalian cell strains nucleoli persisted through mitosis. This phenomenon was especially pronounced in several cell lines derived from Chinese hamster tissues. All the methods employed, including radioautography with tritiated uridine, cytochemical stains (methyl green-pyronin and azure B), fluorescent microscopy (coriphosphine O), ribonuclease digestion, and electron microscopy, demonstrated that the bodies identified as persistent nucleoli in the mitotic stages had the same characteristics as did the nucleoli in the interphase. Persistent nucleoli may attach to the chromosomes or may be free in the cytoplasm. In cells where no persistent nucleoli as such were noted, nucleolar material was observed to attach to the chromosomes in shapeless masses which moved with the chromosomes during anaphase. At least a portion of the nucleolar material was included in the daughter nuclei, presumably for immediate use for protein synthesis after cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222282"} {"pmid": "4222284", "title": "Poison ivy in Melbourne.", "content": "Poison ivy in Melbourne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222284"} {"pmid": "4222283", "title": "Density gradient separation of sarcotubular vesicles and other particulate constituents of rabbit muscle.", "content": "Density gradient separation of sarcotubular vesicles and other particulate constituents of rabbit muscle. Separation of particulate matter in rabbit muscle extracts by differential centrifugation leads, in first approximation, to the isolation of fraction I (15,000 to 41,000 g) and fraction II (41,000 to 150,000 g). The former consists mainly of sarcotubular material, actively transporting calcium ions, and displaying relaxation factor activity. The latter is heterogeneous, shows little calcium accumulation, and contains factors both inhibiting and activating myofibrillar ATPase. Fraction I is resolved by density gradient centrifugation into 2 main subfractions. The lighter one represents sarcotubular material in the best state of preservation, with biochemical activities stable for weeks in the cold. The heavier one may consist of the same material in a less well preserved form. Upon aging, it develops an activating activity toward myofibrillar ATPase, when the relaxing effect has declined. Fraction II is resolved by density gradient centrifugation into 3 or more fractions, with some variability. Relaxing activity in terms of inhibition of myofibrillar ATPase predominates among the lighter subfractions, increase of ATPase among the heavier. The intrinsic ATPase of fraction II is activated by calcium ions, but there is little or no bulk accumulation of calcium oxalate. Nevertheless, its limited calcium uptake seems to suffice to explain its relaxing activity. The particulate material contains mucopolysaccharide and lipid. Most of the lipid in fraction I is phospholipid; in fraction II this is less than half, if calculated as lecithin. The unfractionated material contains an adenylcyclase. There is no acetylcholine esterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222283"} {"pmid": "4222278", "title": "Comparative studies on serum lipids and histochemical features of the arterial wall in animal species differently susceptible to experimental atherosclerosis.", "content": "Comparative studies on serum lipids and histochemical features of the arterial wall in animal species differently susceptible to experimental atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222278"} {"pmid": "4222315", "title": "Camping for crippled children.", "content": "Camping for crippled children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222315"} {"pmid": "4222316", "title": "The effect of hydrocortisone on chondroitin sulfate production and loss by embryonic chick tibiotarsi in organ culture.", "content": "The effect of hydrocortisone on chondroitin sulfate production and loss by embryonic chick tibiotarsi in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222316"} {"pmid": "4222317", "title": "Separation of acid polysaccharides by starch gel electrophoresis.", "content": "Separation of acid polysaccharides by starch gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222317"} {"pmid": "4222318", "title": "The complex nature of phosphofructokinase - a nucleic acid containing enzyme.", "content": "The complex nature of phosphofructokinase - a nucleic acid containing enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222318"} {"pmid": "4222319", "title": "On the functional significance of the nucleic acid - protein complex of phosphofructokinase.", "content": "On the functional significance of the nucleic acid - protein complex of phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222319"} {"pmid": "4222321", "title": "Physical education in a rehabilitation center.", "content": "Physical education in a rehabilitation center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222321"} {"pmid": "4222320", "title": "Distribution of mucopolysaccharides in the human vascular tree.", "content": "Distribution of mucopolysaccharides in the human vascular tree.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222320"} {"pmid": "4222323", "title": "Sulfur mustard: reaction with L-cells treated with 5-fluorodeoxyuridine.", "content": "Sulfur mustard: reaction with L-cells treated with 5-fluorodeoxyuridine. After exposure to 5-fluorodeoxyuridine, L-cells are considerably more sensitive to the lethal effect of sulfur mustard than after they have been released from this block by addition of thymidine and allowed to proceed into the G2 phase of the division cycle. Nevertheless, for both populations, the amounts of mustard bound per cell and per nucleus (expressed as the amount of mustard per unit of protein) were the same. Likewise, the amounts of mustard bound per unit of DNA were the same for both populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222323"} {"pmid": "4222325", "title": "Further studies on the myofibrillar adenosine triphosphatase-inhibitory activity and the Mg++-dependent adenosine triphosphatase of the relaxing granules.", "content": "Further studies on the myofibrillar adenosine triphosphatase-inhibitory activity and the Mg++-dependent adenosine triphosphatase of the relaxing granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222325"} {"pmid": "4222326", "title": "Effect of sample site on fatty acid composition of adipose tissue.", "content": "Effect of sample site on fatty acid composition of adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222326"} {"pmid": "4222328", "title": "Discharges of semitendinosus fusimotor neurones in the decerebrated and spinalized rabbit.", "content": "Discharges of semitendinosus fusimotor neurones in the decerebrated and spinalized rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222328"} {"pmid": "4222327", "title": "Uptake of fibrinogen and fibrinolytic enzymes by neoplastic tissue.", "content": "Uptake of fibrinogen and fibrinolytic enzymes by neoplastic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222327"} {"pmid": "4222329", "title": "Cardiac hypertrophy after muscular stress. Myocardial lipids modifications in rat.", "content": "Cardiac hypertrophy after muscular stress. Myocardial lipids modifications in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222329"} {"pmid": "4222330", "title": "The role of cardiac enlargement in the production of musical pericardial sounds.", "content": "The role of cardiac enlargement in the production of musical pericardial sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222330"} {"pmid": "4222332", "title": "Oxidative phosphorylation in Nitrobacter winogradskyi.", "content": "Oxidative phosphorylation in Nitrobacter winogradskyi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222332"} {"pmid": "4222333", "title": "The effect of sulphydryl-blocking reagents and of urea on the (Na+ + K+)-activated enzyme system.", "content": "The effect of sulphydryl-blocking reagents and of urea on the (Na+ + K+)-activated enzyme system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222333"} {"pmid": "4222359", "title": "The reticulocyte count in mongols.", "content": "The reticulocyte count in mongols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222359"} {"pmid": "4222360", "title": "Ovalocytosis in normal and mentally retarded subjects.", "content": "Ovalocytosis in normal and mentally retarded subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222360"} {"pmid": "4222367", "title": "The absorption spectra of protoheme and heme a complexes with amino acids and related compounds.", "content": "The absorption spectra of protoheme and heme a complexes with amino acids and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222367"} {"pmid": "4222368", "title": "The effect of tripropyltin chloride on myosin A adenosine triphosphatase.", "content": "The effect of tripropyltin chloride on myosin A adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222368"} {"pmid": "4222370", "title": "Enzyme histochemistry of skeletal muscle.", "content": "Enzyme histochemistry of skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222370"} {"pmid": "4222371", "title": "Acne vulgaris and systemic antibiotics.", "content": "Acne vulgaris and systemic antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222371"} {"pmid": "4222372", "title": "Antibiotics and the placebo reaction in acne.", "content": "Antibiotics and the placebo reaction in acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222372"} {"pmid": "4222373", "title": "Objective evaluation of demethylchlortetracycline hydrochloride in the treatment of acne.", "content": "Objective evaluation of demethylchlortetracycline hydrochloride in the treatment of acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222373"} {"pmid": "4222374", "title": "Bacteriophage therapy in infective childhood asthma.", "content": "Bacteriophage therapy in infective childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222374"} {"pmid": "4222375", "title": "Analysis of the check reflex.", "content": "Analysis of the check reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222375"} {"pmid": "4222376", "title": "Reproduction in down's syndrome (mongolism): chromosomal study of mother and normal child.", "content": "Reproduction in down's syndrome (mongolism): chromosomal study of mother and normal child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222376"} {"pmid": "4222377", "title": "Actin-myosin interaction: inhibition of the myosin adenosine triphosphatase by actin.", "content": "Actin-myosin interaction: inhibition of the myosin adenosine triphosphatase by actin. In the absence of magnesium ion, the addition of actin to myosin in a 1 :4 ratio has a strong inhibitory effect on the adenosine triphosphatase activity, in contrast to the well-known activating effect of actin in the presence of magnesium ion. This finding suggests that both effects result from a conformational change in the active site of the myosin adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222377"} {"pmid": "4222369", "title": "Localization of mitochondrial adenosine triphosphatase activity in cultured human cells.", "content": "Localization of mitochondrial adenosine triphosphatase activity in cultured human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222369"} {"pmid": "4222383", "title": "Diurnal variation in some Krebs cycle enzymes in cactus (Nopalea dejecta) phylloclades.", "content": "Diurnal variation in some Krebs cycle enzymes in cactus (Nopalea dejecta) phylloclades.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222383"} {"pmid": "4222384", "title": "Studies on enzymic synthesis of cerebroside sulphate from 3'-phosphoadenosine-5'-phosphosulphate.", "content": "Studies on enzymic synthesis of cerebroside sulphate from 3'-phosphoadenosine-5'-phosphosulphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222384"} {"pmid": "4222385", "title": "Oxidative enzymes in Escherichia coli plasma membrane.", "content": "Oxidative enzymes in Escherichia coli plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222385"} {"pmid": "4222386", "title": "Exocellular deoxyribonuclease I of Penicillium chrysogenum: I--Partial purification & properties of the enzyme.", "content": "Exocellular deoxyribonuclease I of Penicillium chrysogenum: I--Partial purification & properties of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222386"} {"pmid": "4222387", "title": "Intracellular localization & characteristics of lactate dehydrogenase activity of Salmonella typhosa (NCTC 8385).", "content": "Intracellular localization & characteristics of lactate dehydrogenase activity of Salmonella typhosa (NCTC 8385).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222387"} {"pmid": "4222388", "title": "Tricarboxylic acid cycle activity in a pseudomonad.", "content": "Tricarboxylic acid cycle activity in a pseudomonad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222388"} {"pmid": "4222389", "title": "The biochemistry of Vibrio cholerae: IV--Acid soluble nucleotide constituents.", "content": "The biochemistry of Vibrio cholerae: IV--Acid soluble nucleotide constituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222389"} {"pmid": "4222390", "title": "Effect of ultraviolet radiation on the oxidation of certain Krebs cycle substrates in Vibrio cholerae.", "content": "Effect of ultraviolet radiation on the oxidation of certain Krebs cycle substrates in Vibrio cholerae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222390"} {"pmid": "4222391", "title": "Hormonal effect on certain glycolytic enzymes of rat mammary gland.", "content": "Hormonal effect on certain glycolytic enzymes of rat mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222391"} {"pmid": "4222392", "title": "Utilization of some amino acids by human malignant cervix uteri.", "content": "Utilization of some amino acids by human malignant cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222392"} {"pmid": "4222393", "title": "Tricarboxylic acid cycle activity in human malignant cervix uteri.", "content": "Tricarboxylic acid cycle activity in human malignant cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222393"} {"pmid": "4222394", "title": "Immunochemical characterization of sheep plasma glycoprotein.", "content": "Immunochemical characterization of sheep plasma glycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222394"} {"pmid": "4222395", "title": "Release of sialic acid from caseins of cow & buffalo milk by cow & buffalo rennets.", "content": "Release of sialic acid from caseins of cow & buffalo milk by cow & buffalo rennets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222395"} {"pmid": "4222396", "title": "Biochemical alterations in rat tissue in iron deficiency anaemia & repletion with iron.", "content": "Biochemical alterations in rat tissue in iron deficiency anaemia & repletion with iron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222396"} {"pmid": "4222397", "title": "Interrelationship of dietary protein & vitamins on metabolism: I--Interdependence of the levels of certain B vitamins & dietary protein.", "content": "Interrelationship of dietary protein & vitamins on metabolism: I--Interdependence of the levels of certain B vitamins & dietary protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222397"} {"pmid": "4222398", "title": "Mode of action of psoralen in pigment production: 3--Photo-oxidation of dihydroxyphenylalanine in the presence of psoralen.", "content": "Mode of action of psoralen in pigment production: 3--Photo-oxidation of dihydroxyphenylalanine in the presence of psoralen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222398"} {"pmid": "4222399", "title": "Fatty acid composition of phosphatidyl ethanolamine of Mycobacterium tuberculosis.", "content": "Fatty acid composition of phosphatidyl ethanolamine of Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222399"} {"pmid": "4222400", "title": "Polyguanylic acid & its effect on amino acid incorporation.", "content": "Polyguanylic acid & its effect on amino acid incorporation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222400"} {"pmid": "4222401", "title": "Proteins in human milk.", "content": "Proteins in human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222401"} {"pmid": "4222402", "title": "Electrophoretic studies on cytoplasmic proteins from human malignant cervix uteri.", "content": "Electrophoretic studies on cytoplasmic proteins from human malignant cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222402"} {"pmid": "4222403", "title": "Chromosome structure in phage T4, II. Terminal redundancy and heterozygosis.", "content": "Chromosome structure in phage T4, II. Terminal redundancy and heterozygosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222403"} {"pmid": "4222404", "title": "Additional evidence for two kinds of heterozygotes in phage T4.", "content": "Additional evidence for two kinds of heterozygotes in phage T4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222404"} {"pmid": "4222405", "title": "The genetic structure of complementation heterozygotes.", "content": "The genetic structure of complementation heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222405"} {"pmid": "4222406", "title": "Synaptic activity in motoneurons during natural stimulation of muscle spindles.", "content": "Synaptic activity in motoneurons during natural stimulation of muscle spindles. Synaptic activity evoked in cat motoneurons during stretch stimulation of muscle spindles in the homonymous muscle has been studied by intracellular recording. A class of miniature excitatory postsynaptic potentials evoked by such physiologic stimulation results from activity in single group la spindle afferent fibers, and the criterion for identification is a predictable pattern of rhythmic occurrence of the synaptic potentials. Statistical examination of the amplitude distributions of this class of miniature synaptic potentials suggests that some group Ia fibers liberate a relatively large number of quantal excitatory postsynaptic potential units per fiber impulse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222406"} {"pmid": "4222407", "title": "Mucopolysaccharides: N-acetylglucosamine- and galactose-6-sulfates from keratosulfate.", "content": "Mucopolysaccharides: N-acetylglucosamine- and galactose-6-sulfates from keratosulfate. Galactose-6-sulfate and N-acetylglucosamine-6-sulfate were obtained pure from a partial acid hydrolyzate of corneal keratosulfate by paper chromatography and electrophoretic fractionation. These sugars were also present in hydrolyzates of skeletal keratosulfate. The distribution of the sulfate groups in the various keratosulfates might depend upon their source, and this distribution probably has important biological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222407"} {"pmid": "4222408", "title": "A controlled trial of rehabilitation.", "content": "A controlled trial of rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222408"} {"pmid": "4222409", "title": "Door handles for the disabled. An assessment of their suitability.", "content": "Door handles for the disabled. An assessment of their suitability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222409"} {"pmid": "4222410", "title": "Keratoelastoidosis marginalis of the hands. Synonyms: marginal keratoderma of palms; degenerative collagenous plaques of the hands.", "content": "Keratoelastoidosis marginalis of the hands. Synonyms: marginal keratoderma of palms; degenerative collagenous plaques of the hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222410"} {"pmid": "4222412", "title": "A new antibiotic against gonorrhea.", "content": "A new antibiotic against gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222412"} {"pmid": "4222413", "title": "Cytogenetic survey of 225 patients diagnosed clinically as mongols.", "content": "Cytogenetic survey of 225 patients diagnosed clinically as mongols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222413"} {"pmid": "4222418", "title": "A survey of attitudes toward the training and employing of physically handicapped speech pathologists and audiologists.", "content": "A survey of attitudes toward the training and employing of physically handicapped speech pathologists and audiologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222418"} {"pmid": "4222419", "title": "Water extrusion in isolated subcellular fractions. V. Adenosinetriphosphate hydrolysis by mitochondria during the reaction.", "content": "Water extrusion in isolated subcellular fractions. V. Adenosinetriphosphate hydrolysis by mitochondria during the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222419"} {"pmid": "4222420", "title": "The mucopolysaccharides of avian oviduct, egg, skin, and comb, and of porcine skin.", "content": "The mucopolysaccharides of avian oviduct, egg, skin, and comb, and of porcine skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222420"} {"pmid": "4222421", "title": "Griseofulvin and lupus erythematosus.", "content": "Griseofulvin and lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222421"} {"pmid": "4222422", "title": "Action and indications for solid carbon dioxide therapy in dermatology.", "content": "Action and indications for solid carbon dioxide therapy in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222422"} {"pmid": "4222423", "title": "Vectorcardiographic criteria of left and right ventricular hypertrophy with the Frank system.", "content": "Vectorcardiographic criteria of left and right ventricular hypertrophy with the Frank system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222423"} {"pmid": "4222424", "title": "Some histochemical observations on tissue of renal hypertensive animals.", "content": "Some histochemical observations on tissue of renal hypertensive animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222424"} {"pmid": "4222425", "title": "Further experiences with guanethidine--a clinical assessment of 103 patients.", "content": "Further experiences with guanethidine--a clinical assessment of 103 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222425"} {"pmid": "4222426", "title": "Trisomy D1 (13-15) in a Bantu child.", "content": "Trisomy D1 (13-15) in a Bantu child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222426"} {"pmid": "4222428", "title": "Neurons of intramural ganglia of the heart in its hyperfunction and hypertrophy.", "content": "Neurons of intramural ganglia of the heart in its hyperfunction and hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222428"} {"pmid": "4222429", "title": "Relationship between structure, specificity and genes within the ABO and Lewis blood-group systems.", "content": "Relationship between structure, specificity and genes within the ABO and Lewis blood-group systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222429"} {"pmid": "4222433", "title": "The role of Mg2+ in the contraction and adenosine triphosphatase activity of myofibrils.", "content": "The role of Mg2+ in the contraction and adenosine triphosphatase activity of myofibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222433"} {"pmid": "4222434", "title": "Metabolism in vivo of steroids in the canine ovary.", "content": "Metabolism in vivo of steroids in the canine ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222434"} {"pmid": "4222435", "title": "Carbonic anhydrase distribution in rabbit lens.", "content": "Carbonic anhydrase distribution in rabbit lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222435"} {"pmid": "4222437", "title": "The chemical specificity of the mucopolysaccharides of the cornea.", "content": "The chemical specificity of the mucopolysaccharides of the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222437"} {"pmid": "4222436", "title": "Some glycolytic enzymes and intermediates in the rabbit lens.", "content": "Some glycolytic enzymes and intermediates in the rabbit lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222436"} {"pmid": "4222439", "title": "Motor myoneural junctions on frog intrafusal muscle fibers.", "content": "Motor myoneural junctions on frog intrafusal muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222439"} {"pmid": "4222438", "title": "In vitro studies of factors affecting penetration of duck erythrocytes by avian malaria (Plasmodium lophurae).", "content": "In vitro studies of factors affecting penetration of duck erythrocytes by avian malaria (Plasmodium lophurae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222438"} {"pmid": "4222440", "title": "Demyelination regions of nerve fibers in frog muscle spindle as studied by serial sections for electron microscopy.", "content": "Demyelination regions of nerve fibers in frog muscle spindle as studied by serial sections for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222440"} {"pmid": "4222430", "title": "Congenital and acquired anatomic variations, including degenerative changes of the lower lumbar spine; role in production of painful back and lower extremity syndromes.", "content": "Congenital and acquired anatomic variations, including degenerative changes of the lower lumbar spine; role in production of painful back and lower extremity syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222430"} {"pmid": "4222442", "title": "Acid mucopolysaccharides in the Rask-Nielsen transplantable mouse mastocytoma.", "content": "Acid mucopolysaccharides in the Rask-Nielsen transplantable mouse mastocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222442"} {"pmid": "4222443", "title": "3',5'-diesters of 5-fluoro-2'-deoxyuridine: synthesis and biological activity.", "content": "3',5'-diesters of 5-fluoro-2'-deoxyuridine: synthesis and biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222443"} {"pmid": "4222445", "title": "Backache due to osteoporosis in an industrial population. A survey of 481 patients.", "content": "Backache due to osteoporosis in an industrial population. A survey of 481 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222445"} {"pmid": "4222431", "title": "Children's orthopaedic surgery in the United States: historical trends.", "content": "Children's orthopaedic surgery in the United States: historical trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222431"} {"pmid": "4222448", "title": "Pedodontics--preventive and personal.", "content": "Pedodontics--preventive and personal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222448"} {"pmid": "4222449", "title": "Spondylopathy. A clinical study of backache in the aged.", "content": "Spondylopathy. A clinical study of backache in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222449"} {"pmid": "4222450", "title": "The 99th Annual Session dedicated to Siskin brothers.", "content": "The 99th Annual Session dedicated to Siskin brothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222450"} {"pmid": "4222452", "title": "Repression of Staphylococcus aureus in associative culture.", "content": "Repression of Staphylococcus aureus in associative culture. The growth of Staphylococcus aureus MF 31 was suppressed when grown in association with Streptococcus diacetilactis and other lactic streptococci. The data indicated that the initial proportion of staphylococci present in the medium was of less importance than the depletion of vital nutrients. Investigation revealed that factors present in Yeast Nitrogen Base medium could reverse the inhibition which was due to antagonism. The major factor found was nicotinamide, and further study revealed that the biological availability of this compound was influenced by the pH of the medium. The addition of nicotinamide to depleted media with careful control of the pH resulted in increased growth of S. aureus in the test system. Further data indicated that additional factors may affect the degree of growth by S. aureus in depleted media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222452"} {"pmid": "4222453", "title": "Bacteriophage inhibition in staphylococci.", "content": "Bacteriophage inhibition in staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222453"} {"pmid": "4222455", "title": "Cardiovascular actions of the hypotensive agent, N, N-Diallylmelamine (U-7720).", "content": "Cardiovascular actions of the hypotensive agent, N, N-Diallylmelamine (U-7720).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222455"} {"pmid": "4222458", "title": "The preparation of microsomes.", "content": "The preparation of microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222458"} {"pmid": "4222461", "title": "A note on \"cancer-susceptible\" and \"cancer-resistant\" genotypes: implications for cancer detection and research.", "content": "A note on \"cancer-susceptible\" and \"cancer-resistant\" genotypes: implications for cancer detection and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222461"} {"pmid": "4222459", "title": "Species differences in the hydroxylation of aniline and N-ethylaniline by liver microsomes.", "content": "Species differences in the hydroxylation of aniline and N-ethylaniline by liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222459"} {"pmid": "4222462", "title": "An epidemiological approach to infant mortality in Omaha and Douglas County 1960-1964.", "content": "An epidemiological approach to infant mortality in Omaha and Douglas County 1960-1964.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222462"} {"pmid": "4222463", "title": "Beverage electrolytes at the Bishop Clarkson Memorial Hospital, Omaha, Nebraska.", "content": "Beverage electrolytes at the Bishop Clarkson Memorial Hospital, Omaha, Nebraska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222463"} {"pmid": "4222464", "title": "Congenital strictures of the esophagus.", "content": "Congenital strictures of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222464"} {"pmid": "4222465", "title": "Fluid balance--intake and output charts, a revised form.", "content": "Fluid balance--intake and output charts, a revised form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222465"} {"pmid": "4222466", "title": "The Penrose industrial health centre.", "content": "The Penrose industrial health centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222466"} {"pmid": "4222467", "title": "Effect of glucocorticoids upon the mucopolysaccharide content of human skin.", "content": "Effect of glucocorticoids upon the mucopolysaccharide content of human skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222467"} {"pmid": "4222468", "title": "Quinethazone photosensitivity dermatitis.", "content": "Quinethazone photosensitivity dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222468"} {"pmid": "4222469", "title": "Corynebacterium acnes. Presence of complement fixing antibodies to corynebacterium acnes in the sera of patients with acne vulgaris.", "content": "Corynebacterium acnes. Presence of complement fixing antibodies to corynebacterium acnes in the sera of patients with acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222469"} {"pmid": "4222471", "title": "Fungi in nails.", "content": "Fungi in nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222471"} {"pmid": "4222473", "title": "Recovery of muscle spindle activity in cats after cerebellar ablation.", "content": "Recovery of muscle spindle activity in cats after cerebellar ablation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222473"} {"pmid": "4222474", "title": "Workmen's compensation--a long journey forward.", "content": "Workmen's compensation--a long journey forward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222474"} {"pmid": "4222475", "title": "Proteolytic activity in muscles of old animals.", "content": "Proteolytic activity in muscles of old animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222475"} {"pmid": "4222481", "title": "Rapid separation of mucopolysaccharides by salt-gradient ion-exchange paper chromatography.", "content": "Rapid separation of mucopolysaccharides by salt-gradient ion-exchange paper chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222481"} {"pmid": "4222480", "title": "Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium.", "content": "Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium. Payne, W. J. (University of Georgia, Athens), and R. L. Todd. Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium. J. Bacteriol. 91:1533-1536. 1966.-Cell-free extracts of bacterium TEG-5 grown on tetraethylene glycol dehydrogenated a variety of ether glycols and nonylphenoxy and secondary alcohol ethoxy derivatives. Nicotinamide nucleotides did not serve as electron acceptors, but ferricyanide was effective. Dialysis of crude extract depressed activity with tetraethylene glycol, which was restored then by flavine adenine dinucleotide (FAD) or boiled extract supernatant fluid (BES) but not by other flavins. Precipitatation of extract protein at pH 4.0 at 80% ammonium sulfate saturation dissociated FAD and yielded an inactive fraction. Activity was restorable by FAD and BES but not by other flavins. Ethylene glycol was not dehydrogenated by the acid ammonium sulfate fraction with FAD. Atabrine inhibited tetraethylene glycol oxidation, and the inhibition was relieved by FAD but not by other flavins. Tergitols which have sulfated ethoxy side chains on secondary alcohols were not dehydrogenated, but those with free ethoxy side chains on identical alcohols were.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222480"} {"pmid": "4222483", "title": "Pediatric dentistry under general anesthesia.", "content": "Pediatric dentistry under general anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222483"} {"pmid": "4222482", "title": "Adenosine triphosphatase activity in 2 strains of Staphylococcus aureus differing in radiosensitivity.", "content": "Adenosine triphosphatase activity in 2 strains of Staphylococcus aureus differing in radiosensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222482"} {"pmid": "4222484", "title": "Symposium: Analgesia in dental practice. 4. Analgesia in pedodontic practice.", "content": "Symposium: Analgesia in dental practice. 4. Analgesia in pedodontic practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222484"} {"pmid": "4222486", "title": "Judicial vs. medical notice: coronary artery disease in industry.", "content": "Judicial vs. medical notice: coronary artery disease in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222486"} {"pmid": "4222487", "title": "The electromyogram in the evaluation of medicolegal and workmen's compensation cases.", "content": "The electromyogram in the evaluation of medicolegal and workmen's compensation cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222487"} {"pmid": "4222489", "title": "Principles of public health importance in the management of a subhuman primate colony.", "content": "Principles of public health importance in the management of a subhuman primate colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222489"} {"pmid": "4222490", "title": "Schistosome dermatitis in association with rice growing in the northern territory of Australia.", "content": "Schistosome dermatitis in association with rice growing in the northern territory of Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222490"} {"pmid": "4222496", "title": "Wheelchair users--a study in variation of disability.", "content": "Wheelchair users--a study in variation of disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222496"} {"pmid": "4222498", "title": "The pattern of contact dermatitis due to occupation.", "content": "The pattern of contact dermatitis due to occupation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222498"} {"pmid": "4222500", "title": "Hexosephosphate formation and the regulation of glycolysis in muscle.", "content": "Hexosephosphate formation and the regulation of glycolysis in muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222500"} {"pmid": "4222507", "title": "Influence of induced tuberculin allergy followed by induced Arthus reaction on each other, in rabbits.", "content": "Influence of induced tuberculin allergy followed by induced Arthus reaction on each other, in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222507"} {"pmid": "4222508", "title": "Coupling of ATP-hydrolysis with contraction of isolated myofibrillar fragments.", "content": "Coupling of ATP-hydrolysis with contraction of isolated myofibrillar fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222508"} {"pmid": "4222523", "title": "The effects of ethyl chloride on the muscle spindles of the triceps surae of the rabbit.", "content": "The effects of ethyl chloride on the muscle spindles of the triceps surae of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222523"} {"pmid": "4222524", "title": "Kurloff body formation in the guinea pig lymphocyte.", "content": "Kurloff body formation in the guinea pig lymphocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222524"} {"pmid": "4222533", "title": "Influence of rifamycins on glycolysis of rat brain.", "content": "Influence of rifamycins on glycolysis of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222533"} {"pmid": "4222532", "title": "Structure of heparitin sulfate in tissues of the Hurler syndrome.", "content": "Structure of heparitin sulfate in tissues of the Hurler syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222532"} {"pmid": "4222535", "title": "Effects of ethanol on na, K, mg-stimulated microsomal ATPase activity.", "content": "Effects of ethanol on na, K, mg-stimulated microsomal ATPase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222535"} {"pmid": "4222536", "title": "Adenosinetriphosphatase activity in synaptic vesicles of rat brain.", "content": "Adenosinetriphosphatase activity in synaptic vesicles of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222536"} {"pmid": "4222537", "title": "Inhibition of testosterone stimulation of microsomal hexobarbital metabolism by 17-alpha-methyl-B-nortestosterone (SK&F 7690).", "content": "Inhibition of testosterone stimulation of microsomal hexobarbital metabolism by 17-alpha-methyl-B-nortestosterone (SK&F 7690).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222537"} {"pmid": "4222538", "title": "Preventable occupational dermatoses.", "content": "Preventable occupational dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222538"} {"pmid": "4222539", "title": "The family physician and Workmen's Compensation. Legal aspects.", "content": "The family physician and Workmen's Compensation. Legal aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222539"} {"pmid": "4222540", "title": "Disability without disease or accident.", "content": "Disability without disease or accident.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222540"} {"pmid": "4222543", "title": "Study on frequency of allergic manifestations and skin reactivity in children with Down's syndrome.", "content": "Study on frequency of allergic manifestations and skin reactivity in children with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222543"} {"pmid": "4222544", "title": "Protein metabolism requisite for cell division in Tetrahymena pyriformis.", "content": "Protein metabolism requisite for cell division in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222544"} {"pmid": "4222564", "title": "Lipolytic activity of rat lungs in dependence on age.", "content": "Lipolytic activity of rat lungs in dependence on age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222564"} {"pmid": "4222565", "title": "The development of arginase and ornithine-transcarbamylase activities in the liver of rats.", "content": "The development of arginase and ornithine-transcarbamylase activities in the liver of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222565"} {"pmid": "4222566", "title": "Changes of proteolytic activity of proteins following denervation in the anterior and posterior latissimus dorsi of the chicken.", "content": "Changes of proteolytic activity of proteins following denervation in the anterior and posterior latissimus dorsi of the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222566"} {"pmid": "4222567", "title": "The effect of adrenalectomy and starvation on arginase and ornithine-transcarbamylase activities in the liver of rats during development.", "content": "The effect of adrenalectomy and starvation on arginase and ornithine-transcarbamylase activities in the liver of rats during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222567"} {"pmid": "4222568", "title": "Liberation from and uptake of non-esterified fatty acids into adipose tissue of rats with different work output.", "content": "Liberation from and uptake of non-esterified fatty acids into adipose tissue of rats with different work output.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222568"} {"pmid": "4222569", "title": "Vesico-ureteral reflux in rabbits.", "content": "Vesico-ureteral reflux in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222569"} {"pmid": "4222570", "title": "The relation between spontaneous rhythmical variation in vasomotor excitability and conditioning of the vasomotor reflex to deep inspiration.", "content": "The relation between spontaneous rhythmical variation in vasomotor excitability and conditioning of the vasomotor reflex to deep inspiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222570"} {"pmid": "4222571", "title": "Development of the steady potential and high frequency impedance of the cerebral cortex in guinea-pig embryos.", "content": "Development of the steady potential and high frequency impedance of the cerebral cortex in guinea-pig embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222571"} {"pmid": "4222572", "title": "A contribution to the analysis of the pulse rate during a load and recovery.", "content": "A contribution to the analysis of the pulse rate during a load and recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222572"} {"pmid": "4222573", "title": "The relationship between calcium and chlortetracycline in the body.", "content": "The relationship between calcium and chlortetracycline in the body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222573"} {"pmid": "4222574", "title": "Retraction and firmness of the fibrin clot.", "content": "Retraction and firmness of the fibrin clot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222574"} {"pmid": "4222575", "title": "Factors affecting the proteolytic activity in denervated muscle.", "content": "Factors affecting the proteolytic activity in denervated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222575"} {"pmid": "4222577", "title": "Rehabilitation of the disabled worker. I. An overall view of rehabilitation and workmen's compensation in New Jersey.", "content": "Rehabilitation of the disabled worker. I. An overall view of rehabilitation and workmen's compensation in New Jersey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222577"} {"pmid": "4222580", "title": "Pathological studies on mucopolysaccharide metabolism: experimental lathyrism and mucopolysaccharides.", "content": "Pathological studies on mucopolysaccharide metabolism: experimental lathyrism and mucopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222580"} {"pmid": "4222587", "title": "Efficacy of 'dequinol' in the treatment of bovine balantidiosis.", "content": "Efficacy of 'dequinol' in the treatment of bovine balantidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222587"} {"pmid": "4222588", "title": "Determination of glucosamine and galactosamine by gas chromatography.", "content": "Determination of glucosamine and galactosamine by gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222588"} {"pmid": "4222589", "title": "Effect of metal-complexing agents on mucopolysaccharide sulfate biosynthesis.", "content": "Effect of metal-complexing agents on mucopolysaccharide sulfate biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222589"} {"pmid": "4222591", "title": "The relation between DNA and protein synthesis in mouse fibroblasts.", "content": "The relation between DNA and protein synthesis in mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222591"} {"pmid": "4222593", "title": "Rehabilitation of the elderly patient.", "content": "Rehabilitation of the elderly patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222593"} {"pmid": "4222594", "title": "The impaired aged. A follow-up study of applicants rejected by a voluntary home.", "content": "The impaired aged. A follow-up study of applicants rejected by a voluntary home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222594"} {"pmid": "4222595", "title": "Seborrhoeic dermatitis.", "content": "Seborrhoeic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222595"} {"pmid": "4222610", "title": "Mucopolysaccharides in synovial fluid detection of chondroitin sulphate.", "content": "Mucopolysaccharides in synovial fluid detection of chondroitin sulphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222610"} {"pmid": "4222620", "title": "Effect of a sulfated mucopolysaccharide (R01-8307) on the zona glomerulosa of the rat adrenal gland.", "content": "Effect of a sulfated mucopolysaccharide (R01-8307) on the zona glomerulosa of the rat adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222620"} {"pmid": "4222622", "title": "Urinary acid mucopolysaccharides.", "content": "Urinary acid mucopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222622"} {"pmid": "4222625", "title": "Influence of a cartilage bone marrow extract on mucopolysaccharide metabolism of cells cultured in vitro.", "content": "Influence of a cartilage bone marrow extract on mucopolysaccharide metabolism of cells cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222625"} {"pmid": "4222624", "title": "Comparison of therapeutically important antirheumatics on the basis of experimental results.", "content": "Comparison of therapeutically important antirheumatics on the basis of experimental results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222624"} {"pmid": "4222626", "title": "Reproductive biology--2000.", "content": "Reproductive biology--2000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222626"} {"pmid": "4222627", "title": "The peptides of amniotic fluid.", "content": "The peptides of amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222627"} {"pmid": "4222628", "title": "Nebraska history and medicine: A centennial.", "content": "Nebraska history and medicine: A centennial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222628"} {"pmid": "4222629", "title": "The causes of labor.", "content": "The causes of labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222629"} {"pmid": "4222630", "title": "Evaluation of the fetus in utero.", "content": "Evaluation of the fetus in utero.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222630"} {"pmid": "4222631", "title": "Cellular production of gonadal steroid hormones.", "content": "Cellular production of gonadal steroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222631"} {"pmid": "4222632", "title": "Ultrasound in physiotherapy.", "content": "Ultrasound in physiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222632"} {"pmid": "4222639", "title": "Vitamin C deficiency and connective tissue. V. Fractionation of acid mucopolysaccharides in carrageenan-granulomas.", "content": "Vitamin C deficiency and connective tissue. V. Fractionation of acid mucopolysaccharides in carrageenan-granulomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222639"} {"pmid": "4222641", "title": "Our experience with the diagnosis of anomalies of the pulmonary venous return and their surgical treatment.", "content": "Our experience with the diagnosis of anomalies of the pulmonary venous return and their surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222641"} {"pmid": "4222640", "title": "Vitamin C deficiency and connective tissue. IV. Determinations of mucopolysaccharides and collagen in carrageenan-granulomas.", "content": "Vitamin C deficiency and connective tissue. IV. Determinations of mucopolysaccharides and collagen in carrageenan-granulomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222640"} {"pmid": "4222642", "title": "Isolated (primary) chylopericardium. Diagnosis and surgical treatment.", "content": "Isolated (primary) chylopericardium. Diagnosis and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222642"} {"pmid": "4222643", "title": "Dogger Bank itch: survey of trawlermen.", "content": "Dogger Bank itch: survey of trawlermen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222643"} {"pmid": "4222644", "title": "Arsenicals for asthma.", "content": "Arsenicals for asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222644"} {"pmid": "4222645", "title": "An inhibitor of cholesterol biosynthesis and the alveolar macrophages.", "content": "An inhibitor of cholesterol biosynthesis and the alveolar macrophages. An accumulation of lipid material was observed in the alveolar macrophages of animals treated per os with an inhibitor of cholesterol biosynthesis (trans-1, 4-bis) (2-dichlorobenzyl-aminomethyl) cyclohexane dihydrochloride: AY-9944). This lipid is probably 7-dehydro-cholesterol which is a precursor of cholesterol and accumulates in various organs, especially in the lungs. In the rats and pigs the reaction is limited to the alveolar macrophages which are expectorated or degenerate. In dogs some of the alveolar macrophages are also expectorated while others continue to collect a cholesterol-like lipid until large crystals form, which provoke the formation of giant cells and later fibrocytes, giving rise to \"cholesterol granulomata\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222645"} {"pmid": "4222646", "title": "Feed manufacturers and the veterinarian.", "content": "Feed manufacturers and the veterinarian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222646"} {"pmid": "4222648", "title": "The role of the food and drug directorate in the control of veterinary drugs.", "content": "The role of the food and drug directorate in the control of veterinary drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222648"} {"pmid": "4222647", "title": "Immunofluorescence study of wild rabies virus and antibody.", "content": "Immunofluorescence study of wild rabies virus and antibody. A concentrate of wild rabies antibody was prepared from hyperimmune serums of three dogs refractory to wild rabies. The animals resisted repeated intramuscular injections of large doses of wild rabies virus in emulsions of whole brain, in emulsions of submaxillary salivary glands, and in emulsified mixtures of brain and submaxillary glands taken from naturally rabid dogs. The antibody was conjugated with fluorochrome and then absorbed by a procedure that gave \"cell-free\" working solutions of fluorescent antibody. The procedure entailed parallel absorption steps with minced pathological canine submaxillary glands from (1) naturally rabid dogs (these glands contained specific, undegraded, natural antigens of live wild rabies virus plus nonspecific substances and antigens) and (2) nonrabid dogs from a rabies endemic region (these glands contained nonspecific substances and antigens). Extracts from submaxillary glands of the three naturally rabid dogs and one nonrabid dog were stained with a cell-free solution of the fluorescent antibody. The glands of the rabid dogs contained fluorescent aggregates of intense green spherical and filamentous particles. When nonfluorescent canine hyperimmune serum was incubated with rabies-containing submaxillary extract, the rabies antigens were quenched. When nonfluorescent equine fixed virus antiserum was incubated with such extracts, the aggregates still retained bright fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222647"} {"pmid": "4222650", "title": "Psychology of children's dental treatment.", "content": "Psychology of children's dental treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222650"} {"pmid": "4222651", "title": "Pedodontics--a graduate discipline.", "content": "Pedodontics--a graduate discipline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222651"} {"pmid": "4222652", "title": "Disabled children and rehabilitation.", "content": "Disabled children and rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222652"} {"pmid": "4222656", "title": "Orthodontics, pedodontics and the general practitioner.", "content": "Orthodontics, pedodontics and the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222656"} {"pmid": "4222657", "title": "Development of the resistance to general stagnant anoxia (ischemia) in dogs.", "content": "Development of the resistance to general stagnant anoxia (ischemia) in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222657"} {"pmid": "4222659", "title": "Human low-dosage parenteral methotrexate therapy. A controlled toxicity study.", "content": "Human low-dosage parenteral methotrexate therapy. A controlled toxicity study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222659"} {"pmid": "4222660", "title": "The use of gas-liquid chromatography in the analysis of neutral monosaccharides in hydrolysates of gastric mucopolysaccharides.", "content": "The use of gas-liquid chromatography in the analysis of neutral monosaccharides in hydrolysates of gastric mucopolysaccharides. 1. Conditions are described for the separation and estimation of the neutral monosaccharides obtained on acidic hydrolysis of human gastric mucopolysaccharides. 2. The technique involves the formation of the trimethylsilyl derivatives of the sugars and the analysis of these by gas-liquid chromatography. 3. The monosaccharides estimated in gastric mucopolysaccharides by this technique were l-fucose, d-mannose, d-galactose and d-glucose. 4. The analytical values for glucose and fucose obtained by this method agreed well with values obtained by the glucose oxidase and thioglycollic acid methods respectively. 5. Evidence is presented which clearly indicates that gas-liquid chromatography is a faster, more sensitive and more convenient technique for the measurement of these compounds than any other in use at present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222660"} {"pmid": "4222662", "title": "Why the Apollo contamination control handbook?", "content": "Why the Apollo contamination control handbook?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222662"} {"pmid": "4222664", "title": "Is your cleaning solvent compatible? Asks speaker.", "content": "Is your cleaning solvent compatible? Asks speaker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222664"} {"pmid": "4222661", "title": "Distribution of sodium-plus-potassium-stimulated adenosine-triphosphatase activity in isolated nerve-ending particles.", "content": "Distribution of sodium-plus-potassium-stimulated adenosine-triphosphatase activity in isolated nerve-ending particles. 1. A rapid method for the isolation of nerve-ending particles from brain is described. This involved the centrifugation of the large-granule fraction over a discontinuous density gradient consisting of 3% (w/v) and 13% (w/v) Ficoll dissolved in 0.32m-sucrose. The results of the biochemical as well as morphological identification of nerve-ending particles are given. 2. Approx. 20% of the (Na(+)+K(+))-stimulated adenosine-triphosphatase activity originally present in the cerebral grey-matter suspension was recovered in the fraction consisting principally of large nerve-ending particles (approx. 1mu in diameter). The activity of the adenosine triphosphatase/mg. of protein in the nerve-ending fraction approximated to that in the small-granule fraction after the treatment with glycol ether diamine-tetra-acetic acid. The conclusion was drawn that the synaptic structure, supposedly the limiting membrane of the nerve-ending particle, is one of the feasible sites of localization of the (Na(+)+K(+))-stimulated adenosine-triphosphatase activity in cerebral tissues. Adenosine triphosphatase in purified cerebral mitochondria was not stimulated by Na(+). 3. No qualitative differences were found between the (Na(+)+K(+))-stimulated adenosine-triphosphatase activities exhibited by the nerve-ending particles and by the cerebral small-granule fraction with respect to pH-dependence, cation requirements and susceptibility to ouabain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222661"} {"pmid": "4222663", "title": "Open-end clean room at Collins Radio flexible, expandable and economical.", "content": "Open-end clean room at Collins Radio flexible, expandable and economical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222663"} {"pmid": "4222665", "title": "Applying \"downflow\" to dust-fume control in a plastics facility.", "content": "Applying \"downflow\" to dust-fume control in a plastics facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222665"} {"pmid": "4222666", "title": "Contamination control for a precision photogrammetric lab.", "content": "Contamination control for a precision photogrammetric lab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222666"} {"pmid": "4222667", "title": "Understanding fluctuations in airborne contamination.", "content": "Understanding fluctuations in airborne contamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222667"} {"pmid": "4222668", "title": "Hospital use of sterile \"patient isolators\".", "content": "Hospital use of sterile \"patient isolators\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222668"} {"pmid": "4222669", "title": "Maximizing functional abilities of the disabled.", "content": "Maximizing functional abilities of the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222669"} {"pmid": "4222670", "title": "An endogenous mechanism of increased vascular permeability in allergic inflammation: purification of permeability factors newly isolated from Arthus lesion and their biologic significance.", "content": "An endogenous mechanism of increased vascular permeability in allergic inflammation: purification of permeability factors newly isolated from Arthus lesion and their biologic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222670"} {"pmid": "4222671", "title": "An endogenous mechanism of increased vascular permeability in allergic inflammation: reproduction of vascular response by Arthus permeability factor in rabbit skin.", "content": "An endogenous mechanism of increased vascular permeability in allergic inflammation: reproduction of vascular response by Arthus permeability factor in rabbit skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222671"} {"pmid": "4222674", "title": "p-Aminohippurate and N-methylnicotinamide transport in dog renal slices--an evaluation of the counter-transport hypothesis.", "content": "p-Aminohippurate and N-methylnicotinamide transport in dog renal slices--an evaluation of the counter-transport hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222674"} {"pmid": "4222675", "title": "The mechanism of reflex irradiation.", "content": "The mechanism of reflex irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222675"} {"pmid": "4222678", "title": "Measurement of plasma 11-deoxy-17-ketosteroid sulfates by gas-liquid chromatography.", "content": "Measurement of plasma 11-deoxy-17-ketosteroid sulfates by gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222678"} {"pmid": "4222677", "title": "Biosynthesis of steroid sulfates by normal human testis.", "content": "Biosynthesis of steroid sulfates by normal human testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222677"} {"pmid": "4222683", "title": "Changing concepts in pedodontic education.", "content": "Changing concepts in pedodontic education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222683"} {"pmid": "4222685", "title": "The production of phage structural proteins in single cells of Escherichia coli infected with phage T4.", "content": "The production of phage structural proteins in single cells of Escherichia coli infected with phage T4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222685"} {"pmid": "4222691", "title": "Intensive care of the coronary patient.", "content": "Intensive care of the coronary patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222691"} {"pmid": "4222692", "title": "Roentgenologic contrast studies in vascular disease.", "content": "Roentgenologic contrast studies in vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222692"} {"pmid": "4222693", "title": "Psychoactive drugs: review and overview. Review of sites of action, uses, dosage, side effects and contraindications of psychoactive drugs with proposed classification and suggested rules for prescribing.", "content": "Psychoactive drugs: review and overview. Review of sites of action, uses, dosage, side effects and contraindications of psychoactive drugs with proposed classification and suggested rules for prescribing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222693"} {"pmid": "4222694", "title": "The role of pelvic lymphadenectomy in the surgical management of early stage 1 carcinoma of the cervix.", "content": "The role of pelvic lymphadenectomy in the surgical management of early stage 1 carcinoma of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222694"} {"pmid": "4222695", "title": "Severe bronchial asthma: its pathology and treatment.", "content": "Severe bronchial asthma: its pathology and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222695"} {"pmid": "4222697", "title": "Tetanus.", "content": "Tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222697"} {"pmid": "4222696", "title": "Electrocardiogram of the month.", "content": "Electrocardiogram of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222696"} {"pmid": "4222698", "title": "Blood pressure and toxemia of pregnancy.", "content": "Blood pressure and toxemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222698"} {"pmid": "4222699", "title": "Do not despair.", "content": "Do not despair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222699"} {"pmid": "4222700", "title": "Pharmacologic interference with mast cell degranulation induced by BW 48/80.", "content": "Pharmacologic interference with mast cell degranulation induced by BW 48/80.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222700"} {"pmid": "4222706", "title": "Modern management of hair and scalp disorders.", "content": "Modern management of hair and scalp disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222706"} {"pmid": "4222709", "title": "An investigation into the content of elastic tissue and muscle tissue in the aorta of some big and small mammals.", "content": "An investigation into the content of elastic tissue and muscle tissue in the aorta of some big and small mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222709"} {"pmid": "4222712", "title": "The influence of new guanidine derivatives on adrenergic nerve endings, ganglionic transmission and neuromuscular junction.", "content": "The influence of new guanidine derivatives on adrenergic nerve endings, ganglionic transmission and neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222712"} {"pmid": "4222713", "title": "Potentiated premedication with ataraxics prior to stomatologic treatment of children and adolescents with psychiatric symptomatology. (Preliminary report).", "content": "Potentiated premedication with ataraxics prior to stomatologic treatment of children and adolescents with psychiatric symptomatology. (Preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222713"} {"pmid": "4222719", "title": "Plasminogen-free proactivator B obtained from human plasma.", "content": "Plasminogen-free proactivator B obtained from human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222719"} {"pmid": "4222721", "title": "Stimulation of the coronary collateral circulation by lidoflazine (R 7904).", "content": "Stimulation of the coronary collateral circulation by lidoflazine (R 7904).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222721"} {"pmid": "4222732", "title": "The antagonistic effects of sodium and calcium on the action potential of guinea pig papillary muscle.", "content": "The antagonistic effects of sodium and calcium on the action potential of guinea pig papillary muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222732"} {"pmid": "4222749", "title": "Skin disease in the Venda.", "content": "Skin disease in the Venda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222749"} {"pmid": "4222750", "title": "Receptor potentials and impulse generation in the isolated spindle during controlled extension.", "content": "Receptor potentials and impulse generation in the isolated spindle during controlled extension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222750"} {"pmid": "4222752", "title": "Response of the isolated muscle spindle to different rates of stretching.", "content": "Response of the isolated muscle spindle to different rates of stretching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222752"} {"pmid": "4222751", "title": "The dual role of sensory systems: detection and setting central excitability.", "content": "The dual role of sensory systems: detection and setting central excitability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222751"} {"pmid": "4222755", "title": "Technique for separation and estimation of androsterone, aetiocholanolone and dehydroepiandrosterone by use of thin-layer chromatography.", "content": "Technique for separation and estimation of androsterone, aetiocholanolone and dehydroepiandrosterone by use of thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222755"} {"pmid": "4222757", "title": "Some aspects of the aetiology of acne vulgris.", "content": "Some aspects of the aetiology of acne vulgris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222757"} {"pmid": "4222758", "title": "Occupational and nonoccupational exposures to asbestos.", "content": "Occupational and nonoccupational exposures to asbestos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222758"} {"pmid": "4222759", "title": "Dust diseases and workmen's compensation. U.S. Department of Labor, Bureau of Labor Standards, August 1964.", "content": "Dust diseases and workmen's compensation. U.S. Department of Labor, Bureau of Labor Standards, August 1964.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222759"} {"pmid": "4222761", "title": "Amino acid metabolism in patients with Hurler's syndrome.", "content": "Amino acid metabolism in patients with Hurler's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222761"} {"pmid": "4222762", "title": "Release of plasminogen activator by the isolated perfused dog kidney.", "content": "Release of plasminogen activator by the isolated perfused dog kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222762"} {"pmid": "4222765", "title": "The future of pedodontics.", "content": "The future of pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222765"} {"pmid": "4222766", "title": "Preparation of the specialists in pedodontics.", "content": "Preparation of the specialists in pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222766"} {"pmid": "4222767", "title": "Hospital procedures in the care of the handicapped child.", "content": "Hospital procedures in the care of the handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222767"} {"pmid": "4222768", "title": "An injection procedure for the child dental patient.", "content": "An injection procedure for the child dental patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222768"} {"pmid": "4222769", "title": "Rubber dam technique in pedodontics.", "content": "Rubber dam technique in pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222769"} {"pmid": "4222770", "title": "Stainless steel: its use in pedodontics.", "content": "Stainless steel: its use in pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222770"} {"pmid": "4222771", "title": "Plastics in pedodontics.", "content": "Plastics in pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222771"} {"pmid": "4222772", "title": "Pulpal therapy in primaryand young permanent teeth.", "content": "Pulpal therapy in primaryand young permanent teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222772"} {"pmid": "4222773", "title": "Traumatized primary teeth.", "content": "Traumatized primary teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222773"} {"pmid": "4222774", "title": "Pediatric exodontia.", "content": "Pediatric exodontia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222774"} {"pmid": "4222775", "title": "Treatment of dentitions affected by hereditary amelogenesis and dentinogenesis imperfecta.", "content": "Treatment of dentitions affected by hereditary amelogenesis and dentinogenesis imperfecta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222775"} {"pmid": "4222776", "title": "The versatile occlusal dental x-ray film. 3. A new pedodontic survey.", "content": "The versatile occlusal dental x-ray film. 3. A new pedodontic survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222776"} {"pmid": "4222777", "title": "A new cortical area receiving input from group I muscle afferents.", "content": "A new cortical area receiving input from group I muscle afferents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222777"} {"pmid": "4222778", "title": "Alkylation of a brain transport adenosinetriphosphatase at the cardiotonic steroid site by strophanthidin-3-haloacetates.", "content": "Alkylation of a brain transport adenosinetriphosphatase at the cardiotonic steroid site by strophanthidin-3-haloacetates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222778"} {"pmid": "4222779", "title": "6-alpha-hydroxylation in human placenta perfusion.", "content": "6-alpha-hydroxylation in human placenta perfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222779"} {"pmid": "4222780", "title": "Conversion of dehydroepiandrosterone sulfate to androst-5-enediol-3-sulfate by soluble extracts of rat testis.", "content": "Conversion of dehydroepiandrosterone sulfate to androst-5-enediol-3-sulfate by soluble extracts of rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222780"} {"pmid": "4222781", "title": "Natriuretic action of certain adrenocortical androgens.", "content": "Natriuretic action of certain adrenocortical androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222781"} {"pmid": "4222785", "title": "Some problems encountered in the assay of complement.", "content": "Some problems encountered in the assay of complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222785"} {"pmid": "4222786", "title": "Crystallization of the Dick toxin.", "content": "Crystallization of the Dick toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222786"} {"pmid": "4222790", "title": "Sodium-potassium dependent adenosine triphosphatase of mammalian reticulocytes and mature red blood cells.", "content": "Sodium-potassium dependent adenosine triphosphatase of mammalian reticulocytes and mature red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222790"} {"pmid": "4222791", "title": "In vitro testosterone synthesis by rat testicular tissue.", "content": "In vitro testosterone synthesis by rat testicular tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222791"} {"pmid": "4222792", "title": "Newborn organ abnormalities. A guide to abnormal maternal glucose metabolism.", "content": "Newborn organ abnormalities. A guide to abnormal maternal glucose metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222792"} {"pmid": "4222795", "title": "Pedodontic utilization of contributions made by operative dentistry, dental materials, and prosthodontics.", "content": "Pedodontic utilization of contributions made by operative dentistry, dental materials, and prosthodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222795"} {"pmid": "4222798", "title": "N-Hydroxylation of 2-aminofluorene in the guinea pig and by guinea pig liver microsomes in vitro.", "content": "N-Hydroxylation of 2-aminofluorene in the guinea pig and by guinea pig liver microsomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222798"} {"pmid": "4222794", "title": "Investigation of certain links in the photoenzymochemical chain of processes in photoreceptors.", "content": "Investigation of certain links in the photoenzymochemical chain of processes in photoreceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222794"} {"pmid": "4222804", "title": "The hydrolysis of acetanilide and some of its derivatives by enzymes in the microsomal and soluble fraction prepared from livers of various species.", "content": "The hydrolysis of acetanilide and some of its derivatives by enzymes in the microsomal and soluble fraction prepared from livers of various species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222804"} {"pmid": "4222818", "title": "Local authority welfare services for the handicapped.", "content": "Local authority welfare services for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222818"} {"pmid": "4222817", "title": "Viral-induced bacterial toxins.", "content": "Viral-induced bacterial toxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222817"} {"pmid": "4222819", "title": "Congenital beta-lipoprotein deficiency.", "content": "Congenital beta-lipoprotein deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222819"} {"pmid": "4222822", "title": "The XXXXY chromosome anomaly: report of three new cases and review of 30 cases from the literature.", "content": "The XXXXY chromosome anomaly: report of three new cases and review of 30 cases from the literature. The majority of abnormal sex chromosome complexes in the male have been considered to be variants of Klinefelter's syndrome but an exception should probably be made in the case of the XXXXY individual who has distinctive phenotypic features. Clinical, radiological and cytological data on three new cases of XXXXY syndrome are presented and 30 cases from the literature are reviewed. In many cases the published clinical and radiological data were supplemented and re-evaluated. Mental retardation, usually severe, was present in all cases. Typical facies was observed in many; clinodactyly of the fifth finger was seen in nearly all.Radiological examination revealed abnormalities in the elbows and wrists in all the 19 personally evaluated cases, and other skeletal anomalies were very frequent. Cryptorchism is very common and absence of Leydig's cells may differentiate the XXXXY chromosome anomaly from polysomic variants of Klinefelter's syndrome. The relationship of this syndrome to Klinefelter's syndrome and to Down's syndrome is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222822"} {"pmid": "4222824", "title": "Federal legislation and the smaller health care facility. More and better services needed for the physically disabled.", "content": "Federal legislation and the smaller health care facility. More and better services needed for the physically disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222824"} {"pmid": "4222823", "title": "The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man.", "content": "The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man. The mechanisms of the aldosterone-inhibiting and antihypertensive actions of heparin and certain other sulfated mucopolysaccharides were investigated in 13 hypertensive patients. N-formyl chitosan polysulfuric acid (RO 1-8307) was used rather than heparin because of its low anticoagulant activity. RO 1-8307 lowered aldosterone secretion in one patient with proved and one with probable primary aldosteronism; this indicates that the mucopolysaccharide does not inhibit aldosterone secretion via the renin-angiotensin mechanism. In six hypertensive patients RO 1-8307 caused a fall in the secretion of aldosterone and its probable immediate precursor, 18-hydroxycorticosterone; therefore it does not act at the last step in the synthesis of aldosterone. RO 1-8307 produced a prolonged clinical and biochemical remission in the two patients considered to have primary aldosteronism but did not influence blood pressure in five of seven patients in whom excessive aldosterone was probably not a major factor in the hypertension. It is concluded that the antihypertensive action of RO 1-8307, and perhaps of heparin as well, is largely due to suppression of aldosterone secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222823"} {"pmid": "4222825", "title": "Enzymes leading to mucopolysaccharide synthesis in granulation tissue.", "content": "Enzymes leading to mucopolysaccharide synthesis in granulation tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222825"} {"pmid": "4222836", "title": "Histochemical studies on the growing human tibial cartilage.", "content": "Histochemical studies on the growing human tibial cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222836"} {"pmid": "4222859", "title": "Silent period in patients with parkinsonian rigidity.", "content": "Silent period in patients with parkinsonian rigidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222859"} {"pmid": "4222863", "title": "Histological characteristics of mesothelioma associated with asbestos.", "content": "Histological characteristics of mesothelioma associated with asbestos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222863"} {"pmid": "4222864", "title": "Active transport and enzymes of the erythrocyte membrane under protein deprivation.", "content": "Active transport and enzymes of the erythrocyte membrane under protein deprivation. 1. Starvation for 3 days causes membrane damage of the rat erythrocyte manifested by several alterations. The adenosine-triphosphatase activity is decreased but that of acetylcholinesterase is not affected. 2. The ouabain-sensitive adenosine-triphosphatase activity increases at the expense of the non-sensitive enzyme moiety. 3. The Rb(+) uptake is not altered but the galactose transport is accelerated by the stated experimental conditions. 4. The modifications induced by starvation do not recover on re-feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222864"} {"pmid": "4222867", "title": "Temperate phages influencing lipase production by Staphylococcus aureus.", "content": "Temperate phages influencing lipase production by Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222867"} {"pmid": "4222869", "title": "Possible relationship between aortic acid mucopolysaccharides and species-susceptibility to experimental atherosclerosis.", "content": "Possible relationship between aortic acid mucopolysaccharides and species-susceptibility to experimental atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222869"} {"pmid": "4222874", "title": "Newer fibrinolytic agents.", "content": "Newer fibrinolytic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222874"} {"pmid": "4222877", "title": "Biochemical studies in Huntington's chorea. II. Composition of blood lipids.", "content": "Biochemical studies in Huntington's chorea. II. Composition of blood lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222877"} {"pmid": "4222878", "title": "1-Phosphofructokinase from an anaerobe.", "content": "1-Phosphofructokinase from an anaerobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222878"} {"pmid": "4222879", "title": "The occurrence of gamma-aminobutyric acid in human tissues other than brain.", "content": "The occurrence of gamma-aminobutyric acid in human tissues other than brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222879"} {"pmid": "4222880", "title": "A peculiar mode of muscular innervation in Amphioxus. Light and electron microscopic studies of the so-called ventral roots.", "content": "A peculiar mode of muscular innervation in Amphioxus. Light and electron microscopic studies of the so-called ventral roots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222880"} {"pmid": "4222883", "title": "In vitro susceptibility of UC-18 staphylococci.", "content": "In vitro susceptibility of UC-18 staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222883"} {"pmid": "4222882", "title": "Action of 5-fluorodeoxyuridine on human chromosomes.", "content": "Action of 5-fluorodeoxyuridine on human chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222882"} {"pmid": "4222885", "title": "Megaloblastic anaemia developing during treatment of epilepsy.", "content": "Megaloblastic anaemia developing during treatment of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222885"} {"pmid": "4222886", "title": "Mucopolysaccharides as a localized factor of egg-shell stability.", "content": "Mucopolysaccharides as a localized factor of egg-shell stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222886"} {"pmid": "4222887", "title": "ATP-ase as inhibitor of lysokinase and plasminoplastin activators of fibrinolysis in vitro.", "content": "ATP-ase as inhibitor of lysokinase and plasminoplastin activators of fibrinolysis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222887"} {"pmid": "4222888", "title": "Sulphate conjugation during development, in human, rat and guinea pig.", "content": "Sulphate conjugation during development, in human, rat and guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222888"} {"pmid": "4222889", "title": "Sulphate conjugation during pregnancy and under the influence of cortisone.", "content": "Sulphate conjugation during pregnancy and under the influence of cortisone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222889"} {"pmid": "4222944", "title": "Compensable psychogenic backache.", "content": "Compensable psychogenic backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222944"} {"pmid": "4222945", "title": "The effect of alum-precipitated pyridine ragweed extract on guinea pigs. II. Comparison of passive cutaneous anaphylaxis with Arthus reactivity after single low dose.", "content": "The effect of alum-precipitated pyridine ragweed extract on guinea pigs. II. Comparison of passive cutaneous anaphylaxis with Arthus reactivity after single low dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222945"} {"pmid": "4222947", "title": "Clinical manifestations of strongyloidiasis.", "content": "Clinical manifestations of strongyloidiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222947"} {"pmid": "4222946", "title": "The Brenner tumor.", "content": "The Brenner tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222946"} {"pmid": "4222948", "title": "Electrocardiogram of the month.", "content": "Electrocardiogram of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222948"} {"pmid": "4222949", "title": "The treatment of acne.", "content": "The treatment of acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222949"} {"pmid": "4222960", "title": "Specific reaction of local anesthetics with phosphodiester groups.", "content": "Specific reaction of local anesthetics with phosphodiester groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222960"} {"pmid": "4222959", "title": "7-alpha-hydroxylation of delta-5-pregnenolone and of its conjugates by rat-liver microsomes.", "content": "7-alpha-hydroxylation of delta-5-pregnenolone and of its conjugates by rat-liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222959"} {"pmid": "4222961", "title": "Does squinting matter?", "content": "Does squinting matter?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222961"} {"pmid": "4222962", "title": "Schooling for the handicapped.", "content": "Schooling for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222962"} {"pmid": "4222963", "title": "Studying 16,000 children.", "content": "Studying 16,000 children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222963"} {"pmid": "4222957", "title": "Research studies in physical fitness as applied to atypical youth.", "content": "Research studies in physical fitness as applied to atypical youth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222957"} {"pmid": "4222964", "title": "Comparative responses of regulative and determinate embryos to metabolic inhibitors.", "content": "Comparative responses of regulative and determinate embryos to metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222964"} {"pmid": "4222965", "title": "In vitro studies on 35S-sulfate incorporation into the acid mucopolysaccharides of chick embryo cardiac jelly.", "content": "In vitro studies on 35S-sulfate incorporation into the acid mucopolysaccharides of chick embryo cardiac jelly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222965"} {"pmid": "4222966", "title": "Acid mucopolysaccharide content of the cardiac jelly of the chick embryo.", "content": "Acid mucopolysaccharide content of the cardiac jelly of the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222966"} {"pmid": "4222968", "title": "Gene and phenocopy: selection experiments and tests with 6-aminonicotinamide.", "content": "Gene and phenocopy: selection experiments and tests with 6-aminonicotinamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222968"} {"pmid": "4222967", "title": "Differentiation of transplanted larval salivary glands of Drosophila hydei in adults of the same species.", "content": "Differentiation of transplanted larval salivary glands of Drosophila hydei in adults of the same species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222967"} {"pmid": "4222970", "title": "\"One's\" therapy of seborrheic dermatitis.", "content": "\"One's\" therapy of seborrheic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222970"} {"pmid": "4222971", "title": "Seborrheic dermatitis.", "content": "Seborrheic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222971"} {"pmid": "4222972", "title": "Current topical therapy for acne vulgaris.", "content": "Current topical therapy for acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222972"} {"pmid": "4222973", "title": "Fundamentals in acne management.", "content": "Fundamentals in acne management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222973"} {"pmid": "4222974", "title": "Current embryology and treatment of gastroschisis and omphalocele.", "content": "Current embryology and treatment of gastroschisis and omphalocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222974"} {"pmid": "4222975", "title": "Correlation between staphylococcal serotypes with 263-1 factor and phage group 1.", "content": "Correlation between staphylococcal serotypes with 263-1 factor and phage group 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222975"} {"pmid": "4222977", "title": "Excitation-contraction coupling and control of cardiac contractility.", "content": "Excitation-contraction coupling and control of cardiac contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222977"} {"pmid": "4222976", "title": "An attempt at biochemical characterisation of histologically well defined tumours.", "content": "An attempt at biochemical characterisation of histologically well defined tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222976"} {"pmid": "4222978", "title": "Demonstration of intercoronary anastomoses in human hearts with a low viscosity perfusion mass.", "content": "Demonstration of intercoronary anastomoses in human hearts with a low viscosity perfusion mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222978"} {"pmid": "4222980", "title": "Quantitative and qualitative cytochemical studies on the Amphiuma basophil leucocyte.", "content": "Quantitative and qualitative cytochemical studies on the Amphiuma basophil leucocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222980"} {"pmid": "4222981", "title": "Stoichiometry of proton translocation through the respiratory chain and adenosine triphosphatase systems of rat liver mitochondria.", "content": "Stoichiometry of proton translocation through the respiratory chain and adenosine triphosphatase systems of rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222981"} {"pmid": "4222982", "title": "Case records of the Massachusetts General Hospital. Case 31-1966.", "content": "Case records of the Massachusetts General Hospital. Case 31-1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222982"} {"pmid": "4222985", "title": "Assessment of disability.", "content": "Assessment of disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222985"} {"pmid": "4222986", "title": "Compensation to nurse for herniated disk.", "content": "Compensation to nurse for herniated disk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222986"} {"pmid": "4222988", "title": "Cardiac impulse in hypertrophic obstructive cardiomyopathy.", "content": "Cardiac impulse in hypertrophic obstructive cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222988"} {"pmid": "4222989", "title": "The effect of bile salts on oxygen consumption, oxidative phosphorylation and ATP-ase activity of mucosal homogenates from rat jejunum and ileum.", "content": "The effect of bile salts on oxygen consumption, oxidative phosphorylation and ATP-ase activity of mucosal homogenates from rat jejunum and ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222989"} {"pmid": "4222990", "title": "An oral digit symbol test.", "content": "An oral digit symbol test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222990"} {"pmid": "4222991", "title": "The Knox cubes as a test of memory and intelligence with male adults.", "content": "The Knox cubes as a test of memory and intelligence with male adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222991"} {"pmid": "4222993", "title": "Leukocyte alkaline phosphatase in mongolism.", "content": "Leukocyte alkaline phosphatase in mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222993"} {"pmid": "4222994", "title": "Control of myocardial contraction: the sensitivity of cardiac actomyosin to calcium ion.", "content": "Control of myocardial contraction: the sensitivity of cardiac actomyosin to calcium ion. The control by calcium ion of the adenosine triphosphatase activity of cardiac actomyosin is similar to that of white skeletal actomyosin. This finding indicates that the slower contraction and relaxation of heart muscle do not reflect different levels to which free calcium ion concentration around the myofibrils must be adjusted during contraction and relaxation and suggests a mechanism whereby myocardial contractility may be regulated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222994"} {"pmid": "4222996", "title": "Low back pain in men receiving workmen's compensation.", "content": "Low back pain in men receiving workmen's compensation. In Ontario, only about 10% of compensation patients with low back pain are disabled more than six weeks and hence tend to have chronic complaints. Six hundred and twenty-three such patients were studied to determine the distribution of diagnoses and to test the effectiveness of various programs of conservative therapy.Two hundred and thirteen patients were assigned in rotation to one of four treatments. The results were inconclusive. In 70% of these, the pain was due to intervertebral disc degeneration with added trauma.Two hundred and sixteen patients were assigned randomly to a treatment involving mild exercise, or one with vigorous exercise. Neither was found to be superior. In 76% of these, the pain was due to disc degeneration with added trauma.Using 194 patients, the results of treatment in the Compensation Board Rehabilitation Centre were compared with those obtained by treatment at home. Satisfactory improvement was achieved in 15 of 95 treated at home, and in 42 of 99 in the Centre. The failure of treatment in six of each 10 cases indicates that present-day methods of management of such patients are unsatisfactory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222996"} {"pmid": "4222995", "title": "Role of the B-complex vitamins on intestinal activity in dogs.", "content": "Role of the B-complex vitamins on intestinal activity in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222995"} {"pmid": "4222997", "title": "1965 achievements of Workmen's Compensation Board reviewed.", "content": "1965 achievements of Workmen's Compensation Board reviewed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222997"} {"pmid": "4222998", "title": "Effect of vitamin A on mucopolysaccharides in myxovirus-infected cells.", "content": "Effect of vitamin A on mucopolysaccharides in myxovirus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4222998"} {"pmid": "4223000", "title": "Early developmental staging as a prophecy index in Down's syndrome.", "content": "Early developmental staging as a prophecy index in Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223000"} {"pmid": "4223001", "title": "Alzheimer's disease and senile dementia as seen in mongoloids: neuropathological observations.", "content": "Alzheimer's disease and senile dementia as seen in mongoloids: neuropathological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223001"} {"pmid": "4223002", "title": "Mosaicism in Down's syndrome: studies in a child with an unusual chromosome constitution.", "content": "Mosaicism in Down's syndrome: studies in a child with an unusual chromosome constitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223002"} {"pmid": "4223003", "title": "Down's syndrome associated with family history of malignancy in mothers of affected children.", "content": "Down's syndrome associated with family history of malignancy in mothers of affected children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223003"} {"pmid": "4223004", "title": "Reproductive performance of mothers of mongols.", "content": "Reproductive performance of mothers of mongols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223004"} {"pmid": "4223006", "title": "The role of dental auxiliaries in child dental health.", "content": "The role of dental auxiliaries in child dental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223006"} {"pmid": "4223005", "title": "Skin disease from colour developers.", "content": "Skin disease from colour developers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223005"} {"pmid": "4223007", "title": "Inhibition of cell division and cell elongation in higher plants by inhibitors of DNA synthesis.", "content": "Inhibition of cell division and cell elongation in higher plants by inhibitors of DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223007"} {"pmid": "4223008", "title": "The nature of inclusions in erythrocytes of turkeys treated with diethylstilbestrol.", "content": "The nature of inclusions in erythrocytes of turkeys treated with diethylstilbestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223008"} {"pmid": "4223009", "title": "Hepatitis attributed to sulfamethoxazole.", "content": "Hepatitis attributed to sulfamethoxazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223009"} {"pmid": "4223012", "title": "Myofibrillar adenosine triphosphatase activity of human heart tissue in congestive failure: effects of ouabain and calcium.", "content": "Myofibrillar adenosine triphosphatase activity of human heart tissue in congestive failure: effects of ouabain and calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223012"} {"pmid": "4223014", "title": "Diagnostic signs in compressive cardiac disorders. Constrictive pericarditis, pericardial effusion, and tamponade.", "content": "Diagnostic signs in compressive cardiac disorders. Constrictive pericarditis, pericardial effusion, and tamponade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223014"} {"pmid": "4223013", "title": "Inhibition of protein synthesis in cardiac hypertrophy and its relation to myocardial failure.", "content": "Inhibition of protein synthesis in cardiac hypertrophy and its relation to myocardial failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223013"} {"pmid": "4223015", "title": "Studies on the fibrinolytic enzyme system in obesity.", "content": "Studies on the fibrinolytic enzyme system in obesity. Plasma fibrinolytic activity, inhibitors of fibrinolysis, and fibrinogen were estimated in 34 subjects of varying ratio of observed to standard weight. The inverse relationship between fibrinolytic activity and the ratio of observed to standard weight was confirmed. No significant correlation was found between anti-plasmin or anti-urokinase and the ratio of observed to standard weight. It was therefore concluded that the decreased plasma fibrinolytic activity in obese subjects is due to decreased production of plasminogen activator rather than to excessive inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223015"} {"pmid": "4223016", "title": "Combined hypertrophy.", "content": "Combined hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223016"} {"pmid": "4223017", "title": "Exhaustion of atrial fibrillation in aneurysmatic dilatation of the left atrium.", "content": "Exhaustion of atrial fibrillation in aneurysmatic dilatation of the left atrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223017"} {"pmid": "4223018", "title": "Philosophy of operation and medical policy of the Meeting Street School.", "content": "Philosophy of operation and medical policy of the Meeting Street School.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223018"} {"pmid": "4223019", "title": "Special education for handicapped children--where and when to use it.", "content": "Special education for handicapped children--where and when to use it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223019"} {"pmid": "4223022", "title": "Massive pulmonary embolism. VI. Prevention by partial occlusion of the inferior vena cava.", "content": "Massive pulmonary embolism. VI. Prevention by partial occlusion of the inferior vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223022"} {"pmid": "4223026", "title": "Antibody types in experimental animals and their biologic properties.", "content": "Antibody types in experimental animals and their biologic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223026"} {"pmid": "4223027", "title": "Histochemical studies on the red, white and intermediate muscle fibers of some skeletal muscles. I. Succinic dehydrogenase activity and physiological function of intercostal muscle fibers.", "content": "Histochemical studies on the red, white and intermediate muscle fibers of some skeletal muscles. I. Succinic dehydrogenase activity and physiological function of intercostal muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223027"} {"pmid": "4223028", "title": "Histochemical studies on the red, white and intermediate muscle fibers of some skeletal mescles. II. The capillary distribution on three types of fibers of some skeletal muscles.", "content": "Histochemical studies on the red, white and intermediate muscle fibers of some skeletal mescles. II. The capillary distribution on three types of fibers of some skeletal muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223028"} {"pmid": "4223029", "title": "Electron microscopic studies on the tumor induced by adenovirus type 12.", "content": "Electron microscopic studies on the tumor induced by adenovirus type 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223029"} {"pmid": "4223030", "title": "Physical analysis of the energy transducing reaction in mitochondria.", "content": "Physical analysis of the energy transducing reaction in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223030"} {"pmid": "4223031", "title": "Multiple keratoacanthomata. Response of a case to systemic chemotherapy.", "content": "Multiple keratoacanthomata. Response of a case to systemic chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223031"} {"pmid": "4223035", "title": "A simple method for the determination of urinary dehydroepiandrosterone.", "content": "A simple method for the determination of urinary dehydroepiandrosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223035"} {"pmid": "4223036", "title": "Determination of androsterone and dehydroepiandrosterone sulfates in human serum by gas-liquid chromatography.", "content": "Determination of androsterone and dehydroepiandrosterone sulfates in human serum by gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223036"} {"pmid": "4223037", "title": "Microbiological formation of 3-beta,7-alpha,15-alpha-trihydroxyandrost-5-en-17-one.", "content": "Microbiological formation of 3-beta,7-alpha,15-alpha-trihydroxyandrost-5-en-17-one.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223037"} {"pmid": "4223040", "title": "Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals.", "content": "Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223040"} {"pmid": "4223044", "title": "The enzymic oxidation of thiols.", "content": "The enzymic oxidation of thiols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223044"} {"pmid": "4223043", "title": "The uncoupling of respiratory-chain phosphorylation by 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole.", "content": "The uncoupling of respiratory-chain phosphorylation by 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole. 1. 30mmum-4,5,6,7-Tetrachloro-2-trifluoromethylbenzimidazole (TTFB) uncouples respiratory-chain phosphorylation. The respiration rate of uncoupled mitochondria is significantly greater than the state 3 rate. Neither added orthophosphate nor ATP is required to sustain this rate. The oligomycin- and octylguanidine-induced inhibitions of respiration are relieved by uncoupling concentrations of TTFB. 2. Uncoupling concentrations of TTFB elicit a high adenosinetriphosphatase activity and inhibit the ATP-dependent succinate-linked reduction of NAD catalysed by submitochondrial particles from ox-heart mitochondria. 3. The action of TTFB is similar to that of 2,4-dinitrophenol. Evidence is presented which shows that it is the anionic forms of benzimidazoles and imidazoles, having the negative charge localized on the ring nitrogen atom, which are the effective uncoupling agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223043"} {"pmid": "4223048", "title": "Pseudodisc--the problem of backache.", "content": "Pseudodisc--the problem of backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223048"} {"pmid": "4223052", "title": "The effect of long-term ethionine treatment on the activity of the serum properdin in rats.", "content": "The effect of long-term ethionine treatment on the activity of the serum properdin in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223052"} {"pmid": "4223050", "title": "Effects of dinitrophenol and oligomycin on the coupling between anaerobic metabolism and anaerobic sodium transport by the isolated turtle bladder.", "content": "Effects of dinitrophenol and oligomycin on the coupling between anaerobic metabolism and anaerobic sodium transport by the isolated turtle bladder. Dinitrophenol (1 x 10(-5)M) has been found to inhibit anaerobic sodium transport by the isolated urinary bladder of the fresh water turtle. Concurrently, anaerobic glycolysis was stimulated markedly. However, tissue ATP levels diminished only modestly, remaining at approximately 75% of values observed under anaerobic conditions without DNP. The utilization of glucose (from endogenous glycogen) corresponded closely to that predicted from the molar quantities of lactate formed. Thus the glycolytic pathway was completed in the presence of DNP and if ATP were synthesized normally during glycolysis, synthesis should have been increased. On the other hand, the decrease in Na transport should have decreased ATP utilization. Oligomycin did not block sodium transport either aerobically or anaerobically, but ATP concentrations did decrease. When anaerobic glycolysis was blocked by iodoacetate, pyruvate did not sustain sodium transport thus suggesting that no electron acceptors were available in the system. Two explanations are entertained for the anaerobic effect of DNP: (a) Stimulation by DNP of plasma membrane as well as mitochondrial ATPase activity; (b) inhibition of a high energy intermediate derived from glycolytic ATP or from glycolysis per se. The arguments relevant to each possibility are presented in the text. Although definitive resolution is not possible, we believe that the data favor the hypothesis that there was a high energy intermediate in the anaerobic system and that this intermediate, rather than ATP, served as the immediate source of energy for the sodium pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223050"} {"pmid": "4223051", "title": "Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.", "content": "Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223051"} {"pmid": "4223053", "title": "Studies on the alteration of species-specific resistance by ethionine-induced inhibition of protein metabolism. 3. Infection experiments in rats with Teschen-disease virus.", "content": "Studies on the alteration of species-specific resistance by ethionine-induced inhibition of protein metabolism. 3. Infection experiments in rats with Teschen-disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223053"} {"pmid": "4223054", "title": "Ganglioside inhibition of blood group antibodies with special reference to blood group I.", "content": "Ganglioside inhibition of blood group antibodies with special reference to blood group I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223054"} {"pmid": "4223060", "title": "On measuring left ventricular volume.", "content": "On measuring left ventricular volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223060"} {"pmid": "4223061", "title": "The allosteric nature of substrate inhibition of insect actomyosin ATPase in presence of magnesium.", "content": "The allosteric nature of substrate inhibition of insect actomyosin ATPase in presence of magnesium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223061"} {"pmid": "4223062", "title": "Cardiac performance in heart-lung preparations of rats with experimental cardiac hypertrophy.", "content": "Cardiac performance in heart-lung preparations of rats with experimental cardiac hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223062"} {"pmid": "4223064", "title": "Plasma enzymes that release kinins.", "content": "Plasma enzymes that release kinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223064"} {"pmid": "4223066", "title": "Camping though handicapped.", "content": "Camping though handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223066"} {"pmid": "4223065", "title": "The haemophilic boy in school.", "content": "The haemophilic boy in school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223065"} {"pmid": "4223067", "title": "Unbinding the homebound.", "content": "Unbinding the homebound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223067"} {"pmid": "4223069", "title": "Influences of public health education.", "content": "Influences of public health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223069"} {"pmid": "4223068", "title": "An improved method for the determination of orthophosphate suitable for assay of adenosine triphosphatase activity.", "content": "An improved method for the determination of orthophosphate suitable for assay of adenosine triphosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223068"} {"pmid": "4223070", "title": "Controlled clinical trial of \"Atromid\" (androsterone with ethyl-p-chlorophenoxy-isobutyrate) and \"Persantin\" (dipyridamole) in cases of myocardial infarction.", "content": "Controlled clinical trial of \"Atromid\" (androsterone with ethyl-p-chlorophenoxy-isobutyrate) and \"Persantin\" (dipyridamole) in cases of myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223070"} {"pmid": "4223071", "title": "Urological management of paraplegic patients.", "content": "Urological management of paraplegic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223071"} {"pmid": "4223072", "title": "The protein nutritive quality of ikan bilis (Stolephorus spp.).", "content": "The protein nutritive quality of ikan bilis (Stolephorus spp.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223072"} {"pmid": "4223073", "title": "A study of the haemolysin test in the identification of V. Cholerae biotype, El Tor.", "content": "A study of the haemolysin test in the identification of V. Cholerae biotype, El Tor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223073"} {"pmid": "4223074", "title": "A study of the psychosomatic aspects of peptic ulcer.", "content": "A study of the psychosomatic aspects of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223074"} {"pmid": "4223075", "title": "The life cycles of nematodes parasitic in man: an evolutionary sequence.", "content": "The life cycles of nematodes parasitic in man: an evolutionary sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223075"} {"pmid": "4223063", "title": "My aching back.", "content": "My aching back.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223063"} {"pmid": "4223081", "title": "Evaluation of abdominal decompression during the first stage of labor.", "content": "Evaluation of abdominal decompression during the first stage of labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223081"} {"pmid": "4223082", "title": "Acid mucopolysaccharides and cirrhosis of the liver.", "content": "Acid mucopolysaccharides and cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223082"} {"pmid": "4223083", "title": "Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet.", "content": "Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223083"} {"pmid": "4223084", "title": "The roentgenographic features of the KS mucopolysaccharidosis of Morquio (Morquio-Brailsford's disease).", "content": "The roentgenographic features of the KS mucopolysaccharidosis of Morquio (Morquio-Brailsford's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223084"} {"pmid": "4223085", "title": "Effects of diazoxide administration on plasma glucose, insulin, and lipids in Von Gierke's disease.", "content": "Effects of diazoxide administration on plasma glucose, insulin, and lipids in Von Gierke's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223085"} {"pmid": "4223087", "title": "Rehabilitative nursing.", "content": "Rehabilitative nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223087"} {"pmid": "4223088", "title": "Dressing activities for disabled persons.", "content": "Dressing activities for disabled persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223088"} {"pmid": "4223089", "title": "Federally financed dental care; could Ohio dentists meet the challenge?", "content": "Federally financed dental care; could Ohio dentists meet the challenge?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223089"} {"pmid": "4223090", "title": "Prophylactic odontotomy: a review.", "content": "Prophylactic odontotomy: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223090"} {"pmid": "4223093", "title": "The enteric surface coat on cat intestinal microvilli.", "content": "The enteric surface coat on cat intestinal microvilli. The enteric microvilli of the cat, bat, and man are coated with a conspicuous layer composed of fine filaments radiating from the outer dense leaflet of the plasma membrane. This surface coat is prominent on the absorptive cells but is not so thick on the goblet and undifferentiated crypt cells. In other species the surface coat is poorly developed or inconsistent, but all intestinal microvilli have traces of such a coating over the tips and sides of the microvilli. Tissues prepared by the ordinary sectioning techniques for electron microscopy usually reveal this component when stained with uranyl acetate followed by lead staining. The surface coat is intensely periodic acid-Schiff (PAS) positive and reacts with Alcian blue or Hale's colloidal iron stain for acid mucopolysaccharide. It is also stained by toluidine blue at low pH. Repeated washings or incubation with various chemical agents have failed to remove or markedly alter the appearance of the coating, but extruded cells undergoing autolysis lose their surface coats. The stability, consistent presence, and intimate association of the mucopolysaccharide coat suggest that it may be an integral part of the plasmalemma rather than an \"extraneous coat.\"", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223093"} {"pmid": "4223094", "title": "Antibacterial management of infection due to gram-negative bacilli. 3. Use of ampicillin, the cephalosporins, spectinomycin, and chemotherapy.", "content": "Antibacterial management of infection due to gram-negative bacilli. 3. Use of ampicillin, the cephalosporins, spectinomycin, and chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223094"} {"pmid": "4223095", "title": "Self-adaptive control and respiratory system.", "content": "Self-adaptive control and respiratory system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223095"} {"pmid": "4223096", "title": "Nicotinamide mononucleotide pyrophosphorylase activity in ascites cell extracts.", "content": "Nicotinamide mononucleotide pyrophosphorylase activity in ascites cell extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223096"} {"pmid": "4223097", "title": "Incidence of disability in 1965.", "content": "Incidence of disability in 1965.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223097"} {"pmid": "4223098", "title": "Congenital anomalies of the abdominal musculature and urogenital tract in a foal.", "content": "Congenital anomalies of the abdominal musculature and urogenital tract in a foal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223098"} {"pmid": "4223099", "title": "Skin eruption in a patient receiving hemineurine.", "content": "Skin eruption in a patient receiving hemineurine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223099"} {"pmid": "4223102", "title": "Sulfhydryl groups involved in the active site of myosin A adenosine triphosphatase. I. Specific blocking of the SH group responsible for the inhibitory phase in \"B phasic response\" of the catalytic activity.", "content": "Sulfhydryl groups involved in the active site of myosin A adenosine triphosphatase. I. Specific blocking of the SH group responsible for the inhibitory phase in \"B phasic response\" of the catalytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223102"} {"pmid": "4223105", "title": "Testimony of employer's doctor admissible in workmen's compensation case.", "content": "Testimony of employer's doctor admissible in workmen's compensation case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223105"} {"pmid": "4223109", "title": "A medical history of poison ivy (Rhus toxicodendron).", "content": "A medical history of poison ivy (Rhus toxicodendron).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223109"} {"pmid": "4223113", "title": "Microscopic anatomy and histochemistry of glands in the external auditory meatus of the cat (Felis domesticus).", "content": "Microscopic anatomy and histochemistry of glands in the external auditory meatus of the cat (Felis domesticus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223113"} {"pmid": "4223115", "title": "Thin-layer chromatography and the rapid identification of common acidic glycosaminoglycans.", "content": "Thin-layer chromatography and the rapid identification of common acidic glycosaminoglycans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223115"} {"pmid": "4223116", "title": "Obesity and heart failure.", "content": "Obesity and heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223116"} {"pmid": "4223107", "title": "Sequential experimentation and multivariate analysis in the evaluation of a treatment for postoperative intestinal symptoms.", "content": "Sequential experimentation and multivariate analysis in the evaluation of a treatment for postoperative intestinal symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223107"} {"pmid": "4223117", "title": "The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinase.", "content": "The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinase. 1. A theoretical appraisal of the alternative pathway mechanism for a two-substrate enzyme shows that this mechanism is capable of giving rise to apparent substrate inhibition or substrate activation (Dalziel, 1958). It has now been shown that these phenomena may occur simultaneously in the following ways. With certain relationships between the kinetic parameters and the constant concentration of one substrate, A, the plot of initial rate, v, against the concentration of the other substrate, B, may show substrate ;activation' at low concentrations of B and substrate ;inhibition' at high concentrations of B. In other circumstances the plot of v against [B], with [A] constant, may be sigmoid (substrate activation), whereas the plot of v against [A], with [B] constant, may pass through a maximum (substrate inhibition). 2. Kinetic data for phosphofructokinase are of the latter type and it is suggested that the mechanism of this enzyme may involve a kinetically preferred pathway. It is emphasized that the phenomena of substrate inhibition and activation need not necessarily involve more than one binding site for each substrate on the enzyme molecule, nor more than one monomer per molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223117"} {"pmid": "4223118", "title": "Legal aspects of industrial immunization programs.", "content": "Legal aspects of industrial immunization programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223118"} {"pmid": "4223119", "title": "Referral to attorneys.", "content": "Referral to attorneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223119"} {"pmid": "4223121", "title": "Audiological assessment of a mongoloid population.", "content": "Audiological assessment of a mongoloid population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223121"} {"pmid": "4223122", "title": "Studies on progressive muscular dystrophy. I. Effects of adenosinetriphosphate and its related compounds on progressive muscular dystrophy.", "content": "Studies on progressive muscular dystrophy. I. Effects of adenosinetriphosphate and its related compounds on progressive muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223122"} {"pmid": "4223124", "title": "Another cause of low back pain: lipomata in the sacroiliac region.", "content": "Another cause of low back pain: lipomata in the sacroiliac region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223124"} {"pmid": "4223125", "title": "Fate of injected dehydroisoandrosterone, testosterone, and dehydroiisoandrosterone sulfate in plasma in the human.", "content": "Fate of injected dehydroisoandrosterone, testosterone, and dehydroiisoandrosterone sulfate in plasma in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223125"} {"pmid": "4223126", "title": "Aryl and steroid sulfatase in the human ovary.", "content": "Aryl and steroid sulfatase in the human ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223126"} {"pmid": "4223127", "title": "The stabilizing effect of neutral salts on plasmin.", "content": "The stabilizing effect of neutral salts on plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223127"} {"pmid": "4223129", "title": "A survey of Salmonella VI-phage types occurring in Federation of Malaya and Singapore.", "content": "A survey of Salmonella VI-phage types occurring in Federation of Malaya and Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223129"} {"pmid": "4223130", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1966.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223130"} {"pmid": "4223131", "title": "Pyogenic abdominal wall and psoas abscesses in children.", "content": "Pyogenic abdominal wall and psoas abscesses in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223131"} {"pmid": "4223133", "title": "Benzoyl peroxide and sulfur: foundation for acne management.", "content": "Benzoyl peroxide and sulfur: foundation for acne management. One hundred and thirteen consecutive patients with acne were studied by qualified dermatologists during a trial of topical 10% benzoyl peroxide and 2%-5% sulfur cream. The results were considered \"good\" to \"excellent\" in both office and clinic situations. The method was remarkably free of undesirable side effects. The program has been adopted as a standard acne regimen at the dermatology clinic of the Royal Victoria Hospital, Montreal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223133"} {"pmid": "4223134", "title": "Applicability of exfolative vaginal cytology in sexual hormonology.", "content": "Applicability of exfolative vaginal cytology in sexual hormonology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223134"} {"pmid": "4223135", "title": "Changing concepts in obstetrics.", "content": "Changing concepts in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223135"} {"pmid": "4223136", "title": "Comparative study of intrauterine contraceptive devices--spiral, loop, and ring.", "content": "Comparative study of intrauterine contraceptive devices--spiral, loop, and ring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223136"} {"pmid": "4223137", "title": "Labor management with unlimited clean vaginal examinations; a review of 4,537 cases.", "content": "Labor management with unlimited clean vaginal examinations; a review of 4,537 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223137"} {"pmid": "4223139", "title": "Sex health for college students.", "content": "Sex health for college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223139"} {"pmid": "4223138", "title": "Safety evaluation of an acid powder for routine vaginal cleansing.", "content": "Safety evaluation of an acid powder for routine vaginal cleansing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223138"} {"pmid": "4223140", "title": "Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.", "content": "Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223140"} {"pmid": "4223142", "title": "Vectorcardiographic signs of biventricular hypertrophy.", "content": "Vectorcardiographic signs of biventricular hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223142"} {"pmid": "4223150", "title": "Fractionation of urinary biocolloids in children and adults by gel filtration.", "content": "Fractionation of urinary biocolloids in children and adults by gel filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223150"} {"pmid": "4223153", "title": "A lymphocytosis-stimulating substance in Mongoloid plasma.", "content": "A lymphocytosis-stimulating substance in Mongoloid plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223153"} {"pmid": "4223154", "title": "Effect of a subcurative dose of TWSb on the levels of phosphate esters in Schistosoma mansoni.", "content": "Effect of a subcurative dose of TWSb on the levels of phosphate esters in Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223154"} {"pmid": "4223155", "title": "Adenosine-5'-sulfatopyrophosphate, an analogue of adenosine triphosphate. II. Interaction with myosin, actomyosin, and muscle fibers.", "content": "Adenosine-5'-sulfatopyrophosphate, an analogue of adenosine triphosphate. II. Interaction with myosin, actomyosin, and muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223155"} {"pmid": "4223156", "title": "Mechanism of the Crabtree effect in yeast grown with different glucose concentrations.", "content": "Mechanism of the Crabtree effect in yeast grown with different glucose concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223156"} {"pmid": "4223157", "title": "Effect of alloxan on mitochondrial adenosinetriphosphatase activity and the ATP-ADP exchange reaction.", "content": "Effect of alloxan on mitochondrial adenosinetriphosphatase activity and the ATP-ADP exchange reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223157"} {"pmid": "4223148", "title": "Introduction: mucopolysaccharides.", "content": "Introduction: mucopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223148"} {"pmid": "4223162", "title": "Effects of FUdR and thymidine on incorporation of deoxycytidine into DNA of Vicia faba.", "content": "Effects of FUdR and thymidine on incorporation of deoxycytidine into DNA of Vicia faba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223162"} {"pmid": "4223149", "title": "Very high molecular weight mucopolysaccharides and mucopolysaccharide-protein complexes--how far can we extrapolate?", "content": "Very high molecular weight mucopolysaccharides and mucopolysaccharide-protein complexes--how far can we extrapolate?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223149"} {"pmid": "4223170", "title": "Oxidative phosphorylation accompanying oxidation of short-chain fatty acids by rat-liver mitochondria.", "content": "Oxidative phosphorylation accompanying oxidation of short-chain fatty acids by rat-liver mitochondria. 1. The factors concerned in the estimation of P/O ratios when fatty acids are oxidized by rat-liver mitochondria have been assessed. 2. The oxidation of butyrate, hexanoate and octanoate is accompanied by ATP synthesis. At low concentrations of the fatty acids, P/O ratios approximately 2.5 are obtained. 3. Oxidative phosphorylation is uncoupled, respiratory control ratios are lowered and respiration is inhibited when the concentration of the fatty acid in the incubating medium is raised (to 5-10mm); octanoate is a more potent uncoupler than either hexanoate or butyrate. 4. Serum albumin and carnitine, either singly or in combination, protect the mitochondria from the effect exerted by the fatty acids. 5. The rate of oxidation of short-chain fatty acids in the presence of ADP is increased in the presence of carnitine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223170"} {"pmid": "4223164", "title": "The early fate of autogenous grafts in the canine femoral vein.", "content": "The early fate of autogenous grafts in the canine femoral vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223164"} {"pmid": "4223171", "title": "The action of neutral hypochlorite on epithelial mucopolysaccharides.", "content": "The action of neutral hypochlorite on epithelial mucopolysaccharides. 1. The uptake of dilute neutral hypochlorite by epithelial mucopolysaccharides has been compared with that of proteins, polysaccharides, amino acids and sugars. The uptake has been shown to be related to the protein content of the mucopolysaccharides rather than their polysaccharide content. 2. The destruction of the components of epithelial mucopolysaccharides, certain sugars and polysaccharides after oxidation with dilute neutral hypochlorite at 0-4 degrees has been studied. Very little destruction of the sugar components occurred and in epithelial mucopolysaccharides the only amino acid destroyed specifically was arginine. 3. Oxidation of bovine submaxillary-gland mucoprotein and ovalbumin caused very little destruction of hexosamine and no detectable liberation of this residue as a free reducing group, indicating that the O-seryl galactosaminide and the N-acyl-glycosylamine linkages reported to be present in these compounds were relatively stable to hypochlorite. 4. Depolymerization of epithelial mucopolysaccharides by neutral hypochlorite has been studied by using gel-filtration columns and compared with the depolymerization of polysaccharides and proteins under similar conditions. The polysaccharides examined were relatively resistant to oxidation whereas the proteins were extensively broken down. It is inferred that the extensive depolymerization of epithelial mucopolysaccharides by hypochlorite is related to their protein content rather than their polysaccharide content. 5. Fractionation of the products of oxidation of epithelial mucopolysaccharides by column procedures has revealed that the relative proportions of components in all fractions were similar to those in the original material. 6. Though this study does not provide unequivocal evidence from which the overall structure of this type of epithelial mucopolysaccharide may be deduced, the balance of probabilities now appears to favour a long polypeptide chain to which a large number of oligosaccharide side chains are attached via O-seryl and O-threonyl glycosidic linkages. The results, however, are also consistent with an alternating sequence of short polysaccharide and polypeptide chains and further evidence is necessary before this structure can be ruled out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223171"} {"pmid": "4223172", "title": "The effect of fasting on esterification of palmitate by rat liver in vitro.", "content": "The effect of fasting on esterification of palmitate by rat liver in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223172"} {"pmid": "4223175", "title": "Virulence and the biochemical characters of staphylococci.", "content": "Virulence and the biochemical characters of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223175"} {"pmid": "4223163", "title": "New, histological and biochemical, researches in experimentally induced arteriosclerosis.", "content": "New, histological and biochemical, researches in experimentally induced arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223163"} {"pmid": "4223177", "title": "On the pathomorphology of osteomyelosclerosis.", "content": "On the pathomorphology of osteomyelosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223177"} {"pmid": "4223178", "title": "Histochemistry of lipid metabolism in the liver of rabbits treated with chlortetracycline (CTC).", "content": "Histochemistry of lipid metabolism in the liver of rabbits treated with chlortetracycline (CTC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223178"} {"pmid": "4223180", "title": "The spread of non-tuberculous pulmonary diseases in Bulgaria.", "content": "The spread of non-tuberculous pulmonary diseases in Bulgaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223180"} {"pmid": "4223179", "title": "Susceptibility of tubercle myobacteria to antibacterial drugs and its importance for the clinical course of tuberculosis.", "content": "Susceptibility of tubercle myobacteria to antibacterial drugs and its importance for the clinical course of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223179"} {"pmid": "4223182", "title": "The environment: its role in surgical infections.", "content": "The environment: its role in surgical infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223182"} {"pmid": "4223190", "title": "Arteriography: an aid in the diagnosis of vascular disease.", "content": "Arteriography: an aid in the diagnosis of vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223190"} {"pmid": "4223191", "title": "Pregnancy and delivery following bilateral ureteral transplant to the bowl for exstrophy of the bladder. Report of a case.", "content": "Pregnancy and delivery following bilateral ureteral transplant to the bowl for exstrophy of the bladder. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223191"} {"pmid": "4223192", "title": "Progress in earlier recognition of breast cancer.", "content": "Progress in earlier recognition of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223192"} {"pmid": "4223193", "title": "Current acid-fast bacilli in Douglas County.", "content": "Current acid-fast bacilli in Douglas County.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223193"} {"pmid": "4223194", "title": "Neurologic manifestations of hyperpyrexia.", "content": "Neurologic manifestations of hyperpyrexia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223194"} {"pmid": "4223197", "title": "Voluntary service in child health and child care.", "content": "Voluntary service in child health and child care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223197"} {"pmid": "4223200", "title": "Facilities for the blind in Singapore.", "content": "Facilities for the blind in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223200"} {"pmid": "4223199", "title": "Intracellular autogenetic effects of muscular contration on extensor motoneurones. The silent period.", "content": "Intracellular autogenetic effects of muscular contration on extensor motoneurones. The silent period. 1. Intracellular records have been taken from cat motoneurones belonging to gastrocnemius and soleus or to popliteal synergists during contractions of gastrocnemius and soleus, acting separately or jointly. Such contractions were elicited by brief tetani or single shocks to the peripheral end of the cut ventral roots L7 or S1.2. Hyperpolarization of the motoneurone accompanies rise of tension in contraction. The amount of it increases when at constant extension the contraction of the muscle is increased by increasing stimulus strength, as well as when it is increased by augmenting extension at constant stimulus strength. It is therefore tension-sensitive.3. The duration of the hyperpolarization induced in this manner reflects the duration of the contraction itself, being considerably longer in the slow soleus than in the faster gastrocnemius. It is often preceded by a brief wavelet of depolarization ascribed to the so-called back-response.4. Early in relaxation there occurs a transient ;hump' of membrane depolarization. This corresponds to the moment characterized by phasic bursts from the spindle primaries. The ;hump' terminates hyperpolarization.5. When the cell is stimulated by injected current to maintained repetitive firing, the ;silent period' in contraction begins with the phase of hyperpolarization and ends with the hump of depolarization as described above.6. Later during relaxation, delayed inhibition, may or may not follow often accompanied by hyperpolarizing activation noise and sometimes also visible as an extension of the silent period of a firing cell. There is, however, no marked hyperpolarization of the motoneurone in delayed inhibition.7. In the Discussion the events described above are related to previous studies employing monosynaptic testing or electromyography for the analysis of the variations of excitability caused in extensor motoneurones by autogenetic contractions as well as to known properties of stretch receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223199"} {"pmid": "4223211", "title": "Systemic eczematous \"contact-type\" dermatitis medicamentosa.", "content": "Systemic eczematous \"contact-type\" dermatitis medicamentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223211"} {"pmid": "4223212", "title": "Dichlorophene allergy.", "content": "Dichlorophene allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223212"} {"pmid": "4223213", "title": "Copper poisoning in the snail Helix pomatia and its effect on mucous secretion.", "content": "Copper poisoning in the snail Helix pomatia and its effect on mucous secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223213"} {"pmid": "4223214", "title": "The anterior salivary gland of the octopus (Octopus vulgaris) and its mucous secretion.", "content": "The anterior salivary gland of the octopus (Octopus vulgaris) and its mucous secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223214"} {"pmid": "4223215", "title": "The presence of mucopolysaccharides in the hepatopancreas of the isopod, Armadillidium vulgare.", "content": "The presence of mucopolysaccharides in the hepatopancreas of the isopod, Armadillidium vulgare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223215"} {"pmid": "4223218", "title": "Interagency coordination. A basic need in serving handicapped children.", "content": "Interagency coordination. A basic need in serving handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223218"} {"pmid": "4223222", "title": "Activation and inhibition of myosin B adenosine triphosphatase by mg++ and ca++ at low concentration of KC1.", "content": "Activation and inhibition of myosin B adenosine triphosphatase by mg++ and ca++ at low concentration of KC1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223222"} {"pmid": "4223223", "title": "Optical rotatory dispersion and enzymic studies on the tryptic digestion of rabbit skeletal and cardiac myosins and their macromolecular fragments.", "content": "Optical rotatory dispersion and enzymic studies on the tryptic digestion of rabbit skeletal and cardiac myosins and their macromolecular fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223223"} {"pmid": "4223224", "title": "Bound adenosine diphosphate and adenosine triphosphate in resting and contracting muscle.", "content": "Bound adenosine diphosphate and adenosine triphosphate in resting and contracting muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223224"} {"pmid": "4223216", "title": "Inhibition of proteolytic enzymes by beta-lipoprotein.", "content": "Inhibition of proteolytic enzymes by beta-lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223216"} {"pmid": "4223227", "title": "Histochemical investigations on the behaviour of some enzymes in liver cells of the mouse under the influence of oestrogens. I. Alkaline phosphatase (ALP-ase), adenosinetriphosphatase (ATP-ase), acid phosphatase (AP-ase).", "content": "Histochemical investigations on the behaviour of some enzymes in liver cells of the mouse under the influence of oestrogens. I. Alkaline phosphatase (ALP-ase), adenosinetriphosphatase (ATP-ase), acid phosphatase (AP-ase).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223227"} {"pmid": "4223228", "title": "Repair of defects after partial resection of the abdominal wall.", "content": "Repair of defects after partial resection of the abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223228"} {"pmid": "4223217", "title": "Effects of MgEDTA on the mucopolysaccharide metabolism in the atherosclerotic aorta.", "content": "Effects of MgEDTA on the mucopolysaccharide metabolism in the atherosclerotic aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223217"} {"pmid": "4223239", "title": "Adenosine triphosphatase activity of adrenal medulla catecholamine granules.", "content": "Adenosine triphosphatase activity of adrenal medulla catecholamine granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223239"} {"pmid": "4223240", "title": "Accumulation of Ca2+ and Sr2+ by rat-liver mitochondria: preferential loss of the adenosine triphosphate-dependent mechanism for Sr2+ accumulation.", "content": "Accumulation of Ca2+ and Sr2+ by rat-liver mitochondria: preferential loss of the adenosine triphosphate-dependent mechanism for Sr2+ accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223240"} {"pmid": "4223241", "title": "The right ventricle and pulmonary vascular obstruction in bronchitis with emphysema.", "content": "The right ventricle and pulmonary vascular obstruction in bronchitis with emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223241"} {"pmid": "4223244", "title": "Cytochemical observations on chick liver cell cultures infected with Trichomonas vaginalis. 1. Nucleic acids, polysaccharides, lipids, and proteins.", "content": "Cytochemical observations on chick liver cell cultures infected with Trichomonas vaginalis. 1. Nucleic acids, polysaccharides, lipids, and proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223244"} {"pmid": "4223242", "title": "The electrocardiogram in chronic bronchitis and emphysema.", "content": "The electrocardiogram in chronic bronchitis and emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223242"} {"pmid": "4223245", "title": "Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. 1. Androgenic secretion as demonstrated by a bioindicator method.", "content": "Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. 1. Androgenic secretion as demonstrated by a bioindicator method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223245"} {"pmid": "4223238", "title": "Psychological correlates of the MFS rehabilitation rating scale.", "content": "Psychological correlates of the MFS rehabilitation rating scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223238"} {"pmid": "4223246", "title": "Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. II. Secretion of androgenic hormone in adrenals and testes during early stages of development.", "content": "Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. II. Secretion of androgenic hormone in adrenals and testes during early stages of development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223246"} {"pmid": "4223253", "title": "The occurrence of relaxing granules in the muscle of the locust, Locust migratoria.", "content": "The occurrence of relaxing granules in the muscle of the locust, Locust migratoria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223253"} {"pmid": "4223254", "title": "Anticoccidial activity of nicotinamide antagonists.", "content": "Anticoccidial activity of nicotinamide antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223254"} {"pmid": "4223264", "title": "The occurrence and mechanism of P-wave inversion in lead I in right atrial overloading. Report of two cases.", "content": "The occurrence and mechanism of P-wave inversion in lead I in right atrial overloading. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223264"} {"pmid": "4223265", "title": "Cardiomegaly in myxedema. Report of a case and review of the literature.", "content": "Cardiomegaly in myxedema. Report of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223265"} {"pmid": "4223266", "title": "Infant and child mortality in Burma by ethnic group.", "content": "Infant and child mortality in Burma by ethnic group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223266"} {"pmid": "4223267", "title": "Correlative study between electrocardiographic findings and ventricular wall thickness based on cardio-synchronous angiocardiography. I. Comparison of angiocardiographic and postmortem thickness of ventricular wall in normal dogs.", "content": "Correlative study between electrocardiographic findings and ventricular wall thickness based on cardio-synchronous angiocardiography. I. Comparison of angiocardiographic and postmortem thickness of ventricular wall in normal dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223267"} {"pmid": "4223268", "title": "Norepinephrine metabolism in hypertrophied rat hearts.", "content": "Norepinephrine metabolism in hypertrophied rat hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223268"} {"pmid": "4223269", "title": "Effect of carcinolipin on the adenosine triphosphatase activity of isolated cellular fractions.", "content": "Effect of carcinolipin on the adenosine triphosphatase activity of isolated cellular fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223269"} {"pmid": "4223271", "title": "Delineating the possible for the multi-handicapped child with visual impairment.", "content": "Delineating the possible for the multi-handicapped child with visual impairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223271"} {"pmid": "4223270", "title": "Hormonal regulation of cardiac muscle citrate.", "content": "Hormonal regulation of cardiac muscle citrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223270"} {"pmid": "4223282", "title": "Studies on vaccination against cholera. 3. Immune response in man.", "content": "Studies on vaccination against cholera. 3. Immune response in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223282"} {"pmid": "4223295", "title": "Heart size in pregnancy.", "content": "Heart size in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223295"} {"pmid": "4223298", "title": "Mycologic testing of soil samples from populated areas with endemic nephropathy.", "content": "Mycologic testing of soil samples from populated areas with endemic nephropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223298"} {"pmid": "4223300", "title": "On some metabolic and functional changes of the heart muscle in experimental myocarditis.", "content": "On some metabolic and functional changes of the heart muscle in experimental myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223300"} {"pmid": "4223301", "title": "Inquiries into the protein composition of the heart muscle in experimental myocarditis of dogs.", "content": "Inquiries into the protein composition of the heart muscle in experimental myocarditis of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223301"} {"pmid": "4223302", "title": "Intraparenchymal distribution of the blood vessels of the thyroid gland.", "content": "Intraparenchymal distribution of the blood vessels of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223302"} {"pmid": "4223303", "title": "Early results of antibacterial treatment of newly traced consumptive patients.", "content": "Early results of antibacterial treatment of newly traced consumptive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223303"} {"pmid": "4223309", "title": "The use of mathematical model in the study of the properties of the full-surface electrocardiogram. I: Scher generators in a homogeneous torso. II: \"Enlarged heart\" potentials.", "content": "The use of mathematical model in the study of the properties of the full-surface electrocardiogram. I: Scher generators in a homogeneous torso. II: \"Enlarged heart\" potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223309"} {"pmid": "4223311", "title": "Degradation of mucopolysaccharides by hepatic lysosomes.", "content": "Degradation of mucopolysaccharides by hepatic lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223311"} {"pmid": "4223313", "title": "Gas-liquid chromatographic separation of C19 and C21 human urinary steroids by a new procedure.", "content": "Gas-liquid chromatographic separation of C19 and C21 human urinary steroids by a new procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223313"} {"pmid": "4223314", "title": "O-t-c anti-acne aids.", "content": "O-t-c anti-acne aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223314"} {"pmid": "4223312", "title": "Inhibition by ergotamine and ergobasinine of Ca2+ uptake from the sarcotubular system.", "content": "Inhibition by ergotamine and ergobasinine of Ca2+ uptake from the sarcotubular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223312"} {"pmid": "4223315", "title": "The thymus and the tolerance function.", "content": "The thymus and the tolerance function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223315"} {"pmid": "4223317", "title": "Changes in biochemical properties of isolated human skeletal myofibrils with age and in Myasthenia gravis.", "content": "Changes in biochemical properties of isolated human skeletal myofibrils with age and in Myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223317"} {"pmid": "4223318", "title": "Studies on erythrocyte glycolysis. II. Free energy changes and rate limitings steps in erythrocyte glycolysis.", "content": "Studies on erythrocyte glycolysis. II. Free energy changes and rate limitings steps in erythrocyte glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223318"} {"pmid": "4223319", "title": "Studies on erythrocyte glycolysis. 3. The effects of active cation transport, pH and inorganic phosphate concentration on erythrocyte glycolysis.", "content": "Studies on erythrocyte glycolysis. 3. The effects of active cation transport, pH and inorganic phosphate concentration on erythrocyte glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223319"} {"pmid": "4223320", "title": "Superprecipitation of actomyosin reconstructed with F-actin and NEM-modified myosin.", "content": "Superprecipitation of actomyosin reconstructed with F-actin and NEM-modified myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223320"} {"pmid": "4223324", "title": "Two-year pedodontic internship residency program is approved.", "content": "Two-year pedodontic internship residency program is approved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223324"} {"pmid": "4223326", "title": "Pedodontics at Harvard.", "content": "Pedodontics at Harvard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223326"} {"pmid": "4223327", "title": "Dental plan for children urged by professor.", "content": "Dental plan for children urged by professor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223327"} {"pmid": "4223329", "title": "The forgotten 3 per cent in the dental office--care of the mentally retarded.", "content": "The forgotten 3 per cent in the dental office--care of the mentally retarded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223329"} {"pmid": "4223330", "title": "A Head Start to where?", "content": "A Head Start to where?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223330"} {"pmid": "4223331", "title": "Camping with the chronic sick.", "content": "Camping with the chronic sick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223331"} {"pmid": "4223328", "title": "Prosthetic service for pre school children.", "content": "Prosthetic service for pre school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223328"} {"pmid": "4223325", "title": "Dentistry and the handicapped child.", "content": "Dentistry and the handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223325"} {"pmid": "4223335", "title": "Morphological and histochemical studies of partially and totally deafferented spinal cord segments.", "content": "Morphological and histochemical studies of partially and totally deafferented spinal cord segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223335"} {"pmid": "4223343", "title": "\"Fear and anxiety in the dental chair\".", "content": "\"Fear and anxiety in the dental chair\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223343"} {"pmid": "4223344", "title": "Water fluoridation--its effect on pedodontics.", "content": "Water fluoridation--its effect on pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223344"} {"pmid": "4223355", "title": "The periodic synthesis of thymidine kinase in mouse fibroblasts.", "content": "The periodic synthesis of thymidine kinase in mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223355"} {"pmid": "4223356", "title": "Further observations on the physiology and pharmacology of elasmobranch ventricular fluid.", "content": "Further observations on the physiology and pharmacology of elasmobranch ventricular fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223356"} {"pmid": "4223357", "title": "Studies on sodium-potassium-activated adenosinetriphosphatase. XV. The rectal gland of the elasmobranchs.", "content": "Studies on sodium-potassium-activated adenosinetriphosphatase. XV. The rectal gland of the elasmobranchs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223357"} {"pmid": "4223345", "title": "A dental care plan for Michigan children.", "content": "A dental care plan for Michigan children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223345"} {"pmid": "4223361", "title": "Key figures in legislation for the handicapped.", "content": "Key figures in legislation for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223361"} {"pmid": "4223346", "title": "PRESCAD--what is it?", "content": "PRESCAD--what is it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223346"} {"pmid": "4223362", "title": "Abnormal response to anaesthesia in a case of Huntington's chorea.", "content": "Abnormal response to anaesthesia in a case of Huntington's chorea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223362"} {"pmid": "4223363", "title": "Mongolism, leukemia and sex chromatin anomalies.", "content": "Mongolism, leukemia and sex chromatin anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223363"} {"pmid": "4223365", "title": "The fibrinolytic enzyme system in physiological pregnancies at term and during labour.", "content": "The fibrinolytic enzyme system in physiological pregnancies at term and during labour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223365"} {"pmid": "4223366", "title": "Studies on hyaine membrane disease.3. Thrapeutic trial of urokinase-activated huma plasmin.", "content": "Studies on hyaine membrane disease.3. Thrapeutic trial of urokinase-activated huma plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223366"} {"pmid": "4223367", "title": "Angiocardiographic determination of the size of the left ventricle in congenital heart disease.", "content": "Angiocardiographic determination of the size of the left ventricle in congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223367"} {"pmid": "4223368", "title": "Painless chronic dissecting aneurysm of the aorta. Report of a case.", "content": "Painless chronic dissecting aneurysm of the aorta. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223368"} {"pmid": "4223370", "title": "The pre-steady state of the myosin--adenosine triphosphate system. IV. Liberation of ADP from the myosin--ATP system and effects of modifiers on the phosphorylation of myosin.", "content": "The pre-steady state of the myosin--adenosine triphosphate system. IV. Liberation of ADP from the myosin--ATP system and effects of modifiers on the phosphorylation of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223370"} {"pmid": "4223369", "title": "The adenosine diphosphate--adenosine triposphate-excange reaction of cerebral microsomes and its relation to he sodium ion-stimulatd adenosine-triphosphatase reaction.", "content": "The adenosine diphosphate--adenosine triposphate-excange reaction of cerebral microsomes and its relation to he sodium ion-stimulatd adenosine-triphosphatase reaction. Microsomes from guinea-pig cerebral cortex contain a system capable of exchanging ADP with ATP at rates of about 20mumoles/mg. of protein/hr. The ADP-ATP-exchange reaction requires Mg(2+) for activity. The reaction is not stimulated by Na(+) or K(+) and is not inhibited by ouabain, in contrast with the Na(+)-plus-K(+)-stimulated adenosine triphosphatase. The pH optimum also differs from that of the adenosine triphosphatase. The ADP-ATP-exchange reaction is stimulated two- to three-fold by non-ionic, anionic and cationic detergents, even when these agents are inhibiting the adenosine-triphosphatase reaction. This reaction may represent a component of the Na(+)-plus-K(+)-stimulated adenosine-triphosphatase reaction but is more likely to be due to other enzyme systems present in microsomal subfractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223369"} {"pmid": "4223371", "title": "Calcium-dependent granular adenosinetriphosphatase from glycerinated myofibrils.", "content": "Calcium-dependent granular adenosinetriphosphatase from glycerinated myofibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223371"} {"pmid": "4223372", "title": "Role of ADP bound to F-actin in superprecipitation and enzymatic activity of actomyosin.", "content": "Role of ADP bound to F-actin in superprecipitation and enzymatic activity of actomyosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223372"} {"pmid": "4223374", "title": "Inhibition of gastric secretion by fractionated lymph. Elaboration of gastrone-like substance during digestive phases in dogs.", "content": "Inhibition of gastric secretion by fractionated lymph. Elaboration of gastrone-like substance during digestive phases in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223374"} {"pmid": "4223375", "title": "An antithrombin (maculatin) and a plasminogen activator extractable from the blood-sucking hemipteran, Eutriatoma maculatus.", "content": "An antithrombin (maculatin) and a plasminogen activator extractable from the blood-sucking hemipteran, Eutriatoma maculatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223375"} {"pmid": "4223376", "title": "Studies of erythrocyte spicule formation in haemolytic anaemia.", "content": "Studies of erythrocyte spicule formation in haemolytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223376"} {"pmid": "4223377", "title": "Endotoxin shock in the New Zealand white rabbit. An evaluation of fibrinolysin therapy.", "content": "Endotoxin shock in the New Zealand white rabbit. An evaluation of fibrinolysin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223377"} {"pmid": "4223385", "title": "On some functional and histochemical changes in myocarditis of rabbits induced by streptolysine and A-group streptococci.", "content": "On some functional and histochemical changes in myocarditis of rabbits induced by streptolysine and A-group streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223385"} {"pmid": "4223392", "title": "Meiosis in trisomic Down's syndrome.", "content": "Meiosis in trisomic Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223392"} {"pmid": "4223394", "title": "Hygienic and experimental studies of the conditions of work and occupational morbidity in electric and gas welders.", "content": "Hygienic and experimental studies of the conditions of work and occupational morbidity in electric and gas welders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223394"} {"pmid": "4223396", "title": "Intrapericardial fat pads and anomalous development of the septum transversum as a cause of pseudocardiomegaly.", "content": "Intrapericardial fat pads and anomalous development of the septum transversum as a cause of pseudocardiomegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223396"} {"pmid": "4223397", "title": "Luetic aneurysms of the aortic valve, sinus of Valsalva, and aorta.", "content": "Luetic aneurysms of the aortic valve, sinus of Valsalva, and aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223397"} {"pmid": "4223398", "title": "Experimental retinal vein occlusion and treatment with fibrinolysin.", "content": "Experimental retinal vein occlusion and treatment with fibrinolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223398"} {"pmid": "4223399", "title": "Studies in sickle cell anemia. XXVII. Complications in infants and children in the United States.", "content": "Studies in sickle cell anemia. XXVII. Complications in infants and children in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223399"} {"pmid": "4223400", "title": "Rehabilitation of the injured worker.", "content": "Rehabilitation of the injured worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223400"} {"pmid": "4223402", "title": "Effect of hypertrophy on myocardial distensibility.", "content": "Effect of hypertrophy on myocardial distensibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223402"} {"pmid": "4223403", "title": "Chromosomes of \"mongoloid\" hamsters.", "content": "Chromosomes of \"mongoloid\" hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223403"} {"pmid": "4223404", "title": "Psychosomatic aspects of acne: a controlled study.", "content": "Psychosomatic aspects of acne: a controlled study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223404"} {"pmid": "4223405", "title": "Estimation of dehydroepiandrosterone sulfate in human serum by gas-liquid chromatography.", "content": "Estimation of dehydroepiandrosterone sulfate in human serum by gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223405"} {"pmid": "4223406", "title": "Estimation of trypsin in presence of plasmin and their separation by gel filtration.", "content": "Estimation of trypsin in presence of plasmin and their separation by gel filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223406"} {"pmid": "4223407", "title": "Effects of zinc on adenosine triphosphatase activity and superprecipitation of actomyosin from skeletal muscle of rabbit.", "content": "Effects of zinc on adenosine triphosphatase activity and superprecipitation of actomyosin from skeletal muscle of rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223407"} {"pmid": "4223408", "title": "Stimulation of Na+ and K+ dependent adenosine triphosphatase by ouabain.", "content": "Stimulation of Na+ and K+ dependent adenosine triphosphatase by ouabain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223408"} {"pmid": "4223409", "title": "Effects of preparations of heparin and heparitin sulfate on fibrinolysis.", "content": "Effects of preparations of heparin and heparitin sulfate on fibrinolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223409"} {"pmid": "4223410", "title": "Immunology and cancer.", "content": "Immunology and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223410"} {"pmid": "4223411", "title": "Psychologic aspect of ulcerative colitis in children.", "content": "Psychologic aspect of ulcerative colitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223411"} {"pmid": "4223412", "title": "Metabolic and statural response to human growth hormone in juvenile Cushing's syndrome with dwarfism.", "content": "Metabolic and statural response to human growth hormone in juvenile Cushing's syndrome with dwarfism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223412"} {"pmid": "4223413", "title": "Recent advances in treatment of the eye.", "content": "Recent advances in treatment of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223413"} {"pmid": "4223415", "title": "Controlled relaxation. I. Quantitation of electromyogram with abdominal relaxation.", "content": "Controlled relaxation. I. Quantitation of electromyogram with abdominal relaxation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223415"} {"pmid": "4223416", "title": "The \"butterfly\" eruption.", "content": "The \"butterfly\" eruption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223416"} {"pmid": "4223417", "title": "Dilatation of the heart.", "content": "Dilatation of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223417"} {"pmid": "4223420", "title": "Leftward shift of the terminal P forces in the ECG associated with left atrial enlargement.", "content": "Leftward shift of the terminal P forces in the ECG associated with left atrial enlargement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223420"} {"pmid": "4223421", "title": "Clinical pathologic conference.", "content": "Clinical pathologic conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223421"} {"pmid": "4223423", "title": "The action of ketonic prostaglandins on the guinea-pig myometrium.", "content": "The action of ketonic prostaglandins on the guinea-pig myometrium. 1. Prostaglandin E(1) or E(2) has two clearly distinguishable effects on the guinea-pig myometrium in vitro.2. The first of these, the ;direct' effect, is manifested by contraction accompanied by spiking, is readily modified by changes in the concentrations of Mg(2+), Ca(2+) and K(+) in the suspension medium, and does not long outlast the presence of the prostaglandin in the organ-bath. In this respect it resembles the responses to other stimulants.3. The second effect is manifested by ;enhancement' of the responses to non-specific stimulation, whether this be by chemical or electrical means. Enhancement may be demonstrated for up to 20-80 min after the PGE(1) or PGE(2) has been washed out of the organ-bath, and during this time the myometrium shows no consistent changes in electrical activity or in resting mechanical tension that may be associated with the enhancement effect. Enhancement following PGEs is not readily affected by moderate changes in the Mg(2+), Ca(2+) or K(+) concentrations of the suspension medium, and in all these respects it differs markedly from the effects of other stimulants.4. K(+)-depolarized myometrial preparations show feeble direct responses to PGEs, like those to other stimulants. They also show post-PGE enhancement of the responses to other stimulants, but not of the responses to electric field stimulation.5. The empirical method used for measuring the enhancement effect is examined critically.6. The possible mechanisms of the direct and enhancement effects are discussed. It is postulated that they involve actions at two different sites, which may be on two different types of cell but are more likely to co-exist on the same cells. The direct effect is postulated to result from depolarization at the exposed cell membrane, whereas enhancement may result from facilitation of excitation-contraction coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223423"} {"pmid": "4223426", "title": "Topical corticosteroids for skin disorders.", "content": "Topical corticosteroids for skin disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223426"} {"pmid": "4223424", "title": "The reflex response to sinusoidal stretching of soleus in the decerebrate cat.", "content": "The reflex response to sinusoidal stretching of soleus in the decerebrate cat. 1. Soleus muscle in the decerebrate cat was stretched sinusoidally through various distances, at various frequencies while tension and e.m.g. activity were recorded.2. Two patterns of stretch reflex activity were seen. In one, slow stretching led to a large increase in tension, whereas in the other tension increased little during slow stretching, but rose steeply during a more rapid stretch. Intermediate states were also seen.3. Both these reflex patterns were abolished when the fusimotor fibres were blocked with Xylocaine.4. At low frequencies of stretching the e.m.g. activity was greatest at peak muscle length; at higher frequencies the greatest activity was found during lengthening. This angular advance of e.m.g. activity on length was greatest at 3.3-5 c/s. At the higher frequencies the e.m.g. activity was less in advance of muscle length.5. Angular advance of e.m.g. activity was greatest in the preparations that were also the most sensitive to slow stretching.6. Muscle contraction follows an electrical stimulus with a small delay. The delay between the end of stimulation and the end of muscle relaxation is longer, and may exceed 200 msec in cat soleus.7. The timing of the reflex tension during sinusoidal stretching depended on how far the angular advance of the e.m.g. combined with the damping properties of muscle offset the time delays in the reflex pathway.8. Changes in muscle tension generally preceded changes in muscle length. When, however, stretch amplitudes of 1 mm (peak to peak) were used, a phase delay of tension was sometimes seen. This only occurred in preparations that also showed little sensitivity to slow stretching.9. Phase delay of tension was usually found with frequencies of approximately 6-8 c/s, and this corresponds to the clonus frequency for soleus.10. The mechanisms of the two types of reflex behaviour, and the damping properties of the system are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223424"} {"pmid": "4223425", "title": "Organization of neurones in the cat cerebral cortex that are influenced from group I muscle afferents.", "content": "Organization of neurones in the cat cerebral cortex that are influenced from group I muscle afferents. 1. Neurones in the Group I projection area of the first sensori-motor cortex were investigated with extra- and intracellular technique.2. The majority of the neurones influenced by volleys in Group I afferents of contralateral forelimb nerves received exclusively excitation, but some received exclusively inhibition, and some mixed excitation and inhibition.3. The Group I influenced cells were usually found 500-1500 mu beneath the cortical surface.4. The EPSPs and IPSPs evoked from Group I afferents had a steep rising phase and a slow, approximately exponential decay. The duration was sometimes more than 50 msec. The EPSP evoked by a maximal Group I volley was often formed by a small number of large unitary EPSPs.5. Latency measurements indicate that the majority of the Group I activated neurones were monosynaptically excited from the thalamic fibres, and hence constitute the fourth-order neurones in the Group I projection system. The latencies of the IPSPs suggest a disynaptic linkage with thalamic fibres. Hence, the exclusively inhibited cells would constitute fifth-order neurones. It is suggested that most or all of the fourth-order neurones are inhibitory.6. The convergence of excitation and/or inhibition to individual cells was usually extensive and included effects not only from muscle groups working at different joints but also effects from antagonistic groups at the same joint. In addition cutaneous afferents contributed synaptic actions which had a longer latency than the synaptic actions from Group I afferents.7. The neurones influenced from Group I afferents were not antidromically activated on stimulation of the pyramidal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223425"} {"pmid": "4223449", "title": "Congenital heart disease and pheochromocytoma.", "content": "Congenital heart disease and pheochromocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223449"} {"pmid": "4223450", "title": "Paternal transmission of a D/G translocation of Down's syndrome.", "content": "Paternal transmission of a D/G translocation of Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223450"} {"pmid": "4223451", "title": "Anodontia in mongolism.", "content": "Anodontia in mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223451"} {"pmid": "4223453", "title": "Differential diagnosis of visceral from somatic back pain.", "content": "Differential diagnosis of visceral from somatic back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223453"} {"pmid": "4223454", "title": "The action of cytostatic agents on the chromosomes of human leukocytes in vitro (preliminary communication).", "content": "The action of cytostatic agents on the chromosomes of human leukocytes in vitro (preliminary communication).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223454"} {"pmid": "4223456", "title": "Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. I. An associated sodium-activated transphosphorylation.", "content": "Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. I. An associated sodium-activated transphosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223456"} {"pmid": "4223457", "title": "Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. II. Effects of N-ethylmaleimide and other sulfhydryl reagents.", "content": "Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. II. Effects of N-ethylmaleimide and other sulfhydryl reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223457"} {"pmid": "4223452", "title": "Change in platelet antiplasm in activity following splenectomy.", "content": "Change in platelet antiplasm in activity following splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223452"} {"pmid": "4223462", "title": "Development of the steady potential of the brain of chick embryos.", "content": "Development of the steady potential of the brain of chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223462"} {"pmid": "4223463", "title": "Comparative pathophysiology of the paroxysmal electroencephalogram. Paroxysmal electroencephalogram (spike and wave activity) in the lizard (Lacerta agilis).", "content": "Comparative pathophysiology of the paroxysmal electroencephalogram. Paroxysmal electroencephalogram (spike and wave activity) in the lizard (Lacerta agilis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223463"} {"pmid": "4223465", "title": "Developmental changes in the protein composition of heart muscle in the rat.", "content": "Developmental changes in the protein composition of heart muscle in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223465"} {"pmid": "4223466", "title": "Adaptation of rats of different ages to forced intake of a 2 per cent NaC1 solution without the occurrence of salt hypertension.", "content": "Adaptation of rats of different ages to forced intake of a 2 per cent NaC1 solution without the occurrence of salt hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223466"} {"pmid": "4223467", "title": "The incorporation of S35 methionine into proteins of denervated and reinnervated muscle.", "content": "The incorporation of S35 methionine into proteins of denervated and reinnervated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223467"} {"pmid": "4223468", "title": "Optimum conditions for studying autoiodoproteolysis of 127-I-thyroglobulin in rats.", "content": "Optimum conditions for studying autoiodoproteolysis of 127-I-thyroglobulin in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223468"} {"pmid": "4223469", "title": "Changes in the protein content of plasma during blood losses in rats.", "content": "Changes in the protein content of plasma during blood losses in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223469"} {"pmid": "4223470", "title": "Changes in haemoglobin fractions separated on CM-sephadex in normal newborn rats and in newborn rats after repeated blood losses.", "content": "Changes in haemoglobin fractions separated on CM-sephadex in normal newborn rats and in newborn rats after repeated blood losses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223470"} {"pmid": "4223471", "title": "Studies on the glycoproteins of human seminal plasma.", "content": "Studies on the glycoproteins of human seminal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223471"} {"pmid": "4223472", "title": "Changes in the membrane potential of cortical cells during spreading depression.", "content": "Changes in the membrane potential of cortical cells during spreading depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223472"} {"pmid": "4223473", "title": "Decerebrate control of primary afferent depolarisation evoked by adequate stimulation of cutaneous receptors.", "content": "Decerebrate control of primary afferent depolarisation evoked by adequate stimulation of cutaneous receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223473"} {"pmid": "4223474", "title": "The effect of thalamic spreading depression on electric activity in the caudate nucleus and the hippocampus in rats.", "content": "The effect of thalamic spreading depression on electric activity in the caudate nucleus and the hippocampus in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223474"} {"pmid": "4223475", "title": "Optic evoked potentials in children, using different stimulation frequencies.", "content": "Optic evoked potentials in children, using different stimulation frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223475"} {"pmid": "4223476", "title": "The effect of increased sodium chloride intake on the rate of formation and retention of alimentary conditioned reflexes in normally and prematurely weaned rats.", "content": "The effect of increased sodium chloride intake on the rate of formation and retention of alimentary conditioned reflexes in normally and prematurely weaned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223476"} {"pmid": "4223477", "title": "Iodine, solid diet, water and milk intake by lactating rats and their offsprings.", "content": "Iodine, solid diet, water and milk intake by lactating rats and their offsprings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223477"} {"pmid": "4223478", "title": "The effect of thyroidectomy at early ontogenetic stages upon oxidative processes in the rat brain.", "content": "The effect of thyroidectomy at early ontogenetic stages upon oxidative processes in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223478"} {"pmid": "4223479", "title": "Fat content and lipoproteinase activity in muscles of male rats with increased or reduced motor activity.", "content": "Fat content and lipoproteinase activity in muscles of male rats with increased or reduced motor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223479"} {"pmid": "4223480", "title": "A comparison between 18 to 20-year-old students with average physique and trained individuals.", "content": "A comparison between 18 to 20-year-old students with average physique and trained individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223480"} {"pmid": "4223481", "title": "Development of the relationship between aerobic capacity and the circulatory and respiratory reaction to moderate activity in boys 11-13 years old.", "content": "Development of the relationship between aerobic capacity and the circulatory and respiratory reaction to moderate activity in boys 11-13 years old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223481"} {"pmid": "4223482", "title": "Capacitance plethysmography of the nasal mucous membrane in man.", "content": "Capacitance plethysmography of the nasal mucous membrane in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223482"} {"pmid": "4223483", "title": "The breakdown of L-leucyl-p-nitroanilide by serum and tissue homogenates.", "content": "The breakdown of L-leucyl-p-nitroanilide by serum and tissue homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223483"} {"pmid": "4223484", "title": "Osmotic resistance of leucocytes of some laboratory animals.", "content": "Osmotic resistance of leucocytes of some laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223484"} {"pmid": "4223485", "title": "A comparison of the practical applicability of two methods used for the evaluation of the hypoxic reaction: factor analysis, multidimensional regression analysis.", "content": "A comparison of the practical applicability of two methods used for the evaluation of the hypoxic reaction: factor analysis, multidimensional regression analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223485"} {"pmid": "4223486", "title": "The safety of physically disabled drivers.", "content": "The safety of physically disabled drivers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223486"} {"pmid": "4223487", "title": "Syngens of Paramecium aurelia in some regions of Moscow and Leningrad.", "content": "Syngens of Paramecium aurelia in some regions of Moscow and Leningrad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223487"} {"pmid": "4223488", "title": "Synergism in recalcitrant acne vulgaris. A report of good results in 78 percent of patients who had failed to respond to other therapy methods.", "content": "Synergism in recalcitrant acne vulgaris. A report of good results in 78 percent of patients who had failed to respond to other therapy methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223488"} {"pmid": "4223489", "title": "The future role of local health authorities in the day care of the young child.", "content": "The future role of local health authorities in the day care of the young child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223489"} {"pmid": "4223491", "title": "Role of the medical social worker in patient disposition.", "content": "Role of the medical social worker in patient disposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223491"} {"pmid": "4223492", "title": "Physical therapy and rehabilitation procedures related to industry.", "content": "Physical therapy and rehabilitation procedures related to industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223492"} {"pmid": "4223493", "title": "Occupational therapy and pre-vocational testing.", "content": "Occupational therapy and pre-vocational testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223493"} {"pmid": "4223494", "title": "Management's role in the utilization of the disabled.", "content": "Management's role in the utilization of the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223494"} {"pmid": "4223495", "title": "Diagnosis and disability evaluations including special measurements.", "content": "Diagnosis and disability evaluations including special measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223495"} {"pmid": "4223499", "title": "Differential staining of acid glycosaminoglycans (mucopolysaccharides) by alcian blue in salt solutions.", "content": "Differential staining of acid glycosaminoglycans (mucopolysaccharides) by alcian blue in salt solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223499"} {"pmid": "4223500", "title": "A new ion association-fractionation technique for identifying individual mucopolysaccharides and other polyanions in tissue sections.", "content": "A new ion association-fractionation technique for identifying individual mucopolysaccharides and other polyanions in tissue sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223500"} {"pmid": "4223501", "title": "An assessment of work opportunities for the handicapped in the philippines.", "content": "An assessment of work opportunities for the handicapped in the philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223501"} {"pmid": "4223509", "title": "Distribution of glycosaminoglycans, hydroxyproline and calcium in healing fractures.", "content": "Distribution of glycosaminoglycans, hydroxyproline and calcium in healing fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223509"} {"pmid": "4223510", "title": "Fibrinolytic and proteolytic activity in acute and chronic leukemia.", "content": "Fibrinolytic and proteolytic activity in acute and chronic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223510"} {"pmid": "4223512", "title": "Histochemical study of acid mucopolysaccharides in the oviduct gland of Cynips folii.", "content": "Histochemical study of acid mucopolysaccharides in the oviduct gland of Cynips folii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223512"} {"pmid": "4223513", "title": "Histochemistry of parablastomatous connective tissue.", "content": "Histochemistry of parablastomatous connective tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223513"} {"pmid": "4223514", "title": "Intracellular glycogen and other polysaccharides in human epidermal tumours.", "content": "Intracellular glycogen and other polysaccharides in human epidermal tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223514"} {"pmid": "4223515", "title": "The prevalence of handicapping conditions in childhood.", "content": "The prevalence of handicapping conditions in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223515"} {"pmid": "4223517", "title": "Clinico-hemodynamic correlations in ventricular septal defect in childhood.", "content": "Clinico-hemodynamic correlations in ventricular septal defect in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223517"} {"pmid": "4223518", "title": "Effect of L-histidine on hepatic histidine ammonia-lyase & histidine-pyruvate aminotransferase levels in rats.", "content": "Effect of L-histidine on hepatic histidine ammonia-lyase & histidine-pyruvate aminotransferase levels in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223518"} {"pmid": "4223519", "title": "Occurrence of L-amino: 2-glyoxylate aminotransferase in lower plants.", "content": "Occurrence of L-amino: 2-glyoxylate aminotransferase in lower plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223519"} {"pmid": "4223520", "title": "Deamination of amino acids by Azotobacter chroococcum.", "content": "Deamination of amino acids by Azotobacter chroococcum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223520"} {"pmid": "4223521", "title": "Enzymatic preparation of (--) & (+) isomers of citramalic acid.", "content": "Enzymatic preparation of (--) & (+) isomers of citramalic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223521"} {"pmid": "4223522", "title": "Synthesis of phospholipid in the blood of patients with essential hypertension.", "content": "Synthesis of phospholipid in the blood of patients with essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223522"} {"pmid": "4223523", "title": "Activities of some enzymes of pentose phosphate pathway of malignant cervix uteri during various stages of malignant growth.", "content": "Activities of some enzymes of pentose phosphate pathway of malignant cervix uteri during various stages of malignant growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223523"} {"pmid": "4223524", "title": "Synthesis of an unstable functional ribonucleic acid in germinating wheat.", "content": "Synthesis of an unstable functional ribonucleic acid in germinating wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223524"} {"pmid": "4223525", "title": "Studies on horse antibodies. I. Development of antibody in different fractions of serum during immunization of horse with diphtheria toxoid.", "content": "Studies on horse antibodies. I. Development of antibody in different fractions of serum during immunization of horse with diphtheria toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223525"} {"pmid": "4223526", "title": "Studies on experimental protein malnutriton. I. Effect of threonine deficiency on glucose-6-phosphate metabolizing enzymes of rat liver.", "content": "Studies on experimental protein malnutriton. I. Effect of threonine deficiency on glucose-6-phosphate metabolizing enzymes of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223526"} {"pmid": "4223527", "title": "Incorporation of glycine-1-14C into tissues & adult rats after protein depletion & repletion.", "content": "Incorporation of glycine-1-14C into tissues & adult rats after protein depletion & repletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223527"} {"pmid": "4223528", "title": "Availability of nicotinic acid in jowar (Sorghum vulgare).", "content": "Availability of nicotinic acid in jowar (Sorghum vulgare).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223528"} {"pmid": "4223529", "title": "Interdependence of dietary protein & vitamins in metabolism. II. Interdependence of vitamin A, ascorbic acid & protein in metabolism.", "content": "Interdependence of dietary protein & vitamins in metabolism. II. Interdependence of vitamin A, ascorbic acid & protein in metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223529"} {"pmid": "4223530", "title": "Role of vitamin A in sulphate metabolism: 3--Sulphate activation in hypervitaminotic A rats.", "content": "Role of vitamin A in sulphate metabolism: 3--Sulphate activation in hypervitaminotic A rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223530"} {"pmid": "4223531", "title": "Purification of ox brain acetylcholinesterase.", "content": "Purification of ox brain acetylcholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223531"} {"pmid": "4223532", "title": "Regulation of arginine biosynthesis in Vibrio cholerae.", "content": "Regulation of arginine biosynthesis in Vibrio cholerae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223532"} {"pmid": "4223533", "title": "Neurotoxic properties of N-substituted oxamic acids.", "content": "Neurotoxic properties of N-substituted oxamic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223533"} {"pmid": "4223534", "title": "Metabolism of coumarin derivatives: a note on the urinary metabolites of calophyllolide, 4-phenylumbelliferone & 4-phenyl-7-methylumbelliferone.", "content": "Metabolism of coumarin derivatives: a note on the urinary metabolites of calophyllolide, 4-phenylumbelliferone & 4-phenyl-7-methylumbelliferone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223534"} {"pmid": "4223535", "title": "Purification & physical properties of a goat intestinal esterase.", "content": "Purification & physical properties of a goat intestinal esterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223535"} {"pmid": "4223536", "title": "Chronic respiratory diseases--a mushrooming challenge.", "content": "Chronic respiratory diseases--a mushrooming challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223536"} {"pmid": "4223538", "title": "Change of philosophy.", "content": "Change of philosophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223538"} {"pmid": "4223539", "title": "Dermatologic cosmetic surgery.", "content": "Dermatologic cosmetic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223539"} {"pmid": "4223537", "title": "Desiccated thyroid U.S.P. or sodium L-thyroxine?", "content": "Desiccated thyroid U.S.P. or sodium L-thyroxine?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223537"} {"pmid": "4223540", "title": "Recent developments in hair preparations.", "content": "Recent developments in hair preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223540"} {"pmid": "4223541", "title": "Evaluation of dermatologic creams containing female hormones.", "content": "Evaluation of dermatologic creams containing female hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223541"} {"pmid": "4223542", "title": "A census of women physicians in the Washington, D.C. Metropolitan area.", "content": "A census of women physicians in the Washington, D.C. Metropolitan area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223542"} {"pmid": "4223543", "title": "My mother, the Doctor. Another solution to a much-discussed problem.", "content": "My mother, the Doctor. Another solution to a much-discussed problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223543"} {"pmid": "4223544", "title": "Studies on heart phosphofructokinase. Purification, crystallization, and properties of sheep heart phosphofructokinase.", "content": "Studies on heart phosphofructokinase. Purification, crystallization, and properties of sheep heart phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223544"} {"pmid": "4223545", "title": "Purification and properties of a tropomyosin-containing protein fraction that sensitizes reconstituted actomyosin to calcium-binding agents.", "content": "Purification and properties of a tropomyosin-containing protein fraction that sensitizes reconstituted actomyosin to calcium-binding agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223545"} {"pmid": "4223546", "title": "Low back pain.", "content": "Low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223546"} {"pmid": "4223547", "title": "Familial mongolism by a G--G mosaic carrier.", "content": "Familial mongolism by a G--G mosaic carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223547"} {"pmid": "4223548", "title": "Diagnosis and conservative treatment of ordinary low back pain.", "content": "Diagnosis and conservative treatment of ordinary low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223548"} {"pmid": "4223551", "title": "Huntington's chorea, dysphagia and death.", "content": "Huntington's chorea, dysphagia and death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223551"} {"pmid": "4223552", "title": "The incidence of osteoporosis in normal women: its relation to age and the menopause.", "content": "The incidence of osteoporosis in normal women: its relation to age and the menopause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223552"} {"pmid": "4223553", "title": "An attempt for direct phage typing of pathogenic staphylococci.", "content": "An attempt for direct phage typing of pathogenic staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223553"} {"pmid": "4223554", "title": "Medical self-help and nutrition courses in Central America.", "content": "Medical self-help and nutrition courses in Central America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223554"} {"pmid": "4223555", "title": "New drugs: the AMA and FDA roles.", "content": "New drugs: the AMA and FDA roles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223555"} {"pmid": "4223556", "title": "Hearing aids for hard of hearing patients.", "content": "Hearing aids for hard of hearing patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223556"} {"pmid": "4223557", "title": "Extraovular saline-induced abortion.", "content": "Extraovular saline-induced abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223557"} {"pmid": "4223560", "title": "Studies on the role of prophylactic desensitization in experimental myocarditis.", "content": "Studies on the role of prophylactic desensitization in experimental myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223560"} {"pmid": "4223567", "title": "[On the problem of obtaining precipitating polio antigens].", "content": "[On the problem of obtaining precipitating polio antigens].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223567"} {"pmid": "4223577", "title": "Separation of adenosine diphosphate--adenosine triphosphate-exchange activity from the cerebral microsomal sodium-plus-potassium ion-stimulated adenosine triphosphatase.", "content": "Separation of adenosine diphosphate--adenosine triphosphate-exchange activity from the cerebral microsomal sodium-plus-potassium ion-stimulated adenosine triphosphatase. 1. A microsomal fraction from ox cerebral cortex catalysed [(14)C]ADP-ATP exchange at a speed similar to that at which it liberated P(i) from ATP in the presence of Na(+), K(+) and Mg(2+). 2. Repeated washing the fraction with MgATP solutions solubilized most of the exchange activity and left the adenosine triphosphatase insoluble and little changed in activity. The exchange activity was accompanied by negligible adenosine-triphosphatase activity and was enriched by precipitation at chosen pH and by DEAE-Sephadex. At no stage was its activity affected by Na(+), K(+) or ouabain. 3. The washed microsomal fraction was exposed to a variety of reagents; a sodium iodide-cysteine treatment increased both adenosine-triphosphatase and exchange activities, as also did a synthetic zeolite. Preparations were obtained with exchange activities less than 3% of their Na(+)-plus-K(+)-stimulated adenosine-triphosphatase activity. Some contribution to the residual exchange activity was made by an adenylate kinase. 4. Thus over 95% of the microsomal ADP-ATP-exchange activity does not take part in the Na(+)-plus-K(+)-stimulated adenosine-triphosphatase reaction. Participation of some of the residual 3% of the ADP-ATP-exchange activity has not been excluded, but there appears no firm evidence for its participation in the adenosine triphosphatase; the bearing of this conclusion on mechanisms proposed for the Na(+)-plus-K(+)-stimulated adenosine triphosphatase is indicated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223577"} {"pmid": "4223580", "title": "An outbreak of infection due to Staphylococcus aureus phage type 80/81 in a veterinary school.", "content": "An outbreak of infection due to Staphylococcus aureus phage type 80/81 in a veterinary school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223580"} {"pmid": "4223583", "title": "The reversible activation of mitochondrial ATPase by high pH.", "content": "The reversible activation of mitochondrial ATPase by high pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223583"} {"pmid": "4223582", "title": "Fibrinolysin studies in hemophilia.", "content": "Fibrinolysin studies in hemophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223582"} {"pmid": "4223585", "title": "Lumbar facet fractures following disk surgery.", "content": "Lumbar facet fractures following disk surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223585"} {"pmid": "4223578", "title": "Evaluation of the 2-minute sit-up test as a measure of muscular endurance and strength.", "content": "Evaluation of the 2-minute sit-up test as a measure of muscular endurance and strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223578"} {"pmid": "4223586", "title": "Ultrastructure of the placenta in hypertensive states. The localization of enzmes hydrolysing adenosine triphosphate in placentae from normal and toxaemic pregnancies.", "content": "Ultrastructure of the placenta in hypertensive states. The localization of enzmes hydrolysing adenosine triphosphate in placentae from normal and toxaemic pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223586"} {"pmid": "4223590", "title": "Children's dentistry--a challenge.", "content": "Children's dentistry--a challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223590"} {"pmid": "4223591", "title": "Existence of an apparent metabolic block in human granulation tissue.", "content": "Existence of an apparent metabolic block in human granulation tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223591"} {"pmid": "4223594", "title": "Advance notice of dental surgery promotes good psychological responses.", "content": "Advance notice of dental surgery promotes good psychological responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223594"} {"pmid": "4223595", "title": "A controlled trial of benzoyl peroxide and precipitated sulfur cream in acne vulgaris.", "content": "A controlled trial of benzoyl peroxide and precipitated sulfur cream in acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223595"} {"pmid": "4223596", "title": "Low back pain in men receiving workmen's compensation.", "content": "Low back pain in men receiving workmen's compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223596"} {"pmid": "4223597", "title": "Abnormal patterns of growth and development in mongolism. An anthropometric study.", "content": "Abnormal patterns of growth and development in mongolism. An anthropometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223597"} {"pmid": "4223598", "title": "Some aspects of the bacteriology of acne vulgaris.", "content": "Some aspects of the bacteriology of acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223598"} {"pmid": "4223606", "title": "Home care program for the chronically ill and the aged of the west regional district, Mayaguez, Puerto Rico.", "content": "Home care program for the chronically ill and the aged of the west regional district, Mayaguez, Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223606"} {"pmid": "4223607", "title": "Adenocarcinoma of the cervix uteri. Review of cases at the Dr. I. Gonzalez Martinez Oncologic Hospital.", "content": "Adenocarcinoma of the cervix uteri. Review of cases at the Dr. I. Gonzalez Martinez Oncologic Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223607"} {"pmid": "4223609", "title": "Hospital practice in Appalachia; report on the Albert Schweitzer Memorial Hospital, Balsam Grove, North Carolina.", "content": "Hospital practice in Appalachia; report on the Albert Schweitzer Memorial Hospital, Balsam Grove, North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223609"} {"pmid": "4223608", "title": "Diffuse glycogenosis.", "content": "Diffuse glycogenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223608"} {"pmid": "4223611", "title": "Air pollution and the lung.", "content": "Air pollution and the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223611"} {"pmid": "4223610", "title": "Air pollution and the heart.", "content": "Air pollution and the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223610"} {"pmid": "4223612", "title": "Four of us: sketches of the four women ophthalmologists of the Massachusetts Eye and Ear Infirmary.", "content": "Four of us: sketches of the four women ophthalmologists of the Massachusetts Eye and Ear Infirmary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223612"} {"pmid": "4223614", "title": "An immunofluorescent study on anti-synovial tissue antibody in the body fluid from patients with rheumatoid arthritis.", "content": "An immunofluorescent study on anti-synovial tissue antibody in the body fluid from patients with rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223614"} {"pmid": "4223615", "title": "Cellular antibody in mice bearing Ehrlich cancer. 3. Relationship of cellular antibody to serum antibody.", "content": "Cellular antibody in mice bearing Ehrlich cancer. 3. Relationship of cellular antibody to serum antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223615"} {"pmid": "4223616", "title": "Fine structure of negatively stained adenovirus type 12.", "content": "Fine structure of negatively stained adenovirus type 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223616"} {"pmid": "4223617", "title": "The relationship between histochemical enzyme activities of brain tumors and clinical features of the patients.", "content": "The relationship between histochemical enzyme activities of brain tumors and clinical features of the patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223617"} {"pmid": "4223618", "title": "Studies on the function of reticulo-endothelial system. II. Effects of the R.E.S. blocking with macro-molecular PVP on the lymphoid cell reproduction and the production of serum antibody.", "content": "Studies on the function of reticulo-endothelial system. II. Effects of the R.E.S. blocking with macro-molecular PVP on the lymphoid cell reproduction and the production of serum antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223618"} {"pmid": "4223619", "title": "Morphological and functional changes in isolated chloroplasts under the influence of oleate.", "content": "Morphological and functional changes in isolated chloroplasts under the influence of oleate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223619"} {"pmid": "4223620", "title": "Reducing failure in vocational rehabilitation.", "content": "Reducing failure in vocational rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223620"} {"pmid": "4223621", "title": "Ocular dracunculosis.", "content": "Ocular dracunculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223621"} {"pmid": "4223622", "title": "Enzymatic adaptation: molecular basis for cardiac glycoside action? 1. Increase in rat heart actomyosin and mitochondrial ATPase specific activities following digoxin injection.", "content": "Enzymatic adaptation: molecular basis for cardiac glycoside action? 1. Increase in rat heart actomyosin and mitochondrial ATPase specific activities following digoxin injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223622"} {"pmid": "4223625", "title": "Muscle spindle activity in dystonic and spastic monkeys.", "content": "Muscle spindle activity in dystonic and spastic monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223625"} {"pmid": "4223626", "title": "Cordotomy for intractable pain of nonmalignant origin. Review of twenty cases.", "content": "Cordotomy for intractable pain of nonmalignant origin. Review of twenty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223626"} {"pmid": "4223629", "title": "Neonatal congestive heart failure as the presenting symptom of cerebral arteriovenous malformation.", "content": "Neonatal congestive heart failure as the presenting symptom of cerebral arteriovenous malformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223629"} {"pmid": "4223631", "title": "Serum mucopolysaccharides in alloxan and steroid diabetes.", "content": "Serum mucopolysaccharides in alloxan and steroid diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223631"} {"pmid": "4223632", "title": "The liver in lipidosis. An electron miscroscopic and histochemical study.", "content": "The liver in lipidosis. An electron miscroscopic and histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223632"} {"pmid": "4223633", "title": "Hyperuricemia with self-mutilation and choreo-athetosis. Lesch-Nyhan syndrome.", "content": "Hyperuricemia with self-mutilation and choreo-athetosis. Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223633"} {"pmid": "4223634", "title": "Effects of cystamine and cysteamine on the adenosine-triphosphatase activity and oxidative phosphorylation of rat-liver mitochondria.", "content": "Effects of cystamine and cysteamine on the adenosine-triphosphatase activity and oxidative phosphorylation of rat-liver mitochondria. 1. Cystamine (2,2'-diaminodiethyl disulphide) caused an unmasking of mitochondrial adenosine triphosphatase and a leakage of Mg(2+) from the mitochondria, and decreased the stimulation of adenosine triphosphatase by 2,4-dinitrophenol. When Mg(2+) was added, cystamine potentiated the activation of adenosine triphosphatase by 2,4-dinitrophenol. 2. Cystamine was without effect on the adenosine triphosphatase of disrupted mitochondria. 3. Cystamine was moderately potent as an uncoupling agent and as an inhibitor of the [(32)P]P(i)-ATP exchange reaction. 4. Cysteamine (2-aminoethanethiol) was without the above effects, when special precautions were taken to counteract its autoxidation. 5. The effects of cystamine should probably be ascribed to its disulphide group, since the diamine cadaverine protected slightly against the loss of Mg(2+) and the decrease of 2,4-dinitrophenol-stimulated adenosine-triphosphatase activity caused by aging of the mitochondria. It is suggested that cystamine acts by a breakdown of mitochondrial permeability barriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223634"} {"pmid": "4223635", "title": "The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster.", "content": "The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223635"} {"pmid": "4223636", "title": "Cardiac myofibrillar ATPase activity in hypophysectomized or thyroidectomized rats.", "content": "Cardiac myofibrillar ATPase activity in hypophysectomized or thyroidectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223636"} {"pmid": "4223638", "title": "Report on a laminar flow surgical facility.", "content": "Report on a laminar flow surgical facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223638"} {"pmid": "4223637", "title": "Controlling static in the clean room.", "content": "Controlling static in the clean room.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223637"} {"pmid": "4223639", "title": "Kinetic evidence for multiple binding sites on phosphofructokinase.", "content": "Kinetic evidence for multiple binding sites on phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223639"} {"pmid": "4223640", "title": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. 8. Properties of a factor conferring oligomycin sensitivity on mitochondrial adenosine triphosphatase.", "content": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. 8. Properties of a factor conferring oligomycin sensitivity on mitochondrial adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223640"} {"pmid": "4223641", "title": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. IX. Reconstruction of oligomycin-sensitive adenosine triphosphatase.", "content": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. IX. Reconstruction of oligomycin-sensitive adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223641"} {"pmid": "4223642", "title": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. X. Correlation of morphology and function in submitochondrial particles.", "content": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. X. Correlation of morphology and function in submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223642"} {"pmid": "4223647", "title": "Eight backward pupils and i.t.a.", "content": "Eight backward pupils and i.t.a.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223647"} {"pmid": "4223648", "title": "Number work at Craig-y-Parc.", "content": "Number work at Craig-y-Parc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223648"} {"pmid": "4223649", "title": "A time for fresh evaluation.", "content": "A time for fresh evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223649"} {"pmid": "4223650", "title": "An outlet after school.", "content": "An outlet after school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223650"} {"pmid": "4223653", "title": "Use of ultrasound in the diagnosis of pericardial effusion.", "content": "Use of ultrasound in the diagnosis of pericardial effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223653"} {"pmid": "4223656", "title": "Clinico-pathological conference.", "content": "Clinico-pathological conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223656"} {"pmid": "4223657", "title": "Derivatives of 2-azabicyclo[2.2.2]octane. II.", "content": "Derivatives of 2-azabicyclo[2.2.2]octane. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223657"} {"pmid": "4223658", "title": "Down's syndrome with a familial D/D reciprocal translocation and a G/G chromosome.", "content": "Down's syndrome with a familial D/D reciprocal translocation and a G/G chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223658"} {"pmid": "4223661", "title": "The effect of clomiphene on hormone excretion in patients with galactorrhoea.", "content": "The effect of clomiphene on hormone excretion in patients with galactorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223661"} {"pmid": "4223662", "title": "Metabolism of dehydroepiandrosterone and dehydroepiandrosterone sulphate by the human foetus at midpregnancy.", "content": "Metabolism of dehydroepiandrosterone and dehydroepiandrosterone sulphate by the human foetus at midpregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223662"} {"pmid": "4223663", "title": "Distribution of some steroid sulphokinases in foetal human tissues.", "content": "Distribution of some steroid sulphokinases in foetal human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223663"} {"pmid": "4223673", "title": "Studies on Na+-K+-activated adenosine triphosphatase. XVI. Its absence from the cation transport system of Ulva lactuca.", "content": "Studies on Na+-K+-activated adenosine triphosphatase. XVI. Its absence from the cation transport system of Ulva lactuca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223673"} {"pmid": "4223674", "title": "An immunochemical study of human plasminogen and plasmin.", "content": "An immunochemical study of human plasminogen and plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223674"} {"pmid": "4223676", "title": "Mucopolysaccharides in experimental hepatic fibrosis.", "content": "Mucopolysaccharides in experimental hepatic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223676"} {"pmid": "4223682", "title": "Nerve implants in botulinum poisoned mammalian muscle.", "content": "Nerve implants in botulinum poisoned mammalian muscle. 1. In albino rats the botulinum poisoned gastrocnemius muscle was supplied with an accessory motor nerve in order to investigate whether muscle fibres with structurally intact but non-transmitting synapses would accept additional innervation. As a control similar operations were made in unpoisoned rats.2. One to three months after nerve implantation the muscles were examined histologically for the presence of a new end-plate zone. In botulinum treated muscles 1662 +/- 165 (mean +/- S.D.) of new end-plates were found. In the control animals only a few (90 +/- 13) were observed in the immediate vicinity of the implanted nerve trunk.3. Following recovery from the paralysing action of botulinum toxin electrical stimulation of both the implanted and the original motor nerve evoked strong mechanical twitches in the gastrocnemius muscle.4. When the nerves were stimulated simultaneously little or no summation of tension occurred, indicating that presumably many of the muscle fibres with new end-plates also had functionally intact junctions from the original nerve. The presence of two end-plates in a muscle fibre was confirmed in a few experiments on single curarized fibres by intracellular recording of end-plate potentials on stimulation of each nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223682"} {"pmid": "4223683", "title": "Reflex and cerebellar influences on alpha and on 'rhythmic' and 'tonic' gamma activity in the intercostal muscle.", "content": "Reflex and cerebellar influences on alpha and on 'rhythmic' and 'tonic' gamma activity in the intercostal muscle. 1. Efferent intercostal alpha and gamma activity and afferent intercostal muscle spindle activity were studied in decerebrate cats in response to stimulation of the anterior lobe of the cerebellum and to postural and other reflexes.2. Low threshold intercostal responses were elicited from lobuli IV and V of the anterior lobe of the cerebellum.3. The existence of two functionally different types of intercostal gamma neurones has been confirmed. These are the ;rhythmic' or ;specifically respiratory' gamma neurones, and the ;tonic' gamma neurones.4. In response to cerebellar stimulation, facilitatory, inhibitory and diphasic tetanic and post-tetanic effects were obtained from alpha and the two types of gamma fibres in both external and internal intercostal nerve branches.5. Generally both inspiratory and expiratory alpha and gamma activity was facilitated in response to tetanic stimulation at contralateral stimulus sites, and inhibited in response to stimulation of ipsilateral sites.6. ;Rhythmic' gamma activity appeared to be rather closely linked to the respiratory alpha activity but the balance between ;rhythmic' gamma and alpha was often changed in response to cerebellar stimulation, as indicated by the responses of primary muscle spindle afferents.7. The ;tonic' gamma neurones were as a rule more responsive to cerebellar stimulation than were the alpha and ;rhythmic' gamma neurones. Long-lasting post-tetanic effects were much more prominent in the ;tonic' gamma fibres than in the alpha or ;rhythmic' gamma fibres.8. ;Rhythmic' gamma activity was abolished after cervical transections of the cord. ;Tonic' gamma activity remained in the spinal preparations although usually at a different discharge rate.9. ;Tonic' gamma neurones were more responsive than the ;rhythmic' gamma neurones to the proprioceptive gamma reflex elicited by passive movements of the chest wall as well as to other spinal and supraspinal reflexes.10. Both ;dynamic' and ;static' gamma fibres seem to be represented in the group of ;tonic' intercostal gamma neurones.11. The significance of the results are discussed with regard to the following two main points: (a) integration of respiratory and postural functions of the intercostal muscles; (b) cerebellar control of the alpha-gamma balance in active contractions and passive relaxations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223683"} {"pmid": "4223687", "title": "Relapsing polychondritis. Analytical literature review and studies on pathogenesis.", "content": "Relapsing polychondritis. Analytical literature review and studies on pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223687"} {"pmid": "4223688", "title": "Radiocarbon cholesterol turnover in cholesterol pericarditis.", "content": "Radiocarbon cholesterol turnover in cholesterol pericarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223688"} {"pmid": "4223691", "title": "Mitochondrial membrane ghosts produced by lipid peroxidation induced by ferrous ion. II. Composition and enzymatic activity.", "content": "Mitochondrial membrane ghosts produced by lipid peroxidation induced by ferrous ion. II. Composition and enzymatic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223691"} {"pmid": "4223693", "title": "Interactions of epsilon-aminocaproic acid with the thrombin clotting and fibrinolytic systems.", "content": "Interactions of epsilon-aminocaproic acid with the thrombin clotting and fibrinolytic systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223693"} {"pmid": "4223696", "title": "Huntington's chorea. A multidisciplinary study of affected parents and first generation offspring.", "content": "Huntington's chorea. A multidisciplinary study of affected parents and first generation offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223696"} {"pmid": "4223697", "title": "A study of the oral toxicity of calcium chloride in dairy cows.", "content": "A study of the oral toxicity of calcium chloride in dairy cows. The effects of oral administration of calcium chloride solutions to dairy cows were studied. When a 0.3 per cent solution was given ad libitum, and as the sole source of water for a period of 75 days, we observed no significant changes in feed consumption, body weight or milk production. The average daily water intake was increased by approximately 20 per cent, and signs of slight gastro-intestinal irritation were seen. No major changes in blood hemoglobin levels, hematocrits, total and differential white cell counts or thrombocyte numbers could be attributed to the treatment. We observed no significant effect on the serum calcium, chloride, magnesium, potassium, or sodium content. The level of inorganic phosphate in the serum rose to higher, but still normal values. During the entire experiment the urine pH was abnormally acid for dairy cows. Electrocardiograms were taken after 45 days of calcium chloride administration, and they appeared normal. When 0.1 and 0.2 per cent solutions were given as the sole source of water for a period of 81 days, the cows remained in good condition, and we observed no changes in appetite, body weight or milk production. In general, dairy cows will refuse to drink calcium chloride solutions when the concentration exceeds 0.5 per cent, even when they have been deprived of water for 18-24 hours. On the other hand, since the administration of lower concentrations for periods of 75 and 81 days did not cause any clinical sign of disease, it seems that on farms where more than one source of water are usually available, poisoning of dairy cattle by calcium chloride in solution is quite unlikely.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223697"} {"pmid": "4223698", "title": "Comparative pathologic and hematologic effects in various species fed cholesterol and fats.", "content": "Comparative pathologic and hematologic effects in various species fed cholesterol and fats. The hematologic response in various animal species fed cholesterol and fat differed with the species and sex. Male rabbits, chickens and guinea pigs could not adequately comensate for the demand for increased red cell production and developed anemia. Female guinea pigs given added cholesterol and fat maintained adequate blood cell production but may have become anemic if the test period had been extended. Bone marrow production was increased in male rats and was sufficient to compensate for red cell loss. Blood and bone marrow values were not altered in female chickens by the dietary treatment. Fatty changes in the liver were common to all species fed added cholesterol and fat but gastric lesions were seen only in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223698"} {"pmid": "4223699", "title": "The formation of plaques by African horse sickness viruses and factors affecting plaque size.", "content": "The formation of plaques by African horse sickness viruses and factors affecting plaque size. Under agar overlay, large and small plaques were observed for African Horse Sickness viruses. The purification of large plaques by cloning was possible. By addition of protamine sulfate to the agar overlay only large plaques were produced. The plaque size variation can not be a suitable marker for determination of variants of this virus since under methyl cellulose and starch gel overlays homogenous plaques were noticed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223699"} {"pmid": "4223700", "title": "Canada's oldest veterinary practice.", "content": "Canada's oldest veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223700"} {"pmid": "4223701", "title": "Genetic counseling and Down's syndrome.", "content": "Genetic counseling and Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223701"} {"pmid": "4223703", "title": "Use of carisoprodol preparations in the management of the lumbosacral syndrome.", "content": "Use of carisoprodol preparations in the management of the lumbosacral syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223703"} {"pmid": "4223706", "title": "Induced tolerance in turkeys to aflatoxin poisoning.", "content": "Induced tolerance in turkeys to aflatoxin poisoning. The consumption of moderately poisonous levels of toxic groundnut meal by turkey poults induced a degree of tolerance to aflatoxin Poults thus ;conditioned' gained more than ;unconditioned' birds on successively higher levels of aflatoxin and were enabled to survive and gain on rations which killed mature turkeys. Ingestion of aflatoxin led to marked alterations in the serum electrophoretic patterns followed in a few weeks by a return to nearly normal patterns. Subsequent increases in aflatoxin intake induced only minimal alternations in the serum patterns but the tolerance appeared unrelated to the hepatotoxic effect because extensive pathological changes developed in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223706"} {"pmid": "4223707", "title": "A note on some helminths of Manitoba chickens.", "content": "A note on some helminths of Manitoba chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223707"} {"pmid": "4223708", "title": "Dimethyl sulfoxide (DMSO).", "content": "Dimethyl sulfoxide (DMSO).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223708"} {"pmid": "4223709", "title": "Exudative epidermitis in pigs. Clinical studies and preliminary transmission trials.", "content": "Exudative epidermitis in pigs. Clinical studies and preliminary transmission trials. Four outbreaks of an infectious, exudative skin disease of 6 to 10 week-old weaned pigs, are described. The disease was seen in fattening barns where weanlings from several sources were mixed. The disease was characterized in the peracute form by the formation, over the entire body, of a brown, greasy, odorous exudate, by loosening of the hoofs, by severe depression, dehydration and death in 3 to 5 days. In the acute form the lesions were identical, but their evolution slower, the mortality was high, and survivors severely stunted. Secondary infections seemed largely responsible for mortality in the acute form. Subacute infections were frequent and characterized by the formation of few to many circular exudative foci which became dry and cleared up completely in about 2 weeks. Antibiotics and mineral supplements were of no value in controlling or preventing the development of lesions or mortality.Minimal-disease pigs were exposed to diseased pigs from 3 of the 4 outbreaks studied and in all cases they developed typical lesions and could transmit the infection to other pigs. Bacteriological examination of field and experimentally produced cases gave inconclusive results pending further study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223709"} {"pmid": "4223712", "title": "The chemical dimensions of a healing incision.", "content": "The chemical dimensions of a healing incision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223712"} {"pmid": "4223715", "title": "Properties of adenosinetriphosphatase in sub-cellular particles of mouse melanoma.", "content": "Properties of adenosinetriphosphatase in sub-cellular particles of mouse melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223715"} {"pmid": "4223717", "title": "The sea climate influence on some functions of the suprarenal glands.", "content": "The sea climate influence on some functions of the suprarenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223717"} {"pmid": "4223719", "title": "On the antigenic composition of diphtheria toxin and toxoid.", "content": "On the antigenic composition of diphtheria toxin and toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223719"} {"pmid": "4223722", "title": "The late apical systolic murmur. Clinical, hemodynamic and angiographic observations.", "content": "The late apical systolic murmur. Clinical, hemodynamic and angiographic observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223722"} {"pmid": "4223723", "title": "A fatal complication of aortic valve fenestration. Coronary ostial obstruction by an engaged embolus.", "content": "A fatal complication of aortic valve fenestration. Coronary ostial obstruction by an engaged embolus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223723"} {"pmid": "4223724", "title": "The continued management of the handicapped child.", "content": "The continued management of the handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223724"} {"pmid": "4223725", "title": "Androgenic steroid complexes with p-bromophenol.", "content": "Androgenic steroid complexes with p-bromophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223725"} {"pmid": "4223718", "title": "Bangkok patients reject wheelchairs.", "content": "Bangkok patients reject wheelchairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223718"} {"pmid": "4223737", "title": "A lymphocyte-stimulating factor produced in vitro.", "content": "A lymphocyte-stimulating factor produced in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223737"} {"pmid": "4223735", "title": "Mucopolysaccharides of whole human spleens in generalized amyloidosis.", "content": "Mucopolysaccharides of whole human spleens in generalized amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223735"} {"pmid": "4223747", "title": "Inhibition of the effect of repetitive stimulation on spinal motoneurones of the cat by morphine and pethidine.", "content": "Inhibition of the effect of repetitive stimulation on spinal motoneurones of the cat by morphine and pethidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223747"} {"pmid": "4223749", "title": "Autoimmune phenomenon in eczema seborrhoeicum.", "content": "Autoimmune phenomenon in eczema seborrhoeicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223749"} {"pmid": "4223750", "title": "The lifespan of red blood cells in experimental lead poisoning, studied with radioactive chromium 51-Cr.", "content": "The lifespan of red blood cells in experimental lead poisoning, studied with radioactive chromium 51-Cr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223750"} {"pmid": "4223754", "title": "The transmission of hog cholera virus by Trichinella spiralis larvae.", "content": "The transmission of hog cholera virus by Trichinella spiralis larvae. Studies have been carried out to determine (a) the possible role of T. spiralis larvae in the transmission of hog cholera virus and (b) to determine the effect of elevated swine temperature on the viability of trichinae. Trichina larvae from hog cholera infected swine were freed from diaphragmatic tissue by artificial digestion. Washed and disinfected larvae transmitted hog cholera virus while the supernatant digestive fluid did not transmit the virus. Infectivity of the virus was lost when the larvae were transmitted through albino rats before administration to swine. Temperature elevation of the swine did not affect the viability of the trichinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223754"} {"pmid": "4223753", "title": "Hemolytic behavior of staphylococci isolated from cows' milk.", "content": "Hemolytic behavior of staphylococci isolated from cows' milk. Patterns of hemolysis produced by staphylococci isolated from milk were investigated on media prepared with bovine, sheep, horse, and rabbit erythrocytes under a variety of cultural circumstances. Hemolytic patterns were sharper and easier to interpret on erythrocyte agar plates when incubated at 37 degrees C in an atmosphere containing 30% CO(2.) Alpha-hemolysin production was greatly enhanced in this environment and was not detected at times when cultures were grown in air only. This was also true of deltahemolysin but to a lesser extent. Very satisfactory identification of alpha, beta- and delta-hemolysins was obtained by streaking BEA plates with the unknown strains perpendicularly to a strain producing beta-hemolysin and incubating in 30% CO(2.) This procedure avoided use of erythrocytes of different species of origin and use of staphylococcal alpha-antitoxin. Prior action of the beta-hemolysin on bovine cells was found to completely inhibit hemolysis from alpha-hemolysin but the reverse was not true. A strain inhibiting beta-hemolysis in air failed to exhibit its antihemolytic properties for 24 hours when incubated in 30% CO(2.) Patterns of hemolysis within areas subject to multiple hemolysins were found to reflect the nature and relative strength of contributing hemolysins or antihemolysins and could be modified by the time sequence of exposure to certain hemolysins or antihemolysins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223753"} {"pmid": "4223761", "title": "Influence of sex on the antiproteolytic activity of rat serum.", "content": "Influence of sex on the antiproteolytic activity of rat serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223761"} {"pmid": "4223764", "title": "Fractionation of acidic polysaccharides derived from a small group of chondrocytes.", "content": "Fractionation of acidic polysaccharides derived from a small group of chondrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223764"} {"pmid": "4223763", "title": "Partial purification and characterization of sodium- and potassium-dependent adenosine triphosphatase from rat-heart muscle.", "content": "Partial purification and characterization of sodium- and potassium-dependent adenosine triphosphatase from rat-heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223763"} {"pmid": "4223765", "title": "Unknown properties of the products of plasmin-degradation of fibrinogen and fibrin.", "content": "Unknown properties of the products of plasmin-degradation of fibrinogen and fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223765"} {"pmid": "4223766", "title": "Occupational therapy in the field of physical disabilities.", "content": "Occupational therapy in the field of physical disabilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223766"} {"pmid": "4223768", "title": "Guidelines for a bioclean spacecraft assembly area.", "content": "Guidelines for a bioclean spacecraft assembly area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223768"} {"pmid": "4223767", "title": "Automation can be an assistive device.", "content": "Automation can be an assistive device.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223767"} {"pmid": "4223762", "title": "Muscle spindles.", "content": "Muscle spindles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223762"} {"pmid": "4223779", "title": "Inhibition of fibrinolytic and thromboplastic activity by Trasylol.", "content": "Inhibition of fibrinolytic and thromboplastic activity by Trasylol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223779"} {"pmid": "4223783", "title": "Studies of staphylococcal infections. II. The role of bacteriophage type, antibiotic resistance, coagulase, and other exotoxins in infections in embryonated eggs.", "content": "Studies of staphylococcal infections. II. The role of bacteriophage type, antibiotic resistance, coagulase, and other exotoxins in infections in embryonated eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223783"} {"pmid": "4223785", "title": "Changes in psychologic test (WAIS) scores of older disabled persons during a vocational rehabilitation program.", "content": "Changes in psychologic test (WAIS) scores of older disabled persons during a vocational rehabilitation program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223785"} {"pmid": "4223788", "title": "Relation of increase in muscle mass to performance of hypertrophied right ventricle in the dog.", "content": "Relation of increase in muscle mass to performance of hypertrophied right ventricle in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223788"} {"pmid": "4223778", "title": "A Vermont program helps disabled rural homemakers.", "content": "A Vermont program helps disabled rural homemakers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223778"} {"pmid": "4223789", "title": "Cardiac myosin adenosinetriphosphatase activity. Modifying factors and comparison with skeletal muscle myosin adenosinetriphosphatase activity.", "content": "Cardiac myosin adenosinetriphosphatase activity. Modifying factors and comparison with skeletal muscle myosin adenosinetriphosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223789"} {"pmid": "4223790", "title": "Management of acne vulgaris.", "content": "Management of acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223790"} {"pmid": "4223795", "title": "Reproduction in the ferret (Mustela furo). I. Uterine histology and histochemistry during pregnancy and pseudopregnancy.", "content": "Reproduction in the ferret (Mustela furo). I. Uterine histology and histochemistry during pregnancy and pseudopregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223795"} {"pmid": "4223803", "title": "Identification of 3-beta, 17-beta-dihydroxyandrost-5-ene, 3-beta, 20-alpha-dihydroxypregn-5-ene and epiandrosterone in human peripheral blood.", "content": "Identification of 3-beta, 17-beta-dihydroxyandrost-5-ene, 3-beta, 20-alpha-dihydroxypregn-5-ene and epiandrosterone in human peripheral blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223803"} {"pmid": "4223804", "title": "Metabolism of 7-3H-dehydroisoandrosterone in patients with virilizing adrenal tumors.", "content": "Metabolism of 7-3H-dehydroisoandrosterone in patients with virilizing adrenal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223804"} {"pmid": "4223807", "title": "Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma.", "content": "Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223807"} {"pmid": "4223808", "title": "A handicapped patient's plea: consider the whole person.", "content": "A handicapped patient's plea: consider the whole person.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223808"} {"pmid": "4223809", "title": "Loss of antibiotic resistance in Staphylococcus aureus resulting from growth at high temperature.", "content": "Loss of antibiotic resistance in Staphylococcus aureus resulting from growth at high temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223809"} {"pmid": "4223810", "title": "Some pitfalls in the valuation of cardiac chamber enlargement on chest roentgenograms.", "content": "Some pitfalls in the valuation of cardiac chamber enlargement on chest roentgenograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223810"} {"pmid": "4223811", "title": "Hirschsprung's disease and mongolism.", "content": "Hirschsprung's disease and mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223811"} {"pmid": "4223813", "title": "Congenital aortic sinus aneurysms with particular reference to dissection of the interventricular septum.", "content": "Congenital aortic sinus aneurysms with particular reference to dissection of the interventricular septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223813"} {"pmid": "4223814", "title": "Preoperative and postoperative electrocardiogram in complete transposition of the great vessels.", "content": "Preoperative and postoperative electrocardiogram in complete transposition of the great vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223814"} {"pmid": "4223815", "title": "The temporal sequence of lymph flow in the right lymphatic duct in experimental chronic pulmonary edema.", "content": "The temporal sequence of lymph flow in the right lymphatic duct in experimental chronic pulmonary edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223815"} {"pmid": "4223817", "title": "The challenge of research on mucus.", "content": "The challenge of research on mucus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223817"} {"pmid": "4223816", "title": "Clinical pathologic conference.", "content": "Clinical pathologic conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223816"} {"pmid": "4223818", "title": "Acid mucopolysaccharide composition in human colon.", "content": "Acid mucopolysaccharide composition in human colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223818"} {"pmid": "4223820", "title": "Tritiated thymidine uptake by group G chromosomes of female individuals with Down's syndrome.", "content": "Tritiated thymidine uptake by group G chromosomes of female individuals with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223820"} {"pmid": "4223819", "title": "Serum inhibitors of elastase, trypsin, and plasmin in chronic rheumatic diseases.", "content": "Serum inhibitors of elastase, trypsin, and plasmin in chronic rheumatic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223819"} {"pmid": "4223821", "title": "Fungal infection of the nails.", "content": "Fungal infection of the nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223821"} {"pmid": "4223822", "title": "Cutaneous manifestations of drug toxicity.", "content": "Cutaneous manifestations of drug toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223822"} {"pmid": "4223823", "title": "Effect of biotin on hair roots and sebum excretion in women with diffuse alopecia.", "content": "Effect of biotin on hair roots and sebum excretion in women with diffuse alopecia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223823"} {"pmid": "4223829", "title": "Medical testimony in a workmen's compensation case of hiatal hernia, bilateral vagotomy, pyloroplasty, and tube gastrostomy, showing the cross-examinations of the internists, radiologist, and surgeon called by respondents (defendants).", "content": "Medical testimony in a workmen's compensation case of hiatal hernia, bilateral vagotomy, pyloroplasty, and tube gastrostomy, showing the cross-examinations of the internists, radiologist, and surgeon called by respondents (defendants).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223829"} {"pmid": "4223828", "title": "Industrial aspects of abdominal trauma.", "content": "Industrial aspects of abdominal trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223828"} {"pmid": "4223831", "title": "Coagulation changes during experimental hemorrhagic shock. Clotting activity, contribution of splanchnic circulation and acidosis as controlled by THAM.", "content": "Coagulation changes during experimental hemorrhagic shock. Clotting activity, contribution of splanchnic circulation and acidosis as controlled by THAM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223831"} {"pmid": "4223833", "title": "Laceration of abdominal aorta and study of intact abdominal wall as tamponade: report of survival and literature review.", "content": "Laceration of abdominal aorta and study of intact abdominal wall as tamponade: report of survival and literature review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223833"} {"pmid": "4223832", "title": "Removal of impacted pulmonary emboli by retrograde injection of fibrinolysin into the pulmonary veins. Report of three cases and experimental studies.", "content": "Removal of impacted pulmonary emboli by retrograde injection of fibrinolysin into the pulmonary veins. Report of three cases and experimental studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223832"} {"pmid": "4223865", "title": "The anti-seborrheic qualities of zinc pyrithione (zinc pyridine-2-thiol-1-oxide) in a cream vehicle. 1. A preliminary report.", "content": "The anti-seborrheic qualities of zinc pyrithione (zinc pyridine-2-thiol-1-oxide) in a cream vehicle. 1. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223865"} {"pmid": "4223867", "title": "Water fluoridation--its effect on pedodontics.", "content": "Water fluoridation--its effect on pedodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223867"} {"pmid": "4223869", "title": "Human relations in a pedodontic practice.", "content": "Human relations in a pedodontic practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223869"} {"pmid": "4223874", "title": "Handicapped children in dental practice.", "content": "Handicapped children in dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223874"} {"pmid": "4223878", "title": "Morphological and biochemical correlates of cerebral microsomes. II. A study of the structural association of glutamine synthetase, ATPase, and an esterase acting on o-nitrophenyl acetate.", "content": "Morphological and biochemical correlates of cerebral microsomes. II. A study of the structural association of glutamine synthetase, ATPase, and an esterase acting on o-nitrophenyl acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223878"} {"pmid": "4223871", "title": "Senior dental student recognition awards for 1966.", "content": "Senior dental student recognition awards for 1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223871"} {"pmid": "4223880", "title": "An evaluation of 51 patients with hepatic artery infusion.", "content": "An evaluation of 51 patients with hepatic artery infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223880"} {"pmid": "4223870", "title": "Pain control: trigeminal neuralgia--a review of etiology and treatment.", "content": "Pain control: trigeminal neuralgia--a review of etiology and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223870"} {"pmid": "4223884", "title": "Vascular connective tissue under the influence of oestrogens. I. Biochemical and morphological studies of aortae of untreated female and male rabbits, and aortae of castrated and sham-operated female rabbits.", "content": "Vascular connective tissue under the influence of oestrogens. I. Biochemical and morphological studies of aortae of untreated female and male rabbits, and aortae of castrated and sham-operated female rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223884"} {"pmid": "4223875", "title": "Job readiness: key to placement.", "content": "Job readiness: key to placement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223875"} {"pmid": "4223885", "title": "Myocardosis and cardiac failure in men.", "content": "Myocardosis and cardiac failure in men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223885"} {"pmid": "4223890", "title": "On urinary acid mucopolysaccharides in a case of gargoylism (Hurler's syndrome). A preliminary note.", "content": "On urinary acid mucopolysaccharides in a case of gargoylism (Hurler's syndrome). A preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223890"} {"pmid": "4223889", "title": "Depression of afferent activity originating in muscle spindles induced by mephenesin, procaine and caramiphen.", "content": "Depression of afferent activity originating in muscle spindles induced by mephenesin, procaine and caramiphen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223889"} {"pmid": "4223891", "title": "Studies on acid mucopolysaccharides in urine. 1. On urinary acid mucopolysaccharides from patients with mongolism (Down's syndrome).", "content": "Studies on acid mucopolysaccharides in urine. 1. On urinary acid mucopolysaccharides from patients with mongolism (Down's syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223891"} {"pmid": "4223893", "title": "A probable case of Dracunculus medinensis (Linnaeus, 1758) Gallandant, 1773, in a dog in Pennsylvania.", "content": "A probable case of Dracunculus medinensis (Linnaeus, 1758) Gallandant, 1773, in a dog in Pennsylvania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223893"} {"pmid": "4223907", "title": "Fluoridation's benefits not limited to health: some observations, some predictions.", "content": "Fluoridation's benefits not limited to health: some observations, some predictions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223907"} {"pmid": "4223908", "title": "The preparation of some 4-substituted nicotinic acids and nicotinamides.", "content": "The preparation of some 4-substituted nicotinic acids and nicotinamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223908"} {"pmid": "4223909", "title": "Placental estrogen biosynthesis during human pregnancy.", "content": "Placental estrogen biosynthesis during human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223909"} {"pmid": "4223912", "title": "Virus aetiology for Down's syndrome (mongolism).", "content": "Virus aetiology for Down's syndrome (mongolism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223912"} {"pmid": "4223914", "title": "Diagnosis of retinal detachment.", "content": "Diagnosis of retinal detachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223914"} {"pmid": "4223915", "title": "Management of cervical carcinoma in the elderly patient.", "content": "Management of cervical carcinoma in the elderly patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223915"} {"pmid": "4223916", "title": "Sunlight and skin. 3. Degenerative and neoplastic effects.", "content": "Sunlight and skin. 3. Degenerative and neoplastic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223916"} {"pmid": "4223917", "title": "Electrocardiogram of the month.", "content": "Electrocardiogram of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223917"} {"pmid": "4223894", "title": "Acid mucopolysaccharides and lipids of Japanese arteries, with special reference to the absence of hyaluronic acid in Japanese cerebral artery.", "content": "Acid mucopolysaccharides and lipids of Japanese arteries, with special reference to the absence of hyaluronic acid in Japanese cerebral artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223894"} {"pmid": "4223918", "title": "Hearing measurement and hearing loss.", "content": "Hearing measurement and hearing loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223918"} {"pmid": "4223919", "title": "University of Arkansas Medical Center.", "content": "University of Arkansas Medical Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223919"} {"pmid": "4223920", "title": "Colles' fractures.", "content": "Colles' fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223920"} {"pmid": "4223921", "title": "Acute and chronic intestinal obstruction: the development of current concepts of management.", "content": "Acute and chronic intestinal obstruction: the development of current concepts of management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223921"} {"pmid": "4223913", "title": "Arterial infusion chemotherapy of liver cancer.", "content": "Arterial infusion chemotherapy of liver cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223913"} {"pmid": "4223972", "title": "Dental care for the homebound aged patient.", "content": "Dental care for the homebound aged patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223972"} {"pmid": "4223977", "title": "Vitamin C-induced increase of dermatan sulfate in cultured Hurler's fibroblasts.", "content": "Vitamin C-induced increase of dermatan sulfate in cultured Hurler's fibroblasts. In fibroblasts taken from patients witli Hurler's syndromne and grown in cultlure, dermatan sulfate constituted a larger percentage of the total sulfated glycosaminoglycans than it did in cultured fibroblasts from unaffected individuals. Moreover, the addition of ascorbic acid (vitamnin C) to the culture medium markedly increased the concentration of dermatan sulfate in the Hurler's fibroblasts but not in the normal fibroblasts. The biochemical phenotype of the Hurler's cells persisted during 28 weeks of serial culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223977"} {"pmid": "4223978", "title": "Work and heart disease in Wisconsin. I. Medical basis for workmen's compensation awards over ten years.", "content": "Work and heart disease in Wisconsin. I. Medical basis for workmen's compensation awards over ten years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223978"} {"pmid": "4223979", "title": "Acid mucopolysaccharide and hexosamine metabolism in dermal connective tissue of adrenalectomized rats.", "content": "Acid mucopolysaccharide and hexosamine metabolism in dermal connective tissue of adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223979"} {"pmid": "4223980", "title": "Differences in variability of discharge frequency between primary and secondary muscle spindle afferent endings of the cat.", "content": "Differences in variability of discharge frequency between primary and secondary muscle spindle afferent endings of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223980"} {"pmid": "4223981", "title": "DNA synthesis and differentiation in embryonic kidney mesenchyme in vitro.", "content": "DNA synthesis and differentiation in embryonic kidney mesenchyme in vitro. Mitosis accompanies the differentiation of embryonic metanephrogenic mesenchyme in vitro. Inhibition of mitosis by 5-fluorodeoxyuridine, but not by x-rays, is associated with inhibition of differentiation. The difference may be due to the effect of 5-fluorode-oxyuridine on DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223981"} {"pmid": "4223982", "title": "The effect of restraint on the content of acid polysaccharides of glandular gastric wall in rat.", "content": "The effect of restraint on the content of acid polysaccharides of glandular gastric wall in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223982"} {"pmid": "4223984", "title": "Case records of the Massachusetts General Hospital. Case 40-1966.", "content": "Case records of the Massachusetts General Hospital. Case 40-1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223984"} {"pmid": "4223986", "title": "Combined mongolism and leukemia. Report of eight cases with chromosome studies.", "content": "Combined mongolism and leukemia. Report of eight cases with chromosome studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223986"} {"pmid": "4223987", "title": "Normal-21-trisomy mosaicism. Report of four cases and review of the subject.", "content": "Normal-21-trisomy mosaicism. Report of four cases and review of the subject.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4223987"} {"pmid": "4224029", "title": "Nature and significance of changes in the houseparent role in institutions for children.", "content": "Nature and significance of changes in the houseparent role in institutions for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224029"} {"pmid": "4224049", "title": "Diagnostic significance of atrial fibrillatory waves.", "content": "Diagnostic significance of atrial fibrillatory waves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224049"} {"pmid": "4224051", "title": "Dental problems in children.", "content": "Dental problems in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224051"} {"pmid": "4224050", "title": "The thrombolytic therapy of acute myocardial infarction.", "content": "The thrombolytic therapy of acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224050"} {"pmid": "4224053", "title": "New Zealand's external aid in dental health.", "content": "New Zealand's external aid in dental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224053"} {"pmid": "4224055", "title": "Diagnosis and treatment of low back pain with emphasis on the herniated disc.", "content": "Diagnosis and treatment of low back pain with emphasis on the herniated disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224055"} {"pmid": "4224056", "title": "Mucopolysaccharide from patients with cystic fibrosis of the pancreas.", "content": "Mucopolysaccharide from patients with cystic fibrosis of the pancreas. Physical and immunologic methods were used to demonstrate the presence of an apparently unique glycoprotein in stool and tissue of patients having cystic fibrosis of the pancreas. The detection of a molecular structure specific for the disease is consistent with the apparent hereditary nature of the affection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224056"} {"pmid": "4224059", "title": "Understanding backache, tension and fatigue.", "content": "Understanding backache, tension and fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224059"} {"pmid": "4224061", "title": "Some observations on the caseinolytic properties of a purified, activator-free, porcine plasmin preparation.", "content": "Some observations on the caseinolytic properties of a purified, activator-free, porcine plasmin preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224061"} {"pmid": "4224060", "title": "Reaction of rabbit leucocytes to staphylococcal (Panton-Valentine) leucocidin in vivo.", "content": "Reaction of rabbit leucocytes to staphylococcal (Panton-Valentine) leucocidin in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224060"} {"pmid": "4224062", "title": "The influence of time upon the inhibition of plasmin by normal, human serum.", "content": "The influence of time upon the inhibition of plasmin by normal, human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224062"} {"pmid": "4224063", "title": "Studies on the inhibition of plasmin caseinolysis by human serum and a method for the assay of inhibiting activity.", "content": "Studies on the inhibition of plasmin caseinolysis by human serum and a method for the assay of inhibiting activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224063"} {"pmid": "4224057", "title": "The epidemiology of gingivitis in children.", "content": "The epidemiology of gingivitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224057"} {"pmid": "4224067", "title": "Urinary amino acid excretion in mongolism.", "content": "Urinary amino acid excretion in mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224067"} {"pmid": "4224068", "title": "Studies on glycolysis of red blood cells in anemias. I. Congenital microspherocytosis.", "content": "Studies on glycolysis of red blood cells in anemias. I. Congenital microspherocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224068"} {"pmid": "4224058", "title": "The fibrinolytic enzyme system in cervical mucus.", "content": "The fibrinolytic enzyme system in cervical mucus. A clinical study was undertaken to assess the fibrinolytic enzyme system in cervical mucus in relation to the different stages of the menstrual cycle. Samples of cervical mucus from 8 women in the reproductive stage were taken on different days of the cycle and tested for components of the fibrinolytic system. The testing procedure is explained and the results graphed. Activator was found to disappear from the mucus for 2 days pre- and post-ovulation. Heating and freezing the mucus did not destroy the fibrinolytic activity. Testing was conducted for the presence of such other agents as proactivator, plasmin, and plasminogen in the mucus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224058"} {"pmid": "4224070", "title": "The effect of premedication with chlorpheniramine on reactions to methylglucamine iodipamide.", "content": "The effect of premedication with chlorpheniramine on reactions to methylglucamine iodipamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224070"} {"pmid": "4224071", "title": "Translocation mongolism.", "content": "Translocation mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224071"} {"pmid": "4224072", "title": "Mucopolysaccharide excretion in patients with Hurler's syndrome, their families, and normal man.", "content": "Mucopolysaccharide excretion in patients with Hurler's syndrome, their families, and normal man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224072"} {"pmid": "4224075", "title": "Rosacea and acne.", "content": "Rosacea and acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224075"} {"pmid": "4224074", "title": "Pharmacologic properties of bis-quaternary ammonium derivatives of m- and p- di-(2-aminopropyl)-benzene.", "content": "Pharmacologic properties of bis-quaternary ammonium derivatives of m- and p- di-(2-aminopropyl)-benzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224074"} {"pmid": "4224077", "title": "Histochemical identification of acid mucopolysaccharides in cat lingual glands.", "content": "Histochemical identification of acid mucopolysaccharides in cat lingual glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224077"} {"pmid": "4224076", "title": "On the biosynthesis of testicular steroids in vitro and its inhibition.", "content": "On the biosynthesis of testicular steroids in vitro and its inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224076"} {"pmid": "4224078", "title": "The proteolytic activity of citrated stored blood and some proteins of the clotting system.", "content": "The proteolytic activity of citrated stored blood and some proteins of the clotting system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224078"} {"pmid": "4224079", "title": "A fossil human bone from Anatolia.", "content": "A fossil human bone from Anatolia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224079"} {"pmid": "4224080", "title": "Some factors of human gait.", "content": "Some factors of human gait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224080"} {"pmid": "4224081", "title": "Palmar dermatoglyphics of the Dogon and Peul of Mali.", "content": "Palmar dermatoglyphics of the Dogon and Peul of Mali.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224081"} {"pmid": "4224082", "title": "Nucleic acid synthesis in x-irradiated thymocytes.", "content": "Nucleic acid synthesis in x-irradiated thymocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224082"} {"pmid": "4224083", "title": "Treatment of seborrheic dermatitis in the Negro scalp.", "content": "Treatment of seborrheic dermatitis in the Negro scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224083"} {"pmid": "4224084", "title": "Successful total correction of ventricular septal defect, diverticulum of the left ventricle, and anomaly of the thoracoabdominal wall in an 11-year-old boy with cardiac dextroversion.", "content": "Successful total correction of ventricular septal defect, diverticulum of the left ventricle, and anomaly of the thoracoabdominal wall in an 11-year-old boy with cardiac dextroversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224084"} {"pmid": "4224085", "title": "Bacteriophage typing of Staphylococcus aureus using a single concentration of phage (100 x RTD).", "content": "Bacteriophage typing of Staphylococcus aureus using a single concentration of phage (100 x RTD).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224085"} {"pmid": "4224086", "title": "Physicians, dentists, and children.", "content": "Physicians, dentists, and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224086"} {"pmid": "4224087", "title": "Repression and the control of cyclic enzyme synthesis in Bacillus subtilis.", "content": "Repression and the control of cyclic enzyme synthesis in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224087"} {"pmid": "4224089", "title": "Histoenzymatic reactions in experimental lead poisoning in rabbits.", "content": "Histoenzymatic reactions in experimental lead poisoning in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224089"} {"pmid": "4224092", "title": "Interaction of streptokinase and human plasminogen. 3. Plasmin and activator activities in reaction mixtures of streptokinase and human plasminogen or human plasmin of various molar ratios.", "content": "Interaction of streptokinase and human plasminogen. 3. Plasmin and activator activities in reaction mixtures of streptokinase and human plasminogen or human plasmin of various molar ratios.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224092"} {"pmid": "4224091", "title": "Swelling and shrinkage phenomena in liver mitochondria. V. Permeability of the mitochondrial membrane to univalent cations: effect of Mg++.", "content": "Swelling and shrinkage phenomena in liver mitochondria. V. Permeability of the mitochondrial membrane to univalent cations: effect of Mg++.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224091"} {"pmid": "4224093", "title": "Urokinase levels in urine after nicotinic acid injection.", "content": "Urokinase levels in urine after nicotinic acid injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224093"} {"pmid": "4224094", "title": "Comparison of caseinolytic and fibrinolytic assays for plasmin (fibrinolysin) in \"fibrinolytic agents\".", "content": "Comparison of caseinolytic and fibrinolytic assays for plasmin (fibrinolysin) in \"fibrinolytic agents\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224094"} {"pmid": "4224095", "title": "The fine structure of nuclei as revealed by electron microscopy. 3. Adenosine triphosphatase activity in the pores of nuclear envelope of mouse choroid plexus epithelial cells.", "content": "The fine structure of nuclei as revealed by electron microscopy. 3. Adenosine triphosphatase activity in the pores of nuclear envelope of mouse choroid plexus epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224095"} {"pmid": "4224096", "title": "Electrocardiographic and vectorcardiographic signs of left and right ventricular hypertrophy in endurance athletes.", "content": "Electrocardiographic and vectorcardiographic signs of left and right ventricular hypertrophy in endurance athletes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224096"} {"pmid": "4224106", "title": "Glenrose . . . Canada's unique school-hospital.", "content": "Glenrose . . . Canada's unique school-hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224106"} {"pmid": "4224110", "title": "Presence of sodium-potassium-stimulated ATPase in boar epididymal spermatozoon.", "content": "Presence of sodium-potassium-stimulated ATPase in boar epididymal spermatozoon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224110"} {"pmid": "4224111", "title": "Histochemical demonstration of sodium-potassium-activated adenosinetriphosphatase in normal and leukaemic granulocytes.", "content": "Histochemical demonstration of sodium-potassium-activated adenosinetriphosphatase in normal and leukaemic granulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224111"} {"pmid": "4224112", "title": "Histoenzymatic studies on the behavior of succinic acid dehydrogenase, NADH2 tetrazolium reductase, ATP-ase and alkaline phosphatase in cancer of the uterine cervix in women.", "content": "Histoenzymatic studies on the behavior of succinic acid dehydrogenase, NADH2 tetrazolium reductase, ATP-ase and alkaline phosphatase in cancer of the uterine cervix in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224112"} {"pmid": "4224114", "title": "Arabic historiography as related to the health professions in medieval Islam.", "content": "Arabic historiography as related to the health professions in medieval Islam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224114"} {"pmid": "4224107", "title": "Changes in reactivity of the heart to sympathetic and parasympathetic influences during prolonged compensatory hyperfunction.", "content": "Changes in reactivity of the heart to sympathetic and parasympathetic influences during prolonged compensatory hyperfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224107"} {"pmid": "4224108", "title": "Indices of blood gases compared in healthy persons and heart patients in the Tashkent climate.", "content": "Indices of blood gases compared in healthy persons and heart patients in the Tashkent climate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224108"} {"pmid": "4224120", "title": "The etiology and pathogenesis of pain of spinal origin.", "content": "The etiology and pathogenesis of pain of spinal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224120"} {"pmid": "4224119", "title": "Low back pain etiology and pathogenesis.", "content": "Low back pain etiology and pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224119"} {"pmid": "4224109", "title": "Epidemiologic efficacy of live influenza vaccine during 1962 outbreaks of influenza A2 and B.", "content": "Epidemiologic efficacy of live influenza vaccine during 1962 outbreaks of influenza A2 and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224109"} {"pmid": "4224121", "title": "Emotion and low back pain.", "content": "Emotion and low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224121"} {"pmid": "4224122", "title": "The compensation back.", "content": "The compensation back.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224122"} {"pmid": "4224123", "title": "Management of low back pain--the examination.", "content": "Management of low back pain--the examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224123"} {"pmid": "4224124", "title": "Results in surgical treatment of herniated lumbar intervertebral discs: investigation of the late results in subjects with and without supplementary spinal fusion--a preliminary report.", "content": "Results in surgical treatment of herniated lumbar intervertebral discs: investigation of the late results in subjects with and without supplementary spinal fusion--a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224124"} {"pmid": "4224131", "title": "Macular dystrophy of the cornea. A histochemical and electron microscopic study.", "content": "Macular dystrophy of the cornea. A histochemical and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224131"} {"pmid": "4224132", "title": "Amiphenazole sensitivity with oral ulceration.", "content": "Amiphenazole sensitivity with oral ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224132"} {"pmid": "4224133", "title": "Possible genetic consequences of family planning.", "content": "Possible genetic consequences of family planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224133"} {"pmid": "4224134", "title": "Low back pain.", "content": "Low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224134"} {"pmid": "4224136", "title": "Fungi in nails.", "content": "Fungi in nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224136"} {"pmid": "4224135", "title": "A new type of spatial vectorcardiograph.", "content": "A new type of spatial vectorcardiograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224135"} {"pmid": "4224137", "title": "Management of disorders of the nails.", "content": "Management of disorders of the nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224137"} {"pmid": "4224138", "title": "Glycoprotein and collagen metabolism in the dermis of hypophysectomized rats.", "content": "Glycoprotein and collagen metabolism in the dermis of hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224138"} {"pmid": "4224139", "title": "Hunter-Hurler Syndrome: clinical and biochemical study. Combined clinical staff conference at th National Institutes of Health.", "content": "Hunter-Hurler Syndrome: clinical and biochemical study. Combined clinical staff conference at th National Institutes of Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224139"} {"pmid": "4224143", "title": "Eczematous dermatitis produced by airborne molds.", "content": "Eczematous dermatitis produced by airborne molds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224143"} {"pmid": "4224145", "title": "A genetical study of Hirschsprung's disease; congenital intestinal aganglionosis.", "content": "A genetical study of Hirschsprung's disease; congenital intestinal aganglionosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224145"} {"pmid": "4224144", "title": "Effect of pH on the kinetics of frog muscle phosphofructokinase.", "content": "Effect of pH on the kinetics of frog muscle phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224144"} {"pmid": "4224146", "title": "Pathogenesis of urolithiasis: relation of urinary fibrinolytic activity to nondialyzable urinary solids.", "content": "Pathogenesis of urolithiasis: relation of urinary fibrinolytic activity to nondialyzable urinary solids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224146"} {"pmid": "4224147", "title": "Characterization of fibrinolytic activity of vascular intima.", "content": "Characterization of fibrinolytic activity of vascular intima.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224147"} {"pmid": "4224148", "title": "Control of glycolysis in human erythrocytes by inorganic phosphate and sulfate.", "content": "Control of glycolysis in human erythrocytes by inorganic phosphate and sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224148"} {"pmid": "4224150", "title": "Familial non-progressive myopathy with muscle cramps after exercise. A new disease associated with cores in the muscle fibres.", "content": "Familial non-progressive myopathy with muscle cramps after exercise. A new disease associated with cores in the muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224150"} {"pmid": "4224149", "title": "Effects of acetylcholine infused into renal artery of dogs.", "content": "Effects of acetylcholine infused into renal artery of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224149"} {"pmid": "4224152", "title": "Staphylococcus aureus strains in the \"52, 52A, 80, 81 complex\".", "content": "Staphylococcus aureus strains in the \"52, 52A, 80, 81 complex\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224152"} {"pmid": "4224151", "title": "Formation of estrogens by hydatidiform moles in vitro.", "content": "Formation of estrogens by hydatidiform moles in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224151"} {"pmid": "4224153", "title": "Industrial dermatitis.", "content": "Industrial dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224153"} {"pmid": "4224154", "title": "Legal aspects of accidents.", "content": "Legal aspects of accidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224154"} {"pmid": "4224155", "title": "Thoughts on the accessibility of places of work to disabled employees and clients.", "content": "Thoughts on the accessibility of places of work to disabled employees and clients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224155"} {"pmid": "4224157", "title": "Maternal transmission of a 21/1 translocation associated with Down's syndrome.", "content": "Maternal transmission of a 21/1 translocation associated with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224157"} {"pmid": "4224158", "title": "Urinary tetrahydrocortisone and tetrahydrocortisol in infants born of mothers treated with corticosteroids during pregnancy.", "content": "Urinary tetrahydrocortisone and tetrahydrocortisol in infants born of mothers treated with corticosteroids during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224158"} {"pmid": "4224159", "title": "The renal excretion of ethylenediaminetetraacetate in the dog.", "content": "The renal excretion of ethylenediaminetetraacetate in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224159"} {"pmid": "4224160", "title": "Skin sensitivity to phenindione. Report of a case.", "content": "Skin sensitivity to phenindione. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224160"} {"pmid": "4224163", "title": "Aldosterone and oxidative phosphorylation in liver mitochondria.", "content": "Aldosterone and oxidative phosphorylation in liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224163"} {"pmid": "4224164", "title": "Herpetic whitlow.", "content": "Herpetic whitlow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224164"} {"pmid": "4224165", "title": "Changes in the amount of urinary androgen hormones in students during intensive intellectual work.", "content": "Changes in the amount of urinary androgen hormones in students during intensive intellectual work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224165"} {"pmid": "4224166", "title": "Effect of tetracyclines and chloramphenicol on biosynthesis in vitro. (Immunologic and histochemical studies).", "content": "Effect of tetracyclines and chloramphenicol on biosynthesis in vitro. (Immunologic and histochemical studies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224166"} {"pmid": "4224167", "title": "Ultra-low frequency acceleration ballistocardiogram in experimentally induced myocarditis.", "content": "Ultra-low frequency acceleration ballistocardiogram in experimentally induced myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224167"} {"pmid": "4224168", "title": "Methionine S35 biosynthesis under conditions of different functional strain and varying severity of the streptococcal inflammatory process.", "content": "Methionine S35 biosynthesis under conditions of different functional strain and varying severity of the streptococcal inflammatory process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224168"} {"pmid": "4224169", "title": "Changes in blood glucose level induced by repeated streptococcal infections.", "content": "Changes in blood glucose level induced by repeated streptococcal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224169"} {"pmid": "4224170", "title": "Changes in serum transaminases and lactate-dehydrogenase in experimentally induced myocarditis in dogs.", "content": "Changes in serum transaminases and lactate-dehydrogenase in experimentally induced myocarditis in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224170"} {"pmid": "4224171", "title": "Transaminase activity and destructive-proliferative changes. (Experimental study).", "content": "Transaminase activity and destructive-proliferative changes. (Experimental study).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224171"} {"pmid": "4224172", "title": "Comparative studies of OT and RT23 tuberculin.", "content": "Comparative studies of OT and RT23 tuberculin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224172"} {"pmid": "4224174", "title": "Effect of serotonine on circulation.", "content": "Effect of serotonine on circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224174"} {"pmid": "4224173", "title": "Comparative studies of Monrad and Mantoux tests.", "content": "Comparative studies of Monrad and Mantoux tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224173"} {"pmid": "4224175", "title": "The effect of spinal injury on employment in a heavy industry.", "content": "The effect of spinal injury on employment in a heavy industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224175"} {"pmid": "4224176", "title": "A clinical trial of rotational manipulation of the spine in back pain cases occurring in a factory.", "content": "A clinical trial of rotational manipulation of the spine in back pain cases occurring in a factory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224176"} {"pmid": "4224177", "title": "Thin-layer gel filtration of proteins and mucopolysaccharides.", "content": "Thin-layer gel filtration of proteins and mucopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224177"} {"pmid": "4224178", "title": "Adrenal secretion rates of C-19 and C-21 steroids before and after hypophysectomy in the pig and the dog.", "content": "Adrenal secretion rates of C-19 and C-21 steroids before and after hypophysectomy in the pig and the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224178"} {"pmid": "4224179", "title": "The bacteriology of the gingival crevices of erupting human incisors.", "content": "The bacteriology of the gingival crevices of erupting human incisors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224179"} {"pmid": "4224180", "title": "Local factors of resistance in the gingival area.", "content": "Local factors of resistance in the gingival area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224180"} {"pmid": "4224181", "title": "Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation.", "content": "Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224181"} {"pmid": "4224182", "title": "Oxidative enzyme activities in keratinizing and non-keratinizing epithelium of normal and inflamed gingiva.", "content": "Oxidative enzyme activities in keratinizing and non-keratinizing epithelium of normal and inflamed gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224182"} {"pmid": "4224183", "title": "The vascular supply of the periodontal membrane. An investigation of the number and size of perforations in the alveolar wall.", "content": "The vascular supply of the periodontal membrane. An investigation of the number and size of perforations in the alveolar wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224183"} {"pmid": "4224184", "title": "Function of epithelial rests as suggested by their ultrastructure.", "content": "Function of epithelial rests as suggested by their ultrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224184"} {"pmid": "4224185", "title": "Condylar adaptation to a change in intermaxillary relationship.", "content": "Condylar adaptation to a change in intermaxillary relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224185"} {"pmid": "4224187", "title": "Holidays for the disabled.", "content": "Holidays for the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224187"} {"pmid": "4224186", "title": "Current titles in periodontology.", "content": "Current titles in periodontology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224186"} {"pmid": "4224196", "title": "Use of nicotinic acid and/or nicotinamide in high doses to treat schizophrenia.", "content": "Use of nicotinic acid and/or nicotinamide in high doses to treat schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224196"} {"pmid": "4224199", "title": "Palpation of umbilical cord through abdominal wall.", "content": "Palpation of umbilical cord through abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224199"} {"pmid": "4224198", "title": "The Women's Memorial of World War I.", "content": "The Women's Memorial of World War I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224198"} {"pmid": "4224200", "title": "Making able the disabled.", "content": "Making able the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224200"} {"pmid": "4224201", "title": "Sézary's reticulosis progressing to poikilodermia and mycosis fungoides.", "content": "Sézary's reticulosis progressing to poikilodermia and mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224201"} {"pmid": "4224204", "title": "General anaesthesia for children's dentistry.", "content": "General anaesthesia for children's dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224204"} {"pmid": "4224203", "title": "A bioassay of treatment of hemorrhagic shock. 3. Effects of a saline solution, ascorbic acid, and nicotinamide upon the toxicity of endotoxin for rats.", "content": "A bioassay of treatment of hemorrhagic shock. 3. Effects of a saline solution, ascorbic acid, and nicotinamide upon the toxicity of endotoxin for rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224203"} {"pmid": "4224206", "title": "Walker carcinosarcoma 256 in study of anticancer agents. II. Results.", "content": "Walker carcinosarcoma 256 in study of anticancer agents. II. Results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224206"} {"pmid": "4224207", "title": "Studies on the egg-membrane lysin of Tegula pfeifferi: isolation and chemical analysis of the egg membrane.", "content": "Studies on the egg-membrane lysin of Tegula pfeifferi: isolation and chemical analysis of the egg membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224207"} {"pmid": "4224208", "title": "Phospholipid involvement in gastric microsomal ATPase.", "content": "Phospholipid involvement in gastric microsomal ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224208"} {"pmid": "4224210", "title": "Participation of thymus in acid mucopolysaccharide metabolism.", "content": "Participation of thymus in acid mucopolysaccharide metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224210"} {"pmid": "4224211", "title": "Lysogenic properties of various Staphylococcus aureus phage-types.", "content": "Lysogenic properties of various Staphylococcus aureus phage-types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224211"} {"pmid": "4224212", "title": "Industrial dermatitis--its detection and control.", "content": "Industrial dermatitis--its detection and control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224212"} {"pmid": "4224214", "title": "Human effects of chronic, low dose radiation. Implications for adjudication of compensation claims for radiation injury.", "content": "Human effects of chronic, low dose radiation. Implications for adjudication of compensation claims for radiation injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224214"} {"pmid": "4224213", "title": "Pesticide exposure from concentrate spraying.", "content": "Pesticide exposure from concentrate spraying.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224213"} {"pmid": "4224215", "title": "Practical pointers on managing disabled patients.", "content": "Practical pointers on managing disabled patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224215"} {"pmid": "4224216", "title": "Goblet cell fine structure.", "content": "Goblet cell fine structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224216"} {"pmid": "4224218", "title": "Genetic recombination between alpha-toxin mutants of Staphylococcus aureus.", "content": "Genetic recombination between alpha-toxin mutants of Staphylococcus aureus. McClatchy, J. K. (The University of Texas Southwestern Medical School, Dallas), and E. D. Rosenblum. Genetic recombination between alpha-toxin mutants of Staphylococcus aureus. J. Bacteriol. 92:580-583. 1966.-A demonstration of genetic recombination between Staphylococcus aureus nonhemolytic mutants was attempted by means of transduction. The results of two-point reciprocal transductions placed the mutants into two genetic groups. Recombination within each group was not detectable within the limits of the method, but hemolytic recombinants were obtained in transductional crosses when donor and recipient were from different groups. At least two genetic loci are therefore involved in alpha-toxin production. The 11 mutants of group II were fibrinolysin-negative. The recombinants were always found to be restored to fibrinolysin production as well as to alpha-toxin production. These data suggest the existence of a pleiotropic gene simultaneously affecting the synthesis of both alpha toxin and fibrinolysin. The nine mutants of group I were fibrinolysin-positive. Group I members are postulated to be alpha-toxin structural mutants. Three mutants were also negative for bound coagulase, but no linkage was observed between the locus controlling bound coagulase and the loci for either fibrinolysin or alpha-toxin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224218"} {"pmid": "4224220", "title": "Use of tetrazolium for improved resolution of bacteriophage plaques.", "content": "Use of tetrazolium for improved resolution of bacteriophage plaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224220"} {"pmid": "4224219", "title": "Adenosine triphosphatase activity of mycoplasma membranes.", "content": "Adenosine triphosphatase activity of mycoplasma membranes. Rottem, Shlomo (Hebrew University, Jerusalem, Israel), and Shmuel Razin. Adenosine triphosphatase activity of mycoplasma membranes. J. Bacteriol. 92:714-722. 1966.-Adenosine triphosphatase activity of Mycoplasma laidlawii, M. gallisepticum, and Mycoplasma sp. strain 14 was confined to the cell membrane. The enzymatic activity was dependent on magnesium, but was not activated by sodium and potassium. Ouabain did not inhibit the adenosine triphosphatase activity of the mycoplasmas, and did not interfere with the active accumulation of potassium by M. laidlawii cells. Sulfhydryl-blocking reagents and fluoride inhibited the enzymatic activity, whereas 2,4-dinitrophenol was without any effect. Membranes of M. laidlawii hydrolyzed other nucleotide triphosphates and adenosine diphosphate (ADP), but at a lower rate than adenosine triphosphate (ATP). Nucleoside-2'-(3')-phosphates, ribose-5-phosphate, glucose-6-phosphate, and pyrophosphate were not hydrolyzed by the membrane preparations. It seems that the enzyme(s) involved in ATP hydrolysis by M. laidlawii membranes is strongly bound to the membrane subunits, which would account for the failure to purify the enzyme by protein fractionation techniques. The adenosine triphosphatase activity of mycoplasma membranes resembles in its properties that of similar enzymes studied in bacteria. The mycoplasma enzyme(s) seems to differ from the adenosine triphosphatase associated with ion transport in mammalian cell membranes and from mitochondrial adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224219"} {"pmid": "4224221", "title": "Fine structure of spongy degeneration of the central nervous system (van Bogaert and Bertrand type).", "content": "Fine structure of spongy degeneration of the central nervous system (van Bogaert and Bertrand type).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224221"} {"pmid": "4224223", "title": "Employers' liability for lunch-hour injury.", "content": "Employers' liability for lunch-hour injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224223"} {"pmid": "4224222", "title": "Heart disease and employment. The perspective of the occupational physician.", "content": "Heart disease and employment. The perspective of the occupational physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224222"} {"pmid": "4224224", "title": "Administration of the antimetabolite 6AN (6-aminonicotinamide) to horses.", "content": "Administration of the antimetabolite 6AN (6-aminonicotinamide) to horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224224"} {"pmid": "4224226", "title": "Nervous control of the mechanical properties of the abdominal wall at feeding in Rhodnius.", "content": "Nervous control of the mechanical properties of the abdominal wall at feeding in Rhodnius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224226"} {"pmid": "4224228", "title": "Unwanted effects of propranolol.", "content": "Unwanted effects of propranolol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224228"} {"pmid": "4224229", "title": "Comparative placental steroid synthesis. I. Conversion of (7-3-H)-dehydroepiandrosterone to (3-H)-androst-4-ene-3,17-dione.", "content": "Comparative placental steroid synthesis. I. Conversion of (7-3-H)-dehydroepiandrosterone to (3-H)-androst-4-ene-3,17-dione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224229"} {"pmid": "4224240", "title": "Catabolic metabolism of cholesterol in stomach cancer.", "content": "Catabolic metabolism of cholesterol in stomach cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224240"} {"pmid": "4224241", "title": "Histochemical studies of hydrolytic and oxidative enzymes in the human intestinal tumors.", "content": "Histochemical studies of hydrolytic and oxidative enzymes in the human intestinal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224241"} {"pmid": "4224242", "title": "Cardiac output in erythrodermic skin disease.", "content": "Cardiac output in erythrodermic skin disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224242"} {"pmid": "4224243", "title": "Influences of metabolic-effective agents on nucleotide systems in ocular tissues.", "content": "Influences of metabolic-effective agents on nucleotide systems in ocular tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224243"} {"pmid": "4224244", "title": "Exchanges of nucleotide phosphates in normal and in failing canine hearts.", "content": "Exchanges of nucleotide phosphates in normal and in failing canine hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224244"} {"pmid": "4224245", "title": "Cutaneous atrophy secondary to intra-articular corticosteroid administration.", "content": "Cutaneous atrophy secondary to intra-articular corticosteroid administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224245"} {"pmid": "4224250", "title": "The excretion of nondialyzable urinary mucopolysaccharide in rheumatic and other systemic disease states.", "content": "The excretion of nondialyzable urinary mucopolysaccharide in rheumatic and other systemic disease states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224250"} {"pmid": "4224249", "title": "Characterization of leukocyte glucose-6-phosphate dehydrogenase in normal and mutant human subjects.", "content": "Characterization of leukocyte glucose-6-phosphate dehydrogenase in normal and mutant human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224249"} {"pmid": "4224251", "title": "Elephantiasis nostras of the abdominal wall.", "content": "Elephantiasis nostras of the abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224251"} {"pmid": "4224246", "title": "Developmental highlights.", "content": "Developmental highlights.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224246"} {"pmid": "4224253", "title": "Mucopolysaccharidosis type 3. Morphologic and biochemical studies of two siblings with Sanfilippo syndrome.", "content": "Mucopolysaccharidosis type 3. Morphologic and biochemical studies of two siblings with Sanfilippo syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224253"} {"pmid": "4224255", "title": "Case records of the Massachusetts General Hospital. Case 54-1966.", "content": "Case records of the Massachusetts General Hospital. Case 54-1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224255"} {"pmid": "4224254", "title": "The sex chromosomes in evolution and in medicine.", "content": "The sex chromosomes in evolution and in medicine. The recent emergence of human cytogenetics has a firm foundation in studies on other forms of life. Historical highlights are Mendel's studies on the garden pea (published in 1865 but lost in an obscure journal until 1900); formulation of cytogenic postulates by Sutton and Boveri (1902-1903); Bridges' discovery of chromosome abnormalities in Drosophila (1916), followed by numerous similar studies in plants; and demonstration of the chromosomal basis of the syndromes of Down, Klinefelter and Turner in man (1959).The sex chromosomes (XX and XY) evolved from a pair of undifferentiated autosomes of a premammalian ancestor, the X chromosome changing less than the Y as they evolved. Eleven numerical abnormalities of the sex chromosomes are known in man, and knowledge of their effects on development is accumulating. The abnormal complexes range in size from the XO error of Turner's syndrome to the XXXXY error of a variant of Klinefelter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224254"} {"pmid": "4224247", "title": "The severely involved child: maternal backache.", "content": "The severely involved child: maternal backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224247"} {"pmid": "4224256", "title": "LH and adrenal androgenesis.", "content": "LH and adrenal androgenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224256"} {"pmid": "4224257", "title": "National Employ the Physically Handicapped Week: when America listens.", "content": "National Employ the Physically Handicapped Week: when America listens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224257"} {"pmid": "4224258", "title": "Hire the Handicapped Week: a critique.", "content": "Hire the Handicapped Week: a critique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224258"} {"pmid": "4224248", "title": "Emotional factors in residential care of handicapped children.", "content": "Emotional factors in residential care of handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224248"} {"pmid": "4224263", "title": "Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.", "content": "Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224263"} {"pmid": "4224264", "title": "Definitive surgical treatment of anomalous origin of left coronary artery from pulmonary artery: indications and results.", "content": "Definitive surgical treatment of anomalous origin of left coronary artery from pulmonary artery: indications and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224264"} {"pmid": "4224266", "title": "Hematoma of the rectus abdominis muscle complicated by anticoagulation therapy.", "content": "Hematoma of the rectus abdominis muscle complicated by anticoagulation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224266"} {"pmid": "4224265", "title": "Nonphosphorylating respiration of mitochondria from brown adipose tissue of rats.", "content": "Nonphosphorylating respiration of mitochondria from brown adipose tissue of rats. Mitochondria from brown adipose tissue of cold-acclimated rats (6 degrees C) oxidize alpha-ketoglutarate at a rate twice that of controls (26 degrees C). In both groups, however, the phosphorus: oxygen ratio with alpha-ketoglutarate never exceeded unity, and it is essentially zero with either succinate or alpha-glycerophosphate. Adenosine triphosphatase activity of these mitochondria is very low and it is not stimulated by 2,4-dinitrophenol. In addition, both respiration and phosphorylation are unaffected by adenosine diphosphate, 2,4-dinitrophenol, bovine serum albumin, or glutathione. Endogenous respiration of tissue slices is not stimulated by 2-4-dinitrophenol. It is suggested that brown fat mitochondria are not capable of oxidative phosphorylation, but do phosphorylate at the substrate level. Since these findings provide an unusual example of electron transport by means of an energetically nonconservative pathway, their significance to thermogenesis by brown adipose tissue is particularly emphasized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224265"} {"pmid": "4224267", "title": "Electrocardiographic changes reflecting left atrial abnormality in hypertension.", "content": "Electrocardiographic changes reflecting left atrial abnormality in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224267"} {"pmid": "4224270", "title": "The proteolysis of fibrinogen by plasmin: the identification of thrombin-clottable fibrinogen derivatives which polymerize abnormally.", "content": "The proteolysis of fibrinogen by plasmin: the identification of thrombin-clottable fibrinogen derivatives which polymerize abnormally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224270"} {"pmid": "4224271", "title": "The ionic requirements for the development of contracture in isolated slow muscle fibres of the frog.", "content": "The ionic requirements for the development of contracture in isolated slow muscle fibres of the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224271"} {"pmid": "4224273", "title": "Comparative pathophysiology of the paroxysmal EEG. Laminar analysis of the electrogenesis of spike and wave activity in the frog telencephalon.", "content": "Comparative pathophysiology of the paroxysmal EEG. Laminar analysis of the electrogenesis of spike and wave activity in the frog telencephalon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224273"} {"pmid": "4224272", "title": "Paroxysmal electrical activity in the isolated forebrain of the frog (rana temporaria). Comparative pathophysiology of the thalamic pacemaker of paroxysmal activity.", "content": "Paroxysmal electrical activity in the isolated forebrain of the frog (rana temporaria). Comparative pathophysiology of the thalamic pacemaker of paroxysmal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224272"} {"pmid": "4224274", "title": "The reactibility of rats with defined susceptibility to an acoustic epileptogenic stimulus--to some acoustic and optic stimuli.", "content": "The reactibility of rats with defined susceptibility to an acoustic epileptogenic stimulus--to some acoustic and optic stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224274"} {"pmid": "4224275", "title": "The effect of thalamic spreading depression on conduction in the visual and auditory pathways.", "content": "The effect of thalamic spreading depression on conduction in the visual and auditory pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224275"} {"pmid": "4224276", "title": "The effect of isoprenaline pretreatment on the size of acute myocardial necrosis induced by the same drug.", "content": "The effect of isoprenaline pretreatment on the size of acute myocardial necrosis induced by the same drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224276"} {"pmid": "4224277", "title": "Effect of chronic systemic hypoxia of the methaemoglobin type on the rat myocardium and its resistance to anoxia.", "content": "Effect of chronic systemic hypoxia of the methaemoglobin type on the rat myocardium and its resistance to anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224277"} {"pmid": "4224278", "title": "The respiratory metabolism of liver tissue slices and the total respiratory metabolism in rats after partial hepatectomy.", "content": "The respiratory metabolism of liver tissue slices and the total respiratory metabolism in rats after partial hepatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224278"} {"pmid": "4224279", "title": "Changes in the content of proteins, nucleic acids and the histological picture of the thyroid gland during the postnatal period in the rat.", "content": "Changes in the content of proteins, nucleic acids and the histological picture of the thyroid gland during the postnatal period in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224279"} {"pmid": "4224281", "title": "Changes in erythropoiesis after whole-body x-irradiation in rats and rabbits.", "content": "Changes in erythropoiesis after whole-body x-irradiation in rats and rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224281"} {"pmid": "4224282", "title": "The role of erythropoietin in changes of erythropoiesis after x-irradiation in rats and rabbits.", "content": "The role of erythropoietin in changes of erythropoiesis after x-irradiation in rats and rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224282"} {"pmid": "4224283", "title": "A device for measuring isometric contractions mechanoelectrically.", "content": "A device for measuring isometric contractions mechanoelectrically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224283"} {"pmid": "4224285", "title": "Supravalvular mitral stenosis associated with ventricular septal defect, subvalvular aortic stenosis and double aortic arch.", "content": "Supravalvular mitral stenosis associated with ventricular septal defect, subvalvular aortic stenosis and double aortic arch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224285"} {"pmid": "4224286", "title": "Endocardial fibroelastosis of the right ventricle in the newborn. Presenting the clinical picture of the hypoplastic right heart syndrome.", "content": "Endocardial fibroelastosis of the right ventricle in the newborn. Presenting the clinical picture of the hypoplastic right heart syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224286"} {"pmid": "4224287", "title": "Cystinuria associated with mongolism and identification of an abnormal pyrrolidine compound in urine.", "content": "Cystinuria associated with mongolism and identification of an abnormal pyrrolidine compound in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224287"} {"pmid": "4224288", "title": "Subcellular changes in surface adenosine triphosphatase activity of human liver in extrahepatic obstructive jaundice.", "content": "Subcellular changes in surface adenosine triphosphatase activity of human liver in extrahepatic obstructive jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224288"} {"pmid": "4224289", "title": "Methoxychlor toxicity. Comparative studies in the dog and the swine.", "content": "Methoxychlor toxicity. Comparative studies in the dog and the swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224289"} {"pmid": "4224290", "title": "Piglet birthweights and the order of farrowing.", "content": "Piglet birthweights and the order of farrowing. The relationship between birthweight and order of farrowing was determined from the records of 202 attended farrowings. Statistical analysis of all individual birthweights showed the first-born piglet to be heavier (P<0.05) than the last-born. The order of farrowing might not be entirely random, as further evidenced by a delayed expulsion of stillborn piglets; 70 per cent of these births occurred during the last third of the farrowing period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224290"} {"pmid": "4224291", "title": "Plaque formation by Teschen disease virus and the effect of certain associated factors.", "content": "Plaque formation by Teschen disease virus and the effect of certain associated factors. A plaque assay method was developed for Teschen disease virus using primary pig kidney cultures in which neutral red stain was incorporated in the agar overlay medium. Certain factors associated with the plaque-forming ability of the virus were standardized. Cultures allowed to adsorb the virus for 45-60 minutes at 28 and 37 C, gave maximal plaque count. The virus infected the cellular layer through the agar medium. Plating efficiency of the virus was enhanced by using a small volume of inoculum. Addition of serum to the medium was not required. Neutral red concentration in the agar overlay medium affected the number of plaques. Statistical analysis demonstrated the uniformity of the plaque counts and their linear relationship to virus concentration. Isolation of the virus by the plaque technique from infected spinal cord supernatant fluid was achieved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224291"} {"pmid": "4224292", "title": "Studies on transmissible gastroenteritis of swine. II. Selected characteristics of a cytopathogenic virus common to five isolates from transmissible gastroenteritis.", "content": "Studies on transmissible gastroenteritis of swine. II. Selected characteristics of a cytopathogenic virus common to five isolates from transmissible gastroenteritis. Five cell culture isolates from transmissible gastroenteritis (TGE) of swine have been studied. There is a cytopathogenic virus common to all of these isolates. Some of the characteristics of this virus, such as its size, approximately 100 mmicro, its relative sensitivity to ether, lability at pH 2, pH 3, and pH 10, and its heat lability suggest that it may be a member of the myxovirus class. Concurrent research in this laboratory indicates that this cytopathogenic virus is not the only virus involved in the etiology of TGE, but it appears to be associated with many of the outbreaks of TGE which have been studied by this laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224292"} {"pmid": "4224293", "title": "Studies of Escherichia coli in gnotobiotic pigs. I. Experimental reproduction of colibacillosis.", "content": "Studies of Escherichia coli in gnotobiotic pigs. I. Experimental reproduction of colibacillosis. The successful experimental production of colibacillosis in young gnotobiotic pigs by the oral administration of E. COLI (08:K.:H21 was accomplished. Colibacillosis was not produced in gnotobiotic pigs infected with either of the 2 other strains of E.COLI employed.Necropsy observations were presented and discussed. Emphasis was placed on the absence of grossly visible enteritis in pigs that died in the acute phase of the disease. The gross appearance of the intestinal tract changed some hours after death to resemble that associated with enteritis.Bacteremia was detected in the gnotobiotic pigs orally infected with each of the 3 strains of E. COLI, and the special characteristics of the colostrum-deprived pig were stressed as important factors in these findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224293"} {"pmid": "4224295", "title": "Bacteria in acne lesions.", "content": "Bacteria in acne lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224295"} {"pmid": "4224296", "title": "Down syndrome and congenital leukemia.", "content": "Down syndrome and congenital leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224296"} {"pmid": "4224300", "title": "Repair of potentially lethal damage in x-irradiated HeLa cells.", "content": "Repair of potentially lethal damage in x-irradiated HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224300"} {"pmid": "4224301", "title": "Sudden death from bronchial asthma.", "content": "Sudden death from bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224301"} {"pmid": "4224303", "title": "Erosion of the teeth.", "content": "Erosion of the teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224303"} {"pmid": "4224305", "title": "Digitonin precipitable steroids in normal human urine.", "content": "Digitonin precipitable steroids in normal human urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224305"} {"pmid": "4224307", "title": "Excretion of 16-alpha-hydroxysteroids by premature infants.", "content": "Excretion of 16-alpha-hydroxysteroids by premature infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224307"} {"pmid": "4224306", "title": "Thin-layer chromatography of 17-ketosteroid 2,4-dinitrophenylhydrazones.", "content": "Thin-layer chromatography of 17-ketosteroid 2,4-dinitrophenylhydrazones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224306"} {"pmid": "4224308", "title": "A histochemical study of polyphosphate hydrolases in epidermal dendritic cells.", "content": "A histochemical study of polyphosphate hydrolases in epidermal dendritic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224308"} {"pmid": "4224309", "title": "Double beds and backache.", "content": "Double beds and backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224309"} {"pmid": "4224310", "title": "Histochemical study of dentin in hydrocoritsone- and fluoride-treated rats.", "content": "Histochemical study of dentin in hydrocoritsone- and fluoride-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224310"} {"pmid": "4224314", "title": "Epiphyseal growth zones in acute lathyrism. Determinations of water, hydroxyproline and mucopolysaccharides.", "content": "Epiphyseal growth zones in acute lathyrism. Determinations of water, hydroxyproline and mucopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224314"} {"pmid": "4224312", "title": "The excretion of taurine during deoxypyridoxine administration in Downs' syndrome patients and controls.", "content": "The excretion of taurine during deoxypyridoxine administration in Downs' syndrome patients and controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224312"} {"pmid": "4224313", "title": "Generalized aminoaciduria in the magnesium deficient rat.", "content": "Generalized aminoaciduria in the magnesium deficient rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224313"} {"pmid": "4224320", "title": "Light sensitization and peroxides in sweat.", "content": "Light sensitization and peroxides in sweat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224320"} {"pmid": "4224326", "title": "Haemagglutination inhibition by antibody to host material of fowl plague virus grown in different tissues of chick chorioallantoic membranes.", "content": "Haemagglutination inhibition by antibody to host material of fowl plague virus grown in different tissues of chick chorioallantoic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224326"} {"pmid": "4224321", "title": "A quantitative study of muscle factors in the chronic low back syndrome.", "content": "A quantitative study of muscle factors in the chronic low back syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224321"} {"pmid": "4224322", "title": "Biochemical changes in the brain in rats poisoned with an alkymercury compound, with special reference to the inhibition of protein synthesis in brain cortex slices.", "content": "Biochemical changes in the brain in rats poisoned with an alkymercury compound, with special reference to the inhibition of protein synthesis in brain cortex slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224322"} {"pmid": "4224323", "title": "The death adder (Acanthophis antarcticus): the effect of the bite and its treatment.", "content": "The death adder (Acanthophis antarcticus): the effect of the bite and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224323"} {"pmid": "4224327", "title": "The significance of cardiac murmurs in anemia.", "content": "The significance of cardiac murmurs in anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224327"} {"pmid": "4224330", "title": "A new practical back brace.", "content": "A new practical back brace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224330"} {"pmid": "4224328", "title": "Controlled relaxation. II. Clinical management of muscle-relaxant administration.", "content": "Controlled relaxation. II. Clinical management of muscle-relaxant administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224328"} {"pmid": "4224329", "title": "Total-skin electron-beam therapy of lymphoma cutis and generalized psoriasis: clinical experiences and adverse reactions.", "content": "Total-skin electron-beam therapy of lymphoma cutis and generalized psoriasis: clinical experiences and adverse reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224329"} {"pmid": "4224331", "title": "Cardiovascular malformation and hydramnios.", "content": "Cardiovascular malformation and hydramnios.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224331"} {"pmid": "4224332", "title": "Total anomalous pulmonary venous drainage into the azygos vein.", "content": "Total anomalous pulmonary venous drainage into the azygos vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224332"} {"pmid": "4224334", "title": "Adenosinetriphosphatase activity of cardiac myosin. Comparison of the enzymatic activities and activation by actin of dog cardiac, rabbit cardiac, rabbit white skeletal and rabbit red skeletal muscle myosins.", "content": "Adenosinetriphosphatase activity of cardiac myosin. Comparison of the enzymatic activities and activation by actin of dog cardiac, rabbit cardiac, rabbit white skeletal and rabbit red skeletal muscle myosins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224334"} {"pmid": "4224335", "title": "A cholera epidemic without a hospital death.", "content": "A cholera epidemic without a hospital death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224335"} {"pmid": "4224336", "title": "A comparison of plasma lipoprotein levels in Asians, Africans and Europeans.", "content": "A comparison of plasma lipoprotein levels in Asians, Africans and Europeans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224336"} {"pmid": "4224337", "title": "Epidemiology of fractures in the Chinese children of Singapore.", "content": "Epidemiology of fractures in the Chinese children of Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224337"} {"pmid": "4224338", "title": "An epidemiological study of humeral fractures in Singapore.", "content": "An epidemiological study of humeral fractures in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224338"} {"pmid": "4224339", "title": "Responses of large and small intestine of the rat to cesium, 5-hydroxytryptamine ouabain and acetyl choline.", "content": "Responses of large and small intestine of the rat to cesium, 5-hydroxytryptamine ouabain and acetyl choline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224339"} {"pmid": "4224340", "title": "Veterinary parasitology in Malaysia with reference to cattle problems.", "content": "Veterinary parasitology in Malaysia with reference to cattle problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224340"} {"pmid": "4224341", "title": "Progressive eradication of malarial disease in New Guinea. Experience in Maprik.", "content": "Progressive eradication of malarial disease in New Guinea. Experience in Maprik.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224341"} {"pmid": "4224342", "title": "Plasmodium inui-like infection producing a presumably fatal illness in a leaf monkey Presbytis johnii--a previously undescribed host.", "content": "Plasmodium inui-like infection producing a presumably fatal illness in a leaf monkey Presbytis johnii--a previously undescribed host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224342"} {"pmid": "4224343", "title": "Separation of P. Berghei antigens by disc electrophoresis.", "content": "Separation of P. Berghei antigens by disc electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224343"} {"pmid": "4224344", "title": "Haemagglutination tests in malaria and toxoplasma: observations on sedimentation patterns.", "content": "Haemagglutination tests in malaria and toxoplasma: observations on sedimentation patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224344"} {"pmid": "4224345", "title": "The application of fluorescent antibody test to Balantidium coli using fluorescent isothiocyanate and rhodamine isothiocyanate.", "content": "The application of fluorescent antibody test to Balantidium coli using fluorescent isothiocyanate and rhodamine isothiocyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224345"} {"pmid": "4224346", "title": "A demonstration of the use of the polygraph to record Schultz-Dale reactions utilizing sera of monkeys infected with Brugia malayi as sources of both antibody and antigen.", "content": "A demonstration of the use of the polygraph to record Schultz-Dale reactions utilizing sera of monkeys infected with Brugia malayi as sources of both antibody and antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224346"} {"pmid": "4224347", "title": "A note on the preferred A. aegypti breeding habitats in urban areas in Malaysia.", "content": "A note on the preferred A. aegypti breeding habitats in urban areas in Malaysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224347"} {"pmid": "4224348", "title": "Development of Wuchereria bancrofti in the domestic cat.", "content": "Development of Wuchereria bancrofti in the domestic cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224348"} {"pmid": "4224350", "title": "Studies on filariasis in New Guinea. Observations on periodicity.", "content": "Studies on filariasis in New Guinea. Observations on periodicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224350"} {"pmid": "4224349", "title": "A note on an egg parasite of Megymenum subpurpurascens West (pentatomidae: Rhyncheta).", "content": "A note on an egg parasite of Megymenum subpurpurascens West (pentatomidae: Rhyncheta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224349"} {"pmid": "4224351", "title": "A double infection of filariasis in a black panther (Panthera pardus) from Pahang.", "content": "A double infection of filariasis in a black panther (Panthera pardus) from Pahang.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224351"} {"pmid": "4224352", "title": "A new filarial worm in the heart of a forest rat (Rattus sabanus).", "content": "A new filarial worm in the heart of a forest rat (Rattus sabanus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224352"} {"pmid": "4224353", "title": "A sheathed microfilaria from a tree-shrew (Tupaia glis).", "content": "A sheathed microfilaria from a tree-shrew (Tupaia glis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224353"} {"pmid": "4224354", "title": "Ascaris lumbricides eggs in liver and lungs of 2-year-old boy at necropsy. Confirmation by experimental inoculations of animals.", "content": "Ascaris lumbricides eggs in liver and lungs of 2-year-old boy at necropsy. Confirmation by experimental inoculations of animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224354"} {"pmid": "4224356", "title": "Comparison of developmental rates of two strains of Angiostrongylus cantonensis in the same laboratory-bred final hosts.", "content": "Comparison of developmental rates of two strains of Angiostrongylus cantonensis in the same laboratory-bred final hosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224356"} {"pmid": "4224355", "title": "Comparative susceptibility of primitive and higher primates to infection with Angiostrongylus cantonensis (Nematoda: Metastrongylidae).", "content": "Comparative susceptibility of primitive and higher primates to infection with Angiostrongylus cantonensis (Nematoda: Metastrongylidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224355"} {"pmid": "4224357", "title": "Studies on Stephanofilaria kaeli in cattle.", "content": "Studies on Stephanofilaria kaeli in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224357"} {"pmid": "4224358", "title": "Histopathology of Stephanofilaria kaeli lesions in cattle.", "content": "Histopathology of Stephanofilaria kaeli lesions in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224358"} {"pmid": "4224359", "title": "A study of the Nematode parasites of cockroaches in Singapore.", "content": "A study of the Nematode parasites of cockroaches in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224359"} {"pmid": "4224360", "title": "Demonstration of a Nematode, Muspicea Sp., from the skin of laboratory mice.", "content": "Demonstration of a Nematode, Muspicea Sp., from the skin of laboratory mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224360"} {"pmid": "4224361", "title": "Possible sources of human infection with Opisthorchis and Paragonimus in Malaya.", "content": "Possible sources of human infection with Opisthorchis and Paragonimus in Malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224361"} {"pmid": "4224362", "title": "Life cycle of a new Plagiorchid from Bulbuls and Swifts experimentally maintained in White-headed Munias and white mice.", "content": "Life cycle of a new Plagiorchid from Bulbuls and Swifts experimentally maintained in White-headed Munias and white mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224362"} {"pmid": "4224363", "title": "Differenation of Trematode cercariae of the Genus Plagiorchis by use of the patterns of their argentophilic cuticular structures.", "content": "Differenation of Trematode cercariae of the Genus Plagiorchis by use of the patterns of their argentophilic cuticular structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224363"} {"pmid": "4224364", "title": "Miracidial maze. Use of a free-choice system to test Echinostome miracidia in their relative attraction towards normal and abnormal snails hosts, living, dead, whole, and dissected snails.", "content": "Miracidial maze. Use of a free-choice system to test Echinostome miracidia in their relative attraction towards normal and abnormal snails hosts, living, dead, whole, and dissected snails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224364"} {"pmid": "4224365", "title": "Lung infection of rat with Cysticercus fasciolaris.", "content": "Lung infection of rat with Cysticercus fasciolaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224365"} {"pmid": "4224366", "title": "A Malayan record of Temnocephala semperi Weber (Rhabdocoela, Temnocephalidae), an ectocommensal turbellarian on the freshwater crab Potamon rafflesi Roux.", "content": "A Malayan record of Temnocephala semperi Weber (Rhabdocoela, Temnocephalidae), an ectocommensal turbellarian on the freshwater crab Potamon rafflesi Roux.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224366"} {"pmid": "4224370", "title": "Ambulation of \"ambulatory\" handicapped patients.", "content": "Ambulation of \"ambulatory\" handicapped patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224370"} {"pmid": "4224371", "title": "Hurler's syndrome. Effect of retinol (vitamin A alcohol) on cellular mucopolysaccharides in cultured human skin fibroblasts.", "content": "Hurler's syndrome. Effect of retinol (vitamin A alcohol) on cellular mucopolysaccharides in cultured human skin fibroblasts. Skin fibroblasts from eight families with Hurler's syndrome (X-linked recessive and autosomal recessive) and normal individuals have been studied in cell culture. A good correlation between cellular metachromasia and the quantitative estimation of intracellular mucopolysaccharides was observed provided the culture conditions were standardized. In both forms of Hurler's syndrome intracellular mucopolysaccharide content could be used to distinguish the affected individual and the carrier from the normal subject, although the total mucopolysaccharide content of fibroblast cultures or the amount in the culture medium did not permit such a distinction. Retinol, in concentrations similar to those encountered in man in hyper-vitaminosis A, caused a reduction in total mucopolysaccharide content of fibroblast cultures from normal and affected individuals. Cultures from three patients with the X-linked recessive form of Hurler's syndrome showed a gradual but marked decrease in cellular metachromasia and approximately 60% decrease in mucopolysaccharide content. Synthesis of polysaccharides and sulfation appeared to be equally affected. On removal of retinol from the medium the content of intracellular mucopolysaccharides returned to pretreatment levels. The possible relevance of these findings to the treatment of Hurler's syndrome is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224371"} {"pmid": "4224377", "title": "The response of various skin lesions to oral sulfur--35.", "content": "The response of various skin lesions to oral sulfur--35.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224377"} {"pmid": "4224378", "title": "Ultrastructure of myocardium in physiological hypertrophy of the heart in rats.", "content": "Ultrastructure of myocardium in physiological hypertrophy of the heart in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224378"} {"pmid": "4224384", "title": "Concentrations of amino acids in plasma and muscle. Relationship to androgen metabolism during growth and development in the male.", "content": "Concentrations of amino acids in plasma and muscle. Relationship to androgen metabolism during growth and development in the male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224384"} {"pmid": "4224452", "title": "Spontaneous atlanto-axial dislocation in a mongoloid child with spinal cord compression. Case report.", "content": "Spontaneous atlanto-axial dislocation in a mongoloid child with spinal cord compression. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224452"} {"pmid": "4224453", "title": "The return of the injured worker to work.", "content": "The return of the injured worker to work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224453"} {"pmid": "4224455", "title": "Effect of adrenal steroids on a Na+- and K+-requiring adenosine triphosphatase from rat kidney.", "content": "Effect of adrenal steroids on a Na+- and K+-requiring adenosine triphosphatase from rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224455"} {"pmid": "4224456", "title": "The plasmin inhibitor of human plasma. IV. Its action on plasmin, trypsin, chymotrypsin, and thrombin.", "content": "The plasmin inhibitor of human plasma. IV. Its action on plasmin, trypsin, chymotrypsin, and thrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224456"} {"pmid": "4224457", "title": "Treatment of cancer patients with infusions of plasmin.", "content": "Treatment of cancer patients with infusions of plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224457"} {"pmid": "4224458", "title": "Cardiac size and pulmonary arteriography in experimental chronic hypoxia.", "content": "Cardiac size and pulmonary arteriography in experimental chronic hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224458"} {"pmid": "4224459", "title": "Cerebral oxygen consumption in Down's syndrome.", "content": "Cerebral oxygen consumption in Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224459"} {"pmid": "4224461", "title": "Some general observations on the usefulness of lysergic acid in psychiatry.", "content": "Some general observations on the usefulness of lysergic acid in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224461"} {"pmid": "4224463", "title": "Pathologic physiology of valvular regurgitation.", "content": "Pathologic physiology of valvular regurgitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224463"} {"pmid": "4224465", "title": "The first appointment.", "content": "The first appointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224465"} {"pmid": "4224466", "title": "Children's dentistry--present and future trends.", "content": "Children's dentistry--present and future trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224466"} {"pmid": "4224467", "title": "Health or medical questionnaire.", "content": "Health or medical questionnaire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224467"} {"pmid": "4224469", "title": "Idiopathic and disseminated eczema.", "content": "Idiopathic and disseminated eczema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224469"} {"pmid": "4224471", "title": "Steroid hormone transformations by endocrine organs from pregnant mammals. I. Estrogen biosynthesis by mammalian placental preparations in vitro.", "content": "Steroid hormone transformations by endocrine organs from pregnant mammals. I. Estrogen biosynthesis by mammalian placental preparations in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224471"} {"pmid": "4224472", "title": "Crystallization and properties of rabbit skeletal muscle phosphofructokinase.", "content": "Crystallization and properties of rabbit skeletal muscle phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224472"} {"pmid": "4224470", "title": "In vivo parathyroid hormone status as related to respiration, phosphorylation and ion transport in rat kidney mitochondria.", "content": "In vivo parathyroid hormone status as related to respiration, phosphorylation and ion transport in rat kidney mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224470"} {"pmid": "4224473", "title": "Further analysis of the mode of inhibition and activation of Novikoff ascites tumor phosphofructokinase.", "content": "Further analysis of the mode of inhibition and activation of Novikoff ascites tumor phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224473"} {"pmid": "4224475", "title": "The determination of urinary androsterone, etiocholanolone, and dehydroepiandrosterone in the normal male rhesus monkey.", "content": "The determination of urinary androsterone, etiocholanolone, and dehydroepiandrosterone in the normal male rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224475"} {"pmid": "4224474", "title": "Catalysis of the direct transfer of oxygen from nicotinamide N-oxide to xanthine by xanthine oxidase.", "content": "Catalysis of the direct transfer of oxygen from nicotinamide N-oxide to xanthine by xanthine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224474"} {"pmid": "4224487", "title": "Studies on Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). Species described by Supino in 1897 from Burma, with special reference to H. (Rhipistoma) asiaticus (= H. dentipalpis Warburton and Nuttall).", "content": "Studies on Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). Species described by Supino in 1897 from Burma, with special reference to H. (Rhipistoma) asiaticus (= H. dentipalpis Warburton and Nuttall).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224487"} {"pmid": "4224486", "title": "Trasylol.", "content": "Trasylol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224486"} {"pmid": "4224485", "title": "Mitral valve replacement in a child during active rheumatic carditis: successful management of sixteen episodes of ventricular fibrillation.", "content": "Mitral valve replacement in a child during active rheumatic carditis: successful management of sixteen episodes of ventricular fibrillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224485"} {"pmid": "4224484", "title": "Metabolic factors in the cardiac insufficiency of arteriovenous fistula.", "content": "Metabolic factors in the cardiac insufficiency of arteriovenous fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224484"} {"pmid": "4224497", "title": "Alzheimer's disease in late adult life.", "content": "Alzheimer's disease in late adult life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224497"} {"pmid": "4224498", "title": "Giant left atrium as a cause of dysphagia.", "content": "Giant left atrium as a cause of dysphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224498"} {"pmid": "4224499", "title": "On the question of obstruction in idiopathic hypertrophic subaortic stenosis.", "content": "On the question of obstruction in idiopathic hypertrophic subaortic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224499"} {"pmid": "4224500", "title": "Sexual impotence in men having low-back syndrome.", "content": "Sexual impotence in men having low-back syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224500"} {"pmid": "4224503", "title": "Clothing for the handicapped.", "content": "Clothing for the handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224503"} {"pmid": "4224502", "title": "The experimental approach to the treatment and upbringing of handicapped children.", "content": "The experimental approach to the treatment and upbringing of handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224502"} {"pmid": "4224501", "title": "Giant T wave inversion.", "content": "Giant T wave inversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224501"} {"pmid": "4224504", "title": "Post-traumatic neurosis in industry.", "content": "Post-traumatic neurosis in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224504"} {"pmid": "4224505", "title": "Current Wisconsin legal concepts in industrial psychoneurosis.", "content": "Current Wisconsin legal concepts in industrial psychoneurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224505"} {"pmid": "4224506", "title": "The problem from the standpoint of the physician.", "content": "The problem from the standpoint of the physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224506"} {"pmid": "4224507", "title": "Responsibilities of the physician in workmen's compensation cases.", "content": "Responsibilities of the physician in workmen's compensation cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224507"} {"pmid": "4224508", "title": "Hemodynamic fndings in acute glomeruloenphritis.", "content": "Hemodynamic fndings in acute glomeruloenphritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224508"} {"pmid": "4224510", "title": "Hepatopexy for chronic cirrhotic ascites.", "content": "Hepatopexy for chronic cirrhotic ascites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224510"} {"pmid": "4224513", "title": "Aldosterone and sodium-potassium-dependent ATPase activity of rat kidney membranes.", "content": "Aldosterone and sodium-potassium-dependent ATPase activity of rat kidney membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224513"} {"pmid": "4224514", "title": "Extraction of contractile proteins from myofibrils prepared by rate-zonal centrifugation.", "content": "Extraction of contractile proteins from myofibrils prepared by rate-zonal centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224514"} {"pmid": "4224515", "title": "Unusual dermatoglyphics associated with major congenital malformations.", "content": "Unusual dermatoglyphics associated with major congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224515"} {"pmid": "4224516", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 53-1966.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 53-1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224516"} {"pmid": "4224519", "title": "Degenerative joint disease of the lumbar spine in coal miners--a clinical and x-ray study.", "content": "Degenerative joint disease of the lumbar spine in coal miners--a clinical and x-ray study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224519"} {"pmid": "4224520", "title": "Ankylosing spondylitis with widespread arteritis.", "content": "Ankylosing spondylitis with widespread arteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224520"} {"pmid": "4224521", "title": "Oscillations of glycolytic intermediates in yeast cells.", "content": "Oscillations of glycolytic intermediates in yeast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224521"} {"pmid": "4224522", "title": "Induction in Escherichia coli 15 of the colicinogenic factor by thymine-less death.", "content": "Induction in Escherichia coli 15 of the colicinogenic factor by thymine-less death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224522"} {"pmid": "4224523", "title": "Comparative studies of the MG activated ATPase activity and Ca uptake of fractions of white and red muscle homogenates.", "content": "Comparative studies of the MG activated ATPase activity and Ca uptake of fractions of white and red muscle homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224523"} {"pmid": "4224525", "title": "Studies on cytotropism in animal viruses. 3. Growth of influenza virus in epithelial-like and fibroblastic cells derived from chick embryo lung.", "content": "Studies on cytotropism in animal viruses. 3. Growth of influenza virus in epithelial-like and fibroblastic cells derived from chick embryo lung. Stewart, Robert B. (University of Rochester, Rochester, N.Y.), and Paul H. Frickey. Studies on cytotropism in animal viruses. III. Growth of influenza virus in epithelial-like and fibroblastic cells derived from chick embryo lung. J. Bacteriol. 92:972-977. 1966.-Growth of the PR8 strain of influenza virus was studied in epithelial-like and fibroblastic cell cultures derived from chick embryo lungs. The cells were found to differ in morphology, staining characteristics, and in their ability to support production of infectious influenza virus. Fibroblastic cells were characterized by their spindle shape, content of a mucopolysaccharide, their relative inability to synthesize infectious influenza virus, and production of a cell-associated noninfectious hemagglutinin. Epithelial-like cells were characterized by their polygonal shape, absence of mucopolysaccharide, and ability to synthesize infectious influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224525"} {"pmid": "4224528", "title": "The Mg2+--influence on the antibody biosynthesis in vitro inhibited by tetracyclines and chloramphenicol.", "content": "The Mg2+--influence on the antibody biosynthesis in vitro inhibited by tetracyclines and chloramphenicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224528"} {"pmid": "4224529", "title": "Inquiries into the insulin influence on the respiration and the synthesis of adenosine triphophate in cell nuclei isolated from thymus glands of calves.", "content": "Inquiries into the insulin influence on the respiration and the synthesis of adenosine triphophate in cell nuclei isolated from thymus glands of calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224529"} {"pmid": "4224530", "title": "On infections of tonsillar and odontic origin in the etiopathogenesis of experimental streptococcal myocarditis.", "content": "On infections of tonsillar and odontic origin in the etiopathogenesis of experimental streptococcal myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224530"} {"pmid": "4224531", "title": "Disturbances in the intensity of protein synthesis when the organism repeatedly comes into contact with streptococcal infection.", "content": "Disturbances in the intensity of protein synthesis when the organism repeatedly comes into contact with streptococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224531"} {"pmid": "4224533", "title": "Inquiries into the tuberculin sensitivity among medical students.", "content": "Inquiries into the tuberculin sensitivity among medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224533"} {"pmid": "4224526", "title": "Fibrinolytic and thrombolytic therapy.", "content": "Fibrinolytic and thrombolytic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224526"} {"pmid": "4224534", "title": "On the efficiency of the aqueous and alcoholic methods of morphine and strychnin extraction from visceral parts, when mixed with animal charcoal.", "content": "On the efficiency of the aqueous and alcoholic methods of morphine and strychnin extraction from visceral parts, when mixed with animal charcoal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224534"} {"pmid": "4224535", "title": "Assay of antibody production by surviving cells dispersed in agar gel.", "content": "Assay of antibody production by surviving cells dispersed in agar gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224535"} {"pmid": "4224539", "title": "An unusual abdominal flap.", "content": "An unusual abdominal flap.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224539"} {"pmid": "4224540", "title": "The influence of bilirubin on oxidative phosphorylation and related reactions in brain and liver mitochondria: effects of protein-binding.", "content": "The influence of bilirubin on oxidative phosphorylation and related reactions in brain and liver mitochondria: effects of protein-binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224540"} {"pmid": "4224542", "title": "Spontaneous functional closure of symptomatic atrial septal defects.", "content": "Spontaneous functional closure of symptomatic atrial septal defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224542"} {"pmid": "4224537", "title": "The distribution of hydroxysteroid dehydrogenase in human sebaceous glands.", "content": "The distribution of hydroxysteroid dehydrogenase in human sebaceous glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224537"} {"pmid": "4224538", "title": "Mucopolysaccharides in mast cells.", "content": "Mucopolysaccharides in mast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224538"} {"pmid": "4224561", "title": "Glycolytic control mechanisms. II. Kinetics of intermediate changes during the aerobic-anoxic transition in perfused rat heart.", "content": "Glycolytic control mechanisms. II. Kinetics of intermediate changes during the aerobic-anoxic transition in perfused rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224561"} {"pmid": "4224562", "title": "Some early findings on the possibility of using Aedes togoi as a vector of Dirofilaria repens in the laboratory.", "content": "Some early findings on the possibility of using Aedes togoi as a vector of Dirofilaria repens in the laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224562"} {"pmid": "4224563", "title": "The \"Innenkorper\" in differentiation between the microfilanriae of Brugia pahangi and B. malayi (sub-periodic form).", "content": "The \"Innenkorper\" in differentiation between the microfilanriae of Brugia pahangi and B. malayi (sub-periodic form).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224563"} {"pmid": "4224564", "title": "A filarial parasite from the flying fox (Pteropus vampyrus).", "content": "A filarial parasite from the flying fox (Pteropus vampyrus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224564"} {"pmid": "4224566", "title": "Congenital cataract.", "content": "Congenital cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224566"} {"pmid": "4224567", "title": "The Nadi reaction and mental subnormality.", "content": "The Nadi reaction and mental subnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224567"} {"pmid": "4224568", "title": "Historical background of injury as it relates to the workmen's compensation law.", "content": "Historical background of injury as it relates to the workmen's compensation law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224568"} {"pmid": "4224569", "title": "Current concepts of injury under the workmen's compensation act--the problem from the standpoint of industry.", "content": "Current concepts of injury under the workmen's compensation act--the problem from the standpoint of industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224569"} {"pmid": "4224575", "title": "Some bioelectrical properties of Amoeba proteus.", "content": "Some bioelectrical properties of Amoeba proteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224575"} {"pmid": "4224576", "title": "A study of maternal age in Down's syndrome.", "content": "A study of maternal age in Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224576"} {"pmid": "4224579", "title": "Urinary acid mucopolysaccharides in mastocytosis. A new technique for quantitative estimation.", "content": "Urinary acid mucopolysaccharides in mastocytosis. A new technique for quantitative estimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224579"} {"pmid": "4224570", "title": "Diagnostic value of phlebography in venous disorders of the lower extremity.", "content": "Diagnostic value of phlebography in venous disorders of the lower extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224570"} {"pmid": "4224586", "title": "Clot lysis with fibrinolysin: progress report.", "content": "Clot lysis with fibrinolysin: progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224586"} {"pmid": "4224578", "title": "On the possible rôle of the thyroid in the control of the development of the mammalian brain.", "content": "On the possible rôle of the thyroid in the control of the development of the mammalian brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224578"} {"pmid": "4224599", "title": "Observations on the spine in mongoloidism.", "content": "Observations on the spine in mongoloidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224599"} {"pmid": "4224601", "title": "\"Collagen disease\" due to carbamazepine (Tegretol).", "content": "\"Collagen disease\" due to carbamazepine (Tegretol).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224601"} {"pmid": "4224602", "title": "Sensitization, immunological tolerance and desensitization of guinea pigs to neoarsphenamine. II. Influence of various factors on sensitization to NEO.", "content": "Sensitization, immunological tolerance and desensitization of guinea pigs to neoarsphenamine. II. Influence of various factors on sensitization to NEO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224602"} {"pmid": "4224603", "title": "Toxoplasmin sensitivity: subnormality and environment.", "content": "Toxoplasmin sensitivity: subnormality and environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224603"} {"pmid": "4224604", "title": "Effects of maternal age and birth order on the risk of mongolism and leukemia.", "content": "Effects of maternal age and birth order on the risk of mongolism and leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224604"} {"pmid": "4224605", "title": "Light absorbance changes in pure mitochondria and other particulates of rat brain.", "content": "Light absorbance changes in pure mitochondria and other particulates of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224605"} {"pmid": "4224609", "title": "Studies on oestriol synthesis from dehydroepiandrosterone sulphate in human pregnancy.", "content": "Studies on oestriol synthesis from dehydroepiandrosterone sulphate in human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224609"} {"pmid": "4224610", "title": "Vascular connective tissue under the influence of oestrogens. II. Reaction of the aortic wall to noradrenaline-induced injury in female and male rabbits.", "content": "Vascular connective tissue under the influence of oestrogens. II. Reaction of the aortic wall to noradrenaline-induced injury in female and male rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224610"} {"pmid": "4224611", "title": "Myocardiopathy in Chagas' disease. I. Comparative study of pathologic findings in chronic human and experimental Chagas' myocarditis.", "content": "Myocardiopathy in Chagas' disease. I. Comparative study of pathologic findings in chronic human and experimental Chagas' myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224611"} {"pmid": "4224612", "title": "Clinical pathologic conference.", "content": "Clinical pathologic conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224612"} {"pmid": "4224613", "title": "Vasoinhibitory action of proteolytic enzyme inhibitors in the capillary bed.", "content": "Vasoinhibitory action of proteolytic enzyme inhibitors in the capillary bed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224613"} {"pmid": "4224621", "title": "The birth of mongoloids.", "content": "The birth of mongoloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224621"} {"pmid": "4224623", "title": "Studies on the adenosine triphosphatase activity of 14 S and 30 S dynein from cilia of Tetrahymena.", "content": "Studies on the adenosine triphosphatase activity of 14 S and 30 S dynein from cilia of Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224623"} {"pmid": "4224625", "title": "Stimulation of cerebrospinal fluid production by low doses of intraventricular ouabain.", "content": "Stimulation of cerebrospinal fluid production by low doses of intraventricular ouabain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224625"} {"pmid": "4224624", "title": "Absence of effects of cardiac glycosides on cardiac myosin and A Ca++-sensitive reconstituted cardiac actomyosin.", "content": "Absence of effects of cardiac glycosides on cardiac myosin and A Ca++-sensitive reconstituted cardiac actomyosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224624"} {"pmid": "4224626", "title": "Work and heart disease in Wisconsin. II. Workman's compensation rules of practice.", "content": "Work and heart disease in Wisconsin. II. Workman's compensation rules of practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224626"} {"pmid": "4224629", "title": "Histochemical investigation of ischemic villi in the placenta.", "content": "Histochemical investigation of ischemic villi in the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224629"} {"pmid": "4224630", "title": "The fibrinolytic enzyme system in the newborn.", "content": "The fibrinolytic enzyme system in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224630"} {"pmid": "4224636", "title": "Control of the activity of highly purified cardiac actomyosin by Ca2+, Na+ and K+.", "content": "Control of the activity of highly purified cardiac actomyosin by Ca2+, Na+ and K+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224636"} {"pmid": "4224637", "title": "An epidemiological assessment of bundle-branch block.", "content": "An epidemiological assessment of bundle-branch block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224637"} {"pmid": "4224635", "title": "Hematoma of the rectus abdominis muscle during anticoagulant therapy.", "content": "Hematoma of the rectus abdominis muscle during anticoagulant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224635"} {"pmid": "4224638", "title": "Left atrial volume and its changes in heart disease.", "content": "Left atrial volume and its changes in heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224638"} {"pmid": "4224639", "title": "Biochemical changes in phytohemagglutinin stimulated human lymphocytes.", "content": "Biochemical changes in phytohemagglutinin stimulated human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224639"} {"pmid": "4224640", "title": "The fine structure of the basal cell of human prostate.", "content": "The fine structure of the basal cell of human prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224640"} {"pmid": "4224628", "title": "Immunochemical studies of the circulating products of fibrinogenolysis in certain pathological conditions.", "content": "Immunochemical studies of the circulating products of fibrinogenolysis in certain pathological conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224628"} {"pmid": "4224654", "title": "An electromyographic diagnostic screening test in McArdle's disease and a case report.", "content": "An electromyographic diagnostic screening test in McArdle's disease and a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224654"} {"pmid": "4224655", "title": "Steroid mediated changes of leucocyte alkaline phosphatase activity in Down's syndrome.", "content": "Steroid mediated changes of leucocyte alkaline phosphatase activity in Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224655"} {"pmid": "4224657", "title": "Clinical definition of the Hurler-Hunter phenotypes. A review of 50 patients.", "content": "Clinical definition of the Hurler-Hunter phenotypes. A review of 50 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224657"} {"pmid": "4224658", "title": "Long bone growth in Down's syndrome.", "content": "Long bone growth in Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224658"} {"pmid": "4224659", "title": "Continuous oscillations in a cell-free extract of S. carlsbergensis.", "content": "Continuous oscillations in a cell-free extract of S. carlsbergensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224659"} {"pmid": "4224660", "title": "Red cell membrane ATPase: radiation inactivation estimates of \"size\".", "content": "Red cell membrane ATPase: radiation inactivation estimates of \"size\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224660"} {"pmid": "4224661", "title": "Disorders of the hair and scalp.", "content": "Disorders of the hair and scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224661"} {"pmid": "4224664", "title": "Sensitization, immunological tolerance and desensitization of guinea pigs to neoarsphenamine. I. Sensitization to NEO. Overall results and experiments on the skin testing technique.", "content": "Sensitization, immunological tolerance and desensitization of guinea pigs to neoarsphenamine. I. Sensitization to NEO. Overall results and experiments on the skin testing technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224664"} {"pmid": "4224678", "title": "Chromosomal mosaicism and Down's syndrome.", "content": "Chromosomal mosaicism and Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224678"} {"pmid": "4224680", "title": "Cultural characters of a newly recognized group of hospital staphylococci.", "content": "Cultural characters of a newly recognized group of hospital staphylococci. Members of a newly recognized group of hospital staphylococci, which are believed to have arisen from 83A staphylococci by lysogenization, differ from them in several cultural characters. Some but not all of these characters appear to be determined by the carriage of phage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224680"} {"pmid": "4224681", "title": "Coxsackie group B fatal neonatal myocarditis associated with cardiomegaly.", "content": "Coxsackie group B fatal neonatal myocarditis associated with cardiomegaly. Most fatal cases of Coxsackie group B neonatal myocarditis have been associated with nursery epidemics. Occasional sporadic cases have been reported, mainly from the U.S.A., and a further case with gross cardiomegaly is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224681"} {"pmid": "4224697", "title": "Dental management of the mentally retarded child.", "content": "Dental management of the mentally retarded child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224697"} {"pmid": "4224699", "title": "Specificity of Rv6 greater than Rv5 in the electrocardiographic recognition of left ventricular hypertrophy.", "content": "Specificity of Rv6 greater than Rv5 in the electrocardiographic recognition of left ventricular hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224699"} {"pmid": "4224701", "title": "Cerebral-palsied children respond well to treatment.", "content": "Cerebral-palsied children respond well to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224701"} {"pmid": "4224705", "title": "A survey of pediatric dentistry provided by Negro dentists in Texas.", "content": "A survey of pediatric dentistry provided by Negro dentists in Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224705"} {"pmid": "4224706", "title": "Dynamics of rheumatoid joint.", "content": "Dynamics of rheumatoid joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224706"} {"pmid": "4224708", "title": "Feulgen cytophotometric DNA determinations on human hearts.", "content": "Feulgen cytophotometric DNA determinations on human hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224708"} {"pmid": "4224709", "title": "Specialization and the physiatrist. Sixteenth John Stanley Coulter Memorial Lecture.", "content": "Specialization and the physiatrist. Sixteenth John Stanley Coulter Memorial Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224709"} {"pmid": "4224711", "title": "An analysis of impulse discharges from the spindle receptor.", "content": "An analysis of impulse discharges from the spindle receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224711"} {"pmid": "4224710", "title": "Isolation and characterization of a phosphorylated intermediate in the (Na+ + K+) system-dependent ATPase.", "content": "Isolation and characterization of a phosphorylated intermediate in the (Na+ + K+) system-dependent ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224710"} {"pmid": "4224712", "title": "Some observations on the electrical activity in the cardiac muscle fiber of horseshoe crab.", "content": "Some observations on the electrical activity in the cardiac muscle fiber of horseshoe crab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224712"} {"pmid": "4224713", "title": "Oxygen uptake in squirrel monkeys (Saimiri sciurea).", "content": "Oxygen uptake in squirrel monkeys (Saimiri sciurea).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224713"} {"pmid": "4224714", "title": "Establishment of a caesarean-derived, gnotobiote foster nursed inbred mouse colony with observations on the control of Pseudomonas.", "content": "Establishment of a caesarean-derived, gnotobiote foster nursed inbred mouse colony with observations on the control of Pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224714"} {"pmid": "4224715", "title": "Rana pipiens: health and disease.", "content": "Rana pipiens: health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224715"} {"pmid": "4224716", "title": "Restraining harness for dogs in metabolic studies involving radioactive materials.", "content": "Restraining harness for dogs in metabolic studies involving radioactive materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224716"} {"pmid": "4224717", "title": "Pseudomonas aeruginosa infection in rats used in radiobiology research.", "content": "Pseudomonas aeruginosa infection in rats used in radiobiology research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224717"} {"pmid": "4224718", "title": "A method for determining expected parturition date of rhesus monkeys, (Macaca mulatta).", "content": "A method for determining expected parturition date of rhesus monkeys, (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224718"} {"pmid": "4224720", "title": "Epidemiology of Staphylococcus aureus amongst New Guineans in the Gazelle peninsula.", "content": "Epidemiology of Staphylococcus aureus amongst New Guineans in the Gazelle peninsula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224720"} {"pmid": "4224719", "title": "Effects of peracetic acid used in gnotobiotics on experimental animals.", "content": "Effects of peracetic acid used in gnotobiotics on experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224719"} {"pmid": "4224722", "title": "The role of hormones in acne.", "content": "The role of hormones in acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224722"} {"pmid": "4224723", "title": "A study of heart disease in the Mulago hospital, Kampala, Uganda.", "content": "A study of heart disease in the Mulago hospital, Kampala, Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224723"} {"pmid": "4224728", "title": "Studies on myosin from red and white skeletal muscles of the rabbit. I. Adenosine triphosphatase activity.", "content": "Studies on myosin from red and white skeletal muscles of the rabbit. I. Adenosine triphosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224728"} {"pmid": "4224729", "title": "A contribution to the differential diagnosis of Hurler's disease and forms of Morquio's syndrome.", "content": "A contribution to the differential diagnosis of Hurler's disease and forms of Morquio's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224729"} {"pmid": "4224730", "title": "Familial Mongolism; with leukaemia in one member and a normal twinsib in another.", "content": "Familial Mongolism; with leukaemia in one member and a normal twinsib in another.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224730"} {"pmid": "4224731", "title": "Nebraska State Medical Association officers and committees.", "content": "Nebraska State Medical Association officers and committees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224731"} {"pmid": "4224732", "title": "Impressions of the National Health Plan in Scotland and England.", "content": "Impressions of the National Health Plan in Scotland and England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224732"} {"pmid": "4224734", "title": "The diagnosis and treatment of contact dermatitis.", "content": "The diagnosis and treatment of contact dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224734"} {"pmid": "4224733", "title": "Mortality patterns of middle-aged whites in Nebraska.", "content": "Mortality patterns of middle-aged whites in Nebraska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224733"} {"pmid": "4224735", "title": "Oxytocic infusion for induction and augmentation of labor.", "content": "Oxytocic infusion for induction and augmentation of labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224735"} {"pmid": "4224736", "title": "The use of embolectomy and thrombectomy catheters to relieve acute arterial and acute venous occlusion.", "content": "The use of embolectomy and thrombectomy catheters to relieve acute arterial and acute venous occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224736"} {"pmid": "4224737", "title": "Occupational dermatoses.", "content": "Occupational dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224737"} {"pmid": "4224738", "title": "The three R's of industrial injuries--rapport, rehabilitation, and reports.", "content": "The three R's of industrial injuries--rapport, rehabilitation, and reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224738"} {"pmid": "4224740", "title": "Workmen's compensation--a paradox.", "content": "Workmen's compensation--a paradox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224740"} {"pmid": "4224739", "title": "Heart trauma.", "content": "Heart trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224739"} {"pmid": "4224741", "title": "Psychiatric disability--fake or fact?", "content": "Psychiatric disability--fake or fact?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224741"} {"pmid": "4224749", "title": "A thirty-nine year old woman with a five year illness involving multiple organs.", "content": "A thirty-nine year old woman with a five year illness involving multiple organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224749"} {"pmid": "4224750", "title": "Diazepam in backache. A double-blind controlled trial.", "content": "Diazepam in backache. A double-blind controlled trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224750"} {"pmid": "4224751", "title": "Designing a public convenience for the disabled.", "content": "Designing a public convenience for the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224751"} {"pmid": "4224753", "title": "Studies on the mechanism of cellular death. 3. Changes in proteins and connective tissue elements during early and late cardiac necrosis.", "content": "Studies on the mechanism of cellular death. 3. Changes in proteins and connective tissue elements during early and late cardiac necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224753"} {"pmid": "4224754", "title": "Long-term results of valvuloplasty for mitral insufficiency in children.", "content": "Long-term results of valvuloplasty for mitral insufficiency in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224754"} {"pmid": "4224755", "title": "Subcellular particles in echinoderm tube feet. I. Class asteroidea.", "content": "Subcellular particles in echinoderm tube feet. I. Class asteroidea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224755"} {"pmid": "4224758", "title": "Effect of glucose on the level of glycolytic enzymes in yeast.", "content": "Effect of glucose on the level of glycolytic enzymes in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4224758"}